pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6831-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 4,000 7,164E-09 1,75E-05 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 3,000 1,08E-08 1,319E-05 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 3,000 2,51E-08 2,044E-05 ! cellular response to insulin stimulus GO:0032869 85 38 5,000 4,549E-08 2,778E-05 ! induction of positive chemotaxis GO:0050930 17 9 3,000 8,962E-08 4,379E-05 ! negative regulation of phosphorylation GO:0042326 52 24 4,000 1,458E-07 5,935E-05 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 3,000 1,488E-07 5,192E-05 ! response to insulin stimulus GO:0032868 98 47 5,000 1,701E-07 5,196E-05 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 4,000 2,237E-07 6,072E-05 GO:0045936|negative regulation of phosphate metabolic process, ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 3,000 2,328E-07 5,688E-05 ! negative regulation of glucose import GO:0046325 18 11 3,000 2,328E-07 5,17E-05 GO:0010829|negative regulation of glucose transport, ! insulin receptor signaling pathway GO:0008286 66 27 4,000 2,734E-07 5,565E-05 ! negative regulation of protein modification process GO:0031400 66 28 4,000 3,314E-07 6,228E-05 ! positive regulation of cellular catabolic process GO:0031331 34 12 3,000 3,478E-07 6,069E-05 ! regulation of positive chemotaxis GO:0050926 22 12 3,000 3,478E-07 5,664E-05 GO:0050927|positive regulation of positive chemotaxis, ! positive regulation of catabolic process GO:0009896 72 32 4,000 6,676E-07 1,019E-04 ! protein amino acid autophosphorylation GO:0046777 157 64 5,000 1,104E-06 1,586E-04 ! response to peptide hormone stimulus GO:0043434 129 64 5,000 1,104E-06 1,498E-04 ! positive regulation of glycolysis GO:0045821 13 5 2,000 1,399E-06 1,799E-04 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 3,000 2,098E-06 2,562E-04 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 3,000 2,098E-06 2,44E-04 ! regulation of intracellular protein transport GO:0033157 86 42 4,000 2,703E-06 3,002E-04 ! regulation of carbohydrate metabolic process GO:0006109 37 20 3,000 3,294E-06 3,499E-04 GO:0010675|regulation of cellular carbohydrate metabolic process, ! regulation of glucose import GO:0046324 30 20 3,000 3,294E-06 3,353E-04 GO:0010827|regulation of glucose transport, ! regulation of catabolic process GO:0009894 173 77 5,000 3,299E-06 3,224E-04 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 3,000 4,053E-06 3,808E-04 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 4,000 4,282E-06 3,875E-04 ! regulation of protein export from nucleus GO:0046825 10 7 2,000 4,859E-06 4,24E-04 ! positive regulation of locomotion GO:0040017 44 22 3,000 4,933E-06 4,156E-04 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! negative regulation of transport GO:0051051 164 85 5,000 5,878E-06 4,787E-04 ! cellular response to hormone stimulus GO:0032870 182 85 5,000 5,878E-06 4,632E-04 ! regulation of chemotaxis GO:0050920 45 23 3,000 5,947E-06 4,54E-04 ! regulation of cellular catabolic process GO:0031329 55 24 3,000 7,108E-06 5,262E-04 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 2,000 7,745E-06 5,565E-04 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 2,000 7,745E-06 5,406E-04 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 2,000 7,745E-06 5,256E-04 ! regulation of behavior GO:0050795 48 25 3,000 8,427E-06 5,564E-04 ! positive regulation of glucose metabolic process GO:0010907 18 9 2,000 1,157E-05 7,44E-04 ! regulation of glycolysis GO:0006110 20 9 2,000 1,157E-05 7,249E-04 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 2,000 1,157E-05 7,068E-04 ! regulation of intracellular transport GO:0032386 108 57 4,000 1,249E-05 7,44E-04 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 2,000 1,647E-05 9,579E-04 GO:0043470|regulation of carbohydrate catabolic process, ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 2,000 1,647E-05 9,357E-04 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 2,000 2,256E-05 1,252E-03 ! positive regulation of endothelial cell proliferation GO:0001938 23 11 2,000 2,256E-05 1,225E-03 ! chondrocyte differentiation GO:0002062 27 11 2,000 2,256E-05 1,198E-03 ! steroid hormone receptor signaling pathway GO:0030518 146 66 4,000 2,565E-05 1,333E-03 ! localization within membrane GO:0051668 26 12 2,000 2,996E-05 1,525E-03 ! negative regulation of protein kinase activity GO:0006469 144 69 4,000 3,186E-05 1,588E-03 ! negative regulation of kinase activity GO:0033673 145 70 4,000 3,416E-05 1,669E-03 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 4,000 3,659E-05 1,753E-03 ! aerobic respiration GO:0009060 56 36 3,000 3,751E-05 1,762E-03 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 2,000 3,88E-05 1,788E-03 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of monooxygenase activity GO:0032768 35 13 2,000 3,88E-05 1,755E-03 ! androgen receptor signaling pathway GO:0030521 81 37 3,000 4,189E-05 1,861E-03 ! negative regulation of transferase activity GO:0051348 155 74 4,000 4,471E-05 1,95E-03 ! N-terminal protein amino acid modification GO:0031365 30 15 2,000 6,125E-05 2,625E-03 ! negative regulation of bone remodeling GO:0046851 34 15 2,000 6,125E-05 2,58E-03 ! regulation of mRNA processing GO:0050684 26 15 2,000 6,125E-05 2,536E-03 ! regulation of the force of heart contraction GO:0002026 31 15 2,000 6,125E-05 2,494E-03 ! epithelial to mesenchymal transition GO:0001837 30 15 2,000 6,125E-05 2,453E-03 ! response to hypoxia GO:0001666 178 81 4,000 6,904E-05 2,72E-03 ! regulation of T cell differentiation GO:0045580 78 42 3,000 6,956E-05 2,697E-03 ! regulation of glucose metabolic process GO:0010906 28 16 2,000 7,51E-05 2,867E-03 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 2,000 7,51E-05 2,822E-03 ! negative regulation of tissue remodeling GO:0034104 37 16 2,000 7,51E-05 2,78E-03 ! response to oxygen levels GO:0070482 183 83 4,000 7,757E-05 2,829E-03 ! positive regulation of response to external stimulus GO:0032103 88 44 3,000 8,368E-05 3,006E-03 ! neutrophil chemotaxis GO:0030593 29 17 2,000 9,084E-05 3,216E-03 ! induction of apoptosis by intracellular signals GO:0008629 95 45 3,000 9,147E-05 3,192E-03 ! ATP synthesis coupled electron transport GO:0042773 69 45 3,000 9,147E-05 3,147E-03 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! regulation of protein transport GO:0051223 165 87 4,000 9,707E-05 3,294E-03 GO:0070201|regulation of establishment of protein localization, ! regulation of gene-specific transcription GO:0032583 102 46 3,000 9,977E-05 3,339E-03 ! positive regulation of cell cycle GO:0045787 96 48 3,000 1,18E-04 3,895E-03 ! regulation of lymphocyte differentiation GO:0045619 92 49 3,000 1,28E-04 4,168E-03 ! induction of apoptosis by extracellular signals GO:0008624 99 50 3,000 1,385E-04 4,453E-03 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 2,000 1,505E-04 4,776E-03 ! peptidyl-serine phosphorylation GO:0018105 44 20 2,000 1,505E-04 4,715E-03 ! regulation of protein localization GO:0032880 188 97 4,000 1,623E-04 5,019E-03 ! respiratory electron transport chain GO:0022904 83 53 3,000 1,74E-04 5,313E-03 ! negative regulation of intracellular transport GO:0032387 44 21 2,000 1,749E-04 5,276E-03 ! positive regulation of inflammatory response GO:0050729 41 21 2,000 1,749E-04 5,212E-03 ! positive regulation of protein catabolic process GO:0045732 44 22 2,000 2,018E-04 5,939E-03 ! inactivation of MAPK activity GO:0000188 45 22 2,000 2,018E-04 5,869E-03 ! positive regulation of intracellular transport GO:0032388 42 22 2,000 2,018E-04 5,8E-03 ! peptidyl-serine modification GO:0018209 50 22 2,000 2,018E-04 5,732E-03 ! regulation of protein catabolic process GO:0042176 126 56 3,000 2,156E-04 6,054E-03 ! positive regulation of DNA replication GO:0045740 44 23 2,000 2,312E-04 6,418E-03 ! positive regulation of cell migration GO:0030335 137 58 3,000 2,47E-04 6,78E-03 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 2,000 2,632E-04 7,144E-03 ! sex determination GO:0007530 48 24 2,000 2,632E-04 7,065E-03 ! regulation of oxidoreductase activity GO:0051341 48 24 2,000 2,632E-04 6,988E-03 ! negative regulation of bone resorption GO:0045779 10 5 1,000 2,696E-04 7,081E-03 ! cell adhesion mediated by integrin GO:0033627 10 5 1,000 2,696E-04 7,006E-03 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 1,000 2,696E-04 6,932E-03 ! anagen GO:0042640 7 5 1,000 2,696E-04 6,86E-03 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 1,000 2,696E-04 6,789E-03 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! microvillus organization GO:0032528 8 5 1,000 2,696E-04 6,72E-03 GO:0030033|microvillus assembly, ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 1,000 2,696E-04 6,652E-03 ! mRNA transcription GO:0009299 10 5 1,000 2,696E-04 6,585E-03 ! response to food GO:0032094 6 5 1,000 2,696E-04 6,52E-03 ! morphogenesis of an epithelial sheet GO:0002011 11 5 1,000 2,696E-04 6,456E-03 ! regulation of glycogen metabolic process GO:0070873 10 5 1,000 2,696E-04 6,394E-03 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of phospholipase A2 activity GO:0032429 15 5 1,000 2,696E-04 6,332E-03 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 1,000 2,696E-04 6,272E-03 ! virus-infected cell apoptosis GO:0006926 7 5 1,000 2,696E-04 6,213E-03 ! meiotic chromosome segregation GO:0045132 10 5 1,000 2,696E-04 6,155E-03 ! positive regulation of interleukin-4 production GO:0032753 9 5 1,000 2,696E-04 6,098E-03 GO:0032754|positive regulation of interleukin-5 production, ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 1,000 2,696E-04 6,042E-03 ! protein insertion into membrane GO:0051205 17 5 1,000 2,696E-04 5,987E-03 ! vasculogenesis GO:0001570 49 25 2,000 2,979E-04 6,557E-03 ! negative regulation of response to stimulus GO:0048585 106 61 3,000 3,001E-04 6,547E-03 ! response to endoplasmic reticulum stress GO:0034976 46 26 2,000 3,355E-04 7,253E-03 ! regulation of endothelial cell proliferation GO:0001936 60 27 2,000 3,76E-04 8,057E-03 ! positive regulation of cell motion GO:0051272 157 65 3,000 3,831E-04 8,138E-03 ! regulation of hormone biosynthetic process GO:0046885 10 6 1,000 4,03E-04 8,486E-03 ! neurofilament cytoskeleton organization GO:0060052 12 6 1,000 4,03E-04 8,414E-03 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 1,000 4,03E-04 8,342E-03 ! establishment of spindle localization GO:0051293 16 6 1,000 4,03E-04 8,272E-03 GO:0051653|spindle localization, ! neural nucleus development GO:0048857 19 6 1,000 4,03E-04 8,203E-03 ! regulation of interleukin-5 production GO:0032674 10 6 1,000 4,03E-04 8,136E-03 ! hair follicle maturation GO:0048820 8 6 1,000 4,03E-04 8,069E-03 ! regulation of interleukin-13 production GO:0032656 12 6 1,000 4,03E-04 8,003E-03 ! base conversion or substitution editing GO:0016553 6 6 1,000 4,03E-04 7,939E-03 ! cellular anion homeostasis GO:0030002 11 6 1,000 4,03E-04 7,875E-03 GO:0055081|anion homeostasis, ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 2,000 4,195E-04 8,133E-03 ! ER-nuclear signaling pathway GO:0006984 52 29 2,000 4,661E-04 8,965E-03 ! negative regulation of cell size GO:0045792 144 69 3,000 4,813E-04 9,186E-03 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 3,000 4,813E-04 9,115E-03 ! N-terminal protein amino acid acetylation GO:0006474 14 7 1,000 5,622E-04 0,01056483 ! mRNA stabilization GO:0048255 18 7 1,000 5,622E-04 0,01048418 GO:0043489|RNA stabilization, ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 1,000 5,622E-04 0,01040476 ! maintenance of protein location in nucleus GO:0051457 19 7 1,000 5,622E-04 0,01032653 ! male sex determination GO:0030238 15 7 1,000 5,622E-04 0,01024946 ! wound healing, spreading of epidermal cells GO:0035313 16 7 1,000 5,622E-04 0,01017354 ! G1 DNA damage checkpoint GO:0031571 20 7 1,000 5,622E-04 0,01009873 ! anterograde axon cargo transport GO:0008089 18 7 1,000 5,622E-04 0,01002502 ! negative regulation of interferon-gamma production GO:0032689 13 7 1,000 5,622E-04 9,952E-03 ! cranial nerve morphogenesis GO:0021602 12 7 1,000 5,622E-04 9,881E-03 ! positive regulation of monooxygenase activity GO:0032770 12 7 1,000 5,622E-04 9,81E-03 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 1,000 5,622E-04 9,741E-03 ! response to heat GO:0009408 54 31 2,000 5,689E-04 9,788E-03 ! regulation of protein import into nucleus GO:0042306 69 32 2,000 6,254E-04 0,01068418 ! leukocyte chemotaxis GO:0030595 55 33 2,000 6,853E-04 0,01162623 GO:0060326|cell chemotaxis, ! negative regulation of protein transport GO:0051224 74 33 2,000 6,853E-04 0,01154605 ! positive regulation of endothelial cell migration GO:0010595 19 8 1,000 7,47E-04 0,01249952 ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 1,000 7,47E-04 0,01241449 ! T-helper 1 type immune response GO:0042088 12 8 1,000 7,47E-04 0,01233061 ! ER overload response GO:0006983 13 8 1,000 7,47E-04 0,01224785 ! regulation of vascular permeability GO:0043114 12 8 1,000 7,47E-04 0,0121662 ! intermediate filament organization GO:0045109 12 8 1,000 7,47E-04 0,01208563 ! regulation of T cell differentiation in the thymus GO:0033081 14 8 1,000 7,47E-04 0,01200612 ! regulation of interleukin-4 production GO:0032673 18 8 1,000 7,47E-04 0,01192765 ! regulation of respiratory burst GO:0060263 12 8 1,000 7,47E-04 0,01185019 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 1,000 7,47E-04 0,01177374 ! negative regulation of MAP kinase activity GO:0043407 78 34 2,000 7,487E-04 0,01172534 ! placenta development GO:0001890 53 35 2,000 8,158E-04 0,01269407 ! positive regulation of phosphorylation GO:0042327 149 81 3,000 8,822E-04 0,01364045 ! mitotic sister chromatid segregation GO:0000070 63 36 2,000 8,865E-04 0,01362148 ! microtubule bundle formation GO:0001578 22 9 1,000 9,571E-04 0,01461413 ! retinoic acid receptor signaling pathway GO:0048384 16 9 1,000 9,571E-04 0,01452336 ! peptidyl-asparagine modification GO:0018196 15 9 1,000 9,571E-04 0,01443371 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! nucleoside bisphosphate metabolic process GO:0033865 18 9 1,000 9,571E-04 0,01434516 ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 1,000 9,571E-04 0,01425769 ! regulation of smooth muscle cell proliferation GO:0048660 64 37 2,000 9,611E-04 0,01422962 ! sister chromatid segregation GO:0000819 65 37 2,000 9,611E-04 0,0141439 ! tissue remodeling GO:0048771 78 37 2,000 9,611E-04 0,01405921 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 3,000 9,665E-04 0,01405477 GO:0045937|positive regulation of phosphate metabolic process, ! positive regulation of DNA metabolic process GO:0051054 77 38 2,000 1,039E-03 0,01502587 ! glycogen metabolic process GO:0005977 63 38 2,000 1,039E-03 0,01493748 ! glucan metabolic process GO:0044042 64 39 2,000 1,122E-03 0,01602603 GO:0006073|cellular glucan metabolic process, ! regulation of developmental growth GO:0048638 16 10 1,000 1,192E-03 0,01693469 ! regulation of smooth muscle cell migration GO:0014910 27 10 1,000 1,192E-03 0,01683681 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 1,000 1,192E-03 0,01674004 ! lung alveolus development GO:0048286 26 10 1,000 1,192E-03 0,01664439 ! glucan biosynthetic process GO:0009250 14 10 1,000 1,192E-03 0,01654981 GO:0005978|glycogen biosynthetic process, ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 1,000 1,192E-03 0,01645631 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 1,000 1,192E-03 0,01636386 ! motor axon guidance GO:0008045 22 10 1,000 1,192E-03 0,01627244 ! regulation of bone resorption GO:0045124 25 10 1,000 1,192E-03 0,01618204 ! protein heterooligomerization GO:0051291 17 10 1,000 1,192E-03 0,01609264 ! regulation of fat cell differentiation GO:0045598 18 10 1,000 1,192E-03 0,01600422 ! mRNA cleavage GO:0006379 18 10 1,000 1,192E-03 0,01591676 ! cellular respiration GO:0045333 143 88 3,000 1,202E-03 0,01595752 ! protein localization in nucleus GO:0034504 192 89 3,000 1,253E-03 0,01655095 ! mesenchymal cell development GO:0014031 94 41 2,000 1,298E-03 0,0170544 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! oxidative phosphorylation GO:0006119 152 90 3,000 1,306E-03 0,01706624 ! ossification GO:0001503 205 91 3,000 1,361E-03 0,01768417 ! bone development GO:0060348 206 92 3,000 1,417E-03 0,01831586 ! blood vessel remodeling GO:0001974 30 11 1,000 1,452E-03 0,01867265 ! peptide or protein amino-terminal blocking GO:0018409 22 11 1,000 1,452E-03 0,01857488 ! negative regulation of ossification GO:0030279 27 11 1,000 1,452E-03 0,01847814 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 1,000 1,452E-03 0,0183824 ! negative regulation of tumor necrosis factor production GO:0032720 16 11 1,000 1,452E-03 0,01828764 ! positive regulation of leukocyte migration GO:0002687 28 11 1,000 1,452E-03 0,01819386 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 1,000 1,452E-03 0,01810103 ! regulation of embryonic development GO:0045995 35 11 1,000 1,452E-03 0,01800915 ! positive regulation of MAP kinase activity GO:0043406 174 93 3,000 1,475E-03 0,01819527 ! epithelial cell differentiation GO:0030855 83 43 2,000 1,492E-03 0,01831302 ! energy reserve metabolic process GO:0006112 76 44 2,000 1,595E-03 0,01947994 ! negative regulation of multicellular organismal process GO:0051241 174 95 3,000 1,595E-03 0,01938559 ! regulation of T cell activation GO:0050863 175 96 3,000 1,658E-03 0,02004701 ! regulation of epithelial cell proliferation GO:0050678 122 45 2,000 1,702E-03 0,0204843 ! virus-host interaction GO:0019048 30 12 1,000 1,737E-03 0,02079767 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 1,000 1,737E-03 0,02069622 ! cranial nerve development GO:0021545 23 12 1,000 1,737E-03 0,02059575 ! histone acetylation GO:0016573 27 12 1,000 1,737E-03 0,02049625 ! autonomic nervous system development GO:0048483 24 12 1,000 1,737E-03 0,02039771 ! regulation of hormone metabolic process GO:0032350 28 12 1,000 1,737E-03 0,02030012 ! peptidyl-lysine modification GO:0018205 21 12 1,000 1,737E-03 0,02020345 ! T cell homeostasis GO:0043029 28 12 1,000 1,737E-03 0,0201077 ! regulation of leukocyte migration GO:0002685 29 12 1,000 1,737E-03 0,02001285 ! negative regulation of mast cell proliferation GO:0070667 24 12 1,000 1,737E-03 0,01991889 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 1,000 1,737E-03 0,01982582 ! embryonic placenta development GO:0001892 21 12 1,000 1,737E-03 0,0197336 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 2,000 1,814E-03 0,02051585 ! leukocyte migration GO:0050900 75 46 2,000 1,814E-03 0,0204213 ! positive regulation of protein transport GO:0051222 80 46 2,000 1,814E-03 0,02032763 ! nucleoside triphosphate catabolic process GO:0009143 22 13 1,000 2,045E-03 0,02281687 ! regulation of erythrocyte differentiation GO:0045646 47 13 1,000 2,045E-03 0,02271316 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 1,000 2,045E-03 0,02261039 ! regulation of mRNA stability GO:0043488 32 13 1,000 2,045E-03 0,02250854 ! positive regulation of defense response GO:0031349 88 48 2,000 2,051E-03 0,02246916 ! regulation of inflammatory response GO:0050727 84 48 2,000 2,051E-03 0,02236885 ! positive regulation of cytokine production GO:0001819 94 50 2,000 2,307E-03 0,02504355 ! lipid localization GO:0010876 32 14 1,000 2,378E-03 0,02570656 GO:0019915|lipid storage, ! negative regulation of protein import into nucleus GO:0042308 33 14 1,000 2,378E-03 0,02559331 ! cell wall macromolecule catabolic process GO:0016998 16 14 1,000 2,378E-03 0,02548106 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 1,000 2,378E-03 0,02536979 ! regulation of T-helper 2 type immune response GO:0002828 25 14 1,000 2,378E-03 0,02525949 ! regulation of RNA stability GO:0043487 33 14 1,000 2,378E-03 0,02515014 ! response to temperature stimulus GO:0009266 84 51 2,000 2,441E-03 0,02570739 ! positive regulation of growth GO:0045927 96 53 2,000 2,725E-03 0,02857472 ! cartilage development GO:0051216 99 53 2,000 2,725E-03 0,02845261 ! G1/S transition checkpoint GO:0031575 37 15 1,000 2,735E-03 0,02842748 ! intermediate filament cytoskeleton organization GO:0045104 34 15 1,000 2,735E-03 0,02830703 ! positive regulation of oxidoreductase activity GO:0051353 22 15 1,000 2,735E-03 0,02818759 ! intestinal absorption GO:0050892 31 15 1,000 2,735E-03 0,02806915 ! lymphocyte homeostasis GO:0002260 33 15 1,000 2,735E-03 0,02795171 ! cell wall macromolecule metabolic process GO:0044036 17 15 1,000 2,735E-03 0,02783524 ! regulation of angiogenesis GO:0045765 125 54 2,000 2,875E-03 0,02913966 ! regulation of muscle contraction GO:0006937 94 54 2,000 2,875E-03 0,02901925 ! response to UV GO:0009411 120 55 2,000 3,029E-03 0,03045054 ! bone remodeling GO:0046849 28 16 1,000 3,114E-03 0,03118279 ! heterophilic cell adhesion GO:0007157 43 16 1,000 3,114E-03 0,03105552 ! intermediate filament-based process GO:0045103 36 16 1,000 3,114E-03 0,03092927 ! axon cargo transport GO:0008088 46 16 1,000 3,114E-03 0,03080405 ! positive regulation of protein import into nucleus GO:0042307 34 16 1,000 3,114E-03 0,03067984 ! mRNA splice site selection GO:0006376 44 16 1,000 3,114E-03 0,03055663 ! regulation of T-helper cell differentiation GO:0045622 30 16 1,000 3,114E-03 0,03043441 ! negative regulation of leukocyte proliferation GO:0070664 32 16 1,000 3,114E-03 0,03031315 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! regulation of DNA replication GO:0006275 105 56 2,000 3,188E-03 0,03090678 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 2,000 3,352E-03 0,032371 ! regulation of bone remodeling GO:0046850 143 57 2,000 3,352E-03 0,03224355 ! negative regulation of cell cycle process GO:0010948 35 17 1,000 3,518E-03 0,03369997 ! gene silencing by RNA GO:0031047 38 17 1,000 3,518E-03 0,03356833 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 1,000 3,518E-03 0,03343772 ! regulation of survival gene product expression GO:0045884 38 17 1,000 3,518E-03 0,03330811 ! negative regulation of microtubule depolymerization GO:0007026 50 17 1,000 3,518E-03 0,03317951 GO:0031114|regulation of microtubule depolymerization, ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 1,000 3,518E-03 0,0330519 ! negative regulation of homeostatic process GO:0032845 36 17 1,000 3,518E-03 0,03292526 ! cellular polysaccharide metabolic process GO:0044264 93 58 2,000 3,522E-03 0,03283842 ! regulation of tissue remodeling GO:0034103 146 58 2,000 3,522E-03 0,03271356 ! maintenance of location GO:0051235 124 58 2,000 3,522E-03 0,03258965 ! DNA catabolic process GO:0006308 94 60 2,000 3,876E-03 0,03573244 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 1,000 3,944E-03 0,03622 ! nerve development GO:0021675 34 18 1,000 3,944E-03 0,03608435 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 1,000 3,944E-03 0,03594971 ! positive regulation of proteolysis GO:0045862 36 18 1,000 3,944E-03 0,03581606 ! response to retinoic acid GO:0032526 31 18 1,000 3,944E-03 0,03568341 ! cell-substrate junction assembly GO:0007044 56 18 1,000 3,944E-03 0,03555174 ! regulation of heart contraction GO:0008016 123 61 2,000 4,061E-03 0,03647409 ! regulation of homeostatic process GO:0032844 148 62 2,000 4,251E-03 0,03804291 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 1,000 4,393E-03 0,03916451 ! memory GO:0007613 34 19 1,000 4,393E-03 0,0390221 ! mitotic chromosome condensation GO:0007076 37 19 1,000 4,393E-03 0,03888071 ! response to vitamin A GO:0033189 32 19 1,000 4,393E-03 0,03874035 ! neuromuscular junction development GO:0007528 43 19 1,000 4,393E-03 0,038601 ! regulation of endothelial cell migration GO:0010594 45 19 1,000 4,393E-03 0,03846264 ! protein export from nucleus GO:0006611 40 19 1,000 4,393E-03 0,03832527 ! protein import into nucleus, docking GO:0000059 42 20 1,000 4,864E-03 0,04228668 ! phosphoinositide phosphorylation GO:0046854 40 20 1,000 4,864E-03 0,04213673 ! protein amino acid acetylation GO:0006473 41 20 1,000 4,864E-03 0,04198783 ! response to vitamin GO:0033273 36 20 1,000 4,864E-03 0,04183999 ! apoptotic mitochondrial changes GO:0008637 42 20 1,000 4,864E-03 0,04169318 ! cellular response to unfolded protein GO:0034620 35 20 1,000 4,864E-03 0,0415474 GO:0030968|endoplasmic reticulum unfolded protein response, ! positive regulation of myeloid cell differentiation GO:0045639 63 20 1,000 4,864E-03 0,04140264 ! estrogen receptor signaling pathway GO:0030520 45 20 1,000 4,864E-03 0,04125888 ! negative regulation of T cell activation GO:0050868 41 20 1,000 4,864E-03 0,04111611 ! negative regulation of translation GO:0017148 32 20 1,000 4,864E-03 0,04097433 ! negative regulation of cell growth GO:0030308 142 67 2,000 5,283E-03 0,0443533 ! chromosome segregation GO:0007059 127 67 2,000 5,283E-03 0,0442014 ! lipid phosphorylation GO:0046834 43 21 1,000 5,357E-03 0,04467018 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 1,000 5,357E-03 0,04451824 ! negative regulation of angiogenesis GO:0016525 49 21 1,000 5,357E-03 0,04436733 ! lung development GO:0030324 165 69 2,000 5,734E-03 0,04732821 ! homeostasis of number of cells GO:0048872 131 69 2,000 5,734E-03 0,04716886 ! microtubule-based transport GO:0010970 59 22 1,000 5,873E-03 0,04814732 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 1,000 5,873E-03 0,0479863 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 1,000 5,873E-03 0,04782634 ! response to cytokine stimulus GO:0034097 69 22 1,000 5,873E-03 0,04766745 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 1,000 5,873E-03 0,04750961 ! germ cell development GO:0007281 133 70 2,000 5,968E-03 0,0481215 ! activation of pro-apoptotic gene products GO:0008633 51 23 1,000 6,41E-03 0,05151508 ! regulation of bone mineralization GO:0030500 54 23 1,000 6,41E-03 0,05134618 ! negative regulation of cytokine production GO:0001818 41 23 1,000 6,41E-03 0,05117838 ! respiratory tube development GO:0030323 171 72 2,000 6,453E-03 0,05135362 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 2,000 6,961E-03 0,05521453 ! respiratory system development GO:0060541 175 74 2,000 6,961E-03 0,05503584 ! positive regulation of cell adhesion GO:0045785 61 24 1,000 6,969E-03 0,05492202 ! regulation of tumor necrosis factor production GO:0032680 37 24 1,000 6,969E-03 0,05474542 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 1,000 6,969E-03 0,05456995 ! learning or memory GO:0007611 161 76 2,000 7,492E-03 0,05847597 ! protein import into nucleus, translocation GO:0000060 51 25 1,000 7,549E-03 0,05873581 ! leukocyte adhesion GO:0007159 55 25 1,000 7,549E-03 0,05854935 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 1,000 7,549E-03 0,05836406 ! chromosome condensation GO:0030261 48 25 1,000 7,549E-03 0,05817995 ! regulation of alpha-beta T cell activation GO:0046634 48 25 1,000 7,549E-03 0,05799699 ! interaction with host GO:0051701 66 25 1,000 7,549E-03 0,05781518 ! regulation of biomineral formation GO:0070167 56 25 1,000 7,549E-03 0,05763451 ! leukocyte homeostasis GO:0001776 50 25 1,000 7,549E-03 0,05745496 ! protein tetramerization GO:0051262 57 25 1,000 7,549E-03 0,05727653 ! myelination GO:0042552 50 26 1,000 8,15E-03 0,06164602 ! molting cycle process GO:0022404 52 26 1,000 8,15E-03 0,06145576 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! regulation of transcription factor import into nucleus GO:0042990 58 26 1,000 8,15E-03 0,06126666 ! digestive system process GO:0022600 49 26 1,000 8,15E-03 0,06107873 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 1,000 8,15E-03 0,06089194 ! response to estradiol stimulus GO:0032355 43 26 1,000 8,15E-03 0,0607063 ! positive regulation of nuclear division GO:0051785 41 26 1,000 8,15E-03 0,06052178 GO:0045840|positive regulation of mitosis, ! protein oligomerization GO:0051259 149 79 2,000 8,332E-03 0,06168282 ! negative regulation of organelle organization GO:0010639 181 80 2,000 8,624E-03 0,06365029 ! regulation of interferon-gamma production GO:0032649 43 27 1,000 8,772E-03 0,06455157 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 1,000 8,772E-03 0,06435772 ! cellular response to oxidative stress GO:0034599 43 27 1,000 8,772E-03 0,06416503 ! regulation of chromosome organization GO:0033044 49 27 1,000 8,772E-03 0,06397349 ! negative regulation of lymphocyte activation GO:0051250 55 27 1,000 8,772E-03 0,0637831 ! protein import into nucleus GO:0006606 174 82 2,000 9,225E-03 0,06687734 ! spliceosomal snRNP biogenesis GO:0000387 40 28 1,000 9,415E-03 0,06804983 ! protein amino acid acylation GO:0043543 59 28 1,000 9,415E-03 0,06784909 ! dendrite development GO:0016358 67 28 1,000 9,415E-03 0,06764953 ! positive regulation of T cell differentiation GO:0045582 48 28 1,000 9,415E-03 0,06745115 ! peptidyl-tyrosine modification GO:0018212 57 28 1,000 9,415E-03 0,06725392 ! nuclear import GO:0051170 177 83 2,000 9,535E-03 0,06791336 ! T cell activation GO:0042110 189 84 2,000 9,851E-03 0,06995808 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 1,000 0,01007788 0,07136309 ! somitogenesis GO:0001756 52 29 1,000 0,01007788 0,07115684 ! negative regulation of growth GO:0045926 168 85 2,000 0,01017258 0,07161848 ! positive regulation of cell activation GO:0050867 161 86 2,000 0,01050038 0,07371389 GO:0002696|positive regulation of leukocyte activation, ! positive regulation of multicellular organism growth GO:0040018 55 30 1,000 0,01076088 0,07532618 ! tissue homeostasis GO:0001894 50 30 1,000 0,01076088 0,07511097 GO:0048871|multicellular organismal homeostasis, ! cell junction assembly GO:0034329 85 31 1,000 0,01146378 0,07978919 ! male gonad development GO:0008584 56 31 1,000 0,01146378 0,07956251 ! erythrocyte differentiation GO:0030218 62 31 1,000 0,01146378 0,07933712 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 1,000 0,01146378 0,07911301 ! natural killer cell activation GO:0030101 50 31 1,000 0,01146378 0,07889015 ! ensheathment of neurons GO:0007272 64 31 1,000 0,01146378 0,07866855 GO:0008366|axon ensheathment, ! negative regulation of leukocyte activation GO:0002695 60 31 1,000 0,01146378 0,07844819 ! positive regulation of protein modification process GO:0031401 156 90 2,000 0,0118725 0,08101824 ! response to unfolded protein GO:0006986 139 90 2,000 0,0118725 0,08079256 ! regulation of cell cycle process GO:0010564 161 90 2,000 0,0118725 0,08056814 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 1,000 0,01218633 0,08246874 ! spindle organization GO:0007051 50 32 1,000 0,01218633 0,08224093 ! metanephros development GO:0001656 81 32 1,000 0,01218633 0,08201437 ! peripheral nervous system development GO:0007422 68 32 1,000 0,01218633 0,08178905 ! hindbrain development GO:0030902 65 32 1,000 0,01218633 0,08156497 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 1,000 0,01218633 0,08134212 ! gene silencing GO:0016458 71 32 1,000 0,01218633 0,08112048 ! positive regulation of gene-specific transcription GO:0043193 70 33 1,000 0,01292834 0,08582589 ! response to ionizing radiation GO:0010212 74 33 1,000 0,01292834 0,0855933 ! spliceosome assembly GO:0000245 75 34 1,000 0,01368956 0,09038811 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 1,000 0,01368956 0,09014448 ! regulation of defense response GO:0031347 171 95 2,000 0,01372602 0,09014161 ! response to protein stimulus GO:0051789 158 96 2,000 0,01411533 0,09244973 ! DNA damage checkpoint GO:0000077 78 35 1,000 0,01446979 0,09451791 ! regulation of synaptic plasticity GO:0048167 78 35 1,000 0,01446979 0,09426587 ! calcium-mediated signaling GO:0019722 67 35 1,000 0,01446979 0,09401516 ! regulation of DNA metabolic process GO:0051052 188 97 2,000 0,01451086 0,09403194 ! interphase of mitotic cell cycle GO:0051329 224 98 2,000 0,01491264 0,09637984 ! regulation of proteolysis GO:0030162 77 36 1,000 0,01526881 0,09842135 ! skeletal muscle tissue development GO:0007519 223 100 2,000 0,01573496 0,10115925 GO:0060538|skeletal muscle organ development, ! mRNA transport GO:0051028 185 100 2,000 0,01573496 0,10089374 ! cell junction organization GO:0034330 96 37 1,000 0,01608639 0,1028771 ! maintenance of protein location in cell GO:0032507 89 37 1,000 0,01608639 0,10260849 ! regulation of microtubule-based process GO:0032886 86 37 1,000 0,01608639 0,10234128 ! negative regulation of cell activation GO:0050866 69 37 1,000 0,01608639 0,10207546 ! meiosis I GO:0007127 74 38 1,000 0,01692233 0,1071017 ! embryonic skeletal system morphogenesis GO:0048704 68 38 1,000 0,01692233 0,10682495 ! DNA integrity checkpoint GO:0031570 82 38 1,000 0,01692233 0,10654963 ! mitotic cell cycle checkpoint GO:0007093 76 39 1,000 0,01777642 0,11163956 ! carbohydrate homeostasis GO:0033500 59 39 1,000 0,01777642 0,1113533 GO:0042593|glucose homeostasis, ! nucleotide catabolic process GO:0009166 70 39 1,000 0,01777642 0,11106851 ! erythrocyte homeostasis GO:0034101 75 39 1,000 0,01777642 0,11078517 ! mammary gland development GO:0030879 93 40 1,000 0,01864844 0,11592399 ! nucleus organization GO:0006997 73 40 1,000 0,01864844 0,11562977 ! regulation of action potential in neuron GO:0019228 80 40 1,000 0,01864844 0,11533703 ! maintenance of protein location GO:0045185 95 41 1,000 0,01953818 0,12053477 ! RNA modification GO:0009451 64 41 1,000 0,01953818 0,12023116 ! T cell differentiation GO:0030217 93 42 1,000 0,02044544 0,125498 ! dorsal/ventral pattern formation GO:0009953 75 42 1,000 0,02044544 0,12518347 ! cytokinesis GO:0000910 84 42 1,000 0,02044544 0,12487051 ! response to xenobiotic stimulus GO:0009410 63 42 1,000 0,02044544 0,12455912 ! positive regulation of transcription factor activity GO:0051091 71 43 1,000 0,02137001 0,12986799 GO:0090047|positive regulation of transcription regulator activity, ! protein amino acid N-linked glycosylation GO:0006487 71 43 1,000 0,02137001 0,12954574 ! glucose transport GO:0015758 66 43 1,000 0,02137001 0,12922508 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 1,000 0,02137001 0,12890601 ! development of primary male sexual characteristics GO:0046546 80 43 1,000 0,02137001 0,12858851 ! regulation of T cell proliferation GO:0042129 80 43 1,000 0,02137001 0,12827256 ! segmentation GO:0035282 78 43 1,000 0,02137001 0,12795817 ! regulation of myeloid cell differentiation GO:0045637 105 43 1,000 0,02137001 0,12764531 ! negative regulation of protein complex disassembly GO:0043242 113 44 1,000 0,02231169 0,13294501 ! hexose transport GO:0008645 68 44 1,000 0,02231169 0,13262154 GO:0015749|monosaccharide transport, ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 1,000 0,02327027 0,13798368 ! developmental growth GO:0048589 88 45 1,000 0,02327027 0,13764958 ! maintenance of location in cell GO:0051651 101 45 1,000 0,02327027 0,13731709 ! negative regulation of cell migration GO:0030336 122 46 1,000 0,02424556 0,14272748 ! polysaccharide biosynthetic process GO:0000271 79 46 1,000 0,02424556 0,14238439 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 0,02589379 0,15169909 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 0,02589379 0,15133618 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 0,02589379 0,15097499 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,02589379 0,15061553 ! positive regulation of helicase activity GO:0051096 12 5 0,000 0,02589379 0,15025777 ! neuron fate determination GO:0048664 7 5 0,000 0,02589379 0,14990171 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02589379 0,14954733 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 0,02589379 0,14919463 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 0,02589379 0,14884358 ! polyol transport GO:0015791 12 5 0,000 0,02589379 0,14849418 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,02589379 0,14814642 ! response to superoxide GO:0000303 10 5 0,000 0,02589379 0,14780028 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 0,02589379 0,14745576 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 0,02589379 0,14711284 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,02589379 0,14677151 ! female meiosis GO:0007143 10 5 0,000 0,02589379 0,14643176 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,02589379 0,14609358 ! hypothalamus development GO:0021854 9 5 0,000 0,02589379 0,14575696 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 0,02589379 0,14542189 ! cobalt ion transport GO:0006824 11 5 0,000 0,02589379 0,14508835 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 0,02589379 0,14475634 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 0,02589379 0,14442585 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,02589379 0,14409686 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 0,02589379 0,14376937 ! embryonic camera-type eye development GO:0031076 12 5 0,000 0,02589379 0,14344336 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,02589379 0,14311883 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02589379 0,14279576 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 0,02589379 0,14247415 ! transposition GO:0032196 9 5 0,000 0,02589379 0,14215398 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 0,02589379 0,14183525 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 0,000 0,02589379 0,14151794 ! negative chemotaxis GO:0050919 16 5 0,000 0,02589379 0,14120206 ! positive regulation of histone modification GO:0031058 6 5 0,000 0,02589379 0,14088758 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,02589379 0,14057449 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 0,02589379 0,1402628 ! behavioral response to pain GO:0048266 10 5 0,000 0,02589379 0,13995248 ! clathrin coat assembly GO:0048268 15 5 0,000 0,02589379 0,13964353 ! Notch receptor processing GO:0007220 11 5 0,000 0,02589379 0,13933595 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02589379 0,13902972 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 0,02589379 0,13872483 ! micturition GO:0060073 9 5 0,000 0,02589379 0,13842127 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,02589379 0,13811904 ! copulation GO:0007620 9 5 0,000 0,02589379 0,13781813 ! glial cell fate commitment GO:0021781 14 5 0,000 0,02589379 0,13751852 ! protein maturation by protein folding GO:0022417 14 5 0,000 0,02589379 0,13722022 ! bioluminescence GO:0008218 9 5 0,000 0,02589379 0,13692321 ! spermidine metabolic process GO:0008216 7 5 0,000 0,02589379 0,13662748 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,02589379 0,13633302 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,02589379 0,13603983 ! apoptotic cell clearance GO:0043277 23 5 0,000 0,02589379 0,1357479 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,02589379 0,13545722 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 0,02589379 0,13516778 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,02589379 0,13487958 ! grooming behavior GO:0007625 6 5 0,000 0,02589379 0,1345926 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 0,02589379 0,13430684 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,02589379 0,13402229 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 0,02589379 0,13373895 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02589379 0,1334568 ! response to protozoan GO:0001562 13 5 0,000 0,02589379 0,13317583 ! lymph vessel development GO:0001945 10 5 0,000 0,02589379 0,13289605 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 0,02589379 0,13261744 ! endochondral ossification GO:0001958 17 5 0,000 0,02589379 0,13234 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,02589379 0,13206372 ! single strand break repair GO:0000012 8 5 0,000 0,02589379 0,13178859 ! parathyroid gland development GO:0060017 14 5 0,000 0,02589379 0,1315146 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,02589379 0,13124175 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,02589379 0,13097002 ! cytokine secretion GO:0050663 15 5 0,000 0,02589379 0,13069942 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 0,02589379 0,13042994 ! ceramide catabolic process GO:0046514 7 5 0,000 0,02589379 0,13016157 ! skeletal myofibril assembly GO:0014866 12 5 0,000 0,02589379 0,12989429 ! smooth muscle tissue development GO:0048745 32 5 0,000 0,02589379 0,12962812 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,02589379 0,12936303 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,02589379 0,12909902 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,02589379 0,12883609 ! cardiac muscle fiber development GO:0048739 12 5 0,000 0,02589379 0,12857423 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,02589379 0,12831343 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 9 5 0,000 0,02589379 0,12805369 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,02589379 0,12779499 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,02589379 0,12753734 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 0,02589379 0,12728073 ! glycine biosynthetic process GO:0006545 7 5 0,000 0,02589379 0,12702514 ! valine metabolic process GO:0006573 12 5 0,000 0,02589379 0,12677058 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 0,02589379 0,12651704 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 0,02589379 0,12626451 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 0,02589379 0,12601299 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 0,02589379 0,12576247 ! polyol catabolic process GO:0046174 9 5 0,000 0,02589379 0,12551294 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 0,02589379 0,1252644 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 0,02589379 0,12501684 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 0,02589379 0,12477026 ! muscle cell migration GO:0014812 8 5 0,000 0,02589379 0,12452465 ! mitochondrial fission GO:0000266 8 5 0,000 0,02589379 0,12428 ! sister chromatid cohesion GO:0007062 15 5 0,000 0,02589379 0,12403632 ! response to tumor necrosis factor GO:0034612 10 5 0,000 0,02589379 0,12379358 ! nerve growth factor processing GO:0032455 9 5 0,000 0,02589379 0,1235518 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 0,02589379 0,12331096 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 0,02589379 0,12307105 ! anaerobic glycolysis GO:0019642 6 5 0,000 0,02589379 0,12283208 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,02589379 0,12259403 ! monocyte activation GO:0042117 10 5 0,000 0,02589379 0,12235691 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,02589379 0,1221207 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,02589379 0,1218854 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,02589379 0,121651 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02589379 0,12141751 ! forebrain neuron development GO:0021884 13 5 0,000 0,02589379 0,12118491 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,02589379 0,1209532 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,02589379 0,12072237 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02589379 0,12049242 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 0,02589379 0,12026335 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,02589379 0,12003514 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 0,02589379 0,11980781 ! lipid glycosylation GO:0030259 7 5 0,000 0,02589379 0,11958133 ! nucleobase transport GO:0015851 6 5 0,000 0,02589379 0,1193557 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02589379 0,11913093 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 0,02589379 0,11890699 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 0,02589379 0,1186839 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 0,02589379 0,11846165 ! basic amino acid transport GO:0015802 12 5 0,000 0,02589379 0,11824023 ! cellular glucose homeostasis GO:0001678 6 5 0,000 0,02589379 0,11801963 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 0,02589379 0,11779985 ! actin nucleation GO:0045010 11 5 0,000 0,02589379 0,11758089 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,02589379 0,11736275 ! depurination GO:0045007 5 5 0,000 0,02589379 0,11714541 ! depyrimidination GO:0045008 10 5 0,000 0,02589379 0,11692887 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,02589379 0,11671314 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02589379 0,1164982 ! G2/M transition checkpoint GO:0031576 8 5 0,000 0,02589379 0,11628405 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,02589379 0,11607068 ! zinc ion homeostasis GO:0055069 9 5 0,000 0,02589379 0,1158581 GO:0006882|cellular zinc ion homeostasis, ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 0,02589379 0,11564629 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02589379 0,11543526 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,02589379 0,11522499 ! activated T cell proliferation GO:0050798 16 5 0,000 0,02589379 0,11501549 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,02589379 0,11480675 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 0,02589379 0,11459877 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,02589379 0,11439154 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02589379 0,11418506 ! gamma-delta T cell activation GO:0046629 6 5 0,000 0,02589379 0,11397932 ! response to arsenic GO:0046685 11 5 0,000 0,02589379 0,11377432 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 0,02589379 0,11357006 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,02589379 0,11336653 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 0,02589379 0,11316372 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 0,02589379 0,11296165 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 0,02589379 0,11276029 ! response to mercury ion GO:0046689 8 5 0,000 0,02589379 0,11255965 ! response to cadmium ion GO:0046686 7 5 0,000 0,02589379 0,11235972 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 0,02589379 0,1121605 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 0,02589379 0,11196198 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 0,02589379 0,11176417 ! bile acid biosynthetic process GO:0006699 7 5 0,000 0,02589379 0,11156706 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 0,02589379 0,11137064 ! ganglioside catabolic process GO:0006689 12 5 0,000 0,02589379 0,11117491 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,02589379 0,11097986 ! decidualization GO:0046697 11 5 0,000 0,02589379 0,1107855 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 0,02589379 0,11059182 ! protein autoprocessing GO:0016540 8 5 0,000 0,02589379 0,11039882 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 0,02589379 0,11020648 ! embryonic cleavage GO:0040016 6 5 0,000 0,02589379 0,11001482 ! peroxisome fission GO:0016559 5 5 0,000 0,02589379 0,10982382 ! histone demethylation GO:0016577 13 5 0,000 0,02589379 0,10963349 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 0,02589379 0,10944381 ! mitotic recombination GO:0006312 9 5 0,000 0,02589379 0,10925479 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 0,02589379 0,10906642 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,02589379 0,10887869 ! metaphase plate congression GO:0051310 7 5 0,000 0,02589379 0,10869162 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02589379 0,10850518 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,02589379 0,10831939 ! enteric nervous system development GO:0048484 8 5 0,000 0,02589379 0,10813422 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 0,02589379 0,10794969 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 0,02589379 0,10776579 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 0,02589379 0,10758252 ! muscle cell proliferation GO:0033002 12 5 0,000 0,02589379 0,10739987 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,02589379 0,10721783 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 0,02589379 0,10703641 ! B cell homeostasis GO:0001782 13 5 0,000 0,02589379 0,10685561 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 0,02589379 0,10667542 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,02589379 0,10649583 ! metaphase GO:0051323 11 5 0,000 0,02589379 0,10631684 ! melatonin biosynthetic process GO:0030187 7 5 0,000 0,02589379 0,10613846 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 0,02589379 0,10596067 ! cellular response to nutrient GO:0031670 8 5 0,000 0,02589379 0,10578348 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,02589379 0,10560688 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 0,02589379 0,10543087 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 0,02589379 0,10525544 ! regulation of hair follicle development GO:0051797 10 5 0,000 0,02589379 0,1050806 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 0,02589379 0,10490634 ! response to redox state GO:0051775 6 5 0,000 0,02589379 0,10473265 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 0,02589379 0,10455954 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 0,02589379 0,104387 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,02589379 0,10421503 ! brown fat cell differentiation GO:0050873 7 5 0,000 0,02589379 0,10404362 ! regulation of telomerase activity GO:0051972 7 5 0,000 0,02589379 0,10387278 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02589379 0,10370249 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 0,02589379 0,10353277 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02589379 0,1033636 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 0,02589379 0,10319498 ! striatum development GO:0021756 14 5 0,000 0,02589379 0,10302691 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 0,02589379 0,10285938 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,02589379 0,1026924 ! glial cell migration GO:0008347 10 5 0,000 0,02589379 0,10252597 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,02589379 0,10236007 ! neural plate morphogenesis GO:0001839 7 5 0,000 0,02589379 0,1021947 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 0,02589379 0,10202987 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,02589379 0,10186557 ! T cell activation during immune response GO:0002286 9 5 0,000 0,02589379 0,1017018 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,02589379 0,10153856 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,02589379 0,10137584 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 0,02589379 0,10121363 ! neuroprotection GO:0043526 8 5 0,000 0,02589379 0,10105195 ! regulation of sensory perception GO:0051931 8 5 0,000 0,02589379 0,10089078 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,02589379 0,10073013 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,02589379 0,10056999 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 0,02589379 0,10041035 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 0,02589379 0,10025122 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,02589379 0,1000926 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 0,02589379 0,09993447 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,02589379 0,09977685 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 0,02589379 0,09961972 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 0,02589379 0,09946308 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,02589379 0,09930694 ! spindle assembly GO:0051225 6 5 0,000 0,02589379 0,09915129 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,02589379 0,09899612 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,02589379 0,09884144 ! protein palmitoylation GO:0018345 12 5 0,000 0,02589379 0,09868724 ! drug metabolic process GO:0017144 7 5 0,000 0,02589379 0,09853352 ! stem cell division GO:0017145 11 5 0,000 0,02589379 0,09838028 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,02589379 0,09822752 ! organ regeneration GO:0031100 7 5 0,000 0,02589379 0,09807523 ! carnitine metabolic process GO:0009437 8 5 0,000 0,02589379 0,09792341 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,02589379 0,09777206 ! endosome transport GO:0016197 127 48 1,000 0,02624546 0,09894699 ! positive regulation of DNA binding GO:0043388 83 48 1,000 0,02624546 0,09879453 ! vascular process in circulatory system GO:0003018 85 48 1,000 0,02624546 0,09864254 ! male sex differentiation GO:0046661 93 48 1,000 0,02624546 0,09849101 ! regulation of adaptive immune response GO:0002819 92 48 1,000 0,02624546 0,09833995 ! regulation of mast cell proliferation GO:0070666 89 49 1,000 0,02726967 0,10202114 ! protein homooligomerization GO:0051260 84 49 1,000 0,02726967 0,10186514 ! regulation of action potential GO:0001508 102 50 1,000 0,0283098 0,10558908 ! regulation of ossification GO:0030278 123 50 1,000 0,0283098 0,10542812 ! regulation of gene expression, epigenetic GO:0040029 116 50 1,000 0,0283098 0,10526765 ! peptide metabolic process GO:0006518 80 51 1,000 0,02936566 0,10902782 ! negative regulation of immune system process GO:0002683 101 51 1,000 0,02936566 0,10886238 ! positive regulation of binding GO:0051099 88 52 1,000 0,03043705 0,1126632 ! response to estrogen stimulus GO:0043627 98 52 1,000 0,03043705 0,11249276 ! regulation of protein complex disassembly GO:0043244 127 52 1,000 0,03043705 0,11232283 ! histone modification GO:0016570 104 52 1,000 0,03043705 0,11215341 ! ribonucleoprotein complex assembly GO:0022618 104 52 1,000 0,03043705 0,11198451 ! amino acid activation GO:0043038 98 52 1,000 0,03043705 0,11181611 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,03099195 0,1136837 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,03099195 0,11351326 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 0,03099195 0,11334333 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 0,03099195 0,11317391 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,03099195 0,11300499 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 0,03099195 0,11283658 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 0,03099195 0,11266867 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,03099195 0,11250125 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 0,03099195 0,11233434 ! response to oxygen radical GO:0000305 11 6 0,000 0,03099195 0,11216792 ! positive regulation of axon extension GO:0045773 13 6 0,000 0,03099195 0,11200199 ! myoblast cell fate commitment GO:0048625 18 6 0,000 0,03099195 0,11183655 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 0,03099195 0,1116716 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 0,03099195 0,11150713 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,03099195 0,11134315 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 0,03099195 0,11117965 ! forebrain regionalization GO:0021871 9 6 0,000 0,03099195 0,11101663 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,03099195 0,11085409 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,03099195 0,11069202 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 0,03099195 0,11053043 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,03099195 0,1103693 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 0,03099195 0,11020865 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 0,03099195 0,11004846 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 0,03099195 0,10988874 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 0,03099195 0,10972948 ! malate metabolic process GO:0006108 13 6 0,000 0,03099195 0,10957068 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 0,03099195 0,10941235 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 0,03099195 0,10925446 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 0,03099195 0,10909704 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 0,03099195 0,10894006 ! protein refolding GO:0042026 15 6 0,000 0,03099195 0,10878354 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,03099195 0,10862747 ! opsonization GO:0008228 8 6 0,000 0,03099195 0,10847184 ! mating behavior GO:0007617 7 6 0,000 0,03099195 0,10831666 ! erythrocyte maturation GO:0043249 8 6 0,000 0,03099195 0,10816192 ! embryonic hemopoiesis GO:0035162 16 6 0,000 0,03099195 0,10800762 ! protein amino acid dealkylation GO:0008214 15 6 0,000 0,03099195 0,10785377 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 0,03099195 0,10770035 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 0,03099195 0,10754736 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,03099195 0,10739481 ! response to interferon-gamma GO:0034341 16 6 0,000 0,03099195 0,1072427 ! toxin metabolic process GO:0009404 11 6 0,000 0,03099195 0,10709101 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,03099195 0,10693975 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 0,03099195 0,10678892 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 0,03099195 0,10663851 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 0,03099195 0,10648853 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 13 6 0,000 0,03099195 0,10633897 ! cGMP-mediated signaling GO:0019934 14 6 0,000 0,03099195 0,10618982 ! dorsal spinal cord development GO:0021516 10 6 0,000 0,03099195 0,1060411 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,03099195 0,10589279 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 0,03099195 0,10574489 ! thymic T cell selection GO:0045061 16 6 0,000 0,03099195 0,10559741 ! sphingoid catabolic process GO:0046521 8 6 0,000 0,03099195 0,10545034 ! protein lipoylation GO:0009249 10 6 0,000 0,03099195 0,10530368 ! transepithelial chloride transport GO:0030321 12 6 0,000 0,03099195 0,10515742 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 0,03099195 0,10501157 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,03099195 0,10486613 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 0,03099195 0,10472108 ! glutamate catabolic process GO:0006538 12 6 0,000 0,03099195 0,10457644 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 0,03099195 0,1044322 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,03099195 0,10428835 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 0,03099195 0,1041449 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,03099195 0,10400184 ! hyperosmotic response GO:0006972 10 6 0,000 0,03099195 0,10385918 ! L-serine biosynthetic process GO:0006564 7 6 0,000 0,03099195 0,10371691 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 0,03099195 0,10357502 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 0,03099195 0,10343353 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,03099195 0,10329242 ! urea metabolic process GO:0019627 7 6 0,000 0,03099195 0,10315169 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,03099195 0,10301135 ! neutrophil activation GO:0042119 7 6 0,000 0,03099195 0,10287139 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,03099195 0,10273181 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 0,03099195 0,10259261 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,03099195 0,10245378 ! paraxial mesoderm development GO:0048339 16 6 0,000 0,03099195 0,10231533 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 0,03099195 0,10217725 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,03099195 0,10203955 ! neuron apoptosis GO:0051402 15 6 0,000 0,03099195 0,10190221 ! T cell mediated immunity GO:0002456 17 6 0,000 0,03099195 0,10176525 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,03099195 0,10162865 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 0,03099195 0,10149242 ! carnitine transport GO:0015879 10 6 0,000 0,03099195 0,10135655 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,03099195 0,10122105 ! positive regulation of exocytosis GO:0045921 11 6 0,000 0,03099195 0,10108591 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 0,03099195 0,10095112 ! early endosome to late endosome transport GO:0045022 16 6 0,000 0,03099195 0,1008167 ! 5S class rRNA transcription GO:0042791 13 6 0,000 0,03099195 0,10068264 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,03099195 0,10054893 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 0,03099195 0,10041557 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 0,03099195 0,10028257 ! sodium ion homeostasis GO:0055078 12 6 0,000 0,03099195 0,10014992 ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 0,03099195 0,10001763 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,03099195 0,09988568 GO:0045686|negative regulation of glial cell differentiation, ! response to UV-C GO:0010225 14 6 0,000 0,03099195 0,09975408 ! astrocyte development GO:0014002 16 6 0,000 0,03099195 0,09962282 ! protein targeting to lysosome GO:0006622 12 6 0,000 0,03099195 0,09949191 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,03099195 0,09936134 ! interaction with symbiont GO:0051702 14 6 0,000 0,03099195 0,09923112 ! regulation of dendrite development GO:0050773 16 6 0,000 0,03099195 0,09910123 ! peptidyl-arginine modification GO:0018195 13 6 0,000 0,03099195 0,09897169 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 0,03099195 0,09884248 ! response to copper ion GO:0046688 10 6 0,000 0,03099195 0,09871362 ! response to exogenous dsRNA GO:0043330 13 6 0,000 0,03099195 0,09858508 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 0,03099195 0,09845688 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,03099195 0,09832902 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,03099195 0,09820148 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 0,03099195 0,09807428 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,03099195 0,0979474 ! nucleoside catabolic process GO:0009164 10 6 0,000 0,03099195 0,09782086 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,03099195 0,09769464 ! Schwann cell development GO:0014044 15 6 0,000 0,03099195 0,09756874 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 0,03099195 0,09744317 ! response to pheromone GO:0019236 6 6 0,000 0,03099195 0,09731792 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 0,03099195 0,097193 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 0,03099195 0,09706839 ! subpallium development GO:0021544 15 6 0,000 0,03099195 0,0969441 ! neural tube patterning GO:0021532 8 6 0,000 0,03099195 0,09682013 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 0,03099195 0,09669648 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 0,03099195 0,09657314 ! maintenance of organ identity GO:0048496 9 6 0,000 0,03099195 0,09645012 ! G2 phase GO:0051319 16 6 0,000 0,03099195 0,09632741 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 0,03099195 0,09620501 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 0,03099195 0,09608292 ! oxygen homeostasis GO:0032364 10 6 0,000 0,03099195 0,09596114 ! establishment of planar polarity GO:0001736 7 6 0,000 0,03099195 0,09583967 ! regulation of mast cell activation GO:0033003 13 6 0,000 0,03099195 0,09571851 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,03099195 0,09559766 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 0,03099195 0,0954771 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,03099195 0,09535686 ! receptor internalization GO:0031623 11 6 0,000 0,03099195 0,09523691 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 0,03099195 0,09511727 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 0,03099195 0,09499792 ! neutrophil homeostasis GO:0001780 11 6 0,000 0,03099195 0,09487888 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,03099195 0,09476013 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 0,03099195 0,09464168 ! protein deubiquitination GO:0016579 16 6 0,000 0,03099195 0,09452352 ! negative regulation of neuroblast proliferation GO:0007406 25 6 0,000 0,03099195 0,09440566 ! protein destabilization GO:0031648 9 6 0,000 0,03099195 0,0942881 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 0,03099195 0,09417082 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,03099195 0,09405384 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 0,03099195 0,09393715 ! regulation of viral transcription GO:0046782 11 6 0,000 0,03099195 0,09382075 ! progesterone metabolic process GO:0042448 12 6 0,000 0,03099195 0,09370463 ! negative regulation of axon extension GO:0030517 24 6 0,000 0,03099195 0,0935888 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 0,03099195 0,09347326 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 0,03099195 0,09335801 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,03099195 0,09324303 ! determination of adult lifespan GO:0008340 17 6 0,000 0,03099195 0,09312834 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 0,03099195 0,09301394 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 0,03099195 0,09289981 ! neural plate development GO:0001840 9 6 0,000 0,03099195 0,09278596 ! catecholamine transport GO:0051937 9 6 0,000 0,03099195 0,09267239 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 0,03099195 0,0925591 ! sensory cilium assembly GO:0035058 10 6 0,000 0,03099195 0,09244608 ! organ or tissue specific immune response GO:0002251 8 6 0,000 0,03099195 0,09233335 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 0,03099195 0,09222088 ! maternal placenta development GO:0001893 12 6 0,000 0,03099195 0,09210869 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 0,03099195 0,09199677 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,03099195 0,09188513 ! negative regulation of B cell activation GO:0050869 14 6 0,000 0,03099195 0,09177375 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 0,03099195 0,09166264 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 0,03099195 0,09155181 ! positive regulation of coagulation GO:0050820 13 6 0,000 0,03099195 0,09144124 ! regulation of leukocyte proliferation GO:0070663 97 53 1,000 0,03152379 0,0928982 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! synapse organization GO:0050808 102 53 1,000 0,03152379 0,09278627 ! regulation of translational initiation GO:0006446 87 54 1,000 0,03262568 0,09591399 ! activation of phospholipase C activity GO:0007202 110 54 1,000 0,03262568 0,09579871 GO:0010863|positive regulation of phospholipase C activity, ! embryonic skeletal system development GO:0048706 101 54 1,000 0,03262568 0,09568371 ! covalent chromatin modification GO:0016569 115 54 1,000 0,03262568 0,09556898 ! regulation of cell shape GO:0008360 142 54 1,000 0,03262568 0,09545453 ! positive regulation of phospholipase activity GO:0010518 111 55 1,000 0,03374254 0,09860409 ! regulation of multicellular organism growth GO:0040014 90 55 1,000 0,03374254 0,09848629 ! negative regulation of cell motion GO:0051271 142 55 1,000 0,03374254 0,09836876 ! skeletal muscle fiber development GO:0048741 130 56 1,000 0,03487418 0,10154664 ! negative regulation of cytoskeleton organization GO:0051494 139 56 1,000 0,03487418 0,10142575 ! muscle fiber development GO:0048747 131 57 1,000 0,03602043 0,10463486 ! regulation of phospholipase activity GO:0010517 113 57 1,000 0,03602043 0,10451059 ! heart morphogenesis GO:0003007 105 57 1,000 0,03602043 0,10438661 ! tRNA transcription GO:0009304 17 7 0,000 0,03606358 0,10438783 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 0,03606358 0,10426429 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 0,03606358 0,10414105 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,03606358 0,1040181 ! regulation of helicase activity GO:0051095 16 7 0,000 0,03606358 0,10389544 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 0,03606358 0,10377306 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,03606358 0,10365098 ! sleep GO:0030431 16 7 0,000 0,03606358 0,10352918 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,03606358 0,10340766 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 0,03606358 0,10328643 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,03606358 0,10316549 ! prostate gland development GO:0030850 14 7 0,000 0,03606358 0,10304483 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,03606358 0,10292445 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,03606358 0,10280435 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,03606358 0,10268453 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,03606358 0,10256499 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,03606358 0,10244573 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,03606358 0,10232675 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,03606358 0,10220804 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,03606358 0,1020896 ! SMAD protein complex assembly GO:0007183 13 7 0,000 0,03606358 0,10197145 ! glycolipid transport GO:0046836 11 7 0,000 0,03606358 0,10185356 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,03606358 0,10173595 GO:0051923|sulfation, ! neuron adhesion GO:0007158 14 7 0,000 0,03606358 0,1016186 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,03606358 0,10150153 ! establishment of tissue polarity GO:0007164 8 7 0,000 0,03606358 0,10138473 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 0,03606358 0,10126819 ! pericardium development GO:0060039 16 7 0,000 0,03606358 0,10115193 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 0,03606358 0,10103593 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 0,03606358 0,10092019 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 0,03606358 0,10080472 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 0,03606358 0,10068952 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,03606358 0,10057458 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,03606358 0,1004599 ! lipoprotein transport GO:0042953 14 7 0,000 0,03606358 0,10034548 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,03606358 0,10023132 ! rhythmic behavior GO:0007622 17 7 0,000 0,03606358 0,10011742 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 0,03606358 0,10000378 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 0,03606358 0,0998904 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,03606358 0,09977727 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 0,03606358 0,0996644 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,03606358 0,09955178 ! regulation of odontogenesis GO:0042481 14 7 0,000 0,03606358 0,09943942 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,03606358 0,09932732 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 0,03606358 0,09921546 ! mechanosensory behavior GO:0007638 16 7 0,000 0,03606358 0,09910386 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 0,03606358 0,0989925 ! positive regulation of isotype switching GO:0045830 17 7 0,000 0,03606358 0,0988814 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 0,03606358 0,09877055 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,03606358 0,09865994 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,03606358 0,09854959 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,03606358 0,09843947 ! spinal cord patterning GO:0021511 14 7 0,000 0,03606358 0,09832961 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 0,03606358 0,09821999 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,03606358 0,09811061 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 0,03606358 0,09800148 ! adrenal gland development GO:0030325 17 7 0,000 0,03606358 0,09789259 ! cysteine metabolic process GO:0006534 13 7 0,000 0,03606358 0,09778394 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 0,03606358 0,09767553 ! ovulation GO:0030728 10 7 0,000 0,03606358 0,09756736 ! adenohypophysis development GO:0021984 11 7 0,000 0,03606358 0,09745943 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 0,03606358 0,09735174 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 0,03606358 0,09724429 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 0,03606358 0,09713708 ! microtubule nucleation GO:0007020 21 7 0,000 0,03606358 0,0970301 ! proline biosynthetic process GO:0006561 10 7 0,000 0,03606358 0,09692335 ! tryptophan metabolic process GO:0006568 11 7 0,000 0,03606358 0,09681685 ! thyroid hormone generation GO:0006590 13 7 0,000 0,03606358 0,09671057 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 0,03606358 0,09660453 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,03606358 0,09649872 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,03606358 0,09639314 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,03606358 0,09628779 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,03606358 0,09618267 ! galactose metabolic process GO:0006012 13 7 0,000 0,03606358 0,09607779 ! vesicle fusion GO:0006906 20 7 0,000 0,03606358 0,09597313 ! response to dietary excess GO:0002021 8 7 0,000 0,03606358 0,09586869 ! intracellular pH reduction GO:0051452 13 7 0,000 0,03606358 0,09576449 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,03606358 0,09566051 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 0,03606358 0,09555676 ! organ growth GO:0035265 15 7 0,000 0,03606358 0,09545323 ! nucleoside transport GO:0015858 11 7 0,000 0,03606358 0,09534992 ! nucleoside salvage GO:0043174 11 7 0,000 0,03606358 0,09524684 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 0,03606358 0,09514398 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,03606358 0,09504135 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 0,03606358 0,09493893 ! parturition GO:0007567 16 7 0,000 0,03606358 0,09483674 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 0,03606358 0,09473476 ! rRNA modification GO:0000154 14 7 0,000 0,03606358 0,09463301 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,03606358 0,09453147 ! spindle checkpoint GO:0031577 16 7 0,000 0,03606358 0,09443015 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,03606358 0,09432905 ! monocyte differentiation GO:0030224 16 7 0,000 0,03606358 0,09422816 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,03606358 0,09412749 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,03606358 0,09402703 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 0,03606358 0,09392679 ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,03606358 0,09382676 ! fibrinolysis GO:0042730 11 7 0,000 0,03606358 0,09372695 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,03606358 0,09362734 ! eating behavior GO:0042755 8 7 0,000 0,03606358 0,09352795 ! B cell lineage commitment GO:0002326 21 7 0,000 0,03606358 0,09342877 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,03606358 0,0933298 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 0,03606358 0,09323104 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,03606358 0,09313248 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 0,03606358 0,09303414 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,03606358 0,092936 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 0,03606358 0,09283807 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 0,03606358 0,09274035 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 0,03606358 0,09264283 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,03606358 0,09254551 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 0,03606358 0,0924484 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,03606358 0,0923515 ! histone ubiquitination GO:0016574 9 7 0,000 0,03606358 0,09225479 ! regulation of meiosis GO:0040020 12 7 0,000 0,03606358 0,09215829 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 0,03606358 0,09206199 ! T cell lineage commitment GO:0002360 16 7 0,000 0,03606358 0,0919659 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 0,03606358 0,09187 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,03606358 0,0917743 ! membrane to membrane docking GO:0022614 14 7 0,000 0,03606358 0,0916788 ! transcription termination GO:0006353 14 7 0,000 0,03606358 0,0915835 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,03606358 0,0914884 ! anaphase GO:0051322 18 7 0,000 0,03606358 0,09139349 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 0,03606358 0,09129879 ! axonal fasciculation GO:0007413 19 7 0,000 0,03606358 0,09120427 ! negative regulation of nuclear division GO:0051784 15 7 0,000 0,03606358 0,09110996 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 0,03606358 0,09101584 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,03606358 0,09092191 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 0,03606358 0,09082817 ! diuresis GO:0030146 12 7 0,000 0,03606358 0,09073463 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,03606358 0,09064128 ! thiamin metabolic process GO:0006772 7 7 0,000 0,03606358 0,09054813 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,03606358 0,09045516 ! antibiotic transport GO:0042891 9 7 0,000 0,03606358 0,09036239 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,03606358 0,0902698 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 0,03606358 0,09017741 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 0,03606358 0,0900852 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,03606358 0,08999319 ! melanin biosynthetic process GO:0042438 10 7 0,000 0,03606358 0,08990136 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 0,03606358 0,08980971 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,03606358 0,08971826 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,03606358 0,08962699 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 0,03606358 0,0895359 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,03606358 0,089445 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 0,03606358 0,08935429 ! endosome to lysosome transport GO:0008333 12 7 0,000 0,03606358 0,08926376 ! protein modification by small protein removal GO:0070646 19 7 0,000 0,03606358 0,08917341 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 0,03606358 0,08908324 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,03606358 0,08899326 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 0,03606358 0,08890346 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,03606358 0,08881384 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,03606358 0,0887244 ! muscle adaptation GO:0043500 13 7 0,000 0,03606358 0,08863514 ! embryonic heart tube development GO:0035050 14 7 0,000 0,03606358 0,08854606 ! retina homeostasis GO:0001895 12 7 0,000 0,03606358 0,08845716 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 0,03606358 0,08836843 ! protein amino acid prenylation GO:0018346 19 7 0,000 0,03606358 0,08827989 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 0,03606358 0,08819152 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 0,03606358 0,08810333 ! positive regulation of organelle organization GO:0010638 108 58 1,000 0,0371811 0,09074268 ! positive regulation of lipase activity GO:0060193 115 58 1,000 0,0371811 0,09065212 ! nuclear export GO:0051168 110 59 1,000 0,038356 0,09342345 ! establishment of organelle localization GO:0051656 122 59 1,000 0,038356 0,0933304 ! lipid modification GO:0030258 112 60 1,000 0,03954497 0,09612772 ! kidney development GO:0001822 133 60 1,000 0,03954497 0,09603217 ! camera-type eye development GO:0043010 126 61 1,000 0,04074782 0,09885493 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,04110881 0,09963176 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,04110881 0,09953302 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 0,04110881 0,09943447 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,04110881 0,09933612 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,04110881 0,09923796 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,04110881 0,09913999 ! male meiosis GO:0007140 9 8 0,000 0,04110881 0,09904222 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,04110881 0,09894464 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,04110881 0,09884726 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,04110881 0,09875006 ! meiotic prophase I GO:0007128 14 8 0,000 0,04110881 0,09865306 ! response to zinc ion GO:0010043 12 8 0,000 0,04110881 0,09855625 ! regulation of lipid kinase activity GO:0043550 17 8 0,000 0,04110881 0,09845962 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,04110881 0,09836319 ! oligopeptide transport GO:0006857 16 8 0,000 0,04110881 0,09826694 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,04110881 0,09817088 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,04110881 0,09807501 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,04110881 0,09797933 ! signal peptide processing GO:0006465 12 8 0,000 0,04110881 0,09788383 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,04110881 0,09778852 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,04110881 0,0976934 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,04110881 0,09759846 ! succinate metabolic process GO:0006105 17 8 0,000 0,04110881 0,0975037 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,04110881 0,09740913 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,04110881 0,09731474 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,04110881 0,09722054 ! estrogen metabolic process GO:0008210 17 8 0,000 0,04110881 0,09712651 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,04110881 0,09703267 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,04110881 0,09693901 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,04110881 0,09684553 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,04110881 0,09675223 ! reflex GO:0060004 17 8 0,000 0,04110881 0,09665911 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,04110881 0,09656617 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,04110881 0,0964734 ! hemoglobin metabolic process GO:0020027 14 8 0,000 0,04110881 0,09638082 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,04110881 0,09628841 ! pigment granule organization GO:0048753 17 8 0,000 0,04110881 0,09619618 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,04110881 0,09610413 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,04110881 0,09601225 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,04110881 0,09592055 ! astrocyte differentiation GO:0048708 19 8 0,000 0,04110881 0,09582902 ! histidine catabolic process GO:0006548 10 8 0,000 0,04110881 0,09573767 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,04110881 0,09564649 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,04110881 0,09555548 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,04110881 0,09546465 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,04110881 0,09537399 ! regulation of pigmentation during development GO:0048070 25 8 0,000 0,04110881 0,09528351 ! melanin metabolic process GO:0006582 17 8 0,000 0,04110881 0,09519319 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,04110881 0,09510304 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,04110881 0,09501307 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,04110881 0,09492327 ! macrophage activation GO:0042116 13 8 0,000 0,04110881 0,09483363 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,04110881 0,09474416 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,04110881 0,09465487 ! positive regulation of insulin secretion GO:0032024 17 8 0,000 0,04110881 0,09456574 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,04110881 0,09447678 ! purine salvage GO:0043101 12 8 0,000 0,04110881 0,09438798 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,04110881 0,09429936 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,04110881 0,0942109 ! osteoblast development GO:0002076 17 8 0,000 0,04110881 0,0941226 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,04110881 0,09403447 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,04110881 0,09394651 ! Schwann cell differentiation GO:0014037 21 8 0,000 0,04110881 0,09385871 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,04110881 0,09377107 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,04110881 0,0936836 ! response to UV-B GO:0010224 17 8 0,000 0,04110881 0,09359629 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,04110881 0,09350914 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,04110881 0,09342215 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,04110881 0,09333533 ! cellular extravasation GO:0045123 13 8 0,000 0,04110881 0,09324867 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,04110881 0,09316217 ! response to antibiotic GO:0046677 11 8 0,000 0,04110881 0,09307582 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,04110881 0,09298964 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,04110881 0,09290362 ! DNA topological change GO:0006265 12 8 0,000 0,04110881 0,09281776 ! response to tropane GO:0014073 15 8 0,000 0,04110881 0,09273205 GO:0042220|response to cocaine, ! melanosome transport GO:0032402 13 8 0,000 0,04110881 0,09264651 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,04110881 0,09256112 ! mast cell activation GO:0045576 14 8 0,000 0,04110881 0,09247589 ! multicellular organismal aging GO:0010259 20 8 0,000 0,04110881 0,09239081 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 0,04110881 0,0923059 ! gas homeostasis GO:0033483 14 8 0,000 0,04110881 0,09222113 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,04110881 0,09213653 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,04110881 0,09205208 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,04110881 0,09196778 ! nucleosome disassembly GO:0006337 14 8 0,000 0,04110881 0,09188364 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,04110881 0,09179965 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 0,04110881 0,09171581 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,04110881 0,09163213 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,04110881 0,0915486 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,04110881 0,09146522 ! intracellular lipid transport GO:0032365 16 8 0,000 0,04110881 0,091382 ! response to tumor cell GO:0002347 16 8 0,000 0,04110881 0,09129892 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,04110881 0,091216 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,04110881 0,09113323 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,04110881 0,0910506 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 0,04110881 0,09096813 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,04110881 0,09088581 ! hormone catabolic process GO:0042447 17 8 0,000 0,04110881 0,09080363 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,04110881 0,0907216 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,04110881 0,09063972 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,04110881 0,09055799 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,04110881 0,09047641 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,04110881 0,09039497 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,04110881 0,09031368 ! adult feeding behavior GO:0008343 10 8 0,000 0,04110881 0,09023254 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,04110881 0,09015154 ! ATP catabolic process GO:0006200 11 8 0,000 0,04110881 0,09007069 ! blastocyst growth GO:0001832 19 8 0,000 0,04110881 0,08998998 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,04110881 0,08990941 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,04110881 0,08982899 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,04110881 0,08974872 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,04110881 0,08966858 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,04110881 0,08958859 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,04110881 0,08950875 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,04110881 0,08942904 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,04110881 0,08934948 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,04110881 0,08927006 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 0,04110881 0,08919078 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,04110881 0,08911164 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 0,04110881 0,08903264 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,04110881 0,08895378 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,04110881 0,08887506 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 0,04110881 0,08879648 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 0,04110881 0,08871803 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,04110881 0,08863973 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 0,04110881 0,08856156 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 0,04110881 0,08848354 ! viral reproductive process GO:0022415 132 62 1,000 0,04196437 0,09024556 ! DNA damage response, signal transduction GO:0042770 136 62 1,000 0,04196437 0,09016619 ! regulation of mitosis GO:0007088 112 63 1,000 0,04319445 0,09272764 GO:0051783|regulation of nuclear division, ! skeletal system morphogenesis GO:0048705 118 63 1,000 0,04319445 0,09264623 ! integrin-mediated signaling pathway GO:0007229 160 64 1,000 0,0444379 0,09522964 ! axon extension GO:0048675 16 9 0,000 0,04612777 0,09876436 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,04612777 0,09867788 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 0,04612777 0,09859154 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,04612777 0,09850536 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,04612777 0,09841933 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,04612777 0,09833345 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,04612777 0,09824772 ! reproductive behavior GO:0019098 22 9 0,000 0,04612777 0,09816214 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,04612777 0,0980767 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 0,04612777 0,09799142 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 0,04612777 0,09790628 ! UTP metabolic process GO:0046051 10 9 0,000 0,04612777 0,0978213 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,04612777 0,09773646 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,04612777 0,09765176 ! artery development GO:0060840 25 9 0,000 0,04612777 0,09756722 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,04612777 0,09748281 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,04612777 0,09739856 ! equilibrioception GO:0050957 20 9 0,000 0,04612777 0,09731445 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,04612777 0,09723049 ! chemosensory behavior GO:0007635 21 9 0,000 0,04612777 0,09714667 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,04612777 0,09706299 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,04612777 0,09697946 ! leukocyte degranulation GO:0043299 16 9 0,000 0,04612777 0,09689607 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,04612777 0,09681283 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,04612777 0,09672973 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,04612777 0,09664677 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,04612777 0,09656395 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,04612777 0,09648128 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,04612777 0,09639875 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,04612777 0,09631635 ! protein targeting to ER GO:0045047 25 9 0,000 0,04612777 0,0962341 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,04612777 0,09615199 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 0,04612777 0,09607002 ! T cell selection GO:0045058 27 9 0,000 0,04612777 0,09598819 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,04612777 0,0959065 ! glycine catabolic process GO:0006546 15 9 0,000 0,04612777 0,09582494 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,04612777 0,09574353 ! endosome organization GO:0007032 20 9 0,000 0,04612777 0,09566225 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,04612777 0,09558111 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,04612777 0,09550011 ! mannose metabolic process GO:0006013 13 9 0,000 0,04612777 0,09541925 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,04612777 0,09533852 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,04612777 0,09525793 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 0,04612777 0,09517748 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,04612777 0,09509716 ! receptor clustering GO:0043113 20 9 0,000 0,04612777 0,09501698 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,04612777 0,09493693 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,04612777 0,09485702 ! retinol metabolic process GO:0042572 20 9 0,000 0,04612777 0,09477724 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,04612777 0,09469759 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,04612777 0,09461808 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,04612777 0,0945387 ! macrophage differentiation GO:0030225 15 9 0,000 0,04612777 0,09445946 ! oligodendrocyte development GO:0014003 11 9 0,000 0,04612777 0,09438035 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 0,04612777 0,09430137 ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,04612777 0,09422252 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,04612777 0,0941438 ! response to amine stimulus GO:0014075 13 9 0,000 0,04612777 0,09406522 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,04612777 0,09398677 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,04612777 0,09390844 ! erythrocyte development GO:0048821 17 9 0,000 0,04612777 0,09383025 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,04612777 0,09375219 ! renal water homeostasis GO:0003091 15 9 0,000 0,04612777 0,09367426 ! postreplication repair GO:0006301 25 9 0,000 0,04612777 0,09359646 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,04612777 0,09351878 ! icosanoid secretion GO:0032309 15 9 0,000 0,04612777 0,09344124 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,04612777 0,09336382 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,04612777 0,09328653 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,04612777 0,09320937 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,04612777 0,09313234 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,04612777 0,09305544 ! sterol catabolic process GO:0016127 14 9 0,000 0,04612777 0,09297866 GO:0006707|cholesterol catabolic process, ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,04612777 0,09290201 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,04612777 0,09282548 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,04612777 0,09274908 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 0,04612777 0,09267281 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,04612777 0,09259666 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 0,04612777 0,09252064 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,04612777 0,09244474 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,04612777 0,09236896 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,04612777 0,09229331 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,04612777 0,09221779 ! purine base metabolic process GO:0006144 25 9 0,000 0,04612777 0,09214238 ! pigment granule transport GO:0051904 17 9 0,000 0,04612777 0,0920671 ! regulation of telomere maintenance GO:0032204 17 9 0,000 0,04612777 0,09199195 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,04612777 0,09191691 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,04612777 0,091842 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,04612777 0,09176721 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,04612777 0,09169254 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,04612777 0,09161799 ! mitochondrion localization GO:0051646 18 9 0,000 0,04612777 0,09154357 ! gonad development GO:0008406 115 66 1,000 0,04696417 0,09312782 ! activation of MAPK activity GO:0000187 124 67 1,000 0,04824666 0,09559335 ! myeloid cell differentiation GO:0030099 126 67 1,000 0,04824666 0,09551588 ! positive regulation of T cell activation GO:0050870 124 68 1,000 0,04954184 0,09800057 ! viral reproduction GO:0016032 142 68 1,000 0,04954184 0,09792128 ! regulation of lipase activity GO:0060191 137 68 1,000 0,04954184 0,09784212 ! adaptive immune response GO:0002250 126 68 1,000 0,04954184 0,09776309 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! cell projection assembly GO:0030031 138 68 1,000 0,04954184 0,09768418 ! developmental maturation GO:0021700 128 69 1,000 0,05084952 0,10018176 ! urogenital system development GO:0001655 149 69 1,000 0,05084952 0,10010103 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,0511206 0,10055364 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 0,000 0,0511206 0,10047274 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,0511206 0,10039198 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,0511206 0,10031134 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,0511206 0,10023083 ! associative learning GO:0008306 21 10 0,000 0,0511206 0,10015046 ! positive regulation of B cell proliferation GO:0030890 18 10 0,000 0,0511206 0,10007021 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,0511206 0,09999009 ! phosphate transport GO:0006817 24 10 0,000 0,0511206 0,0999101 ! cell volume homeostasis GO:0006884 17 10 0,000 0,0511206 0,09983023 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,0511206 0,09975049 ! CTP metabolic process GO:0046036 11 10 0,000 0,0511206 0,09967089 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 0,0511206 0,0995914 ! GTP metabolic process GO:0046039 11 10 0,000 0,0511206 0,09951205 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,0511206 0,09943282 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,0511206 0,09935371 ! social behavior GO:0035176 29 10 0,000 0,0511206 0,09927474 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,0511206 0,09919588 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,0511206 0,09911716 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,0511206 0,09903856 ! androgen metabolic process GO:0008209 17 10 0,000 0,0511206 0,09896008 ! phospholipid efflux GO:0033700 19 10 0,000 0,0511206 0,09888173 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,0511206 0,0988035 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,0511206 0,09872539 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,0511206 0,09864741 ! pathogenesis GO:0009405 17 10 0,000 0,0511206 0,09856955 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,0511206 0,09849181 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 0,0511206 0,0984142 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,0511206 0,09833671 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,0511206 0,09825934 ! endoderm development GO:0007492 18 10 0,000 0,0511206 0,09818209 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,0511206 0,09810496 ! arginine catabolic process GO:0006527 17 10 0,000 0,0511206 0,09802796 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,0511206 0,09795107 ! proline metabolic process GO:0006560 13 10 0,000 0,0511206 0,09787431 ! phosphagen metabolic process GO:0006599 17 10 0,000 0,0511206 0,09779767 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,0511206 0,09772114 ! V(D)J recombination GO:0033151 34 10 0,000 0,0511206 0,09764474 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,0511206 0,09756845 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,0511206 0,09749229 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,0511206 0,09741624 ! B cell proliferation GO:0042100 19 10 0,000 0,0511206 0,09734031 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,0511206 0,0972645 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,0511206 0,09718881 ! multicellular organism growth GO:0035264 19 10 0,000 0,0511206 0,09711323 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,0511206 0,09703778 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,0511206 0,09696244 ! ruffle organization GO:0031529 17 10 0,000 0,0511206 0,09688721 ! epithelial cell development GO:0002064 21 10 0,000 0,0511206 0,09681211 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,0511206 0,09673712 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,0511206 0,09666224 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,0511206 0,09658749 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,0511206 0,09651284 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,0511206 0,09643832 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 13 10 0,000 0,0511206 0,0963639 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,0511206 0,09628961 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,0511206 0,09621542 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,0511206 0,09614135 ! segment specification GO:0007379 15 10 0,000 0,0511206 0,0960674 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,0511206 0,09599356 ! blastoderm segmentation GO:0007350 19 10 0,000 0,0511206 0,09591983 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,0511206 0,09584622 ! response to dsRNA GO:0043331 23 10 0,000 0,0511206 0,09577271 ! DNA ligation GO:0006266 18 10 0,000 0,0511206 0,09569932 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,0511206 0,09562605 ! melanosome localization GO:0032400 16 10 0,000 0,0511206 0,09555288 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,0511206 0,09547983 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,0511206 0,09540689 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,0511206 0,09533406 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,0511206 0,09526134 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,0511206 0,09518873 ! induction of an organ GO:0001759 17 10 0,000 0,0511206 0,09511624 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,0511206 0,09504385 GO:0002263|cell activation during immune response, ! protein sumoylation GO:0016925 17 10 0,000 0,0511206 0,09497157 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,0511206 0,09489941 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,0511206 0,09482735 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,0511206 0,0947554 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,0511206 0,09468356 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,0511206 0,09461183 ! salivary gland development GO:0007431 28 10 0,000 0,0511206 0,09454021 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,0511206 0,0944687 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,0511206 0,09439729 ! midbrain development GO:0030901 14 10 0,000 0,0511206 0,094326 ! musculoskeletal movement GO:0050881 16 10 0,000 0,0511206 0,09425481 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,0511206 0,09418372 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,0511206 0,09411275 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,0511206 0,09404188 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,0511206 0,09397112 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,0511206 0,09390047 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,0511206 0,09382992 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,0511206 0,09375947 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,0511206 0,09368914 ! detection of calcium ion GO:0005513 24 10 0,000 0,0511206 0,0936189 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,0511206 0,09354878 ! blastocyst formation GO:0001825 18 10 0,000 0,0511206 0,09347876 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,0511206 0,09340884 ! cerebellar cortex development GO:0021695 16 10 0,000 0,0511206 0,09333903 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,0511206 0,09326932 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,0511206 0,09319972 ! response to nicotine GO:0035094 20 10 0,000 0,0511206 0,09313022 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,0511206 0,09306082 ! cell cycle checkpoint GO:0000075 145 71 1,000 0,05350177 0,09732303 ! carbohydrate transport GO:0008643 114 72 1,000 0,05484601 0,09969405 ! negative regulation of muscle development GO:0048635 27 11 0,000 0,05608743 0,1018748 ! respiratory burst GO:0045730 17 11 0,000 0,05608743 0,10179911 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,05608743 0,10172353 ! neuron fate specification GO:0048665 18 11 0,000 0,05608743 0,10164807 ! telencephalon cell migration GO:0022029 23 11 0,000 0,05608743 0,10157272 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,05608743 0,10149748 ! thyroid gland development GO:0030878 26 11 0,000 0,05608743 0,10142235 ! synapsis GO:0007129 14 11 0,000 0,05608743 0,10134734 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,05608743 0,10127243 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,05608743 0,10119764 ! response to pain GO:0048265 27 11 0,000 0,05608743 0,10112295 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,05608743 0,10104838 ! keratinocyte proliferation GO:0043616 19 11 0,000 0,05608743 0,10097391 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 0,000 0,05608743 0,10089956 GO:0010812|negative regulation of cell-substrate adhesion, ! bone resorption GO:0045453 16 11 0,000 0,05608743 0,10082531 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,05608743 0,10075118 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,05608743 0,10067715 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,05608743 0,10060323 ! melanocyte differentiation GO:0030318 20 11 0,000 0,05608743 0,10052942 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,05608743 0,10045572 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,05608743 0,10038212 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,05608743 0,10030864 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,05608743 0,10023526 ! regulation of intracellular pH GO:0051453 21 11 0,000 0,05608743 0,10016199 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,05608743 0,10008882 ! UV protection GO:0009650 20 11 0,000 0,05608743 0,10001577 ! adult heart development GO:0007512 16 11 0,000 0,05608743 0,09994282 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,05608743 0,09986997 ! macroautophagy GO:0016236 19 11 0,000 0,05608743 0,09979723 ! temperature homeostasis GO:0001659 18 11 0,000 0,05608743 0,0997246 ! behavioral fear response GO:0001662 27 11 0,000 0,05608743 0,09965207 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,05608743 0,09957965 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,05608743 0,09950734 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 0,05608743 0,09943512 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,05608743 0,09936302 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,05608743 0,09929101 ! regulation of organ growth GO:0046620 14 11 0,000 0,05608743 0,09921912 ! pigment granule localization GO:0051875 20 11 0,000 0,05608743 0,09914732 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,05608743 0,09907563 ! vasoconstriction GO:0042310 20 11 0,000 0,05608743 0,09900405 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,05608743 0,09893256 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,05608743 0,09886118 ! embryonic axis specification GO:0000578 19 11 0,000 0,05608743 0,09878991 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,05608743 0,09871873 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,05608743 0,09864766 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,05608743 0,09857669 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,05608743 0,09850582 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,05608743 0,09843506 GO:0006305|DNA alkylation, ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,05608743 0,09836439 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,05608743 0,09829383 ! prophase GO:0051324 17 11 0,000 0,05608743 0,09822337 ! neuroblast proliferation GO:0007405 25 11 0,000 0,05608743 0,09815301 ! nucleosome positioning GO:0016584 15 11 0,000 0,05608743 0,09808275 ! regulation of isotype switching GO:0045191 24 11 0,000 0,05608743 0,09801259 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,05608743 0,09794253 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,05608743 0,09787257 ! apical protein localization GO:0045176 18 11 0,000 0,05608743 0,09780271 ! acid secretion GO:0046717 20 11 0,000 0,05608743 0,09773295 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,05608743 0,09766329 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,05608743 0,09759373 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,05608743 0,09752427 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,05608743 0,09745491 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 0,05608743 0,09738564 ! cholesterol efflux GO:0033344 21 11 0,000 0,05608743 0,09731648 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,05608743 0,09724741 ! oocyte development GO:0048599 20 11 0,000 0,05608743 0,09717844 ! germ cell migration GO:0008354 26 11 0,000 0,05608743 0,09710957 ! embryonic gut development GO:0048566 19 11 0,000 0,05608743 0,09704079 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,05608743 0,09697212 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,05608743 0,09690354 ! activation of innate immune response GO:0002218 16 11 0,000 0,05608743 0,09683505 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,05608743 0,09676667 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,05608743 0,09669838 ! lysogeny GO:0030069 22 11 0,000 0,05608743 0,09663018 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,05608743 0,09656209 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,05608743 0,09649408 ! sequestering of metal ion GO:0051238 15 11 0,000 0,05608743 0,09642618 ! nucleus localization GO:0051647 22 11 0,000 0,05608743 0,09635837 ! regulation of caspase activity GO:0043281 136 74 1,000 0,05756992 0,09883578 ! organelle localization GO:0051640 155 74 1,000 0,05756992 0,09876637 ! regulation of transcription factor activity GO:0051090 137 75 1,000 0,05894927 0,1010618 GO:0090046|regulation of transcription regulator activity, ! reproductive structure development GO:0048608 131 75 1,000 0,05894927 0,10099092 ! phosphoinositide-mediated signaling GO:0048015 141 75 1,000 0,05894927 0,10092015 ! eye development GO:0001654 155 75 1,000 0,05894927 0,10084948 ! axon guidance GO:0007411 162 75 1,000 0,05894927 0,10077891 ! lymphocyte differentiation GO:0030098 193 76 1,000 0,06034 0,10308436 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,06102841 0,10418757 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,06102841 0,10411481 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,06102841 0,10404215 ! regulation of B cell proliferation GO:0030888 22 12 0,000 0,06102841 0,1039696 ! mating GO:0007618 17 12 0,000 0,06102841 0,10389715 ! protein complex disassembly GO:0043241 28 12 0,000 0,06102841 0,1038248 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,06102841 0,10375255 ! regulation of cell projection assembly GO:0060491 33 12 0,000 0,06102841 0,10368039 ! hippocampus development GO:0021766 29 12 0,000 0,06102841 0,10360834 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,06102841 0,10353639 ! T cell proliferation GO:0042098 32 12 0,000 0,06102841 0,10346454 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,06102841 0,10339279 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,06102841 0,10332114 ! ventral spinal cord development GO:0021517 25 12 0,000 0,06102841 0,10324959 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,06102841 0,10317814 ! drug transport GO:0015893 16 12 0,000 0,06102841 0,10310678 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,06102841 0,10303553 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,06102841 0,10296437 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,06102841 0,10289331 ! polyamine metabolic process GO:0006595 18 12 0,000 0,06102841 0,10282235 ! focal adhesion formation GO:0048041 37 12 0,000 0,06102841 0,10275149 ! mitotic spindle organization GO:0007052 23 12 0,000 0,06102841 0,10268072 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,06102841 0,10261005 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,06102841 0,10253948 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,06102841 0,10246901 ! lipid digestion GO:0044241 21 12 0,000 0,06102841 0,10239863 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,06102841 0,10232835 ! entry into host cell GO:0030260 34 12 0,000 0,06102841 0,10225817 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,06102841 0,10218808 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,06102841 0,10211809 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,06102841 0,10204819 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,06102841 0,10197839 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,06102841 0,10190869 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,06102841 0,10183908 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,06102841 0,10176956 ! snRNA metabolic process GO:0016073 30 12 0,000 0,06102841 0,10170014 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,06102841 0,10163082 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,06102841 0,10156159 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,06102841 0,10149245 ! fucose catabolic process GO:0019317 25 12 0,000 0,06102841 0,10142341 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,06102841 0,10135446 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,06102841 0,1012856 ! zymogen activation GO:0031638 18 12 0,000 0,06102841 0,10121684 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,06102841 0,10114817 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,06102841 0,1010796 ! oocyte differentiation GO:0009994 21 12 0,000 0,06102841 0,10101112 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,06102841 0,10094273 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,06102841 0,10087443 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,06102841 0,10080623 ! defense response to fungus GO:0050832 15 12 0,000 0,06102841 0,10073811 ! developmental induction GO:0031128 22 12 0,000 0,06102841 0,10067009 GO:0045168|cell-cell signaling involved in cell fate specification, ! lamellipodium assembly GO:0030032 24 12 0,000 0,06102841 0,10060216 ! response to cold GO:0009409 17 12 0,000 0,06102841 0,10053433 ! establishment of cell polarity GO:0030010 21 12 0,000 0,06102841 0,10046658 ! regulation of synapse organization GO:0050807 18 12 0,000 0,06102841 0,10039893 ! phosphoinositide metabolic process GO:0030384 146 77 1,000 0,06174197 0,10150447 ! regulation of endopeptidase activity GO:0052548 141 77 1,000 0,06174197 0,10143621 ! positive regulation of lymphocyte activation GO:0051251 142 78 1,000 0,06315502 0,10368798 ! response to steroid hormone stimulus GO:0048545 147 79 1,000 0,06457899 0,10595465 ! regulation of synaptic transmission GO:0050804 159 79 1,000 0,06457899 0,10588354 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,06594366 0,10804854 ! cGMP metabolic process GO:0046068 18 13 0,000 0,06594366 0,10797612 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,06594366 0,1079038 ! regulation of chemokine production GO:0032642 18 13 0,000 0,06594366 0,10783157 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,06594366 0,10775944 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,06594366 0,10768741 ! peroxisomal transport GO:0043574 28 13 0,000 0,06594366 0,10761548 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,06594366 0,10754364 ! cartilage condensation GO:0001502 22 13 0,000 0,06594366 0,10747189 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,06594366 0,10740024 ! organelle fusion GO:0048284 36 13 0,000 0,06594366 0,10732869 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,06594366 0,10725723 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,06594366 0,10718587 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,06594366 0,10711461 ! endocrine pancreas development GO:0031018 25 13 0,000 0,06594366 0,10704343 ! positive regulation of cell growth GO:0030307 24 13 0,000 0,06594366 0,10697236 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,06594366 0,10690137 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,06594366 0,10683048 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,06594366 0,10675969 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,06594366 0,10668898 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,06594366 0,10661838 ! methionine metabolic process GO:0006555 31 13 0,000 0,06594366 0,10654786 ! plasma membrane organization GO:0007009 27 13 0,000 0,06594366 0,10647744 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,06594366 0,10640711 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,06594366 0,10633688 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,06594366 0,10626673 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,06594366 0,10619668 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! response to X-ray GO:0010165 28 13 0,000 0,06594366 0,10612672 ! cytokine metabolic process GO:0042107 24 13 0,000 0,06594366 0,10605686 ! cellular carbohydrate catabolic process GO:0044275 17 13 0,000 0,06594366 0,10598708 ! exocrine system development GO:0035272 34 13 0,000 0,06594366 0,1059174 ! asymmetric protein localization GO:0008105 24 13 0,000 0,06594366 0,10584781 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,06594366 0,10577831 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 0,06594366 0,1057089 ! L-glutamate transport GO:0015813 30 13 0,000 0,06594366 0,10563958 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,06594366 0,10557036 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,06594366 0,10550122 ! protein homotetramerization GO:0051289 24 13 0,000 0,06594366 0,10543218 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,06594366 0,10536322 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,06594366 0,10529436 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,06594366 0,10522558 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,06594366 0,1051569 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,06594366 0,1050883 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,06594366 0,1050198 ! histone methylation GO:0016571 29 13 0,000 0,06594366 0,10495138 ! chromatin silencing GO:0006342 29 13 0,000 0,06594366 0,10488305 ! gland morphogenesis GO:0022612 31 13 0,000 0,06594366 0,10481481 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,06594366 0,10474666 ! regulation of epidermis development GO:0045682 19 13 0,000 0,06594366 0,1046786 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,06594366 0,10461063 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,06594366 0,10454274 ! spleen development GO:0048536 24 13 0,000 0,06594366 0,10447495 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,06594366 0,10440724 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,06594366 0,10433962 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,06594366 0,10427208 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,06594366 0,10420464 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,06594366 0,10413728 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,06594366 0,10407 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,06594366 0,10400282 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,06594366 0,10393572 ! insulin secretion GO:0030073 24 13 0,000 0,06594366 0,10386871 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,06594366 0,10380178 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 0,06594366 0,10373494 ! acrosome reaction GO:0007340 19 13 0,000 0,06594366 0,10366819 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,06594366 0,10360152 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,06594366 0,10353494 ! development of primary sexual characteristics GO:0045137 143 80 1,000 0,06601374 0,10357839 ! meiosis GO:0007126 143 81 1,000 0,0674591 0,1057783 GO:0051327|M phase of meiotic cell cycle, ! regulation of peptidase activity GO:0052547 150 82 1,000 0,06891495 0,1079918 ! meiotic cell cycle GO:0051321 144 82 1,000 0,06891495 0,10792257 ! response to drug GO:0042493 149 83 1,000 0,07038112 0,11014802 ! inorganic anion transport GO:0015698 156 83 1,000 0,07038112 0,11007751 ! rRNA transcription GO:0009303 28 14 0,000 0,07083332 0,11071389 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,07083332 0,1106431 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 0,07083332 0,1105724 ! water transport GO:0006833 21 14 0,000 0,07083332 0,11050179 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,07083332 0,11043127 ! non-recombinational repair GO:0000726 29 14 0,000 0,07083332 0,11036084 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,07083332 0,11029051 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,07083332 0,11022026 ! hair follicle morphogenesis GO:0031069 27 14 0,000 0,07083332 0,1101501 ! RNA polyadenylation GO:0043631 32 14 0,000 0,07083332 0,11008003 ! palate development GO:0060021 32 14 0,000 0,07083332 0,11001005 ! regulated secretory pathway GO:0045055 24 14 0,000 0,07083332 0,10994016 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,07083332 0,10987035 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,07083332 0,10980064 ! arginine metabolic process GO:0006525 21 14 0,000 0,07083332 0,10973101 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,07083332 0,10966147 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,07083332 0,10959202 ! regulation of heart rate GO:0002027 25 14 0,000 0,07083332 0,10952266 ! fear response GO:0042596 34 14 0,000 0,07083332 0,10945339 ! organic alcohol transport GO:0015850 29 14 0,000 0,07083332 0,1093842 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,07083332 0,1093151 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 0,000 0,07083332 0,10924609 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,07083332 0,10917716 ! neutral amino acid transport GO:0015804 28 14 0,000 0,07083332 0,10910833 ! bone mineralization GO:0030282 18 14 0,000 0,07083332 0,10903957 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,07083332 0,10897091 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,07083332 0,10890233 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,07083332 0,10883384 ! regulation of cellular pH GO:0030641 27 14 0,000 0,07083332 0,10876543 ! ribosome assembly GO:0042255 18 14 0,000 0,07083332 0,10869711 ! cerebellum development GO:0021549 23 14 0,000 0,07083332 0,10862888 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,07083332 0,10856073 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,07083332 0,10849267 ! response to gamma radiation GO:0010332 30 14 0,000 0,07083332 0,10842469 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,07083332 0,1083568 ! NADP metabolic process GO:0006739 24 14 0,000 0,07083332 0,10828899 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,07083332 0,10822127 ! oxygen transport GO:0015671 22 14 0,000 0,07083332 0,10815363 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,07083332 0,10808607 ! male genitalia development GO:0030539 26 14 0,000 0,07083332 0,1080186 ! regulation of axon extension GO:0030516 43 14 0,000 0,07083332 0,10795122 ! release of cytochrome c from mitochondria GO:0001836 31 14 0,000 0,07083332 0,10788392 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,07083332 0,1078167 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 0,07083332 0,10774957 ! response to nutrient GO:0007584 135 84 1,000 0,07185746 0,10923944 ! digestion GO:0007586 130 84 1,000 0,07185746 0,10917151 ! regulation of neuron differentiation GO:0045664 187 85 1,000 0,07334385 0,11136048 ! regulation of transmission of nerve impulse GO:0051969 167 85 1,000 0,07334385 0,11129132 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,07569752 0,11479146 ! lactation GO:0007595 30 15 0,000 0,07569752 0,11472025 ! reproductive cellular process GO:0048610 22 15 0,000 0,07569752 0,11464913 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,07569752 0,11457809 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,07569752 0,11450715 ! superoxide anion generation GO:0042554 22 15 0,000 0,07569752 0,11443629 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,07569752 0,11436552 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,07569752 0,11429484 ! copper ion transport GO:0006825 22 15 0,000 0,07569752 0,11422424 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,07569752 0,11415373 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,07569752 0,11408331 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,07569752 0,11401297 ! sulfate transport GO:0008272 27 15 0,000 0,07569752 0,11394273 ! response to cAMP GO:0051591 25 15 0,000 0,07569752 0,11387256 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,07569752 0,11380249 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,07569752 0,1137325 ! response to hexose stimulus GO:0009746 25 15 0,000 0,07569752 0,1136626 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,07569752 0,11359278 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,07569752 0,11352305 ! vesicle coating GO:0006901 38 15 0,000 0,07569752 0,1134534 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 0,07569752 0,11338384 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 0,000 0,07569752 0,11331436 ! regulation of exocytosis GO:0017157 26 15 0,000 0,07569752 0,11324497 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,07569752 0,11317567 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,07569752 0,11310645 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,07569752 0,11303731 ! regulation of vasodilation GO:0042312 27 15 0,000 0,07569752 0,11296826 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,07569752 0,11289929 ! histone deacetylation GO:0016575 24 15 0,000 0,07569752 0,11283041 ! water homeostasis GO:0030104 28 15 0,000 0,07569752 0,11276161 ! cofactor transport GO:0051181 30 15 0,000 0,07569752 0,1126929 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,07569752 0,11262426 ! muscle maintenance GO:0046716 26 15 0,000 0,07569752 0,11255572 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,07569752 0,11248725 ! dopamine metabolic process GO:0042417 35 15 0,000 0,07569752 0,11241887 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,07569752 0,11235057 ! heme biosynthetic process GO:0006783 33 15 0,000 0,07569752 0,11228236 ! cell killing GO:0001906 32 15 0,000 0,07569752 0,11221423 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,07569752 0,11214618 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,07569752 0,11207821 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,07569752 0,11201032 ! actin filament polymerization GO:0030041 27 15 0,000 0,07569752 0,11194252 ! mitochondrion organization GO:0007005 159 87 1,000 0,07634614 0,11283341 ! regulation of DNA binding GO:0051101 167 89 1,000 0,07938686 0,1172564 ! regulation of neurological system process GO:0031644 175 89 1,000 0,07938686 0,11718555 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,08053639 0,11881063 ! positive regulation of cell size GO:0045793 29 16 0,000 0,08053639 0,11873893 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,08053639 0,11866731 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,08053639 0,11859578 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,08053639 0,11852434 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,08053639 0,11845298 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,08053639 0,11838171 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,08053639 0,11831053 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,08053639 0,11823943 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,08053639 0,11816841 ! startle response GO:0001964 28 16 0,000 0,08053639 0,11809748 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,08053639 0,11802664 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,08053639 0,11795588 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,08053639 0,1178852 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,08053639 0,11781461 ! protein polyubiquitination GO:0000209 41 16 0,000 0,08053639 0,11774411 ! glutamate metabolic process GO:0006536 25 16 0,000 0,08053639 0,11767369 ! pituitary gland development GO:0021983 30 16 0,000 0,08053639 0,11760335 ! response to osmotic stress GO:0006970 27 16 0,000 0,08053639 0,1175331 ! lysosomal transport GO:0007041 31 16 0,000 0,08053639 0,11746293 ! fructose metabolic process GO:0006000 25 16 0,000 0,08053639 0,11739284 ! L-amino acid transport GO:0015807 33 16 0,000 0,08053639 0,11732284 ! stem cell development GO:0048864 46 16 0,000 0,08053639 0,11725292 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,08053639 0,11718309 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,08053639 0,11711334 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,08053639 0,11704367 ! negative regulation of immune response GO:0050777 38 16 0,000 0,08053639 0,11697408 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,08053639 0,11690458 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,08053639 0,11683516 ! DNA replication initiation GO:0006270 28 16 0,000 0,08053639 0,11676582 ! neuron recognition GO:0008038 40 16 0,000 0,08053639 0,11669656 ! tissue regeneration GO:0042246 27 16 0,000 0,08053639 0,11662739 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,08053639 0,1165583 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,08053639 0,11648929 ! biomineral formation GO:0031214 22 16 0,000 0,08053639 0,11642036 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,08053639 0,11635151 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,08053639 0,11628275 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,08053639 0,11621406 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,08053639 0,11614546 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,08053639 0,11607694 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,08053639 0,11600849 ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,08053639 0,11594013 ! peptide hormone processing GO:0016486 27 16 0,000 0,08053639 0,11587185 ! gland development GO:0048732 220 91 1,000 0,08246488 0,11857663 ! regulation of cell adhesion GO:0030155 241 92 1,000 0,08401754 0,12073814 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,08535007 0,12258096 ! metencephalon development GO:0022037 32 17 0,000 0,08535007 0,12250894 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,08535007 0,122437 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,08535007 0,12236515 ! signal complex assembly GO:0007172 47 17 0,000 0,08535007 0,12229338 ! filopodium assembly GO:0046847 42 17 0,000 0,08535007 0,1222217 ! endothelial cell migration GO:0043542 31 17 0,000 0,08535007 0,1221501 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,08535007 0,12207858 ! glial cell development GO:0021782 28 17 0,000 0,08535007 0,12200715 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,08535007 0,1219358 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,08535007 0,12186453 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,08535007 0,12179335 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 0,000 0,08535007 0,12172225 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,08535007 0,12165123 ! myoblast differentiation GO:0045445 50 17 0,000 0,08535007 0,1215803 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,08535007 0,12150945 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,08535007 0,12143868 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,08535007 0,12136799 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,08535007 0,12129739 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,08535007 0,12122687 ! NAD metabolic process GO:0019674 33 17 0,000 0,08535007 0,12115643 ! membrane budding GO:0006900 42 17 0,000 0,08535007 0,12108607 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,08535007 0,12101579 ! regulation of protein binding GO:0043393 33 17 0,000 0,08535007 0,1209456 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,08535007 0,12087549 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,08535007 0,12080545 ! genitalia development GO:0048806 32 17 0,000 0,08535007 0,1207355 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 0,000 0,08535007 0,12066563 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,08535007 0,12059584 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,08535007 0,12052613 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,08535007 0,12045651 ! steroid catabolic process GO:0006706 34 17 0,000 0,08535007 0,12038696 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,08535007 0,12031749 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,08535007 0,1202481 ! gas transport GO:0015669 26 17 0,000 0,08535007 0,1201788 ! organic cation transport GO:0015695 32 17 0,000 0,08535007 0,12010957 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,08535007 0,12004042 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,08535007 0,11997135 ! regulation of cell morphogenesis GO:0022604 243 93 1,000 0,08557911 0,12022413 ! carbohydrate biosynthetic process GO:0016051 158 94 1,000 0,08714946 0,12235984 ! regulation of membrane potential GO:0042391 179 94 1,000 0,08714946 0,12228956 ! positive regulation of protein complex assembly GO:0031334 34 18 0,000 0,09013868 0,12641147 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,09013868 0,12633895 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,09013868 0,1262665 ! limbic system development GO:0021761 40 18 0,000 0,09013868 0,12619415 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,09013868 0,12612187 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,09013868 0,12604968 ! adult walking behavior GO:0007628 36 18 0,000 0,09013868 0,12597756 ! patterning of blood vessels GO:0001569 43 18 0,000 0,09013868 0,12590554 ! heart looping GO:0001947 34 18 0,000 0,09013868 0,12583359 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,09013868 0,12576173 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,09013868 0,12568994 ! centrosome cycle GO:0007098 26 18 0,000 0,09013868 0,12561824 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,09013868 0,12554663 ! epidermis morphogenesis GO:0048730 43 18 0,000 0,09013868 0,12547509 ! glycine metabolic process GO:0006544 30 18 0,000 0,09013868 0,12540363 ! glutamine metabolic process GO:0006541 29 18 0,000 0,09013868 0,12533226 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,09013868 0,12526097 ! DNA integration GO:0015074 32 18 0,000 0,09013868 0,12518976 ! negative regulation of protein catabolic process GO:0042177 42 18 0,000 0,09013868 0,12511863 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,09013868 0,12504758 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,09013868 0,12497661 ! neural crest cell migration GO:0001755 41 18 0,000 0,09013868 0,12490572 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,09013868 0,12483491 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,09013868 0,12476418 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,09013868 0,12469354 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,09013868 0,12462297 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,09013868 0,12455248 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,09013868 0,12448207 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,09013868 0,12441174 ! detection of bacterium GO:0016045 22 18 0,000 0,09013868 0,12434149 ! defense response to virus GO:0051607 43 18 0,000 0,09013868 0,12427132 ! microspike assembly GO:0030035 46 18 0,000 0,09013868 0,12420123 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,09013868 0,12413122 ! sex differentiation GO:0007548 171 96 1,000 0,09031597 0,1243053 ! leukocyte differentiation GO:0002521 232 98 1,000 0,09351602 0,12863718 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,09490235 0,1304707 ! positive regulation of translation GO:0045727 31 19 0,000 0,09490235 0,13039732 ! negative regulation of defense response GO:0031348 27 19 0,000 0,09490235 0,13032402 ! G1 phase of mitotic cell cycle GO:0000080 39 19 0,000 0,09490235 0,13025081 ! neuron maturation GO:0042551 46 19 0,000 0,09490235 0,13017767 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,09490235 0,13010462 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 0,09490235 0,13003165 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,09490235 0,12995876 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,09490235 0,12988596 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,09490235 0,12981323 ! inositol metabolic process GO:0006020 33 19 0,000 0,09490235 0,12974059 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,09490235 0,12966803 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,09490235 0,12959555 GO:0042744|hydrogen peroxide catabolic process, ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,09490235 0,12952315 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 0,000 0,09490235 0,12945083 ! cerebral cortex development GO:0021987 40 19 0,000 0,09490235 0,12937859 ! pigmentation during development GO:0048066 42 19 0,000 0,09490235 0,12930643 ! heme metabolic process GO:0042168 40 19 0,000 0,09490235 0,12923436 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,09490235 0,12916236 ! response to fungus GO:0009620 26 19 0,000 0,09490235 0,12909044 ! peptide cross-linking GO:0018149 39 19 0,000 0,09490235 0,12901861 ! heart process GO:0003015 32 19 0,000 0,09490235 0,12894685 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,09490235 0,12887517 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,09490235 0,12880357 ! visual learning GO:0008542 38 19 0,000 0,09490235 0,12873206 ! cellular pigmentation GO:0033059 37 19 0,000 0,09490235 0,12866062 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,09490235 0,12858926 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,09490235 0,12851798 ! vitamin transport GO:0051180 31 19 0,000 0,09490235 0,12844678 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,09490235 0,12837566 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,09490235 0,12830461 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,09490235 0,12823365 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,09490235 0,12816276 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,09490235 0,12809195 ! cilium assembly GO:0042384 38 19 0,000 0,09490235 0,12802122 ! peptide hormone secretion GO:0030072 32 19 0,000 0,09490235 0,12795057 ! protein secretion GO:0009306 45 20 0,000 0,09964121 0,13426557 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,09964121 0,13419155 ! positive regulation of ossification GO:0045778 50 20 0,000 0,09964121 0,13411762 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,09964121 0,13404377 ! skin development GO:0043588 42 20 0,000 0,09964121 0,13396999 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,09964121 0,1338963 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,09964121 0,13382269 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,09964121 0,13374916 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,09964121 0,13367572 ! forelimb morphogenesis GO:0035136 35 20 0,000 0,09964121 0,13360235 ! bile acid metabolic process GO:0008206 34 20 0,000 0,09964121 0,13352906 ! response to alkaloid GO:0043279 38 20 0,000 0,09964121 0,13345586 ! retinoid metabolic process GO:0001523 34 20 0,000 0,09964121 0,13338273 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 40 20 0,000 0,09964121 0,13330968 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,09964121 0,13323672 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,09964121 0,13316383 GO:0032392|DNA geometric change, ! actin filament bundle formation GO:0051017 47 20 0,000 0,09964121 0,13309102 ! body fluid secretion GO:0007589 33 20 0,000 0,09964121 0,13301829 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,09964121 0,13294565 ! peptide secretion GO:0002790 38 20 0,000 0,09964121 0,13287308 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,09964121 0,13280059 ! regulation of fatty acid metabolic process GO:0019217 45 20 0,000 0,09964121 0,13272818 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,09964121 0,13265585 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,09964121 0,13258359 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,09964121 0,13251142 ! cell-cell junction organization GO:0045216 43 20 0,000 0,09964121 0,13243933 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,09964121 0,13236731 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,09964121 0,13229537 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,09964121 0,13222351 ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,09964121 0,13215173 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,09964121 0,13208002 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,09964121 0,13200839 ! regulation of cell killing GO:0031341 46 21 0,000 0,1043554 0,13817899 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,1043554 0,13810414 ! hormone secretion GO:0046879 39 21 0,000 0,1043554 0,13802936 ! cAMP metabolic process GO:0046058 41 21 0,000 0,1043554 0,13795467 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,1043554 0,13788006 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,1043554 0,13780553 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,1043554 0,13773108 ! ovarian follicle development GO:0001541 39 21 0,000 0,1043554 0,13765671 ! smooth muscle contraction GO:0006939 48 21 0,000 0,1043554 0,13758243 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,1043554 0,13750822 ! cell structure disassembly during apoptosis GO:0006921 32 21 0,000 0,1043554 0,13743409 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,1043554 0,13736004 ! plasma membrane fusion GO:0045026 33 21 0,000 0,1043554 0,13728607 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,1043554 0,13721218 GO:0006692|prostanoid metabolic process, ! regulation of vasoconstriction GO:0019229 40 21 0,000 0,1043554 0,13713837 ! sensory perception of pain GO:0019233 33 21 0,000 0,1043554 0,13706464 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,1043554 0,13699099 ! diencephalon development GO:0021536 36 21 0,000 0,1043554 0,13691742 ! collagen fibril organization GO:0030199 62 21 0,000 0,1043554 0,13684393 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,1043554 0,13677051 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 0,1043554 0,13669718 ! collagen catabolic process GO:0030574 29 21 0,000 0,1043554 0,13662392 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,1043554 0,13655074 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,1043554 0,13647764 ! sperm-egg recognition GO:0035036 23 21 0,000 0,1043554 0,13640462 ! actin filament-based movement GO:0030048 47 21 0,000 0,1043554 0,13633168 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 0,000 0,1043554 0,13625881 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,10904503 0,1423061 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,10904503 0,14223012 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,10904503 0,14215422 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,10904503 0,14207841 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,10904503 0,14200267 ! hindlimb morphogenesis GO:0035137 47 22 0,000 0,10904503 0,14192702 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,10904503 0,14185144 ! cellular response to starvation GO:0009267 37 22 0,000 0,10904503 0,14177595 ! vacuolar transport GO:0007034 41 22 0,000 0,10904503 0,14170054 ! central nervous system neuron development GO:0021954 47 22 0,000 0,10904503 0,14162521 ! fucose metabolic process GO:0006004 44 22 0,000 0,10904503 0,14154995 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,10904503 0,14147478 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,10904503 0,14139969 ! apoptotic nuclear changes GO:0030262 34 22 0,000 0,10904503 0,14132468 ! ureteric bud development GO:0001657 50 22 0,000 0,10904503 0,14124974 ! cell aging GO:0007569 48 22 0,000 0,10904503 0,14117489 ! stem cell differentiation GO:0048863 57 22 0,000 0,10904503 0,14110011 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 0,10904503 0,14102542 ! cytolysis GO:0019835 27 22 0,000 0,10904503 0,1409508 ! renal system process GO:0003014 42 22 0,000 0,10904503 0,14087626 ! vasodilation GO:0042311 40 22 0,000 0,10904503 0,1408018 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,10904503 0,14072742 ! G1 phase GO:0051318 44 22 0,000 0,10904503 0,14065312 ! detection of chemical stimulus GO:0009593 42 22 0,000 0,10904503 0,1405789 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,10904503 0,14050475 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,10904503 0,14043069 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,10904503 0,1403567 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,10904503 0,14028279 ! sarcomere organization GO:0045214 32 22 0,000 0,10904503 0,14020895 ! positive regulation of B cell activation GO:0050871 42 22 0,000 0,10904503 0,1401352 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,10904503 0,14006152 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,10904503 0,13998792 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,10904503 0,1399144 ! gut development GO:0048565 44 22 0,000 0,10904503 0,13984095 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,10904503 0,13976758 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,10904503 0,13969429 ! protein stabilization GO:0050821 41 22 0,000 0,10904503 0,13962108 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,11371024 0,14551814 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,11371024 0,14544195 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,11371024 0,14536584 ! gluconeogenesis GO:0006094 38 23 0,000 0,11371024 0,14528981 ! glycerol metabolic process GO:0006071 40 23 0,000 0,11371024 0,14521386 ! viral genome replication GO:0019079 44 23 0,000 0,11371024 0,145138 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,11371024 0,14506221 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,11371024 0,14498649 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,11371024 0,14491086 ! regeneration GO:0031099 42 23 0,000 0,11371024 0,14483531 ! axis specification GO:0009798 43 23 0,000 0,11371024 0,14475984 ! visual behavior GO:0007632 46 23 0,000 0,11371024 0,14468444 ! regulation of cell-matrix adhesion GO:0001952 81 23 0,000 0,11371024 0,14460912 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 51 23 0,000 0,11371024 0,14453388 ! response to ethanol GO:0045471 47 23 0,000 0,11371024 0,14445872 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,11371024 0,14438364 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,11371024 0,14430864 ! peroxisome organization GO:0007031 43 23 0,000 0,11371024 0,14423371 ! lysosome organization GO:0007040 47 23 0,000 0,11371024 0,14415886 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 0,11371024 0,14408409 ! vesicle targeting GO:0006903 49 23 0,000 0,11371024 0,1440094 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 0,000 0,11371024 0,14393478 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,11371024 0,14386024 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,11371024 0,14378578 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,11371024 0,14371139 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,11371024 0,14363709 ! DNA modification GO:0006304 36 23 0,000 0,11371024 0,14356285 ! fatty acid transport GO:0015908 47 23 0,000 0,11371024 0,1434887 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,11371024 0,14341462 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,11371024 0,14334062 ! hormone transport GO:0009914 41 23 0,000 0,11371024 0,1432667 ! cell-cell recognition GO:0009988 28 23 0,000 0,11371024 0,14319285 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,11371024 0,14311907 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,11371024 0,14304538 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,11835116 0,14880694 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,11835116 0,14873039 GO:0016444|somatic cell DNA recombination, ! DNA catabolic process, endonucleolytic GO:0000737 38 24 0,000 0,11835116 0,14865392 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,11835116 0,14857753 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,11835116 0,14850122 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,11835116 0,14842499 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,11835116 0,14834883 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 0,11835116 0,14827276 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,11835116 0,14819676 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,11835116 0,14812084 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,11835116 0,148045 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,11835116 0,14796923 GO:0042278|purine nucleoside metabolic process, ! positive regulation of cytoskeleton organization GO:0051495 52 24 0,000 0,11835116 0,14789354 ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,11835116 0,14781793 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,11835116 0,1477424 GO:0051693|actin filament capping, ! regulation of viral reproduction GO:0050792 41 24 0,000 0,11835116 0,14766694 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,11835116 0,14759156 GO:0002708|positive regulation of lymphocyte mediated immunity, ! leukotriene metabolic process GO:0006691 47 24 0,000 0,11835116 0,14751626 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,11835116 0,14744104 ! membrane depolarization GO:0051899 45 24 0,000 0,11835116 0,14736589 ! pallium development GO:0021543 56 24 0,000 0,11835116 0,14729082 ! oogenesis GO:0048477 44 24 0,000 0,11835116 0,14721582 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,11835116 0,1471409 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,11835116 0,14706606 ! platelet activation GO:0030168 41 24 0,000 0,11835116 0,14699129 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,11835116 0,1469166 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,11835116 0,14684199 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,11835116 0,14676745 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,11835116 0,14669299 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,11835116 0,1466186 ! negative regulation of catabolic process GO:0009895 52 24 0,000 0,11835116 0,14654429 ! regulation of amine transport GO:0051952 41 24 0,000 0,11835116 0,14647005 ! positive regulation of fibroblast proliferation GO:0048146 48 25 0,000 0,1229679 0,15210662 ! myeloid leukocyte differentiation GO:0002573 46 25 0,000 0,1229679 0,15202964 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 0,000 0,1229679 0,15195275 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,1229679 0,15187592 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,1229679 0,15179918 ! phototransduction GO:0007602 37 25 0,000 0,1229679 0,15172251 ! keratinization GO:0031424 37 25 0,000 0,1229679 0,15164592 ! vacuole organization GO:0007033 49 25 0,000 0,1229679 0,15156941 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,1229679 0,15149298 ! negative regulation of DNA replication GO:0008156 45 25 0,000 0,1229679 0,15141662 ! receptor metabolic process GO:0043112 53 25 0,000 0,1229679 0,15134034 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,1229679 0,15126414 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,1229679 0,15118801 ! immunoglobulin production GO:0002377 62 25 0,000 0,1229679 0,15111196 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,1229679 0,15103599 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,1229679 0,15096009 ! liver development GO:0001889 55 25 0,000 0,1229679 0,15088427 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,12756059 0,15644103 ! initiation of viral infection GO:0019059 60 26 0,000 0,12756059 0,15636254 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,12756059 0,15628412 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,12756059 0,15620578 ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,12756059 0,15612752 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,12756059 0,15604934 GO:0006479|protein amino acid methylation, ! microtubule organizing center organization GO:0031023 42 26 0,000 0,12756059 0,15597124 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,12756059 0,15589321 ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,12756059 0,15581527 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,12756059 0,1557374 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,12756059 0,15565961 ! regulation of cellular ketone metabolic process GO:0010565 51 26 0,000 0,12756059 0,15558189 ! osteoblast differentiation GO:0001649 63 26 0,000 0,12756059 0,15550426 ! neural crest cell development GO:0014032 59 26 0,000 0,12756059 0,1554267 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,12756059 0,15534922 ! negative regulation of cell development GO:0010721 83 26 0,000 0,12756059 0,15527182 GO:0050768|negative regulation of neurogenesis, ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,12756059 0,15519449 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,12756059 0,15511724 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,12756059 0,15504007 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,12756059 0,15496297 ! regulation of blood coagulation GO:0030193 46 26 0,000 0,12756059 0,15488595 ! regulation of osteoblast differentiation GO:0045667 68 26 0,000 0,12756059 0,15480901 ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,12756059 0,15473214 ! blastocyst development GO:0001824 50 26 0,000 0,12756059 0,15465535 ! telomere organization GO:0032200 46 26 0,000 0,12756059 0,15457864 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,12756059 0,154502 ! neural tube closure GO:0001843 58 26 0,000 0,12756059 0,15442544 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 44 26 0,000 0,12756059 0,15434895 ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,12756059 0,15427254 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,12756059 0,15419621 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,13212937 0,15963998 ! embryonic pattern specification GO:0009880 49 27 0,000 0,13212937 0,15956107 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,13212937 0,15948224 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,13212937 0,15940348 ! positive regulation of cell projection organization GO:0031346 66 27 0,000 0,13212937 0,1593248 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,13212937 0,1592462 ! iron ion transport GO:0006826 65 27 0,000 0,13212937 0,15916768 ! superoxide metabolic process GO:0006801 41 27 0,000 0,13212937 0,15908923 ! tube lumen formation GO:0035148 59 27 0,000 0,13212937 0,15901086 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,13212937 0,15893257 ! mitochondrial membrane organization GO:0007006 60 27 0,000 0,13212937 0,15885435 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,13212937 0,15877622 ! response to starvation GO:0042594 47 27 0,000 0,13212937 0,15869816 ! response to toxin GO:0009636 49 27 0,000 0,13212937 0,15862017 ! cellular response to nutrient levels GO:0031669 45 27 0,000 0,13212937 0,15854226 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,13212937 0,15846443 ! leukocyte proliferation GO:0070661 59 27 0,000 0,13212937 0,15838668 GO:0032943|mononuclear cell proliferation, ! regulation of fibroblast proliferation GO:0048145 56 28 0,000 0,13667435 0,1637545 ! neuron fate commitment GO:0048663 52 28 0,000 0,13667435 0,16367423 ! vesicle docking GO:0048278 55 28 0,000 0,13667435 0,16359404 ! circadian rhythm GO:0007623 56 28 0,000 0,13667435 0,16351392 ! fat cell differentiation GO:0045444 57 28 0,000 0,13667435 0,16343389 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,13667435 0,16335393 ! sperm motility GO:0030317 37 28 0,000 0,13667435 0,16327405 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,13667435 0,16319425 ! base-excision repair GO:0006284 41 28 0,000 0,13667435 0,16311452 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,13667435 0,16303488 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,13667435 0,16295531 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,13667435 0,16287582 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,13667435 0,16279641 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,13667435 0,16271707 ! glutathione metabolic process GO:0006749 42 28 0,000 0,13667435 0,16263781 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,13667435 0,16255863 ! lipid oxidation GO:0034440 48 28 0,000 0,13667435 0,16247953 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,13667435 0,1624005 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,13667435 0,16232155 ! translational initiation GO:0006413 66 29 0,000 0,14119565 0,1676098 ! cellular iron ion homeostasis GO:0006879 57 29 0,000 0,14119565 0,1675284 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,14119565 0,16744707 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,14119565 0,16736583 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! autophagy GO:0006914 47 29 0,000 0,14119565 0,16728466 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,14119565 0,16720357 ! primary neural tube formation GO:0014020 61 29 0,000 0,14119565 0,16712256 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,14119565 0,16704163 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,14119565 0,16696078 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,14119565 0,16688 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 0,000 0,14119565 0,16679931 ! synaptogenesis GO:0007416 46 29 0,000 0,14119565 0,16671869 ! negative regulation of neuron differentiation GO:0045665 46 29 0,000 0,14119565 0,16663815 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,14119565 0,16655769 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,14119565 0,1664773 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,14119565 0,16639699 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,1456934 0,17161474 ! phenol metabolic process GO:0018958 56 30 0,000 0,1456934 0,17153204 ! negative regulation of protein complex assembly GO:0031333 68 30 0,000 0,1456934 0,17144941 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,1456934 0,17136686 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,1456934 0,1712844 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,1456934 0,17120201 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,1456934 0,1711197 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,1456934 0,17103747 ! acute-phase response GO:0006953 50 30 0,000 0,1456934 0,17095532 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,1456934 0,17087325 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,1456934 0,17079125 ! myofibril assembly GO:0030239 50 30 0,000 0,1456934 0,17070934 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 72 30 0,000 0,1456934 0,1706275 ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,1456934 0,17054575 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,1456934 0,17046407 ! cell fate determination GO:0001709 64 30 0,000 0,1456934 0,17038247 ! phospholipid transport GO:0015914 65 30 0,000 0,1456934 0,17030094 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,1456934 0,1702195 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,1456934 0,17013813 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,1456934 0,17005684 ! negative regulation of transcription regulator activity GO:0090048 57 30 0,000 0,1456934 0,16997563 GO:0043433|negative regulation of transcription factor activity, ! regulation of B cell activation GO:0050864 55 30 0,000 0,1456934 0,1698945 ! regulation of coagulation GO:0050818 52 30 0,000 0,1456934 0,16981344 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,15016772 0,17494504 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,15016772 0,17486165 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,15016772 0,17477834 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,15016772 0,17469511 ! regulation of innate immune response GO:0045088 57 31 0,000 0,15016772 0,17461197 ! ovulation cycle process GO:0022602 55 31 0,000 0,15016772 0,1745289 ! peptide transport GO:0015833 60 31 0,000 0,15016772 0,17444591 ! iron ion homeostasis GO:0055072 60 31 0,000 0,15016772 0,17436299 ! detection of light stimulus GO:0009583 44 31 0,000 0,15016772 0,17428016 ! cellular response to extracellular stimulus GO:0031668 52 31 0,000 0,15016772 0,17419741 ! cofactor catabolic process GO:0051187 54 31 0,000 0,15016772 0,17411473 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,15016772 0,17403213 ! eye morphogenesis GO:0048592 65 31 0,000 0,15016772 0,17394962 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,15016772 0,17386717 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,15461873 0,17893584 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,15461873 0,17885112 ! collagen metabolic process GO:0032963 49 32 0,000 0,15461873 0,17876648 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,15461873 0,17868191 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,15461873 0,17859743 ! response to mechanical stimulus GO:0009612 60 32 0,000 0,15461873 0,17851303 ! muscle cell development GO:0055001 52 32 0,000 0,15461873 0,1784287 ! mesoderm formation GO:0001707 73 32 0,000 0,15461873 0,17834446 ! hexose biosynthetic process GO:0019319 53 32 0,000 0,15461873 0,17826029 ! ovulation cycle GO:0042698 57 32 0,000 0,15461873 0,17817621 ! BMP signaling pathway GO:0030509 71 32 0,000 0,15461873 0,1780922 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,15461873 0,17800828 ! regulation of pH GO:0006885 56 33 0,000 0,15904656 0,18301966 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,15904656 0,18293349 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,15904656 0,18284741 GO:0055092|sterol homeostasis, ! pigment biosynthetic process GO:0046148 73 33 0,000 0,15904656 0,1827614 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,15904656 0,18267548 ! triglyceride metabolic process GO:0006641 46 33 0,000 0,15904656 0,18258963 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,15904656 0,18250387 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,15904656 0,18241819 ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,15904656 0,18233258 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,15904656 0,18224706 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,15904656 0,18216162 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,16345131 0,18711882 ! glial cell differentiation GO:0010001 67 34 0,000 0,16345131 0,18703118 ! post-embryonic development GO:0009791 76 34 0,000 0,16345131 0,18694361 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,16345131 0,18685614 ! cholesterol transport GO:0030301 62 34 0,000 0,16345131 0,18676874 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,16345131 0,18668142 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,16345131 0,18659419 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,16345131 0,18650703 ! formation of primary germ layer GO:0001704 76 34 0,000 0,16345131 0,18641996 ! cell fate specification GO:0001708 56 34 0,000 0,16345131 0,18633297 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,16345131 0,18624606 ! adult locomotory behavior GO:0008344 62 34 0,000 0,16345131 0,18615924 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,16783312 0,19106073 ! negative regulation of secretion GO:0051048 68 35 0,000 0,16783312 0,19097174 ! negative regulation of DNA metabolic process GO:0051053 65 35 0,000 0,16783312 0,19088283 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,16783312 0,19079401 ! membrane docking GO:0022406 69 35 0,000 0,16783312 0,19070527 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,16783312 0,19061661 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,16783312 0,19052803 ! regulation of striated muscle tissue development GO:0016202 81 35 0,000 0,16783312 0,19043954 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,16783312 0,19035112 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,16783312 0,19026279 ! ceramide metabolic process GO:0006672 72 35 0,000 0,16783312 0,19017455 ! telencephalon development GO:0021537 81 35 0,000 0,16783312 0,19008638 ! sterol transport GO:0015918 63 35 0,000 0,16783312 0,1899983 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,16783312 0,18991029 ! vesicle localization GO:0051648 70 35 0,000 0,16783312 0,18982237 ! regulation of muscle development GO:0048634 82 36 0,000 0,1721921 0,19466234 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,1721921 0,1945723 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,1721921 0,19448234 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,1721921 0,19439247 ! negative regulation of DNA binding GO:0043392 67 36 0,000 0,1721921 0,19430268 ! positive regulation of cell development GO:0010720 85 36 0,000 0,1721921 0,19421298 ! protein targeting to membrane GO:0006612 75 36 0,000 0,1721921 0,19412336 ! negative regulation of hydrolase activity GO:0051346 66 36 0,000 0,1721921 0,19403381 ! cytokine production GO:0001816 68 36 0,000 0,1721921 0,19394436 ! embryonic organ development GO:0048568 67 36 0,000 0,1721921 0,19385498 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,1721921 0,19376569 ! monosaccharide biosynthetic process GO:0046364 57 36 0,000 0,1721921 0,19367648 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 0,000 0,17652837 0,19846241 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! negative regulation of cell adhesion GO:0007162 94 37 0,000 0,17652837 0,19837112 ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,17652837 0,19827992 ! odontogenesis GO:0042476 74 37 0,000 0,17652837 0,19818879 ! actomyosin structure organization GO:0031032 68 37 0,000 0,17652837 0,19809776 ! female gonad development GO:0008585 71 37 0,000 0,17652837 0,1980068 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,17652837 0,19791593 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,18084205 0,20265923 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,18084205 0,20256631 ! organic anion transport GO:0015711 82 38 0,000 0,18084205 0,20247348 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,18084205 0,20238073 ! neutral lipid metabolic process GO:0006638 54 38 0,000 0,18084205 0,20228806 GO:0006639|acylglycerol metabolic process, ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,18084205 0,20219548 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,18084205 0,20210299 ! regulation of protein stability GO:0031647 77 38 0,000 0,18084205 0,20201058 ! spermatid development GO:0007286 69 38 0,000 0,18084205 0,20191825 ! pigment metabolic process GO:0042440 87 38 0,000 0,18084205 0,20182601 ! neural tube formation GO:0001841 79 38 0,000 0,18084205 0,20173385 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,18513325 0,20642653 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,18513325 0,20633236 ! negative regulation of binding GO:0051100 71 39 0,000 0,18513325 0,20623827 ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,18513325 0,20614427 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,18513325 0,20605036 ! positive regulation of leukocyte proliferation GO:0070665 70 39 0,000 0,18513325 0,20595653 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,18513325 0,20586278 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,18940209 0,21051379 GO:0006956|complement activation, ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,18940209 0,21041806 ! learning GO:0007612 82 40 0,000 0,18940209 0,21032242 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,18940209 0,21022686 GO:0046660|female sex differentiation, ! lipid homeostasis GO:0055088 75 40 0,000 0,18940209 0,21013139 ! mismatch repair GO:0006298 58 40 0,000 0,18940209 0,210036 ! glycerol ether metabolic process GO:0006662 57 40 0,000 0,18940209 0,2099407 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,18940209 0,20984549 ! RNA export from nucleus GO:0006405 61 41 0,000 0,19364869 0,2144532 ! mRNA catabolic process GO:0006402 79 41 0,000 0,19364869 0,21435603 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,19364869 0,21425895 ! regulation of hormone secretion GO:0046883 69 41 0,000 0,19364869 0,21416195 ! establishment or maintenance of cell polarity GO:0007163 96 41 0,000 0,19364869 0,21406505 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,19364869 0,21396823 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,19364869 0,2138715 ! gliogenesis GO:0042063 91 41 0,000 0,19364869 0,21377485 ! feeding behavior GO:0007631 69 41 0,000 0,19364869 0,2136783 ! multicellular organismal metabolic process GO:0044236 64 41 0,000 0,19364869 0,21358183 ! monovalent inorganic cation homeostasis GO:0055067 72 41 0,000 0,19364869 0,21348545 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,19364869 0,21338915 GO:0015986|ATP synthesis coupled proton transport, ! spermatid differentiation GO:0048515 73 41 0,000 0,19364869 0,21329295 ! embryonic epithelial tube formation GO:0001838 85 41 0,000 0,19364869 0,21319682 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,19787316 0,21774961 ! ear morphogenesis GO:0042471 64 42 0,000 0,19787316 0,21765157 ! organic ether metabolic process GO:0018904 59 42 0,000 0,19787316 0,21755361 ! alcohol biosynthetic process GO:0046165 65 42 0,000 0,19787316 0,21745575 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,19787316 0,21735797 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,19787316 0,21726028 ! regulation of protein secretion GO:0050708 77 42 0,000 0,19787316 0,21716268 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,20207562 0,22167523 ! regulation of tube size GO:0035150 76 43 0,000 0,20207562 0,22157573 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,20207562 0,22147633 ! striated muscle cell differentiation GO:0051146 91 43 0,000 0,20207562 0,22137701 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,20207562 0,22127778 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,20207562 0,22117864 ! ion transmembrane transport GO:0034220 79 43 0,000 0,20207562 0,22107959 ! neuron migration GO:0001764 85 43 0,000 0,20207562 0,22098063 ! response to reactive oxygen species GO:0000302 75 44 0,000 0,20625617 0,22545138 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,20625617 0,22535055 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 0,000 0,20625617 0,22524981 ! striated muscle contraction GO:0006941 85 44 0,000 0,20625617 0,22514916 ! phagocytosis GO:0006909 105 44 0,000 0,20625617 0,22504861 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,20625617 0,22494814 ! double-strand break repair GO:0006302 85 44 0,000 0,20625617 0,22484776 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,21041494 0,22927908 ! branching morphogenesis of a tube GO:0048754 102 45 0,000 0,21041494 0,22917686 ! keratinocyte differentiation GO:0030216 81 45 0,000 0,21041494 0,22907474 ! biopolymer methylation GO:0043414 91 45 0,000 0,21041494 0,2289727 ! B cell differentiation GO:0030183 124 45 0,000 0,21041494 0,22887075 ! female gamete generation GO:0007292 71 45 0,000 0,21041494 0,2287689 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,21041494 0,22866713 ! polyol metabolic process GO:0019751 77 45 0,000 0,21041494 0,22856545 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,21455204 0,23295584 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,21455204 0,23285235 ! glycolysis GO:0006096 71 46 0,000 0,21455204 0,23274895 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,21455204 0,23264564 ! pigmentation GO:0043473 103 46 0,000 0,21455204 0,23254243 ! cell growth GO:0016049 90 46 0,000 0,21455204 0,23243931 ! neural tube development GO:0021915 91 47 0,000 0,21866758 0,23679295 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,21866758 0,23668803 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,22276167 0,24101273 ! mitochondrial transport GO:0006839 94 48 0,000 0,22276167 0,24090604 ! regulation of JAK-STAT cascade GO:0046425 76 48 0,000 0,22276167 0,24079945 ! cellular component disassembly GO:0022411 89 48 0,000 0,22276167 0,24069294 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 0,000 0,22276167 0,24058654 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,22276167 0,24048022 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,22276167 0,24037401 ! methylation GO:0032259 97 48 0,000 0,22276167 0,24026788 ! response to calcium ion GO:0051592 94 49 0,000 0,22683442 0,24455273 ! detection of stimulus involved in sensory perception GO:0050906 75 49 0,000 0,22683442 0,24444485 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,22683442 0,24433707 ! JNK cascade GO:0007254 106 49 0,000 0,22683442 0,24422939 ! regulation of ion transport GO:0043269 86 50 0,000 0,23088594 0,24848209 ! endocrine system development GO:0035270 109 50 0,000 0,23088594 0,24837268 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,23088594 0,24826336 ! activation of caspase activity GO:0006919 95 50 0,000 0,23088594 0,24815413 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,23088594 0,24804501 GO:0019724|B cell mediated immunity, ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,23088594 0,24793598 ! epidermal cell differentiation GO:0009913 87 50 0,000 0,23088594 0,24782704 ! regulation of cell projection organization GO:0031344 135 51 0,000 0,23491634 0,25204244 ! viral infectious cycle GO:0019058 104 51 0,000 0,23491634 0,25193179 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,23491634 0,25182125 ! detection of abiotic stimulus GO:0009582 80 51 0,000 0,23491634 0,2517108 ! Notch signaling pathway GO:0007219 111 52 0,000 0,23892574 0,2558946 ! morphogenesis of embryonic epithelium GO:0016331 106 52 0,000 0,23892574 0,25578247 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,23892574 0,25567043 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,23892574 0,25555849 ! excretion GO:0007588 87 52 0,000 0,23892574 0,25544665 ! DNA-dependent DNA replication GO:0006261 82 52 0,000 0,23892574 0,2553349 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,23892574 0,25522326 ! morphogenesis of a branching structure GO:0001763 116 52 0,000 0,23892574 0,25511171 ! inner ear development GO:0048839 89 53 0,000 0,24291424 0,25925709 ! chromatin remodeling GO:0006338 122 53 0,000 0,24291424 0,25914388 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,24291424 0,25903077 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,24291424 0,25891775 ! vesicle organization GO:0016050 127 53 0,000 0,24291424 0,25880484 ! regulation of neuron apoptosis GO:0043523 117 53 0,000 0,24291424 0,25869202 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,24688195 0,26280288 ! neuromuscular process GO:0050905 107 54 0,000 0,24688195 0,26268842 ! membrane fusion GO:0006944 122 54 0,000 0,24688195 0,26257405 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,24688195 0,26245979 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,24688195 0,26234563 ! epithelial tube morphogenesis GO:0060562 114 54 0,000 0,24688195 0,26223157 ! RNA catabolic process GO:0006401 103 55 0,000 0,25082898 0,26630821 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,25082898 0,26619252 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,25082898 0,26607694 ! cell recognition GO:0008037 98 55 0,000 0,25082898 0,26596145 ! cell maturation GO:0048469 107 55 0,000 0,25082898 0,26584607 ! regulation of protein polymerization GO:0032271 117 55 0,000 0,25082898 0,26573078 ! glucose catabolic process GO:0006007 88 56 0,000 0,25475543 0,26977352 ! RNA elongation GO:0006354 90 56 0,000 0,25475543 0,26965663 ! chloride transport GO:0006821 102 57 0,000 0,25866141 0,27367251 ! positive regulation of caspase activity GO:0043280 108 57 0,000 0,25866141 0,27355403 GO:0010952|positive regulation of peptidase activity, ! nucleotide-excision repair GO:0006289 91 57 0,000 0,25866141 0,27343566 ! regulation of actin filament length GO:0030832 118 58 0,000 0,26254703 0,27742318 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,26254703 0,27730324 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,26254703 0,2771834 ! aging GO:0007568 112 58 0,000 0,26254703 0,27706367 ! gastrulation GO:0007369 122 58 0,000 0,26254703 0,27694404 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,26254703 0,27682451 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,2702576 0,28483146 ! regulation of endocytosis GO:0030100 104 60 0,000 0,2702576 0,28470863 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,2702576 0,28458591 ! adult behavior GO:0030534 104 60 0,000 0,2702576 0,2844633 ! positive regulation of secretion GO:0051047 110 61 0,000 0,27408276 0,28836529 ! regulation of cellular component size GO:0032535 125 61 0,000 0,27408276 0,28824115 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,27408276 0,28811712 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,27408276 0,2879932 ! cytokine-mediated signaling pathway GO:0019221 112 61 0,000 0,27408276 0,28786939 ! proton transport GO:0015992 117 61 0,000 0,27408276 0,28774568 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,27788798 0,29161527 ! tRNA processing GO:0008033 102 62 0,000 0,27788798 0,29149006 ! regulation of protein complex assembly GO:0043254 132 63 0,000 0,28167336 0,29533392 ! mesoderm development GO:0007498 128 63 0,000 0,28167336 0,29520722 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,28167336 0,29508063 ! hydrogen transport GO:0006818 121 64 0,000 0,28543901 0,29889734 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,28543901 0,29876928 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,28918501 0,30256059 ! lymphocyte mediated immunity GO:0002449 122 65 0,000 0,28918501 0,30243107 ! multicellular organism reproduction GO:0032504 123 65 0,000 0,28918501 0,30230166 GO:0048609|reproductive process in a multicellular organism, ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,28918501 0,30217236 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,28918501 0,30204317 ! ear development GO:0043583 114 66 0,000 0,29291149 0,3058046 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,29291149 0,30567397 ! regulation of lipid metabolic process GO:0019216 132 66 0,000 0,29291149 0,30554345 ! embryonic limb morphogenesis GO:0030326 139 67 0,000 0,29661853 0,3092783 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,29661853 0,30914636 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,29661853 0,30901453 ! secondary metabolic process GO:0019748 125 67 0,000 0,29661853 0,30888281 ! regulation of cellular response to stress GO:0080135 142 68 0,000 0,30030624 0,31258975 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,30030624 0,31245662 ! hexose catabolic process GO:0019320 113 68 0,000 0,30030624 0,31232361 ! extracellular matrix organization GO:0030198 146 68 0,000 0,30030624 0,3121907 ! negative regulation of ligase activity GO:0051352 116 68 0,000 0,30030624 0,31205791 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! detection of external stimulus GO:0009581 102 68 0,000 0,30030624 0,31192523 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 0,000 0,30030624 0,31179267 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,30397472 0,3154674 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 0,000 0,30397472 0,31533344 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,30397472 0,3151996 ! single fertilization GO:0007338 83 69 0,000 0,30397472 0,31506587 ! cell redox homeostasis GO:0045454 114 70 0,000 0,30762407 0,31871315 ! activation of immune response GO:0002253 120 70 0,000 0,30762407 0,31857805 ! protein maturation by peptide bond cleavage GO:0051605 118 70 0,000 0,30762407 0,31844306 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,31125439 0,32206458 ! cAMP-mediated signaling GO:0019933 124 71 0,000 0,31125439 0,32192823 ! appendage morphogenesis GO:0035107 150 72 0,000 0,31486578 0,32552564 GO:0035108|limb morphogenesis, ! actin filament organization GO:0007015 167 72 0,000 0,31486578 0,32538794 ! B cell activation GO:0042113 179 72 0,000 0,31486578 0,32525036 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 0,000 0,31486578 0,32511289 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 0,000 0,31486578 0,32497554 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,31486578 0,3248383 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,31486578 0,32470118 ! regulation of MAPKKK cascade GO:0043408 157 72 0,000 0,31486578 0,32456417 ! appendage development GO:0048736 151 73 0,000 0,31845833 0,32812893 GO:0060173|limb development, ! humoral immune response GO:0006959 115 73 0,000 0,31845833 0,3279906 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,31845833 0,32785238 ! regulation of immune effector process GO:0002697 156 73 0,000 0,31845833 0,32771428 ! acute inflammatory response GO:0002526 118 74 0,000 0,32203214 0,33125243 ! amino acid transport GO:0006865 148 74 0,000 0,32203214 0,33111301 ! transition metal ion transport GO:0000041 143 75 0,000 0,32558732 0,3346276 ! leukocyte mediated immunity GO:0002443 136 75 0,000 0,32558732 0,33448689 ! rhythmic process GO:0048511 142 75 0,000 0,32558732 0,33434629 ! cell-matrix adhesion GO:0007160 181 76 0,000 0,32912395 0,33783605 ! regulation of actin cytoskeleton organization GO:0032956 167 76 0,000 0,32912395 0,33769416 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,32912395 0,33755239 ! regulation of blood pressure GO:0008217 134 76 0,000 0,32912395 0,33741074 ! amine catabolic process GO:0009310 136 77 0,000 0,33264213 0,34087447 ! neurotransmitter transport GO:0006836 142 77 0,000 0,33264213 0,34073154 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,33264213 0,34058874 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,33264213 0,34044605 ! positive regulation of ligase activity GO:0051351 130 77 0,000 0,33264213 0,34030349 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,33264213 0,34016104 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,33614196 0,34359616 ! antigen processing and presentation GO:0019882 117 78 0,000 0,33614196 0,34345245 ! fertilization GO:0009566 99 78 0,000 0,33614196 0,34330887 ! blood coagulation GO:0007596 151 79 0,000 0,33962354 0,34671973 GO:0050817|coagulation, ! regulation of actin filament-based process GO:0032970 170 79 0,000 0,33962354 0,3465749 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 0,000 0,33962354 0,34643019 ! steroid biosynthetic process GO:0006694 146 79 0,000 0,33962354 0,3462856 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 0,000 0,34308696 0,34967102 ! activation of protein kinase activity GO:0032147 170 80 0,000 0,34308696 0,3495252 ! muscle cell differentiation GO:0042692 178 81 0,000 0,3465323 0,35288804 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 0,000 0,3465323 0,35274101 ! cell-substrate adhesion GO:0031589 189 82 0,000 0,34995968 0,35608142 ! regulation of adenylate cyclase activity GO:0045761 165 83 0,000 0,35336917 0,35940087 ! exocytosis GO:0006887 153 83 0,000 0,35336917 0,35925131 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,35336917 0,35910187 ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,35336917 0,35895255 ! response to metal ion GO:0010038 158 84 0,000 0,35676088 0,36224723 ! regulation of ligase activity GO:0051340 147 84 0,000 0,35676088 0,36209673 ! hemostasis GO:0007599 165 85 0,000 0,36013489 0,36536941 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,36013489 0,36521774 ! regulation of cyclase activity GO:0031279 168 85 0,000 0,36013489 0,3650662 ! regulation of cAMP biosynthetic process GO:0030817 173 86 0,000 0,3634913 0,36831574 ! regulation of lyase activity GO:0051339 169 86 0,000 0,3634913 0,36816304 ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,3668302 0,37139087 ! alcohol catabolic process GO:0046164 142 87 0,000 0,3668302 0,37123702 ! nucleosome assembly GO:0006334 126 87 0,000 0,3668302 0,3710833 ! amine biosynthetic process GO:0009309 146 88 0,000 0,37015168 0,3742883 ! sensory perception of smell GO:0007608 117 88 0,000 0,37015168 0,37413345 ! chromatin assembly GO:0031497 128 88 0,000 0,37015168 0,37397872 ! one-carbon metabolic process GO:0006730 167 88 0,000 0,37015168 0,37382412 ! regulation of cAMP metabolic process GO:0030814 182 89 0,000 0,37345582 0,37700519 ! tube morphogenesis GO:0035239 194 89 0,000 0,37345582 0,37684947 ! cellular defense response GO:0006968 123 89 0,000 0,37345582 0,37669388 ! response to inorganic substance GO:0010035 173 90 0,000 0,37674273 0,37985245 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 0,000 0,38001248 0,38299113 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! defense response to bacterium GO:0042742 112 91 0,000 0,38001248 0,38283319 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,38326517 0,38595087 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 0,000 0,38650089 0,3890489 GO:0010498|proteasomal protein catabolic process, ! amine transport GO:0015837 181 93 0,000 0,38650089 0,38888866 ! vitamin metabolic process GO:0006766 153 93 0,000 0,38650089 0,38872856 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,38971972 0,39180464 ! female pregnancy GO:0007565 166 94 0,000 0,38971972 0,39164347 ! sterol metabolic process GO:0016125 166 94 0,000 0,38971972 0,39148243 ! nucleosome organization GO:0034728 143 95 0,000 0,39292176 0,39453672 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,39292176 0,39437463 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 0,000 0,39292176 0,39421267 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,39292176 0,39405084 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,39292176 0,39388915 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,39927578 0,40009464 ! transcription initiation GO:0006352 171 97 0,000 0,39927578 0,3999306 ! forebrain development GO:0030900 210 98 0,000 0,40242794 0,40292273 ! regulation of nucleotide metabolic process GO:0006140 197 98 0,000 0,40242794 0,40275767 ! positive regulation of immune response GO:0050778 175 100 0,000 0,408683 0,40885035 ! hormone metabolic process GO:0042445 171 100 0,000 0,408683 0,408683