pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6830-VanDeVijver-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/vantveer-oligo_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! positive regulation of cell motion GO:0051272 39 39 6,000 1,031E-08 1,9E-05 ! regulation of cell motion GO:0051270 79 79 7,000 9,009E-08 8,302E-05 ! positive regulation of cell migration GO:0030335 36 36 5,000 2,016E-07 1,238E-04 ! glucose homeostasis GO:0042593 24 24 4,000 7E-07 3,225E-04 GO:0033500|carbohydrate homeostasis, ! regulation of cell migration GO:0030334 71 71 6,000 7,443E-07 2,744E-04 ! regulation of locomotion GO:0040012 79 79 6,000 1,551E-06 4,764E-04 ! heart development GO:0007507 90 87 6,000 2,989E-06 7,868E-04 ! positive regulation of glucose metabolic process GO:0010907 5 5 2,000 3,798E-06 8,751E-04 ! positive regulation of catabolic process GO:0009896 16 16 3,000 4,566E-06 9,35E-04 ! tissue remodeling GO:0048771 17 17 3,000 5,938E-06 1,094E-03 ! regulation of oxidoreductase activity GO:0051341 17 17 3,000 5,938E-06 9,949E-04 ! lung development GO:0030324 38 37 4,000 6,676E-06 1,025E-03 ! ER overload response GO:0006983 6 6 2,000 7,557E-06 1,071E-03 ! regulation of RNA splicing GO:0043484 6 6 2,000 7,557E-06 9,948E-04 ! regulation of cellular carbohydrate catabolic process GO:0043471 6 6 2,000 7,557E-06 9,285E-04 GO:0043470|regulation of carbohydrate catabolic process, GO:0006110|regulation of glycolysis, ! epidermal growth factor receptor signaling pathway GO:0007173 18 18 3,000 7,593E-06 8,746E-04 ! regulation of homeostatic process GO:0032844 38 38 4,000 7,644E-06 8,287E-04 ! respiratory tube development GO:0030323 40 39 4,000 8,72E-06 8,928E-04 ! respiratory system development GO:0060541 40 39 4,000 8,72E-06 8,458E-04 ! positive regulation of cellular catabolic process GO:0031331 7 7 2,000 1,316E-05 1,212E-03 ! regulation of mRNA processing GO:0050684 7 7 2,000 1,316E-05 1,155E-03 ! cardiac muscle tissue development GO:0048738 7 7 2,000 1,316E-05 1,102E-03 ! positive regulation of carbohydrate metabolic process GO:0045913 7 7 2,000 1,316E-05 1,054E-03 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! positive regulation of endothelial cell migration GO:0010595 8 8 2,000 2,094E-05 1,608E-03 ! regulation of immunoglobulin production GO:0002637 8 8 2,000 2,094E-05 1,544E-03 ! regulation of generation of precursor metabolites and energy GO:0043467 8 8 2,000 2,094E-05 1,484E-03 ! regulation of catabolic process GO:0009894 48 47 4,000 2,222E-05 1,516E-03 ! T cell differentiation GO:0030217 24 24 3,000 2,551E-05 1,679E-03 ! positive regulation of MAP kinase activity GO:0043406 50 49 4,000 2,731E-05 1,736E-03 ! blood vessel morphogenesis GO:0048514 84 83 5,000 2,998E-05 1,842E-03 ! regulation of gene-specific transcription GO:0032583 25 25 3,000 3,021E-05 1,796E-03 ! regulation of intracellular protein transport GO:0033157 25 25 3,000 3,021E-05 1,74E-03 ! heart morphogenesis GO:0003007 25 25 3,000 3,021E-05 1,687E-03 ! regulation of nitric-oxide synthase activity GO:0050999 9 9 2,000 3,124E-05 1,694E-03 ! positive regulation of endothelial cell proliferation GO:0001938 9 9 2,000 3,124E-05 1,645E-03 ! platelet-derived growth factor receptor signaling pathway GO:0048008 9 9 2,000 3,124E-05 1,6E-03 ! positive regulation of oxidoreductase activity GO:0051353 9 9 2,000 3,124E-05 1,556E-03 ! positive regulation of protein kinase activity GO:0045860 89 86 5,000 3,672E-05 1,781E-03 ! response to hypoxia GO:0001666 53 53 4,000 4,019E-05 1,899E-03 ! regulation of protein transport GO:0051223 53 53 4,000 4,019E-05 1,852E-03 GO:0070201|regulation of establishment of protein localization, ! regulation of nucleocytoplasmic transport GO:0046822 27 27 3,000 4,145E-05 1,863E-03 ! positive regulation of transferase activity GO:0051347 91 88 5,000 4,186E-05 1,837E-03 GO:0033674|positive regulation of kinase activity, ! response to oxygen levels GO:0070482 55 54 4,000 4,405E-05 1,888E-03 ! regulation of glucose metabolic process GO:0010906 10 10 2,000 4,44E-05 1,86E-03 ! protein amino acid autophosphorylation GO:0046777 28 28 3,000 4,81E-05 1,97E-03 ! positive regulation of protein transport GO:0051222 29 29 3,000 5,549E-05 2,223E-03 ! regulation of protein localization GO:0032880 58 57 4,000 5,735E-05 2,249E-03 ! positive regulation of nucleocytoplasmic transport GO:0046824 11 11 2,000 6,073E-05 2,332E-03 GO:0032388|positive regulation of intracellular transport, ! cellular response to starvation GO:0009267 11 11 2,000 6,073E-05 2,284E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 11 11 2,000 6,073E-05 2,239E-03 ! regulation of monooxygenase activity GO:0032768 11 11 2,000 6,073E-05 2,195E-03 ! regulation of cellular carbohydrate metabolic process GO:0010675 11 11 2,000 6,073E-05 2,153E-03 GO:0006109|regulation of carbohydrate metabolic process, ! blood vessel development GO:0001568 95 94 5,000 6,08E-05 2,114E-03 ! vasculature development GO:0001944 97 96 5,000 6,845E-05 2,336E-03 ! regulation of intracellular transport GO:0032386 31 31 3,000 7,272E-05 2,437E-03 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 32 32 3,000 8,265E-05 2,72E-03 ! angiogenesis GO:0001525 65 64 4,000 1,004E-04 3,247E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 13 13 2,000 1,042E-04 3,31E-03 ! regulation of endothelial cell migration GO:0010594 13 13 2,000 1,042E-04 3,254E-03 ! response to endoplasmic reticulum stress GO:0034976 13 13 2,000 1,042E-04 3,2E-03 ! tissue homeostasis GO:0001894 13 13 2,000 1,042E-04 3,147E-03 GO:0048871|multicellular organismal homeostasis, ! protein tetramerization GO:0051262 13 13 2,000 1,042E-04 3,097E-03 ! regulation of angiogenesis GO:0045765 35 34 3,000 1,054E-04 3,084E-03 ! regulation of MAP kinase activity GO:0043405 67 66 4,000 1,164E-04 3,352E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 35 35 3,000 1,184E-04 3,357E-03 ! striated muscle tissue development GO:0014706 69 67 4,000 1,251E-04 3,493E-03 ! positive regulation of epithelial cell proliferation GO:0050679 14 14 2,000 1,319E-04 3,628E-03 ! regulation of transcription factor activity GO:0051090 38 37 3,000 1,477E-04 4,003E-03 GO:0090046|regulation of transcription regulator activity, ! positive regulation of transport GO:0051050 71 70 4,000 1,542E-04 4,118E-03 ! muscle tissue development GO:0060537 72 70 4,000 1,542E-04 4,059E-03 ! insulin receptor signaling pathway GO:0008286 17 15 2,000 1,64E-04 4,257E-03 ! ER-nuclear signaling pathway GO:0006984 15 15 2,000 1,64E-04 4,198E-03 ! response to starvation GO:0042594 15 15 2,000 1,64E-04 4,141E-03 ! regulation of production of molecular mediator of immune response GO:0002700 15 15 2,000 1,64E-04 4,085E-03 ! lymphocyte differentiation GO:0030098 39 39 3,000 1,82E-04 4,471E-03 ! cellular response to nutrient levels GO:0031669 16 16 2,000 2,008E-04 4,869E-03 ! regulation of fibroblast proliferation GO:0048145 17 17 2,000 2,426E-04 5,806E-03 ! embryonic organ development GO:0048568 17 17 2,000 2,426E-04 5,731E-03 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 42 42 3,000 2,436E-04 5,683E-03 ! regulation of cellular catabolic process GO:0031329 18 18 2,000 2,895E-04 6,67E-03 ! cellular response to extracellular stimulus GO:0031668 18 18 2,000 2,895E-04 6,588E-03 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 45 44 3,000 2,922E-04 6,568E-03 ! tube development GO:0035295 83 81 4,000 3,07E-04 6,816E-03 ! regulation of DNA binding GO:0051101 47 45 3,000 3,19E-04 6,999E-03 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 46 45 3,000 3,19E-04 6,916E-03 ! regulation of endothelial cell proliferation GO:0001936 19 19 2,000 3,42E-04 7,33E-03 ! regulation of protein stability GO:0031647 19 19 2,000 3,42E-04 7,246E-03 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 47 46 3,000 3,475E-04 7,277E-03 ! positive regulation of ligase activity GO:0051351 47 46 3,000 3,475E-04 7,195E-03 ! regulation of cellular localization GO:0060341 86 85 4,000 3,843E-04 7,871E-03 ! positive regulation of gene-specific transcription GO:0043193 20 20 2,000 4,003E-04 8,107E-03 ! regulation of anatomical structure morphogenesis GO:0022603 90 86 4,000 4,058E-04 8,129E-03 ! regulation of ubiquitin-protein ligase activity GO:0051438 49 48 3,000 4,098E-04 8,121E-03 ! leukocyte differentiation GO:0002521 50 49 3,000 4,438E-04 8,701E-03 ! regulation of ligase activity GO:0051340 50 49 3,000 4,438E-04 8,61E-03 ! spliceosome assembly GO:0000245 22 21 2,000 4,646E-04 8,919E-03 ! cellular response to insulin stimulus GO:0032869 23 21 2,000 4,646E-04 8,827E-03 ! negative regulation of protein transport GO:0051224 21 21 2,000 4,646E-04 8,737E-03 ! regulation of DNA metabolic process GO:0051052 51 50 3,000 4,798E-04 8,932E-03 ! T cell activation GO:0042110 51 50 3,000 4,798E-04 8,842E-03 ! anatomical structure homeostasis GO:0060249 51 50 3,000 4,798E-04 8,755E-03 ! negative regulation of cell cycle GO:0045786 92 91 4,000 5,27E-04 9,522E-03 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 5 5 1,000 5,312E-04 9,504E-03 ! hemoglobin biosynthetic process GO:0042541 5 5 1,000 5,312E-04 9,413E-03 ! positive regulation of B cell proliferation GO:0030890 5 5 1,000 5,312E-04 9,323E-03 ! mRNA stabilization GO:0048255 5 5 1,000 5,312E-04 9,235E-03 GO:0043489|RNA stabilization, ! dopamine receptor signaling pathway GO:0007212 5 5 1,000 5,312E-04 9,149E-03 ! heart looping GO:0001947 5 5 1,000 5,312E-04 9,064E-03 ! thymic T cell selection GO:0045061 5 5 1,000 5,312E-04 8,981E-03 ! regulation of cardiac muscle hypertrophy GO:0010611 5 5 1,000 5,312E-04 8,899E-03 GO:0010612|regulation of cardiac muscle adaptation, GO:0014743|regulation of muscle hypertrophy, GO:0043502|regulation of muscle adaptation, ! regulation of phospholipase A2 activity GO:0032429 5 5 1,000 5,312E-04 8,819E-03 ! receptor clustering GO:0043113 5 5 1,000 5,312E-04 8,74E-03 ! actin cytoskeleton reorganization GO:0031532 5 5 1,000 5,312E-04 8,663E-03 ! retinol metabolic process GO:0042572 5 5 1,000 5,312E-04 8,587E-03 ! cellular glucose homeostasis GO:0001678 5 5 1,000 5,312E-04 8,512E-03 ! regulation of vascular endothelial growth factor production GO:0010574 5 5 1,000 5,312E-04 8,439E-03 ! protein heterooligomerization GO:0051291 5 5 1,000 5,312E-04 8,367E-03 ! positive regulation of peptide secretion GO:0002793 5 5 1,000 5,312E-04 8,296E-03 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 5 5 1,000 5,312E-04 8,226E-03 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 5 5 1,000 5,312E-04 8,158E-03 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 5 5 1,000 5,312E-04 8,09E-03 ! negative regulation of focal adhesion formation GO:0051895 6 5 1,000 5,312E-04 8,024E-03 ! positive regulation of monooxygenase activity GO:0032770 5 5 1,000 5,312E-04 7,959E-03 ! T cell lineage commitment GO:0002360 5 5 1,000 5,312E-04 7,895E-03 ! positive regulation of immunoglobulin mediated immune response GO:0002891 5 5 1,000 5,312E-04 7,831E-03 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of hormone metabolic process GO:0032350 5 5 1,000 5,312E-04 7,769E-03 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 5 5 1,000 5,312E-04 7,708E-03 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 5 5 1,000 5,312E-04 7,648E-03 GO:0002820|negative regulation of adaptive immune response, ! peptidyl-lysine modification GO:0018205 5 5 1,000 5,312E-04 7,589E-03 ! negative regulation of neuroblast proliferation GO:0007406 5 5 1,000 5,312E-04 7,53E-03 ! regulation of isotype switching GO:0045191 5 5 1,000 5,312E-04 7,473E-03 ! glutathione biosynthetic process GO:0006750 5 5 1,000 5,312E-04 7,416E-03 ! positive regulation of erythrocyte differentiation GO:0045648 5 5 1,000 5,312E-04 7,36E-03 ! positive regulation of blood vessel endothelial cell migration GO:0043536 5 5 1,000 5,312E-04 7,305E-03 ! muscle adaptation GO:0043500 5 5 1,000 5,312E-04 7,251E-03 ! B cell receptor signaling pathway GO:0050853 5 5 1,000 5,312E-04 7,198E-03 ! positive regulation of transcription factor activity GO:0051091 22 22 2,000 5,351E-04 7,199E-03 GO:0090047|positive regulation of transcription regulator activity, ! positive regulation of DNA metabolic process GO:0051054 23 22 2,000 5,351E-04 7,147E-03 ! negative regulation of multicellular organismal process GO:0051241 55 54 3,000 6,446E-04 8,547E-03 ! regulation of T cell proliferation GO:0042129 25 25 2,000 7,868E-04 0,01035771 ! positive regulation of DNA binding GO:0043388 26 25 2,000 7,868E-04 0,01028425 ! negative regulation of immune system process GO:0002683 25 25 2,000 7,868E-04 0,01021183 ! positive regulation of cytokine production GO:0001819 25 25 2,000 7,868E-04 0,01014042 ! regulation of binding GO:0051098 60 57 3,000 7,921E-04 0,01013767 ! N-terminal protein amino acid modification GO:0031365 6 6 1,000 7,93E-04 0,01007885 GO:0018409|peptide or protein amino-terminal blocking, ! virus-host interaction GO:0019048 6 6 1,000 7,93E-04 0,01000981 ! regulation of S phase GO:0033261 6 6 1,000 7,93E-04 9,942E-03 ! regulation of B cell proliferation GO:0030888 6 6 1,000 7,93E-04 9,875E-03 ! retina development in camera-type eye GO:0060041 6 6 1,000 7,93E-04 9,808E-03 ! cartilage condensation GO:0001502 7 6 1,000 7,93E-04 9,743E-03 ! regulation of positive chemotaxis GO:0050926 6 6 1,000 7,93E-04 9,678E-03 GO:0050927|positive regulation of positive chemotaxis, ! positive regulation of transcription factor import into nucleus GO:0042993 6 6 1,000 7,93E-04 9,615E-03 ! negative regulation of protein amino acid phosphorylation GO:0001933 6 6 1,000 7,93E-04 9,552E-03 ! L-serine metabolic process GO:0006563 6 6 1,000 7,93E-04 9,49E-03 ! negative regulation of T cell proliferation GO:0042130 6 6 1,000 7,93E-04 9,429E-03 GO:0070667|negative regulation of mast cell proliferation, ! regulation of vascular permeability GO:0043114 6 6 1,000 7,93E-04 9,368E-03 ! peptidyl-serine phosphorylation GO:0018105 6 6 1,000 7,93E-04 9,308E-03 ! regulation of bone resorption GO:0045124 6 6 1,000 7,93E-04 9,25E-03 ! G1 DNA damage checkpoint GO:0031571 6 6 1,000 7,93E-04 9,191E-03 ! positive regulation of T cell mediated immunity GO:0002711 6 6 1,000 7,93E-04 9,134E-03 ! regulation of T cell differentiation in the thymus GO:0033081 6 6 1,000 7,93E-04 9,077E-03 ! genitalia development GO:0048806 6 6 1,000 7,93E-04 9,021E-03 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 6 6 1,000 7,93E-04 8,966E-03 ! phosphoinositide 3-kinase cascade GO:0014065 6 6 1,000 7,93E-04 8,911E-03 ! regulation of focal adhesion formation GO:0051893 7 6 1,000 7,93E-04 8,857E-03 ! nitric oxide mediated signal transduction GO:0007263 6 6 1,000 7,93E-04 8,804E-03 ! serine family amino acid biosynthetic process GO:0009070 6 6 1,000 7,93E-04 8,751E-03 ! regulation of embryonic development GO:0045995 6 6 1,000 7,93E-04 8,699E-03 ! negative regulation of immune effector process GO:0002698 6 6 1,000 7,93E-04 8,648E-03 ! localization within membrane GO:0051668 6 6 1,000 7,93E-04 8,597E-03 ! muscle organ development GO:0007517 102 100 4,000 8,115E-04 8,746E-03 ! hemopoiesis GO:0030097 104 100 4,000 8,115E-04 8,695E-03 ! positive regulation of binding GO:0051099 27 26 2,000 8,848E-04 9,426E-03 ! regulation of T cell differentiation GO:0045580 26 26 2,000 8,848E-04 9,372E-03 ! response to insulin stimulus GO:0032868 28 26 2,000 8,848E-04 9,318E-03 ! peptidyl-amino acid modification GO:0018193 61 59 3,000 9,027E-04 9,453E-03 ! protein polymerization GO:0051258 65 60 3,000 9,62E-04 0,0100165 ! proteasomal protein catabolic process GO:0010498 62 61 3,000 1,024E-03 0,01060129 GO:0043161|proteasomal ubiquitin-dependent protein catabolic process, ! regulation of protein amino acid phosphorylation GO:0001932 62 61 3,000 1,024E-03 0,01054207 ! regulation of mast cell proliferation GO:0070666 28 28 2,000 1,103E-03 0,01129627 ! cartilage development GO:0051216 29 28 2,000 1,103E-03 0,01123386 ! regulation of chemokine production GO:0032642 7 7 1,000 1,105E-03 0,0111885 ! hemoglobin metabolic process GO:0020027 7 7 1,000 1,105E-03 0,01112736 ! negative regulation of lymphocyte proliferation GO:0050672 7 7 1,000 1,105E-03 0,01106689 GO:0032945|negative regulation of mononuclear cell proliferation, GO:0070664|negative regulation of leukocyte proliferation, ! response to X-ray GO:0010165 7 7 1,000 1,105E-03 0,01100707 ! regulation of intracellular pH GO:0051453 7 7 1,000 1,105E-03 0,01094789 ! response to gamma radiation GO:0010332 8 7 1,000 1,105E-03 0,01088934 ! negative regulation of cell-substrate adhesion GO:0010812 8 7 1,000 1,105E-03 0,01083142 GO:0001953|negative regulation of cell-matrix adhesion, ! regulation of mRNA stability GO:0043488 7 7 1,000 1,105E-03 0,01077411 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 7 7 1,000 1,105E-03 0,01071741 ! T cell receptor signaling pathway GO:0050852 7 7 1,000 1,105E-03 0,0106613 ! negative regulation of T cell activation GO:0050868 7 7 1,000 1,105E-03 0,01060577 ! regulation of epithelial cell proliferation GO:0050678 29 29 2,000 1,224E-03 0,01168986 ! regulation of lymphocyte proliferation GO:0050670 29 29 2,000 1,224E-03 0,01162961 GO:0032944|regulation of mononuclear cell proliferation, GO:0070663|regulation of leukocyte proliferation, ! response to UV GO:0009411 29 29 2,000 1,224E-03 0,01156997 ! regulation of response to external stimulus GO:0032101 65 64 3,000 1,226E-03 0,01153212 ! activation of phospholipase C activity GO:0007202 30 30 2,000 1,353E-03 0,01265881 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of response to external stimulus GO:0032103 30 30 2,000 1,353E-03 0,01259488 ! vascular process in circulatory system GO:0003018 31 30 2,000 1,353E-03 0,01253159 ! positive regulation of cell killing GO:0031343 8 8 1,000 1,466E-03 0,01351106 ! negative regulation of bone remodeling GO:0046851 8 8 1,000 1,466E-03 0,01344385 ! T cell selection GO:0045058 8 8 1,000 1,466E-03 0,01337729 ! sex determination GO:0007530 8 8 1,000 1,466E-03 0,01331139 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 8 8 1,000 1,466E-03 0,01324614 ! regulation of T cell mediated immunity GO:0002709 8 8 1,000 1,466E-03 0,01318153 ! negative regulation of blood coagulation GO:0030195 9 8 1,000 1,466E-03 0,01311754 ! peptide biosynthetic process GO:0043043 9 8 1,000 1,466E-03 0,01305417 ! peptidyl-serine modification GO:0018209 8 8 1,000 1,466E-03 0,01299141 ! positive regulation of leukocyte migration GO:0002687 8 8 1,000 1,466E-03 0,01292925 ! regulation of RNA stability GO:0043487 8 8 1,000 1,466E-03 0,01286768 ! release of cytochrome c from mitochondria GO:0001836 9 8 1,000 1,466E-03 0,0128067 ! cytoplasmic sequestering of protein GO:0051220 8 8 1,000 1,466E-03 0,01274629 ! positive regulation of phospholipase activity GO:0010518 31 31 2,000 1,49E-03 0,01289492 ! regulation of DNA replication GO:0006275 32 31 2,000 1,49E-03 0,01283467 ! ribonucleoprotein complex assembly GO:0022618 32 31 2,000 1,49E-03 0,01277497 ! negative regulation of cell motion GO:0051271 31 31 2,000 1,49E-03 0,01271583 ! response to nutrient levels GO:0031667 69 69 3,000 1,624E-03 0,01379184 ! regulation of phospholipase activity GO:0010517 32 32 2,000 1,636E-03 0,01383025 ! regulation of lymphocyte differentiation GO:0045619 32 32 2,000 1,636E-03 0,0137671 ! positive regulation of lipase activity GO:0060193 32 32 2,000 1,636E-03 0,01370452 ! wound healing GO:0042060 74 70 3,000 1,713E-03 0,01428503 ! negative regulation of signal transduction GO:0009968 71 71 3,000 1,805E-03 0,01498793 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 9 9 1,000 1,876E-03 0,01550593 ! positive regulation of protein import into nucleus GO:0042307 9 9 1,000 1,876E-03 0,0154367 ! T cell differentiation in the thymus GO:0033077 9 9 1,000 1,876E-03 0,0153681 ! regulation of cellular pH GO:0030641 9 9 1,000 1,876E-03 0,01530009 ! histone acetylation GO:0016573 9 9 1,000 1,876E-03 0,01523269 ! regulation of immunoglobulin mediated immune response GO:0002889 9 9 1,000 1,876E-03 0,01516588 GO:0002712|regulation of B cell mediated immunity, ! negative regulation of tissue remodeling GO:0034104 9 9 1,000 1,876E-03 0,01509966 ! regulation of leukocyte migration GO:0002685 9 9 1,000 1,876E-03 0,01503401 ! regulation of leukocyte mediated cytotoxicity GO:0001910 9 9 1,000 1,876E-03 0,01496892 ! regulation of blood vessel endothelial cell migration GO:0043535 9 9 1,000 1,876E-03 0,0149044 ! defense response to virus GO:0051607 9 9 1,000 1,876E-03 0,01484044 ! positive regulation of hydrolase activity GO:0051345 72 72 3,000 1,901E-03 0,01497409 ! response to extracellular stimulus GO:0009991 72 72 3,000 1,901E-03 0,01491037 ! regulation of protein catabolic process GO:0042176 35 34 2,000 1,953E-03 0,0152531 ! response to peptide hormone stimulus GO:0043434 36 34 2,000 1,953E-03 0,01518875 ! positive regulation of phosphorylation GO:0042327 35 35 2,000 2,125E-03 0,01645694 ! regulation of immune effector process GO:0002697 35 35 2,000 2,125E-03 0,01638809 ! positive regulation of phosphorus metabolic process GO:0010562 36 36 2,000 2,306E-03 0,01771095 GO:0045937|positive regulation of phosphate metabolic process, ! regulation of lipase activity GO:0060191 36 36 2,000 2,306E-03 0,01763746 ! negative regulation of cell communication GO:0010648 76 76 3,000 2,32E-03 0,01766801 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 10 10 1,000 2,334E-03 0,01770296 ! regulation of cell killing GO:0031341 10 10 1,000 2,334E-03 0,01763041 ! negative regulation of nucleocytoplasmic transport GO:0046823 10 10 1,000 2,334E-03 0,01755844 ! inositol metabolic process GO:0006020 10 10 1,000 2,334E-03 0,01748707 ! auditory receptor cell differentiation GO:0042491 10 10 1,000 2,334E-03 0,01741627 ! apoptotic mitochondrial changes GO:0008637 11 10 1,000 2,334E-03 0,01734604 ! neuromuscular junction development GO:0007528 10 10 1,000 2,334E-03 0,01727638 ! negative regulation of immune response GO:0050777 10 10 1,000 2,334E-03 0,01720728 ! regulation of B cell differentiation GO:0045577 10 10 1,000 2,334E-03 0,01713872 ! mRNA splice site selection GO:0006376 11 10 1,000 2,334E-03 0,01707071 ! regulation of erythrocyte differentiation GO:0045646 10 10 1,000 2,334E-03 0,01700324 ! epithelial to mesenchymal transition GO:0001837 10 10 1,000 2,334E-03 0,01693629 ! embryonic organ morphogenesis GO:0048562 10 10 1,000 2,334E-03 0,01686988 ! positive regulation of neuron apoptosis GO:0043525 10 10 1,000 2,334E-03 0,01680398 ! negative regulation of homeostatic process GO:0032845 10 10 1,000 2,334E-03 0,01673859 ! antigen receptor-mediated signaling pathway GO:0050851 10 10 1,000 2,334E-03 0,01667372 ! negative regulation of coagulation GO:0050819 11 10 1,000 2,334E-03 0,01660934 ! protein stabilization GO:0050821 10 10 1,000 2,334E-03 0,01654546 ! cell morphogenesis involved in differentiation GO:0000904 82 77 3,000 2,434E-03 0,01718581 ! negative regulation of protein kinase activity GO:0006469 37 37 2,000 2,497E-03 0,0175636 ! negative regulation of growth GO:0045926 37 37 2,000 2,497E-03 0,01749682 ! regulation of protein modification process GO:0031399 79 78 3,000 2,551E-03 0,01781186 ! microtubule-based movement GO:0007018 82 78 3,000 2,551E-03 0,01774465 ! positive regulation of protein kinase cascade GO:0010740 79 78 3,000 2,551E-03 0,01767794 ! urogenital system development GO:0001655 38 38 2,000 2,697E-03 0,01861482 ! negative regulation of kinase activity GO:0033673 38 38 2,000 2,697E-03 0,01854536 ! axon guidance GO:0007411 39 38 2,000 2,697E-03 0,01847642 ! neuron projection development GO:0031175 85 80 3,000 2,798E-03 0,01910173 ! positive regulation of hormone secretion GO:0046887 11 11 1,000 2,839E-03 0,01930961 ! signal complex assembly GO:0007172 11 11 1,000 2,839E-03 0,01923862 ! endothelial cell migration GO:0043542 11 11 1,000 2,839E-03 0,01916815 ! protein amino acid methylation GO:0006479 11 11 1,000 2,839E-03 0,01909819 GO:0008213|protein amino acid alkylation, ! protein amino acid acetylation GO:0006473 11 11 1,000 2,839E-03 0,01902875 ! T cell proliferation GO:0042098 11 11 1,000 2,839E-03 0,0189598 ! regulation of transmembrane transporter activity GO:0022898 11 11 1,000 2,839E-03 0,01889135 GO:0032412|regulation of ion transmembrane transporter activity, GO:0032409|regulation of transporter activity, ! activation of MAPKK activity GO:0000186 12 11 1,000 2,839E-03 0,0188234 ! digestive system process GO:0022600 11 11 1,000 2,839E-03 0,01875593 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 11 11 1,000 2,839E-03 0,01868895 ! G1/S transition checkpoint GO:0031575 12 11 1,000 2,839E-03 0,01862244 ! positive regulation of alpha-beta T cell activation GO:0046635 11 11 1,000 2,839E-03 0,0185564 ! interaction with host GO:0051701 11 11 1,000 2,839E-03 0,01849083 ! regulation of ARF GTPase activity GO:0032312 11 11 1,000 2,839E-03 0,01842572 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 11 11 1,000 2,839E-03 0,01836107 ! vitamin transport GO:0051180 11 11 1,000 2,839E-03 0,01829687 ! muscle maintenance GO:0046716 12 11 1,000 2,839E-03 0,01823312 ! vitamin A metabolic process GO:0006776 11 11 1,000 2,839E-03 0,01816981 ! endocrine process GO:0050886 11 11 1,000 2,839E-03 0,01810694 GO:0001990|regulation of systemic arterial blood pressure by hormone, ! negative regulation of lymphocyte activation GO:0051250 11 11 1,000 2,839E-03 0,0180445 ! activation of MAPK activity GO:0000187 39 39 2,000 2,906E-03 0,01840684 ! protein oligomerization GO:0051259 39 39 2,000 2,906E-03 0,0183438 ! MAPKKK cascade GO:0000165 82 81 3,000 2,928E-03 0,01841637 ! lymphocyte activation GO:0046649 82 81 3,000 2,928E-03 0,01835373 ! negative regulation of transferase activity GO:0051348 40 40 2,000 3,126E-03 0,01952762 ! positive regulation of protein catabolic process GO:0045732 12 12 1,000 3,391E-03 0,02111417 ! positive regulation of angiogenesis GO:0045766 12 12 1,000 3,391E-03 0,02104308 ! post-Golgi vesicle-mediated transport GO:0006892 12 12 1,000 3,391E-03 0,02097246 ! collagen metabolic process GO:0032963 12 12 1,000 3,391E-03 0,02090232 ! positive regulation of endocytosis GO:0045807 12 12 1,000 3,391E-03 0,02083265 ! retinoid metabolic process GO:0001523 12 12 1,000 3,391E-03 0,02076343 GO:0016101|diterpenoid metabolic process, ! regulation of insulin secretion GO:0050796 12 12 1,000 3,391E-03 0,02069468 ! regulation of alpha-beta T cell activation GO:0046634 12 12 1,000 3,391E-03 0,02062638 ! renal system process GO:0003014 12 12 1,000 3,391E-03 0,02055853 ! fibroblast growth factor receptor signaling pathway GO:0008543 12 12 1,000 3,391E-03 0,02049113 ! somitogenesis GO:0001756 13 12 1,000 3,391E-03 0,02042416 ! positive regulation of adaptive immune response GO:0002821 12 12 1,000 3,391E-03 0,02035763 ! fat-soluble vitamin metabolic process GO:0006775 12 12 1,000 3,391E-03 0,02029154 ! cellular monovalent inorganic cation homeostasis GO:0030004 12 12 1,000 3,391E-03 0,02022587 ! positive regulation of response to stimulus GO:0048584 86 85 3,000 3,487E-03 0,02072862 ! negative regulation of ligase activity GO:0051352 43 42 2,000 3,594E-03 0,02129997 GO:0051444|negative regulation of ubiquitin-protein ligase activity, GO:0051436|negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 43 43 2,000 3,844E-03 0,02270574 ! positive regulation of DNA replication GO:0045740 14 13 1,000 3,989E-03 0,0234863 ! positive regulation of smooth muscle cell proliferation GO:0048661 13 13 1,000 3,989E-03 0,0234115 ! gluconeogenesis GO:0006094 13 13 1,000 3,989E-03 0,02333718 ! intra-Golgi vesicle-mediated transport GO:0006891 13 13 1,000 3,989E-03 0,02326333 ! negative regulation of protein modification process GO:0031400 13 13 1,000 3,989E-03 0,02318994 ! vasculogenesis GO:0001570 13 13 1,000 3,989E-03 0,02311702 ! regulation of DNA recombination GO:0000018 13 13 1,000 3,989E-03 0,02304455 ! mitochondrial membrane organization GO:0007006 13 13 1,000 3,989E-03 0,02297254 ! negative regulation of DNA replication GO:0008156 13 13 1,000 3,989E-03 0,02290097 ! multicellular organismal macromolecule metabolic process GO:0044259 13 13 1,000 3,989E-03 0,02282985 ! receptor metabolic process GO:0043112 14 13 1,000 3,989E-03 0,02275917 ! actin filament bundle formation GO:0051017 13 13 1,000 3,989E-03 0,02268893 ! negative regulation of protein catabolic process GO:0042177 13 13 1,000 3,989E-03 0,02261912 ! cell aging GO:0007569 13 13 1,000 3,989E-03 0,02254973 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 13 13 1,000 3,989E-03 0,02248077 ! negative regulation of protein kinase cascade GO:0010741 13 13 1,000 3,989E-03 0,02241223 ! regulation of peptide secretion GO:0002791 13 13 1,000 3,989E-03 0,02234411 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 14 13 1,000 3,989E-03 0,0222764 ! positive regulation of leukocyte mediated immunity GO:0002705 13 13 1,000 3,989E-03 0,0222091 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 13 13 1,000 3,989E-03 0,02214221 ! positive regulation of locomotion GO:0040017 13 13 1,000 3,989E-03 0,02207571 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, GO:0050920|regulation of chemotaxis, ! neural crest cell migration GO:0001755 14 13 1,000 3,989E-03 0,02200962 ! immunoglobulin production GO:0002377 13 13 1,000 3,989E-03 0,02194392 GO:0002440|production of molecular mediator of immune response, ! negative regulation of intracellular transport GO:0032387 13 13 1,000 3,989E-03 0,02187861 ! negative regulation of leukocyte activation GO:0002695 13 13 1,000 3,989E-03 0,02181369 ! regulation of cell-substrate adhesion GO:0010810 14 13 1,000 3,989E-03 0,02174915 GO:0001952|regulation of cell-matrix adhesion, ! terpenoid metabolic process GO:0006721 13 13 1,000 3,989E-03 0,02168499 ! camera-type eye morphogenesis GO:0048593 13 13 1,000 3,989E-03 0,02162121 ! inner ear receptor cell differentiation GO:0060113 13 13 1,000 3,989E-03 0,02155781 ! phosphoinositide-mediated signaling GO:0048015 45 45 2,000 4,374E-03 0,02357127 ! pyruvate metabolic process GO:0006090 14 14 1,000 4,632E-03 0,02488601 ! cellular iron ion homeostasis GO:0006879 14 14 1,000 4,632E-03 0,02481367 ! protein amino acid acylation GO:0043543 14 14 1,000 4,632E-03 0,02474174 ! mechanoreceptor differentiation GO:0042490 14 14 1,000 4,632E-03 0,02467024 ! immune response-activating cell surface receptor signaling pathway GO:0002429 14 14 1,000 4,632E-03 0,02459914 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! response to retinoic acid GO:0032526 14 14 1,000 4,632E-03 0,02452845 GO:0033189|response to vitamin A, ! negative regulation of phosphorus metabolic process GO:0010563 14 14 1,000 4,632E-03 0,02445817 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of behavior GO:0050795 14 14 1,000 4,632E-03 0,02438829 ! base-excision repair GO:0006284 14 14 1,000 4,632E-03 0,02431881 ! regulation of vasoconstriction GO:0019229 14 14 1,000 4,632E-03 0,02424972 ! regulation of blood coagulation GO:0030193 15 14 1,000 4,632E-03 0,02418103 ! positive regulation of inflammatory response GO:0050729 14 14 1,000 4,632E-03 0,02411272 ! cyclic-nucleotide-mediated signaling GO:0019935 46 46 2,000 4,655E-03 0,02416654 ! cellular response to hormone stimulus GO:0032870 48 46 2,000 4,655E-03 0,02409865 ! actin filament organization GO:0007015 50 48 2,000 5,249E-03 0,02709809 ! protein import into nucleus, translocation GO:0000060 15 15 1,000 5,319E-03 0,02738161 ! positive regulation of fibroblast proliferation GO:0048146 15 15 1,000 5,319E-03 0,02730534 ! response to vitamin GO:0033273 15 15 1,000 5,319E-03 0,02722949 ! regulation of transcription factor import into nucleus GO:0042990 15 15 1,000 5,319E-03 0,02715406 ! response to ionizing radiation GO:0010212 16 15 1,000 5,319E-03 0,02707905 ! glutathione metabolic process GO:0006749 16 15 1,000 5,319E-03 0,02700445 ! positive regulation of B cell activation GO:0050871 15 15 1,000 5,319E-03 0,02693026 ! positive regulation of myeloid cell differentiation GO:0045639 16 15 1,000 5,319E-03 0,02685648 ! negative regulation of transcription factor activity GO:0043433 16 15 1,000 5,319E-03 0,0267831 GO:0090048|negative regulation of transcription regulator activity, ! negative regulation of cell activation GO:0050866 15 15 1,000 5,319E-03 0,02671013 ! positive regulation of immune effector process GO:0002699 15 15 1,000 5,319E-03 0,02663754 ! regulation of cell growth GO:0001558 97 96 3,000 5,389E-03 0,02691588 ! ossification GO:0001503 50 49 2,000 5,562E-03 0,027707 GO:0060348|bone development, ! cell cycle arrest GO:0007050 49 49 2,000 5,562E-03 0,02763232 ! skeletal muscle tissue development GO:0007519 50 49 2,000 5,562E-03 0,02755804 GO:0060538|skeletal muscle organ development, ! posttranscriptional regulation of gene expression GO:0010608 98 98 3,000 5,797E-03 0,02864219 ! negative regulation of transport GO:0051051 51 50 2,000 5,887E-03 0,02900938 ! anterior/posterior pattern formation GO:0009952 51 50 2,000 5,887E-03 0,02893202 ! anti-apoptosis GO:0006916 100 99 3,000 6,008E-03 0,02945003 ! negative regulation of adenylate cyclase activity GO:0007194 16 16 1,000 6,05E-03 0,02957592 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! spliceosomal snRNP biogenesis GO:0000387 16 16 1,000 6,05E-03 0,02949768 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 16 16 1,000 6,05E-03 0,02941985 ! segmentation GO:0035282 17 16 1,000 6,05E-03 0,02934243 ! iron ion homeostasis GO:0055072 16 16 1,000 6,05E-03 0,02926541 ! lymphocyte proliferation GO:0046651 16 16 1,000 6,05E-03 0,0291888 ! regulation of systemic arterial blood pressure GO:0003073 17 16 1,000 6,05E-03 0,02911259 ! positive regulation of MAPKKK cascade GO:0043410 17 16 1,000 6,05E-03 0,02903678 ! polyol metabolic process GO:0019751 16 16 1,000 6,05E-03 0,02896136 ! serine family amino acid metabolic process GO:0009069 16 16 1,000 6,05E-03 0,02888633 ! response to xenobiotic stimulus GO:0009410 16 16 1,000 6,05E-03 0,02881169 ! regulation of coagulation GO:0050818 17 16 1,000 6,05E-03 0,02873743 ! negative regulation of transcription from RNA polymerase II promoter GO:0000122 103 100 3,000 6,225E-03 0,02949173 ! response to light stimulus GO:0009416 53 52 2,000 6,569E-03 0,03104393 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 17 17 1,000 6,824E-03 0,03216676 ! regulation of smooth muscle cell proliferation GO:0048660 17 17 1,000 6,824E-03 0,0320847 ! positive regulation of cell adhesion GO:0045785 17 17 1,000 6,824E-03 0,03200306 ! myelination GO:0042552 17 17 1,000 6,824E-03 0,03192183 ! regulation of transmembrane transport GO:0034762 17 17 1,000 6,824E-03 0,03184102 ! leukocyte adhesion GO:0007159 17 17 1,000 6,824E-03 0,03176061 ! neural crest cell development GO:0014032 19 17 1,000 6,824E-03 0,03168061 GO:0014033|neural crest cell differentiation, ! negative regulation of cell development GO:0010721 18 17 1,000 6,824E-03 0,03160101 GO:0050768|negative regulation of neurogenesis, ! immune response-activating signal transduction GO:0002757 17 17 1,000 6,824E-03 0,03152181 GO:0002764|immune response-regulating signal transduction, ! positive regulation of protein secretion GO:0050714 17 17 1,000 6,824E-03 0,03144301 ! regulation of T cell activation GO:0050863 53 53 2,000 6,927E-03 0,0318384 ! protein amino acid dephosphorylation GO:0006470 55 54 2,000 7,297E-03 0,03345355 ! mononuclear cell proliferation GO:0032943 18 18 1,000 7,641E-03 0,03494454 GO:0070661|leukocyte proliferation, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 18 18 1,000 7,641E-03 0,03485804 ! negative regulation of DNA binding GO:0043392 19 18 1,000 7,641E-03 0,03477197 ! hexose biosynthetic process GO:0019319 18 18 1,000 7,641E-03 0,03468633 ! B cell differentiation GO:0030183 18 18 1,000 7,641E-03 0,0346011 ! ensheathment of neurons GO:0007272 18 18 1,000 7,641E-03 0,0345163 GO:0008366|axon ensheathment, ! negative regulation of catabolic process GO:0009895 18 18 1,000 7,641E-03 0,0344319 ! symbiosis, encompassing mutualism through parasitism GO:0044403 18 18 1,000 7,641E-03 0,03434792 ! in utero embryonic development GO:0001701 55 55 2,000 7,678E-03 0,03442987 ! regulation of cell adhesion GO:0030155 56 55 2,000 7,678E-03 0,03434631 ! reproductive developmental process GO:0003006 56 56 2,000 8,071E-03 0,03601551 ! DNA damage checkpoint GO:0000077 19 19 1,000 8,5E-03 0,03783881 ! negative regulation of DNA metabolic process GO:0051053 19 19 1,000 8,5E-03 0,03774764 ! regulation of pH GO:0006885 19 19 1,000 8,5E-03 0,0376569 ! positive regulation of T cell proliferation GO:0042102 19 19 1,000 8,5E-03 0,03756659 ! multicellular organismal metabolic process GO:0044236 19 19 1,000 8,5E-03 0,03747672 ! peptidyl-tyrosine phosphorylation GO:0018108 20 19 1,000 8,5E-03 0,03738728 ! cellular response to oxidative stress GO:0034599 19 19 1,000 8,5E-03 0,03729826 ! regulation of lymphocyte mediated immunity GO:0002706 19 19 1,000 8,5E-03 0,03720966 ! positive regulation of T cell differentiation GO:0045582 19 19 1,000 8,5E-03 0,03712149 ! peripheral nervous system development GO:0007422 19 19 1,000 8,5E-03 0,03703373 ! eye morphogenesis GO:0048592 19 19 1,000 8,5E-03 0,03694639 ! regulation of cell shape GO:0008360 21 19 1,000 8,5E-03 0,03685946 ! placenta development GO:0001890 19 19 1,000 8,5E-03 0,03677293 ! dephosphorylation GO:0016311 60 59 2,000 9,319E-03 0,0402232 ! negative regulation of cell adhesion GO:0007162 21 20 1,000 9,4E-03 0,04047636 ! negative regulation of binding GO:0051100 21 20 1,000 9,4E-03 0,04038201 ! peptidyl-tyrosine modification GO:0018212 21 20 1,000 9,4E-03 0,04028809 ! monosaccharide biosynthetic process GO:0046364 20 20 1,000 9,4E-03 0,04019462 ! regulation of B cell activation GO:0050864 20 20 1,000 9,4E-03 0,04010158 ! G1/S transition of mitotic cell cycle GO:0000082 21 21 1,000 0,01034038 0,04401228 ! mammary gland development GO:0030879 23 21 1,000 0,01034038 0,04391087 ! DNA integrity checkpoint GO:0031570 21 21 1,000 0,01034038 0,04380993 ! regulation of protein import into nucleus GO:0042306 21 21 1,000 0,01034038 0,04370944 ! regulation of leukocyte mediated immunity GO:0002703 21 21 1,000 0,01034038 0,04360942 ! regulation of action potential in neuron GO:0019228 21 21 1,000 0,01034038 0,04350986 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 21 21 1,000 0,01034038 0,04341075 ! negative regulation of hydrolase activity GO:0051346 21 21 1,000 0,01034038 0,04331209 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 21 21 1,000 0,01034038 0,04321387 ! axonogenesis GO:0007409 66 62 2,000 0,01067473 0,04451025 ! regulation of cellular component biogenesis GO:0044087 63 62 2,000 0,01067473 0,04440978 ! regulation of lymphocyte activation GO:0051249 62 62 2,000 0,01067473 0,04430975 ! regulation of secretion GO:0051046 65 63 2,000 0,01115067 0,0461813 ! positive regulation of lymphocyte proliferation GO:0050671 22 22 1,000 0,0113209 0,04678122 GO:0032946|positive regulation of mononuclear cell proliferation, GO:0070665|positive regulation of leukocyte proliferation, GO:0070668|positive regulation of mast cell proliferation, ! embryonic skeletal system development GO:0048706 22 22 1,000 0,0113209 0,04667656 ! maintenance of protein location in cell GO:0032507 23 22 1,000 0,0113209 0,04657237 ! biopolymer methylation GO:0043414 22 22 1,000 0,0113209 0,04646865 GO:0032259|methylation, ! regulation of adaptive immune response GO:0002819 22 22 1,000 0,0113209 0,04636539 ! positive regulation of lymphocyte differentiation GO:0045621 22 22 1,000 0,0113209 0,04626258 ! positive regulation of protein metabolic process GO:0051247 64 64 2,000 0,01163874 0,0474562 ! positive regulation of cellular component organization GO:0051130 65 65 2,000 0,01213902 0,04938678 ! regulation of hormone secretion GO:0046883 23 23 1,000 0,01234078 0,05009704 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 23 23 1,000 0,01234078 0,04998694 ! mitotic cell cycle checkpoint GO:0007093 24 23 1,000 0,01234078 0,04987732 ! regulation of ARF protein signal transduction GO:0032012 23 23 1,000 0,01234078 0,04976818 ! positive regulation of growth GO:0045927 23 23 1,000 0,01234078 0,04965951 ! monovalent inorganic cation homeostasis GO:0055067 23 23 1,000 0,01234078 0,04955132 ! calcium-mediated signaling GO:0019722 23 23 1,000 0,01234078 0,0494436 ! cell projection assembly GO:0030031 25 23 1,000 0,01234078 0,04933635 ! negative regulation of protein metabolic process GO:0051248 66 66 2,000 0,01265154 0,05046923 ! cell morphogenesis involved in neuron differentiation GO:0048667 72 67 2,000 0,01317635 0,05244928 GO:0048812|neuron projection morphogenesis, GO:0048858|cell projection morphogenesis, ! Golgi vesicle transport GO:0048193 67 67 2,000 0,01317635 0,05233624 ! mitochondrial transport GO:0006839 24 24 1,000 0,01339939 0,05310771 ! regulation of action potential GO:0001508 24 24 1,000 0,01339939 0,05299374 ! cellular amino acid biosynthetic process GO:0008652 24 24 1,000 0,01339939 0,05288026 ! maintenance of protein location GO:0045185 25 24 1,000 0,01339939 0,05276727 ! glucan metabolic process GO:0044042 25 24 1,000 0,01339939 0,05265476 GO:0006073|cellular glucan metabolic process, GO:0005977|glycogen metabolic process, ! response to radiation GO:0009314 70 68 2,000 0,0137135 0,05377443 ! regionalization GO:0003002 70 69 2,000 0,01426303 0,05581054 ! regulation of leukocyte activation GO:0002694 69 69 2,000 0,01426303 0,05569229 ! endosome transport GO:0016197 25 25 1,000 0,01449614 0,05648285 ! alcohol biosynthetic process GO:0046165 25 25 1,000 0,01449614 0,05636369 ! development of primary female sexual characteristics GO:0046545 25 25 1,000 0,01449614 0,05624503 GO:0046660|female sex differentiation, ! regulation of endocytosis GO:0030100 25 25 1,000 0,01449614 0,05612687 ! cell part morphogenesis GO:0032990 75 70 2,000 0,01482497 0,05727971 ! regulation of cell activation GO:0050865 71 71 2,000 0,01539937 0,05937454 ! positive regulation of defense response GO:0031349 26 26 1,000 0,01563042 0,06013959 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 26 26 1,000 0,01563042 0,0600143 ! negative regulation of cell migration GO:0030336 26 26 1,000 0,01563042 0,05988953 ! induction of apoptosis by intracellular signals GO:0008629 26 26 1,000 0,01563042 0,05976528 ! double-strand break repair GO:0006302 27 26 1,000 0,01563042 0,05964154 ! regulation of protein secretion GO:0050708 26 26 1,000 0,01563042 0,05951831 ! regulation of blood vessel size GO:0050880 27 26 1,000 0,01563042 0,0593956 GO:0035150|regulation of tube size, ! maintenance of location in cell GO:0051651 27 26 1,000 0,01563042 0,05927338 ! synapse organization GO:0050808 26 26 1,000 0,01563042 0,05915167 ! sensory organ development GO:0007423 72 72 2,000 0,01598624 0,06037427 ! regulation of cytokine production GO:0001817 72 72 2,000 0,01598624 0,06025081 ! energy reserve metabolic process GO:0006112 28 27 1,000 0,01680164 0,06319472 ! learning or memory GO:0007611 28 27 1,000 0,01680164 0,06306602 ! cAMP-mediated signaling GO:0019933 27 27 1,000 0,01680164 0,06293784 ! peptide metabolic process GO:0006518 29 27 1,000 0,01680164 0,06281017 ! activation of caspase activity GO:0006919 27 27 1,000 0,01680164 0,06268303 ! mesenchymal cell development GO:0014031 29 27 1,000 0,01680164 0,06255639 GO:0060485|mesenchyme development, GO:0048762|mesenchymal cell differentiation, ! inner ear development GO:0048839 27 27 1,000 0,01680164 0,06243027 ! isoprenoid metabolic process GO:0006720 27 27 1,000 0,01680164 0,06230466 ! sulfur compound biosynthetic process GO:0044272 28 28 1,000 0,0180092 0,06664851 ! histone modification GO:0016570 28 28 1,000 0,0180092 0,06651495 ! positive regulation of multicellular organismal process GO:0051240 76 76 2,000 0,01845912 0,06804031 ! positive regulation of cell cycle GO:0045787 29 29 1,000 0,01925254 0,07082321 ! viral reproductive process GO:0022415 29 29 1,000 0,01925254 0,07068213 ! phosphoinositide metabolic process GO:0030384 29 29 1,000 0,01925254 0,07054161 ! covalent chromatin modification GO:0016569 29 29 1,000 0,01925254 0,07040164 ! regulation of immune response GO:0050776 78 78 2,000 0,01977109 0,07215468 ! positive regulation of peptidase activity GO:0010952 30 30 1,000 0,02053107 0,07478016 GO:0043280|positive regulation of caspase activity, ! positive regulation of protein amino acid phosphorylation GO:0001934 30 30 1,000 0,02053107 0,07463266 ! skeletal system morphogenesis GO:0048705 31 30 1,000 0,02053107 0,07448575 ! regulation of inflammatory response GO:0050727 30 30 1,000 0,02053107 0,07433941 ! cellular amino acid derivative biosynthetic process GO:0042398 31 30 1,000 0,02053107 0,07419365 ! skeletal muscle fiber development GO:0048741 31 31 1,000 0,02184423 0,07878455 ! B cell activation GO:0042113 31 31 1,000 0,02184423 0,07863068 ! aging GO:0007568 32 31 1,000 0,02184423 0,0784774 ! digestion GO:0007586 31 31 1,000 0,02184423 0,07832472 ! camera-type eye development GO:0043010 31 31 1,000 0,02184423 0,07817264 ! regulation of myeloid cell differentiation GO:0045637 32 31 1,000 0,02184423 0,07802114 ! negative regulation of cell growth GO:0030308 32 32 1,000 0,02319145 0,08267279 ! muscle fiber development GO:0048747 32 32 1,000 0,02319145 0,08251319 ! lipid modification GO:0030258 32 32 1,000 0,02319145 0,08235421 ! regulation of vesicle-mediated transport GO:0060627 33 32 1,000 0,02319145 0,08219584 ! kidney development GO:0001822 32 32 1,000 0,02319145 0,08203807 ! maintenance of location GO:0051235 33 32 1,000 0,02319145 0,08188091 ! negative regulation of cell size GO:0045792 33 33 1,000 0,02457217 0,0865899 ! amino acid transport GO:0006865 33 33 1,000 0,02457217 0,08642465 ! activation of protein kinase activity GO:0032147 35 33 1,000 0,02457217 0,08626003 ! regulation of neuron apoptosis GO:0043523 34 33 1,000 0,02457217 0,08609604 ! positive regulation of cell differentiation GO:0045597 87 85 2,000 0,0247613 0,08659408 ! regulation of bone remodeling GO:0046850 34 34 1,000 0,02598586 0,09070443 ! ear development GO:0043583 34 34 1,000 0,02598586 0,09053297 ! cellular polysaccharide metabolic process GO:0044264 35 34 1,000 0,02598586 0,09036215 ! coenzyme biosynthetic process GO:0009108 34 34 1,000 0,02598586 0,09019198 ! secondary metabolic process GO:0019748 34 34 1,000 0,02598586 0,09002245 ! negative regulation of response to stimulus GO:0048585 34 34 1,000 0,02598586 0,08985355 ! viral reproduction GO:0016032 34 34 1,000 0,02598586 0,08968528 ! regulation of cell morphogenesis GO:0022604 38 35 1,000 0,02743196 0,09449926 ! regulation of tissue remodeling GO:0034103 35 35 1,000 0,02743196 0,09432296 ! cellular di-, tri-valent inorganic cation homeostasis GO:0030005 89 89 2,000 0,02789134 0,0957239 ! oxygen and reactive oxygen species metabolic process GO:0006800 37 36 1,000 0,02890994 0,09903534 ! integrin-mediated signaling pathway GO:0007229 36 36 1,000 0,02890994 0,0988516 ! activation of immune response GO:0002253 36 36 1,000 0,02890994 0,09866855 ! coagulation GO:0050817 39 36 1,000 0,02890994 0,09848616 GO:0007596|blood coagulation, ! di-, tri-valent inorganic cation homeostasis GO:0055066 91 91 2,000 0,02953217 0,10042028 ! positive regulation of immune system process GO:0002684 92 92 2,000 0,0303715 0,1030841 ! regulation of adenylate cyclase activity GO:0045761 37 37 1,000 0,03041926 0,10305642 GO:0031279|regulation of cyclase activity, GO:0051339|regulation of lyase activity, ! response to drug GO:0042493 37 37 1,000 0,03041926 0,10286732 ! eye development GO:0001654 37 37 1,000 0,03041926 0,10267892 ! DNA damage response, signal transduction GO:0042770 37 37 1,000 0,03041926 0,10249121 ! adaptive immune response GO:0002250 37 37 1,000 0,03041926 0,10230418 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! positive regulation of secretion GO:0051047 39 38 1,000 0,0319594 0,1072881 ! cellular hormone metabolic process GO:0034754 39 38 1,000 0,0319594 0,10709303 ! cell-matrix adhesion GO:0007160 39 38 1,000 0,0319594 0,10689867 ! chromosome segregation GO:0007059 38 38 1,000 0,0319594 0,10670501 ! regulation of response to stress GO:0080134 97 94 2,000 0,03208788 0,10694027 ! pattern specification process GO:0007389 96 94 2,000 0,03208788 0,10674724 ! regulation of cAMP biosynthetic process GO:0030817 39 39 1,000 0,03352983 0,1113432 ! hemostasis GO:0007599 42 39 1,000 0,03352983 0,11114295 ! positive regulation of protein modification process GO:0031401 39 39 1,000 0,03352983 0,11094341 ! nucleotide-excision repair GO:0006289 40 39 1,000 0,03352983 0,11074458 ! cytokine-mediated signaling pathway GO:0019221 39 39 1,000 0,03352983 0,11054647 ! regulation of MAPKKK cascade GO:0043408 41 39 1,000 0,03352983 0,11034907 ! positive regulation of T cell activation GO:0050870 39 39 1,000 0,03352983 0,11015237 ! regulation of cAMP metabolic process GO:0030814 40 40 1,000 0,03513005 0,11520406 ! blood circulation GO:0008015 99 98 2,000 0,03567101 0,11677029 GO:0003013|circulatory system process, ! rRNA transcription GO:0009303 5 5 0,000 0,03652898 0,11936686 ! positive regulation of protein ubiquitination GO:0031398 5 5 0,000 0,03652898 0,11915559 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 5 5 0,000 0,03652898 0,11894507 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! neuron fate specification GO:0048665 5 5 0,000 0,03652898 0,11873529 ! reproductive cellular process GO:0048610 5 5 0,000 0,03652898 0,11852625 ! negative regulation of blood pressure GO:0045776 6 5 0,000 0,03652898 0,11831794 ! prostate gland development GO:0030850 5 5 0,000 0,03652898 0,11811037 ! metencephalon development GO:0022037 5 5 0,000 0,03652898 0,11790352 ! water transport GO:0006833 5 5 0,000 0,03652898 0,1176974 GO:0042044|fluid transport, ! forebrain regionalization GO:0021871 5 5 0,000 0,03652898 0,11749199 ! DNA synthesis during DNA repair GO:0000731 5 5 0,000 0,03652898 0,1172873 ! glycerol metabolic process GO:0006071 5 5 0,000 0,03652898 0,11708332 ! regulation of cellular amine metabolic process GO:0033238 5 5 0,000 0,03652898 0,11688005 GO:0042053|regulation of dopamine metabolic process, GO:0042069|regulation of catecholamine metabolic process, ! meiotic prophase I GO:0007128 5 5 0,000 0,03652898 0,11667749 GO:0051324|prophase, ! cell volume homeostasis GO:0006884 5 5 0,000 0,03652898 0,11647562 ! regulation of epidermal growth factor receptor activity GO:0007176 5 5 0,000 0,03652898 0,11627446 GO:0010469|regulation of receptor activity, ! regulation of long-term neuronal synaptic plasticity GO:0048169 5 5 0,000 0,03652898 0,11607398 ! filopodium assembly GO:0046847 7 5 0,000 0,03652898 0,1158742 GO:0030035|microspike assembly, ! CTP metabolic process GO:0046036 5 5 0,000 0,03652898 0,1156751 GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0006241|CTP biosynthetic process, ! Golgi to endosome transport GO:0006895 5 5 0,000 0,03652898 0,11547669 ! GTP metabolic process GO:0046039 5 5 0,000 0,03652898 0,11527896 ! establishment of tissue polarity GO:0007164 5 5 0,000 0,03652898 0,1150819 ! positive regulation of cell-cell adhesion GO:0022409 5 5 0,000 0,03652898 0,11488551 ! regulation of neurotransmitter secretion GO:0046928 5 5 0,000 0,03652898 0,1146898 GO:0001956|positive regulation of neurotransmitter secretion, ! neurotransmitter uptake GO:0001504 5 5 0,000 0,03652898 0,11449475 ! social behavior GO:0035176 5 5 0,000 0,03652898 0,11430036 ! macrophage chemotaxis GO:0048246 6 5 0,000 0,03652898 0,11410663 ! 2-oxoglutarate metabolic process GO:0006103 5 5 0,000 0,03652898 0,11391355 ! memory GO:0007613 5 5 0,000 0,03652898 0,11372113 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 5 5 0,000 0,03652898 0,11352936 ! membrane hyperpolarization GO:0060081 5 5 0,000 0,03652898 0,11333823 ! response to lipid GO:0033993 5 5 0,000 0,03652898 0,11314775 ! erythrocyte maturation GO:0043249 5 5 0,000 0,03652898 0,1129579 ! hippocampus development GO:0021766 6 5 0,000 0,03652898 0,11276869 ! regulation of carbohydrate biosynthetic process GO:0043255 5 5 0,000 0,03652898 0,11258012 ! glucocorticoid metabolic process GO:0008211 5 5 0,000 0,03652898 0,11239217 ! middle ear morphogenesis GO:0042474 5 5 0,000 0,03652898 0,11220485 ! amyloid precursor protein catabolic process GO:0042987 5 5 0,000 0,03652898 0,11201815 ! mechanosensory behavior GO:0007638 5 5 0,000 0,03652898 0,11183208 ! negative regulation of endocytosis GO:0045806 5 5 0,000 0,03652898 0,11164662 ! response to interferon-gamma GO:0034341 5 5 0,000 0,03652898 0,11146177 ! pseudouridine synthesis GO:0001522 5 5 0,000 0,03652898 0,11127754 ! endocrine pancreas development GO:0031018 5 5 0,000 0,03652898 0,11109391 ! pH reduction GO:0045851 5 5 0,000 0,03652898 0,11091089 GO:0051452|intracellular pH reduction, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 5 5 0,000 0,03652898 0,11072847 ! lipopolysaccharide metabolic process GO:0008653 5 5 0,000 0,03652898 0,11054665 ! positive regulation of chemokine biosynthetic process GO:0045080 5 5 0,000 0,03652898 0,11036543 ! sphingoid biosynthetic process GO:0046520 5 5 0,000 0,03652898 0,1101848 GO:0046513|ceramide biosynthetic process, ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 5 5 0,000 0,03652898 0,11000476 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! insulin-like growth factor receptor signaling pathway GO:0048009 5 5 0,000 0,03652898 0,1098253 ! photoreceptor cell maintenance GO:0045494 5 5 0,000 0,03652898 0,10964643 ! adrenal gland development GO:0030325 5 5 0,000 0,03652898 0,10946815 ! melanocyte differentiation GO:0030318 5 5 0,000 0,03652898 0,10929044 GO:0050931|pigment cell differentiation, ! ovulation GO:0030728 5 5 0,000 0,03652898 0,10911331 ! astrocyte differentiation GO:0048708 5 5 0,000 0,03652898 0,10893675 ! mitochondrial respiratory chain complex assembly GO:0033108 5 5 0,000 0,03652898 0,10876076 GO:0032981|mitochondrial respiratory chain complex I assembly, GO:0010257|NADH dehydrogenase complex assembly, ! pituitary gland development GO:0021983 5 5 0,000 0,03652898 0,10858534 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 5 5 0,000 0,03652898 0,10841048 GO:0033135|regulation of peptidyl-serine phosphorylation, ! tyrosine metabolic process GO:0006570 5 5 0,000 0,03652898 0,10823619 ! cytoskeletal anchoring at plasma membrane GO:0007016 6 5 0,000 0,03652898 0,10806246 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 5 5 0,000 0,03652898 0,10788928 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, GO:0009164|nucleoside catabolic process, ! microtubule nucleation GO:0007020 5 5 0,000 0,03652898 0,10771666 ! regulation of interleukin-6 biosynthetic process GO:0045408 5 5 0,000 0,03652898 0,10754458 ! regulation of interleukin-8 biosynthetic process GO:0045414 5 5 0,000 0,03652898 0,10737306 ! indolalkylamine metabolic process GO:0006586 5 5 0,000 0,03652898 0,10720209 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! muscle cell migration GO:0014812 5 5 0,000 0,03652898 0,10703165 ! phasic smooth muscle contraction GO:0014821 5 5 0,000 0,03652898 0,10686176 ! central nervous system neuron axonogenesis GO:0021955 6 5 0,000 0,03652898 0,10669241 GO:0021952|central nervous system projection neuron axonogenesis, ! sister chromatid cohesion GO:0007062 5 5 0,000 0,03652898 0,10652359 ! response to ATP GO:0033198 5 5 0,000 0,03652898 0,10635531 ! regulation of type I interferon production GO:0032479 5 5 0,000 0,03652898 0,10618756 ! regulation of appetite GO:0032098 5 5 0,000 0,03652898 0,10602033 GO:0032095|regulation of response to food, ! vesicle fusion GO:0006906 5 5 0,000 0,03652898 0,10585363 ! paraxial mesoderm development GO:0048339 5 5 0,000 0,03652898 0,10568746 ! regulation of the force of heart contraction GO:0002026 5 5 0,000 0,03652898 0,1055218 ! maintenance of protein location in nucleus GO:0051457 5 5 0,000 0,03652898 0,10535667 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,03652898 0,10519205 ! neurotransmitter biosynthetic process GO:0042136 6 5 0,000 0,03652898 0,10502794 ! fear response GO:0042596 5 5 0,000 0,03652898 0,10486435 ! lens development in camera-type eye GO:0002088 5 5 0,000 0,03652898 0,10470126 ! corticosteroid receptor signaling pathway GO:0031958 5 5 0,000 0,03652898 0,10453868 GO:0042921|glucocorticoid receptor signaling pathway, ! temperature homeostasis GO:0001659 5 5 0,000 0,03652898 0,1043766 ! positive regulation of exocytosis GO:0045921 6 5 0,000 0,03652898 0,10421503 ! parturition GO:0007567 5 5 0,000 0,03652898 0,10405396 ! Schwann cell differentiation GO:0014037 5 5 0,000 0,03652898 0,10389338 ! acyl-CoA metabolic process GO:0006637 5 5 0,000 0,03652898 0,1037333 ! wound healing, spreading of epidermal cells GO:0035313 5 5 0,000 0,03652898 0,10357371 ! regulation of gliogenesis GO:0014013 5 5 0,000 0,03652898 0,10341461 GO:0045685|regulation of glial cell differentiation, ! response to UV-B GO:0010224 5 5 0,000 0,03652898 0,103256 ! oligodendrocyte development GO:0014003 5 5 0,000 0,03652898 0,10309787 ! hyaluronan metabolic process GO:0030212 5 5 0,000 0,03652898 0,10294023 ! activated T cell proliferation GO:0050798 5 5 0,000 0,03652898 0,10278307 ! interaction with symbiont GO:0051702 5 5 0,000 0,03652898 0,10262639 ! cellular extravasation GO:0045123 5 5 0,000 0,03652898 0,10247018 ! positive regulation of axonogenesis GO:0050772 5 5 0,000 0,03652898 0,10231445 ! peptidyl-asparagine modification GO:0018196 5 5 0,000 0,03652898 0,1021592 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! positive regulation of phagocytosis GO:0050766 5 5 0,000 0,03652898 0,10200441 ! regulation of insulin receptor signaling pathway GO:0046626 5 5 0,000 0,03652898 0,10185009 ! antigen processing and presentation of exogenous antigen GO:0019884 5 5 0,000 0,03652898 0,10169624 ! enucleate erythrocyte differentiation GO:0043353 6 5 0,000 0,03652898 0,10154285 ! response to amine stimulus GO:0014075 5 5 0,000 0,03652898 0,10138992 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 6 5 0,000 0,03652898 0,10123746 ! glycosylceramide metabolic process GO:0006677 5 5 0,000 0,03652898 0,10108545 ! neuron recognition GO:0008038 5 5 0,000 0,03652898 0,1009339 ! decidualization GO:0046697 5 5 0,000 0,03652898 0,1007828 ! hair follicle maturation GO:0048820 5 5 0,000 0,03652898 0,10063215 ! phosphatidylinositol biosynthetic process GO:0006661 5 5 0,000 0,03652898 0,10048196 ! regulation of mitochondrial membrane potential GO:0051881 5 5 0,000 0,03652898 0,10033221 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 0,03652898 0,1001829 GO:0009155|purine deoxyribonucleotide catabolic process, ! regulation of interleukin-12 production GO:0032655 5 5 0,000 0,03652898 0,10003404 ! positive regulation of interleukin-6 production GO:0032755 5 5 0,000 0,03652898 0,09988562 ! postreplication repair GO:0006301 5 5 0,000 0,03652898 0,09973764 ! spinal cord motor neuron differentiation GO:0021522 5 5 0,000 0,03652898 0,0995901 GO:0021517|ventral spinal cord development, ! cellular pigmentation GO:0033059 5 5 0,000 0,03652898 0,099443 ! histone methylation GO:0016571 5 5 0,000 0,03652898 0,09929633 ! DNA methylation GO:0006306 5 5 0,000 0,03652898 0,09915009 GO:0006305|DNA alkylation, ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,03652898 0,09900428 ! positive regulation of interferon-gamma production GO:0032729 5 5 0,000 0,03652898 0,0988589 ! negative regulation of tumor necrosis factor production GO:0032720 5 5 0,000 0,03652898 0,09871394 ! intracellular cholesterol transport GO:0032367 5 5 0,000 0,03652898 0,09856941 GO:0032366|intracellular sterol transport, ! regulation of mast cell activation GO:0033003 5 5 0,000 0,03652898 0,09842531 ! morphogenesis of a polarized epithelium GO:0001738 5 5 0,000 0,03652898 0,09828162 ! regulation of transcription from RNA polymerase III promoter GO:0006359 5 5 0,000 0,03652898 0,09813835 ! regulation of inflammatory response to antigenic stimulus GO:0002861 5 5 0,000 0,03652898 0,0979955 ! sterol catabolic process GO:0016127 5 5 0,000 0,03652898 0,09785307 GO:0006707|cholesterol catabolic process, ! negative regulation of oxidoreductase activity GO:0051354 5 5 0,000 0,03652898 0,09771105 ! detection of biotic stimulus GO:0009595 5 5 0,000 0,03652898 0,09756944 ! regulation of immune response to tumor cell GO:0002837 5 5 0,000 0,03652898 0,09742823 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 5 5 0,000 0,03652898 0,09728744 ! zymogen activation GO:0031638 5 5 0,000 0,03652898 0,09714706 ! positive regulation of interleukin-1 beta secretion GO:0050718 5 5 0,000 0,03652898 0,09700708 ! cellular response to nutrient GO:0031670 5 5 0,000 0,03652898 0,0968675 ! peptidyl-histidine modification GO:0018202 5 5 0,000 0,03652898 0,09672832 ! nucleosome positioning GO:0016584 5 5 0,000 0,03652898 0,09658954 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 5 5 0,000 0,03652898 0,09645116 ! negative regulation of neurological system process GO:0031645 5 5 0,000 0,03652898 0,09631318 ! regulation of myoblast differentiation GO:0045661 5 5 0,000 0,03652898 0,09617559 ! NADPH regeneration GO:0006740 5 5 0,000 0,03652898 0,09603839 GO:0006098|pentose-phosphate shunt, ! positive regulation of epidermis development GO:0045684 5 5 0,000 0,03652898 0,09590158 ! positive regulation of leukocyte chemotaxis GO:0002690 5 5 0,000 0,03652898 0,09576516 GO:0002688|regulation of leukocyte chemotaxis, ! musculoskeletal movement GO:0050881 5 5 0,000 0,03652898 0,09562913 GO:0050879|multicellular organismal movement, ! neuromuscular process controlling posture GO:0050884 5 5 0,000 0,03652898 0,09549349 ! sarcomere organization GO:0045214 5 5 0,000 0,03652898 0,09535823 ! regulation of epidermal cell differentiation GO:0045604 5 5 0,000 0,03652898 0,09522335 ! activation of NF-kappaB-inducing kinase activity GO:0007250 5 5 0,000 0,03652898 0,09508886 ! negative regulation of glucose transport GO:0010829 5 5 0,000 0,03652898 0,09495474 GO:0046325|negative regulation of glucose import, ! positive regulation of T-helper cell differentiation GO:0045624 5 5 0,000 0,03652898 0,094821 GO:0045622|regulation of T-helper cell differentiation, ! oocyte differentiation GO:0009994 5 5 0,000 0,03652898 0,09468764 GO:0048599|oocyte development, ! dopamine biosynthetic process GO:0042416 5 5 0,000 0,03652898 0,09455465 ! regulation of protein homodimerization activity GO:0043496 6 5 0,000 0,03652898 0,09442203 ! spleen development GO:0048536 5 5 0,000 0,03652898 0,09428979 ! male genitalia development GO:0030539 5 5 0,000 0,03652898 0,09415792 ! nicotinamide nucleotide biosynthetic process GO:0019359 5 5 0,000 0,03652898 0,09402641 ! quaternary ammonium group transport GO:0015697 5 5 0,000 0,03652898 0,09389527 ! thyroid hormone metabolic process GO:0042403 5 5 0,000 0,03652898 0,0937645 ! leukocyte mediated cytotoxicity GO:0001909 5 5 0,000 0,03652898 0,09363409 ! positive regulation of viral reproduction GO:0048524 5 5 0,000 0,03652898 0,09350404 ! removal of superoxide radicals GO:0019430 6 5 0,000 0,03652898 0,09337436 ! myeloid cell homeostasis GO:0002262 5 5 0,000 0,03652898 0,09324503 ! regulation of fatty acid oxidation GO:0046320 5 5 0,000 0,03652898 0,09311606 ! regulation of Rac protein signal transduction GO:0035020 5 5 0,000 0,03652898 0,09298745 ! ATP catabolic process GO:0006200 5 5 0,000 0,03652898 0,09285919 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,03652898 0,09273128 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 5 5 0,000 0,03652898 0,09260373 ! blastocyst formation GO:0001825 5 5 0,000 0,03652898 0,09247652 ! regulation of fibrinolysis GO:0051917 5 5 0,000 0,03652898 0,09234967 ! embryonic gut development GO:0048566 5 5 0,000 0,03652898 0,09222316 ! negative regulation of organic acid transport GO:0032891 5 5 0,000 0,03652898 0,092097 ! pyrimidine base metabolic process GO:0006206 5 5 0,000 0,03652898 0,09197119 ! activation of innate immune response GO:0002218 5 5 0,000 0,03652898 0,09184572 GO:0002758|innate immune response-activating signal transduction, ! catecholamine transport GO:0051937 5 5 0,000 0,03652898 0,09172059 ! negative regulation of blood vessel endothelial cell migration GO:0043537 5 5 0,000 0,03652898 0,0915958 ! regulation of NF-kappaB import into nucleus GO:0042345 5 5 0,000 0,03652898 0,09147135 ! positive regulation of actin filament bundle formation GO:0032233 5 5 0,000 0,03652898 0,09134723 ! embryonic heart tube development GO:0035050 5 5 0,000 0,03652898 0,09122346 ! cardiac cell differentiation GO:0035051 6 5 0,000 0,03652898 0,09110001 ! positive regulation of homeostatic process GO:0032846 5 5 0,000 0,03652898 0,09097691 ! defense response to fungus GO:0050832 5 5 0,000 0,03652898 0,09085413 ! lysogeny GO:0030069 5 5 0,000 0,03652898 0,09073168 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 5 5 0,000 0,03652898 0,09060957 ! positive regulation of smooth muscle contraction GO:0045987 5 5 0,000 0,03652898 0,09048778 ! response to nicotine GO:0035094 5 5 0,000 0,03652898 0,09036632 ! establishment of cell polarity GO:0030010 5 5 0,000 0,03652898 0,09024519 ! mitochondrion localization GO:0051646 5 5 0,000 0,03652898 0,09012438 ! nucleus localization GO:0051647 5 5 0,000 0,03652898 0,09000389 ! regulation of synapse structure and activity GO:0050803 5 5 0,000 0,03652898 0,08988373 ! regulation of nucleotide biosynthetic process GO:0030808 41 41 1,000 0,03675954 0,09033044 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! cell cycle checkpoint GO:0000075 42 41 1,000 0,03675954 0,09021016 ! elevation of cytosolic calcium ion concentration GO:0007204 41 41 1,000 0,03675954 0,0900902 ! regulation of caspase activity GO:0043281 41 41 1,000 0,03675954 0,08997056 ! regulation of Ras GTPase activity GO:0032318 41 41 1,000 0,03675954 0,08985124 ! response to hormone stimulus GO:0009725 102 100 2,000 0,03753735 0,0916309 ! regulation of cyclic nucleotide metabolic process GO:0030799 42 42 1,000 0,0384178 0,0936561 ! regulation of endopeptidase activity GO:0052548 42 42 1,000 0,0384178 0,09353238 ! cytosolic calcium ion homeostasis GO:0051480 42 42 1,000 0,0384178 0,09340898 ! cell-substrate adhesion GO:0031589 43 42 1,000 0,0384178 0,09328592 ! development of primary sexual characteristics GO:0045137 42 42 1,000 0,0384178 0,09316317 ! protein ubiquitination GO:0016567 43 42 1,000 0,0384178 0,09304075 ! one-carbon metabolic process GO:0006730 42 42 1,000 0,0384178 0,09291865 ! reproductive structure development GO:0048608 43 43 1,000 0,04010434 0,09687063 ! mitochondrion organization GO:0007005 44 43 1,000 0,04010434 0,09674384 ! regulation of nucleotide metabolic process GO:0006140 43 43 1,000 0,04010434 0,09661738 ! protein import into nucleus GO:0006606 44 44 1,000 0,04181865 0,1006159 ! vitamin metabolic process GO:0006766 44 44 1,000 0,04181865 0,10048472 ! positive regulation of lymphocyte activation GO:0051251 44 44 1,000 0,04181865 0,10035388 ! amine biosynthetic process GO:0009309 46 45 1,000 0,04356026 0,10439735 ! homophilic cell adhesion GO:0007156 45 45 1,000 0,04356026 0,10426177 ! nuclear import GO:0051170 45 45 1,000 0,04356026 0,10412654 ! Wnt receptor signaling pathway GO:0016055 46 45 1,000 0,04356026 0,10399166 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 6 6 0,000 0,04367618 0,10413351 ! axon extension GO:0048675 7 6 0,000 0,04367618 0,10399897 ! oligosaccharide biosynthetic process GO:0009312 6 6 0,000 0,04367618 0,10386478 ! tRNA modification GO:0006400 6 6 0,000 0,04367618 0,10373094 ! somatic diversification of immune receptors via somatic mutation GO:0002566 6 6 0,000 0,04367618 0,10359743 GO:0016446|somatic hypermutation of immunoglobulin genes, ! 'de novo' posttranslational protein folding GO:0051084 6 6 0,000 0,04367618 0,10346427 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 6 6 0,000 0,04367618 0,10333146 ! negative regulation of cellular catabolic process GO:0031330 6 6 0,000 0,04367618 0,10319898 ! myotube differentiation GO:0014902 6 6 0,000 0,04367618 0,10306684 ! bone remodeling GO:0046849 6 6 0,000 0,04367618 0,10293505 ! N-glycan processing GO:0006491 6 6 0,000 0,04367618 0,10280358 ! regulation of lipid kinase activity GO:0043550 6 6 0,000 0,04367618 0,10267246 ! glycosaminoglycan catabolic process GO:0006027 6 6 0,000 0,04367618 0,10254166 ! negative regulation of JAK-STAT cascade GO:0046426 6 6 0,000 0,04367618 0,1024112 ! RNA methylation GO:0001510 6 6 0,000 0,04367618 0,10228107 ! regulation of activated T cell proliferation GO:0046006 6 6 0,000 0,04367618 0,10215128 ! succinate metabolic process GO:0006105 7 6 0,000 0,04367618 0,10202181 ! artery development GO:0060840 6 6 0,000 0,04367618 0,10189267 GO:0048844|artery morphogenesis, ! positive regulation of neurotransmitter transport GO:0051590 6 6 0,000 0,04367618 0,10176385 ! bile acid metabolic process GO:0008206 6 6 0,000 0,04367618 0,10163536 ! androgen metabolic process GO:0008209 6 6 0,000 0,04367618 0,1015072 ! estrogen metabolic process GO:0008210 6 6 0,000 0,04367618 0,10137935 ! limbic system development GO:0021761 7 6 0,000 0,04367618 0,10125183 ! cytoplasmic sequestering of transcription factor GO:0042994 6 6 0,000 0,04367618 0,10112463 ! positive regulation of heart contraction GO:0045823 6 6 0,000 0,04367618 0,10099775 ! positive regulation of gene expression, epigenetic GO:0045815 6 6 0,000 0,04367618 0,10087119 ! pathogenesis GO:0009405 6 6 0,000 0,04367618 0,10074494 ! positive regulation of cell growth GO:0030307 6 6 0,000 0,04367618 0,10061901 ! ribonucleoside triphosphate catabolic process GO:0009203 6 6 0,000 0,04367618 0,10049339 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! regulation of chemokine biosynthetic process GO:0045073 6 6 0,000 0,04367618 0,10036809 ! nerve growth factor receptor signaling pathway GO:0048011 6 6 0,000 0,04367618 0,1002431 ! inositol phosphate-mediated signaling GO:0048016 6 6 0,000 0,04367618 0,10011842 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 6 6 0,000 0,04367618 0,09999404 ! arginine metabolic process GO:0006525 6 6 0,000 0,04367618 0,09986998 GO:0006527|arginine catabolic process, ! regulation of catecholamine secretion GO:0050433 6 6 0,000 0,04367618 0,09974623 ! oligodendrocyte differentiation GO:0048709 6 6 0,000 0,04367618 0,09962278 ! glutamate catabolic process GO:0006538 7 6 0,000 0,04367618 0,09949964 ! telomere maintenance via telomerase GO:0007004 6 6 0,000 0,04367618 0,0993768 GO:0010833|telomere maintenance via telomere lengthening, ! L-phenylalanine metabolic process GO:0006558 6 6 0,000 0,04367618 0,09925426 GO:0006559|L-phenylalanine catabolic process, ! glucan biosynthetic process GO:0009250 6 6 0,000 0,04367618 0,09913203 GO:0005978|glycogen biosynthetic process, ! V(D)J recombination GO:0033151 6 6 0,000 0,04367618 0,09901009 ! focal adhesion formation GO:0048041 7 6 0,000 0,04367618 0,09888846 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 0,04367618 0,09876712 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 6 6 0,000 0,04367618 0,09864609 ! negative regulation of endothelial cell migration GO:0010596 6 6 0,000 0,04367618 0,09852534 ! regulation of heart rate GO:0002027 6 6 0,000 0,04367618 0,0984049 ! lipid digestion GO:0044241 6 6 0,000 0,04367618 0,09828474 ! asymmetric protein localization GO:0008105 6 6 0,000 0,04367618 0,09816489 ! retrograde transport, endosome to Golgi GO:0042147 6 6 0,000 0,04367618 0,09804532 ! phagocytosis, engulfment GO:0006911 6 6 0,000 0,04367618 0,09792604 ! Rac protein signal transduction GO:0016601 6 6 0,000 0,04367618 0,09780705 ! regulation of calcium ion transport into cytosol GO:0010522 6 6 0,000 0,04367618 0,09768836 ! ruffle organization GO:0031529 6 6 0,000 0,04367618 0,09756995 ! preassembly of GPI anchor in ER membrane GO:0016254 6 6 0,000 0,04367618 0,09745182 ! retinoic acid metabolic process GO:0042573 6 6 0,000 0,04367618 0,09733399 ! neutral amino acid transport GO:0015804 6 6 0,000 0,04367618 0,09721643 ! L-amino acid transport GO:0015807 6 6 0,000 0,04367618 0,09709916 ! bone mineralization GO:0030282 6 6 0,000 0,04367618 0,09698218 GO:0031214|biomineral formation, ! rRNA modification GO:0000154 6 6 0,000 0,04367618 0,09686547 ! negative regulation of ossification GO:0030279 6 6 0,000 0,04367618 0,09674905 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 6 6 0,000 0,04367618 0,0966329 GO:0002717|positive regulation of natural killer cell mediated immunity, GO:0002715|regulation of natural killer cell mediated immunity, GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 7 6 0,000 0,04367618 0,09651703 ! purine base biosynthetic process GO:0009113 6 6 0,000 0,04367618 0,09640144 ! negative regulation of axonogenesis GO:0050771 7 6 0,000 0,04367618 0,09628613 ! regulation of phagocytosis GO:0050764 6 6 0,000 0,04367618 0,09617109 ! regulation of organ growth GO:0046620 6 6 0,000 0,04367618 0,09605633 ! regulation of circadian rhythm GO:0042752 6 6 0,000 0,04367618 0,09594184 ! response to dsRNA GO:0043331 6 6 0,000 0,04367618 0,09582763 ! DNA unwinding during replication GO:0006268 6 6 0,000 0,04367618 0,09571368 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 6 6 0,000 0,04367618 0,09560001 GO:0009147|pyrimidine nucleoside triphosphate metabolic process, ! sphingomyelin metabolic process GO:0006684 6 6 0,000 0,04367618 0,0954866 ! positive regulation of B cell differentiation GO:0045579 6 6 0,000 0,04367618 0,09537347 ! multicellular organismal aging GO:0010259 6 6 0,000 0,04367618 0,0952606 ! respiratory chain complex IV assembly GO:0008535 6 6 0,000 0,04367618 0,095148 ! erythrocyte development GO:0048821 6 6 0,000 0,04367618 0,09503566 ! renal water homeostasis GO:0003091 6 6 0,000 0,04367618 0,09492359 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 6 6 0,000 0,04367618 0,09481179 GO:0043372|positive regulation of CD4-positive, alpha beta T cell differentiation, ! ribosomal large subunit biogenesis GO:0042273 6 6 0,000 0,04367618 0,09470024 ! regulation of Rho GTPase activity GO:0032319 6 6 0,000 0,04367618 0,09458896 ! ribosome assembly GO:0042255 6 6 0,000 0,04367618 0,09447794 ! positive regulation of Ras GTPase activity GO:0032320 6 6 0,000 0,04367618 0,09436718 ! diencephalon development GO:0021536 6 6 0,000 0,04367618 0,09425668 ! fucose catabolic process GO:0019317 6 6 0,000 0,04367618 0,09414644 GO:0042355|L-fucose catabolic process, ! nitric oxide metabolic process GO:0046209 6 6 0,000 0,04367618 0,09403646 GO:0006809|nitric oxide biosynthetic process, ! protein sumoylation GO:0016925 6 6 0,000 0,04367618 0,09392673 ! regulation of lipid transport GO:0032368 6 6 0,000 0,04367618 0,09381726 ! regulation of cell division GO:0051302 6 6 0,000 0,04367618 0,09370804 ! positive regulation of interleukin-1 secretion GO:0050716 6 6 0,000 0,04367618 0,09359908 ! cellular metabolic compound salvage GO:0043094 6 6 0,000 0,04367618 0,09349037 ! regulation of T-helper 2 type immune response GO:0002828 6 6 0,000 0,04367618 0,09338191 ! salivary gland morphogenesis GO:0007435 6 6 0,000 0,04367618 0,0932737 ! neuroblast proliferation GO:0007405 6 6 0,000 0,04367618 0,09316575 ! regulation of interleukin-1 beta secretion GO:0050706 6 6 0,000 0,04367618 0,09305804 ! regulation of glucose transport GO:0010827 6 6 0,000 0,04367618 0,09295058 GO:0046324|regulation of glucose import, ! intestinal absorption GO:0050892 6 6 0,000 0,04367618 0,09284337 ! methionine biosynthetic process GO:0009086 6 6 0,000 0,04367618 0,09273641 ! glutamine family amino acid biosynthetic process GO:0009084 6 6 0,000 0,04367618 0,0926297 ! thymus development GO:0048538 6 6 0,000 0,04367618 0,09252322 ! lymph node development GO:0048535 6 6 0,000 0,04367618 0,092417 ! organic cation transport GO:0015695 6 6 0,000 0,04367618 0,09231102 ! negative regulation of BMP signaling pathway GO:0030514 6 6 0,000 0,04367618 0,09220528 ! positive regulation of JNK cascade GO:0046330 7 6 0,000 0,04367618 0,09209978 ! sperm-egg recognition GO:0035036 7 6 0,000 0,04367618 0,09199452 GO:0007339|binding of sperm to zona pellucida, ! germ cell migration GO:0008354 6 6 0,000 0,04367618 0,0918895 ! establishment or maintenance of apical/basal cell polarity GO:0035088 6 6 0,000 0,04367618 0,09178473 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 6 6 0,000 0,04367618 0,09168019 ! alditol metabolic process GO:0019400 6 6 0,000 0,04367618 0,09157589 ! regulation of synaptic transmission, GABAergic GO:0032228 6 6 0,000 0,04367618 0,09147182 ! regulation of amino acid transport GO:0051955 6 6 0,000 0,04367618 0,091368 ! maternal placenta development GO:0001893 6 6 0,000 0,04367618 0,09126441 ! regulation of membrane potential GO:0042391 46 46 1,000 0,04532868 0,09461015 ! regulation of peptidase activity GO:0052547 46 46 1,000 0,04532868 0,09450313 ! regulation of blood pressure GO:0008217 48 47 1,000 0,04712344 0,09813391 ! sex differentiation GO:0007548 47 47 1,000 0,04712344 0,09802314 ! amine transport GO:0015837 47 47 1,000 0,04712344 0,09791263 ! calcium ion transport GO:0006816 48 48 1,000 0,04894407 0,10158099 ! regulation of cell cycle process GO:0010564 50 48 1,000 0,04894407 0,10146673 ! glycerophospholipid metabolic process GO:0006650 49 48 1,000 0,04894407 0,10135272 ! protein localization in nucleus GO:0034504 48 48 1,000 0,04894407 0,10123897 ! respiratory burst GO:0045730 7 7 0,000 0,0507714 0,104901 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 7 7 0,000 0,0507714 0,10478353 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 7 7 0,000 0,0507714 0,10466632 ! negative regulation of cell projection organization GO:0031345 8 7 0,000 0,0507714 0,10454937 ! positive regulation of blood pressure GO:0045777 7 7 0,000 0,0507714 0,10443269 ! pteridine and derivative biosynthetic process GO:0042559 7 7 0,000 0,0507714 0,10431626 ! double-strand break repair via homologous recombination GO:0000724 7 7 0,000 0,0507714 0,1042001 GO:0000725|recombinational repair, ! positive regulation of GTPase activity GO:0043547 7 7 0,000 0,0507714 0,10408419 ! SMAD protein nuclear translocation GO:0007184 7 7 0,000 0,0507714 0,10396854 ! cellular protein complex disassembly GO:0043624 8 7 0,000 0,0507714 0,10385315 GO:0043241|protein complex disassembly, ! hair follicle morphogenesis GO:0031069 7 7 0,000 0,0507714 0,10373801 ! gene silencing by RNA GO:0031047 7 7 0,000 0,0507714 0,10362313 ! regulation of receptor-mediated endocytosis GO:0048259 7 7 0,000 0,0507714 0,10350851 ! oxaloacetate metabolic process GO:0006107 7 7 0,000 0,0507714 0,10339413 ! regulation of neurotransmitter transport GO:0051588 7 7 0,000 0,0507714 0,10328001 ! keratinocyte proliferation GO:0043616 7 7 0,000 0,0507714 0,10316614 ! axis specification GO:0009798 7 7 0,000 0,0507714 0,10305252 ! negative regulation of muscle cell differentiation GO:0051148 7 7 0,000 0,0507714 0,10293915 ! visual behavior GO:0007632 7 7 0,000 0,0507714 0,10282603 GO:0008542|visual learning, ! startle response GO:0001964 7 7 0,000 0,0507714 0,10271316 ! amyloid precursor protein metabolic process GO:0042982 7 7 0,000 0,0507714 0,10260054 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 8 7 0,000 0,0507714 0,10248816 ! positive regulation of lipid metabolic process GO:0045834 7 7 0,000 0,0507714 0,10237603 ! negative regulation of lipid metabolic process GO:0045833 7 7 0,000 0,0507714 0,10226414 ! regulation of interferon-gamma biosynthetic process GO:0045072 7 7 0,000 0,0507714 0,1021525 ! endothelial cell differentiation GO:0045446 7 7 0,000 0,0507714 0,1020411 ! negative regulation of striated muscle development GO:0045843 7 7 0,000 0,0507714 0,10192994 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 7 7 0,000 0,0507714 0,10181903 ! digestive system development GO:0055123 7 7 0,000 0,0507714 0,10170836 GO:0048546|digestive tract morphogenesis, GO:0048547|gut morphogenesis, ! regulation of exit from mitosis GO:0007096 7 7 0,000 0,0507714 0,10159792 ! protein targeting to ER GO:0045047 8 7 0,000 0,0507714 0,10148773 ! cell differentiation in spinal cord GO:0021515 7 7 0,000 0,0507714 0,10137778 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 7 7 0,000 0,0507714 0,10126806 ! endoderm development GO:0007492 7 7 0,000 0,0507714 0,10115858 ! regulation of defense response to virus GO:0050688 7 7 0,000 0,0507714 0,10104934 ! glycolipid biosynthetic process GO:0009247 7 7 0,000 0,0507714 0,10094033 GO:0006688|glycosphingolipid biosynthetic process, ! response to hexose stimulus GO:0009746 7 7 0,000 0,0507714 0,10083156 GO:0034284|response to monosaccharide stimulus, GO:0009749|response to glucose stimulus, ! membrane protein ectodomain proteolysis GO:0006509 7 7 0,000 0,0507714 0,10072302 GO:0033619|membrane protein proteolysis, ! positive regulation of survival gene product expression GO:0045885 7 7 0,000 0,0507714 0,10061472 ! regulation of skeletal muscle fiber development GO:0048742 7 7 0,000 0,0507714 0,10050665 ! nucleotide-sugar metabolic process GO:0009225 7 7 0,000 0,0507714 0,10039881 ! complement activation, alternative pathway GO:0006957 7 7 0,000 0,0507714 0,1002912 ! arachidonic acid secretion GO:0050482 7 7 0,000 0,0507714 0,10018382 GO:0032309|icosanoid secretion, ! polyamine biosynthetic process GO:0006596 7 7 0,000 0,0507714 0,10007667 ! UV protection GO:0009650 7 7 0,000 0,0507714 0,09996975 ! DNA integration GO:0015074 7 7 0,000 0,0507714 0,09986306 ! myofibril assembly GO:0030239 7 7 0,000 0,0507714 0,0997566 GO:0055002|striated muscle cell development, ! positive regulation of muscle contraction GO:0045933 7 7 0,000 0,0507714 0,09965036 ! negative regulation of muscle contraction GO:0045932 7 7 0,000 0,0507714 0,09954435 ! chondroitin sulfate biosynthetic process GO:0030206 7 7 0,000 0,0507714 0,09943856 GO:0030204|chondroitin sulfate metabolic process, ! regulation of exocytosis GO:0017157 8 7 0,000 0,0507714 0,099333 ! phosphatidylcholine biosynthetic process GO:0006656 7 7 0,000 0,0507714 0,09922767 ! heparan sulfate proteoglycan metabolic process GO:0030201 7 7 0,000 0,0507714 0,09912255 GO:0015012|heparan sulfate proteoglycan biosynthetic process, ! stem cell development GO:0048864 7 7 0,000 0,0507714 0,09901766 GO:0019827|stem cell maintenance, ! alpha-beta T cell differentiation GO:0046632 7 7 0,000 0,0507714 0,09891299 ! negative regulation of myeloid leukocyte differentiation GO:0002762 7 7 0,000 0,0507714 0,09880854 ! NLS-bearing substrate import into nucleus GO:0006607 7 7 0,000 0,0507714 0,09870431 ! axon cargo transport GO:0008088 7 7 0,000 0,0507714 0,0986003 ! eating behavior GO:0042755 7 7 0,000 0,0507714 0,09849651 ! RNA-dependent DNA replication GO:0006278 7 7 0,000 0,0507714 0,09839294 ! purine nucleoside triphosphate catabolic process GO:0009146 7 7 0,000 0,0507714 0,09828959 ! regulation of interleukin-8 production GO:0032677 7 7 0,000 0,0507714 0,09818645 ! purine ribonucleotide catabolic process GO:0009154 7 7 0,000 0,0507714 0,09808353 ! ribosomal small subunit biogenesis GO:0042274 7 7 0,000 0,0507714 0,09798083 ! cranial nerve development GO:0021545 7 7 0,000 0,0507714 0,09787834 ! protein import into peroxisome matrix GO:0016558 7 7 0,000 0,0507714 0,09777606 ! induction of an organ GO:0001759 7 7 0,000 0,0507714 0,097674 ! leukocyte activation during immune response GO:0002366 7 7 0,000 0,0507714 0,09757215 GO:0002263|cell activation during immune response, ! response to estradiol stimulus GO:0032355 7 7 0,000 0,0507714 0,09747051 ! autonomic nervous system development GO:0048483 7 7 0,000 0,0507714 0,09736908 ! intracellular lipid transport GO:0032365 7 7 0,000 0,0507714 0,09726787 ! detection of chemical stimulus GO:0009593 8 7 0,000 0,0507714 0,09716686 ! platelet activation GO:0030168 8 7 0,000 0,0507714 0,09706607 ! negative regulation of cytokine secretion GO:0050710 7 7 0,000 0,0507714 0,09696548 ! regulation of interleukin-1 secretion GO:0050704 7 7 0,000 0,0507714 0,0968651 ! natural killer cell activation GO:0030101 7 7 0,000 0,0507714 0,09676493 ! NADP metabolic process GO:0006739 7 7 0,000 0,0507714 0,09666497 ! neuromuscular synaptic transmission GO:0007274 7 7 0,000 0,0507714 0,09656521 ! synaptic transmission, cholinergic GO:0007271 7 7 0,000 0,0507714 0,09646566 ! ubiquinone metabolic process GO:0006743 7 7 0,000 0,0507714 0,09636631 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, GO:0042375|quinone cofactor metabolic process, ! regulation of macrophage differentiation GO:0045649 8 7 0,000 0,0507714 0,09626717 ! positive regulation of acute inflammatory response GO:0002675 7 7 0,000 0,0507714 0,09616823 ! regulation of osteoclast differentiation GO:0045670 7 7 0,000 0,0507714 0,0960695 ! multicellular organismal water homeostasis GO:0050891 7 7 0,000 0,0507714 0,09597096 ! regulation of ATPase activity GO:0043462 7 7 0,000 0,0507714 0,09587263 ! cell-cell recognition GO:0009988 8 7 0,000 0,0507714 0,0957745 ! hormone catabolic process GO:0042447 7 7 0,000 0,0507714 0,09567657 ! dopamine metabolic process GO:0042417 7 7 0,000 0,0507714 0,09557884 ! cAMP biosynthetic process GO:0006171 7 7 0,000 0,0507714 0,09548132 ! oxygen transport GO:0015671 7 7 0,000 0,0507714 0,09538398 ! pyridine nucleotide biosynthetic process GO:0019363 7 7 0,000 0,0507714 0,09528685 ! biogenic amine catabolic process GO:0042402 7 7 0,000 0,0507714 0,09518992 ! regulation of axon extension GO:0030516 7 7 0,000 0,0507714 0,09509318 ! cell killing GO:0001906 7 7 0,000 0,0507714 0,09499664 ! adult feeding behavior GO:0008343 7 7 0,000 0,0507714 0,09490029 ! pyrimidine nucleotide catabolic process GO:0006244 7 7 0,000 0,0507714 0,09480414 ! positive regulation of protein polymerization GO:0032273 7 7 0,000 0,0507714 0,09470819 ! response to cold GO:0009409 7 7 0,000 0,0507714 0,09461243 ! gland development GO:0048732 51 49 1,000 0,0507901 0,09455166 ! divalent metal ion transport GO:0070838 49 49 1,000 0,0507901 0,09445625 ! response to nutrient GO:0007584 49 49 1,000 0,0507901 0,09436103 ! cofactor biosynthetic process GO:0051188 49 49 1,000 0,0507901 0,09426601 ! positive regulation of cell activation GO:0050867 49 49 1,000 0,0507901 0,09417117 GO:0002696|positive regulation of leukocyte activation, ! regulation of defense response GO:0031347 50 50 1,000 0,05266106 0,09754205 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 50 50 1,000 0,05266106 0,09744412 ! regulation of neurogenesis GO:0050767 51 50 1,000 0,05266106 0,09734638 ! protein modification by small protein conjugation GO:0032446 52 51 1,000 0,05455652 0,10074916 ! positive regulation of immune response GO:0050778 51 51 1,000 0,05455652 0,10064831 ! interphase of mitotic cell cycle GO:0051329 52 51 1,000 0,05455652 0,10054766 GO:0051325|interphase, ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 52 52 1,000 0,05647601 0,1039813 ! cell fate commitment GO:0045165 52 52 1,000 0,05647601 0,10387753 ! regulation of GTPase activity GO:0043087 53 52 1,000 0,05647601 0,10377396 ! regulation of body fluid levels GO:0050878 55 52 1,000 0,05647601 0,1036706 ! regulation of skeletal muscle tissue development GO:0048641 8 8 0,000 0,057815 0,10602293 ! negative regulation of muscle development GO:0048635 8 8 0,000 0,057815 0,10591754 ! very-long-chain fatty acid metabolic process GO:0000038 8 8 0,000 0,057815 0,10581236 ! positive regulation of translation GO:0045727 8 8 0,000 0,057815 0,10570738 ! superoxide anion generation GO:0042554 8 8 0,000 0,057815 0,10560262 ! sulfur amino acid biosynthetic process GO:0000097 8 8 0,000 0,057815 0,10549806 ! cGMP metabolic process GO:0046068 8 8 0,000 0,057815 0,10539371 GO:0006182|cGMP biosynthetic process, ! thyroid gland development GO:0030878 8 8 0,000 0,057815 0,10528957 ! 'de novo' protein folding GO:0006458 8 8 0,000 0,057815 0,10518563 ! dicarboxylic acid transport GO:0006835 8 8 0,000 0,057815 0,1050819 ! phosphoinositide phosphorylation GO:0046854 8 8 0,000 0,057815 0,10497837 ! embryonic hindlimb morphogenesis GO:0035116 8 8 0,000 0,057815 0,10487504 ! zinc ion transport GO:0006829 8 8 0,000 0,057815 0,10477192 ! embryonic forelimb morphogenesis GO:0035115 8 8 0,000 0,057815 0,104669 ! folic acid and derivative biosynthetic process GO:0009396 8 8 0,000 0,057815 0,10456628 ! regulation of neuronal synaptic plasticity GO:0048168 8 8 0,000 0,057815 0,10446377 ! cardiac muscle contraction GO:0060048 8 8 0,000 0,057815 0,10436145 ! lipid localization GO:0010876 8 8 0,000 0,057815 0,10425934 GO:0019915|lipid storage, ! response to pain GO:0048265 8 8 0,000 0,057815 0,10415742 ! response to cAMP GO:0051591 8 8 0,000 0,057815 0,10405571 ! COPI coating of Golgi vesicle GO:0048205 8 8 0,000 0,057815 0,10395419 GO:0048200|Golgi transport vesicle coating, ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 8 0,000 0,057815 0,10385287 ! negative regulation of transcription factor import into nucleus GO:0042992 8 8 0,000 0,057815 0,10375175 ! negative regulation of ion transport GO:0043271 8 8 0,000 0,057815 0,10365082 ! regulation of response to extracellular stimulus GO:0032104 8 8 0,000 0,057815 0,10355009 GO:0032107|regulation of response to nutrient levels, ! adult walking behavior GO:0007628 8 8 0,000 0,057815 0,10344956 ! sensory perception of taste GO:0050909 8 8 0,000 0,057815 0,10334922 ! organelle fusion GO:0048284 8 8 0,000 0,057815 0,10324907 ! pancreas development GO:0031016 8 8 0,000 0,057815 0,10314912 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 8 8 0,000 0,057815 0,10304936 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 8 8 0,000 0,057815 0,1029498 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 8 8 0,000 0,057815 0,10285043 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 8 8 0,000 0,057815 0,10275125 ! sperm motility GO:0030317 8 8 0,000 0,057815 0,10265226 ! regulation of striated muscle contraction GO:0006942 8 8 0,000 0,057815 0,10255346 ! DNA duplex unwinding GO:0032508 8 8 0,000 0,057815 0,10245485 GO:0032392|DNA geometric change, ! glycine metabolic process GO:0006544 8 8 0,000 0,057815 0,10235643 ! ribonucleotide catabolic process GO:0009261 8 8 0,000 0,057815 0,1022582 ! negative regulation of microtubule depolymerization GO:0007026 8 8 0,000 0,057815 0,10216016 GO:0031114|regulation of microtubule depolymerization, ! phosphagen metabolic process GO:0006599 8 8 0,000 0,057815 0,1020623 GO:0006600|creatine metabolic process, ! polyamine metabolic process GO:0006595 8 8 0,000 0,057815 0,10196463 ! Golgi organization GO:0007030 8 8 0,000 0,057815 0,10186715 ! cell-cell junction assembly GO:0007043 8 8 0,000 0,057815 0,10176986 ! regulation of stress fiber formation GO:0051492 9 8 0,000 0,057815 0,10167275 ! fructose metabolic process GO:0006000 8 8 0,000 0,057815 0,10157583 ! mannose metabolic process GO:0006013 9 8 0,000 0,057815 0,10147909 ! NAD metabolic process GO:0019674 8 8 0,000 0,057815 0,10138253 ! negative regulation of mitotic cell cycle GO:0045930 9 8 0,000 0,057815 0,10128616 ! plasma membrane fusion GO:0045026 8 8 0,000 0,057815 0,10118997 ! response to fungus GO:0009620 8 8 0,000 0,057815 0,10109397 ! stem cell differentiation GO:0048863 8 8 0,000 0,057815 0,10099814 ! alpha-beta T cell activation GO:0046631 8 8 0,000 0,057815 0,1009025 ! positive regulation of myeloid leukocyte differentiation GO:0002763 9 8 0,000 0,057815 0,10080704 ! embryonic digit morphogenesis GO:0042733 8 8 0,000 0,057815 0,10071176 ! regulation of cytokine production during immune response GO:0002718 8 8 0,000 0,057815 0,10061666 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 0,057815 0,10052174 ! regulation of vasodilation GO:0042312 8 8 0,000 0,057815 0,100427 ! vasoconstriction GO:0042310 8 8 0,000 0,057815 0,10033243 ! muscle cell development GO:0055001 8 8 0,000 0,057815 0,10023805 ! nucleoside triphosphate catabolic process GO:0009143 8 8 0,000 0,057815 0,10014384 ! regulation of fatty acid metabolic process GO:0019217 8 8 0,000 0,057815 0,10004981 ! sensory perception of pain GO:0019233 8 8 0,000 0,057815 0,09995595 ! gastrulation with mouth forming second GO:0001702 8 8 0,000 0,057815 0,09986227 ! immunoglobulin production during immune response GO:0002381 8 8 0,000 0,057815 0,09976877 GO:0002208|somatic diversification of immunoglobulins during immune response, GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! mRNA cleavage GO:0006379 8 8 0,000 0,057815 0,09967544 ! chromatin silencing GO:0006342 8 8 0,000 0,057815 0,09958228 ! tissue regeneration GO:0042246 8 8 0,000 0,057815 0,0994893 ! salivary gland development GO:0007431 8 8 0,000 0,057815 0,09939649 ! T cell homeostasis GO:0043029 8 8 0,000 0,057815 0,09930386 ! water homeostasis GO:0030104 8 8 0,000 0,057815 0,0992114 ! cofactor transport GO:0051181 8 8 0,000 0,057815 0,09911911 ! regulation of acute inflammatory response GO:0002673 8 8 0,000 0,057815 0,09902699 ! acid secretion GO:0046717 8 8 0,000 0,057815 0,09893504 ! C21-steroid hormone biosynthetic process GO:0006700 8 8 0,000 0,057815 0,09884327 ! protein-chromophore linkage GO:0018298 9 8 0,000 0,057815 0,09875166 ! branched chain family amino acid metabolic process GO:0009081 8 8 0,000 0,057815 0,09866022 ! catecholamine biosynthetic process GO:0042423 8 8 0,000 0,057815 0,09856896 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 8 8 0,000 0,057815 0,09847786 ! aromatic compound biosynthetic process GO:0019438 8 8 0,000 0,057815 0,09838693 ! regulation of organic acid transport GO:0032890 8 8 0,000 0,057815 0,09829616 ! positive regulation of calcium ion transport GO:0051928 8 8 0,000 0,057815 0,09820557 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 8 8 0,000 0,057815 0,09811514 ! regulation of multi-organism process GO:0043900 8 8 0,000 0,057815 0,09802488 ! positive regulation of amine transport GO:0051954 8 8 0,000 0,057815 0,09793478 ! developmental induction GO:0031128 8 8 0,000 0,057815 0,09784485 GO:0045168|cell-cell signaling involved in cell fate specification, ! peptide hormone secretion GO:0030072 8 8 0,000 0,057815 0,09775508 ! positive regulation of calcium-mediated signaling GO:0050850 8 8 0,000 0,057815 0,09766548 ! actin filament polymerization GO:0030041 9 8 0,000 0,057815 0,09757605 ! peptide hormone processing GO:0016486 8 8 0,000 0,057815 0,09748677 ! positive regulation of synaptic transmission GO:0050806 8 8 0,000 0,057815 0,09739766 ! regulation of steroid biosynthetic process GO:0050810 8 8 0,000 0,057815 0,09730871 ! sodium ion transport GO:0006814 53 53 1,000 0,05841909 0,09823575 ! carbohydrate biosynthetic process GO:0016051 53 53 1,000 0,05841909 0,0981462 ! response to virus GO:0009615 54 54 1,000 0,06038533 0,10135715 ! hormone metabolic process GO:0042445 55 54 1,000 0,06038533 0,10126493 ! sulfur metabolic process GO:0006790 55 54 1,000 0,06038533 0,10117287 ! protein modification by small protein conjugation or removal GO:0070647 56 55 1,000 0,06237428 0,10441035 ! extracellular structure organization GO:0043062 56 56 1,000 0,06438552 0,10767923 ! regulation of nervous system development GO:0051960 57 56 1,000 0,06438552 0,10758161 ! lactation GO:0007595 10 9 0,000 0,06480735 0,10818836 ! embryonic pattern specification GO:0009880 10 9 0,000 0,06480735 0,10809045 ! positive regulation of cell size GO:0045793 9 9 0,000 0,06480735 0,10799272 ! positive regulation of cell projection organization GO:0031346 9 9 0,000 0,06480735 0,10789516 ! regulation of membrane protein ectodomain proteolysis GO:0051043 9 9 0,000 0,06480735 0,10779778 ! positive regulation of protein complex assembly GO:0031334 9 9 0,000 0,06480735 0,10770058 ! cortical actin cytoskeleton organization GO:0030866 10 9 0,000 0,06480735 0,10760355 ! negative regulation of cell cycle process GO:0010948 9 9 0,000 0,06480735 0,1075067 ! viral genome replication GO:0019079 9 9 0,000 0,06480735 0,10741002 ! phospholipid catabolic process GO:0009395 9 9 0,000 0,06480735 0,10731352 ! copper ion transport GO:0006825 9 9 0,000 0,06480735 0,10721719 ! lipid phosphorylation GO:0046834 9 9 0,000 0,06480735 0,10712103 ! aminoglycan catabolic process GO:0006026 9 9 0,000 0,06480735 0,10702504 ! Golgi vesicle budding GO:0048194 9 9 0,000 0,06480735 0,10692923 ! regulation of cell-cell adhesion GO:0022407 9 9 0,000 0,06480735 0,10683358 ! RNA polyadenylation GO:0043631 9 9 0,000 0,06480735 0,10673811 GO:0006378|mRNA polyadenylation, ! gamma-aminobutyric acid signaling pathway GO:0007214 9 9 0,000 0,06480735 0,10664281 ! regulation of postsynaptic membrane potential GO:0060078 9 9 0,000 0,06480735 0,10654768 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 9 9 0,000 0,06480735 0,10645271 ! negative regulation of cytokine biosynthetic process GO:0042036 9 9 0,000 0,06480735 0,10635792 ! phospholipid efflux GO:0033700 9 9 0,000 0,06480735 0,1062633 ! response to alkaloid GO:0043279 10 9 0,000 0,06480735 0,10616884 ! cytokine biosynthetic process GO:0042089 9 9 0,000 0,06480735 0,10607455 GO:0042107|cytokine metabolic process, ! negative regulation of gene expression, epigenetic GO:0045814 9 9 0,000 0,06480735 0,10598043 ! regulation of interleukin-2 biosynthetic process GO:0045076 9 9 0,000 0,06480735 0,10588648 ! response to ethanol GO:0045471 9 9 0,000 0,06480735 0,10579269 ! pyrimidine ribonucleotide metabolic process GO:0009218 9 9 0,000 0,06480735 0,10569907 ! activation of pro-apoptotic gene products GO:0008633 9 9 0,000 0,06480735 0,10560561 ! methionine metabolic process GO:0006555 9 9 0,000 0,06480735 0,10551232 ! glutamine metabolic process GO:0006541 9 9 0,000 0,06480735 0,10541919 ! cerebral cortex development GO:0021987 9 9 0,000 0,06480735 0,10532623 ! response to osmotic stress GO:0006970 9 9 0,000 0,06480735 0,10523343 ! pigmentation during development GO:0048066 9 9 0,000 0,06480735 0,1051408 ! reverse cholesterol transport GO:0043691 9 9 0,000 0,06480735 0,10504832 ! central nervous system neuron development GO:0021954 10 9 0,000 0,06480735 0,10495601 ! pyrimidine ribonucleoside metabolic process GO:0046131 9 9 0,000 0,06480735 0,10486387 ! nucleobase biosynthetic process GO:0046112 9 9 0,000 0,06480735 0,10477188 ! substrate-bound cell migration GO:0006929 9 9 0,000 0,06480735 0,10468006 ! neurotransmitter metabolic process GO:0042133 11 9 0,000 0,06480735 0,10458839 ! negative regulation of caspase activity GO:0043154 9 9 0,000 0,06480735 0,10449689 ! branching involved in ureteric bud morphogenesis GO:0001658 9 9 0,000 0,06480735 0,10440555 GO:0060675|ureteric bud morphogenesis, ! L-glutamate transport GO:0015813 9 9 0,000 0,06480735 0,10431436 GO:0015800|acidic amino acid transport, ! peptide secretion GO:0002790 9 9 0,000 0,06480735 0,10422334 ! regulation of dephosphorylation GO:0035303 9 9 0,000 0,06480735 0,10413247 ! cotranslational protein targeting to membrane GO:0006613 10 9 0,000 0,06480735 0,10404176 ! positive regulation of alpha-beta T cell differentiation GO:0046638 9 9 0,000 0,06480735 0,10395121 ! ventricular cardiac muscle morphogenesis GO:0055010 9 9 0,000 0,06480735 0,10386082 ! behavioral interaction between organisms GO:0051705 9 9 0,000 0,06480735 0,10377059 ! negative regulation of protein import into nucleus GO:0042308 9 9 0,000 0,06480735 0,10368051 ! DNA replication initiation GO:0006270 9 9 0,000 0,06480735 0,10359059 ! prostaglandin metabolic process GO:0006693 9 9 0,000 0,06480735 0,10350082 GO:0006692|prostanoid metabolic process, ! DNA fragmentation involved in apoptosis GO:0006309 9 9 0,000 0,06480735 0,10341121 ! cellular amino acid derivative catabolic process GO:0042219 10 9 0,000 0,06480735 0,10332175 ! positive regulation of cytokine secretion GO:0050715 9 9 0,000 0,06480735 0,10323245 ! negative regulation of inflammatory response GO:0050728 9 9 0,000 0,06480735 0,1031433 ! negative regulation of protein secretion GO:0050709 9 9 0,000 0,06480735 0,10305431 ! positive regulation of transmission of nerve impulse GO:0051971 9 9 0,000 0,06480735 0,10296547 ! collagen catabolic process GO:0030574 9 9 0,000 0,06480735 0,10287678 ! aromatic amino acid family catabolic process GO:0009074 9 9 0,000 0,06480735 0,10278825 ! purine base metabolic process GO:0006144 9 9 0,000 0,06480735 0,10269987 ! gas transport GO:0015669 9 9 0,000 0,06480735 0,10261164 ! cholesterol efflux GO:0033344 9 9 0,000 0,06480735 0,10252356 ! estrogen receptor signaling pathway GO:0030520 9 9 0,000 0,06480735 0,10243563 ! somatic recombination of immunoglobulin gene segments GO:0016447 9 9 0,000 0,06480735 0,10234785 ! regulation of actin filament bundle formation GO:0032231 10 9 0,000 0,06480735 0,10226023 ! regulation of calcium-mediated signaling GO:0050848 9 9 0,000 0,06480735 0,10217275 ! actin filament-based movement GO:0030048 9 9 0,000 0,06480735 0,10208542 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 9 9 0,000 0,06480735 0,10199825 ! carboxylic acid transport GO:0046942 59 59 1,000 0,07054875 0,11093972 GO:0015849|organic acid transport, ! regulation of cell development GO:0060284 60 59 1,000 0,07054875 0,11084514 ! protein localization in organelle GO:0033365 59 59 1,000 0,07054875 0,11075072 ! immune effector process GO:0002252 59 59 1,000 0,07054875 0,11065647 ! protein import into nucleus, docking GO:0000059 10 10 0,000 0,07174882 0,11244309 ! regulation of protein ubiquitination GO:0031396 10 10 0,000 0,07174882 0,11234755 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 10 10 0,000 0,07174882 0,11225218 ! ER-associated protein catabolic process GO:0030433 10 10 0,000 0,07174882 0,11215697 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! neuron maturation GO:0042551 10 10 0,000 0,07174882 0,11206192 ! pteridine and derivative metabolic process GO:0042558 10 10 0,000 0,07174882 0,11196704 ! positive regulation of anti-apoptosis GO:0045768 10 10 0,000 0,07174882 0,11187231 GO:0045767|regulation of anti-apoptosis, ! cortical cytoskeleton organization GO:0030865 11 10 0,000 0,07174882 0,11177774 ! regulation of lipid biosynthetic process GO:0046890 10 10 0,000 0,07174882 0,11168334 ! reciprocal meiotic recombination GO:0007131 10 10 0,000 0,07174882 0,11158909 ! hormone secretion GO:0046879 10 10 0,000 0,07174882 0,111495 ! glucosamine metabolic process GO:0006041 10 10 0,000 0,07174882 0,11140107 GO:0006044|N-acetylglucosamine metabolic process, ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 10 10 0,000 0,07174882 0,1113073 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! cAMP metabolic process GO:0046058 10 10 0,000 0,07174882 0,11121368 ! vesicle targeting, to, from or within Golgi GO:0048199 10 10 0,000 0,07174882 0,11112023 ! transcription from RNA polymerase III promoter GO:0006383 10 10 0,000 0,07174882 0,11102693 ! forelimb morphogenesis GO:0035136 10 10 0,000 0,07174882 0,11093378 ! glial cell development GO:0021782 10 10 0,000 0,07174882 0,1108408 ! phototransduction GO:0007602 11 10 0,000 0,07174882 0,11074796 ! calcium-independent cell-cell adhesion GO:0016338 10 10 0,000 0,07174882 0,11065529 ! fat cell differentiation GO:0045444 10 10 0,000 0,07174882 0,11056277 ! myoblast differentiation GO:0045445 10 10 0,000 0,07174882 0,1104704 ! centrosome cycle GO:0007098 10 10 0,000 0,07174882 0,11037819 ! inactivation of MAPK activity GO:0000188 10 10 0,000 0,07174882 0,11028613 ! positive regulation of proteolysis GO:0045862 10 10 0,000 0,07174882 0,11019423 ! response to carbohydrate stimulus GO:0009743 10 10 0,000 0,07174882 0,11010247 ! regulation of survival gene product expression GO:0045884 10 10 0,000 0,07174882 0,11001087 ! induction of apoptosis via death domain receptors GO:0008625 10 10 0,000 0,07174882 0,10991943 ! epidermis morphogenesis GO:0048730 10 10 0,000 0,07174882 0,10982813 ! protein polyubiquitination GO:0000209 10 10 0,000 0,07174882 0,10973699 ! glutamate metabolic process GO:0006536 11 10 0,000 0,07174882 0,109646 ! plasma membrane organization GO:0007009 10 10 0,000 0,07174882 0,10955515 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 10 10 0,000 0,07174882 0,10946446 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cell-substrate junction assembly GO:0007044 11 10 0,000 0,07174882 0,10937392 ! lysosomal transport GO:0007041 10 10 0,000 0,07174882 0,10928353 ! cellular response to unfolded protein GO:0034620 10 10 0,000 0,07174882 0,10919329 GO:0030968|endoplasmic reticulum unfolded protein response, ! central nervous system neuron differentiation GO:0021953 11 10 0,000 0,07174882 0,10910319 ! purine ribonucleoside metabolic process GO:0046128 10 10 0,000 0,07174882 0,10901325 GO:0042278|purine nucleoside metabolic process, ! vesicle coating GO:0006901 10 10 0,000 0,07174882 0,10892345 ! exocrine system development GO:0035272 10 10 0,000 0,07174882 0,1088338 ! cell structure disassembly during apoptosis GO:0006921 10 10 0,000 0,07174882 0,1087443 ! embryo implantation GO:0007566 11 10 0,000 0,07174882 0,10865495 ! regulation of protein binding GO:0043393 11 10 0,000 0,07174882 0,10856574 ! protein targeting to peroxisome GO:0006625 10 10 0,000 0,07174882 0,10847668 ! protein targeting to mitochondrion GO:0006626 10 10 0,000 0,07174882 0,10838776 GO:0070585|protein localization in mitochondrion, ! regulation of alpha-beta T cell differentiation GO:0046637 10 10 0,000 0,07174882 0,10829899 ! intermediate filament cytoskeleton organization GO:0045104 10 10 0,000 0,07174882 0,10821037 ! protein export from nucleus GO:0006611 10 10 0,000 0,07174882 0,10812189 ! cytolysis GO:0019835 10 10 0,000 0,07174882 0,10803355 ! positive regulation of biomineral formation GO:0070169 10 10 0,000 0,07174882 0,10794536 GO:0030501|positive regulation of bone mineralization, ! mismatch repair GO:0006298 10 10 0,000 0,07174882 0,10785732 ! histone deacetylation GO:0016575 10 10 0,000 0,07174882 0,10776941 ! synaptic vesicle transport GO:0048489 11 10 0,000 0,07174882 0,10768165 ! gland morphogenesis GO:0022612 10 10 0,000 0,07174882 0,10759404 ! positive regulation of neurological system process GO:0031646 10 10 0,000 0,07174882 0,10750656 ! sphingolipid biosynthetic process GO:0030148 10 10 0,000 0,07174882 0,10741923 GO:0046467|membrane lipid biosynthetic process, ! sphingolipid catabolic process GO:0030149 10 10 0,000 0,07174882 0,10733204 GO:0046466|membrane lipid catabolic process, ! nerve-nerve synaptic transmission GO:0007270 10 10 0,000 0,07174882 0,10724499 ! regulation of epidermis development GO:0045682 10 10 0,000 0,07174882 0,10715808 ! folic acid and derivative metabolic process GO:0006760 10 10 0,000 0,07174882 0,10707131 ! negative regulation of neuron differentiation GO:0045665 10 10 0,000 0,07174882 0,10698468 ! aspartate family amino acid biosynthetic process GO:0009067 10 10 0,000 0,07174882 0,1068982 ! regulation of BMP signaling pathway GO:0030510 10 10 0,000 0,07174882 0,10681185 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 10 10 0,000 0,07174882 0,10672564 ! lymphocyte homeostasis GO:0002260 10 10 0,000 0,07174882 0,10663957 ! nerve development GO:0021675 10 10 0,000 0,07174882 0,10655364 ! gut development GO:0048565 10 10 0,000 0,07174882 0,10646785 ! mRNA 3'-end processing GO:0031124 10 10 0,000 0,07174882 0,1063822 ! negative regulation of cellular protein metabolic process GO:0032269 60 60 1,000 0,07264495 0,10762431 ! positive regulation of cellular protein metabolic process GO:0032270 61 61 1,000 0,07476136 0,11067083 ! lipid transport GO:0006869 62 62 1,000 0,07689758 0,11374176 ! protein import GO:0017038 62 62 1,000 0,07689758 0,11365055 ! di-, tri-valent inorganic cation transport GO:0015674 63 62 1,000 0,07689758 0,11355948 ! protein secretion GO:0009306 11 11 0,000 0,07863976 0,1160393 ! oligosaccharide metabolic process GO:0009311 11 11 0,000 0,07863976 0,11594647 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 11 11 0,000 0,07863976 0,11585379 ! myeloid leukocyte differentiation GO:0002573 12 11 0,000 0,07863976 0,11576125 ! negative regulation of defense response GO:0031348 11 11 0,000 0,07863976 0,11566886 ! G1 phase of mitotic cell cycle GO:0000080 12 11 0,000 0,07863976 0,11557662 ! determination of bilateral symmetry GO:0009855 11 11 0,000 0,07863976 0,11548453 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! phosphatidylinositol metabolic process GO:0046488 11 11 0,000 0,07863976 0,11539258 ! skin development GO:0043588 11 11 0,000 0,07863976 0,11530078 ! cellular component assembly involved in morphogenesis GO:0010927 11 11 0,000 0,07863976 0,11520913 ! microtubule-based transport GO:0010970 11 11 0,000 0,07863976 0,11511762 ! peroxisomal transport GO:0043574 11 11 0,000 0,07863976 0,11502626 ! heart contraction GO:0060047 11 11 0,000 0,07863976 0,11493504 GO:0003015|heart process, ! detection of light stimulus involved in sensory perception GO:0050962 12 11 0,000 0,07863976 0,11484397 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 11 11 0,000 0,07863976 0,11475304 ! negative regulation of endothelial cell proliferation GO:0001937 11 11 0,000 0,07863976 0,11466225 ! regulation of viral genome replication GO:0045069 11 11 0,000 0,07863976 0,11457161 ! spinal cord development GO:0021510 11 11 0,000 0,07863976 0,11448111 ! smooth muscle contraction GO:0006939 11 11 0,000 0,07863976 0,11439076 ! cellular macromolecular complex disassembly GO:0034623 12 11 0,000 0,07863976 0,11430054 ! mitotic spindle organization GO:0007052 11 11 0,000 0,07863976 0,11421047 ! fucose metabolic process GO:0006004 11 11 0,000 0,07863976 0,11412054 ! membrane budding GO:0006900 11 11 0,000 0,07863976 0,11403075 ! apoptotic nuclear changes GO:0030262 11 11 0,000 0,07863976 0,11394111 ! monoamine transport GO:0015844 11 11 0,000 0,07863976 0,1138516 ! regulation of cellular ketone metabolic process GO:0010565 11 11 0,000 0,07863976 0,11376223 ! response to lipopolysaccharide GO:0032496 11 11 0,000 0,07863976 0,11367301 ! body fluid secretion GO:0007589 11 11 0,000 0,07863976 0,11358392 ! intermediate filament-based process GO:0045103 11 11 0,000 0,07863976 0,11349498 ! cardiac muscle tissue morphogenesis GO:0055008 11 11 0,000 0,07863976 0,11340617 GO:0060415|muscle tissue morphogenesis, ! membrane depolarization GO:0051899 11 11 0,000 0,07863976 0,1133175 ! regulation of interleukin-2 production GO:0032663 11 11 0,000 0,07863976 0,11322897 ! oogenesis GO:0048477 11 11 0,000 0,07863976 0,11314058 ! negative regulation of angiogenesis GO:0016525 11 11 0,000 0,07863976 0,11305233 ! hindbrain development GO:0030902 11 11 0,000 0,07863976 0,11296421 ! steroid catabolic process GO:0006706 11 11 0,000 0,07863976 0,11287624 ! aromatic amino acid family metabolic process GO:0009072 11 11 0,000 0,07863976 0,11278839 ! proximal/distal pattern formation GO:0009954 11 11 0,000 0,07863976 0,11270069 ! somatic diversification of immunoglobulins GO:0016445 11 11 0,000 0,07863976 0,11261312 ! RNA 3'-end processing GO:0031123 11 11 0,000 0,07863976 0,11252569 ! negative regulation of cellular component organization GO:0051129 65 63 1,000 0,07905321 0,11302954 ! glucose metabolic process GO:0006006 63 63 1,000 0,07905321 0,11294192 ! glycerolipid metabolic process GO:0046486 65 64 1,000 0,08122787 0,11595892 ! anion transport GO:0006820 65 65 1,000 0,08342117 0,11899785 ! regulation of hormone levels GO:0010817 66 65 1,000 0,08342117 0,11890581 ! translational initiation GO:0006413 12 12 0,000 0,08548055 0,12174703 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 12 12 0,000 0,08548055 0,12165302 ! initiation of viral infection GO:0019059 12 12 0,000 0,08548055 0,12155915 ! DNA catabolic process, endonucleolytic GO:0000737 12 12 0,000 0,08548055 0,12146543 ! iron ion transport GO:0006826 13 12 0,000 0,08548055 0,12137185 ! phosphatidylcholine metabolic process GO:0046470 12 12 0,000 0,08548055 0,12127841 ! amino sugar metabolic process GO:0006040 12 12 0,000 0,08548055 0,12118512 ! protein amino acid ADP-ribosylation GO:0006471 12 12 0,000 0,08548055 0,12109197 ! heterophilic cell adhesion GO:0007157 12 12 0,000 0,08548055 0,12099897 ! hindlimb morphogenesis GO:0035137 12 12 0,000 0,08548055 0,12090611 ! xenobiotic metabolic process GO:0006805 12 12 0,000 0,08548055 0,12081339 ! glutamate signaling pathway GO:0007215 12 12 0,000 0,08548055 0,12072081 ! C21-steroid hormone metabolic process GO:0008207 13 12 0,000 0,08548055 0,12062838 ! regulation of muscle cell differentiation GO:0051147 13 12 0,000 0,08548055 0,12053608 ! cellular response to hydrogen peroxide GO:0070301 12 12 0,000 0,08548055 0,12044393 GO:0042744|hydrogen peroxide catabolic process, ! negative regulation of peptidase activity GO:0010466 12 12 0,000 0,08548055 0,12035192 ! actomyosin structure organization GO:0031032 12 12 0,000 0,08548055 0,12026004 ! microtubule organizing center organization GO:0031023 12 12 0,000 0,08548055 0,12016831 GO:0051297|centrosome organization, ! mitotic chromosome condensation GO:0007076 12 12 0,000 0,08548055 0,12007672 ! positive regulation of innate immune response GO:0045089 12 12 0,000 0,08548055 0,11998527 ! GPI anchor biosynthetic process GO:0006506 12 12 0,000 0,08548055 0,11989396 GO:0006505|GPI anchor metabolic process, ! glycoprotein catabolic process GO:0006516 13 12 0,000 0,08548055 0,11980278 ! acute-phase response GO:0006953 12 12 0,000 0,08548055 0,11971175 ! deoxyribonucleotide catabolic process GO:0009264 12 12 0,000 0,08548055 0,11962085 ! vacuolar transport GO:0007034 12 12 0,000 0,08548055 0,11953009 ! polysaccharide catabolic process GO:0000272 12 12 0,000 0,08548055 0,11943947 ! vesicle docking during exocytosis GO:0006904 12 12 0,000 0,08548055 0,11934898 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 12 12 0,000 0,08548055 0,11925864 ! barbed-end actin filament capping GO:0051016 12 12 0,000 0,08548055 0,11916843 GO:0051693|actin filament capping, ! osteoblast differentiation GO:0001649 12 12 0,000 0,08548055 0,11907835 ! male gonad development GO:0008584 12 12 0,000 0,08548055 0,11898841 ! regulation of tumor necrosis factor production GO:0032680 12 12 0,000 0,08548055 0,11889861 ! regulation of steroid metabolic process GO:0019218 12 12 0,000 0,08548055 0,11880894 ! regulation of interleukin-6 production GO:0032675 12 12 0,000 0,08548055 0,11871941 ! pallium development GO:0021543 13 12 0,000 0,08548055 0,11863001 ! cell fate determination GO:0001709 12 12 0,000 0,08548055 0,11854075 ! regulation of chromosome organization GO:0033044 12 12 0,000 0,08548055 0,11845162 ! positive regulation of multicellular organism growth GO:0040018 12 12 0,000 0,08548055 0,11836263 ! G1 phase GO:0051318 13 12 0,000 0,08548055 0,11827377 ! regulation of response to biotic stimulus GO:0002831 12 12 0,000 0,08548055 0,11818504 ! detection of light stimulus GO:0009583 13 12 0,000 0,08548055 0,11809645 ! synaptogenesis GO:0007416 12 12 0,000 0,08548055 0,11800798 ! hormone transport GO:0009914 12 12 0,000 0,08548055 0,11791965 ! neurotransmitter secretion GO:0007269 14 12 0,000 0,08548055 0,11783146 ! heme biosynthetic process GO:0006783 12 12 0,000 0,08548055 0,11774339 ! spermatid differentiation GO:0048515 13 12 0,000 0,08548055 0,11765546 GO:0007286|spermatid development, ! aromatic compound catabolic process GO:0019439 13 12 0,000 0,08548055 0,11756766 ! pyrimidine nucleotide biosynthetic process GO:0006221 12 12 0,000 0,08548055 0,11747998 ! neural tube closure GO:0001843 13 12 0,000 0,08548055 0,11739244 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! regulation of mitotic metaphase/anaphase transition GO:0030071 13 12 0,000 0,08548055 0,11730503 ! negative regulation of translation GO:0017148 12 12 0,000 0,08548055 0,11721775 ! regulation of microtubule polymerization or depolymerization GO:0031110 12 12 0,000 0,08548055 0,1171306 ! polysaccharide metabolic process GO:0005976 69 66 1,000 0,08563272 0,11725194 ! negative regulation of cell differentiation GO:0045596 68 67 1,000 0,08786215 0,12021525 ! Ras protein signal transduction GO:0007265 69 67 1,000 0,08786215 0,12012607 ! regulation of cell size GO:0008361 68 68 1,000 0,09010908 0,12310677 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 13 13 0,000 0,09227154 0,12596774 GO:0016444|somatic cell DNA recombination, ! negative regulation of actin filament polymerization GO:0030837 13 13 0,000 0,09227154 0,1258745 ! phenol metabolic process GO:0018958 13 13 0,000 0,09227154 0,12578139 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, GO:0009712|catechol metabolic process, ! G2/M transition of mitotic cell cycle GO:0000086 13 13 0,000 0,09227154 0,12568843 ! negative regulation of hormone secretion GO:0046888 13 13 0,000 0,09227154 0,1255956 ! 2'-deoxyribonucleotide metabolic process GO:0009394 13 13 0,000 0,09227154 0,12550291 GO:0019692|deoxyribose phosphate metabolic process, ! glycosaminoglycan biosynthetic process GO:0006024 13 13 0,000 0,09227154 0,12541036 ! positive regulation of JAK-STAT cascade GO:0046427 13 13 0,000 0,09227154 0,12531794 ! regeneration GO:0031099 13 13 0,000 0,09227154 0,12522566 ! keratinization GO:0031424 13 13 0,000 0,09227154 0,12513351 ! post-embryonic development GO:0009791 14 13 0,000 0,09227154 0,1250415 ! patterning of blood vessels GO:0001569 13 13 0,000 0,09227154 0,12494963 ! regulation of innate immune response GO:0045088 13 13 0,000 0,09227154 0,12485789 ! response to corticosteroid stimulus GO:0031960 13 13 0,000 0,09227154 0,12476628 GO:0051384|response to glucocorticoid stimulus, ! multicellular organismal catabolic process GO:0044243 13 13 0,000 0,09227154 0,12467481 ! autophagy GO:0006914 13 13 0,000 0,09227154 0,12458348 ! ureteric bud development GO:0001657 13 13 0,000 0,09227154 0,12449227 ! coenzyme catabolic process GO:0009109 13 13 0,000 0,09227154 0,1244012 GO:0046356|acetyl-CoA catabolic process, GO:0006099|tricarboxylic acid cycle, ! purine nucleoside monophosphate metabolic process GO:0009126 13 13 0,000 0,09227154 0,12431027 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of viral reproduction GO:0050792 13 13 0,000 0,09227154 0,12421946 ! nucleobase metabolic process GO:0009112 13 13 0,000 0,09227154 0,12412879 ! regulation of axonogenesis GO:0050770 14 13 0,000 0,09227154 0,12403825 ! positive regulation of neurogenesis GO:0050769 13 13 0,000 0,09227154 0,12394785 ! nucleotide-excision repair, DNA gap filling GO:0006297 13 13 0,000 0,09227154 0,12385757 ! vasodilation GO:0042311 14 13 0,000 0,09227154 0,12376743 ! glycosphingolipid metabolic process GO:0006687 13 13 0,000 0,09227154 0,12367742 GO:0006664|glycolipid metabolic process, ! neutrophil chemotaxis GO:0030593 14 13 0,000 0,09227154 0,12358753 ! long-chain fatty acid transport GO:0015909 13 13 0,000 0,09227154 0,12349778 ! negative regulation of Wnt receptor signaling pathway GO:0030178 13 13 0,000 0,09227154 0,12340816 ! cell-cell junction organization GO:0045216 13 13 0,000 0,09227154 0,12331867 ! negative regulation of myeloid cell differentiation GO:0045638 13 13 0,000 0,09227154 0,12322931 ! response to cytokine stimulus GO:0034097 13 13 0,000 0,09227154 0,12314008 ! activation of JUN kinase activity GO:0007257 13 13 0,000 0,09227154 0,12305097 ! alkene biosynthetic process GO:0043450 13 13 0,000 0,09227154 0,122962 GO:0019370|leukotriene biosynthetic process, ! purine nucleotide catabolic process GO:0006195 13 13 0,000 0,09227154 0,12287315 ! porphyrin biosynthetic process GO:0006779 13 13 0,000 0,09227154 0,12278444 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of cytokine production GO:0001818 13 13 0,000 0,09227154 0,12269585 ! pyrimidine nucleoside metabolic process GO:0006213 13 13 0,000 0,09227154 0,12260739 ! blastocyst development GO:0001824 13 13 0,000 0,09227154 0,12251905 ! telomere organization GO:0032200 13 13 0,000 0,09227154 0,12243085 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 13 13 0,000 0,09227154 0,12234277 ! regulation of amine transport GO:0051952 13 13 0,000 0,09227154 0,12225481 ! regulation of mitotic cell cycle GO:0007346 72 69 1,000 0,09237314 0,1223015 ! carboxylic acid biosynthetic process GO:0046394 70 70 1,000 0,09465397 0,12523134 GO:0016053|organic acid biosynthetic process, ! translational elongation GO:0006414 71 71 1,000 0,0969512 0,12817867 ! calcium ion homeostasis GO:0055074 71 71 1,000 0,0969512 0,12808679 GO:0006874|cellular calcium ion homeostasis, ! neuron fate commitment GO:0048663 14 14 0,000 0,09901308 0,13071712 ! sulfur amino acid metabolic process GO:0000096 14 14 0,000 0,09901308 0,13062355 ! regulation of interferon-gamma production GO:0032649 14 14 0,000 0,09901308 0,13053012 ! cellular aldehyde metabolic process GO:0006081 14 14 0,000 0,09901308 0,13043681 ! acetyl-CoA metabolic process GO:0006084 14 14 0,000 0,09901308 0,13034365 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 14 14 0,000 0,09901308 0,13025061 ! regulation of neuron projection development GO:0010975 15 14 0,000 0,09901308 0,13015771 ! protein amino acid deacetylation GO:0006476 14 14 0,000 0,09901308 0,13006493 ! aminoglycan biosynthetic process GO:0006023 14 14 0,000 0,09901308 0,1299723 ! vesicle docking GO:0048278 14 14 0,000 0,09901308 0,12987979 ! superoxide metabolic process GO:0006801 15 14 0,000 0,09901308 0,12978741 ! macromolecular complex disassembly GO:0032984 15 14 0,000 0,09901308 0,12969517 ! calcium-dependent cell-cell adhesion GO:0016339 14 14 0,000 0,09901308 0,12960306 ! isoprenoid biosynthetic process GO:0008299 14 14 0,000 0,09901308 0,12951107 ! hair cycle GO:0042633 14 14 0,000 0,09901308 0,12941922 GO:0022404|molting cycle process, GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042303|molting cycle, ! negative regulation of epithelial cell proliferation GO:0050680 14 14 0,000 0,09901308 0,1293275 ! multicellular organismal response to stress GO:0033555 14 14 0,000 0,09901308 0,12923591 ! lysosome organization GO:0007040 14 14 0,000 0,09901308 0,12914445 ! actin polymerization or depolymerization GO:0008154 15 14 0,000 0,09901308 0,12905311 ! D-ribose metabolic process GO:0006014 14 14 0,000 0,09901308 0,12896191 ! peptide transport GO:0015833 14 14 0,000 0,09901308 0,12887084 ! primary neural tube formation GO:0014020 15 14 0,000 0,09901308 0,12877989 ! peptide cross-linking GO:0018149 14 14 0,000 0,09901308 0,12868907 ! vitamin biosynthetic process GO:0009110 14 14 0,000 0,09901308 0,12859838 ! response to organic cyclic substance GO:0014070 15 14 0,000 0,09901308 0,12850782 ! leukotriene metabolic process GO:0006691 14 14 0,000 0,09901308 0,12841738 ! formation of primary germ layer GO:0001704 14 14 0,000 0,09901308 0,12832708 GO:0001707|mesoderm formation, ! DNA modification GO:0006304 14 14 0,000 0,09901308 0,1282369 ! collagen fibril organization GO:0030199 14 14 0,000 0,09901308 0,12814684 ! proteoglycan biosynthetic process GO:0030166 14 14 0,000 0,09901308 0,12805691 ! group transfer coenzyme metabolic process GO:0006752 14 14 0,000 0,09901308 0,12796711 ! positive regulation of osteoblast differentiation GO:0045669 14 14 0,000 0,09901308 0,12787744 ! neuromuscular process controlling balance GO:0050885 14 14 0,000 0,09901308 0,12778789 ! aspartate family amino acid metabolic process GO:0009066 14 14 0,000 0,09901308 0,12769846 ! response to molecule of bacterial origin GO:0002237 14 14 0,000 0,09901308 0,12760916 ! negative regulation of protein polymerization GO:0032272 14 14 0,000 0,09901308 0,12751999 ! muscle system process GO:0003012 72 72 1,000 0,09926449 0,1277545 ! coenzyme metabolic process GO:0006732 75 74 1,000 0,1039378 0,13367576 ! negative regulation of actin filament depolymerization GO:0030835 15 15 0,000 0,10570552 0,13585445 ! positive regulation of ossification GO:0045778 15 15 0,000 0,10570552 0,13575978 GO:0046852|positive regulation of bone remodeling, GO:0034105|positive regulation of tissue remodeling, ! negative regulation of protein complex assembly GO:0031333 15 15 0,000 0,10570552 0,13566524 ! protein amino acid O-linked glycosylation GO:0006493 15 15 0,000 0,10570552 0,13557083 ! cellular polysaccharide biosynthetic process GO:0033692 15 15 0,000 0,10570552 0,13547655 ! proteoglycan metabolic process GO:0006029 15 15 0,000 0,10570552 0,13538241 ! striated muscle cell differentiation GO:0051146 16 15 0,000 0,10570552 0,13528839 ! odontogenesis of dentine-containing tooth GO:0042475 15 15 0,000 0,10570552 0,1351945 ! detection of stimulus involved in sensory perception GO:0050906 16 15 0,000 0,10570552 0,13510075 ! ovarian follicle development GO:0001541 15 15 0,000 0,10570552 0,13500712 ! antigen processing and presentation of peptide antigen GO:0048002 15 15 0,000 0,10570552 0,13491363 ! regulation of smooth muscle contraction GO:0006940 15 15 0,000 0,10570552 0,13482026 ! deoxyribonucleotide metabolic process GO:0009262 15 15 0,000 0,10570552 0,13472703 ! complement activation, classical pathway GO:0006958 15 15 0,000 0,10570552 0,13463392 ! heme metabolic process GO:0042168 15 15 0,000 0,10570552 0,13454094 ! mesoderm morphogenesis GO:0048332 15 15 0,000 0,10570552 0,13444809 ! chromosome condensation GO:0030261 15 15 0,000 0,10570552 0,13435537 ! response to mechanical stimulus GO:0009612 15 15 0,000 0,10570552 0,13426277 ! hydrogen peroxide metabolic process GO:0042743 15 15 0,000 0,10570552 0,1341703 ! regulation of biomineral formation GO:0070167 15 15 0,000 0,10570552 0,13407796 GO:0030500|regulation of bone mineralization, ! cyclic nucleotide biosynthetic process GO:0009190 15 15 0,000 0,10570552 0,13398575 ! cholesterol biosynthetic process GO:0006695 15 15 0,000 0,10570552 0,13389366 ! phospholipid transport GO:0015914 15 15 0,000 0,10570552 0,1338017 ! leukocyte homeostasis GO:0001776 15 15 0,000 0,10570552 0,13370987 ! regulation of cytokine secretion GO:0050707 15 15 0,000 0,10570552 0,13361816 ! nicotinamide metabolic process GO:0006769 15 15 0,000 0,10570552 0,13352658 GO:0046496|nicotinamide nucleotide metabolic process, ! cellular alkene metabolic process GO:0043449 15 15 0,000 0,10570552 0,13343512 ! somatic diversification of immune receptors GO:0002200 15 15 0,000 0,10570552 0,13334379 ! protein homooligomerization GO:0051260 15 15 0,000 0,10570552 0,13325259 ! response to oxidative stress GO:0006979 76 75 1,000 0,10629713 0,13390678 ! cellular metal ion homeostasis GO:0006875 77 77 1,000 0,11105946 0,13981051 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 16 16 0,000 0,11234923 0,14133763 ! alkaloid metabolic process GO:0009820 16 16 0,000 0,11234923 0,14124122 ! regulation of synaptic plasticity GO:0048167 16 16 0,000 0,11234923 0,14114494 ! learning GO:0007612 16 16 0,000 0,11234923 0,14104879 ! circadian rhythm GO:0007623 16 16 0,000 0,11234923 0,14095277 ! inner ear morphogenesis GO:0042472 16 16 0,000 0,11234923 0,14085689 ! positive regulation of mitosis GO:0045840 16 16 0,000 0,11234923 0,14076113 GO:0051785|positive regulation of nuclear division, ! vacuole organization GO:0007033 16 16 0,000 0,11234923 0,14066551 ! cellular response to reactive oxygen species GO:0034614 16 16 0,000 0,11234923 0,14057001 ! positive regulation of cytoskeleton organization GO:0051495 16 16 0,000 0,11234923 0,14047464 ! vesicle targeting GO:0006903 17 16 0,000 0,11234923 0,14037941 ! fatty acid beta-oxidation GO:0006635 16 16 0,000 0,11234923 0,1402843 ! triglyceride metabolic process GO:0006641 16 16 0,000 0,11234923 0,14018932 ! positive regulation of cell development GO:0010720 16 16 0,000 0,11234923 0,14009447 ! regulation of myeloid leukocyte differentiation GO:0002761 17 16 0,000 0,11234923 0,13999975 ! cell fate specification GO:0001708 16 16 0,000 0,11234923 0,13990515 ! pentose metabolic process GO:0019321 16 16 0,000 0,11234923 0,13981069 ! fatty acid transport GO:0015908 16 16 0,000 0,11234923 0,13971635 ! regulation of microtubule cytoskeleton organization GO:0070507 16 16 0,000 0,11234923 0,13962213 ! cofactor catabolic process GO:0051187 16 16 0,000 0,11234923 0,13952805 ! ethanolamine and derivative metabolic process GO:0042439 17 16 0,000 0,11234923 0,13943409 ! glutamine family amino acid catabolic process GO:0009065 17 16 0,000 0,11234923 0,13934026 ! porphyrin metabolic process GO:0006778 16 16 0,000 0,11234923 0,13924655 GO:0033013|tetrapyrrole metabolic process, ! embryonic epithelial tube formation GO:0001838 17 16 0,000 0,11234923 0,13915297 GO:0001841|neural tube formation, ! regulation of JUN kinase activity GO:0043506 17 16 0,000 0,11234923 0,13905952 GO:0043507|positive regulation of JUN kinase activity, ! regulation of cell morphogenesis involved in differentiation GO:0010769 17 16 0,000 0,11234923 0,13896619 ! metal ion homeostasis GO:0055065 78 78 1,000 0,11346179 0,14024821 ! nuclear transport GO:0051169 79 79 1,000 0,11587778 0,14313858 GO:0006913|nucleocytoplasmic transport, ! regulation of actin filament depolymerization GO:0030834 17 17 0,000 0,11894453 0,14682838 ! phosphoinositide biosynthetic process GO:0046489 17 17 0,000 0,11894453 0,1467301 ! nucleotide-excision repair, DNA damage removal GO:0000718 18 17 0,000 0,11894453 0,14663196 ! dicarboxylic acid metabolic process GO:0043648 18 17 0,000 0,11894453 0,14653394 ! sensory perception of smell GO:0007608 17 17 0,000 0,11894453 0,14643606 ! glucose transport GO:0015758 17 17 0,000 0,11894453 0,1463383 ! cell junction assembly GO:0034329 18 17 0,000 0,11894453 0,14624068 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 17 17 0,000 0,11894453 0,14614318 ! embryonic skeletal system morphogenesis GO:0048704 17 17 0,000 0,11894453 0,14604582 ! cellular carbohydrate biosynthetic process GO:0034637 17 17 0,000 0,11894453 0,14594859 ! development of primary male sexual characteristics GO:0046546 17 17 0,000 0,11894453 0,14585148 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 17 17 0,000 0,11894453 0,14575451 ! response to toxin GO:0009636 18 17 0,000 0,11894453 0,14565766 ! cell recognition GO:0008037 18 17 0,000 0,11894453 0,14556094 ! regulation of osteoblast differentiation GO:0045667 17 17 0,000 0,11894453 0,14546435 ! pyridine nucleotide metabolic process GO:0019362 17 17 0,000 0,11894453 0,14536789 ! pigmentation GO:0043473 17 17 0,000 0,11894453 0,14527155 ! myeloid leukocyte activation GO:0002274 18 17 0,000 0,11894453 0,14517535 ! adult locomotory behavior GO:0008344 17 17 0,000 0,11894453 0,14507927 ! regulation of calcium ion transport GO:0051924 17 17 0,000 0,11894453 0,14498332 ! liver development GO:0001889 17 17 0,000 0,11894453 0,14488749 ! gene silencing GO:0016458 17 17 0,000 0,11894453 0,14479179 ! mRNA export from nucleus GO:0006406 18 18 0,000 0,12549179 0,15266097 ! regulation of cell projection organization GO:0031344 19 18 0,000 0,12549179 0,15256027 ! icosanoid biosynthetic process GO:0046456 18 18 0,000 0,12549179 0,1524597 ! meiosis I GO:0007127 18 18 0,000 0,12549179 0,15235927 ! regulation of metal ion transport GO:0010959 18 18 0,000 0,12549179 0,15225897 ! membrane docking GO:0022406 18 18 0,000 0,12549179 0,1521588 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 18 18 0,000 0,12549179 0,15205876 ! response to calcium ion GO:0051592 18 18 0,000 0,12549179 0,15195885 ! negative regulation of response to external stimulus GO:0032102 18 18 0,000 0,12549179 0,15185908 ! hexose transport GO:0008645 18 18 0,000 0,12549179 0,15175943 GO:0015749|monosaccharide transport, ! cholesterol homeostasis GO:0042632 18 18 0,000 0,12549179 0,15165992 GO:0055092|sterol homeostasis, ! striated muscle contraction GO:0006941 18 18 0,000 0,12549179 0,15156053 ! neutral lipid metabolic process GO:0006638 18 18 0,000 0,12549179 0,15146128 GO:0006639|acylglycerol metabolic process, ! ceramide metabolic process GO:0006672 18 18 0,000 0,12549179 0,15136215 GO:0046519|sphingoid metabolic process, ! ribonucleoside monophosphate metabolic process GO:0009161 18 18 0,000 0,12549179 0,15126316 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! telencephalon development GO:0021537 19 18 0,000 0,12549179 0,1511643 ! negative regulation of MAP kinase activity GO:0043407 18 18 0,000 0,12549179 0,15106556 ! BMP signaling pathway GO:0030509 18 18 0,000 0,12549179 0,15096695 ! regulation of microtubule-based process GO:0032886 18 18 0,000 0,12549179 0,15086847 ! establishment of vesicle localization GO:0051650 19 18 0,000 0,12549179 0,15077013 ! cellular amino acid derivative metabolic process GO:0006575 87 84 1,000 0,12815157 0,15386537 ! nitrogen compound biosynthetic process GO:0044271 86 85 1,000 0,1306429 0,15675447 ! activation of adenylate cyclase activity GO:0007190 19 19 0,000 0,13199134 0,15826938 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 19 19 0,000 0,13199134 0,15816648 GO:0006956|complement activation, ! glial cell differentiation GO:0010001 19 19 0,000 0,13199134 0,15806371 ! regulation of JAK-STAT cascade GO:0046425 19 19 0,000 0,13199134 0,15796107 ! feeding behavior GO:0007631 19 19 0,000 0,13199134 0,15785856 ! peroxisome organization GO:0007031 19 19 0,000 0,13199134 0,15775619 ! regulation of striated muscle tissue development GO:0016202 20 19 0,000 0,13199134 0,15765395 ! metanephros development GO:0001656 19 19 0,000 0,13199134 0,15755184 ! ribonucleoside metabolic process GO:0009119 19 19 0,000 0,13199134 0,15744987 ! nuclear-transcribed mRNA catabolic process GO:0000956 19 19 0,000 0,13199134 0,15734802 ! hormone biosynthetic process GO:0042446 19 19 0,000 0,13199134 0,15724631 ! biogenic amine biosynthetic process GO:0042401 20 19 0,000 0,13199134 0,15714473 ! dorsal/ventral pattern formation GO:0009953 19 19 0,000 0,13199134 0,15704328 ! response to heat GO:0009408 19 19 0,000 0,13199134 0,15694196 ! vesicle localization GO:0051648 20 19 0,000 0,13199134 0,15684078 ! organophosphate metabolic process GO:0019637 87 86 1,000 0,13314571 0,15811054 GO:0006644|phospholipid metabolic process, ! hexose metabolic process GO:0019318 87 86 1,000 0,13314571 0,15800873 ! male gamete generation GO:0048232 90 88 1,000 0,13818459 0,16388301 GO:0007283|spermatogenesis, ! regulation of muscle development GO:0048634 21 20 0,000 0,13844353 0,16408452 ! establishment or maintenance of cell polarity GO:0007163 21 20 0,000 0,13844353 0,16397906 ! organic ether metabolic process GO:0018904 20 20 0,000 0,13844353 0,16387375 GO:0006662|glycerol ether metabolic process, ! cytoskeleton-dependent intracellular transport GO:0030705 20 20 0,000 0,13844353 0,16376856 ! neural tube development GO:0021915 21 20 0,000 0,13844353 0,16366352 ! nucleus organization GO:0006997 20 20 0,000 0,13844353 0,1635586 ! phagocytosis GO:0006909 21 20 0,000 0,13844353 0,16345383 ! unsaturated fatty acid biosynthetic process GO:0006636 20 20 0,000 0,13844353 0,16334918 ! protein targeting to membrane GO:0006612 22 20 0,000 0,13844353 0,16324467 ! cyclic nucleotide metabolic process GO:0009187 20 20 0,000 0,13844353 0,16314029 ! chromatin remodeling GO:0006338 20 20 0,000 0,13844353 0,16303605 ! detection of abiotic stimulus GO:0009582 21 20 0,000 0,13844353 0,16293194 ! lipid oxidation GO:0034440 20 20 0,000 0,13844353 0,16282797 GO:0019395|fatty acid oxidation, ! female gamete generation GO:0007292 20 20 0,000 0,13844353 0,16272412 ! negative regulation of neuron apoptosis GO:0043524 21 20 0,000 0,13844353 0,16262041 ! RNA modification GO:0009451 20 20 0,000 0,13844353 0,16251683 ! single fertilization GO:0007338 21 20 0,000 0,13844353 0,16241338 ! chemotaxis GO:0006935 90 89 1,000 0,14072006 0,16497906 GO:0042330|taxis, ! regulation of Ras protein signal transduction GO:0046578 90 90 1,000 0,14326585 0,16785694 ! mitotic sister chromatid segregation GO:0000070 21 21 0,000 0,14484868 0,16960364 ! mRNA catabolic process GO:0006402 21 21 0,000 0,14484868 0,16949595 ! positive regulation of adenylate cyclase activity GO:0045762 21 21 0,000 0,14484868 0,16938841 GO:0051349|positive regulation of lyase activity, GO:0031281|positive regulation of cyclase activity, ! protein amino acid lipidation GO:0006497 21 21 0,000 0,14484868 0,16928099 ! receptor-mediated endocytosis GO:0006898 21 21 0,000 0,14484868 0,16917372 ! Notch signaling pathway GO:0007219 22 21 0,000 0,14484868 0,16906658 ! morphogenesis of embryonic epithelium GO:0016331 22 21 0,000 0,14484868 0,16895957 ! ear morphogenesis GO:0042471 21 21 0,000 0,14484868 0,1688527 ! organic anion transport GO:0015711 21 21 0,000 0,14484868 0,16874597 ! cholesterol transport GO:0030301 21 21 0,000 0,14484868 0,16863937 GO:0015918|sterol transport, ! regulation of Rab protein signal transduction GO:0032483 21 21 0,000 0,14484868 0,16853291 GO:0032313|regulation of Rab GTPase activity, ! regulation of multicellular organism growth GO:0040014 21 21 0,000 0,14484868 0,16842658 ! regulation of proteolysis GO:0030162 21 21 0,000 0,14484868 0,16832038 ! DNA replication GO:0006260 91 91 1,000 0,14582166 0,16934425 ! visual perception GO:0007601 93 92 1,000 0,14838722 0,17221515 GO:0050953|sensory perception of light stimulus, ! energy derivation by oxidation of organic compounds GO:0015980 94 92 1,000 0,14838722 0,17210677 ! RNA export from nucleus GO:0006405 22 22 0,000 0,15120715 0,17526716 ! sister chromatid segregation GO:0000819 22 22 0,000 0,15120715 0,17515699 ! cellular amide metabolic process GO:0043603 22 22 0,000 0,15120715 0,17504697 ! regulation of ion transport GO:0043269 22 22 0,000 0,15120715 0,17493709 ! odontogenesis GO:0042476 22 22 0,000 0,15120715 0,17482734 ! cell junction organization GO:0034330 23 22 0,000 0,15120715 0,17471773 ! hormone-mediated signaling GO:0009755 22 22 0,000 0,15120715 0,17460826 ! ovulation cycle process GO:0022602 22 22 0,000 0,15120715 0,17449892 ! spindle organization GO:0007051 22 22 0,000 0,15120715 0,17438972 ! pigment biosynthetic process GO:0046148 22 22 0,000 0,15120715 0,17428066 ! cell chemotaxis GO:0060326 23 22 0,000 0,15120715 0,17417174 GO:0030595|leukocyte chemotaxis, ! respiratory gaseous exchange GO:0007585 22 22 0,000 0,15120715 0,17406295 ! erythrocyte differentiation GO:0030218 23 22 0,000 0,15120715 0,17395429 ! male sex differentiation GO:0046661 22 22 0,000 0,15120715 0,17384578 ! sterol biosynthetic process GO:0016126 22 22 0,000 0,15120715 0,17373739 ! detection of external stimulus GO:0009581 23 22 0,000 0,15120715 0,17362915 ! neuron migration GO:0001764 22 22 0,000 0,15120715 0,17352103 ! regulation of Wnt receptor signaling pathway GO:0030111 23 22 0,000 0,15120715 0,17341305 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 22 22 0,000 0,15120715 0,17330521 ! fatty acid catabolic process GO:0009062 23 22 0,000 0,15120715 0,1731975 ! aerobic respiration GO:0009060 22 22 0,000 0,15120715 0,17308992 ! cytokine production GO:0001816 22 22 0,000 0,15120715 0,17298248 ! cytokinesis GO:0000910 23 22 0,000 0,15120715 0,17287517 ! pyrimidine nucleotide metabolic process GO:0006220 22 22 0,000 0,15120715 0,172768 ! epidermis development GO:0008544 94 94 1,000 0,15354648 0,17533219 ! cofactor metabolic process GO:0051186 95 94 1,000 0,15354648 0,17522363 ! response to hydrogen peroxide GO:0042542 24 23 0,000 0,15751926 0,17964604 ! epithelial cell differentiation GO:0030855 23 23 0,000 0,15751926 0,17953494 ! viral infectious cycle GO:0019058 23 23 0,000 0,15751926 0,17942398 ! response to estrogen stimulus GO:0043627 23 23 0,000 0,15751926 0,17931315 ! negative regulation of protein complex disassembly GO:0043242 23 23 0,000 0,15751926 0,17920247 ! induction of apoptosis by extracellular signals GO:0008624 23 23 0,000 0,15751926 0,17909191 ! endocrine system development GO:0035270 23 23 0,000 0,15751926 0,1789815 ! lipoprotein biosynthetic process GO:0042158 23 23 0,000 0,15751926 0,17887122 ! female gonad development GO:0008585 23 23 0,000 0,15751926 0,17876108 ! lipid homeostasis GO:0055088 23 23 0,000 0,15751926 0,17865107 ! Rho protein signal transduction GO:0007266 24 23 0,000 0,15751926 0,1785412 ! regulation of JNK cascade GO:0046328 25 23 0,000 0,15751926 0,17843147 ! gliogenesis GO:0042063 24 24 0,000 0,16378534 0,18541547 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 26 24 0,000 0,16378534 0,18530165 ! heterocycle biosynthetic process GO:0018130 24 24 0,000 0,16378534 0,18518796 ! nucleotide catabolic process GO:0009166 24 24 0,000 0,16378534 0,18507442 ! erythrocyte homeostasis GO:0034101 25 24 0,000 0,16378534 0,18496102 ! ovulation cycle GO:0042698 24 24 0,000 0,16378534 0,18484775 ! fertilization GO:0009566 25 24 0,000 0,16378534 0,18473463 ! oxidoreduction coenzyme metabolic process GO:0006733 24 24 0,000 0,16378534 0,18462164 ! androgen receptor signaling pathway GO:0030521 24 24 0,000 0,16378534 0,18450879 ! epithelial tube morphogenesis GO:0060562 25 24 0,000 0,16378534 0,18439608 ! glycoprotein metabolic process GO:0009100 99 98 1,000 0,16397 0,18449127 ! regulation of system process GO:0044057 98 98 1,000 0,16397 0,18437871 ! ectoderm development GO:0007398 99 99 1,000 0,16659623 0,18721759 ! response to other organism GO:0051707 101 100 1,000 0,16923008 0,19006157 ! regulation of actin filament polymerization GO:0030833 25 25 0,000 0,17000572 0,19081641 ! negative regulation of secretion GO:0051048 26 25 0,000 0,17000572 0,19070027 ! protein amino acid N-linked glycosylation GO:0006487 25 25 0,000 0,17000572 0,19058427 ! sensory perception of chemical stimulus GO:0007606 25 25 0,000 0,17000572 0,19046842 ! cellular component disassembly GO:0022411 26 25 0,000 0,17000572 0,1903527 ! polysaccharide biosynthetic process GO:0000271 25 25 0,000 0,17000572 0,19023713 ! excretion GO:0007588 25 25 0,000 0,17000572 0,19012169 ! generation of a signal involved in cell-cell signaling GO:0003001 27 25 0,000 0,17000572 0,1900064 ! gastrulation GO:0007369 25 25 0,000 0,17000572 0,18989124 ! icosanoid metabolic process GO:0006690 25 25 0,000 0,17000572 0,18977622 ! JAK-STAT cascade GO:0007259 26 25 0,000 0,17000572 0,18966135 ! glycolysis GO:0006096 26 26 0,000 0,17618074 0,19643139 ! transforming growth factor beta receptor signaling pathway GO:0007179 26 26 0,000 0,17618074 0,19631263 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 26 26 0,000 0,17618074 0,19619401 ! cellular defense response GO:0006968 26 26 0,000 0,17618074 0,19607554 ! positive regulation of cytokine biosynthetic process GO:0042108 26 26 0,000 0,17618074 0,19595721 ! germ cell development GO:0007281 27 26 0,000 0,17618074 0,19583902 ! pigment metabolic process GO:0042440 26 26 0,000 0,17618074 0,19572097 ! chloride transport GO:0006821 27 27 0,000 0,1823107 0,20240881 ! regulation of neurotransmitter levels GO:0001505 31 27 0,000 0,1823107 0,20228695 ! monocarboxylic acid transport GO:0015718 27 27 0,000 0,1823107 0,20216524 ! defense response to bacterium GO:0042742 27 27 0,000 0,1823107 0,20204367 ! glutamine family amino acid metabolic process GO:0009064 28 27 0,000 0,1823107 0,20192225 ! cell growth GO:0016049 27 27 0,000 0,1823107 0,20180097 ! tRNA aminoacylation for protein translation GO:0006418 28 28 0,000 0,18839594 0,2084116 GO:0043038|amino acid activation, GO:0043039|tRNA aminoacylation, ! stress-activated protein kinase signaling pathway GO:0031098 28 28 0,000 0,18839594 0,20828657 GO:0007254|JNK cascade, ! neuromuscular process GO:0050905 28 28 0,000 0,18839594 0,2081617 ! carbohydrate transport GO:0008643 28 28 0,000 0,18839594 0,20803698 ! regulation of muscle contraction GO:0006937 28 28 0,000 0,18839594 0,20791241 ! unsaturated fatty acid metabolic process GO:0033559 28 28 0,000 0,18839594 0,20778798 ! keratinocyte differentiation GO:0030216 28 28 0,000 0,18839594 0,20766371 ! developmental growth GO:0048589 28 28 0,000 0,18839594 0,20753958 ! glycerophospholipid biosynthetic process GO:0046474 30 29 0,000 0,19443678 0,2140663 ! leukocyte migration GO:0050900 30 29 0,000 0,19443678 0,2139385 ! branching morphogenesis of a tube GO:0048754 29 29 0,000 0,19443678 0,21381085 ! antigen processing and presentation GO:0019882 29 29 0,000 0,19443678 0,21368335 ! DNA-dependent DNA replication GO:0006261 29 29 0,000 0,19443678 0,21355601 ! tRNA processing GO:0008033 29 29 0,000 0,19443678 0,21342881 ! regulation of gene expression, epigenetic GO:0040029 29 29 0,000 0,19443678 0,21330177 ! adult behavior GO:0030534 30 29 0,000 0,19443678 0,21317488 ! regulation of protein polymerization GO:0032271 29 29 0,000 0,19443678 0,21304814 ! transition metal ion transport GO:0000041 31 30 0,000 0,20043353 0,21948841 ! RNA catabolic process GO:0006401 30 30 0,000 0,20043353 0,21935807 ! response to reactive oxygen species GO:0000302 31 30 0,000 0,20043353 0,21922789 ! ER to Golgi vesicle-mediated transport GO:0006888 30 30 0,000 0,20043353 0,21909786 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 30 30 0,000 0,20043353 0,21896798 ! neuropeptide signaling pathway GO:0007218 30 30 0,000 0,20043353 0,21883826 ! regulation of protein complex disassembly GO:0043244 30 30 0,000 0,20043353 0,2187087 ! response to temperature stimulus GO:0009266 30 30 0,000 0,20043353 0,21857928 ! regulation of ossification GO:0030278 30 30 0,000 0,20043353 0,21845002 ! immunoglobulin mediated immune response GO:0016064 30 30 0,000 0,20043353 0,21832091 GO:0019724|B cell mediated immunity, ! water-soluble vitamin metabolic process GO:0006767 30 30 0,000 0,20043353 0,21819196 ! vesicle organization GO:0016050 30 30 0,000 0,20043353 0,21806316 ! establishment of organelle localization GO:0051656 31 30 0,000 0,20043353 0,21793451 ! regulation of translational initiation GO:0006446 31 31 0,000 0,2063865 0,22427495 ! membrane fusion GO:0006944 31 31 0,000 0,2063865 0,2241428 ! negative regulation of cytoskeleton organization GO:0051494 32 31 0,000 0,2063865 0,22401079 ! lipoprotein metabolic process GO:0042157 31 31 0,000 0,2063865 0,22387894 ! ion transmembrane transport GO:0034220 31 31 0,000 0,2063865 0,22374725 GO:0015985|energy coupled proton transport, down electrochemical gradient, GO:0015986|ATP synthesis coupled proton transport, ! glycerolipid biosynthetic process GO:0045017 32 31 0,000 0,2063865 0,22361571 ! nucleoside metabolic process GO:0009116 31 31 0,000 0,2063865 0,22348433 ! regulation of heart contraction GO:0008016 31 31 0,000 0,2063865 0,2233531 ! sphingolipid metabolic process GO:0006665 31 31 0,000 0,2063865 0,22322202 ! extracellular matrix organization GO:0030198 31 31 0,000 0,2063865 0,2230911 ! epidermal cell differentiation GO:0009913 31 31 0,000 0,2063865 0,22296033 ! cell redox homeostasis GO:0045454 32 32 0,000 0,21229602 0,22921006 ! glucose catabolic process GO:0006007 32 32 0,000 0,21229602 0,22907586 ! glycosaminoglycan metabolic process GO:0030203 34 32 0,000 0,21229602 0,22894182 ! cell maturation GO:0048469 32 32 0,000 0,21229602 0,22880793 ! morphogenesis of a branching structure GO:0001763 32 32 0,000 0,21229602 0,22867421 ! nuclear export GO:0051168 32 32 0,000 0,21229602 0,22854063 ! protein maturation by peptide bond cleavage GO:0051605 32 32 0,000 0,21229602 0,22840722 ! regulation of cellular response to stress GO:0080135 35 33 0,000 0,21816239 0,23458185 ! regulation of protein complex assembly GO:0043254 33 33 0,000 0,21816239 0,23444506 ! membrane lipid metabolic process GO:0006643 33 33 0,000 0,21816239 0,23430844 ! regulation of actin polymerization or depolymerization GO:0008064 33 33 0,000 0,21816239 0,23417198 ! regulation of neuron differentiation GO:0045664 34 33 0,000 0,21816239 0,23403567 ! regulation of synaptic transmission GO:0050804 33 33 0,000 0,21816239 0,23389953 ! regulation of actin filament length GO:0030832 34 34 0,000 0,22398592 0,24000352 ! response to metal ion GO:0010038 34 34 0,000 0,22398592 0,23986406 ! muscle cell differentiation GO:0042692 35 34 0,000 0,22398592 0,23972477 ! nucleoside monophosphate biosynthetic process GO:0009124 34 34 0,000 0,22398592 0,23958564 ! regulation of lipid metabolic process GO:0019216 34 34 0,000 0,22398592 0,23944667 ! detection of stimulus GO:0051606 36 34 0,000 0,22398592 0,23930786 ! acute inflammatory response GO:0002526 35 35 0,000 0,22976692 0,24534208 ! regulation of cellular component size GO:0032535 35 35 0,000 0,22976692 0,24520002 ! regulation of cytokine biosynthetic process GO:0042035 35 35 0,000 0,22976692 0,24505812 ! mesoderm development GO:0007498 35 35 0,000 0,22976692 0,24491639 ! multicellular organism reproduction GO:0032504 36 35 0,000 0,22976692 0,24477482 GO:0048609|reproductive process in a multicellular organism, ! inorganic anion transport GO:0015698 35 35 0,000 0,22976692 0,24463341 ! response to steroid hormone stimulus GO:0048545 35 35 0,000 0,22976692 0,24449217 ! hydrogen transport GO:0006818 36 36 0,000 0,23550569 0,25045412 GO:0015992|proton transport, ! response to inorganic substance GO:0010035 36 36 0,000 0,23550569 0,25030968 ! aminoglycan metabolic process GO:0006022 38 36 0,000 0,23550569 0,25016541 ! regulation of mitosis GO:0007088 37 36 0,000 0,23550569 0,25002131 GO:0051783|regulation of nuclear division, ! embryonic limb morphogenesis GO:0030326 36 36 0,000 0,23550569 0,24987737 GO:0035113|embryonic appendage morphogenesis, ! female pregnancy GO:0007565 37 36 0,000 0,23550569 0,2497336 ! RNA elongation from RNA polymerase II promoter GO:0006368 36 36 0,000 0,23550569 0,24958999 ! positive regulation of organelle organization GO:0010638 36 36 0,000 0,23550569 0,24944655 ! heterocycle catabolic process GO:0046700 36 36 0,000 0,23550569 0,24930327 ! regulation of transmission of nerve impulse GO:0051969 36 36 0,000 0,23550569 0,24916015 ! gonad development GO:0008406 36 36 0,000 0,23550569 0,24901721 ! meiosis GO:0007126 37 37 0,000 0,24120254 0,25489465 GO:0051327|M phase of meiotic cell cycle, ! lymphocyte mediated immunity GO:0002449 37 37 0,000 0,24120254 0,25474858 ! ATP synthesis coupled electron transport GO:0042773 37 37 0,000 0,24120254 0,25460268 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! cellular amino acid catabolic process GO:0009063 38 37 0,000 0,24120254 0,25445694 ! regulation of Rho protein signal transduction GO:0035023 37 37 0,000 0,24120254 0,25431137 ! neurotransmitter transport GO:0006836 40 38 0,000 0,24685776 0,26012513 ! exocytosis GO:0006887 40 38 0,000 0,24685776 0,25997648 ! hexose catabolic process GO:0019320 38 38 0,000 0,24685776 0,25982801 ! RNA elongation GO:0006354 38 38 0,000 0,24685776 0,25967971 ! meiotic cell cycle GO:0051321 38 38 0,000 0,24685776 0,25953157 ! regulation of neurological system process GO:0031644 38 38 0,000 0,24685776 0,25938361 ! steroid hormone receptor signaling pathway GO:0030518 38 38 0,000 0,24685776 0,25923581 ! response to unfolded protein GO:0006986 39 39 0,000 0,25247165 0,26498021 ! nucleoside monophosphate metabolic process GO:0009123 39 39 0,000 0,25247165 0,2648294 ! fatty acid biosynthetic process GO:0006633 39 39 0,000 0,25247165 0,26467875 ! intracellular protein transmembrane transport GO:0065002 39 39 0,000 0,25247165 0,26452828 ! developmental maturation GO:0021700 39 39 0,000 0,25247165 0,26437798 ! limb development GO:0060173 39 39 0,000 0,25247165 0,26422785 GO:0048736|appendage development, GO:0035107|appendage morphogenesis, ! DNA catabolic process GO:0006308 41 40 0,000 0,25804451 0,26990694 ! intracellular receptor-mediated signaling pathway GO:0030522 40 40 0,000 0,25804451 0,26975385 ! myeloid cell differentiation GO:0030099 42 40 0,000 0,25804451 0,26960093 ! organelle localization GO:0051640 41 40 0,000 0,25804451 0,26944818 ! amine catabolic process GO:0009310 42 41 0,000 0,26357664 0,27506893 ! phospholipid biosynthetic process GO:0008654 42 41 0,000 0,26357664 0,27491326 ! leukocyte mediated immunity GO:0002443 41 41 0,000 0,26357664 0,27475777 ! monosaccharide catabolic process GO:0046365 41 41 0,000 0,26357664 0,27460245 ! respiratory electron transport chain GO:0022904 43 42 0,000 0,26906831 0,28016548 ! response to protein stimulus GO:0051789 42 42 0,000 0,26906831 0,28000729 ! forebrain development GO:0030900 43 42 0,000 0,26906831 0,27984927 ! alcohol catabolic process GO:0046164 43 43 0,000 0,27451984 0,28535818 ! homeostasis of number of cells GO:0048872 44 43 0,000 0,27451984 0,28519733 ! humoral immune response GO:0006959 44 44 0,000 0,27993149 0,29065563 ! mRNA transport GO:0051028 44 44 0,000 0,27993149 0,29049197 ! negative regulation of organelle organization GO:0010639 45 44 0,000 0,27993149 0,2903285 ! regulation of actin cytoskeleton organization GO:0032956 46 45 0,000 0,28530357 0,29573367 ! steroid biosynthetic process GO:0006694 46 45 0,000 0,28530357 0,29556744 ! protein processing GO:0016485 45 45 0,000 0,28530357 0,29540139 ! regulation of actin filament-based process GO:0032970 47 46 0,000 0,29063634 0,30075395 ! tube morphogenesis GO:0035239 47 46 0,000 0,29063634 0,30058517 ! transcription initiation from RNA polymerase II promoter GO:0006367 46 46 0,000 0,29063634 0,30041659 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 47 47 0,000 0,2959301 0,30571703 ! rhythmic process GO:0048511 47 47 0,000 0,2959301 0,30554576 ! DNA recombination GO:0006310 48 48 0,000 0,30118512 0,31079741 ! cellular lipid catabolic process GO:0044242 50 49 0,000 0,30640168 0,31600353 ! response to bacterium GO:0009617 50 49 0,000 0,30640168 0,31582679 ! chromatin assembly GO:0031497 50 50 0,000 0,31158006 0,32098494 GO:0006334|nucleosome assembly, ! RNA transport GO:0050658 50 50 0,000 0,31158006 0,32080562 GO:0050657|nucleic acid transport, GO:0051236|establishment of RNA localization, ! nitrogen compound catabolic process GO:0044270 51 50 0,000 0,31158006 0,3206265 ! transcription initiation GO:0006352 50 50 0,000 0,31158006 0,32044758 ! biogenic amine metabolic process GO:0006576 52 51 0,000 0,31672054 0,32555268 ! rRNA metabolic process GO:0016072 51 51 0,000 0,31672054 0,32537121 GO:0006364|rRNA processing, ! protein-DNA complex assembly GO:0065004 51 51 0,000 0,31672054 0,32518994 ! ATP biosynthetic process GO:0006754 51 51 0,000 0,31672054 0,32500888 ! protein maturation GO:0051604 51 51 0,000 0,31672054 0,32482802 ! RNA localization GO:0006403 52 52 0,000 0,32182337 0,3298779 ! cholesterol metabolic process GO:0008203 52 52 0,000 0,32182337 0,32969454 ! tRNA metabolic process GO:0006399 53 53 0,000 0,32688884 0,33469785 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 53 53 0,000 0,32688884 0,33451201 ! carbohydrate catabolic process GO:0016052 53 53 0,000 0,32688884 0,33432637 ! nucleosome organization GO:0034728 55 55 0,000 0,33690874 0,34438314 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 55 55 0,000 0,33690874 0,34419224 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! microtubule cytoskeleton organization GO:0000226 55 55 0,000 0,33690874 0,34400156 ! ribonucleoside triphosphate biosynthetic process GO:0009201 56 56 0,000 0,34186371 0,34886756 ! ATP metabolic process GO:0046034 57 57 0,000 0,34678237 0,35369115 ! nucleoside triphosphate biosynthetic process GO:0009142 57 57 0,000 0,34678237 0,35349552 ! innate immune response GO:0045087 58 58 0,000 0,35166499 0,3582745 ! sterol metabolic process GO:0016125 59 59 0,000 0,35651182 0,36301176 ! cellular aromatic compound metabolic process GO:0006725 60 59 0,000 0,35651182 0,36281131 ! potassium ion transport GO:0006813 60 60 0,000 0,36132312 0,3675047 ! cellular respiration GO:0045333 62 61 0,000 0,36609915 0,37215705 ! carboxylic acid catabolic process GO:0046395 63 61 0,000 0,36609915 0,37195189 GO:0016054|organic acid catabolic process, ! purine ribonucleoside triphosphate metabolic process GO:0009205 62 62 0,000 0,37084016 0,37656111 ! morphogenesis of an epithelium GO:0002009 63 62 0,000 0,37084016 0,37635375 GO:0060429|epithelium development, ! ribonucleoside triphosphate metabolic process GO:0009199 63 63 0,000 0,3755464 0,38092021 ! purine nucleoside triphosphate metabolic process GO:0009144 63 63 0,000 0,3755464 0,38071068 ! regulation of cytoskeleton organization GO:0051493 66 64 0,000 0,38021813 0,38523475 ! protein amino acid glycosylation GO:0006486 66 66 0,000 0,38945901 0,39438074 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! nucleoside triphosphate metabolic process GO:0009141 66 66 0,000 0,38945901 0,39416417 ! DNA packaging GO:0006323 66 66 0,000 0,38945901 0,39394783 ! muscle contraction GO:0006936 67 67 0,000 0,39402866 0,39835152 ! purine ribonucleotide biosynthetic process GO:0009152 68 68 0,000 0,39856477 0,40271648 ! chromatin assembly or disassembly GO:0006333 68 68 0,000 0,39856477 0,40249582 ! regulation of translation GO:0006417 69 69 0,000 0,40306759 0,40682013 ! sensory perception of sound GO:0007605 71 69 0,000 0,40306759 0,40659746 GO:0050954|sensory perception of mechanical stimulus, ! growth GO:0040007 70 70 0,000 0,40753735 0,41088147 ! oxidative phosphorylation GO:0006119 71 71 0,000 0,41197429 0,41512773 ! ribosome biogenesis GO:0042254 71 71 0,000 0,41197429 0,41490089 ! secretion by cell GO:0032940 75 72 0,000 0,41637866 0,41910752 ! electron transport chain GO:0022900 75 74 0,000 0,42509058 0,42764298 ! ribonucleotide biosynthetic process GO:0009260 75 75 0,000 0,4293986 0,4317412 ! purine ribonucleotide metabolic process GO:0009150 75 75 0,000 0,4293986 0,43150579 ! glycoprotein biosynthetic process GO:0009101 80 80 0,000 0,45046843 0,45243232 ! lipid catabolic process GO:0016042 82 81 0,000 0,45458992 0,4563231 ! ribonucleotide metabolic process GO:0009259 83 83 0,000 0,46274218 0,46425358 ! ncRNA processing GO:0034470 83 83 0,000 0,46274218 0,464001 ! purine nucleotide biosynthetic process GO:0006164 88 88 0,000 0,48260378 0,48365349 ! brain development GO:0007420 91 90 0,000 0,49034526 0,49114474 ! fatty acid metabolic process GO:0006631 93 92 0,000 0,49797315 0,49851413 ! tissue morphogenesis GO:0048729 94 93 0,000 0,50174501 0,5020174 ! endocytosis GO:0006897 99 98 0,000 0,52019148 0,52019148 GO:0010324|membrane invagination,