pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6830-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 8,000 2,563E-11 6,168E-08 ! response to UV GO:0009411 104 53 7,000 4,918E-10 5,916E-07 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 4,000 2,089E-09 1,676E-06 GO:0010812|negative regulation of cell-substrate adhesion, ! glutathione biosynthetic process GO:0006750 13 11 4,000 2,089E-09 1,257E-06 ! negative regulation of phosphorylation GO:0042326 47 24 5,000 3,061E-09 1,473E-06 ! lung development GO:0030324 144 67 7,000 3,392E-09 1,36E-06 ! positive regulation of cellular catabolic process GO:0031331 31 12 4,000 3,566E-09 1,226E-06 ! phospholipid dephosphorylation GO:0046839 12 5 3,000 4,325E-09 1,301E-06 ! positive regulation of glycolysis GO:0045821 14 5 3,000 4,325E-09 1,156E-06 ! respiratory tube development GO:0030323 150 70 7,000 4,841E-09 1,165E-06 ! induction of apoptosis by intracellular signals GO:0008629 93 45 6,000 4,966E-09 1,086E-06 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 5,000 5,189E-09 1,04E-06 GO:0045936|negative regulation of phosphate metabolic process, ! respiratory system development GO:0060541 153 72 7,000 6,081E-09 1,125E-06 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 3,000 1,292E-08 2,22E-06 ! auditory receptor cell differentiation GO:0042491 32 16 4,000 1,932E-08 3,099E-06 ! positive regulation of catabolic process GO:0009896 64 32 5,000 1,988E-08 2,989E-06 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 4,000 2,725E-08 3,857E-06 ! cardiac muscle tissue development GO:0048738 31 17 4,000 2,725E-08 3,643E-06 ! negative regulation of focal adhesion formation GO:0051895 20 7 3,000 3,002E-08 3,801E-06 ! peptide biosynthetic process GO:0043043 24 18 4,000 3,756E-08 4,519E-06 ! regulation of protein stability GO:0031647 73 37 5,000 4,985E-08 5,712E-06 ! regulation of focal adhesion formation GO:0051893 22 8 3,000 5,978E-08 6,537E-06 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 3,000 5,978E-08 6,253E-06 ! positive regulation of cell motion GO:0051272 146 64 6,000 6,23E-08 6,245E-06 ! inner ear receptor cell differentiation GO:0060113 37 20 4,000 6,737E-08 6,484E-06 ! negative regulation of protein kinase activity GO:0006469 130 67 6,000 8,602E-08 7,96E-06 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 4,000 8,804E-08 7,845E-06 ! negative regulation of kinase activity GO:0033673 131 68 6,000 9,545E-08 8,202E-06 ! positive regulation of glucose metabolic process GO:0010907 18 9 3,000 1,071E-07 8,889E-06 ! induction of positive chemotaxis GO:0050930 15 9 3,000 1,071E-07 8,592E-06 ! regulation of glycolysis GO:0006110 21 9 3,000 1,071E-07 8,315E-06 ! mechanoreceptor differentiation GO:0042490 40 22 4,000 1,134E-07 8,528E-06 ! negative regulation of transferase activity GO:0051348 140 72 6,000 1,424E-07 1,038E-05 ! regulation of cell-matrix adhesion GO:0001952 78 23 4,000 1,443E-07 1,021E-05 GO:0010810|regulation of cell-substrate adhesion, ! regulation of protein kinase B signaling cascade GO:0051896 26 10 3,000 1,778E-07 1,222E-05 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 3,000 1,778E-07 1,188E-05 GO:0043470|regulation of carbohydrate catabolic process, ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 3,000 1,778E-07 1,156E-05 ! regulation of cellular catabolic process GO:0031329 52 24 4,000 1,815E-07 1,149E-05 ! regulation of oxidoreductase activity GO:0051341 46 24 4,000 1,815E-07 1,119E-05 ! regulation of catabolic process GO:0009894 161 76 6,000 2,075E-07 1,248E-05 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 3,000 2,782E-07 1,633E-05 ! positive regulation of endothelial cell proliferation GO:0001938 22 11 3,000 2,782E-07 1,594E-05 ! insulin receptor signaling pathway GO:0008286 64 26 4,000 2,784E-07 1,558E-05 ! glutathione metabolic process GO:0006749 39 27 4,000 3,401E-07 1,86E-05 ! regulation of B cell proliferation GO:0030888 20 12 3,000 4,155E-07 2,222E-05 ! regulation of positive chemotaxis GO:0050926 19 12 3,000 4,155E-07 2,173E-05 GO:0050927|positive regulation of positive chemotaxis, ! negative regulation of cell motion GO:0051271 134 55 5,000 5,73E-07 2,933E-05 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 3,000 5,976E-07 2,996E-05 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of monooxygenase activity GO:0032768 33 13 3,000 5,976E-07 2,934E-05 ! positive regulation of cell migration GO:0030335 126 57 5,000 7,109E-07 3,421E-05 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 3,000 8,331E-07 3,93E-05 ! positive regulation of oxidoreductase activity GO:0051353 22 15 3,000 1,131E-06 5,234E-05 ! regulation of homeostatic process GO:0032844 134 62 5,000 1,177E-06 5,345E-05 ! negative regulation of cell adhesion GO:0007162 81 35 4,000 1,32E-06 5,882E-05 ! regulation of glucose metabolic process GO:0010906 28 16 3,000 1,502E-06 6,57E-05 ! L-serine biosynthetic process GO:0006564 6 5 2,000 1,602E-06 6,882E-05 ! mRNA transcription GO:0009299 9 5 2,000 1,602E-06 6,761E-05 ! cellular response to insulin stimulus GO:0032869 82 37 4,000 1,757E-06 7,288E-05 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 5,000 1,869E-06 7,62E-05 ! endothelial cell migration GO:0043542 28 17 3,000 1,956E-06 7,842E-05 ! inositol metabolic process GO:0006020 28 17 3,000 1,956E-06 7,713E-05 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 3,000 1,956E-06 7,589E-05 ! carbohydrate homeostasis GO:0033500 53 38 4,000 2,014E-06 7,692E-05 GO:0042593|glucose homeostasis, ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 3,000 2,504E-06 9,412E-05 ! regulation of hormone biosynthetic process GO:0046885 10 6 2,000 3,191E-06 1,181E-04 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 2,000 3,191E-06 1,163E-04 ! response to UV-C GO:0010225 11 6 2,000 3,191E-06 1,146E-04 ! regulation of intracellular protein transport GO:0033157 80 42 4,000 3,354E-06 1,187E-04 ! positive regulation of response to external stimulus GO:0032103 77 43 4,000 3,778E-06 1,317E-04 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 3,000 3,93E-06 1,351E-04 ! regulation of carbohydrate metabolic process GO:0006109 38 20 3,000 3,93E-06 1,332E-04 GO:0010675|regulation of cellular carbohydrate metabolic process, ! apoptotic mitochondrial changes GO:0008637 41 20 3,000 3,93E-06 1,313E-04 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 3,000 3,93E-06 1,295E-04 ! positive regulation of locomotion GO:0040017 39 21 3,000 4,834E-06 1,572E-04 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! positive regulation of inflammatory response GO:0050729 35 21 3,000 4,834E-06 1,551E-04 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 4,000 5,309E-06 1,681E-04 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 4,000 5,309E-06 1,659E-04 ! regulation of gene-specific transcription GO:0032583 96 46 4,000 5,309E-06 1,638E-04 ! response to insulin stimulus GO:0032868 95 46 4,000 5,309E-06 1,617E-04 ! positive regulation of protein transport GO:0051222 72 46 4,000 5,309E-06 1,597E-04 ! regulation of protein export from nucleus GO:0046825 10 7 2,000 5,561E-06 1,652E-04 ! N-terminal protein amino acid acetylation GO:0006474 13 7 2,000 5,561E-06 1,632E-04 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 2,000 5,561E-06 1,612E-04 ! positive regulation of monooxygenase activity GO:0032770 12 7 2,000 5,561E-06 1,593E-04 ! response to hypoxia GO:0001666 171 81 5,000 5,704E-06 1,615E-04 ! regulation of chemotaxis GO:0050920 40 22 3,000 5,883E-06 1,646E-04 ! positive regulation of intracellular transport GO:0032388 37 22 3,000 5,883E-06 1,627E-04 ! regulation of inflammatory response GO:0050727 75 48 4,000 6,574E-06 1,797E-04 ! regulation of mast cell proliferation GO:0070666 81 48 4,000 6,574E-06 1,777E-04 ! response to oxygen levels GO:0070482 176 83 5,000 6,575E-06 1,758E-04 ! negative regulation of transport GO:0051051 153 84 5,000 7,049E-06 1,864E-04 ! peptide metabolic process GO:0006518 76 49 4,000 7,289E-06 1,906E-04 ! inner ear development GO:0048839 79 50 4,000 8,063E-06 2,086E-04 ! regulation of behavior GO:0050795 43 24 3,000 8,473E-06 2,169E-04 ! protein tetramerization GO:0051262 52 24 3,000 8,473E-06 2,146E-04 ! regulation of protein transport GO:0051223 154 87 5,000 8,639E-06 2,165E-04 GO:0070201|regulation of establishment of protein localization, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 2,000 8,862E-06 2,198E-04 ! ER overload response GO:0006983 12 8 2,000 8,862E-06 2,176E-04 ! positive regulation of endothelial cell migration GO:0010595 19 8 2,000 8,862E-06 2,154E-04 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 2,000 8,862E-06 2,132E-04 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 2,000 8,862E-06 2,111E-04 ! regulation of leukocyte proliferation GO:0070663 88 51 4,000 8,9E-06 2,099E-04 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! cartilage development GO:0051216 90 52 4,000 9,803E-06 2,29E-04 ! regulation of cell adhesion GO:0030155 212 89 5,000 9,852E-06 2,279E-04 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 3,000 1,004E-05 2,302E-04 ! regulation of endothelial cell proliferation GO:0001936 57 26 3,000 1,182E-05 2,683E-04 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 4,000 1,182E-05 2,659E-04 ! sulfur compound biosynthetic process GO:0044272 93 55 4,000 1,295E-05 2,885E-04 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 2,000 1,324E-05 2,922E-04 ! motor axon guidance GO:0008045 16 9 2,000 1,324E-05 2,896E-04 ! positive regulation of erythrocyte differentiation GO:0045648 29 9 2,000 1,324E-05 2,87E-04 ! regulation of fibroblast proliferation GO:0048145 52 27 3,000 1,382E-05 2,968E-04 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 3,000 1,382E-05 2,942E-04 ! lipid modification GO:0030258 97 57 4,000 1,545E-05 3,261E-04 ! regulation of intracellular transport GO:0032386 101 57 4,000 1,545E-05 3,232E-04 ! negative regulation of protein modification process GO:0031400 60 28 3,000 1,605E-05 3,329E-04 ! regulation of DNA metabolic process GO:0051052 178 97 5,000 1,616E-05 3,323E-04 ! regulation of protein localization GO:0032880 176 97 5,000 1,616E-05 3,295E-04 ! Golgi vesicle transport GO:0048193 207 99 5,000 1,816E-05 3,672E-04 ! cellular response to extracellular stimulus GO:0031668 48 29 3,000 1,854E-05 3,717E-04 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 2,000 1,884E-05 3,746E-04 ! positive regulation of B cell proliferation GO:0030890 16 10 2,000 1,884E-05 3,715E-04 ! L-serine metabolic process GO:0006563 18 10 2,000 1,884E-05 3,685E-04 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 2,000 1,884E-05 3,655E-04 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 2,000 1,884E-05 3,626E-04 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 2,000 1,884E-05 3,597E-04 ! cell cycle arrest GO:0007050 213 100 5,000 1,923E-05 3,643E-04 ! protein amino acid autophosphorylation GO:0046777 141 60 4,000 1,989E-05 3,738E-04 ! negative regulation of response to stimulus GO:0048585 100 60 4,000 1,989E-05 3,709E-04 ! negative regulation of protein kinase cascade GO:0010741 68 30 3,000 2,13E-05 3,942E-04 ! regulation of B cell activation GO:0050864 50 30 3,000 2,13E-05 3,912E-04 ! response to peptide hormone stimulus GO:0043434 122 61 4,000 2,157E-05 3,931E-04 ! ear development GO:0043583 103 62 4,000 2,335E-05 4,225E-04 ! blood vessel remodeling GO:0001974 29 11 2,000 2,58E-05 4,632E-04 ! peptide or protein amino-terminal blocking GO:0018409 21 11 2,000 2,58E-05 4,598E-04 ! chondrocyte differentiation GO:0002062 24 11 2,000 2,58E-05 4,564E-04 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 2,000 2,58E-05 4,531E-04 ! negative regulation of glucose import GO:0046325 17 11 2,000 2,58E-05 4,498E-04 GO:0010829|negative regulation of glucose transport, ! spliceosome assembly GO:0000245 67 32 3,000 2,771E-05 4,797E-04 ! positive regulation of gene-specific transcription GO:0043193 65 33 3,000 3,14E-05 5,396E-04 ! negative regulation of protein transport GO:0051224 69 33 3,000 3,14E-05 5,358E-04 ! focal adhesion formation GO:0048041 35 12 2,000 3,426E-05 5,805E-04 ! histone acetylation GO:0016573 26 12 2,000 3,426E-05 5,764E-04 ! regulation of hormone metabolic process GO:0032350 26 12 2,000 3,426E-05 5,724E-04 ! peptidyl-lysine modification GO:0018205 21 12 2,000 3,426E-05 5,684E-04 ! regulation of RNA splicing GO:0043484 20 12 2,000 3,426E-05 5,646E-04 ! negative regulation of mast cell proliferation GO:0070667 23 12 2,000 3,426E-05 5,607E-04 GO:0042130|negative regulation of T cell proliferation, ! placenta development GO:0001890 53 34 3,000 3,544E-05 5,761E-04 ! negative regulation of cell size GO:0045792 134 69 4,000 3,933E-05 6,351E-04 ! coenzyme biosynthetic process GO:0009108 102 69 4,000 3,933E-05 6,308E-04 ! response to X-ray GO:0010165 25 13 2,000 4,436E-05 7,068E-04 ! serine family amino acid biosynthetic process GO:0009070 17 13 2,000 4,436E-05 7,021E-04 ! embryonic placenta development GO:0001892 23 13 2,000 4,436E-05 6,975E-04 ! phosphoinositide metabolic process GO:0030384 128 72 4,000 4,832E-05 7,549E-04 ! tissue remodeling GO:0048771 76 37 3,000 4,982E-05 7,734E-04 ! regulation of transcription factor activity GO:0051090 126 74 4,000 5,514E-05 8,505E-04 GO:0090046|regulation of transcription regulator activity, ! N-terminal protein amino acid modification GO:0031365 27 14 2,000 5,623E-05 8,617E-04 ! regulation of S phase GO:0033261 23 14 2,000 5,623E-05 8,562E-04 ! regulation of mRNA processing GO:0050684 24 14 2,000 5,623E-05 8,508E-04 ! response to gamma radiation GO:0010332 28 14 2,000 5,623E-05 8,455E-04 ! regulation of erythrocyte differentiation GO:0045646 44 14 2,000 5,623E-05 8,402E-04 ! regulation of the force of heart contraction GO:0002026 26 15 2,000 7E-05 1,04E-03 ! regulation of T cell proliferation GO:0042129 71 41 3,000 7,51E-05 1,109E-03 ! T cell differentiation GO:0030217 81 41 3,000 7,51E-05 1,102E-03 ! regulation of T cell differentiation GO:0045580 70 41 3,000 7,51E-05 1,095E-03 ! polyol metabolic process GO:0019751 66 41 3,000 7,51E-05 1,089E-03 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 4,000 7,547E-05 1,087E-03 ! positive regulation of phosphorylation GO:0042327 129 79 4,000 7,547E-05 1,081E-03 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 4,000 8,504E-05 1,211E-03 GO:0045937|positive regulation of phosphate metabolic process, ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 2,000 8,581E-05 1,214E-03 ! positive regulation of protein import into nucleus GO:0042307 30 16 2,000 8,581E-05 1,207E-03 ! negative regulation of leukocyte proliferation GO:0070664 31 16 2,000 8,581E-05 1,2E-03 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! cellular response to hormone stimulus GO:0032870 167 82 4,000 9,017E-05 1,254E-03 ! regulation of epithelial cell proliferation GO:0050678 111 43 3,000 9,075E-05 1,255E-03 ! negative regulation of growth GO:0045926 155 84 4,000 1,011E-04 1,39E-03 ! regulation of ligase activity GO:0051340 142 84 4,000 1,011E-04 1,382E-03 ! neural crest cell migration GO:0001755 37 17 2,000 1,038E-04 1,411E-03 ! neutrophil chemotaxis GO:0030593 27 17 2,000 1,038E-04 1,403E-03 ! negative regulation of cell migration GO:0030336 115 46 3,000 1,185E-04 1,592E-03 ! cell-substrate junction assembly GO:0007044 54 18 2,000 1,24E-04 1,658E-03 ! peptidyl-serine phosphorylation GO:0018105 38 18 2,000 1,24E-04 1,649E-03 ! regulation of immunoglobulin production GO:0002637 43 18 2,000 1,24E-04 1,64E-03 ! regulation of DNA binding GO:0051101 155 88 4,000 1,261E-04 1,658E-03 ! positive regulation of defense response GO:0031349 76 47 3,000 1,289E-04 1,686E-03 ! positive regulation of cell cycle GO:0045787 89 48 3,000 1,401E-04 1,822E-03 ! regulation of lymphocyte differentiation GO:0045619 81 48 3,000 1,401E-04 1,812E-03 ! ossification GO:0001503 188 90 4,000 1,402E-04 1,804E-03 ! actin filament bundle formation GO:0051017 42 19 2,000 1,467E-04 1,877E-03 ! regulation of endothelial cell migration GO:0010594 44 19 2,000 1,467E-04 1,867E-03 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 2,000 1,467E-04 1,858E-03 ! bone development GO:0060348 189 91 4,000 1,477E-04 1,861E-03 ! cofactor biosynthetic process GO:0051188 139 91 4,000 1,477E-04 1,851E-03 ! ribonucleoprotein complex assembly GO:0022618 95 49 3,000 1,519E-04 1,893E-03 ! regulation of defense response GO:0031347 149 92 4,000 1,555E-04 1,929E-03 ! positive regulation of MAP kinase activity GO:0043406 160 93 4,000 1,636E-04 2,019E-03 ! negative regulation of immune system process GO:0002683 95 50 3,000 1,644E-04 2,018E-03 ! positive regulation of cytokine production GO:0001819 86 50 3,000 1,644E-04 2,008E-03 ! protein amino acid acetylation GO:0006473 39 20 2,000 1,719E-04 2,089E-03 ! cellular response to starvation GO:0009267 33 20 2,000 1,719E-04 2,078E-03 ! peptidyl-serine modification GO:0018209 43 20 2,000 1,719E-04 2,068E-03 ! regulation of glucose import GO:0046324 29 20 2,000 1,719E-04 2,057E-03 GO:0010827|regulation of glucose transport, ! negative regulation of T cell activation GO:0050868 40 20 2,000 1,719E-04 2,047E-03 ! interphase of mitotic cell cycle GO:0051329 209 95 4,000 1,808E-04 2,143E-03 ! inactivation of MAPK activity GO:0000188 39 21 2,000 1,997E-04 2,356E-03 ! cell aging GO:0007569 44 21 2,000 1,997E-04 2,344E-03 ! negative regulation of intracellular transport GO:0032387 41 21 2,000 1,997E-04 2,333E-03 ! interphase GO:0051325 213 98 4,000 2,092E-04 2,431E-03 ! activation of phospholipase C activity GO:0007202 103 54 3,000 2,219E-04 2,567E-03 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of protein catabolic process GO:0045732 38 22 2,000 2,303E-04 2,652E-03 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 2,000 2,303E-04 2,639E-03 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 2,000 2,303E-04 2,626E-03 ! positive regulation of B cell activation GO:0050871 38 22 2,000 2,303E-04 2,614E-03 ! positive regulation of caspase activity GO:0043280 95 55 3,000 2,383E-04 2,692E-03 GO:0010952|positive regulation of peptidase activity, ! positive regulation of phospholipase activity GO:0010518 104 55 3,000 2,383E-04 2,679E-03 ! regulation of protein catabolic process GO:0042176 116 55 3,000 2,383E-04 2,667E-03 ! aging GO:0007568 103 55 3,000 2,383E-04 2,654E-03 ! heart morphogenesis GO:0003007 97 55 3,000 2,383E-04 2,642E-03 ! regulation of DNA replication GO:0006275 101 56 3,000 2,555E-04 2,82E-03 ! regulation of phospholipase activity GO:0010517 106 57 3,000 2,737E-04 3,007E-03 ! positive regulation of lipase activity GO:0060193 108 58 3,000 2,927E-04 3,201E-03 ! hemoglobin biosynthetic process GO:0042541 7 5 1,000 2,951E-04 3,213E-03 ! negative regulation of bone resorption GO:0045779 10 5 1,000 2,951E-04 3,199E-03 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 1,000 2,951E-04 3,184E-03 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 1,000 2,951E-04 3,17E-03 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 1,000 2,951E-04 3,156E-03 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 1,000 2,951E-04 3,142E-03 ! anagen GO:0042640 6 5 1,000 2,951E-04 3,128E-03 ! microvillus organization GO:0032528 7 5 1,000 2,951E-04 3,114E-03 GO:0030033|microvillus assembly, ! response to food GO:0032094 6 5 1,000 2,951E-04 3,101E-03 ! positive regulation of transporter activity GO:0032411 8 5 1,000 2,951E-04 3,087E-03 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 1,000 2,951E-04 3,074E-03 ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 2,951E-04 3,061E-03 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 1,000 2,951E-04 3,048E-03 ! cellular glucose homeostasis GO:0001678 5 5 1,000 2,951E-04 3,035E-03 ! early endosome to late endosome transport GO:0045022 12 5 1,000 2,951E-04 3,022E-03 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 1,000 2,951E-04 3,009E-03 ! negative regulation of T cell mediated immunity GO:0002710 12 5 1,000 2,951E-04 2,996E-03 GO:0002707|negative regulation of lymphocyte mediated immunity, ! positive regulation of chemokine production GO:0032722 8 5 1,000 2,951E-04 2,984E-03 ! enteric nervous system development GO:0048484 8 5 1,000 2,951E-04 2,971E-03 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 1,000 2,951E-04 2,959E-03 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 1,000 2,951E-04 2,946E-03 ! inner cell mass cell proliferation GO:0001833 5 5 1,000 2,951E-04 2,934E-03 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 1,000 2,951E-04 2,922E-03 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 1,000 2,951E-04 2,91E-03 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! stem cell division GO:0017145 11 5 1,000 2,951E-04 2,898E-03 GO:0048103|somatic stem cell division, ! protein import into nucleus, translocation GO:0000060 46 24 2,000 3,003E-04 2,937E-03 ! positive regulation of fibroblast proliferation GO:0048146 43 24 2,000 3,003E-04 2,925E-03 ! DNA damage response, signal transduction GO:0042770 128 60 3,000 3,336E-04 3,236E-03 ! negative regulation of DNA replication GO:0008156 42 25 2,000 3,399E-04 3,284E-03 ! response to starvation GO:0042594 42 25 2,000 3,399E-04 3,271E-03 ! response to endoplasmic reticulum stress GO:0034976 43 25 2,000 3,399E-04 3,258E-03 ! neural crest cell development GO:0014032 54 25 2,000 3,399E-04 3,245E-03 GO:0014033|neural crest cell differentiation, ! cellular response to nutrient levels GO:0031669 41 25 2,000 3,399E-04 3,232E-03 ! regulation of transcription factor import into nucleus GO:0042990 54 26 2,000 3,827E-04 3,625E-03 ! cellular response to oxidative stress GO:0034599 39 26 2,000 3,827E-04 3,611E-03 ! protein amino acid acylation GO:0043543 55 27 2,000 4,288E-04 4,03E-03 ! negative regulation of lymphocyte activation GO:0051250 53 27 2,000 4,288E-04 4,014E-03 ! male meiosis GO:0007140 7 6 1,000 4,411E-04 4,113E-03 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 1,000 4,411E-04 4,098E-03 ! embryonic hemopoiesis GO:0035162 14 6 1,000 4,411E-04 4,082E-03 ! cGMP-mediated signaling GO:0019934 13 6 1,000 4,411E-04 4,066E-03 ! activation of MAPKKK activity GO:0000185 12 6 1,000 4,411E-04 4,051E-03 ! thymic T cell selection GO:0045061 12 6 1,000 4,411E-04 4,035E-03 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 1,000 4,411E-04 4,02E-03 ! positive regulation of muscle hypertrophy GO:0014742 10 6 1,000 4,411E-04 4,005E-03 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! male sex determination GO:0030238 15 6 1,000 4,411E-04 3,99E-03 ! regulation of immunoglobulin secretion GO:0051023 6 6 1,000 4,411E-04 3,975E-03 ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 1,000 4,411E-04 3,96E-03 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 1,000 4,411E-04 3,945E-03 ! hair follicle maturation GO:0048820 7 6 1,000 4,411E-04 3,931E-03 ! negative regulation of neuroblast proliferation GO:0007406 21 6 1,000 4,411E-04 3,916E-03 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 1,000 4,411E-04 3,902E-03 ! negative regulation of B cell activation GO:0050869 13 6 1,000 4,411E-04 3,887E-03 ! ER-nuclear signaling pathway GO:0006984 48 28 2,000 4,783E-04 4,2E-03 ! actin filament organization GO:0007015 148 66 3,000 4,806E-04 4,205E-03 ! developmental maturation GO:0021700 116 66 3,000 4,806E-04 4,189E-03 ! negative regulation of cell growth GO:0030308 132 67 3,000 5,089E-04 4,421E-03 ! regulation of production of molecular mediator of immune response GO:0002700 61 29 2,000 5,314E-04 4,599E-03 ! tissue homeostasis GO:0001894 48 29 2,000 5,314E-04 4,582E-03 GO:0048871|multicellular organismal homeostasis, ! negative regulation of ligase activity GO:0051352 112 68 3,000 5,384E-04 4,627E-03 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! regulation of lipase activity GO:0060191 130 68 3,000 5,384E-04 4,61E-03 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 3,000 5,384E-04 4,594E-03 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 3,000 5,692E-04 4,839E-03 ! urogenital system development GO:0001655 137 69 3,000 5,692E-04 4,822E-03 ! cell junction assembly GO:0034329 78 30 2,000 5,88E-04 4,964E-03 ! negative regulation of leukocyte activation GO:0002695 56 30 2,000 5,88E-04 4,947E-03 ! regulation of helicase activity GO:0051095 15 7 1,000 6,153E-04 5,158E-03 ! cytokinesis during cell cycle GO:0033205 11 7 1,000 6,153E-04 5,14E-03 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 1,000 6,153E-04 5,123E-03 ! Golgi to plasma membrane transport GO:0006893 14 7 1,000 6,153E-04 5,105E-03 ! mRNA stabilization GO:0048255 18 7 1,000 6,153E-04 5,087E-03 GO:0043489|RNA stabilization, ! positive regulation of isotype switching GO:0045830 15 7 1,000 6,153E-04 5,07E-03 GO:0045911|positive regulation of DNA recombination, ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 1,000 6,153E-04 5,053E-03 ! induction of apoptosis by oxidative stress GO:0008631 8 7 1,000 6,153E-04 5,036E-03 ! positive regulation of mitotic cell cycle GO:0045931 12 7 1,000 6,153E-04 5,018E-03 ! centrosome duplication GO:0051298 13 7 1,000 6,153E-04 5,001E-03 ! G1 DNA damage checkpoint GO:0031571 21 7 1,000 6,153E-04 4,985E-03 ! B cell lineage commitment GO:0002326 21 7 1,000 6,153E-04 4,968E-03 ! T cell lineage commitment GO:0002360 16 7 1,000 6,153E-04 4,951E-03 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 1,000 6,153E-04 4,935E-03 GO:0002714|positive regulation of B cell mediated immunity, ! oxygen homeostasis GO:0032364 12 7 1,000 6,153E-04 4,918E-03 ! response to tumor cell GO:0002347 13 7 1,000 6,153E-04 4,902E-03 ! regulation of respiratory burst GO:0060263 11 7 1,000 6,153E-04 4,886E-03 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 1,000 6,153E-04 4,87E-03 ! muscle adaptation GO:0043500 14 7 1,000 6,153E-04 4,854E-03 ! serine family amino acid metabolic process GO:0009069 49 31 2,000 6,484E-04 5,098E-03 ! negative regulation of transcription regulator activity GO:0090048 58 31 2,000 6,484E-04 5,082E-03 GO:0043433|negative regulation of transcription factor activity, ! regulation of caspase activity GO:0043281 122 72 3,000 6,688E-04 5,224E-03 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 3,000 6,688E-04 5,207E-03 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 3,000 6,688E-04 5,19E-03 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 3,000 6,688E-04 5,174E-03 ! learning or memory GO:0007611 147 73 3,000 7,045E-04 5,433E-03 ! response to ionizing radiation GO:0010212 65 32 2,000 7,126E-04 5,478E-03 ! regulation of protein import into nucleus GO:0042306 63 32 2,000 7,126E-04 5,46E-03 ! negative regulation of MAP kinase activity GO:0043407 69 32 2,000 7,126E-04 5,443E-03 ! regulation of endopeptidase activity GO:0052548 125 74 3,000 7,416E-04 5,647E-03 ! cell-matrix adhesion GO:0007160 163 75 3,000 7,801E-04 5,921E-03 ! phosphoinositide-mediated signaling GO:0048015 131 75 3,000 7,801E-04 5,902E-03 ! lymphocyte differentiation GO:0030098 167 75 3,000 7,801E-04 5,884E-03 ! leukocyte chemotaxis GO:0030595 50 33 2,000 7,808E-04 5,87E-03 GO:0060326|cell chemotaxis, ! T-helper 1 type immune response GO:0042088 12 8 1,000 8,175E-04 6,127E-03 ! hemoglobin metabolic process GO:0020027 13 8 1,000 8,175E-04 6,108E-03 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 8,175E-04 6,089E-03 ! regulation of muscle hypertrophy GO:0014743 12 8 1,000 8,175E-04 6,07E-03 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 1,000 8,175E-04 6,052E-03 ! positive regulation of insulin secretion GO:0032024 15 8 1,000 8,175E-04 6,033E-03 ! regulation of vascular permeability GO:0043114 12 8 1,000 8,175E-04 6,015E-03 ! blastocyst growth GO:0001832 19 8 1,000 8,175E-04 5,996E-03 ! B cell receptor signaling pathway GO:0050853 16 8 1,000 8,175E-04 5,978E-03 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 1,000 8,175E-04 5,96E-03 ! positive regulation of ligase activity GO:0051351 124 77 3,000 8,612E-04 6,26E-03 ! protein oligomerization GO:0051259 139 78 3,000 9,04E-04 6,551E-03 ! negative regulation of DNA metabolic process GO:0051053 61 35 2,000 9,291E-04 6,713E-03 ! regulation of peptidase activity GO:0052547 134 79 3,000 9,481E-04 6,83E-03 ! cell junction organization GO:0034330 86 36 2,000 1,01E-03 7,25E-03 ! embryonic organ development GO:0048568 57 36 2,000 1,01E-03 7,229E-03 ! negative regulation of cell activation GO:0050866 65 36 2,000 1,01E-03 7,207E-03 ! T cell activation GO:0042110 168 81 3,000 1,041E-03 7,41E-03 ! cell-substrate adhesion GO:0031589 171 81 3,000 1,041E-03 7,389E-03 ! regulation of developmental growth GO:0048638 15 9 1,000 1,047E-03 7,411E-03 ! DNA synthesis during DNA repair GO:0000731 14 9 1,000 1,047E-03 7,389E-03 ! T cell selection GO:0045058 23 9 1,000 1,047E-03 7,367E-03 ! receptor clustering GO:0043113 18 9 1,000 1,047E-03 7,346E-03 ! retinol metabolic process GO:0042572 18 9 1,000 1,047E-03 7,325E-03 ! protein heterooligomerization GO:0051291 16 9 1,000 1,047E-03 7,303E-03 ! gas homeostasis GO:0033483 16 9 1,000 1,047E-03 7,282E-03 ! postreplication repair GO:0006301 22 9 1,000 1,047E-03 7,261E-03 ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 1,000 1,047E-03 7,24E-03 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 1,000 1,047E-03 7,22E-03 GO:0002820|negative regulation of adaptive immune response, ! regulation of muscle adaptation GO:0043502 14 9 1,000 1,047E-03 7,199E-03 ! negative regulation of DNA binding GO:0043392 68 37 2,000 1,094E-03 7,5E-03 ! glycogen metabolic process GO:0005977 61 37 2,000 1,094E-03 7,479E-03 ! positive regulation of DNA metabolic process GO:0051054 72 38 2,000 1,183E-03 8,065E-03 ! development of primary female sexual characteristics GO:0046545 67 38 2,000 1,183E-03 8,042E-03 GO:0046660|female sex differentiation, ! embryonic epithelial tube formation GO:0001838 72 38 2,000 1,183E-03 8,019E-03 ! positive regulation of leukocyte proliferation GO:0070665 62 38 2,000 1,183E-03 7,997E-03 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! glucan metabolic process GO:0044042 62 38 2,000 1,183E-03 7,974E-03 GO:0006073|cellular glucan metabolic process, ! mammary gland development GO:0030879 86 39 2,000 1,277E-03 8,58E-03 ! learning GO:0007612 77 39 2,000 1,277E-03 8,556E-03 ! mitochondrion organization GO:0007005 148 86 3,000 1,301E-03 8,695E-03 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 1,000 1,304E-03 8,693E-03 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 1,000 1,304E-03 8,669E-03 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 1,000 1,304E-03 8,645E-03 ! lung alveolus development GO:0048286 26 10 1,000 1,304E-03 8,622E-03 ! negative regulation of striated muscle development GO:0045843 19 10 1,000 1,304E-03 8,598E-03 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 1,000 1,304E-03 8,574E-03 ! glucan biosynthetic process GO:0009250 14 10 1,000 1,304E-03 8,551E-03 GO:0005978|glycogen biosynthetic process, ! multicellular organism growth GO:0035264 18 10 1,000 1,304E-03 8,528E-03 ! regulation of bone resorption GO:0045124 25 10 1,000 1,304E-03 8,505E-03 ! regulation of B cell differentiation GO:0045577 19 10 1,000 1,304E-03 8,482E-03 ! positive regulation of leukocyte migration GO:0002687 25 10 1,000 1,304E-03 8,459E-03 ! oocyte development GO:0048599 17 10 1,000 1,304E-03 8,436E-03 ! negative regulation of immune effector process GO:0002698 20 10 1,000 1,304E-03 8,414E-03 ! localization within membrane GO:0051668 20 10 1,000 1,304E-03 8,391E-03 ! negative regulation of binding GO:0051100 72 40 2,000 1,375E-03 8,82E-03 ! mesenchymal cell development GO:0014031 87 40 2,000 1,375E-03 8,797E-03 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! positive regulation of protein modification process GO:0031401 136 88 3,000 1,417E-03 9,04E-03 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 2,000 1,477E-03 9,403E-03 ! regulation of cell cycle process GO:0010564 149 90 3,000 1,539E-03 9,771E-03 ! positive regulation of transcription factor activity GO:0051091 62 42 2,000 1,585E-03 0,01003284 GO:0090047|positive regulation of transcription regulator activity, ! regulation of myeloid cell differentiation GO:0045637 98 42 2,000 1,585E-03 0,01000651 ! negative regulation of muscle development GO:0048635 20 11 1,000 1,588E-03 0,0100048 ! T cell proliferation GO:0042098 26 11 1,000 1,588E-03 9,979E-03 ! regulation of intracellular pH GO:0051453 19 11 1,000 1,588E-03 9,953E-03 ! positive regulation of peptide secretion GO:0002793 22 11 1,000 1,588E-03 9,927E-03 ! positive regulation of T cell mediated immunity GO:0002711 24 11 1,000 1,588E-03 9,901E-03 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 1,000 1,588E-03 9,876E-03 ! regulation of isotype switching GO:0045191 22 11 1,000 1,588E-03 9,85E-03 ! regulation of leukocyte migration GO:0002685 26 11 1,000 1,588E-03 9,825E-03 ! nitric oxide mediated signal transduction GO:0007263 23 11 1,000 1,588E-03 9,8E-03 ! oocyte differentiation GO:0009994 18 11 1,000 1,588E-03 9,775E-03 ! T cell receptor signaling pathway GO:0050852 23 11 1,000 1,588E-03 9,75E-03 ! regulation of embryonic development GO:0045995 27 11 1,000 1,588E-03 9,725E-03 ! energy reserve metabolic process GO:0006112 74 43 2,000 1,697E-03 0,01036051 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 3,000 1,737E-03 0,01057741 GO:0010498|proteasomal protein catabolic process, ! regulation of T cell activation GO:0050863 158 94 3,000 1,806E-03 0,01097316 ! double-strand break repair GO:0006302 81 44 2,000 1,813E-03 0,0109905 ! developmental growth GO:0048589 82 44 2,000 1,813E-03 0,01096289 ! virus-host interaction GO:0019048 29 12 1,000 1,899E-03 0,01145293 ! cartilage condensation GO:0001502 20 12 1,000 1,899E-03 0,01142429 ! dopamine receptor signaling pathway GO:0007212 28 12 1,000 1,899E-03 0,0113958 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 1,000 1,899E-03 0,01136746 ! protein homotetramerization GO:0051289 21 12 1,000 1,899E-03 0,01133925 ! autonomic nervous system development GO:0048483 24 12 1,000 1,899E-03 0,01131118 ! T cell homeostasis GO:0043029 25 12 1,000 1,899E-03 0,01128325 ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 1,000 1,899E-03 0,01125546 ! leukocyte migration GO:0050900 68 45 2,000 1,935E-03 0,01144034 ! leukocyte differentiation GO:0002521 202 96 3,000 1,951E-03 0,01150438 ! positive regulation of DNA binding GO:0043388 73 47 2,000 2,194E-03 0,01290537 ! vascular process in circulatory system GO:0003018 80 47 2,000 2,194E-03 0,01287389 ! regulation of chemokine production GO:0032642 18 13 1,000 2,237E-03 0,01309287 ! double-strand break repair via homologous recombination GO:0000724 19 13 1,000 2,237E-03 0,0130611 GO:0000725|recombinational repair, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 1,000 2,237E-03 0,01302947 ! regulation of DNA repair GO:0006282 21 13 1,000 2,237E-03 0,012998 ! regulation of cellular pH GO:0030641 22 13 1,000 2,237E-03 0,01296668 ! regulation of mRNA stability GO:0043488 31 13 1,000 2,237E-03 0,01293551 ! cytoplasmic sequestering of protein GO:0051220 24 13 1,000 2,237E-03 0,01290449 ! morphogenesis of embryonic epithelium GO:0016331 91 48 2,000 2,331E-03 0,01341559 ! activation of caspase activity GO:0006919 84 48 2,000 2,331E-03 0,01338357 ! induction of apoptosis by extracellular signals GO:0008624 89 49 2,000 2,473E-03 0,01416573 ! retina development in camera-type eye GO:0060041 27 14 1,000 2,6E-03 0,01485864 ! actin cytoskeleton reorganization GO:0031532 33 14 1,000 2,6E-03 0,01482343 ! bone mineralization GO:0030282 17 14 1,000 2,6E-03 0,01478838 ! negative regulation of protein import into nucleus GO:0042308 30 14 1,000 2,6E-03 0,01475351 ! T cell differentiation in the thymus GO:0033077 31 14 1,000 2,6E-03 0,01471879 ! regulation of RNA stability GO:0043487 32 14 1,000 2,6E-03 0,01468424 ! release of cytochrome c from mitochondria GO:0001836 30 14 1,000 2,6E-03 0,01464985 ! histone modification GO:0016570 91 50 2,000 2,62E-03 0,01472926 ! positive regulation of binding GO:0051099 78 51 2,000 2,773E-03 0,01555111 ! cellular amino acid biosynthetic process GO:0008652 75 51 2,000 2,773E-03 0,01551494 ! epithelial tube morphogenesis GO:0060562 98 51 2,000 2,773E-03 0,01547894 ! regulation of angiogenesis GO:0045765 114 52 2,000 2,931E-03 0,01632328 ! regulation of muscle contraction GO:0006937 81 52 2,000 2,931E-03 0,01628558 ! positive regulation of growth GO:0045927 90 52 2,000 2,931E-03 0,01624806 ! covalent chromatin modification GO:0016569 101 52 2,000 2,931E-03 0,0162107 ! negative regulation of bone remodeling GO:0046851 33 15 1,000 2,989E-03 0,01649532 ! regulation of transmembrane transporter activity GO:0022898 27 15 1,000 2,989E-03 0,01645757 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 1,000 2,989E-03 0,01642 ! G1/S transition checkpoint GO:0031575 40 15 1,000 2,989E-03 0,01638259 ! regulation of T cell mediated immunity GO:0002709 33 15 1,000 2,989E-03 0,01634536 ! mRNA splice site selection GO:0006376 38 15 1,000 2,989E-03 0,0163083 ! muscle maintenance GO:0046716 26 15 1,000 2,989E-03 0,0162714 ! lymphocyte homeostasis GO:0002260 30 15 1,000 2,989E-03 0,01623467 ! epithelial to mesenchymal transition GO:0001837 28 15 1,000 2,989E-03 0,0161981 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 1,000 2,989E-03 0,0161617 ! cell maturation GO:0048469 100 53 2,000 3,094E-03 0,01669275 ! embryonic forelimb morphogenesis GO:0035115 28 16 1,000 3,404E-03 0,0183219 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 1,000 3,404E-03 0,018281 ! activation of MAPKK activity GO:0000186 35 16 1,000 3,404E-03 0,01824029 ! negative regulation of immune response GO:0050777 35 16 1,000 3,404E-03 0,01819975 ! negative regulation of inflammatory response GO:0050728 22 16 1,000 3,404E-03 0,0181594 ! negative regulation of tissue remodeling GO:0034104 36 16 1,000 3,404E-03 0,01811922 ! biomineral formation GO:0031214 20 16 1,000 3,404E-03 0,01807922 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 1,000 3,404E-03 0,0180394 ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 3,404E-03 0,01799975 ! defense response to virus GO:0051607 37 16 1,000 3,404E-03 0,01796028 ! cellular polysaccharide metabolic process GO:0044264 86 55 2,000 3,438E-03 0,01809933 ! nucleotide-excision repair GO:0006289 83 56 2,000 3,618E-03 0,01900608 ! positive regulation of cell killing GO:0031343 32 17 1,000 3,844E-03 0,02014942 ! signal complex assembly GO:0007172 41 17 1,000 3,844E-03 0,02010561 ! heart looping GO:0001947 30 17 1,000 3,844E-03 0,020062 ! regulation of survival gene product expression GO:0045884 33 17 1,000 3,844E-03 0,02001858 ! negative regulation of protein catabolic process GO:0042177 40 17 1,000 3,844E-03 0,01997534 ! genitalia development GO:0048806 30 17 1,000 3,844E-03 0,01993229 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 1,000 3,844E-03 0,01988942 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 1,000 3,844E-03 0,01984674 GO:0002712|regulation of B cell mediated immunity, ! negative regulation of homeostatic process GO:0032845 33 17 1,000 3,844E-03 0,01980425 ! microspike assembly GO:0030035 36 17 1,000 3,844E-03 0,01976193 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 1,000 3,844E-03 0,01971979 ! neuron maturation GO:0042551 42 18 1,000 4,309E-03 0,0220582 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 4,309E-03 0,02201137 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 1,000 4,309E-03 0,02196473 GO:0050886|endocrine process, ! centrosome cycle GO:0007098 25 18 1,000 4,309E-03 0,0219183 ! positive regulation of proteolysis GO:0045862 31 18 1,000 4,309E-03 0,02187205 ! response to retinoic acid GO:0032526 26 18 1,000 4,309E-03 0,02182601 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 1,000 4,309E-03 0,02178015 ! vitamin transport GO:0051180 27 18 1,000 4,309E-03 0,02173449 ! regulation of heart contraction GO:0008016 110 60 2,000 4,396E-03 0,02212534 ! kidney development GO:0001822 122 60 2,000 4,396E-03 0,02207915 ! negative regulation of defense response GO:0031348 25 19 1,000 4,799E-03 0,02405317 ! positive regulation of angiogenesis GO:0045766 44 19 1,000 4,799E-03 0,02400316 ! positive regulation of hormone secretion GO:0046887 32 19 1,000 4,799E-03 0,02395336 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 1,000 4,799E-03 0,02390377 ! lipid phosphorylation GO:0046834 35 19 1,000 4,799E-03 0,02385438 ! forelimb morphogenesis GO:0035136 32 19 1,000 4,799E-03 0,0238052 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 1,000 4,799E-03 0,02375621 ! response to vitamin A GO:0033189 27 19 1,000 4,799E-03 0,02370743 ! neuromuscular junction development GO:0007528 34 19 1,000 4,799E-03 0,02365885 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 1,000 4,799E-03 0,02361047 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 1,000 4,799E-03 0,02356229 ! embryonic organ morphogenesis GO:0048562 26 19 1,000 4,799E-03 0,0235143 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 1,000 5,313E-03 0,0259805 ! response to vitamin GO:0033273 31 20 1,000 5,313E-03 0,0259278 ! retinoid metabolic process GO:0001523 32 20 1,000 5,313E-03 0,02587531 GO:0016101|diterpenoid metabolic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 1,000 5,313E-03 0,02582304 ! camera-type eye morphogenesis GO:0048593 42 20 1,000 5,313E-03 0,02577098 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 1,000 5,313E-03 0,02571912 ! germ cell development GO:0007281 118 65 2,000 5,5E-03 0,02657314 ! cell projection assembly GO:0030031 120 66 2,000 5,739E-03 0,0276724 ! regulation of cell killing GO:0031341 42 21 1,000 5,851E-03 0,02815468 ! hindlimb morphogenesis GO:0035137 43 21 1,000 5,851E-03 0,02809848 ! cell structure disassembly during apoptosis GO:0006921 30 21 1,000 5,851E-03 0,02804251 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 1,000 5,851E-03 0,02798675 ! regulation of vasoconstriction GO:0019229 39 21 1,000 5,851E-03 0,02793123 ! oogenesis GO:0048477 36 21 1,000 5,851E-03 0,02787592 ! vitamin A metabolic process GO:0006776 33 21 1,000 5,851E-03 0,02782083 ! terpenoid metabolic process GO:0006721 37 21 1,000 5,851E-03 0,02776595 ! gut development GO:0048565 39 21 1,000 5,851E-03 0,02771129 ! activation of MAPK activity GO:0000187 115 67 2,000 5,984E-03 0,02828763 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 2,000 5,984E-03 0,02823216 ! viral reproduction GO:0016032 134 68 2,000 6,236E-03 0,02936038 ! glutamate signaling pathway GO:0007215 41 22 1,000 6,413E-03 0,03013604 ! apoptotic nuclear changes GO:0030262 32 22 1,000 6,413E-03 0,0300773 ! ureteric bud development GO:0001657 43 22 1,000 6,413E-03 0,03001878 ! renal system process GO:0003014 41 22 1,000 6,413E-03 0,02996049 ! positive regulation of adaptive immune response GO:0002821 39 22 1,000 6,413E-03 0,02990243 ! protein stabilization GO:0050821 39 22 1,000 6,413E-03 0,02984459 ! cell cycle checkpoint GO:0000075 137 69 2,000 6,493E-03 0,03015998 ! positive regulation of DNA replication GO:0045740 43 23 1,000 6,999E-03 0,03244449 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 6,999E-03 0,0323821 ! gluconeogenesis GO:0006094 33 23 1,000 6,999E-03 0,03231994 ! leukocyte adhesion GO:0007159 50 23 1,000 6,999E-03 0,03225803 ! regulation of DNA recombination GO:0000018 48 23 1,000 6,999E-03 0,03219635 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 1,000 6,999E-03 0,03213491 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 1,000 6,999E-03 0,0320737 ! sex determination GO:0007530 47 23 1,000 6,999E-03 0,03201272 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 1,000 6,999E-03 0,03195198 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 1,000 6,999E-03 0,03189146 ! negative regulation of catabolic process GO:0009895 50 23 1,000 6,999E-03 0,03183117 ! reproductive structure development GO:0048608 113 71 2,000 7,027E-03 0,03190106 ! regulation of immune effector process GO:0002697 137 71 2,000 7,027E-03 0,03184098 ! axon guidance GO:0007411 139 73 2,000 7,587E-03 0,03431049 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 1,000 7,608E-03 0,03434108 ! regulation of transmembrane transport GO:0034762 38 24 1,000 7,608E-03 0,03427677 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 1,000 7,608E-03 0,03421271 ! digestive system process GO:0022600 39 24 1,000 7,608E-03 0,03414888 ! regulation of alpha-beta T cell activation GO:0046634 42 24 1,000 7,608E-03 0,03408528 ! lymphocyte proliferation GO:0046651 48 24 1,000 7,608E-03 0,03402193 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 1,000 7,608E-03 0,03395881 GO:0002708|positive regulation of lymphocyte mediated immunity, ! leukocyte homeostasis GO:0001776 44 24 1,000 7,608E-03 0,03389592 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 1,000 8,24E-03 0,03664385 ! myelination GO:0042552 45 25 1,000 8,24E-03 0,03657624 ! protein amino acid alkylation GO:0008213 53 25 1,000 8,24E-03 0,03650888 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 1,000 8,24E-03 0,03644177 ! receptor metabolic process GO:0043112 46 25 1,000 8,24E-03 0,03637491 ! negative regulation of cell development GO:0010721 73 25 1,000 8,24E-03 0,03630829 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 1,000 8,24E-03 0,03624191 ! interaction with host GO:0051701 62 25 1,000 8,24E-03 0,03617577 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 1,000 8,24E-03 0,03610988 ! somitogenesis GO:0001756 43 25 1,000 8,24E-03 0,03604423 ! immunoglobulin production GO:0002377 55 25 1,000 8,24E-03 0,03597881 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 36 25 1,000 8,24E-03 0,03591363 ! neural tube closure GO:0001843 49 25 1,000 8,24E-03 0,03584869 GO:0060606|tube closure, ! development of primary sexual characteristics GO:0045137 124 76 2,000 8,474E-03 0,03680013 ! positive regulation of lymphocyte activation GO:0051251 127 77 2,000 8,782E-03 0,03807166 ! pyruvate metabolic process GO:0006090 38 26 1,000 8,894E-03 0,03848854 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 1,000 8,894E-03 0,03841944 ! molting cycle process GO:0022404 50 26 1,000 8,894E-03 0,03835058 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 1,000 8,894E-03 0,03828198 ! microtubule organizing center organization GO:0031023 39 26 1,000 8,894E-03 0,03821362 GO:0051297|centrosome organization, ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 1,000 8,894E-03 0,0381455 ! positive regulation of MAPKKK cascade GO:0043410 47 26 1,000 8,894E-03 0,03807763 ! blastocyst development GO:0001824 49 26 1,000 8,894E-03 0,03800999 ! leukocyte proliferation GO:0070661 52 26 1,000 8,894E-03 0,0379426 GO:0032943|mononuclear cell proliferation, ! spliceosomal snRNP biogenesis GO:0000387 36 27 1,000 9,572E-03 0,04075941 ! mitochondrial membrane organization GO:0007006 57 27 1,000 9,572E-03 0,04068739 ! primary neural tube formation GO:0014020 51 27 1,000 9,572E-03 0,04061563 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 1,000 9,572E-03 0,04054413 ! base-excision repair GO:0006284 41 27 1,000 9,572E-03 0,04047287 ! fat-soluble vitamin metabolic process GO:0006775 40 27 1,000 9,572E-03 0,04040187 ! protein import into nucleus GO:0006606 158 80 2,000 9,747E-03 0,04107126 ! nuclear import GO:0051170 161 81 2,000 0,01008202 0,04240794 ! regulation of systemic arterial blood pressure GO:0003073 54 28 1,000 0,01027099 0,04312741 ! positive regulation of T cell differentiation GO:0045582 42 28 1,000 0,01027099 0,04305228 ! peptidyl-tyrosine modification GO:0018212 50 28 1,000 0,01027099 0,04297741 ! response to nutrient GO:0007584 125 82 2,000 0,0104235 0,04353981 ! regulation of pH GO:0006885 43 29 1,000 0,01099245 0,04583679 ! cellular iron ion homeostasis GO:0006879 51 29 1,000 0,01099245 0,04575749 ! regulation of peptide secretion GO:0002791 47 29 1,000 0,01099245 0,04567846 ! immune response-activating signal transduction GO:0002757 47 29 1,000 0,01099245 0,04559971 GO:0002764|immune response-regulating signal transduction, ! response to organic cyclic substance GO:0014070 55 29 1,000 0,01099245 0,04552122 ! positive regulation of cell activation GO:0050867 145 85 2,000 0,01148791 0,04749125 GO:0002696|positive regulation of leukocyte activation, ! positive regulation of multicellular organism growth GO:0040018 51 30 1,000 0,01173562 0,04843208 ! ensheathment of neurons GO:0007272 57 30 1,000 0,01173562 0,04834915 GO:0008366|axon ensheathment, ! eye morphogenesis GO:0048592 60 30 1,000 0,01173562 0,0482665 ! response to heat GO:0009408 50 30 1,000 0,01173562 0,04818414 ! amine biosynthetic process GO:0009309 138 86 2,000 0,01185611 0,04859593 ! tube morphogenesis GO:0035239 176 86 2,000 0,01185611 0,04851328 ! protein localization in nucleus GO:0034504 176 87 2,000 0,01223105 0,04996249 ! collagen metabolic process GO:0032963 45 31 1,000 0,01250026 0,05097562 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 1,000 0,01250026 0,05088936 ! positive regulation of T cell proliferation GO:0042102 52 31 1,000 0,01250026 0,0508034 ! iron ion homeostasis GO:0055072 54 31 1,000 0,01250026 0,05071773 ! positive regulation of immune effector process GO:0002699 67 31 1,000 0,01250026 0,05063235 ! gland development GO:0048732 206 88 2,000 0,01261274 0,0510021 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 1,000 0,0132861 0,05363482 ! negative regulation of response to external stimulus GO:0032102 47 32 1,000 0,0132861 0,05354497 ! metanephros development GO:0001656 74 32 1,000 0,0132861 0,05345543 ! regulation of ARF GTPase activity GO:0032312 65 32 1,000 0,0132861 0,05336619 ! hexose biosynthetic process GO:0019319 48 32 1,000 0,0132861 0,05327725 ! peripheral nervous system development GO:0007422 64 32 1,000 0,0132861 0,0531886 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 1,000 0,0132861 0,05310025 ! sex differentiation GO:0007548 145 90 2,000 0,01339644 0,05345247 ! DNA damage checkpoint GO:0000077 71 33 1,000 0,01409289 0,05613825 ! carbohydrate biosynthetic process GO:0016051 141 93 2,000 0,01462305 0,0581538 ! negative regulation of multicellular organismal process GO:0051241 166 93 2,000 0,01462305 0,05805784 ! positive regulation of endocytosis GO:0045807 50 34 1,000 0,01492039 0,05914081 ! regulation of striated muscle tissue development GO:0016202 69 34 1,000 0,01492039 0,05904354 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 1,000 0,01492039 0,05894658 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 1,000 0,01492039 0,05884995 ! regulation of muscle development GO:0048634 70 35 1,000 0,01576835 0,06209272 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 1,000 0,01576835 0,06199127 ! regulation of synaptic plasticity GO:0048167 64 35 1,000 0,01576835 0,06189014 ! female gonad development GO:0008585 58 35 1,000 0,01576835 0,06178934 ! negative regulation of hydrolase activity GO:0051346 62 35 1,000 0,01576835 0,06168887 ! calcium-mediated signaling GO:0019722 62 35 1,000 0,01576835 0,06158872 ! neural tube formation GO:0001841 67 35 1,000 0,01576835 0,06148891 ! protein ubiquitination GO:0016567 217 97 2,000 0,01635438 0,06367094 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 1,000 0,01663652 0,06466473 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! maintenance of protein location in cell GO:0032507 86 36 1,000 0,01663652 0,06456043 ! DNA integrity checkpoint GO:0031570 75 36 1,000 0,01663652 0,06445647 ! regulation of proteolysis GO:0030162 72 36 1,000 0,01663652 0,06435284 ! monosaccharide biosynthetic process GO:0046364 52 36 1,000 0,01663652 0,06424954 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 2,000 0,01726133 0,06655571 ! skeletal muscle tissue development GO:0007519 186 99 2,000 0,01726133 0,06644922 GO:0060538|skeletal muscle organ development, ! monovalent inorganic cation homeostasis GO:0055067 58 37 1,000 0,01752465 0,06735513 ! mitotic cell cycle checkpoint GO:0007093 76 38 1,000 0,01843251 0,07073145 ! nucleus organization GO:0006997 67 38 1,000 0,01843251 0,07061882 ! isoprenoid metabolic process GO:0006720 66 38 1,000 0,01843251 0,07050655 ! segmentation GO:0035282 67 39 1,000 0,01935985 0,07393619 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 1,000 0,01935985 0,07381902 ! regulation of action potential in neuron GO:0019228 73 39 1,000 0,01935985 0,07370222 ! response to xenobiotic stimulus GO:0009410 57 39 1,000 0,01935985 0,07358578 ! regulation of hormone secretion GO:0046883 62 40 1,000 0,02030644 0,07706197 ! multicellular organismal metabolic process GO:0044236 57 40 1,000 0,02030644 0,07694061 ! maintenance of protein location GO:0045185 91 40 1,000 0,02030644 0,07681964 ! cytokinesis GO:0000910 72 40 1,000 0,02030644 0,07669904 ! female gamete generation GO:0007292 61 41 1,000 0,02127204 0,08022025 ! regulation of tube size GO:0035150 71 42 1,000 0,02225641 0,08380113 GO:0050880|regulation of blood vessel size, ! alcohol biosynthetic process GO:0046165 59 42 1,000 0,02225641 0,08367019 ! regulation of leukocyte mediated immunity GO:0002703 79 42 1,000 0,02225641 0,08353966 ! neuron migration GO:0001764 79 42 1,000 0,02225641 0,08340953 ! regulation of protein secretion GO:0050708 71 42 1,000 0,02225641 0,08327981 ! glucose transport GO:0015758 65 43 1,000 0,02325933 0,08689742 ! neural tube development GO:0021915 77 43 1,000 0,02325933 0,08676269 ! hexose transport GO:0008645 67 44 1,000 0,02428056 0,09043192 GO:0015749|monosaccharide transport, ! biopolymer methylation GO:0043414 84 44 1,000 0,02428056 0,09029215 ! B cell differentiation GO:0030183 107 44 1,000 0,02428056 0,09015281 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 1,000 0,02428056 0,0900139 ! maintenance of location in cell GO:0051651 97 44 1,000 0,02428056 0,08987541 ! polysaccharide biosynthetic process GO:0000271 70 45 1,000 0,02531987 0,09357852 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,02709643 0,09999082 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,02709643 0,0998377 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,02709643 0,09968504 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,02709643 0,09953285 ! neuron fate determination GO:0048664 7 5 0,000 0,02709643 0,09938112 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02709643 0,09922986 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,02709643 0,09907905 ! polyol transport GO:0015791 12 5 0,000 0,02709643 0,0989287 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,02709643 0,09877881 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,02709643 0,09862937 ! response to superoxide GO:0000303 10 5 0,000 0,02709643 0,09848039 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,02709643 0,09833185 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,02709643 0,09818376 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,02709643 0,09803611 ! female meiosis GO:0007143 7 5 0,000 0,02709643 0,09788891 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,02709643 0,09774215 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,02709643 0,09759583 ! cobalt ion transport GO:0006824 11 5 0,000 0,02709643 0,09744995 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,02709643 0,0973045 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,02709643 0,09715949 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,02709643 0,0970149 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,02709643 0,09687075 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,02709643 0,09672703 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,02709643 0,09658373 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,02709643 0,09644085 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02709643 0,0962984 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,02709643 0,09615637 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,02709643 0,09601475 ! negative chemotaxis GO:0050919 14 5 0,000 0,02709643 0,09587355 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,02709643 0,09573277 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,02709643 0,0955924 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,02709643 0,09545244 ! behavioral response to pain GO:0048266 9 5 0,000 0,02709643 0,09531289 ! clathrin coat assembly GO:0048268 14 5 0,000 0,02709643 0,09517375 ! Notch receptor processing GO:0007220 8 5 0,000 0,02709643 0,09503501 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02709643 0,09489667 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! micturition GO:0060073 9 5 0,000 0,02709643 0,09475874 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,02709643 0,09462121 ! copulation GO:0007620 9 5 0,000 0,02709643 0,09448408 ! glial cell fate commitment GO:0021781 13 5 0,000 0,02709643 0,09434735 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,02709643 0,09421101 ! spermidine metabolic process GO:0008216 7 5 0,000 0,02709643 0,09407506 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,02709643 0,0939395 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,02709643 0,09380434 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,02709643 0,09366956 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,02709643 0,09353517 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,02709643 0,09340117 ! grooming behavior GO:0007625 6 5 0,000 0,02709643 0,09326755 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,02709643 0,09313431 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,02709643 0,09300145 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02709643 0,09286897 ! response to protozoan GO:0001562 10 5 0,000 0,02709643 0,09273686 ! lymph vessel development GO:0001945 10 5 0,000 0,02709643 0,09260514 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,02709643 0,09247378 ! endochondral ossification GO:0001958 16 5 0,000 0,02709643 0,0923428 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,02709643 0,09221219 ! parathyroid gland development GO:0060017 13 5 0,000 0,02709643 0,09208194 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,02709643 0,09195207 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,02709643 0,09182256 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,02709643 0,09169341 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,02709643 0,09156463 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,02709643 0,09143621 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,02709643 0,09130815 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,02709643 0,09118044 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,02709643 0,09105309 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,02709643 0,0909261 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,02709643 0,09079946 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,02709643 0,09067318 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,02709643 0,09054724 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,02709643 0,09042166 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,02709643 0,09029642 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,02709643 0,09017153 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,02709643 0,09004698 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 0,02709643 0,08992278 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,02709643 0,08979892 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,02709643 0,0896754 ! histidine catabolic process GO:0006548 6 5 0,000 0,02709643 0,08955222 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,02709643 0,08942938 ! valine metabolic process GO:0006573 10 5 0,000 0,02709643 0,08930687 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,02709643 0,0891847 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,02709643 0,08906286 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,02709643 0,08894136 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,02709643 0,08882018 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,02709643 0,08869934 ! polyol catabolic process GO:0046174 7 5 0,000 0,02709643 0,08857883 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,02709643 0,08845864 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,02709643 0,08833877 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,02709643 0,08821924 ! muscle cell migration GO:0014812 8 5 0,000 0,02709643 0,08810002 ! mitochondrial fission GO:0000266 8 5 0,000 0,02709643 0,08798113 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,02709643 0,08786255 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,02709643 0,0877443 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,02709643 0,08762637 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,02709643 0,08750875 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,02709643 0,08739144 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,02709643 0,08727445 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,02709643 0,08715777 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,02709643 0,08704141 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,02709643 0,08692535 ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,02709643 0,08680961 GO:0032881|regulation of polysaccharide metabolic process, ! paraxial mesoderm development GO:0048339 14 5 0,000 0,02709643 0,08669417 ! forebrain neuron development GO:0021884 13 5 0,000 0,02709643 0,08657904 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,02709643 0,08646421 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,02709643 0,08634969 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02709643 0,08623547 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,02709643 0,08612155 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,02709643 0,08600794 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02709643 0,08589462 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,02709643 0,0857816 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,02709643 0,08566888 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,02709643 0,08555645 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,02709643 0,08544432 ! basic amino acid transport GO:0015802 11 5 0,000 0,02709643 0,08533248 ! depyrimidination GO:0045008 10 5 0,000 0,02709643 0,08522094 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,02709643 0,08510968 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02709643 0,08499872 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,02709643 0,08488804 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,02709643 0,08477765 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 0,02709643 0,08466755 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,02709643 0,08455774 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02709643 0,08444821 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,02709643 0,08433896 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,02709643 0,08422999 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,02709643 0,08412131 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,02709643 0,08401291 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,02709643 0,08390478 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02709643 0,08379694 ! response to arsenic GO:0046685 10 5 0,000 0,02709643 0,08368937 ! mast cell degranulation GO:0043303 7 5 0,000 0,02709643 0,08358207 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,02709643 0,08347505 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,02709643 0,08336831 ! response to cadmium ion GO:0046686 7 5 0,000 0,02709643 0,08326183 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,02709643 0,08315563 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,02709643 0,0830497 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,02709643 0,08294404 ! decidualization GO:0046697 11 5 0,000 0,02709643 0,08283865 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,02709643 0,08273352 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,02709643 0,08262866 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,02709643 0,08252407 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,02709643 0,08241974 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,02709643 0,08231568 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,02709643 0,08221187 ! neural tube patterning GO:0021532 7 5 0,000 0,02709643 0,08210833 ! embryonic cleavage GO:0040016 6 5 0,000 0,02709643 0,08200505 ! peroxisome fission GO:0016559 5 5 0,000 0,02709643 0,08190203 ! histone demethylation GO:0016577 10 5 0,000 0,02709643 0,08179927 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,02709643 0,08169676 ! mitotic recombination GO:0006312 9 5 0,000 0,02709643 0,08159451 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,02709643 0,08149252 ! metaphase plate congression GO:0051310 7 5 0,000 0,02709643 0,08139078 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02709643 0,0812893 GO:0032374|regulation of cholesterol transport, ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,02709643 0,08118806 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,02709643 0,08108708 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,02709643 0,08098635 ! muscle cell proliferation GO:0033002 11 5 0,000 0,02709643 0,08088588 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,02709643 0,08078565 ! plasminogen activation GO:0031639 5 5 0,000 0,02709643 0,08068566 ! B cell homeostasis GO:0001782 13 5 0,000 0,02709643 0,08058593 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,02709643 0,08048644 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,02709643 0,0803872 ! metaphase GO:0051323 8 5 0,000 0,02709643 0,0802882 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,02709643 0,08018944 ! cellular response to nutrient GO:0031670 8 5 0,000 0,02709643 0,08009093 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,02709643 0,07999266 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,02709643 0,07989463 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,02709643 0,07979684 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,02709643 0,07969929 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,02709643 0,07960197 ! response to redox state GO:0051775 5 5 0,000 0,02709643 0,0795049 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,02709643 0,07940806 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,02709643 0,07931145 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,02709643 0,07921509 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,02709643 0,07911895 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02709643 0,07902305 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,02709643 0,07892738 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02709643 0,07883194 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,02709643 0,07873673 ! striatum development GO:0021756 9 5 0,000 0,02709643 0,07864176 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,02709643 0,07854701 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,02709643 0,07845249 ! glial cell migration GO:0008347 11 5 0,000 0,02709643 0,07835819 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,02709643 0,07826412 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,02709643 0,07817028 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,02709643 0,07807667 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,02709643 0,07798327 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,02709643 0,0778901 ! neuroprotection GO:0043526 6 5 0,000 0,02709643 0,07779715 ! neural plate development GO:0001840 8 5 0,000 0,02709643 0,07770443 ! regulation of sensory perception GO:0051931 7 5 0,000 0,02709643 0,07761192 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,02709643 0,07751964 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,02709643 0,07742757 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,02709643 0,07733572 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,02709643 0,07724409 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,02709643 0,07715268 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,02709643 0,07706148 ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,02709643 0,0769705 ! spindle assembly GO:0051225 6 5 0,000 0,02709643 0,07687974 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,02709643 0,07678918 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,02709643 0,07669884 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,02709643 0,07660871 ! drug metabolic process GO:0017144 6 5 0,000 0,02709643 0,0765188 ! phospholipid scrambling GO:0017121 8 5 0,000 0,02709643 0,07642909 ! organ regeneration GO:0031100 7 5 0,000 0,02709643 0,0763396 ! carnitine metabolic process GO:0009437 7 5 0,000 0,02709643 0,07625031 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,02709643 0,07616123 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,02709643 0,07607236 ! endosome transport GO:0016197 108 47 1,000 0,02745186 0,07698039 ! regulation of adaptive immune response GO:0002819 84 47 1,000 0,02745186 0,07689077 ! methylation GO:0032259 90 47 1,000 0,02745186 0,07680137 ! protein homooligomerization GO:0051260 76 47 1,000 0,02745186 0,07671216 ! mitochondrial transport GO:0006839 82 48 1,000 0,02854408 0,07967177 ! cellular component disassembly GO:0022411 86 48 1,000 0,02854408 0,07957945 ! regulation of ARF protein signal transduction GO:0032012 102 48 1,000 0,02854408 0,07948734 ! regulation of action potential GO:0001508 95 49 1,000 0,0296535 0,08248129 ! response to temperature stimulus GO:0009266 76 49 1,000 0,0296535 0,08238605 ! DNA-dependent DNA replication GO:0006261 74 49 1,000 0,0296535 0,08229102 ! response to estrogen stimulus GO:0043627 93 51 1,000 0,03192303 0,08848712 ! embryonic skeletal system development GO:0048706 85 51 1,000 0,03192303 0,08838529 ! chromatin remodeling GO:0006338 109 51 1,000 0,03192303 0,0882837 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 1,000 0,03192303 0,08818234 ! regulation of cell shape GO:0008360 125 51 1,000 0,03192303 0,08808121 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,0324275 0,08937063 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,0324275 0,08926838 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,0324275 0,08916636 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,0324275 0,08906457 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,0324275 0,08896301 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,0324275 0,08886169 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,0324275 0,08876059 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,0324275 0,08865973 ! sleep GO:0030431 13 6 0,000 0,0324275 0,0885591 ! response to oxygen radical GO:0000305 11 6 0,000 0,0324275 0,08845869 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,0324275 0,08835851 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,0324275 0,08825856 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,0324275 0,08815883 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,0324275 0,08805933 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,0324275 0,08796005 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,0324275 0,08786099 ! forebrain regionalization GO:0021871 8 6 0,000 0,0324275 0,08776216 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,0324275 0,08766355 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,0324275 0,08756517 ! response to zinc ion GO:0010043 9 6 0,000 0,0324275 0,087467 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,0324275 0,08736905 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,0324275 0,08727132 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,0324275 0,08717381 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,0324275 0,08707652 ! malate metabolic process GO:0006108 11 6 0,000 0,0324275 0,08697945 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,0324275 0,08688259 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,0324275 0,08678594 ! protein refolding GO:0042026 15 6 0,000 0,0324275 0,08668951 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,0324275 0,0865933 ! opsonization GO:0008228 8 6 0,000 0,0324275 0,0864973 ! mating behavior GO:0007617 7 6 0,000 0,0324275 0,08640151 ! neuron remodeling GO:0016322 15 6 0,000 0,0324275 0,08630593 ! erythrocyte maturation GO:0043249 7 6 0,000 0,0324275 0,08621057 ! equilibrioception GO:0050957 14 6 0,000 0,0324275 0,08611541 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,0324275 0,08602047 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,0324275 0,08592573 ! photoreceptor cell development GO:0042461 10 6 0,000 0,0324275 0,0858312 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,0324275 0,08573688 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,0324275 0,08564277 ! response to interferon-gamma GO:0034341 15 6 0,000 0,0324275 0,08554886 ! toxin metabolic process GO:0009404 11 6 0,000 0,0324275 0,08545516 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,0324275 0,08536167 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,0324275 0,08526837 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,0324275 0,08517529 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,0324275 0,0850824 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,0324275 0,08498972 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,0324275 0,08489724 ! protein lipoylation GO:0009249 10 6 0,000 0,0324275 0,08480496 ! cysteine metabolic process GO:0006534 10 6 0,000 0,0324275 0,08471288 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,0324275 0,084621 ! glutamate catabolic process GO:0006538 10 6 0,000 0,0324275 0,08452932 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,0324275 0,08443784 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,0324275 0,08434655 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,0324275 0,08425547 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,0324275 0,08416458 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,0324275 0,08407388 ! hyperosmotic response GO:0006972 9 6 0,000 0,0324275 0,08398338 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,0324275 0,08389308 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,0324275 0,08380297 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,0324275 0,08371305 ! urea metabolic process GO:0019627 7 6 0,000 0,0324275 0,08362333 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,0324275 0,08353379 ! neutrophil activation GO:0042119 8 6 0,000 0,0324275 0,08344445 ! regulation of appetite GO:0032098 9 6 0,000 0,0324275 0,0833553 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,0324275 0,08326634 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,0324275 0,08317757 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,0324275 0,08308899 ! neuron apoptosis GO:0051402 9 6 0,000 0,0324275 0,0830006 ! nucleoside salvage GO:0043174 9 6 0,000 0,0324275 0,08291239 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,0324275 0,08282438 ! T cell mediated immunity GO:0002456 16 6 0,000 0,0324275 0,08273655 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,0324275 0,0826489 GO:0010543|regulation of platelet activation, ! carnitine transport GO:0015879 10 6 0,000 0,0324275 0,08256144 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,0324275 0,08247417 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,0324275 0,08238708 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,0324275 0,08230017 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,0324275 0,08221345 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,0324275 0,08212691 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,0324275 0,08204055 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,0324275 0,08195437 ! establishment of spindle localization GO:0051293 12 6 0,000 0,0324275 0,08186838 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,0324275 0,08178256 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,0324275 0,08169692 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,0324275 0,08161147 ! neural nucleus development GO:0048857 14 6 0,000 0,0324275 0,08152619 ! astrocyte development GO:0014002 15 6 0,000 0,0324275 0,08144109 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,0324275 0,08135617 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,0324275 0,08127142 ! interaction with symbiont GO:0051702 13 6 0,000 0,0324275 0,08118685 ! regulation of dendrite development GO:0050773 16 6 0,000 0,0324275 0,08110246 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,0324275 0,08101824 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,0324275 0,08093419 ! response to copper ion GO:0046688 10 6 0,000 0,0324275 0,08085032 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,0324275 0,08076663 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,0324275 0,08068311 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,0324275 0,08059975 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,0324275 0,08051658 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,0324275 0,08043357 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,0324275 0,08035073 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,0324275 0,08026807 ! Schwann cell development GO:0014044 15 6 0,000 0,0324275 0,08018557 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,0324275 0,08010325 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,0324275 0,08002109 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,0324275 0,0799391 ! subpallium development GO:0021544 10 6 0,000 0,0324275 0,07985728 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,0324275 0,07977563 ! histone ubiquitination GO:0016574 8 6 0,000 0,0324275 0,07969414 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,0324275 0,07961282 ! maintenance of organ identity GO:0048496 9 6 0,000 0,0324275 0,07953166 ! G2 phase GO:0051319 16 6 0,000 0,0324275 0,07945067 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,0324275 0,07936985 ! establishment of planar polarity GO:0001736 7 6 0,000 0,0324275 0,07928919 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,0324275 0,07920869 ! membrane to membrane docking GO:0022614 14 6 0,000 0,0324275 0,07912836 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,0324275 0,07904819 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,0324275 0,07896818 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,0324275 0,07888833 ! receptor internalization GO:0031623 10 6 0,000 0,0324275 0,07880865 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,0324275 0,07872912 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,0324275 0,07864976 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,0324275 0,07857056 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,0324275 0,07849151 ! protein deubiquitination GO:0016579 14 6 0,000 0,0324275 0,07841263 ! protein destabilization GO:0031648 9 6 0,000 0,0324275 0,0783339 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,0324275 0,07825533 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,0324275 0,07817692 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,0324275 0,07809866 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,0324275 0,07802056 ! progesterone metabolic process GO:0042448 10 6 0,000 0,0324275 0,07794262 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,0324275 0,07786483 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,0324275 0,0777872 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,0324275 0,07770972 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,0324275 0,0776324 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,0324275 0,07755523 ! determination of adult lifespan GO:0008340 15 6 0,000 0,0324275 0,07747822 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,0324275 0,07740135 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,0324275 0,07732464 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,0324275 0,07724808 ! catecholamine transport GO:0051937 9 6 0,000 0,0324275 0,07717167 ! sensory cilium assembly GO:0035058 10 6 0,000 0,0324275 0,07709542 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,0324275 0,07701931 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,0324275 0,07694336 ! maternal placenta development GO:0001893 12 6 0,000 0,0324275 0,07686755 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,0324275 0,07679189 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,0324275 0,07671638 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,0324275 0,07664102 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,0324275 0,07656581 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,0324275 0,07649075 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,0324275 0,07641583 ! synapse organization GO:0050808 85 52 1,000 0,03308272 0,07788358 ! regulation of neuron apoptosis GO:0043523 100 53 1,000 0,03425873 0,08057333 ! regulation of multicellular organism growth GO:0040014 85 55 1,000 0,03665891 0,08613411 ! tRNA transcription GO:0009304 14 7 0,000 0,03772953 0,08856317 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,03772953 0,08847685 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,03772953 0,0883907 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,03772953 0,08830472 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,03772953 0,0882189 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,03772953 0,08813325 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,03772953 0,08804777 ! prostate gland development GO:0030850 13 7 0,000 0,03772953 0,08796245 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,03772953 0,0878773 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,03772953 0,08779231 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,03772953 0,08770749 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,03772953 0,08762283 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,03772953 0,08753833 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,03772953 0,087454 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,03772953 0,08736983 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 0,03772953 0,08728582 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,03772953 0,08720197 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,03772953 0,08711828 ! glycolipid transport GO:0046836 10 7 0,000 0,03772953 0,08703476 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,03772953 0,08695139 GO:0051923|sulfation, ! neuron adhesion GO:0007158 12 7 0,000 0,03772953 0,08686818 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,03772953 0,08678513 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,03772953 0,08670224 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,03772953 0,08661951 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,03772953 0,08653694 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,03772953 0,08645452 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,03772953 0,08637226 ! pericardium development GO:0060039 14 7 0,000 0,03772953 0,08629016 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,03772953 0,08620821 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,03772953 0,08612642 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,03772953 0,08604479 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,03772953 0,0859633 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,03772953 0,08588198 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,03772953 0,0858008 ! lipoprotein transport GO:0042953 14 7 0,000 0,03772953 0,08571978 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,03772953 0,08563892 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,03772953 0,0855582 ! rhythmic behavior GO:0007622 15 7 0,000 0,03772953 0,08547764 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,03772953 0,08539722 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,03772953 0,08531696 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,03772953 0,08523685 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,03772953 0,08515689 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,03772953 0,08507709 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,03772953 0,08499743 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,03772953 0,08491791 ! mechanosensory behavior GO:0007638 14 7 0,000 0,03772953 0,08483855 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,03772953 0,08475934 ! positive regulation of heart rate GO:0010460 10 7 0,000 0,03772953 0,08468027 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,03772953 0,08460135 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,03772953 0,08452258 ! spinal cord patterning GO:0021511 13 7 0,000 0,03772953 0,08444395 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,03772953 0,08436547 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,03772953 0,08428714 ! adrenal gland development GO:0030325 17 7 0,000 0,03772953 0,08420895 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,03772953 0,08413091 ! ovulation GO:0030728 9 7 0,000 0,03772953 0,08405301 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,03772953 0,08397525 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,03772953 0,08389764 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,03772953 0,08382018 ! microtubule nucleation GO:0007020 20 7 0,000 0,03772953 0,08374285 ! proline biosynthetic process GO:0006561 10 7 0,000 0,03772953 0,08366567 ! thyroid hormone generation GO:0006590 13 7 0,000 0,03772953 0,08358863 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,03772953 0,08351173 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,03772953 0,08343497 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,03772953 0,08335836 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,03772953 0,08328188 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,03772953 0,08320555 ! galactose metabolic process GO:0006012 13 7 0,000 0,03772953 0,08312935 ! vesicle fusion GO:0006906 17 7 0,000 0,03772953 0,08305329 ! response to dietary excess GO:0002021 8 7 0,000 0,03772953 0,08297738 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,03772953 0,0829016 ! intracellular pH reduction GO:0051452 11 7 0,000 0,03772953 0,08282596 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,03772953 0,08275046 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,03772953 0,08267509 ! organ growth GO:0035265 15 7 0,000 0,03772953 0,08259986 ! purine salvage GO:0043101 10 7 0,000 0,03772953 0,08252477 ! nucleoside transport GO:0015858 8 7 0,000 0,03772953 0,08244982 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,03772953 0,082375 ! parturition GO:0007567 14 7 0,000 0,03772953 0,08230032 ! rRNA modification GO:0000154 14 7 0,000 0,03772953 0,08222577 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,03772953 0,08215136 ! spindle checkpoint GO:0031577 15 7 0,000 0,03772953 0,08207708 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,03772953 0,08200294 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,03772953 0,08192893 ! macrophage differentiation GO:0030225 11 7 0,000 0,03772953 0,08185505 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,03772953 0,08178131 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,03772953 0,0817077 GO:0046676|negative regulation of insulin secretion, ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,03772953 0,08163422 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,03772953 0,08156087 ! fibrinolysis GO:0042730 10 7 0,000 0,03772953 0,08148766 ! eating behavior GO:0042755 7 7 0,000 0,03772953 0,08141457 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,03772953 0,08134162 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,03772953 0,0812688 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,03772953 0,08119611 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,03772953 0,08112355 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,03772953 0,08105112 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,03772953 0,08097881 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,03772953 0,08090664 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,03772953 0,08083459 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,03772953 0,08076268 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,03772953 0,08069089 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,03772953 0,08061923 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,03772953 0,08054769 ! regulation of meiosis GO:0040020 12 7 0,000 0,03772953 0,08047629 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,03772953 0,080405 ! regulation of lipid transport GO:0032368 14 7 0,000 0,03772953 0,08033385 ! transcription termination GO:0006353 13 7 0,000 0,03772953 0,08026282 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,03772953 0,08019192 ! anaphase GO:0051322 17 7 0,000 0,03772953 0,08012114 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,03772953 0,08005048 ! axonal fasciculation GO:0007413 18 7 0,000 0,03772953 0,07997996 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,03772953 0,07990955 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,03772953 0,07983927 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,03772953 0,07976911 ! diuresis GO:0030146 12 7 0,000 0,03772953 0,07969908 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,03772953 0,07962917 ! thiamin metabolic process GO:0006772 7 7 0,000 0,03772953 0,07955938 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,03772953 0,07948971 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,03772953 0,07942017 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,03772953 0,07935074 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,03772953 0,07928144 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,03772953 0,07921226 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,03772953 0,0791432 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,03772953 0,07907426 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,03772953 0,07900544 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,03772953 0,07893674 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,03772953 0,07886816 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,03772953 0,0787997 ! lymph node development GO:0048535 10 7 0,000 0,03772953 0,07873135 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,03772953 0,07866313 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,03772953 0,07859502 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,03772953 0,07852703 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,03772953 0,07845916 ! adult feeding behavior GO:0008343 9 7 0,000 0,03772953 0,07839141 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,03772953 0,07832377 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,03772953 0,07825625 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,03772953 0,07818885 ! embryonic heart tube development GO:0035050 10 7 0,000 0,03772953 0,07812156 ! retina homeostasis GO:0001895 12 7 0,000 0,03772953 0,07805439 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,03772953 0,07798733 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,03772953 0,07792039 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,03772953 0,07785356 ! protein prenylation GO:0018342 18 7 0,000 0,03772953 0,07778685 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,03772953 0,07772025 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,03772953 0,07765376 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,03772953 0,07758739 ! skeletal muscle fiber development GO:0048741 111 56 1,000 0,03788265 0,07783573 ! regulation of bone remodeling GO:0046850 137 57 1,000 0,03912188 0,08031334 ! muscle fiber development GO:0048747 112 57 1,000 0,03912188 0,08024487 ! maintenance of location GO:0051235 118 57 1,000 0,03912188 0,08017652 ! regulation of tissue remodeling GO:0034103 140 58 1,000 0,0403764 0,08267712 ! regulation of endocytosis GO:0030100 91 58 1,000 0,0403764 0,08260682 ! positive regulation of secretion GO:0051047 95 59 1,000 0,04164601 0,08513194 ! skeletal system morphogenesis GO:0048705 105 59 1,000 0,04164601 0,08505968 ! regulation of Rab protein signal transduction GO:0032483 92 59 1,000 0,04164601 0,08498753 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 1,000 0,04164601 0,08491551 ! DNA catabolic process GO:0006308 86 59 1,000 0,04164601 0,08484361 ! integrin-mediated signaling pathway GO:0007229 135 59 1,000 0,04164601 0,08477183 ! camera-type eye development GO:0043010 116 60 1,000 0,0429305 0,08731259 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,04300268 0,08738552 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,04300268 0,08731178 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,04300268 0,08723816 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,04300268 0,08716466 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,04300268 0,08709129 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,04300268 0,08701804 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,04300268 0,08694492 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,04300268 0,08687192 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,04300268 0,08679904 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,04300268 0,08672628 ! meiotic prophase I GO:0007128 13 8 0,000 0,04300268 0,08665365 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,04300268 0,08658113 ! oligopeptide transport GO:0006857 15 8 0,000 0,04300268 0,08650874 ! UTP metabolic process GO:0046051 8 8 0,000 0,04300268 0,08643647 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,04300268 0,08636432 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,04300268 0,08629229 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,04300268 0,08622038 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,04300268 0,08614859 ! succinate metabolic process GO:0006105 14 8 0,000 0,04300268 0,08607692 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,04300268 0,08600537 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,04300268 0,08593393 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,04300268 0,08586262 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,04300268 0,08579142 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,04300268 0,08572034 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,04300268 0,08564938 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,04300268 0,08557854 ! reflex GO:0060004 16 8 0,000 0,04300268 0,08550781 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,04300268 0,08543721 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,04300268 0,08536671 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,04300268 0,08529634 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,04300268 0,08522608 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,04300268 0,08515593 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,04300268 0,0850859 ! pigment granule organization GO:0048753 16 8 0,000 0,04300268 0,08501599 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,04300268 0,08494619 ! astrocyte differentiation GO:0048708 18 8 0,000 0,04300268 0,0848765 ! histidine metabolic process GO:0006547 16 8 0,000 0,04300268 0,08480693 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,04300268 0,08473747 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,04300268 0,08466813 ! glycine catabolic process GO:0006546 13 8 0,000 0,04300268 0,0845989 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,04300268 0,08452978 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,04300268 0,08446078 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,04300268 0,08439189 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,04300268 0,08432311 ! melanin metabolic process GO:0006582 15 8 0,000 0,04300268 0,08425444 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,04300268 0,08418589 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,04300268 0,08411744 ! macrophage activation GO:0042116 12 8 0,000 0,04300268 0,08404911 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,04300268 0,08398089 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,04300268 0,08391278 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,04300268 0,08384478 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,04300268 0,08377689 ! osteoblast development GO:0002076 16 8 0,000 0,04300268 0,08370911 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,04300268 0,08364144 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,04300268 0,08357387 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,04300268 0,08350642 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,04300268 0,08343908 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,04300268 0,08337184 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,04300268 0,08330471 ! response to UV-B GO:0010224 16 8 0,000 0,04300268 0,0832377 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,04300268 0,08317078 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,04300268 0,08310398 ! intermediate filament organization GO:0045109 12 8 0,000 0,04300268 0,08303728 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,04300268 0,08297069 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,04300268 0,08290421 ! cellular extravasation GO:0045123 12 8 0,000 0,04300268 0,08283783 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,04300268 0,08277156 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,04300268 0,0827054 ! response to antibiotic GO:0046677 11 8 0,000 0,04300268 0,08263934 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,04300268 0,08257339 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,04300268 0,08250754 ! DNA topological change GO:0006265 12 8 0,000 0,04300268 0,0824418 ! response to tropane GO:0014073 15 8 0,000 0,04300268 0,08237616 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,04300268 0,08231062 ! melanosome transport GO:0032402 13 8 0,000 0,04300268 0,0822452 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,04300268 0,08217987 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,04300268 0,08211465 ! mast cell activation GO:0045576 14 8 0,000 0,04300268 0,08204953 ! multicellular organismal aging GO:0010259 18 8 0,000 0,04300268 0,08198451 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,04300268 0,0819196 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,04300268 0,08185479 ! nucleosome disassembly GO:0006337 14 8 0,000 0,04300268 0,08179008 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,04300268 0,08172548 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,04300268 0,08166097 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,04300268 0,08159657 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,04300268 0,08153227 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,04300268 0,08146808 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,04300268 0,08140398 ! intracellular lipid transport GO:0032365 13 8 0,000 0,04300268 0,08133998 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,04300268 0,08127608 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,04300268 0,08121229 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,04300268 0,08114859 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,04300268 0,081085 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,04300268 0,0810215 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,04300268 0,0809581 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,04300268 0,0808948 ! hormone catabolic process GO:0042447 17 8 0,000 0,04300268 0,08083161 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,04300268 0,08076851 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,04300268 0,0807055 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,04300268 0,0806426 ! ATP catabolic process GO:0006200 11 8 0,000 0,04300268 0,08057979 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,04300268 0,08051709 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,04300268 0,08045448 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,04300268 0,08039196 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,04300268 0,08032955 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,04300268 0,08026723 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,04300268 0,080205 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,04300268 0,08014288 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,04300268 0,08008085 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,04300268 0,08001891 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,04300268 0,07995708 GO:0006043|glucosamine catabolic process, ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,04300268 0,07989533 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,04300268 0,07983368 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,04300268 0,07977213 GO:0000076|DNA replication checkpoint, ! NAD biosynthetic process GO:0009435 13 8 0,000 0,04300268 0,07971067 ! viral reproductive process GO:0022415 126 62 1,000 0,04554336 0,08435514 ! gonad development GO:0008406 98 62 1,000 0,04554336 0,08429025 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 1,000 0,04821339 0,08916328 ! axon extension GO:0048675 15 9 0,000 0,04824711 0,08915711 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,04824711 0,08908868 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,04824711 0,08902036 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,04824711 0,08895215 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,04824711 0,08888404 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,04824711 0,08881603 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,04824711 0,08874813 ! phosphate transport GO:0006817 19 9 0,000 0,04824711 0,08868033 ! reproductive behavior GO:0019098 19 9 0,000 0,04824711 0,08861264 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,04824711 0,08854505 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,04824711 0,08847756 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,04824711 0,08841017 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,04824711 0,08834289 ! GTP metabolic process GO:0046039 9 9 0,000 0,04824711 0,08827571 ! RNA methylation GO:0001510 15 9 0,000 0,04824711 0,08820863 ! elastic fiber assembly GO:0048251 15 9 0,000 0,04824711 0,08814165 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,04824711 0,08807478 ! artery development GO:0060840 24 9 0,000 0,04824711 0,088008 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,04824711 0,08794133 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,04824711 0,08787476 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,04824711 0,08780829 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,04824711 0,08774192 ! chemosensory behavior GO:0007635 20 9 0,000 0,04824711 0,08767565 ! microtubule bundle formation GO:0001578 21 9 0,000 0,04824711 0,08760948 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,04824711 0,08754341 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,04824711 0,08747743 ! leukocyte degranulation GO:0043299 16 9 0,000 0,04824711 0,08741156 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,04824711 0,08734579 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,04824711 0,08728012 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,04824711 0,08721454 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,04824711 0,08714907 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,04824711 0,08708369 ! protein targeting to ER GO:0045047 22 9 0,000 0,04824711 0,08701841 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,04824711 0,08695322 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,04824711 0,08688814 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,04824711 0,08682315 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,04824711 0,08675826 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,04824711 0,08669347 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,04824711 0,08662877 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,04824711 0,08656417 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,04824711 0,08649967 ! mannose metabolic process GO:0006013 13 9 0,000 0,04824711 0,08643526 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,04824711 0,08637095 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,04824711 0,08630673 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,04824711 0,08624261 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,04824711 0,08617859 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,04824711 0,08611466 ! ruffle organization GO:0031529 15 9 0,000 0,04824711 0,08605082 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,04824711 0,08598708 ! behavioral fear response GO:0001662 22 9 0,000 0,04824711 0,08592343 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,04824711 0,08585988 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,04824711 0,08579642 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,04824711 0,08573305 GO:0030204|chondroitin sulfate metabolic process, ! oligodendrocyte development GO:0014003 10 9 0,000 0,04824711 0,08566978 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,04824711 0,0856066 ! segment specification GO:0007379 13 9 0,000 0,04824711 0,08554352 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,04824711 0,08548053 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,04824711 0,08541763 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,04824711 0,08535482 ! response to amine stimulus GO:0014075 13 9 0,000 0,04824711 0,08529211 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,04824711 0,08522948 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,04824711 0,08516695 ! erythrocyte development GO:0048821 15 9 0,000 0,04824711 0,08510451 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,04824711 0,08504216 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,04824711 0,08497991 ! renal water homeostasis GO:0003091 14 9 0,000 0,04824711 0,08491774 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,04824711 0,08485567 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,04824711 0,08479369 ! icosanoid secretion GO:0032309 15 9 0,000 0,04824711 0,08473179 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,04824711 0,08466999 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,04824711 0,08460828 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,04824711 0,08454665 ! regulation of cell division GO:0051302 15 9 0,000 0,04824711 0,08448512 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,04824711 0,08442368 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,04824711 0,08436232 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,04824711 0,08430106 ! sterol catabolic process GO:0016127 11 9 0,000 0,04824711 0,08423988 GO:0006707|cholesterol catabolic process, ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,04824711 0,08417879 ! S phase GO:0051320 9 9 0,000 0,04824711 0,08411779 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,04824711 0,08405688 ! musculoskeletal movement GO:0050881 14 9 0,000 0,04824711 0,08399606 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,04824711 0,08393533 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,04824711 0,08387468 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,04824711 0,08381412 ! purine base metabolic process GO:0006144 21 9 0,000 0,04824711 0,08375365 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,04824711 0,08369326 ! pigment granule transport GO:0051904 17 9 0,000 0,04824711 0,08363296 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,04824711 0,08357275 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,04824711 0,08351263 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,04824711 0,08345259 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,04824711 0,08339264 ! mitochondrion localization GO:0051646 15 9 0,000 0,04824711 0,08333277 ! embryonic limb morphogenesis GO:0030326 125 65 1,000 0,04956937 0,08555517 GO:0035113|embryonic appendage morphogenesis, ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 1,000 0,05093906 0,08785619 ! secondary metabolic process GO:0019748 116 66 1,000 0,05093906 0,08779325 ! cellular hormone metabolic process GO:0034754 113 67 1,000 0,05232228 0,09011268 ! chromosome segregation GO:0007059 113 67 1,000 0,05232228 0,09004822 ! regulation of cellular response to stress GO:0080135 128 67 1,000 0,05232228 0,08998385 ! homeostasis of number of cells GO:0048872 114 67 1,000 0,05232228 0,08991958 ! positive regulation of T cell activation GO:0050870 109 67 1,000 0,05232228 0,0898554 ! adaptive immune response GO:0002250 119 67 1,000 0,05232228 0,08979131 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 1,000 0,05232228 0,08972731 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,05346298 0,09161818 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,05346298 0,09155297 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,05346298 0,09148785 ! synapsis GO:0007129 13 10 0,000 0,05346298 0,09142283 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,05346298 0,0913579 ! N-glycan processing GO:0006491 20 10 0,000 0,05346298 0,09129306 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,05346298 0,09122831 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,05346298 0,09116366 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,05346298 0,0910991 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,05346298 0,09103462 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,05346298 0,09097024 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,05346298 0,09090595 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,05346298 0,09084175 ! androgen metabolic process GO:0008209 17 10 0,000 0,05346298 0,09077765 ! phospholipid efflux GO:0033700 16 10 0,000 0,05346298 0,09071363 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,05346298 0,0906497 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,05346298 0,09058586 ! pathogenesis GO:0009405 13 10 0,000 0,05346298 0,09052211 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,05346298 0,09045846 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,05346298 0,09039489 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,05346298 0,09033141 ! endoderm development GO:0007492 16 10 0,000 0,05346298 0,09026802 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,05346298 0,09020471 ! arginine catabolic process GO:0006527 13 10 0,000 0,05346298 0,0901415 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,05346298 0,09007838 ! proline metabolic process GO:0006560 13 10 0,000 0,05346298 0,09001534 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,05346298 0,08995239 ! V(D)J recombination GO:0033151 28 10 0,000 0,05346298 0,08988953 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,05346298 0,08982676 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,05346298 0,08976408 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,05346298 0,08970148 ! B cell proliferation GO:0042100 18 10 0,000 0,05346298 0,08963897 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,05346298 0,08957655 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,05346298 0,08951421 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,05346298 0,08945196 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,05346298 0,0893898 ! epithelial cell development GO:0002064 20 10 0,000 0,05346298 0,08932772 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,05346298 0,08926573 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,05346298 0,08920383 ! macroautophagy GO:0016236 17 10 0,000 0,05346298 0,08914201 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,05346298 0,08908028 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,05346298 0,08901863 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,05346298 0,08895707 ! copper ion homeostasis GO:0055070 13 10 0,000 0,05346298 0,08889559 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,05346298 0,0888342 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,05346298 0,08877289 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,05346298 0,08871167 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,05346298 0,08865053 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,05346298 0,08858948 ! blastoderm segmentation GO:0007350 18 10 0,000 0,05346298 0,08852851 ! response to dsRNA GO:0043331 20 10 0,000 0,05346298 0,08846762 ! DNA ligation GO:0006266 19 10 0,000 0,05346298 0,08840682 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,05346298 0,0883461 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,05346298 0,08828547 ! melanosome localization GO:0032400 16 10 0,000 0,05346298 0,08822491 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,05346298 0,08816444 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,05346298 0,08810406 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,05346298 0,08804375 ! mRNA cleavage GO:0006379 17 10 0,000 0,05346298 0,08798353 ! protein sumoylation GO:0016925 15 10 0,000 0,05346298 0,08792339 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,05346298 0,08786334 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,05346298 0,08780336 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,05346298 0,08774347 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,05346298 0,08768366 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,05346298 0,08762393 ! salivary gland development GO:0007431 27 10 0,000 0,05346298 0,08756428 ! prophase GO:0051324 15 10 0,000 0,05346298 0,08750471 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,05346298 0,08744522 ! apical protein localization GO:0045176 15 10 0,000 0,05346298 0,08738582 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,05346298 0,08732649 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,05346298 0,08726725 ! midbrain development GO:0030901 13 10 0,000 0,05346298 0,08720808 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,05346298 0,087149 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,05346298 0,08709 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,05346298 0,08703107 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,05346298 0,08697223 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,05346298 0,08691346 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,05346298 0,08685478 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,05346298 0,08679617 ! detection of calcium ion GO:0005513 23 10 0,000 0,05346298 0,08673764 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,05346298 0,08667919 ! blastocyst formation GO:0001825 17 10 0,000 0,05346298 0,08662082 ! cerebellar cortex development GO:0021695 15 10 0,000 0,05346298 0,08656253 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,05346298 0,08650432 ! activation of innate immune response GO:0002218 12 10 0,000 0,05346298 0,08644618 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,05346298 0,08638813 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,05346298 0,08633015 ! response to nicotine GO:0035094 20 10 0,000 0,05346298 0,08627225 ! establishment of cell polarity GO:0030010 16 10 0,000 0,05346298 0,08621443 ! amino acid transport GO:0006865 125 68 1,000 0,05371885 0,08656902 ! cAMP-mediated signaling GO:0019933 120 69 1,000 0,05512856 0,08878134 ! appendage morphogenesis GO:0035107 135 70 1,000 0,05655125 0,09101158 GO:0035108|limb morphogenesis, ! appendage development GO:0048736 136 71 1,000 0,05798673 0,09325941 GO:0060173|limb development, ! B cell activation GO:0042113 160 71 1,000 0,05798673 0,09319711 ! regulation of MAPKKK cascade GO:0043408 142 71 1,000 0,05798673 0,0931349 ! respiratory burst GO:0045730 17 11 0,000 0,05865043 0,09413805 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,05865043 0,09407529 ! neuron fate specification GO:0048665 17 11 0,000 0,05865043 0,09401261 ! telencephalon cell migration GO:0022029 20 11 0,000 0,05865043 0,09395002 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,05865043 0,09388751 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,05865043 0,09382509 ! thyroid gland development GO:0030878 26 11 0,000 0,05865043 0,09376275 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,05865043 0,09370049 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,05865043 0,09363831 ! response to pain GO:0048265 24 11 0,000 0,05865043 0,09357621 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,05865043 0,0935142 ! bone resorption GO:0045453 16 11 0,000 0,05865043 0,09345227 ! ventral spinal cord development GO:0021517 21 11 0,000 0,05865043 0,09339042 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,05865043 0,09332866 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,05865043 0,09326697 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,05865043 0,09320537 ! melanocyte differentiation GO:0030318 21 11 0,000 0,05865043 0,09314385 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,05865043 0,09308241 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,05865043 0,09302105 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,05865043 0,09295977 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,05865043 0,09289857 GO:0043088|regulation of Cdc42 GTPase activity, ! lipid digestion GO:0044241 18 11 0,000 0,05865043 0,09283746 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,05865043 0,09277642 ! UV protection GO:0009650 19 11 0,000 0,05865043 0,09271546 ! adult heart development GO:0007512 14 11 0,000 0,05865043 0,09265458 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,05865043 0,09259379 ! temperature homeostasis GO:0001659 17 11 0,000 0,05865043 0,09253307 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,05865043 0,09247243 ! negative regulation of ossification GO:0030279 26 11 0,000 0,05865043 0,09241187 ! regulation of organ growth GO:0046620 13 11 0,000 0,05865043 0,0923514 ! pigment granule localization GO:0051875 20 11 0,000 0,05865043 0,092291 ! vasoconstriction GO:0042310 18 11 0,000 0,05865043 0,09223067 ! embryonic axis specification GO:0000578 18 11 0,000 0,05865043 0,09217043 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,05865043 0,09211027 ! snRNA metabolic process GO:0016073 24 11 0,000 0,05865043 0,09205018 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,05865043 0,09199018 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,05865043 0,09193025 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,05865043 0,0918704 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,05865043 0,09181063 ! zymogen activation GO:0031638 15 11 0,000 0,05865043 0,09175093 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,05865043 0,09169131 ! neuroblast proliferation GO:0007405 24 11 0,000 0,05865043 0,09163177 ! nucleosome positioning GO:0016584 15 11 0,000 0,05865043 0,09157231 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,05865043 0,09151293 ! acid secretion GO:0046717 18 11 0,000 0,05865043 0,09145362 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,05865043 0,09139439 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,05865043 0,09133523 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,05865043 0,09127615 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,05865043 0,09121715 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,05865043 0,09115822 ! cholesterol efflux GO:0033344 19 11 0,000 0,05865043 0,09109938 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,05865043 0,0910406 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,05865043 0,0909819 ! germ cell migration GO:0008354 25 11 0,000 0,05865043 0,09092328 ! embryonic gut development GO:0048566 15 11 0,000 0,05865043 0,09086473 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,05865043 0,09080626 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,05865043 0,09074787 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,05865043 0,09068955 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,05865043 0,0906313 ! defense response to fungus GO:0050832 13 11 0,000 0,05865043 0,09057313 ! developmental induction GO:0031128 19 11 0,000 0,05865043 0,09051503 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,05865043 0,09045701 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,05865043 0,09039906 ! sequestering of metal ion GO:0051238 14 11 0,000 0,05865043 0,09034119 ! lamellipodium assembly GO:0030032 20 11 0,000 0,05865043 0,09028339 ! nucleus localization GO:0051647 19 11 0,000 0,05865043 0,09022566 ! regulation of synapse organization GO:0050807 17 11 0,000 0,05865043 0,09016801 ! carbohydrate transport GO:0008643 110 72 1,000 0,05943482 0,09131556 ! regulation of blood pressure GO:0008217 125 73 1,000 0,06089533 0,09349979 ! meiosis GO:0007126 121 74 1,000 0,0623681 0,09570003 GO:0051327|M phase of meiotic cell cycle, ! eye development GO:0001654 143 74 1,000 0,0623681 0,09563903 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,06380962 0,09778723 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,06380962 0,09772499 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,06380962 0,09766282 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,06380962 0,09760073 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,06380962 0,09753872 ! mating GO:0007618 17 12 0,000 0,06380962 0,09747679 ! protein complex disassembly GO:0043241 27 12 0,000 0,06380962 0,09741494 GO:0043624|cellular protein complex disassembly, ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,06380962 0,09735317 ! hippocampus development GO:0021766 26 12 0,000 0,06380962 0,09729148 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,06380962 0,09722986 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,06380962 0,09716832 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,06380962 0,09710686 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,06380962 0,09704548 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,06380962 0,09698418 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,06380962 0,09692295 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,06380962 0,0968618 ! drug transport GO:0015893 16 12 0,000 0,06380962 0,09680073 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,06380962 0,09673973 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,06380962 0,09667881 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,06380962 0,09661797 ! polyamine metabolic process GO:0006595 17 12 0,000 0,06380962 0,0965572 ! mitotic spindle organization GO:0007052 21 12 0,000 0,06380962 0,09649651 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,06380962 0,0964359 ! forebrain cell migration GO:0021885 21 12 0,000 0,06380962 0,09637536 ! asymmetric protein localization GO:0008105 20 12 0,000 0,06380962 0,0963149 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,06380962 0,09625452 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,06380962 0,09619421 ! entry into host cell GO:0030260 32 12 0,000 0,06380962 0,09613397 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,06380962 0,09607381 ! monoamine transport GO:0015844 18 12 0,000 0,06380962 0,09601373 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,06380962 0,09595372 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,06380962 0,09589379 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,06380962 0,09583393 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,06380962 0,09577414 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,06380962 0,09571443 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,06380962 0,0956548 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,06380962 0,09559524 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,06380962 0,09553575 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,06380962 0,09547634 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,06380962 0,095417 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,06380962 0,09535773 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,06380962 0,09529854 ! cranial nerve development GO:0021545 20 12 0,000 0,06380962 0,09523942 ! fucose catabolic process GO:0019317 22 12 0,000 0,06380962 0,09518038 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,06380962 0,09512141 ! histone methylation GO:0016571 26 12 0,000 0,06380962 0,09506251 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,06380962 0,09500368 ! gland morphogenesis GO:0022612 29 12 0,000 0,06380962 0,09494493 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,06380962 0,09488625 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,06380962 0,09482764 ! spleen development GO:0048536 22 12 0,000 0,06380962 0,09476911 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,06380962 0,09471064 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,06380962 0,09465225 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,06380962 0,09459393 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,06380962 0,09453568 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,06380962 0,09447751 ! response to cold GO:0009409 17 12 0,000 0,06380962 0,0944194 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,06380962 0,09436137 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,06380962 0,09430341 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 1,000 0,06385294 0,0943095 ! regulation of vesicle-mediated transport GO:0060627 119 75 1,000 0,06385294 0,09425164 ! meiotic cell cycle GO:0051321 122 75 1,000 0,06385294 0,09419385 ! cytosolic calcium ion homeostasis GO:0051480 135 76 1,000 0,06534968 0,09634273 ! response to steroid hormone stimulus GO:0048545 137 78 1,000 0,06837817 0,1007458 ! cGMP metabolic process GO:0046068 18 13 0,000 0,06894071 0,10151245 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,06894071 0,10145037 ! peroxisomal transport GO:0043574 24 13 0,000 0,06894071 0,10138836 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,06894071 0,10132642 ! lipid localization GO:0010876 28 13 0,000 0,06894071 0,10126456 GO:0019915|lipid storage, ! organelle fusion GO:0048284 32 13 0,000 0,06894071 0,10120278 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,06894071 0,10114107 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,06894071 0,10107943 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,06894071 0,10101787 ! endocrine pancreas development GO:0031018 22 13 0,000 0,06894071 0,10095639 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,06894071 0,10089498 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,06894071 0,10083365 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,06894071 0,10077239 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,06894071 0,1007112 ! methionine metabolic process GO:0006555 27 13 0,000 0,06894071 0,10065009 ! plasma membrane organization GO:0007009 24 13 0,000 0,06894071 0,10058905 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,06894071 0,10052809 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,06894071 0,1004672 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,06894071 0,10040639 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,06894071 0,10034564 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,06894071 0,10028498 ! cytokine metabolic process GO:0042107 22 13 0,000 0,06894071 0,10022438 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,06894071 0,10016386 ! exocrine system development GO:0035272 32 13 0,000 0,06894071 0,10010341 ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,06894071 0,10004303 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,06894071 0,09998273 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,06894071 0,0999225 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,06894071 0,09986234 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,06894071 0,09980226 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,06894071 0,09974224 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,06894071 0,0996823 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,06894071 0,09962243 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,06894071 0,09956264 ! ribosome assembly GO:0042255 17 13 0,000 0,06894071 0,09950291 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,06894071 0,09944326 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,06894071 0,09938367 ! chromatin silencing GO:0006342 26 13 0,000 0,06894071 0,09932416 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,06894071 0,09926472 ! regulation of epidermis development GO:0045682 19 13 0,000 0,06894071 0,09920535 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,06894071 0,09914605 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,06894071 0,09908683 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,06894071 0,09902767 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,06894071 0,09896859 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,06894071 0,09890957 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,06894071 0,09885063 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,06894071 0,09879175 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,06894071 0,09873295 ! insulin secretion GO:0030073 23 13 0,000 0,06894071 0,09867421 ! actin filament polymerization GO:0030041 24 13 0,000 0,06894071 0,09861555 ! acrosome reaction GO:0007340 18 13 0,000 0,06894071 0,09855695 ! activation of protein kinase activity GO:0032147 147 79 1,000 0,06990958 0,09988269 ! regulation of synaptic transmission GO:0050804 134 79 1,000 0,06990958 0,09982342 ! regulation of adenylate cyclase activity GO:0045761 156 80 1,000 0,07145221 0,10196561 ! digestion GO:0007586 112 81 1,000 0,07300588 0,10412102 ! rRNA transcription GO:0009303 25 14 0,000 0,07404385 0,1055388 ! lactation GO:0007595 26 14 0,000 0,07404385 0,10547631 ! reproductive cellular process GO:0048610 20 14 0,000 0,07404385 0,1054139 ! tRNA modification GO:0006400 20 14 0,000 0,07404385 0,10535156 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,07404385 0,1052893 ! water transport GO:0006833 21 14 0,000 0,07404385 0,10522711 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,07404385 0,10516499 ! non-recombinational repair GO:0000726 25 14 0,000 0,07404385 0,10510295 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,07404385 0,10504097 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,07404385 0,10497908 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,07404385 0,10491725 ! RNA polyadenylation GO:0043631 30 14 0,000 0,07404385 0,1048555 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,07404385 0,10479382 ! palate development GO:0060021 31 14 0,000 0,07404385 0,10473221 ! regulated secretory pathway GO:0045055 23 14 0,000 0,07404385 0,10467068 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,07404385 0,10460922 ! arginine metabolic process GO:0006525 17 14 0,000 0,07404385 0,10454782 ! regulation of heart rate GO:0002027 24 14 0,000 0,07404385 0,10448651 ! organic alcohol transport GO:0015850 29 14 0,000 0,07404385 0,10442526 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,07404385 0,10436409 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,07404385 0,10430298 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,07404385 0,10424195 ! neutral amino acid transport GO:0015804 26 14 0,000 0,07404385 0,10418099 ! L-amino acid transport GO:0015807 30 14 0,000 0,07404385 0,1041201 ! stem cell development GO:0048864 43 14 0,000 0,07404385 0,10405928 GO:0019827|stem cell maintenance, ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,07404385 0,10399854 ! cerebellum development GO:0021549 21 14 0,000 0,07404385 0,10393786 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,07404385 0,10387726 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,07404385 0,10381672 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,07404385 0,10375626 ! cofactor transport GO:0051181 26 14 0,000 0,07404385 0,10369586 ! NADP metabolic process GO:0006739 24 14 0,000 0,07404385 0,10363554 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,07404385 0,10357529 ! intestinal absorption GO:0050892 25 14 0,000 0,07404385 0,1035151 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,07404385 0,10345499 ! oxygen transport GO:0015671 21 14 0,000 0,07404385 0,10339495 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,07404385 0,10333497 ! male genitalia development GO:0030539 24 14 0,000 0,07404385 0,10327507 ! regulation of axon extension GO:0030516 37 14 0,000 0,07404385 0,10321523 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,07404385 0,10315547 ! regulation of cAMP biosynthetic process GO:0030817 161 82 1,000 0,07457044 0,10382899 ! response to drug GO:0042493 143 82 1,000 0,07457044 0,10376893 ! regulation of cyclase activity GO:0031279 159 82 1,000 0,07457044 0,10370895 ! regulation of lyase activity GO:0051339 160 83 1,000 0,07614572 0,1058386 ! regulation of cAMP metabolic process GO:0030814 168 84 1,000 0,07773156 0,10798045 ! regulation of transmission of nerve impulse GO:0051969 141 84 1,000 0,07773156 0,10791814 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,07911918 0,10978128 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,07911918 0,10971801 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,07911918 0,10965481 ! superoxide anion generation GO:0042554 20 15 0,000 0,07911918 0,10959168 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,07911918 0,10952862 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,07911918 0,10946564 ! copper ion transport GO:0006825 20 15 0,000 0,07911918 0,10940273 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,07911918 0,10933989 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,07911918 0,10927712 ! sulfate transport GO:0008272 23 15 0,000 0,07911918 0,10921443 ! response to cAMP GO:0051591 22 15 0,000 0,07911918 0,1091518 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,07911918 0,10908925 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,07911918 0,10902677 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,07911918 0,10896437 ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,07911918 0,10890203 ! response to hexose stimulus GO:0009746 22 15 0,000 0,07911918 0,10883976 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,07911918 0,10877757 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,07911918 0,10871545 ! pituitary gland development GO:0021983 29 15 0,000 0,07911918 0,10865339 ! vesicle coating GO:0006901 33 15 0,000 0,07911918 0,10859141 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,07911918 0,1085295 ! regulation of exocytosis GO:0017157 22 15 0,000 0,07911918 0,10846766 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,07911918 0,10840589 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,07911918 0,10834419 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,07911918 0,10828256 ! regulation of vasodilation GO:0042312 26 15 0,000 0,07911918 0,108221 ! histone deacetylation GO:0016575 20 15 0,000 0,07911918 0,10815951 ! tissue regeneration GO:0042246 26 15 0,000 0,07911918 0,1080981 ! water homeostasis GO:0030104 27 15 0,000 0,07911918 0,10803675 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,07911918 0,10797547 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,07911918 0,10791426 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,07911918 0,10785311 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,07911918 0,10779204 ! dopamine metabolic process GO:0042417 35 15 0,000 0,07911918 0,10773104 ! heme biosynthetic process GO:0006783 29 15 0,000 0,07911918 0,10767011 ! cell killing GO:0001906 29 15 0,000 0,07911918 0,10760924 ! detection of bacterium GO:0016045 18 15 0,000 0,07911918 0,10754844 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,07911918 0,10748772 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,07911918 0,10742706 ! peptide hormone processing GO:0016486 23 15 0,000 0,07911918 0,10736647 ! one-carbon metabolic process GO:0006730 154 85 1,000 0,07932779 0,10758888 ! amine transport GO:0015837 155 86 1,000 0,08093426 0,10970582 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 1,000 0,08255081 0,11183403 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,08416686 0,11395918 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,08416686 0,11389509 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,08416686 0,11383107 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,08416686 0,11376712 ! bone remodeling GO:0046849 27 16 0,000 0,08416686 0,11370324 ! filopodium assembly GO:0046847 32 16 0,000 0,08416686 0,11363943 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,08416686 0,1135757 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,08416686 0,11351203 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,08416686 0,11344844 ! startle response GO:0001964 28 16 0,000 0,08416686 0,11338492 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,08416686 0,11332147 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,08416686 0,11325809 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,08416686 0,11319478 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,08416686 0,11313155 ! protein polyubiquitination GO:0000209 34 16 0,000 0,08416686 0,11306838 ! glutamate metabolic process GO:0006536 22 16 0,000 0,08416686 0,11300528 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,08416686 0,11294226 ! response to osmotic stress GO:0006970 25 16 0,000 0,08416686 0,1128793 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,08416686 0,11281642 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,08416686 0,1127536 ! fructose metabolic process GO:0006000 25 16 0,000 0,08416686 0,11269086 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,08416686 0,11262818 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,08416686 0,11256558 ! intermediate filament-based process GO:0045103 32 16 0,000 0,08416686 0,11250304 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,08416686 0,11244057 ! axon cargo transport GO:0008088 43 16 0,000 0,08416686 0,11237817 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,08416686 0,11231585 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,08416686 0,11225359 ! DNA replication initiation GO:0006270 27 16 0,000 0,08416686 0,1121914 ! neuron recognition GO:0008038 35 16 0,000 0,08416686 0,11212927 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,08416686 0,11206722 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,08416686 0,11200524 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,08416686 0,11194332 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,08416686 0,11188147 GO:0046466|membrane lipid catabolic process, ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,08416686 0,1118197 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,08416686 0,11175799 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,08416686 0,11169634 ! regulation of neurological system process GO:0031644 148 88 1,000 0,08417727 0,11164858 ! regulation of cell morphogenesis GO:0022604 215 89 1,000 0,08581351 0,11375609 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 1,000 0,08745935 0,115874 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,08918704 0,11809798 ! metencephalon development GO:0022037 30 17 0,000 0,08918704 0,11803302 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,08918704 0,11796813 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,08918704 0,11790331 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,08918704 0,11783856 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,08918704 0,11777389 ! gene silencing by RNA GO:0031047 36 17 0,000 0,08918704 0,11770928 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,08918704 0,11764475 ! glial cell development GO:0021782 27 17 0,000 0,08918704 0,11758029 ! limbic system development GO:0021761 36 17 0,000 0,08918704 0,1175159 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,08918704 0,11745157 ! adult walking behavior GO:0007628 33 17 0,000 0,08918704 0,11738732 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,08918704 0,11732314 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,08918704 0,11725903 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,08918704 0,11719499 ! myoblast differentiation GO:0045445 45 17 0,000 0,08918704 0,11713102 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,08918704 0,11706712 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,08918704 0,11700329 ! glycine metabolic process GO:0006544 28 17 0,000 0,08918704 0,11693952 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,08918704 0,11687583 ! NAD metabolic process GO:0019674 29 17 0,000 0,08918704 0,11681221 ! membrane budding GO:0006900 37 17 0,000 0,08918704 0,11674865 ! DNA integration GO:0015074 29 17 0,000 0,08918704 0,11668517 ! regulation of protein binding GO:0043393 33 17 0,000 0,08918704 0,11662175 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,08918704 0,11655841 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,08918704 0,11649513 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,08918704 0,11643192 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,08918704 0,11636878 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,08918704 0,1163057 ! steroid catabolic process GO:0006706 31 17 0,000 0,08918704 0,1162427 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,08918704 0,11617976 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,08918704 0,1161169 ! gas transport GO:0015669 25 17 0,000 0,08918704 0,1160541 ! organic cation transport GO:0015695 31 17 0,000 0,08918704 0,11599136 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,08918704 0,1159287 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,08918704 0,1158661 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,08918704 0,11580358 ! vitamin metabolic process GO:0006766 139 92 1,000 0,09077925 0,11780738 ! regulation of nucleotide metabolic process GO:0006140 182 93 1,000 0,09245302 0,1199148 ! regulation of membrane potential GO:0042391 164 93 1,000 0,09245302 0,11985019 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,09417987 0,12202303 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,09417987 0,12195736 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,09417987 0,12189175 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,09417987 0,12182622 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,09417987 0,12176076 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,09417987 0,12169537 ! memory GO:0007613 31 18 0,000 0,09417987 0,12163004 ! negative regulation of ion transport GO:0043271 24 18 0,000 0,09417987 0,12156479 ! patterning of blood vessels GO:0001569 39 18 0,000 0,09417987 0,12149961 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,09417987 0,1214345 GO:0042744|hydrogen peroxide catabolic process, ! epidermis morphogenesis GO:0048730 40 18 0,000 0,09417987 0,12136945 ! glutamine metabolic process GO:0006541 29 18 0,000 0,09417987 0,12130448 ! response to fungus GO:0009620 21 18 0,000 0,09417987 0,12123958 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,09417987 0,12117474 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,09417987 0,12110998 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,09417987 0,12104528 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,09417987 0,12098066 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,09417987 0,1209161 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,09417987 0,12085161 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,09417987 0,12078719 ! nerve development GO:0021675 28 18 0,000 0,09417987 0,12072284 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,09417987 0,12065856 ! positive regulation of immune response GO:0050778 156 96 1,000 0,09752776 0,12488121 ! protein secretion GO:0009306 39 19 0,000 0,0991455 0,12688514 ! positive regulation of translation GO:0045727 30 19 0,000 0,0991455 0,12681768 ! skin development GO:0043588 36 19 0,000 0,0991455 0,1267503 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,0991455 0,12668299 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,0991455 0,12661574 ! bile acid metabolic process GO:0008206 29 19 0,000 0,0991455 0,12654857 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,0991455 0,12648148 ! cerebral cortex development GO:0021987 36 19 0,000 0,0991455 0,12641445 ! pigmentation during development GO:0048066 41 19 0,000 0,0991455 0,12634749 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,0991455 0,1262806 GO:0030968|endoplasmic reticulum unfolded protein response, ! heme metabolic process GO:0042168 36 19 0,000 0,0991455 0,12621379 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,0991455 0,12614705 ! plasma membrane fusion GO:0045026 28 19 0,000 0,0991455 0,12608037 ! peptide cross-linking GO:0018149 37 19 0,000 0,0991455 0,12601377 ! protein export from nucleus GO:0006611 36 19 0,000 0,0991455 0,12594723 ! heart process GO:0003015 30 19 0,000 0,0991455 0,12588077 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,0991455 0,12581438 GO:0006692|prostanoid metabolic process, ! visual learning GO:0008542 36 19 0,000 0,0991455 0,12574806 ! cellular pigmentation GO:0033059 36 19 0,000 0,0991455 0,1256818 ! G1 phase GO:0051318 40 19 0,000 0,0991455 0,12561562 ! cell-cell junction organization GO:0045216 35 19 0,000 0,0991455 0,12554951 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,0991455 0,12548346 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,0991455 0,12541749 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,0991455 0,12535158 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,0991455 0,12528575 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,0991455 0,12521998 ! cilium assembly GO:0042384 37 19 0,000 0,0991455 0,12515428 ! peptide hormone secretion GO:0030072 31 19 0,000 0,0991455 0,12508865 ! hormone metabolic process GO:0042445 157 97 1,000 0,09923668 0,12513807 ! response to virus GO:0009615 160 98 1,000 0,10095401 0,12723696 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,10408406 0,13111322 ! positive regulation of ossification GO:0045778 47 20 0,000 0,10408406 0,13104461 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,10408406 0,13097607 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,10408406 0,13090761 ! cAMP metabolic process GO:0046058 36 20 0,000 0,10408406 0,13083921 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,10408406 0,13077089 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,10408406 0,13070264 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,10408406 0,13063446 ! response to alkaloid GO:0043279 38 20 0,000 0,10408406 0,13056635 ! pancreas development GO:0031016 35 20 0,000 0,10408406 0,13049831 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,10408406 0,13043034 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,10408406 0,13036244 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,10408406 0,13029462 GO:0032392|DNA geometric change, ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,10408406 0,13022686 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,10408406 0,13015918 ! body fluid secretion GO:0007589 31 20 0,000 0,10408406 0,13009156 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,10408406 0,13002402 ! peptide secretion GO:0002790 35 20 0,000 0,10408406 0,12995654 ! stem cell differentiation GO:0048863 53 20 0,000 0,10408406 0,12988914 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,10408406 0,1298218 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,10408406 0,12975454 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,10408406 0,12968734 ! sensory perception of pain GO:0019233 30 20 0,000 0,10408406 0,12962021 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,10408406 0,12955316 ! diencephalon development GO:0021536 34 20 0,000 0,10408406 0,12948617 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,10408406 0,12941925 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,10408406 0,1293524 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,10408406 0,12928562 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,10408406 0,12921891 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,10408406 0,12915227 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,10408406 0,1290857 GO:0043450|alkene biosynthetic process, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,10408406 0,12901919 ! actin filament-based movement GO:0030048 43 20 0,000 0,10408406 0,12895276 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,10408406 0,12888639 ! negative regulation of translation GO:0017148 29 20 0,000 0,10408406 0,12882009 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,10408406 0,12875386 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,10899572 0,13476038 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,10899572 0,13469117 ! hormone secretion GO:0046879 38 21 0,000 0,10899572 0,13462202 ! glycerol metabolic process GO:0006071 34 21 0,000 0,10899572 0,13455295 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,10899572 0,13448395 ! axis specification GO:0009798 38 21 0,000 0,10899572 0,13441502 ! ovarian follicle development GO:0001541 35 21 0,000 0,10899572 0,13434616 ! smooth muscle contraction GO:0006939 46 21 0,000 0,10899572 0,13427737 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,10899572 0,13420865 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,10899572 0,13414 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,10899572 0,13407142 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,10899572 0,13400291 ! cytolysis GO:0019835 24 21 0,000 0,10899572 0,13393447 ! vasodilation GO:0042311 39 21 0,000 0,10899572 0,13386611 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,10899572 0,13379781 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,10899572 0,13372958 ! DNA modification GO:0006304 34 21 0,000 0,10899572 0,13366142 ! collagen fibril organization GO:0030199 59 21 0,000 0,10899572 0,13359333 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,10899572 0,13352531 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,10899572 0,13345735 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,10899572 0,13338947 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,10899572 0,13332166 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,10899572 0,13325391 ! collagen catabolic process GO:0030574 28 21 0,000 0,10899572 0,13318624 ! sperm-egg recognition GO:0035036 21 21 0,000 0,10899572 0,13311863 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,11388061 0,13901408 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,11388061 0,13894359 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,11388061 0,13887316 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,11388061 0,13880281 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,11388061 0,13873253 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,11388061 0,13866232 ! regeneration GO:0031099 41 22 0,000 0,11388061 0,13859219 ! keratinization GO:0031424 28 22 0,000 0,11388061 0,13852212 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,11388061 0,13845212 ! sensory perception of taste GO:0050909 28 22 0,000 0,11388061 0,1383822 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,11388061 0,13831234 ! vacuolar transport GO:0007034 36 22 0,000 0,11388061 0,13824256 ! lysosome organization GO:0007040 41 22 0,000 0,11388061 0,13817284 ! central nervous system neuron development GO:0021954 46 22 0,000 0,11388061 0,1381032 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,11388061 0,13803363 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,11388061 0,13796412 ! fucose metabolic process GO:0006004 39 22 0,000 0,11388061 0,13789469 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,11388061 0,13782533 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,11388061 0,13775603 GO:0060415|muscle tissue morphogenesis, ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,11388061 0,13768681 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,11388061 0,13761765 ! sarcomere organization GO:0045214 30 22 0,000 0,11388061 0,13754857 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,11388061 0,13747955 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,11388061 0,13741061 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,11388061 0,13734173 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,11388061 0,13727292 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,11388061 0,13720418 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,11873888 0,14298586 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,11873888 0,14291433 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,11873888 0,14284288 ! viral genome replication GO:0019079 41 23 0,000 0,11873888 0,14277149 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,11873888 0,14270018 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,11873888 0,14262893 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,11873888 0,14255776 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,11873888 0,14248666 GO:0006044|N-acetylglucosamine metabolic process, ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,11873888 0,14241563 ! visual behavior GO:0007632 42 23 0,000 0,11873888 0,14234467 ! response to ethanol GO:0045471 46 23 0,000 0,11873888 0,14227378 ! peroxisome organization GO:0007031 37 23 0,000 0,11873888 0,14220296 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,11873888 0,14213222 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,11873888 0,14206154 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,11873888 0,14199093 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,11873888 0,14192039 GO:0051693|actin filament capping, ! regulation of viral reproduction GO:0050792 38 23 0,000 0,11873888 0,14184993 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,11873888 0,14177953 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,11873888 0,1417092 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,11873888 0,14163895 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,11873888 0,14156876 ! fatty acid transport GO:0015908 44 23 0,000 0,11873888 0,14149864 ! platelet activation GO:0030168 37 23 0,000 0,11873888 0,14142859 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,11873888 0,14135861 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,11873888 0,1412887 ! hormone transport GO:0009914 40 23 0,000 0,11873888 0,14121886 ! cell-cell recognition GO:0009988 25 23 0,000 0,11873888 0,14114909 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,11873888 0,14107938 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,11873888 0,14100975 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,11873888 0,14094018 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,11873888 0,14087069 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,12357068 0,14653083 GO:0016444|somatic cell DNA recombination, ! vesicle docking GO:0048278 47 24 0,000 0,12357068 0,14645865 ! spinal cord development GO:0021510 47 24 0,000 0,12357068 0,14638654 ! vacuole organization GO:0007033 43 24 0,000 0,12357068 0,1463145 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,12357068 0,14624253 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,12357068 0,14617063 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,12357068 0,1460988 ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,12357068 0,14602704 ! membrane depolarization GO:0051899 39 24 0,000 0,12357068 0,14595535 ! pallium development GO:0021543 49 24 0,000 0,12357068 0,14588374 ! pentose metabolic process GO:0019321 35 24 0,000 0,12357068 0,14581219 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,12357068 0,14574071 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,12357068 0,14566931 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,12357068 0,14559797 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,12357068 0,1455267 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,12357068 0,14545551 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,12357068 0,14538438 ! regulation of amine transport GO:0051952 40 24 0,000 0,12357068 0,14531332 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,12837614 0,15089057 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,12837614 0,1508169 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,12837614 0,15074329 ! phototransduction GO:0007602 33 25 0,000 0,12837614 0,15066976 ! sperm motility GO:0030317 31 25 0,000 0,12837614 0,1505963 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,12837614 0,15052291 ! chromosome condensation GO:0030261 45 25 0,000 0,12837614 0,15044959 ! osteoblast differentiation GO:0001649 60 25 0,000 0,12837614 0,15037634 ! coenzyme catabolic process GO:0009109 39 25 0,000 0,12837614 0,15030316 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,12837614 0,15023006 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,12837614 0,15015703 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,12837614 0,15008406 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,12837614 0,15001117 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,12837614 0,14993835 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,12837614 0,1498656 ! telomere organization GO:0032200 43 25 0,000 0,12837614 0,14979292 GO:0000723|telomere maintenance, ! liver development GO:0001889 53 25 0,000 0,12837614 0,14972031 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,13315542 0,15521896 ! embryonic pattern specification GO:0009880 44 26 0,000 0,13315542 0,1551438 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,13315542 0,1550687 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,13315542 0,15499368 ! initiation of viral infection GO:0019059 57 26 0,000 0,13315542 0,15491873 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,13315542 0,15484386 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,13315542 0,15476905 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,13315542 0,15469432 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,13315542 0,15461966 ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,13315542 0,15454507 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,13315542 0,15447056 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,13315542 0,15439611 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,13315542 0,15432174 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,13315542 0,15424744 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,13315542 0,15417321 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,13315542 0,15409906 ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,13315542 0,15402497 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,13315542 0,15395096 ! neuron fate commitment GO:0048663 48 27 0,000 0,13790865 0,15936993 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,13790865 0,15929342 ! iron ion transport GO:0006826 59 27 0,000 0,13790865 0,15921699 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,13790865 0,15914062 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,13790865 0,15906433 ! fat cell differentiation GO:0045444 50 27 0,000 0,13790865 0,15898812 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,13790865 0,15891197 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,13790865 0,1588359 ! autophagy GO:0006914 41 27 0,000 0,13790865 0,15875991 ! male gonad development GO:0008584 44 27 0,000 0,13790865 0,15868398 ! response to toxin GO:0009636 47 27 0,000 0,13790865 0,15860813 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,13790865 0,15853235 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,13790865 0,15845664 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,13790865 0,158381 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,13790865 0,15830544 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,13790865 0,15822995 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,14263597 0,16357585 ! circadian rhythm GO:0007623 50 28 0,000 0,14263597 0,16349792 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,14263597 0,16342006 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,14263597 0,16334228 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,14263597 0,16326457 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,14263597 0,16318694 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,14263597 0,16310938 ! synaptogenesis GO:0007416 42 28 0,000 0,14263597 0,16303189 ! lipid oxidation GO:0034440 43 28 0,000 0,14263597 0,16295448 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,14263597 0,16287714 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,14263597 0,16279987 ! translational initiation GO:0006413 65 29 0,000 0,14733752 0,16808633 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,14733752 0,16800667 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,14733752 0,16792708 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,14733752 0,16784757 ! catechol metabolic process GO:0009712 54 29 0,000 0,14733752 0,16776814 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,14733752 0,16768878 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,14733752 0,16760949 ! cell fate determination GO:0001709 60 29 0,000 0,14733752 0,16753028 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,14733752 0,16745115 ! detection of light stimulus GO:0009583 38 29 0,000 0,14733752 0,16737208 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,14733752 0,1672931 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,14733752 0,16721419 ! regulation of coagulation GO:0050818 46 29 0,000 0,14733752 0,16713535 ! phenol metabolic process GO:0018958 55 30 0,000 0,15201345 0,17235832 ! zinc ion transport GO:0006829 45 30 0,000 0,15201345 0,17227713 ! membrane docking GO:0022406 61 30 0,000 0,15201345 0,17219602 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,15201345 0,17211499 ! regulation of innate immune response GO:0045088 51 30 0,000 0,15201345 0,17203403 ! acute-phase response GO:0006953 49 30 0,000 0,15201345 0,17195315 ! myofibril assembly GO:0030239 47 30 0,000 0,15201345 0,17187235 GO:0055002|striated muscle cell development, ! determination of left/right symmetry GO:0007368 47 30 0,000 0,15201345 0,17179162 ! phospholipid transport GO:0015914 51 30 0,000 0,15201345 0,17171097 ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,15201345 0,17163039 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,15201345 0,17154989 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,15201345 0,17146946 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,15666389 0,17663229 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,15666389 0,17654956 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,15666389 0,17646691 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,15666389 0,17638433 GO:0009799|determination of symmetry, ! inner ear morphogenesis GO:0042472 47 31 0,000 0,15666389 0,17630183 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,15666389 0,17621941 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,15666389 0,17613706 ! ovulation cycle process GO:0022602 49 31 0,000 0,15666389 0,17605479 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,15666389 0,1759726 ! peptide transport GO:0015833 55 31 0,000 0,15666389 0,17589049 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,15666389 0,17580845 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,15666389 0,17572649 ! mesoderm formation GO:0001707 69 31 0,000 0,15666389 0,1756446 ! natural killer cell activation GO:0030101 45 31 0,000 0,15666389 0,17556279 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,15666389 0,17548106 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,15666389 0,1753994 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,16128898 0,18049362 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,16128898 0,18040971 ! cholesterol transport GO:0030301 56 32 0,000 0,16128898 0,18032587 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,16128898 0,18024212 ! spindle organization GO:0007051 46 32 0,000 0,16128898 0,18015844 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,16128898 0,18007484 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,16128898 0,17999132 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,16128898 0,17990787 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,16128898 0,1798245 ! muscle cell development GO:0055001 49 32 0,000 0,16128898 0,17974121 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,16128898 0,179658 ! ovulation cycle GO:0042698 51 32 0,000 0,16128898 0,17957486 ! BMP signaling pathway GO:0030509 64 32 0,000 0,16128898 0,1794918 ! hindbrain development GO:0030902 61 32 0,000 0,16128898 0,17940882 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,16128898 0,17932592 ! gene silencing GO:0016458 65 32 0,000 0,16128898 0,17924309 ! post-embryonic development GO:0009791 69 33 0,000 0,16588886 0,18426989 ! protein targeting to membrane GO:0006612 68 33 0,000 0,16588886 0,18418486 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,16588886 0,1840999 ! ceramide metabolic process GO:0006672 64 33 0,000 0,16588886 0,18401502 ! formation of primary germ layer GO:0001704 72 33 0,000 0,16588886 0,18393022 ! cell fate specification GO:0001708 52 33 0,000 0,16588886 0,1838455 ! sterol transport GO:0015918 57 33 0,000 0,16588886 0,18376086 ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,16588886 0,18367629 ! adult locomotory behavior GO:0008344 59 33 0,000 0,16588886 0,18359181 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,16588886 0,1835074 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,17046366 0,18848142 ! glial cell differentiation GO:0010001 63 34 0,000 0,17046366 0,18839484 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,17046366 0,18830834 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,17046366 0,18822192 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,17046366 0,18813558 ! mismatch repair GO:0006298 46 34 0,000 0,17046366 0,18804932 ! spermatid development GO:0007286 63 34 0,000 0,17046366 0,18796313 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,17046366 0,18787703 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,17046366 0,18779101 ! negative regulation of secretion GO:0051048 63 35 0,000 0,17501352 0,19271512 ! odontogenesis GO:0042476 66 35 0,000 0,17501352 0,19262696 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,17501352 0,19253888 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,17501352 0,19245088 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,17501352 0,19236296 ! cytokine production GO:0001816 59 35 0,000 0,17501352 0,19227513 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,17501352 0,19218737 ! vesicle localization GO:0051648 64 35 0,000 0,17501352 0,19209969 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,17953858 0,19697666 ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,17953858 0,19688688 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,17953858 0,19679718 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,17953858 0,19670757 ! positive regulation of cell development GO:0010720 80 36 0,000 0,17953858 0,19661803 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,17953858 0,19652858 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,17953858 0,19643921 ! aerobic respiration GO:0009060 55 36 0,000 0,17953858 0,19634992 ! androgen receptor signaling pathway GO:0030521 74 36 0,000 0,17953858 0,19626071 ! RNA export from nucleus GO:0006405 56 37 0,000 0,18403896 0,20108889 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,18403896 0,20099762 ! meiosis I GO:0007127 65 37 0,000 0,18403896 0,20090642 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,18403896 0,2008153 ! sister chromatid segregation GO:0000819 58 37 0,000 0,18403896 0,20072427 ! actomyosin structure organization GO:0031032 62 37 0,000 0,18403896 0,20063332 ! organic anion transport GO:0015711 68 37 0,000 0,18403896 0,20054246 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,18403896 0,20045167 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,18403896 0,20036097 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,18403896 0,20027035 GO:0015986|ATP synthesis coupled proton transport, ! pigment metabolic process GO:0042440 80 37 0,000 0,18403896 0,20017981 ! spermatid differentiation GO:0048515 66 37 0,000 0,18403896 0,20008936 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,18851481 0,20486298 GO:0006956|complement activation, ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,18851481 0,20477049 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,18851481 0,20467809 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,18851481 0,20458577 ! lipid homeostasis GO:0055088 67 38 0,000 0,18851481 0,20449353 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,18851481 0,20440137 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,18851481 0,2043093 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,18851481 0,20421731 ! mRNA catabolic process GO:0006402 71 39 0,000 0,19296626 0,20894546 ! ear morphogenesis GO:0042471 60 39 0,000 0,19296626 0,20885147 ! organic ether metabolic process GO:0018904 55 39 0,000 0,19296626 0,20875756 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,19296626 0,20866374 ! ion transmembrane transport GO:0034220 66 39 0,000 0,19296626 0,20857 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,19296626 0,20847635 ! RNA modification GO:0009451 57 39 0,000 0,19296626 0,20838277 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,19739343 0,21306801 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,19739343 0,21297247 ! feeding behavior GO:0007631 59 40 0,000 0,19739343 0,21287701 ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,19739343 0,21278163 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,20179647 0,2174305 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,20179647 0,21733317 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,20179647 0,21723593 ! gliogenesis GO:0042063 88 41 0,000 0,20179647 0,21713878 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,20179647 0,21704171 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,20179647 0,21694473 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,20179647 0,21684784 ! response to reactive oxygen species GO:0000302 67 42 0,000 0,2061755 0,22145457 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,2061755 0,22135575 ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,2061755 0,22125702 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,2061755 0,22115838 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,21053064 0,22572938 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,21053064 0,22562883 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,21053064 0,22552837 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,21053064 0,225428 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,21053064 0,22532773 ! striated muscle contraction GO:0006941 77 43 0,000 0,21053064 0,22522753 ! phagocytosis GO:0006909 90 43 0,000 0,21053064 0,22512743 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,21053064 0,22502742 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,21486204 0,22955509 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,21486204 0,2294532 ! male sex differentiation GO:0046661 76 44 0,000 0,21486204 0,22935141 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,21486204 0,2292497 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,21916982 0,23374228 ! glycolysis GO:0006096 65 45 0,000 0,21916982 0,23363871 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,21916982 0,23353524 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,21916982 0,23343186 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,21916982 0,23332857 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,21916982 0,23322538 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,21916982 0,23312227 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,21916982 0,23301926 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,21916982 0,23291633 ! cell growth GO:0016049 84 45 0,000 0,21916982 0,2328135 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,2234541 0,23725974 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,2234541 0,23715508 ! pigmentation GO:0043473 100 46 0,000 0,2234541 0,23705051 ! response to calcium ion GO:0051592 81 47 0,000 0,22771502 0,24146423 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,22771502 0,24135786 ! JNK cascade GO:0007254 91 47 0,000 0,22771502 0,24125158 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,22771502 0,24114539 ! Notch signaling pathway GO:0007219 96 48 0,000 0,2319527 0,24552494 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,2319527 0,24541697 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,2319527 0,2453091 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,23616726 0,24965661 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,23616726 0,24954696 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,23616726 0,24943742 ! regulation of ion transport GO:0043269 77 49 0,000 0,23616726 0,24932797 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,23616726 0,24921861 ! endocrine system development GO:0035270 104 49 0,000 0,23616726 0,24910935 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,23616726 0,24900019 GO:0019724|B cell mediated immunity, ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,23616726 0,24889113 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,24035884 0,25319763 ! neuromuscular process GO:0050905 99 50 0,000 0,24035884 0,25308682 ! regulation of ossification GO:0030278 117 50 0,000 0,24035884 0,25297611 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,24035884 0,25286549 ! viral infectious cycle GO:0019058 99 51 0,000 0,24452756 0,25713868 ! excretion GO:0007588 83 51 0,000 0,24452756 0,25702635 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,24452756 0,25691411 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,24452756 0,25680197 ! vesicle organization GO:0016050 107 51 0,000 0,24452756 0,25668993 ! membrane fusion GO:0006944 110 52 0,000 0,24867354 0,26092827 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,24867354 0,26081453 ! amino acid activation GO:0043038 92 52 0,000 0,24867354 0,26070088 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 76 53 0,000 0,2527969 0,26490825 ! RNA catabolic process GO:0006401 93 53 0,000 0,2527969 0,26479292 ! regulation of translational initiation GO:0006446 82 53 0,000 0,2527969 0,26467769 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,2527969 0,26456257 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,2527969 0,26444754 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,2527969 0,26433261 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,2527969 0,26421778 ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,25689777 0,26838733 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,25689777 0,26827085 ! cell recognition GO:0008037 85 54 0,000 0,25689777 0,26815446 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,25689777 0,26803817 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,25689777 0,26792199 ! chloride transport GO:0006821 90 55 0,000 0,26097626 0,27205758 ! glucose catabolic process GO:0006007 82 55 0,000 0,26097626 0,27193975 ! gastrulation GO:0007369 112 55 0,000 0,26097626 0,27182203 ! RNA elongation GO:0006354 79 55 0,000 0,26097626 0,27170441 ! nuclear export GO:0051168 97 55 0,000 0,26097626 0,27158689 ! regulation of actin filament length GO:0030832 105 56 0,000 0,26503251 0,27568881 ! sensory perception of smell GO:0007608 80 56 0,000 0,26503251 0,27556967 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,26503251 0,27545064 ! proton transport GO:0015992 94 56 0,000 0,26503251 0,2753317 ! positive regulation of organelle organization GO:0010638 100 56 0,000 0,26503251 0,27521287 ! hydrogen transport GO:0006818 97 58 0,000 0,27307874 0,28344584 ! adult behavior GO:0030534 99 58 0,000 0,27307874 0,28332361 ! regulation of cellular component size GO:0032535 109 59 0,000 0,27706896 0,28733962 ! establishment of organelle localization GO:0051656 109 59 0,000 0,27706896 0,28721582 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,28103741 0,29120414 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,28103741 0,29107878 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,2849842 0,29503958 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,2849842 0,29491269 ! mesoderm development GO:0007498 119 61 0,000 0,2849842 0,2947859 ! tRNA processing GO:0008033 89 61 0,000 0,2849842 0,29465922 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,2849842 0,29453264 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,28890946 0,29846121 ! regulation of mitosis GO:0007088 105 63 0,000 0,2928133 0,3023643 GO:0051783|regulation of nuclear division, ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,2928133 0,30223458 ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,2928133 0,30210498 ! detection of external stimulus GO:0009581 91 63 0,000 0,2928133 0,30197549 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,2928133 0,30184611 ! steroid hormone receptor signaling pathway GO:0030518 129 63 0,000 0,2928133 0,30171683 ! cell redox homeostasis GO:0045454 102 64 0,000 0,29669584 0,30558656 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,29669584 0,3054558 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,29669584 0,30532515 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,29669584 0,30519461 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,30055719 0,30903445 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,30055719 0,30890244 ! myeloid cell differentiation GO:0030099 111 65 0,000 0,30055719 0,30877054 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,30439747 0,3125823 ! extracellular matrix organization GO:0030198 133 66 0,000 0,30439747 0,31244894 ! hexose catabolic process GO:0019320 104 67 0,000 0,30821679 0,31623437 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,31201527 0,3199952 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 0,000 0,31201527 0,31985886 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,31201527 0,31972263 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,31579302 0,32345594 ! antigen processing and presentation GO:0019882 104 69 0,000 0,31579302 0,3233183 ! amine catabolic process GO:0009310 117 71 0,000 0,32328676 0,33084983 ! humoral immune response GO:0006959 109 71 0,000 0,32328676 0,33070916 ! acute inflammatory response GO:0002526 113 72 0,000 0,32700299 0,33436855 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,33069893 0,33800409 ! fertilization GO:0009566 90 73 0,000 0,33069893 0,33786056 ! transition metal ion transport GO:0000041 126 74 0,000 0,33437469 0,34147093 ! neurotransmitter transport GO:0006836 123 74 0,000 0,33437469 0,34132605 ! exocytosis GO:0006887 133 74 0,000 0,33437469 0,3411813 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,33437469 0,34103667 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,33437469 0,34089217 ! organelle localization GO:0051640 136 74 0,000 0,33437469 0,34074778 ! rhythmic process GO:0048511 128 75 0,000 0,33803039 0,34432732 ! defense response to bacterium GO:0042742 89 76 0,000 0,34166613 0,3478835 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,34166613 0,34773634 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,34166613 0,34758931 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,34528203 0,35111943 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,34528203 0,35097109 ! blood coagulation GO:0007596 146 78 0,000 0,34887818 0,35447673 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,34887818 0,3543271 ! negative regulation of organelle organization GO:0010639 161 78 0,000 0,34887818 0,3541776 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,3524547 0,35765754 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,3524547 0,35750675 ! response to metal ion GO:0010038 140 80 0,000 0,3560117 0,36096256 ! muscle cell differentiation GO:0042692 159 80 0,000 0,3560117 0,36081051 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,3560117 0,36065859 ! inorganic anion transport GO:0015698 138 80 0,000 0,3560117 0,36050679 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,35954927 0,36393586 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,35954927 0,36378282 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,36306753 0,36718809 ! hemostasis GO:0007599 158 84 0,000 0,37004651 0,37408904 ! response to unfolded protein GO:0006986 131 85 0,000 0,37350745 0,3774292 ! nucleosome assembly GO:0006334 122 85 0,000 0,37350745 0,37727075 ! response to inorganic substance GO:0010035 153 86 0,000 0,37694949 0,38058769 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,37694949 0,38042805 ! chromatin assembly GO:0031497 124 86 0,000 0,37694949 0,38026854 ! alcohol catabolic process GO:0046164 130 86 0,000 0,37694949 0,38010916 ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,38037273 0,38340041 ! cellular respiration GO:0045333 135 88 0,000 0,38377727 0,38667007 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,38377727 0,38650821 ! cellular defense response GO:0006968 114 89 0,000 0,38716323 0,38975511 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,39053068 0,39298069 ! sterol metabolic process GO:0016125 152 91 0,000 0,39387975 0,39618507 ! response to protein stimulus GO:0051789 149 91 0,000 0,39387975 0,39601951 ! nucleosome organization GO:0034728 138 92 0,000 0,39721053 0,39920156 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,39721053 0,39903488 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,4038176 0,40550298 ! female pregnancy GO:0007565 164 94 0,000 0,4038176 0,40533381 ! transcription initiation GO:0006352 153 94 0,000 0,4038176 0,40516478 ! forebrain development GO:0030900 188 95 0,000 0,40709409 0,40828194 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,40709409 0,40811182 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,41035268 0,41120723 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,41035268 0,41103603 ! detection of stimulus GO:0051606 151 96 0,000 0,41035268 0,41086498 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,41359347 0,41393756 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,41681656 0,41698987 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,41681656 0,41681656 GO:0016054|organic acid catabolic process,