pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6827-VanDeVijver-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/vantveer-oligo_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! membrane fusion GO:0006944 31 31 4,000 1,595E-06 2,94E-03 ! positive regulation of epithelial cell proliferation GO:0050679 14 14 3,000 1,668E-06 1,537E-03 ! amyloid precursor protein catabolic process GO:0042987 5 5 2,000 2,772E-06 1,703E-03 ! regulation of lipid kinase activity GO:0043550 6 6 2,000 5,518E-06 2,542E-03 ! amyloid precursor protein metabolic process GO:0042982 7 7 2,000 9,611E-06 3,542E-03 ! membrane protein ectodomain proteolysis GO:0006509 7 7 2,000 9,611E-06 2,952E-03 GO:0033619|membrane protein proteolysis, ! platelet activation GO:0030168 8 7 2,000 9,611E-06 2,53E-03 ! plasma membrane fusion GO:0045026 8 8 2,000 1,53E-05 3,526E-03 ! positive regulation of leukocyte migration GO:0002687 8 8 2,000 1,53E-05 3,134E-03 ! regulation of leukocyte migration GO:0002685 9 9 2,000 2,285E-05 4,211E-03 ! protein amino acid autophosphorylation GO:0046777 28 28 3,000 3,185E-05 5,337E-03 ! blood vessel development GO:0001568 95 94 5,000 3,341E-05 5,131E-03 ! regulation of protein localization GO:0032880 58 57 4,000 3,454E-05 4,896E-03 ! regulation of epithelial cell proliferation GO:0050678 29 29 3,000 3,677E-05 4,84E-03 ! vasculature development GO:0001944 97 96 5,000 3,766E-05 4,627E-03 ! establishment of organelle localization GO:0051656 31 30 3,000 4,222E-05 4,863E-03 ! glycoprotein catabolic process GO:0006516 13 12 2,000 5,901E-05 6,397E-03 ! regulation of angiogenesis GO:0045765 35 34 3,000 7,006E-05 7,173E-03 ! regulation of bone remodeling GO:0046850 34 34 3,000 7,006E-05 6,796E-03 ! positive regulation of smooth muscle cell proliferation GO:0048661 13 13 2,000 7,635E-05 7,036E-03 ! vasculogenesis GO:0001570 13 13 2,000 7,635E-05 6,701E-03 ! positive regulation of locomotion GO:0040017 13 13 2,000 7,635E-05 6,396E-03 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, GO:0050920|regulation of chemotaxis, ! regulation of tissue remodeling GO:0034103 35 35 3,000 7,871E-05 6,307E-03 ! positive regulation of cell migration GO:0030335 36 36 3,000 8,812E-05 6,767E-03 ! regulation of behavior GO:0050795 14 14 2,000 9,672E-05 7,13E-03 ! positive regulation of osteoblast differentiation GO:0045669 14 14 2,000 9,672E-05 6,856E-03 ! regulation of transcription factor activity GO:0051090 38 37 3,000 9,832E-05 6,711E-03 GO:0090046|regulation of transcription regulator activity, ! regulation of cell migration GO:0030334 71 71 4,000 1,002E-04 6,593E-03 ! chromosome segregation GO:0007059 38 38 3,000 1,094E-04 6,95E-03 ! positive regulation of cell motion GO:0051272 39 39 3,000 1,213E-04 7,449E-03 ! organelle localization GO:0051640 41 40 3,000 1,341E-04 7,971E-03 ! cell morphogenesis involved in differentiation GO:0000904 82 77 4,000 1,475E-04 8,497E-03 ! regulation of locomotion GO:0040012 79 79 4,000 1,666E-04 9,306E-03 ! regulation of cell motion GO:0051270 79 79 4,000 1,666E-04 9,032E-03 ! neuron projection development GO:0031175 85 80 4,000 1,769E-04 9,313E-03 ! regulation of smooth muscle cell proliferation GO:0048660 17 17 2,000 1,782E-04 9,121E-03 ! myelination GO:0042552 17 17 2,000 1,782E-04 8,874E-03 ! cell junction assembly GO:0034329 18 17 2,000 1,782E-04 8,641E-03 ! regulation of osteoblast differentiation GO:0045667 17 17 2,000 1,782E-04 8,419E-03 ! blood vessel morphogenesis GO:0048514 84 83 4,000 2,104E-04 9,696E-03 ! meiosis I GO:0007127 18 18 2,000 2,128E-04 9,565E-03 ! ensheathment of neurons GO:0007272 18 18 2,000 2,128E-04 9,338E-03 GO:0008366|axon ensheathment, ! regulation of DNA binding GO:0051101 47 45 3,000 2,133E-04 9,143E-03 ! positive regulation of cell differentiation GO:0045597 87 85 4,000 2,354E-04 9,86E-03 ! regulation of anatomical structure morphogenesis GO:0022603 90 86 4,000 2,487E-04 0,01018492 ! placenta development GO:0001890 19 19 2,000 2,515E-04 0,01007685 ! positive regulation of transferase activity GO:0051347 91 88 4,000 2,77E-04 0,01086086 GO:0033674|positive regulation of kinase activity, ! establishment or maintenance of cell polarity GO:0007163 21 20 2,000 2,945E-04 0,01130804 ! ossification GO:0001503 50 49 3,000 2,975E-04 0,01118871 GO:0060348|bone development, ! regulation of DNA metabolic process GO:0051052 51 50 3,000 3,218E-04 0,01186041 ! G1/S transition of mitotic cell cycle GO:0000082 21 21 2,000 3,42E-04 0,01235865 ! Notch signaling pathway GO:0007219 22 21 2,000 3,42E-04 0,01212098 ! regulation of action potential in neuron GO:0019228 21 21 2,000 3,42E-04 0,01189228 ! positive regulation of transcription factor activity GO:0051091 22 22 2,000 3,941E-04 0,01345186 GO:0090047|positive regulation of transcription regulator activity, ! cell junction organization GO:0034330 23 22 2,000 3,941E-04 0,01320728 ! regulation of protein transport GO:0051223 53 53 3,000 4,032E-04 0,01326908 GO:0070201|regulation of establishment of protein localization, ! filopodium assembly GO:0046847 7 5 1,000 4,318E-04 0,01396179 GO:0030035|microspike assembly, ! mRNA stabilization GO:0048255 5 5 1,000 4,318E-04 0,01372107 GO:0043489|RNA stabilization, ! endocrine pancreas development GO:0031018 5 5 1,000 4,318E-04 0,01348851 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 5 5 1,000 4,318E-04 0,0132637 GO:0033135|regulation of peptidyl-serine phosphorylation, ! vesicle fusion GO:0006906 5 5 1,000 4,318E-04 0,01304626 ! regulation of phospholipase A2 activity GO:0032429 5 5 1,000 4,318E-04 0,01283584 ! regulation of vascular endothelial growth factor production GO:0010574 5 5 1,000 4,318E-04 0,01263209 ! enucleate erythrocyte differentiation GO:0043353 6 5 1,000 4,318E-04 0,01243472 ! decidualization GO:0046697 5 5 1,000 4,318E-04 0,01224341 ! positive regulation of interleukin-6 production GO:0032755 5 5 1,000 4,318E-04 0,01205791 ! peptidyl-lysine modification GO:0018205 5 5 1,000 4,318E-04 0,01187794 ! positive regulation of leukocyte chemotaxis GO:0002690 5 5 1,000 4,318E-04 0,01170326 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper cell differentiation GO:0045624 5 5 1,000 4,318E-04 0,01153365 GO:0045622|regulation of T-helper cell differentiation, ! myeloid cell homeostasis GO:0002262 5 5 1,000 4,318E-04 0,01136888 ! blastocyst formation GO:0001825 5 5 1,000 4,318E-04 0,01120876 ! positive regulation of blood vessel endothelial cell migration GO:0043536 5 5 1,000 4,318E-04 0,01105308 ! nucleus localization GO:0051647 5 5 1,000 4,318E-04 0,01090167 ! cell projection assembly GO:0030031 25 23 2,000 4,511E-04 0,01123592 ! androgen receptor signaling pathway GO:0030521 24 24 2,000 5,132E-04 0,01261066 ! regulation of action potential GO:0001508 24 24 2,000 5,132E-04 0,01244473 ! regulation of binding GO:0051098 60 57 3,000 5,334E-04 0,01276639 ! regulation of intracellular protein transport GO:0033157 25 25 2,000 5,804E-04 0,01371479 ! regulation of T cell proliferation GO:0042129 25 25 2,000 5,804E-04 0,01354119 ! positive regulation of DNA binding GO:0043388 26 25 2,000 5,804E-04 0,01337192 ! N-terminal protein amino acid modification GO:0031365 6 6 1,000 6,45E-04 0,01467467 GO:0018409|peptide or protein amino-terminal blocking, ! cartilage condensation GO:0001502 7 6 1,000 6,45E-04 0,01449571 ! regulation of positive chemotaxis GO:0050926 6 6 1,000 6,45E-04 0,01432106 GO:0050927|positive regulation of positive chemotaxis, ! regulation of chemokine biosynthetic process GO:0045073 6 6 1,000 6,45E-04 0,01415058 ! ER overload response GO:0006983 6 6 1,000 6,45E-04 0,0139841 ! focal adhesion formation GO:0048041 7 6 1,000 6,45E-04 0,01382149 ! negative regulation of T cell proliferation GO:0042130 6 6 1,000 6,45E-04 0,01366262 GO:0070667|negative regulation of mast cell proliferation, ! regulation of vascular permeability GO:0043114 6 6 1,000 6,45E-04 0,01350737 ! peptidyl-serine phosphorylation GO:0018105 6 6 1,000 6,45E-04 0,0133556 ! regulation of bone resorption GO:0045124 6 6 1,000 6,45E-04 0,0132072 ! DNA unwinding during replication GO:0006268 6 6 1,000 6,45E-04 0,01306207 ! regulation of T cell differentiation in the thymus GO:0033081 6 6 1,000 6,45E-04 0,01292009 ! phosphoinositide 3-kinase cascade GO:0014065 6 6 1,000 6,45E-04 0,01278116 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 6 6 1,000 6,45E-04 0,0126452 GO:0043372|positive regulation of CD4-positive, alpha beta T cell differentiation, ! protein sumoylation GO:0016925 6 6 1,000 6,45E-04 0,01251209 ! regulation of T-helper 2 type immune response GO:0002828 6 6 1,000 6,45E-04 0,01238175 ! salivary gland morphogenesis GO:0007435 6 6 1,000 6,45E-04 0,01225411 ! maternal placenta development GO:0001893 6 6 1,000 6,45E-04 0,01212906 ! localization within membrane GO:0051668 6 6 1,000 6,45E-04 0,01200655 ! positive regulation of binding GO:0051099 27 26 2,000 6,531E-04 0,01203641 ! regulation of T cell differentiation GO:0045580 26 26 2,000 6,531E-04 0,01191724 ! regulation of nucleocytoplasmic transport GO:0046822 27 27 2,000 7,313E-04 0,01321349 ! axonogenesis GO:0007409 66 62 3,000 7,351E-04 0,01315358 ! regulation of mast cell proliferation GO:0070666 28 28 2,000 8,152E-04 0,01444678 ! angiogenesis GO:0001525 65 64 3,000 8,292E-04 0,01455384 ! positive regulation of cellular component organization GO:0051130 65 65 3,000 8,792E-04 0,01528723 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 7 7 1,000 8,991E-04 0,01548619 ! regulation of chemokine production GO:0032642 7 7 1,000 8,991E-04 0,0153428 ! double-strand break repair via homologous recombination GO:0000724 7 7 1,000 8,991E-04 0,01520204 GO:0000725|recombinational repair, ! regulation of mRNA processing GO:0050684 7 7 1,000 8,991E-04 0,01506384 ! negative regulation of lymphocyte proliferation GO:0050672 7 7 1,000 8,991E-04 0,01492813 GO:0032945|negative regulation of mononuclear cell proliferation, GO:0070664|negative regulation of leukocyte proliferation, ! NLS-bearing substrate import into nucleus GO:0006607 7 7 1,000 8,991E-04 0,01479485 ! cranial nerve development GO:0021545 7 7 1,000 8,991E-04 0,01466392 ! autonomic nervous system development GO:0048483 7 7 1,000 8,991E-04 0,01453529 ! regulation of macrophage differentiation GO:0045649 8 7 1,000 8,991E-04 0,01440889 ! positive regulation of acute inflammatory response GO:0002675 7 7 1,000 8,991E-04 0,01428468 ! regulation of ATPase activity GO:0043462 7 7 1,000 8,991E-04 0,01416259 ! regulation of mRNA stability GO:0043488 7 7 1,000 8,991E-04 0,01404257 ! negative regulation of T cell activation GO:0050868 7 7 1,000 8,991E-04 0,01392456 ! positive regulation of cell cycle GO:0045787 29 29 2,000 9,051E-04 0,01390006 ! regulation of lymphocyte proliferation GO:0050670 29 29 2,000 9,051E-04 0,01378518 GO:0032944|regulation of mononuclear cell proliferation, GO:0070663|regulation of leukocyte proliferation, ! positive regulation of protein transport GO:0051222 29 29 2,000 9,051E-04 0,01367219 ! cell morphogenesis involved in neuron differentiation GO:0048667 72 67 3,000 9,857E-04 0,01477018 GO:0048812|neuron projection morphogenesis, GO:0048858|cell projection morphogenesis, ! striated muscle tissue development GO:0014706 69 67 3,000 9,857E-04 0,01465107 ! positive regulation of response to external stimulus GO:0032103 30 30 2,000 1,001E-03 0,01475757 ! skeletal system morphogenesis GO:0048705 31 30 2,000 1,001E-03 0,01464045 ! regulation of ossification GO:0030278 30 30 2,000 1,001E-03 0,01452517 ! regulation of intracellular transport GO:0032386 31 31 2,000 1,103E-03 0,01588139 ! cell part morphogenesis GO:0032990 75 70 3,000 1,162E-03 0,0166026 ! wound healing GO:0042060 74 70 3,000 1,162E-03 0,01647489 ! muscle tissue development GO:0060537 72 70 3,000 1,162E-03 0,01634913 ! positive regulation of translation GO:0045727 8 8 1,000 1,194E-03 0,01666637 ! negative regulation of bone remodeling GO:0046851 8 8 1,000 1,194E-03 0,01654106 ! organelle fusion GO:0048284 8 8 1,000 1,194E-03 0,01641762 ! pancreas development GO:0031016 8 8 1,000 1,194E-03 0,01629601 ! DNA duplex unwinding GO:0032508 8 8 1,000 1,194E-03 0,01617619 GO:0032392|DNA geometric change, ! cell-cell junction assembly GO:0007043 8 8 1,000 1,194E-03 0,01605811 ! positive regulation of endothelial cell migration GO:0010595 8 8 1,000 1,194E-03 0,01594175 ! sex determination GO:0007530 8 8 1,000 1,194E-03 0,01582706 ! positive regulation of myeloid leukocyte differentiation GO:0002763 9 8 1,000 1,194E-03 0,01571401 ! salivary gland development GO:0007431 8 8 1,000 1,194E-03 0,01560256 ! peptidyl-serine modification GO:0018209 8 8 1,000 1,194E-03 0,01549269 ! regulation of acute inflammatory response GO:0002673 8 8 1,000 1,194E-03 0,01538434 ! regulation of immunoglobulin production GO:0002637 8 8 1,000 1,194E-03 0,01527751 ! regulation of RNA stability GO:0043487 8 8 1,000 1,194E-03 0,01517215 ! peptide hormone secretion GO:0030072 8 8 1,000 1,194E-03 0,01506823 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 32 32 2,000 1,211E-03 0,01518809 ! regulation of lymphocyte differentiation GO:0045619 32 32 2,000 1,211E-03 0,01508547 ! protein maturation by peptide bond cleavage GO:0051605 32 32 2,000 1,211E-03 0,01498423 ! regulation of protein complex assembly GO:0043254 33 33 2,000 1,326E-03 0,01629644 ! regulation of lipid metabolic process GO:0019216 34 34 2,000 1,448E-03 0,0176724 ! positive regulation of cell projection organization GO:0031346 9 9 1,000 1,528E-03 0,01852954 ! positive regulation of protein complex assembly GO:0031334 9 9 1,000 1,528E-03 0,01840843 ! negative regulation of cell cycle process GO:0010948 9 9 1,000 1,528E-03 0,01828889 ! regulation of nitric-oxide synthase activity GO:0050999 9 9 1,000 1,528E-03 0,0181709 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 9 9 1,000 1,528E-03 0,01805442 ! negative regulation of cytokine biosynthetic process GO:0042036 9 9 1,000 1,528E-03 0,01793942 ! positive regulation of endothelial cell proliferation GO:0001938 9 9 1,000 1,528E-03 0,01782588 ! platelet-derived growth factor receptor signaling pathway GO:0048008 9 9 1,000 1,528E-03 0,01771377 ! peptide secretion GO:0002790 9 9 1,000 1,528E-03 0,01760306 ! positive regulation of alpha-beta T cell differentiation GO:0046638 9 9 1,000 1,528E-03 0,01749372 ! histone acetylation GO:0016573 9 9 1,000 1,528E-03 0,01738574 ! negative regulation of tissue remodeling GO:0034104 9 9 1,000 1,528E-03 0,01727908 ! regulation of blood vessel endothelial cell migration GO:0043535 9 9 1,000 1,528E-03 0,01717372 ! defense response to virus GO:0051607 9 9 1,000 1,528E-03 0,01706963 ! mesoderm development GO:0007498 35 35 2,000 1,576E-03 0,01750064 ! positive regulation of phosphorylation GO:0042327 35 35 2,000 1,576E-03 0,01739585 ! positive regulation of phosphorus metabolic process GO:0010562 36 36 2,000 1,712E-03 0,01877644 GO:0045937|positive regulation of phosphate metabolic process, ! coagulation GO:0050817 39 36 2,000 1,712E-03 0,01866534 GO:0007596|blood coagulation, ! meiosis GO:0007126 37 37 2,000 1,854E-03 0,02009875 GO:0051327|M phase of meiotic cell cycle, ! negative regulation of protein kinase activity GO:0006469 37 37 2,000 1,854E-03 0,01998121 ! lung development GO:0030324 38 37 2,000 1,854E-03 0,01986504 ! positive regulation of anti-apoptosis GO:0045768 10 10 1,000 1,902E-03 0,02026383 GO:0045767|regulation of anti-apoptosis, ! reciprocal meiotic recombination GO:0007131 10 10 1,000 1,902E-03 0,02014737 ! hormone secretion GO:0046879 10 10 1,000 1,902E-03 0,02003224 ! negative regulation of nucleocytoplasmic transport GO:0046823 10 10 1,000 1,902E-03 0,01991842 ! calcium-independent cell-cell adhesion GO:0016338 10 10 1,000 1,902E-03 0,01980589 ! cell-substrate junction assembly GO:0007044 11 10 1,000 1,902E-03 0,01969462 ! exocrine system development GO:0035272 10 10 1,000 1,902E-03 0,01958459 ! neuromuscular junction development GO:0007528 10 10 1,000 1,902E-03 0,01947579 ! regulation of alpha-beta T cell differentiation GO:0046637 10 10 1,000 1,902E-03 0,01936819 ! gland morphogenesis GO:0022612 10 10 1,000 1,902E-03 0,01926177 ! nerve development GO:0021675 10 10 1,000 1,902E-03 0,01915652 ! epithelial to mesenchymal transition GO:0001837 10 10 1,000 1,902E-03 0,0190524 ! negative regulation of homeostatic process GO:0032845 10 10 1,000 1,902E-03 0,01894942 ! negative regulation of kinase activity GO:0033673 38 38 2,000 2,003E-03 0,0198515 ! cell-matrix adhesion GO:0007160 39 38 2,000 2,003E-03 0,01974535 ! meiotic cell cycle GO:0051321 38 38 2,000 2,003E-03 0,01964032 ! axon guidance GO:0007411 39 38 2,000 2,003E-03 0,0195364 ! steroid hormone receptor signaling pathway GO:0030518 38 38 2,000 2,003E-03 0,01943358 ! hemostasis GO:0007599 42 39 2,000 2,16E-03 0,02084531 ! respiratory tube development GO:0030323 40 39 2,000 2,16E-03 0,02073674 ! respiratory system development GO:0060541 40 39 2,000 2,16E-03 0,0206293 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 11 11 1,000 2,315E-03 0,02199208 ! myeloid leukocyte differentiation GO:0002573 12 11 1,000 2,315E-03 0,0218793 ! cellular component assembly involved in morphogenesis GO:0010927 11 11 1,000 2,315E-03 0,02176767 ! protein amino acid acetylation GO:0006473 11 11 1,000 2,315E-03 0,02165717 ! positive regulation of nucleocytoplasmic transport GO:0046824 11 11 1,000 2,315E-03 0,02154779 GO:0032388|positive regulation of intracellular transport, ! positive regulation of nitric oxide biosynthetic process GO:0045429 11 11 1,000 2,315E-03 0,02143951 ! positive regulation of alpha-beta T cell activation GO:0046635 11 11 1,000 2,315E-03 0,02133232 ! regulation of monooxygenase activity GO:0032768 11 11 1,000 2,315E-03 0,02122619 ! negative regulation of angiogenesis GO:0016525 11 11 1,000 2,315E-03 0,02112111 ! hindbrain development GO:0030902 11 11 1,000 2,315E-03 0,02101706 ! negative regulation of lymphocyte activation GO:0051250 11 11 1,000 2,315E-03 0,02091404 ! intracellular receptor-mediated signaling pathway GO:0030522 40 40 2,000 2,325E-03 0,02089873 ! myeloid cell differentiation GO:0030099 42 40 2,000 2,325E-03 0,02079728 ! negative regulation of transferase activity GO:0051348 40 40 2,000 2,325E-03 0,02069681 ! regulation of cellular localization GO:0060341 86 85 3,000 2,386E-03 0,02113844 ! positive regulation of protein kinase activity GO:0045860 89 86 3,000 2,49E-03 0,02195654 ! cell cycle checkpoint GO:0000075 42 41 2,000 2,496E-03 0,02190933 ! cell-substrate adhesion GO:0031589 43 42 2,000 2,676E-03 0,02337358 ! positive regulation of protein catabolic process GO:0045732 12 12 1,000 2,766E-03 0,0240472 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 12 12 1,000 2,766E-03 0,0239343 ! acute-phase response GO:0006953 12 12 1,000 2,766E-03 0,02382246 ! osteoblast differentiation GO:0001649 12 12 1,000 2,766E-03 0,02371165 ! regulation of alpha-beta T cell activation GO:0046634 12 12 1,000 2,766E-03 0,02360188 ! fibroblast growth factor receptor signaling pathway GO:0008543 12 12 1,000 2,766E-03 0,02349311 ! regulation of interleukin-6 production GO:0032675 12 12 1,000 2,766E-03 0,02338535 ! regulation of chromosome organization GO:0033044 12 12 1,000 2,766E-03 0,02327856 ! somitogenesis GO:0001756 13 12 1,000 2,766E-03 0,02317275 ! G1 phase GO:0051318 13 12 1,000 2,766E-03 0,0230679 ! hormone transport GO:0009914 12 12 1,000 2,766E-03 0,02296399 ! regulation of mitotic metaphase/anaphase transition GO:0030071 13 12 1,000 2,766E-03 0,02286101 ! homeostasis of number of cells GO:0048872 44 43 2,000 2,863E-03 0,02355826 ! negative regulation of hormone secretion GO:0046888 13 13 1,000 3,255E-03 0,02666369 ! positive regulation of JAK-STAT cascade GO:0046427 13 13 1,000 3,255E-03 0,02654571 ! regulation of DNA recombination GO:0000018 13 13 1,000 3,255E-03 0,02642877 ! regulation of nitric oxide biosynthetic process GO:0045428 13 13 1,000 3,255E-03 0,02631286 ! response to corticosteroid stimulus GO:0031960 13 13 1,000 3,255E-03 0,02619795 GO:0051384|response to glucocorticoid stimulus, ! actin filament bundle formation GO:0051017 13 13 1,000 3,255E-03 0,02608405 ! regulation of endothelial cell migration GO:0010594 13 13 1,000 3,255E-03 0,02597113 ! response to endoplasmic reticulum stress GO:0034976 13 13 1,000 3,255E-03 0,02585919 ! coenzyme catabolic process GO:0009109 13 13 1,000 3,255E-03 0,0257482 GO:0046356|acetyl-CoA catabolic process, GO:0006099|tricarboxylic acid cycle, ! nucleotide-excision repair, DNA gap filling GO:0006297 13 13 1,000 3,255E-03 0,02563817 ! negative regulation of intracellular transport GO:0032387 13 13 1,000 3,255E-03 0,02552907 ! negative regulation of leukocyte activation GO:0002695 13 13 1,000 3,255E-03 0,02542089 ! cell-cell junction organization GO:0045216 13 13 1,000 3,255E-03 0,02531363 ! blastocyst development GO:0001824 13 13 1,000 3,255E-03 0,02520727 ! tissue homeostasis GO:0001894 13 13 1,000 3,255E-03 0,0251018 GO:0048871|multicellular organismal homeostasis, ! phosphoinositide-mediated signaling GO:0048015 45 45 2,000 3,262E-03 0,02504745 ! Wnt receptor signaling pathway GO:0016055 46 45 2,000 3,262E-03 0,02494352 ! protein processing GO:0016485 45 45 2,000 3,262E-03 0,02484045 ! regulation of membrane potential GO:0042391 46 46 2,000 3,473E-03 0,02634113 ! regulation of cell growth GO:0001558 97 96 3,000 3,71E-03 0,02802573 ! acetyl-CoA metabolic process GO:0006084 14 14 1,000 3,782E-03 0,02844698 ! protein amino acid acylation GO:0043543 14 14 1,000 3,782E-03 0,02833134 ! response to retinoic acid GO:0032526 14 14 1,000 3,782E-03 0,02821664 GO:0033189|response to vitamin A, ! peptide transport GO:0015833 14 14 1,000 3,782E-03 0,02810286 ! base-excision repair GO:0006284 14 14 1,000 3,782E-03 0,02799 ! positive regulation of inflammatory response GO:0050729 14 14 1,000 3,782E-03 0,02787804 ! response to molecule of bacterial origin GO:0002237 14 14 1,000 3,782E-03 0,02776697 ! gland development GO:0048732 51 49 2,000 4,157E-03 0,03040074 ! cell cycle arrest GO:0007050 49 49 2,000 4,157E-03 0,03028058 ! skeletal muscle tissue development GO:0007519 50 49 2,000 4,157E-03 0,03016137 GO:0060538|skeletal muscle organ development, ! positive regulation of MAP kinase activity GO:0043406 50 49 2,000 4,157E-03 0,03004309 ! muscle organ development GO:0007517 102 100 3,000 4,296E-03 0,03092453 ! negative regulation of protein complex assembly GO:0031333 15 15 1,000 4,345E-03 0,03115807 ! response to vitamin GO:0033273 15 15 1,000 4,345E-03 0,0310373 ! striated muscle cell differentiation GO:0051146 16 15 1,000 4,345E-03 0,03091747 ! insulin receptor signaling pathway GO:0008286 17 15 1,000 4,345E-03 0,03079855 ! ER-nuclear signaling pathway GO:0006984 15 15 1,000 4,345E-03 0,03068055 ! regulation of production of molecular mediator of immune response GO:0002700 15 15 1,000 4,345E-03 0,03056345 ! cholesterol biosynthetic process GO:0006695 15 15 1,000 4,345E-03 0,03044724 ! leukocyte homeostasis GO:0001776 15 15 1,000 4,345E-03 0,03033191 ! positive regulation of B cell activation GO:0050871 15 15 1,000 4,345E-03 0,03021745 ! positive regulation of myeloid cell differentiation GO:0045639 16 15 1,000 4,345E-03 0,03010385 ! negative regulation of transcription factor activity GO:0043433 16 15 1,000 4,345E-03 0,0299911 GO:0090048|negative regulation of transcription regulator activity, ! negative regulation of cell activation GO:0050866 15 15 1,000 4,345E-03 0,02987919 ! protein homooligomerization GO:0051260 15 15 1,000 4,345E-03 0,02976812 ! negative regulation of transport GO:0051051 51 50 2,000 4,402E-03 0,03004494 ! anterior/posterior pattern formation GO:0009952 51 50 2,000 4,402E-03 0,02993408 ! protein modification by small protein conjugation GO:0032446 52 51 2,000 4,655E-03 0,03154088 ! interphase of mitotic cell cycle GO:0051329 52 51 2,000 4,655E-03 0,03142535 GO:0051325|interphase, ! protein maturation GO:0051604 51 51 2,000 4,655E-03 0,03131066 ! regulation of body fluid levels GO:0050878 55 52 2,000 4,917E-03 0,03295311 ! vesicle targeting GO:0006903 17 16 1,000 4,945E-03 0,03301724 ! segmentation GO:0035282 17 16 1,000 4,945E-03 0,03289805 ! regulation of myeloid leukocyte differentiation GO:0002761 17 16 1,000 4,945E-03 0,03277971 ! cofactor catabolic process GO:0051187 16 16 1,000 4,945E-03 0,03266222 ! positive regulation of catabolic process GO:0009896 16 16 1,000 4,945E-03 0,03254557 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 16 16 1,000 4,945E-03 0,03242975 ! positive regulation of mitosis GO:0045840 16 16 1,000 4,945E-03 0,03231475 GO:0051785|positive regulation of nuclear division, ! positive regulation of MAPKKK cascade GO:0043410 17 16 1,000 4,945E-03 0,03220056 ! response to hypoxia GO:0001666 53 53 2,000 5,188E-03 0,03366637 ! regulation of T cell activation GO:0050863 53 53 2,000 5,188E-03 0,03354824 ! response to oxygen levels GO:0070482 55 54 2,000 5,468E-03 0,03523321 ! negative regulation of multicellular organismal process GO:0051241 55 54 2,000 5,468E-03 0,03511045 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 17 17 1,000 5,58E-03 0,03570838 ! positive regulation of cell adhesion GO:0045785 17 17 1,000 5,58E-03 0,03558482 ! glucose transport GO:0015758 17 17 1,000 5,58E-03 0,03546211 ! tissue remodeling GO:0048771 17 17 1,000 5,58E-03 0,03534025 ! embryonic skeletal system morphogenesis GO:0048704 17 17 1,000 5,58E-03 0,03521922 ! regulation of oxidoreductase activity GO:0051341 17 17 1,000 5,58E-03 0,03509902 ! positive regulation of protein secretion GO:0050714 17 17 1,000 5,58E-03 0,03497964 ! protein modification by small protein conjugation or removal GO:0070647 56 55 2,000 5,756E-03 0,03596136 ! regulation of cell projection organization GO:0031344 19 18 1,000 6,251E-03 0,03892058 ! epidermal growth factor receptor signaling pathway GO:0007173 18 18 1,000 6,251E-03 0,03878954 ! hexose transport GO:0008645 18 18 1,000 6,251E-03 0,03865937 GO:0015749|monosaccharide transport, ! negative regulation of DNA binding GO:0043392 19 18 1,000 6,251E-03 0,03853007 ! BMP signaling pathway GO:0030509 18 18 1,000 6,251E-03 0,03840164 ! establishment of vesicle localization GO:0051650 19 18 1,000 6,251E-03 0,03827406 ! DNA damage checkpoint GO:0000077 19 19 1,000 6,957E-03 0,04245467 ! regulation of JAK-STAT cascade GO:0046425 19 19 1,000 6,957E-03 0,04231456 ! regulation of endothelial cell proliferation GO:0001936 19 19 1,000 6,957E-03 0,04217536 ! positive regulation of T cell proliferation GO:0042102 19 19 1,000 6,957E-03 0,04203708 ! positive regulation of T cell differentiation GO:0045582 19 19 1,000 6,957E-03 0,04189971 ! peripheral nervous system development GO:0007422 19 19 1,000 6,957E-03 0,04176323 ! dorsal/ventral pattern formation GO:0009953 19 19 1,000 6,957E-03 0,04162763 ! regulation of cell shape GO:0008360 21 19 1,000 6,957E-03 0,04149292 ! vesicle localization GO:0051648 20 19 1,000 6,957E-03 0,04135907 ! peptidyl-amino acid modification GO:0018193 61 59 2,000 7,001E-03 0,04149032 ! regulation of protein amino acid phosphorylation GO:0001932 62 61 2,000 7,679E-03 0,04536249 ! negative regulation of binding GO:0051100 21 20 1,000 7,697E-03 0,04532138 ! single fertilization GO:0007338 21 20 1,000 7,697E-03 0,04517704 ! regulation of B cell activation GO:0050864 20 20 1,000 7,697E-03 0,04503362 ! regulation of cellular component biogenesis GO:0044087 63 62 2,000 8,032E-03 0,04684765 ! regulation of lymphocyte activation GO:0051249 62 62 2,000 8,032E-03 0,04669987 ! negative regulation of cellular component organization GO:0051129 65 63 2,000 8,395E-03 0,0486543 ! mitotic sister chromatid segregation GO:0000070 21 21 1,000 8,471E-03 0,0489419 ! mammary gland development GO:0030879 23 21 1,000 8,471E-03 0,04878895 ! DNA integrity checkpoint GO:0031570 21 21 1,000 8,471E-03 0,04863696 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 21 21 1,000 8,471E-03 0,04848592 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 21 21 1,000 8,471E-03 0,04833581 ! cellular response to insulin stimulus GO:0032869 23 21 1,000 8,471E-03 0,04818662 ! negative regulation of protein transport GO:0051224 21 21 1,000 8,471E-03 0,04803835 ! regulation of response to external stimulus GO:0032101 65 64 2,000 8,767E-03 0,04956391 ! positive regulation of protein metabolic process GO:0051247 64 64 2,000 8,767E-03 0,04941234 ! positive regulation of DNA metabolic process GO:0051054 23 22 1,000 9,279E-03 0,05213741 ! sister chromatid segregation GO:0000819 22 22 1,000 9,279E-03 0,05197894 ! positive regulation of lymphocyte proliferation GO:0050671 22 22 1,000 9,279E-03 0,05182143 GO:0032946|positive regulation of mononuclear cell proliferation, GO:0070665|positive regulation of leukocyte proliferation, GO:0070668|positive regulation of mast cell proliferation, ! embryonic skeletal system development GO:0048706 22 22 1,000 9,279E-03 0,05166487 ! spindle organization GO:0007051 22 22 1,000 9,279E-03 0,05150925 ! cell chemotaxis GO:0060326 23 22 1,000 9,279E-03 0,05135457 GO:0030595|leukocyte chemotaxis, ! erythrocyte differentiation GO:0030218 23 22 1,000 9,279E-03 0,05120081 ! male sex differentiation GO:0046661 22 22 1,000 9,279E-03 0,05104797 ! sterol biosynthetic process GO:0016126 22 22 1,000 9,279E-03 0,05089605 ! regulation of adaptive immune response GO:0002819 22 22 1,000 9,279E-03 0,05074502 ! positive regulation of lymphocyte differentiation GO:0045621 22 22 1,000 9,279E-03 0,05059489 ! aerobic respiration GO:0009060 22 22 1,000 9,279E-03 0,05044564 ! cytokinesis GO:0000910 23 22 1,000 9,279E-03 0,05029727 ! regulation of MAP kinase activity GO:0043405 67 66 2,000 9,54E-03 0,05156138 ! regulation of hormone secretion GO:0046883 23 23 1,000 0,01011967 0,0545338 ! mitotic cell cycle checkpoint GO:0007093 24 23 1,000 0,01011967 0,05437481 ! endocrine system development GO:0035270 23 23 1,000 0,01011967 0,05421674 ! calcium-mediated signaling GO:0019722 23 23 1,000 0,01011967 0,05405959 ! regionalization GO:0003002 70 69 2,000 0,01077231 0,05737965 ! regulation of leukocyte activation GO:0002694 69 69 2,000 0,01077231 0,05721429 ! regulation of mitotic cell cycle GO:0007346 72 69 2,000 0,01077231 0,05704988 ! erythrocyte homeostasis GO:0034101 25 24 1,000 0,01099299 0,05805181 ! fertilization GO:0009566 25 24 1,000 0,01099299 0,05788595 ! glucan metabolic process GO:0044042 25 24 1,000 0,01099299 0,05772103 GO:0006073|cellular glucan metabolic process, GO:0005977|glycogen metabolic process, ! positive regulation of transport GO:0051050 71 70 2,000 0,01120261 0,05865459 ! regulation of cell activation GO:0050865 71 71 2,000 0,01164278 0,06078653 ! negative regulation of secretion GO:0051048 26 25 1,000 0,01189843 0,06194578 ! generation of a signal involved in cell-cell signaling GO:0003001 27 25 1,000 0,01189843 0,06177129 ! negative regulation of immune system process GO:0002683 25 25 1,000 0,01189843 0,06159777 ! positive regulation of cytokine production GO:0001819 25 25 1,000 0,01189843 0,06142523 ! secretion by cell GO:0032940 75 72 2,000 0,01209285 0,06225451 ! positive regulation of defense response GO:0031349 26 26 1,000 0,01283554 0,06589388 ! glycolysis GO:0006096 26 26 1,000 0,01283554 0,06571084 ! transforming growth factor beta receptor signaling pathway GO:0007179 26 26 1,000 0,01283554 0,06552882 ! negative regulation of cell migration GO:0030336 26 26 1,000 0,01283554 0,0653478 ! double-strand break repair GO:0006302 27 26 1,000 0,01283554 0,06516778 ! regulation of protein secretion GO:0050708 26 26 1,000 0,01283554 0,06498875 ! response to insulin stimulus GO:0032868 28 26 1,000 0,01283554 0,06481069 ! synapse organization GO:0050808 26 26 1,000 0,01283554 0,06463362 ! energy reserve metabolic process GO:0006112 28 27 1,000 0,01380388 0,06932031 ! mesenchymal cell development GO:0014031 29 27 1,000 0,01380388 0,06913194 GO:0060485|mesenchyme development, GO:0048762|mesenchymal cell differentiation, ! defense response to bacterium GO:0042742 27 27 1,000 0,01380388 0,06894459 ! carbohydrate transport GO:0008643 28 28 1,000 0,01480301 0,07373499 ! histone modification GO:0016570 28 28 1,000 0,01480301 0,07353624 ! cartilage development GO:0051216 29 28 1,000 0,01480301 0,07333856 ! regulation of protein modification process GO:0031399 79 78 2,000 0,01500303 0,07413025 ! leukocyte migration GO:0050900 30 29 1,000 0,01583249 0,07801945 ! DNA-dependent DNA replication GO:0006261 29 29 1,000 0,01583249 0,0778114 ! covalent chromatin modification GO:0016569 29 29 1,000 0,01583249 0,07760445 ! response to UV GO:0009411 29 29 1,000 0,01583249 0,0773986 ! tube development GO:0035295 83 81 2,000 0,0165943 0,08090817 ! activation of phospholipase C activity GO:0007202 30 30 1,000 0,01689188 0,0821418 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of protein amino acid phosphorylation GO:0001934 30 30 1,000 0,01689188 0,08192564 ! vascular process in circulatory system GO:0003018 31 30 1,000 0,01689188 0,08171061 ! regulation of inflammatory response GO:0050727 30 30 1,000 0,01689188 0,08149671 ! vesicle organization GO:0016050 30 30 1,000 0,01689188 0,08128393 ! skeletal muscle fiber development GO:0048741 31 31 1,000 0,01798077 0,08629835 ! positive regulation of phospholipase activity GO:0010518 31 31 1,000 0,01798077 0,0860742 ! regulation of DNA replication GO:0006275 32 31 1,000 0,01798077 0,08585121 ! regulation of myeloid cell differentiation GO:0045637 32 31 1,000 0,01798077 0,08562937 ! negative regulation of cell motion GO:0051271 31 31 1,000 0,01798077 0,08540868 ! positive regulation of response to stimulus GO:0048584 86 85 2,000 0,01885857 0,08934792 ! negative regulation of cell growth GO:0030308 32 32 1,000 0,01909873 0,09025374 ! muscle fiber development GO:0048747 32 32 1,000 0,01909873 0,09002292 ! glucose catabolic process GO:0006007 32 32 1,000 0,01909873 0,08979327 ! regulation of phospholipase activity GO:0010517 32 32 1,000 0,01909873 0,08956478 ! positive regulation of lipase activity GO:0060193 32 32 1,000 0,01909873 0,08933746 ! heart development GO:0007507 90 87 2,000 0,0200521 0,09355953 ! negative regulation of cell size GO:0045792 33 33 1,000 0,02024534 0,09422261 ! amino acid transport GO:0006865 33 33 1,000 0,02024534 0,09398527 ! activation of protein kinase activity GO:0032147 35 33 1,000 0,02024534 0,09374913 ! muscle cell differentiation GO:0042692 35 34 1,000 0,02142017 0,0989408 ! cellular polysaccharide metabolic process GO:0044264 35 34 1,000 0,02142017 0,09869345 ! regulation of protein catabolic process GO:0042176 35 34 1,000 0,02142017 0,09844733 ! response to peptide hormone stimulus GO:0043434 36 34 1,000 0,02142017 0,09820244 ! negative regulation of cell cycle GO:0045786 92 91 2,000 0,02256236 0,10318219 ! DNA replication GO:0006260 91 91 2,000 0,02256236 0,10292679 ! acute inflammatory response GO:0002526 35 35 1,000 0,02262283 0,10294786 ! regulation of cyclin-dependent protein kinase activity GO:0000079 35 35 1,000 0,02262283 0,10269429 ! regulation of cytokine biosynthetic process GO:0042035 35 35 1,000 0,02262283 0,10244197 ! multicellular organism reproduction GO:0032504 36 35 1,000 0,02262283 0,10219089 GO:0048609|reproductive process in a multicellular organism, ! regulation of cell morphogenesis GO:0022604 38 35 1,000 0,02262283 0,10194103 ! response to steroid hormone stimulus GO:0048545 35 35 1,000 0,02262283 0,10169239 ! regulation of immune effector process GO:0002697 35 35 1,000 0,02262283 0,10144497 ! energy derivation by oxidation of organic compounds GO:0015980 94 92 2,000 0,02321562 0,10385047 ! positive regulation of immune system process GO:0002684 92 92 2,000 0,02321562 0,10359902 ! regulation of mitosis GO:0007088 37 36 1,000 0,02385291 0,10618577 GO:0051783|regulation of nuclear division, ! female pregnancy GO:0007565 37 36 1,000 0,02385291 0,1059299 ! positive regulation of organelle organization GO:0010638 36 36 1,000 0,02385291 0,10567526 ! integrin-mediated signaling pathway GO:0007229 36 36 1,000 0,02385291 0,10542184 ! gonad development GO:0008406 36 36 1,000 0,02385291 0,10516963 ! regulation of lipase activity GO:0060191 36 36 1,000 0,02385291 0,10491863 ! pattern specification process GO:0007389 96 94 2,000 0,02455302 0,10774099 ! negative regulation of growth GO:0045926 37 37 1,000 0,02510999 0,10992331 ! DNA damage response, signal transduction GO:0042770 37 37 1,000 0,02510999 0,10966283 ! regulation of Rho protein signal transduction GO:0035023 37 37 1,000 0,02510999 0,10940358 ! adaptive immune response GO:0002250 37 37 1,000 0,02510999 0,10914555 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! positive regulation of secretion GO:0051047 39 38 1,000 0,02639369 0,11445545 ! exocytosis GO:0006887 40 38 1,000 0,02639369 0,11418677 ! urogenital system development GO:0001655 38 38 1,000 0,02639369 0,11391936 ! hexose catabolic process GO:0019320 38 38 1,000 0,02639369 0,11365319 ! regulation of homeostatic process GO:0032844 38 38 1,000 0,02639369 0,11338827 ! posttranscriptional regulation of gene expression GO:0010608 98 98 2,000 0,02735121 0,11722857 ! glycoprotein metabolic process GO:0009100 99 98 2,000 0,02735121 0,11695658 ! blood circulation GO:0008015 99 98 2,000 0,02735121 0,11668585 GO:0003013|circulatory system process, ! positive regulation of protein modification process GO:0031401 39 39 1,000 0,0277036 0,11791625 ! nucleotide-excision repair GO:0006289 40 39 1,000 0,0277036 0,11764455 ! cytokine-mediated signaling pathway GO:0019221 39 39 1,000 0,0277036 0,1173741 ! regulation of MAPKKK cascade GO:0043408 41 39 1,000 0,0277036 0,11710489 ! positive regulation of T cell activation GO:0050870 39 39 1,000 0,0277036 0,11683692 ! protein oligomerization GO:0051259 39 39 1,000 0,0277036 0,11657017 ! anti-apoptosis GO:0006916 100 99 2,000 0,02807645 0,11786991 ! response to hormone stimulus GO:0009725 102 100 2,000 0,02881194 0,12068273 ! hemopoiesis GO:0030097 104 100 2,000 0,02881194 0,12040907 ! leukocyte mediated immunity GO:0002443 41 41 1,000 0,03040051 0,1267605 ! monosaccharide catabolic process GO:0046365 41 41 1,000 0,03040051 0,12647436 ! development of primary sexual characteristics GO:0045137 42 42 1,000 0,03178674 0,13194359 ! protein ubiquitination GO:0016567 43 42 1,000 0,03178674 0,13164709 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 42 42 1,000 0,03178674 0,13135192 ! rRNA transcription GO:0009303 5 5 0,000 0,03299564 0,13604244 ! positive regulation of protein ubiquitination GO:0031398 5 5 0,000 0,03299564 0,13573878 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 5 5 0,000 0,03299564 0,13543646 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 5 5 0,000 0,03299564 0,13513549 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! neuron fate specification GO:0048665 5 5 0,000 0,03299564 0,13483586 ! hemoglobin biosynthetic process GO:0042541 5 5 0,000 0,03299564 0,13453755 ! reproductive cellular process GO:0048610 5 5 0,000 0,03299564 0,13424056 ! positive regulation of glucose metabolic process GO:0010907 5 5 0,000 0,03299564 0,13394487 ! negative regulation of blood pressure GO:0045776 6 5 0,000 0,03299564 0,13365049 ! prostate gland development GO:0030850 5 5 0,000 0,03299564 0,1333574 ! metencephalon development GO:0022037 5 5 0,000 0,03299564 0,13306558 ! water transport GO:0006833 5 5 0,000 0,03299564 0,13277505 GO:0042044|fluid transport, ! forebrain regionalization GO:0021871 5 5 0,000 0,03299564 0,13248578 ! DNA synthesis during DNA repair GO:0000731 5 5 0,000 0,03299564 0,13219777 ! positive regulation of B cell proliferation GO:0030890 5 5 0,000 0,03299564 0,131911 ! glycerol metabolic process GO:0006071 5 5 0,000 0,03299564 0,13162548 ! regulation of cellular amine metabolic process GO:0033238 5 5 0,000 0,03299564 0,13134119 GO:0042053|regulation of dopamine metabolic process, GO:0042069|regulation of catecholamine metabolic process, ! meiotic prophase I GO:0007128 5 5 0,000 0,03299564 0,13105813 GO:0051324|prophase, ! cell volume homeostasis GO:0006884 5 5 0,000 0,03299564 0,13077628 ! regulation of epidermal growth factor receptor activity GO:0007176 5 5 0,000 0,03299564 0,13049565 GO:0010469|regulation of receptor activity, ! regulation of long-term neuronal synaptic plasticity GO:0048169 5 5 0,000 0,03299564 0,13021621 ! CTP metabolic process GO:0046036 5 5 0,000 0,03299564 0,12993797 GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0006241|CTP biosynthetic process, ! Golgi to endosome transport GO:0006895 5 5 0,000 0,03299564 0,12966092 ! GTP metabolic process GO:0046039 5 5 0,000 0,03299564 0,12938505 ! establishment of tissue polarity GO:0007164 5 5 0,000 0,03299564 0,12911034 ! positive regulation of cell-cell adhesion GO:0022409 5 5 0,000 0,03299564 0,12883681 ! regulation of neurotransmitter secretion GO:0046928 5 5 0,000 0,03299564 0,12856442 GO:0001956|positive regulation of neurotransmitter secretion, ! neurotransmitter uptake GO:0001504 5 5 0,000 0,03299564 0,12829319 ! social behavior GO:0035176 5 5 0,000 0,03299564 0,1280231 ! macrophage chemotaxis GO:0048246 6 5 0,000 0,03299564 0,12775414 ! 2-oxoglutarate metabolic process GO:0006103 5 5 0,000 0,03299564 0,12748631 ! memory GO:0007613 5 5 0,000 0,03299564 0,12721961 ! dopamine receptor signaling pathway GO:0007212 5 5 0,000 0,03299564 0,12695401 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 5 5 0,000 0,03299564 0,12668953 ! membrane hyperpolarization GO:0060081 5 5 0,000 0,03299564 0,12642614 ! response to lipid GO:0033993 5 5 0,000 0,03299564 0,12616384 ! erythrocyte maturation GO:0043249 5 5 0,000 0,03299564 0,12590263 ! hippocampus development GO:0021766 6 5 0,000 0,03299564 0,1256425 ! regulation of carbohydrate biosynthetic process GO:0043255 5 5 0,000 0,03299564 0,12538345 ! glucocorticoid metabolic process GO:0008211 5 5 0,000 0,03299564 0,12512546 ! middle ear morphogenesis GO:0042474 5 5 0,000 0,03299564 0,12486853 ! mechanosensory behavior GO:0007638 5 5 0,000 0,03299564 0,12461265 ! heart looping GO:0001947 5 5 0,000 0,03299564 0,12435782 ! negative regulation of endocytosis GO:0045806 5 5 0,000 0,03299564 0,12410402 ! response to interferon-gamma GO:0034341 5 5 0,000 0,03299564 0,12385127 ! pseudouridine synthesis GO:0001522 5 5 0,000 0,03299564 0,12359954 ! pH reduction GO:0045851 5 5 0,000 0,03299564 0,12334883 GO:0051452|intracellular pH reduction, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 5 5 0,000 0,03299564 0,12309913 ! lipopolysaccharide metabolic process GO:0008653 5 5 0,000 0,03299564 0,12285045 ! positive regulation of chemokine biosynthetic process GO:0045080 5 5 0,000 0,03299564 0,12260277 ! sphingoid biosynthetic process GO:0046520 5 5 0,000 0,03299564 0,12235608 GO:0046513|ceramide biosynthetic process, ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 5 5 0,000 0,03299564 0,12211039 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! thymic T cell selection GO:0045061 5 5 0,000 0,03299564 0,12186568 ! insulin-like growth factor receptor signaling pathway GO:0048009 5 5 0,000 0,03299564 0,12162194 ! photoreceptor cell maintenance GO:0045494 5 5 0,000 0,03299564 0,12137919 ! adrenal gland development GO:0030325 5 5 0,000 0,03299564 0,12113739 ! regulation of cardiac muscle hypertrophy GO:0010611 5 5 0,000 0,03299564 0,12089656 GO:0010612|regulation of cardiac muscle adaptation, GO:0014743|regulation of muscle hypertrophy, GO:0043502|regulation of muscle adaptation, ! melanocyte differentiation GO:0030318 5 5 0,000 0,03299564 0,12065669 GO:0050931|pigment cell differentiation, ! ovulation GO:0030728 5 5 0,000 0,03299564 0,12041777 ! astrocyte differentiation GO:0048708 5 5 0,000 0,03299564 0,12017979 ! mitochondrial respiratory chain complex assembly GO:0033108 5 5 0,000 0,03299564 0,11994275 GO:0032981|mitochondrial respiratory chain complex I assembly, GO:0010257|NADH dehydrogenase complex assembly, ! pituitary gland development GO:0021983 5 5 0,000 0,03299564 0,11970664 ! tyrosine metabolic process GO:0006570 5 5 0,000 0,03299564 0,11947146 ! cytoskeletal anchoring at plasma membrane GO:0007016 6 5 0,000 0,03299564 0,1192372 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 5 5 0,000 0,03299564 0,11900386 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, GO:0009164|nucleoside catabolic process, ! microtubule nucleation GO:0007020 5 5 0,000 0,03299564 0,11877143 ! regulation of interleukin-6 biosynthetic process GO:0045408 5 5 0,000 0,03299564 0,11853991 ! regulation of interleukin-8 biosynthetic process GO:0045414 5 5 0,000 0,03299564 0,11830928 ! indolalkylamine metabolic process GO:0006586 5 5 0,000 0,03299564 0,11807956 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! muscle cell migration GO:0014812 5 5 0,000 0,03299564 0,11785072 ! phasic smooth muscle contraction GO:0014821 5 5 0,000 0,03299564 0,11762277 ! central nervous system neuron axonogenesis GO:0021955 6 5 0,000 0,03299564 0,1173957 GO:0021952|central nervous system projection neuron axonogenesis, ! sister chromatid cohesion GO:0007062 5 5 0,000 0,03299564 0,1171695 ! response to ATP GO:0033198 5 5 0,000 0,03299564 0,11694418 ! regulation of type I interferon production GO:0032479 5 5 0,000 0,03299564 0,11671972 ! regulation of appetite GO:0032098 5 5 0,000 0,03299564 0,11649612 GO:0032095|regulation of response to food, ! paraxial mesoderm development GO:0048339 5 5 0,000 0,03299564 0,11627337 ! regulation of the force of heart contraction GO:0002026 5 5 0,000 0,03299564 0,11605147 ! maintenance of protein location in nucleus GO:0051457 5 5 0,000 0,03299564 0,11583042 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,03299564 0,11561021 ! receptor clustering GO:0043113 5 5 0,000 0,03299564 0,11539084 ! neurotransmitter biosynthetic process GO:0042136 6 5 0,000 0,03299564 0,1151723 ! fear response GO:0042596 5 5 0,000 0,03299564 0,11495458 ! actin cytoskeleton reorganization GO:0031532 5 5 0,000 0,03299564 0,11473768 ! lens development in camera-type eye GO:0002088 5 5 0,000 0,03299564 0,1145216 ! retinol metabolic process GO:0042572 5 5 0,000 0,03299564 0,11430634 ! corticosteroid receptor signaling pathway GO:0031958 5 5 0,000 0,03299564 0,11409188 GO:0042921|glucocorticoid receptor signaling pathway, ! temperature homeostasis GO:0001659 5 5 0,000 0,03299564 0,11387823 ! positive regulation of exocytosis GO:0045921 6 5 0,000 0,03299564 0,11366537 ! parturition GO:0007567 5 5 0,000 0,03299564 0,11345331 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,03299564 0,11324203 ! Schwann cell differentiation GO:0014037 5 5 0,000 0,03299564 0,11303155 ! acyl-CoA metabolic process GO:0006637 5 5 0,000 0,03299564 0,11282184 ! wound healing, spreading of epidermal cells GO:0035313 5 5 0,000 0,03299564 0,11261291 ! protein heterooligomerization GO:0051291 5 5 0,000 0,03299564 0,11240475 ! regulation of gliogenesis GO:0014013 5 5 0,000 0,03299564 0,11219737 GO:0045685|regulation of glial cell differentiation, ! positive regulation of peptide secretion GO:0002793 5 5 0,000 0,03299564 0,11199074 ! response to UV-B GO:0010224 5 5 0,000 0,03299564 0,11178488 ! oligodendrocyte development GO:0014003 5 5 0,000 0,03299564 0,11157977 ! hyaluronan metabolic process GO:0030212 5 5 0,000 0,03299564 0,11137541 ! activated T cell proliferation GO:0050798 5 5 0,000 0,03299564 0,1111718 ! interaction with symbiont GO:0051702 5 5 0,000 0,03299564 0,11096893 ! cellular extravasation GO:0045123 5 5 0,000 0,03299564 0,1107668 ! positive regulation of axonogenesis GO:0050772 5 5 0,000 0,03299564 0,1105654 ! peptidyl-asparagine modification GO:0018196 5 5 0,000 0,03299564 0,11036474 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! positive regulation of phagocytosis GO:0050766 5 5 0,000 0,03299564 0,1101648 ! regulation of insulin receptor signaling pathway GO:0046626 5 5 0,000 0,03299564 0,10996559 ! antigen processing and presentation of exogenous antigen GO:0019884 5 5 0,000 0,03299564 0,1097671 ! response to amine stimulus GO:0014075 5 5 0,000 0,03299564 0,10956932 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 5 5 0,000 0,03299564 0,10937225 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 5 5 0,000 0,03299564 0,10917589 ! synaptic vesicle exocytosis GO:0016079 6 5 0,000 0,03299564 0,10898024 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 5 5 0,000 0,03299564 0,10878528 ! glycosylceramide metabolic process GO:0006677 5 5 0,000 0,03299564 0,10859102 ! neuron recognition GO:0008038 5 5 0,000 0,03299564 0,10839745 ! negative regulation of focal adhesion formation GO:0051895 6 5 0,000 0,03299564 0,10820458 ! hair follicle maturation GO:0048820 5 5 0,000 0,03299564 0,10801238 ! phosphatidylinositol biosynthetic process GO:0006661 5 5 0,000 0,03299564 0,10782087 ! regulation of mitochondrial membrane potential GO:0051881 5 5 0,000 0,03299564 0,10763004 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 0,03299564 0,10743988 GO:0009155|purine deoxyribonucleotide catabolic process, ! regulation of interleukin-12 production GO:0032655 5 5 0,000 0,03299564 0,10725039 ! positive regulation of monooxygenase activity GO:0032770 5 5 0,000 0,03299564 0,10706157 ! postreplication repair GO:0006301 5 5 0,000 0,03299564 0,10687341 ! spinal cord motor neuron differentiation GO:0021522 5 5 0,000 0,03299564 0,10668592 GO:0021517|ventral spinal cord development, ! cellular pigmentation GO:0033059 5 5 0,000 0,03299564 0,10649908 ! histone methylation GO:0016571 5 5 0,000 0,03299564 0,10631289 ! DNA methylation GO:0006306 5 5 0,000 0,03299564 0,10612735 GO:0006305|DNA alkylation, ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,03299564 0,10594246 ! T cell lineage commitment GO:0002360 5 5 0,000 0,03299564 0,10575821 ! positive regulation of immunoglobulin mediated immune response GO:0002891 5 5 0,000 0,03299564 0,1055746 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of interferon-gamma production GO:0032729 5 5 0,000 0,03299564 0,10539163 ! negative regulation of tumor necrosis factor production GO:0032720 5 5 0,000 0,03299564 0,10520929 ! intracellular cholesterol transport GO:0032367 5 5 0,000 0,03299564 0,10502759 GO:0032366|intracellular sterol transport, ! regulation of mast cell activation GO:0033003 5 5 0,000 0,03299564 0,1048465 ! morphogenesis of a polarized epithelium GO:0001738 5 5 0,000 0,03299564 0,10466605 ! regulation of hormone metabolic process GO:0032350 5 5 0,000 0,03299564 0,10448621 ! regulation of transcription from RNA polymerase III promoter GO:0006359 5 5 0,000 0,03299564 0,10430698 ! regulation of inflammatory response to antigenic stimulus GO:0002861 5 5 0,000 0,03299564 0,10412838 ! sterol catabolic process GO:0016127 5 5 0,000 0,03299564 0,10395038 GO:0006707|cholesterol catabolic process, ! negative regulation of oxidoreductase activity GO:0051354 5 5 0,000 0,03299564 0,10377299 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 5 5 0,000 0,03299564 0,1035962 ! detection of biotic stimulus GO:0009595 5 5 0,000 0,03299564 0,10342002 ! regulation of immune response to tumor cell GO:0002837 5 5 0,000 0,03299564 0,10324443 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 5 5 0,000 0,03299564 0,10306944 ! zymogen activation GO:0031638 5 5 0,000 0,03299564 0,10289505 ! positive regulation of interleukin-1 beta secretion GO:0050718 5 5 0,000 0,03299564 0,10272124 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 5 5 0,000 0,03299564 0,10254801 GO:0002820|negative regulation of adaptive immune response, ! cellular response to nutrient GO:0031670 5 5 0,000 0,03299564 0,10237537 ! negative regulation of neuroblast proliferation GO:0007406 5 5 0,000 0,03299564 0,10220331 ! peptidyl-histidine modification GO:0018202 5 5 0,000 0,03299564 0,10203183 ! nucleosome positioning GO:0016584 5 5 0,000 0,03299564 0,10186092 ! regulation of isotype switching GO:0045191 5 5 0,000 0,03299564 0,10169059 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 5 5 0,000 0,03299564 0,10152082 ! negative regulation of neurological system process GO:0031645 5 5 0,000 0,03299564 0,10135162 ! regulation of myoblast differentiation GO:0045661 5 5 0,000 0,03299564 0,10118298 ! glutathione biosynthetic process GO:0006750 5 5 0,000 0,03299564 0,1010149 ! NADPH regeneration GO:0006740 5 5 0,000 0,03299564 0,10084738 GO:0006098|pentose-phosphate shunt, ! positive regulation of erythrocyte differentiation GO:0045648 5 5 0,000 0,03299564 0,10068042 ! positive regulation of epidermis development GO:0045684 5 5 0,000 0,03299564 0,100514 ! musculoskeletal movement GO:0050881 5 5 0,000 0,03299564 0,10034814 GO:0050879|multicellular organismal movement, ! neuromuscular process controlling posture GO:0050884 5 5 0,000 0,03299564 0,10018282 ! sarcomere organization GO:0045214 5 5 0,000 0,03299564 0,10001805 ! regulation of epidermal cell differentiation GO:0045604 5 5 0,000 0,03299564 0,09985381 ! activation of NF-kappaB-inducing kinase activity GO:0007250 5 5 0,000 0,03299564 0,09969012 ! negative regulation of glucose transport GO:0010829 5 5 0,000 0,03299564 0,09952696 GO:0046325|negative regulation of glucose import, ! oocyte differentiation GO:0009994 5 5 0,000 0,03299564 0,09936433 GO:0048599|oocyte development, ! dopamine biosynthetic process GO:0042416 5 5 0,000 0,03299564 0,09920224 ! regulation of protein homodimerization activity GO:0043496 6 5 0,000 0,03299564 0,09904067 ! spleen development GO:0048536 5 5 0,000 0,03299564 0,09887963 ! male genitalia development GO:0030539 5 5 0,000 0,03299564 0,09871911 ! nicotinamide nucleotide biosynthetic process GO:0019359 5 5 0,000 0,03299564 0,09855911 ! quaternary ammonium group transport GO:0015697 5 5 0,000 0,03299564 0,09839963 ! thyroid hormone metabolic process GO:0042403 5 5 0,000 0,03299564 0,09824067 ! leukocyte mediated cytotoxicity GO:0001909 5 5 0,000 0,03299564 0,09808221 ! positive regulation of viral reproduction GO:0048524 5 5 0,000 0,03299564 0,09792427 ! removal of superoxide radicals GO:0019430 6 5 0,000 0,03299564 0,09776684 ! regulation of fatty acid oxidation GO:0046320 5 5 0,000 0,03299564 0,09760991 ! regulation of Rac protein signal transduction GO:0035020 5 5 0,000 0,03299564 0,09745348 ! ATP catabolic process GO:0006200 5 5 0,000 0,03299564 0,09729756 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,03299564 0,09714213 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 5 5 0,000 0,03299564 0,0969872 ! regulation of fibrinolysis GO:0051917 5 5 0,000 0,03299564 0,09683276 ! embryonic gut development GO:0048566 5 5 0,000 0,03299564 0,09667881 ! negative regulation of organic acid transport GO:0032891 5 5 0,000 0,03299564 0,09652535 ! pyrimidine base metabolic process GO:0006206 5 5 0,000 0,03299564 0,09637238 ! activation of innate immune response GO:0002218 5 5 0,000 0,03299564 0,09621989 GO:0002758|innate immune response-activating signal transduction, ! catecholamine transport GO:0051937 5 5 0,000 0,03299564 0,09606789 ! negative regulation of blood vessel endothelial cell migration GO:0043537 5 5 0,000 0,03299564 0,09591636 ! regulation of NF-kappaB import into nucleus GO:0042345 5 5 0,000 0,03299564 0,09576531 ! muscle adaptation GO:0043500 5 5 0,000 0,03299564 0,09561474 ! positive regulation of actin filament bundle formation GO:0032233 5 5 0,000 0,03299564 0,09546463 ! embryonic heart tube development GO:0035050 5 5 0,000 0,03299564 0,095315 ! cardiac cell differentiation GO:0035051 6 5 0,000 0,03299564 0,09516584 ! positive regulation of homeostatic process GO:0032846 5 5 0,000 0,03299564 0,09501714 ! defense response to fungus GO:0050832 5 5 0,000 0,03299564 0,09486891 ! lysogeny GO:0030069 5 5 0,000 0,03299564 0,09472114 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 5 5 0,000 0,03299564 0,09457383 ! B cell receptor signaling pathway GO:0050853 5 5 0,000 0,03299564 0,09442698 ! positive regulation of smooth muscle contraction GO:0045987 5 5 0,000 0,03299564 0,09428058 ! response to nicotine GO:0035094 5 5 0,000 0,03299564 0,09413463 ! establishment of cell polarity GO:0030010 5 5 0,000 0,03299564 0,09398914 ! mitochondrion localization GO:0051646 5 5 0,000 0,03299564 0,09384409 ! regulation of synapse structure and activity GO:0050803 5 5 0,000 0,03299564 0,09369949 ! reproductive structure development GO:0048608 43 43 1,000 0,03319764 0,09412807 ! alcohol catabolic process GO:0046164 43 43 1,000 0,03319764 0,09398348 ! humoral immune response GO:0006959 44 44 1,000 0,03463283 0,09789618 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 45 44 1,000 0,03463283 0,09774626 ! protein import into nucleus GO:0006606 44 44 1,000 0,03463283 0,09759681 ! negative regulation of organelle organization GO:0010639 45 44 1,000 0,03463283 0,0974478 ! positive regulation of lymphocyte activation GO:0051251 44 44 1,000 0,03463283 0,09729925 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 46 45 1,000 0,03609195 0,10124425 ! steroid biosynthetic process GO:0006694 46 45 1,000 0,03609195 0,10109038 ! nuclear import GO:0051170 45 45 1,000 0,03609195 0,10093698 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 47 46 1,000 0,03757463 0,10492431 ! positive regulation of ligase activity GO:0051351 47 46 1,000 0,03757463 0,10476557 ! cellular response to hormone stimulus GO:0032870 48 46 1,000 0,03757463 0,10460731 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 47 47 1,000 0,0390805 0,10863552 ! sex differentiation GO:0007548 47 47 1,000 0,0390805 0,10847192 ! amine transport GO:0015837 47 47 1,000 0,0390805 0,1083088 ! regulation of catabolic process GO:0009894 48 47 1,000 0,0390805 0,10814618 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 6 6 0,000 0,03946578 0,10904863 ! axon extension GO:0048675 7 6 0,000 0,03946578 0,10888538 ! oligosaccharide biosynthetic process GO:0009312 6 6 0,000 0,03946578 0,10872263 ! tRNA modification GO:0006400 6 6 0,000 0,03946578 0,10856035 ! somatic diversification of immune receptors via somatic mutation GO:0002566 6 6 0,000 0,03946578 0,10839856 GO:0016446|somatic hypermutation of immunoglobulin genes, ! 'de novo' posttranslational protein folding GO:0051084 6 6 0,000 0,03946578 0,10823726 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 6 6 0,000 0,03946578 0,10807643 ! negative regulation of cellular catabolic process GO:0031330 6 6 0,000 0,03946578 0,10791608 ! virus-host interaction GO:0019048 6 6 0,000 0,03946578 0,1077562 ! regulation of S phase GO:0033261 6 6 0,000 0,03946578 0,1075968 ! myotube differentiation GO:0014902 6 6 0,000 0,03946578 0,10743787 ! regulation of B cell proliferation GO:0030888 6 6 0,000 0,03946578 0,10727941 ! bone remodeling GO:0046849 6 6 0,000 0,03946578 0,10712141 ! N-glycan processing GO:0006491 6 6 0,000 0,03946578 0,10696388 ! glycosaminoglycan catabolic process GO:0006027 6 6 0,000 0,03946578 0,10680681 ! negative regulation of JAK-STAT cascade GO:0046426 6 6 0,000 0,03946578 0,1066502 ! retina development in camera-type eye GO:0060041 6 6 0,000 0,03946578 0,10649405 ! RNA methylation GO:0001510 6 6 0,000 0,03946578 0,10633836 ! regulation of activated T cell proliferation GO:0046006 6 6 0,000 0,03946578 0,10618312 ! succinate metabolic process GO:0006105 7 6 0,000 0,03946578 0,10602833 ! artery development GO:0060840 6 6 0,000 0,03946578 0,105874 GO:0048844|artery morphogenesis, ! positive regulation of neurotransmitter transport GO:0051590 6 6 0,000 0,03946578 0,10572011 ! bile acid metabolic process GO:0008206 6 6 0,000 0,03946578 0,10556667 ! androgen metabolic process GO:0008209 6 6 0,000 0,03946578 0,10541368 ! estrogen metabolic process GO:0008210 6 6 0,000 0,03946578 0,10526112 ! limbic system development GO:0021761 7 6 0,000 0,03946578 0,10510901 ! cytoplasmic sequestering of transcription factor GO:0042994 6 6 0,000 0,03946578 0,10495734 ! positive regulation of transcription factor import into nucleus GO:0042993 6 6 0,000 0,03946578 0,10480611 ! positive regulation of heart contraction GO:0045823 6 6 0,000 0,03946578 0,1046553 ! positive regulation of gene expression, epigenetic GO:0045815 6 6 0,000 0,03946578 0,10450494 ! pathogenesis GO:0009405 6 6 0,000 0,03946578 0,104355 ! negative regulation of protein amino acid phosphorylation GO:0001933 6 6 0,000 0,03946578 0,1042055 ! positive regulation of cell growth GO:0030307 6 6 0,000 0,03946578 0,10405642 ! ribonucleoside triphosphate catabolic process GO:0009203 6 6 0,000 0,03946578 0,10390777 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! nerve growth factor receptor signaling pathway GO:0048011 6 6 0,000 0,03946578 0,10375954 ! inositol phosphate-mediated signaling GO:0048016 6 6 0,000 0,03946578 0,10361173 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 6 6 0,000 0,03946578 0,10346435 ! arginine metabolic process GO:0006525 6 6 0,000 0,03946578 0,10331738 GO:0006527|arginine catabolic process, ! regulation of catecholamine secretion GO:0050433 6 6 0,000 0,03946578 0,10317083 ! oligodendrocyte differentiation GO:0048709 6 6 0,000 0,03946578 0,1030247 ! glutamate catabolic process GO:0006538 7 6 0,000 0,03946578 0,10287898 ! telomere maintenance via telomerase GO:0007004 6 6 0,000 0,03946578 0,10273367 GO:0010833|telomere maintenance via telomere lengthening, ! L-phenylalanine metabolic process GO:0006558 6 6 0,000 0,03946578 0,10258877 GO:0006559|L-phenylalanine catabolic process, ! glucan biosynthetic process GO:0009250 6 6 0,000 0,03946578 0,10244428 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 6 6 0,000 0,03946578 0,10230019 ! V(D)J recombination GO:0033151 6 6 0,000 0,03946578 0,10215651 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 0,03946578 0,10201324 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 6 6 0,000 0,03946578 0,10187036 ! negative regulation of endothelial cell migration GO:0010596 6 6 0,000 0,03946578 0,10172788 ! regulation of heart rate GO:0002027 6 6 0,000 0,03946578 0,10158581 ! lipid digestion GO:0044241 6 6 0,000 0,03946578 0,10144412 ! asymmetric protein localization GO:0008105 6 6 0,000 0,03946578 0,10130284 ! retrograde transport, endosome to Golgi GO:0042147 6 6 0,000 0,03946578 0,10116194 ! phagocytosis, engulfment GO:0006911 6 6 0,000 0,03946578 0,10102144 ! Rac protein signal transduction GO:0016601 6 6 0,000 0,03946578 0,10088133 ! regulation of calcium ion transport into cytosol GO:0010522 6 6 0,000 0,03946578 0,1007416 ! ruffle organization GO:0031529 6 6 0,000 0,03946578 0,10060226 ! preassembly of GPI anchor in ER membrane GO:0016254 6 6 0,000 0,03946578 0,10046331 ! retinoic acid metabolic process GO:0042573 6 6 0,000 0,03946578 0,10032474 ! neutral amino acid transport GO:0015804 6 6 0,000 0,03946578 0,10018655 ! L-amino acid transport GO:0015807 6 6 0,000 0,03946578 0,10004874 ! bone mineralization GO:0030282 6 6 0,000 0,03946578 0,09991131 GO:0031214|biomineral formation, ! rRNA modification GO:0000154 6 6 0,000 0,03946578 0,09977426 ! negative regulation of ossification GO:0030279 6 6 0,000 0,03946578 0,09963758 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 6 6 0,000 0,03946578 0,09950128 GO:0002717|positive regulation of natural killer cell mediated immunity, GO:0002715|regulation of natural killer cell mediated immunity, GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 7 6 0,000 0,03946578 0,09936535 ! purine base biosynthetic process GO:0009113 6 6 0,000 0,03946578 0,09922979 ! G1 DNA damage checkpoint GO:0031571 6 6 0,000 0,03946578 0,0990946 ! negative regulation of axonogenesis GO:0050771 7 6 0,000 0,03946578 0,09895978 ! regulation of phagocytosis GO:0050764 6 6 0,000 0,03946578 0,09882532 ! regulation of organ growth GO:0046620 6 6 0,000 0,03946578 0,09869123 ! regulation of circadian rhythm GO:0042752 6 6 0,000 0,03946578 0,0985575 ! positive regulation of T cell mediated immunity GO:0002711 6 6 0,000 0,03946578 0,09842414 ! response to dsRNA GO:0043331 6 6 0,000 0,03946578 0,09829113 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 6 6 0,000 0,03946578 0,09815848 GO:0009147|pyrimidine nucleoside triphosphate metabolic process, ! genitalia development GO:0048806 6 6 0,000 0,03946578 0,0980262 ! sphingomyelin metabolic process GO:0006684 6 6 0,000 0,03946578 0,09789426 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 6 6 0,000 0,03946578 0,09776268 ! positive regulation of B cell differentiation GO:0045579 6 6 0,000 0,03946578 0,09763146 ! multicellular organismal aging GO:0010259 6 6 0,000 0,03946578 0,09750059 ! regulation of focal adhesion formation GO:0051893 7 6 0,000 0,03946578 0,09737006 ! respiratory chain complex IV assembly GO:0008535 6 6 0,000 0,03946578 0,09723989 ! erythrocyte development GO:0048821 6 6 0,000 0,03946578 0,09711006 ! renal water homeostasis GO:0003091 6 6 0,000 0,03946578 0,09698058 ! ribosomal large subunit biogenesis GO:0042273 6 6 0,000 0,03946578 0,09685145 ! regulation of Rho GTPase activity GO:0032319 6 6 0,000 0,03946578 0,09672266 ! ribosome assembly GO:0042255 6 6 0,000 0,03946578 0,09659421 ! positive regulation of Ras GTPase activity GO:0032320 6 6 0,000 0,03946578 0,0964661 ! diencephalon development GO:0021536 6 6 0,000 0,03946578 0,09633833 ! fucose catabolic process GO:0019317 6 6 0,000 0,03946578 0,0962109 GO:0042355|L-fucose catabolic process, ! nitric oxide metabolic process GO:0046209 6 6 0,000 0,03946578 0,0960838 GO:0006809|nitric oxide biosynthetic process, ! regulation of lipid transport GO:0032368 6 6 0,000 0,03946578 0,09595704 ! regulation of cell division GO:0051302 6 6 0,000 0,03946578 0,09583062 ! positive regulation of interleukin-1 secretion GO:0050716 6 6 0,000 0,03946578 0,09570452 ! cellular metabolic compound salvage GO:0043094 6 6 0,000 0,03946578 0,09557876 ! neuroblast proliferation GO:0007405 6 6 0,000 0,03946578 0,09545333 ! regulation of interleukin-1 beta secretion GO:0050706 6 6 0,000 0,03946578 0,09532823 ! nitric oxide mediated signal transduction GO:0007263 6 6 0,000 0,03946578 0,09520345 ! regulation of glucose transport GO:0010827 6 6 0,000 0,03946578 0,095079 GO:0046324|regulation of glucose import, ! intestinal absorption GO:0050892 6 6 0,000 0,03946578 0,09495488 ! methionine biosynthetic process GO:0009086 6 6 0,000 0,03946578 0,09483108 ! glutamine family amino acid biosynthetic process GO:0009084 6 6 0,000 0,03946578 0,0947076 ! serine family amino acid biosynthetic process GO:0009070 6 6 0,000 0,03946578 0,09458444 ! thymus development GO:0048538 6 6 0,000 0,03946578 0,09446161 ! lymph node development GO:0048535 6 6 0,000 0,03946578 0,09433909 ! organic cation transport GO:0015695 6 6 0,000 0,03946578 0,09421689 ! negative regulation of BMP signaling pathway GO:0030514 6 6 0,000 0,03946578 0,094095 ! regulation of RNA splicing GO:0043484 6 6 0,000 0,03946578 0,09397343 ! regulation of cellular carbohydrate catabolic process GO:0043471 6 6 0,000 0,03946578 0,09385218 GO:0043470|regulation of carbohydrate catabolic process, GO:0006110|regulation of glycolysis, ! positive regulation of JNK cascade GO:0046330 7 6 0,000 0,03946578 0,09373123 ! sperm-egg recognition GO:0035036 7 6 0,000 0,03946578 0,0936106 GO:0007339|binding of sperm to zona pellucida, ! germ cell migration GO:0008354 6 6 0,000 0,03946578 0,09349028 ! establishment or maintenance of apical/basal cell polarity GO:0035088 6 6 0,000 0,03946578 0,09337027 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 6 6 0,000 0,03946578 0,09325056 ! alditol metabolic process GO:0019400 6 6 0,000 0,03946578 0,09313116 ! regulation of synaptic transmission, GABAergic GO:0032228 6 6 0,000 0,03946578 0,09301207 ! regulation of amino acid transport GO:0051955 6 6 0,000 0,03946578 0,09289328 ! regulation of embryonic development GO:0045995 6 6 0,000 0,03946578 0,09277479 ! negative regulation of immune effector process GO:0002698 6 6 0,000 0,03946578 0,09265661 ! actin filament organization GO:0007015 50 48 1,000 0,04060919 0,09521977 ! regulation of ubiquitin-protein ligase activity GO:0051438 49 48 1,000 0,04060919 0,09509878 ! regulation of cell cycle process GO:0010564 50 48 1,000 0,04060919 0,09497809 ! protein localization in nucleus GO:0034504 48 48 1,000 0,04060919 0,09485771 ! DNA recombination GO:0006310 48 48 1,000 0,04060919 0,09473764 ! leukocyte differentiation GO:0002521 50 49 1,000 0,04216036 0,09823203 ! response to nutrient GO:0007584 49 49 1,000 0,04216036 0,098108 ! response to bacterium GO:0009617 50 49 1,000 0,04216036 0,09798428 ! regulation of ligase activity GO:0051340 50 49 1,000 0,04216036 0,09786088 ! positive regulation of cell activation GO:0050867 49 49 1,000 0,04216036 0,09773778 GO:0002696|positive regulation of leukocyte activation, ! regulation of defense response GO:0031347 50 50 1,000 0,04373364 0,10125765 ! anatomical structure homeostasis GO:0060249 51 50 1,000 0,04373364 0,10113061 ! respiratory burst GO:0045730 7 7 0,000 0,04589356 0,10599228 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 7 7 0,000 0,04589356 0,10585962 ! negative regulation of cell projection organization GO:0031345 8 7 0,000 0,04589356 0,1057273 ! positive regulation of blood pressure GO:0045777 7 7 0,000 0,04589356 0,10559531 ! positive regulation of cellular catabolic process GO:0031331 7 7 0,000 0,04589356 0,10546364 ! pteridine and derivative biosynthetic process GO:0042559 7 7 0,000 0,04589356 0,1053323 ! positive regulation of GTPase activity GO:0043547 7 7 0,000 0,04589356 0,10520129 ! SMAD protein nuclear translocation GO:0007184 7 7 0,000 0,04589356 0,10507061 ! cellular protein complex disassembly GO:0043624 8 7 0,000 0,04589356 0,10494025 GO:0043241|protein complex disassembly, ! hair follicle morphogenesis GO:0031069 7 7 0,000 0,04589356 0,10481021 ! gene silencing by RNA GO:0031047 7 7 0,000 0,04589356 0,10468049 ! regulation of receptor-mediated endocytosis GO:0048259 7 7 0,000 0,04589356 0,1045511 ! oxaloacetate metabolic process GO:0006107 7 7 0,000 0,04589356 0,10442202 ! regulation of neurotransmitter transport GO:0051588 7 7 0,000 0,04589356 0,10429327 ! keratinocyte proliferation GO:0043616 7 7 0,000 0,04589356 0,10416483 ! axis specification GO:0009798 7 7 0,000 0,04589356 0,1040367 ! negative regulation of muscle cell differentiation GO:0051148 7 7 0,000 0,04589356 0,10390889 ! visual behavior GO:0007632 7 7 0,000 0,04589356 0,1037814 GO:0008542|visual learning, ! startle response GO:0001964 7 7 0,000 0,04589356 0,10365421 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 8 7 0,000 0,04589356 0,10352734 ! positive regulation of lipid metabolic process GO:0045834 7 7 0,000 0,04589356 0,10340078 ! negative regulation of lipid metabolic process GO:0045833 7 7 0,000 0,04589356 0,10327453 ! regulation of interferon-gamma biosynthetic process GO:0045072 7 7 0,000 0,04589356 0,10314858 ! endothelial cell differentiation GO:0045446 7 7 0,000 0,04589356 0,10302295 ! negative regulation of striated muscle development GO:0045843 7 7 0,000 0,04589356 0,10289761 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 7 7 0,000 0,04589356 0,10277259 ! digestive system development GO:0055123 7 7 0,000 0,04589356 0,10264786 GO:0048546|digestive tract morphogenesis, GO:0048547|gut morphogenesis, ! hemoglobin metabolic process GO:0020027 7 7 0,000 0,04589356 0,10252344 ! regulation of exit from mitosis GO:0007096 7 7 0,000 0,04589356 0,10239932 ! protein targeting to ER GO:0045047 8 7 0,000 0,04589356 0,1022755 ! cell differentiation in spinal cord GO:0021515 7 7 0,000 0,04589356 0,10215198 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 7 7 0,000 0,04589356 0,10202876 ! endoderm development GO:0007492 7 7 0,000 0,04589356 0,10190583 ! regulation of defense response to virus GO:0050688 7 7 0,000 0,04589356 0,1017832 ! glycolipid biosynthetic process GO:0009247 7 7 0,000 0,04589356 0,10166086 GO:0006688|glycosphingolipid biosynthetic process, ! response to hexose stimulus GO:0009746 7 7 0,000 0,04589356 0,10153882 GO:0034284|response to monosaccharide stimulus, GO:0009749|response to glucose stimulus, ! positive regulation of survival gene product expression GO:0045885 7 7 0,000 0,04589356 0,10141707 ! regulation of skeletal muscle fiber development GO:0048742 7 7 0,000 0,04589356 0,10129562 ! cardiac muscle tissue development GO:0048738 7 7 0,000 0,04589356 0,10117445 ! nucleotide-sugar metabolic process GO:0009225 7 7 0,000 0,04589356 0,10105357 ! complement activation, alternative pathway GO:0006957 7 7 0,000 0,04589356 0,10093298 ! arachidonic acid secretion GO:0050482 7 7 0,000 0,04589356 0,10081268 GO:0032309|icosanoid secretion, ! polyamine biosynthetic process GO:0006596 7 7 0,000 0,04589356 0,10069267 ! response to X-ray GO:0010165 7 7 0,000 0,04589356 0,10057294 ! regulation of intracellular pH GO:0051453 7 7 0,000 0,04589356 0,10045349 ! UV protection GO:0009650 7 7 0,000 0,04589356 0,10033433 ! DNA integration GO:0015074 7 7 0,000 0,04589356 0,10021545 ! myofibril assembly GO:0030239 7 7 0,000 0,04589356 0,10009685 GO:0055002|striated muscle cell development, ! positive regulation of carbohydrate metabolic process GO:0045913 7 7 0,000 0,04589356 0,09997853 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! positive regulation of muscle contraction GO:0045933 7 7 0,000 0,04589356 0,0998605 ! negative regulation of muscle contraction GO:0045932 7 7 0,000 0,04589356 0,09974274 ! chondroitin sulfate biosynthetic process GO:0030206 7 7 0,000 0,04589356 0,09962525 GO:0030204|chondroitin sulfate metabolic process, ! regulation of exocytosis GO:0017157 8 7 0,000 0,04589356 0,09950805 ! phosphatidylcholine biosynthetic process GO:0006656 7 7 0,000 0,04589356 0,09939112 ! heparan sulfate proteoglycan metabolic process GO:0030201 7 7 0,000 0,04589356 0,09927446 GO:0015012|heparan sulfate proteoglycan biosynthetic process, ! stem cell development GO:0048864 7 7 0,000 0,04589356 0,09915808 GO:0019827|stem cell maintenance, ! alpha-beta T cell differentiation GO:0046632 7 7 0,000 0,04589356 0,09904197 ! negative regulation of myeloid leukocyte differentiation GO:0002762 7 7 0,000 0,04589356 0,09892613 ! axon cargo transport GO:0008088 7 7 0,000 0,04589356 0,09881056 ! eating behavior GO:0042755 7 7 0,000 0,04589356 0,09869526 ! RNA-dependent DNA replication GO:0006278 7 7 0,000 0,04589356 0,09858023 ! purine nucleoside triphosphate catabolic process GO:0009146 7 7 0,000 0,04589356 0,09846547 ! regulation of interleukin-8 production GO:0032677 7 7 0,000 0,04589356 0,09835098 ! purine ribonucleotide catabolic process GO:0009154 7 7 0,000 0,04589356 0,09823675 ! ribosomal small subunit biogenesis GO:0042274 7 7 0,000 0,04589356 0,09812278 ! protein import into peroxisome matrix GO:0016558 7 7 0,000 0,04589356 0,09800908 ! induction of an organ GO:0001759 7 7 0,000 0,04589356 0,09789565 ! leukocyte activation during immune response GO:0002366 7 7 0,000 0,04589356 0,09778247 GO:0002263|cell activation during immune response, ! response to estradiol stimulus GO:0032355 7 7 0,000 0,04589356 0,09766956 ! intracellular lipid transport GO:0032365 7 7 0,000 0,04589356 0,09755691 ! detection of chemical stimulus GO:0009593 8 7 0,000 0,04589356 0,09744452 ! negative regulation of cytokine secretion GO:0050710 7 7 0,000 0,04589356 0,09733238 ! regulation of interleukin-1 secretion GO:0050704 7 7 0,000 0,04589356 0,0972205 ! natural killer cell activation GO:0030101 7 7 0,000 0,04589356 0,09710889 ! response to gamma radiation GO:0010332 8 7 0,000 0,04589356 0,09699752 ! NADP metabolic process GO:0006739 7 7 0,000 0,04589356 0,09688641 ! neuromuscular synaptic transmission GO:0007274 7 7 0,000 0,04589356 0,09677556 ! synaptic transmission, cholinergic GO:0007271 7 7 0,000 0,04589356 0,09666496 ! ubiquinone metabolic process GO:0006743 7 7 0,000 0,04589356 0,09655461 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, GO:0042375|quinone cofactor metabolic process, ! regulation of osteoclast differentiation GO:0045670 7 7 0,000 0,04589356 0,09644451 ! negative regulation of cell-substrate adhesion GO:0010812 8 7 0,000 0,04589356 0,09633467 GO:0001953|negative regulation of cell-matrix adhesion, ! multicellular organismal water homeostasis GO:0050891 7 7 0,000 0,04589356 0,09622507 ! cell-cell recognition GO:0009988 8 7 0,000 0,04589356 0,09611573 ! hormone catabolic process GO:0042447 7 7 0,000 0,04589356 0,09600663 ! dopamine metabolic process GO:0042417 7 7 0,000 0,04589356 0,09589778 ! cAMP biosynthetic process GO:0006171 7 7 0,000 0,04589356 0,09578917 ! oxygen transport GO:0015671 7 7 0,000 0,04589356 0,09568081 ! pyridine nucleotide biosynthetic process GO:0019363 7 7 0,000 0,04589356 0,0955727 ! biogenic amine catabolic process GO:0042402 7 7 0,000 0,04589356 0,09546483 ! regulation of axon extension GO:0030516 7 7 0,000 0,04589356 0,0953572 ! cell killing GO:0001906 7 7 0,000 0,04589356 0,09524982 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 7 7 0,000 0,04589356 0,09514268 ! adult feeding behavior GO:0008343 7 7 0,000 0,04589356 0,09503577 ! pyrimidine nucleotide catabolic process GO:0006244 7 7 0,000 0,04589356 0,09492911 ! positive regulation of protein polymerization GO:0032273 7 7 0,000 0,04589356 0,09482269 ! T cell receptor signaling pathway GO:0050852 7 7 0,000 0,04589356 0,09471651 ! response to cold GO:0009409 7 7 0,000 0,04589356 0,09461056 ! cholesterol metabolic process GO:0008203 52 52 1,000 0,04694515 0,09667029 ! response to light stimulus GO:0009416 53 52 1,000 0,04694515 0,0965624 ! carbohydrate catabolic process GO:0016052 53 53 1,000 0,04858269 0,09981929 ! protein amino acid dephosphorylation GO:0006470 55 54 1,000 0,05024097 0,10311147 ! response to virus GO:0009615 54 54 1,000 0,05024097 0,10299677 ! microtubule cytoskeleton organization GO:0000226 55 55 1,000 0,05191964 0,10631988 ! in utero embryonic development GO:0001701 55 55 1,000 0,05191964 0,10620188 ! regulation of cell adhesion GO:0030155 56 55 1,000 0,05191964 0,10608414 ! regulation of skeletal muscle tissue development GO:0048641 8 8 0,000 0,05227926 0,10670064 ! negative regulation of muscle development GO:0048635 8 8 0,000 0,05227926 0,10658261 ! very-long-chain fatty acid metabolic process GO:0000038 8 8 0,000 0,05227926 0,10646484 ! positive regulation of cell killing GO:0031343 8 8 0,000 0,05227926 0,10634733 ! superoxide anion generation GO:0042554 8 8 0,000 0,05227926 0,10623008 ! sulfur amino acid biosynthetic process GO:0000097 8 8 0,000 0,05227926 0,10611308 ! cGMP metabolic process GO:0046068 8 8 0,000 0,05227926 0,10599635 GO:0006182|cGMP biosynthetic process, ! thyroid gland development GO:0030878 8 8 0,000 0,05227926 0,10587987 ! 'de novo' protein folding GO:0006458 8 8 0,000 0,05227926 0,10576364 ! dicarboxylic acid transport GO:0006835 8 8 0,000 0,05227926 0,10564767 ! phosphoinositide phosphorylation GO:0046854 8 8 0,000 0,05227926 0,10553196 ! embryonic hindlimb morphogenesis GO:0035116 8 8 0,000 0,05227926 0,1054165 ! zinc ion transport GO:0006829 8 8 0,000 0,05227926 0,10530129 ! embryonic forelimb morphogenesis GO:0035115 8 8 0,000 0,05227926 0,10518633 ! folic acid and derivative biosynthetic process GO:0009396 8 8 0,000 0,05227926 0,10507162 ! regulation of neuronal synaptic plasticity GO:0048168 8 8 0,000 0,05227926 0,10495717 ! cardiac muscle contraction GO:0060048 8 8 0,000 0,05227926 0,10484296 ! lipid localization GO:0010876 8 8 0,000 0,05227926 0,104729 GO:0019915|lipid storage, ! response to pain GO:0048265 8 8 0,000 0,05227926 0,10461529 ! response to cAMP GO:0051591 8 8 0,000 0,05227926 0,10450182 ! COPI coating of Golgi vesicle GO:0048205 8 8 0,000 0,05227926 0,1043886 GO:0048200|Golgi transport vesicle coating, ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 8 0,000 0,05227926 0,10427563 ! negative regulation of transcription factor import into nucleus GO:0042992 8 8 0,000 0,05227926 0,1041629 ! negative regulation of ion transport GO:0043271 8 8 0,000 0,05227926 0,10405041 ! regulation of response to extracellular stimulus GO:0032104 8 8 0,000 0,05227926 0,10393817 GO:0032107|regulation of response to nutrient levels, ! adult walking behavior GO:0007628 8 8 0,000 0,05227926 0,10382616 ! sensory perception of taste GO:0050909 8 8 0,000 0,05227926 0,1037144 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 8 8 0,000 0,05227926 0,10360288 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! T cell selection GO:0045058 8 8 0,000 0,05227926 0,1034916 ! negative regulation of proteolysis GO:0045861 8 8 0,000 0,05227926 0,10338056 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 8 8 0,000 0,05227926 0,10326975 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 8 8 0,000 0,05227926 0,10315919 ! sperm motility GO:0030317 8 8 0,000 0,05227926 0,10304885 ! regulation of striated muscle contraction GO:0006942 8 8 0,000 0,05227926 0,10293876 ! glycine metabolic process GO:0006544 8 8 0,000 0,05227926 0,1028289 ! ribonucleotide catabolic process GO:0009261 8 8 0,000 0,05227926 0,10271927 ! negative regulation of microtubule depolymerization GO:0007026 8 8 0,000 0,05227926 0,10260988 GO:0031114|regulation of microtubule depolymerization, ! phosphagen metabolic process GO:0006599 8 8 0,000 0,05227926 0,10250072 GO:0006600|creatine metabolic process, ! polyamine metabolic process GO:0006595 8 8 0,000 0,05227926 0,10239179 ! Golgi organization GO:0007030 8 8 0,000 0,05227926 0,1022831 ! regulation of stress fiber formation GO:0051492 9 8 0,000 0,05227926 0,10217463 ! fructose metabolic process GO:0006000 8 8 0,000 0,05227926 0,1020664 ! mannose metabolic process GO:0006013 9 8 0,000 0,05227926 0,10195839 ! NAD metabolic process GO:0019674 8 8 0,000 0,05227926 0,10185061 ! negative regulation of mitotic cell cycle GO:0045930 9 8 0,000 0,05227926 0,10174306 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 8 8 0,000 0,05227926 0,10163574 ! response to fungus GO:0009620 8 8 0,000 0,05227926 0,10152864 ! stem cell differentiation GO:0048863 8 8 0,000 0,05227926 0,10142177 ! alpha-beta T cell activation GO:0046631 8 8 0,000 0,05227926 0,10131512 ! embryonic digit morphogenesis GO:0042733 8 8 0,000 0,05227926 0,1012087 ! regulation of cytokine production during immune response GO:0002718 8 8 0,000 0,05227926 0,1011025 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 0,05227926 0,10099652 ! regulation of vasodilation GO:0042312 8 8 0,000 0,05227926 0,10089076 ! vasoconstriction GO:0042310 8 8 0,000 0,05227926 0,10078523 ! regulation of T cell mediated immunity GO:0002709 8 8 0,000 0,05227926 0,10067992 ! muscle cell development GO:0055001 8 8 0,000 0,05227926 0,10057482 ! nucleoside triphosphate catabolic process GO:0009143 8 8 0,000 0,05227926 0,10046995 ! regulation of fatty acid metabolic process GO:0019217 8 8 0,000 0,05227926 0,10036529 ! sensory perception of pain GO:0019233 8 8 0,000 0,05227926 0,10026085 ! gastrulation with mouth forming second GO:0001702 8 8 0,000 0,05227926 0,10015663 ! immunoglobulin production during immune response GO:0002381 8 8 0,000 0,05227926 0,10005263 GO:0002208|somatic diversification of immunoglobulins during immune response, GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! mRNA cleavage GO:0006379 8 8 0,000 0,05227926 0,09994884 ! chromatin silencing GO:0006342 8 8 0,000 0,05227926 0,09984526 ! tissue regeneration GO:0042246 8 8 0,000 0,05227926 0,0997419 ! negative regulation of blood coagulation GO:0030195 9 8 0,000 0,05227926 0,09963876 ! T cell homeostasis GO:0043029 8 8 0,000 0,05227926 0,09953583 ! peptide biosynthetic process GO:0043043 9 8 0,000 0,05227926 0,09943311 ! water homeostasis GO:0030104 8 8 0,000 0,05227926 0,0993306 ! cofactor transport GO:0051181 8 8 0,000 0,05227926 0,0992283 ! acid secretion GO:0046717 8 8 0,000 0,05227926 0,09912621 ! C21-steroid hormone biosynthetic process GO:0006700 8 8 0,000 0,05227926 0,09902434 ! protein-chromophore linkage GO:0018298 9 8 0,000 0,05227926 0,09892267 ! branched chain family amino acid metabolic process GO:0009081 8 8 0,000 0,05227926 0,09882121 ! catecholamine biosynthetic process GO:0042423 8 8 0,000 0,05227926 0,09871996 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 8 8 0,000 0,05227926 0,09861891 ! regulation of generation of precursor metabolites and energy GO:0043467 8 8 0,000 0,05227926 0,09851808 ! aromatic compound biosynthetic process GO:0019438 8 8 0,000 0,05227926 0,09841745 ! release of cytochrome c from mitochondria GO:0001836 9 8 0,000 0,05227926 0,09831702 ! regulation of organic acid transport GO:0032890 8 8 0,000 0,05227926 0,0982168 ! positive regulation of calcium ion transport GO:0051928 8 8 0,000 0,05227926 0,09811678 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 8 8 0,000 0,05227926 0,09801697 ! regulation of multi-organism process GO:0043900 8 8 0,000 0,05227926 0,09791736 ! positive regulation of amine transport GO:0051954 8 8 0,000 0,05227926 0,09781795 ! developmental induction GO:0031128 8 8 0,000 0,05227926 0,09771874 GO:0045168|cell-cell signaling involved in cell fate specification, ! positive regulation of calcium-mediated signaling GO:0050850 8 8 0,000 0,05227926 0,09761974 ! actin filament polymerization GO:0030041 9 8 0,000 0,05227926 0,09752093 ! cytoplasmic sequestering of protein GO:0051220 8 8 0,000 0,05227926 0,09742232 ! peptide hormone processing GO:0016486 8 8 0,000 0,05227926 0,09732392 ! positive regulation of synaptic transmission GO:0050806 8 8 0,000 0,05227926 0,09722571 ! regulation of steroid biosynthetic process GO:0050810 8 8 0,000 0,05227926 0,0971277 ! reproductive developmental process GO:0003006 56 56 1,000 0,05361837 0,09951527 ! extracellular structure organization GO:0043062 56 56 1,000 0,05361837 0,09941515 ! lactation GO:0007595 10 9 0,000 0,05862314 0,10858538 ! embryonic pattern specification GO:0009880 10 9 0,000 0,05862314 0,10847636 ! positive regulation of cell size GO:0045793 9 9 0,000 0,05862314 0,10836756 ! regulation of membrane protein ectodomain proteolysis GO:0051043 9 9 0,000 0,05862314 0,10825897 ! cortical actin cytoskeleton organization GO:0030866 10 9 0,000 0,05862314 0,1081506 ! viral genome replication GO:0019079 9 9 0,000 0,05862314 0,10804245 ! phospholipid catabolic process GO:0009395 9 9 0,000 0,05862314 0,10793452 ! copper ion transport GO:0006825 9 9 0,000 0,05862314 0,1078268 ! lipid phosphorylation GO:0046834 9 9 0,000 0,05862314 0,10771929 ! aminoglycan catabolic process GO:0006026 9 9 0,000 0,05862314 0,107612 ! Golgi vesicle budding GO:0048194 9 9 0,000 0,05862314 0,10750493 ! regulation of cell-cell adhesion GO:0022407 9 9 0,000 0,05862314 0,10739806 ! RNA polyadenylation GO:0043631 9 9 0,000 0,05862314 0,10729141 GO:0006378|mRNA polyadenylation, ! gamma-aminobutyric acid signaling pathway GO:0007214 9 9 0,000 0,05862314 0,10718497 ! regulation of postsynaptic membrane potential GO:0060078 9 9 0,000 0,05862314 0,10707874 ! phospholipid efflux GO:0033700 9 9 0,000 0,05862314 0,10697273 ! response to alkaloid GO:0043279 10 9 0,000 0,05862314 0,10686692 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 9 9 0,000 0,05862314 0,10676132 ! cytokine biosynthetic process GO:0042089 9 9 0,000 0,05862314 0,10665593 GO:0042107|cytokine metabolic process, ! negative regulation of gene expression, epigenetic GO:0045814 9 9 0,000 0,05862314 0,10655074 ! regulation of interleukin-2 biosynthetic process GO:0045076 9 9 0,000 0,05862314 0,10644577 ! response to ethanol GO:0045471 9 9 0,000 0,05862314 0,106341 ! pyrimidine ribonucleotide metabolic process GO:0009218 9 9 0,000 0,05862314 0,10623643 ! activation of pro-apoptotic gene products GO:0008633 9 9 0,000 0,05862314 0,10613208 ! methionine metabolic process GO:0006555 9 9 0,000 0,05862314 0,10602792 ! glutamine metabolic process GO:0006541 9 9 0,000 0,05862314 0,10592397 ! cerebral cortex development GO:0021987 9 9 0,000 0,05862314 0,10582023 ! response to osmotic stress GO:0006970 9 9 0,000 0,05862314 0,10571669 ! pigmentation during development GO:0048066 9 9 0,000 0,05862314 0,10561335 ! reverse cholesterol transport GO:0043691 9 9 0,000 0,05862314 0,10551021 ! central nervous system neuron development GO:0021954 10 9 0,000 0,05862314 0,10540727 ! pyrimidine ribonucleoside metabolic process GO:0046131 9 9 0,000 0,05862314 0,10530453 ! nucleobase biosynthetic process GO:0046112 9 9 0,000 0,05862314 0,105202 ! substrate-bound cell migration GO:0006929 9 9 0,000 0,05862314 0,10509966 ! neurotransmitter metabolic process GO:0042133 11 9 0,000 0,05862314 0,10499752 ! negative regulation of caspase activity GO:0043154 9 9 0,000 0,05862314 0,10489559 ! branching involved in ureteric bud morphogenesis GO:0001658 9 9 0,000 0,05862314 0,10479384 GO:0060675|ureteric bud morphogenesis, ! L-glutamate transport GO:0015813 9 9 0,000 0,05862314 0,1046923 GO:0015800|acidic amino acid transport, ! regulation of dephosphorylation GO:0035303 9 9 0,000 0,05862314 0,10459095 ! cotranslational protein targeting to membrane GO:0006613 10 9 0,000 0,05862314 0,1044898 ! ventricular cardiac muscle morphogenesis GO:0055010 9 9 0,000 0,05862314 0,10438884 ! behavioral interaction between organisms GO:0051705 9 9 0,000 0,05862314 0,10428808 ! negative regulation of protein import into nucleus GO:0042308 9 9 0,000 0,05862314 0,10418751 ! positive regulation of protein import into nucleus GO:0042307 9 9 0,000 0,05862314 0,10408714 ! DNA replication initiation GO:0006270 9 9 0,000 0,05862314 0,10398696 ! prostaglandin metabolic process GO:0006693 9 9 0,000 0,05862314 0,10388697 GO:0006692|prostanoid metabolic process, ! T cell differentiation in the thymus GO:0033077 9 9 0,000 0,05862314 0,10378718 ! regulation of cellular pH GO:0030641 9 9 0,000 0,05862314 0,10368757 ! DNA fragmentation involved in apoptosis GO:0006309 9 9 0,000 0,05862314 0,10358816 ! regulation of immunoglobulin mediated immune response GO:0002889 9 9 0,000 0,05862314 0,10348894 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 10 9 0,000 0,05862314 0,10338991 ! positive regulation of oxidoreductase activity GO:0051353 9 9 0,000 0,05862314 0,10329106 ! positive regulation of cytokine secretion GO:0050715 9 9 0,000 0,05862314 0,10319241 ! negative regulation of inflammatory response GO:0050728 9 9 0,000 0,05862314 0,10309394 ! negative regulation of protein secretion GO:0050709 9 9 0,000 0,05862314 0,10299567 ! positive regulation of transmission of nerve impulse GO:0051971 9 9 0,000 0,05862314 0,10289757 ! collagen catabolic process GO:0030574 9 9 0,000 0,05862314 0,10279967 ! aromatic amino acid family catabolic process GO:0009074 9 9 0,000 0,05862314 0,10270195 ! purine base metabolic process GO:0006144 9 9 0,000 0,05862314 0,10260442 ! gas transport GO:0015669 9 9 0,000 0,05862314 0,10250707 ! cholesterol efflux GO:0033344 9 9 0,000 0,05862314 0,10240991 ! regulation of leukocyte mediated cytotoxicity GO:0001910 9 9 0,000 0,05862314 0,10231293 ! estrogen receptor signaling pathway GO:0030520 9 9 0,000 0,05862314 0,10221613 ! somatic recombination of immunoglobulin gene segments GO:0016447 9 9 0,000 0,05862314 0,10211952 ! regulation of actin filament bundle formation GO:0032231 10 9 0,000 0,05862314 0,10202309 ! regulation of calcium-mediated signaling GO:0050848 9 9 0,000 0,05862314 0,10192684 ! actin filament-based movement GO:0030048 9 9 0,000 0,05862314 0,10183078 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 9 9 0,000 0,05862314 0,10173489 ! dephosphorylation GO:0016311 60 59 1,000 0,05883168 0,10200074 ! carboxylic acid transport GO:0046942 59 59 1,000 0,05883168 0,10190487 GO:0015849|organic acid transport, ! sterol metabolic process GO:0016125 59 59 1,000 0,05883168 0,10180919 ! protein localization in organelle GO:0033365 59 59 1,000 0,05883168 0,10171368 ! immune effector process GO:0002252 59 59 1,000 0,05883168 0,10161836 ! protein polymerization GO:0051258 65 60 1,000 0,0606074 0,10458749 ! cellular respiration GO:0045333 62 61 1,000 0,06240157 0,10758288 ! proteasomal protein catabolic process GO:0010498 62 61 1,000 0,06240157 0,10748234 GO:0043161|proteasomal ubiquitin-dependent protein catabolic process, ! positive regulation of cellular protein metabolic process GO:0032270 61 61 1,000 0,06240157 0,10738198 ! morphogenesis of an epithelium GO:0002009 63 62 1,000 0,06421388 0,11039755 GO:0060429|epithelium development, ! protein import GO:0017038 62 62 1,000 0,06421388 0,11029466 ! protein import into nucleus, docking GO:0000059 10 10 0,000 0,06492548 0,11141309 ! regulation of protein ubiquitination GO:0031396 10 10 0,000 0,06492548 0,11130945 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 10 10 0,000 0,06492548 0,111206 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 10 10 0,000 0,06492548 0,11110274 ! regulation of glucose metabolic process GO:0010906 10 10 0,000 0,06492548 0,11099968 ! ER-associated protein catabolic process GO:0030433 10 10 0,000 0,06492548 0,11089681 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of cell killing GO:0031341 10 10 0,000 0,06492548 0,11079412 ! neuron maturation GO:0042551 10 10 0,000 0,06492548 0,11069163 ! pteridine and derivative metabolic process GO:0042558 10 10 0,000 0,06492548 0,11058933 ! cortical cytoskeleton organization GO:0030865 11 10 0,000 0,06492548 0,11048722 ! regulation of lipid biosynthetic process GO:0046890 10 10 0,000 0,06492548 0,11038529 ! glucosamine metabolic process GO:0006041 10 10 0,000 0,06492548 0,11028355 GO:0006044|N-acetylglucosamine metabolic process, ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 10 10 0,000 0,06492548 0,110182 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! inositol metabolic process GO:0006020 10 10 0,000 0,06492548 0,11008064 ! cAMP metabolic process GO:0046058 10 10 0,000 0,06492548 0,10997946 ! vesicle targeting, to, from or within Golgi GO:0048199 10 10 0,000 0,06492548 0,10987847 ! transcription from RNA polymerase III promoter GO:0006383 10 10 0,000 0,06492548 0,10977766 ! forelimb morphogenesis GO:0035136 10 10 0,000 0,06492548 0,10967704 ! glial cell development GO:0021782 10 10 0,000 0,06492548 0,10957661 ! phototransduction GO:0007602 11 10 0,000 0,06492548 0,10947635 ! auditory receptor cell differentiation GO:0042491 10 10 0,000 0,06492548 0,10937628 ! apoptotic mitochondrial changes GO:0008637 11 10 0,000 0,06492548 0,1092764 ! fat cell differentiation GO:0045444 10 10 0,000 0,06492548 0,10917669 ! myoblast differentiation GO:0045445 10 10 0,000 0,06492548 0,10907717 ! centrosome cycle GO:0007098 10 10 0,000 0,06492548 0,10897783 ! inactivation of MAPK activity GO:0000188 10 10 0,000 0,06492548 0,10887867 ! positive regulation of proteolysis GO:0045862 10 10 0,000 0,06492548 0,10877969 ! response to carbohydrate stimulus GO:0009743 10 10 0,000 0,06492548 0,10868088 ! regulation of survival gene product expression GO:0045884 10 10 0,000 0,06492548 0,10858226 ! induction of apoptosis via death domain receptors GO:0008625 10 10 0,000 0,06492548 0,10848382 ! epidermis morphogenesis GO:0048730 10 10 0,000 0,06492548 0,10838556 ! protein polyubiquitination GO:0000209 10 10 0,000 0,06492548 0,10828747 ! glutamate metabolic process GO:0006536 11 10 0,000 0,06492548 0,10818956 ! plasma membrane organization GO:0007009 10 10 0,000 0,06492548 0,10809183 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 10 10 0,000 0,06492548 0,10799427 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! lysosomal transport GO:0007041 10 10 0,000 0,06492548 0,10789689 ! cellular response to unfolded protein GO:0034620 10 10 0,000 0,06492548 0,10779969 GO:0030968|endoplasmic reticulum unfolded protein response, ! central nervous system neuron differentiation GO:0021953 11 10 0,000 0,06492548 0,10770266 ! purine ribonucleoside metabolic process GO:0046128 10 10 0,000 0,06492548 0,1076058 GO:0042278|purine nucleoside metabolic process, ! vesicle coating GO:0006901 10 10 0,000 0,06492548 0,10750912 ! cell structure disassembly during apoptosis GO:0006921 10 10 0,000 0,06492548 0,10741262 ! embryo implantation GO:0007566 11 10 0,000 0,06492548 0,10731628 ! regulation of protein binding GO:0043393 11 10 0,000 0,06492548 0,10722012 ! protein targeting to peroxisome GO:0006625 10 10 0,000 0,06492548 0,10712413 ! protein targeting to mitochondrion GO:0006626 10 10 0,000 0,06492548 0,10702831 GO:0070585|protein localization in mitochondrion, ! intermediate filament cytoskeleton organization GO:0045104 10 10 0,000 0,06492548 0,10693267 ! protein export from nucleus GO:0006611 10 10 0,000 0,06492548 0,10683719 ! negative regulation of immune response GO:0050777 10 10 0,000 0,06492548 0,10674189 ! cytolysis GO:0019835 10 10 0,000 0,06492548 0,10664675 ! positive regulation of biomineral formation GO:0070169 10 10 0,000 0,06492548 0,10655178 GO:0030501|positive regulation of bone mineralization, ! mismatch repair GO:0006298 10 10 0,000 0,06492548 0,10645699 ! regulation of B cell differentiation GO:0045577 10 10 0,000 0,06492548 0,10636236 ! histone deacetylation GO:0016575 10 10 0,000 0,06492548 0,1062679 ! mRNA splice site selection GO:0006376 11 10 0,000 0,06492548 0,10617361 ! synaptic vesicle transport GO:0048489 11 10 0,000 0,06492548 0,10607948 ! positive regulation of neurological system process GO:0031646 10 10 0,000 0,06492548 0,10598552 ! sphingolipid biosynthetic process GO:0030148 10 10 0,000 0,06492548 0,10589173 GO:0046467|membrane lipid biosynthetic process, ! sphingolipid catabolic process GO:0030149 10 10 0,000 0,06492548 0,1057981 GO:0046466|membrane lipid catabolic process, ! nerve-nerve synaptic transmission GO:0007270 10 10 0,000 0,06492548 0,10570464 ! regulation of erythrocyte differentiation GO:0045646 10 10 0,000 0,06492548 0,10561134 ! regulation of epidermis development GO:0045682 10 10 0,000 0,06492548 0,10551821 ! folic acid and derivative metabolic process GO:0006760 10 10 0,000 0,06492548 0,10542525 ! negative regulation of neuron differentiation GO:0045665 10 10 0,000 0,06492548 0,10533244 ! aspartate family amino acid biosynthetic process GO:0009067 10 10 0,000 0,06492548 0,1052398 ! regulation of BMP signaling pathway GO:0030510 10 10 0,000 0,06492548 0,10514732 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 10 10 0,000 0,06492548 0,10505501 ! lymphocyte homeostasis GO:0002260 10 10 0,000 0,06492548 0,10496285 ! gut development GO:0048565 10 10 0,000 0,06492548 0,10487086 ! embryonic organ morphogenesis GO:0048562 10 10 0,000 0,06492548 0,10477903 ! positive regulation of neuron apoptosis GO:0043525 10 10 0,000 0,06492548 0,10468736 ! mRNA 3'-end processing GO:0031124 10 10 0,000 0,06492548 0,10459585 ! antigen receptor-mediated signaling pathway GO:0050851 10 10 0,000 0,06492548 0,1045045 ! negative regulation of coagulation GO:0050819 11 10 0,000 0,06492548 0,10441331 ! protein stabilization GO:0050821 10 10 0,000 0,06492548 0,10432228 ! regulation of secretion GO:0051046 65 63 1,000 0,066044 0,10602709 ! glucose metabolic process GO:0006006 63 63 1,000 0,066044 0,10593481 ! regulation of hormone levels GO:0010817 66 65 1,000 0,06975649 0,11179237 ! protein secretion GO:0009306 11 11 0,000 0,07118653 0,11398503 ! oligosaccharide metabolic process GO:0009311 11 11 0,000 0,07118653 0,11388609 ! negative regulation of defense response GO:0031348 11 11 0,000 0,07118653 0,11378731 ! G1 phase of mitotic cell cycle GO:0000080 12 11 0,000 0,07118653 0,11368871 ! determination of bilateral symmetry GO:0009855 11 11 0,000 0,07118653 0,11359028 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! positive regulation of hormone secretion GO:0046887 11 11 0,000 0,07118653 0,11349202 ! phosphatidylinositol metabolic process GO:0046488 11 11 0,000 0,07118653 0,11339393 ! skin development GO:0043588 11 11 0,000 0,07118653 0,113296 ! signal complex assembly GO:0007172 11 11 0,000 0,07118653 0,11319825 ! microtubule-based transport GO:0010970 11 11 0,000 0,07118653 0,11310067 ! endothelial cell migration GO:0043542 11 11 0,000 0,07118653 0,11300325 ! peroxisomal transport GO:0043574 11 11 0,000 0,07118653 0,112906 ! protein amino acid methylation GO:0006479 11 11 0,000 0,07118653 0,11280892 GO:0008213|protein amino acid alkylation, ! heart contraction GO:0060047 11 11 0,000 0,07118653 0,112712 GO:0003015|heart process, ! detection of light stimulus involved in sensory perception GO:0050962 12 11 0,000 0,07118653 0,11261526 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 11 11 0,000 0,07118653 0,11251867 ! T cell proliferation GO:0042098 11 11 0,000 0,07118653 0,11242226 ! regulation of transmembrane transporter activity GO:0022898 11 11 0,000 0,07118653 0,112326 GO:0032412|regulation of ion transmembrane transporter activity, GO:0032409|regulation of transporter activity, ! negative regulation of endothelial cell proliferation GO:0001937 11 11 0,000 0,07118653 0,11222992 ! regulation of viral genome replication GO:0045069 11 11 0,000 0,07118653 0,11213399 ! spinal cord development GO:0021510 11 11 0,000 0,07118653 0,11203823 ! activation of MAPKK activity GO:0000186 12 11 0,000 0,07118653 0,11194264 ! smooth muscle contraction GO:0006939 11 11 0,000 0,07118653 0,11184721 ! cellular response to starvation GO:0009267 11 11 0,000 0,07118653 0,11175194 ! cellular macromolecular complex disassembly GO:0034623 12 11 0,000 0,07118653 0,11165683 ! digestive system process GO:0022600 11 11 0,000 0,07118653 0,11156188 ! mitotic spindle organization GO:0007052 11 11 0,000 0,07118653 0,1114671 ! fucose metabolic process GO:0006004 11 11 0,000 0,07118653 0,11137247 ! membrane budding GO:0006900 11 11 0,000 0,07118653 0,11127801 ! apoptotic nuclear changes GO:0030262 11 11 0,000 0,07118653 0,11118371 ! monoamine transport GO:0015844 11 11 0,000 0,07118653 0,11108956 ! regulation of cellular ketone metabolic process GO:0010565 11 11 0,000 0,07118653 0,11099558 ! response to lipopolysaccharide GO:0032496 11 11 0,000 0,07118653 0,11090175 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 11 11 0,000 0,07118653 0,11080809 ! body fluid secretion GO:0007589 11 11 0,000 0,07118653 0,11071458 ! G1/S transition checkpoint GO:0031575 12 11 0,000 0,07118653 0,11062123 ! intermediate filament-based process GO:0045103 11 11 0,000 0,07118653 0,11052803 ! cardiac muscle tissue morphogenesis GO:0055008 11 11 0,000 0,07118653 0,11043499 GO:0060415|muscle tissue morphogenesis, ! interaction with host GO:0051701 11 11 0,000 0,07118653 0,11034211 ! membrane depolarization GO:0051899 11 11 0,000 0,07118653 0,11024939 ! regulation of interleukin-2 production GO:0032663 11 11 0,000 0,07118653 0,11015682 ! regulation of ARF GTPase activity GO:0032312 11 11 0,000 0,07118653 0,11006441 ! oogenesis GO:0048477 11 11 0,000 0,07118653 0,10997215 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 11 11 0,000 0,07118653 0,10988004 ! regulation of cellular carbohydrate metabolic process GO:0010675 11 11 0,000 0,07118653 0,10978809 GO:0006109|regulation of carbohydrate metabolic process, ! vitamin transport GO:0051180 11 11 0,000 0,07118653 0,1096963 ! muscle maintenance GO:0046716 12 11 0,000 0,07118653 0,10960466 ! vitamin A metabolic process GO:0006776 11 11 0,000 0,07118653 0,10951317 ! steroid catabolic process GO:0006706 11 11 0,000 0,07118653 0,10942183 ! endocrine process GO:0050886 11 11 0,000 0,07118653 0,10933064 GO:0001990|regulation of systemic arterial blood pressure by hormone, ! aromatic amino acid family metabolic process GO:0009072 11 11 0,000 0,07118653 0,10923961 ! proximal/distal pattern formation GO:0009954 11 11 0,000 0,07118653 0,10914873 ! somatic diversification of immunoglobulins GO:0016445 11 11 0,000 0,07118653 0,109058 ! RNA 3'-end processing GO:0031123 11 11 0,000 0,07118653 0,10896742 ! polysaccharide metabolic process GO:0005976 69 66 1,000 0,07163826 0,10956789 ! Golgi vesicle transport GO:0048193 67 67 1,000 0,07353663 0,11237812 ! response to radiation GO:0009314 70 68 1,000 0,07545132 0,11520861 ! regulation of cell size GO:0008361 68 68 1,000 0,07545132 0,11511323 ! regulation of translation GO:0006417 69 69 1,000 0,07738204 0,11796121 ! response to nutrient levels GO:0031667 69 69 1,000 0,07738204 0,11786372 ! translational initiation GO:0006413 12 12 0,000 0,07740656 0,11780371 ! positive regulation of angiogenesis GO:0045766 12 12 0,000 0,07740656 0,11770652 ! initiation of viral infection GO:0019059 12 12 0,000 0,07740656 0,11760948 ! DNA catabolic process, endonucleolytic GO:0000737 12 12 0,000 0,07740656 0,1175126 ! iron ion transport GO:0006826 13 12 0,000 0,07740656 0,11741588 ! phosphatidylcholine metabolic process GO:0046470 12 12 0,000 0,07740656 0,11731932 ! amino sugar metabolic process GO:0006040 12 12 0,000 0,07740656 0,11722292 ! post-Golgi vesicle-mediated transport GO:0006892 12 12 0,000 0,07740656 0,11712668 ! protein amino acid ADP-ribosylation GO:0006471 12 12 0,000 0,07740656 0,1170306 ! heterophilic cell adhesion GO:0007157 12 12 0,000 0,07740656 0,11693467 ! collagen metabolic process GO:0032963 12 12 0,000 0,07740656 0,1168389 ! hindlimb morphogenesis GO:0035137 12 12 0,000 0,07740656 0,11674329 ! xenobiotic metabolic process GO:0006805 12 12 0,000 0,07740656 0,11664783 ! glutamate signaling pathway GO:0007215 12 12 0,000 0,07740656 0,11655253 ! C21-steroid hormone metabolic process GO:0008207 13 12 0,000 0,07740656 0,11645739 ! regulation of muscle cell differentiation GO:0051147 13 12 0,000 0,07740656 0,1163624 ! cellular response to hydrogen peroxide GO:0070301 12 12 0,000 0,07740656 0,11626756 GO:0042744|hydrogen peroxide catabolic process, ! negative regulation of peptidase activity GO:0010466 12 12 0,000 0,07740656 0,11617288 ! actomyosin structure organization GO:0031032 12 12 0,000 0,07740656 0,11607835 ! microtubule organizing center organization GO:0031023 12 12 0,000 0,07740656 0,11598398 GO:0051297|centrosome organization, ! positive regulation of endocytosis GO:0045807 12 12 0,000 0,07740656 0,11588976 ! retinoid metabolic process GO:0001523 12 12 0,000 0,07740656 0,1157957 GO:0016101|diterpenoid metabolic process, ! mitotic chromosome condensation GO:0007076 12 12 0,000 0,07740656 0,11570178 ! positive regulation of innate immune response GO:0045089 12 12 0,000 0,07740656 0,11560802 ! GPI anchor biosynthetic process GO:0006506 12 12 0,000 0,07740656 0,11551441 GO:0006505|GPI anchor metabolic process, ! deoxyribonucleotide catabolic process GO:0009264 12 12 0,000 0,07740656 0,11542095 ! vacuolar transport GO:0007034 12 12 0,000 0,07740656 0,11532765 ! polysaccharide catabolic process GO:0000272 12 12 0,000 0,07740656 0,11523449 ! vesicle docking during exocytosis GO:0006904 12 12 0,000 0,07740656 0,11514148 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 12 12 0,000 0,07740656 0,11504863 ! barbed-end actin filament capping GO:0051016 12 12 0,000 0,07740656 0,11495592 GO:0051693|actin filament capping, ! male gonad development GO:0008584 12 12 0,000 0,07740656 0,11486336 ! regulation of insulin secretion GO:0050796 12 12 0,000 0,07740656 0,11477096 ! renal system process GO:0003014 12 12 0,000 0,07740656 0,1146787 ! regulation of tumor necrosis factor production GO:0032680 12 12 0,000 0,07740656 0,11458658 ! regulation of steroid metabolic process GO:0019218 12 12 0,000 0,07740656 0,11449462 ! pallium development GO:0021543 13 12 0,000 0,07740656 0,1144028 ! cell fate determination GO:0001709 12 12 0,000 0,07740656 0,11431114 ! positive regulation of multicellular organism growth GO:0040018 12 12 0,000 0,07740656 0,11421961 ! regulation of response to biotic stimulus GO:0002831 12 12 0,000 0,07740656 0,11412824 ! positive regulation of adaptive immune response GO:0002821 12 12 0,000 0,07740656 0,11403701 ! detection of light stimulus GO:0009583 13 12 0,000 0,07740656 0,11394592 ! synaptogenesis GO:0007416 12 12 0,000 0,07740656 0,11385499 ! fat-soluble vitamin metabolic process GO:0006775 12 12 0,000 0,07740656 0,11376419 ! neurotransmitter secretion GO:0007269 14 12 0,000 0,07740656 0,11367354 ! heme biosynthetic process GO:0006783 12 12 0,000 0,07740656 0,11358304 ! spermatid differentiation GO:0048515 13 12 0,000 0,07740656 0,11349268 GO:0007286|spermatid development, ! aromatic compound catabolic process GO:0019439 13 12 0,000 0,07740656 0,11340246 ! pyrimidine nucleotide biosynthetic process GO:0006221 12 12 0,000 0,07740656 0,11331239 ! neural tube closure GO:0001843 13 12 0,000 0,07740656 0,11322246 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! negative regulation of translation GO:0017148 12 12 0,000 0,07740656 0,11313267 ! regulation of microtubule polymerization or depolymerization GO:0031110 12 12 0,000 0,07740656 0,11304302 ! cellular monovalent inorganic cation homeostasis GO:0030004 12 12 0,000 0,07740656 0,11295352 ! calcium ion homeostasis GO:0055074 71 71 1,000 0,0812904 0,11852706 GO:0006874|cellular calcium ion homeostasis, ! positive regulation of hydrolase activity GO:0051345 72 72 1,000 0,08326747 0,12131379 ! response to extracellular stimulus GO:0009991 72 72 1,000 0,08326747 0,12121797 ! regulation of cytokine production GO:0001817 72 72 1,000 0,08326747 0,1211223 ! positive regulation of DNA replication GO:0045740 14 13 0,000 0,08358584 0,12148952 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 13 13 0,000 0,08358584 0,12139378 GO:0016444|somatic cell DNA recombination, ! negative regulation of actin filament polymerization GO:0030837 13 13 0,000 0,08358584 0,1212982 ! phenol metabolic process GO:0018958 13 13 0,000 0,08358584 0,12120276 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, GO:0009712|catechol metabolic process, ! G2/M transition of mitotic cell cycle GO:0000086 13 13 0,000 0,08358584 0,12110748 ! gluconeogenesis GO:0006094 13 13 0,000 0,08358584 0,12101234 ! 2'-deoxyribonucleotide metabolic process GO:0009394 13 13 0,000 0,08358584 0,12091736 GO:0019692|deoxyribose phosphate metabolic process, ! intra-Golgi vesicle-mediated transport GO:0006891 13 13 0,000 0,08358584 0,12082252 ! glycosaminoglycan biosynthetic process GO:0006024 13 13 0,000 0,08358584 0,12072783 ! regeneration GO:0031099 13 13 0,000 0,08358584 0,12063329 ! keratinization GO:0031424 13 13 0,000 0,08358584 0,1205389 ! post-embryonic development GO:0009791 14 13 0,000 0,08358584 0,12044465 ! negative regulation of protein modification process GO:0031400 13 13 0,000 0,08358584 0,12035056 ! patterning of blood vessels GO:0001569 13 13 0,000 0,08358584 0,12025661 ! regulation of innate immune response GO:0045088 13 13 0,000 0,08358584 0,1201628 ! mitochondrial membrane organization GO:0007006 13 13 0,000 0,08358584 0,12006914 ! negative regulation of DNA replication GO:0008156 13 13 0,000 0,08358584 0,11997563 ! multicellular organismal macromolecule metabolic process GO:0044259 13 13 0,000 0,08358584 0,11988227 ! multicellular organismal catabolic process GO:0044243 13 13 0,000 0,08358584 0,11978904 ! autophagy GO:0006914 13 13 0,000 0,08358584 0,11969597 ! receptor metabolic process GO:0043112 14 13 0,000 0,08358584 0,11960304 ! negative regulation of protein catabolic process GO:0042177 13 13 0,000 0,08358584 0,11951025 ! ureteric bud development GO:0001657 13 13 0,000 0,08358584 0,11941761 ! cell aging GO:0007569 13 13 0,000 0,08358584 0,11932511 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 13 13 0,000 0,08358584 0,11923275 ! negative regulation of protein kinase cascade GO:0010741 13 13 0,000 0,08358584 0,11914053 ! purine nucleoside monophosphate metabolic process GO:0009126 13 13 0,000 0,08358584 0,11904846 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of peptide secretion GO:0002791 13 13 0,000 0,08358584 0,11895653 ! regulation of viral reproduction GO:0050792 13 13 0,000 0,08358584 0,11886475 ! nucleobase metabolic process GO:0009112 13 13 0,000 0,08358584 0,1187731 ! regulation of axonogenesis GO:0050770 14 13 0,000 0,08358584 0,1186816 ! positive regulation of neurogenesis GO:0050769 13 13 0,000 0,08358584 0,11859023 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 14 13 0,000 0,08358584 0,11849901 ! vasodilation GO:0042311 14 13 0,000 0,08358584 0,11840793 ! positive regulation of leukocyte mediated immunity GO:0002705 13 13 0,000 0,08358584 0,11831698 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 13 13 0,000 0,08358584 0,11822618 ! glycosphingolipid metabolic process GO:0006687 13 13 0,000 0,08358584 0,11813551 GO:0006664|glycolipid metabolic process, ! neural crest cell migration GO:0001755 14 13 0,000 0,08358584 0,11804499 ! neutrophil chemotaxis GO:0030593 14 13 0,000 0,08358584 0,1179546 ! long-chain fatty acid transport GO:0015909 13 13 0,000 0,08358584 0,11786435 ! immunoglobulin production GO:0002377 13 13 0,000 0,08358584 0,11777424 GO:0002440|production of molecular mediator of immune response, ! negative regulation of Wnt receptor signaling pathway GO:0030178 13 13 0,000 0,08358584 0,11768427 ! regulation of cell-substrate adhesion GO:0010810 14 13 0,000 0,08358584 0,11759444 GO:0001952|regulation of cell-matrix adhesion, ! negative regulation of myeloid cell differentiation GO:0045638 13 13 0,000 0,08358584 0,11750474 ! response to cytokine stimulus GO:0034097 13 13 0,000 0,08358584 0,11741518 ! activation of JUN kinase activity GO:0007257 13 13 0,000 0,08358584 0,11732575 ! terpenoid metabolic process GO:0006721 13 13 0,000 0,08358584 0,11723646 ! alkene biosynthetic process GO:0043450 13 13 0,000 0,08358584 0,11714731 GO:0019370|leukotriene biosynthetic process, ! purine nucleotide catabolic process GO:0006195 13 13 0,000 0,08358584 0,11705829 ! porphyrin biosynthetic process GO:0006779 13 13 0,000 0,08358584 0,11696941 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of cytokine production GO:0001818 13 13 0,000 0,08358584 0,11688066 ! camera-type eye morphogenesis GO:0048593 13 13 0,000 0,08358584 0,11679205 ! pyrimidine nucleoside metabolic process GO:0006213 13 13 0,000 0,08358584 0,11670357 ! telomere organization GO:0032200 13 13 0,000 0,08358584 0,11661522 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 13 13 0,000 0,08358584 0,11652701 ! regulation of amine transport GO:0051952 13 13 0,000 0,08358584 0,11643894 ! inner ear receptor cell differentiation GO:0060113 13 13 0,000 0,08358584 0,11635099 ! protein tetramerization GO:0051262 13 13 0,000 0,08358584 0,11626318 ! coenzyme metabolic process GO:0006732 75 74 1,000 0,087266 0,12129053 ! neuron fate commitment GO:0048663 14 14 0,000 0,08972463 0,12461379 ! sulfur amino acid metabolic process GO:0000096 14 14 0,000 0,08972463 0,12451995 ! regulation of interferon-gamma production GO:0032649 14 14 0,000 0,08972463 0,12442626 ! pyruvate metabolic process GO:0006090 14 14 0,000 0,08972463 0,1243327 ! cellular aldehyde metabolic process GO:0006081 14 14 0,000 0,08972463 0,12423929 ! cellular iron ion homeostasis GO:0006879 14 14 0,000 0,08972463 0,12414602 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 14 14 0,000 0,08972463 0,12405289 ! regulation of neuron projection development GO:0010975 15 14 0,000 0,08972463 0,12395989 ! protein amino acid deacetylation GO:0006476 14 14 0,000 0,08972463 0,12386704 ! aminoglycan biosynthetic process GO:0006023 14 14 0,000 0,08972463 0,12377432 ! vesicle docking GO:0048278 14 14 0,000 0,08972463 0,12368175 ! superoxide metabolic process GO:0006801 15 14 0,000 0,08972463 0,12358931 ! macromolecular complex disassembly GO:0032984 15 14 0,000 0,08972463 0,12349701 ! calcium-dependent cell-cell adhesion GO:0016339 14 14 0,000 0,08972463 0,12340485 ! mechanoreceptor differentiation GO:0042490 14 14 0,000 0,08972463 0,12331282 ! isoprenoid biosynthetic process GO:0008299 14 14 0,000 0,08972463 0,12322094 ! hair cycle GO:0042633 14 14 0,000 0,08972463 0,12312919 GO:0022404|molting cycle process, GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042303|molting cycle, ! negative regulation of epithelial cell proliferation GO:0050680 14 14 0,000 0,08972463 0,12303757 ! immune response-activating cell surface receptor signaling pathway GO:0002429 14 14 0,000 0,08972463 0,12294609 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! multicellular organismal response to stress GO:0033555 14 14 0,000 0,08972463 0,12285475 ! lysosome organization GO:0007040 14 14 0,000 0,08972463 0,12276355 ! actin polymerization or depolymerization GO:0008154 15 14 0,000 0,08972463 0,12267247 ! D-ribose metabolic process GO:0006014 14 14 0,000 0,08972463 0,12258154 ! negative regulation of phosphorus metabolic process GO:0010563 14 14 0,000 0,08972463 0,12249074 GO:0045936|negative regulation of phosphate metabolic process, ! primary neural tube formation GO:0014020 15 14 0,000 0,08972463 0,12240007 ! peptide cross-linking GO:0018149 14 14 0,000 0,08972463 0,12230954 ! vitamin biosynthetic process GO:0009110 14 14 0,000 0,08972463 0,12221914 ! response to organic cyclic substance GO:0014070 15 14 0,000 0,08972463 0,12212887 ! leukotriene metabolic process GO:0006691 14 14 0,000 0,08972463 0,12203874 ! regulation of vasoconstriction GO:0019229 14 14 0,000 0,08972463 0,12194874 ! formation of primary germ layer GO:0001704 14 14 0,000 0,08972463 0,12185888 GO:0001707|mesoderm formation, ! DNA modification GO:0006304 14 14 0,000 0,08972463 0,12176914 ! collagen fibril organization GO:0030199 14 14 0,000 0,08972463 0,12167954 ! proteoglycan biosynthetic process GO:0030166 14 14 0,000 0,08972463 0,12159007 ! regulation of blood coagulation GO:0030193 15 14 0,000 0,08972463 0,12150073 ! group transfer coenzyme metabolic process GO:0006752 14 14 0,000 0,08972463 0,12141152 ! neuromuscular process controlling balance GO:0050885 14 14 0,000 0,08972463 0,12132245 ! aspartate family amino acid metabolic process GO:0009066 14 14 0,000 0,08972463 0,1212335 ! negative regulation of protein polymerization GO:0032272 14 14 0,000 0,08972463 0,12114469 ! positive regulation of multicellular organismal process GO:0051240 76 76 1,000 0,09132189 0,12321101 ! cellular metal ion homeostasis GO:0006875 77 77 1,000 0,09337066 0,12588305 ! microtubule-based movement GO:0007018 82 78 1,000 0,09543297 0,12856942 ! positive regulation of protein kinase cascade GO:0010740 79 78 1,000 0,09543297 0,1284755 ! metal ion homeostasis GO:0055065 78 78 1,000 0,09543297 0,12838173 ! regulation of immune response GO:0050776 78 78 1,000 0,09543297 0,12828809 ! protein import into nucleus, translocation GO:0000060 15 15 0,000 0,09582318 0,12871875 ! positive regulation of fibroblast proliferation GO:0048146 15 15 0,000 0,09582318 0,128625 ! negative regulation of actin filament depolymerization GO:0030835 15 15 0,000 0,09582318 0,12853139 ! positive regulation of ossification GO:0045778 15 15 0,000 0,09582318 0,12843791 GO:0046852|positive regulation of bone remodeling, GO:0034105|positive regulation of tissue remodeling, ! protein amino acid O-linked glycosylation GO:0006493 15 15 0,000 0,09582318 0,12834457 ! cellular polysaccharide biosynthetic process GO:0033692 15 15 0,000 0,09582318 0,12825136 ! proteoglycan metabolic process GO:0006029 15 15 0,000 0,09582318 0,12815829 ! regulation of transcription factor import into nucleus GO:0042990 15 15 0,000 0,09582318 0,12806536 ! odontogenesis of dentine-containing tooth GO:0042475 15 15 0,000 0,09582318 0,12797256 ! detection of stimulus involved in sensory perception GO:0050906 16 15 0,000 0,09582318 0,12787989 ! ovarian follicle development GO:0001541 15 15 0,000 0,09582318 0,12778736 ! antigen processing and presentation of peptide antigen GO:0048002 15 15 0,000 0,09582318 0,12769496 ! regulation of smooth muscle contraction GO:0006940 15 15 0,000 0,09582318 0,12760269 ! deoxyribonucleotide metabolic process GO:0009262 15 15 0,000 0,09582318 0,12751056 ! complement activation, classical pathway GO:0006958 15 15 0,000 0,09582318 0,12741856 ! heme metabolic process GO:0042168 15 15 0,000 0,09582318 0,1273267 ! mesoderm morphogenesis GO:0048332 15 15 0,000 0,09582318 0,12723496 ! chromosome condensation GO:0030261 15 15 0,000 0,09582318 0,12714336 ! response to starvation GO:0042594 15 15 0,000 0,09582318 0,12705189 ! response to ionizing radiation GO:0010212 16 15 0,000 0,09582318 0,12696055 ! response to mechanical stimulus GO:0009612 15 15 0,000 0,09582318 0,12686935 ! hydrogen peroxide metabolic process GO:0042743 15 15 0,000 0,09582318 0,12677827 ! regulation of biomineral formation GO:0070167 15 15 0,000 0,09582318 0,12668732 GO:0030500|regulation of bone mineralization, ! cyclic nucleotide biosynthetic process GO:0009190 15 15 0,000 0,09582318 0,12659651 ! phospholipid transport GO:0015914 15 15 0,000 0,09582318 0,12650582 ! regulation of cytokine secretion GO:0050707 15 15 0,000 0,09582318 0,12641527 ! glutathione metabolic process GO:0006749 16 15 0,000 0,09582318 0,12632484 ! nicotinamide metabolic process GO:0006769 15 15 0,000 0,09582318 0,12623455 GO:0046496|nicotinamide nucleotide metabolic process, ! cellular alkene metabolic process GO:0043449 15 15 0,000 0,09582318 0,12614438 ! somatic diversification of immune receptors GO:0002200 15 15 0,000 0,09582318 0,12605434 ! positive regulation of immune effector process GO:0002699 15 15 0,000 0,09582318 0,12596443 ! nuclear transport GO:0051169 79 79 1,000 0,09750855 0,12808856 GO:0006913|nucleocytoplasmic transport, ! negative regulation of adenylate cyclase activity GO:0007194 16 16 0,000 0,10188176 0,13373795 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! alkaloid metabolic process GO:0009820 16 16 0,000 0,10188176 0,13364277 ! regulation of synaptic plasticity GO:0048167 16 16 0,000 0,10188176 0,13354772 ! spliceosomal snRNP biogenesis GO:0000387 16 16 0,000 0,10188176 0,1334528 ! learning GO:0007612 16 16 0,000 0,10188176 0,13335802 ! circadian rhythm GO:0007623 16 16 0,000 0,10188176 0,13326337 ! inner ear morphogenesis GO:0042472 16 16 0,000 0,10188176 0,13316886 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 16 16 0,000 0,10188176 0,13307448 ! vacuole organization GO:0007033 16 16 0,000 0,10188176 0,13298023 ! cellular response to reactive oxygen species GO:0034614 16 16 0,000 0,10188176 0,13288612 ! positive regulation of cytoskeleton organization GO:0051495 16 16 0,000 0,10188176 0,13279214 ! fatty acid beta-oxidation GO:0006635 16 16 0,000 0,10188176 0,1326983 ! triglyceride metabolic process GO:0006641 16 16 0,000 0,10188176 0,13260458 ! iron ion homeostasis GO:0055072 16 16 0,000 0,10188176 0,132511 ! positive regulation of cell development GO:0010720 16 16 0,000 0,10188176 0,13241755 ! lymphocyte proliferation GO:0046651 16 16 0,000 0,10188176 0,13232423 ! regulation of systemic arterial blood pressure GO:0003073 17 16 0,000 0,10188176 0,13223105 ! cell fate specification GO:0001708 16 16 0,000 0,10188176 0,13213799 ! pentose metabolic process GO:0019321 16 16 0,000 0,10188176 0,13204507 ! fatty acid transport GO:0015908 16 16 0,000 0,10188176 0,13195228 ! cellular response to nutrient levels GO:0031669 16 16 0,000 0,10188176 0,13185961 ! regulation of microtubule cytoskeleton organization GO:0070507 16 16 0,000 0,10188176 0,13176708 ! ethanolamine and derivative metabolic process GO:0042439 17 16 0,000 0,10188176 0,13167468 ! polyol metabolic process GO:0019751 16 16 0,000 0,10188176 0,1315824 ! serine family amino acid metabolic process GO:0009069 16 16 0,000 0,10188176 0,13149026 ! glutamine family amino acid catabolic process GO:0009065 17 16 0,000 0,10188176 0,13139824 ! porphyrin metabolic process GO:0006778 16 16 0,000 0,10188176 0,13130635 GO:0033013|tetrapyrrole metabolic process, ! embryonic epithelial tube formation GO:0001838 17 16 0,000 0,10188176 0,1312146 GO:0001841|neural tube formation, ! regulation of JUN kinase activity GO:0043506 17 16 0,000 0,10188176 0,13112297 GO:0043507|positive regulation of JUN kinase activity, ! regulation of cell morphogenesis involved in differentiation GO:0010769 17 16 0,000 0,10188176 0,13103146 ! response to xenobiotic stimulus GO:0009410 16 16 0,000 0,10188176 0,13094009 ! regulation of coagulation GO:0050818 17 16 0,000 0,10188176 0,13084884 ! regulation of fibroblast proliferation GO:0048145 17 17 0,000 0,10790062 0,13848248 ! regulation of actin filament depolymerization GO:0030834 17 17 0,000 0,10790062 0,13838611 ! phosphoinositide biosynthetic process GO:0046489 17 17 0,000 0,10790062 0,13828988 ! regulation of transmembrane transport GO:0034762 17 17 0,000 0,10790062 0,13819377 ! nucleotide-excision repair, DNA damage removal GO:0000718 18 17 0,000 0,10790062 0,13809781 ! leukocyte adhesion GO:0007159 17 17 0,000 0,10790062 0,13800197 ! dicarboxylic acid metabolic process GO:0043648 18 17 0,000 0,10790062 0,13790627 ! sensory perception of smell GO:0007608 17 17 0,000 0,10790062 0,1378107 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 17 17 0,000 0,10790062 0,13771526 ! cellular carbohydrate biosynthetic process GO:0034637 17 17 0,000 0,10790062 0,13761996 ! development of primary male sexual characteristics GO:0046546 17 17 0,000 0,10790062 0,13752479 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 17 17 0,000 0,10790062 0,13742975 ! neural crest cell development GO:0014032 19 17 0,000 0,10790062 0,13733484 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 18 17 0,000 0,10790062 0,13724006 ! negative regulation of cell development GO:0010721 18 17 0,000 0,10790062 0,13714541 GO:0050768|negative regulation of neurogenesis, ! immune response-activating signal transduction GO:0002757 17 17 0,000 0,10790062 0,13705089 GO:0002764|immune response-regulating signal transduction, ! cell recognition GO:0008037 18 17 0,000 0,10790062 0,1369565 ! pyridine nucleotide metabolic process GO:0019362 17 17 0,000 0,10790062 0,13686225 ! pigmentation GO:0043473 17 17 0,000 0,10790062 0,13676812 ! myeloid leukocyte activation GO:0002274 18 17 0,000 0,10790062 0,13667412 ! adult locomotory behavior GO:0008344 17 17 0,000 0,10790062 0,13658025 ! embryonic organ development GO:0048568 17 17 0,000 0,10790062 0,13648651 ! regulation of calcium ion transport GO:0051924 17 17 0,000 0,10790062 0,1363929 ! liver development GO:0001889 17 17 0,000 0,10790062 0,13629941 ! gene silencing GO:0016458 17 17 0,000 0,10790062 0,13620606 ! hexose metabolic process GO:0019318 87 86 1,000 0,11238763 0,14177303 ! mRNA export from nucleus GO:0006406 18 18 0,000 0,11388001 0,14355736 ! regulation of cellular catabolic process GO:0031329 18 18 0,000 0,11388001 0,14345924 ! icosanoid biosynthetic process GO:0046456 18 18 0,000 0,11388001 0,14336125 ! regulation of metal ion transport GO:0010959 18 18 0,000 0,11388001 0,14326339 ! membrane docking GO:0022406 18 18 0,000 0,11388001 0,14316566 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 18 18 0,000 0,11388001 0,14306807 ! mononuclear cell proliferation GO:0032943 18 18 0,000 0,11388001 0,14297061 GO:0070661|leukocyte proliferation, ! response to calcium ion GO:0051592 18 18 0,000 0,11388001 0,14287329 ! negative regulation of response to external stimulus GO:0032102 18 18 0,000 0,11388001 0,1427761 ! cholesterol homeostasis GO:0042632 18 18 0,000 0,11388001 0,14267904 GO:0055092|sterol homeostasis, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 18 18 0,000 0,11388001 0,14258211 ! striated muscle contraction GO:0006941 18 18 0,000 0,11388001 0,14248531 ! neutral lipid metabolic process GO:0006638 18 18 0,000 0,11388001 0,14238865 GO:0006639|acylglycerol metabolic process, ! ceramide metabolic process GO:0006672 18 18 0,000 0,11388001 0,14229211 GO:0046519|sphingoid metabolic process, ! ribonucleoside monophosphate metabolic process GO:0009161 18 18 0,000 0,11388001 0,14219571 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! telencephalon development GO:0021537 19 18 0,000 0,11388001 0,14209943 ! hexose biosynthetic process GO:0019319 18 18 0,000 0,11388001 0,14200329 ! negative regulation of MAP kinase activity GO:0043407 18 18 0,000 0,11388001 0,14190728 ! B cell differentiation GO:0030183 18 18 0,000 0,11388001 0,14181139 ! cellular response to extracellular stimulus GO:0031668 18 18 0,000 0,11388001 0,14171564 ! regulation of microtubule-based process GO:0032886 18 18 0,000 0,11388001 0,14162002 ! negative regulation of catabolic process GO:0009895 18 18 0,000 0,11388001 0,14152452 ! symbiosis, encompassing mutualism through parasitism GO:0044403 18 18 0,000 0,11388001 0,14142915 ! chemotaxis GO:0006935 90 89 1,000 0,11893828 0,14761161 GO:0042330|taxis, ! cellular di-, tri-valent inorganic cation homeostasis GO:0030005 89 89 1,000 0,11893828 0,14751228 ! activation of adenylate cyclase activity GO:0007190 19 19 0,000 0,11982019 0,14850613 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 19 19 0,000 0,11982019 0,14840633 GO:0006956|complement activation, ! negative regulation of DNA metabolic process GO:0051053 19 19 0,000 0,11982019 0,14830666 ! glial cell differentiation GO:0010001 19 19 0,000 0,11982019 0,14820712 ! regulation of pH GO:0006885 19 19 0,000 0,11982019 0,14810772 ! feeding behavior GO:0007631 19 19 0,000 0,11982019 0,14800846 ! peroxisome organization GO:0007031 19 19 0,000 0,11982019 0,14790932 ! regulation of striated muscle tissue development GO:0016202 20 19 0,000 0,11982019 0,14781032 ! multicellular organismal metabolic process GO:0044236 19 19 0,000 0,11982019 0,14771145 ! peptidyl-tyrosine phosphorylation GO:0018108 20 19 0,000 0,11982019 0,14761271 ! metanephros development GO:0001656 19 19 0,000 0,11982019 0,14751411 ! ribonucleoside metabolic process GO:0009119 19 19 0,000 0,11982019 0,14741563 ! cellular response to oxidative stress GO:0034599 19 19 0,000 0,11982019 0,14731729 ! regulation of lymphocyte mediated immunity GO:0002706 19 19 0,000 0,11982019 0,14721908 ! nuclear-transcribed mRNA catabolic process GO:0000956 19 19 0,000 0,11982019 0,147121 ! regulation of protein stability GO:0031647 19 19 0,000 0,11982019 0,14702305 ! hormone biosynthetic process GO:0042446 19 19 0,000 0,11982019 0,14692523 ! biogenic amine biosynthetic process GO:0042401 20 19 0,000 0,11982019 0,14682754 ! eye morphogenesis GO:0048592 19 19 0,000 0,11982019 0,14672998 ! response to heat GO:0009408 19 19 0,000 0,11982019 0,14663255 ! regulation of Ras protein signal transduction GO:0046578 90 90 1,000 0,12114325 0,14815329 ! brain development GO:0007420 91 90 1,000 0,12114325 0,14805505 ! di-, tri-valent inorganic cation homeostasis GO:0055066 91 91 1,000 0,12335855 0,15066256 ! regulation of muscle development GO:0048634 21 20 0,000 0,12572141 0,15344673 ! negative regulation of cell adhesion GO:0007162 21 20 0,000 0,12572141 0,15334518 ! organic ether metabolic process GO:0018904 20 20 0,000 0,12572141 0,15324376 GO:0006662|glycerol ether metabolic process, ! cytoskeleton-dependent intracellular transport GO:0030705 20 20 0,000 0,12572141 0,15314247 ! neural tube development GO:0021915 21 20 0,000 0,12572141 0,15304132 ! nucleus organization GO:0006997 20 20 0,000 0,12572141 0,15294031 ! phagocytosis GO:0006909 21 20 0,000 0,12572141 0,15283942 ! positive regulation of gene-specific transcription GO:0043193 20 20 0,000 0,12572141 0,15273867 ! unsaturated fatty acid biosynthetic process GO:0006636 20 20 0,000 0,12572141 0,15263805 ! protein targeting to membrane GO:0006612 22 20 0,000 0,12572141 0,15253757 ! cyclic nucleotide metabolic process GO:0009187 20 20 0,000 0,12572141 0,15243721 ! chromatin remodeling GO:0006338 20 20 0,000 0,12572141 0,15233699 ! detection of abiotic stimulus GO:0009582 21 20 0,000 0,12572141 0,1522369 ! peptidyl-tyrosine modification GO:0018212 21 20 0,000 0,12572141 0,15213694 ! lipid oxidation GO:0034440 20 20 0,000 0,12572141 0,15203712 GO:0019395|fatty acid oxidation, ! female gamete generation GO:0007292 20 20 0,000 0,12572141 0,15193742 ! negative regulation of neuron apoptosis GO:0043524 21 20 0,000 0,12572141 0,15183785 ! monosaccharide biosynthetic process GO:0046364 20 20 0,000 0,12572141 0,15173842 ! RNA modification GO:0009451 20 20 0,000 0,12572141 0,15163911 ! tissue morphogenesis GO:0048729 94 93 1,000 0,12781922 0,15406856 ! regulation of response to stress GO:0080134 97 94 1,000 0,13006414 0,15667203 ! epidermis development GO:0008544 94 94 1,000 0,13006414 0,1565697 ! cofactor metabolic process GO:0051186 95 94 1,000 0,13006414 0,1564675 ! mRNA catabolic process GO:0006402 21 21 0,000 0,13158392 0,15819254 ! positive regulation of adenylate cyclase activity GO:0045762 21 21 0,000 0,13158392 0,15808942 GO:0051349|positive regulation of lyase activity, GO:0031281|positive regulation of cyclase activity, ! protein amino acid lipidation GO:0006497 21 21 0,000 0,13158392 0,15798643 ! receptor-mediated endocytosis GO:0006898 21 21 0,000 0,13158392 0,15788357 ! morphogenesis of embryonic epithelium GO:0016331 22 21 0,000 0,13158392 0,15778085 ! ear morphogenesis GO:0042471 21 21 0,000 0,13158392 0,15767826 ! organic anion transport GO:0015711 21 21 0,000 0,13158392 0,15757581 ! cholesterol transport GO:0030301 21 21 0,000 0,13158392 0,15747349 GO:0015918|sterol transport, ! spliceosome assembly GO:0000245 22 21 0,000 0,13158392 0,1573713 ! regulation of Rab protein signal transduction GO:0032483 21 21 0,000 0,13158392 0,15726924 GO:0032313|regulation of Rab GTPase activity, ! regulation of protein import into nucleus GO:0042306 21 21 0,000 0,13158392 0,15716732 ! regulation of leukocyte mediated immunity GO:0002703 21 21 0,000 0,13158392 0,15706552 ! regulation of multicellular organism growth GO:0040014 21 21 0,000 0,13158392 0,15696386 ! regulation of proteolysis GO:0030162 21 21 0,000 0,13158392 0,15686233 ! negative regulation of hydrolase activity GO:0051346 21 21 0,000 0,13158392 0,15676094 ! RNA export from nucleus GO:0006405 22 22 0,000 0,13740797 0,1635936 ! cellular amide metabolic process GO:0043603 22 22 0,000 0,13740797 0,16348798 ! regulation of ion transport GO:0043269 22 22 0,000 0,13740797 0,16338251 ! odontogenesis GO:0042476 22 22 0,000 0,13740797 0,16327717 ! hormone-mediated signaling GO:0009755 22 22 0,000 0,13740797 0,16317196 ! maintenance of protein location in cell GO:0032507 23 22 0,000 0,13740797 0,1630669 ! ovulation cycle process GO:0022602 22 22 0,000 0,13740797 0,16296196 ! pigment biosynthetic process GO:0046148 22 22 0,000 0,13740797 0,16285716 ! respiratory gaseous exchange GO:0007585 22 22 0,000 0,13740797 0,1627525 ! biopolymer methylation GO:0043414 22 22 0,000 0,13740797 0,16264797 GO:0032259|methylation, ! detection of external stimulus GO:0009581 23 22 0,000 0,13740797 0,16254357 ! neuron migration GO:0001764 22 22 0,000 0,13740797 0,16243931 ! regulation of Wnt receptor signaling pathway GO:0030111 23 22 0,000 0,13740797 0,16233518 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 22 22 0,000 0,13740797 0,16223119 ! fatty acid catabolic process GO:0009062 23 22 0,000 0,13740797 0,16212733 ! cytokine production GO:0001816 22 22 0,000 0,13740797 0,1620236 ! pyrimidine nucleotide metabolic process GO:0006220 22 22 0,000 0,13740797 0,16192001 ! ectoderm development GO:0007398 99 99 1,000 0,14142578 0,16654806 ! response to hydrogen peroxide GO:0042542 24 23 0,000 0,1431938 0,16852246 ! epithelial cell differentiation GO:0030855 23 23 0,000 0,1431938 0,16841492 ! viral infectious cycle GO:0019058 23 23 0,000 0,1431938 0,16830751 ! response to estrogen stimulus GO:0043627 23 23 0,000 0,1431938 0,16820024 ! negative regulation of protein complex disassembly GO:0043242 23 23 0,000 0,1431938 0,16809311 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 23 23 0,000 0,1431938 0,16798611 ! induction of apoptosis by extracellular signals GO:0008624 23 23 0,000 0,1431938 0,16787925 ! regulation of ARF protein signal transduction GO:0032012 23 23 0,000 0,1431938 0,16777252 ! lipoprotein biosynthetic process GO:0042158 23 23 0,000 0,1431938 0,16766593 ! positive regulation of growth GO:0045927 23 23 0,000 0,1431938 0,16755948 ! female gonad development GO:0008585 23 23 0,000 0,1431938 0,16745316 ! monovalent inorganic cation homeostasis GO:0055067 23 23 0,000 0,1431938 0,16734697 ! lipid homeostasis GO:0055088 23 23 0,000 0,1431938 0,16724092 ! Rho protein signal transduction GO:0007266 24 23 0,000 0,1431938 0,16713501 ! regulation of JNK cascade GO:0046328 25 23 0,000 0,1431938 0,16702923 ! negative regulation of transcription from RNA polymerase II promoter GO:0000122 103 100 1,000 0,14372402 0,16754167 ! response to other organism GO:0051707 101 100 1,000 0,14372402 0,16743576 ! mitochondrial transport GO:0006839 24 24 0,000 0,14894166 0,1734046 ! gliogenesis GO:0042063 24 24 0,000 0,14894166 0,17329513 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 26 24 0,000 0,14894166 0,17318579 ! cellular amino acid biosynthetic process GO:0008652 24 24 0,000 0,14894166 0,1730766 ! glucose homeostasis GO:0042593 24 24 0,000 0,14894166 0,17296754 GO:0033500|carbohydrate homeostasis, ! heterocycle biosynthetic process GO:0018130 24 24 0,000 0,14894166 0,17285862 ! T cell differentiation GO:0030217 24 24 0,000 0,14894166 0,17274983 ! nucleotide catabolic process GO:0009166 24 24 0,000 0,14894166 0,17264119 ! ovulation cycle GO:0042698 24 24 0,000 0,14894166 0,17253267 ! maintenance of protein location GO:0045185 25 24 0,000 0,14894166 0,1724243 ! oxidoreduction coenzyme metabolic process GO:0006733 24 24 0,000 0,14894166 0,17231606 ! epithelial tube morphogenesis GO:0060562 25 24 0,000 0,14894166 0,17220796 ! regulation of actin filament polymerization GO:0030833 25 25 0,000 0,1546518 0,17869797 ! protein amino acid N-linked glycosylation GO:0006487 25 25 0,000 0,1546518 0,178586 ! regulation of gene-specific transcription GO:0032583 25 25 0,000 0,1546518 0,17847418 ! sensory perception of chemical stimulus GO:0007606 25 25 0,000 0,1546518 0,17836249 ! cellular component disassembly GO:0022411 26 25 0,000 0,1546518 0,17825095 ! endosome transport GO:0016197 25 25 0,000 0,1546518 0,17813954 ! alcohol biosynthetic process GO:0046165 25 25 0,000 0,1546518 0,17802827 ! development of primary female sexual characteristics GO:0046545 25 25 0,000 0,1546518 0,17791714 GO:0046660|female sex differentiation, ! polysaccharide biosynthetic process GO:0000271 25 25 0,000 0,1546518 0,17780615 ! excretion GO:0007588 25 25 0,000 0,1546518 0,1776953 ! gastrulation GO:0007369 25 25 0,000 0,1546518 0,17758459 ! heart morphogenesis GO:0003007 25 25 0,000 0,1546518 0,17747401 ! icosanoid metabolic process GO:0006690 25 25 0,000 0,1546518 0,17736357 ! regulation of endocytosis GO:0030100 25 25 0,000 0,1546518 0,17725327 ! JAK-STAT cascade GO:0007259 26 25 0,000 0,1546518 0,17714311 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 26 26 0,000 0,16032445 0,18352668 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 26 26 0,000 0,16032445 0,18341276 ! induction of apoptosis by intracellular signals GO:0008629 26 26 0,000 0,16032445 0,18329898 ! cellular defense response GO:0006968 26 26 0,000 0,16032445 0,18318534 ! positive regulation of cytokine biosynthetic process GO:0042108 26 26 0,000 0,16032445 0,18307184 ! germ cell development GO:0007281 27 26 0,000 0,16032445 0,18295849 ! regulation of blood vessel size GO:0050880 27 26 0,000 0,16032445 0,18284527 GO:0035150|regulation of tube size, ! pigment metabolic process GO:0042440 26 26 0,000 0,16032445 0,18273219 ! maintenance of location in cell GO:0051651 27 26 0,000 0,16032445 0,18261926 ! chloride transport GO:0006821 27 27 0,000 0,16595985 0,18892156 ! regulation of neurotransmitter levels GO:0001505 31 27 0,000 0,16595985 0,18880495 ! learning or memory GO:0007611 28 27 0,000 0,16595985 0,18868847 ! monocarboxylic acid transport GO:0015718 27 27 0,000 0,16595985 0,18857214 ! cAMP-mediated signaling GO:0019933 27 27 0,000 0,16595985 0,18845595 ! peptide metabolic process GO:0006518 29 27 0,000 0,16595985 0,18833991 ! activation of caspase activity GO:0006919 27 27 0,000 0,16595985 0,18822401 ! inner ear development GO:0048839 27 27 0,000 0,16595985 0,18810825 ! isoprenoid metabolic process GO:0006720 27 27 0,000 0,16595985 0,18799263 ! glutamine family amino acid metabolic process GO:0009064 28 27 0,000 0,16595985 0,18787716 ! cell growth GO:0016049 27 27 0,000 0,16595985 0,18776182 ! tRNA aminoacylation for protein translation GO:0006418 28 28 0,000 0,17155826 0,1939766 GO:0043038|amino acid activation, GO:0043039|tRNA aminoacylation, ! stress-activated protein kinase signaling pathway GO:0031098 28 28 0,000 0,17155826 0,19385767 GO:0007254|JNK cascade, ! neuromuscular process GO:0050905 28 28 0,000 0,17155826 0,19373889 ! regulation of muscle contraction GO:0006937 28 28 0,000 0,17155826 0,19362025 ! unsaturated fatty acid metabolic process GO:0033559 28 28 0,000 0,17155826 0,19350175 ! sulfur compound biosynthetic process GO:0044272 28 28 0,000 0,17155826 0,1933834 ! keratinocyte differentiation GO:0030216 28 28 0,000 0,17155826 0,1932652 ! developmental growth GO:0048589 28 28 0,000 0,17155826 0,19314714 ! glycerophospholipid biosynthetic process GO:0046474 30 29 0,000 0,17711989 0,19928691 ! viral reproductive process GO:0022415 29 29 0,000 0,17711989 0,19916532 ! phosphoinositide metabolic process GO:0030384 29 29 0,000 0,17711989 0,19904388 ! branching morphogenesis of a tube GO:0048754 29 29 0,000 0,17711989 0,19892258 ! antigen processing and presentation GO:0019882 29 29 0,000 0,17711989 0,19880144 ! tRNA processing GO:0008033 29 29 0,000 0,17711989 0,19868044 ! regulation of gene expression, epigenetic GO:0040029 29 29 0,000 0,17711989 0,19855959 ! adult behavior GO:0030534 30 29 0,000 0,17711989 0,19843888 ! regulation of protein polymerization GO:0032271 29 29 0,000 0,17711989 0,19831832 ! transition metal ion transport GO:0000041 31 30 0,000 0,18264499 0,20438052 ! RNA catabolic process GO:0006401 30 30 0,000 0,18264499 0,20425651 ! response to reactive oxygen species GO:0000302 31 30 0,000 0,18264499 0,20413264 ! ER to Golgi vesicle-mediated transport GO:0006888 30 30 0,000 0,18264499 0,20400892 ! positive regulation of peptidase activity GO:0010952 30 30 0,000 0,18264499 0,20388536 GO:0043280|positive regulation of caspase activity, ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 30 30 0,000 0,18264499 0,20376194 ! neuropeptide signaling pathway GO:0007218 30 30 0,000 0,18264499 0,20363867 ! regulation of protein complex disassembly GO:0043244 30 30 0,000 0,18264499 0,20351555 ! response to temperature stimulus GO:0009266 30 30 0,000 0,18264499 0,20339258 ! immunoglobulin mediated immune response GO:0016064 30 30 0,000 0,18264499 0,20326976 GO:0019724|B cell mediated immunity, ! water-soluble vitamin metabolic process GO:0006767 30 30 0,000 0,18264499 0,20314709 ! cellular amino acid derivative biosynthetic process GO:0042398 31 30 0,000 0,18264499 0,20302456 ! regulation of translational initiation GO:0006446 31 31 0,000 0,1881338 0,20899976 ! B cell activation GO:0042113 31 31 0,000 0,1881338 0,20887385 ! negative regulation of cytoskeleton organization GO:0051494 32 31 0,000 0,1881338 0,2087481 ! lipoprotein metabolic process GO:0042157 31 31 0,000 0,1881338 0,2086225 ! ion transmembrane transport GO:0034220 31 31 0,000 0,1881338 0,20849705 GO:0015985|energy coupled proton transport, down electrochemical gradient, GO:0015986|ATP synthesis coupled proton transport, ! aging GO:0007568 32 31 0,000 0,1881338 0,20837175 ! glycerolipid biosynthetic process GO:0045017 32 31 0,000 0,1881338 0,2082466 ! digestion GO:0007586 31 31 0,000 0,1881338 0,20812161 ! nucleoside metabolic process GO:0009116 31 31 0,000 0,1881338 0,20799676 ! regulation of heart contraction GO:0008016 31 31 0,000 0,1881338 0,20787206 ! sphingolipid metabolic process GO:0006665 31 31 0,000 0,1881338 0,20774751 ! camera-type eye development GO:0043010 31 31 0,000 0,1881338 0,20762311 ! extracellular matrix organization GO:0030198 31 31 0,000 0,1881338 0,20749886 ! ribonucleoprotein complex assembly GO:0022618 32 31 0,000 0,1881338 0,20737476 ! epidermal cell differentiation GO:0009913 31 31 0,000 0,1881338 0,2072508 ! cell redox homeostasis GO:0045454 32 32 0,000 0,19358655 0,21313023 ! lipid modification GO:0030258 32 32 0,000 0,19358655 0,21300299 ! glycosaminoglycan metabolic process GO:0030203 34 32 0,000 0,19358655 0,2128759 ! regulation of vesicle-mediated transport GO:0060627 33 32 0,000 0,19358655 0,21274896 ! cell maturation GO:0048469 32 32 0,000 0,19358655 0,21262217 ! morphogenesis of a branching structure GO:0001763 32 32 0,000 0,19358655 0,21249554 ! nuclear export GO:0051168 32 32 0,000 0,19358655 0,21236905 ! kidney development GO:0001822 32 32 0,000 0,19358655 0,21224271 ! maintenance of location GO:0051235 33 32 0,000 0,19358655 0,21211653 ! regulation of cellular response to stress GO:0080135 35 33 0,000 0,19900346 0,21792238 ! membrane lipid metabolic process GO:0006643 33 33 0,000 0,19900346 0,21779298 ! regulation of actin polymerization or depolymerization GO:0008064 33 33 0,000 0,19900346 0,21766372 ! regulation of neuron differentiation GO:0045664 34 33 0,000 0,19900346 0,21753462 ! regulation of neuron apoptosis GO:0043523 34 33 0,000 0,19900346 0,21740567 ! regulation of synaptic transmission GO:0050804 33 33 0,000 0,19900346 0,21727688 ! regulation of actin filament length GO:0030832 34 34 0,000 0,20438477 0,22302021 ! response to metal ion GO:0010038 34 34 0,000 0,20438477 0,22288824 ! ear development GO:0043583 34 34 0,000 0,20438477 0,22275643 ! coenzyme biosynthetic process GO:0009108 34 34 0,000 0,20438477 0,22262478 ! nucleoside monophosphate biosynthetic process GO:0009124 34 34 0,000 0,20438477 0,22249328 ! secondary metabolic process GO:0019748 34 34 0,000 0,20438477 0,22236194 ! negative regulation of response to stimulus GO:0048585 34 34 0,000 0,20438477 0,22223076 ! viral reproduction GO:0016032 34 34 0,000 0,20438477 0,22209972 ! detection of stimulus GO:0051606 36 34 0,000 0,20438477 0,22196885 ! regulation of cellular component size GO:0032535 35 35 0,000 0,20973071 0,22764058 ! inorganic anion transport GO:0015698 35 35 0,000 0,20973071 0,22750659 ! hydrogen transport GO:0006818 36 36 0,000 0,2150415 0,23313029 GO:0015992|proton transport, ! response to inorganic substance GO:0010035 36 36 0,000 0,2150415 0,23299323 ! aminoglycan metabolic process GO:0006022 38 36 0,000 0,2150415 0,23285634 ! oxygen and reactive oxygen species metabolic process GO:0006800 37 36 0,000 0,2150415 0,23271961 ! embryonic limb morphogenesis GO:0030326 36 36 0,000 0,2150415 0,23258303 GO:0035113|embryonic appendage morphogenesis, ! RNA elongation from RNA polymerase II promoter GO:0006368 36 36 0,000 0,2150415 0,23244662 ! heterocycle catabolic process GO:0046700 36 36 0,000 0,2150415 0,23231037 ! regulation of transmission of nerve impulse GO:0051969 36 36 0,000 0,2150415 0,23217428 ! activation of immune response GO:0002253 36 36 0,000 0,2150415 0,23203834 ! regulation of adenylate cyclase activity GO:0045761 37 37 0,000 0,22031738 0,23759212 GO:0031279|regulation of cyclase activity, GO:0051339|regulation of lyase activity, ! response to drug GO:0042493 37 37 0,000 0,22031738 0,23745318 ! lymphocyte mediated immunity GO:0002449 37 37 0,000 0,22031738 0,23731439 ! eye development GO:0001654 37 37 0,000 0,22031738 0,23717578 ! ATP synthesis coupled electron transport GO:0042773 37 37 0,000 0,22031738 0,23703732 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! cellular amino acid catabolic process GO:0009063 38 37 0,000 0,22031738 0,23689903 ! neurotransmitter transport GO:0006836 40 38 0,000 0,22555856 0,24239325 ! cellular hormone metabolic process GO:0034754 39 38 0,000 0,22555856 0,242252 ! RNA elongation GO:0006354 38 38 0,000 0,22555856 0,24211091 ! regulation of neurological system process GO:0031644 38 38 0,000 0,22555856 0,24196998 ! regulation of cAMP biosynthetic process GO:0030817 39 39 0,000 0,23076527 0,24741151 ! activation of MAPK activity GO:0000187 39 39 0,000 0,23076527 0,24726767 ! response to unfolded protein GO:0006986 39 39 0,000 0,23076527 0,24712399 ! nucleoside monophosphate metabolic process GO:0009123 39 39 0,000 0,23076527 0,24698048 ! fatty acid biosynthetic process GO:0006633 39 39 0,000 0,23076527 0,24683714 ! intracellular protein transmembrane transport GO:0065002 39 39 0,000 0,23076527 0,24669396 ! developmental maturation GO:0021700 39 39 0,000 0,23076527 0,24655095 ! lymphocyte differentiation GO:0030098 39 39 0,000 0,23076527 0,24640811 ! limb development GO:0060173 39 39 0,000 0,23076527 0,24626543 GO:0048736|appendage development, GO:0035107|appendage morphogenesis, ! regulation of cAMP metabolic process GO:0030814 40 40 0,000 0,23593773 0,2516396 ! DNA catabolic process GO:0006308 41 40 0,000 0,23593773 0,25149406 ! regulation of nucleotide biosynthetic process GO:0030808 41 41 0,000 0,24107616 0,25682275 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! amine catabolic process GO:0009310 42 41 0,000 0,24107616 0,25667439 ! elevation of cytosolic calcium ion concentration GO:0007204 41 41 0,000 0,24107616 0,25652619 ! regulation of caspase activity GO:0043281 41 41 0,000 0,24107616 0,25637817 ! phospholipid biosynthetic process GO:0008654 42 41 0,000 0,24107616 0,25623031 ! regulation of Ras GTPase activity GO:0032318 41 41 0,000 0,24107616 0,25608263 ! respiratory electron transport chain GO:0022904 43 42 0,000 0,24618078 0,26135436 ! regulation of cyclic nucleotide metabolic process GO:0030799 42 42 0,000 0,24618078 0,2612039 ! regulation of endopeptidase activity GO:0052548 42 42 0,000 0,24618078 0,26105361 ! cytosolic calcium ion homeostasis GO:0051480 42 42 0,000 0,24618078 0,26090349 ! negative regulation of ligase activity GO:0051352 43 42 0,000 0,24618078 0,26075355 GO:0051444|negative regulation of ubiquitin-protein ligase activity, GO:0051436|negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle, ! response to protein stimulus GO:0051789 42 42 0,000 0,24618078 0,26060378 ! forebrain development GO:0030900 43 42 0,000 0,24618078 0,26045418 ! one-carbon metabolic process GO:0006730 42 42 0,000 0,24618078 0,26030475 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 43 43 0,000 0,25125181 0,26551438 ! mitochondrion organization GO:0007005 44 43 0,000 0,25125181 0,26536222 ! regulation of nucleotide metabolic process GO:0006140 43 43 0,000 0,25125181 0,26521024 ! mRNA transport GO:0051028 44 44 0,000 0,25628946 0,27037291 ! vitamin metabolic process GO:0006766 44 44 0,000 0,25628946 0,27021823 ! amine biosynthetic process GO:0009309 46 45 0,000 0,26129395 0,27533719 ! homophilic cell adhesion GO:0007156 45 45 0,000 0,26129395 0,27517985 ! regulation of actin cytoskeleton organization GO:0032956 46 45 0,000 0,26129395 0,2750227 ! regulation of actin filament-based process GO:0032970 47 46 0,000 0,26626549 0,28009549 ! cyclic-nucleotide-mediated signaling GO:0019935 46 46 0,000 0,26626549 0,27993571 ! tube morphogenesis GO:0035239 47 46 0,000 0,26626549 0,27977611 ! regulation of peptidase activity GO:0052547 46 46 0,000 0,26626549 0,27961669 ! transcription initiation from RNA polymerase II promoter GO:0006367 46 46 0,000 0,26626549 0,27945746 ! regulation of blood pressure GO:0008217 48 47 0,000 0,27120429 0,28447895 ! rhythmic process GO:0048511 47 47 0,000 0,27120429 0,28431713 ! calcium ion transport GO:0006816 48 48 0,000 0,27611057 0,28929607 ! glycerophospholipid metabolic process GO:0006650 49 48 0,000 0,27611057 0,28913169 ! cellular lipid catabolic process GO:0044242 50 49 0,000 0,28098453 0,29406842 ! divalent metal ion transport GO:0070838 49 49 0,000 0,28098453 0,29390153 ! cofactor biosynthetic process GO:0051188 49 49 0,000 0,28098453 0,29373482 ! chromatin assembly GO:0031497 50 50 0,000 0,28582639 0,298627 GO:0006334|nucleosome assembly, ! RNA transport GO:0050658 50 50 0,000 0,28582639 0,29845781 GO:0050657|nucleic acid transport, GO:0051236|establishment of RNA localization, ! T cell activation GO:0042110 51 50 0,000 0,28582639 0,29828881 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 50 50 0,000 0,28582639 0,29812 ! nitrogen compound catabolic process GO:0044270 51 50 0,000 0,28582639 0,29795138 ! regulation of neurogenesis GO:0050767 51 50 0,000 0,28582639 0,29778295 ! transcription initiation GO:0006352 50 50 0,000 0,28582639 0,29761471 ! biogenic amine metabolic process GO:0006576 52 51 0,000 0,29063634 0,30245216 ! positive regulation of immune response GO:0050778 51 51 0,000 0,29063634 0,30228148 ! rRNA metabolic process GO:0016072 51 51 0,000 0,29063634 0,30211099 GO:0006364|rRNA processing, ! protein-DNA complex assembly GO:0065004 51 51 0,000 0,29063634 0,30194069 ! ATP biosynthetic process GO:0006754 51 51 0,000 0,29063634 0,30177058 ! RNA localization GO:0006403 52 52 0,000 0,2954146 0,30655918 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 52 52 0,000 0,2954146 0,30638667 ! cell fate commitment GO:0045165 52 52 0,000 0,2954146 0,30621435 ! regulation of GTPase activity GO:0043087 53 52 0,000 0,2954146 0,30604222 ! sodium ion transport GO:0006814 53 53 0,000 0,30016137 0,31078506 ! tRNA metabolic process GO:0006399 53 53 0,000 0,30016137 0,31061056 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 53 53 0,000 0,30016137 0,31043625 ! carbohydrate biosynthetic process GO:0016051 53 53 0,000 0,30016137 0,31026214 ! hormone metabolic process GO:0042445 55 54 0,000 0,30487685 0,31495966 ! sulfur metabolic process GO:0006790 55 54 0,000 0,30487685 0,31478321 ! nucleosome organization GO:0034728 55 55 0,000 0,30956124 0,31944085 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 55 55 0,000 0,30956124 0,3192621 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! ribonucleoside triphosphate biosynthetic process GO:0009201 56 56 0,000 0,31421475 0,32388019 ! regulation of nervous system development GO:0051960 57 56 0,000 0,31421475 0,32369915 ! ATP metabolic process GO:0046034 57 57 0,000 0,31883757 0,32827801 ! nucleoside triphosphate biosynthetic process GO:0009142 57 57 0,000 0,31883757 0,32809471 ! innate immune response GO:0045087 58 58 0,000 0,3234299 0,33263465 ! regulation of cell development GO:0060284 60 59 0,000 0,32799193 0,33713839 ! cellular aromatic compound metabolic process GO:0006725 60 59 0,000 0,32799193 0,33695047 ! potassium ion transport GO:0006813 60 60 0,000 0,33252388 0,34141588 ! negative regulation of cellular protein metabolic process GO:0032269 60 60 0,000 0,33252388 0,34122578 ! carboxylic acid catabolic process GO:0046395 63 61 0,000 0,33702591 0,34565318 GO:0016054|organic acid catabolic process, ! lipid transport GO:0006869 62 62 0,000 0,34149824 0,3500452 ! purine ribonucleoside triphosphate metabolic process GO:0009205 62 62 0,000 0,34149824 0,34985062 ! di-, tri-valent inorganic cation transport GO:0015674 63 62 0,000 0,34149824 0,34965626 ! ribonucleoside triphosphate metabolic process GO:0009199 63 63 0,000 0,34594105 0,35400853 ! purine nucleoside triphosphate metabolic process GO:0009144 63 63 0,000 0,34594105 0,35381208 ! glycerolipid metabolic process GO:0046486 65 64 0,000 0,35035454 0,35812724 ! regulation of cytoskeleton organization GO:0051493 66 64 0,000 0,35035454 0,35792872 ! anion transport GO:0006820 65 65 0,000 0,35473888 0,36220707 ! protein amino acid glycosylation GO:0006486 66 66 0,000 0,35909427 0,36645113 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! nucleoside triphosphate metabolic process GO:0009141 66 66 0,000 0,35909427 0,36624834 ! DNA packaging GO:0006323 66 66 0,000 0,35909427 0,36604577 ! negative regulation of protein metabolic process GO:0051248 66 66 0,000 0,35909427 0,36584342 ! muscle contraction GO:0006936 67 67 0,000 0,36342091 0,37004681 ! negative regulation of cell differentiation GO:0045596 68 67 0,000 0,36342091 0,36984248 ! Ras protein signal transduction GO:0007265 69 67 0,000 0,36342091 0,36963837 ! purine ribonucleotide biosynthetic process GO:0009152 68 68 0,000 0,36771896 0,37380366 ! chromatin assembly or disassembly GO:0006333 68 68 0,000 0,36771896 0,3735976 ! sensory perception of sound GO:0007605 71 69 0,000 0,37198862 0,37772729 GO:0050954|sensory perception of mechanical stimulus, ! growth GO:0040007 70 70 0,000 0,37623007 0,3818238 ! carboxylic acid biosynthetic process GO:0046394 70 70 0,000 0,37623007 0,38161366 GO:0016053|organic acid biosynthetic process, ! translational elongation GO:0006414 71 71 0,000 0,38044349 0,38567512 ! oxidative phosphorylation GO:0006119 71 71 0,000 0,38044349 0,38546309 ! ribosome biogenesis GO:0042254 71 71 0,000 0,38044349 0,3852513 ! negative regulation of signal transduction GO:0009968 71 71 0,000 0,38044349 0,38503974 ! muscle system process GO:0003012 72 72 0,000 0,38462907 0,38906223 ! sensory organ development GO:0007423 72 72 0,000 0,38462907 0,38884881 ! electron transport chain GO:0022900 75 74 0,000 0,39291741 0,3970103 ! ribonucleotide biosynthetic process GO:0009260 75 75 0,000 0,39702052 0,40093634 ! response to oxidative stress GO:0006979 76 75 0,000 0,39702052 0,40071677 ! purine ribonucleotide metabolic process GO:0009150 75 75 0,000 0,39702052 0,40049744 ! negative regulation of cell communication GO:0010648 76 76 0,000 0,4010965 0,40438778 ! glycoprotein biosynthetic process GO:0009101 80 80 0,000 0,41713259 0,42032552 ! MAPKKK cascade GO:0000165 82 81 0,000 0,42107552 0,42406677 ! lymphocyte activation GO:0046649 82 81 0,000 0,42107552 0,42383516 ! lipid catabolic process GO:0016042 82 81 0,000 0,42107552 0,42360381 ! ribonucleotide metabolic process GO:0009259 83 83 0,000 0,42888325 0,43122304 ! ncRNA processing GO:0034470 83 83 0,000 0,42888325 0,43098791 ! cellular amino acid derivative metabolic process GO:0006575 87 84 0,000 0,43274839 0,43463504 ! nitrogen compound biosynthetic process GO:0044271 86 85 0,000 0,43658794 0,43825249 ! organophosphate metabolic process GO:0019637 87 86 0,000 0,44040207 0,4418405 GO:0006644|phospholipid metabolic process, ! male gamete generation GO:0048232 90 88 0,000 0,44795468 0,44917328 GO:0007283|spermatogenesis, ! purine nucleotide biosynthetic process GO:0006164 88 88 0,000 0,44795468 0,44892903 ! visual perception GO:0007601 93 92 0,000 0,46276197 0,46351647 GO:0050953|sensory perception of light stimulus, ! fatty acid metabolic process GO:0006631 93 92 0,000 0,46276197 0,46326469 ! endocytosis GO:0006897 99 98 0,000 0,48424709 0,48450998 GO:0010324|membrane invagination, ! regulation of system process GO:0044057 98 98 0,000 0,48424709 0,48424709