pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6827-Schmidt-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! negative regulation of phosphorylation GO:0042326 41 23 5,000 1,571E-08 3,614E-05 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 5,000 2,722E-08 3,131E-05 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of lipid kinase activity GO:0043550 12 7 3,000 1,101E-07 8,441E-05 ! induction of positive chemotaxis GO:0050930 14 8 3,000 2,189E-07 1,259E-04 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 3,000 2,189E-07 1,007E-04 ! negative regulation of protein kinase activity GO:0006469 99 57 6,000 2,424E-07 9,294E-05 ! negative regulation of kinase activity GO:0033673 100 58 6,000 2,74E-07 9,002E-05 ! positive regulation of locomotion GO:0040017 35 20 4,000 3,343E-07 9,611E-05 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! negative regulation of transferase activity GO:0051348 105 61 6,000 3,901E-07 9,969E-05 ! regulation of chemotaxis GO:0050920 36 21 4,000 4,361E-07 1,003E-04 ! regulation of transcription factor activity GO:0051090 97 63 6,000 4,885E-07 1,021E-04 GO:0090046|regulation of transcription regulator activity, ! regulation of behavior GO:0050795 38 22 4,000 5,609E-07 1,075E-04 ! protein sumoylation GO:0016925 12 10 3,000 6,49E-07 1,148E-04 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 5,000 8,377E-07 1,376E-04 ! regulation of positive chemotaxis GO:0050926 17 11 3,000 1,014E-06 1,554E-04 GO:0050927|positive regulation of positive chemotaxis, ! negative regulation of transcription regulator activity GO:0090048 47 27 4,000 1,668E-06 2,397E-04 GO:0043433|negative regulation of transcription factor activity, ! regulation of DNA binding GO:0051101 119 77 6,000 1,944E-06 2,63E-04 ! positive regulation of protein complex assembly GO:0031334 19 13 3,000 2,171E-06 2,774E-04 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 3,000 2,171E-06 2,628E-04 ! regulation of protein complex assembly GO:0043254 81 54 5,000 3,314E-06 3,811E-04 ! regulation of protein localization GO:0032880 132 85 6,000 3,793E-06 4,155E-04 ! nuclear migration GO:0007097 10 5 2,000 4,257E-06 4,451E-04 ! positive regulation of pseudopodium assembly GO:0031274 13 5 2,000 4,257E-06 4,257E-04 GO:0031272|regulation of pseudopodium assembly, ! negative regulation of DNA binding GO:0043392 54 33 4,000 4,727E-06 4,53E-04 ! establishment or maintenance of cell polarity GO:0007163 61 34 4,000 5,508E-06 5,067E-04 ! negative regulation of binding GO:0051100 58 36 4,000 7,372E-06 6,522E-04 ! regulation of binding GO:0051098 151 95 6,000 7,974E-06 6,793E-04 ! regulation of protein export from nucleus GO:0046825 6 6 2,000 8,467E-06 6,955E-04 ! macrophage differentiation GO:0030225 10 6 2,000 8,467E-06 6,715E-04 ! regulation of cellular component biogenesis GO:0044087 158 96 6,000 8,547E-06 6,553E-04 ! regulation of epithelial cell proliferation GO:0050678 71 39 4,000 1,105E-05 8,202E-04 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 3,000 1,136E-05 8,163E-04 ! positive regulation of response to external stimulus GO:0032103 65 40 4,000 1,256E-05 8,752E-04 ! induction of apoptosis by intracellular signals GO:0008629 67 40 4,000 1,256E-05 8,495E-04 ! positive regulation of inflammatory response GO:0050729 30 20 3,000 1,411E-05 9,274E-04 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 2,000 1,474E-05 9,414E-04 ! establishment of nucleus localization GO:0040023 13 7 2,000 1,474E-05 9,16E-04 ! regulation of mast cell proliferation GO:0070666 64 44 4,000 2,023E-05 1,224E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 2,000 2,344E-05 1,383E-03 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 2,000 2,344E-05 1,348E-03 ! phosphoinositide 3-kinase cascade GO:0014065 23 8 2,000 2,344E-05 1,315E-03 ! regulation of leukocyte proliferation GO:0070663 71 47 4,000 2,805E-05 1,536E-03 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! motor axon guidance GO:0008045 14 9 2,000 3,497E-05 1,871E-03 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 2,000 3,497E-05 1,828E-03 ! nucleus localization GO:0051647 15 9 2,000 3,497E-05 1,787E-03 ! membrane fusion GO:0006944 80 50 4,000 3,805E-05 1,902E-03 ! negative regulation of protein modification process GO:0031400 50 26 3,000 4,203E-05 2,057E-03 ! establishment of organelle localization GO:0051656 85 52 4,000 4,61E-05 2,209E-03 ! cell cycle arrest GO:0007050 150 86 5,000 4,945E-05 2,321E-03 ! interphase of mitotic cell cycle GO:0051329 156 86 5,000 4,945E-05 2,275E-03 ! regulation of B cell proliferation GO:0030888 15 10 2,000 4,968E-05 2,241E-03 ! regulation of cell projection assembly GO:0060491 20 10 2,000 4,968E-05 2,197E-03 ! positive regulation of leukocyte migration GO:0002687 23 10 2,000 4,968E-05 2,156E-03 ! interphase GO:0051325 159 88 5,000 5,629E-05 2,398E-03 ! regulation of B cell activation GO:0050864 42 28 3,000 5,689E-05 2,379E-03 ! protein modification by small protein conjugation GO:0032446 140 90 5,000 6,388E-05 2,624E-03 ! double-strand break repair via homologous recombination GO:0000724 16 11 2,000 6,793E-05 2,741E-03 GO:0000725|recombinational repair, ! filopodium assembly GO:0046847 19 11 2,000 6,793E-05 2,694E-03 ! chondrocyte differentiation GO:0002062 17 11 2,000 6,793E-05 2,648E-03 ! regulation of leukocyte migration GO:0002685 24 11 2,000 6,793E-05 2,604E-03 ! negative regulation of glucose import GO:0046325 14 11 2,000 6,793E-05 2,561E-03 GO:0010829|negative regulation of glucose transport, ! negative regulation of mast cell proliferation GO:0070667 17 11 2,000 6,793E-05 2,52E-03 GO:0042130|negative regulation of T cell proliferation, ! leukocyte chemotaxis GO:0030595 43 31 3,000 8,59E-05 3,136E-03 GO:0060326|cell chemotaxis, ! microspike assembly GO:0030035 23 12 2,000 9,007E-05 3,237E-03 ! protein modification by small protein conjugation or removal GO:0070647 148 96 5,000 9,164E-05 3,243E-03 ! organelle localization GO:0051640 96 62 4,000 1,08E-04 3,764E-03 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 4,000 1,166E-04 4,003E-03 ! regulation of the force of heart contraction GO:0002026 21 15 2,000 1,832E-04 6,196E-03 ! negative regulation of leukocyte proliferation GO:0070664 25 15 2,000 1,832E-04 6,106E-03 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of phosphorylation GO:0042327 102 70 4,000 1,925E-04 6,324E-03 ! regulation of T cell proliferation GO:0042129 58 38 3,000 1,934E-04 6,265E-03 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 4,000 2,198E-04 7,021E-03 GO:0045937|positive regulation of phosphate metabolic process, ! neutrophil chemotaxis GO:0030593 21 16 2,000 2,242E-04 7,064E-03 ! negative regulation of transport GO:0051051 116 73 4,000 2,345E-04 7,29E-03 ! regulation of T cell differentiation GO:0045580 59 41 3,000 2,607E-04 7,994E-03 ! inactivation of MAPK activity GO:0000188 27 17 2,000 2,708E-04 8,194E-03 ! leukocyte migration GO:0050900 60 43 3,000 3,14E-04 9,378E-03 ! pancreas development GO:0031016 26 18 2,000 3,231E-04 9,527E-03 ! regulation of glucose import GO:0046324 21 18 2,000 3,231E-04 9,407E-03 GO:0010827|regulation of glucose transport, ! negative regulation of T cell activation GO:0050868 25 18 2,000 3,231E-04 9,289E-03 ! regulation of action potential GO:0001508 71 44 3,000 3,433E-04 9,749E-03 ! regulation of inflammatory response GO:0050727 60 44 3,000 3,433E-04 9,63E-03 ! positive regulation of cell cycle GO:0045787 77 45 3,000 3,746E-04 0,01038079 ! positive regulation of defense response GO:0031349 59 45 3,000 3,746E-04 0,01025721 ! protein amino acid autophosphorylation GO:0046777 80 45 3,000 3,746E-04 0,01013654 ! plasma membrane fusion GO:0045026 23 19 2,000 3,815E-04 0,01020419 ! response to UV GO:0009411 75 46 3,000 4,079E-04 0,01078321 ! positive regulation of osteoblast differentiation GO:0045669 33 20 2,000 4,464E-04 0,011667 ! positive regulation of B cell activation GO:0050871 31 20 2,000 4,464E-04 0,01153591 ! regulation of DNA metabolic process GO:0051052 135 85 4,000 4,763E-04 0,01217101 ! regulation of muscle contraction GO:0006937 69 48 3,000 4,807E-04 0,01214914 ! regulation of lymphocyte differentiation GO:0045619 69 48 3,000 4,807E-04 0,01201708 ! myeloid leukocyte differentiation GO:0002573 33 21 2,000 5,179E-04 0,01280826 ! platelet activation GO:0030168 28 21 2,000 5,179E-04 0,012672 ! regulation of angiogenesis GO:0045765 94 49 3,000 5,203E-04 0,01259791 ! cartilage development GO:0051216 70 49 3,000 5,203E-04 0,01246668 ! negative regulation of bone resorption GO:0045779 10 5 1,000 5,659E-04 0,01341845 ! regulation of collagen biosynthetic process GO:0032965 6 5 1,000 5,659E-04 0,01328153 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 1,000 5,659E-04 0,01314737 ! response to protozoan GO:0001562 9 5 1,000 5,659E-04 0,0130159 ! neutrophil mediated immunity GO:0002446 6 5 1,000 5,659E-04 0,01288703 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 1,000 5,659E-04 0,01276068 GO:0033135|regulation of peptidyl-serine phosphorylation, ! microvillus organization GO:0032528 7 5 1,000 5,659E-04 0,01263679 GO:0030033|microvillus assembly, ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 1,000 5,659E-04 0,01251529 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 1,000 5,659E-04 0,01239609 ! negative regulation of gliogenesis GO:0014014 16 5 1,000 5,659E-04 0,01227915 GO:0045686|negative regulation of glial cell differentiation, ! centrosome duplication GO:0051298 5 5 1,000 5,659E-04 0,01216439 ! response to UV-C GO:0010225 6 5 1,000 5,659E-04 0,01205176 ! cranial nerve morphogenesis GO:0021602 6 5 1,000 5,659E-04 0,01194119 ! positive regulation of chemokine production GO:0032722 7 5 1,000 5,659E-04 0,01183263 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 1,000 5,659E-04 0,01172603 ! vasculogenesis GO:0001570 33 22 2,000 5,963E-04 0,01224643 ! blastocyst development GO:0001824 37 22 2,000 5,963E-04 0,01213805 ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 3,000 6,066E-04 0,0122379 ! positive regulation of cell migration GO:0030335 92 51 3,000 6,066E-04 0,01213148 ! myelination GO:0042552 35 23 2,000 6,82E-04 0,01352239 ! regulation of bone remodeling GO:0046850 90 53 3,000 7,025E-04 0,0138094 ! cell projection assembly GO:0030031 76 53 3,000 7,025E-04 0,01369238 ! regulation of tissue remodeling GO:0034103 91 54 3,000 7,542E-04 0,0145778 ! positive regulation of cell projection organization GO:0031346 39 24 2,000 7,751E-04 0,01485624 ! insulin receptor signaling pathway GO:0008286 40 24 2,000 7,751E-04 0,01473346 ! regulation of osteoblast differentiation GO:0045667 37 24 2,000 7,751E-04 0,0146127 ! mesoderm development GO:0007498 76 55 3,000 8,086E-04 0,01512103 ! regulation of response to external stimulus GO:0032101 139 96 4,000 8,303E-04 0,01540149 ! cytokinesis during cell cycle GO:0033205 9 6 1,000 8,446E-04 0,01554118 ! male meiosis GO:0007140 7 6 1,000 8,446E-04 0,01541783 ! N-terminal protein amino acid acetylation GO:0006474 7 6 1,000 8,446E-04 0,01529643 ! mRNA stabilization GO:0048255 15 6 1,000 8,446E-04 0,01517693 GO:0043489|RNA stabilization, ! amyloid precursor protein catabolic process GO:0042987 9 6 1,000 8,446E-04 0,01505928 ! drug transport GO:0015893 6 6 1,000 8,446E-04 0,01494344 ! ER overload response GO:0006983 7 6 1,000 8,446E-04 0,01482937 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 1,000 8,446E-04 0,01471702 ! positive regulation of insulin secretion GO:0032024 8 6 1,000 8,446E-04 0,01460637 ! cerebral cortex neuron differentiation GO:0021895 12 6 1,000 8,446E-04 0,01449737 ! regulation of immunoglobulin secretion GO:0051023 6 6 1,000 8,446E-04 0,01438998 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 1,000 8,446E-04 0,01428417 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! regulation of collagen metabolic process GO:0010712 7 6 1,000 8,446E-04 0,01417991 ! enucleate erythrocyte differentiation GO:0043353 9 6 1,000 8,446E-04 0,01407715 ! neutrophil homeostasis GO:0001780 6 6 1,000 8,446E-04 0,01397588 ! salivary gland morphogenesis GO:0007435 11 6 1,000 8,446E-04 0,01387605 ! blastocyst growth GO:0001832 15 6 1,000 8,446E-04 0,01377764 ! organ or tissue specific immune response GO:0002251 7 6 1,000 8,446E-04 0,01368061 ! negative regulation of B cell activation GO:0050869 9 6 1,000 8,446E-04 0,01358494 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 1,000 8,446E-04 0,01349061 ! regulation of lipid metabolic process GO:0019216 84 56 3,000 8,658E-04 0,01373279 ! positive regulation of cell motion GO:0051272 99 56 3,000 8,658E-04 0,01363873 ! peptide transport GO:0015833 43 25 2,000 8,759E-04 0,01370496 ! negative regulation of lymphocyte activation GO:0051250 37 25 2,000 8,759E-04 0,01361236 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 2,000 9,847E-04 0,01519998 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 2,000 9,847E-04 0,01509865 ! myeloid cell differentiation GO:0030099 85 59 3,000 1,054E-03 0,0160562 ! negative regulation of leukocyte activation GO:0002695 39 27 2,000 1,102E-03 0,0166697 ! regulation of heart contraction GO:0008016 91 60 3,000 1,123E-03 0,0168791 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 1,000 1,177E-03 0,0175724 ! oligopeptide transport GO:0006857 11 7 1,000 1,177E-03 0,01745903 ! T-helper 1 type immune response GO:0042088 11 7 1,000 1,177E-03 0,01734711 ! vesicle fusion GO:0006906 15 7 1,000 1,177E-03 0,01723662 ! positive regulation of mitotic cell cycle GO:0045931 11 7 1,000 1,177E-03 0,01712753 ! neuroblast proliferation GO:0007405 13 7 1,000 1,177E-03 0,01701981 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 1,000 1,177E-03 0,01691344 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 1,000 1,177E-03 0,01680838 ! regulation of synaptogenesis GO:0051963 10 7 1,000 1,177E-03 0,01670463 ! trophectodermal cell differentiation GO:0001829 8 7 1,000 1,177E-03 0,01660215 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 1,000 1,177E-03 0,01650091 ! defense response to Gram-negative bacterium GO:0050829 9 7 1,000 1,177E-03 0,01640091 ! meiosis GO:0007126 96 61 3,000 1,195E-03 0,01655183 GO:0051327|M phase of meiotic cell cycle, ! negative regulation of protein complex assembly GO:0031333 42 28 2,000 1,227E-03 0,01689908 ! cell junction assembly GO:0034329 56 28 2,000 1,227E-03 0,01679849 ! negative regulation of MAP kinase activity GO:0043407 54 28 2,000 1,227E-03 0,01669909 ! ensheathment of neurons GO:0007272 43 28 2,000 1,227E-03 0,01660086 GO:0008366|axon ensheathment, ! negative regulation of cell growth GO:0030308 106 62 3,000 1,27E-03 0,01707579 ! meiotic cell cycle GO:0051321 97 62 3,000 1,27E-03 0,01697651 ! cell cycle checkpoint GO:0000075 108 64 3,000 1,429E-03 0,01900062 ! negative regulation of cell size GO:0045792 108 64 3,000 1,429E-03 0,01889142 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 3,000 1,429E-03 0,01878347 ! negative regulation of cell activation GO:0050866 44 30 2,000 1,504E-03 0,01965314 ! positive regulation of B cell proliferation GO:0030890 11 8 1,000 1,561E-03 0,02028376 ! Golgi to endosome transport GO:0006895 16 8 1,000 1,561E-03 0,0201698 ! amyloid precursor protein metabolic process GO:0042982 12 8 1,000 1,561E-03 0,02005712 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 1,000 1,561E-03 0,0199457 ! positive regulation of endothelial cell migration GO:0010595 18 8 1,000 1,561E-03 0,0198355 ! multicellular organism growth GO:0035264 14 8 1,000 1,561E-03 0,01972651 ! retrograde transport, endosome to Golgi GO:0042147 12 8 1,000 1,561E-03 0,01961872 ! regulation of vascular permeability GO:0043114 12 8 1,000 1,561E-03 0,01951209 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 1,000 1,561E-03 0,01940662 ! osteoblast development GO:0002076 13 8 1,000 1,561E-03 0,01930229 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 1,000 1,561E-03 0,01919907 GO:0007351|tripartite regional subdivision, ! regulation of gliogenesis GO:0014013 20 8 1,000 1,561E-03 0,01909694 GO:0045685|regulation of glial cell differentiation, ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 1,000 1,561E-03 0,0189959 ! regulation of macrophage differentiation GO:0045649 14 8 1,000 1,561E-03 0,01889592 ! myeloid cell homeostasis GO:0002262 8 8 1,000 1,561E-03 0,01879699 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 1,000 1,561E-03 0,01869909 ! axon guidance GO:0007411 99 66 3,000 1,602E-03 0,01909477 ! mammary gland development GO:0030879 57 31 2,000 1,656E-03 0,01963086 ! segmentation GO:0035282 41 31 2,000 1,656E-03 0,01953019 ! meiosis I GO:0007127 52 32 2,000 1,817E-03 0,02132213 ! regulation of synaptic plasticity GO:0048167 52 32 2,000 1,817E-03 0,02121389 ! cell junction organization GO:0034330 63 33 2,000 1,988E-03 0,02308918 ! androgen receptor signaling pathway GO:0030521 54 33 2,000 1,988E-03 0,02297315 ! cytokinesis GO:0000910 52 33 2,000 1,988E-03 0,02285829 ! regulation of developmental growth GO:0048638 13 9 1,000 1,997E-03 0,02285086 ! lung alveolus development GO:0048286 17 9 1,000 1,997E-03 0,02273774 ! myeloid leukocyte mediated immunity GO:0002444 11 9 1,000 1,997E-03 0,02262573 ! positive regulation of peptide secretion GO:0002793 15 9 1,000 1,997E-03 0,02251482 ! blastoderm segmentation GO:0007350 11 9 1,000 1,997E-03 0,02240499 ! regulation of hormone metabolic process GO:0032350 15 9 1,000 1,997E-03 0,02229623 ! oocyte differentiation GO:0009994 12 9 1,000 1,997E-03 0,02218851 GO:0048599|oocyte development, ! anterior/posterior axis specification GO:0009948 11 9 1,000 1,997E-03 0,02208184 ! blastocyst formation GO:0001825 12 9 1,000 1,997E-03 0,02197618 ! defense response to Gram-positive bacterium GO:0050830 10 9 1,000 1,997E-03 0,02187154 ! embryonic placenta development GO:0001892 12 9 1,000 1,997E-03 0,02176788 ! sequestering of metal ion GO:0051238 11 9 1,000 1,997E-03 0,0216652 ! regulation of synapse organization GO:0050807 12 9 1,000 1,997E-03 0,02156349 ! localization within membrane GO:0051668 15 9 1,000 1,997E-03 0,02146272 ! phosphoinositide-mediated signaling GO:0048015 109 71 3,000 2,098E-03 0,02244322 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 3,000 2,098E-03 0,02233931 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 2,000 2,168E-03 0,02297875 ! cellular response to insulin stimulus GO:0032869 52 34 2,000 2,168E-03 0,02287334 ! regulation of intracellular protein transport GO:0033157 59 35 2,000 2,358E-03 0,02476602 ! regulation of action potential in neuron GO:0019228 54 35 2,000 2,358E-03 0,02465344 ! positive regulation of leukocyte proliferation GO:0070665 50 35 2,000 2,358E-03 0,02454189 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 1,000 2,484E-03 0,02573294 ! hippocampus development GO:0021766 19 10 1,000 2,484E-03 0,02561754 ! blood vessel remodeling GO:0001974 21 10 1,000 2,484E-03 0,02550318 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 1,000 2,484E-03 0,02538983 GO:0010812|negative regulation of cell-substrate adhesion, ! regulation of chemokine biosynthetic process GO:0045073 12 10 1,000 2,484E-03 0,02527748 ! peptide or protein amino-terminal blocking GO:0018409 14 10 1,000 2,484E-03 0,02516613 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 1,000 2,484E-03 0,02505575 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 1,000 2,484E-03 0,02494634 ! response to X-ray GO:0010165 16 10 1,000 2,484E-03 0,02483788 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 1,000 2,484E-03 0,02473035 ! regulation of bone resorption GO:0045124 24 10 1,000 2,484E-03 0,02462376 ! embryonic axis specification GO:0000578 12 10 1,000 2,484E-03 0,02451808 ! positive regulation of interleukin-6 production GO:0032755 13 10 1,000 2,484E-03 0,0244133 ! cranial nerve development GO:0021545 12 10 1,000 2,484E-03 0,02430941 ! salivary gland development GO:0007431 22 10 1,000 2,484E-03 0,02420641 ! positive regulation of acute inflammatory response GO:0002675 14 10 1,000 2,484E-03 0,02410427 ! regulation of synapse structure and activity GO:0050803 13 10 1,000 2,484E-03 0,02400299 ! positive regulation of transcription factor activity GO:0051091 49 36 2,000 2,558E-03 0,02461999 GO:0090047|positive regulation of transcription regulator activity, ! regulation of hormone secretion GO:0046883 48 36 2,000 2,558E-03 0,02451741 ! negative regulation of growth GO:0045926 123 75 3,000 2,564E-03 0,02446826 ! regulation of ligase activity GO:0051340 114 75 3,000 2,564E-03 0,02436715 ! regulation of protein transport GO:0051223 114 76 3,000 2,691E-03 0,02546608 GO:0070201|regulation of establishment of protein localization, ! gland development GO:0048732 148 77 3,000 2,821E-03 0,02659586 ! positive regulation of protein modification process GO:0031401 107 78 3,000 2,957E-03 0,02775678 ! ER-associated protein catabolic process GO:0030433 14 11 1,000 3,021E-03 0,0282418 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of nitric-oxide synthase activity GO:0050999 20 11 1,000 3,021E-03 0,02812746 ! positive regulation of endothelial cell proliferation GO:0001938 18 11 1,000 3,021E-03 0,02801404 ! regulation of mRNA processing GO:0050684 18 11 1,000 3,021E-03 0,02790154 ! focal adhesion formation GO:0048041 24 11 1,000 3,021E-03 0,02778993 ! membrane protein proteolysis GO:0033619 18 11 1,000 3,021E-03 0,02767921 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of vascular endothelial growth factor production GO:0010574 19 11 1,000 3,021E-03 0,02756938 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 1,000 3,021E-03 0,02746041 ! regulation of cell cycle process GO:0010564 122 81 3,000 3,389E-03 0,03068642 ! double-strand break repair GO:0006302 67 40 2,000 3,463E-03 0,03123205 ! positive regulation of protein transport GO:0051222 55 40 2,000 3,463E-03 0,03111005 ! ossification GO:0001503 134 82 3,000 3,542E-03 0,03169836 GO:0060348|bone development, ! cartilage condensation GO:0001502 18 12 1,000 3,607E-03 0,03215328 ! regulation of skeletal muscle fiber development GO:0048742 20 12 1,000 3,607E-03 0,03202914 ! glycoprotein catabolic process GO:0006516 19 12 1,000 3,607E-03 0,03190595 ! cell-cell junction assembly GO:0007043 18 12 1,000 3,607E-03 0,0317837 ! histone acetylation GO:0016573 23 12 1,000 3,607E-03 0,03166239 ! autonomic nervous system development GO:0048483 23 12 1,000 3,607E-03 0,031542 ! gland morphogenesis GO:0022612 23 12 1,000 3,607E-03 0,03142252 ! peptidyl-lysine modification GO:0018205 18 12 1,000 3,607E-03 0,03130395 ! response to gamma radiation GO:0010332 20 12 1,000 3,607E-03 0,03118626 ! regulation of mRNA stability GO:0043488 27 12 1,000 3,607E-03 0,03106946 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 1,000 3,607E-03 0,03095353 ! endosome transport GO:0016197 71 41 2,000 3,715E-03 0,03176799 ! positive regulation of DNA binding GO:0043388 57 41 2,000 3,715E-03 0,03165033 ! regulation of defense response GO:0031347 117 84 3,000 3,862E-03 0,03277811 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 2,000 3,979E-03 0,03364804 ! Golgi vesicle transport GO:0048193 138 85 3,000 4,029E-03 0,03394665 ! anterior/posterior pattern formation GO:0009952 124 85 3,000 4,029E-03 0,03382276 ! regulation of membrane potential GO:0042391 128 85 3,000 4,029E-03 0,03369977 ! N-terminal protein amino acid modification GO:0031365 18 13 1,000 4,241E-03 0,03534469 ! regulation of chemokine production GO:0032642 17 13 1,000 4,241E-03 0,03521709 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 1,000 4,241E-03 0,03509041 ! organelle fusion GO:0048284 28 13 1,000 4,241E-03 0,03496464 ! endocrine pancreas development GO:0031018 19 13 1,000 4,241E-03 0,03483976 ! exocrine system development GO:0035272 27 13 1,000 4,241E-03 0,03471578 ! regulation of monooxygenase activity GO:0032768 26 13 1,000 4,241E-03 0,03459267 ! regulation of acute inflammatory response GO:0002673 19 13 1,000 4,241E-03 0,03447044 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 1,000 4,241E-03 0,03434906 ! regulation of RNA stability GO:0043487 28 13 1,000 4,241E-03 0,03422854 ! positive regulation of binding GO:0051099 59 43 2,000 4,254E-03 0,03421165 ! DNA-dependent DNA replication GO:0006261 59 43 2,000 4,254E-03 0,03409244 ! response to insulin stimulus GO:0032868 63 43 2,000 4,254E-03 0,03397407 ! skeletal muscle tissue development GO:0007519 123 87 3,000 4,378E-03 0,03484449 GO:0060538|skeletal muscle organ development, ! Wnt receptor signaling pathway GO:0016055 130 87 3,000 4,378E-03 0,03472434 ! regulation of cell projection organization GO:0031344 83 44 2,000 4,54E-03 0,03588555 ! induction of apoptosis by extracellular signals GO:0008624 74 44 2,000 4,54E-03 0,03576265 ! regulation of T cell activation GO:0050863 128 89 3,000 4,747E-03 0,03726386 ! regulation of skeletal muscle tissue development GO:0048641 22 14 1,000 4,924E-03 0,03851869 ! regulation of S phase GO:0033261 18 14 1,000 4,924E-03 0,03838812 ! phosphoinositide phosphorylation GO:0046854 21 14 1,000 4,924E-03 0,03825843 ! negative regulation of bone remodeling GO:0046851 26 14 1,000 4,924E-03 0,03812962 ! limbic system development GO:0021761 25 14 1,000 4,924E-03 0,03800167 ! DNA unwinding during replication GO:0006268 21 14 1,000 4,924E-03 0,03787457 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 1,000 4,924E-03 0,03774832 ! regulation of T-helper 2 type immune response GO:0002828 21 14 1,000 4,924E-03 0,03762291 ! regulation of ATPase activity GO:0043462 18 14 1,000 4,924E-03 0,03749833 ! epithelial to mesenchymal transition GO:0001837 22 14 1,000 4,924E-03 0,03737458 ! peptide hormone secretion GO:0030072 23 14 1,000 4,924E-03 0,03725163 ! regulation of ossification GO:0030278 71 46 2,000 5,147E-03 0,03881283 ! negative regulation of immune system process GO:0002683 73 47 2,000 5,468E-03 0,04109653 ! negative regulation of hormone secretion GO:0046888 20 15 1,000 5,653E-03 0,04235148 ! negative regulation of cell cycle process GO:0010948 24 15 1,000 5,653E-03 0,04221397 ! lipid phosphorylation GO:0046834 23 15 1,000 5,653E-03 0,04207736 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 1,000 5,653E-03 0,04194163 ! myoblast differentiation GO:0045445 27 15 1,000 5,653E-03 0,04180677 ! centrosome cycle GO:0007098 16 15 1,000 5,653E-03 0,04167277 ! peptidyl-serine phosphorylation GO:0018105 23 15 1,000 5,653E-03 0,04153963 ! peptide secretion GO:0002790 27 15 1,000 5,653E-03 0,04140734 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 1,000 5,653E-03 0,04127589 ! negative regulation of tissue remodeling GO:0034104 27 15 1,000 5,653E-03 0,04114527 ! regulation of T-helper cell differentiation GO:0045622 23 15 1,000 5,653E-03 0,04101547 ! defense response to virus GO:0051607 27 15 1,000 5,653E-03 0,04088649 ! regulation of DNA replication GO:0006275 75 48 2,000 5,8E-03 0,04181881 ! angiogenesis GO:0001525 149 95 3,000 5,978E-03 0,04296342 ! regulation of intracellular transport GO:0032386 78 49 2,000 6,144E-03 0,04402543 ! response to light stimulus GO:0009416 153 96 3,000 6,201E-03 0,04429507 ! hormone secretion GO:0046879 25 16 1,000 6,429E-03 0,045776 ! protein amino acid acetylation GO:0006473 28 16 1,000 6,429E-03 0,04563472 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 1,000 6,429E-03 0,0454943 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 1,000 6,429E-03 0,04535475 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 1,000 6,429E-03 0,04521605 ! oogenesis GO:0048477 23 16 1,000 6,429E-03 0,04507819 ! G1 phase GO:0051318 27 16 1,000 6,429E-03 0,04494118 ! nerve development GO:0021675 18 16 1,000 6,429E-03 0,04480499 ! skeletal muscle fiber development GO:0048741 73 50 2,000 6,501E-03 0,0451712 ! positive regulation of secretion GO:0051047 71 51 2,000 6,869E-03 0,0475872 ! activation of phospholipase C activity GO:0007202 87 51 2,000 6,869E-03 0,0474443 GO:0010863|positive regulation of phospholipase C activity, ! muscle fiber development GO:0048747 74 51 2,000 6,869E-03 0,04730225 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 3,000 6,906E-03 0,04741391 ! positive regulation of hormone secretion GO:0046887 24 17 1,000 7,25E-03 0,04962511 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 1,000 7,25E-03 0,04947786 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 1,000 7,25E-03 0,04933147 ! regulation of striated muscle contraction GO:0006942 20 17 1,000 7,25E-03 0,04918595 ! DNA duplex unwinding GO:0032508 25 17 1,000 7,25E-03 0,04904129 GO:0032392|DNA geometric change, ! cell-substrate junction assembly GO:0007044 39 17 1,000 7,25E-03 0,04889747 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 1,000 7,25E-03 0,04875449 ! actin filament bundle formation GO:0051017 26 17 1,000 7,25E-03 0,04861235 ! neuromuscular junction development GO:0007528 23 17 1,000 7,25E-03 0,04847104 ! stem cell differentiation GO:0048863 36 17 1,000 7,25E-03 0,04833054 ! negative regulation of intracellular transport GO:0032387 29 17 1,000 7,25E-03 0,04819086 ! peptidyl-serine modification GO:0018209 27 17 1,000 7,25E-03 0,04805198 ! cell-cell junction organization GO:0045216 25 17 1,000 7,25E-03 0,0479139 ! regulation of immunoglobulin production GO:0002637 25 17 1,000 7,25E-03 0,04777661 ! negative regulation of homeostatic process GO:0032845 28 17 1,000 7,25E-03 0,04764011 ! positive regulation of synaptic transmission GO:0050806 24 17 1,000 7,25E-03 0,04750438 ! positive regulation of phospholipase activity GO:0010518 88 52 2,000 7,25E-03 0,04737 ! aging GO:0007568 79 52 2,000 7,25E-03 0,04723581 ! nucleotide-excision repair GO:0006289 64 52 2,000 7,25E-03 0,04710238 ! skeletal system morphogenesis GO:0048705 78 53 2,000 7,643E-03 0,0495148 ! regulation of phospholipase activity GO:0010517 90 54 2,000 8,048E-03 0,05199352 ! positive regulation of lipase activity GO:0060193 90 54 2,000 8,048E-03 0,05184788 ! positive regulation of translation GO:0045727 28 18 1,000 8,115E-03 0,05213799 ! positive regulation of anti-apoptosis GO:0045768 29 18 1,000 8,115E-03 0,05199276 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 1,000 8,115E-03 0,05184834 ! axis specification GO:0009798 26 18 1,000 8,115E-03 0,05170471 ! apoptotic mitochondrial changes GO:0008637 29 18 1,000 8,115E-03 0,05156188 ! response to retinoic acid GO:0032526 25 18 1,000 8,115E-03 0,05141984 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 1,000 8,115E-03 0,05127858 ! somitogenesis GO:0001756 24 18 1,000 8,115E-03 0,05113809 ! hormone transport GO:0009914 27 18 1,000 8,115E-03 0,05099836 ! negative regulation of neuron differentiation GO:0045665 24 18 1,000 8,115E-03 0,0508594 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 1,000 8,115E-03 0,0507212 ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 1,000 8,115E-03 0,05058374 ! DNA damage response, signal transduction GO:0042770 96 56 2,000 8,895E-03 0,05529632 ! negative regulation of response to stimulus GO:0048585 80 56 2,000 8,895E-03 0,05514727 ! positive regulation of protein catabolic process GO:0045732 23 19 1,000 9,025E-03 0,05580131 ! positive regulation of fibroblast proliferation GO:0048146 27 19 1,000 9,025E-03 0,05565171 ! reciprocal meiotic recombination GO:0007131 31 19 1,000 9,025E-03 0,05550291 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 1,000 9,025E-03 0,0553549 ! calcium-independent cell-cell adhesion GO:0016338 21 19 1,000 9,025E-03 0,05520768 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 1,000 9,025E-03 0,05506124 ! response to vitamin A GO:0033189 26 19 1,000 9,025E-03 0,05491558 ! cell structure disassembly during apoptosis GO:0006921 24 19 1,000 9,025E-03 0,05477068 ! apoptotic nuclear changes GO:0030262 24 19 1,000 9,025E-03 0,05462655 ! sex determination GO:0007530 29 19 1,000 9,025E-03 0,05448317 ! regulation of endothelial cell migration GO:0010594 40 19 1,000 9,025E-03 0,05434055 ! regulation of interleukin-6 production GO:0032675 22 19 1,000 9,025E-03 0,05419867 ! negative regulation of angiogenesis GO:0016525 36 19 1,000 9,025E-03 0,05405752 ! positive regulation of intracellular transport GO:0032388 29 19 1,000 9,025E-03 0,05391711 ! positive regulation of neurological system process GO:0031646 28 19 1,000 9,025E-03 0,05377743 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 1,000 9,025E-03 0,05363847 ! chromosome segregation GO:0007059 83 57 2,000 9,338E-03 0,05535568 ! response to peptide hormone stimulus GO:0043434 84 57 2,000 9,338E-03 0,05521338 ! gonad development GO:0008406 79 57 2,000 9,338E-03 0,05507181 ! steroid hormone receptor signaling pathway GO:0030518 96 58 2,000 9,794E-03 0,05761005 ! response to vitamin GO:0033273 29 20 1,000 9,978E-03 0,05854711 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 1,000 9,978E-03 0,05839813 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 1,000 9,978E-03 0,05824991 ! pallium development GO:0021543 38 20 1,000 9,978E-03 0,05810244 ! lung development GO:0030324 94 59 2,000 0,0102619 0,05960195 ! G2/M transition of mitotic cell cycle GO:0000086 33 21 1,000 0,01097431 0,06357914 ! DNA catabolic process, endonucleolytic GO:0000737 26 21 1,000 0,01097431 0,06341939 ! protein amino acid acylation GO:0043543 37 21 1,000 0,01097431 0,06326045 ! regulation of DNA recombination GO:0000018 40 21 1,000 0,01097431 0,0631023 ! cell aging GO:0007569 32 21 1,000 0,01097431 0,06294493 ! response to endoplasmic reticulum stress GO:0034976 25 21 1,000 0,01097431 0,06278835 ! regulation of insulin secretion GO:0050796 26 21 1,000 0,01097431 0,06263255 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 1,000 0,01097431 0,06247752 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 1,000 0,01097431 0,06232325 ! cholesterol biosynthetic process GO:0006695 29 21 1,000 0,01097431 0,06216975 ! positive regulation of protein secretion GO:0050714 26 21 1,000 0,01097431 0,062017 ! cellular response to extracellular stimulus GO:0031668 32 21 1,000 0,01097431 0,061865 ! response to glucocorticoid stimulus GO:0051384 33 21 1,000 0,01097431 0,06171374 ! acetyl-CoA catabolic process GO:0046356 31 21 1,000 0,01097431 0,06156321 GO:0006099|tricarboxylic acid cycle, ! cell-matrix adhesion GO:0007160 114 61 2,000 0,01123678 0,06288223 ! homeostasis of number of cells GO:0048872 84 61 2,000 0,01123678 0,06272961 ! negative regulation of ligase activity GO:0051352 91 61 2,000 0,01123678 0,06257772 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 2,000 0,01123678 0,06242656 ! respiratory tube development GO:0030323 99 62 2,000 0,01174359 0,06508496 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 2,000 0,01174359 0,0649285 ! regulation of fibroblast proliferation GO:0048145 35 22 1,000 0,01201211 0,06625384 ! regulation of anti-apoptosis GO:0045767 36 22 1,000 0,01201211 0,06609533 ! glutamate signaling pathway GO:0007215 34 22 1,000 0,01201211 0,06593759 ! microtubule organizing center organization GO:0031023 28 22 1,000 0,01201211 0,0657806 GO:0051297|centrosome organization, ! regulation of cell-matrix adhesion GO:0001952 51 22 1,000 0,01201211 0,06562435 GO:0010810|regulation of cell-substrate adhesion, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 1,000 0,01201211 0,06546884 ! coenzyme catabolic process GO:0009109 33 22 1,000 0,01201211 0,06531407 ! leukocyte homeostasis GO:0001776 33 22 1,000 0,01201211 0,06516002 ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 2,000 0,01226338 0,06636655 ! regulation of lipase activity GO:0060191 109 63 2,000 0,01226338 0,06621076 ! respiratory system development GO:0060541 100 64 2,000 0,01279621 0,06892574 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 1,000 0,01309117 0,07034973 ! embryonic pattern specification GO:0009880 31 23 1,000 0,01309117 0,07018574 ! positive regulation of cell adhesion GO:0045785 37 23 1,000 0,01309117 0,07002252 ! acetyl-CoA metabolic process GO:0006084 33 23 1,000 0,01309117 0,06986005 ! cellular iron ion homeostasis GO:0006879 37 23 1,000 0,01309117 0,06969834 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 1,000 0,01309117 0,06953738 ! ER-nuclear signaling pathway GO:0006984 27 23 1,000 0,01309117 0,06937715 ! negative regulation of DNA replication GO:0008156 35 23 1,000 0,01309117 0,06921766 ! vesicle targeting GO:0006903 32 23 1,000 0,01309117 0,06905891 ! response to corticosteroid stimulus GO:0031960 36 23 1,000 0,01309117 0,06890088 ! osteoblast differentiation GO:0001649 40 23 1,000 0,01309117 0,06874357 ! response to molecule of bacterial origin GO:0002237 30 23 1,000 0,01309117 0,06858698 ! reproductive structure development GO:0048608 90 65 2,000 0,01334213 0,06974293 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 2,000 0,01334213 0,06958479 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 2,000 0,01334213 0,06942736 ! cell-substrate adhesion GO:0031589 121 66 2,000 0,01390117 0,0721731 ! regulation of Rho protein signal transduction GO:0035023 111 66 2,000 0,01390117 0,07201054 ! regulation of endothelial cell proliferation GO:0001936 46 24 1,000 0,01421081 0,07344912 ! fat cell differentiation GO:0045444 37 24 1,000 0,01421081 0,07328444 ! negative regulation of cell development GO:0010721 56 24 1,000 0,01421081 0,07312049 GO:0050768|negative regulation of neurogenesis, ! regulation of alpha-beta T cell activation GO:0046634 35 24 1,000 0,01421081 0,07295728 ! base-excision repair GO:0006284 31 24 1,000 0,01421081 0,07279479 ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 1,000 0,01421081 0,07263302 ! regulation of oxidoreductase activity GO:0051341 39 24 1,000 0,01421081 0,07247197 ! development of primary sexual characteristics GO:0045137 92 68 2,000 0,01505878 0,07662654 ! iron ion homeostasis GO:0055072 39 25 1,000 0,01537036 0,07803937 ! regulation of peptide secretion GO:0002791 34 25 1,000 0,01537036 0,07786748 ! regulation of chromosome organization GO:0033044 35 25 1,000 0,01537036 0,07769634 ! positive regulation of MAPKKK cascade GO:0043410 36 25 1,000 0,01537036 0,07752596 ! positive regulation of nuclear division GO:0051785 39 25 1,000 0,01537036 0,07735631 GO:0045840|positive regulation of mitosis, ! activation of protein kinase activity GO:0032147 102 69 2,000 0,01565743 0,07862901 ! response to drug GO:0042493 108 69 2,000 0,01565743 0,0784577 ! positive regulation of ligase activity GO:0051351 99 69 2,000 0,01565743 0,07828714 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 1,000 0,01656917 0,08266614 ! muscle cell differentiation GO:0042692 104 71 2,000 0,01689455 0,08410707 ! response to hypoxia GO:0001666 132 72 2,000 0,01753308 0,08709736 ! regulation of synaptic transmission GO:0050804 109 72 2,000 0,01753308 0,08690965 ! acute-phase response GO:0006953 42 27 1,000 0,01780657 0,08807551 ! response to ionizing radiation GO:0010212 47 27 1,000 0,01780657 0,08788651 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 1,000 0,01780657 0,08769831 ! cofactor catabolic process GO:0051187 45 27 1,000 0,01780657 0,08751092 ! negative regulation of protein transport GO:0051224 49 27 1,000 0,01780657 0,08732433 ! response to steroid hormone stimulus GO:0048545 114 73 2,000 0,01818494 0,08899015 ! response to oxygen levels GO:0070482 137 74 2,000 0,01885017 0,09204965 ! cellular response to hormone stimulus GO:0032870 109 74 2,000 0,01885017 0,09185463 ! positive regulation of lymphocyte activation GO:0051251 108 74 2,000 0,01885017 0,09166043 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 1,000 0,01908192 0,0925916 ! erythrocyte differentiation GO:0030218 38 28 1,000 0,01908192 0,09239667 ! response to organic cyclic substance GO:0014070 47 28 1,000 0,01908192 0,09220256 ! positive regulation of T cell differentiation GO:0045582 39 28 1,000 0,01908192 0,09200926 ! sterol biosynthetic process GO:0016126 40 28 1,000 0,01908192 0,09181677 ! BMP signaling pathway GO:0030509 40 28 1,000 0,01908192 0,09162509 ! positive regulation of catabolic process GO:0009896 40 28 1,000 0,01908192 0,0914342 ! placenta development GO:0001890 37 28 1,000 0,01908192 0,09124411 ! blood coagulation GO:0007596 116 75 2,000 0,01952876 0,09318705 GO:0050817|coagulation, ! response to nutrient GO:0007584 104 75 2,000 0,01952876 0,09299412 ! positive regulation of T cell proliferation GO:0042102 44 29 1,000 0,02039458 0,09691639 ! telencephalon development GO:0021537 52 29 1,000 0,02039458 0,09671656 ! tissue homeostasis GO:0001894 42 29 1,000 0,02039458 0,09651756 GO:0048871|multicellular organismal homeostasis, ! sex differentiation GO:0007548 105 77 2,000 0,02092612 0,09882973 ! protein ubiquitination GO:0016567 125 77 2,000 0,02092612 0,09862721 ! regulation of transmission of nerve impulse GO:0051969 116 77 2,000 0,02092612 0,09842552 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 1,000 0,02174391 0,10206327 ! embryonic skeletal system morphogenesis GO:0048704 42 30 1,000 0,02174391 0,1018554 ! spindle organization GO:0007051 37 30 1,000 0,02174391 0,10164838 ! hindbrain development GO:0030902 45 30 1,000 0,02174391 0,1014422 ! establishment of vesicle localization GO:0051650 45 30 1,000 0,02174391 0,10123685 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 2,000 0,02312267 0,10743866 GO:0010498|proteasomal protein catabolic process, ! DNA damage checkpoint GO:0000077 53 31 1,000 0,0231293 0,1072528 ! negative regulation of secretion GO:0051048 49 31 1,000 0,0231293 0,107037 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 1,000 0,0231293 0,10682207 ! regulation of striated muscle tissue development GO:0016202 47 31 1,000 0,0231293 0,106608 ! mesoderm morphogenesis GO:0048332 49 31 1,000 0,0231293 0,10639478 ! hemostasis GO:0007599 125 81 2,000 0,02388166 0,10963637 ! regulation of neurological system process GO:0031644 122 81 2,000 0,02388166 0,10941797 ! positive regulation of cell activation GO:0050867 120 81 2,000 0,02388166 0,10920044 GO:0002696|positive regulation of leukocyte activation, ! regulation of muscle development GO:0048634 48 32 1,000 0,02455012 0,11203427 ! mitotic sister chromatid segregation GO:0000070 45 32 1,000 0,02455012 0,11181242 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 1,000 0,02455012 0,11159145 ! negative regulation of DNA metabolic process GO:0051053 48 32 1,000 0,02455012 0,11137135 ! peripheral nervous system development GO:0007422 53 32 1,000 0,02455012 0,11115211 ! regulation of protein stability GO:0031647 48 32 1,000 0,02455012 0,11093374 ! calcium-mediated signaling GO:0019722 50 32 1,000 0,02455012 0,11071622 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 1,000 0,02455012 0,11049956 ! vesicle localization GO:0051648 47 32 1,000 0,02455012 0,11028374 ! regulation of cell adhesion GO:0030155 159 83 2,000 0,02543984 0,11405778 ! positive regulation of DNA metabolic process GO:0051054 54 33 1,000 0,02600576 0,11636819 ! negative regulation of cell adhesion GO:0007162 67 33 1,000 0,02600576 0,11614223 ! sister chromatid segregation GO:0000819 46 33 1,000 0,02600576 0,11591715 ! carbohydrate homeostasis GO:0033500 39 33 1,000 0,02600576 0,11569294 GO:0042593|glucose homeostasis, ! nucleus organization GO:0006997 49 33 1,000 0,02600576 0,11546959 ! female gonad development GO:0008585 49 33 1,000 0,02600576 0,11524711 ! microtubule cytoskeleton organization GO:0000226 120 84 2,000 0,02623902 0,1160572 ! positive regulation of MAP kinase activity GO:0043406 121 85 2,000 0,02705157 0,11942152 ! negative regulation of multicellular organismal process GO:0051241 133 85 2,000 0,02705157 0,11919274 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 1,000 0,02749562 0,12091764 ! mitotic cell cycle checkpoint GO:0007093 63 34 1,000 0,02749562 0,12068689 ! DNA integrity checkpoint GO:0031570 57 34 1,000 0,02749562 0,12045701 ! erythrocyte homeostasis GO:0034101 45 34 1,000 0,02749562 0,120228 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 1,000 0,02749562 0,11999986 ! female gamete generation GO:0007292 43 34 1,000 0,02749562 0,11977259 ! aerobic respiration GO:0009060 47 34 1,000 0,02749562 0,11954618 ! dorsal/ventral pattern formation GO:0009953 44 34 1,000 0,02749562 0,11932062 ! Notch signaling pathway GO:0007219 56 35 1,000 0,0290191 0,1256948 ! glycogen metabolic process GO:0005977 48 35 1,000 0,0290191 0,12545853 ! protein homooligomerization GO:0051260 52 35 1,000 0,0290191 0,12522315 ! reproductive developmental process GO:0003006 127 89 2,000 0,03043521 0,131088 ! tissue remodeling GO:0048771 62 36 1,000 0,03057562 0,13144659 ! development of primary female sexual characteristics GO:0046545 52 36 1,000 0,03057562 0,13120135 GO:0046660|female sex differentiation, ! glucan metabolic process GO:0044042 49 36 1,000 0,03057562 0,13095703 GO:0006073|cellular glucan metabolic process, ! leukocyte differentiation GO:0002521 143 90 2,000 0,03131439 0,13387193 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 1,000 0,03216459 0,13725148 ! learning GO:0007612 67 37 1,000 0,03216459 0,13699731 ! regulation of protein secretion GO:0050708 51 37 1,000 0,03216459 0,13674408 ! DNA recombination GO:0006310 146 92 2,000 0,0331125 0,14051429 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 1,000 0,03378543 0,14310585 ! striated muscle cell differentiation GO:0051146 54 38 1,000 0,03378543 0,14284279 ! mesenchymal cell development GO:0014031 64 38 1,000 0,03378543 0,14258069 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! maintenance of location in cell GO:0051651 69 38 1,000 0,03378543 0,14231956 ! peptidyl-amino acid modification GO:0018193 147 93 2,000 0,03403137 0,14309353 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 1,000 0,03543757 0,14873433 ! male sex differentiation GO:0046661 53 39 1,000 0,03543757 0,14846341 ! JNK cascade GO:0007254 54 39 1,000 0,03543757 0,14819348 ! developmental growth GO:0048589 62 39 1,000 0,03543757 0,14792453 ! synapse organization GO:0050808 55 39 1,000 0,03543757 0,14765655 ! in utero embryonic development GO:0001701 147 96 2,000 0,03686692 0,15333438 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 1,000 0,03712046 0,15411021 ! regulation of myeloid cell differentiation GO:0045637 69 40 1,000 0,03712046 0,15383254 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 0,03746894 0,15499743 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 0,03746894 0,15471916 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 0,03746894 0,15444188 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 0,03746894 0,1541656 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 0,03746894 0,15389031 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,03746894 0,15361599 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 0,03746894 0,15334265 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 0,03746894 0,15307029 ! sleep GO:0030431 11 5 0,000 0,03746894 0,15279889 ! nucleotide-sugar transport GO:0015780 8 5 0,000 0,03746894 0,15252845 ! regulation of interferon-beta production GO:0032648 5 5 0,000 0,03746894 0,15225896 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 0,03746894 0,15199043 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 0,03746894 0,15172284 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 0,03746894 0,15145619 ! tongue development GO:0043586 6 5 0,000 0,03746894 0,15119048 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 0,03746894 0,15092569 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,03746894 0,15066184 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 0,03746894 0,1503989 ! cobalt ion transport GO:0006824 9 5 0,000 0,03746894 0,15013688 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 0,03746894 0,14987578 ! SMAD protein complex assembly GO:0007183 9 5 0,000 0,03746894 0,14961558 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 0,03746894 0,14935628 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 0,03746894 0,14909787 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 0,03746894 0,14884037 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 0,03746894 0,14858374 ! embryonic camera-type eye development GO:0031076 8 5 0,000 0,03746894 0,14832801 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 0,03746894 0,14807315 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 0,03746894 0,14781916 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,03746894 0,14756605 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,03746894 0,1473138 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 0,000 0,03746894 0,14706241 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 0,03746894 0,14681188 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,03746894 0,1465622 ! malate metabolic process GO:0006108 7 5 0,000 0,03746894 0,14631336 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 0,03746894 0,14606538 ! behavioral response to pain GO:0048266 7 5 0,000 0,03746894 0,14581823 ! clathrin coat assembly GO:0048268 11 5 0,000 0,03746894 0,14557191 ! phototransduction, visible light GO:0007603 6 5 0,000 0,03746894 0,14532643 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,03746894 0,14508177 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 0,03746894 0,14483794 ! mating behavior GO:0007617 6 5 0,000 0,03746894 0,14459492 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 0,03746894 0,14435272 ! rhythmic behavior GO:0007622 12 5 0,000 0,03746894 0,14411132 ! copulation GO:0007620 7 5 0,000 0,03746894 0,14387074 ! glial cell fate commitment GO:0021781 12 5 0,000 0,03746894 0,14363095 ! protein maturation by protein folding GO:0022417 12 5 0,000 0,03746894 0,14339197 ! embryonic hemopoiesis GO:0035162 10 5 0,000 0,03746894 0,14315377 ! regulation of potassium ion transport GO:0043266 9 5 0,000 0,03746894 0,14291637 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 0,03746894 0,14267975 ! apoptotic cell clearance GO:0043277 13 5 0,000 0,03746894 0,14244392 ! lipoprotein particle clearance GO:0034381 9 5 0,000 0,03746894 0,14220886 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 0,03746894 0,14197458 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,03746894 0,14174107 ! positive regulation of glycolysis GO:0045821 11 5 0,000 0,03746894 0,14150833 ! lymph vessel development GO:0001945 7 5 0,000 0,03746894 0,14127635 ! endochondral ossification GO:0001958 12 5 0,000 0,03746894 0,14104513 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 0,03746894 0,14081466 ! parathyroid gland development GO:0060017 8 5 0,000 0,03746894 0,14058495 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 0,03746894 0,14035598 ! anagen GO:0042640 6 5 0,000 0,03746894 0,14012776 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 0,03746894 0,13990028 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 0,03746894 0,13967354 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 0,03746894 0,13944753 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 0,03746894 0,13922225 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 0,03746894 0,1389977 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 0,03746894 0,13877387 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 0,03746894 0,13855076 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 0,03746894 0,13832837 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 0,03746894 0,13810669 ! cardiac muscle fiber development GO:0048739 7 5 0,000 0,03746894 0,13788571 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 0,03746894 0,13766545 ! negative regulation of survival gene product expression GO:0008634 6 5 0,000 0,03746894 0,13744589 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 0,03746894 0,13722702 ! ovulation GO:0030728 6 5 0,000 0,03746894 0,13700886 ! valine metabolic process GO:0006573 8 5 0,000 0,03746894 0,13679138 ! response to pH GO:0009268 9 5 0,000 0,03746894 0,1365746 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 0,03746894 0,1363585 ! proline biosynthetic process GO:0006561 6 5 0,000 0,03746894 0,13614308 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,03746894 0,13592835 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 0,03746894 0,13571429 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,03746894 0,1355009 ! polyol catabolic process GO:0046174 7 5 0,000 0,03746894 0,13528818 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,03746894 0,13507613 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,03746894 0,13486474 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,03746894 0,13465402 ! sister chromatid cohesion GO:0007062 9 5 0,000 0,03746894 0,13444395 ! nerve growth factor processing GO:0032455 7 5 0,000 0,03746894 0,13423454 ! urea metabolic process GO:0019627 6 5 0,000 0,03746894 0,13402577 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 0,03746894 0,13381766 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,03746894 0,13361019 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 0,000 0,03746894 0,13340336 ! neutrophil activation GO:0042119 5 5 0,000 0,03746894 0,13319717 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 0,03746894 0,13299162 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 0,03746894 0,1327867 ! response to food GO:0032094 5 5 0,000 0,03746894 0,13258242 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 0,03746894 0,13237876 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,03746894 0,13217572 ! paraxial mesoderm development GO:0048339 9 5 0,000 0,03746894 0,13197331 ! forebrain neuron development GO:0021884 7 5 0,000 0,03746894 0,13177152 ! melanosome organization GO:0032438 7 5 0,000 0,03746894 0,13157034 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 0,03746894 0,13136977 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,03746894 0,13116982 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 0,03746894 0,13097047 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,03746894 0,13077173 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 14 5 0,000 0,03746894 0,13057359 ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 0,03746894 0,13037605 ! nucleoside transport GO:0015858 6 5 0,000 0,03746894 0,13017911 ! nucleoside salvage GO:0043174 7 5 0,000 0,03746894 0,12998276 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 0,03746894 0,12978701 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,03746894 0,12959184 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 0,03746894 0,12939725 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 0,03746894 0,12920326 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,03746894 0,12900984 ! early endosome to late endosome transport GO:0045022 11 5 0,000 0,03746894 0,128817 ! depyrimidination GO:0045008 8 5 0,000 0,03746894 0,12862473 ! 5S class rRNA transcription GO:0042791 8 5 0,000 0,03746894 0,12843304 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 0,03746894 0,12824192 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,03746894 0,12805137 ! neuronal ion channel clustering GO:0045161 7 5 0,000 0,03746894 0,12786138 ! sodium ion homeostasis GO:0055078 6 5 0,000 0,03746894 0,12767196 ! homeostasis of number of cells within a tissue GO:0048873 9 5 0,000 0,03746894 0,12748309 ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 0,03746894 0,12729479 ! monocyte differentiation GO:0030224 8 5 0,000 0,03746894 0,12710704 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 0,03746894 0,12691984 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 0,03746894 0,12673319 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 0,03746894 0,12654709 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 0,03746894 0,12636154 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 0,03746894 0,12617653 ! regulation of dendrite development GO:0050773 12 5 0,000 0,03746894 0,12599206 ! peptidyl-arginine modification GO:0018195 7 5 0,000 0,03746894 0,12580813 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,03746894 0,12562474 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 0,03746894 0,12544188 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 0,03746894 0,12525955 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 0,03746894 0,12507775 ! regulation of dopamine secretion GO:0014059 12 5 0,000 0,03746894 0,12489648 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 0,03746894 0,12471573 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 0,03746894 0,12453551 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,03746894 0,1243558 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 0,03746894 0,12417662 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,03746894 0,12399794 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 0,03746894 0,12381979 ! positive regulation of Rho GTPase activity GO:0032321 9 5 0,000 0,03746894 0,12364214 ! neural tube patterning GO:0021532 6 5 0,000 0,03746894 0,123465 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 0,03746894 0,12328837 ! histone demethylation GO:0016577 9 5 0,000 0,03746894 0,12311224 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,03746894 0,12293662 ! regulation of sterol transport GO:0032371 7 5 0,000 0,03746894 0,1227615 GO:0032374|regulation of cholesterol transport, ! enteric nervous system development GO:0048484 8 5 0,000 0,03746894 0,12258687 ! establishment of planar polarity GO:0001736 6 5 0,000 0,03746894 0,12241274 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 0,03746894 0,12223911 ! muscle cell proliferation GO:0033002 8 5 0,000 0,03746894 0,12206597 ! transcription termination GO:0006353 8 5 0,000 0,03746894 0,12189331 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 0,03746894 0,12172115 ! plasminogen activation GO:0031639 5 5 0,000 0,03746894 0,12154947 ! regulation of respiratory burst GO:0060263 8 5 0,000 0,03746894 0,12137827 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 0,03746894 0,12120755 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,03746894 0,12103732 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,03746894 0,12086756 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 0,03746894 0,12069828 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 0,03746894 0,12052947 ! apical protein localization GO:0045176 6 5 0,000 0,03746894 0,12036113 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 0,03746894 0,12019327 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 0,03746894 0,12002587 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,03746894 0,11985893 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 0,03746894 0,11969246 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 0,03746894 0,11952645 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 0,03746894 0,1193609 ! triglyceride catabolic process GO:0019433 6 5 0,000 0,03746894 0,11919581 ! glial cell migration GO:0008347 10 5 0,000 0,03746894 0,11903118 ! determination of adult lifespan GO:0008340 8 5 0,000 0,03746894 0,118867 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 0,03746894 0,11870327 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,03746894 0,11853999 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,03746894 0,11837716 ! somatic stem cell maintenance GO:0035019 13 5 0,000 0,03746894 0,11821478 ! cerebellar cortex formation GO:0021697 6 5 0,000 0,03746894 0,11805284 ! neural plate development GO:0001840 6 5 0,000 0,03746894 0,11789134 ! regulation of sensory perception GO:0051931 6 5 0,000 0,03746894 0,11773029 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 0,03746894 0,11756967 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 0,03746894 0,1174095 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 10 5 0,000 0,03746894 0,11724976 ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 0,03746894 0,11709045 ! sensory cilium assembly GO:0035058 6 5 0,000 0,03746894 0,11693158 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 0,03746894 0,11677313 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,03746894 0,11661512 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 0,03746894 0,11645753 ! spindle assembly GO:0051225 5 5 0,000 0,03746894 0,11630037 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 0,03746894 0,11614363 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 0,03746894 0,11598731 ! protein amino acid prenylation GO:0018346 9 5 0,000 0,03746894 0,11583141 ! organ regeneration GO:0031100 7 5 0,000 0,03746894 0,11567593 ! NAD biosynthetic process GO:0009435 7 5 0,000 0,03746894 0,11552087 ! carnitine metabolic process GO:0009437 5 5 0,000 0,03746894 0,11536623 GO:0006577|betaine metabolic process, ! positive regulation of microtubule polymerization GO:0031116 9 5 0,000 0,03746894 0,11521199 ! cellular anion homeostasis GO:0030002 6 5 0,000 0,03746894 0,11505817 GO:0055081|anion homeostasis, ! epithelial cell differentiation GO:0030855 55 41 1,000 0,03883354 0,11908951 ! energy reserve metabolic process GO:0006112 59 41 1,000 0,03883354 0,11893094 ! glucose transport GO:0015758 52 41 1,000 0,03883354 0,11877278 ! regulation of JAK-STAT cascade GO:0046425 61 42 1,000 0,04057625 0,12393808 ! cellular component disassembly GO:0022411 64 42 1,000 0,04057625 0,12377371 ! hexose transport GO:0008645 54 42 1,000 0,04057625 0,12360977 GO:0015749|monosaccharide transport, ! embryonic skeletal system development GO:0048706 56 42 1,000 0,04057625 0,12344627 ! regulation of cell shape GO:0008360 78 42 1,000 0,04057625 0,12328319 ! regulation of body fluid levels GO:0050878 154 100 2,000 0,04083044 0,12389185 ! activation of caspase activity GO:0006919 65 43 1,000 0,04234806 0,12832746 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 1,000 0,04234806 0,1281586 ! vesicle organization GO:0016050 79 43 1,000 0,04234806 0,1279902 ! glycolysis GO:0006096 53 44 1,000 0,04414843 0,13325642 ! negative regulation of cell migration GO:0030336 92 44 1,000 0,04414843 0,13308177 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 1,000 0,04414843 0,13290758 ! tRNA transcription GO:0009304 11 6 0,000 0,04479381 0,13467419 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 0,04479381 0,13449838 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 8 6 0,000 0,04479381 0,13432302 ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 0,04479381 0,13414812 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,04479381 0,13397368 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 0,04479381 0,13379968 ! regulation of helicase activity GO:0051095 11 6 0,000 0,04479381 0,13362614 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 0,04479381 0,13345305 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 0,04479381 0,13328041 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 0,04479381 0,13310821 ! positive regulation of axon extension GO:0045773 8 6 0,000 0,04479381 0,13293646 ! prostate gland development GO:0030850 9 6 0,000 0,04479381 0,13276515 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 0,04479381 0,13259428 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 0,04479381 0,13242385 ! forebrain neuron differentiation GO:0021879 9 6 0,000 0,04479381 0,13225386 GO:0021872|generation of neurons in the forebrain, ! regulation of lipid catabolic process GO:0050994 9 6 0,000 0,04479381 0,1320843 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 0,04479381 0,13191518 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 0,04479381 0,13174649 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 0,04479381 0,13157823 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 0,04479381 0,1314104 ! neuron adhesion GO:0007158 9 6 0,000 0,04479381 0,131243 ! establishment of tissue polarity GO:0007164 7 6 0,000 0,04479381 0,13107603 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 0,04479381 0,13090947 ! signal peptide processing GO:0006465 8 6 0,000 0,04479381 0,13074335 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 0,04479381 0,13057764 ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 0,04479381 0,13041235 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 0,04479381 0,13024748 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 0,04479381 0,13008303 ! opsonization GO:0008228 8 6 0,000 0,04479381 0,12991899 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 0,04479381 0,12975536 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 0,04479381 0,12959215 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 0,04479381 0,12942934 ! protein amino acid dealkylation GO:0008214 11 6 0,000 0,04479381 0,12926695 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 0,04479381 0,12910496 ! photoreceptor cell development GO:0042461 10 6 0,000 0,04479381 0,12894337 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 0,04479381 0,1287822 ! mechanosensory behavior GO:0007638 8 6 0,000 0,04479381 0,12862142 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 0,04479381 0,12846104 ! negative regulation of endocytosis GO:0045806 8 6 0,000 0,04479381 0,12830107 ! response to interferon-gamma GO:0034341 12 6 0,000 0,04479381 0,12814149 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 0,04479381 0,12798231 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 0,04479381 0,12782352 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,04479381 0,12766513 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 0,04479381 0,12750712 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 0,04479381 0,12734951 ! cGMP-mediated signaling GO:0019934 10 6 0,000 0,04479381 0,12719229 ! activation of MAPKKK activity GO:0000185 10 6 0,000 0,04479381 0,12703546 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 0,04479381 0,12687901 ! thymic T cell selection GO:0045061 12 6 0,000 0,04479381 0,12672295 ! protein lipoylation GO:0009249 10 6 0,000 0,04479381 0,12656727 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 0,04479381 0,12641197 ! pigment granule organization GO:0048753 11 6 0,000 0,04479381 0,12625705 ! cysteine metabolic process GO:0006534 7 6 0,000 0,04479381 0,12610252 ! activation of caspase activity by cytochrome c GO:0008635 10 6 0,000 0,04479381 0,12594836 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 0,04479381 0,12579457 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,04479381 0,12564117 ! histidine metabolic process GO:0006547 6 6 0,000 0,04479381 0,12548813 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 0,04479381 0,12533547 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 0,04479381 0,12518318 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 0,000 0,04479381 0,12503126 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! glycine catabolic process GO:0006546 9 6 0,000 0,04479381 0,1248797 ! adenohypophysis development GO:0021984 10 6 0,000 0,04479381 0,12472852 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 0,04479381 0,1245777 ! hyperosmotic response GO:0006972 8 6 0,000 0,04479381 0,12442724 ! microtubule nucleation GO:0007020 10 6 0,000 0,04479381 0,12427715 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 0,04479381 0,12412742 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 0,04479381 0,12397805 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 0,04479381 0,12382903 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 0,04479381 0,12368038 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 0,04479381 0,12353208 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! response to dietary excess GO:0002021 7 6 0,000 0,04479381 0,12338414 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 0,04479381 0,12323655 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 0,04479381 0,12308931 ! glycerol ether catabolic process GO:0044269 8 6 0,000 0,04479381 0,12294243 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 0,04479381 0,1227959 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,04479381 0,12264971 ! neuron apoptosis GO:0051402 8 6 0,000 0,04479381 0,12250387 ! organic alcohol transport GO:0015850 9 6 0,000 0,04479381 0,12235838 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 0,000 0,04479381 0,12221323 ! T cell mediated immunity GO:0002456 12 6 0,000 0,04479381 0,12206843 ! male sex determination GO:0030238 9 6 0,000 0,04479381 0,12192397 ! carnitine transport GO:0015879 8 6 0,000 0,04479381 0,12177985 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 0,04479381 0,12163608 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 0,04479381 0,12149264 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 0,04479381 0,12134954 ! positive regulation of exocytosis GO:0045921 6 6 0,000 0,04479381 0,12120677 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 0,04479381 0,12106434 ! parturition GO:0007567 12 6 0,000 0,04479381 0,12092225 ! negative regulation of translational initiation GO:0045947 7 6 0,000 0,04479381 0,12078049 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 0,04479381 0,12063906 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 0,04479381 0,12049796 ! spindle checkpoint GO:0031577 14 6 0,000 0,04479381 0,12035719 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 0,04479381 0,12021675 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 0,04479381 0,12007664 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 0,04479381 0,11993685 ! astrocyte development GO:0014002 14 6 0,000 0,04479381 0,11979739 ! hyaluronan metabolic process GO:0030212 6 6 0,000 0,04479381 0,11965825 ! purine base biosynthetic process GO:0009113 14 6 0,000 0,04479381 0,11951944 ! interaction with symbiont GO:0051702 8 6 0,000 0,04479381 0,11938095 ! anterograde axon cargo transport GO:0008089 8 6 0,000 0,04479381 0,11924277 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,04479381 0,11910492 ! eating behavior GO:0042755 6 6 0,000 0,04479381 0,11896739 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 0,04479381 0,11883017 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 0,04479381 0,11869327 ! response to copper ion GO:0046688 9 6 0,000 0,04479381 0,11855668 ! DNA topological change GO:0006265 8 6 0,000 0,04479381 0,11842041 ! response to exogenous dsRNA GO:0043330 8 6 0,000 0,04479381 0,11828445 ! establishment of melanosome localization GO:0032401 9 6 0,000 0,04479381 0,1181488 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,04479381 0,11801347 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,04479381 0,11787844 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 0,04479381 0,11774372 ! negative regulation of focal adhesion formation GO:0051895 16 6 0,000 0,04479381 0,11760931 ! nucleoside catabolic process GO:0009164 6 6 0,000 0,04479381 0,11747521 ! gas homeostasis GO:0033483 11 6 0,000 0,04479381 0,11734141 ! hair follicle maturation GO:0048820 7 6 0,000 0,04479381 0,11720791 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 0,04479381 0,11707472 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 0,04479381 0,11694183 ! Schwann cell development GO:0014044 14 6 0,000 0,04479381 0,11680925 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 0,04479381 0,11667696 ! dendrite morphogenesis GO:0048813 9 6 0,000 0,04479381 0,11654497 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,04479381 0,11641328 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 0,04479381 0,11628189 ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 0,04479381 0,1161508 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 0,04479381 0,11602 ! histone ubiquitination GO:0016574 7 6 0,000 0,04479381 0,11588949 ! regulation of meiosis GO:0040020 10 6 0,000 0,04479381 0,11575928 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 0,04479381 0,11562936 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 0,04479381 0,11549973 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 0,04479381 0,11537039 ! regulation of mast cell activation GO:0033003 6 6 0,000 0,04479381 0,11524134 ! membrane to membrane docking GO:0022614 12 6 0,000 0,04479381 0,11511258 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 0,04479381 0,1149841 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 0,04479381 0,11485592 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 0,04479381 0,11472801 ! receptor internalization GO:0031623 9 6 0,000 0,04479381 0,1146004 ! coenzyme A metabolic process GO:0015936 9 6 0,000 0,04479381 0,11447306 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,04479381 0,11434601 GO:0043011|myeloid dendritic cell differentiation, ! protein deubiquitination GO:0016579 8 6 0,000 0,04479381 0,11421924 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 0,04479381 0,11409275 ! negative regulation of neuroblast proliferation GO:0007406 18 6 0,000 0,04479381 0,11396654 ! peptidyl-histidine modification GO:0018202 9 6 0,000 0,04479381 0,11384061 ! axonal fasciculation GO:0007413 9 6 0,000 0,04479381 0,11371496 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 0,04479381 0,11358959 ! thiamin metabolic process GO:0006772 6 6 0,000 0,04479381 0,11346449 ! midbrain development GO:0030901 6 6 0,000 0,04479381 0,11333967 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 0,04479381 0,11321512 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,04479381 0,11309084 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 0,04479381 0,11296684 ! progesterone metabolic process GO:0042448 8 6 0,000 0,04479381 0,11284311 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 0,04479381 0,11271965 ! glycolipid catabolic process GO:0019377 13 6 0,000 0,04479381 0,11259646 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 0,04479381 0,11247353 ! positive regulation of glucose import GO:0046326 6 6 0,000 0,04479381 0,11235088 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 0,04479381 0,11222849 ! adult feeding behavior GO:0008343 6 6 0,000 0,04479381 0,11210637 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 0,04479381 0,11198452 ! pigment granule transport GO:0051904 12 6 0,000 0,04479381 0,11186293 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 0,04479381 0,1117416 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 0,04479381 0,11162054 ! catecholamine transport GO:0051937 7 6 0,000 0,04479381 0,11149974 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 0,04479381 0,1113792 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 0,04479381 0,11125892 ! protein prenylation GO:0018342 10 6 0,000 0,04479381 0,1111389 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,04479381 0,11101913 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 0,000 0,04479381 0,11089963 ! regulation of microtubule polymerization GO:0031113 11 6 0,000 0,04479381 0,11078038 ! positive regulation of coagulation GO:0050820 11 6 0,000 0,04479381 0,11066139 ! vascular process in circulatory system GO:0003018 69 45 1,000 0,04597683 0,11346213 ! cell maturation GO:0048469 60 45 1,000 0,04597683 0,11334052 ! histone modification GO:0016570 68 46 1,000 0,04783273 0,11778939 ! regulation of adaptive immune response GO:0002819 72 46 1,000 0,04783273 0,11766341 ! response to estrogen stimulus GO:0043627 74 47 1,000 0,04971563 0,12216447 ! endocrine system development GO:0035270 83 47 1,000 0,04971563 0,12203409 ! covalent chromatin modification GO:0016569 75 47 1,000 0,04971563 0,12190399 ! positive regulation of caspase activity GO:0043280 72 48 1,000 0,051625 0,12645101 GO:0010952|positive regulation of peptidase activity, ! cellular polysaccharide metabolic process GO:0044264 63 48 1,000 0,051625 0,12631649 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 1,000 0,051625 0,12618225 ! positive regulation of cytokine production GO:0001819 73 48 1,000 0,051625 0,1260483 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 0,05206334 0,12698377 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 0,05206334 0,12684925 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 0,05206334 0,12671502 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 0,05206334 0,12658107 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 0,05206334 0,1264474 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,05206334 0,12631402 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 0,05206334 0,12618092 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,05206334 0,1260481 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 0,05206334 0,12591555 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 0,05206334 0,12578329 ! reproductive behavior GO:0019098 12 7 0,000 0,05206334 0,1256513 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 0,05206334 0,12551959 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 0,05206334 0,12538816 ! regulation of smooth muscle cell migration GO:0014910 19 7 0,000 0,05206334 0,125257 ! protein amino acid sulfation GO:0006477 9 7 0,000 0,05206334 0,12512611 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 0,05206334 0,1249955 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! negative regulation of JAK-STAT cascade GO:0046426 15 7 0,000 0,05206334 0,12486516 ! RNA methylation GO:0001510 11 7 0,000 0,05206334 0,12473509 ! pericardium development GO:0060039 8 7 0,000 0,05206334 0,1246053 ! macrophage chemotaxis GO:0048246 10 7 0,000 0,05206334 0,12447577 ! fibril organization GO:0043206 13 7 0,000 0,05206334 0,12434651 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 0,05206334 0,12421752 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,05206334 0,1240888 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 0,05206334 0,12396034 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 0,05206334 0,12383215 ! lipoprotein transport GO:0042953 9 7 0,000 0,05206334 0,12370423 ! cerebral cortex cell migration GO:0021795 11 7 0,000 0,05206334 0,12357656 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,05206334 0,12344917 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,05206334 0,12332203 ! estrogen metabolic process GO:0008210 14 7 0,000 0,05206334 0,12319516 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 0,05206334 0,12306854 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 0,05206334 0,12294219 ! chemosensory behavior GO:0007635 9 7 0,000 0,05206334 0,12281609 ! microtubule bundle formation GO:0001578 8 7 0,000 0,05206334 0,12269026 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 0,05206334 0,12256468 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 0,05206334 0,12243936 ! leukocyte degranulation GO:0043299 10 7 0,000 0,05206334 0,12231429 ! bile acid and bile salt transport GO:0015721 9 7 0,000 0,05206334 0,12218948 ! reflex GO:0060004 12 7 0,000 0,05206334 0,12206492 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,05206334 0,12194062 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 0,05206334 0,12181657 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,05206334 0,12169278 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 0,05206334 0,12156923 ! glycerolipid catabolic process GO:0046503 9 7 0,000 0,05206334 0,12144593 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,05206334 0,12132289 ! spinal cord patterning GO:0021511 7 7 0,000 0,05206334 0,12120009 ! hemoglobin metabolic process GO:0020027 10 7 0,000 0,05206334 0,12107754 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 0,05206334 0,12095524 ! adrenal gland development GO:0030325 17 7 0,000 0,05206334 0,12083319 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 0,05206334 0,12071138 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 0,05206334 0,12058982 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 0,05206334 0,1204685 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 0,05206334 0,12034743 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 0,05206334 0,1202266 ! endosome organization GO:0007032 10 7 0,000 0,05206334 0,12010601 ! thyroid hormone generation GO:0006590 11 7 0,000 0,05206334 0,11998566 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 0,05206334 0,11986556 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 0,05206334 0,11974569 ! regulation of pigmentation during development GO:0048070 15 7 0,000 0,05206334 0,11962606 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,05206334 0,11950668 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 0,05206334 0,11938753 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,05206334 0,11926862 ! galactose metabolic process GO:0006012 10 7 0,000 0,05206334 0,11914994 ! intracellular pH reduction GO:0051452 10 7 0,000 0,05206334 0,1190315 GO:0045851|pH reduction, ! asymmetric protein localization GO:0008105 8 7 0,000 0,05206334 0,1189133 ! organ growth GO:0035265 11 7 0,000 0,05206334 0,11879533 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 0,05206334 0,11867759 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 0,000 0,05206334 0,11856009 ! Rac protein signal transduction GO:0016601 7 7 0,000 0,05206334 0,11844282 ! retinol metabolic process GO:0042572 9 7 0,000 0,05206334 0,11832578 ! behavioral fear response GO:0001662 13 7 0,000 0,05206334 0,11820897 GO:0002209|behavioral defense response, ! negative regulation of muscle contraction GO:0045932 12 7 0,000 0,05206334 0,1180924 ! rRNA modification GO:0000154 12 7 0,000 0,05206334 0,11797605 ! protein heterooligomerization GO:0051291 10 7 0,000 0,05206334 0,11785993 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,05206334 0,11774404 ! response to UV-B GO:0010224 11 7 0,000 0,05206334 0,11762838 ! G1 DNA damage checkpoint GO:0031571 18 7 0,000 0,05206334 0,11751294 ! protein retention in ER lumen GO:0006621 12 7 0,000 0,05206334 0,11739774 ! intermediate filament organization GO:0045109 11 7 0,000 0,05206334 0,11728275 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 0,05206334 0,11716799 ! cardiac muscle cell development GO:0055013 9 7 0,000 0,05206334 0,11705346 ! fibrinolysis GO:0042730 9 7 0,000 0,05206334 0,11693915 ! regulation of circadian rhythm GO:0042752 11 7 0,000 0,05206334 0,11682506 ! B cell lineage commitment GO:0002326 17 7 0,000 0,05206334 0,1167112 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 0,05206334 0,11659756 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 0,05206334 0,11648414 ! response to tropane GO:0014073 13 7 0,000 0,05206334 0,11637093 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 0,05206334 0,11625795 ! melanosome localization GO:0032400 10 7 0,000 0,05206334 0,11614519 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 0,05206334 0,11603265 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 0,05206334 0,11592032 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 0,05206334 0,11580821 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 0,05206334 0,11569632 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 0,05206334 0,11558464 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 0,05206334 0,11547318 ! mast cell activation GO:0045576 9 7 0,000 0,05206334 0,11536194 ! multicellular organismal aging GO:0010259 11 7 0,000 0,05206334 0,11525091 ! regulation of focal adhesion formation GO:0051893 17 7 0,000 0,05206334 0,11514009 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 0,05206334 0,11502948 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 0,05206334 0,11491909 ! positive regulation of monooxygenase activity GO:0032770 11 7 0,000 0,05206334 0,11480891 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 0,05206334 0,11469894 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 0,05206334 0,11458918 ! T cell lineage commitment GO:0002360 12 7 0,000 0,05206334 0,11447963 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 0,05206334 0,11437029 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 0,05206334 0,11426116 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 0,05206334 0,11415223 ! regulation of lipid transport GO:0032368 13 7 0,000 0,05206334 0,11404352 ! response to tumor cell GO:0002347 12 7 0,000 0,05206334 0,11393501 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 0,05206334 0,1138267 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 0,05206334 0,1137186 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 0,000 0,05206334 0,11361071 ! peptidyl-threonine modification GO:0018210 18 7 0,000 0,05206334 0,11350302 ! diuresis GO:0030146 12 7 0,000 0,05206334 0,11339554 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 0,05206334 0,11328826 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of epidermis development GO:0045684 11 7 0,000 0,05206334 0,11318118 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,05206334 0,11307431 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,05206334 0,11296763 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,05206334 0,11286116 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 0,05206334 0,11275489 ! dopamine biosynthetic process GO:0042416 15 7 0,000 0,05206334 0,11264882 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 0,05206334 0,11254294 ! lymph node development GO:0048535 9 7 0,000 0,05206334 0,11243727 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 0,05206334 0,11233179 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 0,05206334 0,11222651 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,05206334 0,11212143 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 0,05206334 0,11201655 ! endosome to lysosome transport GO:0008333 10 7 0,000 0,05206334 0,11191186 ! ATP catabolic process GO:0006200 10 7 0,000 0,05206334 0,11180737 ! establishment of pigment granule localization GO:0051905 13 7 0,000 0,05206334 0,11170307 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 0,05206334 0,11159897 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 0,05206334 0,11149506 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 0,05206334 0,11139134 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 0,05206334 0,11128782 ! muscle adaptation GO:0043500 12 7 0,000 0,05206334 0,11118449 ! amino sugar catabolic process GO:0046348 9 7 0,000 0,05206334 0,11108135 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 0,05206334 0,1109784 ! retina homeostasis GO:0001895 9 7 0,000 0,05206334 0,11087564 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 0,05206334 0,11077307 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 0,05206334 0,11067069 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 0,05206334 0,1105685 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 0,05206334 0,1104665 ! behavioral response to nicotine GO:0035095 11 7 0,000 0,05206334 0,11036469 ! germ cell development GO:0007281 68 49 1,000 0,05356034 0,11343351 ! integrin-mediated signaling pathway GO:0007229 81 49 1,000 0,05356034 0,11332915 ! maintenance of location GO:0051235 84 49 1,000 0,05356034 0,11322499 ! lipid modification GO:0030258 73 50 1,000 0,05552116 0,11726232 ! regulation of protein catabolic process GO:0042176 77 51 1,000 0,05750696 0,12134496 ! positive regulation of organelle organization GO:0010638 82 51 1,000 0,05750696 0,12123373 ! negative regulation of cell motion GO:0051271 104 51 1,000 0,05750696 0,12112272 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 0,05927797 0,12473864 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,05927797 0,12462461 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! axon extension GO:0048675 11 8 0,000 0,05927797 0,1245108 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 0,000 0,05927797 0,1243972 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 0,05927797 0,1242838 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 0,000 0,05927797 0,12417061 GO:0046579|positive regulation of Ras protein signal transduction, ! associative learning GO:0008306 15 8 0,000 0,05927797 0,12405762 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,05927797 0,12394484 ! cell proliferation in forebrain GO:0021846 10 8 0,000 0,05927797 0,12383227 ! phosphate transport GO:0006817 10 8 0,000 0,05927797 0,1237199 ! N-glycan processing GO:0006491 12 8 0,000 0,05927797 0,12360773 ! UTP metabolic process GO:0046051 8 8 0,000 0,05927797 0,12349577 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 0,05927797 0,12338401 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 0,05927797 0,12327245 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 10 8 0,000 0,05927797 0,12316109 ! succinate metabolic process GO:0006105 14 8 0,000 0,05927797 0,12304994 ! smoothened signaling pathway GO:0007224 8 8 0,000 0,05927797 0,12293898 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,05927797 0,12282822 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 0,000 0,05927797 0,12271767 ! keratinocyte proliferation GO:0043616 12 8 0,000 0,05927797 0,12260731 ! middle ear morphogenesis GO:0042474 9 8 0,000 0,05927797 0,12249715 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,05927797 0,12238719 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,05927797 0,12227742 ! ganglioside metabolic process GO:0001573 15 8 0,000 0,05927797 0,12216786 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 0,000 0,05927797 0,12205849 ! pseudouridine synthesis GO:0001522 9 8 0,000 0,05927797 0,12194931 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,05927797 0,12184033 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,05927797 0,12173154 ! endothelial cell differentiation GO:0045446 14 8 0,000 0,05927797 0,12162295 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,05927797 0,12151455 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 0,000 0,05927797 0,12140635 ! astrocyte differentiation GO:0048708 16 8 0,000 0,05927797 0,12129834 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 0,05927797 0,12119051 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,05927797 0,12108289 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,05927797 0,12097545 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 0,05927797 0,1208682 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,05927797 0,12076114 ! melanin metabolic process GO:0006582 12 8 0,000 0,05927797 0,12065427 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 0,05927797 0,12054759 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,05927797 0,1204411 ! macrophage activation GO:0042116 12 8 0,000 0,05927797 0,1203348 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,05927797 0,12022868 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,05927797 0,12012276 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! neurotransmitter catabolic process GO:0042135 13 8 0,000 0,05927797 0,12001701 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 0,05927797 0,11991146 ! ruffle organization GO:0031529 11 8 0,000 0,05927797 0,11980609 ! lens development in camera-type eye GO:0002088 10 8 0,000 0,05927797 0,1197009 ! positive regulation of vasodilation GO:0045909 12 8 0,000 0,05927797 0,1195959 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,05927797 0,11949109 ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 0,05927797 0,11938645 ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 0,05927797 0,119282 ! Schwann cell differentiation GO:0014037 17 8 0,000 0,05927797 0,11917773 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,05927797 0,11907365 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 0,05927797 0,11896975 ! brain morphogenesis GO:0048854 20 8 0,000 0,05927797 0,11886602 ! oligodendrocyte development GO:0014003 8 8 0,000 0,05927797 0,11876248 ! segment specification GO:0007379 10 8 0,000 0,05927797 0,11865912 ! cellular extravasation GO:0045123 11 8 0,000 0,05927797 0,11855594 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 0,05927797 0,11845294 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 0,05927797 0,11835011 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 0,05927797 0,11824747 ! snRNA metabolic process GO:0016073 10 8 0,000 0,05927797 0,118145 GO:0016180|snRNA processing, ! regulation of interleukin-4 production GO:0032673 16 8 0,000 0,05927797 0,11804271 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 0,05927797 0,1179406 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,05927797 0,11783866 ! regulation of mitochondrial membrane potential GO:0051881 11 8 0,000 0,05927797 0,1177369 ! nucleosome disassembly GO:0006337 12 8 0,000 0,05927797 0,11763531 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 0,05927797 0,1175339 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of Ras GTPase activity GO:0032320 20 8 0,000 0,05927797 0,11743267 ! protein import into peroxisome matrix GO:0016558 14 8 0,000 0,05927797 0,11733161 ! icosanoid secretion GO:0032309 12 8 0,000 0,05927797 0,11723072 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 11 8 0,000 0,05927797 0,11713001 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,05927797 0,11702947 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 0,05927797 0,1169291 ! cerebellum morphogenesis GO:0021587 9 8 0,000 0,05927797 0,1168289 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 0,05927797 0,11672888 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 0,05927797 0,11662902 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 0,05927797 0,11652934 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 0,05927797 0,11642983 ! sterol catabolic process GO:0016127 9 8 0,000 0,05927797 0,11633049 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 0,05927797 0,11623131 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 0,05927797 0,11613231 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 0,05927797 0,11603347 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 0,05927797 0,1159348 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,05927797 0,1158363 ! prophase GO:0051324 11 8 0,000 0,05927797 0,11573797 ! S phase GO:0051320 8 8 0,000 0,05927797 0,1156398 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 0,05927797 0,1155418 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,05927797 0,11544397 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,05927797 0,1153463 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,05927797 0,1152488 ! hormone catabolic process GO:0042447 13 8 0,000 0,05927797 0,11515146 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,05927797 0,11505429 ! regulation of fibrinolysis GO:0051917 13 8 0,000 0,05927797 0,11495728 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 0,05927797 0,11486043 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,05927797 0,11476374 ! regulation of telomere maintenance GO:0032204 10 8 0,000 0,05927797 0,11466722 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,05927797 0,11457086 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,05927797 0,11447467 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 0,05927797 0,11437863 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 0,05927797 0,11428276 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,05927797 0,11418704 ! lamellipodium assembly GO:0030032 9 8 0,000 0,05927797 0,11409149 ! regulation of embryonic development GO:0045995 16 8 0,000 0,05927797 0,11399609 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,05927797 0,11390086 GO:0000076|DNA replication checkpoint, ! mitochondrion localization GO:0051646 12 8 0,000 0,05927797 0,11380578 ! single fertilization GO:0007338 59 53 1,000 0,06155155 0,11807221 ! amino acid transport GO:0006865 84 54 1,000 0,06360939 0,12191801 ! glucose catabolic process GO:0006007 66 54 1,000 0,06360939 0,12181649 ! DNA catabolic process GO:0006308 67 54 1,000 0,06360939 0,12171515 ! regulation of mitosis GO:0007088 84 54 1,000 0,06360939 0,12161397 GO:0051783|regulation of nuclear division, ! cytokine-mediated signaling pathway GO:0019221 76 54 1,000 0,06360939 0,12151296 ! exocytosis GO:0006887 74 55 1,000 0,0656903 0,12538398 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,06643809 0,12670615 ! positive regulation of glucose metabolic process GO:0010907 15 9 0,000 0,06643809 0,12660117 ! telencephalon cell migration GO:0022029 16 9 0,000 0,06643809 0,12649637 ! regulation of epithelial cell differentiation GO:0030856 13 9 0,000 0,06643809 0,12639174 ! pentose-phosphate shunt GO:0006098 12 9 0,000 0,06643809 0,12628729 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 0,06643809 0,126183 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 0,06643809 0,12607889 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,06643809 0,12597495 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! positive regulation of GTPase activity GO:0043547 21 9 0,000 0,06643809 0,12587118 ! SMAD protein nuclear translocation GO:0007184 15 9 0,000 0,06643809 0,12576759 ! GTP metabolic process GO:0046039 9 9 0,000 0,06643809 0,12566416 ! elastic fiber assembly GO:0048251 13 9 0,000 0,06643809 0,1255609 ! social behavior GO:0035176 14 9 0,000 0,06643809 0,12545781 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 0,06643809 0,1253549 ! artery development GO:0060840 19 9 0,000 0,06643809 0,12525215 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 0,06643809 0,12514956 ! regulation of glycolysis GO:0006110 15 9 0,000 0,06643809 0,12504715 ! response to pain GO:0048265 16 9 0,000 0,06643809 0,1249449 ! protein complex disassembly GO:0043241 17 9 0,000 0,06643809 0,12484282 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,06643809 0,12474091 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,06643809 0,12463917 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 0,06643809 0,12453759 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,06643809 0,12443617 ! negative regulation of striated muscle development GO:0045843 11 9 0,000 0,06643809 0,12433492 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,06643809 0,12423383 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,06643809 0,12413291 ! ventral spinal cord development GO:0021517 11 9 0,000 0,06643809 0,12403216 ! protein targeting to ER GO:0045047 19 9 0,000 0,06643809 0,12393156 ! T cell selection GO:0045058 18 9 0,000 0,06643809 0,12383113 ! endoderm development GO:0007492 12 9 0,000 0,06643809 0,12373086 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,06643809 0,12363076 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,06643809 0,12353081 ! arginine catabolic process GO:0006527 10 9 0,000 0,06643809 0,12343103 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 0,06643809 0,12333141 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 0,06643809 0,12323195 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,06643809 0,12313265 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 12 9 0,000 0,06643809 0,12303351 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 0,06643809 0,12293453 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 0,000 0,06643809 0,1228357 ! regulation of stress fiber formation GO:0051492 20 9 0,000 0,06643809 0,12273704 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,06643809 0,12263854 ! mannose metabolic process GO:0006013 9 9 0,000 0,06643809 0,12254019 ! substrate-bound cell migration GO:0006929 10 9 0,000 0,06643809 0,122442 ! receptor clustering GO:0043113 15 9 0,000 0,06643809 0,12234397 ! epithelial cell development GO:0002064 10 9 0,000 0,06643809 0,12224609 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 0,06643809 0,12214837 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,06643809 0,12205081 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 0,06643809 0,12195341 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,06643809 0,12185615 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 0,06643809 0,12175906 ! alpha-beta T cell differentiation GO:0046632 14 9 0,000 0,06643809 0,12166212 ! positive regulation of phagocytosis GO:0050766 11 9 0,000 0,06643809 0,12156533 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,06643809 0,12146869 ! DNA ligation GO:0006266 14 9 0,000 0,06643809 0,12137221 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 0,06643809 0,12127589 ! response to amine stimulus GO:0014075 13 9 0,000 0,06643809 0,12117971 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 0,06643809 0,12108369 ! erythrocyte development GO:0048821 11 9 0,000 0,06643809 0,12098782 ! renal water homeostasis GO:0003091 14 9 0,000 0,06643809 0,1208921 ! postreplication repair GO:0006301 11 9 0,000 0,06643809 0,12079654 ! mRNA cleavage GO:0006379 13 9 0,000 0,06643809 0,12070112 ! hindbrain morphogenesis GO:0021575 12 9 0,000 0,06643809 0,12060585 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,06643809 0,12051074 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 0,06643809 0,12041577 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 0,06643809 0,12032096 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 0,06643809 0,12022629 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 0,000 0,06643809 0,12013177 ! acid secretion GO:0046717 14 9 0,000 0,06643809 0,12003741 ! musculoskeletal movement GO:0050881 11 9 0,000 0,06643809 0,11994318 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 0,06643809 0,11984911 ! methionine biosynthetic process GO:0009086 10 9 0,000 0,06643809 0,11975519 ! purine base metabolic process GO:0006144 18 9 0,000 0,06643809 0,11966141 ! thymus development GO:0048538 15 9 0,000 0,06643809 0,11956778 ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 0,06643809 0,11947429 ! spleen development GO:0048536 15 9 0,000 0,06643809 0,11938095 ! negative regulation of BMP signaling pathway GO:0030514 13 9 0,000 0,06643809 0,11928776 ! regulation of RNA splicing GO:0043484 14 9 0,000 0,06643809 0,11919471 ! detection of calcium ion GO:0005513 13 9 0,000 0,06643809 0,11910181 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,06643809 0,11900905 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 0,000 0,06643809 0,11891643 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 0,06643809 0,11882396 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,06643809 0,11873164 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,06643809 0,11863945 ! positive regulation of amine transport GO:0051954 15 9 0,000 0,06643809 0,11854741 ! prepulse inhibition GO:0060134 14 9 0,000 0,06643809 0,11845552 ! positive regulation of protein polymerization GO:0032273 15 9 0,000 0,06643809 0,11836376 ! insulin secretion GO:0030073 17 9 0,000 0,06643809 0,11827215 ! response to nicotine GO:0035094 16 9 0,000 0,06643809 0,11818068 ! establishment of cell polarity GO:0030010 12 9 0,000 0,06643809 0,11808935 ! carbohydrate transport GO:0008643 74 57 1,000 0,06991947 0,1241813 ! multicellular organism reproduction GO:0032504 83 57 1,000 0,06991947 0,12408548 GO:0048609|reproductive process in a multicellular organism, ! developmental maturation GO:0021700 75 57 1,000 0,06991947 0,12398981 ! regulation of cytokine biosynthetic process GO:0042035 76 58 1,000 0,07206682 0,12769929 ! protein maturation by peptide bond cleavage GO:0051605 76 58 1,000 0,07206682 0,12760099 ! negative regulation of muscle development GO:0048635 12 10 0,000 0,07354413 0,13011653 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,07354413 0,13001652 ! neuron fate specification GO:0048665 11 10 0,000 0,07354413 0,12991666 ! negative regulation of blood pressure GO:0045776 22 10 0,000 0,07354413 0,12981696 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 0,07354413 0,1297174 ! thyroid gland development GO:0030878 19 10 0,000 0,07354413 0,129618 ! regulation of phosphatase activity GO:0010921 21 10 0,000 0,07354413 0,12951876 ! synapsis GO:0007129 13 10 0,000 0,07354413 0,12941966 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 0,07354413 0,12932072 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,07354413 0,12922192 GO:0007520|myoblast fusion, ! hair follicle morphogenesis GO:0031069 17 10 0,000 0,07354413 0,12912328 ! sulfate transport GO:0008272 12 10 0,000 0,07354413 0,12902479 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 0,07354413 0,12892644 GO:0048200|Golgi transport vesicle coating, ! androgen metabolic process GO:0008209 13 10 0,000 0,07354413 0,12882825 ! phospholipid efflux GO:0033700 16 10 0,000 0,07354413 0,12873021 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 0,000 0,07354413 0,12863232 ! positive regulation of heart contraction GO:0045823 14 10 0,000 0,07354413 0,12853457 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 0,07354413 0,12843697 ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 0,07354413 0,12833953 ! pathogenesis GO:0009405 13 10 0,000 0,07354413 0,12824223 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,07354413 0,12814507 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 0,07354413 0,12804807 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 0,07354413 0,12795121 ! melanocyte differentiation GO:0030318 15 10 0,000 0,07354413 0,12785449 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 0,07354413 0,12775793 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 0,07354413 0,12766151 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,07354413 0,12756523 ! B cell proliferation GO:0042100 14 10 0,000 0,07354413 0,1274691 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 0,07354413 0,12737311 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,07354413 0,12727727 ! forebrain cell migration GO:0021885 17 10 0,000 0,07354413 0,12718158 ! lipid digestion GO:0044241 15 10 0,000 0,07354413 0,12708602 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,07354413 0,12699061 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,07354413 0,12689535 ! UV protection GO:0009650 14 10 0,000 0,07354413 0,12680022 ! entry into host cell GO:0030260 20 10 0,000 0,07354413 0,12670524 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 16 10 0,000 0,07354413 0,1266104 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,07354413 0,1265157 ! negative regulation of ossification GO:0030279 19 10 0,000 0,07354413 0,12642115 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 0,07354413 0,12632673 ! alpha-beta T cell activation GO:0046631 16 10 0,000 0,07354413 0,12623246 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 0,07354413 0,12613833 ! regulation of organ growth GO:0046620 11 10 0,000 0,07354413 0,12604433 ! response to dsRNA GO:0043331 18 10 0,000 0,07354413 0,12595048 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 0,07354413 0,12585677 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,07354413 0,12576319 ! regulation of B cell differentiation GO:0045577 16 10 0,000 0,07354413 0,12566976 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,07354413 0,12557646 ! fucose catabolic process GO:0019317 16 10 0,000 0,07354413 0,12548331 GO:0042355|L-fucose catabolic process, ! DNA methylation GO:0006306 15 10 0,000 0,07354413 0,12539029 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 18 10 0,000 0,07354413 0,1252974 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 0,07354413 0,12520466 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,07354413 0,12511205 ! zymogen activation GO:0031638 14 10 0,000 0,07354413 0,12501958 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,07354413 0,12492725 ! glutathione biosynthetic process GO:0006750 11 10 0,000 0,07354413 0,12483505 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 0,07354413 0,12474299 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 0,07354413 0,12465107 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,07354413 0,12455927 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 0,07354413 0,12446762 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 0,07354413 0,1243761 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 0,000 0,07354413 0,12428471 GO:0043470|regulation of carbohydrate catabolic process, ! positive regulation of JNK cascade GO:0046330 14 10 0,000 0,07354413 0,12419346 ! detection of bacterium GO:0016045 10 10 0,000 0,07354413 0,12410234 ! embryonic gut development GO:0048566 11 10 0,000 0,07354413 0,12401136 ! activation of innate immune response GO:0002218 10 10 0,000 0,07354413 0,12392051 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 21 10 0,000 0,07354413 0,12382979 ! cardiac cell differentiation GO:0035051 16 10 0,000 0,07354413 0,12373921 ! developmental induction GO:0031128 13 10 0,000 0,07354413 0,12364875 GO:0045168|cell-cell signaling involved in cell fate specification, ! T cell receptor signaling pathway GO:0050852 18 10 0,000 0,07354413 0,12355843 ! cytoplasmic sequestering of protein GO:0051220 14 10 0,000 0,07354413 0,12346824 ! negative regulation of immune effector process GO:0002698 16 10 0,000 0,07354413 0,12337819 ! actin filament organization GO:0007015 95 59 1,000 0,07423541 0,12444712 ! phosphoinositide metabolic process GO:0030384 87 60 1,000 0,07642481 0,12802408 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 1,000 0,07642481 0,1279309 ! fertilization GO:0009566 68 60 1,000 0,07642481 0,12783786 ! regulation of homeostatic process GO:0032844 105 60 1,000 0,07642481 0,12774496 ! urogenital system development GO:0001655 101 61 1,000 0,07863457 0,13134315 ! rRNA transcription GO:0009303 17 11 0,000 0,08059648 0,13452242 ! respiratory burst GO:0045730 14 11 0,000 0,08059648 0,13442487 ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 0,08059648 0,13432746 ! cortical cytoskeleton organization GO:0030865 20 11 0,000 0,08059648 0,13423019 ! virus-host interaction GO:0019048 17 11 0,000 0,08059648 0,13413307 ! Golgi vesicle budding GO:0048194 17 11 0,000 0,08059648 0,13403608 ! RNA polyadenylation GO:0043631 19 11 0,000 0,08059648 0,13393923 ! detection of mechanical stimulus GO:0050982 15 11 0,000 0,08059648 0,13384252 ! mating GO:0007618 14 11 0,000 0,08059648 0,13374596 ! dopamine receptor signaling pathway GO:0007212 22 11 0,000 0,08059648 0,13364953 ! T cell proliferation GO:0042098 20 11 0,000 0,08059648 0,13355324 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 0,08059648 0,13345709 ! bone resorption GO:0045453 16 11 0,000 0,08059648 0,13336108 ! regulated secretory pathway GO:0045055 14 11 0,000 0,08059648 0,1332652 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 0,08059648 0,13316947 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 0,08059648 0,13307387 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 0,08059648 0,13297841 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 0,08059648 0,13288308 ! syncytium formation GO:0006949 15 11 0,000 0,08059648 0,13278789 ! plasma membrane organization GO:0007009 18 11 0,000 0,08059648 0,13269284 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,08059648 0,13259792 ! mitotic spindle organization GO:0007052 15 11 0,000 0,08059648 0,13250314 ! cellular carbohydrate catabolic process GO:0044275 13 11 0,000 0,08059648 0,1324085 ! regulation of intracellular pH GO:0051453 17 11 0,000 0,08059648 0,13231399 ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 0,08059648 0,13221961 ! adult heart development GO:0007512 11 11 0,000 0,08059648 0,13212537 ! actin cytoskeleton reorganization GO:0031532 21 11 0,000 0,08059648 0,13203127 ! temperature homeostasis GO:0001659 16 11 0,000 0,08059648 0,13193729 ! L-glutamate transport GO:0015813 16 11 0,000 0,08059648 0,13184345 GO:0015800|acidic amino acid transport, ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,08059648 0,13174975 ! protein targeting to peroxisome GO:0006625 20 11 0,000 0,08059648 0,13165618 ! stem cell development GO:0048864 29 11 0,000 0,08059648 0,13156274 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 0,08059648 0,13146943 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 0,08059648 0,13137626 ! regulation of phagocytosis GO:0050764 14 11 0,000 0,08059648 0,13128321 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 0,08059648 0,1311903 ! vasoconstriction GO:0042310 15 11 0,000 0,08059648 0,13109752 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 0,08059648 0,13100487 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,08059648 0,13091236 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 0,08059648 0,13081997 ! regulation of Rho GTPase activity GO:0032319 18 11 0,000 0,08059648 0,13072771 ! ribosome assembly GO:0042255 13 11 0,000 0,08059648 0,13063559 ! nitric oxide metabolic process GO:0046209 14 11 0,000 0,08059648 0,13054359 GO:0006809|nitric oxide biosynthetic process, ! histone deacetylation GO:0016575 13 11 0,000 0,08059648 0,13045172 ! chromatin silencing GO:0006342 19 11 0,000 0,08059648 0,13035998 ! nucleosome positioning GO:0016584 13 11 0,000 0,08059648 0,13026837 ! T cell homeostasis GO:0043029 20 11 0,000 0,08059648 0,13017689 ! regulation of isotype switching GO:0045191 19 11 0,000 0,08059648 0,13008554 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 0,08059648 0,12999432 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,08059648 0,12990322 ! aromatic amino acid family catabolic process GO:0009074 13 11 0,000 0,08059648 0,12981225 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 0,08059648 0,12972141 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,08059648 0,1296307 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 0,08059648 0,12954011 ! male genitalia development GO:0030539 13 11 0,000 0,08059648 0,12944965 ! cholesterol efflux GO:0033344 19 11 0,000 0,08059648 0,12935931 ! digestive tract morphogenesis GO:0048546 15 11 0,000 0,08059648 0,12926911 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 21 11 0,000 0,08059648 0,12917902 ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 0,08059648 0,12908906 ! germ cell migration GO:0008354 18 11 0,000 0,08059648 0,12899923 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,08059648 0,12890952 ! defense response to fungus GO:0050832 12 11 0,000 0,08059648 0,12881994 ! mRNA 3'-end processing GO:0031124 19 11 0,000 0,08059648 0,12873048 ! lysogeny GO:0030069 18 11 0,000 0,08059648 0,12864115 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 0,08059648 0,12855194 ! acrosome reaction GO:0007340 13 11 0,000 0,08059648 0,12846285 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 0,08059648 0,12837389 ! hexose catabolic process GO:0019320 82 64 1,000 0,08538178 0,1359018 ! adaptive immune response GO:0002250 94 64 1,000 0,08538178 0,13580781 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! lactation GO:0007595 20 12 0,000 0,08759554 0,13923272 ! reproductive cellular process GO:0048610 14 12 0,000 0,08759554 0,13913657 ! tRNA modification GO:0006400 14 12 0,000 0,08759554 0,13904054 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 0,08759554 0,13894465 ! positive regulation of blood pressure GO:0045777 16 12 0,000 0,08759554 0,1388489 ! positive regulation of cellular catabolic process GO:0031331 22 12 0,000 0,08759554 0,13875327 ! 'de novo' protein folding GO:0006458 18 12 0,000 0,08759554 0,13865777 ! dicarboxylic acid transport GO:0006835 22 12 0,000 0,08759554 0,13856241 ! non-recombinational repair GO:0000726 19 12 0,000 0,08759554 0,13846718 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 0,08759554 0,13837208 ! peroxisomal transport GO:0043574 21 12 0,000 0,08759554 0,13827711 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 0,08759554 0,13818227 ! cytokine biosynthetic process GO:0042089 16 12 0,000 0,08759554 0,13808756 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,08759554 0,13799298 ! heart looping GO:0001947 15 12 0,000 0,08759554 0,13789853 ! palate development GO:0060021 15 12 0,000 0,08759554 0,1378042 ! positive regulation of cell growth GO:0030307 16 12 0,000 0,08759554 0,13771001 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 0,08759554 0,13761595 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,08759554 0,13752201 ! arginine metabolic process GO:0006525 13 12 0,000 0,08759554 0,1374282 ! methionine metabolic process GO:0006555 13 12 0,000 0,08759554 0,13733452 ! tyrosine metabolic process GO:0006570 14 12 0,000 0,08759554 0,13724097 ! Golgi organization GO:0007030 18 12 0,000 0,08759554 0,13714755 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 0,08759554 0,13705425 ! monoamine transport GO:0015844 13 12 0,000 0,08759554 0,13696108 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,08759554 0,13686803 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 0,000 0,08759554 0,13677512 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! neutral amino acid transport GO:0015804 19 12 0,000 0,08759554 0,13668232 ! L-amino acid transport GO:0015807 20 12 0,000 0,08759554 0,13658966 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 0,08759554 0,13649712 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,08759554 0,1364047 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 0,08759554 0,13631241 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,08759554 0,13622025 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 0,08759554 0,13612821 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 0,08759554 0,13603629 ! cerebellum development GO:0021549 13 12 0,000 0,08759554 0,1359445 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,08759554 0,13585283 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,08759554 0,13576128 ! histone methylation GO:0016571 15 12 0,000 0,08759554 0,13566986 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 0,08759554 0,13557856 ! negative regulation of protein secretion GO:0050709 20 12 0,000 0,08759554 0,13548739 ! regulation of epidermis development GO:0045682 17 12 0,000 0,08759554 0,13539634 ! intestinal absorption GO:0050892 19 12 0,000 0,08759554 0,1353054 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 0,08759554 0,1352146 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,08759554 0,13512391 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 0,08759554 0,13503334 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,08759554 0,1349429 ! RNA 3'-end processing GO:0031123 20 12 0,000 0,08759554 0,13485257 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 0,08759554 0,13476237 ! response to cold GO:0009409 14 12 0,000 0,08759554 0,13467229 ! regulation of caspase activity GO:0043281 97 65 1,000 0,08766875 0,13469481 ! defense response to bacterium GO:0042742 73 65 1,000 0,08766875 0,1346049 ! regulation of MAPKKK cascade GO:0043408 101 65 1,000 0,08766875 0,1345151 ! positive regulation of T cell activation GO:0050870 94 65 1,000 0,08766875 0,13442542 ! protein oligomerization GO:0051259 100 65 1,000 0,08766875 0,13433587 ! regulation of immune effector process GO:0002697 101 66 1,000 0,08997399 0,13777642 ! regulation of endopeptidase activity GO:0052548 99 67 1,000 0,09229709 0,14123972 ! regulation of neuron differentiation GO:0045664 107 67 1,000 0,09229709 0,14114581 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,09454172 0,14448237 ! cGMP metabolic process GO:0046068 16 13 0,000 0,09454172 0,14438643 GO:0006182|cGMP biosynthetic process, ! water transport GO:0006833 17 13 0,000 0,09454172 0,14429062 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,09454172 0,14419494 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,09454172 0,14409938 ! lipid localization GO:0010876 24 13 0,000 0,09454172 0,14400395 GO:0019915|lipid storage, ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,09454172 0,14390865 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,09454172 0,14381347 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! cell differentiation in spinal cord GO:0021515 16 13 0,000 0,09454172 0,14371842 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,09454172 0,14362349 ! response to hexose stimulus GO:0009746 19 13 0,000 0,09454172 0,14352869 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! induction of apoptosis via death domain receptors GO:0008625 15 13 0,000 0,09454172 0,14343401 ! glutamate metabolic process GO:0006536 18 13 0,000 0,09454172 0,14333946 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,09454172 0,14324504 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,09454172 0,14315073 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 0,09454172 0,14305656 ! NAD metabolic process GO:0019674 21 13 0,000 0,09454172 0,1429625 ! negative regulation of mitotic cell cycle GO:0045930 23 13 0,000 0,09454172 0,14286857 ! bone mineralization GO:0030282 15 13 0,000 0,09454172 0,14277476 ! regulation of exocytosis GO:0017157 17 13 0,000 0,09454172 0,14268108 ! intermediate filament cytoskeleton organization GO:0045104 23 13 0,000 0,09454172 0,14258752 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 0,09454172 0,14249408 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,09454172 0,14240076 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 0,09454172 0,14230757 ! negative regulation of protein import into nucleus GO:0042308 25 13 0,000 0,09454172 0,1422145 ! positive regulation of protein import into nucleus GO:0042307 23 13 0,000 0,09454172 0,14212155 ! genitalia development GO:0048806 15 13 0,000 0,09454172 0,14202872 ! regulation of cellular pH GO:0030641 20 13 0,000 0,09454172 0,14193601 ! cellular pigmentation GO:0033059 24 13 0,000 0,09454172 0,14184342 ! tissue regeneration GO:0042246 21 13 0,000 0,09454172 0,14175095 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 0,09454172 0,14165861 ! cofactor transport GO:0051181 19 13 0,000 0,09454172 0,14156638 ! NADP metabolic process GO:0006739 18 13 0,000 0,09454172 0,14147428 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,09454172 0,14138229 ! gas transport GO:0015669 18 13 0,000 0,09454172 0,14129043 ! heme biosynthetic process GO:0006783 20 13 0,000 0,09454172 0,14119868 ! regulation of axon extension GO:0030516 23 13 0,000 0,09454172 0,14110705 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 0,000 0,09454172 0,14101554 ! lymphocyte homeostasis GO:0002260 24 13 0,000 0,09454172 0,14092415 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,09454172 0,14083288 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,09454172 0,14074172 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,09454172 0,14065069 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,09454172 0,14055977 ! acute inflammatory response GO:0002526 92 68 1,000 0,09463764 0,14061148 ! learning or memory GO:0007611 123 68 1,000 0,09463764 0,14052071 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 1,000 0,09936955 0,14745159 ! humoral immune response GO:0006959 86 70 1,000 0,09936955 0,14735653 ! amine transport GO:0015837 101 70 1,000 0,09936955 0,14726158 ! regulation of catabolic process GO:0009894 106 70 1,000 0,09936955 0,14716676 ! G1 phase of mitotic cell cycle GO:0000080 23 14 0,000 0,10143542 0,15012964 ! superoxide anion generation GO:0042554 18 14 0,000 0,10143542 0,15003309 ! neuron maturation GO:0042551 21 14 0,000 0,10143542 0,14993667 ! regulation of lipid biosynthetic process GO:0046890 16 14 0,000 0,10143542 0,14984037 ! myotube differentiation GO:0014902 21 14 0,000 0,10143542 0,1497442 ! heterophilic cell adhesion GO:0007157 29 14 0,000 0,10143542 0,14964815 ! inositol metabolic process GO:0006020 20 14 0,000 0,10143542 0,14955222 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,10143542 0,14945641 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,10143542 0,14936073 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,10143542 0,14926517 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,10143542 0,14916973 ! gene silencing by RNA GO:0031047 20 14 0,000 0,10143542 0,14907442 ! response to cAMP GO:0051591 19 14 0,000 0,10143542 0,14897922 ! startle response GO:0001964 21 14 0,000 0,10143542 0,14888415 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 0,000 0,10143542 0,1487892 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 0,10143542 0,14869437 ! activation of MAPKK activity GO:0000186 21 14 0,000 0,10143542 0,14859966 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,10143542 0,14850507 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 0,10143542 0,1484106 ! epidermis morphogenesis GO:0048730 29 14 0,000 0,10143542 0,14831625 ! glycine metabolic process GO:0006544 22 14 0,000 0,10143542 0,14822202 ! pituitary gland development GO:0021983 23 14 0,000 0,10143542 0,14812791 ! cellular response to starvation GO:0009267 21 14 0,000 0,10143542 0,14803392 ! negative regulation of microtubule depolymerization GO:0007026 31 14 0,000 0,10143542 0,14794005 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 20 14 0,000 0,10143542 0,1478463 ! regulation of heart rate GO:0002027 23 14 0,000 0,10143542 0,14775267 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,10143542 0,14765915 ! negative regulation of caspase activity GO:0043154 20 14 0,000 0,10143542 0,14756576 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 0,000 0,10143542 0,14747248 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 27 14 0,000 0,10143542 0,14737932 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 0,000 0,10143542 0,14728628 ! G1/S transition checkpoint GO:0031575 33 14 0,000 0,10143542 0,14719335 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 0,10143542 0,14710054 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 24 14 0,000 0,10143542 0,14700785 ! axon cargo transport GO:0008088 27 14 0,000 0,10143542 0,14691528 ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,10143542 0,14682282 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 0,10143542 0,14673048 ! T cell differentiation in the thymus GO:0033077 27 14 0,000 0,10143542 0,14663825 ! mRNA splice site selection GO:0006376 26 14 0,000 0,10143542 0,14654614 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,10143542 0,14645415 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 0,10143542 0,14636227 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,10143542 0,14627051 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 0,10143542 0,14617886 ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 0,10143542 0,14608733 ! regulation of erythrocyte differentiation GO:0045646 27 14 0,000 0,10143542 0,14599591 ! muscle maintenance GO:0046716 19 14 0,000 0,10143542 0,1459046 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 0,10143542 0,14581341 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 0,10143542 0,14572234 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,10143542 0,14563137 ! cell killing GO:0001906 20 14 0,000 0,10143542 0,14554053 ! release of cytochrome c from mitochondria GO:0001836 23 14 0,000 0,10143542 0,14544979 ! cilium assembly GO:0042384 20 14 0,000 0,10143542 0,14535917 ! leukocyte mediated immunity GO:0002443 99 71 1,000 0,10176013 0,14573369 ! steroid biosynthetic process GO:0006694 94 71 1,000 0,10176013 0,145643 ! monosaccharide catabolic process GO:0046365 91 71 1,000 0,10176013 0,14555243 ! regulation of peptidase activity GO:0052547 106 72 1,000 0,10416662 0,14890194 ! negative regulation of organelle organization GO:0010639 115 72 1,000 0,10416662 0,14880946 ! mitochondrion organization GO:0007005 104 73 1,000 0,10658864 0,15217497 ! regulation of protein ubiquitination GO:0031396 19 15 0,000 0,10827702 0,15448954 ! positive regulation of cell size GO:0045793 20 15 0,000 0,10827702 0,15439377 ! metencephalon development GO:0022037 19 15 0,000 0,10827702 0,15429811 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,10827702 0,15420257 ! skin development GO:0043588 25 15 0,000 0,10827702 0,15410714 ! embryonic hindlimb morphogenesis GO:0035116 25 15 0,000 0,10827702 0,15401184 ! embryonic forelimb morphogenesis GO:0035115 17 15 0,000 0,10827702 0,15391665 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 0,10827702 0,15382158 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,10827702 0,15372663 ! bile acid metabolic process GO:0008206 22 15 0,000 0,10827702 0,1536318 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 0,10827702 0,15353708 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 0,10827702 0,15344248 ! adult walking behavior GO:0007628 25 15 0,000 0,10827702 0,153348 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,10827702 0,15325363 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,10827702 0,15315938 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,10827702 0,15306524 ! regulation of survival gene product expression GO:0045884 20 15 0,000 0,10827702 0,15297122 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,10827702 0,15287731 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 0,10827702 0,15278352 ! cerebral cortex development GO:0021987 29 15 0,000 0,10827702 0,15268985 ! response to osmotic stress GO:0006970 22 15 0,000 0,10827702 0,15259629 ! vesicle coating GO:0006901 25 15 0,000 0,10827702 0,15250284 ! DNA integration GO:0015074 22 15 0,000 0,10827702 0,15240951 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,10827702 0,1523163 ! regulation of vasodilation GO:0042312 24 15 0,000 0,10827702 0,15222319 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 0,10827702 0,1521302 ! neuron recognition GO:0008038 22 15 0,000 0,10827702 0,15203733 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,10827702 0,15194457 ! positive regulation of oxidoreductase activity GO:0051353 21 15 0,000 0,10827702 0,15185192 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,10827702 0,15175938 ! biomineral formation GO:0031214 18 15 0,000 0,10827702 0,15166696 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,10827702 0,15157465 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,10827702 0,15148245 ! dopamine metabolic process GO:0042417 30 15 0,000 0,10827702 0,15139036 ! organic cation transport GO:0015695 19 15 0,000 0,10827702 0,15129839 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,10827702 0,15120652 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 21 15 0,000 0,10827702 0,15111477 ! positive regulation of neuron apoptosis GO:0043525 29 15 0,000 0,10827702 0,15102313 ! peptide hormone processing GO:0016486 19 15 0,000 0,10827702 0,1509316 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 0,000 0,10827702 0,15084018 ! protein import into nucleus GO:0006606 118 74 1,000 0,10902582 0,15179139 ! nuclear import GO:0051170 121 75 1,000 0,11147779 0,15511127 ! regulation of cell morphogenesis GO:0022604 140 76 1,000 0,1139442 0,15844719 ! protein secretion GO:0009306 27 16 0,000 0,11506692 0,15991173 ! regulation of glucose metabolic process GO:0010906 22 16 0,000 0,11506692 0,15981516 ! bone remodeling GO:0046849 24 16 0,000 0,11506692 0,15971872 ! endothelial cell migration GO:0043542 22 16 0,000 0,11506692 0,15962238 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,11506692 0,15952617 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,11506692 0,15943007 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,11506692 0,15933408 ! glial cell development GO:0021782 24 16 0,000 0,11506692 0,15923821 ! patterning of blood vessels GO:0001569 24 16 0,000 0,11506692 0,15914246 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,11506692 0,15904682 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,11506692 0,1589513 ! protein polyubiquitination GO:0000209 26 16 0,000 0,11506692 0,15885589 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,11506692 0,15876059 ! cellular response to unfolded protein GO:0034620 19 16 0,000 0,11506692 0,15866541 GO:0030968|endoplasmic reticulum unfolded protein response, ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 0,11506692 0,15857035 ! fructose metabolic process GO:0006000 20 16 0,000 0,11506692 0,1584754 ! regulation of protein binding GO:0043393 27 16 0,000 0,11506692 0,15838056 ! regulation of dephosphorylation GO:0035303 33 16 0,000 0,11506692 0,15828583 ! protein export from nucleus GO:0006611 24 16 0,000 0,11506692 0,15819122 ! negative regulation of immune response GO:0050777 28 16 0,000 0,11506692 0,15809672 ! DNA replication initiation GO:0006270 25 16 0,000 0,11506692 0,15800234 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,11506692 0,15790806 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,11506692 0,1578139 ! diencephalon development GO:0021536 25 16 0,000 0,11506692 0,15771985 ! neural crest cell migration GO:0001755 24 16 0,000 0,11506692 0,15762591 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,11506692 0,15753209 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 0,11506692 0,15743838 ! steroid catabolic process GO:0006706 22 16 0,000 0,11506692 0,15734477 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,11506692 0,15725128 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 0,000 0,11506692 0,1571579 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 0,000 0,11506692 0,15706464 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,11506692 0,15697148 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,11506692 0,15687843 ! sperm-egg recognition GO:0035036 16 16 0,000 0,11506692 0,15678549 GO:0007339|binding of sperm to zona pellucida, ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 0,11506692 0,15669266 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 0,000 0,11506692 0,15659995 ! inner ear receptor cell differentiation GO:0060113 30 16 0,000 0,11506692 0,15650734 ! negative regulation of translation GO:0017148 22 16 0,000 0,11506692 0,15641484 ! cholesterol metabolic process GO:0008203 109 77 1,000 0,11642468 0,15816702 ! cellular respiration GO:0045333 107 79 1,000 0,12142647 0,16486474 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,1218055 0,1652818 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,1218055 0,16518435 ! negative regulation of defense response GO:0031348 19 17 0,000 0,1218055 0,16508701 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 0,1218055 0,16498978 ! glycerol metabolic process GO:0006071 20 17 0,000 0,1218055 0,16489267 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,1218055 0,16479568 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,1218055 0,1646988 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,1218055 0,16460203 ! signal complex assembly GO:0007172 29 17 0,000 0,1218055 0,16450537 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,1218055 0,16440883 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,1218055 0,16431241 ! forelimb morphogenesis GO:0035136 19 17 0,000 0,1218055 0,16421609 ! memory GO:0007613 25 17 0,000 0,1218055 0,16411989 ! keratinization GO:0031424 17 17 0,000 0,1218055 0,1640238 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,1218055 0,16392783 ! negative regulation of peptidase activity GO:0010466 23 17 0,000 0,1218055 0,16383196 ! retinoid metabolic process GO:0001523 22 17 0,000 0,1218055 0,16373621 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 24 17 0,000 0,1218055 0,16364057 ! vacuolar transport GO:0007034 24 17 0,000 0,1218055 0,16354504 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,1218055 0,16344962 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,1218055 0,16335432 ! membrane budding GO:0006900 29 17 0,000 0,1218055 0,16325912 ! heme metabolic process GO:0042168 27 17 0,000 0,1218055 0,16316404 ! negative regulation of protein catabolic process GO:0042177 26 17 0,000 0,1218055 0,16306906 ! body fluid secretion GO:0007589 27 17 0,000 0,1218055 0,1629742 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,1218055 0,16287945 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,1218055 0,16278481 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,1218055 0,16269027 ! sensory perception of pain GO:0019233 23 17 0,000 0,1218055 0,16259585 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,1218055 0,16250154 GO:0002712|regulation of B cell mediated immunity, ! long-chain fatty acid transport GO:0015909 24 17 0,000 0,1218055 0,16240734 ! synaptogenesis GO:0007416 24 17 0,000 0,1218055 0,16231324 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,1218055 0,16221925 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,1218055 0,16212538 ! proximal/distal pattern formation GO:0009954 25 17 0,000 0,1218055 0,16203161 ! aromatic compound catabolic process GO:0019439 22 17 0,000 0,1218055 0,16193795 ! negative regulation of coagulation GO:0050819 23 17 0,000 0,1218055 0,1618444 ! alcohol catabolic process GO:0046164 104 80 1,000 0,12394708 0,16459485 ! protein localization in nucleus GO:0034504 133 80 1,000 0,12394708 0,16449987 ! forebrain development GO:0030900 131 80 1,000 0,12394708 0,164405 ! positive regulation of DNA replication GO:0045740 29 18 0,000 0,12849315 0,17033675 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 0,000 0,12849315 0,17023863 ! positive regulation of angiogenesis GO:0045766 35 18 0,000 0,12849315 0,17014062 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 0,12849315 0,17004273 ! cAMP metabolic process GO:0046058 33 18 0,000 0,12849315 0,16994494 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,12849315 0,16984727 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,12849315 0,16974972 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 0,12849315 0,16965227 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,12849315 0,16955494 GO:0050886|endocrine process, ! mechanoreceptor differentiation GO:0042490 32 18 0,000 0,12849315 0,16945772 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,12849315 0,16936061 ! glutamine metabolic process GO:0006541 23 18 0,000 0,12849315 0,16926361 ! pigmentation during development GO:0048066 31 18 0,000 0,12849315 0,16916672 ! central nervous system neuron development GO:0021954 30 18 0,000 0,12849315 0,16906994 ! positive regulation of cytoskeleton organization GO:0051495 33 18 0,000 0,12849315 0,16897327 ! fucose metabolic process GO:0006004 26 18 0,000 0,12849315 0,16887672 ! response to fungus GO:0009620 19 18 0,000 0,12849315 0,16878027 ! peptide cross-linking GO:0018149 31 18 0,000 0,12849315 0,16868394 ! heart process GO:0003015 27 18 0,000 0,12849315 0,16858771 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,12849315 0,16849159 GO:0006692|prostanoid metabolic process, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,12849315 0,16839559 ! visual learning GO:0008542 35 18 0,000 0,12849315 0,16829969 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,12849315 0,1682039 ! detection of chemical stimulus GO:0009593 26 18 0,000 0,12849315 0,16810822 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,12849315 0,16801265 ! cellular response to nutrient levels GO:0031669 27 18 0,000 0,12849315 0,16791719 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,12849315 0,16782184 ! vitamin transport GO:0051180 24 18 0,000 0,12849315 0,16772659 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,12849315 0,16763146 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,12849315 0,16753643 ! cell-cell recognition GO:0009988 20 18 0,000 0,12849315 0,1674415 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,12849315 0,16734669 ! estrogen receptor signaling pathway GO:0030520 30 18 0,000 0,12849315 0,16725198 ! gut development GO:0048565 26 18 0,000 0,12849315 0,16715738 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 0,000 0,12849315 0,16706289 ! sterol metabolic process GO:0016125 120 84 1,000 0,1341531 0,17432324 ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,13513026 0,17549384 ! positive regulation of ossification GO:0045778 30 19 0,000 0,13513026 0,17539481 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,13513026 0,17529588 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 0,000 0,13513026 0,17519707 ! regulation of carbohydrate metabolic process GO:0006109 28 19 0,000 0,13513026 0,17509837 GO:0010675|regulation of cellular carbohydrate metabolic process, ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,13513026 0,17499977 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,13513026 0,17490129 ! regeneration GO:0031099 32 19 0,000 0,13513026 0,17480292 ! response to alkaloid GO:0043279 32 19 0,000 0,13513026 0,17470466 ! sensory perception of taste GO:0050909 23 19 0,000 0,13513026 0,17460652 ! smooth muscle contraction GO:0006939 36 19 0,000 0,13513026 0,17450848 ! peroxisome organization GO:0007031 29 19 0,000 0,13513026 0,17441055 ! digestive system process GO:0022600 30 19 0,000 0,13513026 0,17431273 ! cellular response to reactive oxygen species GO:0034614 27 19 0,000 0,13513026 0,17421502 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,13513026 0,17411742 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,13513026 0,17401993 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,13513026 0,17392255 ! response to starvation GO:0042594 30 19 0,000 0,13513026 0,17382528 ! response to lipopolysaccharide GO:0032496 26 19 0,000 0,13513026 0,17372812 ! cytolysis GO:0019835 20 19 0,000 0,13513026 0,17363106 ! renal system process GO:0003014 35 19 0,000 0,13513026 0,17353411 ! vasodilation GO:0042311 33 19 0,000 0,13513026 0,17343728 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,13513026 0,17334055 ! regulation of fatty acid metabolic process GO:0019217 28 19 0,000 0,13513026 0,17324392 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,13513026 0,17314741 ! sarcomere organization GO:0045214 23 19 0,000 0,13513026 0,173051 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,13513026 0,1729547 ! aromatic amino acid family metabolic process GO:0009072 24 19 0,000 0,13513026 0,17285851 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,13513026 0,17276242 GO:0043450|alkene biosynthetic process, ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 0,13513026 0,17266644 ! embryonic organ morphogenesis GO:0048562 23 19 0,000 0,13513026 0,17257057 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 0,13513026 0,17247481 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 0,000 0,13513026 0,17237915 ! protein stabilization GO:0050821 26 19 0,000 0,13513026 0,17228359 ! rRNA metabolic process GO:0016072 107 85 1,000 0,13673386 0,17423151 GO:0006364|rRNA processing, ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,1417172 0,18048148 ! iron ion transport GO:0006826 37 20 0,000 0,1417172 0,1803816 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,1417172 0,18028183 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,1417172 0,18018217 GO:0006044|N-acetylglucosamine metabolic process, ! microtubule-based transport GO:0010970 37 20 0,000 0,1417172 0,18008263 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,1417172 0,17998319 ! hindlimb morphogenesis GO:0035137 32 20 0,000 0,1417172 0,17988386 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,1417172 0,17978464 ! spinal cord development GO:0021510 31 20 0,000 0,1417172 0,17968553 ! response to ethanol GO:0045471 37 20 0,000 0,1417172 0,17958653 ! multicellular organismal response to stress GO:0033555 32 20 0,000 0,1417172 0,17948764 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,1417172 0,17938886 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,1417172 0,17929018 ! chromosome condensation GO:0030261 31 20 0,000 0,1417172 0,17919162 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,1417172 0,17909316 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,1417172 0,17899481 ! regulation of ARF GTPase activity GO:0032312 31 20 0,000 0,1417172 0,17889657 ! DNA modification GO:0006304 28 20 0,000 0,1417172 0,17879844 ! collagen fibril organization GO:0030199 45 20 0,000 0,1417172 0,17870041 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,1417172 0,17860249 ! collagen catabolic process GO:0030574 25 20 0,000 0,1417172 0,17850468 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,1417172 0,17840698 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 0,1417172 0,17830938 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,1417172 0,17821189 ! alditol metabolic process GO:0019400 24 20 0,000 0,1417172 0,17811451 ! actin filament-based movement GO:0030048 34 20 0,000 0,1417172 0,17801723 ! female pregnancy GO:0007565 130 87 1,000 0,14192824 0,17818502 ! anatomical structure homeostasis GO:0060249 136 88 1,000 0,14454124 0,18136653 ! protein processing GO:0016485 114 88 1,000 0,14454124 0,18126764 ! regulation of neurogenesis GO:0050767 153 89 1,000 0,14716437 0,1844567 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 0,000 0,14825434 0,18572167 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 0,000 0,14825434 0,18562057 GO:0016444|somatic cell DNA recombination, ! regulation of cell killing GO:0031341 34 21 0,000 0,14825434 0,18551958 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,14825434 0,1854187 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,14825434 0,18531793 GO:0009799|determination of symmetry, ! gluconeogenesis GO:0006094 25 21 0,000 0,14825434 0,18521727 ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,14825434 0,18511671 GO:0034105|positive regulation of tissue remodeling, ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,14825434 0,18501627 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,14825434 0,18491594 ! vesicle docking GO:0048278 27 21 0,000 0,14825434 0,18481571 ! phototransduction GO:0007602 25 21 0,000 0,14825434 0,18471559 ! dendrite development GO:0016358 35 21 0,000 0,14825434 0,18461558 ! visual behavior GO:0007632 39 21 0,000 0,14825434 0,18451568 ! ovarian follicle development GO:0001541 30 21 0,000 0,14825434 0,18441589 ! activation of pro-apoptotic gene products GO:0008633 36 21 0,000 0,14825434 0,18431621 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,14825434 0,18421663 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,14825434 0,18411716 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,14825434 0,1840178 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 0,000 0,14825434 0,18391855 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 0,14825434 0,1838194 GO:0060415|muscle tissue morphogenesis, ! leukotriene metabolic process GO:0006691 28 21 0,000 0,14825434 0,18372036 ! regulation of vasoconstriction GO:0019229 31 21 0,000 0,14825434 0,18362142 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,14825434 0,1835226 ! fatty acid transport GO:0015908 30 21 0,000 0,14825434 0,18342388 ! immunoglobulin production GO:0002377 33 21 0,000 0,14825434 0,18332526 GO:0002440|production of molecular mediator of immune response, ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 0,000 0,14825434 0,18322675 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,14825434 0,18312835 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,14825434 0,18303005 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,14825434 0,18293186 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,14825434 0,18283377 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,14825434 0,18273579 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,14825434 0,18263791 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,14825434 0,18254014 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,14825434 0,18244247 ! regulation of multi-organism process GO:0043900 32 21 0,000 0,14825434 0,18234491 ! response to virus GO:0009615 122 91 1,000 0,15243981 0,1873926 ! protein import into nucleus, translocation GO:0000060 36 22 0,000 0,15474207 0,19012113 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 0,000 0,15474207 0,19001962 ! viral genome replication GO:0019079 29 22 0,000 0,15474207 0,18991822 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,15474207 0,18981694 ! spliceosomal snRNP biogenesis GO:0000387 28 22 0,000 0,15474207 0,18971575 ! leukocyte adhesion GO:0007159 38 22 0,000 0,15474207 0,18961468 ! molting cycle process GO:0022404 40 22 0,000 0,15474207 0,18951371 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! dicarboxylic acid metabolic process GO:0043648 33 22 0,000 0,15474207 0,18941285 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,15474207 0,1893121 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 0,000 0,15474207 0,18921146 ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 0,000 0,15474207 0,18911092 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of smooth muscle contraction GO:0006940 36 22 0,000 0,15474207 0,18901049 ! lysosome organization GO:0007040 37 22 0,000 0,15474207 0,18891017 ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,15474207 0,18880995 GO:0051693|actin filament capping, ! ureteric bud development GO:0001657 32 22 0,000 0,15474207 0,18870984 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,15474207 0,18860983 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,15474207 0,18850993 ! membrane depolarization GO:0051899 35 22 0,000 0,15474207 0,18841014 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,15474207 0,18831045 ! regulation of blood coagulation GO:0030193 34 22 0,000 0,15474207 0,18821087 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,15474207 0,18811139 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,15474207 0,18801202 ! neural tube closure GO:0001843 33 22 0,000 0,15474207 0,18791275 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,15474207 0,18781359 ! protein tetramerization GO:0051262 39 22 0,000 0,15474207 0,18771453 ! glycerophospholipid metabolic process GO:0006650 130 92 1,000 0,15509152 0,18803928 ! cell fate commitment GO:0045165 141 92 1,000 0,15509152 0,1879402 ! polysaccharide metabolic process GO:0005976 129 93 1,000 0,15775219 0,19106373 ! carbohydrate catabolic process GO:0016052 121 93 1,000 0,15775219 0,19096317 ! neuron fate commitment GO:0048663 32 23 0,000 0,16118074 0,19501089 ! regulation of transcription factor import into nucleus GO:0042990 46 23 0,000 0,16118074 0,19490837 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 0,000 0,16118074 0,19480594 ! regulation of viral reproduction GO:0050792 32 23 0,000 0,16118074 0,19470363 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,16118074 0,19460142 ! interaction with host GO:0051701 37 23 0,000 0,16118074 0,19449932 ! lymphocyte proliferation GO:0046651 36 23 0,000 0,16118074 0,19439733 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,16118074 0,19429545 ! cellular response to oxidative stress GO:0034599 33 23 0,000 0,16118074 0,19419367 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,16118074 0,194092 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,16118074 0,19399043 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,16118074 0,19388897 ! cell fate determination GO:0001709 45 23 0,000 0,16118074 0,19378762 ! pentose metabolic process GO:0019321 31 23 0,000 0,16118074 0,19368637 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,16118074 0,19358523 ! spermatid development GO:0007286 33 23 0,000 0,16118074 0,19348419 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,16118074 0,19338326 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,16118074 0,19328244 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,16118074 0,19318172 ! somatic diversification of immune receptors GO:0002200 35 23 0,000 0,16118074 0,1930811 ! telomere organization GO:0032200 32 23 0,000 0,16118074 0,19298059 GO:0000723|telomere maintenance, ! negative regulation of catabolic process GO:0009895 34 23 0,000 0,16118074 0,19288018 ! regulation of amine transport GO:0051952 38 23 0,000 0,16118074 0,19277988 ! liver development GO:0001889 40 23 0,000 0,16118074 0,19267968 ! carboxylic acid transport GO:0046942 147 95 1,000 0,1630992 0,19487178 GO:0015849|organic acid transport, ! protein maturation GO:0051604 129 96 1,000 0,165785 0,19797793 ! regulation of cellular catabolic process GO:0031329 36 24 0,000 0,16757074 0,20000659 ! initiation of viral infection GO:0019059 42 24 0,000 0,16757074 0,19990286 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,16757074 0,19979922 ! pyruvate metabolic process GO:0006090 29 24 0,000 0,16757074 0,1996957 ! superoxide metabolic process GO:0006801 32 24 0,000 0,16757074 0,19959229 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,16757074 0,19948898 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,16757074 0,19938578 ! sperm motility GO:0030317 27 24 0,000 0,16757074 0,19928268 ! mitochondrial membrane organization GO:0007006 39 24 0,000 0,16757074 0,19917969 ! vacuole organization GO:0007033 39 24 0,000 0,16757074 0,19907681 ! receptor metabolic process GO:0043112 37 24 0,000 0,16757074 0,19897403 ! neural crest cell development GO:0014032 39 24 0,000 0,16757074 0,19887136 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 38 24 0,000 0,16757074 0,1987688 ! primary neural tube formation GO:0014020 35 24 0,000 0,16757074 0,19866634 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,16757074 0,19856399 GO:0002708|positive regulation of lymphocyte mediated immunity, ! glutathione metabolic process GO:0006749 29 24 0,000 0,16757074 0,19846174 ! neurotransmitter secretion GO:0007269 32 24 0,000 0,16757074 0,1983596 ! regulation of JUN kinase activity GO:0043506 34 24 0,000 0,16757074 0,19825756 ! extracellular structure organization GO:0043062 156 99 1,000 0,17388822 0,20562618 ! protein import GO:0017038 156 99 1,000 0,17388822 0,20552051 ! negative regulation of actin filament depolymerization GO:0030835 36 25 0,000 0,17391242 0,20544354 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,17391242 0,20533808 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,17391242 0,20523272 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,17391242 0,20512747 GO:0006479|protein amino acid methylation, ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,17391242 0,20502233 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,17391242 0,2049173 ! regulation of cellular ketone metabolic process GO:0010565 34 25 0,000 0,17391242 0,20481238 ! male gonad development GO:0008584 33 25 0,000 0,17391242 0,20470756 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,17391242 0,20460285 ! phospholipid transport GO:0015914 35 25 0,000 0,17391242 0,20449825 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,17391242 0,20439375 ! detection of light stimulus GO:0009583 30 25 0,000 0,17391242 0,20428936 ! peptidyl-tyrosine modification GO:0018212 37 25 0,000 0,17391242 0,20418508 ! leukocyte proliferation GO:0070661 39 25 0,000 0,17391242 0,20408091 GO:0032943|mononuclear cell proliferation, ! regulation of translation GO:0006417 151 100 1,000 0,17660369 0,20713334 ! protein localization in organelle GO:0033365 161 100 1,000 0,17660369 0,20702777 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,18020615 0,21114323 ! translational initiation GO:0006413 43 26 0,000 0,18020615 0,21103572 ! regulation of pH GO:0006885 36 26 0,000 0,18020615 0,21092832 ! circadian rhythm GO:0007623 42 26 0,000 0,18020615 0,21082103 ! post-embryonic development GO:0009791 42 26 0,000 0,18020615 0,21071386 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,18020615 0,21060679 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,18020615 0,21049982 ! negative regulation of protein kinase cascade GO:0010741 51 26 0,000 0,18020615 0,21039297 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 0,000 0,18020615 0,21028623 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,18020615 0,21017959 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,18020615 0,21007306 ! negative regulation of protein polymerization GO:0032272 38 26 0,000 0,18020615 0,20996664 ! regulation of coagulation GO:0050818 39 26 0,000 0,18020615 0,20986033 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,18645229 0,21702443 ! regulation of actin filament depolymerization GO:0030834 39 27 0,000 0,18645229 0,21691465 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,18645229 0,21680499 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,18645229 0,21669544 ! membrane docking GO:0022406 39 27 0,000 0,18645229 0,216586 ! inner ear morphogenesis GO:0042472 35 27 0,000 0,18645229 0,21647666 ! catechol metabolic process GO:0009712 43 27 0,000 0,18645229 0,21636744 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,18645229 0,21625833 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,18645229 0,21614933 ! myofibril assembly GO:0030239 36 27 0,000 0,18645229 0,21604044 GO:0055002|striated muscle cell development, ! respiratory gaseous exchange GO:0007585 47 27 0,000 0,18645229 0,21593166 ! natural killer cell activation GO:0030101 35 27 0,000 0,18645229 0,21582298 ! lipid oxidation GO:0034440 38 27 0,000 0,18645229 0,21571442 GO:0019395|fatty acid oxidation, ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,18645229 0,21560597 ! negative regulation of neuron apoptosis GO:0043524 42 27 0,000 0,18645229 0,21549762 ! gene silencing GO:0016458 41 27 0,000 0,18645229 0,21538939 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,19265119 0,22243863 ! phenol metabolic process GO:0018958 44 28 0,000 0,19265119 0,22232702 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,19265119 0,22221552 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,19265119 0,22210413 ! positive regulation of endocytosis GO:0045807 33 28 0,000 0,19265119 0,22199286 ! cholesterol homeostasis GO:0042632 46 28 0,000 0,19265119 0,2218817 GO:0055092|sterol homeostasis, ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,19265119 0,22177064 ! complement activation, classical pathway GO:0006958 36 28 0,000 0,19265119 0,2216597 ! triglyceride metabolic process GO:0006641 34 28 0,000 0,19265119 0,22154887 ! immune response-activating signal transduction GO:0002757 38 28 0,000 0,19265119 0,22143815 GO:0002764|immune response-regulating signal transduction, ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,19265119 0,22132755 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,19265119 0,22121705 ! mesoderm formation GO:0001707 46 28 0,000 0,19265119 0,22110666 ! positive regulation of multicellular organism growth GO:0040018 38 28 0,000 0,19265119 0,22099638 ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,19265119 0,22088621 ! myeloid leukocyte activation GO:0002274 39 28 0,000 0,19265119 0,22077616 ! neural tube formation GO:0001841 41 28 0,000 0,19265119 0,22066621 ! response to hydrogen peroxide GO:0042542 42 29 0,000 0,19880322 0,2275995 ! regulation of innate immune response GO:0045088 38 29 0,000 0,19880322 0,22748627 ! ovulation cycle process GO:0022602 41 29 0,000 0,19880322 0,22737315 ! protein targeting to membrane GO:0006612 53 29 0,000 0,19880322 0,22726014 ! regulation of axonogenesis GO:0050770 51 29 0,000 0,19880322 0,22714724 ! mismatch repair GO:0006298 34 29 0,000 0,19880322 0,22703446 ! regulation of protein import into nucleus GO:0042306 53 29 0,000 0,19880322 0,22692179 ! muscle cell development GO:0055001 38 29 0,000 0,19880322 0,22680922 ! formation of primary germ layer GO:0001704 48 29 0,000 0,19880322 0,22669678 ! hexose biosynthetic process GO:0019319 35 29 0,000 0,19880322 0,22658444 ! eye morphogenesis GO:0048592 51 29 0,000 0,19880322 0,22647221 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,19880322 0,2263601 ! collagen metabolic process GO:0032963 40 30 0,000 0,20490871 0,23319645 ! organic anion transport GO:0015711 51 30 0,000 0,20490871 0,23308112 ! cholesterol transport GO:0030301 46 30 0,000 0,20490871 0,23296591 GO:0015918|sterol transport, ! spliceosome assembly GO:0000245 49 30 0,000 0,20490871 0,23285081 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,20490871 0,23273582 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,20490871 0,23262094 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,20490871 0,23250618 ! ceramide metabolic process GO:0006672 43 30 0,000 0,20490871 0,23239153 ! ovulation cycle GO:0042698 43 30 0,000 0,20490871 0,232277 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,20490871 0,23216258 ! adult locomotory behavior GO:0008344 47 30 0,000 0,20490871 0,23204827 ! embryonic epithelial tube formation GO:0001838 44 30 0,000 0,20490871 0,23193407 ! regulation of microtubule-based process GO:0032886 58 30 0,000 0,20490871 0,23181999 ! response to heat GO:0009408 41 30 0,000 0,20490871 0,23170601 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,20490871 0,23159215 ! glial cell differentiation GO:0010001 55 31 0,000 0,21096802 0,23832341 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,21096802 0,23820641 ! xenobiotic metabolic process GO:0006805 44 31 0,000 0,21096802 0,23808953 ! odontogenesis GO:0042476 50 31 0,000 0,21096802 0,23797276 ! maintenance of protein location in cell GO:0032507 60 31 0,000 0,21096802 0,2378561 ! metanephros development GO:0001656 58 31 0,000 0,21096802 0,23773957 ! positive regulation of gene-specific transcription GO:0043193 47 31 0,000 0,21096802 0,23762314 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,21096802 0,23750683 ! response to mechanical stimulus GO:0009612 43 31 0,000 0,21096802 0,23739063 ! cell fate specification GO:0001708 37 31 0,000 0,21096802 0,23727455 ! biogenic amine biosynthetic process GO:0042401 44 31 0,000 0,21096802 0,23715858 ! RNA modification GO:0009451 40 31 0,000 0,21096802 0,23704272 ! regulation of ARF protein signal transduction GO:0032012 51 32 0,000 0,2169815 0,2436804 ! neutral lipid metabolic process GO:0006638 41 32 0,000 0,2169815 0,24356147 GO:0006639|acylglycerol metabolic process, ! monovalent inorganic cation homeostasis GO:0055067 45 32 0,000 0,2169815 0,24344266 ! cytokine production GO:0001816 44 32 0,000 0,2169815 0,24332397 ! monosaccharide biosynthetic process GO:0046364 38 32 0,000 0,2169815 0,24320539 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 0,000 0,2169815 0,24308693 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 0,000 0,2229495 0,24965133 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! RNA export from nucleus GO:0006405 44 33 0,000 0,2229495 0,24952985 ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,2229495 0,24940848 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,2229495 0,24928723 ! ear morphogenesis GO:0042471 42 33 0,000 0,2229495 0,2491661 ! actomyosin structure organization GO:0031032 43 33 0,000 0,2229495 0,24904509 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,2229495 0,24892419 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,2229495 0,24880342 ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 0,000 0,2229495 0,24868275 ! positive regulation of cell development GO:0010720 54 33 0,000 0,2229495 0,24856221 ! lipid homeostasis GO:0055088 55 33 0,000 0,2229495 0,24844178 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,2229495 0,24832147 ! regulation of proteolysis GO:0030162 50 33 0,000 0,2229495 0,24820128 ! negative regulation of hydrolase activity GO:0051346 50 33 0,000 0,2229495 0,2480812 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,2229495 0,24796124 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,2229495 0,24784139 ! mRNA catabolic process GO:0006402 48 34 0,000 0,22887234 0,2543026 ! regulation of neuron projection development GO:0010975 63 34 0,000 0,22887234 0,25417981 ! feeding behavior GO:0007631 45 34 0,000 0,22887234 0,25405713 ! development of primary male sexual characteristics GO:0046546 44 34 0,000 0,22887234 0,25393458 ! glycerol ether metabolic process GO:0006662 44 34 0,000 0,22887234 0,25381214 ! neuron migration GO:0001764 46 34 0,000 0,22887234 0,25368982 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,22887234 0,25356762 ! polyol metabolic process GO:0019751 44 34 0,000 0,22887234 0,25344554 ! embryonic organ development GO:0048568 45 34 0,000 0,22887234 0,25332357 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 0,000 0,22887234 0,25320172 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,23475038 0,25957974 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,23475038 0,25945501 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,23475038 0,25933039 GO:0032313|regulation of Rab GTPase activity, ! keratinocyte differentiation GO:0030216 47 35 0,000 0,23475038 0,25920589 ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,23475038 0,25908151 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,23475038 0,25895725 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 65 35 0,000 0,23475038 0,25883311 ! Rho protein signal transduction GO:0007266 51 35 0,000 0,23475038 0,25870909 ! pigment metabolic process GO:0042440 61 35 0,000 0,23475038 0,25858519 ! response to reactive oxygen species GO:0000302 55 36 0,000 0,24058394 0,26488419 ! cellular amide metabolic process GO:0043603 52 36 0,000 0,24058394 0,26475745 ! organic ether metabolic process GO:0018904 46 36 0,000 0,24058394 0,26463083 ! neural tube development GO:0021915 50 36 0,000 0,24058394 0,26450433 ! hormone-mediated signaling GO:0009755 49 36 0,000 0,24058394 0,26437796 ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,24058394 0,2642517 ! response to xenobiotic stimulus GO:0009410 50 36 0,000 0,24058394 0,26412557 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,24637337 0,27035246 GO:0006956|complement activation, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,24637337 0,27022353 ! ion transmembrane transport GO:0034220 56 37 0,000 0,24637337 0,27009473 ! ribonucleoside metabolic process GO:0009119 48 37 0,000 0,24637337 0,26996605 ! amino acid activation GO:0043038 52 37 0,000 0,24637337 0,2698375 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,24637337 0,26970907 ! gliogenesis GO:0042063 71 38 0,000 0,25211899 0,27586759 ! monocarboxylic acid transport GO:0015718 62 38 0,000 0,25211899 0,27573641 ! alcohol biosynthetic process GO:0046165 45 38 0,000 0,25211899 0,27560536 ! phagocytosis GO:0006909 60 38 0,000 0,25211899 0,27547443 ! pigmentation GO:0043473 74 38 0,000 0,25211899 0,27534362 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 0,000 0,25782113 0,2814374 ! negative regulation of protein complex disassembly GO:0043242 67 39 0,000 0,25782113 0,28130389 ! morphogenesis of embryonic epithelium GO:0016331 60 39 0,000 0,25782113 0,28117051 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 0,000 0,25782113 0,28103725 ! multicellular organismal metabolic process GO:0044236 50 39 0,000 0,25782113 0,28090412 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 0,000 0,25782113 0,28077112 ! chromatin remodeling GO:0006338 68 39 0,000 0,25782113 0,28063824 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,25782113 0,28050549 ! cell growth GO:0016049 61 39 0,000 0,25782113 0,28037286 ! regulation of actin filament polymerization GO:0030833 59 40 0,000 0,26348012 0,28639144 ! response to calcium ion GO:0051592 58 40 0,000 0,26348012 0,28625616 ! regulation of tube size GO:0035150 60 40 0,000 0,26348012 0,286121 GO:0050880|regulation of blood vessel size, ! detection of stimulus involved in sensory perception GO:0050906 50 40 0,000 0,26348012 0,28598597 ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 0,000 0,26348012 0,28585108 ! peptide metabolic process GO:0006518 56 40 0,000 0,26348012 0,2857163 ! inner ear development GO:0048839 57 40 0,000 0,26348012 0,28558166 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,26348012 0,28544714 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! T cell differentiation GO:0030217 65 40 0,000 0,26348012 0,28531275 ! B cell differentiation GO:0030183 62 40 0,000 0,26348012 0,28517848 ! epidermal cell differentiation GO:0009913 53 40 0,000 0,26348012 0,28504435 ! JAK-STAT cascade GO:0007259 53 40 0,000 0,26348012 0,28491033 ! protein amino acid lipidation GO:0006497 62 41 0,000 0,26909629 0,29084655 ! striated muscle contraction GO:0006941 62 41 0,000 0,26909629 0,29070994 ! regulation of leukocyte mediated immunity GO:0002703 62 41 0,000 0,26909629 0,29057346 ! biopolymer methylation GO:0043414 62 41 0,000 0,26909629 0,2904371 ! regulation of JNK cascade GO:0046328 58 41 0,000 0,26909629 0,29030087 ! mitochondrial transport GO:0006839 60 42 0,000 0,27466995 0,29617481 ! receptor-mediated endocytosis GO:0006898 76 42 0,000 0,27466995 0,29603602 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 0,000 0,27466995 0,29589737 ! branching morphogenesis of a tube GO:0048754 72 42 0,000 0,27466995 0,29575884 ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,27466995 0,29562044 ! excretion GO:0007588 63 42 0,000 0,27466995 0,29548217 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,27466995 0,29534403 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,27466995 0,29520602 ! regulation of gene expression, epigenetic GO:0040029 72 42 0,000 0,27466995 0,29506813 ! regulation of gene-specific transcription GO:0032583 69 43 0,000 0,28020142 0,30086987 ! neuromuscular process GO:0050905 79 43 0,000 0,28020142 0,30072947 ! tRNA processing GO:0008033 49 43 0,000 0,28020142 0,30058921 ! epithelial tube morphogenesis GO:0060562 65 43 0,000 0,28020142 0,30044907 ! methylation GO:0032259 64 43 0,000 0,28020142 0,30030907 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,28569102 0,30605 ! regulation of ion transport GO:0043269 57 44 0,000 0,28569102 0,30590752 ! cellular amino acid biosynthetic process GO:0008652 51 44 0,000 0,28569102 0,30576517 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,28569102 0,30562296 ! detection of abiotic stimulus GO:0009582 58 44 0,000 0,28569102 0,30548087 ! RNA catabolic process GO:0006401 64 45 0,000 0,29113907 0,31116165 ! regulation of translational initiation GO:0006446 64 45 0,000 0,29113907 0,31101712 ! lipoprotein biosynthetic process GO:0042158 67 45 0,000 0,29113907 0,31087273 ! cell recognition GO:0008037 58 45 0,000 0,29113907 0,31072848 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,29654588 0,31635229 ! regulation of protein complex disassembly GO:0043244 77 46 0,000 0,29654588 0,31620562 ! cell redox homeostasis GO:0045454 63 46 0,000 0,29654588 0,3160591 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,29654588 0,3159127 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,30191176 0,32148011 ! viral infectious cycle GO:0019058 71 47 0,000 0,30191176 0,32133135 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 0,000 0,30191176 0,32118272 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,30191176 0,32103423 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,30191176 0,32088588 ! regulation of neuron apoptosis GO:0043523 77 47 0,000 0,30191176 0,32073766 ! regulation of protein polymerization GO:0032271 71 47 0,000 0,30191176 0,32058958 ! chloride transport GO:0006821 67 48 0,000 0,30723701 0,32609373 ! response to temperature stimulus GO:0009266 62 48 0,000 0,30723701 0,32594332 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 0,000 0,30723701 0,32579305 ! gastrulation GO:0007369 73 48 0,000 0,30723701 0,32564291 ! heart morphogenesis GO:0003007 65 48 0,000 0,30723701 0,32549291 ! immunoglobulin mediated immune response GO:0016064 66 48 0,000 0,30723701 0,32534305 GO:0019724|B cell mediated immunity, ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,30723701 0,32519333 ! regulation of endocytosis GO:0030100 63 48 0,000 0,30723701 0,32504375 ! nuclear export GO:0051168 69 48 0,000 0,30723701 0,32489431 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,31252194 0,33033109 ! sensory perception of smell GO:0007608 61 49 0,000 0,31252194 0,33017935 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,31252194 0,33002776 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,31252194 0,3298763 ! RNA elongation GO:0006354 62 49 0,000 0,31252194 0,32972498 ! morphogenesis of a branching structure GO:0001763 86 49 0,000 0,31252194 0,3295738 ! heterocycle catabolic process GO:0046700 72 49 0,000 0,31252194 0,32942276 ! regulation of actin filament length GO:0030832 72 50 0,000 0,31776685 0,33479787 ! ear development GO:0043583 72 50 0,000 0,31776685 0,33464458 ! negative regulation of cytoskeleton organization GO:0051494 84 50 0,000 0,31776685 0,33449142 ! positive regulation of growth GO:0045927 67 50 0,000 0,31776685 0,33433841 ! regulation of multicellular organism growth GO:0040014 65 50 0,000 0,31776685 0,33418553 ! proton transport GO:0015992 75 50 0,000 0,31776685 0,3340328 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 0,000 0,31776685 0,3338802 ! hydrogen transport GO:0006818 77 51 0,000 0,32297205 0,33919439 ! adult behavior GO:0030534 80 51 0,000 0,32297205 0,33903958 ! transition metal ion transport GO:0000041 74 52 0,000 0,32813783 0,3443052 ! regulation of cellular component size GO:0032535 74 52 0,000 0,32813783 0,3441482 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,32813783 0,34399134 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,33326449 0,34920653 ! regulation of neurotransmitter levels GO:0001505 73 53 0,000 0,33326449 0,34904751 ! kidney development GO:0001822 90 53 0,000 0,33326449 0,34888863 ! detection of external stimulus GO:0009581 66 54 0,000 0,33835232 0,35405384 ! cellular amino acid catabolic process GO:0009063 74 54 0,000 0,33835232 0,35389283 ! nucleoside metabolic process GO:0009116 69 55 0,000 0,34340162 0,35901078 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,34340162 0,35884767 ! coenzyme biosynthetic process GO:0009108 67 57 0,000 0,35338576 0,36911319 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,35338576 0,36894564 ! camera-type eye development GO:0043010 88 57 0,000 0,35338576 0,36877824 ! secondary metabolic process GO:0019748 84 57 0,000 0,35338576 0,368611 ! viral reproductive process GO:0022415 87 58 0,000 0,35832118 0,37358963 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 0,000 0,36321921 0,37852478 ! activation of MAPK activity GO:0000187 84 59 0,000 0,36321921 0,37835334 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,36321921 0,37818207 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 0,000 0,36808013 0,38306982 ! embryonic limb morphogenesis GO:0030326 86 60 0,000 0,36808013 0,38289657 GO:0035113|embryonic appendage morphogenesis, ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,36808013 0,38272347 ! regulation of vesicle-mediated transport GO:0060627 79 60 0,000 0,36808013 0,38255052 ! regulation of cellular response to stress GO:0080135 85 61 0,000 0,37290423 0,38738921 ! lipoprotein metabolic process GO:0042157 89 61 0,000 0,37290423 0,38721432 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,37290423 0,38703958 ! extracellular matrix organization GO:0030198 103 61 0,000 0,37290423 0,38686501 ! amine catabolic process GO:0009310 90 62 0,000 0,37769177 0,39165512 ! neurotransmitter transport GO:0006836 81 62 0,000 0,37769177 0,39147862 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,37769177 0,39130228 ! lymphocyte mediated immunity GO:0002449 88 62 0,000 0,37769177 0,3911261 ! cAMP-mediated signaling GO:0019933 97 63 0,000 0,38244303 0,39586812 ! viral reproduction GO:0016032 92 63 0,000 0,38244303 0,39569004 ! appendage morphogenesis GO:0035107 93 64 0,000 0,38715829 0,40038852 GO:0035108|limb morphogenesis, ! regulation of actin cytoskeleton organization GO:0032956 97 64 0,000 0,38715829 0,40020857 ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,38715829 0,40002878 ! appendage development GO:0048736 94 65 0,000 0,39183781 0,40468207 GO:0060173|limb development, ! B cell activation GO:0042113 104 65 0,000 0,39183781 0,40450043 ! activation of immune response GO:0002253 83 65 0,000 0,39183781 0,40431896 ! regulation of actin filament-based process GO:0032970 99 66 0,000 0,39648187 0,40892749 ! antigen processing and presentation GO:0019882 96 66 0,000 0,39648187 0,4087442 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,40109073 0,41331034 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,40566466 0,41783641 ! intracellular protein transmembrane transport GO:0065002 102 68 0,000 0,40566466 0,41764938 ! regulation of Ras GTPase activity GO:0032318 110 68 0,000 0,40566466 0,41746251 ! rhythmic process GO:0048511 105 68 0,000 0,40566466 0,41727581 ! inorganic anion transport GO:0015698 93 68 0,000 0,40566466 0,41708928 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,41020391 0,42156792 ! response to metal ion GO:0010038 103 70 0,000 0,41470876 0,42600721 ! eye development GO:0001654 111 70 0,000 0,41470876 0,42581703 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 0,000 0,41470876 0,42562702 ! lymphocyte differentiation GO:0030098 113 71 0,000 0,41917945 0,43002352 ! regulation of blood pressure GO:0008217 107 73 0,000 0,42801941 0,43889641 ! tube morphogenesis GO:0035239 118 73 0,000 0,42801941 0,43870083 ! cellular lipid catabolic process GO:0044242 105 73 0,000 0,42801941 0,43850541 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,43238919 0,44278501 ! digestion GO:0007586 97 74 0,000 0,43238919 0,44258796 ! response to inorganic substance GO:0010035 115 75 0,000 0,43672583 0,44682803 ! cofactor biosynthetic process GO:0051188 92 75 0,000 0,43672583 0,44662935 ! amine biosynthetic process GO:0009309 97 76 0,000 0,44102959 0,45083024 ! tRNA metabolic process GO:0006399 95 76 0,000 0,44102959 0,45062996 ! response to unfolded protein GO:0006986 99 76 0,000 0,44102959 0,45042986 ! regulation of adenylate cyclase activity GO:0045761 131 77 0,000 0,4453007 0,45459015 ! one-carbon metabolic process GO:0006730 110 77 0,000 0,4453007 0,45438847 ! carbohydrate biosynthetic process GO:0016051 97 77 0,000 0,4453007 0,45418697 ! nitrogen compound catabolic process GO:0044270 114 78 0,000 0,44953943 0,45830704 ! regulation of cyclase activity GO:0031279 132 78 0,000 0,44953943 0,45810398 ! regulation of cAMP biosynthetic process GO:0030817 136 79 0,000 0,453746 0,46218592 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,453746 0,46198132 ! T cell activation GO:0042110 134 79 0,000 0,453746 0,46177691 ! regulation of lyase activity GO:0051339 133 79 0,000 0,453746 0,46157267 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,453746 0,46136862 ! chromatin assembly GO:0031497 102 80 0,000 0,45792067 0,46540767 GO:0006334|nucleosome assembly, ! regulation of GTPase activity GO:0043087 129 80 0,000 0,45792067 0,4652021 ! regulation of cAMP metabolic process GO:0030814 141 81 0,000 0,46206368 0,46920373 ! mRNA transport GO:0051028 121 81 0,000 0,46206368 0,46899667 ! response to protein stimulus GO:0051789 111 81 0,000 0,46206368 0,46878979 ! vitamin metabolic process GO:0006766 103 81 0,000 0,46206368 0,46858309 ! detection of stimulus GO:0051606 108 82 0,000 0,46617525 0,47254433 ! regulation of nucleotide biosynthetic process GO:0030808 141 83 0,000 0,47025564 0,47647047 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! biogenic amine metabolic process GO:0006576 121 83 0,000 0,47025564 0,47626066 ! protein-DNA complex assembly GO:0065004 107 84 0,000 0,47430507 0,48015037 ! transcription initiation GO:0006352 118 85 0,000 0,47832377 0,48400558 ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 0,000 0,48231198 0,48782654 ! nucleosome organization GO:0034728 114 87 0,000 0,48626993 0,49161356 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 0,000 0,48626993 0,49139756 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cellular defense response GO:0006968 102 87 0,000 0,48626993 0,49118175 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 0,000 0,49019785 0,49493198 ! carboxylic acid catabolic process GO:0046395 122 88 0,000 0,49019785 0,49471481 GO:0016054|organic acid catabolic process, ! establishment of RNA localization GO:0051236 128 88 0,000 0,49019785 0,49449783 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 0,000 0,49409596 0,49821162 ! regulation of nucleotide metabolic process GO:0006140 150 89 0,000 0,49409596 0,4979933 ! hormone metabolic process GO:0042445 121 90 0,000 0,49796448 0,5016725 ! RNA localization GO:0006403 135 91 0,000 0,50180364 0,50531891 ! ATP metabolic process GO:0046034 137 91 0,000 0,50180364 0,50509776 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 0,000 0,50561367 0,50871016 ! positive regulation of immune response GO:0050778 121 92 0,000 0,50561367 0,50848773 ! sulfur metabolic process GO:0006790 118 92 0,000 0,50561367 0,50826549 ! regulation of cytoskeleton organization GO:0051493 154 93 0,000 0,50939477 0,51184271 ! electron transport chain GO:0022900 123 94 0,000 0,51314717 0,51538799 ! response to oxidative stress GO:0006979 141 94 0,000 0,51314717 0,51516303 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 0,000 0,52056673 0,52238372 ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,52423431 0,52583468 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 0,000 0,52423431 0,52560546 ! calcium ion transport GO:0006816 167 99 0,000 0,53148615 0,53264407 ! homophilic cell adhesion GO:0007156 149 100 0,000 0,53507082 0,536003 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 0,000 0,53507082 0,53576965 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 0,000 0,53507082 0,53553651 ! divalent metal ion transport GO:0070838 171 100 0,000 0,53507082 0,53530356 ! Ras protein signal transduction GO:0007265 162 100 0,000 0,53507082 0,53507082