pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6827-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 5,000 6,55E-12 1,576E-08 ! negative regulation of phosphorylation GO:0042326 47 24 5,000 3,929E-09 4,726E-06 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 5,000 6,657E-09 5,339E-06 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of lipid kinase activity GO:0043550 13 7 3,000 3,548E-08 2,134E-05 ! positive regulation of locomotion GO:0040017 39 21 4,000 1,083E-07 5,211E-05 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! negative regulation of protein kinase activity GO:0006469 130 67 6,000 1,143E-07 4,582E-05 ! induction of positive chemotaxis GO:0050930 15 9 3,000 1,266E-07 4,351E-05 ! negative regulation of kinase activity GO:0033673 131 68 6,000 1,268E-07 3,812E-05 ! regulation of chemotaxis GO:0050920 40 22 4,000 1,395E-07 3,73E-05 ! negative regulation of transferase activity GO:0051348 140 72 6,000 1,89E-07 4,546E-05 ! protein sumoylation GO:0016925 15 10 3,000 2,1E-07 4,594E-05 ! regulation of behavior GO:0050795 43 24 4,000 2,231E-07 4,473E-05 ! regulation of transcription factor activity GO:0051090 126 74 6,000 2,286E-07 4,232E-05 GO:0090046|regulation of transcription regulator activity, ! G1/S transition of mitotic cell cycle GO:0000082 115 46 5,000 2,464E-07 4,235E-05 ! regulation of positive chemotaxis GO:0050926 19 12 3,000 4,907E-07 7,87E-05 GO:0050927|positive regulation of positive chemotaxis, ! regulation of DNA binding GO:0051101 155 88 6,000 7,543E-07 1,134E-04 ! negative regulation of transcription regulator activity GO:0090048 58 31 4,000 8,635E-07 1,222E-04 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 3,000 9,834E-07 1,314E-04 ! regulation of protein complex assembly GO:0043254 117 61 5,000 1,361E-06 1,723E-04 ! regulation of protein localization GO:0032880 176 97 6,000 1,462E-06 1,759E-04 ! cell cycle arrest GO:0007050 213 100 6,000 1,796E-06 2,057E-04 ! Notch receptor processing GO:0007220 8 5 2,000 1,815E-06 1,985E-04 ! establishment or maintenance of cell polarity GO:0007163 83 37 4,000 2,155E-06 2,254E-04 ! negative regulation of DNA binding GO:0043392 68 37 4,000 2,155E-06 2,16E-04 ! positive regulation of protein complex assembly GO:0031334 32 17 3,000 2,307E-06 2,22E-04 ! negative regulation of binding GO:0051100 72 40 4,000 3,208E-06 2,968E-04 ! myoblast cell fate commitment GO:0048625 16 6 2,000 3,615E-06 3,221E-04 ! nuclear migration GO:0007097 12 6 2,000 3,615E-06 3,106E-04 ! positive regulation of pseudopodium assembly GO:0031274 14 6 2,000 3,615E-06 2,999E-04 GO:0031272|regulation of pseudopodium assembly, ! positive regulation of response to external stimulus GO:0032103 77 43 4,000 4,628E-06 3,712E-04 ! regulation of epithelial cell proliferation GO:0050678 111 43 4,000 4,628E-06 3,592E-04 ! pancreas development GO:0031016 35 20 3,000 4,634E-06 3,484E-04 ! positive regulation of inflammatory response GO:0050729 35 21 3,000 5,699E-06 4,155E-04 ! induction of apoptosis by intracellular signals GO:0008629 93 45 4,000 5,82E-06 4,119E-04 ! regulation of protein export from nucleus GO:0046825 10 7 2,000 6,3E-06 4,331E-04 ! amyloid precursor protein catabolic process GO:0042987 11 7 2,000 6,3E-06 4,21E-04 ! macrophage differentiation GO:0030225 11 7 2,000 6,3E-06 4,097E-04 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 2,000 6,3E-06 3,989E-04 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 3,000 6,934E-06 4,278E-04 ! regulation of mast cell proliferation GO:0070666 81 48 4,000 8,045E-06 4,839E-04 ! positive regulation of insulin secretion GO:0032024 15 8 2,000 1,004E-05 5,89E-04 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 2,000 1,004E-05 5,75E-04 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 2,000 1,004E-05 5,616E-04 ! establishment of nucleus localization GO:0040023 16 8 2,000 1,004E-05 5,489E-04 ! regulation of leukocyte proliferation GO:0070663 88 51 4,000 1,088E-05 5,82E-04 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! membrane fusion GO:0006944 110 52 4,000 1,199E-05 6,27E-04 ! amyloid precursor protein metabolic process GO:0042982 14 9 2,000 1,499E-05 7,675E-04 ! motor axon guidance GO:0008045 16 9 2,000 1,499E-05 7,515E-04 ! interphase of mitotic cell cycle GO:0051329 209 95 5,000 1,815E-05 8,911E-04 ! negative regulation of protein modification process GO:0031400 60 28 3,000 1,89E-05 9,093E-04 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 2,000 2,133E-05 1,006E-03 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 2,000 2,133E-05 9,868E-04 ! positive regulation of leukocyte migration GO:0002687 25 10 2,000 2,133E-05 9,682E-04 ! interphase GO:0051325 213 98 5,000 2,167E-05 9,656E-04 ! establishment of organelle localization GO:0051656 109 59 4,000 2,236E-05 9,781E-04 ! regulation of B cell activation GO:0050864 50 30 3,000 2,507E-05 1,077E-03 ! chondrocyte differentiation GO:0002062 24 11 2,000 2,92E-05 1,233E-03 ! positive regulation of peptide secretion GO:0002793 22 11 2,000 2,92E-05 1,211E-03 ! regulation of leukocyte migration GO:0002685 26 11 2,000 2,92E-05 1,191E-03 ! negative regulation of glucose import GO:0046325 17 11 2,000 2,92E-05 1,171E-03 GO:0010829|negative regulation of glucose transport, ! nucleus localization GO:0051647 19 11 2,000 2,92E-05 1,152E-03 ! leukocyte chemotaxis GO:0030595 50 33 3,000 3,693E-05 1,433E-03 GO:0060326|cell chemotaxis, ! regulation of B cell proliferation GO:0030888 20 12 2,000 3,877E-05 1,481E-03 ! regulation of cell projection assembly GO:0060491 30 12 2,000 3,877E-05 1,458E-03 ! membrane protein proteolysis GO:0033619 25 12 2,000 3,877E-05 1,435E-03 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of hormone metabolic process GO:0032350 26 12 2,000 3,877E-05 1,413E-03 ! negative regulation of mast cell proliferation GO:0070667 23 12 2,000 3,877E-05 1,392E-03 GO:0042130|negative regulation of T cell proliferation, ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 4,000 4,157E-05 1,471E-03 ! double-strand break repair via homologous recombination GO:0000724 19 13 2,000 5,019E-05 1,75E-03 GO:0000725|recombinational repair, ! androgen receptor signaling pathway GO:0030521 74 36 3,000 5,246E-05 1,803E-03 ! organelle localization GO:0051640 136 74 4,000 6,714E-05 2,275E-03 ! glycoprotein catabolic process GO:0006516 26 15 2,000 7,918E-05 2,646E-03 ! regulation of the force of heart contraction GO:0002026 26 15 2,000 7,918E-05 2,61E-03 ! epithelial to mesenchymal transition GO:0001837 28 15 2,000 7,918E-05 2,575E-03 ! regulation of hormone secretion GO:0046883 62 40 3,000 7,996E-05 2,565E-03 ! regulation of T cell differentiation GO:0045580 70 41 3,000 8,821E-05 2,792E-03 ! regulation of T cell proliferation GO:0042129 71 41 3,000 8,821E-05 2,756E-03 ! positive regulation of phosphorylation GO:0042327 129 79 4,000 9,181E-05 2,832E-03 ! filopodium assembly GO:0046847 32 16 2,000 9,705E-05 2,956E-03 ! negative regulation of leukocyte proliferation GO:0070664 31 16 2,000 9,705E-05 2,919E-03 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of phosphorus metabolic process GO:0010562 136 81 4,000 1,034E-04 3,072E-03 GO:0045937|positive regulation of phosphate metabolic process, ! myoblast differentiation GO:0045445 45 17 2,000 1,174E-04 3,443E-03 ! neutrophil chemotaxis GO:0030593 27 17 2,000 1,174E-04 3,402E-03 ! microspike assembly GO:0030035 36 17 2,000 1,174E-04 3,361E-03 ! negative regulation of transport GO:0051051 153 84 4,000 1,229E-04 3,479E-03 ! leukocyte migration GO:0050900 68 45 3,000 1,275E-04 3,567E-03 ! positive regulation of defense response GO:0031349 76 47 3,000 1,513E-04 4,183E-03 ! positive regulation of cell cycle GO:0045787 89 48 3,000 1,643E-04 4,492E-03 ! regulation of inflammatory response GO:0050727 75 48 3,000 1,643E-04 4,441E-03 ! regulation of lymphocyte differentiation GO:0045619 81 48 3,000 1,643E-04 4,392E-03 ! positive regulation of hormone secretion GO:0046887 32 19 2,000 1,658E-04 4,384E-03 ! plasma membrane fusion GO:0045026 28 19 2,000 1,658E-04 4,337E-03 ! regulation of action potential GO:0001508 95 49 3,000 1,781E-04 4,608E-03 ! regulation of glucose import GO:0046324 29 20 2,000 1,943E-04 4,973E-03 GO:0010827|regulation of glucose transport, ! negative regulation of T cell activation GO:0050868 40 20 2,000 1,943E-04 4,92E-03 ! regulation of angiogenesis GO:0045765 114 52 3,000 2,246E-04 5,628E-03 ! regulation of muscle contraction GO:0006937 81 52 3,000 2,246E-04 5,57E-03 ! cartilage development GO:0051216 90 52 3,000 2,246E-04 5,513E-03 ! inactivation of MAPK activity GO:0000188 39 21 2,000 2,257E-04 5,485E-03 ! positive regulation of osteoblast differentiation GO:0045669 49 21 2,000 2,257E-04 5,43E-03 ! regulation of DNA metabolic process GO:0051052 178 97 4,000 2,417E-04 5,758E-03 ! response to UV GO:0009411 104 53 3,000 2,418E-04 5,704E-03 ! positive regulation of B cell activation GO:0050871 38 22 2,000 2,602E-04 6,079E-03 ! skeletal muscle tissue development GO:0007519 186 99 4,000 2,658E-04 6,149E-03 GO:0060538|skeletal muscle organ development, ! myeloid leukocyte differentiation GO:0002573 40 23 2,000 2,98E-04 6,829E-03 ! platelet activation GO:0030168 37 23 2,000 2,98E-04 6,765E-03 ! skeletal muscle fiber development GO:0048741 111 56 3,000 2,993E-04 6,73E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 3,000 3,205E-04 7,139E-03 ! regulation of bone remodeling GO:0046850 137 57 3,000 3,205E-04 7,074E-03 ! muscle fiber development GO:0048747 112 57 3,000 3,205E-04 7,009E-03 ! positive regulation of cell migration GO:0030335 126 57 3,000 3,205E-04 6,946E-03 ! negative regulation of bone resorption GO:0045779 10 5 1,000 3,206E-04 6,888E-03 ! regulation of collagen biosynthetic process GO:0032965 6 5 1,000 3,206E-04 6,827E-03 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 1,000 3,206E-04 6,767E-03 ! response to protozoan GO:0001562 10 5 1,000 3,206E-04 6,708E-03 ! neutrophil mediated immunity GO:0002446 7 5 1,000 3,206E-04 6,65E-03 ! microvillus organization GO:0032528 7 5 1,000 3,206E-04 6,593E-03 GO:0030033|microvillus assembly, ! morphogenesis of an epithelial sheet GO:0002011 11 5 1,000 3,206E-04 6,538E-03 ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 3,206E-04 6,483E-03 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 1,000 3,206E-04 6,429E-03 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 1,000 3,206E-04 6,376E-03 ! meiotic chromosome segregation GO:0045132 7 5 1,000 3,206E-04 6,323E-03 ! decidualization GO:0046697 11 5 1,000 3,206E-04 6,272E-03 ! mitotic recombination GO:0006312 9 5 1,000 3,206E-04 6,221E-03 ! positive regulation of chemokine production GO:0032722 8 5 1,000 3,206E-04 6,172E-03 ! inner cell mass cell proliferation GO:0001833 5 5 1,000 3,206E-04 6,123E-03 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 1,000 3,206E-04 6,074E-03 ! stem cell division GO:0017145 11 5 1,000 3,206E-04 6,027E-03 GO:0048103|somatic stem cell division, ! regulation of tissue remodeling GO:0034103 140 58 3,000 3,427E-04 6,391E-03 ! positive regulation of secretion GO:0051047 95 59 3,000 3,66E-04 6,773E-03 ! myelination GO:0042552 45 25 2,000 3,838E-04 7,049E-03 ! vasculogenesis GO:0001570 46 25 2,000 3,838E-04 6,996E-03 ! regulation of insulin secretion GO:0050796 37 25 2,000 3,838E-04 6,943E-03 ! regulation of heart contraction GO:0008016 110 60 3,000 3,904E-04 7,009E-03 ! protein amino acid autophosphorylation GO:0046777 141 60 3,000 3,904E-04 6,958E-03 ! mesoderm development GO:0007498 119 61 3,000 4,159E-04 7,358E-03 ! insulin receptor signaling pathway GO:0008286 64 26 2,000 4,321E-04 7,588E-03 ! regulation of osteoblast differentiation GO:0045667 65 26 2,000 4,321E-04 7,533E-03 ! blastocyst development GO:0001824 49 26 2,000 4,321E-04 7,479E-03 ! regulation of lipid metabolic process GO:0019216 115 63 3,000 4,706E-04 8,087E-03 ! steroid hormone receptor signaling pathway GO:0030518 129 63 3,000 4,706E-04 8,03E-03 ! male meiosis GO:0007140 7 6 1,000 4,791E-04 8,118E-03 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 1,000 4,791E-04 8,062E-03 GO:0033135|regulation of peptidyl-serine phosphorylation, ! regulation of immunoglobulin secretion GO:0051023 6 6 1,000 4,791E-04 8,006E-03 ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 1,000 4,791E-04 7,95E-03 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! regulation of collagen metabolic process GO:0010712 9 6 1,000 4,791E-04 7,896E-03 ! establishment of spindle localization GO:0051293 12 6 1,000 4,791E-04 7,842E-03 GO:0051653|spindle localization, ! negative regulation of gliogenesis GO:0014014 18 6 1,000 4,791E-04 7,789E-03 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 14 6 1,000 4,791E-04 7,737E-03 ! response to UV-C GO:0010225 11 6 1,000 4,791E-04 7,685E-03 ! enucleate erythrocyte differentiation GO:0043353 12 6 1,000 4,791E-04 7,634E-03 ! neutrophil homeostasis GO:0001780 10 6 1,000 4,791E-04 7,584E-03 ! salivary gland morphogenesis GO:0007435 13 6 1,000 4,791E-04 7,535E-03 ! organ or tissue specific immune response GO:0002251 7 6 1,000 4,791E-04 7,486E-03 ! maternal placenta development GO:0001893 12 6 1,000 4,791E-04 7,437E-03 ! negative regulation of B cell activation GO:0050869 13 6 1,000 4,791E-04 7,39E-03 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 2,000 4,84E-04 7,418E-03 ! positive regulation of cell projection organization GO:0031346 58 27 2,000 4,84E-04 7,371E-03 ! fat cell differentiation GO:0045444 50 27 2,000 4,84E-04 7,324E-03 ! negative regulation of lymphocyte activation GO:0051250 53 27 2,000 4,84E-04 7,279E-03 ! positive regulation of cell motion GO:0051272 146 64 3,000 4,997E-04 7,468E-03 ! myeloid cell differentiation GO:0030099 111 65 3,000 5,301E-04 7,874E-03 ! cell projection assembly GO:0030031 120 66 3,000 5,619E-04 8,293E-03 ! negative regulation of cell growth GO:0030308 132 67 3,000 5,949E-04 8,727E-03 ! chromosome segregation GO:0007059 113 67 3,000 5,949E-04 8,675E-03 ! negative regulation of protein complex assembly GO:0031333 59 29 2,000 5,996E-04 8,691E-03 ! regulation of peptide secretion GO:0002791 47 29 2,000 5,996E-04 8,639E-03 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 3,000 6,293E-04 9,012E-03 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 2,000 6,635E-04 9,445E-03 ! cell junction assembly GO:0034329 78 30 2,000 6,635E-04 9,39E-03 ! ensheathment of neurons GO:0007272 57 30 2,000 6,635E-04 9,335E-03 GO:0008366|axon ensheathment, ! negative regulation of leukocyte activation GO:0002695 56 30 2,000 6,635E-04 9,281E-03 ! cell cycle checkpoint GO:0000075 137 69 3,000 6,65E-04 9,249E-03 ! negative regulation of cell size GO:0045792 134 69 3,000 6,65E-04 9,196E-03 ! cytokinesis during cell cycle GO:0033205 11 7 1,000 6,683E-04 9,188E-03 ! N-terminal protein amino acid acetylation GO:0006474 13 7 1,000 6,683E-04 9,136E-03 ! mRNA stabilization GO:0048255 18 7 1,000 6,683E-04 9,084E-03 GO:0043489|RNA stabilization, ! positive regulation of mitotic cell cycle GO:0045931 12 7 1,000 6,683E-04 9,033E-03 ! centrosome duplication GO:0051298 13 7 1,000 6,683E-04 8,983E-03 ! cranial nerve morphogenesis GO:0021602 11 7 1,000 6,683E-04 8,933E-03 ! vesicle fusion GO:0006906 17 7 1,000 6,683E-04 8,883E-03 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 1,000 6,683E-04 8,834E-03 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 1,000 6,683E-04 8,786E-03 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 1,000 6,683E-04 8,738E-03 ! defense response to Gram-negative bacterium GO:0050829 9 7 1,000 6,683E-04 8,691E-03 ! peptide transport GO:0015833 55 31 2,000 7,315E-04 9,462E-03 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 3,000 7,81E-04 0,01004858 ! negative regulation of MAP kinase activity GO:0043407 69 32 2,000 8,038E-04 0,01028658 ! axon guidance GO:0007411 139 73 3,000 8,226E-04 0,01047219 ! meiosis GO:0007126 121 74 3,000 8,658E-04 0,01096375 GO:0051327|M phase of meiotic cell cycle, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 8,877E-04 0,01118206 ! oligopeptide transport GO:0006857 15 8 1,000 8,877E-04 0,01112382 ! T-helper 1 type immune response GO:0042088 12 8 1,000 8,877E-04 0,01106619 ! ER overload response GO:0006983 12 8 1,000 8,877E-04 0,01100914 ! positive regulation of endothelial cell migration GO:0010595 19 8 1,000 8,877E-04 0,01095269 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 1,000 8,877E-04 0,01089681 ! cerebral cortex neuron differentiation GO:0021895 16 8 1,000 8,877E-04 0,01084149 ! regulation of vascular permeability GO:0043114 12 8 1,000 8,877E-04 0,01078674 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 1,000 8,877E-04 0,01073253 ! osteoblast development GO:0002076 16 8 1,000 8,877E-04 0,01067887 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 1,000 8,877E-04 0,01062574 ! myeloid cell homeostasis GO:0002262 13 8 1,000 8,877E-04 0,01057314 ! blastocyst growth GO:0001832 19 8 1,000 8,877E-04 0,01052105 ! trophectodermal cell differentiation GO:0001829 13 8 1,000 8,877E-04 0,01046948 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 1,000 8,877E-04 0,01041841 ! phosphoinositide-mediated signaling GO:0048015 131 75 3,000 9,105E-04 0,01063478 ! meiotic cell cycle GO:0051321 122 75 3,000 9,105E-04 0,0105834 ! placenta development GO:0001890 53 34 2,000 9,616E-04 0,01112346 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 2,000 1,047E-03 0,01205752 ! regulation of synaptic plasticity GO:0048167 64 35 2,000 1,047E-03 0,0120001 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 3,000 1,106E-03 0,01260997 ! regulation of developmental growth GO:0048638 15 9 1,000 1,137E-03 0,01290419 ! Golgi to endosome transport GO:0006895 23 9 1,000 1,137E-03 0,01284361 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 1,000 1,137E-03 0,01278359 ! retrograde transport, endosome to Golgi GO:0042147 24 9 1,000 1,137E-03 0,01272413 ! determination of anterior/posterior axis, embryo GO:0008595 16 9 1,000 1,137E-03 0,01266523 GO:0007351|tripartite regional subdivision, ! regulation of macrophage differentiation GO:0045649 15 9 1,000 1,137E-03 0,01260686 ! regulation of synaptogenesis GO:0051963 15 9 1,000 1,137E-03 0,01254903 ! cell junction organization GO:0034330 86 36 2,000 1,138E-03 0,01250064 ! negative regulation of cell activation GO:0050866 65 36 2,000 1,138E-03 0,01244382 ! muscle cell differentiation GO:0042692 159 80 3,000 1,159E-03 0,01261718 ! meiosis I GO:0007127 65 37 2,000 1,233E-03 0,0133638 ! cellular response to insulin stimulus GO:0032869 82 37 2,000 1,233E-03 0,01330388 ! carbohydrate homeostasis GO:0033500 53 38 2,000 1,333E-03 0,01431974 GO:0042593|glucose homeostasis, ! positive regulation of leukocyte proliferation GO:0070665 62 38 2,000 1,333E-03 0,01425609 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! negative regulation of growth GO:0045926 155 84 3,000 1,389E-03 0,01478871 ! regulation of ligase activity GO:0051340 142 84 3,000 1,389E-03 0,01472356 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 1,416E-03 0,01494203 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 1,000 1,416E-03 0,01487678 ! lung alveolus development GO:0048286 26 10 1,000 1,416E-03 0,0148121 ! regulation of chemokine biosynthetic process GO:0045073 12 10 1,000 1,416E-03 0,01474798 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 1,000 1,416E-03 0,01468441 ! myeloid leukocyte mediated immunity GO:0002444 14 10 1,000 1,416E-03 0,01462138 ! multicellular organism growth GO:0035264 18 10 1,000 1,416E-03 0,0145589 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 1,000 1,416E-03 0,01449695 ! regulation of bone resorption GO:0045124 25 10 1,000 1,416E-03 0,01443552 ! regulation of gliogenesis GO:0014013 23 10 1,000 1,416E-03 0,01437461 GO:0045685|regulation of glial cell differentiation, ! blastoderm segmentation GO:0007350 18 10 1,000 1,416E-03 0,01431421 ! positive regulation of interleukin-6 production GO:0032755 14 10 1,000 1,416E-03 0,01425432 ! salivary gland development GO:0007431 27 10 1,000 1,416E-03 0,01419493 ! positive regulation of acute inflammatory response GO:0002675 16 10 1,000 1,416E-03 0,01413603 ! oocyte development GO:0048599 17 10 1,000 1,416E-03 0,01407761 ! blastocyst formation GO:0001825 17 10 1,000 1,416E-03 0,01401968 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 1,000 1,416E-03 0,01396222 ! localization within membrane GO:0051668 20 10 1,000 1,416E-03 0,01390523 ! mammary gland development GO:0030879 86 39 2,000 1,438E-03 0,01406679 ! segmentation GO:0035282 67 39 2,000 1,438E-03 0,01400984 ! regulation of action potential in neuron GO:0019228 73 39 2,000 1,438E-03 0,01395335 ! mesenchymal cell development GO:0014031 87 40 2,000 1,548E-03 0,01496147 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! cytokinesis GO:0000910 72 40 2,000 1,548E-03 0,01490163 ! regulation of protein transport GO:0051223 154 87 3,000 1,581E-03 0,01515919 GO:0070201|regulation of establishment of protein localization, ! positive regulation of protein modification process GO:0031401 136 88 3,000 1,649E-03 0,01574841 ! gland development GO:0048732 206 88 3,000 1,649E-03 0,01568617 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 1,000 1,724E-03 0,01633162 ! blood vessel remodeling GO:0001974 29 11 1,000 1,724E-03 0,01626757 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 1,000 1,724E-03 0,01620403 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 1,000 1,724E-03 0,01614098 ! peptide or protein amino-terminal blocking GO:0018409 21 11 1,000 1,724E-03 0,01607842 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 1,000 1,724E-03 0,01601634 ! embryonic axis specification GO:0000578 18 11 1,000 1,724E-03 0,01595474 ! neuroblast proliferation GO:0007405 24 11 1,000 1,724E-03 0,01589361 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 1,000 1,724E-03 0,01583294 ! oocyte differentiation GO:0009994 18 11 1,000 1,724E-03 0,01577274 ! anterior/posterior axis specification GO:0009948 18 11 1,000 1,724E-03 0,015713 ! defense response to Gram-positive bacterium GO:0050830 13 11 1,000 1,724E-03 0,0156537 ! sequestering of metal ion GO:0051238 14 11 1,000 1,724E-03 0,01559485 ! regulation of synapse organization GO:0050807 17 11 1,000 1,724E-03 0,01553645 ! positive regulation of transcription factor activity GO:0051091 62 42 2,000 1,784E-03 0,01601755 GO:0090047|positive regulation of transcription regulator activity, ! regulation of intracellular protein transport GO:0033157 80 42 2,000 1,784E-03 0,01595801 ! ossification GO:0001503 188 90 3,000 1,792E-03 0,01596462 ! regulation of cell cycle process GO:0010564 149 90 3,000 1,792E-03 0,01590571 ! bone development GO:0060348 189 91 3,000 1,866E-03 0,01650293 ! regulation of defense response GO:0031347 149 92 3,000 1,942E-03 0,01711427 ! regulation of membrane potential GO:0042391 164 93 3,000 2,02E-03 0,01773983 ! double-strand break repair GO:0006302 81 44 2,000 2,041E-03 0,0178587 ! cartilage condensation GO:0001502 20 12 1,000 2,061E-03 0,01796819 ! hippocampus development GO:0021766 26 12 1,000 2,061E-03 0,01790332 ! drug transport GO:0015893 16 12 1,000 2,061E-03 0,01783892 ! focal adhesion formation GO:0048041 35 12 1,000 2,061E-03 0,01777498 ! entry into host cell GO:0030260 32 12 1,000 2,061E-03 0,0177115 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! cranial nerve development GO:0021545 20 12 1,000 2,061E-03 0,01764847 ! histone acetylation GO:0016573 26 12 1,000 2,061E-03 0,01758589 ! autonomic nervous system development GO:0048483 24 12 1,000 2,061E-03 0,01752375 ! gland morphogenesis GO:0022612 29 12 1,000 2,061E-03 0,01746204 ! peptidyl-lysine modification GO:0018205 21 12 1,000 2,061E-03 0,01740077 ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 1,000 2,061E-03 0,01733993 ! regulation of synapse structure and activity GO:0050803 18 12 1,000 2,061E-03 0,01727951 ! regulation of T cell activation GO:0050863 158 94 3,000 2,101E-03 0,01755009 ! regulation of Rho protein signal transduction GO:0035023 213 95 3,000 2,183E-03 0,01817787 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 2,000 2,32E-03 0,01924923 ! response to insulin stimulus GO:0032868 95 46 2,000 2,32E-03 0,01918308 ! positive regulation of protein transport GO:0051222 72 46 2,000 2,32E-03 0,01911738 ! regulation of chemokine production GO:0032642 18 13 1,000 2,427E-03 0,01992812 ! organelle fusion GO:0048284 32 13 1,000 2,427E-03 0,01986034 ! endocrine pancreas development GO:0031018 22 13 1,000 2,427E-03 0,01979301 ! regulation of skeletal muscle fiber development GO:0048742 32 13 1,000 2,427E-03 0,01972614 ! cell-cell junction assembly GO:0007043 27 13 1,000 2,427E-03 0,01965973 ! response to X-ray GO:0010165 25 13 1,000 2,427E-03 0,01959375 ! cellular carbohydrate catabolic process GO:0044275 15 13 1,000 2,427E-03 0,01952822 ! exocrine system development GO:0035272 32 13 1,000 2,427E-03 0,01946313 ! regulation of monooxygenase activity GO:0032768 33 13 1,000 2,427E-03 0,01939847 ! regulation of acute inflammatory response GO:0002673 21 13 1,000 2,427E-03 0,01933423 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 1,000 2,427E-03 0,01927042 ! regulation of mRNA stability GO:0043488 31 13 1,000 2,427E-03 0,01920704 ! embryonic placenta development GO:0001892 23 13 1,000 2,427E-03 0,01914406 ! endosome transport GO:0016197 108 47 2,000 2,468E-03 0,01940546 ! positive regulation of DNA binding GO:0043388 73 47 2,000 2,468E-03 0,01934225 ! Golgi vesicle transport GO:0048193 207 99 3,000 2,537E-03 0,01981632 ! Notch signaling pathway GO:0007219 96 48 2,000 2,622E-03 0,02041291 ! induction of apoptosis by extracellular signals GO:0008624 89 49 2,000 2,781E-03 0,02158389 ! DNA-dependent DNA replication GO:0006261 74 49 2,000 2,781E-03 0,02151449 ! N-terminal protein amino acid modification GO:0031365 27 14 1,000 2,821E-03 0,02175188 ! regulation of S phase GO:0033261 23 14 1,000 2,821E-03 0,02168238 ! regulation of mRNA processing GO:0050684 24 14 1,000 2,821E-03 0,02161333 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 1,000 2,821E-03 0,02154472 ! regulation of T-helper 2 type immune response GO:0002828 24 14 1,000 2,821E-03 0,02147654 ! response to gamma radiation GO:0010332 28 14 1,000 2,821E-03 0,02140879 ! regulation of RNA stability GO:0043487 32 14 1,000 2,821E-03 0,02134146 ! regulation of cell projection organization GO:0031344 121 50 2,000 2,946E-03 0,02222098 ! regulation of ossification GO:0030278 117 50 2,000 2,946E-03 0,02215154 ! negative regulation of immune system process GO:0002683 95 50 2,000 2,946E-03 0,02208253 ! positive regulation of binding GO:0051099 78 51 2,000 3,117E-03 0,02329259 ! regulation of skeletal muscle tissue development GO:0048641 35 15 1,000 3,242E-03 0,02415283 ! ER-associated protein catabolic process GO:0030433 24 15 1,000 3,242E-03 0,02407829 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! negative regulation of bone remodeling GO:0046851 33 15 1,000 3,242E-03 0,0240042 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 1,000 3,242E-03 0,02393057 ! regulation of T-helper cell differentiation GO:0045622 26 15 1,000 3,242E-03 0,02385739 ! regulation of ATPase activity GO:0043462 21 15 1,000 3,242E-03 0,02378465 ! activation of phospholipase C activity GO:0007202 103 54 2,000 3,667E-03 0,02681575 GO:0010863|positive regulation of phospholipase C activity, ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 1,000 3,692E-03 0,02691663 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 1,000 3,692E-03 0,02683531 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 1,000 3,692E-03 0,02675448 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 1,000 3,692E-03 0,02667414 ! negative regulation of tissue remodeling GO:0034104 36 16 1,000 3,692E-03 0,02659428 ! defense response to virus GO:0051607 37 16 1,000 3,692E-03 0,02651489 ! positive regulation of phospholipase activity GO:0010518 104 55 2,000 3,862E-03 0,02765659 ! aging GO:0007568 103 55 2,000 3,862E-03 0,02757452 ! nucleotide-excision repair GO:0006289 83 56 2,000 4,064E-03 0,02892855 ! regulation of DNA replication GO:0006275 101 56 2,000 4,064E-03 0,02884322 ! negative regulation of hormone secretion GO:0046888 25 17 1,000 4,168E-03 0,02949757 ! limbic system development GO:0021761 36 17 1,000 4,168E-03 0,02941107 ! negative regulation of cell cycle process GO:0010948 32 17 1,000 4,168E-03 0,02932507 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 1,000 4,168E-03 0,02923957 ! regulation of striated muscle contraction GO:0006942 21 17 1,000 4,168E-03 0,02915458 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 1,000 4,168E-03 0,02907007 ! DNA unwinding during replication GO:0006268 27 17 1,000 4,168E-03 0,02898605 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 1,000 4,168E-03 0,02890252 ! negative regulation of homeostatic process GO:0032845 33 17 1,000 4,168E-03 0,02881947 ! regulation of phospholipase activity GO:0010517 106 57 2,000 4,272E-03 0,02945051 ! regulation of intracellular transport GO:0032386 101 57 2,000 4,272E-03 0,02936637 ! positive regulation of lipase activity GO:0060193 108 58 2,000 4,486E-03 0,03075181 ! positive regulation of anti-apoptosis GO:0045768 39 18 1,000 4,672E-03 0,03193365 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 4,672E-03 0,03184319 ! centrosome cycle GO:0007098 25 18 1,000 4,672E-03 0,03175324 ! response to retinoic acid GO:0032526 26 18 1,000 4,672E-03 0,03166379 ! cell-substrate junction assembly GO:0007044 54 18 1,000 4,672E-03 0,03157485 ! peptidyl-serine phosphorylation GO:0018105 38 18 1,000 4,672E-03 0,0314864 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 1,000 4,672E-03 0,03139845 ! regulation of immunoglobulin production GO:0002637 43 18 1,000 4,672E-03 0,03131099 ! nerve development GO:0021675 28 18 1,000 4,672E-03 0,03122402 ! positive regulation of synaptic transmission GO:0050806 28 18 1,000 4,672E-03 0,03113752 ! skeletal system morphogenesis GO:0048705 105 59 2,000 4,707E-03 0,03128442 ! DNA damage response, signal transduction GO:0042770 128 60 2,000 4,934E-03 0,03270406 ! negative regulation of response to stimulus GO:0048585 100 60 2,000 4,934E-03 0,03261421 ! response to peptide hormone stimulus GO:0043434 122 61 2,000 5,168E-03 0,03406537 ! positive regulation of translation GO:0045727 30 19 1,000 5,202E-03 0,03419709 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 1,000 5,202E-03 0,03410391 ! lipid phosphorylation GO:0046834 35 19 1,000 5,202E-03 0,03401124 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 1,000 5,202E-03 0,03391907 ! response to vitamin A GO:0033189 27 19 1,000 5,202E-03 0,0338274 ! actin filament bundle formation GO:0051017 42 19 1,000 5,202E-03 0,03373622 ! neuromuscular junction development GO:0007528 34 19 1,000 5,202E-03 0,03364553 ! regulation of endothelial cell migration GO:0010594 44 19 1,000 5,202E-03 0,03355533 ! G1 phase GO:0051318 40 19 1,000 5,202E-03 0,03346561 ! cell-cell junction organization GO:0045216 35 19 1,000 5,202E-03 0,03337636 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 1,000 5,202E-03 0,0332876 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 1,000 5,202E-03 0,0331993 ! peptide hormone secretion GO:0030072 31 19 1,000 5,202E-03 0,03311147 ! gonad development GO:0008406 98 62 2,000 5,408E-03 0,03433228 ! protein amino acid acetylation GO:0006473 39 20 1,000 5,758E-03 0,03646022 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 1,000 5,758E-03 0,03636452 ! response to vitamin GO:0033273 31 20 1,000 5,758E-03 0,03626933 ! apoptotic mitochondrial changes GO:0008637 41 20 1,000 5,758E-03 0,03617463 ! DNA duplex unwinding GO:0032508 31 20 1,000 5,758E-03 0,03608042 GO:0032392|DNA geometric change, ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 1,000 5,758E-03 0,03598671 ! peptide secretion GO:0002790 35 20 1,000 5,758E-03 0,03589348 ! stem cell differentiation GO:0048863 53 20 1,000 5,758E-03 0,03580073 ! negative regulation of angiogenesis GO:0016525 45 20 1,000 5,758E-03 0,03570846 ! peptidyl-serine modification GO:0018209 43 20 1,000 5,758E-03 0,03561667 ! positive regulation of neurological system process GO:0031646 32 20 1,000 5,758E-03 0,03552534 ! reciprocal meiotic recombination GO:0007131 39 21 1,000 6,341E-03 0,03901824 ! hormone secretion GO:0046879 38 21 1,000 6,341E-03 0,0389187 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 1,000 6,341E-03 0,03881967 ! axis specification GO:0009798 38 21 1,000 6,341E-03 0,03872114 ! cell structure disassembly during apoptosis GO:0006921 30 21 1,000 6,341E-03 0,03862311 ! cell aging GO:0007569 44 21 1,000 6,341E-03 0,03852558 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 1,000 6,341E-03 0,03842854 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 1,000 6,341E-03 0,03833199 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 1,000 6,341E-03 0,03823592 ! cholesterol biosynthetic process GO:0006695 37 21 1,000 6,341E-03 0,03814033 ! oogenesis GO:0048477 36 21 1,000 6,341E-03 0,03804521 ! negative regulation of intracellular transport GO:0032387 41 21 1,000 6,341E-03 0,03795057 ! lung development GO:0030324 144 67 2,000 6,71E-03 0,04005762 ! homeostasis of number of cells GO:0048872 114 67 2,000 6,71E-03 0,03995847 ! positive regulation of protein catabolic process GO:0045732 38 22 1,000 6,949E-03 0,0412818 ! glutamate signaling pathway GO:0007215 41 22 1,000 6,949E-03 0,04118012 ! calcium-independent cell-cell adhesion GO:0016338 30 22 1,000 6,949E-03 0,04107894 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 1,000 6,949E-03 0,04097826 ! apoptotic nuclear changes GO:0030262 32 22 1,000 6,949E-03 0,04087807 ! positive regulation of intracellular transport GO:0032388 37 22 1,000 6,949E-03 0,04077836 ! response to glucocorticoid stimulus GO:0051384 38 22 1,000 6,949E-03 0,04067915 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 1,000 6,949E-03 0,04058041 ! negative regulation of ligase activity GO:0051352 112 68 2,000 6,99E-03 0,04072255 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! regulation of lipase activity GO:0060191 130 68 2,000 6,99E-03 0,04062419 ! protein maturation by peptide bond cleavage GO:0051605 105 68 2,000 6,99E-03 0,0405263 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 2,000 6,99E-03 0,04042888 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 2,000 7,278E-03 0,04199078 ! respiratory tube development GO:0030323 150 70 2,000 7,572E-03 0,04358502 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 7,582E-03 0,0435397 ! regulation of anti-apoptosis GO:0045767 53 23 1,000 7,582E-03 0,04343604 ! regulation of cell-matrix adhesion GO:0001952 78 23 1,000 7,582E-03 0,04333287 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 48 23 1,000 7,582E-03 0,04323018 ! vesicle targeting GO:0006903 43 23 1,000 7,582E-03 0,04312798 ! sex determination GO:0007530 47 23 1,000 7,582E-03 0,04302627 ! regulation of interleukin-6 production GO:0032675 29 23 1,000 7,582E-03 0,04292503 ! hormone transport GO:0009914 40 23 1,000 7,582E-03 0,04282426 ! acetyl-CoA catabolic process GO:0046356 36 23 1,000 7,582E-03 0,04272397 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 1,000 7,582E-03 0,04262415 ! reproductive structure development GO:0048608 113 71 2,000 7,874E-03 0,0441577 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 2,000 8,182E-03 0,04578045 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 2,000 8,182E-03 0,04567423 ! respiratory system development GO:0060541 153 72 2,000 8,182E-03 0,0455685 ! positive regulation of fibroblast proliferation GO:0048146 43 24 1,000 8,241E-03 0,0457908 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 1,000 8,241E-03 0,04568529 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 1,000 8,241E-03 0,04558027 ! response to corticosteroid stimulus GO:0031960 41 24 1,000 8,241E-03 0,04547573 ! regulation of alpha-beta T cell activation GO:0046634 42 24 1,000 8,241E-03 0,04537166 ! pallium development GO:0021543 49 24 1,000 8,241E-03 0,04526807 ! regulation of oxidoreductase activity GO:0051341 46 24 1,000 8,241E-03 0,04516496 ! leukocyte homeostasis GO:0001776 44 24 1,000 8,241E-03 0,04506231 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 1,000 8,924E-03 0,04868762 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 1,000 8,924E-03 0,04857747 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 1,000 8,924E-03 0,04846781 ! negative regulation of DNA replication GO:0008156 42 25 1,000 8,924E-03 0,04835865 ! osteoblast differentiation GO:0001649 60 25 1,000 8,924E-03 0,04824998 ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 8,924E-03 0,04814179 ! coenzyme catabolic process GO:0009109 39 25 1,000 8,924E-03 0,04803409 ! negative regulation of cell development GO:0010721 73 25 1,000 8,924E-03 0,04792687 GO:0050768|negative regulation of neurogenesis, ! interaction with host GO:0051701 62 25 1,000 8,924E-03 0,04782013 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 1,000 8,924E-03 0,04771387 ! somitogenesis GO:0001756 43 25 1,000 8,924E-03 0,04760807 ! positive regulation of protein secretion GO:0050714 36 25 1,000 8,924E-03 0,04750274 ! cell-matrix adhesion GO:0007160 163 75 2,000 9,149E-03 0,04859418 ! development of primary sexual characteristics GO:0045137 124 76 2,000 9,486E-03 0,05027136 ! embryonic pattern specification GO:0009880 44 26 1,000 9,632E-03 0,05093161 ! initiation of viral infection GO:0019059 57 26 1,000 9,632E-03 0,05081992 ! acetyl-CoA metabolic process GO:0006084 39 26 1,000 9,632E-03 0,05070871 ! microtubule organizing center organization GO:0031023 39 26 1,000 9,632E-03 0,050598 GO:0051297|centrosome organization, ! regulation of endothelial cell proliferation GO:0001936 57 26 1,000 9,632E-03 0,05048776 ! positive regulation of MAPKKK cascade GO:0043410 47 26 1,000 9,632E-03 0,050378 ! positive regulation of nuclear division GO:0051785 40 26 1,000 9,632E-03 0,05026872 GO:0045840|positive regulation of mitosis, ! positive regulation of ligase activity GO:0051351 124 77 2,000 9,83E-03 0,05119145 ! positive regulation of lymphocyte activation GO:0051251 127 77 2,000 9,83E-03 0,05108088 ! blood coagulation GO:0007596 146 78 2,000 0,01018079 0,0527909 GO:0050817|coagulation, ! response to steroid hormone stimulus GO:0048545 137 78 2,000 0,01018079 0,05267737 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 1,000 0,01036352 0,05350778 ! protein amino acid acylation GO:0043543 55 27 1,000 0,01036352 0,0533932 ! regulation of fibroblast proliferation GO:0048145 52 27 1,000 0,01036352 0,05327911 ! base-excision repair GO:0006284 41 27 1,000 0,01036352 0,05316551 ! regulation of chromosome organization GO:0033044 42 27 1,000 0,01036352 0,0530524 ! negative regulation of neuron differentiation GO:0045665 42 27 1,000 0,01036352 0,05293976 ! activation of protein kinase activity GO:0032147 147 79 2,000 0,01053901 0,05372216 ! regulation of synaptic transmission GO:0050804 134 79 2,000 0,01053901 0,05360858 ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 0,01111919 0,05644042 ! positive regulation of T cell differentiation GO:0045582 42 28 1,000 0,01111919 0,0563216 ! response to hypoxia GO:0001666 171 81 2,000 0,01127719 0,05700192 ! cell-substrate adhesion GO:0031589 171 81 2,000 0,01127719 0,05688241 ! response to drug GO:0042493 143 82 2,000 0,01165719 0,05867616 ! response to nutrient GO:0007584 125 82 2,000 0,01165719 0,05855366 ! cellular response to hormone stimulus GO:0032870 167 82 2,000 0,01165719 0,05843167 ! cellular iron ion homeostasis GO:0006879 51 29 1,000 0,01189841 0,0595168 ! regulation of production of molecular mediator of immune response GO:0002700 61 29 1,000 0,01189841 0,05939332 ! response to organic cyclic substance GO:0014070 55 29 1,000 0,01189841 0,05927035 ! sterol biosynthetic process GO:0016126 52 29 1,000 0,01189841 0,05914789 ! cellular response to extracellular stimulus GO:0031668 48 29 1,000 0,01189841 0,05902594 ! tissue homeostasis GO:0001894 48 29 1,000 0,01189841 0,05890449 GO:0048871|multicellular organismal homeostasis, ! response to oxygen levels GO:0070482 176 83 2,000 0,01204451 0,0595053 ! hemostasis GO:0007599 158 84 2,000 0,01243915 0,06132908 ! regulation of transmission of nerve impulse GO:0051969 141 84 2,000 0,01243915 0,06120366 ! acute-phase response GO:0006953 49 30 1,000 0,01270091 0,06236406 ! cofactor catabolic process GO:0051187 51 30 1,000 0,01270091 0,06223704 ! positive regulation of cell activation GO:0050867 145 85 2,000 0,01284114 0,06279632 GO:0002696|positive regulation of leukocyte activation, ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 1,000 0,01352639 0,06601316 ! positive regulation of T cell proliferation GO:0042102 52 31 1,000 0,01352639 0,06587953 ! iron ion homeostasis GO:0055072 54 31 1,000 0,01352639 0,06574644 ! erythrocyte differentiation GO:0030218 55 31 1,000 0,01352639 0,06561389 ! regulation of neurological system process GO:0031644 148 88 2,000 0,01409142 0,0682172 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 1,000 0,01437456 0,06944818 ! spindle organization GO:0007051 46 32 1,000 0,01437456 0,06930901 ! response to ionizing radiation GO:0010212 65 32 1,000 0,01437456 0,06917039 ! peripheral nervous system development GO:0007422 64 32 1,000 0,01437456 0,06903233 ! BMP signaling pathway GO:0030509 64 32 1,000 0,01437456 0,06889481 ! hindbrain development GO:0030902 61 32 1,000 0,01437456 0,06875784 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 1,000 0,01437456 0,06862142 ! positive regulation of catabolic process GO:0009896 64 32 1,000 0,01437456 0,06848553 ! regulation of cell adhesion GO:0030155 212 89 2,000 0,014523 0,06905598 ! sex differentiation GO:0007548 145 90 2,000 0,01496201 0,07100316 ! DNA damage checkpoint GO:0000077 71 33 1,000 0,01524515 0,07220439 ! negative regulation of protein transport GO:0051224 69 33 1,000 0,01524515 0,07206253 ! establishment of vesicle localization GO:0051650 61 33 1,000 0,01524515 0,07192123 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 1,000 0,01613787 0,07598378 ! regulation of striated muscle tissue development GO:0016202 69 34 1,000 0,01613787 0,07583538 ! mesoderm morphogenesis GO:0048332 76 34 1,000 0,01613787 0,07568755 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 1,000 0,01613787 0,0755403 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 2,000 0,01632381 0,07626232 GO:0010498|proteasomal protein catabolic process, ! positive regulation of MAP kinase activity GO:0043406 160 93 2,000 0,01632381 0,07611452 ! negative regulation of multicellular organismal process GO:0051241 166 93 2,000 0,01632381 0,0759673 ! regulation of muscle development GO:0048634 70 35 1,000 0,01705244 0,07920498 ! negative regulation of secretion GO:0051048 63 35 1,000 0,01705244 0,07905237 ! negative regulation of DNA metabolic process GO:0051053 61 35 1,000 0,01705244 0,07890034 ! negative regulation of cell adhesion GO:0007162 81 35 1,000 0,01705244 0,0787489 ! embryonic skeletal system morphogenesis GO:0048704 59 35 1,000 0,01705244 0,07859804 ! female gonad development GO:0008585 58 35 1,000 0,01705244 0,07844776 ! telencephalon development GO:0021537 68 35 1,000 0,01705244 0,07829805 ! calcium-mediated signaling GO:0019722 62 35 1,000 0,01705244 0,07814891 ! vesicle localization GO:0051648 64 35 1,000 0,01705244 0,07800034 ! leukocyte differentiation GO:0002521 202 96 2,000 0,01775299 0,08105064 ! mitotic sister chromatid segregation GO:0000070 57 36 1,000 0,0179886 0,08197076 ! positive regulation of JAK-STAT cascade GO:0046427 50 36 1,000 0,0179886 0,08181581 ! DNA integrity checkpoint GO:0031570 75 36 1,000 0,0179886 0,08166144 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 1,000 0,0179886 0,08150765 ! aerobic respiration GO:0009060 55 36 1,000 0,0179886 0,08135444 ! protein ubiquitination GO:0016567 217 97 2,000 0,01824439 0,0823565 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 1,000 0,01894606 0,08536369 ! sister chromatid segregation GO:0000819 58 37 1,000 0,01894606 0,08520413 ! tissue remodeling GO:0048771 76 37 1,000 0,01894606 0,08504517 ! regulation of protein stability GO:0031647 73 37 1,000 0,01894606 0,0848868 ! glycogen metabolic process GO:0005977 61 37 1,000 0,01894606 0,08472901 ! positive regulation of DNA metabolic process GO:0051054 72 38 1,000 0,01992455 0,08893964 ! mitotic cell cycle checkpoint GO:0007093 76 38 1,000 0,01992455 0,08877493 ! development of primary female sexual characteristics GO:0046545 67 38 1,000 0,01992455 0,08861084 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 1,000 0,01992455 0,08844735 ! erythrocyte homeostasis GO:0034101 64 38 1,000 0,01992455 0,08828446 ! glucan metabolic process GO:0044042 62 38 1,000 0,01992455 0,08812218 GO:0006073|cellular glucan metabolic process, ! learning GO:0007612 77 39 1,000 0,02092381 0,09237189 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 1,000 0,02194357 0,09669638 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 1,000 0,02298356 0,10109406 ! female gamete generation GO:0007292 61 41 1,000 0,02298356 0,10090958 ! dorsal/ventral pattern formation GO:0009953 68 41 1,000 0,02298356 0,10072578 ! regulation of protein secretion GO:0050708 71 42 1,000 0,02404353 0,10517953 ! regulation of myeloid cell differentiation GO:0045637 98 42 1,000 0,02404353 0,10498864 ! epithelial cell differentiation GO:0030855 79 43 1,000 0,02512322 0,10950446 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 1,000 0,02512322 0,10930644 ! energy reserve metabolic process GO:0006112 74 43 1,000 0,02512322 0,10910914 ! glucose transport GO:0015758 65 43 1,000 0,02512322 0,10891254 ! striated muscle cell differentiation GO:0051146 82 43 1,000 0,02512322 0,10871666 ! hexose transport GO:0008645 67 44 1,000 0,02622236 0,1132693 GO:0015749|monosaccharide transport, ! male sex differentiation GO:0046661 76 44 1,000 0,02622236 0,11306631 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 1,000 0,02622236 0,11286404 ! developmental growth GO:0048589 82 44 1,000 0,02622236 0,1126625 ! maintenance of location in cell GO:0051651 97 44 1,000 0,02622236 0,11246168 ! glycolysis GO:0006096 65 45 1,000 0,02734071 0,11704937 ! regulation of JAK-STAT cascade GO:0046425 70 45 1,000 0,02734071 0,11684146 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,02823285 0,12044014 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,02823285 0,12022697 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,02823285 0,12001455 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,02823285 0,11980289 ! neuron fate determination GO:0048664 7 5 0,000 0,02823285 0,11959197 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02823285 0,11938179 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,02823285 0,11917235 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,02823285 0,11896364 ! polyol transport GO:0015791 12 5 0,000 0,02823285 0,11875566 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,02823285 0,11854841 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,02823285 0,11834188 ! response to superoxide GO:0000303 10 5 0,000 0,02823285 0,11813606 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,02823285 0,11793097 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,02823285 0,11772658 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,02823285 0,1175229 ! female meiosis GO:0007143 7 5 0,000 0,02823285 0,11731993 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,02823285 0,11711765 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,02823285 0,11691607 ! cobalt ion transport GO:0006824 11 5 0,000 0,02823285 0,11671518 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,02823285 0,11651499 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,02823285 0,11631547 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,02823285 0,11611664 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,02823285 0,11591849 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,02823285 0,11572102 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,02823285 0,11552421 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,02823285 0,11532808 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,02823285 0,1151326 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,02823285 0,11493779 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,02823285 0,11474364 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02823285 0,11455015 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,02823285 0,1143573 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 0,02823285 0,1141651 ! negative chemotaxis GO:0050919 14 5 0,000 0,02823285 0,11397355 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,02823285 0,11378264 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,02823285 0,11359237 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,02823285 0,11340273 ! behavioral response to pain GO:0048266 9 5 0,000 0,02823285 0,11321373 ! clathrin coat assembly GO:0048268 14 5 0,000 0,02823285 0,11302535 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02823285 0,1128376 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! micturition GO:0060073 9 5 0,000 0,02823285 0,11265048 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,02823285 0,11246397 ! copulation GO:0007620 9 5 0,000 0,02823285 0,11227808 ! glial cell fate commitment GO:0021781 13 5 0,000 0,02823285 0,1120928 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,02823285 0,11190813 ! spermidine metabolic process GO:0008216 7 5 0,000 0,02823285 0,11172407 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,02823285 0,11154062 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,02823285 0,11135777 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,02823285 0,11117551 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,02823285 0,11099385 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,02823285 0,11081278 ! grooming behavior GO:0007625 6 5 0,000 0,02823285 0,11063231 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,02823285 0,11045242 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,02823285 0,11027311 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02823285 0,11009439 ! positive regulation of glycolysis GO:0045821 14 5 0,000 0,02823285 0,10991624 ! lymph vessel development GO:0001945 10 5 0,000 0,02823285 0,10973867 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,02823285 0,10956167 ! endochondral ossification GO:0001958 16 5 0,000 0,02823285 0,10938524 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,02823285 0,10920938 ! parathyroid gland development GO:0060017 13 5 0,000 0,02823285 0,10903409 ! anagen GO:0042640 6 5 0,000 0,02823285 0,10885935 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,02823285 0,10868518 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,02823285 0,10851156 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,02823285 0,1083385 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,02823285 0,10816598 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,02823285 0,10799402 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,02823285 0,1078226 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,02823285 0,10765172 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,02823285 0,10748139 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,02823285 0,10731159 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,02823285 0,10714233 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,02823285 0,1069736 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,02823285 0,1068054 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,02823285 0,10663773 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,02823285 0,10647059 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,02823285 0,10630397 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,02823285 0,10613787 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 0,02823285 0,10597229 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,02823285 0,10580722 ! histidine catabolic process GO:0006548 6 5 0,000 0,02823285 0,10564267 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,02823285 0,10547863 ! valine metabolic process GO:0006573 10 5 0,000 0,02823285 0,1053151 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,02823285 0,10515207 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,02823285 0,10498955 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,02823285 0,10482753 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,02823285 0,104666 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,02823285 0,10450498 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,02823285 0,10434445 ! polyol catabolic process GO:0046174 7 5 0,000 0,02823285 0,10418441 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,02823285 0,10402486 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,02823285 0,10386581 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,02823285 0,10370723 ! muscle cell migration GO:0014812 8 5 0,000 0,02823285 0,10354914 ! mitochondrial fission GO:0000266 8 5 0,000 0,02823285 0,10339153 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,02823285 0,1032344 ! mRNA transcription GO:0009299 9 5 0,000 0,02823285 0,10307775 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,02823285 0,10292157 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,02823285 0,10276586 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,02823285 0,10261063 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,02823285 0,10245586 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,02823285 0,10230156 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,02823285 0,10214772 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,02823285 0,10199435 ! response to food GO:0032094 6 5 0,000 0,02823285 0,10184143 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,02823285 0,10168898 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,02823285 0,10153698 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02823285 0,10138543 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,02823285 0,10123433 ! forebrain neuron development GO:0021884 13 5 0,000 0,02823285 0,10108369 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,02823285 0,10093349 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,02823285 0,10078373 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,02823285 0,10063442 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02823285 0,10048556 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,02823285 0,10033713 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,02823285 0,10018914 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02823285 0,10004159 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,02823285 0,09989447 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,02823285 0,09974778 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,02823285 0,09960152 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,02823285 0,09945569 ! basic amino acid transport GO:0015802 11 5 0,000 0,02823285 0,09931029 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,02823285 0,09916531 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,02823285 0,09902075 ! depyrimidination GO:0045008 10 5 0,000 0,02823285 0,09887662 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02823285 0,0987329 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,02823285 0,0985896 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,02823285 0,09844672 GO:0006882|cellular zinc ion homeostasis, ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,02823285 0,09830425 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02823285 0,09816219 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,02823285 0,09802054 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,02823285 0,0978793 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,02823285 0,09773847 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,02823285 0,09759804 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,02823285 0,09745802 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02823285 0,09731839 ! response to arsenic GO:0046685 10 5 0,000 0,02823285 0,09717917 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,02823285 0,09704034 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,02823285 0,09690191 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,02823285 0,09676387 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,02823285 0,09662623 ! response to cadmium ion GO:0046686 7 5 0,000 0,02823285 0,09648897 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,02823285 0,09635211 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,02823285 0,09621563 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,02823285 0,09607954 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,02823285 0,09594384 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,02823285 0,09580851 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,02823285 0,09567357 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,02823285 0,09553901 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,02823285 0,09540483 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,02823285 0,09527102 ! neural tube patterning GO:0021532 7 5 0,000 0,02823285 0,09513759 ! embryonic cleavage GO:0040016 6 5 0,000 0,02823285 0,09500453 ! peroxisome fission GO:0016559 5 5 0,000 0,02823285 0,09487184 ! histone demethylation GO:0016577 10 5 0,000 0,02823285 0,09473952 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,02823285 0,09460757 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,02823285 0,09447599 ! metaphase plate congression GO:0051310 7 5 0,000 0,02823285 0,09434477 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02823285 0,09421392 GO:0032374|regulation of cholesterol transport, ! enteric nervous system development GO:0048484 8 5 0,000 0,02823285 0,09408343 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,02823285 0,0939533 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,02823285 0,09382353 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,02823285 0,09369412 ! muscle cell proliferation GO:0033002 11 5 0,000 0,02823285 0,09356506 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,02823285 0,09343636 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,02823285 0,09330802 ! plasminogen activation GO:0031639 5 5 0,000 0,02823285 0,09318002 ! B cell homeostasis GO:0001782 13 5 0,000 0,02823285 0,09305238 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,02823285 0,09292508 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,02823285 0,09279814 ! metaphase GO:0051323 8 5 0,000 0,02823285 0,09267154 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,02823285 0,09254528 ! cellular response to nutrient GO:0031670 8 5 0,000 0,02823285 0,09241937 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,02823285 0,0922938 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,02823285 0,09216857 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,02823285 0,09204368 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,02823285 0,09191913 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,02823285 0,09179491 ! response to redox state GO:0051775 5 5 0,000 0,02823285 0,09167103 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,02823285 0,09154749 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,02823285 0,09142428 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,02823285 0,09130139 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,02823285 0,09117884 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02823285 0,09105662 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,02823285 0,09093472 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02823285 0,09081315 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,02823285 0,0906919 ! striatum development GO:0021756 9 5 0,000 0,02823285 0,09057098 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,02823285 0,09045038 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,02823285 0,0903301 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,02823285 0,09021014 ! glial cell migration GO:0008347 11 5 0,000 0,02823285 0,0900905 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,02823285 0,08997117 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,02823285 0,08985216 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,02823285 0,08973347 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,02823285 0,08961509 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,02823285 0,08949702 ! neuroprotection GO:0043526 6 5 0,000 0,02823285 0,08937926 ! neural plate development GO:0001840 8 5 0,000 0,02823285 0,08926181 ! regulation of sensory perception GO:0051931 7 5 0,000 0,02823285 0,08914467 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,02823285 0,08902783 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,02823285 0,0889113 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,02823285 0,08879508 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,02823285 0,08867916 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,02823285 0,08856354 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,02823285 0,08844822 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,02823285 0,08833321 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,02823285 0,08821849 ! spindle assembly GO:0051225 6 5 0,000 0,02823285 0,08810407 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,02823285 0,08798994 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,02823285 0,08787611 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,02823285 0,08776258 ! drug metabolic process GO:0017144 6 5 0,000 0,02823285 0,08764934 ! phospholipid scrambling GO:0017121 8 5 0,000 0,02823285 0,08753639 ! organ regeneration GO:0031100 7 5 0,000 0,02823285 0,08742373 ! carnitine metabolic process GO:0009437 7 5 0,000 0,02823285 0,08731136 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,02823285 0,08719928 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,02823285 0,08708748 ! negative regulation of cell migration GO:0030336 115 46 1,000 0,02847801 0,08773122 ! vascular process in circulatory system GO:0003018 80 47 1,000 0,02963401 0,09117572 ! regulation of adaptive immune response GO:0002819 84 47 1,000 0,02963401 0,09105928 ! JNK cascade GO:0007254 91 47 1,000 0,02963401 0,09094313 ! protein homooligomerization GO:0051260 76 47 1,000 0,02963401 0,09082728 ! cellular component disassembly GO:0022411 86 48 1,000 0,03080846 0,0943068 ! activation of caspase activity GO:0006919 84 48 1,000 0,03080846 0,09418697 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 1,000 0,03200112 0,09770899 ! endocrine system development GO:0035270 104 49 1,000 0,03200112 0,09758515 ! histone modification GO:0016570 91 50 1,000 0,03321174 0,10114866 ! positive regulation of cytokine production GO:0001819 86 50 1,000 0,03321174 0,10102079 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,03378359 0,10263046 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,03378359 0,10250104 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,03378359 0,10237194 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,03378359 0,10224317 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,03378359 0,10211473 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,03378359 0,1019866 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,03378359 0,1018588 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,03378359 0,10173132 ! sleep GO:0030431 13 6 0,000 0,03378359 0,10160415 ! response to oxygen radical GO:0000305 11 6 0,000 0,03378359 0,10147731 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,03378359 0,10135078 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,03378359 0,10122456 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,03378359 0,10109866 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,03378359 0,10097307 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,03378359 0,10084779 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,03378359 0,10072283 ! forebrain regionalization GO:0021871 8 6 0,000 0,03378359 0,10059817 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,03378359 0,10047382 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,03378359 0,10034978 ! response to zinc ion GO:0010043 9 6 0,000 0,03378359 0,10022605 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,03378359 0,10010261 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,03378359 0,09997949 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,03378359 0,09985666 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,03378359 0,09973414 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,03378359 0,09961191 ! malate metabolic process GO:0006108 11 6 0,000 0,03378359 0,09948999 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,03378359 0,09936836 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,03378359 0,09924704 ! protein refolding GO:0042026 15 6 0,000 0,03378359 0,099126 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,03378359 0,09900526 ! opsonization GO:0008228 8 6 0,000 0,03378359 0,09888482 ! mating behavior GO:0007617 7 6 0,000 0,03378359 0,09876467 ! neuron remodeling GO:0016322 15 6 0,000 0,03378359 0,09864481 ! erythrocyte maturation GO:0043249 7 6 0,000 0,03378359 0,09852524 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,03378359 0,09840596 ! equilibrioception GO:0050957 14 6 0,000 0,03378359 0,09828697 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,03378359 0,09816826 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,03378359 0,09804985 ! photoreceptor cell development GO:0042461 10 6 0,000 0,03378359 0,09793171 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,03378359 0,09781387 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,03378359 0,0976963 ! response to interferon-gamma GO:0034341 15 6 0,000 0,03378359 0,09757902 ! toxin metabolic process GO:0009404 11 6 0,000 0,03378359 0,09746202 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,03378359 0,0973453 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,03378359 0,09722885 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,03378359 0,09711269 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,03378359 0,0969968 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,03378359 0,09688119 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,03378359 0,09676586 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,03378359 0,0966508 ! thymic T cell selection GO:0045061 12 6 0,000 0,03378359 0,09653601 ! protein lipoylation GO:0009249 10 6 0,000 0,03378359 0,0964215 ! cysteine metabolic process GO:0006534 10 6 0,000 0,03378359 0,09630725 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,03378359 0,09619328 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,03378359 0,09607958 ! glutamate catabolic process GO:0006538 10 6 0,000 0,03378359 0,09596614 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,03378359 0,09585297 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,03378359 0,09574007 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,03378359 0,09562744 ! response to pH GO:0009268 10 6 0,000 0,03378359 0,09551507 ! hyperosmotic response GO:0006972 9 6 0,000 0,03378359 0,09540296 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,03378359 0,09529112 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,03378359 0,09517953 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,03378359 0,09506821 ! urea metabolic process GO:0019627 7 6 0,000 0,03378359 0,09495715 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,03378359 0,09484635 ! neutrophil activation GO:0042119 8 6 0,000 0,03378359 0,09473581 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,03378359 0,09462552 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,03378359 0,09451549 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,03378359 0,09440572 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,03378359 0,0942962 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,03378359 0,09418693 ! neuron apoptosis GO:0051402 9 6 0,000 0,03378359 0,09407792 ! nucleoside salvage GO:0043174 9 6 0,000 0,03378359 0,09396916 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,03378359 0,09386065 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,03378359 0,09375239 ! T cell mediated immunity GO:0002456 16 6 0,000 0,03378359 0,09364438 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,03378359 0,09353662 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 0,03378359 0,09342911 ! carnitine transport GO:0015879 10 6 0,000 0,03378359 0,09332184 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,03378359 0,09321482 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,03378359 0,09310804 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,03378359 0,09300151 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,03378359 0,09289523 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,03378359 0,09278918 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,03378359 0,09268338 ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,03378359 0,09257782 ! monocyte differentiation GO:0030224 12 6 0,000 0,03378359 0,09247249 ! astrocyte development GO:0014002 15 6 0,000 0,03378359 0,09236741 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,03378359 0,09226257 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,03378359 0,09215796 ! interaction with symbiont GO:0051702 13 6 0,000 0,03378359 0,09205359 ! regulation of dendrite development GO:0050773 16 6 0,000 0,03378359 0,09194946 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,03378359 0,09184556 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,03378359 0,0917419 ! response to copper ion GO:0046688 10 6 0,000 0,03378359 0,09163847 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,03378359 0,09153527 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,03378359 0,09143231 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,03378359 0,09132958 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,03378359 0,09122707 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,03378359 0,0911248 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,03378359 0,09102276 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,03378359 0,09092094 ! hair follicle maturation GO:0048820 7 6 0,000 0,03378359 0,09081935 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,03378359 0,09071799 ! Schwann cell development GO:0014044 15 6 0,000 0,03378359 0,09061686 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,03378359 0,09051595 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,03378359 0,09041526 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,03378359 0,0903148 ! subpallium development GO:0021544 10 6 0,000 0,03378359 0,09021456 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,03378359 0,09011455 ! histone ubiquitination GO:0016574 8 6 0,000 0,03378359 0,09001475 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,03378359 0,08991518 ! maintenance of organ identity GO:0048496 9 6 0,000 0,03378359 0,08981583 ! G2 phase GO:0051319 16 6 0,000 0,03378359 0,08971669 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,03378359 0,08961778 ! establishment of planar polarity GO:0001736 7 6 0,000 0,03378359 0,08951908 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,03378359 0,0894206 ! membrane to membrane docking GO:0022614 14 6 0,000 0,03378359 0,08932233 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,03378359 0,08922428 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,03378359 0,08912645 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,03378359 0,08902883 ! receptor internalization GO:0031623 10 6 0,000 0,03378359 0,08893143 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,03378359 0,08883423 GO:0043011|myeloid dendritic cell differentiation, ! protein deubiquitination GO:0016579 14 6 0,000 0,03378359 0,08873725 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 0,03378359 0,08864048 ! protein destabilization GO:0031648 9 6 0,000 0,03378359 0,08854392 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,03378359 0,08844758 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,03378359 0,08835144 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,03378359 0,08825551 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,03378359 0,08815979 ! progesterone metabolic process GO:0042448 10 6 0,000 0,03378359 0,08806427 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,03378359 0,08796896 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,03378359 0,08787386 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,03378359 0,08777897 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,03378359 0,08768427 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,03378359 0,08758979 ! determination of adult lifespan GO:0008340 15 6 0,000 0,03378359 0,0874955 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,03378359 0,08740142 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,03378359 0,08730754 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,03378359 0,08721387 ! catecholamine transport GO:0051937 9 6 0,000 0,03378359 0,08712039 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,03378359 0,08702711 ! sensory cilium assembly GO:0035058 10 6 0,000 0,03378359 0,08693403 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,03378359 0,08684116 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,03378359 0,08674848 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,03378359 0,08665599 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,03378359 0,08656371 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,03378359 0,08647162 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,03378359 0,08637973 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,03378359 0,08628803 ! viral infectious cycle GO:0019058 99 51 1,000 0,03444008 0,08787152 ! response to estrogen stimulus GO:0043627 93 51 1,000 0,03444008 0,08777843 ! embryonic skeletal system development GO:0048706 85 51 1,000 0,03444008 0,08768555 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 1,000 0,03444008 0,08759286 ! vesicle organization GO:0016050 107 51 1,000 0,03444008 0,08750036 ! regulation of cell shape GO:0008360 125 51 1,000 0,03444008 0,08740806 ! covalent chromatin modification GO:0016569 101 52 1,000 0,03568591 0,0904745 ! synapse organization GO:0050808 85 52 1,000 0,03568591 0,09037927 ! cell maturation GO:0048469 100 53 1,000 0,03694898 0,09347976 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 1,000 0,03822907 0,09661674 ! tRNA transcription GO:0009304 14 7 0,000 0,03930281 0,0992262 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,03930281 0,09912219 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,03930281 0,09901839 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,03930281 0,09891482 ! regulation of helicase activity GO:0051095 15 7 0,000 0,03930281 0,09881146 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,03930281 0,09870831 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,03930281 0,09860539 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,03930281 0,09850267 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,03930281 0,09840017 ! prostate gland development GO:0030850 13 7 0,000 0,03930281 0,09829788 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,03930281 0,09819581 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,03930281 0,09809395 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,03930281 0,0979923 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,03930281 0,09789085 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,03930281 0,09778962 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,03930281 0,0976886 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,03930281 0,09758779 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,03930281 0,09748718 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,03930281 0,09738678 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,03930281 0,09728659 ! glycolipid transport GO:0046836 10 7 0,000 0,03930281 0,0971866 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,03930281 0,09708682 GO:0051923|sulfation, ! neuron adhesion GO:0007158 12 7 0,000 0,03930281 0,09698725 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,03930281 0,09688787 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,03930281 0,09678871 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,03930281 0,09668974 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,03930281 0,09659098 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,03930281 0,09649241 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,03930281 0,09639405 ! pericardium development GO:0060039 14 7 0,000 0,03930281 0,09629589 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,03930281 0,09619793 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,03930281 0,09610017 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,03930281 0,0960026 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,03930281 0,09590524 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,03930281 0,09580807 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,03930281 0,0957111 ! lipoprotein transport GO:0042953 14 7 0,000 0,03930281 0,09561432 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,03930281 0,09551774 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,03930281 0,09542136 ! rhythmic behavior GO:0007622 15 7 0,000 0,03930281 0,09532517 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,03930281 0,09522917 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,03930281 0,09513337 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,03930281 0,09503775 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,03930281 0,09494233 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,03930281 0,09484711 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,03930281 0,09475207 ! mechanosensory behavior GO:0007638 14 7 0,000 0,03930281 0,09465722 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,03930281 0,09456256 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,03930281 0,0944681 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,03930281 0,09437382 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,03930281 0,09427973 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,03930281 0,09418582 ! spinal cord patterning GO:0021511 13 7 0,000 0,03930281 0,0940921 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,03930281 0,09399857 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,03930281 0,09390523 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,03930281 0,09381207 ! adrenal gland development GO:0030325 17 7 0,000 0,03930281 0,09371909 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,03930281 0,0936263 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,03930281 0,09353369 ! ovulation GO:0030728 9 7 0,000 0,03930281 0,09344127 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,03930281 0,09334903 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,03930281 0,09325697 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,03930281 0,09316509 ! microtubule nucleation GO:0007020 20 7 0,000 0,03930281 0,09307339 ! proline biosynthetic process GO:0006561 10 7 0,000 0,03930281 0,09298187 ! thyroid hormone generation GO:0006590 13 7 0,000 0,03930281 0,09289054 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,03930281 0,09279938 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,03930281 0,0927084 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,03930281 0,0926176 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,03930281 0,09252697 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,03930281 0,09243652 ! galactose metabolic process GO:0006012 13 7 0,000 0,03930281 0,09234625 ! response to dietary excess GO:0002021 8 7 0,000 0,03930281 0,09225616 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,03930281 0,09216624 ! intracellular pH reduction GO:0051452 11 7 0,000 0,03930281 0,0920765 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,03930281 0,09198693 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,03930281 0,09189754 ! organ growth GO:0035265 15 7 0,000 0,03930281 0,09180832 ! purine salvage GO:0043101 10 7 0,000 0,03930281 0,09171927 ! nucleoside transport GO:0015858 8 7 0,000 0,03930281 0,09163039 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,03930281 0,09154169 ! parturition GO:0007567 14 7 0,000 0,03930281 0,09145316 ! rRNA modification GO:0000154 14 7 0,000 0,03930281 0,0913648 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,03930281 0,09127661 ! spindle checkpoint GO:0031577 15 7 0,000 0,03930281 0,09118859 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,03930281 0,09110074 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,03930281 0,09101306 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,03930281 0,09092554 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,03930281 0,0908382 GO:0046676|negative regulation of insulin secretion, ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,03930281 0,09075102 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 0,03930281 0,09066401 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,03930281 0,09057717 ! fibrinolysis GO:0042730 10 7 0,000 0,03930281 0,09049049 ! eating behavior GO:0042755 7 7 0,000 0,03930281 0,09040398 ! B cell lineage commitment GO:0002326 21 7 0,000 0,03930281 0,09031764 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,03930281 0,09023146 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,03930281 0,09014544 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,03930281 0,09005959 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,03930281 0,0899739 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,03930281 0,08988837 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,03930281 0,08980301 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,03930281 0,0897178 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,03930281 0,08963276 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,03930281 0,08954788 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,03930281 0,08946316 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,03930281 0,08937861 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,03930281 0,08929421 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,03930281 0,08920997 ! regulation of meiosis GO:0040020 12 7 0,000 0,03930281 0,08912589 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,03930281 0,08904196 ! T cell lineage commitment GO:0002360 16 7 0,000 0,03930281 0,0889582 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,03930281 0,08887459 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,03930281 0,08879114 ! oxygen homeostasis GO:0032364 12 7 0,000 0,03930281 0,08870785 ! transcription termination GO:0006353 13 7 0,000 0,03930281 0,08862471 ! response to tumor cell GO:0002347 13 7 0,000 0,03930281 0,08854173 ! regulation of respiratory burst GO:0060263 11 7 0,000 0,03930281 0,0884589 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,03930281 0,08837623 ! anaphase GO:0051322 17 7 0,000 0,03930281 0,08829371 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,03930281 0,08821135 ! axonal fasciculation GO:0007413 18 7 0,000 0,03930281 0,08812914 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,03930281 0,08804708 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,03930281 0,08796518 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,03930281 0,08788342 ! diuresis GO:0030146 12 7 0,000 0,03930281 0,08780182 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,03930281 0,08772038 ! thiamin metabolic process GO:0006772 7 7 0,000 0,03930281 0,08763908 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,03930281 0,08755793 ! antibiotic transport GO:0042891 9 7 0,000 0,03930281 0,08747693 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,03930281 0,08739609 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,03930281 0,08731539 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,03930281 0,08723484 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,03930281 0,08715444 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,03930281 0,08707419 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,03930281 0,08699408 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,03930281 0,08691412 ! lymph node development GO:0048535 10 7 0,000 0,03930281 0,08683431 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,03930281 0,08675465 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,03930281 0,08667513 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,03930281 0,08659576 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,03930281 0,08651653 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,03930281 0,08643745 ! adult feeding behavior GO:0008343 9 7 0,000 0,03930281 0,08635851 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,03930281 0,08627971 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,03930281 0,08620106 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,03930281 0,08612255 ! muscle adaptation GO:0043500 14 7 0,000 0,03930281 0,08604419 ! embryonic heart tube development GO:0035050 10 7 0,000 0,03930281 0,08596597 ! retina homeostasis GO:0001895 12 7 0,000 0,03930281 0,08588789 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,03930281 0,08580995 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,03930281 0,08573215 ! protein prenylation GO:0018342 18 7 0,000 0,03930281 0,0856545 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,03930281 0,08557698 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,03930281 0,08549961 ! positive regulation of caspase activity GO:0043280 95 55 1,000 0,03952593 0,0859073 GO:0010952|positive regulation of peptidase activity, ! glucose catabolic process GO:0006007 82 55 1,000 0,03952593 0,08582977 ! cellular polysaccharide metabolic process GO:0044264 86 55 1,000 0,03952593 0,08575237 ! regulation of protein catabolic process GO:0042176 116 55 1,000 0,03952593 0,08567512 ! negative regulation of cell motion GO:0051271 134 55 1,000 0,03952593 0,085598 ! positive regulation of organelle organization GO:0010638 100 56 1,000 0,04083933 0,0883628 ! lipid modification GO:0030258 97 57 1,000 0,04216906 0,09115791 ! maintenance of location GO:0051235 118 57 1,000 0,04216906 0,09107608 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,04479069 0,09665147 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,04479069 0,09656487 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,04479069 0,09647842 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,04479069 0,09639212 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,04479069 0,09630598 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,04479069 0,09621999 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,04479069 0,09613416 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,04479069 0,09604848 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,04479069 0,09596295 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,04479069 0,09587757 ! meiotic prophase I GO:0007128 13 8 0,000 0,04479069 0,09579235 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,04479069 0,09570728 ! UTP metabolic process GO:0046051 8 8 0,000 0,04479069 0,09562235 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,04479069 0,09553758 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,04479069 0,09545296 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,04479069 0,09536849 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,04479069 0,09528417 ! succinate metabolic process GO:0006105 14 8 0,000 0,04479069 0,09519999 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,04479069 0,09511597 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,04479069 0,09503209 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,04479069 0,09494836 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,04479069 0,09486478 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,04479069 0,09478135 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,04479069 0,09469806 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,04479069 0,09461492 ! reflex GO:0060004 16 8 0,000 0,04479069 0,09453192 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,04479069 0,09444907 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,04479069 0,09436637 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,04479069 0,09428381 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,04479069 0,09420139 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,04479069 0,09411912 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,04479069 0,09403699 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,04479069 0,09395501 ! pigment granule organization GO:0048753 16 8 0,000 0,04479069 0,09387316 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,04479069 0,09379146 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,04479069 0,09370991 ! astrocyte differentiation GO:0048708 18 8 0,000 0,04479069 0,09362849 ! histidine metabolic process GO:0006547 16 8 0,000 0,04479069 0,09354722 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,04479069 0,09346608 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,04479069 0,09338509 ! glycine catabolic process GO:0006546 13 8 0,000 0,04479069 0,09330424 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,04479069 0,09322352 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,04479069 0,09314295 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,04479069 0,09306251 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,04479069 0,09298222 ! melanin metabolic process GO:0006582 15 8 0,000 0,04479069 0,09290206 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,04479069 0,09282204 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,04479069 0,09274216 ! macrophage activation GO:0042116 12 8 0,000 0,04479069 0,09266242 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,04479069 0,09258281 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,04479069 0,09250334 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,04479069 0,09242401 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,04479069 0,09234481 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,04479069 0,09226575 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,04479069 0,09218682 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,04479069 0,09210803 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,04479069 0,09202937 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,04479069 0,09195085 ! response to UV-B GO:0010224 16 8 0,000 0,04479069 0,09187246 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,04479069 0,0917942 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,04479069 0,09171608 ! intermediate filament organization GO:0045109 12 8 0,000 0,04479069 0,09163809 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,04479069 0,09156023 ! cellular extravasation GO:0045123 12 8 0,000 0,04479069 0,09148251 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,04479069 0,09140491 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,04479069 0,09132745 ! response to antibiotic GO:0046677 11 8 0,000 0,04479069 0,09125012 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,04479069 0,09117292 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,04479069 0,09109585 ! DNA topological change GO:0006265 12 8 0,000 0,04479069 0,09101891 ! response to tropane GO:0014073 15 8 0,000 0,04479069 0,0909421 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,04479069 0,09086542 ! melanosome transport GO:0032402 13 8 0,000 0,04479069 0,09078887 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,04479069 0,09071245 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,04479069 0,09063616 ! mast cell activation GO:0045576 14 8 0,000 0,04479069 0,09055999 ! multicellular organismal aging GO:0010259 18 8 0,000 0,04479069 0,09048396 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,04479069 0,09040805 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,04479069 0,09033227 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,04479069 0,09025661 ! nucleosome disassembly GO:0006337 14 8 0,000 0,04479069 0,09018108 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,04479069 0,09010568 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,04479069 0,0900304 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,04479069 0,08995525 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,04479069 0,08988023 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,04479069 0,08980533 ! intracellular lipid transport GO:0032365 13 8 0,000 0,04479069 0,08973055 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,04479069 0,0896559 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,04479069 0,08958137 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,04479069 0,08950697 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,04479069 0,08943269 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,04479069 0,08935853 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,04479069 0,0892845 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,04479069 0,08921059 ! hormone catabolic process GO:0042447 17 8 0,000 0,04479069 0,0891368 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,04479069 0,08906313 GO:0010828|positive regulation of glucose transport, ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,04479069 0,08898959 ! ATP catabolic process GO:0006200 11 8 0,000 0,04479069 0,08891617 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,04479069 0,08884286 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,04479069 0,08876968 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,04479069 0,08869662 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,04479069 0,08862368 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,04479069 0,08855086 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,04479069 0,08847815 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,04479069 0,08840557 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,04479069 0,08833311 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,04479069 0,08826076 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,04479069 0,08818854 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,04479069 0,08811643 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,04479069 0,08804444 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,04479069 0,08797257 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,04479069 0,08790081 GO:0000076|DNA replication checkpoint, ! NAD biosynthetic process GO:0009435 13 8 0,000 0,04479069 0,08782917 ! cytokine-mediated signaling pathway GO:0019221 97 59 1,000 0,04487655 0,08792589 ! DNA catabolic process GO:0006308 86 59 1,000 0,04487655 0,08785434 ! integrin-mediated signaling pathway GO:0007229 135 59 1,000 0,04487655 0,08778292 ! viral reproductive process GO:0022415 126 62 1,000 0,04905458 0,09587759 ! regulation of homeostatic process GO:0032844 134 62 1,000 0,04905458 0,09579976 ! axon extension GO:0048675 15 9 0,000 0,05024739 0,09804966 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,05024739 0,0979702 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,05024739 0,09789087 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,05024739 0,09781167 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,05024739 0,0977326 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,05024739 0,09765366 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,05024739 0,09757484 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,05024739 0,09749615 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,05024739 0,09741759 ! phosphate transport GO:0006817 19 9 0,000 0,05024739 0,09733915 ! reproductive behavior GO:0019098 19 9 0,000 0,05024739 0,09726084 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,05024739 0,09718266 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,05024739 0,0971046 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,05024739 0,09702667 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! GTP metabolic process GO:0046039 9 9 0,000 0,05024739 0,09694886 ! RNA methylation GO:0001510 15 9 0,000 0,05024739 0,09687118 ! elastic fiber assembly GO:0048251 15 9 0,000 0,05024739 0,09679362 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,05024739 0,09671618 ! artery development GO:0060840 24 9 0,000 0,05024739 0,09663887 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,05024739 0,09656169 ! regulation of glycolysis GO:0006110 21 9 0,000 0,05024739 0,09648462 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,05024739 0,09640768 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,05024739 0,09633086 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,05024739 0,09625416 ! chemosensory behavior GO:0007635 20 9 0,000 0,05024739 0,09617759 ! microtubule bundle formation GO:0001578 21 9 0,000 0,05024739 0,09610114 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,05024739 0,09602481 ! leukocyte degranulation GO:0043299 16 9 0,000 0,05024739 0,0959486 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,05024739 0,09587251 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,05024739 0,09579654 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,05024739 0,09572069 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,05024739 0,09564496 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,05024739 0,09556935 ! protein targeting to ER GO:0045047 22 9 0,000 0,05024739 0,09549386 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,05024739 0,09541849 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,05024739 0,09534324 ! T cell selection GO:0045058 23 9 0,000 0,05024739 0,09526811 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,05024739 0,09519309 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,05024739 0,0951182 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,05024739 0,09504342 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,05024739 0,09496876 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,05024739 0,09489422 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,05024739 0,09481979 ! mannose metabolic process GO:0006013 13 9 0,000 0,05024739 0,09474548 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,05024739 0,09467128 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,05024739 0,09459721 ! receptor clustering GO:0043113 18 9 0,000 0,05024739 0,09452324 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,05024739 0,0944494 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,05024739 0,09437567 ! ruffle organization GO:0031529 15 9 0,000 0,05024739 0,09430205 ! retinol metabolic process GO:0042572 18 9 0,000 0,05024739 0,09422855 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,05024739 0,09415516 ! behavioral fear response GO:0001662 22 9 0,000 0,05024739 0,09408189 GO:0002209|behavioral defense response, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,05024739 0,09400873 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,05024739 0,09393569 GO:0030204|chondroitin sulfate metabolic process, ! protein heterooligomerization GO:0051291 16 9 0,000 0,05024739 0,09386276 ! oligodendrocyte development GO:0014003 10 9 0,000 0,05024739 0,09378994 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,05024739 0,09371723 ! segment specification GO:0007379 13 9 0,000 0,05024739 0,09364464 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,05024739 0,09357216 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,05024739 0,09349979 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,05024739 0,09342753 ! response to amine stimulus GO:0014075 13 9 0,000 0,05024739 0,09335539 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,05024739 0,09328336 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,05024739 0,09321143 ! erythrocyte development GO:0048821 15 9 0,000 0,05024739 0,09313962 ! gas homeostasis GO:0033483 16 9 0,000 0,05024739 0,09306792 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,05024739 0,09299633 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,05024739 0,09292485 ! renal water homeostasis GO:0003091 14 9 0,000 0,05024739 0,09285348 ! postreplication repair GO:0006301 22 9 0,000 0,05024739 0,09278222 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,05024739 0,09271107 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,05024739 0,09264002 ! icosanoid secretion GO:0032309 15 9 0,000 0,05024739 0,09256909 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,05024739 0,09249826 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,05024739 0,09242755 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,05024739 0,09235694 ! regulation of cell division GO:0051302 15 9 0,000 0,05024739 0,09228644 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,05024739 0,09221604 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,05024739 0,09214575 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,05024739 0,09207558 ! sterol catabolic process GO:0016127 11 9 0,000 0,05024739 0,0920055 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,05024739 0,09193554 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,05024739 0,09186568 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,05024739 0,09179592 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,05024739 0,09172627 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,05024739 0,09165673 ! musculoskeletal movement GO:0050881 14 9 0,000 0,05024739 0,0915873 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,05024739 0,09151796 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,05024739 0,09144874 ! purine base metabolic process GO:0006144 21 9 0,000 0,05024739 0,09137961 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,05024739 0,0913106 ! pigment granule transport GO:0051904 17 9 0,000 0,05024739 0,09124168 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,05024739 0,09117287 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,05024739 0,09110417 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,05024739 0,09103556 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,05024739 0,09096707 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,05024739 0,09089867 ! mitochondrion localization GO:0051646 15 9 0,000 0,05024739 0,09083038 ! regulation of mitosis GO:0007088 105 63 1,000 0,05047751 0,09117785 GO:0051783|regulation of nuclear division, ! multicellular organism reproduction GO:0032504 111 64 1,000 0,05191522 0,09370444 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 1,000 0,05191522 0,0936342 ! regulation of cytokine biosynthetic process GO:0042035 95 65 1,000 0,05336749 0,09618141 ! germ cell development GO:0007281 118 65 1,000 0,05336749 0,09610941 ! actin filament organization GO:0007015 148 66 1,000 0,0548341 0,09867678 ! developmental maturation GO:0021700 116 66 1,000 0,0548341 0,09860303 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,05567311 0,10003697 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,05567311 0,09996231 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,05567311 0,09988777 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,05567311 0,09981334 ! synapsis GO:0007129 13 10 0,000 0,05567311 0,09973902 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,05567311 0,09966481 ! N-glycan processing GO:0006491 20 10 0,000 0,05567311 0,09959071 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,05567311 0,09951672 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,05567311 0,09944284 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,05567311 0,09936907 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,05567311 0,09929541 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,05567311 0,09922185 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,05567311 0,09914841 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,05567311 0,09907508 ! androgen metabolic process GO:0008209 17 10 0,000 0,05567311 0,09900185 ! phospholipid efflux GO:0033700 16 10 0,000 0,05567311 0,09892873 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,05567311 0,09885572 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,05567311 0,09878282 ! pathogenesis GO:0009405 13 10 0,000 0,05567311 0,09871002 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,05567311 0,09863734 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,05567311 0,09856476 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,05567311 0,09849228 ! endoderm development GO:0007492 16 10 0,000 0,05567311 0,09841991 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,05567311 0,09834765 ! arginine catabolic process GO:0006527 13 10 0,000 0,05567311 0,0982755 ! proline metabolic process GO:0006560 13 10 0,000 0,05567311 0,09820345 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,05567311 0,0981315 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,05567311 0,09805966 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,05567311 0,09798793 ! V(D)J recombination GO:0033151 28 10 0,000 0,05567311 0,0979163 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,05567311 0,09784478 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,05567311 0,09777336 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,05567311 0,09770204 ! B cell proliferation GO:0042100 18 10 0,000 0,05567311 0,09763083 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,05567311 0,09755972 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,05567311 0,09748872 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,05567311 0,09741782 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,05567311 0,09734702 ! epithelial cell development GO:0002064 20 10 0,000 0,05567311 0,09727633 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,05567311 0,09720573 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,05567311 0,09713524 ! macroautophagy GO:0016236 17 10 0,000 0,05567311 0,09706486 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,05567311 0,09699457 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,05567311 0,09692439 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,05567311 0,0968543 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,05567311 0,09678432 ! copper ion homeostasis GO:0055070 13 10 0,000 0,05567311 0,09671444 ! brain morphogenesis GO:0048854 23 10 0,000 0,05567311 0,09664466 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,05567311 0,09657498 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,05567311 0,0965054 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,05567311 0,09643593 ! response to dsRNA GO:0043331 20 10 0,000 0,05567311 0,09636655 ! DNA ligation GO:0006266 19 10 0,000 0,05567311 0,09629727 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,05567311 0,09622809 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,05567311 0,09615901 ! melanosome localization GO:0032400 16 10 0,000 0,05567311 0,09609003 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,05567311 0,09602115 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,05567311 0,09595237 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,05567311 0,09588368 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,05567311 0,09581509 ! mRNA cleavage GO:0006379 17 10 0,000 0,05567311 0,09574661 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,05567311 0,09567822 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,05567311 0,09560992 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,05567311 0,09554173 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,05567311 0,09547363 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,05567311 0,09540563 ! prophase GO:0051324 15 10 0,000 0,05567311 0,09533772 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,05567311 0,09526992 ! apical protein localization GO:0045176 15 10 0,000 0,05567311 0,0952022 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,05567311 0,09513459 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! midbrain development GO:0030901 13 10 0,000 0,05567311 0,09506707 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,05567311 0,09499965 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,05567311 0,09493232 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,05567311 0,09486509 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,05567311 0,09479795 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,05567311 0,09473091 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,05567311 0,09466396 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,05567311 0,09459711 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 0,05567311 0,09453035 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 0,05567311 0,09446368 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,05567311 0,09439711 ! cerebellar cortex development GO:0021695 15 10 0,000 0,05567311 0,09433064 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,05567311 0,09426425 ! activation of innate immune response GO:0002218 12 10 0,000 0,05567311 0,09419796 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,05567311 0,09413177 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,05567311 0,09406566 ! response to nicotine GO:0035094 20 10 0,000 0,05567311 0,09399965 ! establishment of cell polarity GO:0030010 16 10 0,000 0,05567311 0,09393373 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,05567311 0,09386791 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 1,000 0,05631486 0,09488344 ! hexose catabolic process GO:0019320 104 67 1,000 0,05631486 0,09481704 ! positive regulation of T cell activation GO:0050870 109 67 1,000 0,05631486 0,09475074 ! adaptive immune response GO:0002250 119 67 1,000 0,05631486 0,09468452 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! amino acid transport GO:0006865 125 68 1,000 0,05780955 0,09712973 ! viral reproduction GO:0016032 134 68 1,000 0,05780955 0,09706195 ! urogenital system development GO:0001655 137 69 1,000 0,05931796 0,09952511 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,06106801 0,10238999 ! respiratory burst GO:0045730 17 11 0,000 0,06106801 0,10231868 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,06106801 0,10224748 ! neuron fate specification GO:0048665 17 11 0,000 0,06106801 0,10217638 ! telencephalon cell migration GO:0022029 20 11 0,000 0,06106801 0,10210537 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,06106801 0,10203446 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,06106801 0,10196366 ! thyroid gland development GO:0030878 26 11 0,000 0,06106801 0,10189295 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,06106801 0,10182233 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,06106801 0,10175182 ! response to pain GO:0048265 24 11 0,000 0,06106801 0,1016814 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,06106801 0,10161109 ! T cell proliferation GO:0042098 26 11 0,000 0,06106801 0,10154086 ! bone resorption GO:0045453 16 11 0,000 0,06106801 0,10147074 ! ventral spinal cord development GO:0021517 21 11 0,000 0,06106801 0,10140071 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,06106801 0,10133078 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,06106801 0,10126094 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,06106801 0,1011912 ! melanocyte differentiation GO:0030318 21 11 0,000 0,06106801 0,10112156 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,06106801 0,10105201 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,06106801 0,10098256 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,06106801 0,10091321 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,06106801 0,10084395 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,06106801 0,10077478 ! lipid digestion GO:0044241 18 11 0,000 0,06106801 0,10070571 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,06106801 0,10063673 ! UV protection GO:0009650 19 11 0,000 0,06106801 0,10056785 ! adult heart development GO:0007512 14 11 0,000 0,06106801 0,10049906 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,06106801 0,10043037 ! temperature homeostasis GO:0001659 17 11 0,000 0,06106801 0,10036177 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,06106801 0,10029326 ! negative regulation of ossification GO:0030279 26 11 0,000 0,06106801 0,10022485 ! regulation of organ growth GO:0046620 13 11 0,000 0,06106801 0,10015653 ! pigment granule localization GO:0051875 20 11 0,000 0,06106801 0,1000883 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,06106801 0,10002017 ! vasoconstriction GO:0042310 18 11 0,000 0,06106801 0,09995213 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,06106801 0,09988418 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,06106801 0,09981632 ! snRNA metabolic process GO:0016073 24 11 0,000 0,06106801 0,09974856 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,06106801 0,09968089 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,06106801 0,09961331 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,06106801 0,09954582 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,06106801 0,09947842 ! zymogen activation GO:0031638 15 11 0,000 0,06106801 0,09941112 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,06106801 0,0993439 ! nucleosome positioning GO:0016584 15 11 0,000 0,06106801 0,09927678 ! regulation of isotype switching GO:0045191 22 11 0,000 0,06106801 0,09920974 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,06106801 0,0991428 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,06106801 0,09907595 ! acid secretion GO:0046717 18 11 0,000 0,06106801 0,09900918 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,06106801 0,09894251 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,06106801 0,09887593 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,06106801 0,09880943 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,06106801 0,09874303 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,06106801 0,09867672 ! cholesterol efflux GO:0033344 19 11 0,000 0,06106801 0,09861049 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,06106801 0,09854435 ! germ cell migration GO:0008354 25 11 0,000 0,06106801 0,0984783 ! embryonic gut development GO:0048566 15 11 0,000 0,06106801 0,09841234 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,06106801 0,09834647 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,06106801 0,09828069 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,06106801 0,09821499 ! defense response to fungus GO:0050832 13 11 0,000 0,06106801 0,09814938 ! developmental induction GO:0031128 19 11 0,000 0,06106801 0,09808386 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,06106801 0,09801843 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,06106801 0,09795309 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,06106801 0,09788783 ! lamellipodium assembly GO:0030032 20 11 0,000 0,06106801 0,09782266 ! regulation of embryonic development GO:0045995 27 11 0,000 0,06106801 0,09775757 ! humoral immune response GO:0006959 109 71 1,000 0,06237515 0,09978366 ! regulation of MAPKKK cascade GO:0043408 142 71 1,000 0,06237515 0,09971736 ! regulation of immune effector process GO:0002697 137 71 1,000 0,06237515 0,09965114 ! acute inflammatory response GO:0002526 113 72 1,000 0,06392353 0,10205708 ! regulation of caspase activity GO:0043281 122 72 1,000 0,06392353 0,1019894 ! phosphoinositide metabolic process GO:0030384 128 72 1,000 0,06392353 0,10192182 ! carbohydrate transport GO:0008643 110 72 1,000 0,06392353 0,10185432 ! learning or memory GO:0007611 147 73 1,000 0,06548484 0,10427301 ! fertilization GO:0009566 90 73 1,000 0,06548484 0,10420405 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,06643227 0,10564179 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,06643227 0,10557201 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,06643227 0,10550233 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 0,06643227 0,10543274 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,06643227 0,10536324 ! virus-host interaction GO:0019048 29 12 0,000 0,06643227 0,10529383 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,06643227 0,10522451 ! mating GO:0007618 17 12 0,000 0,06643227 0,10515528 ! protein complex disassembly GO:0043241 27 12 0,000 0,06643227 0,10508615 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,06643227 0,1050171 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 0,06643227 0,10494815 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,06643227 0,10487928 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,06643227 0,10481051 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,06643227 0,10474183 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,06643227 0,10467324 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,06643227 0,10460473 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,06643227 0,10453632 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,06643227 0,10446799 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,06643227 0,10439976 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,06643227 0,10433161 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,06643227 0,10426356 ! polyamine metabolic process GO:0006595 17 12 0,000 0,06643227 0,10419559 ! mitotic spindle organization GO:0007052 21 12 0,000 0,06643227 0,10412771 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,06643227 0,10405992 ! forebrain cell migration GO:0021885 21 12 0,000 0,06643227 0,10399221 ! asymmetric protein localization GO:0008105 20 12 0,000 0,06643227 0,1039246 ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,06643227 0,10385707 ! fear response GO:0042596 26 12 0,000 0,06643227 0,10378963 ! monoamine transport GO:0015844 18 12 0,000 0,06643227 0,10372228 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,06643227 0,10365501 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,06643227 0,10358784 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,06643227 0,10352074 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,06643227 0,10345374 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,06643227 0,10338682 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,06643227 0,10331999 ! protein homotetramerization GO:0051289 21 12 0,000 0,06643227 0,10325325 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,06643227 0,10318659 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,06643227 0,10312002 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,06643227 0,10305353 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,06643227 0,10298713 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,06643227 0,10292082 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,06643227 0,10285459 ! fucose catabolic process GO:0019317 22 12 0,000 0,06643227 0,10278844 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,06643227 0,10272238 ! histone methylation GO:0016571 26 12 0,000 0,06643227 0,10265641 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,06643227 0,10259052 ! T cell homeostasis GO:0043029 25 12 0,000 0,06643227 0,10252471 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,06643227 0,10245899 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,06643227 0,10239336 ! spleen development GO:0048536 22 12 0,000 0,06643227 0,1023278 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,06643227 0,10226234 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,06643227 0,10219695 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,06643227 0,10213165 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,06643227 0,10206643 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,06643227 0,1020013 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,06643227 0,10193624 ! response to cold GO:0009409 17 12 0,000 0,06643227 0,10187127 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,06643227 0,10180639 ! exocytosis GO:0006887 133 74 1,000 0,06705887 0,10270123 ! leukocyte mediated immunity GO:0002443 128 74 1,000 0,06705887 0,1026359 ! regulation of endopeptidase activity GO:0052548 125 74 1,000 0,06705887 0,10257065 ! defense response to bacterium GO:0042742 89 76 1,000 0,07024434 0,10737476 ! steroid biosynthetic process GO:0006694 131 76 1,000 0,07024434 0,10730659 ! monosaccharide catabolic process GO:0046365 115 76 1,000 0,07024434 0,1072385 ! regulation of catabolic process GO:0009894 161 76 1,000 0,07024434 0,1071705 ! cGMP metabolic process GO:0046068 18 13 0,000 0,07176605 0,10942276 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,07176605 0,10935346 ! peroxisomal transport GO:0043574 24 13 0,000 0,07176605 0,10928425 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,07176605 0,10921513 ! lipid localization GO:0010876 28 13 0,000 0,07176605 0,10914609 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,07176605 0,10907715 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,07176605 0,10900828 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,07176605 0,10893951 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,07176605 0,10887082 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,07176605 0,10880222 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,07176605 0,1087337 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,07176605 0,10866527 ! methionine metabolic process GO:0006555 27 13 0,000 0,07176605 0,10859693 ! plasma membrane organization GO:0007009 24 13 0,000 0,07176605 0,10852867 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,07176605 0,1084605 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,07176605 0,10839242 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,07176605 0,10832442 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,07176605 0,1082565 ! cytokine metabolic process GO:0042107 22 13 0,000 0,07176605 0,10818867 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 0,07176605 0,10812093 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,07176605 0,10805327 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,07176605 0,10798569 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,07176605 0,1079182 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,07176605 0,10785079 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,07176605 0,10778347 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,07176605 0,10771623 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,07176605 0,10764908 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,07176605 0,10758201 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,07176605 0,10751502 ! regulation of cellular pH GO:0030641 22 13 0,000 0,07176605 0,10744812 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,07176605 0,10738129 ! ribosome assembly GO:0042255 17 13 0,000 0,07176605 0,10731456 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,07176605 0,1072479 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,07176605 0,10718133 ! chromatin silencing GO:0006342 26 13 0,000 0,07176605 0,10711484 ! regulation of epidermis development GO:0045682 19 13 0,000 0,07176605 0,10704843 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,07176605 0,10698211 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,07176605 0,10691586 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,07176605 0,1068497 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,07176605 0,10678362 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,07176605 0,10671763 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,07176605 0,10665171 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,07176605 0,10658588 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,07176605 0,10652012 ! insulin secretion GO:0030073 23 13 0,000 0,07176605 0,10645445 ! actin filament polymerization GO:0030041 24 13 0,000 0,07176605 0,10638886 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,07176605 0,10632335 ! acrosome reaction GO:0007340 18 13 0,000 0,07176605 0,10625792 ! negative regulation of organelle organization GO:0010639 161 78 1,000 0,07347841 0,10872635 ! protein oligomerization GO:0051259 139 78 1,000 0,07347841 0,10865952 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 1,000 0,0751132 0,11100881 ! regulation of peptidase activity GO:0052547 134 79 1,000 0,0751132 0,11094067 ! protein import into nucleus GO:0006606 158 80 1,000 0,07675957 0,11330278 ! rRNA transcription GO:0009303 25 14 0,000 0,07706954 0,11369057 ! lactation GO:0007595 26 14 0,000 0,07706954 0,1136209 ! reproductive cellular process GO:0048610 20 14 0,000 0,07706954 0,11355133 ! tRNA modification GO:0006400 20 14 0,000 0,07706954 0,11348183 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,07706954 0,11341243 ! water transport GO:0006833 21 14 0,000 0,07706954 0,1133431 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,07706954 0,11327386 ! non-recombinational repair GO:0000726 25 14 0,000 0,07706954 0,11320471 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,07706954 0,11313564 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,07706954 0,11306666 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,07706954 0,11299776 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,07706954 0,11292894 ! RNA polyadenylation GO:0043631 30 14 0,000 0,07706954 0,1128602 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,07706954 0,11279155 ! palate development GO:0060021 31 14 0,000 0,07706954 0,11272299 ! regulated secretory pathway GO:0045055 23 14 0,000 0,07706954 0,11265451 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,07706954 0,11258611 ! arginine metabolic process GO:0006525 17 14 0,000 0,07706954 0,11251779 ! regulation of heart rate GO:0002027 24 14 0,000 0,07706954 0,11244955 ! organic alcohol transport GO:0015850 29 14 0,000 0,07706954 0,1123814 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,07706954 0,11231333 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,07706954 0,11224535 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,07706954 0,11217744 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,07706954 0,11210962 ! neutral amino acid transport GO:0015804 26 14 0,000 0,07706954 0,11204188 ! L-amino acid transport GO:0015807 30 14 0,000 0,07706954 0,11197422 ! bone mineralization GO:0030282 17 14 0,000 0,07706954 0,11190665 ! stem cell development GO:0048864 43 14 0,000 0,07706954 0,11183915 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,07706954 0,11177174 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,07706954 0,11170441 ! cerebellum development GO:0021549 21 14 0,000 0,07706954 0,11163716 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,07706954 0,11156999 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,07706954 0,1115029 ! cofactor transport GO:0051181 26 14 0,000 0,07706954 0,11143589 ! NADP metabolic process GO:0006739 24 14 0,000 0,07706954 0,11136896 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,07706954 0,11130211 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,07706954 0,11123534 ! intestinal absorption GO:0050892 25 14 0,000 0,07706954 0,11116865 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,07706954 0,11110205 ! oxygen transport GO:0015671 21 14 0,000 0,07706954 0,11103552 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,07706954 0,11096907 ! male genitalia development GO:0030539 24 14 0,000 0,07706954 0,1109027 ! regulation of axon extension GO:0030516 37 14 0,000 0,07706954 0,11083641 ! release of cytochrome c from mitochondria GO:0001836 30 14 0,000 0,07706954 0,1107702 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,07706954 0,11070407 ! nuclear import GO:0051170 161 81 1,000 0,07841736 0,11257289 ! regulation of neuron differentiation GO:0045664 167 81 1,000 0,07841736 0,11250576 ! cholesterol metabolic process GO:0008203 136 82 1,000 0,08008636 0,11483181 ! positive regulation of cell size GO:0045793 27 15 0,000 0,0823429 0,11799704 ! superoxide anion generation GO:0042554 20 15 0,000 0,0823429 0,1179268 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,0823429 0,11785665 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,0823429 0,11778658 ! copper ion transport GO:0006825 20 15 0,000 0,0823429 0,11771659 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,0823429 0,11764669 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,0823429 0,11757687 ! sulfate transport GO:0008272 23 15 0,000 0,0823429 0,11750713 ! response to cAMP GO:0051591 22 15 0,000 0,0823429 0,11743748 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,0823429 0,11736791 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,0823429 0,11729842 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,0823429 0,11722901 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,0823429 0,11715968 ! response to hexose stimulus GO:0009746 22 15 0,000 0,0823429 0,11709044 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,0823429 0,11702128 ! pituitary gland development GO:0021983 29 15 0,000 0,0823429 0,1169522 ! vesicle coating GO:0006901 33 15 0,000 0,0823429 0,1168832 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,0823429 0,11681428 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,0823429 0,11674545 ! regulation of exocytosis GO:0017157 22 15 0,000 0,0823429 0,11667669 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,0823429 0,11660802 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,0823429 0,11653943 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,0823429 0,11647092 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,0823429 0,11640248 ! regulation of vasodilation GO:0042312 26 15 0,000 0,0823429 0,11633413 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,0823429 0,11626586 ! histone deacetylation GO:0016575 20 15 0,000 0,0823429 0,11619767 ! mRNA splice site selection GO:0006376 38 15 0,000 0,0823429 0,11612956 ! tissue regeneration GO:0042246 26 15 0,000 0,0823429 0,11606153 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,0823429 0,11599358 ! water homeostasis GO:0030104 27 15 0,000 0,0823429 0,1159257 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,0823429 0,11585791 ! muscle maintenance GO:0046716 26 15 0,000 0,0823429 0,1157902 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,0823429 0,11572256 ! dopamine metabolic process GO:0042417 35 15 0,000 0,0823429 0,11565501 ! heme biosynthetic process GO:0006783 29 15 0,000 0,0823429 0,11558753 ! cell killing GO:0001906 29 15 0,000 0,0823429 0,11552013 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,0823429 0,11545281 ! detection of bacterium GO:0016045 18 15 0,000 0,0823429 0,11538557 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,0823429 0,11531841 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,0823429 0,11525132 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,0823429 0,11518432 ! peptide hormone processing GO:0016486 23 15 0,000 0,0823429 0,11511739 ! mitochondrion organization GO:0007005 148 86 1,000 0,08687101 0,12137727 ! alcohol catabolic process GO:0046164 130 86 1,000 0,08687101 0,12130683 ! amine transport GO:0015837 155 86 1,000 0,08687101 0,12123646 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,08758631 0,12216386 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,08758631 0,12209308 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,08758631 0,12202239 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,08758631 0,12195177 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,08758631 0,12188124 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,08758631 0,12181079 ! bone remodeling GO:0046849 27 16 0,000 0,08758631 0,12174042 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,08758631 0,12167013 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,08758631 0,12159992 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,08758631 0,12152979 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,08758631 0,12145975 ! startle response GO:0001964 28 16 0,000 0,08758631 0,12138978 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,08758631 0,1213199 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,08758631 0,12125009 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,08758631 0,12118037 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,08758631 0,12111073 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,08758631 0,12104116 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,08758631 0,12097168 ! protein polyubiquitination GO:0000209 34 16 0,000 0,08758631 0,12090227 ! glutamate metabolic process GO:0006536 22 16 0,000 0,08758631 0,12083295 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,08758631 0,1207637 ! response to osmotic stress GO:0006970 25 16 0,000 0,08758631 0,12069454 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,08758631 0,12062545 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,08758631 0,12055644 ! fructose metabolic process GO:0006000 25 16 0,000 0,08758631 0,12048751 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,08758631 0,12041866 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,08758631 0,12034989 ! intermediate filament-based process GO:0045103 32 16 0,000 0,08758631 0,1202812 ! negative regulation of immune response GO:0050777 35 16 0,000 0,08758631 0,12021259 ! axon cargo transport GO:0008088 43 16 0,000 0,08758631 0,12014405 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,08758631 0,12007559 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 0,08758631 0,12000721 ! DNA replication initiation GO:0006270 27 16 0,000 0,08758631 0,11993891 ! neuron recognition GO:0008038 35 16 0,000 0,08758631 0,11987068 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,08758631 0,11980254 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,08758631 0,11973447 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,08758631 0,11966648 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,08758631 0,11959856 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,08758631 0,11953072 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,08758631 0,11946296 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,08758631 0,11939528 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,08758631 0,11932767 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,08758631 0,11926014 ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,08758631 0,11919268 ! protein localization in nucleus GO:0034504 176 87 1,000 0,08859346 0,12049511 ! cellular respiration GO:0045333 135 88 1,000 0,09032606 0,1227822 ! regulation of cell morphogenesis GO:0022604 215 89 1,000 0,09206866 0,12508029 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,09279993 0,12600261 ! metencephalon development GO:0022037 30 17 0,000 0,09279993 0,12593155 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,09279993 0,12586056 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,09279993 0,12578965 ! signal complex assembly GO:0007172 41 17 0,000 0,09279993 0,12571882 ! endothelial cell migration GO:0043542 28 17 0,000 0,09279993 0,12564808 ! inositol metabolic process GO:0006020 28 17 0,000 0,09279993 0,12557741 ! gene silencing by RNA GO:0031047 36 17 0,000 0,09279993 0,12550682 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,09279993 0,12543631 ! glial cell development GO:0021782 27 17 0,000 0,09279993 0,12536588 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,09279993 0,12529553 ! adult walking behavior GO:0007628 33 17 0,000 0,09279993 0,12522526 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,09279993 0,12515506 ! heart looping GO:0001947 30 17 0,000 0,09279993 0,12508495 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,09279993 0,12501491 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,09279993 0,12494495 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,09279993 0,12487507 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,09279993 0,12480527 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,09279993 0,12473555 ! glycine metabolic process GO:0006544 28 17 0,000 0,09279993 0,1246659 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,09279993 0,12459633 ! NAD metabolic process GO:0019674 29 17 0,000 0,09279993 0,12452684 ! membrane budding GO:0006900 37 17 0,000 0,09279993 0,12445743 ! DNA integration GO:0015074 29 17 0,000 0,09279993 0,1243881 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,09279993 0,12431884 ! regulation of protein binding GO:0043393 33 17 0,000 0,09279993 0,12424966 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,09279993 0,12418055 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,09279993 0,12411152 ! genitalia development GO:0048806 30 17 0,000 0,09279993 0,12404257 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,09279993 0,1239737 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,09279993 0,1239049 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,09279993 0,12383618 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,09279993 0,12376753 ! steroid catabolic process GO:0006706 31 17 0,000 0,09279993 0,12369896 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,09279993 0,12363047 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,09279993 0,12356205 ! gas transport GO:0015669 25 17 0,000 0,09279993 0,12349371 ! organic cation transport GO:0015695 31 17 0,000 0,09279993 0,12342545 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,09279993 0,12335725 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,09279993 0,12328914 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,09279993 0,1232211 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,09279993 0,12315313 ! sterol metabolic process GO:0016125 152 91 1,000 0,09558316 0,12677679 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,09798393 0,12988944 ! neuron maturation GO:0042551 42 18 0,000 0,09798393 0,12981792 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,09798393 0,12974647 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,09798393 0,1296751 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,09798393 0,12960381 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,09798393 0,1295326 ! memory GO:0007613 31 18 0,000 0,09798393 0,12946147 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,09798393 0,12939041 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,09798393 0,12931944 ! patterning of blood vessels GO:0001569 39 18 0,000 0,09798393 0,12924854 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,09798393 0,12917772 GO:0042744|hydrogen peroxide catabolic process, ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,09798393 0,12910697 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,09798393 0,12903631 ! glutamine metabolic process GO:0006541 29 18 0,000 0,09798393 0,12896572 ! response to fungus GO:0009620 21 18 0,000 0,09798393 0,12889521 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,09798393 0,12882477 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,09798393 0,12875442 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,09798393 0,12868414 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,09798393 0,12861393 ! vitamin transport GO:0051180 27 18 0,000 0,09798393 0,1285438 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,09798393 0,12847375 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,09798393 0,12840378 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,09798393 0,12833388 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,09798393 0,12826406 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,09798393 0,12819431 ! female pregnancy GO:0007565 164 94 1,000 0,1009257 0,13197132 ! forebrain development GO:0030900 188 95 1,000 0,10272477 0,13425084 ! protein secretion GO:0009306 39 19 0,000 0,10313848 0,13471834 ! negative regulation of defense response GO:0031348 25 19 0,000 0,10313848 0,13464524 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,10313848 0,13457222 ! skin development GO:0043588 36 19 0,000 0,10313848 0,13449928 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,10313848 0,13442642 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,10313848 0,13435364 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,10313848 0,13428094 ! bile acid metabolic process GO:0008206 29 19 0,000 0,10313848 0,13420832 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,10313848 0,13413577 ! cerebral cortex development GO:0021987 36 19 0,000 0,10313848 0,13406331 ! pigmentation during development GO:0048066 41 19 0,000 0,10313848 0,13399092 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,10313848 0,13391861 GO:0030968|endoplasmic reticulum unfolded protein response, ! heme metabolic process GO:0042168 36 19 0,000 0,10313848 0,13384638 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,10313848 0,13377422 ! peptide cross-linking GO:0018149 37 19 0,000 0,10313848 0,13370214 ! protein export from nucleus GO:0006611 36 19 0,000 0,10313848 0,13363015 ! heart process GO:0003015 30 19 0,000 0,10313848 0,13355822 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,10313848 0,13348638 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,10313848 0,13341461 ! visual learning GO:0008542 36 19 0,000 0,10313848 0,13334292 ! cellular pigmentation GO:0033059 36 19 0,000 0,10313848 0,13327131 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,10313848 0,13319977 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,10313848 0,13312832 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,10313848 0,13305693 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,10313848 0,13298563 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,10313848 0,1329144 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,10313848 0,13284324 ! cilium assembly GO:0042384 37 19 0,000 0,10313848 0,13277217 ! response to virus GO:0009615 160 98 1,000 0,1081744 0,13918053 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,10826374 0,13922104 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,10826374 0,13914667 ! positive regulation of ossification GO:0045778 47 20 0,000 0,10826374 0,13907238 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,10826374 0,13899817 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,10826374 0,13892403 ! cAMP metabolic process GO:0046058 36 20 0,000 0,10826374 0,13884998 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,10826374 0,13877601 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 0,10826374 0,13870211 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,10826374 0,13862829 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,10826374 0,13855456 ! response to alkaloid GO:0043279 38 20 0,000 0,10826374 0,1384809 ! retinoid metabolic process GO:0001523 32 20 0,000 0,10826374 0,13840731 GO:0016101|diterpenoid metabolic process, ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,10826374 0,13833381 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,10826374 0,13826038 ! cellular response to starvation GO:0009267 33 20 0,000 0,10826374 0,13818704 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,10826374 0,13811377 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,10826374 0,13804057 ! body fluid secretion GO:0007589 31 20 0,000 0,10826374 0,13796746 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,10826374 0,13789442 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,10826374 0,13782146 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,10826374 0,13774858 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,10826374 0,13767577 ! sensory perception of pain GO:0019233 30 20 0,000 0,10826374 0,13760304 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,10826374 0,13753039 ! diencephalon development GO:0021536 34 20 0,000 0,10826374 0,13745782 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,10826374 0,13738532 GO:0006626|protein targeting to mitochondrion, ! detection of chemical stimulus GO:0009593 37 20 0,000 0,10826374 0,1373129 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,10826374 0,13724055 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,10826374 0,13716828 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,10826374 0,13709609 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,10826374 0,13702397 ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,10826374 0,13695193 ! actin filament-based movement GO:0030048 43 20 0,000 0,10826374 0,13687996 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,10826374 0,13680807 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,10826374 0,13673625 ! negative regulation of translation GO:0017148 29 20 0,000 0,10826374 0,13666451 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,10826374 0,13659285 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,10826374 0,13652126 ! regulation of cell killing GO:0031341 42 21 0,000 0,11335989 0,14287265 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,11335989 0,14279785 ! glycerol metabolic process GO:0006071 34 21 0,000 0,11335989 0,14272312 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,11335989 0,14264848 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,11335989 0,14257391 ! ovarian follicle development GO:0001541 35 21 0,000 0,11335989 0,14249942 ! smooth muscle contraction GO:0006939 46 21 0,000 0,11335989 0,14242501 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,11335989 0,14235067 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,11335989 0,14227641 ! cytolysis GO:0019835 24 21 0,000 0,11335989 0,14220223 ! vasodilation GO:0042311 39 21 0,000 0,11335989 0,14212813 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,11335989 0,14205411 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,11335989 0,14198016 ! DNA modification GO:0006304 34 21 0,000 0,11335989 0,14190629 ! collagen fibril organization GO:0030199 59 21 0,000 0,11335989 0,14183249 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,11335989 0,14175878 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,11335989 0,14168514 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,11335989 0,14161157 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,11335989 0,14153808 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,11335989 0,14146467 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,11335989 0,14139134 ! collagen catabolic process GO:0030574 28 21 0,000 0,11335989 0,14131808 ! sperm-egg recognition GO:0035036 21 21 0,000 0,11335989 0,14124489 ! gut development GO:0048565 39 21 0,000 0,11335989 0,14117178 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,11842707 0,14740587 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,11842707 0,14732965 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,11842707 0,14725351 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,11842707 0,14717745 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,11842707 0,14710147 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,11842707 0,14702556 ! regeneration GO:0031099 41 22 0,000 0,11842707 0,14694974 ! keratinization GO:0031424 28 22 0,000 0,11842707 0,14687399 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,11842707 0,14679832 ! sensory perception of taste GO:0050909 28 22 0,000 0,11842707 0,14672273 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,11842707 0,14664722 ! vacuolar transport GO:0007034 36 22 0,000 0,11842707 0,14657178 ! lysosome organization GO:0007040 41 22 0,000 0,11842707 0,14649642 ! central nervous system neuron development GO:0021954 46 22 0,000 0,11842707 0,14642114 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,11842707 0,14634594 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,11842707 0,14627081 ! fucose metabolic process GO:0006004 39 22 0,000 0,11842707 0,14619576 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,11842707 0,14612079 ! ureteric bud development GO:0001657 43 22 0,000 0,11842707 0,14604589 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,11842707 0,14597108 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,11842707 0,14589633 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,11842707 0,14582167 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,11842707 0,14574708 ! sarcomere organization GO:0045214 30 22 0,000 0,11842707 0,14567257 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,11842707 0,14559813 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,11842707 0,14552377 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,11842707 0,14544948 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,11842707 0,14537528 ! protein stabilization GO:0050821 39 22 0,000 0,11842707 0,14530114 ! positive regulation of DNA replication GO:0045740 43 23 0,000 0,12346547 0,15140567 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,12346547 0,15132854 ! gluconeogenesis GO:0006094 33 23 0,000 0,12346547 0,15125149 ! viral genome replication GO:0019079 41 23 0,000 0,12346547 0,15117452 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,12346547 0,15109762 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,12346547 0,1510208 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,12346547 0,15094407 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,12346547 0,15086741 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,12346547 0,15079082 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,12346547 0,15071432 ! visual behavior GO:0007632 42 23 0,000 0,12346547 0,15063789 ! response to ethanol GO:0045471 46 23 0,000 0,12346547 0,15056154 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,12346547 0,15048527 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,12346547 0,15040907 ! peroxisome organization GO:0007031 37 23 0,000 0,12346547 0,15033296 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,12346547 0,15025692 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,12346547 0,15018095 GO:0042278|purine nucleoside metabolic process, ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,12346547 0,15010506 GO:0051693|actin filament capping, ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,12346547 0,15002925 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,12346547 0,14995352 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,12346547 0,14987786 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,12346547 0,14980228 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,12346547 0,14972678 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,12346547 0,14965135 ! fatty acid transport GO:0015908 44 23 0,000 0,12346547 0,14957599 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,12346547 0,14950072 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,12346547 0,14942551 ! cell-cell recognition GO:0009988 25 23 0,000 0,12346547 0,14935039 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,12346547 0,14927534 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,12346547 0,14920036 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,12346547 0,14912546 ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,12847524 0,15509856 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,12847524 0,15502077 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,12847524 0,15494307 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,12847524 0,15486544 ! vesicle docking GO:0048278 47 24 0,000 0,12847524 0,15478789 ! spinal cord development GO:0021510 47 24 0,000 0,12847524 0,15471042 ! vacuole organization GO:0007033 43 24 0,000 0,12847524 0,15463303 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,12847524 0,15455571 ! digestive system process GO:0022600 39 24 0,000 0,12847524 0,15447847 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,12847524 0,15440131 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,12847524 0,15432423 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,12847524 0,15424722 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,12847524 0,15417029 ! membrane depolarization GO:0051899 39 24 0,000 0,12847524 0,15409343 ! pentose metabolic process GO:0019321 35 24 0,000 0,12847524 0,15401665 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,12847524 0,15393995 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,12847524 0,15386333 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,12847524 0,15378678 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,12847524 0,1537103 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,12847524 0,15363391 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,12847524 0,15355759 ! regulation of amine transport GO:0051952 40 24 0,000 0,12847524 0,15348134 ! protein tetramerization GO:0051262 52 24 0,000 0,12847524 0,15340517 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,13345654 0,15927402 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,13345654 0,15919506 ! phototransduction GO:0007602 33 25 0,000 0,13345654 0,15911617 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,13345654 0,15903736 GO:0006479|protein amino acid methylation, ! sperm motility GO:0030317 31 25 0,000 0,13345654 0,15895863 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,13345654 0,15887998 ! receptor metabolic process GO:0043112 46 25 0,000 0,13345654 0,1588014 ! chromosome condensation GO:0030261 45 25 0,000 0,13345654 0,1587229 ! response to starvation GO:0042594 42 25 0,000 0,13345654 0,15864448 ! neural crest cell development GO:0014032 54 25 0,000 0,13345654 0,15856614 GO:0014033|neural crest cell differentiation, ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,13345654 0,15848787 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,13345654 0,15840968 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,13345654 0,15833157 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! immunoglobulin production GO:0002377 55 25 0,000 0,13345654 0,15825354 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,13345654 0,15817558 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,13345654 0,1580977 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,13345654 0,1580199 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,13345654 0,15794217 ! telomere organization GO:0032200 43 25 0,000 0,13345654 0,15786452 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,13345654 0,15778694 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,13345654 0,15770945 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,13840953 0,16348224 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,13840953 0,16340203 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,13840953 0,16332189 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,13840953 0,16324183 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,13840953 0,16316185 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,13840953 0,16308195 ! molting cycle process GO:0022404 50 26 0,000 0,13840953 0,16300212 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,13840953 0,16292237 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,13840953 0,16284271 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,13840953 0,16276311 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,13840953 0,1626836 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 0,000 0,13840953 0,16260417 ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,13840953 0,16252481 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,13840953 0,16244553 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,13840953 0,16236633 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,13840953 0,1622872 ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,13840953 0,16220815 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,13840953 0,16212918 ! leukocyte proliferation GO:0070661 52 26 0,000 0,13840953 0,16205028 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,13840953 0,16197147 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,13840953 0,16189272 ! neuron fate commitment GO:0048663 48 27 0,000 0,14333438 0,16757168 ! iron ion transport GO:0006826 59 27 0,000 0,14333438 0,16749029 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,14333438 0,16740899 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,14333438 0,16732776 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,14333438 0,16724661 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,14333438 0,16716554 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,14333438 0,16708455 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,14333438 0,16700364 ! autophagy GO:0006914 41 27 0,000 0,14333438 0,1669228 ! male gonad development GO:0008584 44 27 0,000 0,14333438 0,16684205 ! response to toxin GO:0009636 47 27 0,000 0,14333438 0,16676137 ! primary neural tube formation GO:0014020 51 27 0,000 0,14333438 0,16668077 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,14333438 0,16660025 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,14333438 0,1665198 ! glutathione metabolic process GO:0006749 39 27 0,000 0,14333438 0,16643944 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,14333438 0,16635915 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,14333438 0,16627894 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,14823124 0,1718768 ! circadian rhythm GO:0007623 50 28 0,000 0,14823124 0,17179401 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,14823124 0,17171129 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,14823124 0,17162866 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,14823124 0,17154611 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,14823124 0,17146363 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,14823124 0,17138124 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,14823124 0,17129892 ! synaptogenesis GO:0007416 42 28 0,000 0,14823124 0,17121669 ! peptidyl-tyrosine modification GO:0018212 50 28 0,000 0,14823124 0,17113453 ! lipid oxidation GO:0034440 43 28 0,000 0,14823124 0,17105245 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,14823124 0,17097045 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,14823124 0,17088853 ! translational initiation GO:0006413 65 29 0,000 0,15310027 0,17641726 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,15310027 0,17633281 ! regulation of pH GO:0006885 43 29 0,000 0,15310027 0,17624844 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,15310027 0,17616415 ! catechol metabolic process GO:0009712 54 29 0,000 0,15310027 0,17607994 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,15310027 0,17599582 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,15310027 0,17591177 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,15310027 0,1758278 GO:0002764|immune response-regulating signal transduction, ! cell fate determination GO:0001709 60 29 0,000 0,15310027 0,17574391 ! detection of light stimulus GO:0009583 38 29 0,000 0,15310027 0,17566011 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,15310027 0,17557638 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,15310027 0,17549273 ! regulation of coagulation GO:0050818 46 29 0,000 0,15310027 0,17540916 ! phenol metabolic process GO:0018958 55 30 0,000 0,15794162 0,18086985 ! zinc ion transport GO:0006829 45 30 0,000 0,15794162 0,1807838 ! membrane docking GO:0022406 61 30 0,000 0,15794162 0,18069783 ! regulation of innate immune response GO:0045088 51 30 0,000 0,15794162 0,18061195 ! myofibril assembly GO:0030239 47 30 0,000 0,15794162 0,18052615 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,15794162 0,18044043 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,15794162 0,18035479 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,15794162 0,18026923 ! phospholipid transport GO:0015914 51 30 0,000 0,15794162 0,18018376 ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,15794162 0,18009836 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 48 30 0,000 0,15794162 0,18001305 ! eye morphogenesis GO:0048592 60 30 0,000 0,15794162 0,17992782 ! response to heat GO:0009408 50 30 0,000 0,15794162 0,17984266 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,16275546 0,18523635 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,16275546 0,18514877 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,16275546 0,18506127 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,16275546 0,18497385 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,16275546 0,18488652 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,16275546 0,18479927 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,16275546 0,1847121 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,16275546 0,18462501 ! ovulation cycle process GO:0022602 49 31 0,000 0,16275546 0,18453801 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,16275546 0,18445108 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,16275546 0,18436424 ! mesoderm formation GO:0001707 69 31 0,000 0,16275546 0,18427748 ! natural killer cell activation GO:0030101 45 31 0,000 0,16275546 0,1841908 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,16275546 0,18410421 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,16275546 0,18401769 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,16275546 0,18393126 ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,16275546 0,18384491 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,16754195 0,1891628 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,16754195 0,18907407 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,16754195 0,18898543 ! cholesterol transport GO:0030301 56 32 0,000 0,16754195 0,18889687 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,16754195 0,18880839 ! spliceosome assembly GO:0000245 67 32 0,000 0,16754195 0,18872 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,16754195 0,18863169 ! metanephros development GO:0001656 74 32 0,000 0,16754195 0,18854346 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,16754195 0,18845532 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,16754195 0,18836725 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,16754195 0,18827927 ! regulation of protein import into nucleus GO:0042306 63 32 0,000 0,16754195 0,18819137 ! muscle cell development GO:0055001 49 32 0,000 0,16754195 0,18810356 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,16754195 0,18801582 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,16754195 0,18792817 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,16754195 0,1878406 ! ovulation cycle GO:0042698 51 32 0,000 0,16754195 0,18775311 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,16754195 0,1876657 ! gene silencing GO:0016458 65 32 0,000 0,16754195 0,18757837 ! post-embryonic development GO:0009791 69 33 0,000 0,17230122 0,19281709 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,17230122 0,19272745 ! protein targeting to membrane GO:0006612 68 33 0,000 0,17230122 0,19263789 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,17230122 0,19254841 ! ceramide metabolic process GO:0006672 64 33 0,000 0,17230122 0,19245902 ! formation of primary germ layer GO:0001704 72 33 0,000 0,17230122 0,19236972 ! cell fate specification GO:0001708 52 33 0,000 0,17230122 0,19228049 ! sterol transport GO:0015918 57 33 0,000 0,17230122 0,19219135 ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,17230122 0,19210229 ! adult locomotory behavior GO:0008344 59 33 0,000 0,17230122 0,19201331 ! glial cell differentiation GO:0010001 63 34 0,000 0,17703344 0,19719559 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,17703344 0,19710433 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,17703344 0,19701317 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,17703344 0,19692208 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,17703344 0,19683108 ! mismatch repair GO:0006298 46 34 0,000 0,17703344 0,19674017 ! spermatid development GO:0007286 63 34 0,000 0,17703344 0,19664934 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,17703344 0,19655859 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,17703344 0,19646793 ! odontogenesis GO:0042476 66 35 0,000 0,18173877 0,20159681 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,18173877 0,2015039 GO:0006639|acylglycerol metabolic process, ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 0,18173877 0,20141109 ! cytokine production GO:0001816 59 35 0,000 0,18173877 0,20131836 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,18173877 0,20122571 ! neural tube formation GO:0001841 67 35 0,000 0,18173877 0,20113315 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,18641734 0,20621615 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,18641734 0,20612138 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,18641734 0,2060267 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,18641734 0,20593211 ! positive regulation of cell development GO:0010720 80 36 0,000 0,18641734 0,2058376 ! regulation of proteolysis GO:0030162 72 36 0,000 0,18641734 0,20574318 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,18641734 0,20564884 ! embryonic organ development GO:0048568 57 36 0,000 0,18641734 0,2055546 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,18641734 0,20546043 ! RNA export from nucleus GO:0006405 56 37 0,000 0,19106932 0,21049121 ! actomyosin structure organization GO:0031032 62 37 0,000 0,19106932 0,21039487 ! organic anion transport GO:0015711 68 37 0,000 0,19106932 0,21029862 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,19106932 0,21020247 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,19106932 0,21010639 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,19106932 0,21001041 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,19106932 0,20991452 GO:0015986|ATP synthesis coupled proton transport, ! pigment metabolic process GO:0042440 80 37 0,000 0,19106932 0,20981871 ! spermatid differentiation GO:0048515 66 37 0,000 0,19106932 0,20972299 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,19569486 0,21470216 GO:0006956|complement activation, ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,19569486 0,2146043 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,19569486 0,21450653 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,19569486 0,21440885 ! lipid homeostasis GO:0055088 67 38 0,000 0,19569486 0,21431126 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,19569486 0,21421375 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,19569486 0,21411634 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,19569486 0,21401901 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,19569486 0,21392178 ! mRNA catabolic process GO:0006402 71 39 0,000 0,2002941 0,21884995 ! ear morphogenesis GO:0042471 60 39 0,000 0,2002941 0,21875061 ! organic ether metabolic process GO:0018904 55 39 0,000 0,2002941 0,21865136 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,2002941 0,2185522 ! ion transmembrane transport GO:0034220 66 39 0,000 0,2002941 0,21845313 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,2002941 0,21835414 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,2002941 0,21825525 ! RNA modification GO:0009451 57 39 0,000 0,2002941 0,21815645 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,2002941 0,21805774 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,20486719 0,22293553 ! feeding behavior GO:0007631 59 40 0,000 0,20486719 0,22283474 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,20486719 0,22273405 ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,20486719 0,22263345 ! maintenance of protein location GO:0045185 91 40 0,000 0,20486719 0,22253293 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,20941428 0,22736947 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,20941428 0,22726692 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,20941428 0,22716445 ! gliogenesis GO:0042063 88 41 0,000 0,20941428 0,22706208 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,20941428 0,2269598 ! T cell differentiation GO:0030217 81 41 0,000 0,20941428 0,22685761 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,20941428 0,22675551 ! polyol metabolic process GO:0019751 66 41 0,000 0,20941428 0,22665351 ! response to reactive oxygen species GO:0000302 67 42 0,000 0,21393551 0,23144283 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,21393551 0,23133881 ! regulation of tube size GO:0035150 71 42 0,000 0,21393551 0,23123488 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,21393551 0,23113105 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,21393551 0,23102731 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,21393551 0,23092366 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,21393551 0,23082011 ! neuron migration GO:0001764 79 42 0,000 0,21393551 0,23071665 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,21843105 0,23545927 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,21843105 0,23535383 ! neural tube development GO:0021915 77 43 0,000 0,21843105 0,23524848 ! striated muscle contraction GO:0006941 77 43 0,000 0,21843105 0,23514322 ! phagocytosis GO:0006909 90 43 0,000 0,21843105 0,23503806 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,21843105 0,23493299 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,22290102 0,23963353 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,22290102 0,2395265 ! biopolymer methylation GO:0043414 84 44 0,000 0,22290102 0,23941957 ! B cell differentiation GO:0030183 107 44 0,000 0,22290102 0,23931274 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,22290102 0,239206 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,22734557 0,24386689 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,22734557 0,24375822 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,22734557 0,24364964 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,22734557 0,24354116 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,22734557 0,24343277 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,22734557 0,24332448 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,22734557 0,24321629 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,22734557 0,24310819 ! cell growth GO:0016049 84 45 0,000 0,22734557 0,24300019 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,23176485 0,24761377 ! regulation of gene-specific transcription GO:0032583 96 46 0,000 0,23176485 0,24750387 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,23176485 0,24739406 ! pigmentation GO:0043473 100 46 0,000 0,23176485 0,24728436 ! response to calcium ion GO:0051592 81 47 0,000 0,236159 0,25186106 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,236159 0,25174947 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,236159 0,25163797 ! methylation GO:0032259 90 47 0,000 0,236159 0,25152658 ! mitochondrial transport GO:0006839 82 48 0,000 0,24052816 0,2560667 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,24052816 0,25595345 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,24052816 0,25584029 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,24052816 0,25572724 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,24052816 0,25561429 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,24487247 0,26011619 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,24487247 0,26000139 ! regulation of ion transport GO:0043269 77 49 0,000 0,24487247 0,25988671 ! peptide metabolic process GO:0006518 76 49 0,000 0,24487247 0,25977212 ! response to temperature stimulus GO:0009266 76 49 0,000 0,24487247 0,25965763 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,24487247 0,25954324 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,24487247 0,25942896 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,24487247 0,25931477 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,24487247 0,25920069 ! neuromuscular process GO:0050905 99 50 0,000 0,24919208 0,26365705 ! inner ear development GO:0048839 79 50 0,000 0,24919208 0,26354116 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,24919208 0,26342537 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,25348712 0,26784805 ! excretion GO:0007588 83 51 0,000 0,25348712 0,26773047 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,25348712 0,26761299 ! chromatin remodeling GO:0006338 109 51 0,000 0,25348712 0,26749561 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,25348712 0,26737834 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,25348712 0,26726117 ! positive regulation of growth GO:0045927 90 52 0,000 0,25775773 0,27164481 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,25775773 0,27152587 ! amino acid activation GO:0043038 92 52 0,000 0,25775773 0,27140704 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 76 53 0,000 0,26200405 0,27575754 ! RNA catabolic process GO:0006401 93 53 0,000 0,26200405 0,27563697 ! regulation of translational initiation GO:0006446 82 53 0,000 0,26200405 0,2755165 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,26200405 0,27539613 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,26200405 0,27527587 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,26200405 0,27515572 ! regulation of neuron apoptosis GO:0043523 100 53 0,000 0,26200405 0,27503566 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,26200405 0,27491572 ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,26622622 0,27922419 ! cell recognition GO:0008037 85 54 0,000 0,26622622 0,27910252 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,26622622 0,27898096 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,26622622 0,27885951 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,26622622 0,27873816 ! chloride transport GO:0006821 90 55 0,000 0,27042437 0,28301046 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,27042437 0,28288741 ! gastrulation GO:0007369 112 55 0,000 0,27042437 0,28276447 ! heart morphogenesis GO:0003007 97 55 0,000 0,27042437 0,28264163 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,27042437 0,28251891 ! RNA elongation GO:0006354 79 55 0,000 0,27042437 0,28239628 ! nuclear export GO:0051168 97 55 0,000 0,27042437 0,28227377 ! regulation of actin filament length GO:0030832 105 56 0,000 0,27459865 0,28650665 ! sensory perception of smell GO:0007608 80 56 0,000 0,27459865 0,28638246 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,27459865 0,28625838 ! proton transport GO:0015992 94 56 0,000 0,27459865 0,28613441 ! hydrogen transport GO:0006818 97 58 0,000 0,28287609 0,29463198 ! regulation of endocytosis GO:0030100 91 58 0,000 0,28287609 0,29450449 ! adult behavior GO:0030534 99 58 0,000 0,28287609 0,29437711 ! regulation of cellular component size GO:0032535 109 59 0,000 0,28697953 0,29851827 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,28697953 0,29838926 GO:0032313|regulation of Rab GTPase activity, ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,29105963 0,30250085 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,29105963 0,30237024 ! camera-type eye development GO:0043010 116 60 0,000 0,29105963 0,30223973 ! kidney development GO:0001822 122 60 0,000 0,29105963 0,30210935 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,29511651 0,30618815 ! tRNA processing GO:0008033 89 61 0,000 0,29511651 0,30605618 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,29511651 0,30592431 ! ear development GO:0043583 103 62 0,000 0,29915031 0,30997229 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,29915031 0,30983885 ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,30316117 0,3138579 ! detection of external stimulus GO:0009581 91 63 0,000 0,30316117 0,31372291 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,30316117 0,31358803 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,3071492 0,31757669 ! cell redox homeostasis GO:0045454 102 64 0,000 0,3071492 0,31744028 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,3071492 0,31730398 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,31111454 0,32126248 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,31111454 0,32112466 GO:0035113|embryonic appendage morphogenesis, ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,31505731 0,32505484 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,31505731 0,32491551 ! extracellular matrix organization GO:0030198 133 66 0,000 0,31505731 0,3247763 ! secondary metabolic process GO:0019748 116 66 0,000 0,31505731 0,32463721 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,31897765 0,32853606 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,31897765 0,32839548 ! activation of MAPK activity GO:0000187 115 67 0,000 0,31897765 0,32825502 ! activation of immune response GO:0002253 105 67 0,000 0,31897765 0,32811468 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,32287568 0,33198243 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,32675153 0,33582409 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,32675153 0,33568069 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,32675153 0,33553742 ! antigen processing and presentation GO:0019882 104 69 0,000 0,32675153 0,33539428 ! appendage morphogenesis GO:0035107 135 70 0,000 0,33060532 0,33920529 GO:0035108|limb morphogenesis, ! amine catabolic process GO:0009310 117 71 0,000 0,33443718 0,34299056 ! appendage development GO:0048736 136 71 0,000 0,33443718 0,34284442 GO:0060173|limb development, ! B cell activation GO:0042113 160 71 0,000 0,33443718 0,34269841 ! regulation of blood pressure GO:0008217 125 73 0,000 0,3420356 0,35033532 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,3420356 0,35018624 ! transition metal ion transport GO:0000041 126 74 0,000 0,34580241 0,35389221 ! neurotransmitter transport GO:0006836 123 74 0,000 0,34580241 0,35374175 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,34580241 0,35359141 ! eye development GO:0001654 143 74 0,000 0,34580241 0,3534412 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,34954777 0,35711759 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,34954777 0,35696602 ! rhythmic process GO:0048511 128 75 0,000 0,34954777 0,35681457 ! lymphocyte differentiation GO:0030098 167 75 0,000 0,34954777 0,35666325 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,35327182 0,3603103 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,35697466 0,36393264 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,35697466 0,3637785 ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,36065643 0,36737484 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,36431724 0,3709468 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,36795721 0,37449453 ! response to metal ion GO:0010038 140 80 0,000 0,36795721 0,37433618 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,36795721 0,37417796 ! inorganic anion transport GO:0015698 138 80 0,000 0,36795721 0,37401988 ! T cell activation GO:0042110 168 81 0,000 0,37157646 0,37753926 ! digestion GO:0007586 112 81 0,000 0,37157646 0,37737989 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,37157646 0,37722066 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,37517511 0,38071333 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,37517511 0,38055283 ! regulation of lyase activity GO:0051339 160 83 0,000 0,37875326 0,38402037 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,38231104 0,38746435 ! response to unfolded protein GO:0006986 131 85 0,000 0,38584857 0,39088491 ! nucleosome assembly GO:0006334 122 85 0,000 0,38584857 0,39072039 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,38584857 0,39055602 ! amine biosynthetic process GO:0009309 138 86 0,000 0,38936595 0,39395058 ! response to inorganic substance GO:0010035 153 86 0,000 0,38936595 0,39378499 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,38936595 0,39361953 ! chromatin assembly GO:0031497 124 86 0,000 0,38936595 0,39345421 ! tube morphogenesis GO:0035239 176 86 0,000 0,38936595 0,39328903 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,39286331 0,3966551 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,39286331 0,39648872 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,39634075 0,39983054 ! cellular defense response GO:0006968 114 89 0,000 0,39979838 0,40314959 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,40323633 0,406446 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,40323633 0,4062758 ! response to protein stimulus GO:0051789 149 91 0,000 0,4066547 0,40954843 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,4066547 0,40937707 ! nucleosome organization GO:0034728 138 92 0,000 0,4100536 0,41262608 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,4100536 0,41245358 ! vitamin metabolic process GO:0006766 139 92 0,000 0,4100536 0,41228122 ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,41343314 0,41550549 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,41343314 0,415332 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,41679344 0,41853298 ! transcription initiation GO:0006352 153 94 0,000 0,41679344 0,41835837 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,42345672 0,42486942 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,42345672 0,42469232 ! positive regulation of immune response GO:0050778 156 96 0,000 0,42345672 0,42451536 ! detection of stimulus GO:0051606 151 96 0,000 0,42345672 0,42433855 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,42675992 0,4274706 ! hormone metabolic process GO:0042445 157 97 0,000 0,42675992 0,42729271 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,43004431 0,43040208 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,43004431 0,43022312 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,43330999 0,43330999