pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6821-VanDeVijver-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/vantveer-oligo_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of cell migration GO:0030334 71 71 5,000 2,837E-06 5,228E-03 ! protein sumoylation GO:0016925 6 6 2,000 3,598E-06 3,316E-03 ! regulation of locomotion GO:0040012 79 79 5,000 5,321E-06 3,269E-03 ! regulation of cell motion GO:0051270 79 79 5,000 5,321E-06 2,452E-03 ! regulation of anatomical structure morphogenesis GO:0022603 90 86 5,000 8,736E-06 3,22E-03 ! regulation of intracellular protein transport GO:0033157 25 25 3,000 1,135E-05 3,486E-03 ! regulation of nucleocytoplasmic transport GO:0046822 27 27 3,000 1,561E-05 4,111E-03 ! regulation of intracellular transport GO:0032386 31 31 3,000 2,753E-05 6,342E-03 ! positive regulation of nucleocytoplasmic transport GO:0046824 11 11 2,000 2,909E-05 5,957E-03 GO:0032388|positive regulation of intracellular transport, ! regulation of angiogenesis GO:0045765 35 34 3,000 4,007E-05 7,384E-03 ! lung development GO:0030324 38 37 3,000 5,635E-05 9,441E-03 ! positive regulation of epithelial cell proliferation GO:0050679 14 14 2,000 6,341E-05 9,738E-03 ! response to retinoic acid GO:0032526 14 14 2,000 6,341E-05 8,989E-03 GO:0033189|response to vitamin A, ! respiratory tube development GO:0030323 40 39 3,000 6,959E-05 9,161E-03 ! respiratory system development GO:0060541 40 39 3,000 6,959E-05 8,55E-03 ! response to vitamin GO:0033273 15 15 2,000 7,894E-05 9,093E-03 ! tube development GO:0035295 83 81 4,000 9,515E-05 0,01031489 ! cellular response to reactive oxygen species GO:0034614 16 16 2,000 9,676E-05 9,908E-03 ! cellular response to oxidative stress GO:0034599 19 19 2,000 1,654E-04 0,01604592 ! protein modification by small protein conjugation GO:0032446 52 51 3,000 2,011E-04 0,01852834 ! regulation of protein transport GO:0051223 53 53 3,000 2,336E-04 0,02050472 GO:0070201|regulation of establishment of protein localization, ! protein modification by small protein conjugation or removal GO:0070647 56 55 3,000 2,699E-04 0,02260642 ! regulation of protein localization GO:0032880 58 57 3,000 3,099E-04 0,02483567 ! negative regulation of blood pressure GO:0045776 6 5 1,000 3,26E-04 0,02503335 ! mRNA stabilization GO:0048255 5 5 1,000 3,26E-04 0,02403201 GO:0043489|RNA stabilization, ! glucocorticoid metabolic process GO:0008211 5 5 1,000 3,26E-04 0,02310771 ! endocrine pancreas development GO:0031018 5 5 1,000 3,26E-04 0,02225187 ! regulation of phospholipase A2 activity GO:0032429 5 5 1,000 3,26E-04 0,02145716 ! corticosteroid receptor signaling pathway GO:0031958 5 5 1,000 3,26E-04 0,02071725 GO:0042921|glucocorticoid receptor signaling pathway, ! DNA methylation GO:0006306 5 5 1,000 3,26E-04 0,02002668 GO:0006305|DNA alkylation, ! peptidyl-lysine modification GO:0018205 5 5 1,000 3,26E-04 0,01938066 ! positive regulation of blood vessel endothelial cell migration GO:0043536 5 5 1,000 3,26E-04 0,01877501 ! N-terminal protein amino acid modification GO:0031365 6 6 1,000 4,872E-04 0,02720863 GO:0018409|peptide or protein amino-terminal blocking, ! regulation of positive chemotaxis GO:0050926 6 6 1,000 4,872E-04 0,02640837 GO:0050927|positive regulation of positive chemotaxis, ! positive regulation of transcription factor import into nucleus GO:0042993 6 6 1,000 4,872E-04 0,02565385 ! L-serine metabolic process GO:0006563 6 6 1,000 4,872E-04 0,02494124 ! ER overload response GO:0006983 6 6 1,000 4,872E-04 0,02426716 ! focal adhesion formation GO:0048041 7 6 1,000 4,872E-04 0,02362855 ! negative regulation of T cell proliferation GO:0042130 6 6 1,000 4,872E-04 0,02302269 GO:0070667|negative regulation of mast cell proliferation, ! regulation of vascular permeability GO:0043114 6 6 1,000 4,872E-04 0,02244712 ! peptidyl-serine phosphorylation GO:0018105 6 6 1,000 4,872E-04 0,02189963 ! regulation of bone resorption GO:0045124 6 6 1,000 4,872E-04 0,02137821 ! regulation of T cell differentiation in the thymus GO:0033081 6 6 1,000 4,872E-04 0,02088104 ! phosphoinositide 3-kinase cascade GO:0014065 6 6 1,000 4,872E-04 0,02040647 ! ribosomal large subunit biogenesis GO:0042273 6 6 1,000 4,872E-04 0,01995299 ! serine family amino acid biosynthetic process GO:0009070 6 6 1,000 4,872E-04 0,01951923 ! negative regulation of BMP signaling pathway GO:0030514 6 6 1,000 4,872E-04 0,01910393 ! regulation of embryonic development GO:0045995 6 6 1,000 4,872E-04 0,01870593 ! localization within membrane GO:0051668 6 6 1,000 4,872E-04 0,01832418 ! protein amino acid autophosphorylation GO:0046777 28 28 2,000 5,393E-04 0,0198799 ! regulation of epithelial cell proliferation GO:0050678 29 29 2,000 5,991E-04 0,02165158 ! positive regulation of protein transport GO:0051222 29 29 2,000 5,991E-04 0,0212352 ! regionalization GO:0003002 70 69 3,000 6,451E-04 0,02243311 ! response to reactive oxygen species GO:0000302 31 30 2,000 6,63E-04 0,02262949 ! negative regulation of cell projection organization GO:0031345 8 7 1,000 6,796E-04 0,02277119 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 7 7 1,000 6,796E-04 0,02236456 ! regulation of mRNA processing GO:0050684 7 7 1,000 6,796E-04 0,0219722 ! negative regulation of lymphocyte proliferation GO:0050672 7 7 1,000 6,796E-04 0,02159337 GO:0032945|negative regulation of mononuclear cell proliferation, GO:0070664|negative regulation of leukocyte proliferation, ! hormone catabolic process GO:0042447 7 7 1,000 6,796E-04 0,02122738 ! regulation of mRNA stability GO:0043488 7 7 1,000 6,796E-04 0,02087359 ! negative regulation of T cell activation GO:0050868 7 7 1,000 6,796E-04 0,0205314 ! negative regulation of bone remodeling GO:0046851 8 8 1,000 9,027E-04 0,02683463 ! pancreas development GO:0031016 8 8 1,000 9,027E-04 0,02640869 ! positive regulation of endothelial cell migration GO:0010595 8 8 1,000 9,027E-04 0,02599605 ! fructose metabolic process GO:0006000 8 8 1,000 9,027E-04 0,02559611 ! plasma membrane fusion GO:0045026 8 8 1,000 9,027E-04 0,02520829 ! peptidyl-serine modification GO:0018209 8 8 1,000 9,027E-04 0,02483205 ! positive regulation of leukocyte migration GO:0002687 8 8 1,000 9,027E-04 0,02446687 ! regulation of RNA stability GO:0043487 8 8 1,000 9,027E-04 0,02411228 ! regulation of bone remodeling GO:0046850 34 34 2,000 9,616E-04 0,02531884 ! mesoderm development GO:0007498 35 35 2,000 1,048E-03 0,02719282 ! regulation of cell morphogenesis GO:0022604 38 35 2,000 1,048E-03 0,02681515 ! regulation of tissue remodeling GO:0034103 35 35 2,000 1,048E-03 0,02644782 ! positive regulation of cell migration GO:0030335 36 36 2,000 1,138E-03 0,028348 ! regulation of nitric-oxide synthase activity GO:0050999 9 9 1,000 1,156E-03 0,02841655 ! viral genome replication GO:0019079 9 9 1,000 1,156E-03 0,02804265 ! positive regulation of endothelial cell proliferation GO:0001938 9 9 1,000 1,156E-03 0,02767846 ! platelet-derived growth factor receptor signaling pathway GO:0048008 9 9 1,000 1,156E-03 0,02732361 ! activation of pro-apoptotic gene products GO:0008633 9 9 1,000 1,156E-03 0,02697774 ! branching involved in ureteric bud morphogenesis GO:0001658 9 9 1,000 1,156E-03 0,02664052 GO:0060675|ureteric bud morphogenesis, ! positive regulation of protein import into nucleus GO:0042307 9 9 1,000 1,156E-03 0,02631162 ! histone acetylation GO:0016573 9 9 1,000 1,156E-03 0,02599075 ! negative regulation of tissue remodeling GO:0034104 9 9 1,000 1,156E-03 0,02567761 ! regulation of leukocyte migration GO:0002685 9 9 1,000 1,156E-03 0,02537192 ! regulation of blood vessel endothelial cell migration GO:0043535 9 9 1,000 1,156E-03 0,02507343 ! cell-matrix adhesion GO:0007160 39 38 2,000 1,334E-03 0,02858913 ! steroid hormone receptor signaling pathway GO:0030518 38 38 2,000 1,334E-03 0,02826052 ! regulation of homeostatic process GO:0032844 38 38 2,000 1,334E-03 0,02793938 ! regulation of cellular localization GO:0060341 86 85 3,000 1,413E-03 0,02926554 ! positive regulation of cell motion GO:0051272 39 39 2,000 1,439E-03 0,02947629 ! negative regulation of nucleocytoplasmic transport GO:0046823 10 10 1,000 1,44E-03 0,02916774 ! transcription from RNA polymerase III promoter GO:0006383 10 10 1,000 1,44E-03 0,0288507 ! cell-substrate junction assembly GO:0007044 11 10 1,000 1,44E-03 0,02854047 ! neuromuscular junction development GO:0007528 10 10 1,000 1,44E-03 0,02823685 ! positive regulation of biomineral formation GO:0070169 10 10 1,000 1,44E-03 0,02793962 GO:0030501|positive regulation of bone mineralization, ! regulation of erythrocyte differentiation GO:0045646 10 10 1,000 1,44E-03 0,02764858 ! regulation of BMP signaling pathway GO:0030510 10 10 1,000 1,44E-03 0,02736355 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 10 10 1,000 1,44E-03 0,02708433 ! epithelial to mesenchymal transition GO:0001837 10 10 1,000 1,44E-03 0,02681075 ! negative regulation of homeostatic process GO:0032845 10 10 1,000 1,44E-03 0,02654264 ! intracellular receptor-mediated signaling pathway GO:0030522 40 40 2,000 1,55E-03 0,02828176 ! protein amino acid acetylation GO:0006473 11 11 1,000 1,754E-03 0,03168809 ! positive regulation of nitric oxide biosynthetic process GO:0045429 11 11 1,000 1,754E-03 0,03138044 ! regulation of monooxygenase activity GO:0032768 11 11 1,000 1,754E-03 0,03107871 ! negative regulation of angiogenesis GO:0016525 11 11 1,000 1,754E-03 0,03078272 ! steroid catabolic process GO:0006706 11 11 1,000 1,754E-03 0,03049232 ! proximal/distal pattern formation GO:0009954 11 11 1,000 1,754E-03 0,03020734 ! negative regulation of lymphocyte activation GO:0051250 11 11 1,000 1,754E-03 0,02992764 ! cell-substrate adhesion GO:0031589 43 42 2,000 1,786E-03 0,03020616 ! blood vessel development GO:0001568 95 94 3,000 2,05E-03 0,03434694 ! pattern specification process GO:0007389 96 94 3,000 2,05E-03 0,03403751 ! positive regulation of protein catabolic process GO:0045732 12 12 1,000 2,097E-03 0,03450342 ! cellular response to hydrogen peroxide GO:0070301 12 12 1,000 2,097E-03 0,03419808 GO:0042744|hydrogen peroxide catabolic process, ! somitogenesis GO:0001756 13 12 1,000 2,097E-03 0,03389809 ! Wnt receptor signaling pathway GO:0016055 46 45 2,000 2,182E-03 0,03496477 ! vasculature development GO:0001944 97 96 3,000 2,215E-03 0,03518554 ! positive regulation of smooth muscle cell proliferation GO:0048661 13 13 1,000 2,469E-03 0,03889091 ! gluconeogenesis GO:0006094 13 13 1,000 2,469E-03 0,03856132 ! vasculogenesis GO:0001570 13 13 1,000 2,469E-03 0,03823728 ! regulation of nitric oxide biosynthetic process GO:0045428 13 13 1,000 2,469E-03 0,03791863 ! actin filament bundle formation GO:0051017 13 13 1,000 2,469E-03 0,03760526 ! ureteric bud development GO:0001657 13 13 1,000 2,469E-03 0,03729702 ! regulation of endothelial cell migration GO:0010594 13 13 1,000 2,469E-03 0,03699379 ! response to endoplasmic reticulum stress GO:0034976 13 13 1,000 2,469E-03 0,03669545 ! positive regulation of locomotion GO:0040017 13 13 1,000 2,469E-03 0,03640189 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, GO:0050920|regulation of chemotaxis, ! negative regulation of intracellular transport GO:0032387 13 13 1,000 2,469E-03 0,03611298 ! negative regulation of leukocyte activation GO:0002695 13 13 1,000 2,469E-03 0,03582863 ! negative regulation of myeloid cell differentiation GO:0045638 13 13 1,000 2,469E-03 0,03554872 ! tissue homeostasis GO:0001894 13 13 1,000 2,469E-03 0,03527315 GO:0048871|multicellular organismal homeostasis, ! skeletal muscle tissue development GO:0007519 50 49 2,000 2,788E-03 0,03951957 GO:0060538|skeletal muscle organ development, ! response to nutrient GO:0007584 49 49 2,000 2,788E-03 0,0392179 ! positive regulation of MAP kinase activity GO:0043406 50 49 2,000 2,788E-03 0,03892079 ! pyruvate metabolic process GO:0006090 14 14 1,000 2,87E-03 0,03976791 ! protein amino acid acylation GO:0043543 14 14 1,000 2,87E-03 0,03947114 ! regulation of neuron projection development GO:0010975 15 14 1,000 2,87E-03 0,03917876 ! regulation of behavior GO:0050795 14 14 1,000 2,87E-03 0,03889068 ! regulation of vasoconstriction GO:0019229 14 14 1,000 2,87E-03 0,03860681 ! formation of primary germ layer GO:0001704 14 14 1,000 2,87E-03 0,03832705 GO:0001707|mesoderm formation, ! DNA modification GO:0006304 14 14 1,000 2,87E-03 0,03805131 ! positive regulation of osteoblast differentiation GO:0045669 14 14 1,000 2,87E-03 0,03777952 ! anterior/posterior pattern formation GO:0009952 51 50 2,000 2,954E-03 0,03860697 ! rRNA metabolic process GO:0016072 51 51 2,000 3,126E-03 0,04056794 GO:0006364|rRNA processing, ! positive regulation of ossification GO:0045778 15 15 1,000 3,299E-03 0,04252072 GO:0046852|positive regulation of bone remodeling, GO:0034105|positive regulation of tissue remodeling, ! regulation of transcription factor import into nucleus GO:0042990 15 15 1,000 3,299E-03 0,04222544 ! insulin receptor signaling pathway GO:0008286 17 15 1,000 3,299E-03 0,04193423 ! ER-nuclear signaling pathway GO:0006984 15 15 1,000 3,299E-03 0,04164701 ! mesoderm morphogenesis GO:0048332 15 15 1,000 3,299E-03 0,04136369 ! hydrogen peroxide metabolic process GO:0042743 15 15 1,000 3,299E-03 0,04108421 ! regulation of biomineral formation GO:0070167 15 15 1,000 3,299E-03 0,04080848 GO:0030500|regulation of bone mineralization, ! negative regulation of cell activation GO:0050866 15 15 1,000 3,299E-03 0,04053642 ! protein homooligomerization GO:0051260 15 15 1,000 3,299E-03 0,04026797 ! response to light stimulus GO:0009416 53 52 2,000 3,304E-03 0,04005831 ! response to hypoxia GO:0001666 53 53 2,000 3,488E-03 0,04201542 ! response to oxygen levels GO:0070482 55 54 2,000 3,678E-03 0,04402115 ! negative regulation of multicellular organismal process GO:0051241 55 54 2,000 3,678E-03 0,04373714 ! regulation of synaptic plasticity GO:0048167 16 16 1,000 3,757E-03 0,0443822 ! segmentation GO:0035282 17 16 1,000 3,757E-03 0,04409951 ! regulation of systemic arterial blood pressure GO:0003073 17 16 1,000 3,757E-03 0,0438204 ! serine family amino acid metabolic process GO:0009069 16 16 1,000 3,757E-03 0,0435448 ! positive regulation of catabolic process GO:0009896 16 16 1,000 3,757E-03 0,04327265 ! regulation of cell morphogenesis involved in differentiation GO:0010769 17 16 1,000 3,757E-03 0,04300387 ! regulation of cell adhesion GO:0030155 56 55 2,000 3,875E-03 0,04408441 ! regulation of smooth muscle cell proliferation GO:0048660 17 17 1,000 4,242E-03 0,04796329 ! positive regulation of cell adhesion GO:0045785 17 17 1,000 4,242E-03 0,04767083 ! myelination GO:0042552 17 17 1,000 4,242E-03 0,04738192 ! glucose transport GO:0015758 17 17 1,000 4,242E-03 0,04709649 ! cell junction assembly GO:0034329 18 17 1,000 4,242E-03 0,04681447 ! tissue remodeling GO:0048771 17 17 1,000 4,242E-03 0,04653581 ! negative regulation of cell development GO:0010721 18 17 1,000 4,242E-03 0,04626045 GO:0050768|negative regulation of neurogenesis, ! regulation of oxidoreductase activity GO:0051341 17 17 1,000 4,242E-03 0,04598833 ! regulation of osteoblast differentiation GO:0045667 17 17 1,000 4,242E-03 0,04571939 ! peptidyl-amino acid modification GO:0018193 61 59 2,000 4,725E-03 0,05063279 ! regulation of cell projection organization GO:0031344 19 18 1,000 4,755E-03 0,05065345 ! epidermal growth factor receptor signaling pathway GO:0007173 18 18 1,000 4,755E-03 0,05036234 ! hexose transport GO:0008645 18 18 1,000 4,755E-03 0,05007455 GO:0015749|monosaccharide transport, ! hexose biosynthetic process GO:0019319 18 18 1,000 4,755E-03 0,04979004 ! ensheathment of neurons GO:0007272 18 18 1,000 4,755E-03 0,04950874 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 18 18 1,000 4,755E-03 0,0492306 ! regulation of endothelial cell proliferation GO:0001936 19 19 1,000 5,295E-03 0,05451467 ! metanephros development GO:0001656 19 19 1,000 5,295E-03 0,05421181 ! peripheral nervous system development GO:0007422 19 19 1,000 5,295E-03 0,0539123 ! regulation of cell shape GO:0008360 21 19 1,000 5,295E-03 0,05361608 ! chromatin remodeling GO:0006338 20 20 1,000 5,861E-03 0,05903099 ! monosaccharide biosynthetic process GO:0046364 20 20 1,000 5,861E-03 0,05871017 ! angiogenesis GO:0001525 65 64 2,000 5,936E-03 0,05913572 ! G1/S transition of mitotic cell cycle GO:0000082 21 21 1,000 6,455E-03 0,06395753 ! mammary gland development GO:0030879 23 21 1,000 6,455E-03 0,06361551 ! regulation of protein import into nucleus GO:0042306 21 21 1,000 6,455E-03 0,06327713 ! regulation of action potential in neuron GO:0019228 21 21 1,000 6,455E-03 0,06294233 ! cellular response to insulin stimulus GO:0032869 23 21 1,000 6,455E-03 0,06261105 ! negative regulation of protein transport GO:0051224 21 21 1,000 6,455E-03 0,06228325 ! regulation of MAP kinase activity GO:0043405 67 66 2,000 6,468E-03 0,06208251 ! striated muscle tissue development GO:0014706 69 67 2,000 6,744E-03 0,0643977 ! negative regulation of cell differentiation GO:0045596 68 67 2,000 6,744E-03 0,06406575 ! response to radiation GO:0009314 70 68 2,000 7,027E-03 0,06641272 ! positive regulation of transcription factor activity GO:0051091 22 22 1,000 7,074E-03 0,06651959 GO:0090047|positive regulation of transcription regulator activity, ! cell junction organization GO:0034330 23 22 1,000 7,074E-03 0,06618193 ! biopolymer methylation GO:0043414 22 22 1,000 7,074E-03 0,06584768 GO:0032259|methylation, ! response to nutrient levels GO:0031667 69 69 2,000 7,317E-03 0,0677643 ! positive regulation of transport GO:0051050 71 70 2,000 7,614E-03 0,07016339 ! muscle tissue development GO:0060537 72 70 2,000 7,614E-03 0,06981432 ! response to hydrogen peroxide GO:0042542 24 23 1,000 7,72E-03 0,07043228 ! viral infectious cycle GO:0019058 23 23 1,000 7,72E-03 0,07008533 ! endocrine system development GO:0035270 23 23 1,000 7,72E-03 0,06974177 ! calcium-mediated signaling GO:0019722 23 23 1,000 7,72E-03 0,06940157 ! cell projection assembly GO:0030031 25 23 1,000 7,72E-03 0,06906467 ! translational elongation GO:0006414 71 71 2,000 7,918E-03 0,07049905 ! ribosome biogenesis GO:0042254 71 71 2,000 7,918E-03 0,07016011 ! response to extracellular stimulus GO:0009991 72 72 2,000 8,23E-03 0,07256959 ! regulation of action potential GO:0001508 24 24 1,000 8,391E-03 0,07363799 ! cellular amino acid biosynthetic process GO:0008652 24 24 1,000 8,391E-03 0,073289 ! androgen receptor signaling pathway GO:0030521 24 24 1,000 8,391E-03 0,07294329 ! epithelial tube morphogenesis GO:0060562 25 24 1,000 8,391E-03 0,07260084 ! glucan metabolic process GO:0044042 25 24 1,000 8,391E-03 0,07226158 GO:0006073|cellular glucan metabolic process, GO:0005977|glycogen metabolic process, ! alcohol biosynthetic process GO:0046165 25 25 1,000 9,087E-03 0,07789419 ! regulation of T cell proliferation GO:0042129 25 25 1,000 9,087E-03 0,07753357 ! positive regulation of DNA binding GO:0043388 26 25 1,000 9,087E-03 0,07717627 ! gastrulation GO:0007369 25 25 1,000 9,087E-03 0,07682225 ! negative regulation of immune system process GO:0002683 25 25 1,000 9,087E-03 0,07647147 ! response to oxidative stress GO:0006979 76 75 2,000 9,207E-03 0,07712566 ! positive regulation of binding GO:0051099 27 26 1,000 9,808E-03 0,08179449 ! glycolysis GO:0006096 26 26 1,000 9,808E-03 0,08142605 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 26 26 1,000 9,808E-03 0,08106091 ! negative regulation of cell migration GO:0030336 26 26 1,000 9,808E-03 0,08069903 ! regulation of T cell differentiation GO:0045580 26 26 1,000 9,808E-03 0,08034037 ! response to insulin stimulus GO:0032868 28 26 1,000 9,808E-03 0,07998488 ! synapse organization GO:0050808 26 26 1,000 9,808E-03 0,07963252 ! cell morphogenesis involved in differentiation GO:0000904 82 77 2,000 9,894E-03 0,07997738 ! energy reserve metabolic process GO:0006112 28 27 1,000 0,01055422 0,08494071 ! mesenchymal cell development GO:0014031 29 27 1,000 0,01055422 0,08457141 GO:0060485|mesenchyme development, GO:0048762|mesenchymal cell differentiation, ! tRNA aminoacylation for protein translation GO:0006418 28 28 1,000 0,01132459 0,09035163 GO:0043038|amino acid activation, GO:0043039|tRNA aminoacylation, ! carbohydrate transport GO:0008643 28 28 1,000 0,01132459 0,08996218 ! histone modification GO:0016570 28 28 1,000 0,01132459 0,08957608 ! regulation of mast cell proliferation GO:0070666 28 28 1,000 0,01132459 0,08919327 ! positive regulation of cell cycle GO:0045787 29 29 1,000 0,01211907 0,09504446 ! viral reproductive process GO:0022415 29 29 1,000 0,01211907 0,09464173 ! branching morphogenesis of a tube GO:0048754 29 29 1,000 0,01211907 0,09424239 ! regulation of lymphocyte proliferation GO:0050670 29 29 1,000 0,01211907 0,09384642 GO:0032944|regulation of mononuclear cell proliferation, GO:0070663|regulation of leukocyte proliferation, ! regulation of gene expression, epigenetic GO:0040029 29 29 1,000 0,01211907 0,09345376 ! covalent chromatin modification GO:0016569 29 29 1,000 0,01211907 0,09306436 ! response to UV GO:0009411 29 29 1,000 0,01211907 0,09267821 ! ncRNA processing GO:0034470 83 83 2,000 0,01213355 0,09240552 ! blood vessel morphogenesis GO:0048514 84 83 2,000 0,01213355 0,09202525 ! activation of phospholipase C activity GO:0007202 30 30 1,000 0,01293736 0,09771947 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of response to external stimulus GO:0032103 30 30 1,000 0,01293736 0,09732062 ! regulation of ossification GO:0030278 30 30 1,000 0,01293736 0,09692501 ! vascular process in circulatory system GO:0003018 31 30 1,000 0,01293736 0,0965326 ! positive regulation of protein kinase activity GO:0045860 89 86 2,000 0,01335402 0,09923973 ! heart development GO:0007507 90 87 2,000 0,01377592 0,10196395 ! skeletal muscle fiber development GO:0048741 31 31 1,000 0,01377917 0,10158002 ! membrane fusion GO:0006944 31 31 1,000 0,01377917 0,10117532 ! positive regulation of phospholipase activity GO:0010518 31 31 1,000 0,01377917 0,10077383 ! regulation of myeloid cell differentiation GO:0045637 32 31 1,000 0,01377917 0,10037551 ! negative regulation of cell motion GO:0051271 31 31 1,000 0,01377917 0,09998033 ! positive regulation of transferase activity GO:0051347 91 88 2,000 0,0142054 0,10266883 GO:0033674|positive regulation of kinase activity, ! regulation of phospholipase activity GO:0010517 32 32 1,000 0,01464421 0,10542687 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 32 32 1,000 0,01464421 0,10501664 ! morphogenesis of a branching structure GO:0001763 32 32 1,000 0,01464421 0,1046096 ! muscle fiber development GO:0048747 32 32 1,000 0,01464421 0,1042057 ! glucose catabolic process GO:0006007 32 32 1,000 0,01464421 0,10380491 ! regulation of lymphocyte differentiation GO:0045619 32 32 1,000 0,01464421 0,10340719 ! kidney development GO:0001822 32 32 1,000 0,01464421 0,10301251 ! positive regulation of lipase activity GO:0060193 32 32 1,000 0,01464421 0,10262083 ! regulation of neuron differentiation GO:0045664 34 33 1,000 0,0155322 0,10843124 ! regulation of synaptic transmission GO:0050804 33 33 1,000 0,0155322 0,10802206 ! cellular polysaccharide metabolic process GO:0044264 35 34 1,000 0,01644286 0,11392554 ! regulation of protein catabolic process GO:0042176 35 34 1,000 0,01644286 0,11349885 ! response to peptide hormone stimulus GO:0043434 36 34 1,000 0,01644286 0,11307534 ! viral reproduction GO:0016032 34 34 1,000 0,01644286 0,11265499 ! tissue morphogenesis GO:0048729 94 93 2,000 0,01646704 0,1124028 ! regulation of cyclin-dependent protein kinase activity GO:0000079 35 35 1,000 0,01737591 0,118169 ! positive regulation of phosphorylation GO:0042327 35 35 1,000 0,01737591 0,11773455 ! oxygen and reactive oxygen species metabolic process GO:0006800 37 36 1,000 0,01833107 0,12375148 ! embryonic limb morphogenesis GO:0030326 36 36 1,000 0,01833107 0,12329983 GO:0035113|embryonic appendage morphogenesis, ! positive regulation of phosphorus metabolic process GO:0010562 36 36 1,000 0,01833107 0,12285147 GO:0045937|positive regulation of phosphate metabolic process, ! RNA elongation from RNA polymerase II promoter GO:0006368 36 36 1,000 0,01833107 0,12240636 ! regulation of transmission of nerve impulse GO:0051969 36 36 1,000 0,01833107 0,12196446 ! regulation of lipase activity GO:0060191 36 36 1,000 0,01833107 0,12152573 ! blood circulation GO:0008015 99 98 2,000 0,01892043 0,12498335 GO:0003013|circulatory system process, ! regulation of system process GO:0044057 98 98 2,000 0,01892043 0,12453698 ! regulation of transcription factor activity GO:0051090 38 37 1,000 0,01930806 0,12663613 GO:0090046|regulation of transcription regulator activity, ! response to drug GO:0042493 37 37 1,000 0,01930806 0,12618707 ! adaptive immune response GO:0002250 37 37 1,000 0,01930806 0,12574117 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! muscle organ development GO:0007517 102 100 2,000 0,0199558 0,12950187 ! cellular hormone metabolic process GO:0034754 39 38 1,000 0,02030661 0,13131611 ! urogenital system development GO:0001655 38 38 1,000 0,02030661 0,13085696 ! hexose catabolic process GO:0019320 38 38 1,000 0,02030661 0,13040101 ! RNA elongation GO:0006354 38 38 1,000 0,02030661 0,12994823 ! axon guidance GO:0007411 39 38 1,000 0,02030661 0,12949858 ! regulation of neurological system process GO:0031644 38 38 1,000 0,02030661 0,12905204 ! intracellular protein transmembrane transport GO:0065002 39 39 1,000 0,02132646 0,1350676 ! limb development GO:0060173 39 39 1,000 0,02132646 0,13460504 GO:0048736|appendage development, GO:0035107|appendage morphogenesis, ! protein oligomerization GO:0051259 39 39 1,000 0,02132646 0,13414563 ! regulation of caspase activity GO:0043281 41 41 1,000 0,02342896 0,14686932 ! monosaccharide catabolic process GO:0046365 41 41 1,000 0,02342896 0,14637146 ! regulation of endopeptidase activity GO:0052548 42 42 1,000 0,02451109 0,15261465 ! protein ubiquitination GO:0016567 43 42 1,000 0,02451109 0,1521008 ! one-carbon metabolic process GO:0006730 42 42 1,000 0,02451109 0,15159039 ! alcohol catabolic process GO:0046164 43 43 1,000 0,02561345 0,1578782 ! mRNA transport GO:0051028 44 44 1,000 0,02673578 0,1642468 ! protein import into nucleus GO:0006606 44 44 1,000 0,02673578 0,16370113 ! amine biosynthetic process GO:0009309 46 45 1,000 0,02787783 0,17012859 ! homophilic cell adhesion GO:0007156 45 45 1,000 0,02787783 0,16956711 ! regulation of DNA binding GO:0051101 47 45 1,000 0,02787783 0,16900932 ! phosphoinositide-mediated signaling GO:0048015 45 45 1,000 0,02787783 0,16845519 ! nuclear import GO:0051170 45 45 1,000 0,02787783 0,16790469 ! rRNA transcription GO:0009303 5 5 0,000 0,02874197 0,17254542 ! positive regulation of protein ubiquitination GO:0031398 5 5 0,000 0,02874197 0,1719852 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 5 5 0,000 0,02874197 0,17142862 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 5 5 0,000 0,02874197 0,17087562 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! neuron fate specification GO:0048665 5 5 0,000 0,02874197 0,17032618 ! hemoglobin biosynthetic process GO:0042541 5 5 0,000 0,02874197 0,16978027 ! reproductive cellular process GO:0048610 5 5 0,000 0,02874197 0,16923784 ! positive regulation of glucose metabolic process GO:0010907 5 5 0,000 0,02874197 0,16869886 ! prostate gland development GO:0030850 5 5 0,000 0,02874197 0,16816331 ! metencephalon development GO:0022037 5 5 0,000 0,02874197 0,16763115 ! water transport GO:0006833 5 5 0,000 0,02874197 0,16710234 GO:0042044|fluid transport, ! forebrain regionalization GO:0021871 5 5 0,000 0,02874197 0,16657686 ! DNA synthesis during DNA repair GO:0000731 5 5 0,000 0,02874197 0,16605468 ! positive regulation of B cell proliferation GO:0030890 5 5 0,000 0,02874197 0,16553576 ! glycerol metabolic process GO:0006071 5 5 0,000 0,02874197 0,16502007 ! regulation of cellular amine metabolic process GO:0033238 5 5 0,000 0,02874197 0,16450759 GO:0042053|regulation of dopamine metabolic process, GO:0042069|regulation of catecholamine metabolic process, ! meiotic prophase I GO:0007128 5 5 0,000 0,02874197 0,16399827 GO:0051324|prophase, ! cell volume homeostasis GO:0006884 5 5 0,000 0,02874197 0,16349211 ! regulation of epidermal growth factor receptor activity GO:0007176 5 5 0,000 0,02874197 0,16298905 GO:0010469|regulation of receptor activity, ! regulation of long-term neuronal synaptic plasticity GO:0048169 5 5 0,000 0,02874197 0,16248909 ! filopodium assembly GO:0046847 7 5 0,000 0,02874197 0,16199218 GO:0030035|microspike assembly, ! CTP metabolic process GO:0046036 5 5 0,000 0,02874197 0,1614983 GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0006241|CTP biosynthetic process, ! Golgi to endosome transport GO:0006895 5 5 0,000 0,02874197 0,16100742 ! GTP metabolic process GO:0046039 5 5 0,000 0,02874197 0,16051952 ! establishment of tissue polarity GO:0007164 5 5 0,000 0,02874197 0,16003457 ! positive regulation of cell-cell adhesion GO:0022409 5 5 0,000 0,02874197 0,15955254 ! regulation of neurotransmitter secretion GO:0046928 5 5 0,000 0,02874197 0,1590734 GO:0001956|positive regulation of neurotransmitter secretion, ! neurotransmitter uptake GO:0001504 5 5 0,000 0,02874197 0,15859713 ! social behavior GO:0035176 5 5 0,000 0,02874197 0,15812371 ! macrophage chemotaxis GO:0048246 6 5 0,000 0,02874197 0,1576531 ! 2-oxoglutarate metabolic process GO:0006103 5 5 0,000 0,02874197 0,15718529 ! memory GO:0007613 5 5 0,000 0,02874197 0,15672024 ! dopamine receptor signaling pathway GO:0007212 5 5 0,000 0,02874197 0,15625794 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 5 5 0,000 0,02874197 0,15579836 ! membrane hyperpolarization GO:0060081 5 5 0,000 0,02874197 0,15534147 ! response to lipid GO:0033993 5 5 0,000 0,02874197 0,15488726 ! erythrocyte maturation GO:0043249 5 5 0,000 0,02874197 0,15443569 ! hippocampus development GO:0021766 6 5 0,000 0,02874197 0,15398675 ! regulation of carbohydrate biosynthetic process GO:0043255 5 5 0,000 0,02874197 0,15354041 ! middle ear morphogenesis GO:0042474 5 5 0,000 0,02874197 0,15309666 ! amyloid precursor protein catabolic process GO:0042987 5 5 0,000 0,02874197 0,15265545 ! mechanosensory behavior GO:0007638 5 5 0,000 0,02874197 0,15221679 ! heart looping GO:0001947 5 5 0,000 0,02874197 0,15178064 ! negative regulation of endocytosis GO:0045806 5 5 0,000 0,02874197 0,15134698 ! response to interferon-gamma GO:0034341 5 5 0,000 0,02874197 0,15091579 ! pseudouridine synthesis GO:0001522 5 5 0,000 0,02874197 0,15048705 ! pH reduction GO:0045851 5 5 0,000 0,02874197 0,15006074 GO:0051452|intracellular pH reduction, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 5 5 0,000 0,02874197 0,14963684 ! lipopolysaccharide metabolic process GO:0008653 5 5 0,000 0,02874197 0,14921533 ! positive regulation of chemokine biosynthetic process GO:0045080 5 5 0,000 0,02874197 0,14879619 ! sphingoid biosynthetic process GO:0046520 5 5 0,000 0,02874197 0,14837939 GO:0046513|ceramide biosynthetic process, ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 5 5 0,000 0,02874197 0,14796492 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! thymic T cell selection GO:0045061 5 5 0,000 0,02874197 0,14755277 ! insulin-like growth factor receptor signaling pathway GO:0048009 5 5 0,000 0,02874197 0,1471429 ! photoreceptor cell maintenance GO:0045494 5 5 0,000 0,02874197 0,1467353 ! adrenal gland development GO:0030325 5 5 0,000 0,02874197 0,14632995 ! regulation of cardiac muscle hypertrophy GO:0010611 5 5 0,000 0,02874197 0,14592684 GO:0010612|regulation of cardiac muscle adaptation, GO:0014743|regulation of muscle hypertrophy, GO:0043502|regulation of muscle adaptation, ! melanocyte differentiation GO:0030318 5 5 0,000 0,02874197 0,14552594 GO:0050931|pigment cell differentiation, ! ovulation GO:0030728 5 5 0,000 0,02874197 0,14512724 ! astrocyte differentiation GO:0048708 5 5 0,000 0,02874197 0,14473072 ! mitochondrial respiratory chain complex assembly GO:0033108 5 5 0,000 0,02874197 0,14433636 GO:0032981|mitochondrial respiratory chain complex I assembly, GO:0010257|NADH dehydrogenase complex assembly, ! pituitary gland development GO:0021983 5 5 0,000 0,02874197 0,14394414 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 5 5 0,000 0,02874197 0,14355405 GO:0033135|regulation of peptidyl-serine phosphorylation, ! tyrosine metabolic process GO:0006570 5 5 0,000 0,02874197 0,14316606 ! cytoskeletal anchoring at plasma membrane GO:0007016 6 5 0,000 0,02874197 0,14278017 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 5 5 0,000 0,02874197 0,14239635 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, GO:0009164|nucleoside catabolic process, ! microtubule nucleation GO:0007020 5 5 0,000 0,02874197 0,14201459 ! regulation of interleukin-6 biosynthetic process GO:0045408 5 5 0,000 0,02874197 0,14163487 ! regulation of interleukin-8 biosynthetic process GO:0045414 5 5 0,000 0,02874197 0,14125718 ! indolalkylamine metabolic process GO:0006586 5 5 0,000 0,02874197 0,1408815 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! muscle cell migration GO:0014812 5 5 0,000 0,02874197 0,14050781 ! phasic smooth muscle contraction GO:0014821 5 5 0,000 0,02874197 0,14013609 ! central nervous system neuron axonogenesis GO:0021955 6 5 0,000 0,02874197 0,13976634 GO:0021952|central nervous system projection neuron axonogenesis, ! sister chromatid cohesion GO:0007062 5 5 0,000 0,02874197 0,13939853 ! response to ATP GO:0033198 5 5 0,000 0,02874197 0,13903266 ! regulation of type I interferon production GO:0032479 5 5 0,000 0,02874197 0,1386687 ! regulation of appetite GO:0032098 5 5 0,000 0,02874197 0,13830664 GO:0032095|regulation of response to food, ! vesicle fusion GO:0006906 5 5 0,000 0,02874197 0,13794647 ! paraxial mesoderm development GO:0048339 5 5 0,000 0,02874197 0,13758816 ! regulation of the force of heart contraction GO:0002026 5 5 0,000 0,02874197 0,13723172 ! maintenance of protein location in nucleus GO:0051457 5 5 0,000 0,02874197 0,13687711 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,02874197 0,13652434 ! receptor clustering GO:0043113 5 5 0,000 0,02874197 0,13617337 ! neurotransmitter biosynthetic process GO:0042136 6 5 0,000 0,02874197 0,13582421 ! fear response GO:0042596 5 5 0,000 0,02874197 0,13547684 ! actin cytoskeleton reorganization GO:0031532 5 5 0,000 0,02874197 0,13513123 ! lens development in camera-type eye GO:0002088 5 5 0,000 0,02874197 0,13478739 ! retinol metabolic process GO:0042572 5 5 0,000 0,02874197 0,13444529 ! temperature homeostasis GO:0001659 5 5 0,000 0,02874197 0,13410492 ! positive regulation of exocytosis GO:0045921 6 5 0,000 0,02874197 0,13376627 ! parturition GO:0007567 5 5 0,000 0,02874197 0,13342933 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,02874197 0,13309408 ! regulation of vascular endothelial growth factor production GO:0010574 5 5 0,000 0,02874197 0,13276051 ! Schwann cell differentiation GO:0014037 5 5 0,000 0,02874197 0,13242861 ! acyl-CoA metabolic process GO:0006637 5 5 0,000 0,02874197 0,13209836 ! wound healing, spreading of epidermal cells GO:0035313 5 5 0,000 0,02874197 0,13176976 ! protein heterooligomerization GO:0051291 5 5 0,000 0,02874197 0,13144279 ! regulation of gliogenesis GO:0014013 5 5 0,000 0,02874197 0,13111743 GO:0045685|regulation of glial cell differentiation, ! positive regulation of peptide secretion GO:0002793 5 5 0,000 0,02874197 0,13079369 ! response to UV-B GO:0010224 5 5 0,000 0,02874197 0,13047153 ! oligodendrocyte development GO:0014003 5 5 0,000 0,02874197 0,13015097 ! hyaluronan metabolic process GO:0030212 5 5 0,000 0,02874197 0,12983197 ! activated T cell proliferation GO:0050798 5 5 0,000 0,02874197 0,12951453 ! interaction with symbiont GO:0051702 5 5 0,000 0,02874197 0,12919864 ! cellular extravasation GO:0045123 5 5 0,000 0,02874197 0,12888429 ! positive regulation of axonogenesis GO:0050772 5 5 0,000 0,02874197 0,12857146 ! peptidyl-asparagine modification GO:0018196 5 5 0,000 0,02874197 0,12826015 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! positive regulation of phagocytosis GO:0050766 5 5 0,000 0,02874197 0,12795034 ! regulation of insulin receptor signaling pathway GO:0046626 5 5 0,000 0,02874197 0,12764203 ! antigen processing and presentation of exogenous antigen GO:0019884 5 5 0,000 0,02874197 0,1273352 ! enucleate erythrocyte differentiation GO:0043353 6 5 0,000 0,02874197 0,12702984 ! response to amine stimulus GO:0014075 5 5 0,000 0,02874197 0,12672594 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 5 5 0,000 0,02874197 0,12642349 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 5 5 0,000 0,02874197 0,12612248 ! synaptic vesicle exocytosis GO:0016079 6 5 0,000 0,02874197 0,1258229 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 5 5 0,000 0,02874197 0,12552475 ! glycosylceramide metabolic process GO:0006677 5 5 0,000 0,02874197 0,125228 ! neuron recognition GO:0008038 5 5 0,000 0,02874197 0,12493265 ! negative regulation of focal adhesion formation GO:0051895 6 5 0,000 0,02874197 0,12463869 ! decidualization GO:0046697 5 5 0,000 0,02874197 0,12434611 ! hair follicle maturation GO:0048820 5 5 0,000 0,02874197 0,1240549 ! phosphatidylinositol biosynthetic process GO:0006661 5 5 0,000 0,02874197 0,12376505 ! regulation of mitochondrial membrane potential GO:0051881 5 5 0,000 0,02874197 0,12347656 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 0,02874197 0,1231894 GO:0009155|purine deoxyribonucleotide catabolic process, ! regulation of interleukin-12 production GO:0032655 5 5 0,000 0,02874197 0,12290358 ! positive regulation of interleukin-6 production GO:0032755 5 5 0,000 0,02874197 0,12261908 ! positive regulation of monooxygenase activity GO:0032770 5 5 0,000 0,02874197 0,1223359 ! postreplication repair GO:0006301 5 5 0,000 0,02874197 0,12205402 ! spinal cord motor neuron differentiation GO:0021522 5 5 0,000 0,02874197 0,12177343 GO:0021517|ventral spinal cord development, ! cellular pigmentation GO:0033059 5 5 0,000 0,02874197 0,12149413 ! histone methylation GO:0016571 5 5 0,000 0,02874197 0,12121612 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,02874197 0,12093937 ! T cell lineage commitment GO:0002360 5 5 0,000 0,02874197 0,12066388 ! positive regulation of immunoglobulin mediated immune response GO:0002891 5 5 0,000 0,02874197 0,12038964 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of interferon-gamma production GO:0032729 5 5 0,000 0,02874197 0,12011665 ! negative regulation of tumor necrosis factor production GO:0032720 5 5 0,000 0,02874197 0,11984489 ! intracellular cholesterol transport GO:0032367 5 5 0,000 0,02874197 0,11957436 GO:0032366|intracellular sterol transport, ! regulation of mast cell activation GO:0033003 5 5 0,000 0,02874197 0,11930505 ! morphogenesis of a polarized epithelium GO:0001738 5 5 0,000 0,02874197 0,11903695 ! regulation of hormone metabolic process GO:0032350 5 5 0,000 0,02874197 0,11877005 ! regulation of transcription from RNA polymerase III promoter GO:0006359 5 5 0,000 0,02874197 0,11850435 ! regulation of inflammatory response to antigenic stimulus GO:0002861 5 5 0,000 0,02874197 0,11823983 ! sterol catabolic process GO:0016127 5 5 0,000 0,02874197 0,11797649 GO:0006707|cholesterol catabolic process, ! negative regulation of oxidoreductase activity GO:0051354 5 5 0,000 0,02874197 0,11771432 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 5 5 0,000 0,02874197 0,11745331 ! detection of biotic stimulus GO:0009595 5 5 0,000 0,02874197 0,11719346 ! regulation of immune response to tumor cell GO:0002837 5 5 0,000 0,02874197 0,11693475 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 5 5 0,000 0,02874197 0,11667719 ! zymogen activation GO:0031638 5 5 0,000 0,02874197 0,11642075 ! positive regulation of interleukin-1 beta secretion GO:0050718 5 5 0,000 0,02874197 0,11616544 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 5 5 0,000 0,02874197 0,11591125 GO:0002820|negative regulation of adaptive immune response, ! cellular response to nutrient GO:0031670 5 5 0,000 0,02874197 0,11565817 ! negative regulation of neuroblast proliferation GO:0007406 5 5 0,000 0,02874197 0,11540619 ! peptidyl-histidine modification GO:0018202 5 5 0,000 0,02874197 0,11515531 ! nucleosome positioning GO:0016584 5 5 0,000 0,02874197 0,11490552 ! regulation of isotype switching GO:0045191 5 5 0,000 0,02874197 0,1146568 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 5 5 0,000 0,02874197 0,11440916 ! negative regulation of neurological system process GO:0031645 5 5 0,000 0,02874197 0,11416259 ! regulation of myoblast differentiation GO:0045661 5 5 0,000 0,02874197 0,11391708 ! glutathione biosynthetic process GO:0006750 5 5 0,000 0,02874197 0,11367262 ! NADPH regeneration GO:0006740 5 5 0,000 0,02874197 0,11342921 GO:0006098|pentose-phosphate shunt, ! positive regulation of erythrocyte differentiation GO:0045648 5 5 0,000 0,02874197 0,11318684 ! positive regulation of epidermis development GO:0045684 5 5 0,000 0,02874197 0,11294551 ! positive regulation of leukocyte chemotaxis GO:0002690 5 5 0,000 0,02874197 0,1127052 GO:0002688|regulation of leukocyte chemotaxis, ! musculoskeletal movement GO:0050881 5 5 0,000 0,02874197 0,11246591 GO:0050879|multicellular organismal movement, ! neuromuscular process controlling posture GO:0050884 5 5 0,000 0,02874197 0,11222763 ! sarcomere organization GO:0045214 5 5 0,000 0,02874197 0,11199037 ! regulation of epidermal cell differentiation GO:0045604 5 5 0,000 0,02874197 0,1117541 ! activation of NF-kappaB-inducing kinase activity GO:0007250 5 5 0,000 0,02874197 0,11151883 ! negative regulation of glucose transport GO:0010829 5 5 0,000 0,02874197 0,11128454 GO:0046325|negative regulation of glucose import, ! positive regulation of T-helper cell differentiation GO:0045624 5 5 0,000 0,02874197 0,11105124 GO:0045622|regulation of T-helper cell differentiation, ! oocyte differentiation GO:0009994 5 5 0,000 0,02874197 0,11081892 GO:0048599|oocyte development, ! dopamine biosynthetic process GO:0042416 5 5 0,000 0,02874197 0,11058756 ! regulation of protein homodimerization activity GO:0043496 6 5 0,000 0,02874197 0,11035717 ! spleen development GO:0048536 5 5 0,000 0,02874197 0,11012774 ! male genitalia development GO:0030539 5 5 0,000 0,02874197 0,10989926 ! nicotinamide nucleotide biosynthetic process GO:0019359 5 5 0,000 0,02874197 0,10967172 ! quaternary ammonium group transport GO:0015697 5 5 0,000 0,02874197 0,10944513 ! thyroid hormone metabolic process GO:0042403 5 5 0,000 0,02874197 0,10921947 ! leukocyte mediated cytotoxicity GO:0001909 5 5 0,000 0,02874197 0,10899474 ! positive regulation of viral reproduction GO:0048524 5 5 0,000 0,02874197 0,10877093 ! removal of superoxide radicals GO:0019430 6 5 0,000 0,02874197 0,10854804 ! myeloid cell homeostasis GO:0002262 5 5 0,000 0,02874197 0,10832606 ! regulation of fatty acid oxidation GO:0046320 5 5 0,000 0,02874197 0,10810499 ! regulation of Rac protein signal transduction GO:0035020 5 5 0,000 0,02874197 0,10788481 ! ATP catabolic process GO:0006200 5 5 0,000 0,02874197 0,10766553 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,02874197 0,10744715 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 5 5 0,000 0,02874197 0,10722964 ! blastocyst formation GO:0001825 5 5 0,000 0,02874197 0,10701302 ! regulation of fibrinolysis GO:0051917 5 5 0,000 0,02874197 0,10679726 ! embryonic gut development GO:0048566 5 5 0,000 0,02874197 0,10658238 ! negative regulation of organic acid transport GO:0032891 5 5 0,000 0,02874197 0,10636836 ! pyrimidine base metabolic process GO:0006206 5 5 0,000 0,02874197 0,1061552 ! activation of innate immune response GO:0002218 5 5 0,000 0,02874197 0,10594289 GO:0002758|innate immune response-activating signal transduction, ! catecholamine transport GO:0051937 5 5 0,000 0,02874197 0,10573142 ! negative regulation of blood vessel endothelial cell migration GO:0043537 5 5 0,000 0,02874197 0,1055208 ! regulation of NF-kappaB import into nucleus GO:0042345 5 5 0,000 0,02874197 0,10531102 ! muscle adaptation GO:0043500 5 5 0,000 0,02874197 0,10510207 ! positive regulation of actin filament bundle formation GO:0032233 5 5 0,000 0,02874197 0,10489395 ! embryonic heart tube development GO:0035050 5 5 0,000 0,02874197 0,10468665 ! cardiac cell differentiation GO:0035051 6 5 0,000 0,02874197 0,10448016 ! positive regulation of homeostatic process GO:0032846 5 5 0,000 0,02874197 0,10427449 ! defense response to fungus GO:0050832 5 5 0,000 0,02874197 0,10406963 ! lysogeny GO:0030069 5 5 0,000 0,02874197 0,10386557 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 5 5 0,000 0,02874197 0,10366231 ! B cell receptor signaling pathway GO:0050853 5 5 0,000 0,02874197 0,10345985 ! positive regulation of smooth muscle contraction GO:0045987 5 5 0,000 0,02874197 0,10325817 ! response to nicotine GO:0035094 5 5 0,000 0,02874197 0,10305728 ! establishment of cell polarity GO:0030010 5 5 0,000 0,02874197 0,10285717 ! mitochondrion localization GO:0051646 5 5 0,000 0,02874197 0,10265783 ! nucleus localization GO:0051647 5 5 0,000 0,02874197 0,10245927 ! regulation of synapse structure and activity GO:0050803 5 5 0,000 0,02874197 0,10226147 ! tube morphogenesis GO:0035239 47 46 1,000 0,02903934 0,10312042 ! regulation of peptidase activity GO:0052547 46 46 1,000 0,02903934 0,10292211 ! transcription initiation from RNA polymerase II promoter GO:0006367 46 46 1,000 0,02903934 0,10272456 ! cellular response to hormone stimulus GO:0032870 48 46 1,000 0,02903934 0,10252777 ! regulation of membrane potential GO:0042391 46 46 1,000 0,02903934 0,10233173 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 47 47 1,000 0,03022006 0,10628924 ! regulation of blood pressure GO:0008217 48 47 1,000 0,03022006 0,10608679 ! regulation of catabolic process GO:0009894 48 47 1,000 0,03022006 0,1058851 ! calcium ion transport GO:0006816 48 48 1,000 0,03141973 0,10987964 ! actin filament organization GO:0007015 50 48 1,000 0,03141973 0,10967153 ! protein localization in nucleus GO:0034504 48 48 1,000 0,03141973 0,10946422 ! ossification GO:0001503 50 49 1,000 0,03263812 0,11349445 GO:0060348|bone development, ! gland development GO:0048732 51 49 1,000 0,03263812 0,11328072 ! cell cycle arrest GO:0007050 49 49 1,000 0,03263812 0,11306778 ! cellular lipid catabolic process GO:0044242 50 49 1,000 0,03263812 0,11285565 ! divalent metal ion transport GO:0070838 49 49 1,000 0,03263812 0,11264431 ! negative regulation of transport GO:0051051 51 50 1,000 0,03387498 0,11669454 ! RNA transport GO:0050658 50 50 1,000 0,03387498 0,11647683 GO:0050657|nucleic acid transport, GO:0051236|establishment of RNA localization, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 50 50 1,000 0,03387498 0,11625993 ! regulation of neurogenesis GO:0050767 51 50 1,000 0,03387498 0,11604383 ! transcription initiation GO:0006352 50 50 1,000 0,03387498 0,11582854 ! anatomical structure homeostasis GO:0060249 51 50 1,000 0,03387498 0,11561404 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 6 6 0,000 0,03439292 0,1171648 ! axon extension GO:0048675 7 6 0,000 0,03439292 0,11694862 ! oligosaccharide biosynthetic process GO:0009312 6 6 0,000 0,03439292 0,11673325 ! tRNA modification GO:0006400 6 6 0,000 0,03439292 0,11651867 ! somatic diversification of immune receptors via somatic mutation GO:0002566 6 6 0,000 0,03439292 0,11630487 GO:0016446|somatic hypermutation of immunoglobulin genes, ! 'de novo' posttranslational protein folding GO:0051084 6 6 0,000 0,03439292 0,11609186 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 6 6 0,000 0,03439292 0,11587962 ! negative regulation of cellular catabolic process GO:0031330 6 6 0,000 0,03439292 0,11566816 ! virus-host interaction GO:0019048 6 6 0,000 0,03439292 0,11545748 ! regulation of S phase GO:0033261 6 6 0,000 0,03439292 0,11524755 ! myotube differentiation GO:0014902 6 6 0,000 0,03439292 0,11503839 ! regulation of B cell proliferation GO:0030888 6 6 0,000 0,03439292 0,11482999 ! bone remodeling GO:0046849 6 6 0,000 0,03439292 0,11462234 ! N-glycan processing GO:0006491 6 6 0,000 0,03439292 0,11441544 ! regulation of lipid kinase activity GO:0043550 6 6 0,000 0,03439292 0,11420929 ! glycosaminoglycan catabolic process GO:0006027 6 6 0,000 0,03439292 0,11400387 ! negative regulation of JAK-STAT cascade GO:0046426 6 6 0,000 0,03439292 0,1137992 ! retina development in camera-type eye GO:0060041 6 6 0,000 0,03439292 0,11359526 ! RNA methylation GO:0001510 6 6 0,000 0,03439292 0,11339205 ! cartilage condensation GO:0001502 7 6 0,000 0,03439292 0,11318956 ! regulation of activated T cell proliferation GO:0046006 6 6 0,000 0,03439292 0,1129878 ! succinate metabolic process GO:0006105 7 6 0,000 0,03439292 0,11278675 ! artery development GO:0060840 6 6 0,000 0,03439292 0,11258642 GO:0048844|artery morphogenesis, ! positive regulation of neurotransmitter transport GO:0051590 6 6 0,000 0,03439292 0,1123868 ! bile acid metabolic process GO:0008206 6 6 0,000 0,03439292 0,11218788 ! androgen metabolic process GO:0008209 6 6 0,000 0,03439292 0,11198967 ! estrogen metabolic process GO:0008210 6 6 0,000 0,03439292 0,11179216 ! limbic system development GO:0021761 7 6 0,000 0,03439292 0,11159534 ! cytoplasmic sequestering of transcription factor GO:0042994 6 6 0,000 0,03439292 0,11139922 ! positive regulation of heart contraction GO:0045823 6 6 0,000 0,03439292 0,11120378 ! positive regulation of gene expression, epigenetic GO:0045815 6 6 0,000 0,03439292 0,11100903 ! pathogenesis GO:0009405 6 6 0,000 0,03439292 0,11081496 ! negative regulation of protein amino acid phosphorylation GO:0001933 6 6 0,000 0,03439292 0,11062156 ! positive regulation of cell growth GO:0030307 6 6 0,000 0,03439292 0,11042884 ! ribonucleoside triphosphate catabolic process GO:0009203 6 6 0,000 0,03439292 0,11023679 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! regulation of chemokine biosynthetic process GO:0045073 6 6 0,000 0,03439292 0,11004541 ! nerve growth factor receptor signaling pathway GO:0048011 6 6 0,000 0,03439292 0,10985469 ! inositol phosphate-mediated signaling GO:0048016 6 6 0,000 0,03439292 0,10966463 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 6 6 0,000 0,03439292 0,10947522 ! arginine metabolic process GO:0006525 6 6 0,000 0,03439292 0,10928647 GO:0006527|arginine catabolic process, ! regulation of catecholamine secretion GO:0050433 6 6 0,000 0,03439292 0,10909837 ! oligodendrocyte differentiation GO:0048709 6 6 0,000 0,03439292 0,10891092 ! glutamate catabolic process GO:0006538 7 6 0,000 0,03439292 0,10872411 ! telomere maintenance via telomerase GO:0007004 6 6 0,000 0,03439292 0,10853794 GO:0010833|telomere maintenance via telomere lengthening, ! L-phenylalanine metabolic process GO:0006558 6 6 0,000 0,03439292 0,1083524 GO:0006559|L-phenylalanine catabolic process, ! glucan biosynthetic process GO:0009250 6 6 0,000 0,03439292 0,1081675 GO:0005978|glycogen biosynthetic process, ! V(D)J recombination GO:0033151 6 6 0,000 0,03439292 0,10798323 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 0,03439292 0,10779958 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 6 6 0,000 0,03439292 0,10761656 ! negative regulation of endothelial cell migration GO:0010596 6 6 0,000 0,03439292 0,10743416 ! regulation of heart rate GO:0002027 6 6 0,000 0,03439292 0,10725238 ! lipid digestion GO:0044241 6 6 0,000 0,03439292 0,10707121 ! asymmetric protein localization GO:0008105 6 6 0,000 0,03439292 0,10689065 ! retrograde transport, endosome to Golgi GO:0042147 6 6 0,000 0,03439292 0,1067107 ! phagocytosis, engulfment GO:0006911 6 6 0,000 0,03439292 0,10653135 ! Rac protein signal transduction GO:0016601 6 6 0,000 0,03439292 0,10635261 ! regulation of calcium ion transport into cytosol GO:0010522 6 6 0,000 0,03439292 0,10617446 ! ruffle organization GO:0031529 6 6 0,000 0,03439292 0,10599691 ! preassembly of GPI anchor in ER membrane GO:0016254 6 6 0,000 0,03439292 0,10581996 ! retinoic acid metabolic process GO:0042573 6 6 0,000 0,03439292 0,10564359 ! neutral amino acid transport GO:0015804 6 6 0,000 0,03439292 0,10546781 ! L-amino acid transport GO:0015807 6 6 0,000 0,03439292 0,10529262 ! bone mineralization GO:0030282 6 6 0,000 0,03439292 0,105118 GO:0031214|biomineral formation, ! rRNA modification GO:0000154 6 6 0,000 0,03439292 0,10494396 ! negative regulation of ossification GO:0030279 6 6 0,000 0,03439292 0,1047705 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 6 6 0,000 0,03439292 0,10459761 GO:0002717|positive regulation of natural killer cell mediated immunity, GO:0002715|regulation of natural killer cell mediated immunity, GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 7 6 0,000 0,03439292 0,1044253 ! purine base biosynthetic process GO:0009113 6 6 0,000 0,03439292 0,10425354 ! G1 DNA damage checkpoint GO:0031571 6 6 0,000 0,03439292 0,10408236 ! negative regulation of axonogenesis GO:0050771 7 6 0,000 0,03439292 0,10391173 ! regulation of phagocytosis GO:0050764 6 6 0,000 0,03439292 0,10374166 ! regulation of organ growth GO:0046620 6 6 0,000 0,03439292 0,10357215 ! regulation of circadian rhythm GO:0042752 6 6 0,000 0,03439292 0,10340319 ! positive regulation of T cell mediated immunity GO:0002711 6 6 0,000 0,03439292 0,10323478 ! response to dsRNA GO:0043331 6 6 0,000 0,03439292 0,10306692 ! DNA unwinding during replication GO:0006268 6 6 0,000 0,03439292 0,1028996 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 6 6 0,000 0,03439292 0,10273283 GO:0009147|pyrimidine nucleoside triphosphate metabolic process, ! genitalia development GO:0048806 6 6 0,000 0,03439292 0,10256659 ! sphingomyelin metabolic process GO:0006684 6 6 0,000 0,03439292 0,1024009 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 6 6 0,000 0,03439292 0,10223573 ! positive regulation of B cell differentiation GO:0045579 6 6 0,000 0,03439292 0,1020711 ! multicellular organismal aging GO:0010259 6 6 0,000 0,03439292 0,101907 ! regulation of focal adhesion formation GO:0051893 7 6 0,000 0,03439292 0,10174343 ! respiratory chain complex IV assembly GO:0008535 6 6 0,000 0,03439292 0,10158038 ! erythrocyte development GO:0048821 6 6 0,000 0,03439292 0,10141785 ! renal water homeostasis GO:0003091 6 6 0,000 0,03439292 0,10125584 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 6 6 0,000 0,03439292 0,10109435 GO:0043372|positive regulation of CD4-positive, alpha beta T cell differentiation, ! regulation of Rho GTPase activity GO:0032319 6 6 0,000 0,03439292 0,10093337 ! ribosome assembly GO:0042255 6 6 0,000 0,03439292 0,1007729 ! positive regulation of Ras GTPase activity GO:0032320 6 6 0,000 0,03439292 0,10061294 ! diencephalon development GO:0021536 6 6 0,000 0,03439292 0,10045349 ! fucose catabolic process GO:0019317 6 6 0,000 0,03439292 0,10029455 GO:0042355|L-fucose catabolic process, ! nitric oxide metabolic process GO:0046209 6 6 0,000 0,03439292 0,1001361 GO:0006809|nitric oxide biosynthetic process, ! regulation of lipid transport GO:0032368 6 6 0,000 0,03439292 0,09997816 ! regulation of cell division GO:0051302 6 6 0,000 0,03439292 0,09982072 ! positive regulation of interleukin-1 secretion GO:0050716 6 6 0,000 0,03439292 0,09966376 ! cellular metabolic compound salvage GO:0043094 6 6 0,000 0,03439292 0,09950731 ! regulation of T-helper 2 type immune response GO:0002828 6 6 0,000 0,03439292 0,09935134 ! salivary gland morphogenesis GO:0007435 6 6 0,000 0,03439292 0,09919586 ! neuroblast proliferation GO:0007405 6 6 0,000 0,03439292 0,09904087 ! regulation of interleukin-1 beta secretion GO:0050706 6 6 0,000 0,03439292 0,09888636 ! nitric oxide mediated signal transduction GO:0007263 6 6 0,000 0,03439292 0,09873233 ! regulation of glucose transport GO:0010827 6 6 0,000 0,03439292 0,09857878 GO:0046324|regulation of glucose import, ! intestinal absorption GO:0050892 6 6 0,000 0,03439292 0,09842571 ! methionine biosynthetic process GO:0009086 6 6 0,000 0,03439292 0,09827311 ! glutamine family amino acid biosynthetic process GO:0009084 6 6 0,000 0,03439292 0,09812098 ! thymus development GO:0048538 6 6 0,000 0,03439292 0,09796933 ! lymph node development GO:0048535 6 6 0,000 0,03439292 0,09781814 ! organic cation transport GO:0015695 6 6 0,000 0,03439292 0,09766742 ! regulation of RNA splicing GO:0043484 6 6 0,000 0,03439292 0,09751716 ! regulation of cellular carbohydrate catabolic process GO:0043471 6 6 0,000 0,03439292 0,09736736 GO:0043470|regulation of carbohydrate catabolic process, GO:0006110|regulation of glycolysis, ! positive regulation of JNK cascade GO:0046330 7 6 0,000 0,03439292 0,09721803 ! sperm-egg recognition GO:0035036 7 6 0,000 0,03439292 0,09706915 GO:0007339|binding of sperm to zona pellucida, ! germ cell migration GO:0008354 6 6 0,000 0,03439292 0,09692073 ! establishment or maintenance of apical/basal cell polarity GO:0035088 6 6 0,000 0,03439292 0,09677275 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 6 6 0,000 0,03439292 0,09662524 ! alditol metabolic process GO:0019400 6 6 0,000 0,03439292 0,09647816 ! regulation of synaptic transmission, GABAergic GO:0032228 6 6 0,000 0,03439292 0,09633154 ! regulation of amino acid transport GO:0051955 6 6 0,000 0,03439292 0,09618536 ! maternal placenta development GO:0001893 6 6 0,000 0,03439292 0,09603963 ! negative regulation of immune effector process GO:0002698 6 6 0,000 0,03439292 0,09589433 ! interphase of mitotic cell cycle GO:0051329 52 51 1,000 0,03513005 0,09780163 GO:0051325|interphase, ! RNA localization GO:0006403 52 52 1,000 0,0364031 0,10119293 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 52 52 1,000 0,0364031 0,10104053 ! tRNA metabolic process GO:0006399 53 53 1,000 0,03769389 0,10446592 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 53 53 1,000 0,03769389 0,10430906 ! carbohydrate biosynthetic process GO:0016051 53 53 1,000 0,03769389 0,10415268 ! carbohydrate catabolic process GO:0016052 53 53 1,000 0,03769389 0,10399676 ! regulation of T cell activation GO:0050863 53 53 1,000 0,03769389 0,10384131 ! hormone metabolic process GO:0042445 55 54 1,000 0,03900218 0,10728509 ! respiratory burst GO:0045730 7 7 0,000 0,04001182 0,10989833 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 7 7 0,000 0,04001182 0,10973479 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 7 7 0,000 0,04001182 0,10957173 ! positive regulation of blood pressure GO:0045777 7 7 0,000 0,04001182 0,10940917 ! positive regulation of cellular catabolic process GO:0031331 7 7 0,000 0,04001182 0,10924708 ! pteridine and derivative biosynthetic process GO:0042559 7 7 0,000 0,04001182 0,10908547 ! regulation of chemokine production GO:0032642 7 7 0,000 0,04001182 0,10892434 ! double-strand break repair via homologous recombination GO:0000724 7 7 0,000 0,04001182 0,10876368 GO:0000725|recombinational repair, ! positive regulation of GTPase activity GO:0043547 7 7 0,000 0,04001182 0,1086035 ! SMAD protein nuclear translocation GO:0007184 7 7 0,000 0,04001182 0,10844379 ! cellular protein complex disassembly GO:0043624 8 7 0,000 0,04001182 0,10828455 GO:0043241|protein complex disassembly, ! hair follicle morphogenesis GO:0031069 7 7 0,000 0,04001182 0,10812577 ! gene silencing by RNA GO:0031047 7 7 0,000 0,04001182 0,10796746 ! regulation of receptor-mediated endocytosis GO:0048259 7 7 0,000 0,04001182 0,10780962 ! oxaloacetate metabolic process GO:0006107 7 7 0,000 0,04001182 0,10765223 ! regulation of neurotransmitter transport GO:0051588 7 7 0,000 0,04001182 0,1074953 ! keratinocyte proliferation GO:0043616 7 7 0,000 0,04001182 0,10733883 ! axis specification GO:0009798 7 7 0,000 0,04001182 0,10718282 ! negative regulation of muscle cell differentiation GO:0051148 7 7 0,000 0,04001182 0,10702725 ! visual behavior GO:0007632 7 7 0,000 0,04001182 0,10687214 GO:0008542|visual learning, ! startle response GO:0001964 7 7 0,000 0,04001182 0,10671748 ! amyloid precursor protein metabolic process GO:0042982 7 7 0,000 0,04001182 0,10656326 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 8 7 0,000 0,04001182 0,10640949 ! positive regulation of lipid metabolic process GO:0045834 7 7 0,000 0,04001182 0,10625616 ! negative regulation of lipid metabolic process GO:0045833 7 7 0,000 0,04001182 0,10610328 ! regulation of interferon-gamma biosynthetic process GO:0045072 7 7 0,000 0,04001182 0,10595083 ! endothelial cell differentiation GO:0045446 7 7 0,000 0,04001182 0,10579882 ! negative regulation of striated muscle development GO:0045843 7 7 0,000 0,04001182 0,10564725 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 7 7 0,000 0,04001182 0,10549611 ! digestive system development GO:0055123 7 7 0,000 0,04001182 0,1053454 GO:0048546|digestive tract morphogenesis, GO:0048547|gut morphogenesis, ! hemoglobin metabolic process GO:0020027 7 7 0,000 0,04001182 0,10519512 ! regulation of exit from mitosis GO:0007096 7 7 0,000 0,04001182 0,10504527 ! protein targeting to ER GO:0045047 8 7 0,000 0,04001182 0,10489584 ! cell differentiation in spinal cord GO:0021515 7 7 0,000 0,04001182 0,10474684 ! endoderm development GO:0007492 7 7 0,000 0,04001182 0,10459827 ! regulation of defense response to virus GO:0050688 7 7 0,000 0,04001182 0,10445011 ! glycolipid biosynthetic process GO:0009247 7 7 0,000 0,04001182 0,10430237 GO:0006688|glycosphingolipid biosynthetic process, ! response to hexose stimulus GO:0009746 7 7 0,000 0,04001182 0,10415505 GO:0034284|response to monosaccharide stimulus, GO:0009749|response to glucose stimulus, ! membrane protein ectodomain proteolysis GO:0006509 7 7 0,000 0,04001182 0,10400815 GO:0033619|membrane protein proteolysis, ! positive regulation of survival gene product expression GO:0045885 7 7 0,000 0,04001182 0,10386166 ! regulation of skeletal muscle fiber development GO:0048742 7 7 0,000 0,04001182 0,10371558 ! cardiac muscle tissue development GO:0048738 7 7 0,000 0,04001182 0,10356991 ! nucleotide-sugar metabolic process GO:0009225 7 7 0,000 0,04001182 0,10342465 ! complement activation, alternative pathway GO:0006957 7 7 0,000 0,04001182 0,1032798 ! arachidonic acid secretion GO:0050482 7 7 0,000 0,04001182 0,10313535 GO:0032309|icosanoid secretion, ! polyamine biosynthetic process GO:0006596 7 7 0,000 0,04001182 0,10299131 ! response to X-ray GO:0010165 7 7 0,000 0,04001182 0,10284767 ! regulation of intracellular pH GO:0051453 7 7 0,000 0,04001182 0,10270443 ! UV protection GO:0009650 7 7 0,000 0,04001182 0,10256158 ! DNA integration GO:0015074 7 7 0,000 0,04001182 0,10241914 ! myofibril assembly GO:0030239 7 7 0,000 0,04001182 0,10227708 GO:0055002|striated muscle cell development, ! positive regulation of carbohydrate metabolic process GO:0045913 7 7 0,000 0,04001182 0,10213543 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! positive regulation of muscle contraction GO:0045933 7 7 0,000 0,04001182 0,10199416 ! negative regulation of muscle contraction GO:0045932 7 7 0,000 0,04001182 0,10185328 ! chondroitin sulfate biosynthetic process GO:0030206 7 7 0,000 0,04001182 0,1017128 GO:0030204|chondroitin sulfate metabolic process, ! regulation of exocytosis GO:0017157 8 7 0,000 0,04001182 0,1015727 ! phosphatidylcholine biosynthetic process GO:0006656 7 7 0,000 0,04001182 0,10143298 ! heparan sulfate proteoglycan metabolic process GO:0030201 7 7 0,000 0,04001182 0,10129365 GO:0015012|heparan sulfate proteoglycan biosynthetic process, ! stem cell development GO:0048864 7 7 0,000 0,04001182 0,1011547 GO:0019827|stem cell maintenance, ! alpha-beta T cell differentiation GO:0046632 7 7 0,000 0,04001182 0,10101613 ! negative regulation of myeloid leukocyte differentiation GO:0002762 7 7 0,000 0,04001182 0,10087794 ! NLS-bearing substrate import into nucleus GO:0006607 7 7 0,000 0,04001182 0,10074013 ! axon cargo transport GO:0008088 7 7 0,000 0,04001182 0,1006027 ! eating behavior GO:0042755 7 7 0,000 0,04001182 0,10046564 ! RNA-dependent DNA replication GO:0006278 7 7 0,000 0,04001182 0,10032895 ! purine nucleoside triphosphate catabolic process GO:0009146 7 7 0,000 0,04001182 0,10019263 ! regulation of interleukin-8 production GO:0032677 7 7 0,000 0,04001182 0,10005669 ! purine ribonucleotide catabolic process GO:0009154 7 7 0,000 0,04001182 0,09992111 ! ribosomal small subunit biogenesis GO:0042274 7 7 0,000 0,04001182 0,0997859 ! cranial nerve development GO:0021545 7 7 0,000 0,04001182 0,09965105 ! protein import into peroxisome matrix GO:0016558 7 7 0,000 0,04001182 0,09951657 ! induction of an organ GO:0001759 7 7 0,000 0,04001182 0,09938245 ! leukocyte activation during immune response GO:0002366 7 7 0,000 0,04001182 0,09924869 GO:0002263|cell activation during immune response, ! response to estradiol stimulus GO:0032355 7 7 0,000 0,04001182 0,09911529 ! autonomic nervous system development GO:0048483 7 7 0,000 0,04001182 0,09898225 ! intracellular lipid transport GO:0032365 7 7 0,000 0,04001182 0,09884957 ! detection of chemical stimulus GO:0009593 8 7 0,000 0,04001182 0,09871724 ! platelet activation GO:0030168 8 7 0,000 0,04001182 0,09858526 ! negative regulation of cytokine secretion GO:0050710 7 7 0,000 0,04001182 0,09845364 ! regulation of interleukin-1 secretion GO:0050704 7 7 0,000 0,04001182 0,09832237 ! natural killer cell activation GO:0030101 7 7 0,000 0,04001182 0,09819145 ! response to gamma radiation GO:0010332 8 7 0,000 0,04001182 0,09806087 ! NADP metabolic process GO:0006739 7 7 0,000 0,04001182 0,09793065 ! neuromuscular synaptic transmission GO:0007274 7 7 0,000 0,04001182 0,09780077 ! synaptic transmission, cholinergic GO:0007271 7 7 0,000 0,04001182 0,09767123 ! ubiquinone metabolic process GO:0006743 7 7 0,000 0,04001182 0,09754203 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, GO:0042375|quinone cofactor metabolic process, ! regulation of macrophage differentiation GO:0045649 8 7 0,000 0,04001182 0,09741318 ! positive regulation of acute inflammatory response GO:0002675 7 7 0,000 0,04001182 0,09728467 ! regulation of osteoclast differentiation GO:0045670 7 7 0,000 0,04001182 0,09715649 ! negative regulation of cell-substrate adhesion GO:0010812 8 7 0,000 0,04001182 0,09702865 GO:0001953|negative regulation of cell-matrix adhesion, ! multicellular organismal water homeostasis GO:0050891 7 7 0,000 0,04001182 0,09690115 ! regulation of ATPase activity GO:0043462 7 7 0,000 0,04001182 0,09677399 ! cell-cell recognition GO:0009988 8 7 0,000 0,04001182 0,09664715 ! dopamine metabolic process GO:0042417 7 7 0,000 0,04001182 0,09652065 ! cAMP biosynthetic process GO:0006171 7 7 0,000 0,04001182 0,09639448 ! oxygen transport GO:0015671 7 7 0,000 0,04001182 0,09626864 ! pyridine nucleotide biosynthetic process GO:0019363 7 7 0,000 0,04001182 0,09614313 ! biogenic amine catabolic process GO:0042402 7 7 0,000 0,04001182 0,09601794 ! regulation of axon extension GO:0030516 7 7 0,000 0,04001182 0,09589308 ! cell killing GO:0001906 7 7 0,000 0,04001182 0,09576854 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 7 7 0,000 0,04001182 0,09564433 ! adult feeding behavior GO:0008343 7 7 0,000 0,04001182 0,09552044 ! pyrimidine nucleotide catabolic process GO:0006244 7 7 0,000 0,04001182 0,09539687 ! positive regulation of protein polymerization GO:0032273 7 7 0,000 0,04001182 0,09527361 ! T cell receptor signaling pathway GO:0050852 7 7 0,000 0,04001182 0,09515068 ! response to cold GO:0009409 7 7 0,000 0,04001182 0,09502806 ! in utero embryonic development GO:0001701 55 55 1,000 0,04032773 0,09565509 ! extracellular structure organization GO:0043062 56 56 1,000 0,04167031 0,09871258 ! regulation of nervous system development GO:0051960 57 56 1,000 0,04167031 0,09858586 ! regulation of binding GO:0051098 60 57 1,000 0,04302969 0,10167144 ! regulation of skeletal muscle tissue development GO:0048641 8 8 0,000 0,04559883 0,10760389 ! negative regulation of muscle development GO:0048635 8 8 0,000 0,04559883 0,10746629 ! very-long-chain fatty acid metabolic process GO:0000038 8 8 0,000 0,04559883 0,10732904 ! positive regulation of translation GO:0045727 8 8 0,000 0,04559883 0,10719214 ! positive regulation of cell killing GO:0031343 8 8 0,000 0,04559883 0,10705559 ! superoxide anion generation GO:0042554 8 8 0,000 0,04559883 0,10691939 ! sulfur amino acid biosynthetic process GO:0000097 8 8 0,000 0,04559883 0,10678353 ! cGMP metabolic process GO:0046068 8 8 0,000 0,04559883 0,10664802 GO:0006182|cGMP biosynthetic process, ! thyroid gland development GO:0030878 8 8 0,000 0,04559883 0,10651285 ! 'de novo' protein folding GO:0006458 8 8 0,000 0,04559883 0,10637802 ! dicarboxylic acid transport GO:0006835 8 8 0,000 0,04559883 0,10624354 ! phosphoinositide phosphorylation GO:0046854 8 8 0,000 0,04559883 0,10610939 ! embryonic hindlimb morphogenesis GO:0035116 8 8 0,000 0,04559883 0,10597559 ! zinc ion transport GO:0006829 8 8 0,000 0,04559883 0,10584211 ! embryonic forelimb morphogenesis GO:0035115 8 8 0,000 0,04559883 0,10570898 ! folic acid and derivative biosynthetic process GO:0009396 8 8 0,000 0,04559883 0,10557618 ! regulation of neuronal synaptic plasticity GO:0048168 8 8 0,000 0,04559883 0,10544371 ! cardiac muscle contraction GO:0060048 8 8 0,000 0,04559883 0,10531158 ! lipid localization GO:0010876 8 8 0,000 0,04559883 0,10517977 GO:0019915|lipid storage, ! response to pain GO:0048265 8 8 0,000 0,04559883 0,1050483 ! response to cAMP GO:0051591 8 8 0,000 0,04559883 0,10491715 ! COPI coating of Golgi vesicle GO:0048205 8 8 0,000 0,04559883 0,10478633 GO:0048200|Golgi transport vesicle coating, ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 8 0,000 0,04559883 0,10465584 ! negative regulation of transcription factor import into nucleus GO:0042992 8 8 0,000 0,04559883 0,10452567 ! negative regulation of ion transport GO:0043271 8 8 0,000 0,04559883 0,10439582 ! regulation of response to extracellular stimulus GO:0032104 8 8 0,000 0,04559883 0,1042663 GO:0032107|regulation of response to nutrient levels, ! adult walking behavior GO:0007628 8 8 0,000 0,04559883 0,1041371 ! sensory perception of taste GO:0050909 8 8 0,000 0,04559883 0,10400822 ! organelle fusion GO:0048284 8 8 0,000 0,04559883 0,10387965 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 8 8 0,000 0,04559883 0,10375141 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! T cell selection GO:0045058 8 8 0,000 0,04559883 0,10362348 ! negative regulation of proteolysis GO:0045861 8 8 0,000 0,04559883 0,10349586 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 8 8 0,000 0,04559883 0,10336856 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 8 8 0,000 0,04559883 0,10324157 ! sperm motility GO:0030317 8 8 0,000 0,04559883 0,10311489 ! regulation of striated muscle contraction GO:0006942 8 8 0,000 0,04559883 0,10298853 ! DNA duplex unwinding GO:0032508 8 8 0,000 0,04559883 0,10286247 GO:0032392|DNA geometric change, ! glycine metabolic process GO:0006544 8 8 0,000 0,04559883 0,10273672 ! ribonucleotide catabolic process GO:0009261 8 8 0,000 0,04559883 0,10261128 ! negative regulation of microtubule depolymerization GO:0007026 8 8 0,000 0,04559883 0,10248615 GO:0031114|regulation of microtubule depolymerization, ! phosphagen metabolic process GO:0006599 8 8 0,000 0,04559883 0,10236131 GO:0006600|creatine metabolic process, ! polyamine metabolic process GO:0006595 8 8 0,000 0,04559883 0,10223679 ! Golgi organization GO:0007030 8 8 0,000 0,04559883 0,10211256 ! cell-cell junction assembly GO:0007043 8 8 0,000 0,04559883 0,10198864 ! regulation of stress fiber formation GO:0051492 9 8 0,000 0,04559883 0,10186502 ! mannose metabolic process GO:0006013 9 8 0,000 0,04559883 0,10174169 ! NAD metabolic process GO:0019674 8 8 0,000 0,04559883 0,10161867 ! sex determination GO:0007530 8 8 0,000 0,04559883 0,10149594 ! negative regulation of mitotic cell cycle GO:0045930 9 8 0,000 0,04559883 0,10137351 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 8 8 0,000 0,04559883 0,10125137 ! response to fungus GO:0009620 8 8 0,000 0,04559883 0,10112953 ! stem cell differentiation GO:0048863 8 8 0,000 0,04559883 0,10100798 ! alpha-beta T cell activation GO:0046631 8 8 0,000 0,04559883 0,10088672 ! positive regulation of myeloid leukocyte differentiation GO:0002763 9 8 0,000 0,04559883 0,10076575 ! embryonic digit morphogenesis GO:0042733 8 8 0,000 0,04559883 0,10064508 ! regulation of cytokine production during immune response GO:0002718 8 8 0,000 0,04559883 0,10052469 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 0,04559883 0,10040459 ! regulation of vasodilation GO:0042312 8 8 0,000 0,04559883 0,10028477 ! vasoconstriction GO:0042310 8 8 0,000 0,04559883 0,10016524 ! regulation of T cell mediated immunity GO:0002709 8 8 0,000 0,04559883 0,100046 ! muscle cell development GO:0055001 8 8 0,000 0,04559883 0,09992704 ! nucleoside triphosphate catabolic process GO:0009143 8 8 0,000 0,04559883 0,09980836 ! regulation of fatty acid metabolic process GO:0019217 8 8 0,000 0,04559883 0,09968996 ! sensory perception of pain GO:0019233 8 8 0,000 0,04559883 0,09957185 ! gastrulation with mouth forming second GO:0001702 8 8 0,000 0,04559883 0,09945401 ! immunoglobulin production during immune response GO:0002381 8 8 0,000 0,04559883 0,09933645 GO:0002208|somatic diversification of immunoglobulins during immune response, GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! mRNA cleavage GO:0006379 8 8 0,000 0,04559883 0,09921917 ! chromatin silencing GO:0006342 8 8 0,000 0,04559883 0,09910217 ! tissue regeneration GO:0042246 8 8 0,000 0,04559883 0,09898544 ! salivary gland development GO:0007431 8 8 0,000 0,04559883 0,09886899 ! negative regulation of blood coagulation GO:0030195 9 8 0,000 0,04559883 0,09875281 ! T cell homeostasis GO:0043029 8 8 0,000 0,04559883 0,0986369 ! peptide biosynthetic process GO:0043043 9 8 0,000 0,04559883 0,09852126 ! water homeostasis GO:0030104 8 8 0,000 0,04559883 0,0984059 ! cofactor transport GO:0051181 8 8 0,000 0,04559883 0,09829081 ! regulation of acute inflammatory response GO:0002673 8 8 0,000 0,04559883 0,09817598 ! acid secretion GO:0046717 8 8 0,000 0,04559883 0,09806142 ! C21-steroid hormone biosynthetic process GO:0006700 8 8 0,000 0,04559883 0,09794713 ! protein-chromophore linkage GO:0018298 9 8 0,000 0,04559883 0,09783311 ! regulation of immunoglobulin production GO:0002637 8 8 0,000 0,04559883 0,09771935 ! branched chain family amino acid metabolic process GO:0009081 8 8 0,000 0,04559883 0,09760585 ! catecholamine biosynthetic process GO:0042423 8 8 0,000 0,04559883 0,09749262 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 8 8 0,000 0,04559883 0,09737965 ! regulation of generation of precursor metabolites and energy GO:0043467 8 8 0,000 0,04559883 0,09726694 ! aromatic compound biosynthetic process GO:0019438 8 8 0,000 0,04559883 0,0971545 ! release of cytochrome c from mitochondria GO:0001836 9 8 0,000 0,04559883 0,09704231 ! regulation of organic acid transport GO:0032890 8 8 0,000 0,04559883 0,09693038 ! positive regulation of calcium ion transport GO:0051928 8 8 0,000 0,04559883 0,09681871 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 8 8 0,000 0,04559883 0,09670729 ! regulation of multi-organism process GO:0043900 8 8 0,000 0,04559883 0,09659614 ! positive regulation of amine transport GO:0051954 8 8 0,000 0,04559883 0,09648523 ! developmental induction GO:0031128 8 8 0,000 0,04559883 0,09637459 GO:0045168|cell-cell signaling involved in cell fate specification, ! peptide hormone secretion GO:0030072 8 8 0,000 0,04559883 0,09626419 ! positive regulation of calcium-mediated signaling GO:0050850 8 8 0,000 0,04559883 0,09615405 ! actin filament polymerization GO:0030041 9 8 0,000 0,04559883 0,09604416 ! cytoplasmic sequestering of protein GO:0051220 8 8 0,000 0,04559883 0,09593452 ! peptide hormone processing GO:0016486 8 8 0,000 0,04559883 0,09582513 ! positive regulation of synaptic transmission GO:0050806 8 8 0,000 0,04559883 0,09571599 ! regulation of steroid biosynthetic process GO:0050810 8 8 0,000 0,04559883 0,0956071 ! regulation of cell development GO:0060284 60 59 1,000 0,04579794 0,09591545 ! protein localization in organelle GO:0033365 59 59 1,000 0,04579794 0,09580658 ! regulation of protein amino acid phosphorylation GO:0001932 62 61 1,000 0,04863064 0,10161708 ! morphogenesis of an epithelium GO:0002009 63 62 1,000 0,0500706 0,1045075 GO:0060429|epithelium development, ! axonogenesis GO:0007409 66 62 1,000 0,0500706 0,10438928 ! protein import GO:0017038 62 62 1,000 0,0500706 0,10427132 ! di-, tri-valent inorganic cation transport GO:0015674 63 62 1,000 0,0500706 0,10415363 ! regulation of lymphocyte activation GO:0051249 62 62 1,000 0,0500706 0,10403621 ! lactation GO:0007595 10 9 0,000 0,05115413 0,10616786 ! embryonic pattern specification GO:0009880 10 9 0,000 0,05115413 0,10604844 ! positive regulation of cell size GO:0045793 9 9 0,000 0,05115413 0,10592929 ! positive regulation of cell projection organization GO:0031346 9 9 0,000 0,05115413 0,1058104 ! regulation of membrane protein ectodomain proteolysis GO:0051043 9 9 0,000 0,05115413 0,10569178 ! positive regulation of protein complex assembly GO:0031334 9 9 0,000 0,05115413 0,10557342 ! cortical actin cytoskeleton organization GO:0030866 10 9 0,000 0,05115413 0,10545533 ! negative regulation of cell cycle process GO:0010948 9 9 0,000 0,05115413 0,1053375 ! phospholipid catabolic process GO:0009395 9 9 0,000 0,05115413 0,10521994 ! copper ion transport GO:0006825 9 9 0,000 0,05115413 0,10510264 ! lipid phosphorylation GO:0046834 9 9 0,000 0,05115413 0,10498559 ! aminoglycan catabolic process GO:0006026 9 9 0,000 0,05115413 0,10486881 ! Golgi vesicle budding GO:0048194 9 9 0,000 0,05115413 0,10475229 ! regulation of cell-cell adhesion GO:0022407 9 9 0,000 0,05115413 0,10463603 ! RNA polyadenylation GO:0043631 9 9 0,000 0,05115413 0,10452003 GO:0006378|mRNA polyadenylation, ! gamma-aminobutyric acid signaling pathway GO:0007214 9 9 0,000 0,05115413 0,10440428 ! regulation of postsynaptic membrane potential GO:0060078 9 9 0,000 0,05115413 0,10428879 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 9 9 0,000 0,05115413 0,10417355 ! negative regulation of cytokine biosynthetic process GO:0042036 9 9 0,000 0,05115413 0,10405857 ! phospholipid efflux GO:0033700 9 9 0,000 0,05115413 0,10394384 ! response to alkaloid GO:0043279 10 9 0,000 0,05115413 0,10382937 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 9 9 0,000 0,05115413 0,10371514 ! cytokine biosynthetic process GO:0042089 9 9 0,000 0,05115413 0,10360117 GO:0042107|cytokine metabolic process, ! negative regulation of gene expression, epigenetic GO:0045814 9 9 0,000 0,05115413 0,10348745 ! regulation of interleukin-2 biosynthetic process GO:0045076 9 9 0,000 0,05115413 0,10337397 ! response to ethanol GO:0045471 9 9 0,000 0,05115413 0,10326075 ! pyrimidine ribonucleotide metabolic process GO:0009218 9 9 0,000 0,05115413 0,10314777 ! methionine metabolic process GO:0006555 9 9 0,000 0,05115413 0,10303504 ! glutamine metabolic process GO:0006541 9 9 0,000 0,05115413 0,10292256 ! cerebral cortex development GO:0021987 9 9 0,000 0,05115413 0,10281032 ! response to osmotic stress GO:0006970 9 9 0,000 0,05115413 0,10269833 ! pigmentation during development GO:0048066 9 9 0,000 0,05115413 0,10258658 ! reverse cholesterol transport GO:0043691 9 9 0,000 0,05115413 0,10247507 ! central nervous system neuron development GO:0021954 10 9 0,000 0,05115413 0,1023638 ! pyrimidine ribonucleoside metabolic process GO:0046131 9 9 0,000 0,05115413 0,10225278 ! nucleobase biosynthetic process GO:0046112 9 9 0,000 0,05115413 0,102142 ! substrate-bound cell migration GO:0006929 9 9 0,000 0,05115413 0,10203145 ! neurotransmitter metabolic process GO:0042133 11 9 0,000 0,05115413 0,10192115 ! negative regulation of caspase activity GO:0043154 9 9 0,000 0,05115413 0,10181108 ! L-glutamate transport GO:0015813 9 9 0,000 0,05115413 0,10170126 GO:0015800|acidic amino acid transport, ! peptide secretion GO:0002790 9 9 0,000 0,05115413 0,10159166 ! regulation of dephosphorylation GO:0035303 9 9 0,000 0,05115413 0,10148231 ! cotranslational protein targeting to membrane GO:0006613 10 9 0,000 0,05115413 0,10137319 ! positive regulation of alpha-beta T cell differentiation GO:0046638 9 9 0,000 0,05115413 0,1012643 ! ventricular cardiac muscle morphogenesis GO:0055010 9 9 0,000 0,05115413 0,10115565 ! behavioral interaction between organisms GO:0051705 9 9 0,000 0,05115413 0,10104723 ! negative regulation of protein import into nucleus GO:0042308 9 9 0,000 0,05115413 0,10093904 ! DNA replication initiation GO:0006270 9 9 0,000 0,05115413 0,10083108 ! prostaglandin metabolic process GO:0006693 9 9 0,000 0,05115413 0,10072336 GO:0006692|prostanoid metabolic process, ! T cell differentiation in the thymus GO:0033077 9 9 0,000 0,05115413 0,10061586 ! regulation of cellular pH GO:0030641 9 9 0,000 0,05115413 0,1005086 ! DNA fragmentation involved in apoptosis GO:0006309 9 9 0,000 0,05115413 0,10040156 ! regulation of immunoglobulin mediated immune response GO:0002889 9 9 0,000 0,05115413 0,10029475 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 10 9 0,000 0,05115413 0,10018817 ! positive regulation of oxidoreductase activity GO:0051353 9 9 0,000 0,05115413 0,10008181 ! positive regulation of cytokine secretion GO:0050715 9 9 0,000 0,05115413 0,09997568 ! negative regulation of inflammatory response GO:0050728 9 9 0,000 0,05115413 0,09986977 ! negative regulation of protein secretion GO:0050709 9 9 0,000 0,05115413 0,09976409 ! positive regulation of transmission of nerve impulse GO:0051971 9 9 0,000 0,05115413 0,09965863 ! collagen catabolic process GO:0030574 9 9 0,000 0,05115413 0,09955339 ! aromatic amino acid family catabolic process GO:0009074 9 9 0,000 0,05115413 0,09944838 ! purine base metabolic process GO:0006144 9 9 0,000 0,05115413 0,09934359 ! gas transport GO:0015669 9 9 0,000 0,05115413 0,09923901 ! cholesterol efflux GO:0033344 9 9 0,000 0,05115413 0,09913466 ! regulation of leukocyte mediated cytotoxicity GO:0001910 9 9 0,000 0,05115413 0,09903053 ! estrogen receptor signaling pathway GO:0030520 9 9 0,000 0,05115413 0,09892661 ! somatic recombination of immunoglobulin gene segments GO:0016447 9 9 0,000 0,05115413 0,09882292 ! regulation of actin filament bundle formation GO:0032231 10 9 0,000 0,05115413 0,09871944 ! defense response to virus GO:0051607 9 9 0,000 0,05115413 0,09861618 ! regulation of calcium-mediated signaling GO:0050848 9 9 0,000 0,05115413 0,09851313 ! actin filament-based movement GO:0030048 9 9 0,000 0,05115413 0,0984103 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 9 9 0,000 0,05115413 0,09830768 ! negative regulation of cellular component organization GO:0051129 65 63 1,000 0,05152602 0,09891922 ! glucose metabolic process GO:0006006 63 63 1,000 0,05152602 0,09881628 ! regulation of response to external stimulus GO:0032101 65 64 1,000 0,05299666 0,10153102 ! positive regulation of protein metabolic process GO:0051247 64 64 1,000 0,05299666 0,10142559 ! regulation of hormone levels GO:0010817 66 65 1,000 0,05448232 0,1041607 ! polysaccharide metabolic process GO:0005976 69 66 1,000 0,05598278 0,10691841 ! protein import into nucleus, docking GO:0000059 10 10 0,000 0,0566779 0,10813393 ! regulation of protein ubiquitination GO:0031396 10 10 0,000 0,0566779 0,1080221 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 10 10 0,000 0,0566779 0,10791051 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 10 10 0,000 0,0566779 0,10779915 ! regulation of glucose metabolic process GO:0010906 10 10 0,000 0,0566779 0,10768802 ! ER-associated protein catabolic process GO:0030433 10 10 0,000 0,0566779 0,10757711 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of cell killing GO:0031341 10 10 0,000 0,0566779 0,10746643 ! neuron maturation GO:0042551 10 10 0,000 0,0566779 0,10735599 ! pteridine and derivative metabolic process GO:0042558 10 10 0,000 0,0566779 0,10724576 ! positive regulation of anti-apoptosis GO:0045768 10 10 0,000 0,0566779 0,10713577 GO:0045767|regulation of anti-apoptosis, ! cortical cytoskeleton organization GO:0030865 11 10 0,000 0,0566779 0,107026 ! regulation of lipid biosynthetic process GO:0046890 10 10 0,000 0,0566779 0,10691645 ! reciprocal meiotic recombination GO:0007131 10 10 0,000 0,0566779 0,10680713 ! hormone secretion GO:0046879 10 10 0,000 0,0566779 0,10669803 ! glucosamine metabolic process GO:0006041 10 10 0,000 0,0566779 0,10658916 GO:0006044|N-acetylglucosamine metabolic process, ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 10 10 0,000 0,0566779 0,1064805 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! inositol metabolic process GO:0006020 10 10 0,000 0,0566779 0,10637207 ! cAMP metabolic process GO:0046058 10 10 0,000 0,0566779 0,10626386 ! vesicle targeting, to, from or within Golgi GO:0048199 10 10 0,000 0,0566779 0,10615587 ! forelimb morphogenesis GO:0035136 10 10 0,000 0,0566779 0,1060481 ! glial cell development GO:0021782 10 10 0,000 0,0566779 0,10594054 ! phototransduction GO:0007602 11 10 0,000 0,0566779 0,10583321 ! calcium-independent cell-cell adhesion GO:0016338 10 10 0,000 0,0566779 0,10572609 ! auditory receptor cell differentiation GO:0042491 10 10 0,000 0,0566779 0,10561919 ! apoptotic mitochondrial changes GO:0008637 11 10 0,000 0,0566779 0,1055125 ! fat cell differentiation GO:0045444 10 10 0,000 0,0566779 0,10540603 ! myoblast differentiation GO:0045445 10 10 0,000 0,0566779 0,10529977 ! centrosome cycle GO:0007098 10 10 0,000 0,0566779 0,10519373 ! inactivation of MAPK activity GO:0000188 10 10 0,000 0,0566779 0,1050879 ! positive regulation of proteolysis GO:0045862 10 10 0,000 0,0566779 0,10498229 ! response to carbohydrate stimulus GO:0009743 10 10 0,000 0,0566779 0,10487688 ! regulation of survival gene product expression GO:0045884 10 10 0,000 0,0566779 0,10477169 ! induction of apoptosis via death domain receptors GO:0008625 10 10 0,000 0,0566779 0,10466671 ! epidermis morphogenesis GO:0048730 10 10 0,000 0,0566779 0,10456194 ! protein polyubiquitination GO:0000209 10 10 0,000 0,0566779 0,10445737 ! glutamate metabolic process GO:0006536 11 10 0,000 0,0566779 0,10435302 ! plasma membrane organization GO:0007009 10 10 0,000 0,0566779 0,10424888 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 10 10 0,000 0,0566779 0,10414494 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! lysosomal transport GO:0007041 10 10 0,000 0,0566779 0,10404121 ! cellular response to unfolded protein GO:0034620 10 10 0,000 0,0566779 0,10393769 GO:0030968|endoplasmic reticulum unfolded protein response, ! central nervous system neuron differentiation GO:0021953 11 10 0,000 0,0566779 0,10383437 ! purine ribonucleoside metabolic process GO:0046128 10 10 0,000 0,0566779 0,10373126 GO:0042278|purine nucleoside metabolic process, ! vesicle coating GO:0006901 10 10 0,000 0,0566779 0,10362835 ! exocrine system development GO:0035272 10 10 0,000 0,0566779 0,10352564 ! cell structure disassembly during apoptosis GO:0006921 10 10 0,000 0,0566779 0,10342314 ! embryo implantation GO:0007566 11 10 0,000 0,0566779 0,10332085 ! regulation of protein binding GO:0043393 11 10 0,000 0,0566779 0,10321875 ! protein targeting to peroxisome GO:0006625 10 10 0,000 0,0566779 0,10311686 ! protein targeting to mitochondrion GO:0006626 10 10 0,000 0,0566779 0,10301516 GO:0070585|protein localization in mitochondrion, ! regulation of alpha-beta T cell differentiation GO:0046637 10 10 0,000 0,0566779 0,10291367 ! intermediate filament cytoskeleton organization GO:0045104 10 10 0,000 0,0566779 0,10281238 ! protein export from nucleus GO:0006611 10 10 0,000 0,0566779 0,10271128 ! negative regulation of immune response GO:0050777 10 10 0,000 0,0566779 0,10261039 ! cytolysis GO:0019835 10 10 0,000 0,0566779 0,10250969 ! mismatch repair GO:0006298 10 10 0,000 0,0566779 0,10240919 ! regulation of B cell differentiation GO:0045577 10 10 0,000 0,0566779 0,10230889 ! histone deacetylation GO:0016575 10 10 0,000 0,0566779 0,10220878 ! mRNA splice site selection GO:0006376 11 10 0,000 0,0566779 0,10210887 ! synaptic vesicle transport GO:0048489 11 10 0,000 0,0566779 0,10200916 ! gland morphogenesis GO:0022612 10 10 0,000 0,0566779 0,10190963 ! positive regulation of neurological system process GO:0031646 10 10 0,000 0,0566779 0,10181031 ! sphingolipid biosynthetic process GO:0030148 10 10 0,000 0,0566779 0,10171117 GO:0046467|membrane lipid biosynthetic process, ! sphingolipid catabolic process GO:0030149 10 10 0,000 0,0566779 0,10161223 GO:0046466|membrane lipid catabolic process, ! nerve-nerve synaptic transmission GO:0007270 10 10 0,000 0,0566779 0,10151348 ! regulation of epidermis development GO:0045682 10 10 0,000 0,0566779 0,10141493 ! folic acid and derivative metabolic process GO:0006760 10 10 0,000 0,0566779 0,10131656 ! negative regulation of neuron differentiation GO:0045665 10 10 0,000 0,0566779 0,10121839 ! aspartate family amino acid biosynthetic process GO:0009067 10 10 0,000 0,0566779 0,1011204 ! lymphocyte homeostasis GO:0002260 10 10 0,000 0,0566779 0,10102261 ! nerve development GO:0021675 10 10 0,000 0,0566779 0,100925 ! gut development GO:0048565 10 10 0,000 0,0566779 0,10082758 ! embryonic organ morphogenesis GO:0048562 10 10 0,000 0,0566779 0,10073035 ! positive regulation of neuron apoptosis GO:0043525 10 10 0,000 0,0566779 0,10063331 ! mRNA 3'-end processing GO:0031124 10 10 0,000 0,0566779 0,10053645 ! antigen receptor-mediated signaling pathway GO:0050851 10 10 0,000 0,0566779 0,10043978 ! negative regulation of coagulation GO:0050819 11 10 0,000 0,0566779 0,1003433 ! protein stabilization GO:0050821 10 10 0,000 0,0566779 0,100247 ! cell morphogenesis involved in neuron differentiation GO:0048667 72 67 1,000 0,05749783 0,1015997 GO:0048812|neuron projection morphogenesis, GO:0048858|cell projection morphogenesis, ! regulation of leukocyte activation GO:0002694 69 69 1,000 0,06057084 0,10692726 ! cell part morphogenesis GO:0032990 75 70 1,000 0,06212839 0,10957189 ! wound healing GO:0042060 74 70 1,000 0,06212839 0,10946714 ! carboxylic acid biosynthetic process GO:0046394 70 70 1,000 0,06212839 0,10936259 GO:0016053|organic acid biosynthetic process, ! protein secretion GO:0009306 11 11 0,000 0,06217032 0,10933196 ! oligosaccharide metabolic process GO:0009311 11 11 0,000 0,06217032 0,10922773 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 11 11 0,000 0,06217032 0,10912371 ! myeloid leukocyte differentiation GO:0002573 12 11 0,000 0,06217032 0,10901988 ! negative regulation of defense response GO:0031348 11 11 0,000 0,06217032 0,10891625 ! G1 phase of mitotic cell cycle GO:0000080 12 11 0,000 0,06217032 0,10881281 ! determination of bilateral symmetry GO:0009855 11 11 0,000 0,06217032 0,10870958 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! positive regulation of hormone secretion GO:0046887 11 11 0,000 0,06217032 0,10860653 ! phosphatidylinositol metabolic process GO:0046488 11 11 0,000 0,06217032 0,10850369 ! skin development GO:0043588 11 11 0,000 0,06217032 0,10840103 ! cellular component assembly involved in morphogenesis GO:0010927 11 11 0,000 0,06217032 0,10829858 ! signal complex assembly GO:0007172 11 11 0,000 0,06217032 0,10819631 ! microtubule-based transport GO:0010970 11 11 0,000 0,06217032 0,10809424 ! endothelial cell migration GO:0043542 11 11 0,000 0,06217032 0,10799236 ! peroxisomal transport GO:0043574 11 11 0,000 0,06217032 0,10789067 ! protein amino acid methylation GO:0006479 11 11 0,000 0,06217032 0,10778918 GO:0008213|protein amino acid alkylation, ! heart contraction GO:0060047 11 11 0,000 0,06217032 0,10768787 GO:0003015|heart process, ! detection of light stimulus involved in sensory perception GO:0050962 12 11 0,000 0,06217032 0,10758675 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 11 11 0,000 0,06217032 0,10748583 ! T cell proliferation GO:0042098 11 11 0,000 0,06217032 0,10738509 ! regulation of transmembrane transporter activity GO:0022898 11 11 0,000 0,06217032 0,10728454 GO:0032412|regulation of ion transmembrane transporter activity, GO:0032409|regulation of transporter activity, ! negative regulation of endothelial cell proliferation GO:0001937 11 11 0,000 0,06217032 0,10718418 ! regulation of viral genome replication GO:0045069 11 11 0,000 0,06217032 0,10708401 ! spinal cord development GO:0021510 11 11 0,000 0,06217032 0,10698403 ! activation of MAPKK activity GO:0000186 12 11 0,000 0,06217032 0,10688423 ! smooth muscle contraction GO:0006939 11 11 0,000 0,06217032 0,10678462 ! cellular response to starvation GO:0009267 11 11 0,000 0,06217032 0,10668519 ! cellular macromolecular complex disassembly GO:0034623 12 11 0,000 0,06217032 0,10658595 ! digestive system process GO:0022600 11 11 0,000 0,06217032 0,10648689 ! mitotic spindle organization GO:0007052 11 11 0,000 0,06217032 0,10638802 ! fucose metabolic process GO:0006004 11 11 0,000 0,06217032 0,10628933 ! membrane budding GO:0006900 11 11 0,000 0,06217032 0,10619082 ! apoptotic nuclear changes GO:0030262 11 11 0,000 0,06217032 0,10609249 ! monoamine transport GO:0015844 11 11 0,000 0,06217032 0,10599435 ! regulation of cellular ketone metabolic process GO:0010565 11 11 0,000 0,06217032 0,10589639 ! response to lipopolysaccharide GO:0032496 11 11 0,000 0,06217032 0,10579861 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 11 11 0,000 0,06217032 0,10570101 ! body fluid secretion GO:0007589 11 11 0,000 0,06217032 0,10560359 ! G1/S transition checkpoint GO:0031575 12 11 0,000 0,06217032 0,10550635 ! positive regulation of alpha-beta T cell activation GO:0046635 11 11 0,000 0,06217032 0,10540929 ! intermediate filament-based process GO:0045103 11 11 0,000 0,06217032 0,1053124 ! cardiac muscle tissue morphogenesis GO:0055008 11 11 0,000 0,06217032 0,1052157 GO:0060415|muscle tissue morphogenesis, ! interaction with host GO:0051701 11 11 0,000 0,06217032 0,10511917 ! membrane depolarization GO:0051899 11 11 0,000 0,06217032 0,10502282 ! regulation of interleukin-2 production GO:0032663 11 11 0,000 0,06217032 0,10492664 ! regulation of ARF GTPase activity GO:0032312 11 11 0,000 0,06217032 0,10483064 ! oogenesis GO:0048477 11 11 0,000 0,06217032 0,10473482 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 11 11 0,000 0,06217032 0,10463917 ! regulation of cellular carbohydrate metabolic process GO:0010675 11 11 0,000 0,06217032 0,1045437 GO:0006109|regulation of carbohydrate metabolic process, ! vitamin transport GO:0051180 11 11 0,000 0,06217032 0,1044484 ! muscle maintenance GO:0046716 12 11 0,000 0,06217032 0,10435327 ! vitamin A metabolic process GO:0006776 11 11 0,000 0,06217032 0,10425832 ! hindbrain development GO:0030902 11 11 0,000 0,06217032 0,10416354 ! endocrine process GO:0050886 11 11 0,000 0,06217032 0,10406893 GO:0001990|regulation of systemic arterial blood pressure by hormone, ! aromatic amino acid family metabolic process GO:0009072 11 11 0,000 0,06217032 0,1039745 ! somatic diversification of immunoglobulins GO:0016445 11 11 0,000 0,06217032 0,10388023 ! RNA 3'-end processing GO:0031123 11 11 0,000 0,06217032 0,10378614 ! negative regulation of signal transduction GO:0009968 71 71 1,000 0,0636997 0,10624303 ! regulation of cell activation GO:0050865 71 71 1,000 0,0636997 0,10614697 ! positive regulation of hydrolase activity GO:0051345 72 72 1,000 0,06528456 0,10868966 ! translational initiation GO:0006413 12 12 0,000 0,06763155 0,11249543 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 12 12 0,000 0,06763155 0,11239399 ! positive regulation of angiogenesis GO:0045766 12 12 0,000 0,06763155 0,11229274 ! initiation of viral infection GO:0019059 12 12 0,000 0,06763155 0,11219167 ! DNA catabolic process, endonucleolytic GO:0000737 12 12 0,000 0,06763155 0,11209077 ! iron ion transport GO:0006826 13 12 0,000 0,06763155 0,11199006 ! phosphatidylcholine metabolic process GO:0046470 12 12 0,000 0,06763155 0,11188953 ! amino sugar metabolic process GO:0006040 12 12 0,000 0,06763155 0,11178918 ! post-Golgi vesicle-mediated transport GO:0006892 12 12 0,000 0,06763155 0,11168901 ! protein amino acid ADP-ribosylation GO:0006471 12 12 0,000 0,06763155 0,11158902 ! heterophilic cell adhesion GO:0007157 12 12 0,000 0,06763155 0,11148921 ! collagen metabolic process GO:0032963 12 12 0,000 0,06763155 0,11138958 ! hindlimb morphogenesis GO:0035137 12 12 0,000 0,06763155 0,11129013 ! xenobiotic metabolic process GO:0006805 12 12 0,000 0,06763155 0,11119085 ! glutamate signaling pathway GO:0007215 12 12 0,000 0,06763155 0,11109175 ! C21-steroid hormone metabolic process GO:0008207 13 12 0,000 0,06763155 0,11099282 ! regulation of muscle cell differentiation GO:0051147 13 12 0,000 0,06763155 0,11089407 ! negative regulation of peptidase activity GO:0010466 12 12 0,000 0,06763155 0,1107955 ! actomyosin structure organization GO:0031032 12 12 0,000 0,06763155 0,1106971 ! microtubule organizing center organization GO:0031023 12 12 0,000 0,06763155 0,11059888 GO:0051297|centrosome organization, ! positive regulation of endocytosis GO:0045807 12 12 0,000 0,06763155 0,11050083 ! retinoid metabolic process GO:0001523 12 12 0,000 0,06763155 0,11040296 GO:0016101|diterpenoid metabolic process, ! mitotic chromosome condensation GO:0007076 12 12 0,000 0,06763155 0,11030526 ! positive regulation of innate immune response GO:0045089 12 12 0,000 0,06763155 0,11020773 ! GPI anchor biosynthetic process GO:0006506 12 12 0,000 0,06763155 0,11011037 GO:0006505|GPI anchor metabolic process, ! glycoprotein catabolic process GO:0006516 13 12 0,000 0,06763155 0,11001319 ! acute-phase response GO:0006953 12 12 0,000 0,06763155 0,10991617 ! deoxyribonucleotide catabolic process GO:0009264 12 12 0,000 0,06763155 0,10981933 ! vacuolar transport GO:0007034 12 12 0,000 0,06763155 0,10972266 ! polysaccharide catabolic process GO:0000272 12 12 0,000 0,06763155 0,10962616 ! vesicle docking during exocytosis GO:0006904 12 12 0,000 0,06763155 0,10952982 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 12 12 0,000 0,06763155 0,10943366 ! barbed-end actin filament capping GO:0051016 12 12 0,000 0,06763155 0,10933767 GO:0051693|actin filament capping, ! osteoblast differentiation GO:0001649 12 12 0,000 0,06763155 0,10924184 ! male gonad development GO:0008584 12 12 0,000 0,06763155 0,10914618 ! regulation of insulin secretion GO:0050796 12 12 0,000 0,06763155 0,10905069 ! regulation of alpha-beta T cell activation GO:0046634 12 12 0,000 0,06763155 0,10895537 ! renal system process GO:0003014 12 12 0,000 0,06763155 0,10886021 ! regulation of tumor necrosis factor production GO:0032680 12 12 0,000 0,06763155 0,10876522 ! regulation of steroid metabolic process GO:0019218 12 12 0,000 0,06763155 0,10867039 ! fibroblast growth factor receptor signaling pathway GO:0008543 12 12 0,000 0,06763155 0,10857573 ! regulation of interleukin-6 production GO:0032675 12 12 0,000 0,06763155 0,10848124 ! pallium development GO:0021543 13 12 0,000 0,06763155 0,1083869 ! cell fate determination GO:0001709 12 12 0,000 0,06763155 0,10829274 ! regulation of chromosome organization GO:0033044 12 12 0,000 0,06763155 0,10819873 ! positive regulation of multicellular organism growth GO:0040018 12 12 0,000 0,06763155 0,10810489 ! G1 phase GO:0051318 13 12 0,000 0,06763155 0,10801121 ! regulation of response to biotic stimulus GO:0002831 12 12 0,000 0,06763155 0,1079177 ! positive regulation of adaptive immune response GO:0002821 12 12 0,000 0,06763155 0,10782434 ! detection of light stimulus GO:0009583 13 12 0,000 0,06763155 0,10773115 ! synaptogenesis GO:0007416 12 12 0,000 0,06763155 0,10763812 ! fat-soluble vitamin metabolic process GO:0006775 12 12 0,000 0,06763155 0,10754525 ! hormone transport GO:0009914 12 12 0,000 0,06763155 0,10745253 ! neurotransmitter secretion GO:0007269 14 12 0,000 0,06763155 0,10735998 ! heme biosynthetic process GO:0006783 12 12 0,000 0,06763155 0,10726759 ! spermatid differentiation GO:0048515 13 12 0,000 0,06763155 0,10717536 GO:0007286|spermatid development, ! aromatic compound catabolic process GO:0019439 13 12 0,000 0,06763155 0,10708328 ! pyrimidine nucleotide biosynthetic process GO:0006221 12 12 0,000 0,06763155 0,10699136 ! neural tube closure GO:0001843 13 12 0,000 0,06763155 0,10689961 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! regulation of mitotic metaphase/anaphase transition GO:0030071 13 12 0,000 0,06763155 0,106808 ! negative regulation of translation GO:0017148 12 12 0,000 0,06763155 0,10671656 ! regulation of microtubule polymerization or depolymerization GO:0031110 12 12 0,000 0,06763155 0,10662527 ! cellular monovalent inorganic cation homeostasis GO:0030004 12 12 0,000 0,06763155 0,10653414 ! negative regulation of cell communication GO:0010648 76 76 1,000 0,07175553 0,11293378 ! positive regulation of multicellular organismal process GO:0051240 76 76 1,000 0,07175553 0,11283742 ! positive regulation of DNA replication GO:0045740 14 13 0,000 0,07306176 0,11479355 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 13 13 0,000 0,07306176 0,11469577 GO:0016444|somatic cell DNA recombination, ! negative regulation of actin filament polymerization GO:0030837 13 13 0,000 0,07306176 0,11459816 ! phenol metabolic process GO:0018958 13 13 0,000 0,07306176 0,11450071 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, GO:0009712|catechol metabolic process, ! G2/M transition of mitotic cell cycle GO:0000086 13 13 0,000 0,07306176 0,11440343 ! negative regulation of hormone secretion GO:0046888 13 13 0,000 0,07306176 0,11430631 ! 2'-deoxyribonucleotide metabolic process GO:0009394 13 13 0,000 0,07306176 0,11420936 GO:0019692|deoxyribose phosphate metabolic process, ! intra-Golgi vesicle-mediated transport GO:0006891 13 13 0,000 0,07306176 0,11411257 ! glycosaminoglycan biosynthetic process GO:0006024 13 13 0,000 0,07306176 0,11401595 ! positive regulation of JAK-STAT cascade GO:0046427 13 13 0,000 0,07306176 0,11391949 ! regeneration GO:0031099 13 13 0,000 0,07306176 0,11382319 ! keratinization GO:0031424 13 13 0,000 0,07306176 0,11372705 ! post-embryonic development GO:0009791 14 13 0,000 0,07306176 0,11363108 ! negative regulation of protein modification process GO:0031400 13 13 0,000 0,07306176 0,11353527 ! patterning of blood vessels GO:0001569 13 13 0,000 0,07306176 0,11343962 ! regulation of DNA recombination GO:0000018 13 13 0,000 0,07306176 0,11334413 ! regulation of innate immune response GO:0045088 13 13 0,000 0,07306176 0,11324881 ! mitochondrial membrane organization GO:0007006 13 13 0,000 0,07306176 0,11315364 ! negative regulation of DNA replication GO:0008156 13 13 0,000 0,07306176 0,11305863 ! multicellular organismal macromolecule metabolic process GO:0044259 13 13 0,000 0,07306176 0,11296379 ! response to corticosteroid stimulus GO:0031960 13 13 0,000 0,07306176 0,1128691 GO:0051384|response to glucocorticoid stimulus, ! multicellular organismal catabolic process GO:0044243 13 13 0,000 0,07306176 0,11277457 ! autophagy GO:0006914 13 13 0,000 0,07306176 0,11268019 ! receptor metabolic process GO:0043112 14 13 0,000 0,07306176 0,11258598 ! negative regulation of protein catabolic process GO:0042177 13 13 0,000 0,07306176 0,11249192 ! cell aging GO:0007569 13 13 0,000 0,07306176 0,11239802 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 13 13 0,000 0,07306176 0,11230428 ! coenzyme catabolic process GO:0009109 13 13 0,000 0,07306176 0,11221069 GO:0046356|acetyl-CoA catabolic process, GO:0006099|tricarboxylic acid cycle, ! negative regulation of protein kinase cascade GO:0010741 13 13 0,000 0,07306176 0,11211726 ! purine nucleoside monophosphate metabolic process GO:0009126 13 13 0,000 0,07306176 0,11202399 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of peptide secretion GO:0002791 13 13 0,000 0,07306176 0,11193087 ! regulation of viral reproduction GO:0050792 13 13 0,000 0,07306176 0,1118379 ! nucleobase metabolic process GO:0009112 13 13 0,000 0,07306176 0,11174509 ! regulation of axonogenesis GO:0050770 14 13 0,000 0,07306176 0,11165243 ! positive regulation of neurogenesis GO:0050769 13 13 0,000 0,07306176 0,11155993 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 14 13 0,000 0,07306176 0,11146758 ! nucleotide-excision repair, DNA gap filling GO:0006297 13 13 0,000 0,07306176 0,11137538 ! vasodilation GO:0042311 14 13 0,000 0,07306176 0,11128333 ! positive regulation of leukocyte mediated immunity GO:0002705 13 13 0,000 0,07306176 0,11119144 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 13 13 0,000 0,07306176 0,1110997 ! glycosphingolipid metabolic process GO:0006687 13 13 0,000 0,07306176 0,11100811 GO:0006664|glycolipid metabolic process, ! neural crest cell migration GO:0001755 14 13 0,000 0,07306176 0,11091667 ! neutrophil chemotaxis GO:0030593 14 13 0,000 0,07306176 0,11082538 ! long-chain fatty acid transport GO:0015909 13 13 0,000 0,07306176 0,11073424 ! immunoglobulin production GO:0002377 13 13 0,000 0,07306176 0,11064325 GO:0002440|production of molecular mediator of immune response, ! negative regulation of Wnt receptor signaling pathway GO:0030178 13 13 0,000 0,07306176 0,11055241 ! cell-cell junction organization GO:0045216 13 13 0,000 0,07306176 0,11046172 ! regulation of cell-substrate adhesion GO:0010810 14 13 0,000 0,07306176 0,11037117 GO:0001952|regulation of cell-matrix adhesion, ! response to cytokine stimulus GO:0034097 13 13 0,000 0,07306176 0,11028078 ! activation of JUN kinase activity GO:0007257 13 13 0,000 0,07306176 0,11019053 ! terpenoid metabolic process GO:0006721 13 13 0,000 0,07306176 0,11010044 ! alkene biosynthetic process GO:0043450 13 13 0,000 0,07306176 0,11001048 GO:0019370|leukotriene biosynthetic process, ! purine nucleotide catabolic process GO:0006195 13 13 0,000 0,07306176 0,10992068 ! porphyrin biosynthetic process GO:0006779 13 13 0,000 0,07306176 0,10983102 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of cytokine production GO:0001818 13 13 0,000 0,07306176 0,10974151 ! camera-type eye morphogenesis GO:0048593 13 13 0,000 0,07306176 0,10965214 ! pyrimidine nucleoside metabolic process GO:0006213 13 13 0,000 0,07306176 0,10956292 ! blastocyst development GO:0001824 13 13 0,000 0,07306176 0,10947385 ! telomere organization GO:0032200 13 13 0,000 0,07306176 0,10938492 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 13 13 0,000 0,07306176 0,10929613 ! regulation of amine transport GO:0051952 13 13 0,000 0,07306176 0,10920749 ! inner ear receptor cell differentiation GO:0060113 13 13 0,000 0,07306176 0,10911899 ! protein tetramerization GO:0051262 13 13 0,000 0,07306176 0,10903063 ! regulation of protein modification process GO:0031399 79 78 1,000 0,07506718 0,1119327 ! positive regulation of protein kinase cascade GO:0010740 79 78 1,000 0,07506718 0,11184221 ! nuclear transport GO:0051169 79 79 1,000 0,07674137 0,11424422 GO:0006913|nucleocytoplasmic transport, ! neuron projection development GO:0031175 85 80 1,000 0,07842754 0,11666018 ! neuron fate commitment GO:0048663 14 14 0,000 0,07846114 0,11661604 ! sulfur amino acid metabolic process GO:0000096 14 14 0,000 0,07846114 0,11652207 ! regulation of interferon-gamma production GO:0032649 14 14 0,000 0,07846114 0,11642825 ! cellular aldehyde metabolic process GO:0006081 14 14 0,000 0,07846114 0,11633458 ! acetyl-CoA metabolic process GO:0006084 14 14 0,000 0,07846114 0,11624107 ! cellular iron ion homeostasis GO:0006879 14 14 0,000 0,07846114 0,1161477 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 14 14 0,000 0,07846114 0,11605448 ! protein amino acid deacetylation GO:0006476 14 14 0,000 0,07846114 0,11596142 ! aminoglycan biosynthetic process GO:0006023 14 14 0,000 0,07846114 0,1158685 ! vesicle docking GO:0048278 14 14 0,000 0,07846114 0,11577573 ! superoxide metabolic process GO:0006801 15 14 0,000 0,07846114 0,11568311 ! macromolecular complex disassembly GO:0032984 15 14 0,000 0,07846114 0,11559064 ! calcium-dependent cell-cell adhesion GO:0016339 14 14 0,000 0,07846114 0,11549831 ! mechanoreceptor differentiation GO:0042490 14 14 0,000 0,07846114 0,11540613 ! isoprenoid biosynthetic process GO:0008299 14 14 0,000 0,07846114 0,1153141 ! hair cycle GO:0042633 14 14 0,000 0,07846114 0,11522222 GO:0022404|molting cycle process, GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042303|molting cycle, ! negative regulation of epithelial cell proliferation GO:0050680 14 14 0,000 0,07846114 0,11513048 ! immune response-activating cell surface receptor signaling pathway GO:0002429 14 14 0,000 0,07846114 0,11503889 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! multicellular organismal response to stress GO:0033555 14 14 0,000 0,07846114 0,11494745 ! lysosome organization GO:0007040 14 14 0,000 0,07846114 0,11485614 ! actin polymerization or depolymerization GO:0008154 15 14 0,000 0,07846114 0,11476499 ! D-ribose metabolic process GO:0006014 14 14 0,000 0,07846114 0,11467398 ! negative regulation of phosphorus metabolic process GO:0010563 14 14 0,000 0,07846114 0,11458311 GO:0045936|negative regulation of phosphate metabolic process, ! peptide transport GO:0015833 14 14 0,000 0,07846114 0,11449239 ! primary neural tube formation GO:0014020 15 14 0,000 0,07846114 0,11440181 ! peptide cross-linking GO:0018149 14 14 0,000 0,07846114 0,11431137 ! vitamin biosynthetic process GO:0009110 14 14 0,000 0,07846114 0,11422108 ! base-excision repair GO:0006284 14 14 0,000 0,07846114 0,11413093 ! response to organic cyclic substance GO:0014070 15 14 0,000 0,07846114 0,11404092 ! leukotriene metabolic process GO:0006691 14 14 0,000 0,07846114 0,11395105 ! collagen fibril organization GO:0030199 14 14 0,000 0,07846114 0,11386133 ! proteoglycan biosynthetic process GO:0030166 14 14 0,000 0,07846114 0,11377174 ! regulation of blood coagulation GO:0030193 15 14 0,000 0,07846114 0,1136823 ! positive regulation of inflammatory response GO:0050729 14 14 0,000 0,07846114 0,113593 ! group transfer coenzyme metabolic process GO:0006752 14 14 0,000 0,07846114 0,11350384 ! neuromuscular process controlling balance GO:0050885 14 14 0,000 0,07846114 0,11341481 ! aspartate family amino acid metabolic process GO:0009066 14 14 0,000 0,07846114 0,11332593 ! response to molecule of bacterial origin GO:0002237 14 14 0,000 0,07846114 0,11323719 ! negative regulation of protein polymerization GO:0032272 14 14 0,000 0,07846114 0,11314858 ! lipid catabolic process GO:0016042 82 81 1,000 0,08012552 0,11545844 ! protein import into nucleus, translocation GO:0000060 15 15 0,000 0,08382985 0,12070189 ! positive regulation of fibroblast proliferation GO:0048146 15 15 0,000 0,08382985 0,12060766 ! negative regulation of actin filament depolymerization GO:0030835 15 15 0,000 0,08382985 0,12051359 ! negative regulation of protein complex assembly GO:0031333 15 15 0,000 0,08382985 0,12041965 ! protein amino acid O-linked glycosylation GO:0006493 15 15 0,000 0,08382985 0,12032587 ! cellular polysaccharide biosynthetic process GO:0033692 15 15 0,000 0,08382985 0,12023223 ! proteoglycan metabolic process GO:0006029 15 15 0,000 0,08382985 0,12013874 ! striated muscle cell differentiation GO:0051146 16 15 0,000 0,08382985 0,12004539 ! odontogenesis of dentine-containing tooth GO:0042475 15 15 0,000 0,08382985 0,11995219 ! detection of stimulus involved in sensory perception GO:0050906 16 15 0,000 0,08382985 0,11985913 ! ovarian follicle development GO:0001541 15 15 0,000 0,08382985 0,11976621 ! antigen processing and presentation of peptide antigen GO:0048002 15 15 0,000 0,08382985 0,11967344 ! regulation of smooth muscle contraction GO:0006940 15 15 0,000 0,08382985 0,11958082 ! deoxyribonucleotide metabolic process GO:0009262 15 15 0,000 0,08382985 0,11948833 ! complement activation, classical pathway GO:0006958 15 15 0,000 0,08382985 0,11939599 ! heme metabolic process GO:0042168 15 15 0,000 0,08382985 0,1193038 ! chromosome condensation GO:0030261 15 15 0,000 0,08382985 0,11921174 ! response to starvation GO:0042594 15 15 0,000 0,08382985 0,11911983 ! response to ionizing radiation GO:0010212 16 15 0,000 0,08382985 0,11902806 ! response to mechanical stimulus GO:0009612 15 15 0,000 0,08382985 0,11893643 ! regulation of production of molecular mediator of immune response GO:0002700 15 15 0,000 0,08382985 0,11884494 ! cyclic nucleotide biosynthetic process GO:0009190 15 15 0,000 0,08382985 0,11875359 ! cholesterol biosynthetic process GO:0006695 15 15 0,000 0,08382985 0,11866238 ! phospholipid transport GO:0015914 15 15 0,000 0,08382985 0,11857131 ! leukocyte homeostasis GO:0001776 15 15 0,000 0,08382985 0,11848038 ! regulation of cytokine secretion GO:0050707 15 15 0,000 0,08382985 0,11838959 ! glutathione metabolic process GO:0006749 16 15 0,000 0,08382985 0,11829894 ! nicotinamide metabolic process GO:0006769 15 15 0,000 0,08382985 0,11820843 GO:0046496|nicotinamide nucleotide metabolic process, ! positive regulation of B cell activation GO:0050871 15 15 0,000 0,08382985 0,11811806 ! positive regulation of myeloid cell differentiation GO:0045639 16 15 0,000 0,08382985 0,11802782 ! cellular alkene metabolic process GO:0043449 15 15 0,000 0,08382985 0,11793772 ! negative regulation of transcription factor activity GO:0043433 16 15 0,000 0,08382985 0,11784776 GO:0090048|negative regulation of transcription regulator activity, ! somatic diversification of immune receptors GO:0002200 15 15 0,000 0,08382985 0,11775794 ! positive regulation of immune effector process GO:0002699 15 15 0,000 0,08382985 0,11766825 ! nitrogen compound biosynthetic process GO:0044271 86 85 1,000 0,08703176 0,12206966 ! positive regulation of cell differentiation GO:0045597 87 85 1,000 0,08703176 0,12197684 ! positive regulation of response to stimulus GO:0048584 86 85 1,000 0,08703176 0,12188415 ! hexose metabolic process GO:0019318 87 86 1,000 0,08878599 0,12424646 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 16 16 0,000 0,08916806 0,12468645 ! negative regulation of adenylate cyclase activity GO:0007194 16 16 0,000 0,08916806 0,12459191 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! alkaloid metabolic process GO:0009820 16 16 0,000 0,08916806 0,12449753 ! spliceosomal snRNP biogenesis GO:0000387 16 16 0,000 0,08916806 0,12440328 ! learning GO:0007612 16 16 0,000 0,08916806 0,12430918 ! circadian rhythm GO:0007623 16 16 0,000 0,08916806 0,12421522 ! inner ear morphogenesis GO:0042472 16 16 0,000 0,08916806 0,1241214 ! positive regulation of mitosis GO:0045840 16 16 0,000 0,08916806 0,12402773 GO:0051785|positive regulation of nuclear division, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 16 16 0,000 0,08916806 0,12393419 ! vacuole organization GO:0007033 16 16 0,000 0,08916806 0,1238408 ! positive regulation of cytoskeleton organization GO:0051495 16 16 0,000 0,08916806 0,12374754 ! vesicle targeting GO:0006903 17 16 0,000 0,08916806 0,12365443 ! fatty acid beta-oxidation GO:0006635 16 16 0,000 0,08916806 0,12356146 ! triglyceride metabolic process GO:0006641 16 16 0,000 0,08916806 0,12346862 ! iron ion homeostasis GO:0055072 16 16 0,000 0,08916806 0,12337593 ! positive regulation of cell development GO:0010720 16 16 0,000 0,08916806 0,12328337 ! regulation of myeloid leukocyte differentiation GO:0002761 17 16 0,000 0,08916806 0,12319096 ! lymphocyte proliferation GO:0046651 16 16 0,000 0,08916806 0,12309868 ! cell fate specification GO:0001708 16 16 0,000 0,08916806 0,12300654 ! pentose metabolic process GO:0019321 16 16 0,000 0,08916806 0,12291454 ! fatty acid transport GO:0015908 16 16 0,000 0,08916806 0,12282267 ! positive regulation of MAPKKK cascade GO:0043410 17 16 0,000 0,08916806 0,12273095 ! cellular response to nutrient levels GO:0031669 16 16 0,000 0,08916806 0,12263936 ! regulation of microtubule cytoskeleton organization GO:0070507 16 16 0,000 0,08916806 0,1225479 ! cofactor catabolic process GO:0051187 16 16 0,000 0,08916806 0,12245658 ! ethanolamine and derivative metabolic process GO:0042439 17 16 0,000 0,08916806 0,1223654 ! polyol metabolic process GO:0019751 16 16 0,000 0,08916806 0,12227436 ! glutamine family amino acid catabolic process GO:0009065 17 16 0,000 0,08916806 0,12218345 ! porphyrin metabolic process GO:0006778 16 16 0,000 0,08916806 0,12209267 GO:0033013|tetrapyrrole metabolic process, ! embryonic epithelial tube formation GO:0001838 17 16 0,000 0,08916806 0,12200203 GO:0001841|neural tube formation, ! regulation of JUN kinase activity GO:0043506 17 16 0,000 0,08916806 0,12191153 GO:0043507|positive regulation of JUN kinase activity, ! response to xenobiotic stimulus GO:0009410 16 16 0,000 0,08916806 0,12182115 ! regulation of coagulation GO:0050818 17 16 0,000 0,08916806 0,12173092 ! regulation of fibroblast proliferation GO:0048145 17 17 0,000 0,09447594 0,12888168 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 17 17 0,000 0,09447594 0,12878636 ! regulation of actin filament depolymerization GO:0030834 17 17 0,000 0,09447594 0,12869117 ! phosphoinositide biosynthetic process GO:0046489 17 17 0,000 0,09447594 0,12859613 ! regulation of transmembrane transport GO:0034762 17 17 0,000 0,09447594 0,12850122 ! nucleotide-excision repair, DNA damage removal GO:0000718 18 17 0,000 0,09447594 0,12840646 ! leukocyte adhesion GO:0007159 17 17 0,000 0,09447594 0,12831183 ! dicarboxylic acid metabolic process GO:0043648 18 17 0,000 0,09447594 0,12821735 ! sensory perception of smell GO:0007608 17 17 0,000 0,09447594 0,128123 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 17 17 0,000 0,09447594 0,12802879 ! embryonic skeletal system morphogenesis GO:0048704 17 17 0,000 0,09447594 0,12793472 ! cellular carbohydrate biosynthetic process GO:0034637 17 17 0,000 0,09447594 0,12784079 ! development of primary male sexual characteristics GO:0046546 17 17 0,000 0,09447594 0,127747 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 17 17 0,000 0,09447594 0,12765334 ! neural crest cell development GO:0014032 19 17 0,000 0,09447594 0,12755982 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 18 17 0,000 0,09447594 0,12746644 ! immune response-activating signal transduction GO:0002757 17 17 0,000 0,09447594 0,12737319 GO:0002764|immune response-regulating signal transduction, ! cell recognition GO:0008037 18 17 0,000 0,09447594 0,12728008 ! positive regulation of protein secretion GO:0050714 17 17 0,000 0,09447594 0,12718711 ! pyridine nucleotide metabolic process GO:0019362 17 17 0,000 0,09447594 0,12709427 ! pigmentation GO:0043473 17 17 0,000 0,09447594 0,12700157 ! myeloid leukocyte activation GO:0002274 18 17 0,000 0,09447594 0,12690901 ! adult locomotory behavior GO:0008344 17 17 0,000 0,09447594 0,12681657 ! embryonic organ development GO:0048568 17 17 0,000 0,09447594 0,12672428 ! regulation of calcium ion transport GO:0051924 17 17 0,000 0,09447594 0,12663211 ! liver development GO:0001889 17 17 0,000 0,09447594 0,12654008 ! gene silencing GO:0016458 17 17 0,000 0,09447594 0,12644819 ! negative regulation of cell cycle GO:0045786 92 91 1,000 0,09771432 0,13068758 ! visual perception GO:0007601 93 92 1,000 0,09953021 0,1330197 GO:0050953|sensory perception of light stimulus, ! energy derivation by oxidation of organic compounds GO:0015980 94 92 1,000 0,09953021 0,13292331 ! positive regulation of immune system process GO:0002684 92 92 1,000 0,09953021 0,13282706 ! mRNA export from nucleus GO:0006406 18 18 0,000 0,09975365 0,13302893 ! regulation of cellular catabolic process GO:0031329 18 18 0,000 0,09975365 0,13293274 ! icosanoid biosynthetic process GO:0046456 18 18 0,000 0,09975365 0,13283669 ! meiosis I GO:0007127 18 18 0,000 0,09975365 0,13274078 ! regulation of metal ion transport GO:0010959 18 18 0,000 0,09975365 0,13264501 ! membrane docking GO:0022406 18 18 0,000 0,09975365 0,13254938 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 18 18 0,000 0,09975365 0,13245388 ! mononuclear cell proliferation GO:0032943 18 18 0,000 0,09975365 0,13235852 GO:0070661|leukocyte proliferation, ! response to calcium ion GO:0051592 18 18 0,000 0,09975365 0,1322633 ! negative regulation of response to external stimulus GO:0032102 18 18 0,000 0,09975365 0,13216821 ! cholesterol homeostasis GO:0042632 18 18 0,000 0,09975365 0,13207327 GO:0055092|sterol homeostasis, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 18 18 0,000 0,09975365 0,13197845 ! striated muscle contraction GO:0006941 18 18 0,000 0,09975365 0,13188378 ! neutral lipid metabolic process GO:0006638 18 18 0,000 0,09975365 0,13178924 GO:0006639|acylglycerol metabolic process, ! negative regulation of DNA binding GO:0043392 19 18 0,000 0,09975365 0,13169483 ! ceramide metabolic process GO:0006672 18 18 0,000 0,09975365 0,13160056 GO:0046519|sphingoid metabolic process, ! ribonucleoside monophosphate metabolic process GO:0009161 18 18 0,000 0,09975365 0,13150643 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! telencephalon development GO:0021537 19 18 0,000 0,09975365 0,13141243 ! negative regulation of MAP kinase activity GO:0043407 18 18 0,000 0,09975365 0,13131856 ! B cell differentiation GO:0030183 18 18 0,000 0,09975365 0,13122483 ! cellular response to extracellular stimulus GO:0031668 18 18 0,000 0,09975365 0,13113123 ! regulation of microtubule-based process GO:0032886 18 18 0,000 0,09975365 0,13103777 ! negative regulation of catabolic process GO:0009895 18 18 0,000 0,09975365 0,13094443 ! symbiosis, encompassing mutualism through parasitism GO:0044403 18 18 0,000 0,09975365 0,13085124 ! establishment of vesicle localization GO:0051650 19 18 0,000 0,09975365 0,13075817 ! DNA damage checkpoint GO:0000077 19 19 0,000 0,10500137 0,13753911 ! activation of adenylate cyclase activity GO:0007190 19 19 0,000 0,10500137 0,13744143 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 19 19 0,000 0,10500137 0,13734388 GO:0006956|complement activation, ! negative regulation of DNA metabolic process GO:0051053 19 19 0,000 0,10500137 0,13724648 ! glial cell differentiation GO:0010001 19 19 0,000 0,10500137 0,13714921 ! regulation of pH GO:0006885 19 19 0,000 0,10500137 0,13705208 ! regulation of JAK-STAT cascade GO:0046425 19 19 0,000 0,10500137 0,13695508 ! feeding behavior GO:0007631 19 19 0,000 0,10500137 0,13685823 ! peroxisome organization GO:0007031 19 19 0,000 0,10500137 0,13676151 ! positive regulation of T cell proliferation GO:0042102 19 19 0,000 0,10500137 0,13666492 ! regulation of striated muscle tissue development GO:0016202 20 19 0,000 0,10500137 0,13656848 ! multicellular organismal metabolic process GO:0044236 19 19 0,000 0,10500137 0,13647217 ! peptidyl-tyrosine phosphorylation GO:0018108 20 19 0,000 0,10500137 0,13637599 ! ribonucleoside metabolic process GO:0009119 19 19 0,000 0,10500137 0,13627995 ! regulation of lymphocyte mediated immunity GO:0002706 19 19 0,000 0,10500137 0,13618405 ! positive regulation of T cell differentiation GO:0045582 19 19 0,000 0,10500137 0,13608828 ! nuclear-transcribed mRNA catabolic process GO:0000956 19 19 0,000 0,10500137 0,13599264 ! regulation of protein stability GO:0031647 19 19 0,000 0,10500137 0,13589714 ! hormone biosynthetic process GO:0042446 19 19 0,000 0,10500137 0,13580178 ! biogenic amine biosynthetic process GO:0042401 20 19 0,000 0,10500137 0,13570655 ! dorsal/ventral pattern formation GO:0009953 19 19 0,000 0,10500137 0,13561145 ! eye morphogenesis GO:0048592 19 19 0,000 0,10500137 0,13551648 ! placenta development GO:0001890 19 19 0,000 0,10500137 0,13542165 ! response to heat GO:0009408 19 19 0,000 0,10500137 0,13532695 ! vesicle localization GO:0051648 20 19 0,000 0,10500137 0,13523238 ! regulation of muscle development GO:0048634 21 20 0,000 0,11021926 0,14185343 ! negative regulation of cell adhesion GO:0007162 21 20 0,000 0,11021926 0,14175443 ! establishment or maintenance of cell polarity GO:0007163 21 20 0,000 0,11021926 0,14165558 ! negative regulation of binding GO:0051100 21 20 0,000 0,11021926 0,14155687 ! organic ether metabolic process GO:0018904 20 20 0,000 0,11021926 0,14145829 GO:0006662|glycerol ether metabolic process, ! cytoskeleton-dependent intracellular transport GO:0030705 20 20 0,000 0,11021926 0,14135985 ! neural tube development GO:0021915 21 20 0,000 0,11021926 0,14126155 ! nucleus organization GO:0006997 20 20 0,000 0,11021926 0,14116338 ! phagocytosis GO:0006909 21 20 0,000 0,11021926 0,14106535 ! positive regulation of gene-specific transcription GO:0043193 20 20 0,000 0,11021926 0,14096746 ! unsaturated fatty acid biosynthetic process GO:0006636 20 20 0,000 0,11021926 0,1408697 ! protein targeting to membrane GO:0006612 22 20 0,000 0,11021926 0,14077208 ! cyclic nucleotide metabolic process GO:0009187 20 20 0,000 0,11021926 0,14067459 ! detection of abiotic stimulus GO:0009582 21 20 0,000 0,11021926 0,14057724 ! peptidyl-tyrosine modification GO:0018212 21 20 0,000 0,11021926 0,14048002 ! lipid oxidation GO:0034440 20 20 0,000 0,11021926 0,14038293 GO:0019395|fatty acid oxidation, ! female gamete generation GO:0007292 20 20 0,000 0,11021926 0,14028598 ! negative regulation of neuron apoptosis GO:0043524 21 20 0,000 0,11021926 0,14018917 ! RNA modification GO:0009451 20 20 0,000 0,11021926 0,14009249 ! single fertilization GO:0007338 21 20 0,000 0,11021926 0,13999594 ! regulation of B cell activation GO:0050864 20 20 0,000 0,11021926 0,13989952 ! posttranscriptional regulation of gene expression GO:0010608 98 98 1,000 0,11062297 0,1403153 ! response to hormone stimulus GO:0009725 102 100 1,000 0,11439187 0,14499602 ! negative regulation of transcription from RNA polymerase II promoter GO:0000122 103 100 1,000 0,11439187 0,14489637 ! mitotic sister chromatid segregation GO:0000070 21 21 0,000 0,11540749 0,14608242 ! mRNA catabolic process GO:0006402 21 21 0,000 0,11540749 0,14598216 ! positive regulation of adenylate cyclase activity GO:0045762 21 21 0,000 0,11540749 0,14588203 GO:0051349|positive regulation of lyase activity, GO:0031281|positive regulation of cyclase activity, ! protein amino acid lipidation GO:0006497 21 21 0,000 0,11540749 0,14578205 ! receptor-mediated endocytosis GO:0006898 21 21 0,000 0,11540749 0,1456822 ! Notch signaling pathway GO:0007219 22 21 0,000 0,11540749 0,14558248 ! morphogenesis of embryonic epithelium GO:0016331 22 21 0,000 0,11540749 0,1454829 ! ear morphogenesis GO:0042471 21 21 0,000 0,11540749 0,14538346 ! organic anion transport GO:0015711 21 21 0,000 0,11540749 0,14528416 ! cholesterol transport GO:0030301 21 21 0,000 0,11540749 0,14518499 GO:0015918|sterol transport, ! spliceosome assembly GO:0000245 22 21 0,000 0,11540749 0,14508595 ! regulation of Rab protein signal transduction GO:0032483 21 21 0,000 0,11540749 0,14498705 GO:0032313|regulation of Rab GTPase activity, ! DNA integrity checkpoint GO:0031570 21 21 0,000 0,11540749 0,14488829 ! regulation of leukocyte mediated immunity GO:0002703 21 21 0,000 0,11540749 0,14478966 ! regulation of multicellular organism growth GO:0040014 21 21 0,000 0,11540749 0,14469116 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 21 21 0,000 0,11540749 0,1445928 ! regulation of proteolysis GO:0030162 21 21 0,000 0,11540749 0,14449457 ! negative regulation of hydrolase activity GO:0051346 21 21 0,000 0,11540749 0,14439647 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 21 21 0,000 0,11540749 0,14429851 ! RNA export from nucleus GO:0006405 22 22 0,000 0,12056622 0,15064647 ! positive regulation of DNA metabolic process GO:0051054 23 22 0,000 0,12056622 0,1505444 ! sister chromatid segregation GO:0000819 22 22 0,000 0,12056622 0,15044248 ! cellular amide metabolic process GO:0043603 22 22 0,000 0,12056622 0,15034069 ! regulation of ion transport GO:0043269 22 22 0,000 0,12056622 0,15023904 ! odontogenesis GO:0042476 22 22 0,000 0,12056622 0,15013753 ! positive regulation of lymphocyte proliferation GO:0050671 22 22 0,000 0,12056622 0,15003615 GO:0032946|positive regulation of mononuclear cell proliferation, GO:0070665|positive regulation of leukocyte proliferation, GO:0070668|positive regulation of mast cell proliferation, ! hormone-mediated signaling GO:0009755 22 22 0,000 0,12056622 0,14993491 ! embryonic skeletal system development GO:0048706 22 22 0,000 0,12056622 0,14983381 ! maintenance of protein location in cell GO:0032507 23 22 0,000 0,12056622 0,14973284 ! ovulation cycle process GO:0022602 22 22 0,000 0,12056622 0,14963201 ! spindle organization GO:0007051 22 22 0,000 0,12056622 0,14953132 ! pigment biosynthetic process GO:0046148 22 22 0,000 0,12056622 0,14943076 ! cell chemotaxis GO:0060326 23 22 0,000 0,12056622 0,14933033 GO:0030595|leukocyte chemotaxis, ! respiratory gaseous exchange GO:0007585 22 22 0,000 0,12056622 0,14923005 ! erythrocyte differentiation GO:0030218 23 22 0,000 0,12056622 0,14912989 ! male sex differentiation GO:0046661 22 22 0,000 0,12056622 0,14902987 ! sterol biosynthetic process GO:0016126 22 22 0,000 0,12056622 0,14892998 ! regulation of adaptive immune response GO:0002819 22 22 0,000 0,12056622 0,14883023 ! detection of external stimulus GO:0009581 23 22 0,000 0,12056622 0,14873061 ! neuron migration GO:0001764 22 22 0,000 0,12056622 0,14863113 ! regulation of Wnt receptor signaling pathway GO:0030111 23 22 0,000 0,12056622 0,14853178 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 22 22 0,000 0,12056622 0,14843256 ! positive regulation of lymphocyte differentiation GO:0045621 22 22 0,000 0,12056622 0,14833347 ! fatty acid catabolic process GO:0009062 23 22 0,000 0,12056622 0,14823451 ! aerobic respiration GO:0009060 22 22 0,000 0,12056622 0,14813569 ! cytokine production GO:0001816 22 22 0,000 0,12056622 0,148037 ! cytokinesis GO:0000910 23 22 0,000 0,12056622 0,14793844 ! pyrimidine nucleotide metabolic process GO:0006220 22 22 0,000 0,12056622 0,14784001 ! epithelial cell differentiation GO:0030855 23 23 0,000 0,12569561 0,15402726 ! regulation of hormone secretion GO:0046883 23 23 0,000 0,12569561 0,15392492 ! response to estrogen stimulus GO:0043627 23 23 0,000 0,12569561 0,15382271 ! negative regulation of protein complex disassembly GO:0043242 23 23 0,000 0,12569561 0,15372064 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 23 23 0,000 0,12569561 0,1536187 ! mitotic cell cycle checkpoint GO:0007093 24 23 0,000 0,12569561 0,1535169 ! induction of apoptosis by extracellular signals GO:0008624 23 23 0,000 0,12569561 0,15341523 ! regulation of ARF protein signal transduction GO:0032012 23 23 0,000 0,12569561 0,1533137 ! lipoprotein biosynthetic process GO:0042158 23 23 0,000 0,12569561 0,1532123 ! positive regulation of growth GO:0045927 23 23 0,000 0,12569561 0,15311104 ! female gonad development GO:0008585 23 23 0,000 0,12569561 0,15300991 ! monovalent inorganic cation homeostasis GO:0055067 23 23 0,000 0,12569561 0,15290891 ! lipid homeostasis GO:0055088 23 23 0,000 0,12569561 0,15280805 ! Rho protein signal transduction GO:0007266 24 23 0,000 0,12569561 0,15270732 ! regulation of JNK cascade GO:0046328 25 23 0,000 0,12569561 0,15260672 ! mitochondrial transport GO:0006839 24 24 0,000 0,13079582 0,15869434 ! gliogenesis GO:0042063 24 24 0,000 0,13079582 0,15858993 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 26 24 0,000 0,13079582 0,15848567 ! glucose homeostasis GO:0042593 24 24 0,000 0,13079582 0,15838154 GO:0033500|carbohydrate homeostasis, ! heterocycle biosynthetic process GO:0018130 24 24 0,000 0,13079582 0,15827754 ! T cell differentiation GO:0030217 24 24 0,000 0,13079582 0,15817369 ! nucleotide catabolic process GO:0009166 24 24 0,000 0,13079582 0,15806997 ! erythrocyte homeostasis GO:0034101 25 24 0,000 0,13079582 0,15796638 ! ovulation cycle GO:0042698 24 24 0,000 0,13079582 0,15786293 ! fertilization GO:0009566 25 24 0,000 0,13079582 0,15775962 ! maintenance of protein location GO:0045185 25 24 0,000 0,13079582 0,15765644 ! oxidoreduction coenzyme metabolic process GO:0006733 24 24 0,000 0,13079582 0,1575534 ! regulation of actin filament polymerization GO:0030833 25 25 0,000 0,13586702 0,16355514 ! negative regulation of secretion GO:0051048 26 25 0,000 0,13586702 0,16344838 ! protein amino acid N-linked glycosylation GO:0006487 25 25 0,000 0,13586702 0,16334176 ! regulation of gene-specific transcription GO:0032583 25 25 0,000 0,13586702 0,16323528 ! sensory perception of chemical stimulus GO:0007606 25 25 0,000 0,13586702 0,16312894 ! cellular component disassembly GO:0022411 26 25 0,000 0,13586702 0,16302274 ! endosome transport GO:0016197 25 25 0,000 0,13586702 0,16291667 ! development of primary female sexual characteristics GO:0046545 25 25 0,000 0,13586702 0,16281074 GO:0046660|female sex differentiation, ! polysaccharide biosynthetic process GO:0000271 25 25 0,000 0,13586702 0,16270495 ! excretion GO:0007588 25 25 0,000 0,13586702 0,1625993 ! generation of a signal involved in cell-cell signaling GO:0003001 27 25 0,000 0,13586702 0,16249379 ! heart morphogenesis GO:0003007 25 25 0,000 0,13586702 0,16238841 ! icosanoid metabolic process GO:0006690 25 25 0,000 0,13586702 0,16228317 ! regulation of endocytosis GO:0030100 25 25 0,000 0,13586702 0,16217806 ! JAK-STAT cascade GO:0007259 26 25 0,000 0,13586702 0,16207309 ! positive regulation of cytokine production GO:0001819 25 25 0,000 0,13586702 0,16196826 ! positive regulation of defense response GO:0031349 26 26 0,000 0,14090938 0,1678707 ! transforming growth factor beta receptor signaling pathway GO:0007179 26 26 0,000 0,14090938 0,16776226 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 26 26 0,000 0,14090938 0,16765396 ! induction of apoptosis by intracellular signals GO:0008629 26 26 0,000 0,14090938 0,16754579 ! cellular defense response GO:0006968 26 26 0,000 0,14090938 0,16743777 ! positive regulation of cytokine biosynthetic process GO:0042108 26 26 0,000 0,14090938 0,16732988 ! double-strand break repair GO:0006302 27 26 0,000 0,14090938 0,16722214 ! regulation of protein secretion GO:0050708 26 26 0,000 0,14090938 0,16711453 ! germ cell development GO:0007281 27 26 0,000 0,14090938 0,16700706 ! regulation of blood vessel size GO:0050880 27 26 0,000 0,14090938 0,16689973 GO:0035150|regulation of tube size, ! pigment metabolic process GO:0042440 26 26 0,000 0,14090938 0,16679254 ! maintenance of location in cell GO:0051651 27 26 0,000 0,14090938 0,16668548 ! chloride transport GO:0006821 27 27 0,000 0,14592304 0,17250555 ! regulation of neurotransmitter levels GO:0001505 31 27 0,000 0,14592304 0,17239497 ! learning or memory GO:0007611 28 27 0,000 0,14592304 0,17228453 ! monocarboxylic acid transport GO:0015718 27 27 0,000 0,14592304 0,17217423 ! cAMP-mediated signaling GO:0019933 27 27 0,000 0,14592304 0,17206408 ! peptide metabolic process GO:0006518 29 27 0,000 0,14592304 0,17195406 ! activation of caspase activity GO:0006919 27 27 0,000 0,14592304 0,17184419 ! inner ear development GO:0048839 27 27 0,000 0,14592304 0,17173445 ! defense response to bacterium GO:0042742 27 27 0,000 0,14592304 0,17162486 ! isoprenoid metabolic process GO:0006720 27 27 0,000 0,14592304 0,1715154 ! glutamine family amino acid metabolic process GO:0009064 28 27 0,000 0,14592304 0,17140609 ! cell growth GO:0016049 27 27 0,000 0,14592304 0,17129691 ! stress-activated protein kinase signaling pathway GO:0031098 28 28 0,000 0,15090816 0,17703612 GO:0007254|JNK cascade, ! neuromuscular process GO:0050905 28 28 0,000 0,15090816 0,1769235 ! regulation of muscle contraction GO:0006937 28 28 0,000 0,15090816 0,17681103 ! unsaturated fatty acid metabolic process GO:0033559 28 28 0,000 0,15090816 0,17669869 ! sulfur compound biosynthetic process GO:0044272 28 28 0,000 0,15090816 0,1765865 ! keratinocyte differentiation GO:0030216 28 28 0,000 0,15090816 0,17647446 ! developmental growth GO:0048589 28 28 0,000 0,15090816 0,17636255 ! cartilage development GO:0051216 29 28 0,000 0,15090816 0,17625079 ! glycerophospholipid biosynthetic process GO:0046474 30 29 0,000 0,15586492 0,18192466 ! phosphoinositide metabolic process GO:0030384 29 29 0,000 0,15586492 0,18180952 ! leukocyte migration GO:0050900 30 29 0,000 0,15586492 0,18169452 ! antigen processing and presentation GO:0019882 29 29 0,000 0,15586492 0,18157967 ! DNA-dependent DNA replication GO:0006261 29 29 0,000 0,15586492 0,18146497 ! tRNA processing GO:0008033 29 29 0,000 0,15586492 0,1813504 ! adult behavior GO:0030534 30 29 0,000 0,15586492 0,18123599 ! regulation of protein polymerization GO:0032271 29 29 0,000 0,15586492 0,18112172 ! transition metal ion transport GO:0000041 31 30 0,000 0,16079345 0,18673115 ! RNA catabolic process GO:0006401 30 30 0,000 0,16079345 0,18661356 ! ER to Golgi vesicle-mediated transport GO:0006888 30 30 0,000 0,16079345 0,18649612 ! positive regulation of peptidase activity GO:0010952 30 30 0,000 0,16079345 0,18637883 GO:0043280|positive regulation of caspase activity, ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 30 30 0,000 0,16079345 0,18626168 ! neuropeptide signaling pathway GO:0007218 30 30 0,000 0,16079345 0,18614468 ! regulation of protein complex disassembly GO:0043244 30 30 0,000 0,16079345 0,18602783 ! positive regulation of protein amino acid phosphorylation GO:0001934 30 30 0,000 0,16079345 0,18591112 ! skeletal system morphogenesis GO:0048705 31 30 0,000 0,16079345 0,18579457 ! response to temperature stimulus GO:0009266 30 30 0,000 0,16079345 0,18567815 ! immunoglobulin mediated immune response GO:0016064 30 30 0,000 0,16079345 0,18556189 GO:0019724|B cell mediated immunity, ! regulation of inflammatory response GO:0050727 30 30 0,000 0,16079345 0,18544577 ! water-soluble vitamin metabolic process GO:0006767 30 30 0,000 0,16079345 0,18532979 ! vesicle organization GO:0016050 30 30 0,000 0,16079345 0,18521396 ! cellular amino acid derivative biosynthetic process GO:0042398 31 30 0,000 0,16079345 0,18509827 ! establishment of organelle localization GO:0051656 31 30 0,000 0,16079345 0,18498273 ! regulation of translational initiation GO:0006446 31 31 0,000 0,16569393 0,1905015 ! B cell activation GO:0042113 31 31 0,000 0,16569393 0,19038274 ! negative regulation of cytoskeleton organization GO:0051494 32 31 0,000 0,16569393 0,19026412 ! lipoprotein metabolic process GO:0042157 31 31 0,000 0,16569393 0,19014565 ! ion transmembrane transport GO:0034220 31 31 0,000 0,16569393 0,19002732 GO:0015985|energy coupled proton transport, down electrochemical gradient, GO:0015986|ATP synthesis coupled proton transport, ! aging GO:0007568 32 31 0,000 0,16569393 0,18990915 ! glycerolipid biosynthetic process GO:0045017 32 31 0,000 0,16569393 0,18979112 ! digestion GO:0007586 31 31 0,000 0,16569393 0,18967324 ! nucleoside metabolic process GO:0009116 31 31 0,000 0,16569393 0,1895555 ! regulation of DNA replication GO:0006275 32 31 0,000 0,16569393 0,18943791 ! regulation of heart contraction GO:0008016 31 31 0,000 0,16569393 0,18932047 ! sphingolipid metabolic process GO:0006665 31 31 0,000 0,16569393 0,18920317 ! camera-type eye development GO:0043010 31 31 0,000 0,16569393 0,18908601 ! extracellular matrix organization GO:0030198 31 31 0,000 0,16569393 0,188969 ! ribonucleoprotein complex assembly GO:0022618 32 31 0,000 0,16569393 0,18885214 ! epidermal cell differentiation GO:0009913 31 31 0,000 0,16569393 0,18873542 ! negative regulation of cell growth GO:0030308 32 32 0,000 0,1705665 0,19416557 ! cell redox homeostasis GO:0045454 32 32 0,000 0,1705665 0,19404572 ! lipid modification GO:0030258 32 32 0,000 0,1705665 0,19392601 ! glycosaminoglycan metabolic process GO:0030203 34 32 0,000 0,1705665 0,19380645 ! regulation of vesicle-mediated transport GO:0060627 33 32 0,000 0,1705665 0,19368704 ! cell maturation GO:0048469 32 32 0,000 0,1705665 0,19356777 ! nuclear export GO:0051168 32 32 0,000 0,1705665 0,19344865 ! protein maturation by peptide bond cleavage GO:0051605 32 32 0,000 0,1705665 0,19332968 ! maintenance of location GO:0051235 33 32 0,000 0,1705665 0,19321085 ! negative regulation of cell size GO:0045792 33 33 0,000 0,17541132 0,19857682 ! regulation of cellular response to stress GO:0080135 35 33 0,000 0,17541132 0,19845492 ! amino acid transport GO:0006865 33 33 0,000 0,17541132 0,19833317 ! activation of protein kinase activity GO:0032147 35 33 0,000 0,17541132 0,19821157 ! regulation of protein complex assembly GO:0043254 33 33 0,000 0,17541132 0,19809011 ! membrane lipid metabolic process GO:0006643 33 33 0,000 0,17541132 0,19796881 ! regulation of actin polymerization or depolymerization GO:0008064 33 33 0,000 0,17541132 0,19784765 ! regulation of neuron apoptosis GO:0043523 34 33 0,000 0,17541132 0,19772665 ! regulation of actin filament length GO:0030832 34 34 0,000 0,18022855 0,20303253 ! response to metal ion GO:0010038 34 34 0,000 0,18022855 0,2029085 ! ear development GO:0043583 34 34 0,000 0,18022855 0,20278462 ! muscle cell differentiation GO:0042692 35 34 0,000 0,18022855 0,2026609 ! coenzyme biosynthetic process GO:0009108 34 34 0,000 0,18022855 0,20253733 ! nucleoside monophosphate biosynthetic process GO:0009124 34 34 0,000 0,18022855 0,2024139 ! regulation of lipid metabolic process GO:0019216 34 34 0,000 0,18022855 0,20229063 ! secondary metabolic process GO:0019748 34 34 0,000 0,18022855 0,20216751 ! negative regulation of response to stimulus GO:0048585 34 34 0,000 0,18022855 0,20204453 ! detection of stimulus GO:0051606 36 34 0,000 0,18022855 0,20192171 ! acute inflammatory response GO:0002526 35 35 0,000 0,18501833 0,20716208 ! regulation of cellular component size GO:0032535 35 35 0,000 0,18501833 0,2070363 ! regulation of cytokine biosynthetic process GO:0042035 35 35 0,000 0,18501833 0,20691067 ! multicellular organism reproduction GO:0032504 36 35 0,000 0,18501833 0,20678519 GO:0048609|reproductive process in a multicellular organism, ! inorganic anion transport GO:0015698 35 35 0,000 0,18501833 0,20665987 ! response to steroid hormone stimulus GO:0048545 35 35 0,000 0,18501833 0,2065347 ! regulation of immune effector process GO:0002697 35 35 0,000 0,18501833 0,20640968 ! hydrogen transport GO:0006818 36 36 0,000 0,18978083 0,21159471 GO:0015992|proton transport, ! response to inorganic substance GO:0010035 36 36 0,000 0,18978083 0,21146678 ! aminoglycan metabolic process GO:0006022 38 36 0,000 0,18978083 0,21133901 ! regulation of mitosis GO:0007088 37 36 0,000 0,18978083 0,21121139 GO:0051783|regulation of nuclear division, ! female pregnancy GO:0007565 37 36 0,000 0,18978083 0,21108392 ! positive regulation of organelle organization GO:0010638 36 36 0,000 0,18978083 0,21095661 ! heterocycle catabolic process GO:0046700 36 36 0,000 0,18978083 0,21082945 ! integrin-mediated signaling pathway GO:0007229 36 36 0,000 0,18978083 0,21070245 ! gonad development GO:0008406 36 36 0,000 0,18978083 0,21057559 ! activation of immune response GO:0002253 36 36 0,000 0,18978083 0,21044889 ! coagulation GO:0050817 39 36 0,000 0,18978083 0,21032235 GO:0007596|blood coagulation, ! regulation of adenylate cyclase activity GO:0045761 37 37 0,000 0,19451618 0,2154407 GO:0031279|regulation of cyclase activity, GO:0051339|regulation of lyase activity, ! meiosis GO:0007126 37 37 0,000 0,19451618 0,2153113 GO:0051327|M phase of meiotic cell cycle, ! negative regulation of protein kinase activity GO:0006469 37 37 0,000 0,19451618 0,21518206 ! lymphocyte mediated immunity GO:0002449 37 37 0,000 0,19451618 0,21505298 ! eye development GO:0001654 37 37 0,000 0,19451618 0,21492405 ! negative regulation of growth GO:0045926 37 37 0,000 0,19451618 0,21479528 ! DNA damage response, signal transduction GO:0042770 37 37 0,000 0,19451618 0,21466666 ! ATP synthesis coupled electron transport GO:0042773 37 37 0,000 0,19451618 0,21453819 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! cellular amino acid catabolic process GO:0009063 38 37 0,000 0,19451618 0,21440988 ! regulation of Rho protein signal transduction GO:0035023 37 37 0,000 0,19451618 0,21428172 ! positive regulation of secretion GO:0051047 39 38 0,000 0,19922455 0,21933742 ! neurotransmitter transport GO:0006836 40 38 0,000 0,19922455 0,21920647 ! exocytosis GO:0006887 40 38 0,000 0,19922455 0,21907568 ! negative regulation of kinase activity GO:0033673 38 38 0,000 0,19922455 0,21894504 ! chromosome segregation GO:0007059 38 38 0,000 0,19922455 0,21881456 ! meiotic cell cycle GO:0051321 38 38 0,000 0,19922455 0,21868424 ! regulation of cAMP biosynthetic process GO:0030817 39 39 0,000 0,20390607 0,22368982 ! hemostasis GO:0007599 42 39 0,000 0,20390607 0,22355675 ! positive regulation of protein modification process GO:0031401 39 39 0,000 0,20390607 0,22342384 ! activation of MAPK activity GO:0000187 39 39 0,000 0,20390607 0,22329108 ! response to unfolded protein GO:0006986 39 39 0,000 0,20390607 0,22315849 ! nucleoside monophosphate metabolic process GO:0009123 39 39 0,000 0,20390607 0,22302605 ! fatty acid biosynthetic process GO:0006633 39 39 0,000 0,20390607 0,22289377 ! nucleotide-excision repair GO:0006289 40 39 0,000 0,20390607 0,22276165 ! cytokine-mediated signaling pathway GO:0019221 39 39 0,000 0,20390607 0,22262968 ! regulation of MAPKKK cascade GO:0043408 41 39 0,000 0,20390607 0,22249787 ! positive regulation of T cell activation GO:0050870 39 39 0,000 0,20390607 0,22236621 ! developmental maturation GO:0021700 39 39 0,000 0,20390607 0,22223471 ! lymphocyte differentiation GO:0030098 39 39 0,000 0,20390607 0,22210337 ! regulation of cAMP metabolic process GO:0030814 40 40 0,000 0,20856091 0,22703944 ! DNA catabolic process GO:0006308 41 40 0,000 0,20856091 0,22690541 ! negative regulation of transferase activity GO:0051348 40 40 0,000 0,20856091 0,22677154 ! myeloid cell differentiation GO:0030099 42 40 0,000 0,20856091 0,22663783 ! organelle localization GO:0051640 41 40 0,000 0,20856091 0,22650428 ! regulation of nucleotide biosynthetic process GO:0030808 41 41 0,000 0,21318921 0,23139442 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! cell cycle checkpoint GO:0000075 42 41 0,000 0,21318921 0,23125822 ! amine catabolic process GO:0009310 42 41 0,000 0,21318921 0,23112219 ! elevation of cytosolic calcium ion concentration GO:0007204 41 41 0,000 0,21318921 0,23098631 ! phospholipid biosynthetic process GO:0008654 42 41 0,000 0,21318921 0,2308506 ! leukocyte mediated immunity GO:0002443 41 41 0,000 0,21318921 0,23071504 ! regulation of Ras GTPase activity GO:0032318 41 41 0,000 0,21318921 0,23057965 ! respiratory electron transport chain GO:0022904 43 42 0,000 0,21779112 0,23541879 ! regulation of cyclic nucleotide metabolic process GO:0030799 42 42 0,000 0,21779112 0,23528079 ! cytosolic calcium ion homeostasis GO:0051480 42 42 0,000 0,21779112 0,23514296 ! development of primary sexual characteristics GO:0045137 42 42 0,000 0,21779112 0,23500529 ! negative regulation of ligase activity GO:0051352 43 42 0,000 0,21779112 0,23486778 GO:0051444|negative regulation of ubiquitin-protein ligase activity, GO:0051436|negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle, ! response to protein stimulus GO:0051789 42 42 0,000 0,21779112 0,23473043 ! forebrain development GO:0030900 43 42 0,000 0,21779112 0,23459324 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 42 42 0,000 0,21779112 0,23445621 ! reproductive structure development GO:0048608 43 43 0,000 0,22236678 0,23924225 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 43 43 0,000 0,22236678 0,23910267 ! mitochondrion organization GO:0007005 44 43 0,000 0,22236678 0,23896325 ! homeostasis of number of cells GO:0048872 44 43 0,000 0,22236678 0,23882399 ! regulation of nucleotide metabolic process GO:0006140 43 43 0,000 0,22236678 0,2386849 ! humoral immune response GO:0006959 44 44 0,000 0,22691634 0,24342655 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 45 44 0,000 0,22691634 0,24328494 ! negative regulation of organelle organization GO:0010639 45 44 0,000 0,22691634 0,24314349 ! vitamin metabolic process GO:0006766 44 44 0,000 0,22691634 0,24300221 ! positive regulation of lymphocyte activation GO:0051251 44 44 0,000 0,22691634 0,2428611 ! regulation of actin cytoskeleton organization GO:0032956 46 45 0,000 0,23143994 0,2475588 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 46 45 0,000 0,23143994 0,2474152 ! steroid biosynthetic process GO:0006694 46 45 0,000 0,23143994 0,24727177 ! protein processing GO:0016485 45 45 0,000 0,23143994 0,24712851 ! regulation of actin filament-based process GO:0032970 47 46 0,000 0,23593773 0,25178531 ! cyclic-nucleotide-mediated signaling GO:0019935 46 46 0,000 0,23593773 0,2516396 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 47 46 0,000 0,23593773 0,25149406 ! positive regulation of ligase activity GO:0051351 47 46 0,000 0,23593773 0,25134869 ! sex differentiation GO:0007548 47 47 0,000 0,24040985 0,25596497 ! amine transport GO:0015837 47 47 0,000 0,24040985 0,25581718 ! rhythmic process GO:0048511 47 47 0,000 0,24040985 0,25566957 ! regulation of ubiquitin-protein ligase activity GO:0051438 49 48 0,000 0,24485645 0,26024823 ! regulation of cell cycle process GO:0010564 50 48 0,000 0,24485645 0,26009824 ! glycerophospholipid metabolic process GO:0006650 49 48 0,000 0,24485645 0,25994841 ! DNA recombination GO:0006310 48 48 0,000 0,24485645 0,25979876 ! leukocyte differentiation GO:0002521 50 49 0,000 0,24927767 0,26433759 ! response to bacterium GO:0009617 50 49 0,000 0,24927767 0,26418559 ! regulation of ligase activity GO:0051340 50 49 0,000 0,24927767 0,26403376 ! cofactor biosynthetic process GO:0051188 49 49 0,000 0,24927767 0,2638821 ! positive regulation of cell activation GO:0050867 49 49 0,000 0,24927767 0,26373062 GO:0002696|positive regulation of leukocyte activation, ! regulation of defense response GO:0031347 50 50 0,000 0,25367364 0,26822749 ! regulation of DNA metabolic process GO:0051052 51 50 0,000 0,25367364 0,26807369 ! chromatin assembly GO:0031497 50 50 0,000 0,25367364 0,26792007 GO:0006334|nucleosome assembly, ! T cell activation GO:0042110 51 50 0,000 0,25367364 0,26776662 ! nitrogen compound catabolic process GO:0044270 51 50 0,000 0,25367364 0,26761335 ! biogenic amine metabolic process GO:0006576 52 51 0,000 0,25804451 0,27206867 ! positive regulation of immune response GO:0050778 51 51 0,000 0,25804451 0,27191311 ! protein-DNA complex assembly GO:0065004 51 51 0,000 0,25804451 0,27175773 ! ATP biosynthetic process GO:0006754 51 51 0,000 0,25804451 0,27160253 ! protein maturation GO:0051604 51 51 0,000 0,25804451 0,27144751 ! cholesterol metabolic process GO:0008203 52 52 0,000 0,26239042 0,27586169 ! cell fate commitment GO:0045165 52 52 0,000 0,26239042 0,27570442 ! regulation of GTPase activity GO:0043087 53 52 0,000 0,26239042 0,27554732 ! regulation of body fluid levels GO:0050878 55 52 0,000 0,26239042 0,2753904 ! sodium ion transport GO:0006814 53 53 0,000 0,26671151 0,27976625 ! protein amino acid dephosphorylation GO:0006470 55 54 0,000 0,27100791 0,28411125 ! response to virus GO:0009615 54 54 0,000 0,27100791 0,28394973 ! sulfur metabolic process GO:0006790 55 54 0,000 0,27100791 0,2837884 ! nucleosome organization GO:0034728 55 55 0,000 0,27527977 0,28809802 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 55 55 0,000 0,27527977 0,28793451 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! microtubule cytoskeleton organization GO:0000226 55 55 0,000 0,27527977 0,28777119 ! ribonucleoside triphosphate biosynthetic process GO:0009201 56 56 0,000 0,27952721 0,29204572 ! reproductive developmental process GO:0003006 56 56 0,000 0,27952721 0,29188025 ! ATP metabolic process GO:0046034 57 57 0,000 0,28375038 0,29612228 ! nucleoside triphosphate biosynthetic process GO:0009142 57 57 0,000 0,28375038 0,2959547 ! innate immune response GO:0045087 58 58 0,000 0,28794941 0,30016446 ! dephosphorylation GO:0016311 60 59 0,000 0,29212444 0,30434445 ! carboxylic acid transport GO:0046942 59 59 0,000 0,29212444 0,30417251 GO:0015849|organic acid transport, ! sterol metabolic process GO:0016125 59 59 0,000 0,29212444 0,30400075 ! cellular aromatic compound metabolic process GO:0006725 60 59 0,000 0,29212444 0,3038292 ! immune effector process GO:0002252 59 59 0,000 0,29212444 0,30365783 ! potassium ion transport GO:0006813 60 60 0,000 0,29627559 0,30779927 ! negative regulation of cellular protein metabolic process GO:0032269 60 60 0,000 0,29627559 0,30762587 ! protein polymerization GO:0051258 65 60 0,000 0,29627559 0,30745265 ! cellular respiration GO:0045333 62 61 0,000 0,30040301 0,31156035 ! proteasomal protein catabolic process GO:0010498 62 61 0,000 0,30040301 0,31138512 GO:0043161|proteasomal ubiquitin-dependent protein catabolic process, ! carboxylic acid catabolic process GO:0046395 63 61 0,000 0,30040301 0,31121008 GO:0016054|organic acid catabolic process, ! positive regulation of cellular protein metabolic process GO:0032270 61 61 0,000 0,30040301 0,31103525 ! lipid transport GO:0006869 62 62 0,000 0,30450682 0,31510728 ! purine ribonucleoside triphosphate metabolic process GO:0009205 62 62 0,000 0,30450682 0,31493045 ! regulation of cellular component biogenesis GO:0044087 63 62 0,000 0,30450682 0,31475382 ! regulation of secretion GO:0051046 65 63 0,000 0,30858715 0,31879267 ! ribonucleoside triphosphate metabolic process GO:0009199 63 63 0,000 0,30858715 0,31861407 ! purine nucleoside triphosphate metabolic process GO:0009144 63 63 0,000 0,30858715 0,31843568 ! glycerolipid metabolic process GO:0046486 65 64 0,000 0,31264414 0,32244161 ! regulation of cytoskeleton organization GO:0051493 66 64 0,000 0,31264414 0,32226127 ! anion transport GO:0006820 65 65 0,000 0,31667792 0,32623667 ! positive regulation of cellular component organization GO:0051130 65 65 0,000 0,31667792 0,32605442 ! protein amino acid glycosylation GO:0006486 66 66 0,000 0,32068862 0,32999951 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! nucleoside triphosphate metabolic process GO:0009141 66 66 0,000 0,32068862 0,32981536 ! DNA packaging GO:0006323 66 66 0,000 0,32068862 0,32963141 ! negative regulation of protein metabolic process GO:0051248 66 66 0,000 0,32068862 0,32944767 ! Golgi vesicle transport GO:0048193 67 67 0,000 0,32467636 0,33335851 ! muscle contraction GO:0006936 67 67 0,000 0,32467636 0,3331729 ! Ras protein signal transduction GO:0007265 69 67 0,000 0,32467636 0,33298749 ! purine ribonucleotide biosynthetic process GO:0009152 68 68 0,000 0,32864127 0,33686644 ! chromatin assembly or disassembly GO:0006333 68 68 0,000 0,32864127 0,33667919 ! regulation of cell size GO:0008361 68 68 0,000 0,32864127 0,33649214 ! regulation of translation GO:0006417 69 69 0,000 0,33258348 0,34033945 ! sensory perception of sound GO:0007605 71 69 0,000 0,33258348 0,34015058 GO:0050954|sensory perception of mechanical stimulus, ! regulation of mitotic cell cycle GO:0007346 72 69 0,000 0,33258348 0,33996193 ! growth GO:0040007 70 70 0,000 0,33650312 0,34377785 ! oxidative phosphorylation GO:0006119 71 71 0,000 0,34040031 0,34756663 ! calcium ion homeostasis GO:0055074 71 71 0,000 0,34040031 0,34737418 GO:0006874|cellular calcium ion homeostasis, ! secretion by cell GO:0032940 75 72 0,000 0,34427518 0,35113401 ! muscle system process GO:0003012 72 72 0,000 0,34427518 0,3509398 ! sensory organ development GO:0007423 72 72 0,000 0,34427518 0,3507458 ! regulation of cytokine production GO:0001817 72 72 0,000 0,34427518 0,35055202 ! electron transport chain GO:0022900 75 74 0,000 0,35195845 0,35817749 ! coenzyme metabolic process GO:0006732 75 74 0,000 0,35195845 0,35797982 ! ribonucleotide biosynthetic process GO:0009260 75 75 0,000 0,3557671 0,36165403 ! purine ribonucleotide metabolic process GO:0009150 75 75 0,000 0,3557671 0,36145467 ! cellular metal ion homeostasis GO:0006875 77 77 0,000 0,36331904 0,36892396 ! microtubule-based movement GO:0007018 82 78 0,000 0,36706257 0,37251999 ! metal ion homeostasis GO:0055065 78 78 0,000 0,36706257 0,37231498 ! regulation of immune response GO:0050776 78 78 0,000 0,36706257 0,37211018 ! glycoprotein biosynthetic process GO:0009101 80 80 0,000 0,37448536 0,37942634 ! MAPKKK cascade GO:0000165 82 81 0,000 0,37816485 0,38294386 ! lymphocyte activation GO:0046649 82 81 0,000 0,37816485 0,38273357 ! ribonucleotide metabolic process GO:0009259 83 83 0,000 0,38546065 0,38990339 ! cellular amino acid derivative metabolic process GO:0006575 87 84 0,000 0,38907718 0,39334572 ! organophosphate metabolic process GO:0019637 87 86 0,000 0,3962481 0,40037569 GO:0006644|phospholipid metabolic process, ! male gamete generation GO:0048232 90 88 0,000 0,40333693 0,40731505 GO:0007283|spermatogenesis, ! purine nucleotide biosynthetic process GO:0006164 88 88 0,000 0,40333693 0,40709198 ! chemotaxis GO:0006935 90 89 0,000 0,40685085 0,41041385 GO:0042330|taxis, ! cellular di-, tri-valent inorganic cation homeostasis GO:0030005 89 89 0,000 0,40685085 0,41018934 ! regulation of Ras protein signal transduction GO:0046578 90 90 0,000 0,41034458 0,41348555 ! brain development GO:0007420 91 90 0,000 0,41034458 0,4132596 ! di-, tri-valent inorganic cation homeostasis GO:0055066 91 91 0,000 0,41381825 0,41653033 ! DNA replication GO:0006260 91 91 0,000 0,41381825 0,41630297 ! fatty acid metabolic process GO:0006631 93 92 0,000 0,41727197 0,41954841 ! regulation of response to stress GO:0080134 97 94 0,000 0,42411998 0,42620127 ! epidermis development GO:0008544 94 94 0,000 0,42411998 0,425969 ! cofactor metabolic process GO:0051186 95 94 0,000 0,42411998 0,42573699 ! regulation of cell growth GO:0001558 97 96 0,000 0,4308895 0,43229687 ! endocytosis GO:0006897 99 98 0,000 0,43758142 0,43877179 GO:0010324|membrane invagination, ! glycoprotein metabolic process GO:0009100 99 98 0,000 0,43758142 0,4385332 ! anti-apoptosis GO:0006916 100 99 0,000 0,44089854 0,4416174 ! ectoderm development GO:0007398 99 99 0,000 0,44089854 0,44137752 ! response to other organism GO:0051707 101 100 0,000 0,44419659 0,44443774 ! hemopoiesis GO:0030097 104 100 0,000 0,44419659 0,44419659