pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6815-VanDeVijver-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/vantveer-oligo_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! response to UV GO:0009411 29 29 5,000 9,088E-08 1,675E-04 ! response to light stimulus GO:0009416 53 52 5,000 3,373E-06 3,108E-03 ! ER overload response GO:0006983 6 6 2,000 1,004E-05 6,17E-03 ! negative regulation of T cell proliferation GO:0042130 6 6 2,000 1,004E-05 4,627E-03 GO:0070667|negative regulation of mast cell proliferation, ! negative regulation of DNA binding GO:0043392 19 18 3,000 1,107E-05 4,08E-03 ! response to radiation GO:0009314 70 68 5,000 1,641E-05 5,04E-03 ! negative regulation of binding GO:0051100 21 20 3,000 1,731E-05 4,559E-03 ! negative regulation of lymphocyte proliferation GO:0050672 7 7 2,000 1,747E-05 4,025E-03 GO:0032945|negative regulation of mononuclear cell proliferation, GO:0070664|negative regulation of leukocyte proliferation, ! negative regulation of T cell activation GO:0050868 7 7 2,000 1,747E-05 3,578E-03 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 42 42 4,000 2,014E-05 3,712E-03 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 45 44 4,000 2,54E-05 4,256E-03 ! release of cytochrome c from mitochondria GO:0001836 9 8 2,000 2,78E-05 4,269E-03 ! cytoplasmic sequestering of protein GO:0051220 8 8 2,000 2,78E-05 3,941E-03 ! regulation of DNA binding GO:0051101 47 45 4,000 2,84E-05 3,738E-03 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 46 45 4,000 2,84E-05 3,489E-03 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 47 46 4,000 3,167E-05 3,647E-03 ! positive regulation of ligase activity GO:0051351 47 46 4,000 3,167E-05 3,433E-03 ! regulation of ubiquitin-protein ligase activity GO:0051438 49 48 4,000 3,907E-05 4E-03 ! regulation of ligase activity GO:0051340 50 49 4,000 4,324E-05 4,194E-03 ! regulation of intracellular protein transport GO:0033157 25 25 3,000 4,386E-05 4,042E-03 ! induction of apoptosis by intracellular signals GO:0008629 26 26 3,000 5,152E-05 4,522E-03 ! calcium-independent cell-cell adhesion GO:0016338 10 10 2,000 5,888E-05 4,932E-03 ! apoptotic mitochondrial changes GO:0008637 11 10 2,000 5,888E-05 4,718E-03 ! regulation of nucleocytoplasmic transport GO:0046822 27 27 3,000 6,012E-05 4,616E-03 ! protein amino acid autophosphorylation GO:0046777 28 28 3,000 6,971E-05 5,139E-03 ! positive regulation of nucleocytoplasmic transport GO:0046824 11 11 2,000 8,049E-05 5,705E-03 GO:0032388|positive regulation of intracellular transport, ! negative regulation of lymphocyte activation GO:0051250 11 11 2,000 8,049E-05 5,494E-03 ! negative regulation of cell cycle GO:0045786 92 91 5,000 8,655E-05 5,697E-03 ! regulation of binding GO:0051098 60 57 4,000 9,036E-05 5,743E-03 ! regulation of intracellular transport GO:0032386 31 31 3,000 1,052E-04 6,463E-03 ! proteasomal protein catabolic process GO:0010498 62 61 4,000 1,253E-04 7,447E-03 GO:0043161|proteasomal ubiquitin-dependent protein catabolic process, ! response to endoplasmic reticulum stress GO:0034976 13 13 2,000 1,379E-04 7,943E-03 ! negative regulation of Wnt receptor signaling pathway GO:0030178 13 13 2,000 1,379E-04 7,702E-03 ! negative regulation of leukocyte activation GO:0002695 13 13 2,000 1,379E-04 7,475E-03 ! ectoderm development GO:0007398 99 99 5,000 1,384E-04 7,288E-03 ! negative regulation of transcription from RNA polymerase II promoter GO:0000122 103 100 5,000 1,463E-04 7,491E-03 ! positive regulation of epithelial cell proliferation GO:0050679 14 14 2,000 1,745E-04 8,692E-03 ! regulation of transcription factor activity GO:0051090 38 37 3,000 2,13E-04 0,01032876 GO:0090046|regulation of transcription regulator activity, ! lung development GO:0030324 38 37 3,000 2,13E-04 0,01006392 ! regulation of transcription factor import into nucleus GO:0042990 15 15 2,000 2,169E-04 9,993E-03 ! ER-nuclear signaling pathway GO:0006984 15 15 2,000 2,169E-04 9,749E-03 ! negative regulation of transcription factor activity GO:0043433 16 15 2,000 2,169E-04 9,517E-03 GO:0090048|negative regulation of transcription regulator activity, ! negative regulation of cell activation GO:0050866 15 15 2,000 2,169E-04 9,295E-03 ! respiratory tube development GO:0030323 40 39 3,000 2,62E-04 0,01097575 ! respiratory system development GO:0060541 40 39 3,000 2,62E-04 0,01073184 ! positive regulation of cell motion GO:0051272 39 39 3,000 2,62E-04 0,01049854 ! negative regulation of ligase activity GO:0051352 43 42 3,000 3,502E-04 0,01373182 GO:0051444|negative regulation of ubiquitin-protein ligase activity, GO:0051436|negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 18 18 2,000 3,823E-04 0,0146775 ! negative regulation of DNA metabolic process GO:0051053 19 19 2,000 4,513E-04 0,01697555 ! Wnt receptor signaling pathway GO:0016055 46 45 3,000 4,578E-04 0,01687402 ! regulation of protein import into nucleus GO:0042306 21 21 2,000 6,124E-04 0,02212919 ! negative regulation of protein transport GO:0051224 21 21 2,000 6,124E-04 0,02170363 ! positive regulation of MAP kinase activity GO:0043406 50 49 3,000 6,355E-04 0,02209758 ! prostate gland development GO:0030850 5 5 1,000 6,406E-04 0,02186427 ! regulation of long-term neuronal synaptic plasticity GO:0048169 5 5 1,000 6,406E-04 0,02146674 ! mRNA stabilization GO:0048255 5 5 1,000 6,406E-04 0,0210834 GO:0043489|RNA stabilization, ! dopamine receptor signaling pathway GO:0007212 5 5 1,000 6,406E-04 0,02071352 ! regulation of phospholipase A2 activity GO:0032429 5 5 1,000 6,406E-04 0,02035639 ! receptor clustering GO:0043113 5 5 1,000 6,406E-04 0,02001137 ! actin cytoskeleton reorganization GO:0031532 5 5 1,000 6,406E-04 0,01967784 ! postreplication repair GO:0006301 5 5 1,000 6,406E-04 0,01935526 ! T cell lineage commitment GO:0002360 5 5 1,000 6,406E-04 0,01904307 ! peptidyl-lysine modification GO:0018205 5 5 1,000 6,406E-04 0,0187408 ! negative regulation of neuroblast proliferation GO:0007406 5 5 1,000 6,406E-04 0,01844798 ! positive regulation of blood vessel endothelial cell migration GO:0043536 5 5 1,000 6,406E-04 0,01816416 ! regulation of DNA metabolic process GO:0051052 51 50 3,000 6,866E-04 0,01917213 ! maintenance of protein location in cell GO:0032507 23 22 2,000 7,05E-04 0,01939211 ! regulation of Wnt receptor signaling pathway GO:0030111 23 22 2,000 7,05E-04 0,01910693 ! response to hypoxia GO:0001666 53 53 3,000 8,573E-04 0,02289952 ! regulation of protein transport GO:0051223 53 53 3,000 8,573E-04 0,02257239 GO:0070201|regulation of establishment of protein localization, ! T cell differentiation GO:0030217 24 24 2,000 9,159E-04 0,02377516 ! maintenance of protein location GO:0045185 25 24 2,000 9,159E-04 0,02344495 ! glucan metabolic process GO:0044042 25 24 2,000 9,159E-04 0,02312379 GO:0006073|cellular glucan metabolic process, GO:0005977|glycogen metabolic process, ! response to oxygen levels GO:0070482 55 54 3,000 9,204E-04 0,02292191 ! N-terminal protein amino acid modification GO:0031365 6 6 1,000 9,559E-04 0,02349002 GO:0018409|peptide or protein amino-terminal blocking, ! somatic diversification of immune receptors via somatic mutation GO:0002566 6 6 1,000 9,559E-04 0,02318094 GO:0016446|somatic hypermutation of immunoglobulin genes, ! regulation of B cell proliferation GO:0030888 6 6 1,000 9,559E-04 0,02287989 ! cartilage condensation GO:0001502 7 6 1,000 9,559E-04 0,02258656 ! regulation of activated T cell proliferation GO:0046006 6 6 1,000 9,559E-04 0,02230065 ! regulation of positive chemotaxis GO:0050926 6 6 1,000 9,559E-04 0,0220219 GO:0050927|positive regulation of positive chemotaxis, ! cytoplasmic sequestering of transcription factor GO:0042994 6 6 1,000 9,559E-04 0,02175002 ! positive regulation of transcription factor import into nucleus GO:0042993 6 6 1,000 9,559E-04 0,02148478 ! regulation of vascular permeability GO:0043114 6 6 1,000 9,559E-04 0,02122592 ! peptidyl-serine phosphorylation GO:0018105 6 6 1,000 9,559E-04 0,02097323 ! regulation of bone resorption GO:0045124 6 6 1,000 9,559E-04 0,02072649 ! purine base biosynthetic process GO:0009113 6 6 1,000 9,559E-04 0,02048548 ! G1 DNA damage checkpoint GO:0031571 6 6 1,000 9,559E-04 0,02025002 ! regulation of T cell differentiation in the thymus GO:0033081 6 6 1,000 9,559E-04 0,02001991 ! phosphoinositide 3-kinase cascade GO:0014065 6 6 1,000 9,559E-04 0,01979496 ! multicellular organismal aging GO:0010259 6 6 1,000 9,559E-04 0,01957502 ! negative regulation of BMP signaling pathway GO:0030514 6 6 1,000 9,559E-04 0,01935991 ! regulation of RNA splicing GO:0043484 6 6 1,000 9,559E-04 0,01914947 ! localization within membrane GO:0051668 6 6 1,000 9,559E-04 0,01894357 ! regulation of T cell proliferation GO:0042129 25 25 2,000 1,035E-03 0,02028937 ! negative regulation of immune system process GO:0002683 25 25 2,000 1,035E-03 0,0200758 ! regulation of protein localization GO:0032880 58 57 3,000 1,129E-03 0,02167401 ! maintenance of location in cell GO:0051651 27 26 2,000 1,163E-03 0,02209877 ! peptidyl-amino acid modification GO:0018193 61 59 3,000 1,285E-03 0,02417008 ! energy reserve metabolic process GO:0006112 28 27 2,000 1,301E-03 0,02421898 ! learning or memory GO:0007611 28 27 2,000 1,301E-03 0,02397679 ! axis specification GO:0009798 7 7 1,000 1,331E-03 0,02429278 ! response to X-ray GO:0010165 7 7 1,000 1,331E-03 0,02405462 ! regulation of intracellular pH GO:0051453 7 7 1,000 1,331E-03 0,02382108 ! response to gamma radiation GO:0010332 8 7 1,000 1,331E-03 0,02359203 ! regulation of mRNA stability GO:0043488 7 7 1,000 1,331E-03 0,02336734 ! regulation of mast cell proliferation GO:0070666 28 28 2,000 1,449E-03 0,02518851 ! regulation of epithelial cell proliferation GO:0050678 29 29 2,000 1,607E-03 0,02767256 ! regulation of lymphocyte proliferation GO:0050670 29 29 2,000 1,607E-03 0,02741633 GO:0032944|regulation of mononuclear cell proliferation, GO:0070663|regulation of leukocyte proliferation, ! positive regulation of protein transport GO:0051222 29 29 2,000 1,607E-03 0,02716481 ! angiogenesis GO:0001525 65 64 3,000 1,741E-03 0,02917045 ! negative regulation of bone remodeling GO:0046851 8 8 1,000 1,766E-03 0,02931849 ! regulation of neuronal synaptic plasticity GO:0048168 8 8 1,000 1,766E-03 0,02905672 ! negative regulation of transcription factor import into nucleus GO:0042992 8 8 1,000 1,766E-03 0,02879958 ! cell-cell junction assembly GO:0007043 8 8 1,000 1,766E-03 0,02854695 ! positive regulation of endothelial cell migration GO:0010595 8 8 1,000 1,766E-03 0,02829872 ! fructose metabolic process GO:0006000 8 8 1,000 1,766E-03 0,02805476 ! sex determination GO:0007530 8 8 1,000 1,766E-03 0,02781498 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 8 8 1,000 1,766E-03 0,02757926 ! immunoglobulin production during immune response GO:0002381 8 8 1,000 1,766E-03 0,0273475 GO:0002208|somatic diversification of immunoglobulins during immune response, GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! negative regulation of blood coagulation GO:0030195 9 8 1,000 1,766E-03 0,0271196 ! T cell homeostasis GO:0043029 8 8 1,000 1,766E-03 0,02689547 ! peptidyl-serine modification GO:0018209 8 8 1,000 1,766E-03 0,02667502 ! positive regulation of leukocyte migration GO:0002687 8 8 1,000 1,766E-03 0,02645815 ! regulation of RNA stability GO:0043487 8 8 1,000 1,766E-03 0,02624478 ! regulation of MAP kinase activity GO:0043405 67 66 3,000 1,951E-03 0,02876985 ! B cell activation GO:0042113 31 31 2,000 1,954E-03 0,02857762 ! aging GO:0007568 32 31 2,000 1,954E-03 0,0283526 ! regulation of DNA replication GO:0006275 32 31 2,000 1,954E-03 0,0281311 ! maintenance of location GO:0051235 33 32 2,000 2,144E-03 0,03062395 ! regulation of nitric-oxide synthase activity GO:0050999 9 9 1,000 2,258E-03 0,032018 ! positive regulation of endothelial cell proliferation GO:0001938 9 9 1,000 2,258E-03 0,03177359 ! platelet-derived growth factor receptor signaling pathway GO:0048008 9 9 1,000 2,258E-03 0,03153288 ! glutamine metabolic process GO:0006541 9 9 1,000 2,258E-03 0,03129579 ! nucleobase biosynthetic process GO:0046112 9 9 1,000 2,258E-03 0,03106224 ! negative regulation of protein import into nucleus GO:0042308 9 9 1,000 2,258E-03 0,03083215 ! positive regulation of protein import into nucleus GO:0042307 9 9 1,000 2,258E-03 0,03060544 ! regulation of cellular pH GO:0030641 9 9 1,000 2,258E-03 0,03038204 ! histone acetylation GO:0016573 9 9 1,000 2,258E-03 0,03016188 ! DNA fragmentation involved in apoptosis GO:0006309 9 9 1,000 2,258E-03 0,02994489 ! negative regulation of tissue remodeling GO:0034104 9 9 1,000 2,258E-03 0,029731 ! regulation of leukocyte migration GO:0002685 9 9 1,000 2,258E-03 0,02952014 ! purine base metabolic process GO:0006144 9 9 1,000 2,258E-03 0,02931225 ! somatic recombination of immunoglobulin gene segments GO:0016447 9 9 1,000 2,258E-03 0,02910727 ! regulation of blood vessel endothelial cell migration GO:0043535 9 9 1,000 2,258E-03 0,02890514 ! positive regulation of transport GO:0051050 71 70 3,000 2,423E-03 0,03080276 ! negative regulation of signal transduction GO:0009968 71 71 3,000 2,553E-03 0,03222394 ! cellular polysaccharide metabolic process GO:0044264 35 34 2,000 2,556E-03 0,03205164 ! regulation of angiogenesis GO:0045765 35 34 2,000 2,556E-03 0,03183508 ! positive regulation of hydrolase activity GO:0051345 72 72 3,000 2,687E-03 0,03323224 ! regulation of cyclin-dependent protein kinase activity GO:0000079 35 35 2,000 2,78E-03 0,03415851 ! mesoderm development GO:0007498 35 35 2,000 2,78E-03 0,0339323 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 10 10 1,000 2,808E-03 0,0340513 ! negative regulation of nucleocytoplasmic transport GO:0046823 10 10 1,000 2,808E-03 0,03382874 ! induction of apoptosis via death domain receptors GO:0008625 10 10 1,000 2,808E-03 0,03360907 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 10 10 1,000 2,808E-03 0,03339224 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cell structure disassembly during apoptosis GO:0006921 10 10 1,000 2,808E-03 0,03317819 ! neuromuscular junction development GO:0007528 10 10 1,000 2,808E-03 0,03296686 ! mismatch repair GO:0006298 10 10 1,000 2,808E-03 0,03275821 ! synaptic vesicle transport GO:0048489 11 10 1,000 2,808E-03 0,03255218 ! regulation of BMP signaling pathway GO:0030510 10 10 1,000 2,808E-03 0,03234873 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 10 10 1,000 2,808E-03 0,03214781 ! lymphocyte homeostasis GO:0002260 10 10 1,000 2,808E-03 0,03194937 ! positive regulation of neuron apoptosis GO:0043525 10 10 1,000 2,808E-03 0,03175336 ! negative regulation of homeostatic process GO:0032845 10 10 1,000 2,808E-03 0,03155974 ! negative regulation of coagulation GO:0050819 11 10 1,000 2,808E-03 0,03136847 ! protein stabilization GO:0050821 10 10 1,000 2,808E-03 0,0311795 ! positive regulation of cell migration GO:0030335 36 36 2,000 3,015E-03 0,03327879 ! adaptive immune response GO:0002250 37 37 2,000 3,263E-03 0,03579345 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! DNA damage response, signal transduction GO:0042770 37 37 2,000 3,263E-03 0,03558165 ! negative regulation of cell communication GO:0010648 76 76 3,000 3,271E-03 0,0354614 ! G1 phase of mitotic cell cycle GO:0000080 12 11 1,000 3,415E-03 0,03680123 ! phosphatidylinositol metabolic process GO:0046488 11 11 1,000 3,415E-03 0,03658727 ! signal complex assembly GO:0007172 11 11 1,000 3,415E-03 0,03637578 ! protein amino acid acetylation GO:0006473 11 11 1,000 3,415E-03 0,03616672 ! regulation of transmembrane transporter activity GO:0022898 11 11 1,000 3,415E-03 0,03596006 GO:0032412|regulation of ion transmembrane transporter activity, GO:0032409|regulation of transporter activity, ! cellular response to starvation GO:0009267 11 11 1,000 3,415E-03 0,03575574 ! positive regulation of nitric oxide biosynthetic process GO:0045429 11 11 1,000 3,415E-03 0,03555373 ! apoptotic nuclear changes GO:0030262 11 11 1,000 3,415E-03 0,03535399 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 11 11 1,000 3,415E-03 0,03515648 ! G1/S transition checkpoint GO:0031575 12 11 1,000 3,415E-03 0,03496117 ! regulation of monooxygenase activity GO:0032768 11 11 1,000 3,415E-03 0,03476801 ! muscle maintenance GO:0046716 12 11 1,000 3,415E-03 0,03457698 ! somatic diversification of immunoglobulins GO:0016445 11 11 1,000 3,415E-03 0,03438803 ! urogenital system development GO:0001655 38 38 2,000 3,522E-03 0,03527908 ! regulation of cell motion GO:0051270 79 79 3,000 3,762E-03 0,03748089 ! developmental maturation GO:0021700 39 39 2,000 3,794E-03 0,03759168 ! lymphocyte differentiation GO:0030098 39 39 2,000 3,794E-03 0,03739066 ! protein oligomerization GO:0051259 39 39 2,000 3,794E-03 0,03719177 ! DNA catabolic process, endonucleolytic GO:0000737 12 12 1,000 4,076E-03 0,03974753 ! post-Golgi vesicle-mediated transport GO:0006892 12 12 1,000 4,076E-03 0,03953833 ! positive regulation of endocytosis GO:0045807 12 12 1,000 4,076E-03 0,03933133 ! fibroblast growth factor receptor signaling pathway GO:0008543 12 12 1,000 4,076E-03 0,03912647 ! somitogenesis GO:0001756 13 12 1,000 4,076E-03 0,03892375 ! G1 phase GO:0051318 13 12 1,000 4,076E-03 0,03872311 ! cellular monovalent inorganic cation homeostasis GO:0030004 12 12 1,000 4,076E-03 0,03852453 ! tube development GO:0035295 83 81 3,000 4,116E-03 0,03870662 ! lymphocyte activation GO:0046649 82 81 3,000 4,116E-03 0,03851014 ! blood vessel morphogenesis GO:0048514 84 83 3,000 4,492E-03 0,0418155 ! positive regulation of smooth muscle cell proliferation GO:0048661 13 13 1,000 4,792E-03 0,04438161 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 13 13 1,000 4,792E-03 0,0441597 GO:0016444|somatic cell DNA recombination, ! G2/M transition of mitotic cell cycle GO:0000086 13 13 1,000 4,792E-03 0,04394 ! gluconeogenesis GO:0006094 13 13 1,000 4,792E-03 0,04372248 ! vasculogenesis GO:0001570 13 13 1,000 4,792E-03 0,0435071 ! regulation of DNA recombination GO:0000018 13 13 1,000 4,792E-03 0,04329383 ! mitochondrial membrane organization GO:0007006 13 13 1,000 4,792E-03 0,04308264 ! regulation of nitric oxide biosynthetic process GO:0045428 13 13 1,000 4,792E-03 0,0428735 ! negative regulation of DNA replication GO:0008156 13 13 1,000 4,792E-03 0,04266638 ! receptor metabolic process GO:0043112 14 13 1,000 4,792E-03 0,04246125 ! actin filament bundle formation GO:0051017 13 13 1,000 4,792E-03 0,04225809 ! negative regulation of protein catabolic process GO:0042177 13 13 1,000 4,792E-03 0,04205686 ! cell aging GO:0007569 13 13 1,000 4,792E-03 0,04185754 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 13 13 1,000 4,792E-03 0,0416601 ! regulation of endothelial cell migration GO:0010594 13 13 1,000 4,792E-03 0,04146451 ! purine nucleoside monophosphate metabolic process GO:0009126 13 13 1,000 4,792E-03 0,04127075 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! nucleobase metabolic process GO:0009112 13 13 1,000 4,792E-03 0,0410788 ! positive regulation of locomotion GO:0040017 13 13 1,000 4,792E-03 0,04088862 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, GO:0050920|regulation of chemotaxis, ! immunoglobulin production GO:0002377 13 13 1,000 4,792E-03 0,04070019 GO:0002440|production of molecular mediator of immune response, ! negative regulation of intracellular transport GO:0032387 13 13 1,000 4,792E-03 0,04051349 ! cell-cell junction organization GO:0045216 13 13 1,000 4,792E-03 0,0403285 ! activation of JUN kinase activity GO:0007257 13 13 1,000 4,792E-03 0,04014519 ! protein tetramerization GO:0051262 13 13 1,000 4,792E-03 0,03996353 ! regulation of cellular localization GO:0060341 86 85 3,000 4,891E-03 0,04060367 ! reproductive structure development GO:0048608 43 43 2,000 5,007E-03 0,04137985 ! mitochondrion organization GO:0007005 44 43 2,000 5,007E-03 0,04119512 ! positive regulation of protein kinase activity GO:0045860 89 86 3,000 5,099E-03 0,04176547 ! regulation of anatomical structure morphogenesis GO:0022603 90 86 3,000 5,099E-03 0,04158067 ! heart development GO:0007507 90 87 3,000 5,313E-03 0,04313329 ! positive regulation of transferase activity GO:0051347 91 88 3,000 5,532E-03 0,04472032 GO:0033674|positive regulation of kinase activity, ! pyruvate metabolic process GO:0006090 14 14 1,000 5,562E-03 0,04476126 ! protein amino acid acylation GO:0043543 14 14 1,000 5,562E-03 0,04456664 ! regulation of behavior GO:0050795 14 14 1,000 5,562E-03 0,04437371 ! base-excision repair GO:0006284 14 14 1,000 5,562E-03 0,04418245 ! regulation of blood coagulation GO:0030193 15 14 1,000 5,562E-03 0,04399282 ! DNA replication GO:0006260 91 91 3,000 6,228E-03 0,04905211 ! protein import into nucleus, translocation GO:0000060 15 15 1,000 6,384E-03 0,05006727 ! response to starvation GO:0042594 15 15 1,000 6,384E-03 0,04985512 ! response to ionizing radiation GO:0010212 16 15 1,000 6,384E-03 0,04964476 ! leukocyte homeostasis GO:0001776 15 15 1,000 6,384E-03 0,04943617 ! somatic diversification of immune receptors GO:0002200 15 15 1,000 6,384E-03 0,04922932 ! actin filament organization GO:0007015 50 48 2,000 6,819E-03 0,05236507 ! blood vessel development GO:0001568 95 94 3,000 6,98E-03 0,05337533 ! epidermis development GO:0008544 94 94 3,000 6,98E-03 0,05315477 ! leukocyte differentiation GO:0002521 50 49 2,000 7,222E-03 0,05477721 ! ossification GO:0001503 50 49 2,000 7,222E-03 0,05455272 GO:0060348|bone development, ! gland development GO:0048732 51 49 2,000 7,222E-03 0,05433005 ! skeletal muscle tissue development GO:0007519 50 49 2,000 7,222E-03 0,0541092 GO:0060538|skeletal muscle organ development, ! negative regulation of adenylate cyclase activity GO:0007194 16 16 1,000 7,258E-03 0,05415694 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! regulation of synaptic plasticity GO:0048167 16 16 1,000 7,258E-03 0,05393857 ! learning GO:0007612 16 16 1,000 7,258E-03 0,05372195 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 16 16 1,000 7,258E-03 0,05350706 ! segmentation GO:0035282 17 16 1,000 7,258E-03 0,05329389 ! cellular response to nutrient levels GO:0031669 16 16 1,000 7,258E-03 0,0530824 ! regulation of JUN kinase activity GO:0043506 17 16 1,000 7,258E-03 0,05287259 GO:0043507|positive regulation of JUN kinase activity, ! regulation of coagulation GO:0050818 17 16 1,000 7,258E-03 0,05266443 ! regulation of cell growth GO:0001558 97 96 3,000 7,513E-03 0,05429824 ! vasculature development GO:0001944 97 96 3,000 7,513E-03 0,05408614 ! negative regulation of transport GO:0051051 51 50 2,000 7,64E-03 0,05478492 ! chromatin assembly GO:0031497 50 50 2,000 7,64E-03 0,05457258 GO:0006334|nucleosome assembly, ! T cell activation GO:0042110 51 50 2,000 7,64E-03 0,05436187 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 50 50 2,000 7,64E-03 0,05415279 ! protein-DNA complex assembly GO:0065004 51 51 2,000 8,071E-03 0,05699007 ! interphase of mitotic cell cycle GO:0051329 52 51 2,000 8,071E-03 0,05677255 GO:0051325|interphase, ! regulation of fibroblast proliferation GO:0048145 17 17 1,000 8,183E-03 0,05734449 ! regulation of smooth muscle cell proliferation GO:0048660 17 17 1,000 8,183E-03 0,05712728 ! positive regulation of cell adhesion GO:0045785 17 17 1,000 8,183E-03 0,0569117 ! myelination GO:0042552 17 17 1,000 8,183E-03 0,05669775 ! regulation of transmembrane transport GO:0034762 17 17 1,000 8,183E-03 0,0564854 ! cell junction assembly GO:0034329 18 17 1,000 8,183E-03 0,05627463 ! tissue remodeling GO:0048771 17 17 1,000 8,183E-03 0,05606543 ! response to toxin GO:0009636 18 17 1,000 8,183E-03 0,05585778 ! negative regulation of cell development GO:0010721 18 17 1,000 8,183E-03 0,05565166 GO:0050768|negative regulation of neurogenesis, ! regulation of oxidoreductase activity GO:0051341 17 17 1,000 8,183E-03 0,05544706 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 52 52 2,000 8,516E-03 0,05749123 ! cell fate commitment GO:0045165 52 52 2,000 8,516E-03 0,05728141 ! regulation of T cell activation GO:0050863 53 53 2,000 8,976E-03 0,06015276 ! meiosis I GO:0007127 18 18 1,000 9,158E-03 0,06115484 ! epidermal growth factor receptor signaling pathway GO:0007173 18 18 1,000 9,158E-03 0,06093406 ! ribonucleoside monophosphate metabolic process GO:0009161 18 18 1,000 9,158E-03 0,06071488 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! hexose biosynthetic process GO:0019319 18 18 1,000 9,158E-03 0,06049726 ! B cell differentiation GO:0030183 18 18 1,000 9,158E-03 0,0602812 ! cellular response to extracellular stimulus GO:0031668 18 18 1,000 9,158E-03 0,06006668 ! ensheathment of neurons GO:0007272 18 18 1,000 9,158E-03 0,05985367 GO:0008366|axon ensheathment, ! negative regulation of catabolic process GO:0009895 18 18 1,000 9,158E-03 0,05964218 ! negative regulation of multicellular organismal process GO:0051241 55 54 2,000 9,449E-03 0,06132145 ! nucleosome organization GO:0034728 55 55 2,000 9,938E-03 0,06426358 ! DNA damage checkpoint GO:0000077 19 19 1,000 0,01018264 0,06561752 ! regulation of pH GO:0006885 19 19 1,000 0,01018264 0,06538889 ! regulation of endothelial cell proliferation GO:0001936 19 19 1,000 0,01018264 0,06516184 ! peptidyl-tyrosine phosphorylation GO:0018108 20 19 1,000 0,01018264 0,06493637 ! peripheral nervous system development GO:0007422 19 19 1,000 0,01018264 0,06471245 ! regulation of protein stability GO:0031647 19 19 1,000 0,01018264 0,06449007 ! dorsal/ventral pattern formation GO:0009953 19 19 1,000 0,01018264 0,06426921 ! regulation of cell shape GO:0008360 21 19 1,000 0,01018264 0,06404986 ! reproductive developmental process GO:0003006 56 56 2,000 0,0104404 0,06544779 ! nucleus organization GO:0006997 20 20 1,000 0,01125539 0,07031757 ! positive regulation of gene-specific transcription GO:0043193 20 20 1,000 0,01125539 0,07008001 ! peptidyl-tyrosine modification GO:0018212 21 20 1,000 0,01125539 0,06984405 ! monosaccharide biosynthetic process GO:0046364 20 20 1,000 0,01125539 0,06960967 ! regulation of B cell activation GO:0050864 20 20 1,000 0,01125539 0,06937687 ! G1/S transition of mitotic cell cycle GO:0000082 21 21 1,000 0,01237571 0,0760281 ! mammary gland development GO:0030879 23 21 1,000 0,01237571 0,07577551 ! receptor-mediated endocytosis GO:0006898 21 21 1,000 0,01237571 0,0755246 ! DNA integrity checkpoint GO:0031570 21 21 1,000 0,01237571 0,07527534 ! regulation of action potential in neuron GO:0019228 21 21 1,000 0,01237571 0,07502773 ! negative regulation of hydrolase activity GO:0051346 21 21 1,000 0,01237571 0,07478174 ! regulation of protein amino acid phosphorylation GO:0001932 62 61 2,000 0,01317406 0,07934571 ! positive regulation of transcription factor activity GO:0051091 22 22 1,000 0,01354278 0,0813008 GO:0090047|positive regulation of transcription regulator activity, ! cell junction organization GO:0034330 23 22 1,000 0,01354278 0,08103684 ! pigment biosynthetic process GO:0046148 22 22 1,000 0,01354278 0,08077458 ! male sex differentiation GO:0046661 22 22 1,000 0,01354278 0,08051402 ! regulation of lymphocyte activation GO:0051249 62 62 2,000 0,01376526 0,08157354 ! glucose metabolic process GO:0006006 63 63 2,000 0,01437142 0,0848927 ! epithelial cell differentiation GO:0030855 23 23 1,000 0,0147558 0,0868848 ! mitotic cell cycle checkpoint GO:0007093 24 23 1,000 0,0147558 0,0866081 ! induction of apoptosis by extracellular signals GO:0008624 23 23 1,000 0,0147558 0,08633315 ! monovalent inorganic cation homeostasis GO:0055067 23 23 1,000 0,0147558 0,08605995 ! calcium-mediated signaling GO:0019722 23 23 1,000 0,0147558 0,08578846 ! regulation of JNK cascade GO:0046328 25 23 1,000 0,0147558 0,08551869 ! cell projection assembly GO:0030031 25 23 1,000 0,0147558 0,0852506 ! regulation of response to external stimulus GO:0032101 65 64 2,000 0,01499258 0,08634791 ! mitochondrial transport GO:0006839 24 24 1,000 0,01601397 0,09194315 ! regulation of action potential GO:0001508 24 24 1,000 0,01601397 0,09165762 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 26 24 1,000 0,01601397 0,09137385 ! glucose homeostasis GO:0042593 24 24 1,000 0,01601397 0,09109183 GO:0033500|carbohydrate homeostasis, ! androgen receptor signaling pathway GO:0030521 24 24 1,000 0,01601397 0,09081155 ! DNA packaging GO:0006323 66 66 2,000 0,01628011 0,09203756 ! polysaccharide metabolic process GO:0005976 69 66 2,000 0,01628011 0,0917561 ! striated muscle tissue development GO:0014706 69 67 2,000 0,01694655 0,09522101 ! regulation of gene-specific transcription GO:0032583 25 25 1,000 0,01731651 0,09700402 ! cellular component disassembly GO:0022411 26 25 1,000 0,01731651 0,09671007 ! endosome transport GO:0016197 25 25 1,000 0,01731651 0,09641789 ! alcohol biosynthetic process GO:0046165 25 25 1,000 0,01731651 0,09612748 ! positive regulation of DNA binding GO:0043388 26 25 1,000 0,01731651 0,09583881 ! regulation of endocytosis GO:0030100 25 25 1,000 0,01731651 0,09555186 ! chromatin assembly or disassembly GO:0006333 68 68 2,000 0,01762815 0,09698114 ! sensory perception of sound GO:0007605 71 69 2,000 0,01832494 0,10051449 GO:0050954|sensory perception of mechanical stimulus, ! regionalization GO:0003002 70 69 2,000 0,01832494 0,10021623 ! regulation of leukocyte activation GO:0002694 69 69 2,000 0,01832494 0,09991973 ! regulation of mitotic cell cycle GO:0007346 72 69 2,000 0,01832494 0,09962499 ! positive regulation of binding GO:0051099 27 26 1,000 0,01866262 0,1011624 ! glycolysis GO:0006096 26 26 1,000 0,01866262 0,10086574 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 26 26 1,000 0,01866262 0,10057081 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 26 26 1,000 0,01866262 0,1002776 ! regulation of T cell differentiation GO:0045580 26 26 1,000 0,01866262 0,0999861 ! double-strand break repair GO:0006302 27 26 1,000 0,01866262 0,09969628 ! pigment metabolic process GO:0042440 26 26 1,000 0,01866262 0,09940814 ! synapse organization GO:0050808 26 26 1,000 0,01866262 0,09912166 ! wound healing GO:0042060 74 70 2,000 0,01903695 0,10081925 ! muscle tissue development GO:0060537 72 70 2,000 0,01903695 0,10053037 ! regulation of cell migration GO:0030334 71 71 2,000 0,0197642 0,10407261 ! regulation of cell activation GO:0050865 71 71 2,000 0,0197642 0,1037761 ! cAMP-mediated signaling GO:0019933 27 27 1,000 0,02005156 0,10498585 ! activation of caspase activity GO:0006919 27 27 1,000 0,02005156 0,10468844 ! glutamine family amino acid metabolic process GO:0009064 28 27 1,000 0,02005156 0,10439271 ! stress-activated protein kinase signaling pathway GO:0031098 28 28 1,000 0,02148255 0,11152769 GO:0007254|JNK cascade, ! keratinocyte differentiation GO:0030216 28 28 1,000 0,02148255 0,11121441 ! histone modification GO:0016570 28 28 1,000 0,02148255 0,11090289 ! cartilage development GO:0051216 29 28 1,000 0,02148255 0,1105931 ! positive regulation of cell cycle GO:0045787 29 29 1,000 0,02295484 0,11784336 ! phosphoinositide metabolic process GO:0030384 29 29 1,000 0,02295484 0,11751602 ! branching morphogenesis of a tube GO:0048754 29 29 1,000 0,02295484 0,11719049 ! DNA-dependent DNA replication GO:0006261 29 29 1,000 0,02295484 0,11686676 ! covalent chromatin modification GO:0016569 29 29 1,000 0,02295484 0,11654481 ! positive regulation of peptidase activity GO:0010952 30 30 1,000 0,02446769 0,1238845 GO:0043280|positive regulation of caspase activity, ! neuropeptide signaling pathway GO:0007218 30 30 1,000 0,02446769 0,12354509 ! activation of phospholipase C activity GO:0007202 30 30 1,000 0,02446769 0,12320753 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of response to external stimulus GO:0032103 30 30 1,000 0,02446769 0,12287182 ! skeletal system morphogenesis GO:0048705 31 30 1,000 0,02446769 0,12253793 ! vascular process in circulatory system GO:0003018 31 30 1,000 0,02446769 0,12220585 ! immunoglobulin mediated immune response GO:0016064 30 30 1,000 0,02446769 0,12187556 GO:0019724|B cell mediated immunity, ! vesicle organization GO:0016050 30 30 1,000 0,02446769 0,12154706 ! regulation of protein modification process GO:0031399 79 78 2,000 0,02528259 0,12525754 ! positive regulation of protein kinase cascade GO:0010740 79 78 2,000 0,02528259 0,12492173 ! skeletal muscle fiber development GO:0048741 31 31 1,000 0,02602038 0,12822341 ! positive regulation of phospholipase activity GO:0010518 31 31 1,000 0,02602038 0,12788148 ! epidermal cell differentiation GO:0009913 31 31 1,000 0,02602038 0,12754137 ! negative regulation of cell motion GO:0051271 31 31 1,000 0,02602038 0,12720307 ! regulation of locomotion GO:0040012 79 79 2,000 0,02613207 0,12741112 ! negative regulation of cell growth GO:0030308 32 32 1,000 0,02761217 0,13427237 ! muscle fiber development GO:0048747 32 32 1,000 0,02761217 0,13391902 ! glucose catabolic process GO:0006007 32 32 1,000 0,02761217 0,13356752 ! regulation of phospholipase activity GO:0010517 32 32 1,000 0,02761217 0,13321787 ! regulation of vesicle-mediated transport GO:0060627 33 32 1,000 0,02761217 0,13287004 ! cell maturation GO:0048469 32 32 1,000 0,02761217 0,13252403 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 32 32 1,000 0,02761217 0,13217981 ! morphogenesis of a branching structure GO:0001763 32 32 1,000 0,02761217 0,13183738 ! regulation of lymphocyte differentiation GO:0045619 32 32 1,000 0,02761217 0,13149671 ! positive regulation of lipase activity GO:0060193 32 32 1,000 0,02761217 0,1311578 ! negative regulation of cell size GO:0045792 33 33 1,000 0,02924235 0,13854409 ! regulation of cellular response to stress GO:0080135 35 33 1,000 0,02924235 0,13818885 ! regulation of neuron apoptosis GO:0043523 34 33 1,000 0,02924235 0,13783543 ! regulation of synaptic transmission GO:0050804 33 33 1,000 0,02924235 0,13748381 ! regulation of actin filament length GO:0030832 34 34 1,000 0,03091022 0,14495555 ! regulation of bone remodeling GO:0046850 34 34 1,000 0,03091022 0,14458764 ! regulation of protein catabolic process GO:0042176 35 34 1,000 0,03091022 0,1442216 ! nucleoside monophosphate biosynthetic process GO:0009124 34 34 1,000 0,03091022 0,1438574 ! secondary metabolic process GO:0019748 34 34 1,000 0,03091022 0,14349504 ! hexose metabolic process GO:0019318 87 86 2,000 0,0325052 0,15052033 ! regulation of cellular component size GO:0032535 35 35 1,000 0,03261507 0,15065057 ! regulation of cell morphogenesis GO:0022604 38 35 1,000 0,03261507 0,15027394 ! positive regulation of phosphorylation GO:0042327 35 35 1,000 0,03261507 0,1498992 ! regulation of tissue remodeling GO:0034103 35 35 1,000 0,03261507 0,14952631 ! positive regulation of phosphorus metabolic process GO:0010562 36 36 1,000 0,03435622 0,15711791 GO:0045937|positive regulation of phosphate metabolic process, ! integrin-mediated signaling pathway GO:0007229 36 36 1,000 0,03435622 0,15672901 ! regulation of transmission of nerve impulse GO:0051969 36 36 1,000 0,03435622 0,15634202 ! gonad development GO:0008406 36 36 1,000 0,03435622 0,15595695 ! regulation of lipase activity GO:0060191 36 36 1,000 0,03435622 0,15557376 ! coagulation GO:0050817 39 36 1,000 0,03435622 0,15519245 GO:0007596|blood coagulation, ! chemotaxis GO:0006935 90 89 2,000 0,03546394 0,15980451 GO:0042330|taxis, ! regulation of adenylate cyclase activity GO:0045761 37 37 1,000 0,03613299 0,1624222 GO:0031279|regulation of cyclase activity, GO:0051339|regulation of lyase activity, ! meiosis GO:0007126 37 37 1,000 0,03613299 0,16202702 GO:0051327|M phase of meiotic cell cycle, ! negative regulation of protein kinase activity GO:0006469 37 37 1,000 0,03613299 0,16163375 ! response to drug GO:0042493 37 37 1,000 0,03613299 0,16124238 ! lymphocyte mediated immunity GO:0002449 37 37 1,000 0,03613299 0,16085291 ! negative regulation of growth GO:0045926 37 37 1,000 0,03613299 0,16046531 ! negative regulation of kinase activity GO:0033673 38 38 1,000 0,0379447 0,16810599 ! cell-matrix adhesion GO:0007160 39 38 1,000 0,0379447 0,16770285 ! hexose catabolic process GO:0019320 38 38 1,000 0,0379447 0,16730165 ! meiotic cell cycle GO:0051321 38 38 1,000 0,0379447 0,16690236 ! axon guidance GO:0007411 39 38 1,000 0,0379447 0,16650498 ! regulation of neurological system process GO:0031644 38 38 1,000 0,0379447 0,16610948 ! steroid hormone receptor signaling pathway GO:0030518 38 38 1,000 0,0379447 0,16571585 ! regulation of homeostatic process GO:0032844 38 38 1,000 0,0379447 0,16532409 ! energy derivation by oxidation of organic compounds GO:0015980 94 92 2,000 0,03855788 0,16759948 ! regulation of cAMP biosynthetic process GO:0030817 39 39 1,000 0,0397907 0,17255119 ! hemostasis GO:0007599 42 39 1,000 0,0397907 0,17214614 ! activation of MAPK activity GO:0000187 39 39 1,000 0,0397907 0,17174298 ! nucleoside monophosphate metabolic process GO:0009123 39 39 1,000 0,0397907 0,17134172 ! nucleotide-excision repair GO:0006289 40 39 1,000 0,0397907 0,17094232 ! cytokine-mediated signaling pathway GO:0019221 39 39 1,000 0,0397907 0,17054478 ! regulation of MAPKKK cascade GO:0043408 41 39 1,000 0,0397907 0,17014908 ! rRNA transcription GO:0009303 5 5 0,000 0,04005198 0,17086991 ! positive regulation of protein ubiquitination GO:0031398 5 5 0,000 0,04005198 0,17047529 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 5 5 0,000 0,04005198 0,17008249 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 5 5 0,000 0,04005198 0,16969149 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! neuron fate specification GO:0048665 5 5 0,000 0,04005198 0,16930229 ! hemoglobin biosynthetic process GO:0042541 5 5 0,000 0,04005198 0,16891487 ! reproductive cellular process GO:0048610 5 5 0,000 0,04005198 0,16852922 ! positive regulation of glucose metabolic process GO:0010907 5 5 0,000 0,04005198 0,16814533 ! negative regulation of blood pressure GO:0045776 6 5 0,000 0,04005198 0,16776318 ! metencephalon development GO:0022037 5 5 0,000 0,04005198 0,16738276 ! water transport GO:0006833 5 5 0,000 0,04005198 0,16700407 GO:0042044|fluid transport, ! forebrain regionalization GO:0021871 5 5 0,000 0,04005198 0,16662709 ! DNA synthesis during DNA repair GO:0000731 5 5 0,000 0,04005198 0,1662518 ! positive regulation of B cell proliferation GO:0030890 5 5 0,000 0,04005198 0,1658782 ! glycerol metabolic process GO:0006071 5 5 0,000 0,04005198 0,16550628 ! regulation of cellular amine metabolic process GO:0033238 5 5 0,000 0,04005198 0,16513602 GO:0042053|regulation of dopamine metabolic process, GO:0042069|regulation of catecholamine metabolic process, ! meiotic prophase I GO:0007128 5 5 0,000 0,04005198 0,16476741 GO:0051324|prophase, ! cell volume homeostasis GO:0006884 5 5 0,000 0,04005198 0,16440044 ! regulation of epidermal growth factor receptor activity GO:0007176 5 5 0,000 0,04005198 0,16403511 GO:0010469|regulation of receptor activity, ! filopodium assembly GO:0046847 7 5 0,000 0,04005198 0,16367139 GO:0030035|microspike assembly, ! CTP metabolic process GO:0046036 5 5 0,000 0,04005198 0,16330929 GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0006241|CTP biosynthetic process, ! Golgi to endosome transport GO:0006895 5 5 0,000 0,04005198 0,16294878 ! GTP metabolic process GO:0046039 5 5 0,000 0,04005198 0,16258987 ! establishment of tissue polarity GO:0007164 5 5 0,000 0,04005198 0,16223253 ! positive regulation of cell-cell adhesion GO:0022409 5 5 0,000 0,04005198 0,16187675 ! regulation of neurotransmitter secretion GO:0046928 5 5 0,000 0,04005198 0,16152254 GO:0001956|positive regulation of neurotransmitter secretion, ! neurotransmitter uptake GO:0001504 5 5 0,000 0,04005198 0,16116987 ! social behavior GO:0035176 5 5 0,000 0,04005198 0,16081873 ! macrophage chemotaxis GO:0048246 6 5 0,000 0,04005198 0,16046913 ! 2-oxoglutarate metabolic process GO:0006103 5 5 0,000 0,04005198 0,16012104 ! memory GO:0007613 5 5 0,000 0,04005198 0,15977446 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 5 5 0,000 0,04005198 0,15942937 ! membrane hyperpolarization GO:0060081 5 5 0,000 0,04005198 0,15908577 ! response to lipid GO:0033993 5 5 0,000 0,04005198 0,15874365 ! erythrocyte maturation GO:0043249 5 5 0,000 0,04005198 0,158403 ! hippocampus development GO:0021766 6 5 0,000 0,04005198 0,15806381 ! regulation of carbohydrate biosynthetic process GO:0043255 5 5 0,000 0,04005198 0,15772607 ! glucocorticoid metabolic process GO:0008211 5 5 0,000 0,04005198 0,15738976 ! middle ear morphogenesis GO:0042474 5 5 0,000 0,04005198 0,15705489 ! amyloid precursor protein catabolic process GO:0042987 5 5 0,000 0,04005198 0,15672144 ! mechanosensory behavior GO:0007638 5 5 0,000 0,04005198 0,1563894 ! heart looping GO:0001947 5 5 0,000 0,04005198 0,15605877 ! negative regulation of endocytosis GO:0045806 5 5 0,000 0,04005198 0,15572953 ! response to interferon-gamma GO:0034341 5 5 0,000 0,04005198 0,15540168 ! pseudouridine synthesis GO:0001522 5 5 0,000 0,04005198 0,15507521 ! endocrine pancreas development GO:0031018 5 5 0,000 0,04005198 0,1547501 ! pH reduction GO:0045851 5 5 0,000 0,04005198 0,15442636 GO:0051452|intracellular pH reduction, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 5 5 0,000 0,04005198 0,15410396 ! lipopolysaccharide metabolic process GO:0008653 5 5 0,000 0,04005198 0,15378291 ! positive regulation of chemokine biosynthetic process GO:0045080 5 5 0,000 0,04005198 0,1534632 ! sphingoid biosynthetic process GO:0046520 5 5 0,000 0,04005198 0,15314481 GO:0046513|ceramide biosynthetic process, ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 5 5 0,000 0,04005198 0,15282774 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! thymic T cell selection GO:0045061 5 5 0,000 0,04005198 0,15251198 ! insulin-like growth factor receptor signaling pathway GO:0048009 5 5 0,000 0,04005198 0,15219752 ! photoreceptor cell maintenance GO:0045494 5 5 0,000 0,04005198 0,15188436 ! adrenal gland development GO:0030325 5 5 0,000 0,04005198 0,15157248 ! regulation of cardiac muscle hypertrophy GO:0010611 5 5 0,000 0,04005198 0,15126188 GO:0010612|regulation of cardiac muscle adaptation, GO:0014743|regulation of muscle hypertrophy, GO:0043502|regulation of muscle adaptation, ! melanocyte differentiation GO:0030318 5 5 0,000 0,04005198 0,15095255 GO:0050931|pigment cell differentiation, ! ovulation GO:0030728 5 5 0,000 0,04005198 0,15064449 ! astrocyte differentiation GO:0048708 5 5 0,000 0,04005198 0,15033768 ! mitochondrial respiratory chain complex assembly GO:0033108 5 5 0,000 0,04005198 0,15003211 GO:0032981|mitochondrial respiratory chain complex I assembly, GO:0010257|NADH dehydrogenase complex assembly, ! pituitary gland development GO:0021983 5 5 0,000 0,04005198 0,14972779 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 5 5 0,000 0,04005198 0,14942469 GO:0033135|regulation of peptidyl-serine phosphorylation, ! tyrosine metabolic process GO:0006570 5 5 0,000 0,04005198 0,14912283 ! cytoskeletal anchoring at plasma membrane GO:0007016 6 5 0,000 0,04005198 0,14882218 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 5 5 0,000 0,04005198 0,14852273 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, GO:0009164|nucleoside catabolic process, ! microtubule nucleation GO:0007020 5 5 0,000 0,04005198 0,1482245 ! regulation of interleukin-6 biosynthetic process GO:0045408 5 5 0,000 0,04005198 0,14792745 ! regulation of interleukin-8 biosynthetic process GO:0045414 5 5 0,000 0,04005198 0,1476316 ! indolalkylamine metabolic process GO:0006586 5 5 0,000 0,04005198 0,14733692 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! muscle cell migration GO:0014812 5 5 0,000 0,04005198 0,14704342 ! phasic smooth muscle contraction GO:0014821 5 5 0,000 0,04005198 0,14675109 ! central nervous system neuron axonogenesis GO:0021955 6 5 0,000 0,04005198 0,14645992 GO:0021952|central nervous system projection neuron axonogenesis, ! sister chromatid cohesion GO:0007062 5 5 0,000 0,04005198 0,1461699 ! response to ATP GO:0033198 5 5 0,000 0,04005198 0,14588103 ! regulation of type I interferon production GO:0032479 5 5 0,000 0,04005198 0,14559329 ! regulation of appetite GO:0032098 5 5 0,000 0,04005198 0,14530669 GO:0032095|regulation of response to food, ! vesicle fusion GO:0006906 5 5 0,000 0,04005198 0,14502122 ! paraxial mesoderm development GO:0048339 5 5 0,000 0,04005198 0,14473686 ! regulation of the force of heart contraction GO:0002026 5 5 0,000 0,04005198 0,14445362 ! maintenance of protein location in nucleus GO:0051457 5 5 0,000 0,04005198 0,14417148 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,04005198 0,14389045 ! neurotransmitter biosynthetic process GO:0042136 6 5 0,000 0,04005198 0,1436105 ! fear response GO:0042596 5 5 0,000 0,04005198 0,14333165 ! lens development in camera-type eye GO:0002088 5 5 0,000 0,04005198 0,14305387 ! retinol metabolic process GO:0042572 5 5 0,000 0,04005198 0,14277717 ! corticosteroid receptor signaling pathway GO:0031958 5 5 0,000 0,04005198 0,14250154 GO:0042921|glucocorticoid receptor signaling pathway, ! temperature homeostasis GO:0001659 5 5 0,000 0,04005198 0,14222697 ! positive regulation of exocytosis GO:0045921 6 5 0,000 0,04005198 0,14195346 ! parturition GO:0007567 5 5 0,000 0,04005198 0,141681 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,04005198 0,14140958 ! regulation of vascular endothelial growth factor production GO:0010574 5 5 0,000 0,04005198 0,1411392 ! Schwann cell differentiation GO:0014037 5 5 0,000 0,04005198 0,14086985 ! acyl-CoA metabolic process GO:0006637 5 5 0,000 0,04005198 0,14060152 ! wound healing, spreading of epidermal cells GO:0035313 5 5 0,000 0,04005198 0,14033422 ! protein heterooligomerization GO:0051291 5 5 0,000 0,04005198 0,14006793 ! regulation of gliogenesis GO:0014013 5 5 0,000 0,04005198 0,13980265 GO:0045685|regulation of glial cell differentiation, ! positive regulation of peptide secretion GO:0002793 5 5 0,000 0,04005198 0,13953837 ! response to UV-B GO:0010224 5 5 0,000 0,04005198 0,13927509 ! oligodendrocyte development GO:0014003 5 5 0,000 0,04005198 0,1390128 ! hyaluronan metabolic process GO:0030212 5 5 0,000 0,04005198 0,1387515 ! activated T cell proliferation GO:0050798 5 5 0,000 0,04005198 0,13849118 ! interaction with symbiont GO:0051702 5 5 0,000 0,04005198 0,13823183 ! cellular extravasation GO:0045123 5 5 0,000 0,04005198 0,13797346 ! positive regulation of axonogenesis GO:0050772 5 5 0,000 0,04005198 0,13771604 ! peptidyl-asparagine modification GO:0018196 5 5 0,000 0,04005198 0,13745959 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! positive regulation of phagocytosis GO:0050766 5 5 0,000 0,04005198 0,13720409 ! regulation of insulin receptor signaling pathway GO:0046626 5 5 0,000 0,04005198 0,13694953 ! antigen processing and presentation of exogenous antigen GO:0019884 5 5 0,000 0,04005198 0,13669592 ! enucleate erythrocyte differentiation GO:0043353 6 5 0,000 0,04005198 0,13644325 ! response to amine stimulus GO:0014075 5 5 0,000 0,04005198 0,13619151 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 5 5 0,000 0,04005198 0,1359407 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 5 5 0,000 0,04005198 0,13569081 ! synaptic vesicle exocytosis GO:0016079 6 5 0,000 0,04005198 0,13544183 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 5 5 0,000 0,04005198 0,13519377 ! glycosylceramide metabolic process GO:0006677 5 5 0,000 0,04005198 0,13494662 ! neuron recognition GO:0008038 5 5 0,000 0,04005198 0,13470036 ! negative regulation of focal adhesion formation GO:0051895 6 5 0,000 0,04005198 0,13445501 ! decidualization GO:0046697 5 5 0,000 0,04005198 0,13421054 ! hair follicle maturation GO:0048820 5 5 0,000 0,04005198 0,13396697 ! phosphatidylinositol biosynthetic process GO:0006661 5 5 0,000 0,04005198 0,13372427 ! regulation of mitochondrial membrane potential GO:0051881 5 5 0,000 0,04005198 0,13348246 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 0,04005198 0,13324151 GO:0009155|purine deoxyribonucleotide catabolic process, ! regulation of interleukin-12 production GO:0032655 5 5 0,000 0,04005198 0,13300144 ! positive regulation of interleukin-6 production GO:0032755 5 5 0,000 0,04005198 0,13276223 ! positive regulation of monooxygenase activity GO:0032770 5 5 0,000 0,04005198 0,13252388 ! spinal cord motor neuron differentiation GO:0021522 5 5 0,000 0,04005198 0,13228638 GO:0021517|ventral spinal cord development, ! cellular pigmentation GO:0033059 5 5 0,000 0,04005198 0,13204973 ! histone methylation GO:0016571 5 5 0,000 0,04005198 0,13181393 ! DNA methylation GO:0006306 5 5 0,000 0,04005198 0,13157896 GO:0006305|DNA alkylation, ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,04005198 0,13134484 ! positive regulation of immunoglobulin mediated immune response GO:0002891 5 5 0,000 0,04005198 0,13111154 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of interferon-gamma production GO:0032729 5 5 0,000 0,04005198 0,13087908 ! negative regulation of tumor necrosis factor production GO:0032720 5 5 0,000 0,04005198 0,13064743 ! intracellular cholesterol transport GO:0032367 5 5 0,000 0,04005198 0,13041661 GO:0032366|intracellular sterol transport, ! regulation of mast cell activation GO:0033003 5 5 0,000 0,04005198 0,13018659 ! morphogenesis of a polarized epithelium GO:0001738 5 5 0,000 0,04005198 0,12995739 ! regulation of hormone metabolic process GO:0032350 5 5 0,000 0,04005198 0,129729 ! regulation of transcription from RNA polymerase III promoter GO:0006359 5 5 0,000 0,04005198 0,1295014 ! regulation of inflammatory response to antigenic stimulus GO:0002861 5 5 0,000 0,04005198 0,1292746 ! sterol catabolic process GO:0016127 5 5 0,000 0,04005198 0,1290486 GO:0006707|cholesterol catabolic process, ! negative regulation of oxidoreductase activity GO:0051354 5 5 0,000 0,04005198 0,12882338 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 5 5 0,000 0,04005198 0,12859895 ! detection of biotic stimulus GO:0009595 5 5 0,000 0,04005198 0,1283753 ! regulation of immune response to tumor cell GO:0002837 5 5 0,000 0,04005198 0,12815243 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 5 5 0,000 0,04005198 0,12793033 ! zymogen activation GO:0031638 5 5 0,000 0,04005198 0,127709 ! positive regulation of interleukin-1 beta secretion GO:0050718 5 5 0,000 0,04005198 0,12748843 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 5 5 0,000 0,04005198 0,12726862 GO:0002820|negative regulation of adaptive immune response, ! cellular response to nutrient GO:0031670 5 5 0,000 0,04005198 0,12704957 ! peptidyl-histidine modification GO:0018202 5 5 0,000 0,04005198 0,12683127 ! nucleosome positioning GO:0016584 5 5 0,000 0,04005198 0,12661372 ! regulation of isotype switching GO:0045191 5 5 0,000 0,04005198 0,12639692 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 5 5 0,000 0,04005198 0,12618085 ! negative regulation of neurological system process GO:0031645 5 5 0,000 0,04005198 0,12596553 ! regulation of myoblast differentiation GO:0045661 5 5 0,000 0,04005198 0,12575094 ! glutathione biosynthetic process GO:0006750 5 5 0,000 0,04005198 0,12553707 ! NADPH regeneration GO:0006740 5 5 0,000 0,04005198 0,12532394 GO:0006098|pentose-phosphate shunt, ! positive regulation of erythrocyte differentiation GO:0045648 5 5 0,000 0,04005198 0,12511152 ! positive regulation of epidermis development GO:0045684 5 5 0,000 0,04005198 0,12489983 ! positive regulation of leukocyte chemotaxis GO:0002690 5 5 0,000 0,04005198 0,12468885 GO:0002688|regulation of leukocyte chemotaxis, ! musculoskeletal movement GO:0050881 5 5 0,000 0,04005198 0,12447858 GO:0050879|multicellular organismal movement, ! neuromuscular process controlling posture GO:0050884 5 5 0,000 0,04005198 0,12426902 ! sarcomere organization GO:0045214 5 5 0,000 0,04005198 0,12406017 ! regulation of epidermal cell differentiation GO:0045604 5 5 0,000 0,04005198 0,12385201 ! activation of NF-kappaB-inducing kinase activity GO:0007250 5 5 0,000 0,04005198 0,12364455 ! negative regulation of glucose transport GO:0010829 5 5 0,000 0,04005198 0,12343779 GO:0046325|negative regulation of glucose import, ! positive regulation of T-helper cell differentiation GO:0045624 5 5 0,000 0,04005198 0,12323172 GO:0045622|regulation of T-helper cell differentiation, ! oocyte differentiation GO:0009994 5 5 0,000 0,04005198 0,12302633 GO:0048599|oocyte development, ! dopamine biosynthetic process GO:0042416 5 5 0,000 0,04005198 0,12282163 ! regulation of protein homodimerization activity GO:0043496 6 5 0,000 0,04005198 0,12261761 ! spleen development GO:0048536 5 5 0,000 0,04005198 0,12241426 ! male genitalia development GO:0030539 5 5 0,000 0,04005198 0,12221159 ! nicotinamide nucleotide biosynthetic process GO:0019359 5 5 0,000 0,04005198 0,12200959 ! quaternary ammonium group transport GO:0015697 5 5 0,000 0,04005198 0,12180825 ! thyroid hormone metabolic process GO:0042403 5 5 0,000 0,04005198 0,12160758 ! leukocyte mediated cytotoxicity GO:0001909 5 5 0,000 0,04005198 0,12140756 ! positive regulation of viral reproduction GO:0048524 5 5 0,000 0,04005198 0,12120821 ! removal of superoxide radicals GO:0019430 6 5 0,000 0,04005198 0,12100951 ! myeloid cell homeostasis GO:0002262 5 5 0,000 0,04005198 0,12081146 ! regulation of fatty acid oxidation GO:0046320 5 5 0,000 0,04005198 0,12061405 ! regulation of Rac protein signal transduction GO:0035020 5 5 0,000 0,04005198 0,12041729 ! ATP catabolic process GO:0006200 5 5 0,000 0,04005198 0,12022117 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,04005198 0,12002569 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 5 5 0,000 0,04005198 0,11983084 ! blastocyst formation GO:0001825 5 5 0,000 0,04005198 0,11963663 ! regulation of fibrinolysis GO:0051917 5 5 0,000 0,04005198 0,11944304 ! embryonic gut development GO:0048566 5 5 0,000 0,04005198 0,11925008 ! negative regulation of organic acid transport GO:0032891 5 5 0,000 0,04005198 0,11905774 ! pyrimidine base metabolic process GO:0006206 5 5 0,000 0,04005198 0,11886602 ! activation of innate immune response GO:0002218 5 5 0,000 0,04005198 0,11867492 GO:0002758|innate immune response-activating signal transduction, ! catecholamine transport GO:0051937 5 5 0,000 0,04005198 0,11848443 ! negative regulation of blood vessel endothelial cell migration GO:0043537 5 5 0,000 0,04005198 0,11829455 ! regulation of NF-kappaB import into nucleus GO:0042345 5 5 0,000 0,04005198 0,11810528 ! muscle adaptation GO:0043500 5 5 0,000 0,04005198 0,11791661 ! positive regulation of actin filament bundle formation GO:0032233 5 5 0,000 0,04005198 0,11772855 ! embryonic heart tube development GO:0035050 5 5 0,000 0,04005198 0,11754108 ! cardiac cell differentiation GO:0035051 6 5 0,000 0,04005198 0,11735421 ! positive regulation of homeostatic process GO:0032846 5 5 0,000 0,04005198 0,11716794 ! defense response to fungus GO:0050832 5 5 0,000 0,04005198 0,11698225 ! lysogeny GO:0030069 5 5 0,000 0,04005198 0,11679715 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 5 5 0,000 0,04005198 0,11661264 ! B cell receptor signaling pathway GO:0050853 5 5 0,000 0,04005198 0,11642871 ! positive regulation of smooth muscle contraction GO:0045987 5 5 0,000 0,04005198 0,11624535 ! response to nicotine GO:0035094 5 5 0,000 0,04005198 0,11606258 ! establishment of cell polarity GO:0030010 5 5 0,000 0,04005198 0,11588038 ! mitochondrion localization GO:0051646 5 5 0,000 0,04005198 0,11569874 ! nucleus localization GO:0051647 5 5 0,000 0,04005198 0,11551768 ! regulation of synapse structure and activity GO:0050803 5 5 0,000 0,04005198 0,11533719 ! regulation of response to stress GO:0080134 97 94 2,000 0,04069508 0,11700629 ! pattern specification process GO:0007389 96 94 2,000 0,04069508 0,11682404 ! regulation of cAMP metabolic process GO:0030814 40 40 1,000 0,04167031 0,11943762 ! DNA catabolic process GO:0006308 41 40 1,000 0,04167031 0,11925215 ! negative regulation of transferase activity GO:0051348 40 40 1,000 0,04167031 0,11906727 ! intracellular receptor-mediated signaling pathway GO:0030522 40 40 1,000 0,04167031 0,11888295 ! regulation of nucleotide biosynthetic process GO:0030808 41 41 1,000 0,04358291 0,12414729 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! cell cycle checkpoint GO:0000075 42 41 1,000 0,04358291 0,1239557 ! regulation of caspase activity GO:0043281 41 41 1,000 0,04358291 0,12376471 ! leukocyte mediated immunity GO:0002443 41 41 1,000 0,04358291 0,1235743 ! monosaccharide catabolic process GO:0046365 41 41 1,000 0,04358291 0,12338448 ! endocytosis GO:0006897 99 98 2,000 0,04514672 0,12761564 GO:0010324|membrane invagination, ! posttranscriptional regulation of gene expression GO:0010608 98 98 2,000 0,04514672 0,12742021 ! regulation of cyclic nucleotide metabolic process GO:0030799 42 42 1,000 0,04552783 0,12829938 ! regulation of endopeptidase activity GO:0052548 42 42 1,000 0,04552783 0,1281035 ! cell-substrate adhesion GO:0031589 43 42 1,000 0,04552783 0,12790823 ! development of primary sexual characteristics GO:0045137 42 42 1,000 0,04552783 0,12771354 ! muscle organ development GO:0007517 102 100 2,000 0,0474603 0,13293211 ! hemopoiesis GO:0030097 104 100 2,000 0,0474603 0,13273039 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 43 43 1,000 0,04750446 0,13265262 ! alcohol catabolic process GO:0046164 43 43 1,000 0,04750446 0,13245193 ! homeostasis of number of cells GO:0048872 44 43 1,000 0,04750446 0,13225185 ! regulation of nucleotide metabolic process GO:0006140 43 43 1,000 0,04750446 0,13205238 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 6 6 0,000 0,04787119 0,1328714 ! axon extension GO:0048675 7 6 0,000 0,04787119 0,13267159 ! oligosaccharide biosynthetic process GO:0009312 6 6 0,000 0,04787119 0,13247239 ! tRNA modification GO:0006400 6 6 0,000 0,04787119 0,13227378 ! 'de novo' posttranslational protein folding GO:0051084 6 6 0,000 0,04787119 0,13207576 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 6 6 0,000 0,04787119 0,13187834 ! negative regulation of cellular catabolic process GO:0031330 6 6 0,000 0,04787119 0,13168151 ! virus-host interaction GO:0019048 6 6 0,000 0,04787119 0,13148526 ! regulation of S phase GO:0033261 6 6 0,000 0,04787119 0,1312896 ! myotube differentiation GO:0014902 6 6 0,000 0,04787119 0,13109452 ! bone remodeling GO:0046849 6 6 0,000 0,04787119 0,13090001 ! N-glycan processing GO:0006491 6 6 0,000 0,04787119 0,13070609 ! regulation of lipid kinase activity GO:0043550 6 6 0,000 0,04787119 0,13051273 ! glycosaminoglycan catabolic process GO:0006027 6 6 0,000 0,04787119 0,13031995 ! negative regulation of JAK-STAT cascade GO:0046426 6 6 0,000 0,04787119 0,13012774 ! retina development in camera-type eye GO:0060041 6 6 0,000 0,04787119 0,1299361 ! RNA methylation GO:0001510 6 6 0,000 0,04787119 0,12974501 ! succinate metabolic process GO:0006105 7 6 0,000 0,04787119 0,12955449 ! artery development GO:0060840 6 6 0,000 0,04787119 0,12936453 GO:0048844|artery morphogenesis, ! positive regulation of neurotransmitter transport GO:0051590 6 6 0,000 0,04787119 0,12917512 ! bile acid metabolic process GO:0008206 6 6 0,000 0,04787119 0,12898627 ! androgen metabolic process GO:0008209 6 6 0,000 0,04787119 0,12879797 ! estrogen metabolic process GO:0008210 6 6 0,000 0,04787119 0,12861022 ! limbic system development GO:0021761 7 6 0,000 0,04787119 0,12842301 ! positive regulation of heart contraction GO:0045823 6 6 0,000 0,04787119 0,12823635 ! positive regulation of gene expression, epigenetic GO:0045815 6 6 0,000 0,04787119 0,12805023 ! pathogenesis GO:0009405 6 6 0,000 0,04787119 0,12786465 ! negative regulation of protein amino acid phosphorylation GO:0001933 6 6 0,000 0,04787119 0,12767961 ! positive regulation of cell growth GO:0030307 6 6 0,000 0,04787119 0,1274951 ! ribonucleoside triphosphate catabolic process GO:0009203 6 6 0,000 0,04787119 0,12731112 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! regulation of chemokine biosynthetic process GO:0045073 6 6 0,000 0,04787119 0,12712768 ! nerve growth factor receptor signaling pathway GO:0048011 6 6 0,000 0,04787119 0,12694476 ! inositol phosphate-mediated signaling GO:0048016 6 6 0,000 0,04787119 0,12676237 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 6 6 0,000 0,04787119 0,1265805 ! arginine metabolic process GO:0006525 6 6 0,000 0,04787119 0,12639915 GO:0006527|arginine catabolic process, ! regulation of catecholamine secretion GO:0050433 6 6 0,000 0,04787119 0,12621832 ! oligodendrocyte differentiation GO:0048709 6 6 0,000 0,04787119 0,12603801 ! glutamate catabolic process GO:0006538 7 6 0,000 0,04787119 0,12585821 ! telomere maintenance via telomerase GO:0007004 6 6 0,000 0,04787119 0,12567893 GO:0010833|telomere maintenance via telomere lengthening, ! L-phenylalanine metabolic process GO:0006558 6 6 0,000 0,04787119 0,12550015 GO:0006559|L-phenylalanine catabolic process, ! glucan biosynthetic process GO:0009250 6 6 0,000 0,04787119 0,12532189 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 6 6 0,000 0,04787119 0,12514413 ! V(D)J recombination GO:0033151 6 6 0,000 0,04787119 0,12496687 ! focal adhesion formation GO:0048041 7 6 0,000 0,04787119 0,12479011 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 0,04787119 0,12461385 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 6 6 0,000 0,04787119 0,12443809 ! negative regulation of endothelial cell migration GO:0010596 6 6 0,000 0,04787119 0,12426283 ! regulation of heart rate GO:0002027 6 6 0,000 0,04787119 0,12408806 ! lipid digestion GO:0044241 6 6 0,000 0,04787119 0,12391378 ! asymmetric protein localization GO:0008105 6 6 0,000 0,04787119 0,12373998 ! retrograde transport, endosome to Golgi GO:0042147 6 6 0,000 0,04787119 0,12356668 ! phagocytosis, engulfment GO:0006911 6 6 0,000 0,04787119 0,12339386 ! Rac protein signal transduction GO:0016601 6 6 0,000 0,04787119 0,12322152 ! regulation of calcium ion transport into cytosol GO:0010522 6 6 0,000 0,04787119 0,12304966 ! ruffle organization GO:0031529 6 6 0,000 0,04787119 0,12287828 ! preassembly of GPI anchor in ER membrane GO:0016254 6 6 0,000 0,04787119 0,12270738 ! retinoic acid metabolic process GO:0042573 6 6 0,000 0,04787119 0,12253696 ! neutral amino acid transport GO:0015804 6 6 0,000 0,04787119 0,122367 ! L-amino acid transport GO:0015807 6 6 0,000 0,04787119 0,12219752 ! bone mineralization GO:0030282 6 6 0,000 0,04787119 0,1220285 GO:0031214|biomineral formation, ! rRNA modification GO:0000154 6 6 0,000 0,04787119 0,12185996 ! negative regulation of ossification GO:0030279 6 6 0,000 0,04787119 0,12169187 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 6 6 0,000 0,04787119 0,12152425 GO:0002717|positive regulation of natural killer cell mediated immunity, GO:0002715|regulation of natural killer cell mediated immunity, GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 7 6 0,000 0,04787119 0,1213571 ! negative regulation of axonogenesis GO:0050771 7 6 0,000 0,04787119 0,1211904 ! regulation of phagocytosis GO:0050764 6 6 0,000 0,04787119 0,12102415 ! regulation of organ growth GO:0046620 6 6 0,000 0,04787119 0,12085837 ! regulation of circadian rhythm GO:0042752 6 6 0,000 0,04787119 0,12069304 ! positive regulation of T cell mediated immunity GO:0002711 6 6 0,000 0,04787119 0,12052815 ! response to dsRNA GO:0043331 6 6 0,000 0,04787119 0,12036372 ! DNA unwinding during replication GO:0006268 6 6 0,000 0,04787119 0,12019974 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 6 6 0,000 0,04787119 0,1200362 GO:0009147|pyrimidine nucleoside triphosphate metabolic process, ! genitalia development GO:0048806 6 6 0,000 0,04787119 0,11987311 ! sphingomyelin metabolic process GO:0006684 6 6 0,000 0,04787119 0,11971046 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 6 6 0,000 0,04787119 0,11954825 ! positive regulation of B cell differentiation GO:0045579 6 6 0,000 0,04787119 0,11938648 ! regulation of focal adhesion formation GO:0051893 7 6 0,000 0,04787119 0,11922515 ! respiratory chain complex IV assembly GO:0008535 6 6 0,000 0,04787119 0,11906425 ! erythrocyte development GO:0048821 6 6 0,000 0,04787119 0,11890379 ! renal water homeostasis GO:0003091 6 6 0,000 0,04787119 0,11874375 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 6 6 0,000 0,04787119 0,11858415 GO:0043372|positive regulation of CD4-positive, alpha beta T cell differentiation, ! ribosomal large subunit biogenesis GO:0042273 6 6 0,000 0,04787119 0,11842498 ! regulation of Rho GTPase activity GO:0032319 6 6 0,000 0,04787119 0,11826623 ! ribosome assembly GO:0042255 6 6 0,000 0,04787119 0,11810791 ! positive regulation of Ras GTPase activity GO:0032320 6 6 0,000 0,04787119 0,11795001 ! diencephalon development GO:0021536 6 6 0,000 0,04787119 0,11779253 ! fucose catabolic process GO:0019317 6 6 0,000 0,04787119 0,11763548 GO:0042355|L-fucose catabolic process, ! nitric oxide metabolic process GO:0046209 6 6 0,000 0,04787119 0,11747884 GO:0006809|nitric oxide biosynthetic process, ! protein sumoylation GO:0016925 6 6 0,000 0,04787119 0,11732262 ! regulation of lipid transport GO:0032368 6 6 0,000 0,04787119 0,11716681 ! regulation of cell division GO:0051302 6 6 0,000 0,04787119 0,11701142 ! positive regulation of interleukin-1 secretion GO:0050716 6 6 0,000 0,04787119 0,11685644 ! cellular metabolic compound salvage GO:0043094 6 6 0,000 0,04787119 0,11670186 ! regulation of T-helper 2 type immune response GO:0002828 6 6 0,000 0,04787119 0,1165477 ! salivary gland morphogenesis GO:0007435 6 6 0,000 0,04787119 0,11639394 ! neuroblast proliferation GO:0007405 6 6 0,000 0,04787119 0,11624059 ! regulation of interleukin-1 beta secretion GO:0050706 6 6 0,000 0,04787119 0,11608764 ! nitric oxide mediated signal transduction GO:0007263 6 6 0,000 0,04787119 0,1159351 ! regulation of glucose transport GO:0010827 6 6 0,000 0,04787119 0,11578295 GO:0046324|regulation of glucose import, ! intestinal absorption GO:0050892 6 6 0,000 0,04787119 0,1156312 ! methionine biosynthetic process GO:0009086 6 6 0,000 0,04787119 0,11547985 ! glutamine family amino acid biosynthetic process GO:0009084 6 6 0,000 0,04787119 0,1153289 ! serine family amino acid biosynthetic process GO:0009070 6 6 0,000 0,04787119 0,11517834 ! thymus development GO:0048538 6 6 0,000 0,04787119 0,11502817 ! lymph node development GO:0048535 6 6 0,000 0,04787119 0,1148784 ! organic cation transport GO:0015695 6 6 0,000 0,04787119 0,11472901 ! regulation of cellular carbohydrate catabolic process GO:0043471 6 6 0,000 0,04787119 0,11458001 GO:0043470|regulation of carbohydrate catabolic process, GO:0006110|regulation of glycolysis, ! positive regulation of JNK cascade GO:0046330 7 6 0,000 0,04787119 0,1144314 ! sperm-egg recognition GO:0035036 7 6 0,000 0,04787119 0,11428317 GO:0007339|binding of sperm to zona pellucida, ! germ cell migration GO:0008354 6 6 0,000 0,04787119 0,11413533 ! establishment or maintenance of apical/basal cell polarity GO:0035088 6 6 0,000 0,04787119 0,11398787 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 6 6 0,000 0,04787119 0,11384079 ! alditol metabolic process GO:0019400 6 6 0,000 0,04787119 0,11369408 ! regulation of synaptic transmission, GABAergic GO:0032228 6 6 0,000 0,04787119 0,11354776 ! regulation of amino acid transport GO:0051955 6 6 0,000 0,04787119 0,11340181 ! maternal placenta development GO:0001893 6 6 0,000 0,04787119 0,11325624 ! regulation of embryonic development GO:0045995 6 6 0,000 0,04787119 0,11311104 ! negative regulation of immune effector process GO:0002698 6 6 0,000 0,04787119 0,11296621 ! protein import into nucleus GO:0006606 44 44 1,000 0,04951217 0,11668918 ! homophilic cell adhesion GO:0007156 45 45 1,000 0,05155035 0,12133753 ! regulation of actin cytoskeleton organization GO:0032956 46 45 1,000 0,05155035 0,12118277 ! phosphoinositide-mediated signaling GO:0048015 45 45 1,000 0,05155035 0,12102839 ! nuclear import GO:0051170 45 45 1,000 0,05155035 0,12087441 ! regulation of actin filament-based process GO:0032970 47 46 1,000 0,05361837 0,12556374 ! cyclic-nucleotide-mediated signaling GO:0019935 46 46 1,000 0,05361837 0,12540439 ! tube morphogenesis GO:0035239 47 46 1,000 0,05361837 0,12524545 ! regulation of peptidase activity GO:0052547 46 46 1,000 0,05361837 0,12508691 ! regulation of membrane potential GO:0042391 46 46 1,000 0,05361837 0,12492878 ! respiratory burst GO:0045730 7 7 0,000 0,05562784 0,12944711 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 7 7 0,000 0,05562784 0,12928388 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 7 7 0,000 0,05562784 0,12912105 ! negative regulation of cell projection organization GO:0031345 8 7 0,000 0,05562784 0,12895864 ! positive regulation of blood pressure GO:0045777 7 7 0,000 0,05562784 0,12879663 ! positive regulation of cellular catabolic process GO:0031331 7 7 0,000 0,05562784 0,12863502 ! pteridine and derivative biosynthetic process GO:0042559 7 7 0,000 0,05562784 0,12847383 ! regulation of chemokine production GO:0032642 7 7 0,000 0,05562784 0,12831303 ! double-strand break repair via homologous recombination GO:0000724 7 7 0,000 0,05562784 0,12815264 GO:0000725|recombinational repair, ! positive regulation of GTPase activity GO:0043547 7 7 0,000 0,05562784 0,12799265 ! SMAD protein nuclear translocation GO:0007184 7 7 0,000 0,05562784 0,12783306 ! cellular protein complex disassembly GO:0043624 8 7 0,000 0,05562784 0,12767387 GO:0043241|protein complex disassembly, ! hair follicle morphogenesis GO:0031069 7 7 0,000 0,05562784 0,12751507 ! gene silencing by RNA GO:0031047 7 7 0,000 0,05562784 0,12735666 ! regulation of receptor-mediated endocytosis GO:0048259 7 7 0,000 0,05562784 0,12719865 ! oxaloacetate metabolic process GO:0006107 7 7 0,000 0,05562784 0,12704103 ! regulation of neurotransmitter transport GO:0051588 7 7 0,000 0,05562784 0,12688381 ! keratinocyte proliferation GO:0043616 7 7 0,000 0,05562784 0,12672697 ! negative regulation of muscle cell differentiation GO:0051148 7 7 0,000 0,05562784 0,12657051 ! visual behavior GO:0007632 7 7 0,000 0,05562784 0,12641444 GO:0008542|visual learning, ! startle response GO:0001964 7 7 0,000 0,05562784 0,12625876 ! amyloid precursor protein metabolic process GO:0042982 7 7 0,000 0,05562784 0,12610346 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 8 7 0,000 0,05562784 0,12594854 ! positive regulation of lipid metabolic process GO:0045834 7 7 0,000 0,05562784 0,12579401 ! negative regulation of lipid metabolic process GO:0045833 7 7 0,000 0,05562784 0,12563985 ! regulation of interferon-gamma biosynthetic process GO:0045072 7 7 0,000 0,05562784 0,12548606 ! endothelial cell differentiation GO:0045446 7 7 0,000 0,05562784 0,12533266 ! negative regulation of striated muscle development GO:0045843 7 7 0,000 0,05562784 0,12517963 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 7 7 0,000 0,05562784 0,12502697 ! digestive system development GO:0055123 7 7 0,000 0,05562784 0,12487468 GO:0048546|digestive tract morphogenesis, GO:0048547|gut morphogenesis, ! hemoglobin metabolic process GO:0020027 7 7 0,000 0,05562784 0,12472277 ! regulation of exit from mitosis GO:0007096 7 7 0,000 0,05562784 0,12457122 ! protein targeting to ER GO:0045047 8 7 0,000 0,05562784 0,12442004 ! cell differentiation in spinal cord GO:0021515 7 7 0,000 0,05562784 0,12426923 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 7 7 0,000 0,05562784 0,12411878 ! endoderm development GO:0007492 7 7 0,000 0,05562784 0,1239687 ! regulation of defense response to virus GO:0050688 7 7 0,000 0,05562784 0,12381898 ! glycolipid biosynthetic process GO:0009247 7 7 0,000 0,05562784 0,12366962 GO:0006688|glycosphingolipid biosynthetic process, ! regulation of mRNA processing GO:0050684 7 7 0,000 0,05562784 0,12352062 ! response to hexose stimulus GO:0009746 7 7 0,000 0,05562784 0,12337198 GO:0034284|response to monosaccharide stimulus, GO:0009749|response to glucose stimulus, ! membrane protein ectodomain proteolysis GO:0006509 7 7 0,000 0,05562784 0,1232237 GO:0033619|membrane protein proteolysis, ! positive regulation of survival gene product expression GO:0045885 7 7 0,000 0,05562784 0,12307577 ! regulation of skeletal muscle fiber development GO:0048742 7 7 0,000 0,05562784 0,1229282 ! cardiac muscle tissue development GO:0048738 7 7 0,000 0,05562784 0,12278098 ! nucleotide-sugar metabolic process GO:0009225 7 7 0,000 0,05562784 0,12263411 ! complement activation, alternative pathway GO:0006957 7 7 0,000 0,05562784 0,12248759 ! arachidonic acid secretion GO:0050482 7 7 0,000 0,05562784 0,12234143 GO:0032309|icosanoid secretion, ! polyamine biosynthetic process GO:0006596 7 7 0,000 0,05562784 0,12219561 ! UV protection GO:0009650 7 7 0,000 0,05562784 0,12205014 ! DNA integration GO:0015074 7 7 0,000 0,05562784 0,12190501 ! myofibril assembly GO:0030239 7 7 0,000 0,05562784 0,12176023 GO:0055002|striated muscle cell development, ! positive regulation of carbohydrate metabolic process GO:0045913 7 7 0,000 0,05562784 0,12161579 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! positive regulation of muscle contraction GO:0045933 7 7 0,000 0,05562784 0,1214717 ! negative regulation of muscle contraction GO:0045932 7 7 0,000 0,05562784 0,12132795 ! chondroitin sulfate biosynthetic process GO:0030206 7 7 0,000 0,05562784 0,12118453 GO:0030204|chondroitin sulfate metabolic process, ! regulation of exocytosis GO:0017157 8 7 0,000 0,05562784 0,12104146 ! phosphatidylcholine biosynthetic process GO:0006656 7 7 0,000 0,05562784 0,12089872 ! heparan sulfate proteoglycan metabolic process GO:0030201 7 7 0,000 0,05562784 0,12075632 GO:0015012|heparan sulfate proteoglycan biosynthetic process, ! stem cell development GO:0048864 7 7 0,000 0,05562784 0,12061425 GO:0019827|stem cell maintenance, ! alpha-beta T cell differentiation GO:0046632 7 7 0,000 0,05562784 0,12047252 ! negative regulation of myeloid leukocyte differentiation GO:0002762 7 7 0,000 0,05562784 0,12033112 ! NLS-bearing substrate import into nucleus GO:0006607 7 7 0,000 0,05562784 0,12019005 ! axon cargo transport GO:0008088 7 7 0,000 0,05562784 0,12004931 ! eating behavior GO:0042755 7 7 0,000 0,05562784 0,11990891 ! RNA-dependent DNA replication GO:0006278 7 7 0,000 0,05562784 0,11976883 ! purine nucleoside triphosphate catabolic process GO:0009146 7 7 0,000 0,05562784 0,11962907 ! regulation of interleukin-8 production GO:0032677 7 7 0,000 0,05562784 0,11948964 ! purine ribonucleotide catabolic process GO:0009154 7 7 0,000 0,05562784 0,11935054 ! ribosomal small subunit biogenesis GO:0042274 7 7 0,000 0,05562784 0,11921176 ! cranial nerve development GO:0021545 7 7 0,000 0,05562784 0,1190733 ! protein import into peroxisome matrix GO:0016558 7 7 0,000 0,05562784 0,11893517 ! induction of an organ GO:0001759 7 7 0,000 0,05562784 0,11879735 ! leukocyte activation during immune response GO:0002366 7 7 0,000 0,05562784 0,11865986 GO:0002263|cell activation during immune response, ! response to estradiol stimulus GO:0032355 7 7 0,000 0,05562784 0,11852268 ! autonomic nervous system development GO:0048483 7 7 0,000 0,05562784 0,11838581 ! intracellular lipid transport GO:0032365 7 7 0,000 0,05562784 0,11824927 ! detection of chemical stimulus GO:0009593 8 7 0,000 0,05562784 0,11811304 ! platelet activation GO:0030168 8 7 0,000 0,05562784 0,11797712 ! negative regulation of cytokine secretion GO:0050710 7 7 0,000 0,05562784 0,11784151 ! regulation of interleukin-1 secretion GO:0050704 7 7 0,000 0,05562784 0,11770622 ! natural killer cell activation GO:0030101 7 7 0,000 0,05562784 0,11757123 ! NADP metabolic process GO:0006739 7 7 0,000 0,05562784 0,11743656 ! neuromuscular synaptic transmission GO:0007274 7 7 0,000 0,05562784 0,11730219 ! synaptic transmission, cholinergic GO:0007271 7 7 0,000 0,05562784 0,11716813 ! ubiquinone metabolic process GO:0006743 7 7 0,000 0,05562784 0,11703438 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, GO:0042375|quinone cofactor metabolic process, ! regulation of macrophage differentiation GO:0045649 8 7 0,000 0,05562784 0,11690093 ! positive regulation of acute inflammatory response GO:0002675 7 7 0,000 0,05562784 0,11676778 ! regulation of osteoclast differentiation GO:0045670 7 7 0,000 0,05562784 0,11663494 ! negative regulation of cell-substrate adhesion GO:0010812 8 7 0,000 0,05562784 0,1165024 GO:0001953|negative regulation of cell-matrix adhesion, ! multicellular organismal water homeostasis GO:0050891 7 7 0,000 0,05562784 0,11637016 ! regulation of ATPase activity GO:0043462 7 7 0,000 0,05562784 0,11623823 ! cell-cell recognition GO:0009988 8 7 0,000 0,05562784 0,11610659 ! hormone catabolic process GO:0042447 7 7 0,000 0,05562784 0,11597524 ! dopamine metabolic process GO:0042417 7 7 0,000 0,05562784 0,1158442 ! cAMP biosynthetic process GO:0006171 7 7 0,000 0,05562784 0,11571345 ! oxygen transport GO:0015671 7 7 0,000 0,05562784 0,11558299 ! pyridine nucleotide biosynthetic process GO:0019363 7 7 0,000 0,05562784 0,11545283 ! biogenic amine catabolic process GO:0042402 7 7 0,000 0,05562784 0,11532296 ! regulation of axon extension GO:0030516 7 7 0,000 0,05562784 0,11519339 ! cell killing GO:0001906 7 7 0,000 0,05562784 0,1150641 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 7 7 0,000 0,05562784 0,11493511 ! adult feeding behavior GO:0008343 7 7 0,000 0,05562784 0,1148064 ! pyrimidine nucleotide catabolic process GO:0006244 7 7 0,000 0,05562784 0,11467798 ! positive regulation of protein polymerization GO:0032273 7 7 0,000 0,05562784 0,11454985 ! T cell receptor signaling pathway GO:0050852 7 7 0,000 0,05562784 0,114422 ! response to cold GO:0009409 7 7 0,000 0,05562784 0,11429444 ! sex differentiation GO:0007548 47 47 1,000 0,05571565 0,11434738 ! regulation of catabolic process GO:0009894 48 47 1,000 0,05571565 0,11422018 ! glycerophospholipid metabolic process GO:0006650 49 48 1,000 0,05784159 0,11844672 ! protein localization in nucleus GO:0034504 48 48 1,000 0,05784159 0,11831526 ! DNA recombination GO:0006310 48 48 1,000 0,05784159 0,11818409 ! cell cycle arrest GO:0007050 49 49 1,000 0,0599956 0,12244948 ! regulation of neurogenesis GO:0050767 51 50 1,000 0,0621771 0,12676149 ! anatomical structure homeostasis GO:0060249 51 50 1,000 0,0621771 0,12662143 ! anterior/posterior pattern formation GO:0009952 51 50 1,000 0,0621771 0,12648167 ! regulation of skeletal muscle tissue development GO:0048641 8 8 0,000 0,06332242 0,12866949 ! negative regulation of muscle development GO:0048635 8 8 0,000 0,06332242 0,12852778 ! very-long-chain fatty acid metabolic process GO:0000038 8 8 0,000 0,06332242 0,12838638 ! positive regulation of translation GO:0045727 8 8 0,000 0,06332242 0,1282453 ! positive regulation of cell killing GO:0031343 8 8 0,000 0,06332242 0,12810453 ! superoxide anion generation GO:0042554 8 8 0,000 0,06332242 0,12796406 ! sulfur amino acid biosynthetic process GO:0000097 8 8 0,000 0,06332242 0,1278239 ! cGMP metabolic process GO:0046068 8 8 0,000 0,06332242 0,12768405 GO:0006182|cGMP biosynthetic process, ! thyroid gland development GO:0030878 8 8 0,000 0,06332242 0,12754451 ! 'de novo' protein folding GO:0006458 8 8 0,000 0,06332242 0,12740527 ! dicarboxylic acid transport GO:0006835 8 8 0,000 0,06332242 0,12726633 ! phosphoinositide phosphorylation GO:0046854 8 8 0,000 0,06332242 0,12712769 ! embryonic hindlimb morphogenesis GO:0035116 8 8 0,000 0,06332242 0,12698936 ! zinc ion transport GO:0006829 8 8 0,000 0,06332242 0,12685133 ! embryonic forelimb morphogenesis GO:0035115 8 8 0,000 0,06332242 0,1267136 ! folic acid and derivative biosynthetic process GO:0009396 8 8 0,000 0,06332242 0,12657616 ! cardiac muscle contraction GO:0060048 8 8 0,000 0,06332242 0,12643903 ! lipid localization GO:0010876 8 8 0,000 0,06332242 0,12630219 GO:0019915|lipid storage, ! response to pain GO:0048265 8 8 0,000 0,06332242 0,12616565 ! response to cAMP GO:0051591 8 8 0,000 0,06332242 0,1260294 ! COPI coating of Golgi vesicle GO:0048205 8 8 0,000 0,06332242 0,12589345 GO:0048200|Golgi transport vesicle coating, ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 8 0,000 0,06332242 0,12575778 ! negative regulation of ion transport GO:0043271 8 8 0,000 0,06332242 0,12562242 ! regulation of response to extracellular stimulus GO:0032104 8 8 0,000 0,06332242 0,12548734 GO:0032107|regulation of response to nutrient levels, ! adult walking behavior GO:0007628 8 8 0,000 0,06332242 0,12535255 ! sensory perception of taste GO:0050909 8 8 0,000 0,06332242 0,12521805 ! organelle fusion GO:0048284 8 8 0,000 0,06332242 0,12508384 ! pancreas development GO:0031016 8 8 0,000 0,06332242 0,12494992 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 8 8 0,000 0,06332242 0,12481628 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! T cell selection GO:0045058 8 8 0,000 0,06332242 0,12468293 ! negative regulation of proteolysis GO:0045861 8 8 0,000 0,06332242 0,12454987 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 8 8 0,000 0,06332242 0,12441708 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 8 8 0,000 0,06332242 0,12428458 ! sperm motility GO:0030317 8 8 0,000 0,06332242 0,12415237 ! regulation of striated muscle contraction GO:0006942 8 8 0,000 0,06332242 0,12402043 ! DNA duplex unwinding GO:0032508 8 8 0,000 0,06332242 0,12388877 GO:0032392|DNA geometric change, ! glycine metabolic process GO:0006544 8 8 0,000 0,06332242 0,1237574 ! ribonucleotide catabolic process GO:0009261 8 8 0,000 0,06332242 0,1236263 ! negative regulation of microtubule depolymerization GO:0007026 8 8 0,000 0,06332242 0,12349547 GO:0031114|regulation of microtubule depolymerization, ! phosphagen metabolic process GO:0006599 8 8 0,000 0,06332242 0,12336493 GO:0006600|creatine metabolic process, ! polyamine metabolic process GO:0006595 8 8 0,000 0,06332242 0,12323466 ! Golgi organization GO:0007030 8 8 0,000 0,06332242 0,12310467 ! regulation of stress fiber formation GO:0051492 9 8 0,000 0,06332242 0,12297495 ! mannose metabolic process GO:0006013 9 8 0,000 0,06332242 0,1228455 ! NAD metabolic process GO:0019674 8 8 0,000 0,06332242 0,12271632 ! negative regulation of mitotic cell cycle GO:0045930 9 8 0,000 0,06332242 0,12258742 ! plasma membrane fusion GO:0045026 8 8 0,000 0,06332242 0,12245879 ! response to fungus GO:0009620 8 8 0,000 0,06332242 0,12233042 ! stem cell differentiation GO:0048863 8 8 0,000 0,06332242 0,12220233 ! alpha-beta T cell activation GO:0046631 8 8 0,000 0,06332242 0,1220745 ! positive regulation of myeloid leukocyte differentiation GO:0002763 9 8 0,000 0,06332242 0,12194694 ! embryonic digit morphogenesis GO:0042733 8 8 0,000 0,06332242 0,12181965 ! regulation of cytokine production during immune response GO:0002718 8 8 0,000 0,06332242 0,12169262 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 0,06332242 0,12156586 ! regulation of vasodilation GO:0042312 8 8 0,000 0,06332242 0,12143936 ! vasoconstriction GO:0042310 8 8 0,000 0,06332242 0,12131312 ! regulation of T cell mediated immunity GO:0002709 8 8 0,000 0,06332242 0,12118715 ! muscle cell development GO:0055001 8 8 0,000 0,06332242 0,12106144 ! nucleoside triphosphate catabolic process GO:0009143 8 8 0,000 0,06332242 0,12093598 ! regulation of fatty acid metabolic process GO:0019217 8 8 0,000 0,06332242 0,12081079 ! sensory perception of pain GO:0019233 8 8 0,000 0,06332242 0,12068586 ! gastrulation with mouth forming second GO:0001702 8 8 0,000 0,06332242 0,12056118 ! mRNA cleavage GO:0006379 8 8 0,000 0,06332242 0,12043676 ! chromatin silencing GO:0006342 8 8 0,000 0,06332242 0,1203126 ! tissue regeneration GO:0042246 8 8 0,000 0,06332242 0,1201887 ! salivary gland development GO:0007431 8 8 0,000 0,06332242 0,12006505 ! peptide biosynthetic process GO:0043043 9 8 0,000 0,06332242 0,11994165 ! water homeostasis GO:0030104 8 8 0,000 0,06332242 0,1198185 ! cofactor transport GO:0051181 8 8 0,000 0,06332242 0,11969561 ! regulation of acute inflammatory response GO:0002673 8 8 0,000 0,06332242 0,11957298 ! acid secretion GO:0046717 8 8 0,000 0,06332242 0,11945059 ! C21-steroid hormone biosynthetic process GO:0006700 8 8 0,000 0,06332242 0,11932845 ! protein-chromophore linkage GO:0018298 9 8 0,000 0,06332242 0,11920656 ! regulation of immunoglobulin production GO:0002637 8 8 0,000 0,06332242 0,11908492 ! branched chain family amino acid metabolic process GO:0009081 8 8 0,000 0,06332242 0,11896353 ! catecholamine biosynthetic process GO:0042423 8 8 0,000 0,06332242 0,11884239 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 8 8 0,000 0,06332242 0,11872149 ! regulation of generation of precursor metabolites and energy GO:0043467 8 8 0,000 0,06332242 0,11860084 ! aromatic compound biosynthetic process GO:0019438 8 8 0,000 0,06332242 0,11848043 ! regulation of organic acid transport GO:0032890 8 8 0,000 0,06332242 0,11836027 ! positive regulation of calcium ion transport GO:0051928 8 8 0,000 0,06332242 0,11824035 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 8 8 0,000 0,06332242 0,11812067 ! regulation of multi-organism process GO:0043900 8 8 0,000 0,06332242 0,11800124 ! positive regulation of amine transport GO:0051954 8 8 0,000 0,06332242 0,11788204 ! developmental induction GO:0031128 8 8 0,000 0,06332242 0,11776309 GO:0045168|cell-cell signaling involved in cell fate specification, ! peptide hormone secretion GO:0030072 8 8 0,000 0,06332242 0,11764438 ! positive regulation of calcium-mediated signaling GO:0050850 8 8 0,000 0,06332242 0,11752591 ! actin filament polymerization GO:0030041 9 8 0,000 0,06332242 0,11740767 ! peptide hormone processing GO:0016486 8 8 0,000 0,06332242 0,11728967 ! positive regulation of synaptic transmission GO:0050806 8 8 0,000 0,06332242 0,11717191 ! regulation of steroid biosynthetic process GO:0050810 8 8 0,000 0,06332242 0,11705439 ! rRNA metabolic process GO:0016072 51 51 1,000 0,06438552 0,11890031 GO:0006364|rRNA processing, ! regulation of body fluid levels GO:0050878 55 52 1,000 0,0666203 0,12290411 ! sodium ion transport GO:0006814 53 53 1,000 0,06888087 0,12694745 ! carbohydrate biosynthetic process GO:0016051 53 53 1,000 0,06888087 0,12682063 ! carbohydrate catabolic process GO:0016052 53 53 1,000 0,06888087 0,12669406 ! lactation GO:0007595 10 9 0,000 0,07095542 0,1303797 ! embryonic pattern specification GO:0009880 10 9 0,000 0,07095542 0,13024983 ! positive regulation of cell size GO:0045793 9 9 0,000 0,07095542 0,13012023 ! positive regulation of cell projection organization GO:0031346 9 9 0,000 0,07095542 0,12999089 ! regulation of membrane protein ectodomain proteolysis GO:0051043 9 9 0,000 0,07095542 0,1298618 ! positive regulation of protein complex assembly GO:0031334 9 9 0,000 0,07095542 0,12973297 ! cortical actin cytoskeleton organization GO:0030866 10 9 0,000 0,07095542 0,12960439 ! negative regulation of cell cycle process GO:0010948 9 9 0,000 0,07095542 0,12947607 ! viral genome replication GO:0019079 9 9 0,000 0,07095542 0,12934801 ! phospholipid catabolic process GO:0009395 9 9 0,000 0,07095542 0,12922019 ! copper ion transport GO:0006825 9 9 0,000 0,07095542 0,12909263 ! lipid phosphorylation GO:0046834 9 9 0,000 0,07095542 0,12896532 ! aminoglycan catabolic process GO:0006026 9 9 0,000 0,07095542 0,12883826 ! Golgi vesicle budding GO:0048194 9 9 0,000 0,07095542 0,12871145 ! regulation of cell-cell adhesion GO:0022407 9 9 0,000 0,07095542 0,12858489 ! RNA polyadenylation GO:0043631 9 9 0,000 0,07095542 0,12845858 GO:0006378|mRNA polyadenylation, ! gamma-aminobutyric acid signaling pathway GO:0007214 9 9 0,000 0,07095542 0,12833252 ! regulation of postsynaptic membrane potential GO:0060078 9 9 0,000 0,07095542 0,1282067 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 9 9 0,000 0,07095542 0,12808113 ! negative regulation of cytokine biosynthetic process GO:0042036 9 9 0,000 0,07095542 0,12795581 ! phospholipid efflux GO:0033700 9 9 0,000 0,07095542 0,12783073 ! response to alkaloid GO:0043279 10 9 0,000 0,07095542 0,12770589 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 9 9 0,000 0,07095542 0,1275813 ! cytokine biosynthetic process GO:0042089 9 9 0,000 0,07095542 0,12745695 GO:0042107|cytokine metabolic process, ! negative regulation of gene expression, epigenetic GO:0045814 9 9 0,000 0,07095542 0,12733285 ! regulation of interleukin-2 biosynthetic process GO:0045076 9 9 0,000 0,07095542 0,12720898 ! response to ethanol GO:0045471 9 9 0,000 0,07095542 0,12708536 ! pyrimidine ribonucleotide metabolic process GO:0009218 9 9 0,000 0,07095542 0,12696198 ! activation of pro-apoptotic gene products GO:0008633 9 9 0,000 0,07095542 0,12683883 ! methionine metabolic process GO:0006555 9 9 0,000 0,07095542 0,12671592 ! cerebral cortex development GO:0021987 9 9 0,000 0,07095542 0,12659326 ! response to osmotic stress GO:0006970 9 9 0,000 0,07095542 0,12647083 ! pigmentation during development GO:0048066 9 9 0,000 0,07095542 0,12634863 ! reverse cholesterol transport GO:0043691 9 9 0,000 0,07095542 0,12622667 ! central nervous system neuron development GO:0021954 10 9 0,000 0,07095542 0,12610495 ! pyrimidine ribonucleoside metabolic process GO:0046131 9 9 0,000 0,07095542 0,12598346 ! substrate-bound cell migration GO:0006929 9 9 0,000 0,07095542 0,12586221 ! neurotransmitter metabolic process GO:0042133 11 9 0,000 0,07095542 0,12574119 ! negative regulation of caspase activity GO:0043154 9 9 0,000 0,07095542 0,1256204 ! branching involved in ureteric bud morphogenesis GO:0001658 9 9 0,000 0,07095542 0,12549984 GO:0060675|ureteric bud morphogenesis, ! L-glutamate transport GO:0015813 9 9 0,000 0,07095542 0,12537952 GO:0015800|acidic amino acid transport, ! peptide secretion GO:0002790 9 9 0,000 0,07095542 0,12525942 ! regulation of dephosphorylation GO:0035303 9 9 0,000 0,07095542 0,12513955 ! cotranslational protein targeting to membrane GO:0006613 10 9 0,000 0,07095542 0,12501992 ! positive regulation of alpha-beta T cell differentiation GO:0046638 9 9 0,000 0,07095542 0,12490051 ! ventricular cardiac muscle morphogenesis GO:0055010 9 9 0,000 0,07095542 0,12478133 ! behavioral interaction between organisms GO:0051705 9 9 0,000 0,07095542 0,12466238 ! DNA replication initiation GO:0006270 9 9 0,000 0,07095542 0,12454365 ! prostaglandin metabolic process GO:0006693 9 9 0,000 0,07095542 0,12442515 GO:0006692|prostanoid metabolic process, ! T cell differentiation in the thymus GO:0033077 9 9 0,000 0,07095542 0,12430688 ! regulation of immunoglobulin mediated immune response GO:0002889 9 9 0,000 0,07095542 0,12418883 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 10 9 0,000 0,07095542 0,124071 ! positive regulation of oxidoreductase activity GO:0051353 9 9 0,000 0,07095542 0,1239534 ! positive regulation of cytokine secretion GO:0050715 9 9 0,000 0,07095542 0,12383602 ! negative regulation of inflammatory response GO:0050728 9 9 0,000 0,07095542 0,12371886 ! negative regulation of protein secretion GO:0050709 9 9 0,000 0,07095542 0,12360192 ! positive regulation of transmission of nerve impulse GO:0051971 9 9 0,000 0,07095542 0,12348521 ! collagen catabolic process GO:0030574 9 9 0,000 0,07095542 0,12336871 ! aromatic amino acid family catabolic process GO:0009074 9 9 0,000 0,07095542 0,12325244 ! gas transport GO:0015669 9 9 0,000 0,07095542 0,12313638 ! cholesterol efflux GO:0033344 9 9 0,000 0,07095542 0,12302054 ! regulation of leukocyte mediated cytotoxicity GO:0001910 9 9 0,000 0,07095542 0,12290492 ! estrogen receptor signaling pathway GO:0030520 9 9 0,000 0,07095542 0,12278952 ! regulation of actin filament bundle formation GO:0032231 10 9 0,000 0,07095542 0,12267433 ! defense response to virus GO:0051607 9 9 0,000 0,07095542 0,12255936 ! regulation of calcium-mediated signaling GO:0050848 9 9 0,000 0,07095542 0,1224446 ! actin filament-based movement GO:0030048 9 9 0,000 0,07095542 0,12233006 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 9 9 0,000 0,07095542 0,12221573 ! hormone metabolic process GO:0042445 55 54 1,000 0,0711667 0,1224652 ! in utero embryonic development GO:0001701 55 55 1,000 0,07347723 0,12632326 ! regulation of cell adhesion GO:0030155 56 55 1,000 0,07347723 0,12620553 ! extracellular structure organization GO:0043062 56 56 1,000 0,07581193 0,1300944 ! regulation of nervous system development GO:0051960 57 56 1,000 0,07581193 0,12997338 ! protein import into nucleus, docking GO:0000059 10 10 0,000 0,07852731 0,13450357 ! regulation of protein ubiquitination GO:0031396 10 10 0,000 0,07852731 0,13437868 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 10 10 0,000 0,07852731 0,13425402 ! regulation of glucose metabolic process GO:0010906 10 10 0,000 0,07852731 0,1341296 ! ER-associated protein catabolic process GO:0030433 10 10 0,000 0,07852731 0,13400541 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of cell killing GO:0031341 10 10 0,000 0,07852731 0,13388144 ! neuron maturation GO:0042551 10 10 0,000 0,07852731 0,13375771 ! pteridine and derivative metabolic process GO:0042558 10 10 0,000 0,07852731 0,1336342 ! positive regulation of anti-apoptosis GO:0045768 10 10 0,000 0,07852731 0,13351092 GO:0045767|regulation of anti-apoptosis, ! cortical cytoskeleton organization GO:0030865 11 10 0,000 0,07852731 0,13338787 ! regulation of lipid biosynthetic process GO:0046890 10 10 0,000 0,07852731 0,13326504 ! reciprocal meiotic recombination GO:0007131 10 10 0,000 0,07852731 0,13314245 ! hormone secretion GO:0046879 10 10 0,000 0,07852731 0,13302007 ! glucosamine metabolic process GO:0006041 10 10 0,000 0,07852731 0,13289792 GO:0006044|N-acetylglucosamine metabolic process, ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 10 10 0,000 0,07852731 0,132776 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! inositol metabolic process GO:0006020 10 10 0,000 0,07852731 0,1326543 ! cAMP metabolic process GO:0046058 10 10 0,000 0,07852731 0,13253282 ! vesicle targeting, to, from or within Golgi GO:0048199 10 10 0,000 0,07852731 0,13241156 ! transcription from RNA polymerase III promoter GO:0006383 10 10 0,000 0,07852731 0,13229053 ! forelimb morphogenesis GO:0035136 10 10 0,000 0,07852731 0,13216972 ! glial cell development GO:0021782 10 10 0,000 0,07852731 0,13204912 ! phototransduction GO:0007602 11 10 0,000 0,07852731 0,13192875 ! auditory receptor cell differentiation GO:0042491 10 10 0,000 0,07852731 0,1318086 ! fat cell differentiation GO:0045444 10 10 0,000 0,07852731 0,13168866 ! myoblast differentiation GO:0045445 10 10 0,000 0,07852731 0,13156894 ! centrosome cycle GO:0007098 10 10 0,000 0,07852731 0,13144944 ! inactivation of MAPK activity GO:0000188 10 10 0,000 0,07852731 0,13133016 ! positive regulation of proteolysis GO:0045862 10 10 0,000 0,07852731 0,1312111 ! response to carbohydrate stimulus GO:0009743 10 10 0,000 0,07852731 0,13109224 ! regulation of survival gene product expression GO:0045884 10 10 0,000 0,07852731 0,13097361 ! epidermis morphogenesis GO:0048730 10 10 0,000 0,07852731 0,13085519 ! protein polyubiquitination GO:0000209 10 10 0,000 0,07852731 0,13073698 ! glutamate metabolic process GO:0006536 11 10 0,000 0,07852731 0,13061899 ! plasma membrane organization GO:0007009 10 10 0,000 0,07852731 0,13050121 ! cell-substrate junction assembly GO:0007044 11 10 0,000 0,07852731 0,13038364 ! lysosomal transport GO:0007041 10 10 0,000 0,07852731 0,13026628 ! cellular response to unfolded protein GO:0034620 10 10 0,000 0,07852731 0,13014914 GO:0030968|endoplasmic reticulum unfolded protein response, ! central nervous system neuron differentiation GO:0021953 11 10 0,000 0,07852731 0,1300322 ! purine ribonucleoside metabolic process GO:0046128 10 10 0,000 0,07852731 0,12991547 GO:0042278|purine nucleoside metabolic process, ! vesicle coating GO:0006901 10 10 0,000 0,07852731 0,12979896 ! exocrine system development GO:0035272 10 10 0,000 0,07852731 0,12968265 ! embryo implantation GO:0007566 11 10 0,000 0,07852731 0,12956655 ! regulation of protein binding GO:0043393 11 10 0,000 0,07852731 0,12945066 ! protein targeting to peroxisome GO:0006625 10 10 0,000 0,07852731 0,12933498 ! protein targeting to mitochondrion GO:0006626 10 10 0,000 0,07852731 0,1292195 GO:0070585|protein localization in mitochondrion, ! regulation of alpha-beta T cell differentiation GO:0046637 10 10 0,000 0,07852731 0,12910423 ! intermediate filament cytoskeleton organization GO:0045104 10 10 0,000 0,07852731 0,12898916 ! protein export from nucleus GO:0006611 10 10 0,000 0,07852731 0,1288743 ! negative regulation of immune response GO:0050777 10 10 0,000 0,07852731 0,12875964 ! cytolysis GO:0019835 10 10 0,000 0,07852731 0,12864519 ! positive regulation of biomineral formation GO:0070169 10 10 0,000 0,07852731 0,12853094 GO:0030501|positive regulation of bone mineralization, ! regulation of B cell differentiation GO:0045577 10 10 0,000 0,07852731 0,12841689 ! histone deacetylation GO:0016575 10 10 0,000 0,07852731 0,12830305 ! mRNA splice site selection GO:0006376 11 10 0,000 0,07852731 0,12818941 ! gland morphogenesis GO:0022612 10 10 0,000 0,07852731 0,12807596 ! positive regulation of neurological system process GO:0031646 10 10 0,000 0,07852731 0,12796272 ! sphingolipid biosynthetic process GO:0030148 10 10 0,000 0,07852731 0,12784968 GO:0046467|membrane lipid biosynthetic process, ! sphingolipid catabolic process GO:0030149 10 10 0,000 0,07852731 0,12773684 GO:0046466|membrane lipid catabolic process, ! nerve-nerve synaptic transmission GO:0007270 10 10 0,000 0,07852731 0,1276242 ! regulation of erythrocyte differentiation GO:0045646 10 10 0,000 0,07852731 0,12751175 ! regulation of epidermis development GO:0045682 10 10 0,000 0,07852731 0,12739951 ! folic acid and derivative metabolic process GO:0006760 10 10 0,000 0,07852731 0,12728746 ! negative regulation of neuron differentiation GO:0045665 10 10 0,000 0,07852731 0,1271756 ! aspartate family amino acid biosynthetic process GO:0009067 10 10 0,000 0,07852731 0,12706395 ! nerve development GO:0021675 10 10 0,000 0,07852731 0,12695249 ! epithelial to mesenchymal transition GO:0001837 10 10 0,000 0,07852731 0,12684123 ! gut development GO:0048565 10 10 0,000 0,07852731 0,12673016 ! embryonic organ morphogenesis GO:0048562 10 10 0,000 0,07852731 0,12661928 ! mRNA 3'-end processing GO:0031124 10 10 0,000 0,07852731 0,1265086 ! antigen receptor-mediated signaling pathway GO:0050851 10 10 0,000 0,07852731 0,12639811 ! regulation of cell development GO:0060284 60 59 1,000 0,08295576 0,13340966 ! cellular aromatic compound metabolic process GO:0006725 60 59 1,000 0,08295576 0,13329335 ! protein localization in organelle GO:0033365 59 59 1,000 0,08295576 0,13317724 ! immune effector process GO:0002252 59 59 1,000 0,08295576 0,13306133 ! protein polymerization GO:0051258 65 60 1,000 0,0853819 0,13683378 ! protein secretion GO:0009306 11 11 0,000 0,08603859 0,1377664 ! oligosaccharide metabolic process GO:0009311 11 11 0,000 0,08603859 0,13764681 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 11 11 0,000 0,08603859 0,13752743 ! myeloid leukocyte differentiation GO:0002573 12 11 0,000 0,08603859 0,13740825 ! negative regulation of defense response GO:0031348 11 11 0,000 0,08603859 0,13728928 ! determination of bilateral symmetry GO:0009855 11 11 0,000 0,08603859 0,13717052 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! positive regulation of hormone secretion GO:0046887 11 11 0,000 0,08603859 0,13705196 ! skin development GO:0043588 11 11 0,000 0,08603859 0,13693361 ! cellular component assembly involved in morphogenesis GO:0010927 11 11 0,000 0,08603859 0,13681546 ! microtubule-based transport GO:0010970 11 11 0,000 0,08603859 0,13669752 ! endothelial cell migration GO:0043542 11 11 0,000 0,08603859 0,13657978 ! peroxisomal transport GO:0043574 11 11 0,000 0,08603859 0,13646224 ! protein amino acid methylation GO:0006479 11 11 0,000 0,08603859 0,1363449 GO:0008213|protein amino acid alkylation, ! heart contraction GO:0060047 11 11 0,000 0,08603859 0,13622777 GO:0003015|heart process, ! detection of light stimulus involved in sensory perception GO:0050962 12 11 0,000 0,08603859 0,13611083 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 11 11 0,000 0,08603859 0,1359941 ! T cell proliferation GO:0042098 11 11 0,000 0,08603859 0,13587757 ! negative regulation of endothelial cell proliferation GO:0001937 11 11 0,000 0,08603859 0,13576123 ! regulation of viral genome replication GO:0045069 11 11 0,000 0,08603859 0,1356451 ! spinal cord development GO:0021510 11 11 0,000 0,08603859 0,13552916 ! activation of MAPKK activity GO:0000186 12 11 0,000 0,08603859 0,13541343 ! smooth muscle contraction GO:0006939 11 11 0,000 0,08603859 0,13529789 ! cellular macromolecular complex disassembly GO:0034623 12 11 0,000 0,08603859 0,13518254 ! digestive system process GO:0022600 11 11 0,000 0,08603859 0,13506739 ! mitotic spindle organization GO:0007052 11 11 0,000 0,08603859 0,13495244 ! fucose metabolic process GO:0006004 11 11 0,000 0,08603859 0,13483769 ! membrane budding GO:0006900 11 11 0,000 0,08603859 0,13472313 ! monoamine transport GO:0015844 11 11 0,000 0,08603859 0,13460876 ! regulation of cellular ketone metabolic process GO:0010565 11 11 0,000 0,08603859 0,13449459 ! response to lipopolysaccharide GO:0032496 11 11 0,000 0,08603859 0,13438061 ! body fluid secretion GO:0007589 11 11 0,000 0,08603859 0,13426683 ! positive regulation of alpha-beta T cell activation GO:0046635 11 11 0,000 0,08603859 0,13415323 ! intermediate filament-based process GO:0045103 11 11 0,000 0,08603859 0,13403983 ! cardiac muscle tissue morphogenesis GO:0055008 11 11 0,000 0,08603859 0,13392662 GO:0060415|muscle tissue morphogenesis, ! interaction with host GO:0051701 11 11 0,000 0,08603859 0,1338136 ! membrane depolarization GO:0051899 11 11 0,000 0,08603859 0,13370078 ! regulation of interleukin-2 production GO:0032663 11 11 0,000 0,08603859 0,13358814 ! regulation of ARF GTPase activity GO:0032312 11 11 0,000 0,08603859 0,13347569 ! oogenesis GO:0048477 11 11 0,000 0,08603859 0,13336343 ! negative regulation of angiogenesis GO:0016525 11 11 0,000 0,08603859 0,13325136 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 11 11 0,000 0,08603859 0,13313948 ! regulation of cellular carbohydrate metabolic process GO:0010675 11 11 0,000 0,08603859 0,13302779 GO:0006109|regulation of carbohydrate metabolic process, ! vitamin transport GO:0051180 11 11 0,000 0,08603859 0,13291628 ! vitamin A metabolic process GO:0006776 11 11 0,000 0,08603859 0,13280496 ! hindbrain development GO:0030902 11 11 0,000 0,08603859 0,13269383 ! steroid catabolic process GO:0006706 11 11 0,000 0,08603859 0,13258288 ! endocrine process GO:0050886 11 11 0,000 0,08603859 0,13247211 GO:0001990|regulation of systemic arterial blood pressure by hormone, ! aromatic amino acid family metabolic process GO:0009072 11 11 0,000 0,08603859 0,13236154 ! proximal/distal pattern formation GO:0009954 11 11 0,000 0,08603859 0,13225114 ! RNA 3'-end processing GO:0031123 11 11 0,000 0,08603859 0,13214093 ! morphogenesis of an epithelium GO:0002009 63 62 1,000 0,09029844 0,13856787 GO:0060429|epithelium development, ! axonogenesis GO:0007409 66 62 1,000 0,09029844 0,13845259 ! protein import GO:0017038 62 62 1,000 0,09029844 0,1383375 ! positive regulation of protein catabolic process GO:0045732 12 12 0,000 0,09348972 0,14310761 ! translational initiation GO:0006413 12 12 0,000 0,09348972 0,14298885 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 12 12 0,000 0,09348972 0,14287028 ! positive regulation of angiogenesis GO:0045766 12 12 0,000 0,09348972 0,14275191 ! initiation of viral infection GO:0019059 12 12 0,000 0,09348972 0,14263374 ! iron ion transport GO:0006826 13 12 0,000 0,09348972 0,14251577 ! phosphatidylcholine metabolic process GO:0046470 12 12 0,000 0,09348972 0,14239798 ! amino sugar metabolic process GO:0006040 12 12 0,000 0,09348972 0,1422804 ! protein amino acid ADP-ribosylation GO:0006471 12 12 0,000 0,09348972 0,142163 ! heterophilic cell adhesion GO:0007157 12 12 0,000 0,09348972 0,1420458 ! collagen metabolic process GO:0032963 12 12 0,000 0,09348972 0,1419288 ! hindlimb morphogenesis GO:0035137 12 12 0,000 0,09348972 0,14181198 ! xenobiotic metabolic process GO:0006805 12 12 0,000 0,09348972 0,14169536 ! glutamate signaling pathway GO:0007215 12 12 0,000 0,09348972 0,14157893 ! C21-steroid hormone metabolic process GO:0008207 13 12 0,000 0,09348972 0,14146269 ! regulation of muscle cell differentiation GO:0051147 13 12 0,000 0,09348972 0,14134665 ! cellular response to hydrogen peroxide GO:0070301 12 12 0,000 0,09348972 0,14123079 GO:0042744|hydrogen peroxide catabolic process, ! negative regulation of peptidase activity GO:0010466 12 12 0,000 0,09348972 0,14111512 ! actomyosin structure organization GO:0031032 12 12 0,000 0,09348972 0,14099964 ! microtubule organizing center organization GO:0031023 12 12 0,000 0,09348972 0,14088435 GO:0051297|centrosome organization, ! retinoid metabolic process GO:0001523 12 12 0,000 0,09348972 0,14076925 GO:0016101|diterpenoid metabolic process, ! mitotic chromosome condensation GO:0007076 12 12 0,000 0,09348972 0,14065434 ! positive regulation of innate immune response GO:0045089 12 12 0,000 0,09348972 0,14053961 ! GPI anchor biosynthetic process GO:0006506 12 12 0,000 0,09348972 0,14042507 GO:0006505|GPI anchor metabolic process, ! glycoprotein catabolic process GO:0006516 13 12 0,000 0,09348972 0,14031072 ! acute-phase response GO:0006953 12 12 0,000 0,09348972 0,14019655 ! deoxyribonucleotide catabolic process GO:0009264 12 12 0,000 0,09348972 0,14008257 ! vacuolar transport GO:0007034 12 12 0,000 0,09348972 0,13996877 ! polysaccharide catabolic process GO:0000272 12 12 0,000 0,09348972 0,13985516 ! vesicle docking during exocytosis GO:0006904 12 12 0,000 0,09348972 0,13974174 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 12 12 0,000 0,09348972 0,13962849 ! barbed-end actin filament capping GO:0051016 12 12 0,000 0,09348972 0,13951543 GO:0051693|actin filament capping, ! osteoblast differentiation GO:0001649 12 12 0,000 0,09348972 0,13940256 ! male gonad development GO:0008584 12 12 0,000 0,09348972 0,13928986 ! regulation of insulin secretion GO:0050796 12 12 0,000 0,09348972 0,13917735 ! regulation of alpha-beta T cell activation GO:0046634 12 12 0,000 0,09348972 0,13906502 ! renal system process GO:0003014 12 12 0,000 0,09348972 0,13895287 ! regulation of tumor necrosis factor production GO:0032680 12 12 0,000 0,09348972 0,1388409 ! regulation of steroid metabolic process GO:0019218 12 12 0,000 0,09348972 0,13872912 ! regulation of interleukin-6 production GO:0032675 12 12 0,000 0,09348972 0,13861751 ! pallium development GO:0021543 13 12 0,000 0,09348972 0,13850608 ! cell fate determination GO:0001709 12 12 0,000 0,09348972 0,13839483 ! regulation of chromosome organization GO:0033044 12 12 0,000 0,09348972 0,13828376 ! positive regulation of multicellular organism growth GO:0040018 12 12 0,000 0,09348972 0,13817286 ! regulation of response to biotic stimulus GO:0002831 12 12 0,000 0,09348972 0,13806215 ! positive regulation of adaptive immune response GO:0002821 12 12 0,000 0,09348972 0,13795161 ! detection of light stimulus GO:0009583 13 12 0,000 0,09348972 0,13784125 ! synaptogenesis GO:0007416 12 12 0,000 0,09348972 0,13773106 ! fat-soluble vitamin metabolic process GO:0006775 12 12 0,000 0,09348972 0,13762106 ! hormone transport GO:0009914 12 12 0,000 0,09348972 0,13751122 ! neurotransmitter secretion GO:0007269 14 12 0,000 0,09348972 0,13740156 ! heme biosynthetic process GO:0006783 12 12 0,000 0,09348972 0,13729208 ! spermatid differentiation GO:0048515 13 12 0,000 0,09348972 0,13718277 GO:0007286|spermatid development, ! aromatic compound catabolic process GO:0019439 13 12 0,000 0,09348972 0,13707364 ! pyrimidine nucleotide biosynthetic process GO:0006221 12 12 0,000 0,09348972 0,13696467 ! neural tube closure GO:0001843 13 12 0,000 0,09348972 0,13685589 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! regulation of mitotic metaphase/anaphase transition GO:0030071 13 12 0,000 0,09348972 0,13674727 ! negative regulation of translation GO:0017148 12 12 0,000 0,09348972 0,13663883 ! regulation of microtubule polymerization or depolymerization GO:0031110 12 12 0,000 0,09348972 0,13653056 ! glycerolipid metabolic process GO:0046486 65 64 1,000 0,09529737 0,13906022 ! regulation of cytoskeleton organization GO:0051493 66 64 1,000 0,09529737 0,1389502 ! anion transport GO:0006820 65 65 1,000 0,09782653 0,14252514 ! positive regulation of cellular component organization GO:0051130 65 65 1,000 0,09782653 0,14241256 ! regulation of hormone levels GO:0010817 66 65 1,000 0,09782653 0,14230016 ! negative regulation of protein metabolic process GO:0051248 66 66 1,000 0,10037486 0,14589185 ! positive regulation of DNA replication GO:0045740 14 13 0,000 0,10088119 0,14651224 ! negative regulation of actin filament polymerization GO:0030837 13 13 0,000 0,10088119 0,14639687 ! phenol metabolic process GO:0018958 13 13 0,000 0,10088119 0,14628169 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, GO:0009712|catechol metabolic process, ! negative regulation of hormone secretion GO:0046888 13 13 0,000 0,10088119 0,14616669 ! 2'-deoxyribonucleotide metabolic process GO:0009394 13 13 0,000 0,10088119 0,14605187 GO:0019692|deoxyribose phosphate metabolic process, ! intra-Golgi vesicle-mediated transport GO:0006891 13 13 0,000 0,10088119 0,14593723 ! glycosaminoglycan biosynthetic process GO:0006024 13 13 0,000 0,10088119 0,14582277 ! positive regulation of JAK-STAT cascade GO:0046427 13 13 0,000 0,10088119 0,14570849 ! regeneration GO:0031099 13 13 0,000 0,10088119 0,14559438 ! keratinization GO:0031424 13 13 0,000 0,10088119 0,14548046 ! post-embryonic development GO:0009791 14 13 0,000 0,10088119 0,14536672 ! negative regulation of protein modification process GO:0031400 13 13 0,000 0,10088119 0,14525315 ! patterning of blood vessels GO:0001569 13 13 0,000 0,10088119 0,14513976 ! regulation of innate immune response GO:0045088 13 13 0,000 0,10088119 0,14502654 ! multicellular organismal macromolecule metabolic process GO:0044259 13 13 0,000 0,10088119 0,14491351 ! response to corticosteroid stimulus GO:0031960 13 13 0,000 0,10088119 0,14480065 GO:0051384|response to glucocorticoid stimulus, ! multicellular organismal catabolic process GO:0044243 13 13 0,000 0,10088119 0,14468796 ! autophagy GO:0006914 13 13 0,000 0,10088119 0,14457545 ! ureteric bud development GO:0001657 13 13 0,000 0,10088119 0,14446312 ! coenzyme catabolic process GO:0009109 13 13 0,000 0,10088119 0,14435095 GO:0046356|acetyl-CoA catabolic process, GO:0006099|tricarboxylic acid cycle, ! negative regulation of protein kinase cascade GO:0010741 13 13 0,000 0,10088119 0,14423897 ! regulation of peptide secretion GO:0002791 13 13 0,000 0,10088119 0,14412715 ! regulation of viral reproduction GO:0050792 13 13 0,000 0,10088119 0,14401551 ! regulation of axonogenesis GO:0050770 14 13 0,000 0,10088119 0,14390405 ! positive regulation of neurogenesis GO:0050769 13 13 0,000 0,10088119 0,14379275 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 14 13 0,000 0,10088119 0,14368163 ! nucleotide-excision repair, DNA gap filling GO:0006297 13 13 0,000 0,10088119 0,14357068 ! vasodilation GO:0042311 14 13 0,000 0,10088119 0,1434599 ! positive regulation of leukocyte mediated immunity GO:0002705 13 13 0,000 0,10088119 0,14334929 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 13 13 0,000 0,10088119 0,14323885 ! glycosphingolipid metabolic process GO:0006687 13 13 0,000 0,10088119 0,14312858 GO:0006664|glycolipid metabolic process, ! neural crest cell migration GO:0001755 14 13 0,000 0,10088119 0,14301848 ! neutrophil chemotaxis GO:0030593 14 13 0,000 0,10088119 0,14290855 ! long-chain fatty acid transport GO:0015909 13 13 0,000 0,10088119 0,14279879 ! regulation of cell-substrate adhesion GO:0010810 14 13 0,000 0,10088119 0,1426892 GO:0001952|regulation of cell-matrix adhesion, ! negative regulation of myeloid cell differentiation GO:0045638 13 13 0,000 0,10088119 0,14257978 ! response to cytokine stimulus GO:0034097 13 13 0,000 0,10088119 0,14247052 ! terpenoid metabolic process GO:0006721 13 13 0,000 0,10088119 0,14236143 ! alkene biosynthetic process GO:0043450 13 13 0,000 0,10088119 0,14225251 GO:0019370|leukotriene biosynthetic process, ! purine nucleotide catabolic process GO:0006195 13 13 0,000 0,10088119 0,14214375 ! porphyrin biosynthetic process GO:0006779 13 13 0,000 0,10088119 0,14203516 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of cytokine production GO:0001818 13 13 0,000 0,10088119 0,14192674 ! camera-type eye morphogenesis GO:0048593 13 13 0,000 0,10088119 0,14181848 ! pyrimidine nucleoside metabolic process GO:0006213 13 13 0,000 0,10088119 0,14171039 ! blastocyst development GO:0001824 13 13 0,000 0,10088119 0,14160246 ! telomere organization GO:0032200 13 13 0,000 0,10088119 0,1414947 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 13 13 0,000 0,10088119 0,14138709 ! regulation of amine transport GO:0051952 13 13 0,000 0,10088119 0,14127966 ! tissue homeostasis GO:0001894 13 13 0,000 0,10088119 0,14117238 GO:0048871|multicellular organismal homeostasis, ! inner ear receptor cell differentiation GO:0060113 13 13 0,000 0,10088119 0,14106527 ! cell morphogenesis involved in neuron differentiation GO:0048667 72 67 1,000 0,10294188 0,14383767 GO:0048812|neuron projection morphogenesis, GO:0048858|cell projection morphogenesis, ! Golgi vesicle transport GO:0048193 67 67 1,000 0,10294188 0,1437287 ! negative regulation of cell differentiation GO:0045596 68 67 1,000 0,10294188 0,1436199 ! purine ribonucleotide biosynthetic process GO:0009152 68 68 1,000 0,10552715 0,14711538 ! regulation of cell size GO:0008361 68 68 1,000 0,10552715 0,14700418 ! response to nutrient levels GO:0031667 69 69 1,000 0,1081302 0,15051658 ! neuron fate commitment GO:0048663 14 14 0,000 0,10821345 0,15051879 ! sulfur amino acid metabolic process GO:0000096 14 14 0,000 0,10821345 0,15040527 ! regulation of interferon-gamma production GO:0032649 14 14 0,000 0,10821345 0,15029193 ! cellular aldehyde metabolic process GO:0006081 14 14 0,000 0,10821345 0,15017876 ! acetyl-CoA metabolic process GO:0006084 14 14 0,000 0,10821345 0,15006576 ! cellular iron ion homeostasis GO:0006879 14 14 0,000 0,10821345 0,14995293 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 14 14 0,000 0,10821345 0,14984026 ! regulation of neuron projection development GO:0010975 15 14 0,000 0,10821345 0,14972777 ! protein amino acid deacetylation GO:0006476 14 14 0,000 0,10821345 0,14961545 ! aminoglycan biosynthetic process GO:0006023 14 14 0,000 0,10821345 0,14950329 ! vesicle docking GO:0048278 14 14 0,000 0,10821345 0,1493913 ! superoxide metabolic process GO:0006801 15 14 0,000 0,10821345 0,14927948 ! macromolecular complex disassembly GO:0032984 15 14 0,000 0,10821345 0,14916783 ! calcium-dependent cell-cell adhesion GO:0016339 14 14 0,000 0,10821345 0,14905635 ! mechanoreceptor differentiation GO:0042490 14 14 0,000 0,10821345 0,14894503 ! isoprenoid biosynthetic process GO:0008299 14 14 0,000 0,10821345 0,14883387 ! hair cycle GO:0042633 14 14 0,000 0,10821345 0,14872289 GO:0022404|molting cycle process, GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042303|molting cycle, ! negative regulation of epithelial cell proliferation GO:0050680 14 14 0,000 0,10821345 0,14861206 ! immune response-activating cell surface receptor signaling pathway GO:0002429 14 14 0,000 0,10821345 0,14850141 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! response to retinoic acid GO:0032526 14 14 0,000 0,10821345 0,14839092 GO:0033189|response to vitamin A, ! multicellular organismal response to stress GO:0033555 14 14 0,000 0,10821345 0,14828059 ! lysosome organization GO:0007040 14 14 0,000 0,10821345 0,14817042 ! actin polymerization or depolymerization GO:0008154 15 14 0,000 0,10821345 0,14806042 ! D-ribose metabolic process GO:0006014 14 14 0,000 0,10821345 0,14795059 ! negative regulation of phosphorus metabolic process GO:0010563 14 14 0,000 0,10821345 0,14784091 GO:0045936|negative regulation of phosphate metabolic process, ! peptide transport GO:0015833 14 14 0,000 0,10821345 0,1477314 ! primary neural tube formation GO:0014020 15 14 0,000 0,10821345 0,14762205 ! peptide cross-linking GO:0018149 14 14 0,000 0,10821345 0,14751286 ! vitamin biosynthetic process GO:0009110 14 14 0,000 0,10821345 0,14740384 ! response to organic cyclic substance GO:0014070 15 14 0,000 0,10821345 0,14729497 ! leukotriene metabolic process GO:0006691 14 14 0,000 0,10821345 0,14718627 ! regulation of vasoconstriction GO:0019229 14 14 0,000 0,10821345 0,14707772 ! formation of primary germ layer GO:0001704 14 14 0,000 0,10821345 0,14696934 GO:0001707|mesoderm formation, ! DNA modification GO:0006304 14 14 0,000 0,10821345 0,14686111 ! collagen fibril organization GO:0030199 14 14 0,000 0,10821345 0,14675305 ! proteoglycan biosynthetic process GO:0030166 14 14 0,000 0,10821345 0,14664514 ! positive regulation of inflammatory response GO:0050729 14 14 0,000 0,10821345 0,14653739 ! group transfer coenzyme metabolic process GO:0006752 14 14 0,000 0,10821345 0,1464298 ! positive regulation of osteoblast differentiation GO:0045669 14 14 0,000 0,10821345 0,14632237 ! neuromuscular process controlling balance GO:0050885 14 14 0,000 0,10821345 0,1462151 ! aspartate family amino acid metabolic process GO:0009066 14 14 0,000 0,10821345 0,14610798 ! response to molecule of bacterial origin GO:0002237 14 14 0,000 0,10821345 0,14600102 ! negative regulation of protein polymerization GO:0032272 14 14 0,000 0,10821345 0,14589421 ! cell part morphogenesis GO:0032990 75 70 1,000 0,11075059 0,14920565 ! ribosome biogenesis GO:0042254 71 71 1,000 0,11338787 0,15264708 ! positive regulation of fibroblast proliferation GO:0048146 15 15 0,000 0,11548698 0,15535949 ! negative regulation of actin filament depolymerization GO:0030835 15 15 0,000 0,11548698 0,15524617 ! positive regulation of ossification GO:0045778 15 15 0,000 0,11548698 0,15513302 GO:0046852|positive regulation of bone remodeling, GO:0034105|positive regulation of tissue remodeling, ! negative regulation of protein complex assembly GO:0031333 15 15 0,000 0,11548698 0,15502003 ! protein amino acid O-linked glycosylation GO:0006493 15 15 0,000 0,11548698 0,15490721 ! cellular polysaccharide biosynthetic process GO:0033692 15 15 0,000 0,11548698 0,15479455 ! proteoglycan metabolic process GO:0006029 15 15 0,000 0,11548698 0,15468205 ! response to vitamin GO:0033273 15 15 0,000 0,11548698 0,15456972 ! striated muscle cell differentiation GO:0051146 16 15 0,000 0,11548698 0,15445755 ! odontogenesis of dentine-containing tooth GO:0042475 15 15 0,000 0,11548698 0,15434554 ! detection of stimulus involved in sensory perception GO:0050906 16 15 0,000 0,11548698 0,1542337 ! insulin receptor signaling pathway GO:0008286 17 15 0,000 0,11548698 0,15412202 ! ovarian follicle development GO:0001541 15 15 0,000 0,11548698 0,15401049 ! antigen processing and presentation of peptide antigen GO:0048002 15 15 0,000 0,11548698 0,15389914 ! regulation of smooth muscle contraction GO:0006940 15 15 0,000 0,11548698 0,15378794 ! deoxyribonucleotide metabolic process GO:0009262 15 15 0,000 0,11548698 0,1536769 ! complement activation, classical pathway GO:0006958 15 15 0,000 0,11548698 0,15356602 ! heme metabolic process GO:0042168 15 15 0,000 0,11548698 0,1534553 ! mesoderm morphogenesis GO:0048332 15 15 0,000 0,11548698 0,15334474 ! chromosome condensation GO:0030261 15 15 0,000 0,11548698 0,15323434 ! response to mechanical stimulus GO:0009612 15 15 0,000 0,11548698 0,1531241 ! hydrogen peroxide metabolic process GO:0042743 15 15 0,000 0,11548698 0,15301402 ! regulation of biomineral formation GO:0070167 15 15 0,000 0,11548698 0,1529041 GO:0030500|regulation of bone mineralization, ! regulation of production of molecular mediator of immune response GO:0002700 15 15 0,000 0,11548698 0,15279433 ! cyclic nucleotide biosynthetic process GO:0009190 15 15 0,000 0,11548698 0,15268472 ! cholesterol biosynthetic process GO:0006695 15 15 0,000 0,11548698 0,15257527 ! phospholipid transport GO:0015914 15 15 0,000 0,11548698 0,15246598 ! regulation of cytokine secretion GO:0050707 15 15 0,000 0,11548698 0,15235684 ! glutathione metabolic process GO:0006749 16 15 0,000 0,11548698 0,15224786 ! nicotinamide metabolic process GO:0006769 15 15 0,000 0,11548698 0,15213903 GO:0046496|nicotinamide nucleotide metabolic process, ! positive regulation of B cell activation GO:0050871 15 15 0,000 0,11548698 0,15203036 ! positive regulation of myeloid cell differentiation GO:0045639 16 15 0,000 0,11548698 0,15192184 ! cellular alkene metabolic process GO:0043449 15 15 0,000 0,11548698 0,15181348 ! protein homooligomerization GO:0051260 15 15 0,000 0,11548698 0,15170528 ! positive regulation of immune effector process GO:0002699 15 15 0,000 0,11548698 0,15159723 ! response to extracellular stimulus GO:0009991 72 72 1,000 0,11604162 0,15221687 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 16 16 0,000 0,12270224 0,16083942 ! alkaloid metabolic process GO:0009820 16 16 0,000 0,12270224 0,1607251 ! spliceosomal snRNP biogenesis GO:0000387 16 16 0,000 0,12270224 0,16061095 ! circadian rhythm GO:0007623 16 16 0,000 0,12270224 0,16049696 ! inner ear morphogenesis GO:0042472 16 16 0,000 0,12270224 0,16038313 ! positive regulation of mitosis GO:0045840 16 16 0,000 0,12270224 0,16026947 GO:0051785|positive regulation of nuclear division, ! vacuole organization GO:0007033 16 16 0,000 0,12270224 0,16015596 ! cellular response to reactive oxygen species GO:0034614 16 16 0,000 0,12270224 0,16004262 ! positive regulation of cytoskeleton organization GO:0051495 16 16 0,000 0,12270224 0,15992943 ! vesicle targeting GO:0006903 17 16 0,000 0,12270224 0,15981641 ! fatty acid beta-oxidation GO:0006635 16 16 0,000 0,12270224 0,15970355 ! triglyceride metabolic process GO:0006641 16 16 0,000 0,12270224 0,15959084 ! iron ion homeostasis GO:0055072 16 16 0,000 0,12270224 0,15947829 ! positive regulation of cell development GO:0010720 16 16 0,000 0,12270224 0,15936591 ! regulation of myeloid leukocyte differentiation GO:0002761 17 16 0,000 0,12270224 0,15925368 ! lymphocyte proliferation GO:0046651 16 16 0,000 0,12270224 0,1591416 ! regulation of systemic arterial blood pressure GO:0003073 17 16 0,000 0,12270224 0,15902969 ! cell fate specification GO:0001708 16 16 0,000 0,12270224 0,15891793 ! pentose metabolic process GO:0019321 16 16 0,000 0,12270224 0,15880633 ! fatty acid transport GO:0015908 16 16 0,000 0,12270224 0,15869489 ! positive regulation of MAPKKK cascade GO:0043410 17 16 0,000 0,12270224 0,1585836 ! regulation of microtubule cytoskeleton organization GO:0070507 16 16 0,000 0,12270224 0,15847247 ! cofactor catabolic process GO:0051187 16 16 0,000 0,12270224 0,1583615 ! ethanolamine and derivative metabolic process GO:0042439 17 16 0,000 0,12270224 0,15825068 ! polyol metabolic process GO:0019751 16 16 0,000 0,12270224 0,15814001 ! serine family amino acid metabolic process GO:0009069 16 16 0,000 0,12270224 0,1580295 ! glutamine family amino acid catabolic process GO:0009065 17 16 0,000 0,12270224 0,15791915 ! porphyrin metabolic process GO:0006778 16 16 0,000 0,12270224 0,15780895 GO:0033013|tetrapyrrole metabolic process, ! embryonic epithelial tube formation GO:0001838 17 16 0,000 0,12270224 0,1576989 GO:0001841|neural tube formation, ! positive regulation of catabolic process GO:0009896 16 16 0,000 0,12270224 0,157589 ! regulation of cell morphogenesis involved in differentiation GO:0010769 17 16 0,000 0,12270224 0,15747926 ! response to xenobiotic stimulus GO:0009410 16 16 0,000 0,12270224 0,15736967 ! ribonucleotide biosynthetic process GO:0009260 75 75 1,000 0,12409736 0,15904829 ! purine ribonucleotide metabolic process GO:0009150 75 75 1,000 0,12409736 0,15893776 ! cell morphogenesis involved in differentiation GO:0000904 82 77 1,000 0,12954242 0,16579631 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 17 17 0,000 0,12985968 0,16608701 ! regulation of actin filament depolymerization GO:0030834 17 17 0,000 0,12985968 0,16597183 ! phosphoinositide biosynthetic process GO:0046489 17 17 0,000 0,12985968 0,16585681 ! nucleotide-excision repair, DNA damage removal GO:0000718 18 17 0,000 0,12985968 0,16574196 ! leukocyte adhesion GO:0007159 17 17 0,000 0,12985968 0,16562726 ! dicarboxylic acid metabolic process GO:0043648 18 17 0,000 0,12985968 0,16551271 ! sensory perception of smell GO:0007608 17 17 0,000 0,12985968 0,16539833 ! glucose transport GO:0015758 17 17 0,000 0,12985968 0,1652841 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 17 17 0,000 0,12985968 0,16517004 ! embryonic skeletal system morphogenesis GO:0048704 17 17 0,000 0,12985968 0,16505613 ! cellular carbohydrate biosynthetic process GO:0034637 17 17 0,000 0,12985968 0,16494237 ! development of primary male sexual characteristics GO:0046546 17 17 0,000 0,12985968 0,16482878 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 17 17 0,000 0,12985968 0,16471534 ! neural crest cell development GO:0014032 19 17 0,000 0,12985968 0,16460205 GO:0014033|neural crest cell differentiation, ! immune response-activating signal transduction GO:0002757 17 17 0,000 0,12985968 0,16448892 GO:0002764|immune response-regulating signal transduction, ! cell recognition GO:0008037 18 17 0,000 0,12985968 0,16437595 ! positive regulation of protein secretion GO:0050714 17 17 0,000 0,12985968 0,16426313 ! regulation of osteoblast differentiation GO:0045667 17 17 0,000 0,12985968 0,16415047 ! pyridine nucleotide metabolic process GO:0019362 17 17 0,000 0,12985968 0,16403796 ! pigmentation GO:0043473 17 17 0,000 0,12985968 0,16392561 ! myeloid leukocyte activation GO:0002274 18 17 0,000 0,12985968 0,1638134 ! adult locomotory behavior GO:0008344 17 17 0,000 0,12985968 0,16370136 ! embryonic organ development GO:0048568 17 17 0,000 0,12985968 0,16358946 ! regulation of calcium ion transport GO:0051924 17 17 0,000 0,12985968 0,16347772 ! liver development GO:0001889 17 17 0,000 0,12985968 0,16336613 ! gene silencing GO:0016458 17 17 0,000 0,12985968 0,1632547 ! microtubule-based movement GO:0007018 82 78 1,000 0,1322861 0,16619175 ! nuclear transport GO:0051169 79 79 1,000 0,13504335 0,16954012 GO:0006913|nucleocytoplasmic transport, ! mRNA export from nucleus GO:0006406 18 18 0,000 0,13695976 0,17182902 ! regulation of cell projection organization GO:0031344 19 18 0,000 0,13695976 0,17171213 ! regulation of cellular catabolic process GO:0031329 18 18 0,000 0,13695976 0,1715954 ! icosanoid biosynthetic process GO:0046456 18 18 0,000 0,13695976 0,17147883 ! regulation of metal ion transport GO:0010959 18 18 0,000 0,13695976 0,17136241 ! membrane docking GO:0022406 18 18 0,000 0,13695976 0,17124616 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 18 18 0,000 0,13695976 0,17113006 ! mononuclear cell proliferation GO:0032943 18 18 0,000 0,13695976 0,17101411 GO:0070661|leukocyte proliferation, ! response to calcium ion GO:0051592 18 18 0,000 0,13695976 0,17089833 ! negative regulation of response to external stimulus GO:0032102 18 18 0,000 0,13695976 0,1707827 ! hexose transport GO:0008645 18 18 0,000 0,13695976 0,17066723 GO:0015749|monosaccharide transport, ! cholesterol homeostasis GO:0042632 18 18 0,000 0,13695976 0,17055191 GO:0055092|sterol homeostasis, ! striated muscle contraction GO:0006941 18 18 0,000 0,13695976 0,17043675 ! neutral lipid metabolic process GO:0006638 18 18 0,000 0,13695976 0,17032175 GO:0006639|acylglycerol metabolic process, ! ceramide metabolic process GO:0006672 18 18 0,000 0,13695976 0,1702069 GO:0046519|sphingoid metabolic process, ! telencephalon development GO:0021537 19 18 0,000 0,13695976 0,17009221 ! negative regulation of MAP kinase activity GO:0043407 18 18 0,000 0,13695976 0,16997767 ! BMP signaling pathway GO:0030509 18 18 0,000 0,13695976 0,16986328 ! regulation of microtubule-based process GO:0032886 18 18 0,000 0,13695976 0,16974905 ! symbiosis, encompassing mutualism through parasitism GO:0044403 18 18 0,000 0,13695976 0,16963497 ! establishment of vesicle localization GO:0051650 19 18 0,000 0,13695976 0,16952104 ! neuron projection development GO:0031175 85 80 1,000 0,13781378 0,17046362 ! MAPKKK cascade GO:0000165 82 81 1,000 0,14059699 0,17378957 ! activation of adenylate cyclase activity GO:0007190 19 19 0,000 0,14400293 0,1778803 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 19 19 0,000 0,14400293 0,17776115 GO:0006956|complement activation, ! glial cell differentiation GO:0010001 19 19 0,000 0,14400293 0,17764217 ! regulation of JAK-STAT cascade GO:0046425 19 19 0,000 0,14400293 0,17752335 ! feeding behavior GO:0007631 19 19 0,000 0,14400293 0,17740468 ! peroxisome organization GO:0007031 19 19 0,000 0,14400293 0,17728617 ! positive regulation of T cell proliferation GO:0042102 19 19 0,000 0,14400293 0,17716782 ! regulation of striated muscle tissue development GO:0016202 20 19 0,000 0,14400293 0,17704963 ! multicellular organismal metabolic process GO:0044236 19 19 0,000 0,14400293 0,1769316 ! metanephros development GO:0001656 19 19 0,000 0,14400293 0,17681373 ! ribonucleoside metabolic process GO:0009119 19 19 0,000 0,14400293 0,17669601 ! cellular response to oxidative stress GO:0034599 19 19 0,000 0,14400293 0,17657844 ! regulation of lymphocyte mediated immunity GO:0002706 19 19 0,000 0,14400293 0,17646104 ! positive regulation of T cell differentiation GO:0045582 19 19 0,000 0,14400293 0,17634379 ! nuclear-transcribed mRNA catabolic process GO:0000956 19 19 0,000 0,14400293 0,17622669 ! hormone biosynthetic process GO:0042446 19 19 0,000 0,14400293 0,17610976 ! biogenic amine biosynthetic process GO:0042401 20 19 0,000 0,14400293 0,17599297 ! eye morphogenesis GO:0048592 19 19 0,000 0,14400293 0,17587634 ! placenta development GO:0001890 19 19 0,000 0,14400293 0,17575987 ! response to heat GO:0009408 19 19 0,000 0,14400293 0,17564355 ! vesicle localization GO:0051648 20 19 0,000 0,14400293 0,17552738 ! ribonucleotide metabolic process GO:0009259 83 83 1,000 0,14620027 0,17808796 ! ncRNA processing GO:0034470 83 83 1,000 0,14620027 0,17797034 ! regulation of muscle development GO:0048634 21 20 0,000 0,15098964 0,18367915 ! negative regulation of cell adhesion GO:0007162 21 20 0,000 0,15098964 0,18355799 ! establishment or maintenance of cell polarity GO:0007163 21 20 0,000 0,15098964 0,18343699 ! organic ether metabolic process GO:0018904 20 20 0,000 0,15098964 0,18331615 GO:0006662|glycerol ether metabolic process, ! cytoskeleton-dependent intracellular transport GO:0030705 20 20 0,000 0,15098964 0,18319547 ! neural tube development GO:0021915 21 20 0,000 0,15098964 0,18307494 ! phagocytosis GO:0006909 21 20 0,000 0,15098964 0,18295458 ! unsaturated fatty acid biosynthetic process GO:0006636 20 20 0,000 0,15098964 0,18283437 ! protein targeting to membrane GO:0006612 22 20 0,000 0,15098964 0,18271432 ! cyclic nucleotide metabolic process GO:0009187 20 20 0,000 0,15098964 0,18259443 ! chromatin remodeling GO:0006338 20 20 0,000 0,15098964 0,1824747 ! detection of abiotic stimulus GO:0009582 21 20 0,000 0,15098964 0,18235512 ! lipid oxidation GO:0034440 20 20 0,000 0,15098964 0,1822357 GO:0019395|fatty acid oxidation, ! female gamete generation GO:0007292 20 20 0,000 0,15098964 0,18211644 ! negative regulation of neuron apoptosis GO:0043524 21 20 0,000 0,15098964 0,18199733 ! RNA modification GO:0009451 20 20 0,000 0,15098964 0,18187837 ! single fertilization GO:0007338 21 20 0,000 0,15098964 0,18175958 ! nitrogen compound biosynthetic process GO:0044271 86 85 1,000 0,1518502 0,18267618 ! positive regulation of response to stimulus GO:0048584 86 85 1,000 0,1518502 0,18255702 ! organophosphate metabolic process GO:0019637 87 86 1,000 0,15469174 0,18585194 GO:0006644|phospholipid metabolic process, ! mitotic sister chromatid segregation GO:0000070 21 21 0,000 0,15792034 0,18960729 ! mRNA catabolic process GO:0006402 21 21 0,000 0,15792034 0,18948385 ! positive regulation of adenylate cyclase activity GO:0045762 21 21 0,000 0,15792034 0,18936056 GO:0051349|positive regulation of lyase activity, GO:0031281|positive regulation of cyclase activity, ! protein amino acid lipidation GO:0006497 21 21 0,000 0,15792034 0,18923744 ! Notch signaling pathway GO:0007219 22 21 0,000 0,15792034 0,18911448 ! morphogenesis of embryonic epithelium GO:0016331 22 21 0,000 0,15792034 0,18899168 ! ear morphogenesis GO:0042471 21 21 0,000 0,15792034 0,18886904 ! organic anion transport GO:0015711 21 21 0,000 0,15792034 0,18874655 ! cholesterol transport GO:0030301 21 21 0,000 0,15792034 0,18862423 GO:0015918|sterol transport, ! spliceosome assembly GO:0000245 22 21 0,000 0,15792034 0,18850206 ! regulation of Rab protein signal transduction GO:0032483 21 21 0,000 0,15792034 0,18838006 GO:0032313|regulation of Rab GTPase activity, ! regulation of leukocyte mediated immunity GO:0002703 21 21 0,000 0,15792034 0,18825821 ! regulation of multicellular organism growth GO:0040014 21 21 0,000 0,15792034 0,18813651 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 21 21 0,000 0,15792034 0,18801498 ! regulation of proteolysis GO:0030162 21 21 0,000 0,15792034 0,1878936 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 21 21 0,000 0,15792034 0,18777238 ! cellular response to insulin stimulus GO:0032869 23 21 0,000 0,15792034 0,18765131 ! purine nucleotide biosynthetic process GO:0006164 88 88 1,000 0,16040622 0,19048239 ! RNA export from nucleus GO:0006405 22 22 0,000 0,16479546 0,1955686 ! positive regulation of DNA metabolic process GO:0051054 23 22 0,000 0,16479546 0,19544275 ! sister chromatid segregation GO:0000819 22 22 0,000 0,16479546 0,19531707 ! cellular amide metabolic process GO:0043603 22 22 0,000 0,16479546 0,19519154 ! regulation of ion transport GO:0043269 22 22 0,000 0,16479546 0,19506618 ! odontogenesis GO:0042476 22 22 0,000 0,16479546 0,19494097 ! positive regulation of lymphocyte proliferation GO:0050671 22 22 0,000 0,16479546 0,19481593 GO:0032946|positive regulation of mononuclear cell proliferation, GO:0070665|positive regulation of leukocyte proliferation, GO:0070668|positive regulation of mast cell proliferation, ! hormone-mediated signaling GO:0009755 22 22 0,000 0,16479546 0,19469105 ! embryonic skeletal system development GO:0048706 22 22 0,000 0,16479546 0,19456633 ! ovulation cycle process GO:0022602 22 22 0,000 0,16479546 0,19444176 ! spindle organization GO:0007051 22 22 0,000 0,16479546 0,19431736 ! cell chemotaxis GO:0060326 23 22 0,000 0,16479546 0,19419312 GO:0030595|leukocyte chemotaxis, ! respiratory gaseous exchange GO:0007585 22 22 0,000 0,16479546 0,19406903 ! erythrocyte differentiation GO:0030218 23 22 0,000 0,16479546 0,19394511 ! sterol biosynthetic process GO:0016126 22 22 0,000 0,16479546 0,19382134 ! biopolymer methylation GO:0043414 22 22 0,000 0,16479546 0,19369773 GO:0032259|methylation, ! regulation of adaptive immune response GO:0002819 22 22 0,000 0,16479546 0,19357427 ! detection of external stimulus GO:0009581 23 22 0,000 0,16479546 0,19345098 ! neuron migration GO:0001764 22 22 0,000 0,16479546 0,19332784 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 22 22 0,000 0,16479546 0,19320486 ! positive regulation of lymphocyte differentiation GO:0045621 22 22 0,000 0,16479546 0,19308203 ! fatty acid catabolic process GO:0009062 23 22 0,000 0,16479546 0,19295936 ! aerobic respiration GO:0009060 22 22 0,000 0,16479546 0,19283685 ! cytokine production GO:0001816 22 22 0,000 0,16479546 0,19271449 ! cytokinesis GO:0000910 23 22 0,000 0,16479546 0,19259229 ! pyrimidine nucleotide metabolic process GO:0006220 22 22 0,000 0,16479546 0,19247024 ! response to hydrogen peroxide GO:0042542 24 23 0,000 0,17161545 0,20030859 ! viral infectious cycle GO:0019058 23 23 0,000 0,17161545 0,20018182 ! regulation of hormone secretion GO:0046883 23 23 0,000 0,17161545 0,2000552 ! response to estrogen stimulus GO:0043627 23 23 0,000 0,17161545 0,19992874 ! negative regulation of protein complex disassembly GO:0043242 23 23 0,000 0,17161545 0,19980244 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 23 23 0,000 0,17161545 0,19967631 ! regulation of ARF protein signal transduction GO:0032012 23 23 0,000 0,17161545 0,19955033 ! endocrine system development GO:0035270 23 23 0,000 0,17161545 0,19942451 ! lipoprotein biosynthetic process GO:0042158 23 23 0,000 0,17161545 0,19929885 ! positive regulation of growth GO:0045927 23 23 0,000 0,17161545 0,19917334 ! female gonad development GO:0008585 23 23 0,000 0,17161545 0,199048 ! lipid homeostasis GO:0055088 23 23 0,000 0,17161545 0,19892281 ! Rho protein signal transduction GO:0007266 24 23 0,000 0,17161545 0,19879778 ! positive regulation of immune system process GO:0002684 92 92 1,000 0,17195107 0,19906144 ! tissue morphogenesis GO:0048729 94 93 1,000 0,17485946 0,20230131 ! gliogenesis GO:0042063 24 24 0,000 0,17838073 0,20624572 ! cellular amino acid biosynthetic process GO:0008652 24 24 0,000 0,17838073 0,20611642 ! heterocycle biosynthetic process GO:0018130 24 24 0,000 0,17838073 0,20598727 ! nucleotide catabolic process GO:0009166 24 24 0,000 0,17838073 0,20585829 ! erythrocyte homeostasis GO:0034101 25 24 0,000 0,17838073 0,20572946 ! ovulation cycle GO:0042698 24 24 0,000 0,17838073 0,2056008 ! fertilization GO:0009566 25 24 0,000 0,17838073 0,2054723 ! oxidoreduction coenzyme metabolic process GO:0006733 24 24 0,000 0,17838073 0,20534396 ! epithelial tube morphogenesis GO:0060562 25 24 0,000 0,17838073 0,20521578 ! regulation of actin filament polymerization GO:0030833 25 25 0,000 0,18509174 0,21280354 ! negative regulation of secretion GO:0051048 26 25 0,000 0,18509174 0,21267087 ! protein amino acid N-linked glycosylation GO:0006487 25 25 0,000 0,18509174 0,21253836 ! sensory perception of chemical stimulus GO:0007606 25 25 0,000 0,18509174 0,21240602 ! development of primary female sexual characteristics GO:0046545 25 25 0,000 0,18509174 0,21227385 GO:0046660|female sex differentiation, ! polysaccharide biosynthetic process GO:0000271 25 25 0,000 0,18509174 0,21214184 ! excretion GO:0007588 25 25 0,000 0,18509174 0,21200999 ! generation of a signal involved in cell-cell signaling GO:0003001 27 25 0,000 0,18509174 0,21187831 ! gastrulation GO:0007369 25 25 0,000 0,18509174 0,21174679 ! heart morphogenesis GO:0003007 25 25 0,000 0,18509174 0,21161543 ! icosanoid metabolic process GO:0006690 25 25 0,000 0,18509174 0,21148424 ! JAK-STAT cascade GO:0007259 26 25 0,000 0,18509174 0,2113532 ! positive regulation of cytokine production GO:0001819 25 25 0,000 0,18509174 0,21122234 ! blood circulation GO:0008015 99 98 1,000 0,18951846 0,21614017 GO:0003013|circulatory system process, ! regulation of system process GO:0044057 98 98 1,000 0,18951846 0,21600651 ! positive regulation of defense response GO:0031349 26 26 0,000 0,1917489 0,21841361 ! transforming growth factor beta receptor signaling pathway GO:0007179 26 26 0,000 0,1917489 0,21827871 ! negative regulation of cell migration GO:0030336 26 26 0,000 0,1917489 0,21814397 ! cellular defense response GO:0006968 26 26 0,000 0,1917489 0,21800939 ! positive regulation of cytokine biosynthetic process GO:0042108 26 26 0,000 0,1917489 0,21787499 ! regulation of protein secretion GO:0050708 26 26 0,000 0,1917489 0,21774074 ! germ cell development GO:0007281 27 26 0,000 0,1917489 0,21760667 ! regulation of blood vessel size GO:0050880 27 26 0,000 0,1917489 0,21747275 GO:0035150|regulation of tube size, ! response to insulin stimulus GO:0032868 28 26 0,000 0,1917489 0,21733901 ! anti-apoptosis GO:0006916 100 99 1,000 0,1924715 0,21802395 ! chloride transport GO:0006821 27 27 0,000 0,19835265 0,22454787 ! regulation of neurotransmitter levels GO:0001505 31 27 0,000 0,19835265 0,22441002 ! monocarboxylic acid transport GO:0015718 27 27 0,000 0,19835265 0,22427235 ! peptide metabolic process GO:0006518 29 27 0,000 0,19835265 0,22413484 ! mesenchymal cell development GO:0014031 29 27 0,000 0,19835265 0,2239975 GO:0060485|mesenchyme development, GO:0048762|mesenchymal cell differentiation, ! inner ear development GO:0048839 27 27 0,000 0,19835265 0,22386033 ! defense response to bacterium GO:0042742 27 27 0,000 0,19835265 0,22372333 ! isoprenoid metabolic process GO:0006720 27 27 0,000 0,19835265 0,2235865 ! cell growth GO:0016049 27 27 0,000 0,19835265 0,22344983 ! tRNA aminoacylation for protein translation GO:0006418 28 28 0,000 0,20490339 0,23068842 GO:0043038|amino acid activation, GO:0043039|tRNA aminoacylation, ! neuromuscular process GO:0050905 28 28 0,000 0,20490339 0,23054759 ! carbohydrate transport GO:0008643 28 28 0,000 0,20490339 0,23040692 ! regulation of muscle contraction GO:0006937 28 28 0,000 0,20490339 0,23026643 ! unsaturated fatty acid metabolic process GO:0033559 28 28 0,000 0,20490339 0,23012611 ! sulfur compound biosynthetic process GO:0044272 28 28 0,000 0,20490339 0,22998596 ! developmental growth GO:0048589 28 28 0,000 0,20490339 0,22984598 ! glycerophospholipid biosynthetic process GO:0046474 30 29 0,000 0,21140155 0,23699091 ! viral reproductive process GO:0022415 29 29 0,000 0,21140155 0,23684685 ! leukocyte migration GO:0050900 30 29 0,000 0,21140155 0,23670295 ! antigen processing and presentation GO:0019882 29 29 0,000 0,21140155 0,23655924 ! tRNA processing GO:0008033 29 29 0,000 0,21140155 0,23641569 ! regulation of gene expression, epigenetic GO:0040029 29 29 0,000 0,21140155 0,23627232 ! adult behavior GO:0030534 30 29 0,000 0,21140155 0,23612913 ! regulation of protein polymerization GO:0032271 29 29 0,000 0,21140155 0,23598611 ! transition metal ion transport GO:0000041 31 30 0,000 0,21784755 0,24303452 ! RNA catabolic process GO:0006401 30 30 0,000 0,21784755 0,2428875 ! response to reactive oxygen species GO:0000302 31 30 0,000 0,21784755 0,24274065 ! ER to Golgi vesicle-mediated transport GO:0006888 30 30 0,000 0,21784755 0,24259398 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 30 30 0,000 0,21784755 0,24244748 ! regulation of protein complex disassembly GO:0043244 30 30 0,000 0,21784755 0,24230117 ! positive regulation of protein amino acid phosphorylation GO:0001934 30 30 0,000 0,21784755 0,24215502 ! response to temperature stimulus GO:0009266 30 30 0,000 0,21784755 0,24200906 ! regulation of ossification GO:0030278 30 30 0,000 0,21784755 0,24186327 ! regulation of inflammatory response GO:0050727 30 30 0,000 0,21784755 0,24171766 ! water-soluble vitamin metabolic process GO:0006767 30 30 0,000 0,21784755 0,24157222 ! cellular amino acid derivative biosynthetic process GO:0042398 31 30 0,000 0,21784755 0,24142696 ! establishment of organelle localization GO:0051656 31 30 0,000 0,21784755 0,24128187 ! regulation of translational initiation GO:0006446 31 31 0,000 0,22424179 0,24821478 ! membrane fusion GO:0006944 31 31 0,000 0,22424179 0,24806579 ! negative regulation of cytoskeleton organization GO:0051494 32 31 0,000 0,22424179 0,24791698 ! lipoprotein metabolic process GO:0042157 31 31 0,000 0,22424179 0,24776835 ! ion transmembrane transport GO:0034220 31 31 0,000 0,22424179 0,2476199 GO:0015985|energy coupled proton transport, down electrochemical gradient, GO:0015986|ATP synthesis coupled proton transport, ! glycerolipid biosynthetic process GO:0045017 32 31 0,000 0,22424179 0,24747163 ! digestion GO:0007586 31 31 0,000 0,22424179 0,24732353 ! nucleoside metabolic process GO:0009116 31 31 0,000 0,22424179 0,24717561 ! regulation of heart contraction GO:0008016 31 31 0,000 0,22424179 0,24702786 ! sphingolipid metabolic process GO:0006665 31 31 0,000 0,22424179 0,2468803 ! camera-type eye development GO:0043010 31 31 0,000 0,22424179 0,2467329 ! extracellular matrix organization GO:0030198 31 31 0,000 0,22424179 0,24658569 ! ribonucleoprotein complex assembly GO:0022618 32 31 0,000 0,22424179 0,24643865 ! regulation of myeloid cell differentiation GO:0045637 32 31 0,000 0,22424179 0,24629178 ! cell redox homeostasis GO:0045454 32 32 0,000 0,23058468 0,25310754 ! lipid modification GO:0030258 32 32 0,000 0,23058468 0,25295688 ! glycosaminoglycan metabolic process GO:0030203 34 32 0,000 0,23058468 0,2528064 ! nuclear export GO:0051168 32 32 0,000 0,23058468 0,2526561 ! kidney development GO:0001822 32 32 0,000 0,23058468 0,25250598 ! protein maturation by peptide bond cleavage GO:0051605 32 32 0,000 0,23058468 0,25235603 ! amino acid transport GO:0006865 33 33 0,000 0,23687663 0,2590882 ! activation of protein kinase activity GO:0032147 35 33 0,000 0,23687663 0,25893453 ! regulation of protein complex assembly GO:0043254 33 33 0,000 0,23687663 0,25878104 ! membrane lipid metabolic process GO:0006643 33 33 0,000 0,23687663 0,25862774 ! regulation of actin polymerization or depolymerization GO:0008064 33 33 0,000 0,23687663 0,25847461 ! regulation of neuron differentiation GO:0045664 34 33 0,000 0,23687663 0,25832167 ! response to metal ion GO:0010038 34 34 0,000 0,24311803 0,26497134 ! ear development GO:0043583 34 34 0,000 0,24311803 0,26481474 ! muscle cell differentiation GO:0042692 35 34 0,000 0,24311803 0,26465832 ! coenzyme biosynthetic process GO:0009108 34 34 0,000 0,24311803 0,26450209 ! regulation of lipid metabolic process GO:0019216 34 34 0,000 0,24311803 0,26434604 ! response to peptide hormone stimulus GO:0043434 36 34 0,000 0,24311803 0,26419017 ! negative regulation of response to stimulus GO:0048585 34 34 0,000 0,24311803 0,26403449 ! viral reproduction GO:0016032 34 34 0,000 0,24311803 0,26387899 ! detection of stimulus GO:0051606 36 34 0,000 0,24311803 0,26372368 ! acute inflammatory response GO:0002526 35 35 0,000 0,2493093 0,27028061 ! regulation of cytokine biosynthetic process GO:0042035 35 35 0,000 0,2493093 0,27012171 ! multicellular organism reproduction GO:0032504 36 35 0,000 0,2493093 0,269963 GO:0048609|reproductive process in a multicellular organism, ! inorganic anion transport GO:0015698 35 35 0,000 0,2493093 0,26980448 ! response to steroid hormone stimulus GO:0048545 35 35 0,000 0,2493093 0,26964615 ! regulation of immune effector process GO:0002697 35 35 0,000 0,2493093 0,269488 ! hydrogen transport GO:0006818 36 36 0,000 0,25545081 0,27596474 GO:0015992|proton transport, ! response to inorganic substance GO:0010035 36 36 0,000 0,25545081 0,27580307 ! aminoglycan metabolic process GO:0006022 38 36 0,000 0,25545081 0,2756416 ! oxygen and reactive oxygen species metabolic process GO:0006800 37 36 0,000 0,25545081 0,27548031 ! regulation of mitosis GO:0007088 37 36 0,000 0,25545081 0,27531921 GO:0051783|regulation of nuclear division, ! embryonic limb morphogenesis GO:0030326 36 36 0,000 0,25545081 0,2751583 GO:0035113|embryonic appendage morphogenesis, ! female pregnancy GO:0007565 37 36 0,000 0,25545081 0,27499757 ! RNA elongation from RNA polymerase II promoter GO:0006368 36 36 0,000 0,25545081 0,27483704 ! positive regulation of organelle organization GO:0010638 36 36 0,000 0,25545081 0,27467669 ! heterocycle catabolic process GO:0046700 36 36 0,000 0,25545081 0,27451653 ! activation of immune response GO:0002253 36 36 0,000 0,25545081 0,27435655 ! eye development GO:0001654 37 37 0,000 0,26154297 0,28073599 ! ATP synthesis coupled electron transport GO:0042773 37 37 0,000 0,26154297 0,28057258 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! cellular amino acid catabolic process GO:0009063 38 37 0,000 0,26154297 0,28040937 ! regulation of Rho protein signal transduction GO:0035023 37 37 0,000 0,26154297 0,28024634 ! positive regulation of secretion GO:0051047 39 38 0,000 0,26758617 0,28655509 ! neurotransmitter transport GO:0006836 40 38 0,000 0,26758617 0,28638868 ! cellular hormone metabolic process GO:0034754 39 38 0,000 0,26758617 0,28622247 ! exocytosis GO:0006887 40 38 0,000 0,26758617 0,28605645 ! chromosome segregation GO:0007059 38 38 0,000 0,26758617 0,28589062 ! RNA elongation GO:0006354 38 38 0,000 0,26758617 0,28572498 ! positive regulation of protein modification process GO:0031401 39 39 0,000 0,27358079 0,2919568 ! response to unfolded protein GO:0006986 39 39 0,000 0,27358079 0,29178784 ! fatty acid biosynthetic process GO:0006633 39 39 0,000 0,27358079 0,29161908 ! intracellular protein transmembrane transport GO:0065002 39 39 0,000 0,27358079 0,29145052 ! positive regulation of T cell activation GO:0050870 39 39 0,000 0,27358079 0,29128214 ! limb development GO:0060173 39 39 0,000 0,27358079 0,29111397 GO:0048736|appendage development, GO:0035107|appendage morphogenesis, ! myeloid cell differentiation GO:0030099 42 40 0,000 0,27952721 0,29726985 ! organelle localization GO:0051640 41 40 0,000 0,27952721 0,29709841 ! amine catabolic process GO:0009310 42 41 0,000 0,28542582 0,30319296 ! elevation of cytosolic calcium ion concentration GO:0007204 41 41 0,000 0,28542582 0,30301831 ! phospholipid biosynthetic process GO:0008654 42 41 0,000 0,28542582 0,30284386 ! regulation of Ras GTPase activity GO:0032318 41 41 0,000 0,28542582 0,30266961 ! respiratory electron transport chain GO:0022904 43 42 0,000 0,29127699 0,30869666 ! cytosolic calcium ion homeostasis GO:0051480 42 42 0,000 0,29127699 0,30851925 ! protein ubiquitination GO:0016567 43 42 0,000 0,29127699 0,30834204 ! response to protein stimulus GO:0051789 42 42 0,000 0,29127699 0,30816503 ! forebrain development GO:0030900 43 42 0,000 0,29127699 0,30798823 ! one-carbon metabolic process GO:0006730 42 42 0,000 0,29127699 0,30781163 ! humoral immune response GO:0006959 44 44 0,000 0,30283851 0,31984606 ! mRNA transport GO:0051028 44 44 0,000 0,30283851 0,31966287 ! negative regulation of organelle organization GO:0010639 45 44 0,000 0,30283851 0,3194799 ! vitamin metabolic process GO:0006766 44 44 0,000 0,30283851 0,31929713 ! positive regulation of lymphocyte activation GO:0051251 44 44 0,000 0,30283851 0,31911457 ! amine biosynthetic process GO:0009309 46 45 0,000 0,30854961 0,32494682 ! steroid biosynthetic process GO:0006694 46 45 0,000 0,30854961 0,32476124 ! protein processing GO:0016485 45 45 0,000 0,30854961 0,32457587 ! transcription initiation from RNA polymerase II promoter GO:0006367 46 46 0,000 0,31421475 0,33034671 ! cellular response to hormone stimulus GO:0032870 48 46 0,000 0,31421475 0,33015837 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 47 47 0,000 0,31983429 0,33587157 ! regulation of blood pressure GO:0008217 48 47 0,000 0,31983429 0,3356803 ! amine transport GO:0015837 47 47 0,000 0,31983429 0,33548924 ! rhythmic process GO:0048511 47 47 0,000 0,31983429 0,33529841 ! calcium ion transport GO:0006816 48 48 0,000 0,3254086 0,3409483 ! regulation of cell cycle process GO:0010564 50 48 0,000 0,3254086 0,34075458 ! cellular lipid catabolic process GO:0044242 50 49 0,000 0,33093804 0,34634799 ! divalent metal ion transport GO:0070838 49 49 0,000 0,33093804 0,34615143 ! response to nutrient GO:0007584 49 49 0,000 0,33093804 0,34595508 ! response to bacterium GO:0009617 50 49 0,000 0,33093804 0,34575896 ! cofactor biosynthetic process GO:0051188 49 49 0,000 0,33093804 0,34556307 ! positive regulation of cell activation GO:0050867 49 49 0,000 0,33093804 0,34536739 GO:0002696|positive regulation of leukocyte activation, ! regulation of defense response GO:0031347 50 50 0,000 0,33642296 0,35089276 ! RNA transport GO:0050658 50 50 0,000 0,33642296 0,3506943 GO:0050657|nucleic acid transport, GO:0051236|establishment of RNA localization, ! nitrogen compound catabolic process GO:0044270 51 50 0,000 0,33642296 0,35049605 ! transcription initiation GO:0006352 50 50 0,000 0,33642296 0,35029803 ! biogenic amine metabolic process GO:0006576 52 51 0,000 0,34186371 0,35576218 ! protein modification by small protein conjugation GO:0032446 52 51 0,000 0,34186371 0,35556141 ! positive regulation of immune response GO:0050778 51 51 0,000 0,34186371 0,35536087 ! ATP biosynthetic process GO:0006754 51 51 0,000 0,34186371 0,35516055 ! protein maturation GO:0051604 51 51 0,000 0,34186371 0,35496046 ! RNA localization GO:0006403 52 52 0,000 0,34726064 0,36036112 ! cholesterol metabolic process GO:0008203 52 52 0,000 0,34726064 0,36015833 ! regulation of GTPase activity GO:0043087 53 52 0,000 0,34726064 0,35995577 ! tRNA metabolic process GO:0006399 53 53 0,000 0,35261409 0,36529948 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 53 53 0,000 0,35261409 0,36509426 ! protein amino acid dephosphorylation GO:0006470 55 54 0,000 0,35792442 0,37038445 ! response to virus GO:0009615 54 54 0,000 0,35792442 0,37017661 ! sulfur metabolic process GO:0006790 55 54 0,000 0,35792442 0,36996899 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 55 55 0,000 0,36319196 0,37520336 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! microtubule cytoskeleton organization GO:0000226 55 55 0,000 0,36319196 0,37499316 ! protein modification by small protein conjugation or removal GO:0070647 56 55 0,000 0,36319196 0,3747832 ! ribonucleoside triphosphate biosynthetic process GO:0009201 56 56 0,000 0,36841706 0,3799623 ! ATP metabolic process GO:0046034 57 57 0,000 0,37360003 0,3850922 ! nucleoside triphosphate biosynthetic process GO:0009142 57 57 0,000 0,37360003 0,38487695 ! innate immune response GO:0045087 58 58 0,000 0,37874123 0,38995536 ! dephosphorylation GO:0016311 60 59 0,000 0,38384098 0,39498544 ! carboxylic acid transport GO:0046942 59 59 0,000 0,38384098 0,39476503 GO:0015849|organic acid transport, ! sterol metabolic process GO:0016125 59 59 0,000 0,38384098 0,39454486 ! potassium ion transport GO:0006813 60 60 0,000 0,38889961 0,39952173 ! negative regulation of cellular protein metabolic process GO:0032269 60 60 0,000 0,38889961 0,39929915 ! cellular respiration GO:0045333 62 61 0,000 0,39391744 0,40422597 ! carboxylic acid catabolic process GO:0046395 63 61 0,000 0,39391744 0,40400103 GO:0016054|organic acid catabolic process, ! positive regulation of cellular protein metabolic process GO:0032270 61 61 0,000 0,39391744 0,40377633 ! lipid transport GO:0006869 62 62 0,000 0,3988948 0,40865099 ! purine ribonucleoside triphosphate metabolic process GO:0009205 62 62 0,000 0,3988948 0,40842396 ! regulation of cellular component biogenesis GO:0044087 63 62 0,000 0,3988948 0,40819718 ! di-, tri-valent inorganic cation transport GO:0015674 63 62 0,000 0,3988948 0,40797066 ! regulation of secretion GO:0051046 65 63 0,000 0,40383201 0,41279113 ! negative regulation of cellular component organization GO:0051129 65 63 0,000 0,40383201 0,41256231 ! ribonucleoside triphosphate metabolic process GO:0009199 63 63 0,000 0,40383201 0,41233374 ! purine nucleoside triphosphate metabolic process GO:0009144 63 63 0,000 0,40383201 0,41210543 ! positive regulation of protein metabolic process GO:0051247 64 64 0,000 0,40872939 0,41687231 ! protein amino acid glycosylation GO:0006486 66 66 0,000 0,4184059 0,42650557 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! nucleoside triphosphate metabolic process GO:0009141 66 66 0,000 0,4184059 0,4262698 ! muscle contraction GO:0006936 67 67 0,000 0,42318566 0,4309012 ! Ras protein signal transduction GO:0007265 69 67 0,000 0,42318566 0,43066326 ! regulation of translation GO:0006417 69 69 0,000 0,43262972 0,44003122 ! growth GO:0040007 70 70 0,000 0,43729463 0,44453062 ! carboxylic acid biosynthetic process GO:0046394 70 70 0,000 0,43729463 0,44428556 GO:0016053|organic acid biosynthetic process, ! translational elongation GO:0006414 71 71 0,000 0,44192187 0,4487394 ! oxidative phosphorylation GO:0006119 71 71 0,000 0,44192187 0,4484923 ! calcium ion homeostasis GO:0055074 71 71 0,000 0,44192187 0,44824547 GO:0006874|cellular calcium ion homeostasis, ! secretion by cell GO:0032940 75 72 0,000 0,44651174 0,45265189 ! muscle system process GO:0003012 72 72 0,000 0,44651174 0,45240304 ! sensory organ development GO:0007423 72 72 0,000 0,44651174 0,45215447 ! regulation of cytokine production GO:0001817 72 72 0,000 0,44651174 0,45190617 ! electron transport chain GO:0022900 75 74 0,000 0,45558051 0,46083144 ! coenzyme metabolic process GO:0006732 75 74 0,000 0,45558051 0,46057866 ! response to oxidative stress GO:0006979 76 75 0,000 0,46006002 0,46485231 ! positive regulation of multicellular organismal process GO:0051240 76 76 0,000 0,46450331 0,46908472 ! cellular metal ion homeostasis GO:0006875 77 77 0,000 0,46891069 0,47327624 ! metal ion homeostasis GO:0055065 78 78 0,000 0,47328244 0,47742723 ! regulation of immune response GO:0050776 78 78 0,000 0,47328244 0,47716605 ! glycoprotein biosynthetic process GO:0009101 80 80 0,000 0,48192017 0,48560901 ! lipid catabolic process GO:0016042 82 81 0,000 0,48618671 0,4896405 ! cellular amino acid derivative metabolic process GO:0006575 87 84 0,000 0,49878034 0,50204925 ! positive regulation of cell differentiation GO:0045597 87 85 0,000 0,50291046 0,50593012 ! male gamete generation GO:0048232 90 88 0,000 0,51510131 0,51791146 GO:0007283|spermatogenesis, ! cellular di-, tri-valent inorganic cation homeostasis GO:0030005 89 89 0,000 0,51909929 0,52164667 ! regulation of Ras protein signal transduction GO:0046578 90 90 0,000 0,5230649 0,52534529 ! brain development GO:0007420 91 90 0,000 0,5230649 0,52505916 ! di-, tri-valent inorganic cation homeostasis GO:0055066 91 91 0,000 0,52699839 0,52871966 ! visual perception GO:0007601 93 92 0,000 0,5309 0,53234424 GO:0050953|sensory perception of light stimulus, ! fatty acid metabolic process GO:0006631 93 92 0,000 0,5309 0,53205476 ! cofactor metabolic process GO:0051186 95 94 0,000 0,53860865 0,53948682 ! glycoprotein metabolic process GO:0009100 99 98 0,000 0,55365458 0,55425605 ! response to hormone stimulus GO:0009725 102 100 0,000 0,56099577 0,56130033 ! response to other organism GO:0051707 101 100 0,000 0,56099577 0,56099577