pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6815-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 8,000 5,894E-09 1,418E-05 ! regulation of ligase activity GO:0051340 142 84 8,000 1,022E-08 1,229E-05 ! negative regulation of ligase activity GO:0051352 112 68 7,000 3,255E-08 2,611E-05 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 7,000 3,255E-08 1,958E-05 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 7,000 3,66E-08 1,761E-05 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 7,000 5,143E-08 2,062E-05 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 7,000 5,143E-08 1,768E-05 ! fructose metabolic process GO:0006000 25 16 4,000 7,593E-08 2,284E-05 ! positive regulation of ligase activity GO:0051351 124 77 7,000 8,766E-08 2,344E-05 ! response to UV GO:0009411 104 53 6,000 1,065E-07 2,562E-05 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 7,000 3,844E-07 8,409E-05 GO:0010498|proteasomal protein catabolic process, ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 3,000 5,322E-07 1,067E-04 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 6,000 5,515E-07 1,021E-04 ! regulation of B cell proliferation GO:0030888 20 12 3,000 1,24E-06 2,131E-04 ! negative regulation of mast cell proliferation GO:0070667 23 12 3,000 1,24E-06 1,989E-04 GO:0042130|negative regulation of T cell proliferation, ! nucleosome assembly GO:0006334 122 85 6,000 2,805E-06 4,218E-04 ! chromatin assembly GO:0031497 124 86 6,000 3,035E-06 4,296E-04 ! polyol catabolic process GO:0046174 7 5 2,000 3,65E-06 4,879E-04 GO:0019405|alditol catabolic process, ! protein-DNA complex assembly GO:0065004 130 90 6,000 4,119E-06 5,216E-04 ! negative regulation of leukocyte proliferation GO:0070664 31 16 3,000 4,458E-06 5,363E-04 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! nucleosome organization GO:0034728 138 92 6,000 4,771E-06 5,466E-04 ! negative regulation of DNA binding GO:0043392 68 37 4,000 6,699E-06 7,326E-04 ! negative regulation of B cell activation GO:0050869 13 6 2,000 7,262E-06 7,596E-04 ! negative regulation of binding GO:0051100 72 40 4,000 9,937E-06 9,961E-04 ! apoptotic mitochondrial changes GO:0008637 41 20 3,000 1,16E-05 1,117E-03 ! negative regulation of T cell activation GO:0050868 40 20 3,000 1,16E-05 1,074E-03 ! regulation of helicase activity GO:0051095 15 7 2,000 1,264E-05 1,126E-03 ! N-terminal protein amino acid acetylation GO:0006474 13 7 2,000 1,264E-05 1,086E-03 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 2,000 1,264E-05 1,049E-03 ! calcium-independent cell-cell adhesion GO:0016338 30 22 3,000 1,732E-05 1,389E-03 ! induction of apoptosis by intracellular signals GO:0008629 93 45 4,000 1,792E-05 1,391E-03 ! regulation of gene-specific transcription GO:0032583 96 46 4,000 1,999E-05 1,503E-03 ! ER overload response GO:0006983 12 8 2,000 2,012E-05 1,467E-03 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 2,000 2,012E-05 1,424E-03 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 2,000 2,012E-05 1,383E-03 ! regulation of mast cell proliferation GO:0070666 81 48 4,000 2,467E-05 1,649E-03 ! regulation of leukocyte proliferation GO:0070663 88 51 4,000 3,326E-05 2,163E-03 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 53 27 3,000 4,04E-05 2,558E-03 ! regulation of DNA binding GO:0051101 155 88 5,000 4,326E-05 2,669E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 4,000 5,725E-05 3,443E-03 ! peptide or protein amino-terminal blocking GO:0018409 21 11 2,000 5,833E-05 3,423E-03 ! cell junction assembly GO:0034329 78 30 3,000 6,202E-05 3,553E-03 ! negative regulation of leukocyte activation GO:0002695 56 30 3,000 6,202E-05 3,47E-03 ! regulation of B cell activation GO:0050864 50 30 3,000 6,202E-05 3,391E-03 ! negative regulation of transcription regulator activity GO:0090048 58 31 3,000 7,081E-05 3,786E-03 GO:0043433|negative regulation of transcription factor activity, ! focal adhesion formation GO:0048041 35 12 2,000 7,736E-05 4,046E-03 ! histone acetylation GO:0016573 26 12 2,000 7,736E-05 3,96E-03 ! peptidyl-lysine modification GO:0018205 21 12 2,000 7,736E-05 3,878E-03 ! hexose biosynthetic process GO:0019319 48 32 3,000 8,047E-05 3,951E-03 ! positive regulation of gene-specific transcription GO:0043193 65 33 3,000 9,105E-05 4,381E-03 ! cellular carbohydrate catabolic process GO:0044275 15 13 2,000 1E-04 4,719E-03 ! cytoplasmic sequestering of protein GO:0051220 24 13 2,000 1E-04 4,629E-03 ! lung development GO:0030324 144 67 4,000 1,246E-04 5,654E-03 ! N-terminal protein amino acid modification GO:0031365 27 14 2,000 1,266E-04 5,643E-03 ! release of cytochrome c from mitochondria GO:0001836 30 14 2,000 1,266E-04 5,54E-03 ! cell junction organization GO:0034330 86 36 3,000 1,289E-04 5,537E-03 ! maintenance of protein location in cell GO:0032507 86 36 3,000 1,289E-04 5,44E-03 ! monosaccharide biosynthetic process GO:0046364 52 36 3,000 1,289E-04 5,346E-03 ! negative regulation of cell activation GO:0050866 65 36 3,000 1,289E-04 5,255E-03 ! respiratory tube development GO:0030323 150 70 4,000 1,534E-04 6,151E-03 ! respiratory system development GO:0060541 153 72 4,000 1,753E-04 6,913E-03 ! maintenance of protein location GO:0045185 91 40 3,000 1,955E-04 7,586E-03 ! regulation of transcription factor activity GO:0051090 126 74 4,000 1,995E-04 7,617E-03 GO:0090046|regulation of transcription regulator activity, ! regulation of T cell proliferation GO:0042129 71 41 3,000 2,154E-04 8,098E-03 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 2,000 2,328E-04 8,618E-03 ! alcohol biosynthetic process GO:0046165 59 42 3,000 2,367E-04 8,63E-03 ! regulation of intracellular protein transport GO:0033157 80 42 3,000 2,367E-04 8,501E-03 ! epithelial cell differentiation GO:0030855 79 43 3,000 2,596E-04 9,184E-03 ! energy reserve metabolic process GO:0006112 74 43 3,000 2,596E-04 9,051E-03 ! neural tube development GO:0021915 77 43 3,000 2,596E-04 8,921E-03 ! glutamine metabolic process GO:0006541 29 18 2,000 2,779E-04 9,418E-03 ! cell-substrate junction assembly GO:0007044 54 18 2,000 2,779E-04 9,287E-03 ! maintenance of location in cell GO:0051651 97 44 3,000 2,839E-04 9,357E-03 ! actin filament bundle formation GO:0051017 42 19 2,000 3,283E-04 0,0106735 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 3,000 3,375E-04 0,01082593 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 3,000 3,375E-04 0,01068349 ! protein amino acid acetylation GO:0006473 39 20 2,000 3,842E-04 0,01200385 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 2,000 3,842E-04 0,01184995 ! tube morphogenesis GO:0035239 176 86 4,000 4,021E-04 0,01224686 ! phosphatidylinositol metabolic process GO:0046488 36 21 2,000 4,458E-04 0,01340789 ! cell structure disassembly during apoptosis GO:0006921 30 21 2,000 4,458E-04 0,01324236 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 2,000 4,458E-04 0,01308087 ! negative regulation of immune system process GO:0002683 95 50 3,000 4,657E-04 0,01349886 ! chromatin remodeling GO:0006338 109 51 3,000 5,025E-04 0,01439224 ! positive regulation of helicase activity GO:0051096 11 5 1,000 5,094E-04 0,01442012 ! negative regulation of bone resorption GO:0045779 10 5 1,000 5,094E-04 0,01425244 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 1,000 5,094E-04 0,01408862 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 1,000 5,094E-04 0,01392852 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 1,000 5,094E-04 0,01377202 ! microvillus organization GO:0032528 7 5 1,000 5,094E-04 0,013619 GO:0030033|microvillus assembly, ! positive regulation of transporter activity GO:0032411 8 5 1,000 5,094E-04 0,01346934 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 5,094E-04 0,01332294 ! early endosome to late endosome transport GO:0045022 12 5 1,000 5,094E-04 0,01317968 ! neural tube patterning GO:0021532 7 5 1,000 5,094E-04 0,01303947 ! B cell homeostasis GO:0001782 13 5 1,000 5,094E-04 0,01290221 ! striatum development GO:0021756 9 5 1,000 5,094E-04 0,01276781 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 1,000 5,094E-04 0,01263619 ! stem cell division GO:0017145 11 5 1,000 5,094E-04 0,01250725 GO:0048103|somatic stem cell division, ! positive regulation of epithelial cell proliferation GO:0050679 64 22 2,000 5,135E-04 0,01247893 ! apoptotic nuclear changes GO:0030262 32 22 2,000 5,135E-04 0,01235414 ! positive regulation of intracellular transport GO:0032388 37 22 2,000 5,135E-04 0,01223182 ! carbohydrate biosynthetic process GO:0016051 141 93 4,000 5,762E-04 0,0135908 ! sex determination GO:0007530 47 23 2,000 5,874E-04 0,01372041 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 2,000 5,874E-04 0,01358848 ! interphase of mitotic cell cycle GO:0051329 209 95 4,000 6,349E-04 0,01454896 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 2,000 6,677E-04 0,01515602 ! negative regulation of phosphorylation GO:0042326 47 24 2,000 6,677E-04 0,01501437 ! alditol metabolic process GO:0019400 38 24 2,000 6,677E-04 0,01487535 ! protein tetramerization GO:0051262 52 24 2,000 6,677E-04 0,01473888 ! aging GO:0007568 103 55 3,000 6,705E-04 0,01466626 ! gastrulation GO:0007369 112 55 3,000 6,705E-04 0,01453413 ! interphase GO:0051325 213 98 4,000 7,313E-04 0,01571082 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 2,000 7,548E-04 0,01607035 ! vasculogenesis GO:0001570 46 25 2,000 7,548E-04 0,01592938 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 2,000 7,548E-04 0,01579087 ! sperm motility GO:0030317 31 25 2,000 7,548E-04 0,01565474 ! response to endoplasmic reticulum stress GO:0034976 43 25 2,000 7,548E-04 0,01552094 ! neural tube closure GO:0001843 49 25 2,000 7,548E-04 0,01538941 GO:0060606|tube closure, ! photoreceptor cell development GO:0042461 10 6 1,000 7,605E-04 0,01537672 GO:0046530|photoreceptor cell differentiation, ! toxin metabolic process GO:0009404 11 6 1,000 7,605E-04 0,01524858 ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 1,000 7,605E-04 0,01512256 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! neuron apoptosis GO:0051402 9 6 1,000 7,605E-04 0,0149986 ! purine base biosynthetic process GO:0009113 17 6 1,000 7,605E-04 0,01487666 ! subpallium development GO:0021544 10 6 1,000 7,605E-04 0,01475669 ! negative regulation of neuroblast proliferation GO:0007406 21 6 1,000 7,605E-04 0,01463864 ! determination of adult lifespan GO:0008340 15 6 1,000 7,605E-04 0,01452246 ! sensory cilium assembly GO:0035058 10 6 1,000 7,605E-04 0,01440811 ! regulation of intracellular transport GO:0032386 101 57 3,000 7,679E-04 0,01443484 ! maintenance of location GO:0051235 118 57 3,000 7,679E-04 0,01432294 ! cell cycle arrest GO:0007050 213 100 4,000 8,014E-04 0,01483264 ! tube lumen formation GO:0035148 50 26 2,000 8,487E-04 0,01558743 ! regulation of transcription factor import into nucleus GO:0042990 54 26 2,000 8,487E-04 0,01546934 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 2,000 8,487E-04 0,01535303 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of fibroblast proliferation GO:0048145 52 27 2,000 9,497E-04 0,0170526 ! neuron fate commitment GO:0048663 48 27 2,000 9,497E-04 0,01692628 ! protein amino acid acylation GO:0043543 55 27 2,000 9,497E-04 0,01680182 ! primary neural tube formation GO:0014020 51 27 2,000 9,497E-04 0,01667918 ! regulation of chromosome organization GO:0033044 42 27 2,000 9,497E-04 0,01655832 ! negative regulation of neuron differentiation GO:0045665 42 27 2,000 9,497E-04 0,01643919 ! dendrite development GO:0016358 59 28 2,000 1,058E-03 0,01818374 ! ER-nuclear signaling pathway GO:0006984 48 28 2,000 1,058E-03 0,01805478 ! cytokinesis during cell cycle GO:0033205 11 7 1,000 1,06E-03 0,0179549 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 1,000 1,06E-03 0,01782935 ! prostate gland development GO:0030850 13 7 1,000 1,06E-03 0,01770553 ! Golgi to plasma membrane transport GO:0006893 14 7 1,000 1,06E-03 0,01758342 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 1,06E-03 0,01746299 ! mRNA stabilization GO:0048255 18 7 1,000 1,06E-03 0,01734419 GO:0043489|RNA stabilization, ! induction of apoptosis by oxidative stress GO:0008631 8 7 1,000 1,06E-03 0,017227 ! maintenance of protein location in nucleus GO:0051457 19 7 1,000 1,06E-03 0,01711139 ! negative regulation of DNA recombination GO:0045910 15 7 1,000 1,06E-03 0,01699731 ! G1 DNA damage checkpoint GO:0031571 21 7 1,000 1,06E-03 0,01688474 ! B cell lineage commitment GO:0002326 21 7 1,000 1,06E-03 0,01677366 ! cell differentiation in hindbrain GO:0021533 10 7 1,000 1,06E-03 0,01666403 ! T cell lineage commitment GO:0002360 16 7 1,000 1,06E-03 0,01655582 ! response to tumor cell GO:0002347 13 7 1,000 1,06E-03 0,01644901 ! retina homeostasis GO:0001895 12 7 1,000 1,06E-03 0,01634357 ! cellular response to extracellular stimulus GO:0031668 48 29 2,000 1,174E-03 0,01799016 ! positive regulation of cell motion GO:0051272 146 64 3,000 1,188E-03 0,01808621 ! actin filament organization GO:0007015 148 66 3,000 1,332E-03 0,02015951 ! cell projection assembly GO:0030031 120 66 3,000 1,332E-03 0,02003351 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 1,406E-03 0,02101446 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 1,000 1,406E-03 0,02088474 GO:0016446|somatic hypermutation of immunoglobulin genes, ! signal peptide processing GO:0006465 12 8 1,000 1,406E-03 0,02075662 ! T-helper 1 type immune response GO:0042088 12 8 1,000 1,406E-03 0,02063005 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 1,406E-03 0,02050502 ! positive regulation of endothelial cell migration GO:0010595 19 8 1,000 1,406E-03 0,0203815 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 1,000 1,406E-03 0,02025945 ! regulation of vascular permeability GO:0043114 12 8 1,000 1,406E-03 0,02013886 ! melanosome transport GO:0032402 13 8 1,000 1,406E-03 0,0200197 ! multicellular organismal aging GO:0010259 18 8 1,000 1,406E-03 0,01990193 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 1,000 1,406E-03 0,01978555 ! negative regulation of protein kinase activity GO:0006469 130 67 3,000 1,409E-03 0,01970843 ! negative regulation of cell growth GO:0030308 132 67 3,000 1,409E-03 0,01959451 ! negative regulation of kinase activity GO:0033673 131 68 3,000 1,489E-03 0,020584 ! regulation of protein import into nucleus GO:0042306 63 32 2,000 1,568E-03 0,02156307 ! peripheral nervous system development GO:0007422 64 32 2,000 1,568E-03 0,02144055 ! negative regulation of cell size GO:0045792 134 69 3,000 1,571E-03 0,02136052 ! urogenital system development GO:0001655 137 69 3,000 1,571E-03 0,02124051 ! formation of primary germ layer GO:0001704 72 33 2,000 1,716E-03 0,02306695 ! cell fate specification GO:0001708 52 33 2,000 1,716E-03 0,0229388 ! negative regulation of protein transport GO:0051224 69 33 2,000 1,716E-03 0,02281206 ! reproductive structure development GO:0048608 113 71 3,000 1,747E-03 0,02308838 ! induction of positive chemotaxis GO:0050930 15 9 1,000 1,799E-03 0,02365771 ! regulation of activated T cell proliferation GO:0046006 16 9 1,000 1,799E-03 0,02352914 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 1,000 1,799E-03 0,02340195 ! microtubule bundle formation GO:0001578 21 9 1,000 1,799E-03 0,02327614 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 1,000 1,799E-03 0,02315166 ! receptor clustering GO:0043113 18 9 1,000 1,799E-03 0,02302852 ! motor axon guidance GO:0008045 16 9 1,000 1,799E-03 0,02290667 ! establishment of melanosome localization GO:0032401 14 9 1,000 1,799E-03 0,02278611 ! postreplication repair GO:0006301 22 9 1,000 1,799E-03 0,02266681 ! synaptic vesicle endocytosis GO:0048488 20 9 1,000 1,799E-03 0,02254876 ! regulation of cell division GO:0051302 15 9 1,000 1,799E-03 0,02243192 ! purine base metabolic process GO:0006144 21 9 1,000 1,799E-03 0,0223163 ! pigment granule transport GO:0051904 17 9 1,000 1,799E-03 0,02220185 ! phosphoinositide metabolic process GO:0030384 128 72 3,000 1,839E-03 0,02257378 ! negative regulation of transferase activity GO:0051348 140 72 3,000 1,839E-03 0,0224592 ! learning or memory GO:0007611 147 73 3,000 1,935E-03 0,0235094 ! negative regulation of DNA metabolic process GO:0051053 61 35 2,000 2,037E-03 0,02462814 ! regulation of microtubule-based process GO:0032886 78 35 2,000 2,037E-03 0,024505 ! neural tube formation GO:0001841 67 35 2,000 2,037E-03 0,02438308 ! cell-matrix adhesion GO:0007160 163 75 3,000 2,136E-03 0,02544712 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 2,000 2,21E-03 0,0261988 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 2,239E-03 0,0264022 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 1,000 2,239E-03 0,02627341 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 1,000 2,239E-03 0,02614586 ! lung alveolus development GO:0048286 26 10 1,000 2,239E-03 0,02601956 ! negative regulation of striated muscle development GO:0045843 19 10 1,000 2,239E-03 0,02589446 ! nucleobase biosynthetic process GO:0046112 24 10 1,000 2,239E-03 0,02577057 ! epithelial cell development GO:0002064 20 10 1,000 2,239E-03 0,02564785 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 1,000 2,239E-03 0,02552629 ! regulation of bone resorption GO:0045124 25 10 1,000 2,239E-03 0,02540589 ! brain morphogenesis GO:0048854 23 10 1,000 2,239E-03 0,02528661 ! melanosome localization GO:0032400 16 10 1,000 2,239E-03 0,02516845 ! positive regulation of leukocyte migration GO:0002687 25 10 1,000 2,239E-03 0,02505139 ! negative regulation of BMP signaling pathway GO:0030514 19 10 1,000 2,239E-03 0,02493541 ! establishment of pigment granule localization GO:0051905 18 10 1,000 2,239E-03 0,0248205 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 1,000 2,239E-03 0,02470664 ! localization within membrane GO:0051668 20 10 1,000 2,239E-03 0,02459383 ! regulation of protein stability GO:0031647 73 37 2,000 2,393E-03 0,02616874 ! glycogen metabolic process GO:0005977 61 37 2,000 2,393E-03 0,02605033 ! protein oligomerization GO:0051259 139 78 3,000 2,466E-03 0,02672228 ! nucleus organization GO:0006997 67 38 2,000 2,584E-03 0,02788188 ! embryonic epithelial tube formation GO:0001838 72 38 2,000 2,584E-03 0,02775741 ! glucan metabolic process GO:0044042 62 38 2,000 2,584E-03 0,02763404 GO:0006073|cellular glucan metabolic process, ! negative regulation of muscle development GO:0048635 20 11 1,000 2,723E-03 0,02899009 ! neuron fate specification GO:0048665 17 11 1,000 2,723E-03 0,02886238 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 1,000 2,723E-03 0,02873579 ! blood vessel remodeling GO:0001974 29 11 1,000 2,723E-03 0,02861031 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 1,000 2,723E-03 0,02848591 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 1,000 2,723E-03 0,0283626 ! regulation of intracellular pH GO:0051453 19 11 1,000 2,723E-03 0,02824035 ! pigment granule localization GO:0051875 20 11 1,000 2,723E-03 0,02811914 ! regulation of leukocyte migration GO:0002685 26 11 1,000 2,723E-03 0,02799897 ! positive regulation of neuron differentiation GO:0045666 19 11 1,000 2,723E-03 0,02787983 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 1,000 2,723E-03 0,0277617 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! response to hypoxia GO:0001666 171 81 3,000 2,828E-03 0,02871073 ! cell-substrate adhesion GO:0031589 171 81 3,000 2,828E-03 0,0285901 ! response to oxygen levels GO:0070482 176 83 3,000 3,089E-03 0,03109718 ! T cell differentiation GO:0030217 81 41 2,000 3,214E-03 0,03222247 ! regulation of T cell differentiation GO:0045580 70 41 2,000 3,214E-03 0,03208877 ! polyol metabolic process GO:0019751 66 41 2,000 3,214E-03 0,03195617 ! dorsal/ventral pattern formation GO:0009953 68 41 2,000 3,214E-03 0,03182466 ! negative regulation of growth GO:0045926 155 84 3,000 3,225E-03 0,03180514 ! cartilage condensation GO:0001502 20 12 1,000 3,252E-03 0,03193831 ! regulation of positive chemotaxis GO:0050926 19 12 1,000 3,252E-03 0,03180848 GO:0050927|positive regulation of positive chemotaxis, ! dopamine receptor signaling pathway GO:0007212 28 12 1,000 3,252E-03 0,0316797 ! regulation of cell projection assembly GO:0060491 30 12 1,000 3,252E-03 0,03155196 ! hippocampus development GO:0021766 26 12 1,000 3,252E-03 0,03142524 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 1,000 3,252E-03 0,03129954 ! protein homotetramerization GO:0051289 21 12 1,000 3,252E-03 0,03117484 ! immunoglobulin production during immune response GO:0002381 23 12 1,000 3,252E-03 0,03105113 ! T cell homeostasis GO:0043029 25 12 1,000 3,252E-03 0,0309284 ! regulation of RNA splicing GO:0043484 20 12 1,000 3,252E-03 0,03080664 ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 1,000 3,252E-03 0,03068583 ! mitochondrion organization GO:0007005 148 86 3,000 3,511E-03 0,03299325 ! alcohol catabolic process GO:0046164 130 86 3,000 3,511E-03 0,03286487 ! regulation of protein transport GO:0051223 154 87 3,000 3,659E-03 0,03412457 GO:0070201|regulation of establishment of protein localization, ! regulation of epithelial cell proliferation GO:0050678 111 43 2,000 3,682E-03 0,03420445 ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 1,000 3,825E-03 0,03539935 ! endocrine pancreas development GO:0031018 22 13 1,000 3,825E-03 0,03526372 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 1,000 3,825E-03 0,03512913 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cell-cell junction assembly GO:0007043 27 13 1,000 3,825E-03 0,03499556 ! response to X-ray GO:0010165 25 13 1,000 3,825E-03 0,034863 ! regulation of cellular pH GO:0030641 22 13 1,000 3,825E-03 0,03473144 ! regulation of monooxygenase activity GO:0032768 33 13 1,000 3,825E-03 0,03460087 ! regulation of mRNA stability GO:0043488 31 13 1,000 3,825E-03 0,03447128 ! male sex differentiation GO:0046661 76 44 2,000 3,931E-03 0,03528801 ! branching morphogenesis of a tube GO:0048754 97 45 2,000 4,189E-03 0,03747007 ! hair follicle morphogenesis GO:0031069 26 14 1,000 4,442E-03 0,03958156 ! actin cytoskeleton reorganization GO:0031532 33 14 1,000 4,442E-03 0,0394355 ! negative regulation of protein import into nucleus GO:0042308 30 14 1,000 4,442E-03 0,03929052 ! response to gamma radiation GO:0010332 28 14 1,000 4,442E-03 0,0391466 ! regulation of RNA stability GO:0043487 32 14 1,000 4,442E-03 0,03900372 ! positive regulation of protein transport GO:0051222 72 46 2,000 4,458E-03 0,0390037 ! positive regulation of MAP kinase activity GO:0043406 160 93 3,000 4,642E-03 0,04046809 ! regulation of T cell activation GO:0050863 158 94 3,000 4,822E-03 0,04188052 ! cellular component disassembly GO:0022411 86 48 2,000 5,026E-03 0,04350056 ! morphogenesis of embryonic epithelium GO:0016331 91 48 2,000 5,026E-03 0,04334464 ! activation of caspase activity GO:0006919 84 48 2,000 5,026E-03 0,04318984 ! regulation of lymphocyte differentiation GO:0045619 81 48 2,000 5,026E-03 0,04303614 ! negative regulation of bone remodeling GO:0046851 33 15 1,000 5,101E-03 0,0435209 ! regulation of transmembrane transporter activity GO:0022898 27 15 1,000 5,101E-03 0,04336711 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 1,000 5,101E-03 0,04321441 ! G1/S transition checkpoint GO:0031575 40 15 1,000 5,101E-03 0,04306278 ! muscle maintenance GO:0046716 26 15 1,000 5,101E-03 0,04291221 ! dopamine metabolic process GO:0042417 35 15 1,000 5,101E-03 0,04276269 ! lymphocyte homeostasis GO:0002260 30 15 1,000 5,101E-03 0,04261421 ! regulation of DNA metabolic process GO:0051052 178 97 3,000 5,388E-03 0,04485452 ! regulation of protein localization GO:0032880 176 97 3,000 5,388E-03 0,04469985 ! histone modification GO:0016570 91 50 2,000 5,636E-03 0,04660018 ! G1 phase of mitotic cell cycle GO:0000080 35 16 1,000 5,802E-03 0,0478079 ! embryonic forelimb morphogenesis GO:0035115 28 16 1,000 5,802E-03 0,04764473 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 1,000 5,802E-03 0,04748267 ! regulation of neurotransmitter secretion GO:0046928 33 16 1,000 5,802E-03 0,04732171 ! induction of apoptosis via death domain receptors GO:0008625 20 16 1,000 5,802E-03 0,04716184 ! negative regulation of microtubule depolymerization GO:0007026 46 16 1,000 5,802E-03 0,04700305 GO:0031114|regulation of microtubule depolymerization, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 1,000 5,802E-03 0,04684532 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! positive regulation of protein import into nucleus GO:0042307 30 16 1,000 5,802E-03 0,04668865 ! negative regulation of tissue remodeling GO:0034104 36 16 1,000 5,802E-03 0,04653302 ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 5,802E-03 0,04637842 ! epithelial tube morphogenesis GO:0060562 98 51 2,000 5,957E-03 0,04745905 ! covalent chromatin modification GO:0016569 101 52 2,000 6,289E-03 0,04993533 ! morphogenesis of a branching structure GO:0001763 111 52 2,000 6,289E-03 0,04977107 ! signal complex assembly GO:0007172 41 17 1,000 6,545E-03 0,05162798 ! limbic system development GO:0021761 36 17 1,000 6,545E-03 0,05145926 ! heart looping GO:0001947 30 17 1,000 6,545E-03 0,05129164 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 1,000 6,545E-03 0,05112511 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 1,000 6,545E-03 0,05095966 ! negative regulation of protein catabolic process GO:0042177 40 17 1,000 6,545E-03 0,05079527 ! nucleobase metabolic process GO:0009112 37 17 1,000 6,545E-03 0,05063194 ! negative regulation of homeostatic process GO:0032845 33 17 1,000 6,545E-03 0,05046966 ! microspike assembly GO:0030035 36 17 1,000 6,545E-03 0,05030841 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 1,000 6,545E-03 0,0501482 ! glutamine family amino acid metabolic process GO:0009064 78 54 2,000 6,984E-03 0,05334657 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 7,328E-03 0,05579515 ! epidermis morphogenesis GO:0048730 40 18 1,000 7,328E-03 0,05561914 ! peptidyl-serine phosphorylation GO:0018105 38 18 1,000 7,328E-03 0,05544423 ! regulation of BMP signaling pathway GO:0030510 32 18 1,000 7,328E-03 0,05527043 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 1,000 7,328E-03 0,05509771 ! positive regulation of caspase activity GO:0043280 95 55 2,000 7,349E-03 0,05507965 GO:0010952|positive regulation of peptidase activity, ! cellular polysaccharide metabolic process GO:0044264 86 55 2,000 7,349E-03 0,05490859 ! negative regulation of cell motion GO:0051271 134 55 2,000 7,349E-03 0,0547386 ! regulation of actin filament length GO:0030832 105 56 2,000 7,724E-03 0,05735667 ! regulation of DNA replication GO:0006275 101 56 2,000 7,724E-03 0,05718019 ! positive regulation of cell migration GO:0030335 126 57 2,000 8,11E-03 0,05985685 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 1,000 8,152E-03 0,0599774 ! lipid phosphorylation GO:0046834 35 19 1,000 8,152E-03 0,05979454 ! forelimb morphogenesis GO:0035136 32 19 1,000 8,152E-03 0,0596128 ! cerebral cortex development GO:0021987 36 19 1,000 8,152E-03 0,05943215 ! neuromuscular junction development GO:0007528 34 19 1,000 8,152E-03 0,0592526 ! regulation of endothelial cell migration GO:0010594 44 19 1,000 8,152E-03 0,05907413 ! cellular pigmentation GO:0033059 36 19 1,000 8,152E-03 0,05889673 ! G1 phase GO:0051318 40 19 1,000 8,152E-03 0,05872039 ! cell-cell junction organization GO:0045216 35 19 1,000 8,152E-03 0,05854511 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 1,000 8,152E-03 0,05837086 ! cilium assembly GO:0042384 37 19 1,000 8,152E-03 0,05819766 ! regulation of cellular component size GO:0032535 109 59 2,000 8,917E-03 0,06347306 ! DNA catabolic process GO:0006308 86 59 2,000 8,917E-03 0,06328582 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 1,000 9,015E-03 0,06379144 ! pancreas development GO:0031016 35 20 1,000 9,015E-03 0,06360437 ! photoreceptor cell maintenance GO:0045494 34 20 1,000 9,015E-03 0,06341839 ! cellular response to starvation GO:0009267 33 20 1,000 9,015E-03 0,0632335 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 1,000 9,015E-03 0,06304968 ! peptidyl-serine modification GO:0018209 43 20 1,000 9,015E-03 0,06286693 ! leukotriene biosynthetic process GO:0019370 37 20 1,000 9,015E-03 0,06268523 GO:0043450|alkene biosynthetic process, ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 1,000 9,015E-03 0,06250458 ! DNA damage response, signal transduction GO:0042770 128 60 2,000 9,337E-03 0,0645546 ! protein amino acid autophosphorylation GO:0046777 141 60 2,000 9,337E-03 0,06436963 ! mesoderm development GO:0007498 119 61 2,000 9,769E-03 0,06715293 ! hindlimb morphogenesis GO:0035137 43 21 1,000 9,917E-03 0,06797505 ! regulation of neurotransmitter transport GO:0051588 42 21 1,000 9,917E-03 0,06778194 ! axis specification GO:0009798 38 21 1,000 9,917E-03 0,06758992 ! cell aging GO:0007569 44 21 1,000 9,917E-03 0,06739899 ! positive regulation of locomotion GO:0040017 39 21 1,000 9,917E-03 0,06720914 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! negative regulation of intracellular transport GO:0032387 41 21 1,000 9,917E-03 0,06702035 ! gonad development GO:0008406 98 62 2,000 0,01021181 0,06882244 ! regulation of chemotaxis GO:0050920 40 22 1,000 0,01085687 0,07296544 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 1,000 0,01085687 0,07276219 ! positive regulation of B cell activation GO:0050871 38 22 1,000 0,01085687 0,07256007 ! activation of JUN kinase activity GO:0007257 42 22 1,000 0,01085687 0,07235907 ! somatic diversification of immunoglobulins GO:0016445 50 22 1,000 0,01085687 0,07215919 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 1,000 0,01085687 0,0719604 ! protein stabilization GO:0050821 39 22 1,000 0,01085687 0,07176271 ! germ cell development GO:0007281 118 65 2,000 0,01161035 0,07653292 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 0,01183492 0,07780003 ! gluconeogenesis GO:0006094 33 23 1,000 0,01183492 0,07758804 ! regulation of cell-matrix adhesion GO:0001952 78 23 1,000 0,01183492 0,0773772 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 48 23 1,000 0,01183492 0,0771675 ! leukotriene metabolic process GO:0006691 42 23 1,000 0,01183492 0,07695894 ! synaptic vesicle transport GO:0048489 46 23 1,000 0,01183492 0,07675151 ! negative regulation of catabolic process GO:0009895 50 23 1,000 0,01183492 0,07654519 ! developmental maturation GO:0021700 116 66 2,000 0,01209979 0,07804851 ! adaptive immune response GO:0002250 119 67 2,000 0,01260092 0,0810637 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! protein import into nucleus, translocation GO:0000060 46 24 1,000 0,01285012 0,08244635 ! positive regulation of fibroblast proliferation GO:0048146 43 24 1,000 0,01285012 0,08222707 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 1,000 0,01285012 0,08200896 GO:0016444|somatic cell DNA recombination, ! regulation of transmembrane transport GO:0034762 38 24 1,000 0,01285012 0,08179201 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 1,000 0,01285012 0,0815762 ! regulation of behavior GO:0050795 43 24 1,000 0,01285012 0,08136152 ! pallium development GO:0021543 49 24 1,000 0,01285012 0,08114798 ! regulation of oxidoreductase activity GO:0051341 46 24 1,000 0,01285012 0,08093555 ! leukocyte homeostasis GO:0001776 44 24 1,000 0,01285012 0,08072423 ! cellular alkene metabolic process GO:0043449 43 24 1,000 0,01285012 0,08051401 ! cell cycle checkpoint GO:0000075 137 69 2,000 0,01363845 0,08523148 ! myelination GO:0042552 45 25 1,000 0,01390189 0,08665269 ! negative regulation of DNA replication GO:0008156 42 25 1,000 0,01390189 0,08642878 ! receptor metabolic process GO:0043112 46 25 1,000 0,01390189 0,08620603 ! response to starvation GO:0042594 42 25 1,000 0,01390189 0,08598442 ! negative regulation of cell development GO:0010721 73 25 1,000 0,01390189 0,08576394 GO:0050768|negative regulation of neurogenesis, ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 1,000 0,01390189 0,0855446 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 1,000 0,01390189 0,08532637 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 1,000 0,01390189 0,08510926 ! immunoglobulin production GO:0002377 55 25 1,000 0,01390189 0,08489324 GO:0002440|production of molecular mediator of immune response, ! cellular response to nutrient levels GO:0031669 41 25 1,000 0,01390189 0,08467833 ! B cell activation GO:0042113 160 71 2,000 0,01472323 0,0894548 ! pyruvate metabolic process GO:0006090 38 26 1,000 0,01498965 0,09084409 ! molting cycle process GO:0022404 50 26 1,000 0,01498965 0,09061584 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! microtubule organizing center organization GO:0031023 39 26 1,000 0,01498965 0,09038873 GO:0051297|centrosome organization, ! insulin receptor signaling pathway GO:0008286 64 26 1,000 0,01498965 0,09016276 ! regulation of endothelial cell proliferation GO:0001936 57 26 1,000 0,01498965 0,08993792 ! somatic diversification of immune receptors GO:0002200 56 26 1,000 0,01498965 0,08971419 ! positive regulation of JUN kinase activity GO:0043507 51 26 1,000 0,01498965 0,08949157 ! regulation of caspase activity GO:0043281 122 72 2,000 0,01528342 0,09101958 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 1,000 0,01611285 0,09572224 ! positive regulation of cell projection organization GO:0031346 58 27 1,000 0,01611285 0,09548647 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 1,000 0,01611285 0,09525186 ! fat cell differentiation GO:0045444 50 27 1,000 0,01611285 0,0950184 ! mitochondrial membrane organization GO:0007006 57 27 1,000 0,01611285 0,09478608 ! male gonad development GO:0008584 44 27 1,000 0,01611285 0,0945549 ! response to toxin GO:0009636 47 27 1,000 0,01611285 0,09432484 ! base-excision repair GO:0006284 41 27 1,000 0,01611285 0,09409589 ! regulation of actin cytoskeleton organization GO:0032956 149 74 2,000 0,01643952 0,09577117 ! regulation of endopeptidase activity GO:0052548 125 74 2,000 0,01643952 0,09553984 ! eye development GO:0001654 143 74 2,000 0,01643952 0,09530962 ! lymphocyte differentiation GO:0030098 167 75 2,000 0,01703548 0,09852734 ! regulation of JUN kinase activity GO:0043506 58 28 1,000 0,01727091 0,0996494 ! development of primary sexual characteristics GO:0045137 124 76 2,000 0,01764341 0,10155514 ! regulation of actin filament-based process GO:0032970 152 77 2,000 0,01826332 0,10487244 ! icosanoid biosynthetic process GO:0046456 54 29 1,000 0,01846328 0,10576819 ! regulation of pH GO:0006885 43 29 1,000 0,01846328 0,10551696 ! catechol metabolic process GO:0009712 54 29 1,000 0,01846328 0,10526692 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 1,000 0,01846328 0,10501806 ! tissue homeostasis GO:0001894 48 29 1,000 0,01846328 0,10477038 GO:0048871|multicellular organismal homeostasis, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 2,000 0,01889523 0,10696922 ! regulation of peptidase activity GO:0052547 134 79 2,000 0,01953914 0,11035489 ! regulation of synaptic transmission GO:0050804 134 79 2,000 0,01953914 0,11009644 ! phenol metabolic process GO:0018958 55 30 1,000 0,0196894 0,11068389 ! ensheathment of neurons GO:0007272 57 30 1,000 0,0196894 0,11042589 GO:0008366|axon ensheathment, ! eye morphogenesis GO:0048592 60 30 1,000 0,0196894 0,11016909 ! T cell activation GO:0042110 168 81 2,000 0,02086304 0,11646513 ! regulation of neuron differentiation GO:0045664 167 81 2,000 0,02086304 0,11619554 ! mesoderm formation GO:0001707 69 31 1,000 0,02094875 0,11640345 ! pigment biosynthetic process GO:0046148 66 32 1,000 0,02224077 0,12329793 ! metanephros development GO:0001656 74 32 1,000 0,02224077 0,12301449 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 1,000 0,02224077 0,12273235 ! response to ionizing radiation GO:0010212 65 32 1,000 0,02224077 0,12245149 ! hindbrain development GO:0030902 61 32 1,000 0,02224077 0,12217192 ! negative regulation of transport GO:0051051 153 84 2,000 0,02293911 0,12572097 ! regulation of transmission of nerve impulse GO:0051969 141 84 2,000 0,02293911 0,12543524 ! DNA damage checkpoint GO:0000077 71 33 1,000 0,02356495 0,12856521 ! establishment of vesicle localization GO:0051650 61 33 1,000 0,02356495 0,12827434 ! positive regulation of endocytosis GO:0045807 50 34 1,000 0,02492074 0,1353483 ! regulation of striated muscle tissue development GO:0016202 69 34 1,000 0,02492074 0,13504346 ! mesoderm morphogenesis GO:0048332 76 34 1,000 0,02492074 0,13473999 ! mismatch repair GO:0006298 46 34 1,000 0,02492074 0,13443788 ! spermatid development GO:0007286 63 34 1,000 0,02492074 0,13413713 ! protein localization in nucleus GO:0034504 176 87 2,000 0,02512347 0,13492651 ! gland development GO:0048732 206 88 2,000 0,02587564 0,13865653 ! regulation of neurological system process GO:0031644 148 88 2,000 0,02587564 0,1383484 ! regulation of muscle development GO:0048634 70 35 1,000 0,02630763 0,14034626 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 1,000 0,02630763 0,14003576 ! regulation of synaptic plasticity GO:0048167 64 35 1,000 0,02630763 0,13972663 ! negative regulation of cell adhesion GO:0007162 81 35 1,000 0,02630763 0,13941886 ! telencephalon development GO:0021537 68 35 1,000 0,02630763 0,13911244 ! negative regulation of hydrolase activity GO:0051346 62 35 1,000 0,02630763 0,13880737 ! calcium-mediated signaling GO:0019722 62 35 1,000 0,02630763 0,13850364 ! vesicle localization GO:0051648 64 35 1,000 0,02630763 0,13820123 ! regulation of cell adhesion GO:0030155 212 89 2,000 0,02663981 0,13964133 ! ossification GO:0001503 188 90 2,000 0,02741597 0,14339745 ! sex differentiation GO:0007548 145 90 2,000 0,02741597 0,14308639 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 1,000 0,02772511 0,14438663 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! DNA integrity checkpoint GO:0031570 75 36 1,000 0,02772511 0,14407478 ! androgen receptor signaling pathway GO:0030521 74 36 1,000 0,02772511 0,14376427 ! bone development GO:0060348 189 91 2,000 0,02820412 0,14593357 ! meiosis I GO:0007127 65 37 1,000 0,02917267 0,15062114 ! tissue remodeling GO:0048771 76 37 1,000 0,02917267 0,15029861 ! monovalent inorganic cation homeostasis GO:0055067 58 37 1,000 0,02917267 0,14997746 ! pigment metabolic process GO:0042440 80 37 1,000 0,02917267 0,14965767 ! spermatid differentiation GO:0048515 66 37 1,000 0,02917267 0,14933925 ! cellular response to insulin stimulus GO:0032869 82 37 1,000 0,02917267 0,14902219 ! transcription initiation GO:0006352 153 94 2,000 0,0306403 0,15618764 ! mitotic cell cycle checkpoint GO:0007093 76 38 1,000 0,03064981 0,15590579 ! carbohydrate homeostasis GO:0033500 53 38 1,000 0,03064981 0,15557687 GO:0042593|glucose homeostasis, ! positive regulation of leukocyte proliferation GO:0070665 62 38 1,000 0,03064981 0,15524934 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! forebrain development GO:0030900 188 95 2,000 0,03147621 0,15910036 ! mammary gland development GO:0030879 86 39 1,000 0,03215602 0,16219579 ! learning GO:0007612 77 39 1,000 0,03215602 0,16185646 ! development of primary male sexual characteristics GO:0046546 66 39 1,000 0,03215602 0,16151856 ! segmentation GO:0035282 67 39 1,000 0,03215602 0,16118206 ! regulation of action potential in neuron GO:0019228 73 39 1,000 0,03215602 0,16084696 ! leukocyte differentiation GO:0002521 202 96 2,000 0,03232402 0,16135183 ! cytokinesis GO:0000910 72 40 1,000 0,03369082 0,16782634 ! skeletal muscle tissue development GO:0007519 186 99 2,000 0,03493851 0,17368195 GO:0060538|skeletal muscle organ development, ! keratinocyte differentiation GO:0030216 62 41 1,000 0,03525373 0,17488756 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,03551306 0,17581158 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,03551306 0,17545057 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,03551306 0,17509104 ! neuron fate determination GO:0048664 7 5 0,000 0,03551306 0,17473298 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,03551306 0,17437638 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,03551306 0,17402124 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,03551306 0,17366754 ! polyol transport GO:0015791 12 5 0,000 0,03551306 0,17331527 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,03551306 0,17296443 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,03551306 0,17261501 ! response to superoxide GO:0000303 10 5 0,000 0,03551306 0,17226699 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,03551306 0,17192038 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,03551306 0,17157516 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,03551306 0,17123132 ! female meiosis GO:0007143 7 5 0,000 0,03551306 0,17088886 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,03551306 0,17054776 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,03551306 0,17020802 ! cobalt ion transport GO:0006824 11 5 0,000 0,03551306 0,16986964 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,03551306 0,1695326 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,03551306 0,16919689 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,03551306 0,16886251 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,03551306 0,16852944 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,03551306 0,16819769 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,03551306 0,16786725 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,03551306 0,16753809 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,03551306 0,16721023 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,03551306 0,16688365 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,03551306 0,16655834 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,03551306 0,1662343 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,03551306 0,16591151 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,03551306 0,16558998 ! negative chemotaxis GO:0050919 14 5 0,000 0,03551306 0,16526969 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,03551306 0,16495063 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,03551306 0,16463281 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,03551306 0,16431621 ! behavioral response to pain GO:0048266 9 5 0,000 0,03551306 0,16400082 ! clathrin coat assembly GO:0048268 14 5 0,000 0,03551306 0,16368664 ! Notch receptor processing GO:0007220 8 5 0,000 0,03551306 0,16337367 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,03551306 0,16306189 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,03551306 0,16275129 ! micturition GO:0060073 9 5 0,000 0,03551306 0,16244188 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,03551306 0,16213364 ! copulation GO:0007620 9 5 0,000 0,03551306 0,16182657 ! glial cell fate commitment GO:0021781 13 5 0,000 0,03551306 0,16152066 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,03551306 0,1612159 ! spermidine metabolic process GO:0008216 7 5 0,000 0,03551306 0,16091229 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,03551306 0,16060983 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,03551306 0,1603085 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,03551306 0,16000829 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,03551306 0,15970921 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,03551306 0,15941125 ! grooming behavior GO:0007625 6 5 0,000 0,03551306 0,15911439 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,03551306 0,15881864 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,03551306 0,15852399 ! response to protozoan GO:0001562 10 5 0,000 0,03551306 0,15823042 ! positive regulation of glycolysis GO:0045821 14 5 0,000 0,03551306 0,15793794 ! lymph vessel development GO:0001945 10 5 0,000 0,03551306 0,15764655 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,03551306 0,15735622 ! endochondral ossification GO:0001958 16 5 0,000 0,03551306 0,15706696 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,03551306 0,15677877 ! parathyroid gland development GO:0060017 13 5 0,000 0,03551306 0,15649163 ! anagen GO:0042640 6 5 0,000 0,03551306 0,15620554 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,03551306 0,15592049 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,03551306 0,15563648 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,03551306 0,15535351 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,03551306 0,15507156 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,03551306 0,15479063 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,03551306 0,15451072 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,03551306 0,15423182 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,03551306 0,15395392 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,03551306 0,15367703 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,03551306 0,15340113 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,03551306 0,15312622 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,03551306 0,15285229 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,03551306 0,15257934 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,03551306 0,15230736 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,03551306 0,15203635 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 0,03551306 0,1517663 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,03551306 0,15149721 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,03551306 0,15122908 ! histidine catabolic process GO:0006548 6 5 0,000 0,03551306 0,15096189 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,03551306 0,15069564 ! valine metabolic process GO:0006573 10 5 0,000 0,03551306 0,15043033 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,03551306 0,15016595 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,03551306 0,14990251 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,03551306 0,14963998 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,03551306 0,14937837 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,03551306 0,14911768 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,03551306 0,14885789 ! polyol biosynthetic process GO:0046173 5 5 0,000 0,03551306 0,14859901 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,03551306 0,14834102 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,03551306 0,14808393 ! muscle cell migration GO:0014812 8 5 0,000 0,03551306 0,14782773 ! mitochondrial fission GO:0000266 8 5 0,000 0,03551306 0,14757241 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,03551306 0,14731798 ! mRNA transcription GO:0009299 9 5 0,000 0,03551306 0,14706442 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,03551306 0,14681173 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,03551306 0,14655991 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,03551306 0,14630895 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,03551306 0,14605885 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,03551306 0,1458096 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,03551306 0,14556121 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,03551306 0,14531365 ! response to food GO:0032094 6 5 0,000 0,03551306 0,14506694 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,03551306 0,14482106 ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,03551306 0,14457602 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,03551306 0,1443318 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,03551306 0,14408841 ! forebrain neuron development GO:0021884 13 5 0,000 0,03551306 0,14384584 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,03551306 0,14360408 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,03551306 0,14336313 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,03551306 0,143123 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,03551306 0,14288366 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,03551306 0,14264512 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,03551306 0,14240738 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,03551306 0,14217043 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,03551306 0,14193427 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,03551306 0,14169889 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,03551306 0,14146429 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,03551306 0,14123046 ! basic amino acid transport GO:0015802 11 5 0,000 0,03551306 0,14099741 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,03551306 0,14076512 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,03551306 0,1405336 ! depyrimidination GO:0045008 10 5 0,000 0,03551306 0,14030284 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,03551306 0,14007283 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,03551306 0,13984358 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,03551306 0,13961508 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,03551306 0,13938732 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 0,03551306 0,13916031 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,03551306 0,13893403 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,03551306 0,13870849 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,03551306 0,13848368 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,03551306 0,13825959 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,03551306 0,13803623 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,03551306 0,13781359 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,03551306 0,13759167 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,03551306 0,13737046 ! response to arsenic GO:0046685 10 5 0,000 0,03551306 0,13714996 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,03551306 0,13693017 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,03551306 0,13671109 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,03551306 0,1364927 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,03551306 0,13627501 ! response to cadmium ion GO:0046686 7 5 0,000 0,03551306 0,13605801 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,03551306 0,1358417 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,03551306 0,13562608 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,03551306 0,13541114 ! decidualization GO:0046697 11 5 0,000 0,03551306 0,13519688 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,03551306 0,1349833 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,03551306 0,13477039 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,03551306 0,13455815 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,03551306 0,13434659 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,03551306 0,13413568 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,03551306 0,13392544 ! embryonic cleavage GO:0040016 6 5 0,000 0,03551306 0,13371585 ! peroxisome fission GO:0016559 5 5 0,000 0,03551306 0,13350692 ! histone demethylation GO:0016577 10 5 0,000 0,03551306 0,13329864 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,03551306 0,13309101 ! mitotic recombination GO:0006312 9 5 0,000 0,03551306 0,13288403 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,03551306 0,13267768 ! metaphase plate congression GO:0051310 7 5 0,000 0,03551306 0,13247198 ! regulation of sterol transport GO:0032371 7 5 0,000 0,03551306 0,13226692 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,03551306 0,13206249 ! enteric nervous system development GO:0048484 8 5 0,000 0,03551306 0,13185869 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,03551306 0,13165551 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,03551306 0,13145297 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,03551306 0,13125104 ! muscle cell proliferation GO:0033002 11 5 0,000 0,03551306 0,13104974 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,03551306 0,13084905 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,03551306 0,13064897 ! plasminogen activation GO:0031639 5 5 0,000 0,03551306 0,13044951 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,03551306 0,13025065 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,03551306 0,1300524 ! metaphase GO:0051323 8 5 0,000 0,03551306 0,12985475 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,03551306 0,12965771 ! cellular response to nutrient GO:0031670 8 5 0,000 0,03551306 0,12946125 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,03551306 0,1292654 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,03551306 0,12907013 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,03551306 0,12887546 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,03551306 0,12868137 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,03551306 0,12848786 ! response to redox state GO:0051775 5 5 0,000 0,03551306 0,12829494 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,03551306 0,12810259 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,03551306 0,12791082 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,03551306 0,12771962 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,03551306 0,127529 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,03551306 0,12733894 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,03551306 0,12714945 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,03551306 0,12696052 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,03551306 0,12677215 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,03551306 0,12658434 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,03551306 0,12639708 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,03551306 0,12621038 ! glial cell migration GO:0008347 11 5 0,000 0,03551306 0,12602423 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,03551306 0,12583863 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,03551306 0,12565357 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,03551306 0,12546906 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,03551306 0,12528509 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,03551306 0,12510165 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,03551306 0,12491875 ! neuroprotection GO:0043526 6 5 0,000 0,03551306 0,12473639 ! neural plate development GO:0001840 8 5 0,000 0,03551306 0,12455456 ! regulation of sensory perception GO:0051931 7 5 0,000 0,03551306 0,12437326 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,03551306 0,12419248 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,03551306 0,12401223 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,03551306 0,1238325 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,03551306 0,1236533 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,03551306 0,12347461 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,03551306 0,12329643 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,03551306 0,12311877 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,03551306 0,12294162 ! spindle assembly GO:0051225 6 5 0,000 0,03551306 0,12276498 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,03551306 0,12258885 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,03551306 0,12241322 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,03551306 0,12223809 ! drug metabolic process GO:0017144 6 5 0,000 0,03551306 0,12206347 ! phospholipid scrambling GO:0017121 8 5 0,000 0,03551306 0,12188934 ! organ regeneration GO:0031100 7 5 0,000 0,03551306 0,12171571 ! carnitine metabolic process GO:0009437 7 5 0,000 0,03551306 0,12154257 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,03551306 0,12136993 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,03551306 0,12119777 ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 0,03684425 0,1255627 GO:0090047|positive regulation of transcription regulator activity, ! negative regulation of protein complex disassembly GO:0043242 101 42 1,000 0,03684425 0,12538511 ! neuron migration GO:0001764 79 42 1,000 0,03684425 0,12520801 ! receptor-mediated endocytosis GO:0006898 88 43 1,000 0,03846192 0,13052099 ! positive regulation of response to external stimulus GO:0032103 77 43 1,000 0,03846192 0,13033716 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 1,000 0,04010627 0,13571825 ! double-strand break repair GO:0006302 81 44 1,000 0,04010627 0,13552764 ! B cell differentiation GO:0030183 107 44 1,000 0,04010627 0,13533756 ! glycolysis GO:0006096 65 45 1,000 0,04177682 0,14077736 ! icosanoid metabolic process GO:0006690 80 45 1,000 0,04177682 0,14058047 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,04246357 0,14269183 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,04246357 0,14249281 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,04246357 0,14229436 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,04246357 0,14209645 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,04246357 0,14189909 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,04246357 0,14170229 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,04246357 0,14150602 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,04246357 0,1413103 ! sleep GO:0030431 13 6 0,000 0,04246357 0,14111512 ! response to oxygen radical GO:0000305 11 6 0,000 0,04246357 0,14092048 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,04246357 0,14072637 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,04246357 0,1405328 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,04246357 0,14033976 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,04246357 0,14014725 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,04246357 0,13995527 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,04246357 0,13976381 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,04246357 0,13957288 ! forebrain regionalization GO:0021871 8 6 0,000 0,04246357 0,13938247 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,04246357 0,13919257 ! male meiosis GO:0007140 7 6 0,000 0,04246357 0,13900319 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,04246357 0,13881433 ! response to zinc ion GO:0010043 9 6 0,000 0,04246357 0,13862598 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,04246357 0,13843814 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,04246357 0,13825081 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,04246357 0,13806398 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,04246357 0,13787766 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,04246357 0,13769184 ! malate metabolic process GO:0006108 11 6 0,000 0,04246357 0,13750652 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,04246357 0,1373217 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,04246357 0,13713738 ! protein refolding GO:0042026 15 6 0,000 0,04246357 0,13695355 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,04246357 0,13677021 ! opsonization GO:0008228 8 6 0,000 0,04246357 0,13658736 ! mating behavior GO:0007617 7 6 0,000 0,04246357 0,136405 ! neuron remodeling GO:0016322 15 6 0,000 0,04246357 0,13622313 ! erythrocyte maturation GO:0043249 7 6 0,000 0,04246357 0,13604174 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,04246357 0,13586083 ! equilibrioception GO:0050957 14 6 0,000 0,04246357 0,13568041 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,04246357 0,13550046 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,04246357 0,13532099 ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,04246357 0,13514199 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,04246357 0,13496347 ! response to interferon-gamma GO:0034341 15 6 0,000 0,04246357 0,13478542 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,04246357 0,13460784 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,04246357 0,13443072 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,04246357 0,13425407 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,04246357 0,13407788 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,04246357 0,13390216 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,04246357 0,1337269 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,04246357 0,13355209 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,04246357 0,13337774 ! thymic T cell selection GO:0045061 12 6 0,000 0,04246357 0,13320384 ! protein lipoylation GO:0009249 10 6 0,000 0,04246357 0,1330304 ! cysteine metabolic process GO:0006534 10 6 0,000 0,04246357 0,13285741 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,04246357 0,13268487 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,04246357 0,13251277 ! glutamate catabolic process GO:0006538 10 6 0,000 0,04246357 0,13234112 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,04246357 0,13216992 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! adenohypophysis development GO:0021984 10 6 0,000 0,04246357 0,13199916 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,04246357 0,13182884 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,04246357 0,13165895 ! hyperosmotic response GO:0006972 9 6 0,000 0,04246357 0,13148951 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,04246357 0,1313205 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,04246357 0,13115192 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,04246357 0,13098378 ! urea metabolic process GO:0019627 7 6 0,000 0,04246357 0,13081607 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,04246357 0,13064878 ! neutrophil activation GO:0042119 8 6 0,000 0,04246357 0,13048193 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,04246357 0,13031549 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,04246357 0,13014949 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,04246357 0,1299839 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,04246357 0,12981874 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,04246357 0,12965399 ! nucleoside salvage GO:0043174 9 6 0,000 0,04246357 0,12948967 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,04246357 0,12932576 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,04246357 0,12916226 ! T cell mediated immunity GO:0002456 16 6 0,000 0,04246357 0,12899918 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,04246357 0,1288365 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 0,04246357 0,12867424 ! carnitine transport GO:0015879 10 6 0,000 0,04246357 0,12851239 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,04246357 0,12835094 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,04246357 0,1281899 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,04246357 0,12802926 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,04246357 0,12786902 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,04246357 0,12770918 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,04246357 0,12754975 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,04246357 0,12739071 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,04246357 0,12723206 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,04246357 0,12707382 ! establishment of spindle localization GO:0051293 12 6 0,000 0,04246357 0,12691596 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,04246357 0,1267585 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,04246357 0,12660142 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,04246357 0,12644474 ! neural nucleus development GO:0048857 14 6 0,000 0,04246357 0,12628844 ! response to UV-C GO:0010225 11 6 0,000 0,04246357 0,12613253 ! astrocyte development GO:0014002 15 6 0,000 0,04246357 0,125977 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,04246357 0,12582186 ! interaction with symbiont GO:0051702 13 6 0,000 0,04246357 0,12566709 ! regulation of dendrite development GO:0050773 16 6 0,000 0,04246357 0,12551271 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,04246357 0,12535871 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,04246357 0,12520508 ! response to copper ion GO:0046688 10 6 0,000 0,04246357 0,12505183 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,04246357 0,12489896 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,04246357 0,12474646 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,04246357 0,12459433 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,04246357 0,12444257 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,04246357 0,12429118 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,04246357 0,12414016 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,04246357 0,1239895 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,04246357 0,12383921 ! hair follicle maturation GO:0048820 7 6 0,000 0,04246357 0,12368928 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,04246357 0,12353972 ! Schwann cell development GO:0014044 15 6 0,000 0,04246357 0,12339052 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,04246357 0,12324167 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,04246357 0,12309319 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,04246357 0,12294506 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,04246357 0,12279729 ! histone ubiquitination GO:0016574 8 6 0,000 0,04246357 0,12264988 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,04246357 0,12250282 ! maintenance of organ identity GO:0048496 9 6 0,000 0,04246357 0,12235611 ! G2 phase GO:0051319 16 6 0,000 0,04246357 0,12220975 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,04246357 0,12206374 ! establishment of planar polarity GO:0001736 7 6 0,000 0,04246357 0,12191808 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,04246357 0,12177276 ! membrane to membrane docking GO:0022614 14 6 0,000 0,04246357 0,1216278 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,04246357 0,12148317 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,04246357 0,12133889 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,04246357 0,12119496 ! receptor internalization GO:0031623 10 6 0,000 0,04246357 0,12105136 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,04246357 0,1209081 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,04246357 0,12076519 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,04246357 0,12062261 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,04246357 0,12048036 ! protein deubiquitination GO:0016579 14 6 0,000 0,04246357 0,12033845 ! protein destabilization GO:0031648 9 6 0,000 0,04246357 0,12019688 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,04246357 0,12005564 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,04246357 0,11991473 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,04246357 0,11977415 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,04246357 0,1196339 ! progesterone metabolic process GO:0042448 10 6 0,000 0,04246357 0,11949397 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,04246357 0,11935438 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,04246357 0,11921511 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,04246357 0,11907616 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,04246357 0,11893754 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,04246357 0,11879924 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,04246357 0,11866126 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,04246357 0,11852361 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,04246357 0,11838627 ! catecholamine transport GO:0051937 9 6 0,000 0,04246357 0,11824925 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,04246357 0,11811254 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,04246357 0,11797615 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,04246357 0,11784008 ! maternal placenta development GO:0001893 12 6 0,000 0,04246357 0,11770432 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,04246357 0,11756887 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,04246357 0,11743373 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,04246357 0,11729891 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,04246357 0,11716439 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,04246357 0,11703018 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,04246357 0,11689628 ! epidermal cell differentiation GO:0009913 68 46 1,000 0,04347313 0,11953869 ! pigmentation GO:0043473 100 46 1,000 0,04347313 0,11940223 ! response to insulin stimulus GO:0032868 95 46 1,000 0,04347313 0,11926608 ! endosome transport GO:0016197 108 47 1,000 0,04519474 0,123848 ! positive regulation of DNA binding GO:0043388 73 47 1,000 0,04519474 0,1237071 ! vascular process in circulatory system GO:0003018 80 47 1,000 0,04519474 0,12356653 ! JNK cascade GO:0007254 91 47 1,000 0,04519474 0,12342627 ! regulation of JNK cascade GO:0046328 94 47 1,000 0,04519474 0,12328633 ! protein homooligomerization GO:0051260 76 47 1,000 0,04519474 0,12314671 ! positive regulation of cell cycle GO:0045787 89 48 1,000 0,0469412 0,12776076 ! mitochondrial transport GO:0006839 82 48 1,000 0,0469412 0,1276164 ! Notch signaling pathway GO:0007219 96 48 1,000 0,0469412 0,12747237 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 1,000 0,0469412 0,12732865 ! regulation of action potential GO:0001508 95 49 1,000 0,04871206 0,13198334 ! regulation of protein complex disassembly GO:0043244 113 49 1,000 0,04871206 0,13183488 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 1,000 0,04871206 0,13168675 ! induction of apoptosis by extracellular signals GO:0008624 89 49 1,000 0,04871206 0,13153895 ! peptide metabolic process GO:0006518 76 49 1,000 0,04871206 0,13139149 ! unsaturated fatty acid metabolic process GO:0033559 86 49 1,000 0,04871206 0,13124435 ! endocrine system development GO:0035270 104 49 1,000 0,04871206 0,13109755 ! DNA-dependent DNA replication GO:0006261 74 49 1,000 0,04871206 0,13095107 ! immunoglobulin mediated immune response GO:0016064 83 49 1,000 0,04871206 0,13080492 GO:0019724|B cell mediated immunity, ! tRNA transcription GO:0009304 14 7 0,000 0,04936422 0,13240837 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,04936422 0,13226092 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,04936422 0,1321138 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,04936422 0,13196701 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,04936422 0,13182054 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,04936422 0,1316744 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,04936422 0,13152858 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,04936422 0,13138308 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,04936422 0,13123791 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,04936422 0,13109305 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,04936422 0,13094852 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,04936422 0,1308043 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,04936422 0,1306604 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,04936422 0,13051682 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 0,04936422 0,13037355 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,04936422 0,1302306 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,04936422 0,13008796 ! glycolipid transport GO:0046836 10 7 0,000 0,04936422 0,12994563 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,04936422 0,12980361 GO:0051923|sulfation, ! neuron adhesion GO:0007158 12 7 0,000 0,04936422 0,12966191 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,04936422 0,12952051 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,04936422 0,12937942 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,04936422 0,12923864 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,04936422 0,12909816 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,04936422 0,12895799 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,04936422 0,12881812 ! pericardium development GO:0060039 14 7 0,000 0,04936422 0,12867856 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,04936422 0,12853929 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,04936422 0,12840033 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,04936422 0,12826167 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,04936422 0,12812331 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,04936422 0,12798524 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,04936422 0,12784748 ! lipoprotein transport GO:0042953 14 7 0,000 0,04936422 0,12771001 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,04936422 0,12757283 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,04936422 0,12743595 ! rhythmic behavior GO:0007622 15 7 0,000 0,04936422 0,12729936 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,04936422 0,12716307 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,04936422 0,12702707 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,04936422 0,12689135 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,04936422 0,12675593 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,04936422 0,1266208 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,04936422 0,12648595 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,04936422 0,12635139 ! mechanosensory behavior GO:0007638 14 7 0,000 0,04936422 0,12621712 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,04936422 0,12608313 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,04936422 0,12594942 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,04936422 0,125816 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,04936422 0,12568286 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,04936422 0,12555001 ! spinal cord patterning GO:0021511 13 7 0,000 0,04936422 0,12541743 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,04936422 0,12528513 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,04936422 0,12515312 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,04936422 0,12502138 ! adrenal gland development GO:0030325 17 7 0,000 0,04936422 0,12488991 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,04936422 0,12475873 ! ovulation GO:0030728 9 7 0,000 0,04936422 0,12462781 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,04936422 0,12449718 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,04936422 0,12436681 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,04936422 0,12423672 ! microtubule nucleation GO:0007020 20 7 0,000 0,04936422 0,1241069 ! proline biosynthetic process GO:0006561 10 7 0,000 0,04936422 0,12397736 ! thyroid hormone generation GO:0006590 13 7 0,000 0,04936422 0,12384808 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,04936422 0,12371907 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,04936422 0,12359033 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,04936422 0,12346186 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,04936422 0,12333365 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,04936422 0,12320571 ! galactose metabolic process GO:0006012 13 7 0,000 0,04936422 0,12307804 ! vesicle fusion GO:0006906 17 7 0,000 0,04936422 0,12295063 ! response to dietary excess GO:0002021 8 7 0,000 0,04936422 0,12282348 ! intracellular pH reduction GO:0051452 11 7 0,000 0,04936422 0,1226966 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,04936422 0,12256998 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,04936422 0,12244361 ! organ growth GO:0035265 15 7 0,000 0,04936422 0,12231751 ! purine salvage GO:0043101 10 7 0,000 0,04936422 0,12219167 ! nucleoside transport GO:0015858 8 7 0,000 0,04936422 0,12206609 ! parturition GO:0007567 14 7 0,000 0,04936422 0,12194077 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,04936422 0,1218157 ! rRNA modification GO:0000154 14 7 0,000 0,04936422 0,12169089 ! spindle checkpoint GO:0031577 15 7 0,000 0,04936422 0,12156633 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,04936422 0,12144203 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,04936422 0,12131798 ! macrophage differentiation GO:0030225 11 7 0,000 0,04936422 0,12119419 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,04936422 0,12107065 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,04936422 0,12094736 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,04936422 0,12082432 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,04936422 0,12070153 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,04936422 0,12057899 ! fibrinolysis GO:0042730 10 7 0,000 0,04936422 0,1204567 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,04936422 0,12033466 ! eating behavior GO:0042755 7 7 0,000 0,04936422 0,12021286 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,04936422 0,12009131 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,04936422 0,11997001 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,04936422 0,11984895 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,04936422 0,11972813 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,04936422 0,11960756 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,04936422 0,11948723 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,04936422 0,11936714 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,04936422 0,1192473 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,04936422 0,11912769 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,04936422 0,11900832 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,04936422 0,1188892 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,04936422 0,11877031 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,04936422 0,11865165 ! regulation of meiosis GO:0040020 12 7 0,000 0,04936422 0,11853324 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,04936422 0,11841506 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,04936422 0,11829712 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,04936422 0,11817941 ! oxygen homeostasis GO:0032364 12 7 0,000 0,04936422 0,11806193 ! transcription termination GO:0006353 13 7 0,000 0,04936422 0,11794469 ! regulation of respiratory burst GO:0060263 11 7 0,000 0,04936422 0,11782768 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,04936422 0,11771091 ! anaphase GO:0051322 17 7 0,000 0,04936422 0,11759436 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,04936422 0,11747805 ! axonal fasciculation GO:0007413 18 7 0,000 0,04936422 0,11736196 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,04936422 0,11724611 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,04936422 0,11713048 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,04936422 0,11701508 ! diuresis GO:0030146 12 7 0,000 0,04936422 0,11689991 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,04936422 0,11678496 ! thiamin metabolic process GO:0006772 7 7 0,000 0,04936422 0,11667024 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,04936422 0,11655575 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,04936422 0,11644148 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,04936422 0,11632743 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,04936422 0,11621361 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,04936422 0,11610001 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,04936422 0,11598663 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,04936422 0,11587347 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,04936422 0,11576053 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,04936422 0,11564782 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,04936422 0,11553532 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,04936422 0,11542304 ! lymph node development GO:0048535 10 7 0,000 0,04936422 0,11531098 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,04936422 0,11519913 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,04936422 0,11508751 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,04936422 0,1149761 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,04936422 0,1148649 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,04936422 0,11475392 ! adult feeding behavior GO:0008343 9 7 0,000 0,04936422 0,11464315 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,04936422 0,1145326 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,04936422 0,11442226 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,04936422 0,11431213 ! muscle adaptation GO:0043500 14 7 0,000 0,04936422 0,11420222 ! embryonic heart tube development GO:0035050 10 7 0,000 0,04936422 0,11409251 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,04936422 0,11398302 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,04936422 0,11387374 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,04936422 0,11376466 ! protein prenylation GO:0018342 18 7 0,000 0,04936422 0,1136558 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,04936422 0,11354714 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,04936422 0,11343869 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,04936422 0,11333045 ! regulation of cell projection organization GO:0031344 121 50 1,000 0,05050688 0,11584325 ! positive regulation of binding GO:0051099 78 51 1,000 0,05232525 0,11989956 ! vesicle organization GO:0016050 107 51 1,000 0,05232525 0,11978548 ! regulation of cell shape GO:0008360 125 51 1,000 0,05232525 0,11967162 ! regulation of angiogenesis GO:0045765 114 52 1,000 0,05416671 0,12376553 ! cartilage development GO:0051216 90 52 1,000 0,05416671 0,12364811 ! synapse organization GO:0050808 85 52 1,000 0,05416671 0,12353091 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 1,000 0,05603086 0,12766121 ! cell maturation GO:0048469 100 53 1,000 0,05603086 0,12754044 ! regulation of neuron apoptosis GO:0043523 100 53 1,000 0,05603086 0,12741989 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,05621536 0,12771875 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,05621536 0,12759826 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,05621536 0,127478 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,05621536 0,12735797 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,05621536 0,12723816 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,05621536 0,12711857 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,05621536 0,12699921 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,05621536 0,12688008 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,05621536 0,12676116 ! meiotic prophase I GO:0007128 13 8 0,000 0,05621536 0,12664247 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,05621536 0,126524 ! oligopeptide transport GO:0006857 15 8 0,000 0,05621536 0,12640576 ! UTP metabolic process GO:0046051 8 8 0,000 0,05621536 0,12628773 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,05621536 0,12616993 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,05621536 0,12605234 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,05621536 0,12593497 ! succinate metabolic process GO:0006105 14 8 0,000 0,05621536 0,12581782 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,05621536 0,12570089 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,05621536 0,12558418 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,05621536 0,12546768 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,05621536 0,1253514 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,05621536 0,12523533 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,05621536 0,12511948 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,05621536 0,12500385 ! reflex GO:0060004 16 8 0,000 0,05621536 0,12488842 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,05621536 0,12477321 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,05621536 0,12465821 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,05621536 0,12454343 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,05621536 0,12442885 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,05621536 0,12431449 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,05621536 0,12420033 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,05621536 0,12408639 ! pigment granule organization GO:0048753 16 8 0,000 0,05621536 0,12397265 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,05621536 0,12385912 ! astrocyte differentiation GO:0048708 18 8 0,000 0,05621536 0,1237458 ! histidine metabolic process GO:0006547 16 8 0,000 0,05621536 0,12363269 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,05621536 0,12351978 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,05621536 0,12340708 ! glycine catabolic process GO:0006546 13 8 0,000 0,05621536 0,12329459 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,05621536 0,1231823 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,05621536 0,12307021 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,05621536 0,12295833 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,05621536 0,12284665 ! melanin metabolic process GO:0006582 15 8 0,000 0,05621536 0,12273517 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,05621536 0,1226239 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,05621536 0,12251283 ! macrophage activation GO:0042116 12 8 0,000 0,05621536 0,12240196 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,05621536 0,12229128 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,05621536 0,12218081 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,05621536 0,12207054 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,05621536 0,12196047 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,05621536 0,1218506 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,05621536 0,12174092 ! osteoblast development GO:0002076 16 8 0,000 0,05621536 0,12163144 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,05621536 0,12152216 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,05621536 0,12141307 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,05621536 0,12130418 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,05621536 0,12119548 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,05621536 0,12108698 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,05621536 0,12097868 ! response to UV-B GO:0010224 16 8 0,000 0,05621536 0,12087056 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,05621536 0,12076264 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,05621536 0,12065492 ! intermediate filament organization GO:0045109 12 8 0,000 0,05621536 0,12054738 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,05621536 0,12044004 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,05621536 0,12033288 ! cellular extravasation GO:0045123 12 8 0,000 0,05621536 0,12022592 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,05621536 0,12011915 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,05621536 0,12001256 ! response to antibiotic GO:0046677 11 8 0,000 0,05621536 0,11990617 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,05621536 0,11979996 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,05621536 0,11969395 ! DNA topological change GO:0006265 12 8 0,000 0,05621536 0,11958812 ! response to tropane GO:0014073 15 8 0,000 0,05621536 0,11948247 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,05621536 0,11937702 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,05621536 0,11927175 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,05621536 0,11916666 ! mast cell activation GO:0045576 14 8 0,000 0,05621536 0,11906176 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,05621536 0,11895705 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,05621536 0,11885251 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,05621536 0,11874817 ! nucleosome disassembly GO:0006337 14 8 0,000 0,05621536 0,118644 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,05621536 0,11854002 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,05621536 0,11843622 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,05621536 0,1183326 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,05621536 0,11822916 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,05621536 0,1181259 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,05621536 0,11802283 ! intracellular lipid transport GO:0032365 13 8 0,000 0,05621536 0,11791993 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,05621536 0,11781721 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,05621536 0,11771467 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,05621536 0,11761231 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,05621536 0,11751013 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,05621536 0,11740813 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,05621536 0,1173063 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,05621536 0,11720465 ! hormone catabolic process GO:0042447 17 8 0,000 0,05621536 0,11710317 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,05621536 0,11700187 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,05621536 0,11690074 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,05621536 0,11679979 ! ATP catabolic process GO:0006200 11 8 0,000 0,05621536 0,11669902 ! blastocyst growth GO:0001832 19 8 0,000 0,05621536 0,11659841 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,05621536 0,11649798 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,05621536 0,11639773 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,05621536 0,11629764 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,05621536 0,11619773 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,05621536 0,11609799 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,05621536 0,11599842 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,05621536 0,11589902 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,05621536 0,11579979 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,05621536 0,11570074 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,05621536 0,11560185 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,05621536 0,11550313 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,05621536 0,11540457 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,05621536 0,11530619 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,05621536 0,11520797 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,05621536 0,11510992 GO:0000076|DNA replication checkpoint, ! NAD biosynthetic process GO:0009435 13 8 0,000 0,05621536 0,11501204 ! activation of phospholipase C activity GO:0007202 103 54 1,000 0,05791726 0,11839332 GO:0010863|positive regulation of phospholipase C activity, ! negative regulation of cytoskeleton organization GO:0051494 124 54 1,000 0,05791726 0,11829282 ! glucose catabolic process GO:0006007 82 55 1,000 0,05982552 0,12208668 ! positive regulation of phospholipase activity GO:0010518 104 55 1,000 0,05982552 0,12198322 ! regulation of protein catabolic process GO:0042176 116 55 1,000 0,05982552 0,12187993 ! heart morphogenesis GO:0003007 97 55 1,000 0,05982552 0,12177682 ! sensory perception of smell GO:0007608 80 56 1,000 0,06175521 0,12559851 ! skeletal muscle fiber development GO:0048741 111 56 1,000 0,06175521 0,12549243 ! nucleotide-excision repair GO:0006289 83 56 1,000 0,06175521 0,12538653 ! regulation of developmental growth GO:0048638 15 9 0,000 0,06301736 0,12784128 ! axon extension GO:0048675 15 9 0,000 0,06301736 0,12773358 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,06301736 0,12762606 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,06301736 0,12751872 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,06301736 0,12741156 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,06301736 0,12730458 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,06301736 0,12719779 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,06301736 0,12709117 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,06301736 0,12698472 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,06301736 0,12687846 ! phosphate transport GO:0006817 19 9 0,000 0,06301736 0,12677237 ! reproductive behavior GO:0019098 19 9 0,000 0,06301736 0,12666647 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,06301736 0,12656073 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,06301736 0,12645518 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,06301736 0,1263498 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,06301736 0,1262446 ! GTP metabolic process GO:0046039 9 9 0,000 0,06301736 0,12613957 ! RNA methylation GO:0001510 15 9 0,000 0,06301736 0,12603471 ! elastic fiber assembly GO:0048251 15 9 0,000 0,06301736 0,12593003 ! artery development GO:0060840 24 9 0,000 0,06301736 0,12582553 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,06301736 0,12572119 ! regulation of glycolysis GO:0006110 21 9 0,000 0,06301736 0,12561703 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,06301736 0,12551305 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,06301736 0,12540923 ! chemosensory behavior GO:0007635 20 9 0,000 0,06301736 0,12530559 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,06301736 0,12520211 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,06301736 0,12509881 ! leukocyte degranulation GO:0043299 16 9 0,000 0,06301736 0,12499568 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,06301736 0,12489272 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,06301736 0,12478993 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,06301736 0,1246873 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,06301736 0,12458485 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,06301736 0,12448256 ! protein targeting to ER GO:0045047 22 9 0,000 0,06301736 0,12438044 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,06301736 0,12427849 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,06301736 0,12417671 ! T cell selection GO:0045058 23 9 0,000 0,06301736 0,12407509 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,06301736 0,12397364 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,06301736 0,12387235 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,06301736 0,12377123 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,06301736 0,12367028 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,06301736 0,12356949 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,06301736 0,12346886 ! mannose metabolic process GO:0006013 13 9 0,000 0,06301736 0,1233684 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,06301736 0,1232681 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,06301736 0,12316796 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,06301736 0,12306799 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,06301736 0,12296818 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,06301736 0,12286853 ! ruffle organization GO:0031529 15 9 0,000 0,06301736 0,12276904 ! retinol metabolic process GO:0042572 18 9 0,000 0,06301736 0,12266971 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,06301736 0,12257054 ! behavioral fear response GO:0001662 22 9 0,000 0,06301736 0,12247154 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,06301736 0,12237269 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,06301736 0,122274 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,06301736 0,12217547 GO:0030204|chondroitin sulfate metabolic process, ! protein heterooligomerization GO:0051291 16 9 0,000 0,06301736 0,1220771 ! oligodendrocyte development GO:0014003 10 9 0,000 0,06301736 0,12197889 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,06301736 0,12188084 ! segment specification GO:0007379 13 9 0,000 0,06301736 0,12178294 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,06301736 0,1216852 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,06301736 0,12158762 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,06301736 0,12149019 ! response to amine stimulus GO:0014075 13 9 0,000 0,06301736 0,12139292 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,06301736 0,12129581 ! erythrocyte development GO:0048821 15 9 0,000 0,06301736 0,12119885 ! gas homeostasis GO:0033483 16 9 0,000 0,06301736 0,12110205 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,06301736 0,1210054 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,06301736 0,1209089 ! renal water homeostasis GO:0003091 14 9 0,000 0,06301736 0,12081256 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,06301736 0,12071637 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,06301736 0,12062033 ! icosanoid secretion GO:0032309 15 9 0,000 0,06301736 0,12052445 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,06301736 0,12042872 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,06301736 0,12033314 GO:0021696|cerebellar cortex morphogenesis, ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,06301736 0,12023772 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,06301736 0,12014244 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,06301736 0,12004732 ! sterol catabolic process GO:0016127 11 9 0,000 0,06301736 0,11995234 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,06301736 0,11985752 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,06301736 0,11976284 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,06301736 0,11966832 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,06301736 0,11957394 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,06301736 0,11947972 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,06301736 0,11938564 ! musculoskeletal movement GO:0050881 14 9 0,000 0,06301736 0,11929171 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,06301736 0,11919792 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,06301736 0,11910429 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,06301736 0,1190108 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,06301736 0,11891746 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,06301736 0,11882426 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,06301736 0,11873121 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,06301736 0,11863831 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,06301736 0,11854555 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,06301736 0,11845294 ! mitochondrion localization GO:0051646 15 9 0,000 0,06301736 0,11836047 ! regulation of bone remodeling GO:0046850 137 57 1,000 0,06370593 0,11956043 ! muscle fiber development GO:0048747 112 57 1,000 0,06370593 0,11946725 ! lipid modification GO:0030258 97 57 1,000 0,06370593 0,1193742 ! regulation of phospholipase activity GO:0010517 106 57 1,000 0,06370593 0,11928131 ! regulation of tissue remodeling GO:0034103 140 58 1,000 0,06567729 0,1228768 ! regulation of endocytosis GO:0030100 91 58 1,000 0,06567729 0,12278132 ! adult behavior GO:0030534 99 58 1,000 0,06567729 0,122686 ! positive regulation of lipase activity GO:0060193 108 58 1,000 0,06567729 0,12259082 ! skeletal system morphogenesis GO:0048705 105 59 1,000 0,06766889 0,12621034 ! cytokine-mediated signaling pathway GO:0019221 97 59 1,000 0,06766889 0,12611258 ! integrin-mediated signaling pathway GO:0007229 135 59 1,000 0,06766889 0,12601497 ! establishment of organelle localization GO:0051656 109 59 1,000 0,06766889 0,12591751 ! camera-type eye development GO:0043010 116 60 1,000 0,06968033 0,12956018 ! kidney development GO:0001822 122 60 1,000 0,06968033 0,12946013 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,06977055 0,12952774 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,06977055 0,12942787 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,06977055 0,12932816 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,06977055 0,1292286 ! synapsis GO:0007129 13 10 0,000 0,06977055 0,12912919 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,06977055 0,12902994 ! N-glycan processing GO:0006491 20 10 0,000 0,06977055 0,12893084 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,06977055 0,12883189 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,06977055 0,12873309 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,06977055 0,12863444 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,06977055 0,12853595 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,06977055 0,12843761 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,06977055 0,12833941 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,06977055 0,12824137 ! androgen metabolic process GO:0008209 17 10 0,000 0,06977055 0,12814347 ! phospholipid efflux GO:0033700 16 10 0,000 0,06977055 0,12804573 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,06977055 0,12794813 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,06977055 0,12785069 ! pathogenesis GO:0009405 13 10 0,000 0,06977055 0,12775339 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,06977055 0,12765624 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,06977055 0,12755923 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,06977055 0,12746238 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,06977055 0,12736567 ! endoderm development GO:0007492 16 10 0,000 0,06977055 0,12726911 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,06977055 0,12717269 ! arginine catabolic process GO:0006527 13 10 0,000 0,06977055 0,12707642 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,06977055 0,1269803 ! proline metabolic process GO:0006560 13 10 0,000 0,06977055 0,12688432 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,06977055 0,12678848 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,06977055 0,12669279 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,06977055 0,12659725 ! V(D)J recombination GO:0033151 28 10 0,000 0,06977055 0,12650185 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,06977055 0,12640659 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,06977055 0,12631148 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,06977055 0,1262165 ! B cell proliferation GO:0042100 18 10 0,000 0,06977055 0,12612168 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,06977055 0,12602699 ! multicellular organism growth GO:0035264 18 10 0,000 0,06977055 0,12593245 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,06977055 0,12583804 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,06977055 0,12574378 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,06977055 0,12564966 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,06977055 0,12555568 ! macroautophagy GO:0016236 17 10 0,000 0,06977055 0,12546185 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,06977055 0,12536815 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,06977055 0,12527459 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,06977055 0,12518117 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,06977055 0,12508789 ! copper ion homeostasis GO:0055070 13 10 0,000 0,06977055 0,12499475 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,06977055 0,12490175 GO:0045685|regulation of glial cell differentiation, ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,06977055 0,12480889 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,06977055 0,12471616 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,06977055 0,12462357 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,06977055 0,12453112 ! blastoderm segmentation GO:0007350 18 10 0,000 0,06977055 0,12443881 ! response to dsRNA GO:0043331 20 10 0,000 0,06977055 0,12434663 ! DNA ligation GO:0006266 19 10 0,000 0,06977055 0,12425459 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,06977055 0,12416269 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,06977055 0,12407092 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,06977055 0,12397928 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,06977055 0,12388779 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,06977055 0,12379642 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,06977055 0,1237052 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,06977055 0,1236141 ! mRNA cleavage GO:0006379 17 10 0,000 0,06977055 0,12352314 ! protein sumoylation GO:0016925 15 10 0,000 0,06977055 0,12343232 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,06977055 0,12334162 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,06977055 0,12325107 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,06977055 0,12316064 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,06977055 0,12307035 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,06977055 0,12298018 ! salivary gland development GO:0007431 27 10 0,000 0,06977055 0,12289015 ! prophase GO:0051324 15 10 0,000 0,06977055 0,12280026 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,06977055 0,12271049 ! apical protein localization GO:0045176 15 10 0,000 0,06977055 0,12262086 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,06977055 0,12253135 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,06977055 0,12244198 ! midbrain development GO:0030901 13 10 0,000 0,06977055 0,12235273 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,06977055 0,12226362 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,06977055 0,12217464 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,06977055 0,12208578 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,06977055 0,12199706 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,06977055 0,12190846 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,06977055 0,12181999 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 0,06977055 0,12173165 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 0,06977055 0,12164344 ! oocyte development GO:0048599 17 10 0,000 0,06977055 0,12155536 ! blastocyst formation GO:0001825 17 10 0,000 0,06977055 0,1214674 ! cerebellar cortex development GO:0021695 15 10 0,000 0,06977055 0,12137957 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,06977055 0,12129187 ! activation of innate immune response GO:0002218 12 10 0,000 0,06977055 0,1212043 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,06977055 0,12111685 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,06977055 0,12102952 ! response to nicotine GO:0035094 20 10 0,000 0,06977055 0,12094233 ! establishment of cell polarity GO:0030010 16 10 0,000 0,06977055 0,12085526 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,06977055 0,12076831 ! response to peptide hormone stimulus GO:0043434 122 61 1,000 0,07171123 0,12403826 ! regulation of homeostatic process GO:0032844 134 62 1,000 0,07376121 0,12749244 ! nucleoside monophosphate metabolic process GO:0009123 107 63 1,000 0,07582989 0,13097396 ! regulation of lipid metabolic process GO:0019216 115 63 1,000 0,07582989 0,13088 ! steroid hormone receptor signaling pathway GO:0030518 129 63 1,000 0,07582989 0,13078618 ! respiratory burst GO:0045730 17 11 0,000 0,0764753 0,13180485 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,0764753 0,1317105 ! telencephalon cell migration GO:0022029 20 11 0,000 0,0764753 0,13161629 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,0764753 0,13152221 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,0764753 0,13142826 ! thyroid gland development GO:0030878 26 11 0,000 0,0764753 0,13133445 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,0764753 0,13124078 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,0764753 0,13114723 ! response to pain GO:0048265 24 11 0,000 0,0764753 0,13105382 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,0764753 0,13096055 ! T cell proliferation GO:0042098 26 11 0,000 0,0764753 0,1308674 ! bone resorption GO:0045453 16 11 0,000 0,0764753 0,13077439 ! ventral spinal cord development GO:0021517 21 11 0,000 0,0764753 0,13068151 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,0764753 0,13058876 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,0764753 0,13049615 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,0764753 0,13040366 ! melanocyte differentiation GO:0030318 21 11 0,000 0,0764753 0,13031131 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,0764753 0,13021909 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,0764753 0,13012699 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,0764753 0,13003503 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,0764753 0,1299432 GO:0043088|regulation of Cdc42 GTPase activity, ! lipid digestion GO:0044241 18 11 0,000 0,0764753 0,1298515 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,0764753 0,12975992 ! UV protection GO:0009650 19 11 0,000 0,0764753 0,12966848 ! adult heart development GO:0007512 14 11 0,000 0,0764753 0,12957716 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,0764753 0,12948597 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,0764753 0,12939492 ! temperature homeostasis GO:0001659 17 11 0,000 0,0764753 0,12930398 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,0764753 0,12921318 ! negative regulation of ossification GO:0030279 26 11 0,000 0,0764753 0,12912251 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,0764753 0,12903196 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,0764753 0,12894153 ! regulation of organ growth GO:0046620 13 11 0,000 0,0764753 0,12885124 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,0764753 0,12876107 ! vasoconstriction GO:0042310 18 11 0,000 0,0764753 0,12867103 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,0764753 0,12858111 ! embryonic axis specification GO:0000578 18 11 0,000 0,0764753 0,12849132 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,0764753 0,12840165 ! snRNA metabolic process GO:0016073 24 11 0,000 0,0764753 0,12831211 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,0764753 0,1282227 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,0764753 0,12813341 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,0764753 0,12804424 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,0764753 0,12795519 ! zymogen activation GO:0031638 15 11 0,000 0,0764753 0,12786627 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,0764753 0,12777748 ! neuroblast proliferation GO:0007405 24 11 0,000 0,0764753 0,12768881 ! nucleosome positioning GO:0016584 15 11 0,000 0,0764753 0,12760026 ! regulation of isotype switching GO:0045191 22 11 0,000 0,0764753 0,12751183 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,0764753 0,12742352 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,0764753 0,12733534 ! acid secretion GO:0046717 18 11 0,000 0,0764753 0,12724728 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,0764753 0,12715934 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,0764753 0,12707153 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,0764753 0,12698383 ! oocyte differentiation GO:0009994 18 11 0,000 0,0764753 0,12689625 ! thymus development GO:0048538 27 11 0,000 0,0764753 0,1268088 ! cholesterol efflux GO:0033344 19 11 0,000 0,0764753 0,12672147 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,0764753 0,12663425 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,0764753 0,12654716 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,0764753 0,12646019 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,0764753 0,12637333 ! embryonic gut development GO:0048566 15 11 0,000 0,0764753 0,1262866 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,0764753 0,12619998 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,0764753 0,12611348 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,0764753 0,1260271 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,0764753 0,12594084 ! defense response to fungus GO:0050832 13 11 0,000 0,0764753 0,1258547 ! developmental induction GO:0031128 19 11 0,000 0,0764753 0,12576867 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,0764753 0,12568277 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,0764753 0,12559698 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,0764753 0,1255113 ! sequestering of metal ion GO:0051238 14 11 0,000 0,0764753 0,12542575 ! lamellipodium assembly GO:0030032 20 11 0,000 0,0764753 0,12534031 ! regulation of embryonic development GO:0045995 27 11 0,000 0,0764753 0,12525498 ! nucleus localization GO:0051647 19 11 0,000 0,0764753 0,12516978 ! regulation of synapse organization GO:0050807 17 11 0,000 0,0764753 0,12508468 ! lymphocyte mediated immunity GO:0002449 114 64 1,000 0,0779169 0,12735603 ! embryonic limb morphogenesis GO:0030326 125 65 1,000 0,08002187 0,13070783 GO:0035113|embryonic appendage morphogenesis, ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 1,000 0,08214444 0,1340838 ! fatty acid biosynthetic process GO:0006633 124 66 1,000 0,08214444 0,13399289 ! secondary metabolic process GO:0019748 116 66 1,000 0,08214444 0,13390211 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,08313194 0,13542007 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,08313194 0,13532845 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,08313194 0,13523695 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 0,08313194 0,13514557 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,08313194 0,13505432 ! virus-host interaction GO:0019048 29 12 0,000 0,08313194 0,13496319 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,08313194 0,13487218 ! mating GO:0007618 17 12 0,000 0,08313194 0,1347813 ! protein complex disassembly GO:0043241 27 12 0,000 0,08313194 0,13469054 GO:0043624|cellular protein complex disassembly, ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,08313194 0,1345999 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,08313194 0,13450938 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,08313194 0,13441899 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,08313194 0,13432871 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,08313194 0,13423856 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,08313194 0,13414852 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,08313194 0,13405861 ! drug transport GO:0015893 16 12 0,000 0,08313194 0,13396882 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,08313194 0,13387915 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,08313194 0,1337896 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,08313194 0,13370017 ! polyamine metabolic process GO:0006595 17 12 0,000 0,08313194 0,13361086 ! mitotic spindle organization GO:0007052 21 12 0,000 0,08313194 0,13352166 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,08313194 0,13343259 ! forebrain cell migration GO:0021885 21 12 0,000 0,08313194 0,13334363 ! asymmetric protein localization GO:0008105 20 12 0,000 0,08313194 0,1332548 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,08313194 0,13316608 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,08313194 0,13307748 ! entry into host cell GO:0030260 32 12 0,000 0,08313194 0,132989 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,08313194 0,13290063 ! monoamine transport GO:0015844 18 12 0,000 0,08313194 0,13281238 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,08313194 0,13272425 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,08313194 0,13263624 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,08313194 0,13254834 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,08313194 0,13246056 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,08313194 0,1323729 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,08313194 0,13228535 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,08313194 0,13219792 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,08313194 0,1321106 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,08313194 0,1320234 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,08313194 0,13193631 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,08313194 0,13184934 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,08313194 0,13176248 ! cranial nerve development GO:0021545 20 12 0,000 0,08313194 0,13167574 ! fucose catabolic process GO:0019317 22 12 0,000 0,08313194 0,13158911 GO:0042355|L-fucose catabolic process, ! histone methylation GO:0016571 26 12 0,000 0,08313194 0,1315026 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,08313194 0,1314162 ! autonomic nervous system development GO:0048483 24 12 0,000 0,08313194 0,13132991 ! gland morphogenesis GO:0022612 29 12 0,000 0,08313194 0,13124373 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,08313194 0,13115767 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,08313194 0,13107172 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,08313194 0,13098589 ! spleen development GO:0048536 22 12 0,000 0,08313194 0,13090016 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,08313194 0,13081455 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,08313194 0,13072905 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,08313194 0,13064366 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,08313194 0,13055839 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,08313194 0,13047322 ! response to cold GO:0009409 17 12 0,000 0,08313194 0,13038817 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,08313194 0,13030322 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,08313194 0,13021839 ! regulation of cellular response to stress GO:0080135 128 67 1,000 0,08428424 0,13193746 ! activation of MAPK activity GO:0000187 115 67 1,000 0,08428424 0,13185168 ! homeostasis of number of cells GO:0048872 114 67 1,000 0,08428424 0,131766 ! hexose catabolic process GO:0019320 104 67 1,000 0,08428424 0,13168044 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 1,000 0,08428424 0,13159499 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 1,000 0,08644092 0,13487474 ! regulation of lipase activity GO:0060191 130 68 1,000 0,08644092 0,13478733 ! protein maturation by peptide bond cleavage GO:0051605 105 68 1,000 0,08644092 0,13470003 ! cAMP-mediated signaling GO:0019933 120 69 1,000 0,08861413 0,13799715 ! cGMP metabolic process GO:0046068 18 13 0,000 0,08974082 0,13966133 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,08974082 0,13957105 ! regulation of chemokine production GO:0032642 18 13 0,000 0,08974082 0,13948089 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,08974082 0,13939084 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,08974082 0,13930091 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,08974082 0,1392111 ! lipid localization GO:0010876 28 13 0,000 0,08974082 0,1391214 GO:0019915|lipid storage, ! organelle fusion GO:0048284 32 13 0,000 0,08974082 0,13903182 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,08974082 0,13894235 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,08974082 0,138853 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,08974082 0,13876376 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,08974082 0,13867464 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,08974082 0,13858563 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,08974082 0,13849674 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,08974082 0,13840796 ! methionine metabolic process GO:0006555 27 13 0,000 0,08974082 0,13831929 ! plasma membrane organization GO:0007009 24 13 0,000 0,08974082 0,13823074 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,08974082 0,1381423 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,08974082 0,13805398 ! Golgi organization GO:0007030 24 13 0,000 0,08974082 0,13796576 ! cytokine metabolic process GO:0042107 22 13 0,000 0,08974082 0,13787766 ! exocrine system development GO:0035272 32 13 0,000 0,08974082 0,13778967 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 0,08974082 0,1377018 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,08974082 0,13761403 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,08974082 0,13752638 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,08974082 0,13743884 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,08974082 0,13735141 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,08974082 0,13726409 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,08974082 0,13717689 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,08974082 0,13708979 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,08974082 0,1370028 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,08974082 0,13691593 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,08974082 0,13682916 ! ribosome assembly GO:0042255 17 13 0,000 0,08974082 0,13674251 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,08974082 0,13665596 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,08974082 0,13656952 ! chromatin silencing GO:0006342 26 13 0,000 0,08974082 0,1364832 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,08974082 0,13639698 ! regulation of epidermis development GO:0045682 19 13 0,000 0,08974082 0,13631087 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,08974082 0,13622487 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,08974082 0,13613898 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,08974082 0,13605319 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,08974082 0,13596752 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,08974082 0,13588195 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,08974082 0,13579649 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,08974082 0,13571114 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,08974082 0,13562589 ! embryonic placenta development GO:0001892 23 13 0,000 0,08974082 0,13554075 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,08974082 0,13545572 ! insulin secretion GO:0030073 23 13 0,000 0,08974082 0,1353708 ! actin filament polymerization GO:0030041 24 13 0,000 0,08974082 0,13528598 ! acrosome reaction GO:0007340 18 13 0,000 0,08974082 0,13520126 ! appendage morphogenesis GO:0035107 135 70 1,000 0,09080352 0,13671668 GO:0035108|limb morphogenesis, ! appendage development GO:0048736 136 71 1,000 0,09300874 0,13994936 GO:0060173|limb development, ! regulation of MAPKKK cascade GO:0043408 142 71 1,000 0,09300874 0,13986189 ! rRNA transcription GO:0009303 25 14 0,000 0,09630228 0,14472411 ! lactation GO:0007595 26 14 0,000 0,09630228 0,14463377 ! reproductive cellular process GO:0048610 20 14 0,000 0,09630228 0,14454354 ! tRNA modification GO:0006400 20 14 0,000 0,09630228 0,14445343 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,09630228 0,14436342 ! regulation of S phase GO:0033261 23 14 0,000 0,09630228 0,14427353 ! water transport GO:0006833 21 14 0,000 0,09630228 0,14418376 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,09630228 0,14409409 ! non-recombinational repair GO:0000726 25 14 0,000 0,09630228 0,14400453 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,09630228 0,14391509 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,09630228 0,14382576 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,09630228 0,14373654 ! RNA polyadenylation GO:0043631 30 14 0,000 0,09630228 0,14364742 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,09630228 0,14355842 ! palate development GO:0060021 31 14 0,000 0,09630228 0,14346953 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,09630228 0,14338075 ! regulated secretory pathway GO:0045055 23 14 0,000 0,09630228 0,14329208 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,09630228 0,14320352 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,09630228 0,14311507 ! arginine metabolic process GO:0006525 17 14 0,000 0,09630228 0,14302673 ! regulation of heart rate GO:0002027 24 14 0,000 0,09630228 0,14293849 ! organic alcohol transport GO:0015850 29 14 0,000 0,09630228 0,14285037 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,09630228 0,14276235 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,09630228 0,14267444 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,09630228 0,14258664 ! neutral amino acid transport GO:0015804 26 14 0,000 0,09630228 0,14249895 ! L-amino acid transport GO:0015807 30 14 0,000 0,09630228 0,14241137 ! bone mineralization GO:0030282 17 14 0,000 0,09630228 0,14232389 ! stem cell development GO:0048864 43 14 0,000 0,09630228 0,14223652 GO:0019827|stem cell maintenance, ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,09630228 0,14214926 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,09630228 0,14206211 ! cerebellum development GO:0021549 21 14 0,000 0,09630228 0,14197506 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,09630228 0,14188812 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,09630228 0,14180128 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,09630228 0,14171455 ! cofactor transport GO:0051181 26 14 0,000 0,09630228 0,14162793 ! NADP metabolic process GO:0006739 24 14 0,000 0,09630228 0,14154141 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,09630228 0,141455 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,09630228 0,1413687 ! intestinal absorption GO:0050892 25 14 0,000 0,09630228 0,1412825 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,09630228 0,1411964 ! oxygen transport GO:0015671 21 14 0,000 0,09630228 0,14111041 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,09630228 0,14102453 ! male genitalia development GO:0030539 24 14 0,000 0,09630228 0,14093874 ! regulation of axon extension GO:0030516 37 14 0,000 0,09630228 0,14085307 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,09630228 0,14076749 ! axon guidance GO:0007411 139 73 1,000 0,09746535 0,14238108 ! meiosis GO:0007126 121 74 1,000 0,09971607 0,14558062 GO:0051327|M phase of meiotic cell cycle, ! leukocyte mediated immunity GO:0002443 128 74 1,000 0,09971607 0,14549233 ! organelle localization GO:0051640 136 74 1,000 0,09971607 0,14540416 ! phosphoinositide-mediated signaling GO:0048015 131 75 1,000 0,10198129 0,14861719 ! regulation of vesicle-mediated transport GO:0060627 119 75 1,000 0,10198129 0,14852723 ! meiotic cell cycle GO:0051321 122 75 1,000 0,10198129 0,14843738 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,10281666 0,14956281 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,10281666 0,14947244 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,10281666 0,14938218 ! superoxide anion generation GO:0042554 20 15 0,000 0,10281666 0,14929203 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,10281666 0,14920199 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,10281666 0,14911205 ! copper ion transport GO:0006825 20 15 0,000 0,10281666 0,14902223 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,10281666 0,14893251 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,10281666 0,1488429 ! sulfate transport GO:0008272 23 15 0,000 0,10281666 0,14875339 ! response to cAMP GO:0051591 22 15 0,000 0,10281666 0,148664 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,10281666 0,14857471 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,10281666 0,14848553 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,10281666 0,14839646 ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,10281666 0,14830749 ! response to hexose stimulus GO:0009746 22 15 0,000 0,10281666 0,14821863 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,10281666 0,14812988 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,10281666 0,14804123 ! pituitary gland development GO:0021983 29 15 0,000 0,10281666 0,14795269 ! vesicle coating GO:0006901 33 15 0,000 0,10281666 0,14786425 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,10281666 0,14777592 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,10281666 0,1476877 ! regulation of exocytosis GO:0017157 22 15 0,000 0,10281666 0,14759958 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,10281666 0,14751157 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,10281666 0,14742366 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,10281666 0,14733585 ! regulation of vasodilation GO:0042312 26 15 0,000 0,10281666 0,14724815 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,10281666 0,14716056 ! histone deacetylation GO:0016575 20 15 0,000 0,10281666 0,14707306 ! mRNA splice site selection GO:0006376 38 15 0,000 0,10281666 0,14698568 ! tissue regeneration GO:0042246 26 15 0,000 0,10281666 0,14689839 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,10281666 0,14681121 ! water homeostasis GO:0030104 27 15 0,000 0,10281666 0,14672414 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,10281666 0,14663716 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,10281666 0,14655029 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,10281666 0,14646353 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,10281666 0,14637686 ! heme biosynthetic process GO:0006783 29 15 0,000 0,10281666 0,1462903 ! cell killing GO:0001906 29 15 0,000 0,10281666 0,14620384 ! detection of bacterium GO:0016045 18 15 0,000 0,10281666 0,14611748 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,10281666 0,14603122 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,10281666 0,14594507 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,10281666 0,14585902 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,10281666 0,14577307 ! peptide hormone processing GO:0016486 23 15 0,000 0,10281666 0,14568722 ! monosaccharide catabolic process GO:0046365 115 76 1,000 0,10426069 0,14764639 ! regulation of catabolic process GO:0009894 161 76 1,000 0,10426069 0,14755954 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 0,10655395 0,15071653 ! neuropeptide signaling pathway GO:0007218 107 77 1,000 0,10655395 0,15062798 ! blood coagulation GO:0007596 146 78 1,000 0,10886076 0,15379859 GO:0050817|coagulation, ! negative regulation of organelle organization GO:0010639 161 78 1,000 0,10886076 0,15370833 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,1092843 0,15421585 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,1092843 0,15412546 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,1092843 0,15403517 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,1092843 0,15394498 ! bone remodeling GO:0046849 27 16 0,000 0,1092843 0,1538549 ! filopodium assembly GO:0046847 32 16 0,000 0,1092843 0,15376493 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,1092843 0,15367506 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,1092843 0,1535853 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,1092843 0,15349564 ! startle response GO:0001964 28 16 0,000 0,1092843 0,15340608 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,1092843 0,15331663 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,1092843 0,15322729 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,1092843 0,15313805 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,1092843 0,15304891 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,1092843 0,15295988 ! protein polyubiquitination GO:0000209 34 16 0,000 0,1092843 0,15287095 ! glutamate metabolic process GO:0006536 22 16 0,000 0,1092843 0,15278212 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,1092843 0,1526934 ! response to osmotic stress GO:0006970 25 16 0,000 0,1092843 0,15260478 ! lysosomal transport GO:0007041 26 16 0,000 0,1092843 0,15251626 ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,1092843 0,15242784 ! intermediate filament-based process GO:0045103 32 16 0,000 0,1092843 0,15233953 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,1092843 0,15225132 ! negative regulation of immune response GO:0050777 35 16 0,000 0,1092843 0,15216321 ! axon cargo transport GO:0008088 43 16 0,000 0,1092843 0,1520752 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,1092843 0,1519873 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,1092843 0,1518995 ! DNA replication initiation GO:0006270 27 16 0,000 0,1092843 0,15181179 ! neuron recognition GO:0008038 35 16 0,000 0,1092843 0,15172419 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,1092843 0,15163669 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,1092843 0,1515493 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,1092843 0,151462 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,1092843 0,1513748 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,1092843 0,1512877 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,1092843 0,15120071 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,1092843 0,15111381 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,1092843 0,15102701 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,1092843 0,15094031 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,1092843 0,15085372 ! defense response to virus GO:0051607 37 16 0,000 0,1092843 0,15076722 ! sensory perception of chemical stimulus GO:0007606 109 79 1,000 0,11118081 0,15329571 ! positive regulation of phosphorylation GO:0042327 129 79 1,000 0,11118081 0,15320791 ! regulation of adenylate cyclase activity GO:0045761 156 80 1,000 0,11351377 0,15633322 ! protein import into nucleus GO:0006606 158 80 1,000 0,11351377 0,15624379 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,11570553 0,15916952 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,11570553 0,15907857 ! metencephalon development GO:0022037 30 17 0,000 0,11570553 0,15898772 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,11570553 0,15889697 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,11570553 0,15880633 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,11570553 0,15871579 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,11570553 0,15862535 ! endothelial cell migration GO:0043542 28 17 0,000 0,11570553 0,15853502 ! inositol metabolic process GO:0006020 28 17 0,000 0,11570553 0,15844479 ! gene silencing by RNA GO:0031047 36 17 0,000 0,11570553 0,15835466 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,11570553 0,15826464 ! glial cell development GO:0021782 27 17 0,000 0,11570553 0,15817471 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,11570553 0,15808489 ! adult walking behavior GO:0007628 33 17 0,000 0,11570553 0,15799517 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,11570553 0,15790556 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,11570553 0,15781604 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,11570553 0,15772663 ! myoblast differentiation GO:0045445 45 17 0,000 0,11570553 0,15763731 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,11570553 0,1575481 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,11570553 0,15745899 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,11570553 0,15736998 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,11570553 0,15728107 ! glycine metabolic process GO:0006544 28 17 0,000 0,11570553 0,15719226 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,11570553 0,15710355 ! NAD metabolic process GO:0019674 29 17 0,000 0,11570553 0,15701494 ! membrane budding GO:0006900 37 17 0,000 0,11570553 0,15692644 ! DNA integration GO:0015074 29 17 0,000 0,11570553 0,15683803 ! regulation of protein binding GO:0043393 33 17 0,000 0,11570553 0,15674972 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,11570553 0,15666151 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,11570553 0,15657339 ! genitalia development GO:0048806 30 17 0,000 0,11570553 0,15648538 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,11570553 0,15639747 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,11570553 0,15630966 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,11570553 0,15622194 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,11570553 0,15613432 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,11570553 0,1560468 ! steroid catabolic process GO:0006706 31 17 0,000 0,11570553 0,15595938 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,11570553 0,15587206 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,11570553 0,15578483 ! gas transport GO:0015669 25 17 0,000 0,11570553 0,1556977 ! organic cation transport GO:0015695 31 17 0,000 0,11570553 0,15561067 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,11570553 0,15552374 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,11570553 0,1554369 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,11570553 0,15535017 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 1,000 0,11585936 0,15546995 GO:0045937|positive regulation of phosphate metabolic process, ! nuclear import GO:0051170 161 81 1,000 0,11585936 0,15538329 ! regulation of cAMP biosynthetic process GO:0030817 161 82 1,000 0,11821727 0,15845724 ! response to drug GO:0042493 143 82 1,000 0,11821727 0,15836901 ! regulation of cyclase activity GO:0031279 159 82 1,000 0,11821727 0,15828088 ! cellular response to hormone stimulus GO:0032870 167 82 1,000 0,11821727 0,15819285 ! regulation of lyase activity GO:0051339 160 83 1,000 0,1205872 0,16127449 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,12208067 0,16318117 ! neuron maturation GO:0042551 42 18 0,000 0,12208067 0,16309056 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,12208067 0,16300005 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,12208067 0,16290965 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,12208067 0,16281934 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,12208067 0,16272914 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,12208067 0,16263904 ! memory GO:0007613 31 18 0,000 0,12208067 0,16254903 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,12208067 0,16245912 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,12208067 0,16236932 ! patterning of blood vessels GO:0001569 39 18 0,000 0,12208067 0,16227961 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,12208067 0,16219 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,12208067 0,1621005 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,12208067 0,16201109 ! response to retinoic acid GO:0032526 26 18 0,000 0,12208067 0,16192177 ! response to fungus GO:0009620 21 18 0,000 0,12208067 0,16183256 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,12208067 0,16174345 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,12208067 0,16165443 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,12208067 0,16156551 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,12208067 0,16147669 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,12208067 0,16138797 ! vitamin transport GO:0051180 27 18 0,000 0,12208067 0,16129934 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,12208067 0,16121081 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,12208067 0,16112238 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,12208067 0,16103404 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,12208067 0,16094581 ! nerve development GO:0021675 28 18 0,000 0,12208067 0,16085767 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,12208067 0,16076962 ! regulation of cAMP metabolic process GO:0030814 168 84 1,000 0,12296886 0,1618507 ! hemostasis GO:0007599 158 84 1,000 0,12296886 0,16176221 ! positive regulation of cell activation GO:0050867 145 85 1,000 0,12536196 0,16482015 GO:0002696|positive regulation of leukocyte activation, ! protein secretion GO:0009306 39 19 0,000 0,12841007 0,16873546 ! positive regulation of translation GO:0045727 30 19 0,000 0,12841007 0,16864335 ! negative regulation of defense response GO:0031348 25 19 0,000 0,12841007 0,16855135 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,12841007 0,16845945 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,12841007 0,16836764 ! skin development GO:0043588 36 19 0,000 0,12841007 0,16827594 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,12841007 0,16818434 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,12841007 0,16809283 ! bile acid metabolic process GO:0008206 29 19 0,000 0,12841007 0,16800143 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,12841007 0,16791012 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,12841007 0,16781892 ! pigmentation during development GO:0048066 41 19 0,000 0,12841007 0,16772781 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,12841007 0,1676368 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,12841007 0,16754589 ! heme metabolic process GO:0042168 36 19 0,000 0,12841007 0,16745508 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,12841007 0,16736437 ! plasma membrane fusion GO:0045026 28 19 0,000 0,12841007 0,16727375 ! peptide cross-linking GO:0018149 37 19 0,000 0,12841007 0,16718324 ! protein export from nucleus GO:0006611 36 19 0,000 0,12841007 0,16709282 ! heart process GO:0003015 30 19 0,000 0,12841007 0,1670025 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,12841007 0,16691228 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,12841007 0,16682215 ! visual learning GO:0008542 36 19 0,000 0,12841007 0,16673212 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,12841007 0,16664219 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,12841007 0,16655236 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,12841007 0,16646262 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,12841007 0,16637298 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,12841007 0,16628344 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,12841007 0,16619399 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,12841007 0,16610464 ! peptide hormone secretion GO:0030072 31 19 0,000 0,12841007 0,16601538 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 1,000 0,13018134 0,16821498 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,13469404 0,17395269 ! positive regulation of ossification GO:0045778 47 20 0,000 0,13469404 0,17385937 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,13469404 0,17376615 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,13469404 0,17367302 ! cAMP metabolic process GO:0046058 36 20 0,000 0,13469404 0,17358 ! response to vitamin GO:0033273 31 20 0,000 0,13469404 0,17348708 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,13469404 0,17339426 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 0,13469404 0,17330153 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,13469404 0,17320891 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,13469404 0,17311638 ! response to alkaloid GO:0043279 38 20 0,000 0,13469404 0,17302395 ! retinoid metabolic process GO:0001523 32 20 0,000 0,13469404 0,17293162 GO:0016101|diterpenoid metabolic process, ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,13469404 0,17283939 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,13469404 0,17274726 GO:0032392|DNA geometric change, ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,13469404 0,17265523 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,13469404 0,17256329 ! body fluid secretion GO:0007589 31 20 0,000 0,13469404 0,17247145 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,13469404 0,17237971 ! peptide secretion GO:0002790 35 20 0,000 0,13469404 0,17228807 ! stem cell differentiation GO:0048863 53 20 0,000 0,13469404 0,17219653 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,13469404 0,17210508 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,13469404 0,17201373 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,13469404 0,17192247 ! sensory perception of pain GO:0019233 30 20 0,000 0,13469404 0,17183132 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,13469404 0,17174026 ! diencephalon development GO:0021536 34 20 0,000 0,13469404 0,17164929 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,13469404 0,17155842 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,13469404 0,17146765 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,13469404 0,17137698 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,13469404 0,1712864 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,13469404 0,17119591 ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,13469404 0,17110552 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,13469404 0,17101523 ! regulation of glucose import GO:0046324 29 20 0,000 0,13469404 0,17092503 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,13469404 0,17083493 ! actin filament-based movement GO:0030048 43 20 0,000 0,13469404 0,17074492 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,13469404 0,17065501 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,13469404 0,17056519 ! negative regulation of translation GO:0017148 29 20 0,000 0,13469404 0,17047547 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,13469404 0,17038584 ! regulation of cell morphogenesis GO:0022604 215 89 1,000 0,13504308 0,1707376 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 1,000 0,13748915 0,17373892 ! regulation of cell cycle process GO:0010564 149 90 1,000 0,13748915 0,17364772 ! regulation of cell killing GO:0031341 42 21 0,000 0,14093292 0,17790377 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,14093292 0,17781048 ! hormone secretion GO:0046879 38 21 0,000 0,14093292 0,17771729 ! glycerol metabolic process GO:0006071 34 21 0,000 0,14093292 0,1776242 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,14093292 0,1775312 ! ovarian follicle development GO:0001541 35 21 0,000 0,14093292 0,1774383 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,14093292 0,1773455 ! smooth muscle contraction GO:0006939 46 21 0,000 0,14093292 0,17725279 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,14093292 0,17716019 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,14093292 0,17706767 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,14093292 0,17697526 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,14093292 0,17688294 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,14093292 0,17679072 ! cytolysis GO:0019835 24 21 0,000 0,14093292 0,17669859 ! vasodilation GO:0042311 39 21 0,000 0,14093292 0,17660656 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,14093292 0,17651462 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,14093292 0,17642279 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,14093292 0,17633104 ! oogenesis GO:0048477 36 21 0,000 0,14093292 0,17623939 ! DNA modification GO:0006304 34 21 0,000 0,14093292 0,17614784 ! collagen fibril organization GO:0030199 59 21 0,000 0,14093292 0,17605638 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,14093292 0,17596502 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,14093292 0,17587375 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,14093292 0,17578258 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,14093292 0,1756915 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,14093292 0,17560052 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,14093292 0,17550962 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,14093292 0,17541883 ! collagen catabolic process GO:0030574 28 21 0,000 0,14093292 0,17532813 ! sperm-egg recognition GO:0035036 21 21 0,000 0,14093292 0,17523752 ! gut development GO:0048565 39 21 0,000 0,14093292 0,175147 ! regulation of nucleotide metabolic process GO:0006140 182 93 1,000 0,14488494 0,17996549 ! regulation of membrane potential GO:0042391 164 93 1,000 0,14488494 0,17987263 ! negative regulation of multicellular organismal process GO:0051241 166 93 1,000 0,14488494 0,17977987 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,14712701 0,18246783 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,14712701 0,18237382 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,14712701 0,18227991 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,14712701 0,1821861 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,14712701 0,18209238 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,14712701 0,18199876 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,14712701 0,18190524 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,14712701 0,18181181 ! regeneration GO:0031099 41 22 0,000 0,14712701 0,18171848 ! keratinization GO:0031424 28 22 0,000 0,14712701 0,18162524 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,14712701 0,1815321 ! sensory perception of taste GO:0050909 28 22 0,000 0,14712701 0,18143905 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,14712701 0,1813461 ! vacuolar transport GO:0007034 36 22 0,000 0,14712701 0,18125325 ! lysosome organization GO:0007040 41 22 0,000 0,14712701 0,18116049 ! central nervous system neuron development GO:0021954 46 22 0,000 0,14712701 0,18106782 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,14712701 0,18097525 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,14712701 0,18088278 ! fucose metabolic process GO:0006004 39 22 0,000 0,14712701 0,18079039 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,14712701 0,18069811 ! ureteric bud development GO:0001657 43 22 0,000 0,14712701 0,18060591 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,14712701 0,18051382 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,14712701 0,18042181 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,14712701 0,1803299 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,14712701 0,18023808 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,14712701 0,18014636 ! sarcomere organization GO:0045214 30 22 0,000 0,14712701 0,18005473 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,14712701 0,17996319 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,14712701 0,17987174 ! biogenic amine metabolic process GO:0006576 155 94 1,000 0,14736852 0,1800755 ! positive regulation of DNA replication GO:0045740 43 23 0,000 0,15327665 0,18719981 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,15327665 0,18710483 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,15327665 0,18700995 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,15327665 0,18691517 ! viral genome replication GO:0019079 41 23 0,000 0,15327665 0,18682048 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,15327665 0,18672589 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,15327665 0,18663139 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,15327665 0,18653699 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,15327665 0,18644268 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,15327665 0,18634847 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,15327665 0,18625436 ! visual behavior GO:0007632 42 23 0,000 0,15327665 0,18616034 ! response to ethanol GO:0045471 46 23 0,000 0,15327665 0,18606641 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,15327665 0,18597258 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,15327665 0,18587885 ! peroxisome organization GO:0007031 37 23 0,000 0,15327665 0,1857852 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,15327665 0,18569166 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,15327665 0,1855982 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,15327665 0,18550484 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,15327665 0,18541158 GO:0051693|actin filament capping, ! regulation of viral reproduction GO:0050792 38 23 0,000 0,15327665 0,18531841 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,15327665 0,18522533 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,15327665 0,18513234 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,15327665 0,18503945 ! fatty acid transport GO:0015908 44 23 0,000 0,15327665 0,18494665 ! platelet activation GO:0030168 37 23 0,000 0,15327665 0,18485395 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,15327665 0,18476134 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,15327665 0,18466882 ! hormone transport GO:0009914 40 23 0,000 0,15327665 0,18457639 ! cell-cell recognition GO:0009988 25 23 0,000 0,15327665 0,18448406 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,15327665 0,18439181 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,15327665 0,18429966 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,15327665 0,18420761 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,15327665 0,18411564 ! hormone metabolic process GO:0042445 157 97 1,000 0,15487062 0,18593748 ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,15938216 0,19125859 ! vesicle docking GO:0048278 47 24 0,000 0,15938216 0,19116324 ! spinal cord development GO:0021510 47 24 0,000 0,15938216 0,19106799 ! vacuole organization GO:0007033 43 24 0,000 0,15938216 0,19097284 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,15938216 0,19087778 ! digestive system process GO:0022600 39 24 0,000 0,15938216 0,19078282 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,15938216 0,19068795 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,15938216 0,19059317 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,15938216 0,19049849 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,15938216 0,19040391 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,15938216 0,19030941 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,15938216 0,19021501 ! membrane depolarization GO:0051899 39 24 0,000 0,15938216 0,19012071 ! pentose metabolic process GO:0019321 35 24 0,000 0,15938216 0,19002649 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,15938216 0,18993238 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,15938216 0,18983835 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,15938216 0,18974442 GO:0033013|tetrapyrrole metabolic process, ! regulation of multi-organism process GO:0043900 36 24 0,000 0,15938216 0,18965058 ! regulation of amine transport GO:0051952 40 24 0,000 0,15938216 0,18955683 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 1,000 0,15991233 0,19009341 ! Golgi vesicle transport GO:0048193 207 99 1,000 0,15991233 0,18999954 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,16544383 0,19647476 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,16544383 0,19637783 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,16544383 0,196281 ! phototransduction GO:0007602 33 25 0,000 0,16544383 0,19618426 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,16544383 0,19608762 GO:0006479|protein amino acid methylation, ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,16544383 0,19599107 ! chromosome condensation GO:0030261 45 25 0,000 0,16544383 0,19589462 ! osteoblast differentiation GO:0001649 60 25 0,000 0,16544383 0,19579826 ! neural crest cell development GO:0014032 54 25 0,000 0,16544383 0,195702 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,16544383 0,19560583 ! regulation of insulin secretion GO:0050796 37 25 0,000 0,16544383 0,19550976 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,16544383 0,19541378 ! interaction with host GO:0051701 62 25 0,000 0,16544383 0,19531789 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,16544383 0,1952221 ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,16544383 0,1951264 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,16544383 0,1950308 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,16544383 0,19493529 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,16544383 0,19483987 ! telomere organization GO:0032200 43 25 0,000 0,16544383 0,19474455 GO:0000723|telomere maintenance, ! liver development GO:0001889 53 25 0,000 0,16544383 0,19464932 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,171462 0,20163127 ! embryonic pattern specification GO:0009880 44 26 0,000 0,171462 0,20153277 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,171462 0,20143436 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,171462 0,20133605 ! initiation of viral infection GO:0019059 57 26 0,000 0,171462 0,20123784 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,171462 0,20113972 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,171462 0,2010417 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,171462 0,20094378 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,171462 0,20084595 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,171462 0,20074821 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 0,000 0,171462 0,20065057 ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,171462 0,20055303 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,171462 0,20045557 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,171462 0,20035822 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,171462 0,20026096 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,171462 0,20016379 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,171462 0,20006672 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,171462 0,19996974 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,171462 0,19987286 ! blastocyst development GO:0001824 49 26 0,000 0,171462 0,19977606 ! leukocyte proliferation GO:0070661 52 26 0,000 0,171462 0,19967937 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,171462 0,19958276 ! iron ion transport GO:0006826 59 27 0,000 0,17743697 0,20643779 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,17743697 0,20633801 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,17743697 0,20623833 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,17743697 0,20613875 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,17743697 0,20603926 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,17743697 0,20593987 ! autophagy GO:0006914 41 27 0,000 0,17743697 0,20584057 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,17743697 0,20574137 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,17743697 0,20564227 ! glutathione metabolic process GO:0006749 39 27 0,000 0,17743697 0,20554326 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,17743697 0,20544434 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,17743697 0,20534552 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,18336904 0,21210862 ! circadian rhythm GO:0007623 50 28 0,000 0,18336904 0,21200669 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,18336904 0,21190486 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,18336904 0,21180313 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,18336904 0,2117015 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,18336904 0,21159996 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,18336904 0,21149852 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,18336904 0,21139718 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,18336904 0,21129594 ! synaptogenesis GO:0007416 42 28 0,000 0,18336904 0,21119479 ! peptidyl-tyrosine modification GO:0018212 50 28 0,000 0,18336904 0,21109374 ! lipid oxidation GO:0034440 43 28 0,000 0,18336904 0,21099279 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,18336904 0,21089193 ! translational initiation GO:0006413 65 29 0,000 0,18925854 0,21756141 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,18925854 0,21745752 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,18925854 0,21735372 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,18925854 0,21725002 ! complement activation, classical pathway GO:0006958 48 29 0,000 0,18925854 0,21714642 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,18925854 0,21704292 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,18925854 0,21693951 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,18925854 0,21683621 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,18925854 0,216733 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,18925854 0,21662989 ! cell fate determination GO:0001709 60 29 0,000 0,18925854 0,21652688 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,18925854 0,21642397 ! detection of light stimulus GO:0009583 38 29 0,000 0,18925854 0,21632116 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,18925854 0,21621844 ! regulation of coagulation GO:0050818 46 29 0,000 0,18925854 0,21611582 ! zinc ion transport GO:0006829 45 30 0,000 0,19510575 0,22268711 ! membrane docking GO:0022406 61 30 0,000 0,19510575 0,22258152 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,19510575 0,22247603 ! regulation of innate immune response GO:0045088 51 30 0,000 0,19510575 0,22237064 ! acute-phase response GO:0006953 49 30 0,000 0,19510575 0,22226535 ! myofibril assembly GO:0030239 47 30 0,000 0,19510575 0,22216016 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,19510575 0,22205507 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,19510575 0,22195008 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,19510575 0,22184519 ! phospholipid transport GO:0015914 51 30 0,000 0,19510575 0,2217404 ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,19510575 0,22163571 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,19510575 0,22153111 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,19510575 0,22142662 ! response to heat GO:0009408 50 30 0,000 0,19510575 0,22132222 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,20091098 0,2278001 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,20091098 0,2276928 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,20091098 0,2275856 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,20091098 0,2274785 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,20091098 0,2273715 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,20091098 0,22726461 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,20091098 0,22715781 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,20091098 0,22705111 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,20091098 0,22694452 ! ovulation cycle process GO:0022602 49 31 0,000 0,20091098 0,22683802 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,20091098 0,22673162 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,20091098 0,22662533 ! peptide transport GO:0015833 55 31 0,000 0,20091098 0,22651913 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,20091098 0,22641303 ! iron ion homeostasis GO:0055072 54 31 0,000 0,20091098 0,22630703 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,20091098 0,22620113 ! natural killer cell activation GO:0030101 45 31 0,000 0,20091098 0,22609533 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,20091098 0,22598963 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,20091098 0,22588403 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,20091098 0,22577852 ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,20091098 0,22567312 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,20667454 0,2320387 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,20667454 0,23193047 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,20667454 0,23182235 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,20667454 0,23171432 ! cholesterol transport GO:0030301 56 32 0,000 0,20667454 0,2316064 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,20667454 0,23149857 ! spliceosome assembly GO:0000245 67 32 0,000 0,20667454 0,23139085 ! spindle organization GO:0007051 46 32 0,000 0,20667454 0,23128322 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,20667454 0,2311757 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,20667454 0,23106828 ! muscle cell development GO:0055001 49 32 0,000 0,20667454 0,23096095 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,20667454 0,23085373 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,20667454 0,2307466 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,20667454 0,23063958 ! ovulation cycle GO:0042698 51 32 0,000 0,20667454 0,23053265 ! BMP signaling pathway GO:0030509 64 32 0,000 0,20667454 0,23042583 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,20667454 0,2303191 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,20667454 0,23021247 ! positive regulation of catabolic process GO:0009896 64 32 0,000 0,20667454 0,23010594 ! gene silencing GO:0016458 65 32 0,000 0,20667454 0,22999951 ! post-embryonic development GO:0009791 69 33 0,000 0,21239671 0,2362582 ! protein targeting to membrane GO:0006612 68 33 0,000 0,21239671 0,23614902 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,21239671 0,23603995 ! ceramide metabolic process GO:0006672 64 33 0,000 0,21239671 0,23593097 ! sterol transport GO:0015918 57 33 0,000 0,21239671 0,2358221 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,21239671 0,23571332 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,21239671 0,23560465 ! adult locomotory behavior GO:0008344 59 33 0,000 0,21239671 0,23549608 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,2180778 0,24168364 ! glial cell differentiation GO:0010001 63 34 0,000 0,2180778 0,24157237 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,2180778 0,2414612 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,2180778 0,24135013 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,2180778 0,24123917 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,2180778 0,2411283 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,2180778 0,24101754 ! placenta development GO:0001890 53 34 0,000 0,2180778 0,24090688 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 0,000 0,2180778 0,24079632 ! negative regulation of secretion GO:0051048 63 35 0,000 0,2237181 0,24691089 ! odontogenesis GO:0042476 66 35 0,000 0,2237181 0,24679768 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,2237181 0,24668458 ! female gonad development GO:0008585 58 35 0,000 0,2237181 0,24657157 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,2237181 0,24645868 GO:0006639|acylglycerol metabolic process, ! cytokine production GO:0001816 59 35 0,000 0,2237181 0,24634588 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,2293179 0,25239655 ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,2293179 0,25228115 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,2293179 0,25216584 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,2293179 0,25205065 ! positive regulation of cell development GO:0010720 80 36 0,000 0,2293179 0,25193556 ! regulation of proteolysis GO:0030162 72 36 0,000 0,2293179 0,25182057 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,2293179 0,25170569 ! aerobic respiration GO:0009060 55 36 0,000 0,2293179 0,25159091 ! embryonic organ development GO:0048568 57 36 0,000 0,2293179 0,25147624 ! RNA export from nucleus GO:0006405 56 37 0,000 0,23487749 0,25745569 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,23487749 0,25733845 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,23487749 0,25722132 ! sister chromatid segregation GO:0000819 58 37 0,000 0,23487749 0,25710429 ! actomyosin structure organization GO:0031032 62 37 0,000 0,23487749 0,25698738 ! organic anion transport GO:0015711 68 37 0,000 0,23487749 0,25687056 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,23487749 0,25675386 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,23487749 0,25663726 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,23487749 0,25652076 GO:0015986|ATP synthesis coupled proton transport, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,24039716 0,26242993 GO:0006956|complement activation, ! positive regulation of DNA metabolic process GO:0051054 72 38 0,000 0,24039716 0,26231091 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,24039716 0,262192 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,24039716 0,2620732 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,24039716 0,26195451 ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,24039716 0,26183592 GO:0046660|female sex differentiation, ! lipid homeostasis GO:0055088 67 38 0,000 0,24039716 0,26171745 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,24039716 0,26159908 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,24039716 0,26148081 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,24039716 0,26136266 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,24039716 0,26124461 ! mRNA catabolic process GO:0006402 71 39 0,000 0,24587719 0,26707924 ! ear morphogenesis GO:0042471 60 39 0,000 0,24587719 0,26695871 ! organic ether metabolic process GO:0018904 55 39 0,000 0,24587719 0,2668383 ! ion transmembrane transport GO:0034220 66 39 0,000 0,24587719 0,26671799 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,24587719 0,2665978 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,24587719 0,26647771 ! RNA modification GO:0009451 57 39 0,000 0,24587719 0,26635773 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,24587719 0,26623785 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,25131786 0,27200665 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,25131786 0,27188434 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,25131786 0,27176215 ! feeding behavior GO:0007631 59 40 0,000 0,25131786 0,27164006 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,25131786 0,27151808 ! mesenchymal cell development GO:0014031 87 40 0,000 0,25131786 0,27139622 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,25131786 0,27127446 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,25671947 0,27698073 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,25671947 0,27685658 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,25671947 0,27673254 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,25671947 0,27660861 ! gliogenesis GO:0042063 88 41 0,000 0,25671947 0,2764848 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,25671947 0,27636109 ! female gamete generation GO:0007292 61 41 0,000 0,25671947 0,27623749 ! response to reactive oxygen species GO:0000302 67 42 0,000 0,26208228 0,28188196 ! regulation of tube size GO:0035150 71 42 0,000 0,26208228 0,28175601 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,26208228 0,28163017 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,26208228 0,28150444 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,26208228 0,28137883 ! regulation of protein secretion GO:0050708 71 42 0,000 0,26208228 0,28125332 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,26208228 0,28112793 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,26740657 0,28671132 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,26740657 0,28658361 ! glucose transport GO:0015758 65 43 0,000 0,26740657 0,28645601 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,26740657 0,28632853 ! striated muscle contraction GO:0006941 77 43 0,000 0,26740657 0,28620116 ! phagocytosis GO:0006909 90 43 0,000 0,26740657 0,2860739 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,26740657 0,28594676 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,27269262 0,29146977 ! hexose transport GO:0008645 67 44 0,000 0,27269262 0,29134034 GO:0015749|monosaccharide transport, ! biopolymer methylation GO:0043414 84 44 0,000 0,27269262 0,29121103 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,27269262 0,29108183 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,27269262 0,29095275 ! developmental growth GO:0048589 82 44 0,000 0,27269262 0,29082378 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,27794071 0,29628948 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,27794071 0,29615826 ! leukocyte migration GO:0050900 68 45 0,000 0,27794071 0,29602716 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,27794071 0,29589617 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,27794071 0,2957653 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,27794071 0,29563455 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,27794071 0,29550391 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,27794071 0,29537339 ! cell growth GO:0016049 84 45 0,000 0,27794071 0,29524298 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,2831511 0,30064499 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,2831511 0,30051237 ! positive regulation of defense response GO:0031349 76 47 0,000 0,28832406 0,30586759 ! response to calcium ion GO:0051592 81 47 0,000 0,28832406 0,30573279 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,28832406 0,3055981 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,28832406 0,30546354 ! methylation GO:0032259 90 47 0,000 0,28832406 0,30532909 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,29345987 0,31063108 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,29345987 0,31049448 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,29345987 0,310358 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,29855878 0,31561179 ! regulation of ion transport GO:0043269 77 49 0,000 0,29855878 0,31547318 ! response to temperature stimulus GO:0009266 76 49 0,000 0,29855878 0,31533469 ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,29855878 0,31519633 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,29855878 0,31505808 ! neuromuscular process GO:0050905 99 50 0,000 0,30362107 0,32025966 ! regulation of ossification GO:0030278 117 50 0,000 0,30362107 0,32011932 ! inner ear development GO:0048839 79 50 0,000 0,30362107 0,3199791 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,30362107 0,319839 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,30362107 0,31969903 ! viral infectious cycle GO:0019058 99 51 0,000 0,30864698 0,32484892 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,30864698 0,32470688 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,30864698 0,32456497 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,30864698 0,32442317 ! excretion GO:0007588 83 51 0,000 0,30864698 0,3242815 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,30864698 0,32413996 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,30864698 0,32399853 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,30864698 0,32385724 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,31363679 0,32894949 ! membrane fusion GO:0006944 110 52 0,000 0,31363679 0,32880615 ! positive regulation of growth GO:0045927 90 52 0,000 0,31363679 0,32866294 ! amino acid activation GO:0043038 92 52 0,000 0,31363679 0,32851986 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 76 53 0,000 0,31859075 0,33356369 ! RNA catabolic process GO:0006401 93 53 0,000 0,31859075 0,33341859 ! regulation of translational initiation GO:0006446 82 53 0,000 0,31859075 0,33327363 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,31859075 0,33312879 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,31859075 0,33298408 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,31859075 0,33283949 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,32350912 0,33783114 ! cell recognition GO:0008037 85 54 0,000 0,32350912 0,33768457 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,32350912 0,33753814 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,32350912 0,33739183 ! chloride transport GO:0006821 90 55 0,000 0,32839215 0,34233601 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,32839215 0,34218775 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,32839215 0,34203962 ! RNA elongation GO:0006354 79 55 0,000 0,32839215 0,34189161 ! nuclear export GO:0051168 97 55 0,000 0,32839215 0,34174373 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,33324009 0,34663885 ! proton transport GO:0015992 94 56 0,000 0,33324009 0,34648905 ! positive regulation of organelle organization GO:0010638 100 56 0,000 0,33324009 0,34633938 ! hydrogen transport GO:0006818 97 58 0,000 0,34283173 0,35615421 ! positive regulation of secretion GO:0051047 95 59 0,000 0,34757592 0,36092691 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,34757592 0,3607712 GO:0032313|regulation of Rab GTPase activity, ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,35228601 0,36550243 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,35228601 0,36534489 ! regulation of heart contraction GO:0008016 110 60 0,000 0,35228601 0,36518748 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,35228601 0,36503021 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,35696226 0,3697164 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,35696226 0,36955731 ! tRNA processing GO:0008033 89 61 0,000 0,35696226 0,36939836 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,35696226 0,36923955 ! ear development GO:0043583 103 62 0,000 0,3616049 0,37388113 ! viral reproductive process GO:0022415 126 62 0,000 0,3616049 0,37372052 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,3616049 0,37356006 ! regulation of mitosis GO:0007088 105 63 0,000 0,36621417 0,37815935 GO:0051783|regulation of nuclear division, ! detection of external stimulus GO:0009581 91 63 0,000 0,36621417 0,37799712 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,36621417 0,37783503 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,37079032 0,38239242 ! cell redox homeostasis GO:0045454 102 64 0,000 0,37079032 0,38222858 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,37079032 0,38206488 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,37079032 0,38190133 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,37533358 0,38641531 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,37533358 0,38625003 ! myeloid cell differentiation GO:0030099 111 65 0,000 0,37533358 0,3860849 ! extracellular matrix organization GO:0030198 133 66 0,000 0,37984418 0,39055773 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,38432236 0,39499342 ! chromosome segregation GO:0007059 113 67 0,000 0,38432236 0,39482476 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,38432236 0,39465625 ! activation of immune response GO:0002253 105 67 0,000 0,38432236 0,39448788 ! amino acid transport GO:0006865 125 68 0,000 0,38876835 0,3988813 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,38876835 0,39871127 ! viral reproduction GO:0016032 134 68 0,000 0,38876835 0,39854139 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,39318238 0,40289472 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,39318238 0,40272321 ! antigen processing and presentation GO:0019882 104 69 0,000 0,39318238 0,40255183 ! amine catabolic process GO:0009310 117 71 0,000 0,40191548 0,41131802 ! humoral immune response GO:0006959 109 71 0,000 0,40191548 0,41114314 ! regulation of immune effector process GO:0002697 137 71 0,000 0,40191548 0,4109684 ! acute inflammatory response GO:0002526 113 72 0,000 0,40623501 0,41520876 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 0,000 0,40623501 0,41503245 ! carbohydrate transport GO:0008643 110 72 0,000 0,40623501 0,41485629 ! regulation of blood pressure GO:0008217 125 73 0,000 0,41052347 0,4190579 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,41052347 0,41888018 ! fertilization GO:0009566 90 73 0,000 0,41052347 0,41870262 ! transition metal ion transport GO:0000041 126 74 0,000 0,41478111 0,42286582 ! neurotransmitter transport GO:0006836 123 74 0,000 0,41478111 0,42268672 ! exocytosis GO:0006887 133 74 0,000 0,41478111 0,42250777 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,41900813 0,42663291 ! rhythmic process GO:0048511 128 75 0,000 0,41900813 0,42645244 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,42320477 0,43054151 ! defense response to bacterium GO:0042742 89 76 0,000 0,42320477 0,43035954 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,42320477 0,43017772 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,43150772 0,43843226 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,43561448 0,44241808 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,43561448 0,44223141 ! response to metal ion GO:0010038 140 80 0,000 0,4396917 0,4461823 ! muscle cell differentiation GO:0042692 159 80 0,000 0,4396917 0,4459942 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,4396917 0,44580625 ! inorganic anion transport GO:0015698 138 80 0,000 0,4396917 0,44561847 ! digestion GO:0007586 112 81 0,000 0,44373961 0,44953158 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,44373961 0,44934238 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,4477584 0,45322117 ! response to nutrient GO:0007584 125 82 0,000 0,4477584 0,45303058 ! response to unfolded protein GO:0006986 131 85 0,000 0,4596422 0,46485882 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,4596422 0,4646635 ! amine biosynthetic process GO:0009309 138 86 0,000 0,46354662 0,46841377 ! response to inorganic substance GO:0010035 153 86 0,000 0,46354662 0,46821712 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,46354662 0,46802064 ! amine transport GO:0015837 155 86 0,000 0,46354662 0,46782432 ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,46742296 0,47153864 ! cellular respiration GO:0045333 135 88 0,000 0,47127142 0,47522173 ! positive regulation of protein modification process GO:0031401 136 88 0,000 0,47127142 0,47502264 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,47127142 0,47482372 ! cellular defense response GO:0006968 114 89 0,000 0,4750922 0,47847293 ! sterol metabolic process GO:0016125 152 91 0,000 0,4826515 0,48588264 ! response to protein stimulus GO:0051789 149 91 0,000 0,4826515 0,48567942 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,4826515 0,48547638 ! regulation of defense response GO:0031347 149 92 0,000 0,48639041 0,48903273 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,48639041 0,48882846 ! vitamin metabolic process GO:0006766 139 92 0,000 0,48639041 0,48862436 ! female pregnancy GO:0007565 164 94 0,000 0,49378774 0,49584862 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,49744654 0,49931429 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,50107901 0,50275066 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,50107901 0,5025411 ! positive regulation of immune response GO:0050778 156 96 0,000 0,50107901 0,50233171 ! detection of stimulus GO:0051606 151 96 0,000 0,50107901 0,50212249 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,50468535 0,50552579 ! protein ubiquitination GO:0016567 217 97 0,000 0,50468535 0,50531541 ! response to virus GO:0009615 160 98 0,000 0,50826573 0,50868858 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,50826573 0,50847707 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,50826573 0,50826573 GO:0016054|organic acid catabolic process,