pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6808-VanDeVijver-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/vantveer-oligo_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of cell migration GO:0030334 71 71 6,000 2,775E-09 5,114E-06 ! regulation of locomotion GO:0040012 79 79 6,000 5,944E-09 5,477E-06 ! regulation of cell motion GO:0051270 79 79 6,000 5,944E-09 3,652E-06 ! positive regulation of cell migration GO:0030335 36 36 4,000 1,163E-07 5,358E-05 ! positive regulation of cell motion GO:0051272 39 39 4,000 1,764E-07 6,502E-05 ! regulation of anatomical structure morphogenesis GO:0022603 90 86 5,000 3,595E-07 1,104E-04 ! positive regulation of glucose metabolic process GO:0010907 5 5 2,000 3,714E-07 9,777E-05 ! regulation of cellular carbohydrate catabolic process GO:0043471 6 6 2,000 7,41E-07 1,707E-04 GO:0043470|regulation of carbohydrate catabolic process, GO:0006110|regulation of glycolysis, ! positive regulation of cellular catabolic process GO:0031331 7 7 2,000 1,294E-06 2,649E-04 ! positive regulation of carbohydrate metabolic process GO:0045913 7 7 2,000 1,294E-06 2,384E-04 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of generation of precursor metabolites and energy GO:0043467 8 8 2,000 2,065E-06 3,46E-04 ! protein amino acid autophosphorylation GO:0046777 28 28 3,000 2,206E-06 3,388E-04 ! regulation of nitric-oxide synthase activity GO:0050999 9 9 2,000 3,091E-06 4,382E-04 ! gamma-aminobutyric acid signaling pathway GO:0007214 9 9 2,000 3,091E-06 4,069E-04 ! positive regulation of endothelial cell proliferation GO:0001938 9 9 2,000 3,091E-06 3,798E-04 ! regulation of glucose metabolic process GO:0010906 10 10 2,000 4,406E-06 5,075E-04 ! regulation of angiogenesis GO:0045765 35 34 3,000 4,926E-06 5,341E-04 ! positive regulation of nitric oxide biosynthetic process GO:0045429 11 11 2,000 6,044E-06 6,188E-04 ! regulation of monooxygenase activity GO:0032768 11 11 2,000 6,044E-06 5,862E-04 ! regulation of cellular carbohydrate metabolic process GO:0010675 11 11 2,000 6,044E-06 5,569E-04 GO:0006109|regulation of carbohydrate metabolic process, ! cell-matrix adhesion GO:0007160 39 38 3,000 7,769E-06 6,818E-04 ! vasculogenesis GO:0001570 13 13 2,000 1,043E-05 8,736E-04 ! regulation of nitric oxide biosynthetic process GO:0045428 13 13 2,000 1,043E-05 8,356E-04 ! positive regulation of transferase activity GO:0051347 91 88 4,000 1,072E-05 8,229E-04 GO:0033674|positive regulation of kinase activity, ! cell-substrate adhesion GO:0031589 43 42 3,000 1,167E-05 8,603E-04 ! response to retinoic acid GO:0032526 14 14 2,000 1,324E-05 9,386E-04 GO:0033189|response to vitamin A, ! response to vitamin GO:0033273 15 15 2,000 1,651E-05 1,127E-03 ! insulin receptor signaling pathway GO:0008286 17 15 2,000 1,651E-05 1,087E-03 ! cellular response to hormone stimulus GO:0032870 48 46 3,000 1,686E-05 1,071E-03 ! negative regulation of adenylate cyclase activity GO:0007194 16 16 2,000 2,028E-05 1,246E-03 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of catabolic process GO:0009896 16 16 2,000 2,028E-05 1,206E-03 ! ossification GO:0001503 50 49 3,000 2,173E-05 1,252E-03 GO:0060348|bone development, ! positive regulation of MAP kinase activity GO:0043406 50 49 3,000 2,173E-05 1,214E-03 ! response to nutrient GO:0007584 49 49 3,000 2,173E-05 1,178E-03 ! cell junction assembly GO:0034329 18 17 2,000 2,457E-05 1,294E-03 ! tissue remodeling GO:0048771 17 17 2,000 2,457E-05 1,258E-03 ! regulation of oxidoreductase activity GO:0051341 17 17 2,000 2,457E-05 1,224E-03 ! regulation of cellular catabolic process GO:0031329 18 18 2,000 2,941E-05 1,427E-03 ! epidermal growth factor receptor signaling pathway GO:0007173 18 18 2,000 2,941E-05 1,39E-03 ! response to hypoxia GO:0001666 53 53 3,000 2,976E-05 1,371E-03 ! response to oxygen levels GO:0070482 55 54 3,000 3,206E-05 1,441E-03 ! regulation of endothelial cell proliferation GO:0001936 19 19 2,000 3,485E-05 1,529E-03 ! multicellular organismal metabolic process GO:0044236 19 19 2,000 3,485E-05 1,494E-03 ! peptidyl-tyrosine phosphorylation GO:0018108 20 19 2,000 3,485E-05 1,46E-03 ! regulation of cell shape GO:0008360 21 19 2,000 3,485E-05 1,427E-03 ! peptidyl-tyrosine modification GO:0018212 21 20 2,000 4,09E-05 1,639E-03 ! peptidyl-amino acid modification GO:0018193 61 59 3,000 4,561E-05 1,788E-03 ! cellular response to insulin stimulus GO:0032869 23 21 2,000 4,761E-05 1,828E-03 ! cell junction organization GO:0034330 23 22 2,000 5,5E-05 2,069E-03 ! cytokinesis GO:0000910 23 22 2,000 5,5E-05 2,027E-03 ! positive regulation of growth GO:0045927 23 23 2,000 6,311E-05 2,281E-03 ! regulation of MAP kinase activity GO:0043405 67 66 3,000 7,106E-05 2,518E-03 ! glucose homeostasis GO:0042593 24 24 2,000 7,196E-05 2,502E-03 GO:0033500|carbohydrate homeostasis, ! regulation of gene-specific transcription GO:0032583 25 25 2,000 8,159E-05 2,784E-03 ! heart morphogenesis GO:0003007 25 25 2,000 8,159E-05 2,734E-03 ! response to nutrient levels GO:0031667 69 69 3,000 8,464E-05 2,785E-03 ! response to insulin stimulus GO:0032868 28 26 2,000 9,202E-05 2,975E-03 ! response to extracellular stimulus GO:0009991 72 72 3,000 1E-04 3,178E-03 ! cartilage development GO:0051216 29 28 2,000 1,154E-04 3,605E-03 ! hemoglobin biosynthetic process GO:0042541 5 5 1,000 1,159E-04 3,56E-03 ! filopodium assembly GO:0046847 7 5 1,000 1,159E-04 3,501E-03 GO:0030035|microspike assembly, ! mRNA stabilization GO:0048255 5 5 1,000 1,159E-04 3,445E-03 GO:0043489|RNA stabilization, ! 2-oxoglutarate metabolic process GO:0006103 5 5 1,000 1,159E-04 3,39E-03 ! heart looping GO:0001947 5 5 1,000 1,159E-04 3,337E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 5 5 1,000 1,159E-04 3,286E-03 ! regulation of phospholipase A2 activity GO:0032429 5 5 1,000 1,159E-04 3,236E-03 ! regulation of vascular endothelial growth factor production GO:0010574 5 5 1,000 1,159E-04 3,188E-03 ! protein heterooligomerization GO:0051291 5 5 1,000 1,159E-04 3,141E-03 ! positive regulation of monooxygenase activity GO:0032770 5 5 1,000 1,159E-04 3,095E-03 ! regulation of hormone metabolic process GO:0032350 5 5 1,000 1,159E-04 3,051E-03 ! peptidyl-lysine modification GO:0018205 5 5 1,000 1,159E-04 3,008E-03 ! positive regulation of erythrocyte differentiation GO:0045648 5 5 1,000 1,159E-04 2,966E-03 ! positive regulation of blood vessel endothelial cell migration GO:0043536 5 5 1,000 1,159E-04 2,926E-03 ! nucleus localization GO:0051647 5 5 1,000 1,159E-04 2,886E-03 ! positive regulation of cell cycle GO:0045787 29 29 2,000 1,284E-04 3,156E-03 ! establishment of organelle localization GO:0051656 31 30 2,000 1,424E-04 3,453E-03 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 32 32 2,000 1,731E-04 4,144E-03 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 6 6 1,000 1,735E-04 4,099E-03 ! N-terminal protein amino acid modification GO:0031365 6 6 1,000 1,735E-04 4,047E-03 GO:0018409|peptide or protein amino-terminal blocking, ! virus-host interaction GO:0019048 6 6 1,000 1,735E-04 3,996E-03 ! regulation of lipid kinase activity GO:0043550 6 6 1,000 1,735E-04 3,947E-03 ! cartilage condensation GO:0001502 7 6 1,000 1,735E-04 3,899E-03 ! regulation of positive chemotaxis GO:0050926 6 6 1,000 1,735E-04 3,852E-03 GO:0050927|positive regulation of positive chemotaxis, ! succinate metabolic process GO:0006105 7 6 1,000 1,735E-04 3,806E-03 ! focal adhesion formation GO:0048041 7 6 1,000 1,735E-04 3,761E-03 ! regulation of vascular permeability GO:0043114 6 6 1,000 1,735E-04 3,717E-03 ! regulation of bone resorption GO:0045124 6 6 1,000 1,735E-04 3,675E-03 ! regulation of embryonic development GO:0045995 6 6 1,000 1,735E-04 3,633E-03 ! localization within membrane GO:0051668 6 6 1,000 1,735E-04 3,592E-03 ! blood vessel morphogenesis GO:0048514 84 83 3,000 1,741E-04 3,566E-03 ! regulation of protein complex assembly GO:0043254 33 33 2,000 1,9E-04 3,848E-03 ! positive regulation of protein kinase activity GO:0045860 89 86 3,000 1,998E-04 4,003E-03 ! response to peptide hormone stimulus GO:0043434 36 34 2,000 2,079E-04 4,121E-03 ! heart development GO:0007507 90 87 3,000 2,09E-04 4,097E-03 ! regulation of cell morphogenesis GO:0022604 38 35 2,000 2,269E-04 4,402E-03 ! positive regulation of phosphorylation GO:0042327 35 35 2,000 2,269E-04 4,356E-03 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 7 7 1,000 2,423E-04 4,604E-03 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 7 7 1,000 2,423E-04 4,557E-03 ! regulation of chemokine production GO:0032642 7 7 1,000 2,423E-04 4,511E-03 ! oxaloacetate metabolic process GO:0006107 7 7 1,000 2,423E-04 4,466E-03 ! hemoglobin metabolic process GO:0020027 7 7 1,000 2,423E-04 4,422E-03 ! negative regulation of cell-substrate adhesion GO:0010812 8 7 1,000 2,423E-04 4,379E-03 GO:0001953|negative regulation of cell-matrix adhesion, ! regulation of mRNA stability GO:0043488 7 7 1,000 2,423E-04 4,336E-03 ! positive regulation of phosphorus metabolic process GO:0010562 36 36 2,000 2,47E-04 4,377E-03 GO:0045937|positive regulation of phosphate metabolic process, ! regulation of adenylate cyclase activity GO:0045761 37 37 2,000 2,681E-04 4,707E-03 GO:0031279|regulation of cyclase activity, GO:0051339|regulation of lyase activity, ! lung development GO:0030324 38 37 2,000 2,681E-04 4,662E-03 ! blood vessel development GO:0001568 95 94 3,000 2,816E-04 4,851E-03 ! regulation of homeostatic process GO:0032844 38 38 2,000 2,905E-04 4,957E-03 ! vasculature development GO:0001944 97 96 3,000 3,054E-04 5,163E-03 ! regulation of cAMP biosynthetic process GO:0030817 39 39 2,000 3,14E-04 5,26E-03 ! activation of MAPK activity GO:0000187 39 39 2,000 3,14E-04 5,213E-03 ! respiratory tube development GO:0030323 40 39 2,000 3,14E-04 5,166E-03 ! respiratory system development GO:0060541 40 39 2,000 3,14E-04 5,12E-03 ! negative regulation of bone remodeling GO:0046851 8 8 1,000 3,224E-04 5,212E-03 ! phosphagen metabolic process GO:0006599 8 8 1,000 3,224E-04 5,167E-03 GO:0006600|creatine metabolic process, ! cell-cell junction assembly GO:0007043 8 8 1,000 3,224E-04 5,123E-03 ! positive regulation of endothelial cell migration GO:0010595 8 8 1,000 3,224E-04 5,079E-03 ! sex determination GO:0007530 8 8 1,000 3,224E-04 5,036E-03 ! plasma membrane fusion GO:0045026 8 8 1,000 3,224E-04 4,993E-03 ! positive regulation of leukocyte migration GO:0002687 8 8 1,000 3,224E-04 4,952E-03 ! branched chain family amino acid metabolic process GO:0009081 8 8 1,000 3,224E-04 4,911E-03 ! regulation of RNA stability GO:0043487 8 8 1,000 3,224E-04 4,871E-03 ! regulation of cAMP metabolic process GO:0030814 40 40 2,000 3,386E-04 5,074E-03 ! organelle localization GO:0051640 41 40 2,000 3,386E-04 5,033E-03 ! response to hormone stimulus GO:0009725 102 100 3,000 3,571E-04 5,265E-03 ! regulation of nucleotide biosynthetic process GO:0030808 41 41 2,000 3,645E-04 5,332E-03 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! regulation of cyclic nucleotide metabolic process GO:0030799 42 42 2,000 3,917E-04 5,684E-03 ! positive regulation of cell projection organization GO:0031346 9 9 1,000 4,137E-04 5,956E-03 ! negative regulation of cell cycle process GO:0010948 9 9 1,000 4,137E-04 5,91E-03 ! platelet-derived growth factor receptor signaling pathway GO:0048008 9 9 1,000 4,137E-04 5,864E-03 ! histone acetylation GO:0016573 9 9 1,000 4,137E-04 5,82E-03 ! positive regulation of oxidoreductase activity GO:0051353 9 9 1,000 4,137E-04 5,776E-03 ! negative regulation of tissue remodeling GO:0034104 9 9 1,000 4,137E-04 5,732E-03 ! regulation of leukocyte migration GO:0002685 9 9 1,000 4,137E-04 5,689E-03 ! regulation of blood vessel endothelial cell migration GO:0043535 9 9 1,000 4,137E-04 5,647E-03 ! regulation of nucleotide metabolic process GO:0006140 43 43 2,000 4,201E-04 5,693E-03 ! positive regulation of anti-apoptosis GO:0045768 10 10 1,000 5,16E-04 6,941E-03 GO:0045767|regulation of anti-apoptosis, ! calcium-independent cell-cell adhesion GO:0016338 10 10 1,000 5,16E-04 6,891E-03 ! cell-substrate junction assembly GO:0007044 11 10 1,000 5,16E-04 6,841E-03 ! regulation of erythrocyte differentiation GO:0045646 10 10 1,000 5,16E-04 6,792E-03 ! epithelial to mesenchymal transition GO:0001837 10 10 1,000 5,16E-04 6,744E-03 ! negative regulation of homeostatic process GO:0032845 10 10 1,000 5,16E-04 6,697E-03 ! regulation of catabolic process GO:0009894 48 47 2,000 5,469E-04 7,049E-03 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 11 11 1,000 6,293E-04 8,054E-03 ! myeloid leukocyte differentiation GO:0002573 12 11 1,000 6,293E-04 7,998E-03 ! protein amino acid acetylation GO:0006473 11 11 1,000 6,293E-04 7,944E-03 ! interaction with host GO:0051701 11 11 1,000 6,293E-04 7,89E-03 ! negative regulation of angiogenesis GO:0016525 11 11 1,000 6,293E-04 7,836E-03 ! muscle maintenance GO:0046716 12 11 1,000 6,293E-04 7,784E-03 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 12 12 1,000 7,535E-04 9,258E-03 ! positive regulation of angiogenesis GO:0045766 12 12 1,000 7,535E-04 9,197E-03 ! collagen metabolic process GO:0032963 12 12 1,000 7,535E-04 9,137E-03 ! osteoblast differentiation GO:0001649 12 12 1,000 7,535E-04 9,077E-03 ! fibroblast growth factor receptor signaling pathway GO:0008543 12 12 1,000 7,535E-04 9,018E-03 ! regulation of chromosome organization GO:0033044 12 12 1,000 7,535E-04 8,96E-03 ! positive regulation of multicellular organism growth GO:0040018 12 12 1,000 7,535E-04 8,902E-03 ! somitogenesis GO:0001756 13 12 1,000 7,535E-04 8,846E-03 ! regulation of mitotic metaphase/anaphase transition GO:0030071 13 12 1,000 7,535E-04 8,79E-03 ! positive regulation of DNA replication GO:0045740 14 13 1,000 8,886E-04 0,0103005 ! positive regulation of smooth muscle cell proliferation GO:0048661 13 13 1,000 8,886E-04 0,01023612 ! positive regulation of JAK-STAT cascade GO:0046427 13 13 1,000 8,886E-04 0,01017255 ! multicellular organismal macromolecule metabolic process GO:0044259 13 13 1,000 8,886E-04 0,01010975 ! actin filament bundle formation GO:0051017 13 13 1,000 8,886E-04 0,01004773 ! regulation of endothelial cell migration GO:0010594 13 13 1,000 8,886E-04 9,986E-03 ! coenzyme catabolic process GO:0009109 13 13 1,000 8,886E-04 9,926E-03 GO:0046356|acetyl-CoA catabolic process, GO:0006099|tricarboxylic acid cycle, ! positive regulation of locomotion GO:0040017 13 13 1,000 8,886E-04 9,866E-03 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, GO:0050920|regulation of chemotaxis, ! neural crest cell migration GO:0001755 14 13 1,000 8,886E-04 9,807E-03 ! cell-cell junction organization GO:0045216 13 13 1,000 8,886E-04 9,749E-03 ! regulation of cell-substrate adhesion GO:0010810 14 13 1,000 8,886E-04 9,691E-03 GO:0001952|regulation of cell-matrix adhesion, ! protein tetramerization GO:0051262 13 13 1,000 8,886E-04 9,634E-03 ! acetyl-CoA metabolic process GO:0006084 14 14 1,000 1,035E-03 0,01115015 ! cellular iron ion homeostasis GO:0006879 14 14 1,000 1,035E-03 0,01108532 ! protein amino acid acylation GO:0043543 14 14 1,000 1,035E-03 0,01102125 ! calcium-dependent cell-cell adhesion GO:0016339 14 14 1,000 1,035E-03 0,01095791 ! positive regulation of epithelial cell proliferation GO:0050679 14 14 1,000 1,035E-03 0,01089529 ! regulation of behavior GO:0050795 14 14 1,000 1,035E-03 0,01083338 ! regulation of protein amino acid phosphorylation GO:0001932 62 61 2,000 1,176E-03 0,01224135 ! negative regulation of protein complex assembly GO:0031333 15 15 1,000 1,191E-03 0,0123333 ! positive regulation of myeloid cell differentiation GO:0045639 16 15 1,000 1,191E-03 0,0122644 ! regulation of cellular component biogenesis GO:0044087 63 62 2,000 1,233E-03 0,0126205 ! negative regulation of cellular component organization GO:0051129 65 63 2,000 1,291E-03 0,0131482 ! angiogenesis GO:0001525 65 64 2,000 1,352E-03 0,01368769 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 16 16 1,000 1,358E-03 0,01368091 ! positive regulation of mitosis GO:0045840 16 16 1,000 1,358E-03 0,01360656 GO:0051785|positive regulation of nuclear division, ! segmentation GO:0035282 17 16 1,000 1,358E-03 0,01353301 ! iron ion homeostasis GO:0055072 16 16 1,000 1,358E-03 0,01346026 ! cofactor catabolic process GO:0051187 16 16 1,000 1,358E-03 0,01338828 ! positive regulation of cellular component organization GO:0051130 65 65 2,000 1,414E-03 0,01386029 ! regulation of smooth muscle cell proliferation GO:0048660 17 17 1,000 1,536E-03 0,01498087 ! dicarboxylic acid metabolic process GO:0043648 18 17 1,000 1,536E-03 0,01490203 ! glucose transport GO:0015758 17 17 1,000 1,536E-03 0,014824 ! neural crest cell development GO:0014032 19 17 1,000 1,536E-03 0,0147468 GO:0014033|neural crest cell differentiation, ! embryonic organ development GO:0048568 17 17 1,000 1,536E-03 0,01467039 ! regulation of mitotic cell cycle GO:0007346 72 69 2,000 1,68E-03 0,01596447 ! regulation of cell projection organization GO:0031344 19 18 1,000 1,725E-03 0,01630016 ! meiosis I GO:0007127 18 18 1,000 1,725E-03 0,016217 ! hexose transport GO:0008645 18 18 1,000 1,725E-03 0,01613468 GO:0015749|monosaccharide transport, ! symbiosis, encompassing mutualism through parasitism GO:0044403 18 18 1,000 1,725E-03 0,01605319 ! DNA damage checkpoint GO:0000077 19 19 1,000 1,923E-03 0,01781367 ! regulation of JAK-STAT cascade GO:0046425 19 19 1,000 1,923E-03 0,0177246 ! cellular response to oxidative stress GO:0034599 19 19 1,000 1,923E-03 0,01763642 ! placenta development GO:0001890 19 19 1,000 1,923E-03 0,01754911 ! negative regulation of cell adhesion GO:0007162 21 20 1,000 2,133E-03 0,0193617 ! establishment or maintenance of cell polarity GO:0007163 21 20 1,000 2,133E-03 0,01926679 ! positive regulation of gene-specific transcription GO:0043193 20 20 1,000 2,133E-03 0,0191728 ! negative regulation of neuron apoptosis GO:0043524 21 20 1,000 2,133E-03 0,01907973 ! positive regulation of multicellular organismal process GO:0051240 76 76 2,000 2,219E-03 0,01975647 ! mitotic sister chromatid segregation GO:0000070 21 21 1,000 2,352E-03 0,02084095 ! G1/S transition of mitotic cell cycle GO:0000082 21 21 1,000 2,352E-03 0,02074123 ! DNA integrity checkpoint GO:0031570 21 21 1,000 2,352E-03 0,02064246 ! regulation of multicellular organism growth GO:0040014 21 21 1,000 2,352E-03 0,02054463 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 21 21 1,000 2,352E-03 0,02044772 ! regulation of protein modification process GO:0031399 79 78 2,000 2,39E-03 0,02068269 ! positive regulation of transcription factor activity GO:0051091 22 22 1,000 2,582E-03 0,02223491 GO:0090047|positive regulation of transcription regulator activity, ! positive regulation of DNA metabolic process GO:0051054 23 22 1,000 2,582E-03 0,02213149 ! sister chromatid segregation GO:0000819 22 22 1,000 2,582E-03 0,02202903 ! cellular amide metabolic process GO:0043603 22 22 1,000 2,582E-03 0,02192752 ! spindle organization GO:0007051 22 22 1,000 2,582E-03 0,02182693 ! neuron migration GO:0001764 22 22 1,000 2,582E-03 0,02172727 ! aerobic respiration GO:0009060 22 22 1,000 2,582E-03 0,02162851 ! MAPKKK cascade GO:0000165 82 81 2,000 2,662E-03 0,02220341 ! tube development GO:0035295 83 81 2,000 2,662E-03 0,02210339 ! mitotic cell cycle checkpoint GO:0007093 24 23 1,000 2,822E-03 0,02332001 ! calcium-mediated signaling GO:0019722 23 23 1,000 2,822E-03 0,0232159 ! cell projection assembly GO:0030031 25 23 1,000 2,822E-03 0,02311272 ! regulation of actin filament polymerization GO:0030833 25 25 1,000 3,332E-03 0,02716928 ! positive regulation of DNA binding GO:0043388 26 25 1,000 3,332E-03 0,02704959 ! JAK-STAT cascade GO:0007259 26 25 1,000 3,332E-03 0,02693096 ! positive regulation of cytokine production GO:0001819 25 25 1,000 3,332E-03 0,02681335 ! positive regulation of binding GO:0051099 27 26 1,000 3,602E-03 0,02886006 ! glycolysis GO:0006096 26 26 1,000 3,602E-03 0,02873512 ! negative regulation of cell migration GO:0030336 26 26 1,000 3,602E-03 0,02861127 ! mesenchymal cell development GO:0014031 29 27 1,000 3,882E-03 0,03070219 GO:0060485|mesenchyme development, GO:0048762|mesenchymal cell differentiation, ! carbohydrate transport GO:0008643 28 28 1,000 4,171E-03 0,03285268 ! histone modification GO:0016570 28 28 1,000 4,171E-03 0,03271288 ! regulation of cell growth GO:0001558 97 96 2,000 4,308E-03 0,03364637 ! viral reproductive process GO:0022415 29 29 1,000 4,471E-03 0,03476557 ! regulation of epithelial cell proliferation GO:0050678 29 29 1,000 4,471E-03 0,0346195 ! covalent chromatin modification GO:0016569 29 29 1,000 4,471E-03 0,03447464 ! regulation of protein polymerization GO:0032271 29 29 1,000 4,471E-03 0,034331 ! response to UV GO:0009411 29 29 1,000 4,471E-03 0,03418855 ! activation of phospholipase C activity GO:0007202 30 30 1,000 4,78E-03 0,03640177 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of response to external stimulus GO:0032103 30 30 1,000 4,78E-03 0,03625197 ! positive regulation of protein amino acid phosphorylation GO:0001934 30 30 1,000 4,78E-03 0,0361034 ! skeletal system morphogenesis GO:0048705 31 30 1,000 4,78E-03 0,03595604 ! vascular process in circulatory system GO:0003018 31 30 1,000 4,78E-03 0,03580987 ! hemopoiesis GO:0030097 104 100 2,000 4,832E-03 0,03605164 ! membrane fusion GO:0006944 31 31 1,000 5,099E-03 0,03789021 ! positive regulation of phospholipase activity GO:0010518 31 31 1,000 5,099E-03 0,03773804 ! regulation of DNA replication GO:0006275 32 31 1,000 5,099E-03 0,03758709 ! regulation of myeloid cell differentiation GO:0045637 32 31 1,000 5,099E-03 0,03743734 ! negative regulation of cell motion GO:0051271 31 31 1,000 5,099E-03 0,03728878 ! glucose catabolic process GO:0006007 32 32 1,000 5,427E-03 0,0395334 ! regulation of phospholipase activity GO:0010517 32 32 1,000 5,427E-03 0,03937776 ! positive regulation of lipase activity GO:0060193 32 32 1,000 5,427E-03 0,03922333 ! activation of protein kinase activity GO:0032147 35 33 1,000 5,765E-03 0,04150251 ! regulation of actin polymerization or depolymerization GO:0008064 33 33 1,000 5,765E-03 0,04134102 ! regulation of neuron apoptosis GO:0043523 34 33 1,000 5,765E-03 0,04118079 ! regulation of actin filament length GO:0030832 34 34 1,000 6,112E-03 0,04349317 ! regulation of bone remodeling GO:0046850 34 34 1,000 6,112E-03 0,04332589 ! regulation of lipid metabolic process GO:0019216 34 34 1,000 6,112E-03 0,04315989 ! viral reproduction GO:0016032 34 34 1,000 6,112E-03 0,04299516 ! regulation of cyclin-dependent protein kinase activity GO:0000079 35 35 1,000 6,469E-03 0,04533117 ! regulation of cellular component size GO:0032535 35 35 1,000 6,469E-03 0,04515946 ! mesoderm development GO:0007498 35 35 1,000 6,469E-03 0,04498905 ! regulation of tissue remodeling GO:0034103 35 35 1,000 6,469E-03 0,04481992 ! regulation of mitosis GO:0007088 37 36 1,000 6,835E-03 0,04717836 GO:0051783|regulation of nuclear division, ! positive regulation of organelle organization GO:0010638 36 36 1,000 6,835E-03 0,04700232 ! integrin-mediated signaling pathway GO:0007229 36 36 1,000 6,835E-03 0,0468276 ! regulation of lipase activity GO:0060191 36 36 1,000 6,835E-03 0,04665416 ! regulation of transcription factor activity GO:0051090 38 37 1,000 7,21E-03 0,04903391 GO:0090046|regulation of transcription regulator activity, ! meiosis GO:0007126 37 37 1,000 7,21E-03 0,04885364 GO:0051327|M phase of meiotic cell cycle, ! negative regulation of protein kinase activity GO:0006469 37 37 1,000 7,21E-03 0,04867469 ! negative regulation of growth GO:0045926 37 37 1,000 7,21E-03 0,04849705 ! DNA damage response, signal transduction GO:0042770 37 37 1,000 7,21E-03 0,04832069 ! regulation of Rho protein signal transduction GO:0035023 37 37 1,000 7,21E-03 0,04814562 ! adaptive immune response GO:0002250 37 37 1,000 7,21E-03 0,04797181 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! negative regulation of kinase activity GO:0033673 38 38 1,000 7,595E-03 0,05034778 ! chromosome segregation GO:0007059 38 38 1,000 7,595E-03 0,05016732 ! hexose catabolic process GO:0019320 38 38 1,000 7,595E-03 0,04998815 ! meiotic cell cycle GO:0051321 38 38 1,000 7,595E-03 0,04981026 ! positive regulation of protein modification process GO:0031401 39 39 1,000 7,988E-03 0,05220562 ! protein oligomerization GO:0051259 39 39 1,000 7,988E-03 0,05202115 ! negative regulation of transferase activity GO:0051348 40 40 1,000 8,391E-03 0,05445063 ! myeloid cell differentiation GO:0030099 42 40 1,000 8,391E-03 0,05425957 ! cell cycle checkpoint GO:0000075 42 41 1,000 8,802E-03 0,0567222 ! monosaccharide catabolic process GO:0046365 41 41 1,000 8,802E-03 0,05652457 ! forebrain development GO:0030900 43 42 1,000 9,223E-03 0,05901939 ! alcohol catabolic process GO:0046164 43 43 1,000 9,652E-03 0,06155353 ! negative regulation of organelle organization GO:0010639 45 44 1,000 0,01009039 0,06412617 ! homophilic cell adhesion GO:0007156 45 45 1,000 0,01053735 0,06673653 ! regulation of actin cytoskeleton organization GO:0032956 46 45 1,000 0,01053735 0,06650798 ! regulation of DNA binding GO:0051101 47 45 1,000 0,01053735 0,06628099 ! regulation of actin filament-based process GO:0032970 47 46 1,000 0,01099299 0,06891184 ! actin filament organization GO:0007015 50 48 1,000 0,0119301 0,07453277 ! regulation of cell cycle process GO:0010564 50 48 1,000 0,0119301 0,07428097 ! leukocyte differentiation GO:0002521 50 49 1,000 0,01241144 0,07701777 ! skeletal muscle tissue development GO:0007519 50 49 1,000 0,01241144 0,07675932 GO:0060538|skeletal muscle organ development, ! regulation of DNA metabolic process GO:0051052 51 50 1,000 0,01290122 0,07952158 ! anatomical structure homeostasis GO:0060249 51 50 1,000 0,01290122 0,07925651 ! anterior/posterior pattern formation GO:0009952 51 50 1,000 0,01290122 0,0789932 ! interphase of mitotic cell cycle GO:0051329 52 51 1,000 0,01339939 0,0817718 GO:0051325|interphase, ! response to light stimulus GO:0009416 53 52 1,000 0,01390589 0,08458271 ! carbohydrate catabolic process GO:0016052 53 53 1,000 0,01442066 0,08742524 ! sulfur metabolic process GO:0006790 55 54 1,000 0,01494363 0,09029874 ! negative regulation of multicellular organismal process GO:0051241 55 54 1,000 0,01494363 0,09000364 ! microtubule cytoskeleton organization GO:0000226 55 55 1,000 0,01547476 0,09289895 ! in utero embryonic development GO:0001701 55 55 1,000 0,01547476 0,09259733 ! regulation of cell adhesion GO:0030155 56 55 1,000 0,01547476 0,09229766 ! reproductive developmental process GO:0003006 56 56 1,000 0,01601397 0,09520565 ! regulation of binding GO:0051098 60 57 1,000 0,01656122 0,09814256 ! rRNA transcription GO:0009303 5 5 0,000 0,0173256 0,1023432 ! positive regulation of protein ubiquitination GO:0031398 5 5 0,000 0,0173256 0,10201623 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 5 5 0,000 0,0173256 0,10169133 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 5 5 0,000 0,0173256 0,1013685 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! neuron fate specification GO:0048665 5 5 0,000 0,0173256 0,10104772 ! reproductive cellular process GO:0048610 5 5 0,000 0,0173256 0,10072896 ! negative regulation of blood pressure GO:0045776 6 5 0,000 0,0173256 0,1004122 ! prostate gland development GO:0030850 5 5 0,000 0,0173256 0,10009743 ! metencephalon development GO:0022037 5 5 0,000 0,0173256 0,09978462 ! water transport GO:0006833 5 5 0,000 0,0173256 0,09947377 GO:0042044|fluid transport, ! forebrain regionalization GO:0021871 5 5 0,000 0,0173256 0,09916484 ! DNA synthesis during DNA repair GO:0000731 5 5 0,000 0,0173256 0,09885783 ! positive regulation of B cell proliferation GO:0030890 5 5 0,000 0,0173256 0,09855271 ! glycerol metabolic process GO:0006071 5 5 0,000 0,0173256 0,09824947 ! regulation of cellular amine metabolic process GO:0033238 5 5 0,000 0,0173256 0,09794809 GO:0042053|regulation of dopamine metabolic process, GO:0042069|regulation of catecholamine metabolic process, ! meiotic prophase I GO:0007128 5 5 0,000 0,0173256 0,09764856 GO:0051324|prophase, ! cell volume homeostasis GO:0006884 5 5 0,000 0,0173256 0,09735085 ! regulation of epidermal growth factor receptor activity GO:0007176 5 5 0,000 0,0173256 0,09705495 GO:0010469|regulation of receptor activity, ! regulation of long-term neuronal synaptic plasticity GO:0048169 5 5 0,000 0,0173256 0,09676084 ! CTP metabolic process GO:0046036 5 5 0,000 0,0173256 0,09646852 GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0006241|CTP biosynthetic process, ! Golgi to endosome transport GO:0006895 5 5 0,000 0,0173256 0,09617795 ! GTP metabolic process GO:0046039 5 5 0,000 0,0173256 0,09588913 ! establishment of tissue polarity GO:0007164 5 5 0,000 0,0173256 0,09560203 ! positive regulation of cell-cell adhesion GO:0022409 5 5 0,000 0,0173256 0,09531665 ! regulation of neurotransmitter secretion GO:0046928 5 5 0,000 0,0173256 0,09503297 GO:0001956|positive regulation of neurotransmitter secretion, ! neurotransmitter uptake GO:0001504 5 5 0,000 0,0173256 0,09475098 ! social behavior GO:0035176 5 5 0,000 0,0173256 0,09447065 ! macrophage chemotaxis GO:0048246 6 5 0,000 0,0173256 0,09419197 ! memory GO:0007613 5 5 0,000 0,0173256 0,09391494 ! dopamine receptor signaling pathway GO:0007212 5 5 0,000 0,0173256 0,09363953 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 5 5 0,000 0,0173256 0,09336573 ! membrane hyperpolarization GO:0060081 5 5 0,000 0,0173256 0,09309352 ! response to lipid GO:0033993 5 5 0,000 0,0173256 0,0928229 ! erythrocyte maturation GO:0043249 5 5 0,000 0,0173256 0,09255385 ! hippocampus development GO:0021766 6 5 0,000 0,0173256 0,09228635 ! regulation of carbohydrate biosynthetic process GO:0043255 5 5 0,000 0,0173256 0,0920204 ! glucocorticoid metabolic process GO:0008211 5 5 0,000 0,0173256 0,09175597 ! middle ear morphogenesis GO:0042474 5 5 0,000 0,0173256 0,09149306 ! amyloid precursor protein catabolic process GO:0042987 5 5 0,000 0,0173256 0,09123165 ! mechanosensory behavior GO:0007638 5 5 0,000 0,0173256 0,09097173 ! negative regulation of endocytosis GO:0045806 5 5 0,000 0,0173256 0,09071329 ! response to interferon-gamma GO:0034341 5 5 0,000 0,0173256 0,09045631 ! pseudouridine synthesis GO:0001522 5 5 0,000 0,0173256 0,09020079 ! endocrine pancreas development GO:0031018 5 5 0,000 0,0173256 0,0899467 ! pH reduction GO:0045851 5 5 0,000 0,0173256 0,08969404 GO:0051452|intracellular pH reduction, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 5 5 0,000 0,0173256 0,0894428 ! lipopolysaccharide metabolic process GO:0008653 5 5 0,000 0,0173256 0,08919296 ! positive regulation of chemokine biosynthetic process GO:0045080 5 5 0,000 0,0173256 0,08894451 ! sphingoid biosynthetic process GO:0046520 5 5 0,000 0,0173256 0,08869744 GO:0046513|ceramide biosynthetic process, ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 5 5 0,000 0,0173256 0,08845174 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! thymic T cell selection GO:0045061 5 5 0,000 0,0173256 0,0882074 ! photoreceptor cell maintenance GO:0045494 5 5 0,000 0,0173256 0,0879644 ! adrenal gland development GO:0030325 5 5 0,000 0,0173256 0,08772274 ! regulation of cardiac muscle hypertrophy GO:0010611 5 5 0,000 0,0173256 0,08748241 GO:0010612|regulation of cardiac muscle adaptation, GO:0014743|regulation of muscle hypertrophy, GO:0043502|regulation of muscle adaptation, ! melanocyte differentiation GO:0030318 5 5 0,000 0,0173256 0,08724338 GO:0050931|pigment cell differentiation, ! ovulation GO:0030728 5 5 0,000 0,0173256 0,08700566 ! astrocyte differentiation GO:0048708 5 5 0,000 0,0173256 0,08676924 ! mitochondrial respiratory chain complex assembly GO:0033108 5 5 0,000 0,0173256 0,08653409 GO:0032981|mitochondrial respiratory chain complex I assembly, GO:0010257|NADH dehydrogenase complex assembly, ! pituitary gland development GO:0021983 5 5 0,000 0,0173256 0,08630021 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 5 5 0,000 0,0173256 0,0860676 GO:0033135|regulation of peptidyl-serine phosphorylation, ! tyrosine metabolic process GO:0006570 5 5 0,000 0,0173256 0,08583623 ! cytoskeletal anchoring at plasma membrane GO:0007016 6 5 0,000 0,0173256 0,08560611 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 5 5 0,000 0,0173256 0,08537722 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, GO:0009164|nucleoside catabolic process, ! microtubule nucleation GO:0007020 5 5 0,000 0,0173256 0,08514954 ! regulation of interleukin-6 biosynthetic process GO:0045408 5 5 0,000 0,0173256 0,08492308 ! regulation of interleukin-8 biosynthetic process GO:0045414 5 5 0,000 0,0173256 0,08469782 ! indolalkylamine metabolic process GO:0006586 5 5 0,000 0,0173256 0,08447375 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! muscle cell migration GO:0014812 5 5 0,000 0,0173256 0,08425087 ! phasic smooth muscle contraction GO:0014821 5 5 0,000 0,0173256 0,08402915 ! central nervous system neuron axonogenesis GO:0021955 6 5 0,000 0,0173256 0,08380861 GO:0021952|central nervous system projection neuron axonogenesis, ! sister chromatid cohesion GO:0007062 5 5 0,000 0,0173256 0,08358921 ! response to ATP GO:0033198 5 5 0,000 0,0173256 0,08337096 ! regulation of type I interferon production GO:0032479 5 5 0,000 0,0173256 0,08315385 ! regulation of appetite GO:0032098 5 5 0,000 0,0173256 0,08293787 GO:0032095|regulation of response to food, ! vesicle fusion GO:0006906 5 5 0,000 0,0173256 0,082723 ! paraxial mesoderm development GO:0048339 5 5 0,000 0,0173256 0,08250925 ! regulation of the force of heart contraction GO:0002026 5 5 0,000 0,0173256 0,08229659 ! maintenance of protein location in nucleus GO:0051457 5 5 0,000 0,0173256 0,08208504 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,0173256 0,08187456 ! receptor clustering GO:0043113 5 5 0,000 0,0173256 0,08166516 ! neurotransmitter biosynthetic process GO:0042136 6 5 0,000 0,0173256 0,08145683 ! fear response GO:0042596 5 5 0,000 0,0173256 0,08124956 ! actin cytoskeleton reorganization GO:0031532 5 5 0,000 0,0173256 0,08104335 ! lens development in camera-type eye GO:0002088 5 5 0,000 0,0173256 0,08083817 ! retinol metabolic process GO:0042572 5 5 0,000 0,0173256 0,08063404 ! corticosteroid receptor signaling pathway GO:0031958 5 5 0,000 0,0173256 0,08043093 GO:0042921|glucocorticoid receptor signaling pathway, ! temperature homeostasis GO:0001659 5 5 0,000 0,0173256 0,08022884 ! positive regulation of exocytosis GO:0045921 6 5 0,000 0,0173256 0,08002777 ! parturition GO:0007567 5 5 0,000 0,0173256 0,0798277 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,0173256 0,07962863 ! Schwann cell differentiation GO:0014037 5 5 0,000 0,0173256 0,07943054 ! acyl-CoA metabolic process GO:0006637 5 5 0,000 0,0173256 0,07923345 ! wound healing, spreading of epidermal cells GO:0035313 5 5 0,000 0,0173256 0,07903732 ! regulation of gliogenesis GO:0014013 5 5 0,000 0,0173256 0,07884217 GO:0045685|regulation of glial cell differentiation, ! positive regulation of peptide secretion GO:0002793 5 5 0,000 0,0173256 0,07864798 ! response to UV-B GO:0010224 5 5 0,000 0,0173256 0,07845474 ! oligodendrocyte development GO:0014003 5 5 0,000 0,0173256 0,07826245 ! hyaluronan metabolic process GO:0030212 5 5 0,000 0,0173256 0,0780711 ! activated T cell proliferation GO:0050798 5 5 0,000 0,0173256 0,07788068 ! interaction with symbiont GO:0051702 5 5 0,000 0,0173256 0,07769119 ! cellular extravasation GO:0045123 5 5 0,000 0,0173256 0,07750262 ! positive regulation of axonogenesis GO:0050772 5 5 0,000 0,0173256 0,07731496 ! peptidyl-asparagine modification GO:0018196 5 5 0,000 0,0173256 0,07712821 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! positive regulation of phagocytosis GO:0050766 5 5 0,000 0,0173256 0,07694236 ! regulation of insulin receptor signaling pathway GO:0046626 5 5 0,000 0,0173256 0,0767574 ! antigen processing and presentation of exogenous antigen GO:0019884 5 5 0,000 0,0173256 0,07657333 ! enucleate erythrocyte differentiation GO:0043353 6 5 0,000 0,0173256 0,07639014 ! response to amine stimulus GO:0014075 5 5 0,000 0,0173256 0,07620783 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 5 5 0,000 0,0173256 0,07602638 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 5 5 0,000 0,0173256 0,07584579 ! synaptic vesicle exocytosis GO:0016079 6 5 0,000 0,0173256 0,07566606 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 5 5 0,000 0,0173256 0,07548718 ! glycosylceramide metabolic process GO:0006677 5 5 0,000 0,0173256 0,07530915 ! neuron recognition GO:0008038 5 5 0,000 0,0173256 0,07513195 ! negative regulation of focal adhesion formation GO:0051895 6 5 0,000 0,0173256 0,07495558 ! decidualization GO:0046697 5 5 0,000 0,0173256 0,07478004 ! hair follicle maturation GO:0048820 5 5 0,000 0,0173256 0,07460532 ! phosphatidylinositol biosynthetic process GO:0006661 5 5 0,000 0,0173256 0,07443142 ! regulation of mitochondrial membrane potential GO:0051881 5 5 0,000 0,0173256 0,07425832 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 0,0173256 0,07408603 GO:0009155|purine deoxyribonucleotide catabolic process, ! regulation of interleukin-12 production GO:0032655 5 5 0,000 0,0173256 0,07391453 ! positive regulation of interleukin-6 production GO:0032755 5 5 0,000 0,0173256 0,07374383 ! postreplication repair GO:0006301 5 5 0,000 0,0173256 0,07357391 ! spinal cord motor neuron differentiation GO:0021522 5 5 0,000 0,0173256 0,07340478 GO:0021517|ventral spinal cord development, ! cellular pigmentation GO:0033059 5 5 0,000 0,0173256 0,07323642 ! histone methylation GO:0016571 5 5 0,000 0,0173256 0,07306883 ! DNA methylation GO:0006306 5 5 0,000 0,0173256 0,07290201 GO:0006305|DNA alkylation, ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,0173256 0,07273594 ! T cell lineage commitment GO:0002360 5 5 0,000 0,0173256 0,07257063 ! positive regulation of immunoglobulin mediated immune response GO:0002891 5 5 0,000 0,0173256 0,07240607 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of interferon-gamma production GO:0032729 5 5 0,000 0,0173256 0,07224226 ! negative regulation of tumor necrosis factor production GO:0032720 5 5 0,000 0,0173256 0,07207918 ! intracellular cholesterol transport GO:0032367 5 5 0,000 0,0173256 0,07191684 GO:0032366|intracellular sterol transport, ! regulation of mast cell activation GO:0033003 5 5 0,000 0,0173256 0,07175523 ! morphogenesis of a polarized epithelium GO:0001738 5 5 0,000 0,0173256 0,07159435 ! regulation of transcription from RNA polymerase III promoter GO:0006359 5 5 0,000 0,0173256 0,07143418 ! regulation of inflammatory response to antigenic stimulus GO:0002861 5 5 0,000 0,0173256 0,07127473 ! sterol catabolic process GO:0016127 5 5 0,000 0,0173256 0,07111599 GO:0006707|cholesterol catabolic process, ! negative regulation of oxidoreductase activity GO:0051354 5 5 0,000 0,0173256 0,07095795 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 5 5 0,000 0,0173256 0,07080062 ! detection of biotic stimulus GO:0009595 5 5 0,000 0,0173256 0,07064398 ! regulation of immune response to tumor cell GO:0002837 5 5 0,000 0,0173256 0,07048803 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 5 5 0,000 0,0173256 0,07033277 ! zymogen activation GO:0031638 5 5 0,000 0,0173256 0,0701782 ! positive regulation of interleukin-1 beta secretion GO:0050718 5 5 0,000 0,0173256 0,0700243 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 5 5 0,000 0,0173256 0,06987107 GO:0002820|negative regulation of adaptive immune response, ! cellular response to nutrient GO:0031670 5 5 0,000 0,0173256 0,06971851 ! negative regulation of neuroblast proliferation GO:0007406 5 5 0,000 0,0173256 0,06956662 ! peptidyl-histidine modification GO:0018202 5 5 0,000 0,0173256 0,06941539 ! nucleosome positioning GO:0016584 5 5 0,000 0,0173256 0,06926481 ! regulation of isotype switching GO:0045191 5 5 0,000 0,0173256 0,06911489 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 5 5 0,000 0,0173256 0,06896561 ! negative regulation of neurological system process GO:0031645 5 5 0,000 0,0173256 0,06881698 ! regulation of myoblast differentiation GO:0045661 5 5 0,000 0,0173256 0,06866899 ! glutathione biosynthetic process GO:0006750 5 5 0,000 0,0173256 0,06852163 ! NADPH regeneration GO:0006740 5 5 0,000 0,0173256 0,0683749 GO:0006098|pentose-phosphate shunt, ! positive regulation of epidermis development GO:0045684 5 5 0,000 0,0173256 0,0682288 ! positive regulation of leukocyte chemotaxis GO:0002690 5 5 0,000 0,0173256 0,06808332 GO:0002688|regulation of leukocyte chemotaxis, ! musculoskeletal movement GO:0050881 5 5 0,000 0,0173256 0,06793847 GO:0050879|multicellular organismal movement, ! neuromuscular process controlling posture GO:0050884 5 5 0,000 0,0173256 0,06779422 ! sarcomere organization GO:0045214 5 5 0,000 0,0173256 0,06765059 ! regulation of epidermal cell differentiation GO:0045604 5 5 0,000 0,0173256 0,06750757 ! activation of NF-kappaB-inducing kinase activity GO:0007250 5 5 0,000 0,0173256 0,06736515 ! negative regulation of glucose transport GO:0010829 5 5 0,000 0,0173256 0,06722332 GO:0046325|negative regulation of glucose import, ! positive regulation of T-helper cell differentiation GO:0045624 5 5 0,000 0,0173256 0,0670821 GO:0045622|regulation of T-helper cell differentiation, ! oocyte differentiation GO:0009994 5 5 0,000 0,0173256 0,06694147 GO:0048599|oocyte development, ! dopamine biosynthetic process GO:0042416 5 5 0,000 0,0173256 0,06680142 ! regulation of protein homodimerization activity GO:0043496 6 5 0,000 0,0173256 0,06666196 ! spleen development GO:0048536 5 5 0,000 0,0173256 0,06652308 ! male genitalia development GO:0030539 5 5 0,000 0,0173256 0,06638478 ! nicotinamide nucleotide biosynthetic process GO:0019359 5 5 0,000 0,0173256 0,06624705 ! quaternary ammonium group transport GO:0015697 5 5 0,000 0,0173256 0,06610989 ! thyroid hormone metabolic process GO:0042403 5 5 0,000 0,0173256 0,0659733 ! leukocyte mediated cytotoxicity GO:0001909 5 5 0,000 0,0173256 0,06583728 ! positive regulation of viral reproduction GO:0048524 5 5 0,000 0,0173256 0,06570181 ! removal of superoxide radicals GO:0019430 6 5 0,000 0,0173256 0,0655669 ! myeloid cell homeostasis GO:0002262 5 5 0,000 0,0173256 0,06543254 ! regulation of fatty acid oxidation GO:0046320 5 5 0,000 0,0173256 0,06529873 ! regulation of Rac protein signal transduction GO:0035020 5 5 0,000 0,0173256 0,06516547 ! ATP catabolic process GO:0006200 5 5 0,000 0,0173256 0,06503275 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,0173256 0,06490057 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 5 5 0,000 0,0173256 0,06476892 ! blastocyst formation GO:0001825 5 5 0,000 0,0173256 0,06463781 ! regulation of fibrinolysis GO:0051917 5 5 0,000 0,0173256 0,06450723 ! embryonic gut development GO:0048566 5 5 0,000 0,0173256 0,06437718 ! negative regulation of organic acid transport GO:0032891 5 5 0,000 0,0173256 0,06424764 ! pyrimidine base metabolic process GO:0006206 5 5 0,000 0,0173256 0,06411863 ! activation of innate immune response GO:0002218 5 5 0,000 0,0173256 0,06399014 GO:0002758|innate immune response-activating signal transduction, ! catecholamine transport GO:0051937 5 5 0,000 0,0173256 0,06386216 ! negative regulation of blood vessel endothelial cell migration GO:0043537 5 5 0,000 0,0173256 0,06373469 ! regulation of NF-kappaB import into nucleus GO:0042345 5 5 0,000 0,0173256 0,06360773 ! muscle adaptation GO:0043500 5 5 0,000 0,0173256 0,06348127 ! positive regulation of actin filament bundle formation GO:0032233 5 5 0,000 0,0173256 0,06335532 ! embryonic heart tube development GO:0035050 5 5 0,000 0,0173256 0,06322986 ! cardiac cell differentiation GO:0035051 6 5 0,000 0,0173256 0,0631049 ! positive regulation of homeostatic process GO:0032846 5 5 0,000 0,0173256 0,06298043 ! defense response to fungus GO:0050832 5 5 0,000 0,0173256 0,06285645 ! lysogeny GO:0030069 5 5 0,000 0,0173256 0,06273296 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 5 5 0,000 0,0173256 0,06260996 ! B cell receptor signaling pathway GO:0050853 5 5 0,000 0,0173256 0,06248743 ! positive regulation of smooth muscle contraction GO:0045987 5 5 0,000 0,0173256 0,06236539 ! response to nicotine GO:0035094 5 5 0,000 0,0173256 0,06224382 ! establishment of cell polarity GO:0030010 5 5 0,000 0,0173256 0,06212272 ! mitochondrion localization GO:0051646 5 5 0,000 0,0173256 0,06200209 ! regulation of synapse structure and activity GO:0050803 5 5 0,000 0,0173256 0,06188194 ! cellular respiration GO:0045333 62 61 1,000 0,01882941 0,06712304 ! positive regulation of cellular protein metabolic process GO:0032270 61 61 1,000 0,01882941 0,06699346 ! glucose metabolic process GO:0006006 63 63 1,000 0,02001023 0,07105751 ! regulation of response to external stimulus GO:0032101 65 64 1,000 0,02061212 0,07305409 ! regulation of cytoskeleton organization GO:0051493 66 64 1,000 0,02061212 0,07291387 ! positive regulation of protein metabolic process GO:0051247 64 64 1,000 0,02061212 0,07277419 ! axon extension GO:0048675 7 6 0,000 0,02075603 0,07314217 ! oligosaccharide biosynthetic process GO:0009312 6 6 0,000 0,02075603 0,07300259 ! tRNA modification GO:0006400 6 6 0,000 0,02075603 0,07286353 ! somatic diversification of immune receptors via somatic mutation GO:0002566 6 6 0,000 0,02075603 0,07272501 GO:0016446|somatic hypermutation of immunoglobulin genes, ! 'de novo' posttranslational protein folding GO:0051084 6 6 0,000 0,02075603 0,07258701 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 6 6 0,000 0,02075603 0,07244954 ! negative regulation of cellular catabolic process GO:0031330 6 6 0,000 0,02075603 0,07231258 ! regulation of S phase GO:0033261 6 6 0,000 0,02075603 0,07217614 ! myotube differentiation GO:0014902 6 6 0,000 0,02075603 0,07204022 ! regulation of B cell proliferation GO:0030888 6 6 0,000 0,02075603 0,0719048 ! bone remodeling GO:0046849 6 6 0,000 0,02075603 0,0717699 ! N-glycan processing GO:0006491 6 6 0,000 0,02075603 0,0716355 ! glycosaminoglycan catabolic process GO:0006027 6 6 0,000 0,02075603 0,0715016 ! negative regulation of JAK-STAT cascade GO:0046426 6 6 0,000 0,02075603 0,0713682 ! retina development in camera-type eye GO:0060041 6 6 0,000 0,02075603 0,0712353 ! RNA methylation GO:0001510 6 6 0,000 0,02075603 0,07110289 ! regulation of activated T cell proliferation GO:0046006 6 6 0,000 0,02075603 0,07097098 ! artery development GO:0060840 6 6 0,000 0,02075603 0,07083955 GO:0048844|artery morphogenesis, ! positive regulation of neurotransmitter transport GO:0051590 6 6 0,000 0,02075603 0,07070861 ! bile acid metabolic process GO:0008206 6 6 0,000 0,02075603 0,07057815 ! androgen metabolic process GO:0008209 6 6 0,000 0,02075603 0,07044817 ! estrogen metabolic process GO:0008210 6 6 0,000 0,02075603 0,07031867 ! limbic system development GO:0021761 7 6 0,000 0,02075603 0,07018964 ! cytoplasmic sequestering of transcription factor GO:0042994 6 6 0,000 0,02075603 0,07006109 ! positive regulation of transcription factor import into nucleus GO:0042993 6 6 0,000 0,02075603 0,06993301 ! positive regulation of heart contraction GO:0045823 6 6 0,000 0,02075603 0,06980539 ! positive regulation of gene expression, epigenetic GO:0045815 6 6 0,000 0,02075603 0,06967824 ! pathogenesis GO:0009405 6 6 0,000 0,02075603 0,06955156 ! negative regulation of protein amino acid phosphorylation GO:0001933 6 6 0,000 0,02075603 0,06942533 ! positive regulation of cell growth GO:0030307 6 6 0,000 0,02075603 0,06929956 ! ribonucleoside triphosphate catabolic process GO:0009203 6 6 0,000 0,02075603 0,06917424 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! regulation of chemokine biosynthetic process GO:0045073 6 6 0,000 0,02075603 0,06904938 ! nerve growth factor receptor signaling pathway GO:0048011 6 6 0,000 0,02075603 0,06892497 ! inositol phosphate-mediated signaling GO:0048016 6 6 0,000 0,02075603 0,068801 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 6 6 0,000 0,02075603 0,06867748 ! arginine metabolic process GO:0006525 6 6 0,000 0,02075603 0,0685544 GO:0006527|arginine catabolic process, ! regulation of catecholamine secretion GO:0050433 6 6 0,000 0,02075603 0,06843176 ! oligodendrocyte differentiation GO:0048709 6 6 0,000 0,02075603 0,06830956 ! glutamate catabolic process GO:0006538 7 6 0,000 0,02075603 0,0681878 ! telomere maintenance via telomerase GO:0007004 6 6 0,000 0,02075603 0,06806647 GO:0010833|telomere maintenance via telomere lengthening, ! L-phenylalanine metabolic process GO:0006558 6 6 0,000 0,02075603 0,06794557 GO:0006559|L-phenylalanine catabolic process, ! glucan biosynthetic process GO:0009250 6 6 0,000 0,02075603 0,0678251 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 6 6 0,000 0,02075603 0,06770505 ! ER overload response GO:0006983 6 6 0,000 0,02075603 0,06758543 ! V(D)J recombination GO:0033151 6 6 0,000 0,02075603 0,06746624 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 0,02075603 0,06734746 ! negative regulation of T cell proliferation GO:0042130 6 6 0,000 0,02075603 0,0672291 GO:0070667|negative regulation of mast cell proliferation, ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 6 6 0,000 0,02075603 0,06711115 ! negative regulation of endothelial cell migration GO:0010596 6 6 0,000 0,02075603 0,06699362 ! regulation of heart rate GO:0002027 6 6 0,000 0,02075603 0,0668765 ! lipid digestion GO:0044241 6 6 0,000 0,02075603 0,06675978 ! asymmetric protein localization GO:0008105 6 6 0,000 0,02075603 0,06664348 ! retrograde transport, endosome to Golgi GO:0042147 6 6 0,000 0,02075603 0,06652758 ! phagocytosis, engulfment GO:0006911 6 6 0,000 0,02075603 0,06641208 ! Rac protein signal transduction GO:0016601 6 6 0,000 0,02075603 0,06629698 ! regulation of calcium ion transport into cytosol GO:0010522 6 6 0,000 0,02075603 0,06618228 ! ruffle organization GO:0031529 6 6 0,000 0,02075603 0,06606797 ! peptidyl-serine phosphorylation GO:0018105 6 6 0,000 0,02075603 0,06595406 ! preassembly of GPI anchor in ER membrane GO:0016254 6 6 0,000 0,02075603 0,06584054 ! retinoic acid metabolic process GO:0042573 6 6 0,000 0,02075603 0,06572742 ! neutral amino acid transport GO:0015804 6 6 0,000 0,02075603 0,06561468 ! L-amino acid transport GO:0015807 6 6 0,000 0,02075603 0,06550232 ! bone mineralization GO:0030282 6 6 0,000 0,02075603 0,06539035 GO:0031214|biomineral formation, ! rRNA modification GO:0000154 6 6 0,000 0,02075603 0,06527876 ! negative regulation of ossification GO:0030279 6 6 0,000 0,02075603 0,06516756 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 6 6 0,000 0,02075603 0,06505673 GO:0002717|positive regulation of natural killer cell mediated immunity, GO:0002715|regulation of natural killer cell mediated immunity, GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 7 6 0,000 0,02075603 0,06494627 ! purine base biosynthetic process GO:0009113 6 6 0,000 0,02075603 0,0648362 ! G1 DNA damage checkpoint GO:0031571 6 6 0,000 0,02075603 0,06472649 ! negative regulation of axonogenesis GO:0050771 7 6 0,000 0,02075603 0,06461716 ! regulation of phagocytosis GO:0050764 6 6 0,000 0,02075603 0,06450819 ! regulation of organ growth GO:0046620 6 6 0,000 0,02075603 0,06439959 ! regulation of circadian rhythm GO:0042752 6 6 0,000 0,02075603 0,06429135 ! positive regulation of T cell mediated immunity GO:0002711 6 6 0,000 0,02075603 0,06418348 ! response to dsRNA GO:0043331 6 6 0,000 0,02075603 0,06407597 ! DNA unwinding during replication GO:0006268 6 6 0,000 0,02075603 0,06396882 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 6 6 0,000 0,02075603 0,06386203 GO:0009147|pyrimidine nucleoside triphosphate metabolic process, ! regulation of T cell differentiation in the thymus GO:0033081 6 6 0,000 0,02075603 0,06375559 ! genitalia development GO:0048806 6 6 0,000 0,02075603 0,06364951 ! sphingomyelin metabolic process GO:0006684 6 6 0,000 0,02075603 0,06354378 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 6 6 0,000 0,02075603 0,0634384 ! phosphoinositide 3-kinase cascade GO:0014065 6 6 0,000 0,02075603 0,06333337 ! positive regulation of B cell differentiation GO:0045579 6 6 0,000 0,02075603 0,06322869 ! multicellular organismal aging GO:0010259 6 6 0,000 0,02075603 0,06312435 ! regulation of focal adhesion formation GO:0051893 7 6 0,000 0,02075603 0,06302036 ! respiratory chain complex IV assembly GO:0008535 6 6 0,000 0,02075603 0,0629167 ! erythrocyte development GO:0048821 6 6 0,000 0,02075603 0,06281339 ! renal water homeostasis GO:0003091 6 6 0,000 0,02075603 0,06271042 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 6 6 0,000 0,02075603 0,06260778 GO:0043372|positive regulation of CD4-positive, alpha beta T cell differentiation, ! ribosomal large subunit biogenesis GO:0042273 6 6 0,000 0,02075603 0,06250548 ! regulation of Rho GTPase activity GO:0032319 6 6 0,000 0,02075603 0,06240352 ! ribosome assembly GO:0042255 6 6 0,000 0,02075603 0,06230188 ! positive regulation of Ras GTPase activity GO:0032320 6 6 0,000 0,02075603 0,06220058 ! diencephalon development GO:0021536 6 6 0,000 0,02075603 0,0620996 ! fucose catabolic process GO:0019317 6 6 0,000 0,02075603 0,06199896 GO:0042355|L-fucose catabolic process, ! nitric oxide metabolic process GO:0046209 6 6 0,000 0,02075603 0,06189863 GO:0006809|nitric oxide biosynthetic process, ! protein sumoylation GO:0016925 6 6 0,000 0,02075603 0,06179864 ! regulation of lipid transport GO:0032368 6 6 0,000 0,02075603 0,06169896 ! regulation of cell division GO:0051302 6 6 0,000 0,02075603 0,06159961 ! positive regulation of interleukin-1 secretion GO:0050716 6 6 0,000 0,02075603 0,06150057 ! cellular metabolic compound salvage GO:0043094 6 6 0,000 0,02075603 0,06140186 ! regulation of T-helper 2 type immune response GO:0002828 6 6 0,000 0,02075603 0,06130345 ! salivary gland morphogenesis GO:0007435 6 6 0,000 0,02075603 0,06120537 ! neuroblast proliferation GO:0007405 6 6 0,000 0,02075603 0,0611076 ! regulation of interleukin-1 beta secretion GO:0050706 6 6 0,000 0,02075603 0,06101014 ! nitric oxide mediated signal transduction GO:0007263 6 6 0,000 0,02075603 0,06091299 ! regulation of glucose transport GO:0010827 6 6 0,000 0,02075603 0,06081615 GO:0046324|regulation of glucose import, ! intestinal absorption GO:0050892 6 6 0,000 0,02075603 0,06071961 ! methionine biosynthetic process GO:0009086 6 6 0,000 0,02075603 0,06062338 ! glutamine family amino acid biosynthetic process GO:0009084 6 6 0,000 0,02075603 0,06052746 ! serine family amino acid biosynthetic process GO:0009070 6 6 0,000 0,02075603 0,06043184 ! thymus development GO:0048538 6 6 0,000 0,02075603 0,06033652 ! lymph node development GO:0048535 6 6 0,000 0,02075603 0,06024151 ! organic cation transport GO:0015695 6 6 0,000 0,02075603 0,06014679 ! negative regulation of BMP signaling pathway GO:0030514 6 6 0,000 0,02075603 0,06005236 ! regulation of RNA splicing GO:0043484 6 6 0,000 0,02075603 0,05995824 ! positive regulation of JNK cascade GO:0046330 7 6 0,000 0,02075603 0,05986441 ! sperm-egg recognition GO:0035036 7 6 0,000 0,02075603 0,05977087 GO:0007339|binding of sperm to zona pellucida, ! germ cell migration GO:0008354 6 6 0,000 0,02075603 0,05967762 ! establishment or maintenance of apical/basal cell polarity GO:0035088 6 6 0,000 0,02075603 0,05958467 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 6 6 0,000 0,02075603 0,059492 ! alditol metabolic process GO:0019400 6 6 0,000 0,02075603 0,05939962 ! regulation of synaptic transmission, GABAergic GO:0032228 6 6 0,000 0,02075603 0,05930753 ! regulation of amino acid transport GO:0051955 6 6 0,000 0,02075603 0,05921572 ! maternal placenta development GO:0001893 6 6 0,000 0,02075603 0,0591242 ! negative regulation of immune effector process GO:0002698 6 6 0,000 0,02075603 0,05903296 ! striated muscle tissue development GO:0014706 69 67 1,000 0,02246304 0,0637895 ! response to radiation GO:0009314 70 68 1,000 0,02309492 0,06548297 ! regionalization GO:0003002 70 69 1,000 0,02373415 0,06719208 ! respiratory burst GO:0045730 7 7 0,000 0,02417497 0,06833509 ! negative regulation of cell projection organization GO:0031345 8 7 0,000 0,02417497 0,06823044 ! positive regulation of blood pressure GO:0045777 7 7 0,000 0,02417497 0,06812611 ! pteridine and derivative biosynthetic process GO:0042559 7 7 0,000 0,02417497 0,0680221 ! double-strand break repair via homologous recombination GO:0000724 7 7 0,000 0,02417497 0,06791841 GO:0000725|recombinational repair, ! positive regulation of GTPase activity GO:0043547 7 7 0,000 0,02417497 0,06781504 ! SMAD protein nuclear translocation GO:0007184 7 7 0,000 0,02417497 0,06771197 ! cellular protein complex disassembly GO:0043624 8 7 0,000 0,02417497 0,06760922 GO:0043241|protein complex disassembly, ! hair follicle morphogenesis GO:0031069 7 7 0,000 0,02417497 0,06750679 ! gene silencing by RNA GO:0031047 7 7 0,000 0,02417497 0,06740466 ! regulation of receptor-mediated endocytosis GO:0048259 7 7 0,000 0,02417497 0,06730284 ! regulation of neurotransmitter transport GO:0051588 7 7 0,000 0,02417497 0,06720133 ! keratinocyte proliferation GO:0043616 7 7 0,000 0,02417497 0,06710012 ! axis specification GO:0009798 7 7 0,000 0,02417497 0,06699922 ! negative regulation of muscle cell differentiation GO:0051148 7 7 0,000 0,02417497 0,06689862 ! visual behavior GO:0007632 7 7 0,000 0,02417497 0,06679832 GO:0008542|visual learning, ! startle response GO:0001964 7 7 0,000 0,02417497 0,06669832 ! amyloid precursor protein metabolic process GO:0042982 7 7 0,000 0,02417497 0,06659862 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 8 7 0,000 0,02417497 0,06649922 ! positive regulation of lipid metabolic process GO:0045834 7 7 0,000 0,02417497 0,06640012 ! negative regulation of lipid metabolic process GO:0045833 7 7 0,000 0,02417497 0,06630131 ! regulation of interferon-gamma biosynthetic process GO:0045072 7 7 0,000 0,02417497 0,06620279 ! endothelial cell differentiation GO:0045446 7 7 0,000 0,02417497 0,06610457 ! negative regulation of striated muscle development GO:0045843 7 7 0,000 0,02417497 0,06600664 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 7 7 0,000 0,02417497 0,06590899 ! digestive system development GO:0055123 7 7 0,000 0,02417497 0,06581164 GO:0048546|digestive tract morphogenesis, GO:0048547|gut morphogenesis, ! regulation of exit from mitosis GO:0007096 7 7 0,000 0,02417497 0,06571457 ! protein targeting to ER GO:0045047 8 7 0,000 0,02417497 0,06561779 ! cell differentiation in spinal cord GO:0021515 7 7 0,000 0,02417497 0,06552129 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 7 7 0,000 0,02417497 0,06542508 ! endoderm development GO:0007492 7 7 0,000 0,02417497 0,06532915 ! regulation of defense response to virus GO:0050688 7 7 0,000 0,02417497 0,0652335 ! glycolipid biosynthetic process GO:0009247 7 7 0,000 0,02417497 0,06513813 GO:0006688|glycosphingolipid biosynthetic process, ! regulation of mRNA processing GO:0050684 7 7 0,000 0,02417497 0,06504303 ! response to hexose stimulus GO:0009746 7 7 0,000 0,02417497 0,06494822 GO:0034284|response to monosaccharide stimulus, GO:0009749|response to glucose stimulus, ! membrane protein ectodomain proteolysis GO:0006509 7 7 0,000 0,02417497 0,06485368 GO:0033619|membrane protein proteolysis, ! positive regulation of survival gene product expression GO:0045885 7 7 0,000 0,02417497 0,06475942 ! regulation of skeletal muscle fiber development GO:0048742 7 7 0,000 0,02417497 0,06466543 ! negative regulation of lymphocyte proliferation GO:0050672 7 7 0,000 0,02417497 0,06457171 GO:0032945|negative regulation of mononuclear cell proliferation, GO:0070664|negative regulation of leukocyte proliferation, ! cardiac muscle tissue development GO:0048738 7 7 0,000 0,02417497 0,06447826 ! nucleotide-sugar metabolic process GO:0009225 7 7 0,000 0,02417497 0,06438508 ! complement activation, alternative pathway GO:0006957 7 7 0,000 0,02417497 0,06429218 ! arachidonic acid secretion GO:0050482 7 7 0,000 0,02417497 0,06419954 GO:0032309|icosanoid secretion, ! polyamine biosynthetic process GO:0006596 7 7 0,000 0,02417497 0,06410716 ! response to X-ray GO:0010165 7 7 0,000 0,02417497 0,06401506 ! regulation of intracellular pH GO:0051453 7 7 0,000 0,02417497 0,06392321 ! UV protection GO:0009650 7 7 0,000 0,02417497 0,06383163 ! DNA integration GO:0015074 7 7 0,000 0,02417497 0,06374031 ! myofibril assembly GO:0030239 7 7 0,000 0,02417497 0,06364926 GO:0055002|striated muscle cell development, ! positive regulation of muscle contraction GO:0045933 7 7 0,000 0,02417497 0,06355846 ! negative regulation of muscle contraction GO:0045932 7 7 0,000 0,02417497 0,06346792 ! chondroitin sulfate biosynthetic process GO:0030206 7 7 0,000 0,02417497 0,06337764 GO:0030204|chondroitin sulfate metabolic process, ! regulation of exocytosis GO:0017157 8 7 0,000 0,02417497 0,06328761 ! phosphatidylcholine biosynthetic process GO:0006656 7 7 0,000 0,02417497 0,06319784 ! heparan sulfate proteoglycan metabolic process GO:0030201 7 7 0,000 0,02417497 0,06310833 GO:0015012|heparan sulfate proteoglycan biosynthetic process, ! stem cell development GO:0048864 7 7 0,000 0,02417497 0,06301906 GO:0019827|stem cell maintenance, ! alpha-beta T cell differentiation GO:0046632 7 7 0,000 0,02417497 0,06293005 ! negative regulation of myeloid leukocyte differentiation GO:0002762 7 7 0,000 0,02417497 0,0628413 ! NLS-bearing substrate import into nucleus GO:0006607 7 7 0,000 0,02417497 0,06275279 ! axon cargo transport GO:0008088 7 7 0,000 0,02417497 0,06266453 ! eating behavior GO:0042755 7 7 0,000 0,02417497 0,06257652 ! RNA-dependent DNA replication GO:0006278 7 7 0,000 0,02417497 0,06248875 ! purine nucleoside triphosphate catabolic process GO:0009146 7 7 0,000 0,02417497 0,06240123 ! regulation of interleukin-8 production GO:0032677 7 7 0,000 0,02417497 0,06231396 ! purine ribonucleotide catabolic process GO:0009154 7 7 0,000 0,02417497 0,06222693 ! ribosomal small subunit biogenesis GO:0042274 7 7 0,000 0,02417497 0,06214014 ! cranial nerve development GO:0021545 7 7 0,000 0,02417497 0,06205359 ! protein import into peroxisome matrix GO:0016558 7 7 0,000 0,02417497 0,06196729 ! induction of an organ GO:0001759 7 7 0,000 0,02417497 0,06188122 ! leukocyte activation during immune response GO:0002366 7 7 0,000 0,02417497 0,06179539 GO:0002263|cell activation during immune response, ! response to estradiol stimulus GO:0032355 7 7 0,000 0,02417497 0,0617098 ! autonomic nervous system development GO:0048483 7 7 0,000 0,02417497 0,06162445 ! intracellular lipid transport GO:0032365 7 7 0,000 0,02417497 0,06153934 ! detection of chemical stimulus GO:0009593 8 7 0,000 0,02417497 0,06145445 ! platelet activation GO:0030168 8 7 0,000 0,02417497 0,06136981 ! negative regulation of cytokine secretion GO:0050710 7 7 0,000 0,02417497 0,06128539 ! regulation of interleukin-1 secretion GO:0050704 7 7 0,000 0,02417497 0,06120121 ! natural killer cell activation GO:0030101 7 7 0,000 0,02417497 0,06111725 ! response to gamma radiation GO:0010332 8 7 0,000 0,02417497 0,06103353 ! NADP metabolic process GO:0006739 7 7 0,000 0,02417497 0,06095004 ! neuromuscular synaptic transmission GO:0007274 7 7 0,000 0,02417497 0,06086677 ! synaptic transmission, cholinergic GO:0007271 7 7 0,000 0,02417497 0,06078374 ! ubiquinone metabolic process GO:0006743 7 7 0,000 0,02417497 0,06070092 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, GO:0042375|quinone cofactor metabolic process, ! regulation of macrophage differentiation GO:0045649 8 7 0,000 0,02417497 0,06061834 ! positive regulation of acute inflammatory response GO:0002675 7 7 0,000 0,02417497 0,06053598 ! regulation of osteoclast differentiation GO:0045670 7 7 0,000 0,02417497 0,06045384 ! multicellular organismal water homeostasis GO:0050891 7 7 0,000 0,02417497 0,06037192 ! regulation of ATPase activity GO:0043462 7 7 0,000 0,02417497 0,06029023 ! cell-cell recognition GO:0009988 8 7 0,000 0,02417497 0,06020876 ! hormone catabolic process GO:0042447 7 7 0,000 0,02417497 0,0601275 ! dopamine metabolic process GO:0042417 7 7 0,000 0,02417497 0,06004647 ! cAMP biosynthetic process GO:0006171 7 7 0,000 0,02417497 0,05996565 ! oxygen transport GO:0015671 7 7 0,000 0,02417497 0,05988505 ! pyridine nucleotide biosynthetic process GO:0019363 7 7 0,000 0,02417497 0,05980467 ! biogenic amine catabolic process GO:0042402 7 7 0,000 0,02417497 0,0597245 ! regulation of axon extension GO:0030516 7 7 0,000 0,02417497 0,05964455 ! cell killing GO:0001906 7 7 0,000 0,02417497 0,05956481 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 7 7 0,000 0,02417497 0,05948529 ! adult feeding behavior GO:0008343 7 7 0,000 0,02417497 0,05940597 ! pyrimidine nucleotide catabolic process GO:0006244 7 7 0,000 0,02417497 0,05932687 ! positive regulation of protein polymerization GO:0032273 7 7 0,000 0,02417497 0,05924798 ! T cell receptor signaling pathway GO:0050852 7 7 0,000 0,02417497 0,05916929 ! negative regulation of T cell activation GO:0050868 7 7 0,000 0,02417497 0,05909082 ! response to cold GO:0009409 7 7 0,000 0,02417497 0,05901255 ! wound healing GO:0042060 74 70 1,000 0,0243807 0,05943601 ! muscle tissue development GO:0060537 72 70 1,000 0,0243807 0,0593575 ! positive regulation of hydrolase activity GO:0051345 72 72 1,000 0,02569548 0,06247596 ! regulation of cytokine production GO:0001817 72 72 1,000 0,02569548 0,06239364 ! coenzyme metabolic process GO:0006732 75 74 1,000 0,02703884 0,06556919 ! regulation of skeletal muscle tissue development GO:0048641 8 8 0,000 0,02758248 0,06679963 ! negative regulation of muscle development GO:0048635 8 8 0,000 0,02758248 0,06671196 ! very-long-chain fatty acid metabolic process GO:0000038 8 8 0,000 0,02758248 0,06662453 ! positive regulation of translation GO:0045727 8 8 0,000 0,02758248 0,06653732 ! positive regulation of cell killing GO:0031343 8 8 0,000 0,02758248 0,06645035 ! superoxide anion generation GO:0042554 8 8 0,000 0,02758248 0,0663636 ! sulfur amino acid biosynthetic process GO:0000097 8 8 0,000 0,02758248 0,06627707 ! cGMP metabolic process GO:0046068 8 8 0,000 0,02758248 0,06619078 GO:0006182|cGMP biosynthetic process, ! thyroid gland development GO:0030878 8 8 0,000 0,02758248 0,0661047 ! 'de novo' protein folding GO:0006458 8 8 0,000 0,02758248 0,06601885 ! dicarboxylic acid transport GO:0006835 8 8 0,000 0,02758248 0,06593322 ! phosphoinositide phosphorylation GO:0046854 8 8 0,000 0,02758248 0,06584782 ! embryonic hindlimb morphogenesis GO:0035116 8 8 0,000 0,02758248 0,06576263 ! zinc ion transport GO:0006829 8 8 0,000 0,02758248 0,06567767 ! embryonic forelimb morphogenesis GO:0035115 8 8 0,000 0,02758248 0,06559292 ! folic acid and derivative biosynthetic process GO:0009396 8 8 0,000 0,02758248 0,0655084 ! regulation of neuronal synaptic plasticity GO:0048168 8 8 0,000 0,02758248 0,06542409 ! cardiac muscle contraction GO:0060048 8 8 0,000 0,02758248 0,06533999 ! lipid localization GO:0010876 8 8 0,000 0,02758248 0,06525612 GO:0019915|lipid storage, ! response to pain GO:0048265 8 8 0,000 0,02758248 0,06517246 ! response to cAMP GO:0051591 8 8 0,000 0,02758248 0,06508901 ! COPI coating of Golgi vesicle GO:0048205 8 8 0,000 0,02758248 0,06500577 GO:0048200|Golgi transport vesicle coating, ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 8 0,000 0,02758248 0,06492275 ! negative regulation of transcription factor import into nucleus GO:0042992 8 8 0,000 0,02758248 0,06483994 ! negative regulation of ion transport GO:0043271 8 8 0,000 0,02758248 0,06475734 ! regulation of response to extracellular stimulus GO:0032104 8 8 0,000 0,02758248 0,06467496 GO:0032107|regulation of response to nutrient levels, ! adult walking behavior GO:0007628 8 8 0,000 0,02758248 0,06459278 ! sensory perception of taste GO:0050909 8 8 0,000 0,02758248 0,06451081 ! organelle fusion GO:0048284 8 8 0,000 0,02758248 0,06442904 ! pancreas development GO:0031016 8 8 0,000 0,02758248 0,06434749 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 8 8 0,000 0,02758248 0,06426614 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! T cell selection GO:0045058 8 8 0,000 0,02758248 0,06418499 ! negative regulation of proteolysis GO:0045861 8 8 0,000 0,02758248 0,06410405 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 8 8 0,000 0,02758248 0,06402332 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 8 8 0,000 0,02758248 0,06394279 ! sperm motility GO:0030317 8 8 0,000 0,02758248 0,06386246 ! regulation of striated muscle contraction GO:0006942 8 8 0,000 0,02758248 0,06378233 ! DNA duplex unwinding GO:0032508 8 8 0,000 0,02758248 0,0637024 GO:0032392|DNA geometric change, ! glycine metabolic process GO:0006544 8 8 0,000 0,02758248 0,06362267 ! ribonucleotide catabolic process GO:0009261 8 8 0,000 0,02758248 0,06354314 ! negative regulation of microtubule depolymerization GO:0007026 8 8 0,000 0,02758248 0,06346381 GO:0031114|regulation of microtubule depolymerization, ! polyamine metabolic process GO:0006595 8 8 0,000 0,02758248 0,06338468 ! Golgi organization GO:0007030 8 8 0,000 0,02758248 0,06330575 ! regulation of stress fiber formation GO:0051492 9 8 0,000 0,02758248 0,06322701 ! fructose metabolic process GO:0006000 8 8 0,000 0,02758248 0,06314847 ! mannose metabolic process GO:0006013 9 8 0,000 0,02758248 0,06307012 ! NAD metabolic process GO:0019674 8 8 0,000 0,02758248 0,06299196 ! negative regulation of mitotic cell cycle GO:0045930 9 8 0,000 0,02758248 0,062914 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 8 8 0,000 0,02758248 0,06283624 ! response to fungus GO:0009620 8 8 0,000 0,02758248 0,06275866 ! stem cell differentiation GO:0048863 8 8 0,000 0,02758248 0,06268128 ! alpha-beta T cell activation GO:0046631 8 8 0,000 0,02758248 0,06260408 ! positive regulation of myeloid leukocyte differentiation GO:0002763 9 8 0,000 0,02758248 0,06252708 ! embryonic digit morphogenesis GO:0042733 8 8 0,000 0,02758248 0,06245026 ! regulation of cytokine production during immune response GO:0002718 8 8 0,000 0,02758248 0,06237364 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 0,02758248 0,0622972 ! regulation of vasodilation GO:0042312 8 8 0,000 0,02758248 0,06222095 ! vasoconstriction GO:0042310 8 8 0,000 0,02758248 0,06214488 ! regulation of T cell mediated immunity GO:0002709 8 8 0,000 0,02758248 0,06206901 ! muscle cell development GO:0055001 8 8 0,000 0,02758248 0,06199331 ! nucleoside triphosphate catabolic process GO:0009143 8 8 0,000 0,02758248 0,0619178 ! regulation of fatty acid metabolic process GO:0019217 8 8 0,000 0,02758248 0,06184248 ! sensory perception of pain GO:0019233 8 8 0,000 0,02758248 0,06176733 ! gastrulation with mouth forming second GO:0001702 8 8 0,000 0,02758248 0,06169237 ! immunoglobulin production during immune response GO:0002381 8 8 0,000 0,02758248 0,06161759 GO:0002208|somatic diversification of immunoglobulins during immune response, GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! mRNA cleavage GO:0006379 8 8 0,000 0,02758248 0,061543 ! chromatin silencing GO:0006342 8 8 0,000 0,02758248 0,06146858 ! tissue regeneration GO:0042246 8 8 0,000 0,02758248 0,06139434 ! salivary gland development GO:0007431 8 8 0,000 0,02758248 0,06132028 ! negative regulation of blood coagulation GO:0030195 9 8 0,000 0,02758248 0,0612464 ! T cell homeostasis GO:0043029 8 8 0,000 0,02758248 0,0611727 ! peptide biosynthetic process GO:0043043 9 8 0,000 0,02758248 0,06109918 ! peptidyl-serine modification GO:0018209 8 8 0,000 0,02758248 0,06102583 ! water homeostasis GO:0030104 8 8 0,000 0,02758248 0,06095266 ! cofactor transport GO:0051181 8 8 0,000 0,02758248 0,06087966 ! regulation of acute inflammatory response GO:0002673 8 8 0,000 0,02758248 0,06080684 ! acid secretion GO:0046717 8 8 0,000 0,02758248 0,06073419 ! C21-steroid hormone biosynthetic process GO:0006700 8 8 0,000 0,02758248 0,06066171 ! protein-chromophore linkage GO:0018298 9 8 0,000 0,02758248 0,06058941 ! regulation of immunoglobulin production GO:0002637 8 8 0,000 0,02758248 0,06051728 ! catecholamine biosynthetic process GO:0042423 8 8 0,000 0,02758248 0,06044532 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 8 8 0,000 0,02758248 0,06037353 ! aromatic compound biosynthetic process GO:0019438 8 8 0,000 0,02758248 0,06030192 ! release of cytochrome c from mitochondria GO:0001836 9 8 0,000 0,02758248 0,06023047 ! regulation of organic acid transport GO:0032890 8 8 0,000 0,02758248 0,06015919 ! positive regulation of calcium ion transport GO:0051928 8 8 0,000 0,02758248 0,06008808 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 8 8 0,000 0,02758248 0,06001714 ! regulation of multi-organism process GO:0043900 8 8 0,000 0,02758248 0,05994636 ! positive regulation of amine transport GO:0051954 8 8 0,000 0,02758248 0,05987575 ! developmental induction GO:0031128 8 8 0,000 0,02758248 0,05980531 GO:0045168|cell-cell signaling involved in cell fate specification, ! peptide hormone secretion GO:0030072 8 8 0,000 0,02758248 0,05973504 ! positive regulation of calcium-mediated signaling GO:0050850 8 8 0,000 0,02758248 0,05966492 ! actin filament polymerization GO:0030041 9 8 0,000 0,02758248 0,05959498 ! cytoplasmic sequestering of protein GO:0051220 8 8 0,000 0,02758248 0,05952519 ! peptide hormone processing GO:0016486 8 8 0,000 0,02758248 0,05945557 ! positive regulation of synaptic transmission GO:0050806 8 8 0,000 0,02758248 0,05938612 ! regulation of steroid biosynthetic process GO:0050810 8 8 0,000 0,02758248 0,05931682 ! response to oxidative stress GO:0006979 76 75 1,000 0,0277211 0,05954545 ! cell morphogenesis involved in differentiation GO:0000904 82 77 1,000 0,02910653 0,06244858 ! positive regulation of protein kinase cascade GO:0010740 79 78 1,000 0,02980959 0,06388264 ! lactation GO:0007595 10 9 0,000 0,03097859 0,06631072 ! embryonic pattern specification GO:0009880 10 9 0,000 0,03097859 0,0662338 ! positive regulation of cell size GO:0045793 9 9 0,000 0,03097859 0,06615705 ! regulation of membrane protein ectodomain proteolysis GO:0051043 9 9 0,000 0,03097859 0,06608048 ! positive regulation of protein complex assembly GO:0031334 9 9 0,000 0,03097859 0,06600408 ! cortical actin cytoskeleton organization GO:0030866 10 9 0,000 0,03097859 0,06592787 ! viral genome replication GO:0019079 9 9 0,000 0,03097859 0,06585183 ! phospholipid catabolic process GO:0009395 9 9 0,000 0,03097859 0,06577596 ! copper ion transport GO:0006825 9 9 0,000 0,03097859 0,06570027 ! lipid phosphorylation GO:0046834 9 9 0,000 0,03097859 0,06562475 ! aminoglycan catabolic process GO:0006026 9 9 0,000 0,03097859 0,06554941 ! Golgi vesicle budding GO:0048194 9 9 0,000 0,03097859 0,06547424 ! regulation of cell-cell adhesion GO:0022407 9 9 0,000 0,03097859 0,06539924 ! RNA polyadenylation GO:0043631 9 9 0,000 0,03097859 0,06532441 GO:0006378|mRNA polyadenylation, ! regulation of postsynaptic membrane potential GO:0060078 9 9 0,000 0,03097859 0,06524975 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 9 9 0,000 0,03097859 0,06517527 ! negative regulation of cytokine biosynthetic process GO:0042036 9 9 0,000 0,03097859 0,06510095 ! phospholipid efflux GO:0033700 9 9 0,000 0,03097859 0,0650268 ! response to alkaloid GO:0043279 10 9 0,000 0,03097859 0,06495283 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 9 9 0,000 0,03097859 0,06487902 ! cytokine biosynthetic process GO:0042089 9 9 0,000 0,03097859 0,06480537 GO:0042107|cytokine metabolic process, ! negative regulation of gene expression, epigenetic GO:0045814 9 9 0,000 0,03097859 0,0647319 ! regulation of interleukin-2 biosynthetic process GO:0045076 9 9 0,000 0,03097859 0,06465859 ! response to ethanol GO:0045471 9 9 0,000 0,03097859 0,06458545 ! pyrimidine ribonucleotide metabolic process GO:0009218 9 9 0,000 0,03097859 0,06451247 ! activation of pro-apoptotic gene products GO:0008633 9 9 0,000 0,03097859 0,06443965 ! methionine metabolic process GO:0006555 9 9 0,000 0,03097859 0,06436701 ! glutamine metabolic process GO:0006541 9 9 0,000 0,03097859 0,06429452 ! cerebral cortex development GO:0021987 9 9 0,000 0,03097859 0,0642222 ! response to osmotic stress GO:0006970 9 9 0,000 0,03097859 0,06415004 ! pigmentation during development GO:0048066 9 9 0,000 0,03097859 0,06407804 ! reverse cholesterol transport GO:0043691 9 9 0,000 0,03097859 0,0640062 ! central nervous system neuron development GO:0021954 10 9 0,000 0,03097859 0,06393453 ! pyrimidine ribonucleoside metabolic process GO:0046131 9 9 0,000 0,03097859 0,06386301 ! nucleobase biosynthetic process GO:0046112 9 9 0,000 0,03097859 0,06379166 ! substrate-bound cell migration GO:0006929 9 9 0,000 0,03097859 0,06372046 ! neurotransmitter metabolic process GO:0042133 11 9 0,000 0,03097859 0,06364942 ! negative regulation of caspase activity GO:0043154 9 9 0,000 0,03097859 0,06357855 ! branching involved in ureteric bud morphogenesis GO:0001658 9 9 0,000 0,03097859 0,06350782 GO:0060675|ureteric bud morphogenesis, ! L-glutamate transport GO:0015813 9 9 0,000 0,03097859 0,06343726 GO:0015800|acidic amino acid transport, ! peptide secretion GO:0002790 9 9 0,000 0,03097859 0,06336685 ! regulation of dephosphorylation GO:0035303 9 9 0,000 0,03097859 0,0632966 ! cotranslational protein targeting to membrane GO:0006613 10 9 0,000 0,03097859 0,0632265 ! positive regulation of alpha-beta T cell differentiation GO:0046638 9 9 0,000 0,03097859 0,06315656 ! ventricular cardiac muscle morphogenesis GO:0055010 9 9 0,000 0,03097859 0,06308678 ! behavioral interaction between organisms GO:0051705 9 9 0,000 0,03097859 0,06301715 ! negative regulation of protein import into nucleus GO:0042308 9 9 0,000 0,03097859 0,06294767 ! positive regulation of protein import into nucleus GO:0042307 9 9 0,000 0,03097859 0,06287834 ! DNA replication initiation GO:0006270 9 9 0,000 0,03097859 0,06280917 ! prostaglandin metabolic process GO:0006693 9 9 0,000 0,03097859 0,06274015 GO:0006692|prostanoid metabolic process, ! T cell differentiation in the thymus GO:0033077 9 9 0,000 0,03097859 0,06267128 ! regulation of cellular pH GO:0030641 9 9 0,000 0,03097859 0,06260256 ! DNA fragmentation involved in apoptosis GO:0006309 9 9 0,000 0,03097859 0,06253399 ! regulation of immunoglobulin mediated immune response GO:0002889 9 9 0,000 0,03097859 0,06246557 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 10 9 0,000 0,03097859 0,0623973 ! positive regulation of cytokine secretion GO:0050715 9 9 0,000 0,03097859 0,06232919 ! negative regulation of inflammatory response GO:0050728 9 9 0,000 0,03097859 0,06226121 ! negative regulation of protein secretion GO:0050709 9 9 0,000 0,03097859 0,06219339 ! positive regulation of transmission of nerve impulse GO:0051971 9 9 0,000 0,03097859 0,06212572 ! collagen catabolic process GO:0030574 9 9 0,000 0,03097859 0,06205819 ! aromatic amino acid family catabolic process GO:0009074 9 9 0,000 0,03097859 0,06199081 ! purine base metabolic process GO:0006144 9 9 0,000 0,03097859 0,06192357 ! gas transport GO:0015669 9 9 0,000 0,03097859 0,06185648 ! cholesterol efflux GO:0033344 9 9 0,000 0,03097859 0,06178954 ! regulation of leukocyte mediated cytotoxicity GO:0001910 9 9 0,000 0,03097859 0,06172274 ! estrogen receptor signaling pathway GO:0030520 9 9 0,000 0,03097859 0,06165608 ! somatic recombination of immunoglobulin gene segments GO:0016447 9 9 0,000 0,03097859 0,06158957 ! regulation of actin filament bundle formation GO:0032231 10 9 0,000 0,03097859 0,0615232 ! defense response to virus GO:0051607 9 9 0,000 0,03097859 0,06145698 ! regulation of calcium-mediated signaling GO:0050848 9 9 0,000 0,03097859 0,0613909 ! actin filament-based movement GO:0030048 9 9 0,000 0,03097859 0,06132496 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 9 9 0,000 0,03097859 0,06125916 ! cellular amino acid derivative metabolic process GO:0006575 87 84 1,000 0,03416949 0,06749665 ! protein import into nucleus, docking GO:0000059 10 10 0,000 0,03436332 0,06780685 ! regulation of protein ubiquitination GO:0031396 10 10 0,000 0,03436332 0,06773433 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 10 10 0,000 0,03436332 0,06766197 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 10 10 0,000 0,03436332 0,06758975 ! ER-associated protein catabolic process GO:0030433 10 10 0,000 0,03436332 0,0675177 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of cell killing GO:0031341 10 10 0,000 0,03436332 0,06744579 ! neuron maturation GO:0042551 10 10 0,000 0,03436332 0,06737404 ! pteridine and derivative metabolic process GO:0042558 10 10 0,000 0,03436332 0,06730244 ! cortical cytoskeleton organization GO:0030865 11 10 0,000 0,03436332 0,067231 ! regulation of lipid biosynthetic process GO:0046890 10 10 0,000 0,03436332 0,0671597 ! reciprocal meiotic recombination GO:0007131 10 10 0,000 0,03436332 0,06708856 ! hormone secretion GO:0046879 10 10 0,000 0,03436332 0,06701757 ! glucosamine metabolic process GO:0006041 10 10 0,000 0,03436332 0,06694672 GO:0006044|N-acetylglucosamine metabolic process, ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 10 10 0,000 0,03436332 0,06687603 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! negative regulation of nucleocytoplasmic transport GO:0046823 10 10 0,000 0,03436332 0,06680549 ! inositol metabolic process GO:0006020 10 10 0,000 0,03436332 0,06673509 ! cAMP metabolic process GO:0046058 10 10 0,000 0,03436332 0,06666484 ! vesicle targeting, to, from or within Golgi GO:0048199 10 10 0,000 0,03436332 0,06659474 ! transcription from RNA polymerase III promoter GO:0006383 10 10 0,000 0,03436332 0,06652479 ! forelimb morphogenesis GO:0035136 10 10 0,000 0,03436332 0,06645498 ! glial cell development GO:0021782 10 10 0,000 0,03436332 0,06638532 ! phototransduction GO:0007602 11 10 0,000 0,03436332 0,06631581 ! auditory receptor cell differentiation GO:0042491 10 10 0,000 0,03436332 0,06624644 ! apoptotic mitochondrial changes GO:0008637 11 10 0,000 0,03436332 0,06617722 ! fat cell differentiation GO:0045444 10 10 0,000 0,03436332 0,06610814 ! myoblast differentiation GO:0045445 10 10 0,000 0,03436332 0,06603921 ! centrosome cycle GO:0007098 10 10 0,000 0,03436332 0,06597042 ! inactivation of MAPK activity GO:0000188 10 10 0,000 0,03436332 0,06590177 ! positive regulation of proteolysis GO:0045862 10 10 0,000 0,03436332 0,06583326 ! response to carbohydrate stimulus GO:0009743 10 10 0,000 0,03436332 0,0657649 ! regulation of survival gene product expression GO:0045884 10 10 0,000 0,03436332 0,06569668 ! induction of apoptosis via death domain receptors GO:0008625 10 10 0,000 0,03436332 0,0656286 ! epidermis morphogenesis GO:0048730 10 10 0,000 0,03436332 0,06556066 ! protein polyubiquitination GO:0000209 10 10 0,000 0,03436332 0,06549286 ! glutamate metabolic process GO:0006536 11 10 0,000 0,03436332 0,06542521 ! plasma membrane organization GO:0007009 10 10 0,000 0,03436332 0,06535769 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 10 10 0,000 0,03436332 0,06529031 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! lysosomal transport GO:0007041 10 10 0,000 0,03436332 0,06522307 ! cellular response to unfolded protein GO:0034620 10 10 0,000 0,03436332 0,06515597 GO:0030968|endoplasmic reticulum unfolded protein response, ! central nervous system neuron differentiation GO:0021953 11 10 0,000 0,03436332 0,065089 ! purine ribonucleoside metabolic process GO:0046128 10 10 0,000 0,03436332 0,06502218 GO:0042278|purine nucleoside metabolic process, ! vesicle coating GO:0006901 10 10 0,000 0,03436332 0,06495549 ! exocrine system development GO:0035272 10 10 0,000 0,03436332 0,06488893 ! cell structure disassembly during apoptosis GO:0006921 10 10 0,000 0,03436332 0,06482252 ! neuromuscular junction development GO:0007528 10 10 0,000 0,03436332 0,06475624 ! embryo implantation GO:0007566 11 10 0,000 0,03436332 0,06469009 ! regulation of protein binding GO:0043393 11 10 0,000 0,03436332 0,06462408 ! protein targeting to peroxisome GO:0006625 10 10 0,000 0,03436332 0,06455821 ! protein targeting to mitochondrion GO:0006626 10 10 0,000 0,03436332 0,06449246 GO:0070585|protein localization in mitochondrion, ! regulation of alpha-beta T cell differentiation GO:0046637 10 10 0,000 0,03436332 0,06442686 ! intermediate filament cytoskeleton organization GO:0045104 10 10 0,000 0,03436332 0,06436138 ! protein export from nucleus GO:0006611 10 10 0,000 0,03436332 0,06429604 ! negative regulation of immune response GO:0050777 10 10 0,000 0,03436332 0,06423083 ! cytolysis GO:0019835 10 10 0,000 0,03436332 0,06416575 ! positive regulation of biomineral formation GO:0070169 10 10 0,000 0,03436332 0,06410081 GO:0030501|positive regulation of bone mineralization, ! mismatch repair GO:0006298 10 10 0,000 0,03436332 0,064036 ! regulation of B cell differentiation GO:0045577 10 10 0,000 0,03436332 0,06397131 ! histone deacetylation GO:0016575 10 10 0,000 0,03436332 0,06390676 ! mRNA splice site selection GO:0006376 11 10 0,000 0,03436332 0,06384234 ! synaptic vesicle transport GO:0048489 11 10 0,000 0,03436332 0,06377805 ! gland morphogenesis GO:0022612 10 10 0,000 0,03436332 0,06371388 ! positive regulation of neurological system process GO:0031646 10 10 0,000 0,03436332 0,06364985 ! sphingolipid biosynthetic process GO:0030148 10 10 0,000 0,03436332 0,06358594 GO:0046467|membrane lipid biosynthetic process, ! sphingolipid catabolic process GO:0030149 10 10 0,000 0,03436332 0,06352217 GO:0046466|membrane lipid catabolic process, ! nerve-nerve synaptic transmission GO:0007270 10 10 0,000 0,03436332 0,06345852 ! regulation of epidermis development GO:0045682 10 10 0,000 0,03436332 0,063395 ! folic acid and derivative metabolic process GO:0006760 10 10 0,000 0,03436332 0,0633316 ! negative regulation of neuron differentiation GO:0045665 10 10 0,000 0,03436332 0,06326833 ! aspartate family amino acid biosynthetic process GO:0009067 10 10 0,000 0,03436332 0,06320519 ! regulation of BMP signaling pathway GO:0030510 10 10 0,000 0,03436332 0,06314217 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 10 10 0,000 0,03436332 0,06307928 ! lymphocyte homeostasis GO:0002260 10 10 0,000 0,03436332 0,06301652 ! nerve development GO:0021675 10 10 0,000 0,03436332 0,06295388 ! gut development GO:0048565 10 10 0,000 0,03436332 0,06289136 ! embryonic organ morphogenesis GO:0048562 10 10 0,000 0,03436332 0,06282897 ! positive regulation of neuron apoptosis GO:0043525 10 10 0,000 0,03436332 0,0627667 ! mRNA 3'-end processing GO:0031124 10 10 0,000 0,03436332 0,06270455 ! antigen receptor-mediated signaling pathway GO:0050851 10 10 0,000 0,03436332 0,06264253 ! negative regulation of coagulation GO:0050819 11 10 0,000 0,03436332 0,06258063 ! protein stabilization GO:0050821 10 10 0,000 0,03436332 0,06251885 ! positive regulation of cell differentiation GO:0045597 87 85 1,000 0,03491926 0,06346765 ! positive regulation of response to stimulus GO:0048584 86 85 1,000 0,03491926 0,06340512 ! hexose metabolic process GO:0019318 87 86 1,000 0,0356755 0,06471451 ! protein secretion GO:0009306 11 11 0,000 0,03773672 0,06838622 ! oligosaccharide metabolic process GO:0009311 11 11 0,000 0,03773672 0,06831904 ! negative regulation of defense response GO:0031348 11 11 0,000 0,03773672 0,06825199 ! G1 phase of mitotic cell cycle GO:0000080 12 11 0,000 0,03773672 0,06818508 ! determination of bilateral symmetry GO:0009855 11 11 0,000 0,03773672 0,0681183 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! positive regulation of hormone secretion GO:0046887 11 11 0,000 0,03773672 0,06805165 ! phosphatidylinositol metabolic process GO:0046488 11 11 0,000 0,03773672 0,06798512 ! skin development GO:0043588 11 11 0,000 0,03773672 0,06791873 ! cellular component assembly involved in morphogenesis GO:0010927 11 11 0,000 0,03773672 0,06785247 ! signal complex assembly GO:0007172 11 11 0,000 0,03773672 0,06778634 ! microtubule-based transport GO:0010970 11 11 0,000 0,03773672 0,06772033 ! endothelial cell migration GO:0043542 11 11 0,000 0,03773672 0,06765446 ! peroxisomal transport GO:0043574 11 11 0,000 0,03773672 0,06758871 ! protein amino acid methylation GO:0006479 11 11 0,000 0,03773672 0,06752309 GO:0008213|protein amino acid alkylation, ! positive regulation of nucleocytoplasmic transport GO:0046824 11 11 0,000 0,03773672 0,0674576 GO:0032388|positive regulation of intracellular transport, ! heart contraction GO:0060047 11 11 0,000 0,03773672 0,06739223 GO:0003015|heart process, ! detection of light stimulus involved in sensory perception GO:0050962 12 11 0,000 0,03773672 0,06732699 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 11 11 0,000 0,03773672 0,06726188 ! T cell proliferation GO:0042098 11 11 0,000 0,03773672 0,06719689 ! regulation of transmembrane transporter activity GO:0022898 11 11 0,000 0,03773672 0,06713203 GO:0032412|regulation of ion transmembrane transporter activity, GO:0032409|regulation of transporter activity, ! negative regulation of endothelial cell proliferation GO:0001937 11 11 0,000 0,03773672 0,06706729 ! regulation of viral genome replication GO:0045069 11 11 0,000 0,03773672 0,06700268 ! spinal cord development GO:0021510 11 11 0,000 0,03773672 0,06693819 ! activation of MAPKK activity GO:0000186 12 11 0,000 0,03773672 0,06687383 ! smooth muscle contraction GO:0006939 11 11 0,000 0,03773672 0,06680959 ! cellular response to starvation GO:0009267 11 11 0,000 0,03773672 0,06674547 ! cellular macromolecular complex disassembly GO:0034623 12 11 0,000 0,03773672 0,06668148 ! digestive system process GO:0022600 11 11 0,000 0,03773672 0,06661761 ! mitotic spindle organization GO:0007052 11 11 0,000 0,03773672 0,06655386 ! fucose metabolic process GO:0006004 11 11 0,000 0,03773672 0,06649023 ! membrane budding GO:0006900 11 11 0,000 0,03773672 0,06642673 ! apoptotic nuclear changes GO:0030262 11 11 0,000 0,03773672 0,06636334 ! monoamine transport GO:0015844 11 11 0,000 0,03773672 0,06630008 ! regulation of cellular ketone metabolic process GO:0010565 11 11 0,000 0,03773672 0,06623694 ! response to lipopolysaccharide GO:0032496 11 11 0,000 0,03773672 0,06617391 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 11 11 0,000 0,03773672 0,06611101 ! body fluid secretion GO:0007589 11 11 0,000 0,03773672 0,06604823 ! G1/S transition checkpoint GO:0031575 12 11 0,000 0,03773672 0,06598556 ! positive regulation of alpha-beta T cell activation GO:0046635 11 11 0,000 0,03773672 0,06592302 ! intermediate filament-based process GO:0045103 11 11 0,000 0,03773672 0,06586059 ! cardiac muscle tissue morphogenesis GO:0055008 11 11 0,000 0,03773672 0,06579828 GO:0060415|muscle tissue morphogenesis, ! membrane depolarization GO:0051899 11 11 0,000 0,03773672 0,06573609 ! regulation of interleukin-2 production GO:0032663 11 11 0,000 0,03773672 0,06567402 ! regulation of ARF GTPase activity GO:0032312 11 11 0,000 0,03773672 0,06561206 ! oogenesis GO:0048477 11 11 0,000 0,03773672 0,06555022 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 11 11 0,000 0,03773672 0,0654885 ! vitamin transport GO:0051180 11 11 0,000 0,03773672 0,06542689 ! vitamin A metabolic process GO:0006776 11 11 0,000 0,03773672 0,0653654 ! hindbrain development GO:0030902 11 11 0,000 0,03773672 0,06530402 ! steroid catabolic process GO:0006706 11 11 0,000 0,03773672 0,06524276 ! endocrine process GO:0050886 11 11 0,000 0,03773672 0,06518161 GO:0001990|regulation of systemic arterial blood pressure by hormone, ! aromatic amino acid family metabolic process GO:0009072 11 11 0,000 0,03773672 0,06512058 ! proximal/distal pattern formation GO:0009954 11 11 0,000 0,03773672 0,06505967 ! somatic diversification of immunoglobulins GO:0016445 11 11 0,000 0,03773672 0,06499886 ! RNA 3'-end processing GO:0031123 11 11 0,000 0,03773672 0,06493817 ! negative regulation of lymphocyte activation GO:0051250 11 11 0,000 0,03773672 0,0648776 ! cellular di-, tri-valent inorganic cation homeostasis GO:0030005 89 89 1,000 0,03798252 0,06523932 ! regulation of Ras protein signal transduction GO:0046578 90 90 1,000 0,03876414 0,06651984 ! brain development GO:0007420 91 90 1,000 0,03876414 0,06645796 ! negative regulation of cell cycle GO:0045786 92 91 1,000 0,03955198 0,06774563 ! di-, tri-valent inorganic cation homeostasis GO:0055066 91 91 1,000 0,03955198 0,06768272 ! DNA replication GO:0006260 91 91 1,000 0,03955198 0,06761994 ! fatty acid metabolic process GO:0006631 93 92 1,000 0,04034599 0,06891349 ! energy derivation by oxidation of organic compounds GO:0015980 94 92 1,000 0,04034599 0,06884968 ! positive regulation of immune system process GO:0002684 92 92 1,000 0,04034599 0,06878599 ! positive regulation of protein catabolic process GO:0045732 12 12 0,000 0,04109883 0,07000476 ! translational initiation GO:0006413 12 12 0,000 0,04109883 0,06994012 ! initiation of viral infection GO:0019059 12 12 0,000 0,04109883 0,0698756 ! DNA catabolic process, endonucleolytic GO:0000737 12 12 0,000 0,04109883 0,0698112 ! iron ion transport GO:0006826 13 12 0,000 0,04109883 0,06974691 ! phosphatidylcholine metabolic process GO:0046470 12 12 0,000 0,04109883 0,06968275 ! amino sugar metabolic process GO:0006040 12 12 0,000 0,04109883 0,0696187 ! post-Golgi vesicle-mediated transport GO:0006892 12 12 0,000 0,04109883 0,06955477 ! protein amino acid ADP-ribosylation GO:0006471 12 12 0,000 0,04109883 0,06949096 ! heterophilic cell adhesion GO:0007157 12 12 0,000 0,04109883 0,06942727 ! hindlimb morphogenesis GO:0035137 12 12 0,000 0,04109883 0,06936369 ! xenobiotic metabolic process GO:0006805 12 12 0,000 0,04109883 0,06930023 ! glutamate signaling pathway GO:0007215 12 12 0,000 0,04109883 0,06923688 ! C21-steroid hormone metabolic process GO:0008207 13 12 0,000 0,04109883 0,06917365 ! regulation of muscle cell differentiation GO:0051147 13 12 0,000 0,04109883 0,06911054 ! cellular response to hydrogen peroxide GO:0070301 12 12 0,000 0,04109883 0,06904754 GO:0042744|hydrogen peroxide catabolic process, ! negative regulation of peptidase activity GO:0010466 12 12 0,000 0,04109883 0,06898465 ! actomyosin structure organization GO:0031032 12 12 0,000 0,04109883 0,06892188 ! microtubule organizing center organization GO:0031023 12 12 0,000 0,04109883 0,06885922 GO:0051297|centrosome organization, ! positive regulation of endocytosis GO:0045807 12 12 0,000 0,04109883 0,06879668 ! retinoid metabolic process GO:0001523 12 12 0,000 0,04109883 0,06873425 GO:0016101|diterpenoid metabolic process, ! mitotic chromosome condensation GO:0007076 12 12 0,000 0,04109883 0,06867194 ! positive regulation of innate immune response GO:0045089 12 12 0,000 0,04109883 0,06860973 ! GPI anchor biosynthetic process GO:0006506 12 12 0,000 0,04109883 0,06854764 GO:0006505|GPI anchor metabolic process, ! glycoprotein catabolic process GO:0006516 13 12 0,000 0,04109883 0,06848567 ! acute-phase response GO:0006953 12 12 0,000 0,04109883 0,0684238 ! deoxyribonucleotide catabolic process GO:0009264 12 12 0,000 0,04109883 0,06836205 ! vacuolar transport GO:0007034 12 12 0,000 0,04109883 0,0683004 ! polysaccharide catabolic process GO:0000272 12 12 0,000 0,04109883 0,06823887 ! vesicle docking during exocytosis GO:0006904 12 12 0,000 0,04109883 0,06817745 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 12 12 0,000 0,04109883 0,06811614 ! barbed-end actin filament capping GO:0051016 12 12 0,000 0,04109883 0,06805494 GO:0051693|actin filament capping, ! male gonad development GO:0008584 12 12 0,000 0,04109883 0,06799385 ! regulation of insulin secretion GO:0050796 12 12 0,000 0,04109883 0,06793287 ! regulation of alpha-beta T cell activation GO:0046634 12 12 0,000 0,04109883 0,067872 ! renal system process GO:0003014 12 12 0,000 0,04109883 0,06781123 ! regulation of tumor necrosis factor production GO:0032680 12 12 0,000 0,04109883 0,06775058 ! regulation of steroid metabolic process GO:0019218 12 12 0,000 0,04109883 0,06769003 ! regulation of interleukin-6 production GO:0032675 12 12 0,000 0,04109883 0,0676296 ! pallium development GO:0021543 13 12 0,000 0,04109883 0,06756927 ! cell fate determination GO:0001709 12 12 0,000 0,04109883 0,06750904 ! G1 phase GO:0051318 13 12 0,000 0,04109883 0,06744893 ! regulation of response to biotic stimulus GO:0002831 12 12 0,000 0,04109883 0,06738892 ! positive regulation of adaptive immune response GO:0002821 12 12 0,000 0,04109883 0,06732902 ! detection of light stimulus GO:0009583 13 12 0,000 0,04109883 0,06726922 ! synaptogenesis GO:0007416 12 12 0,000 0,04109883 0,06720954 ! fat-soluble vitamin metabolic process GO:0006775 12 12 0,000 0,04109883 0,06714995 ! hormone transport GO:0009914 12 12 0,000 0,04109883 0,06709048 ! neurotransmitter secretion GO:0007269 14 12 0,000 0,04109883 0,0670311 ! heme biosynthetic process GO:0006783 12 12 0,000 0,04109883 0,06697184 ! spermatid differentiation GO:0048515 13 12 0,000 0,04109883 0,06691267 GO:0007286|spermatid development, ! aromatic compound catabolic process GO:0019439 13 12 0,000 0,04109883 0,06685362 ! pyrimidine nucleotide biosynthetic process GO:0006221 12 12 0,000 0,04109883 0,06679466 ! neural tube closure GO:0001843 13 12 0,000 0,04109883 0,06673581 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! negative regulation of translation GO:0017148 12 12 0,000 0,04109883 0,06667707 ! regulation of microtubule polymerization or depolymerization GO:0031110 12 12 0,000 0,04109883 0,06661842 ! cellular monovalent inorganic cation homeostasis GO:0030004 12 12 0,000 0,04109883 0,06655988 ! pattern specification process GO:0007389 96 94 1,000 0,04195233 0,06788248 ! epidermis development GO:0008544 94 94 1,000 0,04195233 0,06782293 ! cofactor metabolic process GO:0051186 95 94 1,000 0,04195233 0,06776349 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 13 13 0,000 0,04444968 0,07173447 GO:0016444|somatic cell DNA recombination, ! negative regulation of actin filament polymerization GO:0030837 13 13 0,000 0,04444968 0,07167171 ! phenol metabolic process GO:0018958 13 13 0,000 0,04444968 0,07160906 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, GO:0009712|catechol metabolic process, ! G2/M transition of mitotic cell cycle GO:0000086 13 13 0,000 0,04444968 0,07154652 ! gluconeogenesis GO:0006094 13 13 0,000 0,04444968 0,07148408 ! negative regulation of hormone secretion GO:0046888 13 13 0,000 0,04444968 0,07142176 ! 2'-deoxyribonucleotide metabolic process GO:0009394 13 13 0,000 0,04444968 0,07135955 GO:0019692|deoxyribose phosphate metabolic process, ! intra-Golgi vesicle-mediated transport GO:0006891 13 13 0,000 0,04444968 0,07129744 ! glycosaminoglycan biosynthetic process GO:0006024 13 13 0,000 0,04444968 0,07123544 ! regeneration GO:0031099 13 13 0,000 0,04444968 0,07117355 ! keratinization GO:0031424 13 13 0,000 0,04444968 0,07111177 ! post-embryonic development GO:0009791 14 13 0,000 0,04444968 0,0710501 ! negative regulation of protein modification process GO:0031400 13 13 0,000 0,04444968 0,07098853 ! patterning of blood vessels GO:0001569 13 13 0,000 0,04444968 0,07092707 ! regulation of DNA recombination GO:0000018 13 13 0,000 0,04444968 0,07086571 ! regulation of innate immune response GO:0045088 13 13 0,000 0,04444968 0,07080446 ! mitochondrial membrane organization GO:0007006 13 13 0,000 0,04444968 0,07074332 ! negative regulation of DNA replication GO:0008156 13 13 0,000 0,04444968 0,07068228 ! response to corticosteroid stimulus GO:0031960 13 13 0,000 0,04444968 0,07062135 GO:0051384|response to glucocorticoid stimulus, ! multicellular organismal catabolic process GO:0044243 13 13 0,000 0,04444968 0,07056052 ! autophagy GO:0006914 13 13 0,000 0,04444968 0,07049979 ! receptor metabolic process GO:0043112 14 13 0,000 0,04444968 0,07043918 ! negative regulation of protein catabolic process GO:0042177 13 13 0,000 0,04444968 0,07037866 ! ureteric bud development GO:0001657 13 13 0,000 0,04444968 0,07031825 ! cell aging GO:0007569 13 13 0,000 0,04444968 0,07025794 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 13 13 0,000 0,04444968 0,07019774 ! response to endoplasmic reticulum stress GO:0034976 13 13 0,000 0,04444968 0,07013764 ! negative regulation of protein kinase cascade GO:0010741 13 13 0,000 0,04444968 0,07007764 ! purine nucleoside monophosphate metabolic process GO:0009126 13 13 0,000 0,04444968 0,07001774 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of peptide secretion GO:0002791 13 13 0,000 0,04444968 0,06995795 ! regulation of viral reproduction GO:0050792 13 13 0,000 0,04444968 0,06989826 ! nucleobase metabolic process GO:0009112 13 13 0,000 0,04444968 0,06983867 ! regulation of axonogenesis GO:0050770 14 13 0,000 0,04444968 0,06977918 ! positive regulation of neurogenesis GO:0050769 13 13 0,000 0,04444968 0,0697198 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 14 13 0,000 0,04444968 0,06966051 ! nucleotide-excision repair, DNA gap filling GO:0006297 13 13 0,000 0,04444968 0,06960133 ! vasodilation GO:0042311 14 13 0,000 0,04444968 0,06954224 ! positive regulation of leukocyte mediated immunity GO:0002705 13 13 0,000 0,04444968 0,06948326 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 13 13 0,000 0,04444968 0,06942437 ! glycosphingolipid metabolic process GO:0006687 13 13 0,000 0,04444968 0,06936559 GO:0006664|glycolipid metabolic process, ! neutrophil chemotaxis GO:0030593 14 13 0,000 0,04444968 0,0693069 ! long-chain fatty acid transport GO:0015909 13 13 0,000 0,04444968 0,06924832 ! immunoglobulin production GO:0002377 13 13 0,000 0,04444968 0,06918983 GO:0002440|production of molecular mediator of immune response, ! negative regulation of Wnt receptor signaling pathway GO:0030178 13 13 0,000 0,04444968 0,06913144 ! negative regulation of intracellular transport GO:0032387 13 13 0,000 0,04444968 0,06907315 ! negative regulation of leukocyte activation GO:0002695 13 13 0,000 0,04444968 0,06901496 ! negative regulation of myeloid cell differentiation GO:0045638 13 13 0,000 0,04444968 0,06895687 ! response to cytokine stimulus GO:0034097 13 13 0,000 0,04444968 0,06889887 ! activation of JUN kinase activity GO:0007257 13 13 0,000 0,04444968 0,06884098 ! terpenoid metabolic process GO:0006721 13 13 0,000 0,04444968 0,06878317 ! alkene biosynthetic process GO:0043450 13 13 0,000 0,04444968 0,06872547 GO:0019370|leukotriene biosynthetic process, ! purine nucleotide catabolic process GO:0006195 13 13 0,000 0,04444968 0,06866786 ! porphyrin biosynthetic process GO:0006779 13 13 0,000 0,04444968 0,06861035 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of cytokine production GO:0001818 13 13 0,000 0,04444968 0,06855294 ! camera-type eye morphogenesis GO:0048593 13 13 0,000 0,04444968 0,06849562 ! pyrimidine nucleoside metabolic process GO:0006213 13 13 0,000 0,04444968 0,0684384 ! blastocyst development GO:0001824 13 13 0,000 0,04444968 0,06838127 ! telomere organization GO:0032200 13 13 0,000 0,04444968 0,06832424 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 13 13 0,000 0,04444968 0,0682673 ! regulation of amine transport GO:0051952 13 13 0,000 0,04444968 0,06821046 ! tissue homeostasis GO:0001894 13 13 0,000 0,04444968 0,06815371 GO:0048871|multicellular organismal homeostasis, ! inner ear receptor cell differentiation GO:0060113 13 13 0,000 0,04444968 0,06809706 ! endocytosis GO:0006897 99 98 1,000 0,04523695 0,0692456 GO:0010324|membrane invagination, ! posttranscriptional regulation of gene expression GO:0010608 98 98 1,000 0,04523695 0,06918814 ! glycoprotein metabolic process GO:0009100 99 98 1,000 0,04523695 0,06913077 ! blood circulation GO:0008015 99 98 1,000 0,04523695 0,06907349 GO:0003013|circulatory system process, ! ectoderm development GO:0007398 99 99 1,000 0,04607282 0,07029156 ! muscle organ development GO:0007517 102 100 1,000 0,04691448 0,07151644 ! negative regulation of transcription from RNA polymerase II promoter GO:0000122 103 100 1,000 0,04691448 0,07145734 ! neuron fate commitment GO:0048663 14 14 0,000 0,04778931 0,07272972 ! sulfur amino acid metabolic process GO:0000096 14 14 0,000 0,04778931 0,07266971 ! regulation of interferon-gamma production GO:0032649 14 14 0,000 0,04778931 0,0726098 ! pyruvate metabolic process GO:0006090 14 14 0,000 0,04778931 0,07254999 ! cellular aldehyde metabolic process GO:0006081 14 14 0,000 0,04778931 0,07249028 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 14 14 0,000 0,04778931 0,07243067 ! regulation of neuron projection development GO:0010975 15 14 0,000 0,04778931 0,07237115 ! protein amino acid deacetylation GO:0006476 14 14 0,000 0,04778931 0,07231173 ! aminoglycan biosynthetic process GO:0006023 14 14 0,000 0,04778931 0,07225241 ! vesicle docking GO:0048278 14 14 0,000 0,04778931 0,07219319 ! superoxide metabolic process GO:0006801 15 14 0,000 0,04778931 0,07213406 ! macromolecular complex disassembly GO:0032984 15 14 0,000 0,04778931 0,07207503 ! mechanoreceptor differentiation GO:0042490 14 14 0,000 0,04778931 0,0720161 ! isoprenoid biosynthetic process GO:0008299 14 14 0,000 0,04778931 0,07195726 ! hair cycle GO:0042633 14 14 0,000 0,04778931 0,07189852 GO:0022404|molting cycle process, GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042303|molting cycle, ! negative regulation of epithelial cell proliferation GO:0050680 14 14 0,000 0,04778931 0,07183988 ! immune response-activating cell surface receptor signaling pathway GO:0002429 14 14 0,000 0,04778931 0,07178133 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! multicellular organismal response to stress GO:0033555 14 14 0,000 0,04778931 0,07172287 ! lysosome organization GO:0007040 14 14 0,000 0,04778931 0,07166452 ! actin polymerization or depolymerization GO:0008154 15 14 0,000 0,04778931 0,07160625 ! D-ribose metabolic process GO:0006014 14 14 0,000 0,04778931 0,07154808 ! negative regulation of phosphorus metabolic process GO:0010563 14 14 0,000 0,04778931 0,07149001 GO:0045936|negative regulation of phosphate metabolic process, ! peptide transport GO:0015833 14 14 0,000 0,04778931 0,07143203 ! primary neural tube formation GO:0014020 15 14 0,000 0,04778931 0,07137414 ! peptide cross-linking GO:0018149 14 14 0,000 0,04778931 0,07131635 ! vitamin biosynthetic process GO:0009110 14 14 0,000 0,04778931 0,07125865 ! base-excision repair GO:0006284 14 14 0,000 0,04778931 0,07120104 ! response to organic cyclic substance GO:0014070 15 14 0,000 0,04778931 0,07114353 ! leukotriene metabolic process GO:0006691 14 14 0,000 0,04778931 0,07108611 ! regulation of vasoconstriction GO:0019229 14 14 0,000 0,04778931 0,07102878 ! formation of primary germ layer GO:0001704 14 14 0,000 0,04778931 0,07097155 GO:0001707|mesoderm formation, ! DNA modification GO:0006304 14 14 0,000 0,04778931 0,0709144 ! collagen fibril organization GO:0030199 14 14 0,000 0,04778931 0,07085735 ! proteoglycan biosynthetic process GO:0030166 14 14 0,000 0,04778931 0,07080039 ! regulation of blood coagulation GO:0030193 15 14 0,000 0,04778931 0,07074353 ! positive regulation of inflammatory response GO:0050729 14 14 0,000 0,04778931 0,07068675 ! group transfer coenzyme metabolic process GO:0006752 14 14 0,000 0,04778931 0,07063006 ! positive regulation of osteoblast differentiation GO:0045669 14 14 0,000 0,04778931 0,07057347 ! neuromuscular process controlling balance GO:0050885 14 14 0,000 0,04778931 0,07051697 ! aspartate family amino acid metabolic process GO:0009066 14 14 0,000 0,04778931 0,07046055 ! response to molecule of bacterial origin GO:0002237 14 14 0,000 0,04778931 0,07040423 ! negative regulation of protein polymerization GO:0032272 14 14 0,000 0,04778931 0,070348 ! protein import into nucleus, translocation GO:0000060 15 15 0,000 0,05111774 0,07518755 ! positive regulation of fibroblast proliferation GO:0048146 15 15 0,000 0,05111774 0,07512759 ! negative regulation of actin filament depolymerization GO:0030835 15 15 0,000 0,05111774 0,07506773 ! positive regulation of ossification GO:0045778 15 15 0,000 0,05111774 0,07500796 GO:0046852|positive regulation of bone remodeling, GO:0034105|positive regulation of tissue remodeling, ! protein amino acid O-linked glycosylation GO:0006493 15 15 0,000 0,05111774 0,07494829 ! cellular polysaccharide biosynthetic process GO:0033692 15 15 0,000 0,05111774 0,07488871 ! proteoglycan metabolic process GO:0006029 15 15 0,000 0,05111774 0,07482923 ! regulation of transcription factor import into nucleus GO:0042990 15 15 0,000 0,05111774 0,07476984 ! striated muscle cell differentiation GO:0051146 16 15 0,000 0,05111774 0,07471055 ! odontogenesis of dentine-containing tooth GO:0042475 15 15 0,000 0,05111774 0,07465135 ! detection of stimulus involved in sensory perception GO:0050906 16 15 0,000 0,05111774 0,07459224 ! ovarian follicle development GO:0001541 15 15 0,000 0,05111774 0,07453323 ! antigen processing and presentation of peptide antigen GO:0048002 15 15 0,000 0,05111774 0,07447431 ! regulation of smooth muscle contraction GO:0006940 15 15 0,000 0,05111774 0,07441548 ! deoxyribonucleotide metabolic process GO:0009262 15 15 0,000 0,05111774 0,07435675 ! complement activation, classical pathway GO:0006958 15 15 0,000 0,05111774 0,07429811 ! ER-nuclear signaling pathway GO:0006984 15 15 0,000 0,05111774 0,07423956 ! heme metabolic process GO:0042168 15 15 0,000 0,05111774 0,0741811 ! mesoderm morphogenesis GO:0048332 15 15 0,000 0,05111774 0,07412274 ! chromosome condensation GO:0030261 15 15 0,000 0,05111774 0,07406447 ! response to starvation GO:0042594 15 15 0,000 0,05111774 0,07400629 ! response to ionizing radiation GO:0010212 16 15 0,000 0,05111774 0,0739482 ! response to mechanical stimulus GO:0009612 15 15 0,000 0,05111774 0,0738902 ! hydrogen peroxide metabolic process GO:0042743 15 15 0,000 0,05111774 0,07383229 ! regulation of biomineral formation GO:0070167 15 15 0,000 0,05111774 0,07377447 GO:0030500|regulation of bone mineralization, ! regulation of production of molecular mediator of immune response GO:0002700 15 15 0,000 0,05111774 0,07371675 ! cyclic nucleotide biosynthetic process GO:0009190 15 15 0,000 0,05111774 0,07365911 ! cholesterol biosynthetic process GO:0006695 15 15 0,000 0,05111774 0,07360156 ! phospholipid transport GO:0015914 15 15 0,000 0,05111774 0,07354411 ! leukocyte homeostasis GO:0001776 15 15 0,000 0,05111774 0,07348674 ! regulation of cytokine secretion GO:0050707 15 15 0,000 0,05111774 0,07342946 ! glutathione metabolic process GO:0006749 16 15 0,000 0,05111774 0,07337228 ! nicotinamide metabolic process GO:0006769 15 15 0,000 0,05111774 0,07331518 GO:0046496|nicotinamide nucleotide metabolic process, ! positive regulation of B cell activation GO:0050871 15 15 0,000 0,05111774 0,07325817 ! cellular alkene metabolic process GO:0043449 15 15 0,000 0,05111774 0,07320124 ! negative regulation of transcription factor activity GO:0043433 16 15 0,000 0,05111774 0,07314441 GO:0090048|negative regulation of transcription regulator activity, ! somatic diversification of immune receptors GO:0002200 15 15 0,000 0,05111774 0,07308767 ! negative regulation of cell activation GO:0050866 15 15 0,000 0,05111774 0,07303101 ! protein homooligomerization GO:0051260 15 15 0,000 0,05111774 0,07297444 ! positive regulation of immune effector process GO:0002699 15 15 0,000 0,05111774 0,07291796 ! alkaloid metabolic process GO:0009820 16 16 0,000 0,05443503 0,07758992 ! regulation of synaptic plasticity GO:0048167 16 16 0,000 0,05443503 0,07752995 ! spliceosomal snRNP biogenesis GO:0000387 16 16 0,000 0,05443503 0,07747009 ! learning GO:0007612 16 16 0,000 0,05443503 0,07741031 ! circadian rhythm GO:0007623 16 16 0,000 0,05443503 0,07735063 ! inner ear morphogenesis GO:0042472 16 16 0,000 0,05443503 0,07729103 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 16 16 0,000 0,05443503 0,07723153 ! vacuole organization GO:0007033 16 16 0,000 0,05443503 0,07717212 ! cellular response to reactive oxygen species GO:0034614 16 16 0,000 0,05443503 0,07711281 ! positive regulation of cytoskeleton organization GO:0051495 16 16 0,000 0,05443503 0,07705358 ! vesicle targeting GO:0006903 17 16 0,000 0,05443503 0,07699444 ! fatty acid beta-oxidation GO:0006635 16 16 0,000 0,05443503 0,0769354 ! triglyceride metabolic process GO:0006641 16 16 0,000 0,05443503 0,07687645 ! positive regulation of cell development GO:0010720 16 16 0,000 0,05443503 0,07681758 ! regulation of myeloid leukocyte differentiation GO:0002761 17 16 0,000 0,05443503 0,07675881 ! lymphocyte proliferation GO:0046651 16 16 0,000 0,05443503 0,07670012 ! regulation of systemic arterial blood pressure GO:0003073 17 16 0,000 0,05443503 0,07664153 ! cell fate specification GO:0001708 16 16 0,000 0,05443503 0,07658302 ! pentose metabolic process GO:0019321 16 16 0,000 0,05443503 0,07652461 ! fatty acid transport GO:0015908 16 16 0,000 0,05443503 0,07646628 ! positive regulation of MAPKKK cascade GO:0043410 17 16 0,000 0,05443503 0,07640804 ! cellular response to nutrient levels GO:0031669 16 16 0,000 0,05443503 0,07634989 ! regulation of microtubule cytoskeleton organization GO:0070507 16 16 0,000 0,05443503 0,07629183 ! ethanolamine and derivative metabolic process GO:0042439 17 16 0,000 0,05443503 0,07623386 ! polyol metabolic process GO:0019751 16 16 0,000 0,05443503 0,07617598 ! serine family amino acid metabolic process GO:0009069 16 16 0,000 0,05443503 0,07611818 ! glutamine family amino acid catabolic process GO:0009065 17 16 0,000 0,05443503 0,07606047 ! porphyrin metabolic process GO:0006778 16 16 0,000 0,05443503 0,07600285 GO:0033013|tetrapyrrole metabolic process, ! embryonic epithelial tube formation GO:0001838 17 16 0,000 0,05443503 0,07594532 GO:0001841|neural tube formation, ! regulation of JUN kinase activity GO:0043506 17 16 0,000 0,05443503 0,07588787 GO:0043507|positive regulation of JUN kinase activity, ! regulation of cell morphogenesis involved in differentiation GO:0010769 17 16 0,000 0,05443503 0,07583051 ! response to xenobiotic stimulus GO:0009410 16 16 0,000 0,05443503 0,07577323 ! regulation of coagulation GO:0050818 17 16 0,000 0,05443503 0,07571605 ! regulation of fibroblast proliferation GO:0048145 17 17 0,000 0,0577412 0,08025417 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 17 17 0,000 0,0577412 0,0801937 ! regulation of actin filament depolymerization GO:0030834 17 17 0,000 0,0577412 0,08013331 ! positive regulation of cell adhesion GO:0045785 17 17 0,000 0,0577412 0,08007301 ! myelination GO:0042552 17 17 0,000 0,0577412 0,08001281 ! phosphoinositide biosynthetic process GO:0046489 17 17 0,000 0,0577412 0,07995269 ! regulation of transmembrane transport GO:0034762 17 17 0,000 0,0577412 0,07989267 ! nucleotide-excision repair, DNA damage removal GO:0000718 18 17 0,000 0,0577412 0,07983273 ! leukocyte adhesion GO:0007159 17 17 0,000 0,0577412 0,07977289 ! sensory perception of smell GO:0007608 17 17 0,000 0,0577412 0,07971314 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 17 17 0,000 0,0577412 0,07965347 ! embryonic skeletal system morphogenesis GO:0048704 17 17 0,000 0,0577412 0,07959389 ! cellular carbohydrate biosynthetic process GO:0034637 17 17 0,000 0,0577412 0,07953441 ! development of primary male sexual characteristics GO:0046546 17 17 0,000 0,0577412 0,07947501 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 17 17 0,000 0,0577412 0,0794157 ! response to toxin GO:0009636 18 17 0,000 0,0577412 0,07935648 ! negative regulation of cell development GO:0010721 18 17 0,000 0,0577412 0,07929734 GO:0050768|negative regulation of neurogenesis, ! immune response-activating signal transduction GO:0002757 17 17 0,000 0,0577412 0,0792383 GO:0002764|immune response-regulating signal transduction, ! cell recognition GO:0008037 18 17 0,000 0,0577412 0,07917934 ! positive regulation of protein secretion GO:0050714 17 17 0,000 0,0577412 0,07912047 ! regulation of osteoblast differentiation GO:0045667 17 17 0,000 0,0577412 0,07906169 ! pyridine nucleotide metabolic process GO:0019362 17 17 0,000 0,0577412 0,079003 ! pigmentation GO:0043473 17 17 0,000 0,0577412 0,07894439 ! myeloid leukocyte activation GO:0002274 18 17 0,000 0,0577412 0,07888587 ! adult locomotory behavior GO:0008344 17 17 0,000 0,0577412 0,07882743 ! regulation of calcium ion transport GO:0051924 17 17 0,000 0,0577412 0,07876909 ! liver development GO:0001889 17 17 0,000 0,0577412 0,07871082 ! gene silencing GO:0016458 17 17 0,000 0,0577412 0,07865265 ! mRNA export from nucleus GO:0006406 18 18 0,000 0,06103629 0,08307968 ! icosanoid biosynthetic process GO:0046456 18 18 0,000 0,06103629 0,08301837 ! regulation of metal ion transport GO:0010959 18 18 0,000 0,06103629 0,08295714 ! membrane docking GO:0022406 18 18 0,000 0,06103629 0,08289601 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 18 18 0,000 0,06103629 0,08283497 ! mononuclear cell proliferation GO:0032943 18 18 0,000 0,06103629 0,08277402 GO:0070661|leukocyte proliferation, ! response to calcium ion GO:0051592 18 18 0,000 0,06103629 0,08271315 ! negative regulation of response to external stimulus GO:0032102 18 18 0,000 0,06103629 0,08265238 ! cholesterol homeostasis GO:0042632 18 18 0,000 0,06103629 0,08259169 GO:0055092|sterol homeostasis, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 18 18 0,000 0,06103629 0,0825311 ! striated muscle contraction GO:0006941 18 18 0,000 0,06103629 0,08247059 ! neutral lipid metabolic process GO:0006638 18 18 0,000 0,06103629 0,08241017 GO:0006639|acylglycerol metabolic process, ! negative regulation of DNA binding GO:0043392 19 18 0,000 0,06103629 0,08234985 ! ceramide metabolic process GO:0006672 18 18 0,000 0,06103629 0,0822896 GO:0046519|sphingoid metabolic process, ! ribonucleoside monophosphate metabolic process GO:0009161 18 18 0,000 0,06103629 0,08222945 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! telencephalon development GO:0021537 19 18 0,000 0,06103629 0,08216939 ! hexose biosynthetic process GO:0019319 18 18 0,000 0,06103629 0,08210941 ! negative regulation of MAP kinase activity GO:0043407 18 18 0,000 0,06103629 0,08204952 ! B cell differentiation GO:0030183 18 18 0,000 0,06103629 0,08198971 ! cellular response to extracellular stimulus GO:0031668 18 18 0,000 0,06103629 0,08193 ! ensheathment of neurons GO:0007272 18 18 0,000 0,06103629 0,08187037 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 18 18 0,000 0,06103629 0,08181083 ! regulation of microtubule-based process GO:0032886 18 18 0,000 0,06103629 0,08175137 ! negative regulation of catabolic process GO:0009895 18 18 0,000 0,06103629 0,081692 ! establishment of vesicle localization GO:0051650 19 18 0,000 0,06103629 0,08163272 ! activation of adenylate cyclase activity GO:0007190 19 19 0,000 0,06432034 0,08596257 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 19 19 0,000 0,06432034 0,08590028 GO:0006956|complement activation, ! negative regulation of DNA metabolic process GO:0051053 19 19 0,000 0,06432034 0,08583808 ! glial cell differentiation GO:0010001 19 19 0,000 0,06432034 0,08577597 ! regulation of pH GO:0006885 19 19 0,000 0,06432034 0,08571395 ! feeding behavior GO:0007631 19 19 0,000 0,06432034 0,08565201 ! peroxisome organization GO:0007031 19 19 0,000 0,06432034 0,08559017 ! positive regulation of T cell proliferation GO:0042102 19 19 0,000 0,06432034 0,08552842 ! regulation of striated muscle tissue development GO:0016202 20 19 0,000 0,06432034 0,08546675 ! metanephros development GO:0001656 19 19 0,000 0,06432034 0,08540518 ! ribonucleoside metabolic process GO:0009119 19 19 0,000 0,06432034 0,08534369 ! regulation of lymphocyte mediated immunity GO:0002706 19 19 0,000 0,06432034 0,08528229 ! positive regulation of T cell differentiation GO:0045582 19 19 0,000 0,06432034 0,08522098 ! nuclear-transcribed mRNA catabolic process GO:0000956 19 19 0,000 0,06432034 0,08515976 ! peripheral nervous system development GO:0007422 19 19 0,000 0,06432034 0,08509863 ! regulation of protein stability GO:0031647 19 19 0,000 0,06432034 0,08503758 ! hormone biosynthetic process GO:0042446 19 19 0,000 0,06432034 0,08497662 ! biogenic amine biosynthetic process GO:0042401 20 19 0,000 0,06432034 0,08491575 ! dorsal/ventral pattern formation GO:0009953 19 19 0,000 0,06432034 0,08485497 ! eye morphogenesis GO:0048592 19 19 0,000 0,06432034 0,08479427 ! response to heat GO:0009408 19 19 0,000 0,06432034 0,08473366 ! vesicle localization GO:0051648 20 19 0,000 0,06432034 0,08467313 ! regulation of muscle development GO:0048634 21 20 0,000 0,06759338 0,08891834 ! negative regulation of binding GO:0051100 21 20 0,000 0,06759338 0,08885492 ! organic ether metabolic process GO:0018904 20 20 0,000 0,06759338 0,08879159 GO:0006662|glycerol ether metabolic process, ! cytoskeleton-dependent intracellular transport GO:0030705 20 20 0,000 0,06759338 0,08872834 ! neural tube development GO:0021915 21 20 0,000 0,06759338 0,08866519 ! nucleus organization GO:0006997 20 20 0,000 0,06759338 0,08860213 ! phagocytosis GO:0006909 21 20 0,000 0,06759338 0,08853916 ! unsaturated fatty acid biosynthetic process GO:0006636 20 20 0,000 0,06759338 0,08847627 ! protein targeting to membrane GO:0006612 22 20 0,000 0,06759338 0,08841348 ! cyclic nucleotide metabolic process GO:0009187 20 20 0,000 0,06759338 0,08835078 ! chromatin remodeling GO:0006338 20 20 0,000 0,06759338 0,08828816 ! detection of abiotic stimulus GO:0009582 21 20 0,000 0,06759338 0,08822563 ! lipid oxidation GO:0034440 20 20 0,000 0,06759338 0,0881632 GO:0019395|fatty acid oxidation, ! female gamete generation GO:0007292 20 20 0,000 0,06759338 0,08810085 ! monosaccharide biosynthetic process GO:0046364 20 20 0,000 0,06759338 0,08803858 ! RNA modification GO:0009451 20 20 0,000 0,06759338 0,08797641 ! single fertilization GO:0007338 21 20 0,000 0,06759338 0,08791432 ! regulation of B cell activation GO:0050864 20 20 0,000 0,06759338 0,08785232 ! mRNA catabolic process GO:0006402 21 21 0,000 0,07085544 0,09202719 ! positive regulation of adenylate cyclase activity GO:0045762 21 21 0,000 0,07085544 0,09196238 GO:0051349|positive regulation of lyase activity, GO:0031281|positive regulation of cyclase activity, ! mammary gland development GO:0030879 23 21 0,000 0,07085544 0,09189766 ! protein amino acid lipidation GO:0006497 21 21 0,000 0,07085544 0,09183304 ! receptor-mediated endocytosis GO:0006898 21 21 0,000 0,07085544 0,0917685 ! Notch signaling pathway GO:0007219 22 21 0,000 0,07085544 0,09170406 ! morphogenesis of embryonic epithelium GO:0016331 22 21 0,000 0,07085544 0,0916397 ! ear morphogenesis GO:0042471 21 21 0,000 0,07085544 0,09157544 ! organic anion transport GO:0015711 21 21 0,000 0,07085544 0,09151127 ! cholesterol transport GO:0030301 21 21 0,000 0,07085544 0,09144718 GO:0015918|sterol transport, ! spliceosome assembly GO:0000245 22 21 0,000 0,07085544 0,09138319 ! regulation of Rab protein signal transduction GO:0032483 21 21 0,000 0,07085544 0,09131929 GO:0032313|regulation of Rab GTPase activity, ! regulation of protein import into nucleus GO:0042306 21 21 0,000 0,07085544 0,09125547 ! regulation of leukocyte mediated immunity GO:0002703 21 21 0,000 0,07085544 0,09119175 ! regulation of action potential in neuron GO:0019228 21 21 0,000 0,07085544 0,09112811 ! regulation of proteolysis GO:0030162 21 21 0,000 0,07085544 0,09106456 ! negative regulation of hydrolase activity GO:0051346 21 21 0,000 0,07085544 0,0910011 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 21 21 0,000 0,07085544 0,09093773 ! negative regulation of protein transport GO:0051224 21 21 0,000 0,07085544 0,09087445 ! RNA export from nucleus GO:0006405 22 22 0,000 0,07410657 0,09497803 ! regulation of ion transport GO:0043269 22 22 0,000 0,07410657 0,09491202 ! odontogenesis GO:0042476 22 22 0,000 0,07410657 0,09484611 ! positive regulation of lymphocyte proliferation GO:0050671 22 22 0,000 0,07410657 0,09478029 GO:0032946|positive regulation of mononuclear cell proliferation, GO:0070665|positive regulation of leukocyte proliferation, GO:0070668|positive regulation of mast cell proliferation, ! hormone-mediated signaling GO:0009755 22 22 0,000 0,07410657 0,09471457 ! embryonic skeletal system development GO:0048706 22 22 0,000 0,07410657 0,09464893 ! maintenance of protein location in cell GO:0032507 23 22 0,000 0,07410657 0,09458338 ! ovulation cycle process GO:0022602 22 22 0,000 0,07410657 0,09451793 ! pigment biosynthetic process GO:0046148 22 22 0,000 0,07410657 0,09445256 ! cell chemotaxis GO:0060326 23 22 0,000 0,07410657 0,09438729 GO:0030595|leukocyte chemotaxis, ! respiratory gaseous exchange GO:0007585 22 22 0,000 0,07410657 0,0943221 ! erythrocyte differentiation GO:0030218 23 22 0,000 0,07410657 0,09425701 ! male sex differentiation GO:0046661 22 22 0,000 0,07410657 0,094192 ! sterol biosynthetic process GO:0016126 22 22 0,000 0,07410657 0,09412709 ! biopolymer methylation GO:0043414 22 22 0,000 0,07410657 0,09406226 GO:0032259|methylation, ! regulation of adaptive immune response GO:0002819 22 22 0,000 0,07410657 0,09399752 ! detection of external stimulus GO:0009581 23 22 0,000 0,07410657 0,09393288 ! regulation of Wnt receptor signaling pathway GO:0030111 23 22 0,000 0,07410657 0,09386832 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 22 22 0,000 0,07410657 0,09380385 ! positive regulation of lymphocyte differentiation GO:0045621 22 22 0,000 0,07410657 0,09373947 ! fatty acid catabolic process GO:0009062 23 22 0,000 0,07410657 0,09367517 ! cytokine production GO:0001816 22 22 0,000 0,07410657 0,09361097 ! pyrimidine nucleotide metabolic process GO:0006220 22 22 0,000 0,07410657 0,09354685 ! response to hydrogen peroxide GO:0042542 24 23 0,000 0,07734679 0,09757025 ! epithelial cell differentiation GO:0030855 23 23 0,000 0,07734679 0,09750351 ! viral infectious cycle GO:0019058 23 23 0,000 0,07734679 0,09743686 ! regulation of hormone secretion GO:0046883 23 23 0,000 0,07734679 0,09737031 ! response to estrogen stimulus GO:0043627 23 23 0,000 0,07734679 0,09730384 ! negative regulation of protein complex disassembly GO:0043242 23 23 0,000 0,07734679 0,09723747 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 23 23 0,000 0,07734679 0,09717119 ! induction of apoptosis by extracellular signals GO:0008624 23 23 0,000 0,07734679 0,09710499 ! regulation of ARF protein signal transduction GO:0032012 23 23 0,000 0,07734679 0,09703889 ! endocrine system development GO:0035270 23 23 0,000 0,07734679 0,09697288 ! lipoprotein biosynthetic process GO:0042158 23 23 0,000 0,07734679 0,09690696 ! female gonad development GO:0008585 23 23 0,000 0,07734679 0,09684112 ! monovalent inorganic cation homeostasis GO:0055067 23 23 0,000 0,07734679 0,09677538 ! lipid homeostasis GO:0055088 23 23 0,000 0,07734679 0,09670972 ! Rho protein signal transduction GO:0007266 24 23 0,000 0,07734679 0,09664416 ! regulation of JNK cascade GO:0046328 25 23 0,000 0,07734679 0,09657868 ! mitochondrial transport GO:0006839 24 24 0,000 0,08057614 0,10054288 ! regulation of action potential GO:0001508 24 24 0,000 0,08057614 0,10047485 ! gliogenesis GO:0042063 24 24 0,000 0,08057614 0,10040692 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 26 24 0,000 0,08057614 0,10033907 ! cellular amino acid biosynthetic process GO:0008652 24 24 0,000 0,08057614 0,10027132 ! heterocycle biosynthetic process GO:0018130 24 24 0,000 0,08057614 0,10020366 ! T cell differentiation GO:0030217 24 24 0,000 0,08057614 0,1001361 ! nucleotide catabolic process GO:0009166 24 24 0,000 0,08057614 0,10006862 ! erythrocyte homeostasis GO:0034101 25 24 0,000 0,08057614 0,10000123 ! ovulation cycle GO:0042698 24 24 0,000 0,08057614 0,09993394 ! fertilization GO:0009566 25 24 0,000 0,08057614 0,09986673 ! maintenance of protein location GO:0045185 25 24 0,000 0,08057614 0,09979962 ! oxidoreduction coenzyme metabolic process GO:0006733 24 24 0,000 0,08057614 0,09973259 ! androgen receptor signaling pathway GO:0030521 24 24 0,000 0,08057614 0,09966566 ! epithelial tube morphogenesis GO:0060562 25 24 0,000 0,08057614 0,09959881 ! glucan metabolic process GO:0044042 25 24 0,000 0,08057614 0,09953206 GO:0006073|cellular glucan metabolic process, GO:0005977|glycogen metabolic process, ! negative regulation of secretion GO:0051048 26 25 0,000 0,08379466 0,10343842 ! protein amino acid N-linked glycosylation GO:0006487 25 25 0,000 0,08379466 0,10336919 ! sensory perception of chemical stimulus GO:0007606 25 25 0,000 0,08379466 0,10330004 ! cellular component disassembly GO:0022411 26 25 0,000 0,08379466 0,10323099 ! endosome transport GO:0016197 25 25 0,000 0,08379466 0,10316203 ! alcohol biosynthetic process GO:0046165 25 25 0,000 0,08379466 0,10309317 ! regulation of intracellular protein transport GO:0033157 25 25 0,000 0,08379466 0,10302439 ! development of primary female sexual characteristics GO:0046545 25 25 0,000 0,08379466 0,10295571 GO:0046660|female sex differentiation, ! polysaccharide biosynthetic process GO:0000271 25 25 0,000 0,08379466 0,10288712 ! regulation of T cell proliferation GO:0042129 25 25 0,000 0,08379466 0,10281862 ! excretion GO:0007588 25 25 0,000 0,08379466 0,10275021 ! generation of a signal involved in cell-cell signaling GO:0003001 27 25 0,000 0,08379466 0,10268189 ! gastrulation GO:0007369 25 25 0,000 0,08379466 0,10261366 ! icosanoid metabolic process GO:0006690 25 25 0,000 0,08379466 0,10254553 ! regulation of endocytosis GO:0030100 25 25 0,000 0,08379466 0,10247748 ! negative regulation of immune system process GO:0002683 25 25 0,000 0,08379466 0,10240952 ! positive regulation of defense response GO:0031349 26 26 0,000 0,08700238 0,10625937 ! transforming growth factor beta receptor signaling pathway GO:0007179 26 26 0,000 0,08700238 0,106189 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 26 26 0,000 0,08700238 0,10611872 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 26 26 0,000 0,08700238 0,10604854 ! induction of apoptosis by intracellular signals GO:0008629 26 26 0,000 0,08700238 0,10597845 ! cellular defense response GO:0006968 26 26 0,000 0,08700238 0,10590845 ! positive regulation of cytokine biosynthetic process GO:0042108 26 26 0,000 0,08700238 0,10583854 ! regulation of T cell differentiation GO:0045580 26 26 0,000 0,08700238 0,10576873 ! double-strand break repair GO:0006302 27 26 0,000 0,08700238 0,10569901 ! regulation of protein secretion GO:0050708 26 26 0,000 0,08700238 0,10562938 ! germ cell development GO:0007281 27 26 0,000 0,08700238 0,10555984 ! regulation of blood vessel size GO:0050880 27 26 0,000 0,08700238 0,10549039 GO:0035150|regulation of tube size, ! pigment metabolic process GO:0042440 26 26 0,000 0,08700238 0,10542103 ! maintenance of location in cell GO:0051651 27 26 0,000 0,08700238 0,10535177 ! synapse organization GO:0050808 26 26 0,000 0,08700238 0,1052826 ! chloride transport GO:0006821 27 27 0,000 0,09019934 0,10907965 ! regulation of nucleocytoplasmic transport GO:0046822 27 27 0,000 0,09019934 0,10900812 ! regulation of neurotransmitter levels GO:0001505 31 27 0,000 0,09019934 0,10893669 ! energy reserve metabolic process GO:0006112 28 27 0,000 0,09019934 0,10886535 ! learning or memory GO:0007611 28 27 0,000 0,09019934 0,1087941 ! monocarboxylic acid transport GO:0015718 27 27 0,000 0,09019934 0,10872295 ! cAMP-mediated signaling GO:0019933 27 27 0,000 0,09019934 0,10865189 ! peptide metabolic process GO:0006518 29 27 0,000 0,09019934 0,10858092 ! activation of caspase activity GO:0006919 27 27 0,000 0,09019934 0,10851004 ! inner ear development GO:0048839 27 27 0,000 0,09019934 0,10843926 ! defense response to bacterium GO:0042742 27 27 0,000 0,09019934 0,10836857 ! isoprenoid metabolic process GO:0006720 27 27 0,000 0,09019934 0,10829797 ! glutamine family amino acid metabolic process GO:0009064 28 27 0,000 0,09019934 0,10822746 ! cell growth GO:0016049 27 27 0,000 0,09019934 0,10815705 ! tRNA aminoacylation for protein translation GO:0006418 28 28 0,000 0,09338557 0,11190481 GO:0043038|amino acid activation, GO:0043039|tRNA aminoacylation, ! stress-activated protein kinase signaling pathway GO:0031098 28 28 0,000 0,09338557 0,1118321 GO:0007254|JNK cascade, ! neuromuscular process GO:0050905 28 28 0,000 0,09338557 0,11175948 ! regulation of muscle contraction GO:0006937 28 28 0,000 0,09338557 0,11168696 ! unsaturated fatty acid metabolic process GO:0033559 28 28 0,000 0,09338557 0,11161453 ! sulfur compound biosynthetic process GO:0044272 28 28 0,000 0,09338557 0,11154219 ! keratinocyte differentiation GO:0030216 28 28 0,000 0,09338557 0,11146995 ! developmental growth GO:0048589 28 28 0,000 0,09338557 0,1113978 ! regulation of mast cell proliferation GO:0070666 28 28 0,000 0,09338557 0,11132574 ! glycerophospholipid biosynthetic process GO:0046474 30 29 0,000 0,0965611 0,11503691 ! phosphoinositide metabolic process GO:0030384 29 29 0,000 0,0965611 0,1149626 ! leukocyte migration GO:0050900 30 29 0,000 0,0965611 0,11488838 ! branching morphogenesis of a tube GO:0048754 29 29 0,000 0,0965611 0,11481426 ! regulation of lymphocyte proliferation GO:0050670 29 29 0,000 0,0965611 0,11474024 GO:0032944|regulation of mononuclear cell proliferation, GO:0070663|regulation of leukocyte proliferation, ! antigen processing and presentation GO:0019882 29 29 0,000 0,0965611 0,11466631 ! DNA-dependent DNA replication GO:0006261 29 29 0,000 0,0965611 0,11459247 ! tRNA processing GO:0008033 29 29 0,000 0,0965611 0,11451873 ! regulation of gene expression, epigenetic GO:0040029 29 29 0,000 0,0965611 0,11444509 ! adult behavior GO:0030534 30 29 0,000 0,0965611 0,11437153 ! positive regulation of protein transport GO:0051222 29 29 0,000 0,0965611 0,11429808 ! transition metal ion transport GO:0000041 31 30 0,000 0,09972597 0,11796853 ! RNA catabolic process GO:0006401 30 30 0,000 0,09972597 0,11789286 ! response to reactive oxygen species GO:0000302 31 30 0,000 0,09972597 0,11781729 ! ER to Golgi vesicle-mediated transport GO:0006888 30 30 0,000 0,09972597 0,11774181 ! positive regulation of peptidase activity GO:0010952 30 30 0,000 0,09972597 0,11766643 GO:0043280|positive regulation of caspase activity, ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 30 30 0,000 0,09972597 0,11759115 ! neuropeptide signaling pathway GO:0007218 30 30 0,000 0,09972597 0,11751596 ! regulation of protein complex disassembly GO:0043244 30 30 0,000 0,09972597 0,11744087 ! response to temperature stimulus GO:0009266 30 30 0,000 0,09972597 0,11736588 ! regulation of ossification GO:0030278 30 30 0,000 0,09972597 0,11729098 ! immunoglobulin mediated immune response GO:0016064 30 30 0,000 0,09972597 0,11721618 GO:0019724|B cell mediated immunity, ! regulation of inflammatory response GO:0050727 30 30 0,000 0,09972597 0,11714147 ! water-soluble vitamin metabolic process GO:0006767 30 30 0,000 0,09972597 0,11706686 ! vesicle organization GO:0016050 30 30 0,000 0,09972597 0,11699234 ! cellular amino acid derivative biosynthetic process GO:0042398 31 30 0,000 0,09972597 0,11691792 ! regulation of translational initiation GO:0006446 31 31 0,000 0,10288022 0,12053925 ! skeletal muscle fiber development GO:0048741 31 31 0,000 0,10288022 0,12046267 ! B cell activation GO:0042113 31 31 0,000 0,10288022 0,12038618 ! negative regulation of cytoskeleton organization GO:0051494 32 31 0,000 0,10288022 0,1203098 ! lipoprotein metabolic process GO:0042157 31 31 0,000 0,10288022 0,12023351 ! ion transmembrane transport GO:0034220 31 31 0,000 0,10288022 0,12015731 GO:0015985|energy coupled proton transport, down electrochemical gradient, GO:0015986|ATP synthesis coupled proton transport, ! aging GO:0007568 32 31 0,000 0,10288022 0,12008121 ! glycerolipid biosynthetic process GO:0045017 32 31 0,000 0,10288022 0,12000521 ! digestion GO:0007586 31 31 0,000 0,10288022 0,11992931 ! nucleoside metabolic process GO:0009116 31 31 0,000 0,10288022 0,1198535 ! regulation of heart contraction GO:0008016 31 31 0,000 0,10288022 0,11977779 ! sphingolipid metabolic process GO:0006665 31 31 0,000 0,10288022 0,11970217 ! camera-type eye development GO:0043010 31 31 0,000 0,10288022 0,11962665 ! extracellular matrix organization GO:0030198 31 31 0,000 0,10288022 0,11955122 ! ribonucleoprotein complex assembly GO:0022618 32 31 0,000 0,10288022 0,11947589 ! regulation of intracellular transport GO:0032386 31 31 0,000 0,10288022 0,11940065 ! epidermal cell differentiation GO:0009913 31 31 0,000 0,10288022 0,11932551 ! negative regulation of cell growth GO:0030308 32 32 0,000 0,10602387 0,12289433 ! cell redox homeostasis GO:0045454 32 32 0,000 0,10602387 0,12281709 ! muscle fiber development GO:0048747 32 32 0,000 0,10602387 0,12273994 ! lipid modification GO:0030258 32 32 0,000 0,10602387 0,12266289 ! glycosaminoglycan metabolic process GO:0030203 34 32 0,000 0,10602387 0,12258594 ! regulation of vesicle-mediated transport GO:0060627 33 32 0,000 0,10602387 0,12250908 ! cell maturation GO:0048469 32 32 0,000 0,10602387 0,12243232 ! morphogenesis of a branching structure GO:0001763 32 32 0,000 0,10602387 0,12235566 ! nuclear export GO:0051168 32 32 0,000 0,10602387 0,12227909 ! regulation of lymphocyte differentiation GO:0045619 32 32 0,000 0,10602387 0,12220262 ! kidney development GO:0001822 32 32 0,000 0,10602387 0,12212624 ! protein maturation by peptide bond cleavage GO:0051605 32 32 0,000 0,10602387 0,12204996 ! maintenance of location GO:0051235 33 32 0,000 0,10602387 0,12197378 ! negative regulation of cell size GO:0045792 33 33 0,000 0,10915696 0,12549986 ! regulation of cellular response to stress GO:0080135 35 33 0,000 0,10915696 0,12542162 ! amino acid transport GO:0006865 33 33 0,000 0,10915696 0,12534348 ! membrane lipid metabolic process GO:0006643 33 33 0,000 0,10915696 0,12526543 ! regulation of neuron differentiation GO:0045664 34 33 0,000 0,10915696 0,12518748 ! regulation of synaptic transmission GO:0050804 33 33 0,000 0,10915696 0,12510963 ! response to metal ion GO:0010038 34 34 0,000 0,11227953 0,12860856 ! ear development GO:0043583 34 34 0,000 0,11227953 0,12852868 ! muscle cell differentiation GO:0042692 35 34 0,000 0,11227953 0,1284489 ! cellular polysaccharide metabolic process GO:0044264 35 34 0,000 0,11227953 0,12836922 ! regulation of protein catabolic process GO:0042176 35 34 0,000 0,11227953 0,12828963 ! coenzyme biosynthetic process GO:0009108 34 34 0,000 0,11227953 0,12821015 ! nucleoside monophosphate biosynthetic process GO:0009124 34 34 0,000 0,11227953 0,12813076 ! secondary metabolic process GO:0019748 34 34 0,000 0,11227953 0,12805147 ! negative regulation of response to stimulus GO:0048585 34 34 0,000 0,11227953 0,12797228 ! detection of stimulus GO:0051606 36 34 0,000 0,11227953 0,12789319 ! acute inflammatory response GO:0002526 35 35 0,000 0,11539161 0,13135685 ! regulation of cytokine biosynthetic process GO:0042035 35 35 0,000 0,11539161 0,13127576 ! multicellular organism reproduction GO:0032504 36 35 0,000 0,11539161 0,13119478 GO:0048609|reproductive process in a multicellular organism, ! inorganic anion transport GO:0015698 35 35 0,000 0,11539161 0,1311139 ! response to steroid hormone stimulus GO:0048545 35 35 0,000 0,11539161 0,13103311 ! regulation of immune effector process GO:0002697 35 35 0,000 0,11539161 0,13095243 ! hydrogen transport GO:0006818 36 36 0,000 0,11849323 0,13438956 GO:0015992|proton transport, ! response to inorganic substance GO:0010035 36 36 0,000 0,11849323 0,1343069 ! aminoglycan metabolic process GO:0006022 38 36 0,000 0,11849323 0,13422436 ! oxygen and reactive oxygen species metabolic process GO:0006800 37 36 0,000 0,11849323 0,13414191 ! embryonic limb morphogenesis GO:0030326 36 36 0,000 0,11849323 0,13405956 GO:0035113|embryonic appendage morphogenesis, ! female pregnancy GO:0007565 37 36 0,000 0,11849323 0,13397732 ! RNA elongation from RNA polymerase II promoter GO:0006368 36 36 0,000 0,11849323 0,13389517 ! heterocycle catabolic process GO:0046700 36 36 0,000 0,11849323 0,13381313 ! regulation of transmission of nerve impulse GO:0051969 36 36 0,000 0,11849323 0,13373119 ! gonad development GO:0008406 36 36 0,000 0,11849323 0,13364934 ! activation of immune response GO:0002253 36 36 0,000 0,11849323 0,1335676 ! coagulation GO:0050817 39 36 0,000 0,11849323 0,13348596 GO:0007596|blood coagulation, ! response to drug GO:0042493 37 37 0,000 0,12158443 0,13688461 ! lymphocyte mediated immunity GO:0002449 37 37 0,000 0,12158443 0,13680104 ! eye development GO:0001654 37 37 0,000 0,12158443 0,13671758 ! ATP synthesis coupled electron transport GO:0042773 37 37 0,000 0,12158443 0,13663421 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! cellular amino acid catabolic process GO:0009063 38 37 0,000 0,12158443 0,13655095 ! positive regulation of secretion GO:0051047 39 38 0,000 0,12466524 0,13992572 ! neurotransmitter transport GO:0006836 40 38 0,000 0,12466524 0,13984056 ! cellular hormone metabolic process GO:0034754 39 38 0,000 0,12466524 0,1397555 ! exocytosis GO:0006887 40 38 0,000 0,12466524 0,13967054 ! urogenital system development GO:0001655 38 38 0,000 0,12466524 0,13958568 ! RNA elongation GO:0006354 38 38 0,000 0,12466524 0,13950093 ! axon guidance GO:0007411 39 38 0,000 0,12466524 0,13941628 ! regulation of neurological system process GO:0031644 38 38 0,000 0,12466524 0,13933174 ! steroid hormone receptor signaling pathway GO:0030518 38 38 0,000 0,12466524 0,13924729 ! hemostasis GO:0007599 42 39 0,000 0,12773569 0,14259048 ! response to unfolded protein GO:0006986 39 39 0,000 0,12773569 0,14250416 ! nucleoside monophosphate metabolic process GO:0009123 39 39 0,000 0,12773569 0,14241796 ! fatty acid biosynthetic process GO:0006633 39 39 0,000 0,12773569 0,14233185 ! nucleotide-excision repair GO:0006289 40 39 0,000 0,12773569 0,14224585 ! cytokine-mediated signaling pathway GO:0019221 39 39 0,000 0,12773569 0,14215995 ! intracellular protein transmembrane transport GO:0065002 39 39 0,000 0,12773569 0,14207416 ! regulation of MAPKKK cascade GO:0043408 41 39 0,000 0,12773569 0,14198847 ! positive regulation of T cell activation GO:0050870 39 39 0,000 0,12773569 0,14190288 ! developmental maturation GO:0021700 39 39 0,000 0,12773569 0,1418174 ! lymphocyte differentiation GO:0030098 39 39 0,000 0,12773569 0,14173202 ! limb development GO:0060173 39 39 0,000 0,12773569 0,14164674 GO:0048736|appendage development, GO:0035107|appendage morphogenesis, ! DNA catabolic process GO:0006308 41 40 0,000 0,13079582 0,14495292 ! intracellular receptor-mediated signaling pathway GO:0030522 40 40 0,000 0,13079582 0,1448658 ! amine catabolic process GO:0009310 42 41 0,000 0,13384566 0,14815469 ! elevation of cytosolic calcium ion concentration GO:0007204 41 41 0,000 0,13384566 0,14806576 ! regulation of caspase activity GO:0043281 41 41 0,000 0,13384566 0,14797694 ! phospholipid biosynthetic process GO:0008654 42 41 0,000 0,13384566 0,14788822 ! leukocyte mediated immunity GO:0002443 41 41 0,000 0,13384566 0,14779961 ! regulation of Ras GTPase activity GO:0032318 41 41 0,000 0,13384566 0,14771111 ! respiratory electron transport chain GO:0022904 43 42 0,000 0,13688524 0,15097517 ! regulation of endopeptidase activity GO:0052548 42 42 0,000 0,13688524 0,15088487 ! cytosolic calcium ion homeostasis GO:0051480 42 42 0,000 0,13688524 0,15079468 ! development of primary sexual characteristics GO:0045137 42 42 0,000 0,13688524 0,1507046 ! protein ubiquitination GO:0016567 43 42 0,000 0,13688524 0,15061463 ! negative regulation of ligase activity GO:0051352 43 42 0,000 0,13688524 0,15052476 GO:0051444|negative regulation of ubiquitin-protein ligase activity, GO:0051436|negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle, ! response to protein stimulus GO:0051789 42 42 0,000 0,13688524 0,150435 ! one-carbon metabolic process GO:0006730 42 42 0,000 0,13688524 0,15034535 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 42 42 0,000 0,13688524 0,15025581 ! reproductive structure development GO:0048608 43 43 0,000 0,1399146 0,15348965 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 43 43 0,000 0,1399146 0,15339834 ! mitochondrion organization GO:0007005 44 43 0,000 0,1399146 0,15330714 ! homeostasis of number of cells GO:0048872 44 43 0,000 0,1399146 0,15321605 ! humoral immune response GO:0006959 44 44 0,000 0,14293377 0,1564293 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 45 44 0,000 0,14293377 0,15633646 ! mRNA transport GO:0051028 44 44 0,000 0,14293377 0,15624373 ! protein import into nucleus GO:0006606 44 44 0,000 0,14293377 0,15615112 ! vitamin metabolic process GO:0006766 44 44 0,000 0,14293377 0,15605861 ! positive regulation of lymphocyte activation GO:0051251 44 44 0,000 0,14293377 0,15596621 ! amine biosynthetic process GO:0009309 46 45 0,000 0,14594278 0,15915535 ! phosphoinositide-mediated signaling GO:0048015 45 45 0,000 0,14594278 0,15906123 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 46 45 0,000 0,14594278 0,15896722 ! steroid biosynthetic process GO:0006694 46 45 0,000 0,14594278 0,15887333 ! nuclear import GO:0051170 45 45 0,000 0,14594278 0,15877954 ! Wnt receptor signaling pathway GO:0016055 46 45 0,000 0,14594278 0,15868586 ! protein processing GO:0016485 45 45 0,000 0,14594278 0,1585923 ! cyclic-nucleotide-mediated signaling GO:0019935 46 46 0,000 0,14894166 0,16175574 ! tube morphogenesis GO:0035239 47 46 0,000 0,14894166 0,16166047 ! regulation of peptidase activity GO:0052547 46 46 0,000 0,14894166 0,16156532 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 47 46 0,000 0,14894166 0,16147028 ! transcription initiation from RNA polymerase II promoter GO:0006367 46 46 0,000 0,14894166 0,16137536 ! positive regulation of ligase activity GO:0051351 47 46 0,000 0,14894166 0,16128054 ! regulation of membrane potential GO:0042391 46 46 0,000 0,14894166 0,16118584 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 47 47 0,000 0,15193045 0,16432384 ! regulation of blood pressure GO:0008217 48 47 0,000 0,15193045 0,16422746 ! sex differentiation GO:0007548 47 47 0,000 0,15193045 0,1641312 ! amine transport GO:0015837 47 47 0,000 0,15193045 0,16403505 ! rhythmic process GO:0048511 47 47 0,000 0,15193045 0,16393901 ! calcium ion transport GO:0006816 48 48 0,000 0,15490919 0,16705537 ! regulation of ubiquitin-protein ligase activity GO:0051438 49 48 0,000 0,15490919 0,16695768 ! glycerophospholipid metabolic process GO:0006650 49 48 0,000 0,15490919 0,1668601 ! protein localization in nucleus GO:0034504 48 48 0,000 0,15490919 0,16676263 ! DNA recombination GO:0006310 48 48 0,000 0,15490919 0,16666528 ! gland development GO:0048732 51 49 0,000 0,15787789 0,16976018 ! cell cycle arrest GO:0007050 49 49 0,000 0,15787789 0,16966119 ! cellular lipid catabolic process GO:0044242 50 49 0,000 0,15787789 0,16956232 ! divalent metal ion transport GO:0070838 49 49 0,000 0,15787789 0,16946357 ! response to bacterium GO:0009617 50 49 0,000 0,15787789 0,16936493 ! regulation of ligase activity GO:0051340 50 49 0,000 0,15787789 0,1692664 ! cofactor biosynthetic process GO:0051188 49 49 0,000 0,15787789 0,16916799 ! positive regulation of cell activation GO:0050867 49 49 0,000 0,15787789 0,1690697 GO:0002696|positive regulation of leukocyte activation, ! regulation of defense response GO:0031347 50 50 0,000 0,1608366 0,17213812 ! negative regulation of transport GO:0051051 51 50 0,000 0,1608366 0,17203822 ! chromatin assembly GO:0031497 50 50 0,000 0,1608366 0,17193843 GO:0006334|nucleosome assembly, ! RNA transport GO:0050658 50 50 0,000 0,1608366 0,17183875 GO:0050657|nucleic acid transport, GO:0051236|establishment of RNA localization, ! T cell activation GO:0042110 51 50 0,000 0,1608366 0,17173919 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 50 50 0,000 0,1608366 0,17163975 ! nitrogen compound catabolic process GO:0044270 51 50 0,000 0,1608366 0,17154042 ! regulation of neurogenesis GO:0050767 51 50 0,000 0,1608366 0,17144121 ! transcription initiation GO:0006352 50 50 0,000 0,1608366 0,17134211 ! biogenic amine metabolic process GO:0006576 52 51 0,000 0,16378534 0,17438266 ! protein modification by small protein conjugation GO:0032446 52 51 0,000 0,16378534 0,17428198 ! positive regulation of immune response GO:0050778 51 51 0,000 0,16378534 0,17418141 ! rRNA metabolic process GO:0016072 51 51 0,000 0,16378534 0,17408096 GO:0006364|rRNA processing, ! protein-DNA complex assembly GO:0065004 51 51 0,000 0,16378534 0,17398062 ! ATP biosynthetic process GO:0006754 51 51 0,000 0,16378534 0,1738804 ! protein maturation GO:0051604 51 51 0,000 0,16378534 0,1737803 ! RNA localization GO:0006403 52 52 0,000 0,16672415 0,17679667 ! cholesterol metabolic process GO:0008203 52 52 0,000 0,16672415 0,176695 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 52 52 0,000 0,16672415 0,17659346 ! cell fate commitment GO:0045165 52 52 0,000 0,16672415 0,17649202 ! regulation of GTPase activity GO:0043087 53 52 0,000 0,16672415 0,17639071 ! regulation of body fluid levels GO:0050878 55 52 0,000 0,16672415 0,17628951 ! sodium ion transport GO:0006814 53 53 0,000 0,16965307 0,1792836 ! tRNA metabolic process GO:0006399 53 53 0,000 0,16965307 0,17918086 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 53 53 0,000 0,16965307 0,17907824 ! carbohydrate biosynthetic process GO:0016051 53 53 0,000 0,16965307 0,17897573 ! regulation of T cell activation GO:0050863 53 53 0,000 0,16965307 0,17887334 ! regulation of protein transport GO:0051223 53 53 0,000 0,16965307 0,17877107 GO:0070201|regulation of establishment of protein localization, ! protein amino acid dephosphorylation GO:0006470 55 54 0,000 0,17257211 0,18174309 ! response to virus GO:0009615 54 54 0,000 0,17257211 0,18163929 ! hormone metabolic process GO:0042445 55 54 0,000 0,17257211 0,18153562 ! nucleosome organization GO:0034728 55 55 0,000 0,17548132 0,18449063 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 55 55 0,000 0,17548132 0,18438545 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! protein modification by small protein conjugation or removal GO:0070647 56 55 0,000 0,17548132 0,18428039 ! ribonucleoside triphosphate biosynthetic process GO:0009201 56 56 0,000 0,17838073 0,1872185 ! extracellular structure organization GO:0043062 56 56 0,000 0,17838073 0,18711194 ! regulation of nervous system development GO:0051960 57 56 0,000 0,17838073 0,18700551 ! ATP metabolic process GO:0046034 57 57 0,000 0,18127036 0,18992682 ! nucleoside triphosphate biosynthetic process GO:0009142 57 57 0,000 0,18127036 0,18981891 ! regulation of protein localization GO:0032880 58 57 0,000 0,18127036 0,18971112 ! innate immune response GO:0045087 58 58 0,000 0,18415026 0,19261573 ! dephosphorylation GO:0016311 60 59 0,000 0,18702044 0,1955069 ! carboxylic acid transport GO:0046942 59 59 0,000 0,18702044 0,19539607 GO:0015849|organic acid transport, ! regulation of cell development GO:0060284 60 59 0,000 0,18702044 0,19528537 ! sterol metabolic process GO:0016125 59 59 0,000 0,18702044 0,19517478 ! cellular aromatic compound metabolic process GO:0006725 60 59 0,000 0,18702044 0,19506433 ! protein localization in organelle GO:0033365 59 59 0,000 0,18702044 0,194954 ! immune effector process GO:0002252 59 59 0,000 0,18702044 0,19484379 ! potassium ion transport GO:0006813 60 60 0,000 0,18988094 0,19771219 ! negative regulation of cellular protein metabolic process GO:0032269 60 60 0,000 0,18988094 0,19760055 ! protein polymerization GO:0051258 65 60 0,000 0,18988094 0,19748904 ! proteasomal protein catabolic process GO:0010498 62 61 0,000 0,1927318 0,20034107 GO:0043161|proteasomal ubiquitin-dependent protein catabolic process, ! carboxylic acid catabolic process GO:0046395 63 61 0,000 0,1927318 0,20022814 GO:0016054|organic acid catabolic process, ! lipid transport GO:0006869 62 62 0,000 0,19557305 0,20306542 ! purine ribonucleoside triphosphate metabolic process GO:0009205 62 62 0,000 0,19557305 0,20295108 ! morphogenesis of an epithelium GO:0002009 63 62 0,000 0,19557305 0,20283687 GO:0060429|epithelium development, ! axonogenesis GO:0007409 66 62 0,000 0,19557305 0,20272279 ! protein import GO:0017038 62 62 0,000 0,19557305 0,20260884 ! di-, tri-valent inorganic cation transport GO:0015674 63 62 0,000 0,19557305 0,20249501 ! regulation of lymphocyte activation GO:0051249 62 62 0,000 0,19557305 0,20238132 ! regulation of secretion GO:0051046 65 63 0,000 0,19840471 0,20519634 ! ribonucleoside triphosphate metabolic process GO:0009199 63 63 0,000 0,19840471 0,20508125 ! purine nucleoside triphosphate metabolic process GO:0009144 63 63 0,000 0,19840471 0,2049663 ! glycerolipid metabolic process GO:0046486 65 64 0,000 0,20122681 0,20776527 ! anion transport GO:0006820 65 65 0,000 0,20403939 0,21055129 ! regulation of hormone levels GO:0010817 66 65 0,000 0,20403939 0,21043346 ! protein amino acid glycosylation GO:0006486 66 66 0,000 0,20684248 0,21320509 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! nucleoside triphosphate metabolic process GO:0009141 66 66 0,000 0,20684248 0,21308591 ! DNA packaging GO:0006323 66 66 0,000 0,20684248 0,21296687 ! polysaccharide metabolic process GO:0005976 69 66 0,000 0,20684248 0,21284796 ! negative regulation of protein metabolic process GO:0051248 66 66 0,000 0,20684248 0,21272918 ! cell morphogenesis involved in neuron differentiation GO:0048667 72 67 0,000 0,20963611 0,21548207 GO:0048812|neuron projection morphogenesis, GO:0048858|cell projection morphogenesis, ! Golgi vesicle transport GO:0048193 67 67 0,000 0,20963611 0,21536196 ! muscle contraction GO:0006936 67 67 0,000 0,20963611 0,21524198 ! negative regulation of cell differentiation GO:0045596 68 67 0,000 0,20963611 0,21512213 ! Ras protein signal transduction GO:0007265 69 67 0,000 0,20963611 0,21500242 ! purine ribonucleotide biosynthetic process GO:0009152 68 68 0,000 0,21242031 0,21773672 ! chromatin assembly or disassembly GO:0006333 68 68 0,000 0,21242031 0,21761569 ! regulation of cell size GO:0008361 68 68 0,000 0,21242031 0,21749479 ! regulation of translation GO:0006417 69 69 0,000 0,2151951 0,22021353 ! sensory perception of sound GO:0007605 71 69 0,000 0,2151951 0,22009133 GO:0050954|sensory perception of mechanical stimulus, ! regulation of leukocyte activation GO:0002694 69 69 0,000 0,2151951 0,21996926 ! positive regulation of transport GO:0051050 71 70 0,000 0,21796053 0,22267254 ! cell part morphogenesis GO:0032990 75 70 0,000 0,21796053 0,22254917 ! growth GO:0040007 70 70 0,000 0,21796053 0,22242594 ! carboxylic acid biosynthetic process GO:0046394 70 70 0,000 0,21796053 0,22230285 GO:0016053|organic acid biosynthetic process, ! translational elongation GO:0006414 71 71 0,000 0,22071661 0,22498934 ! oxidative phosphorylation GO:0006119 71 71 0,000 0,22071661 0,22486496 ! calcium ion homeostasis GO:0055074 71 71 0,000 0,22071661 0,22474073 GO:0006874|cellular calcium ion homeostasis, ! ribosome biogenesis GO:0042254 71 71 0,000 0,22071661 0,22461663 ! negative regulation of signal transduction GO:0009968 71 71 0,000 0,22071661 0,22449267 ! regulation of cell activation GO:0050865 71 71 0,000 0,22071661 0,22436885 ! secretion by cell GO:0032940 75 72 0,000 0,22346339 0,22703585 ! muscle system process GO:0003012 72 72 0,000 0,22346339 0,22691076 ! sensory organ development GO:0007423 72 72 0,000 0,22346339 0,22678581 ! electron transport chain GO:0022900 75 74 0,000 0,22892914 0,23220495 ! ribonucleotide biosynthetic process GO:0009260 75 75 0,000 0,23164816 0,23483364 ! purine ribonucleotide metabolic process GO:0009150 75 75 0,000 0,23164816 0,23470454 ! negative regulation of cell communication GO:0010648 76 76 0,000 0,234358 0,23731967 ! cellular metal ion homeostasis GO:0006875 77 77 0,000 0,23705868 0,23992265 ! microtubule-based movement GO:0007018 82 78 0,000 0,23975022 0,24251354 ! metal ion homeostasis GO:0055065 78 78 0,000 0,23975022 0,24238051 ! regulation of immune response GO:0050776 78 78 0,000 0,23975022 0,24224762 ! nuclear transport GO:0051169 79 79 0,000 0,24243267 0,24482379 GO:0006913|nucleocytoplasmic transport, ! glycoprotein biosynthetic process GO:0009101 80 80 0,000 0,24510604 0,24738797 ! neuron projection development GO:0031175 85 80 0,000 0,24510604 0,24725257 ! lymphocyte activation GO:0046649 82 81 0,000 0,24777037 0,2498035 ! lipid catabolic process GO:0016042 82 81 0,000 0,24777037 0,24966692 ! ribonucleotide metabolic process GO:0009259 83 83 0,000 0,25307203 0,25486981 ! ncRNA processing GO:0034470 83 83 0,000 0,25307203 0,25473061 ! regulation of cellular localization GO:0060341 86 85 0,000 0,25833786 0,25988902 ! nitrogen compound biosynthetic process GO:0044271 86 85 0,000 0,25833786 0,25974723 ! organophosphate metabolic process GO:0019637 87 86 0,000 0,26095742 0,26223802 GO:0006644|phospholipid metabolic process, ! male gamete generation GO:0048232 90 88 0,000 0,26616996 0,26733037 GO:0007283|spermatogenesis, ! purine nucleotide biosynthetic process GO:0006164 88 88 0,000 0,26616996 0,26718477 ! chemotaxis GO:0006935 90 89 0,000 0,268763 0,26964083 GO:0042330|taxis, ! visual perception GO:0007601 93 92 0,000 0,27648954 0,27724168 GO:0050953|sensory perception of light stimulus, ! tissue morphogenesis GO:0048729 94 93 0,000 0,27904762 0,27965457 ! regulation of response to stress GO:0080134 97 94 0,000 0,28159703 0,28205615 ! regulation of system process GO:0044057 98 98 0,000 0,29170855 0,29202545 ! anti-apoptosis GO:0006916 100 99 0,000 0,29421503 0,29437476 ! response to other organism GO:0051707 101 100 0,000 0,29671302 0,29671302