pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6808-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! branched chain family amino acid metabolic process GO:0009081 33 17 3,000 2,142E-07 5,154E-04 ! response to nutrient GO:0007584 125 82 5,000 2,423E-07 2,915E-04 ! positive regulation of glycolysis GO:0045821 14 5 2,000 3,027E-07 2,427E-04 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 3,000 4,33E-07 2,604E-04 ! nuclear migration GO:0007097 12 6 2,000 6,039E-07 2,906E-04 ! positive regulation of pseudopodium assembly GO:0031274 14 6 2,000 6,039E-07 2,422E-04 GO:0031272|regulation of pseudopodium assembly, ! regulation of oxidoreductase activity GO:0051341 46 24 3,000 9,404E-07 3,232E-04 ! positive regulation of cell migration GO:0030335 126 57 4,000 1,033E-06 3,105E-04 ! regulation of lipid kinase activity GO:0043550 13 7 2,000 1,054E-06 2,819E-04 ! macrophage differentiation GO:0030225 11 7 2,000 1,054E-06 2,537E-04 ! insulin receptor signaling pathway GO:0008286 64 26 3,000 1,317E-06 2,88E-04 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 3,000 1,317E-06 2,64E-04 ! establishment of nucleus localization GO:0040023 16 8 2,000 1,683E-06 3,115E-04 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 2,000 1,683E-06 2,893E-04 ! peptidyl-tyrosine modification GO:0018212 50 28 3,000 1,795E-06 2,879E-04 ! positive regulation of cell motion GO:0051272 146 64 4,000 1,848E-06 2,779E-04 ! positive regulation of glucose metabolic process GO:0010907 18 9 2,000 2,519E-06 3,565E-04 ! regulation of glycolysis GO:0006110 21 9 2,000 2,519E-06 3,367E-04 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 2,000 2,519E-06 3,19E-04 ! branched chain family amino acid catabolic process GO:0009083 17 9 2,000 2,519E-06 3,03E-04 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 2,000 3,59E-06 4,114E-04 GO:0043470|regulation of carbohydrate catabolic process, ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 2,000 3,59E-06 3,927E-04 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 2,000 4,926E-06 5,153E-04 ! positive regulation of endothelial cell proliferation GO:0001938 22 11 2,000 4,926E-06 4,938E-04 ! nucleus localization GO:0051647 19 11 2,000 4,926E-06 4,74E-04 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 3,000 5,064E-06 4,686E-04 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! cellular response to insulin stimulus GO:0032869 82 37 3,000 5,664E-06 5,048E-04 ! cellular response to hormone stimulus GO:0032870 167 82 4,000 6,323E-06 5,433E-04 ! positive regulation of cellular catabolic process GO:0031331 31 12 2,000 6,552E-06 5,436E-04 ! regulation of cell projection assembly GO:0060491 30 12 2,000 6,552E-06 5,255E-04 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 2,000 8,499E-06 6,596E-04 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of monooxygenase activity GO:0032768 33 13 2,000 8,499E-06 6,39E-04 ! ossification GO:0001503 188 90 4,000 9,984E-06 7,279E-04 ! bone development GO:0060348 189 91 4,000 1,054E-05 7,458E-04 ! interphase of mitotic cell cycle GO:0051329 209 95 4,000 1,3E-05 8,937E-04 ! response to cAMP GO:0051591 22 15 2,000 1,346E-05 8,995E-04 ! positive regulation of oxidoreductase activity GO:0051353 22 15 2,000 1,346E-05 8,752E-04 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 3,000 1,369E-05 8,671E-04 ! response to insulin stimulus GO:0032868 95 46 3,000 1,369E-05 8,449E-04 ! interphase GO:0051325 213 98 4,000 1,512E-05 9,097E-04 ! regulation of glucose metabolic process GO:0010906 28 16 2,000 1,653E-05 9,698E-04 ! filopodium assembly GO:0046847 32 16 2,000 1,653E-05 9,468E-04 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 2,000 2,002E-05 1,12E-03 ! microspike assembly GO:0030035 36 17 2,000 2,002E-05 1,095E-03 ! regulation of angiogenesis GO:0045765 114 52 3,000 2,239E-05 1,197E-03 ! response to retinoic acid GO:0032526 26 18 2,000 2,397E-05 1,254E-03 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 2,000 2,397E-05 1,227E-03 ! response to vitamin A GO:0033189 27 19 2,000 2,84E-05 1,424E-03 ! response to vitamin GO:0033273 31 20 2,000 3,334E-05 1,637E-03 ! regulation of carbohydrate metabolic process GO:0006109 38 20 2,000 3,334E-05 1,604E-03 GO:0010675|regulation of cellular carbohydrate metabolic process, ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 2,000 3,334E-05 1,573E-03 ! establishment of organelle localization GO:0051656 109 59 3,000 3,702E-05 1,713E-03 ! protein amino acid autophosphorylation GO:0046777 141 60 3,000 3,956E-05 1,796E-03 ! regulation of protein complex assembly GO:0043254 117 61 3,000 4,224E-05 1,882E-03 ! response to peptide hormone stimulus GO:0043434 122 61 3,000 4,224E-05 1,848E-03 ! response to glucocorticoid stimulus GO:0051384 38 22 2,000 4,483E-05 1,926E-03 ! myeloid leukocyte differentiation GO:0002573 40 23 2,000 5,144E-05 2,171E-03 ! regulation of cellular catabolic process GO:0031329 52 24 2,000 5,865E-05 2,433E-03 ! response to corticosteroid stimulus GO:0031960 41 24 2,000 5,865E-05 2,392E-03 ! vasculogenesis GO:0001570 46 25 2,000 6,649E-05 2,666E-03 ! osteoblast differentiation GO:0001649 60 25 2,000 6,649E-05 2,623E-03 ! interaction with host GO:0051701 62 25 2,000 6,649E-05 2,58E-03 ! acetyl-CoA metabolic process GO:0006084 39 26 2,000 7,5E-05 2,864E-03 ! regulation of endothelial cell proliferation GO:0001936 57 26 2,000 7,5E-05 2,819E-03 ! positive regulation of cell projection organization GO:0031346 58 27 2,000 8,418E-05 3,116E-03 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 2,000 8,418E-05 3,069E-03 ! organelle localization GO:0051640 136 74 3,000 9,026E-05 3,241E-03 ! cell-matrix adhesion GO:0007160 163 75 3,000 9,512E-05 3,365E-03 ! hemoglobin biosynthetic process GO:0042541 7 5 1,000 9,785E-05 3,412E-03 ! negative regulation of bone resorption GO:0045779 10 5 1,000 9,785E-05 3,363E-03 ! 2-oxoglutarate metabolic process GO:0006103 7 5 1,000 9,785E-05 3,316E-03 ! valine metabolic process GO:0006573 10 5 1,000 9,785E-05 3,27E-03 ! mRNA transcription GO:0009299 9 5 1,000 9,785E-05 3,225E-03 ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 9,785E-05 3,181E-03 ! peptidyl-histidine phosphorylation GO:0018106 9 5 1,000 9,785E-05 3,139E-03 ! meiotic chromosome segregation GO:0045132 7 5 1,000 9,785E-05 3,098E-03 ! positive regulation of chemokine production GO:0032722 8 5 1,000 9,785E-05 3,057E-03 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 1,000 9,785E-05 3,018E-03 ! negative regulation of protein complex assembly GO:0031333 59 29 2,000 1,047E-04 3,188E-03 ! cell junction assembly GO:0034329 78 30 2,000 1,16E-04 3,49E-03 ! regulation of adenylate cyclase activity GO:0045761 156 80 3,000 1,223E-04 3,632E-03 ! response to hypoxia GO:0001666 171 81 3,000 1,283E-04 3,765E-03 ! cell-substrate adhesion GO:0031589 171 81 3,000 1,283E-04 3,72E-03 ! regulation of cAMP biosynthetic process GO:0030817 161 82 3,000 1,346E-04 3,855E-03 ! regulation of cyclase activity GO:0031279 159 82 3,000 1,346E-04 3,81E-03 ! response to oxygen levels GO:0070482 176 83 3,000 1,411E-04 3,947E-03 ! regulation of lyase activity GO:0051339 160 83 3,000 1,411E-04 3,901E-03 ! positive regulation of catabolic process GO:0009896 64 32 2,000 1,411E-04 3,858E-03 ! regulation of hormone biosynthetic process GO:0046885 10 6 1,000 1,465E-04 3,96E-03 ! embryonic hemopoiesis GO:0035162 14 6 1,000 1,465E-04 3,916E-03 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 1,000 1,465E-04 3,873E-03 ! male sex determination GO:0030238 15 6 1,000 1,465E-04 3,831E-03 ! establishment of spindle localization GO:0051293 12 6 1,000 1,465E-04 3,789E-03 GO:0051653|spindle localization, ! regulation of cAMP metabolic process GO:0030814 168 84 3,000 1,478E-04 3,782E-03 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 3,000 1,692E-04 4,286E-03 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 2,000 1,695E-04 4,248E-03 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 3,000 1,929E-04 4,784E-03 ! cell junction organization GO:0034330 86 36 2,000 2,013E-04 4,942E-03 ! N-terminal protein amino acid acetylation GO:0006474 13 7 1,000 2,046E-04 4,973E-03 ! mRNA stabilization GO:0048255 18 7 1,000 2,046E-04 4,924E-03 GO:0043489|RNA stabilization, ! oxaloacetate metabolic process GO:0006107 10 7 1,000 2,046E-04 4,875E-03 ! positive regulation of monooxygenase activity GO:0032770 12 7 1,000 2,046E-04 4,827E-03 ! oxygen homeostasis GO:0032364 12 7 1,000 2,046E-04 4,78E-03 ! regulation of respiratory burst GO:0060263 11 7 1,000 2,046E-04 4,734E-03 ! peptidyl-histidine modification GO:0018202 16 7 1,000 2,046E-04 4,689E-03 ! establishment or maintenance of cell polarity GO:0007163 83 37 2,000 2,186E-04 4,961E-03 ! tissue remodeling GO:0048771 76 37 2,000 2,186E-04 4,914E-03 ! positive regulation of MAP kinase activity GO:0043406 160 93 3,000 2,188E-04 4,875E-03 ! regulation of nucleotide metabolic process GO:0006140 182 93 3,000 2,188E-04 4,83E-03 ! carbohydrate homeostasis GO:0033500 53 38 2,000 2,367E-04 5,178E-03 GO:0042593|glucose homeostasis, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 2,723E-04 5,902E-03 ! succinate metabolic process GO:0006105 14 8 1,000 2,723E-04 5,849E-03 ! T-helper 1 type immune response GO:0042088 12 8 1,000 2,723E-04 5,798E-03 ! hemoglobin metabolic process GO:0020027 13 8 1,000 2,723E-04 5,747E-03 ! positive regulation of endothelial cell migration GO:0010595 19 8 1,000 2,723E-04 5,697E-03 ! regulation of vascular permeability GO:0043114 12 8 1,000 2,723E-04 5,648E-03 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 1,000 2,723E-04 5,599E-03 ! multicellular organismal metabolic process GO:0044236 57 40 2,000 2,76E-04 5,628E-03 ! cytokinesis GO:0000910 72 40 2,000 2,76E-04 5,58E-03 ! neuron migration GO:0001764 79 42 2,000 3,192E-04 6,401E-03 ! regulation of developmental growth GO:0048638 15 9 1,000 3,494E-04 6,947E-03 ! induction of positive chemotaxis GO:0050930 15 9 1,000 3,494E-04 6,89E-03 ! phosphagen metabolic process GO:0006599 12 9 1,000 3,494E-04 6,834E-03 GO:0006600|creatine metabolic process, ! protein heterooligomerization GO:0051291 16 9 1,000 3,494E-04 6,779E-03 ! gas homeostasis GO:0033483 16 9 1,000 3,494E-04 6,725E-03 ! S phase GO:0051320 9 9 1,000 3,494E-04 6,671E-03 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 1,000 3,494E-04 6,619E-03 ! glycolysis GO:0006096 65 45 2,000 3,919E-04 7,367E-03 ! induction of apoptosis by intracellular signals GO:0008629 93 45 2,000 3,919E-04 7,31E-03 ! regulation of gene-specific transcription GO:0032583 96 46 2,000 4,183E-04 7,742E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 1,000 4,358E-04 8,004E-03 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 4,358E-04 7,944E-03 ! lung alveolus development GO:0048286 26 10 1,000 4,358E-04 7,884E-03 ! negative regulation of striated muscle development GO:0045843 19 10 1,000 4,358E-04 7,825E-03 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 1,000 4,358E-04 7,767E-03 ! regulation of bone resorption GO:0045124 25 10 1,000 4,358E-04 7,71E-03 ! positive regulation of leukocyte migration GO:0002687 25 10 1,000 4,358E-04 7,654E-03 ! localization within membrane GO:0051668 20 10 1,000 4,358E-04 7,598E-03 ! positive regulation of cell cycle GO:0045787 89 48 2,000 4,744E-04 8,212E-03 ! negative regulation of muscle development GO:0048635 20 11 1,000 5,316E-04 9,135E-03 ! blood vessel remodeling GO:0001974 29 11 1,000 5,316E-04 9,071E-03 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 1,000 5,316E-04 9,007E-03 GO:0010812|negative regulation of cell-substrate adhesion, ! peptide or protein amino-terminal blocking GO:0018409 21 11 1,000 5,316E-04 8,944E-03 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 1,000 5,316E-04 8,882E-03 ! regulation of leukocyte migration GO:0002685 26 11 1,000 5,316E-04 8,82E-03 ! regulation of embryonic development GO:0045995 27 11 1,000 5,316E-04 8,76E-03 ! regulation of cell projection organization GO:0031344 121 50 2,000 5,352E-04 8,76E-03 ! regulation of cell shape GO:0008360 125 51 2,000 5,674E-04 9,223E-03 ! positive regulation of growth GO:0045927 90 52 2,000 6,007E-04 9,7E-03 ! cartilage development GO:0051216 90 52 2,000 6,007E-04 9,635E-03 ! response to UV GO:0009411 104 53 2,000 6,353E-04 0,01012288 ! virus-host interaction GO:0019048 29 12 1,000 6,366E-04 0,01007622 ! regulation of B cell proliferation GO:0030888 20 12 1,000 6,366E-04 0,01001036 ! cartilage condensation GO:0001502 20 12 1,000 6,366E-04 9,945E-03 ! regulation of positive chemotaxis GO:0050926 19 12 1,000 6,366E-04 9,881E-03 GO:0050927|positive regulation of positive chemotaxis, ! focal adhesion formation GO:0048041 35 12 1,000 6,366E-04 9,818E-03 ! entry into host cell GO:0030260 32 12 1,000 6,366E-04 9,755E-03 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! histone acetylation GO:0016573 26 12 1,000 6,366E-04 9,694E-03 ! regulation of hormone metabolic process GO:0032350 26 12 1,000 6,366E-04 9,633E-03 ! peptidyl-lysine modification GO:0018205 21 12 1,000 6,366E-04 9,572E-03 ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 1,000 6,366E-04 9,513E-03 ! glucose catabolic process GO:0006007 82 55 2,000 7,083E-04 0,01051888 ! heart morphogenesis GO:0003007 97 55 2,000 7,083E-04 0,01045434 ! regulation of chemokine production GO:0032642 18 13 1,000 7,508E-04 0,01101425 ! cell-cell junction assembly GO:0007043 27 13 1,000 7,508E-04 0,0109475 ! cellular carbohydrate catabolic process GO:0044275 15 13 1,000 7,508E-04 0,01088155 ! regulation of mRNA stability GO:0043488 31 13 1,000 7,508E-04 0,01081639 ! embryonic placenta development GO:0001892 23 13 1,000 7,508E-04 0,01075201 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 2,000 7,863E-04 0,01119469 ! N-terminal protein amino acid modification GO:0031365 27 14 1,000 8,741E-04 0,01237097 ! regulation of erythrocyte differentiation GO:0045646 44 14 1,000 8,741E-04 0,01229863 ! regulation of RNA stability GO:0043487 32 14 1,000 8,741E-04 0,01222713 ! DNA damage response, signal transduction GO:0042770 128 60 2,000 9,134E-04 0,01270255 ! viral reproductive process GO:0022415 126 62 2,000 1,005E-03 0,01389478 ! regulation of homeostatic process GO:0032844 134 62 2,000 1,005E-03 0,01381538 ! negative regulation of bone remodeling GO:0046851 33 15 1,000 1,006E-03 0,01375928 ! muscle maintenance GO:0046716 26 15 1,000 1,006E-03 0,01368154 ! epithelial to mesenchymal transition GO:0001837 28 15 1,000 1,006E-03 0,01360468 ! regulation of lipid metabolic process GO:0019216 115 63 2,000 1,053E-03 0,01414974 ! cellular amino acid catabolic process GO:0009063 101 63 2,000 1,053E-03 0,01407113 ! embryonic forelimb morphogenesis GO:0035115 28 16 1,000 1,148E-03 0,01525911 ! negative regulation of tissue remodeling GO:0034104 36 16 1,000 1,148E-03 0,01517527 ! myeloid cell differentiation GO:0030099 111 65 2,000 1,153E-03 0,01515463 ! cell projection assembly GO:0030031 120 66 2,000 1,205E-03 0,01575411 ! activation of MAPK activity GO:0000187 115 67 2,000 1,258E-03 0,01636615 ! hexose catabolic process GO:0019320 104 67 2,000 1,258E-03 0,01627816 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 2,000 1,258E-03 0,01619111 ! negative regulation of protein kinase activity GO:0006469 130 67 2,000 1,258E-03 0,01610499 ! lung development GO:0030324 144 67 2,000 1,258E-03 0,01601978 ! negative regulation of cell cycle process GO:0010948 32 17 1,000 1,298E-03 0,01644068 ! heart looping GO:0001947 30 17 1,000 1,298E-03 0,0163546 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 1,000 1,298E-03 0,01626942 ! neural crest cell migration GO:0001755 37 17 1,000 1,298E-03 0,01618513 ! negative regulation of homeostatic process GO:0032845 33 17 1,000 1,298E-03 0,0161017 ! negative regulation of kinase activity GO:0033673 131 68 2,000 1,314E-03 0,01620658 ! viral reproduction GO:0016032 134 68 2,000 1,314E-03 0,01612389 ! respiratory tube development GO:0030323 150 70 2,000 1,428E-03 0,01744265 ! positive regulation of anti-apoptosis GO:0045768 39 18 1,000 1,458E-03 0,01771205 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 1,458E-03 0,01762305 ! cell-substrate junction assembly GO:0007044 54 18 1,000 1,458E-03 0,01753493 ! amine catabolic process GO:0009310 117 71 2,000 1,488E-03 0,01780921 ! negative regulation of transferase activity GO:0051348 140 72 2,000 1,549E-03 0,01844953 ! respiratory system development GO:0060541 153 72 2,000 1,549E-03 0,01835864 ! positive regulation of angiogenesis GO:0045766 44 19 1,000 1,626E-03 0,01917418 ! lipid phosphorylation GO:0046834 35 19 1,000 1,626E-03 0,01908065 ! forelimb morphogenesis GO:0035136 32 19 1,000 1,626E-03 0,01898803 ! actin filament bundle formation GO:0051017 42 19 1,000 1,626E-03 0,0188963 ! plasma membrane fusion GO:0045026 28 19 1,000 1,626E-03 0,01880545 ! regulation of endothelial cell migration GO:0010594 44 19 1,000 1,626E-03 0,01871547 ! cell-cell junction organization GO:0045216 35 19 1,000 1,626E-03 0,01862635 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 1,000 1,626E-03 0,01853807 ! protein amino acid acetylation GO:0006473 39 20 1,000 1,803E-03 0,02045866 ! negative regulation of angiogenesis GO:0016525 45 20 1,000 1,803E-03 0,02036261 ! monosaccharide catabolic process GO:0046365 115 76 2,000 1,809E-03 0,02034193 ! regulation of catabolic process GO:0009894 161 76 2,000 1,809E-03 0,02024731 ! response to steroid hormone stimulus GO:0048545 137 78 2,000 1,949E-03 0,02171056 ! hindlimb morphogenesis GO:0035137 43 21 1,000 1,988E-03 0,0220459 ! positive regulation of locomotion GO:0040017 39 21 1,000 1,988E-03 0,02194477 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! positive regulation of phosphorylation GO:0042327 129 79 2,000 2,021E-03 0,02220791 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 2,000 2,171E-03 0,02374358 GO:0045937|positive regulation of phosphate metabolic process, ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 1,000 2,183E-03 0,02376276 ! regulation of chemotaxis GO:0050920 40 22 1,000 2,183E-03 0,02365572 ! calcium-independent cell-cell adhesion GO:0016338 30 22 1,000 2,183E-03 0,02354964 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 1,000 2,183E-03 0,02344451 ! positive regulation of B cell activation GO:0050871 38 22 1,000 2,183E-03 0,02334031 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 1,000 2,183E-03 0,02323703 ! positive regulation of DNA replication GO:0045740 43 23 1,000 2,386E-03 0,02528605 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 1,000 2,386E-03 0,02517515 ! regulation of anti-apoptosis GO:0045767 53 23 1,000 2,386E-03 0,02506521 ! regulation of cell-matrix adhesion GO:0001952 78 23 1,000 2,386E-03 0,02495623 GO:0010810|regulation of cell-substrate adhesion, ! sex determination GO:0007530 47 23 1,000 2,386E-03 0,0248482 ! acetyl-CoA catabolic process GO:0046356 36 23 1,000 2,386E-03 0,02474109 GO:0006099|tricarboxylic acid cycle, ! negative regulation of growth GO:0045926 155 84 2,000 2,408E-03 0,02486705 ! alcohol catabolic process GO:0046164 130 86 2,000 2,575E-03 0,02647393 ! positive regulation of fibroblast proliferation GO:0048146 43 24 1,000 2,597E-03 0,02659114 ! regulation of behavior GO:0050795 43 24 1,000 2,597E-03 0,02647846 ! negative regulation of phosphorylation GO:0042326 47 24 1,000 2,597E-03 0,02636674 ! protein tetramerization GO:0051262 52 24 1,000 2,597E-03 0,02625596 ! nitrogen compound catabolic process GO:0044270 143 87 2,000 2,661E-03 0,02678496 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 1,000 2,817E-03 0,02824329 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 1,000 2,817E-03 0,0281261 ! dicarboxylic acid metabolic process GO:0043648 42 25 1,000 2,817E-03 0,02800988 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 1,000 2,817E-03 0,02789461 ! neural crest cell development GO:0014032 54 25 1,000 2,817E-03 0,02778029 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 1,000 2,817E-03 0,0276669 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 1,000 2,817E-03 0,02755443 ! somitogenesis GO:0001756 43 25 1,000 2,817E-03 0,02744287 ! neural tube closure GO:0001843 49 25 1,000 2,817E-03 0,02733222 GO:0060606|tube closure, ! regulation of cell morphogenesis GO:0022604 215 89 2,000 2,838E-03 0,02742044 ! initiation of viral infection GO:0019059 57 26 1,000 3,046E-03 0,02931288 ! pyruvate metabolic process GO:0006090 38 26 1,000 3,046E-03 0,02919609 ! tube lumen formation GO:0035148 50 26 1,000 3,046E-03 0,02908023 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 1,000 3,046E-03 0,02896529 GO:0045936|negative regulation of phosphate metabolic process, ! cellular response to oxidative stress GO:0034599 39 26 1,000 3,046E-03 0,02885126 ! positive regulation of nuclear division GO:0051785 40 26 1,000 3,046E-03 0,02873811 GO:0045840|positive regulation of mitosis, ! regulation of fibroblast proliferation GO:0048145 52 27 1,000 3,283E-03 0,03085263 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 1,000 3,283E-03 0,03073258 ! protein amino acid acylation GO:0043543 55 27 1,000 3,283E-03 0,03061347 ! primary neural tube formation GO:0014020 51 27 1,000 3,283E-03 0,03049527 ! regulation of chromosome organization GO:0033044 42 27 1,000 3,283E-03 0,03037798 ! regulation of Rho protein signal transduction GO:0035023 213 95 2,000 3,412E-03 0,03145339 ! leukocyte differentiation GO:0002521 202 96 2,000 3,514E-03 0,03227088 ! carboxylic acid catabolic process GO:0046395 156 98 2,000 3,724E-03 0,03406706 GO:0016054|organic acid catabolic process, ! cellular iron ion homeostasis GO:0006879 51 29 1,000 3,782E-03 0,03446417 ! cellular response to extracellular stimulus GO:0031668 48 29 1,000 3,782E-03 0,03433412 ! negative regulation of neuron apoptosis GO:0043524 56 29 1,000 3,782E-03 0,03420504 ! positive regulation of multicellular organism growth GO:0040018 51 30 1,000 4,043E-03 0,03643631 ! cofactor catabolic process GO:0051187 51 30 1,000 4,043E-03 0,03630035 ! regulation of B cell activation GO:0050864 50 30 1,000 4,043E-03 0,03616541 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 1,000 4,313E-03 0,03843761 ! collagen metabolic process GO:0032963 45 31 1,000 4,313E-03 0,03829578 ! iron ion homeostasis GO:0055072 54 31 1,000 4,313E-03 0,03815498 ! spindle organization GO:0007051 46 32 1,000 4,592E-03 0,04046666 ! DNA damage checkpoint GO:0000077 71 33 1,000 4,878E-03 0,04283245 ! positive regulation of gene-specific transcription GO:0043193 65 33 1,000 4,878E-03 0,0426767 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 1,000 5,172E-03 0,04508736 ! regulation of striated muscle tissue development GO:0016202 69 34 1,000 5,172E-03 0,04492459 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 1,000 5,172E-03 0,044763 ! mismatch repair GO:0006298 46 34 1,000 5,172E-03 0,04460255 ! placenta development GO:0001890 53 34 1,000 5,172E-03 0,04444326 ! regulation of muscle development GO:0048634 70 35 1,000 5,474E-03 0,04687307 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 1,000 5,474E-03 0,04670686 ! negative regulation of cell adhesion GO:0007162 81 35 1,000 5,474E-03 0,04654181 ! calcium-mediated signaling GO:0019722 62 35 1,000 5,474E-03 0,04637793 ! neural tube formation GO:0001841 67 35 1,000 5,474E-03 0,0462152 ! mitotic sister chromatid segregation GO:0000070 57 36 1,000 5,785E-03 0,04866304 ! positive regulation of JAK-STAT cascade GO:0046427 50 36 1,000 5,785E-03 0,04849348 ! DNA integrity checkpoint GO:0031570 75 36 1,000 5,785E-03 0,0483251 ! aerobic respiration GO:0009060 55 36 1,000 5,785E-03 0,04815788 ! embryonic organ development GO:0048568 57 36 1,000 5,785E-03 0,04799182 ! meiosis I GO:0007127 65 37 1,000 6,103E-03 0,05045661 ! sister chromatid segregation GO:0000819 58 37 1,000 6,103E-03 0,05028381 ! positive regulation of DNA metabolic process GO:0051054 72 38 1,000 6,428E-03 0,0527882 ! mitotic cell cycle checkpoint GO:0007093 76 38 1,000 6,428E-03 0,05260865 ! embryonic epithelial tube formation GO:0001838 72 38 1,000 6,428E-03 0,05243032 ! positive regulation of leukocyte proliferation GO:0070665 62 38 1,000 6,428E-03 0,05225319 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! segmentation GO:0035282 67 39 1,000 6,762E-03 0,05478018 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 1,000 7,104E-03 0,05735256 ! mesenchymal cell development GO:0014031 87 40 1,000 7,104E-03 0,05716075 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! cellular amide metabolic process GO:0043603 67 41 1,000 7,453E-03 0,05976956 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 1,000 7,453E-03 0,05957099 ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 7,809E-03 0,06221525 GO:0090047|positive regulation of transcription regulator activity, ! regulation of myeloid cell differentiation GO:0045637 98 42 1,000 7,809E-03 0,06200992 ! glucose transport GO:0015758 65 43 1,000 8,173E-03 0,06468867 ! positive regulation of response to external stimulus GO:0032103 77 43 1,000 8,173E-03 0,06447658 ! neural tube development GO:0021915 77 43 1,000 8,173E-03 0,06426587 ! regulation of epithelial cell proliferation GO:0050678 111 43 1,000 8,173E-03 0,06405654 ! hexose transport GO:0008645 67 44 1,000 8,545E-03 0,06675259 GO:0015749|monosaccharide transport, ! JAK-STAT cascade GO:0007259 71 44 1,000 8,545E-03 0,06653656 ! regulation of actin filament polymerization GO:0030833 87 45 1,000 8,924E-03 0,06926519 ! regulation of JAK-STAT cascade GO:0046425 70 45 1,000 8,924E-03 0,06904247 ! negative regulation of cell migration GO:0030336 115 46 1,000 9,311E-03 0,07180279 ! positive regulation of DNA binding GO:0043388 73 47 1,000 9,705E-03 0,07460212 ! vascular process in circulatory system GO:0003018 80 47 1,000 9,705E-03 0,07436454 ! morphogenesis of embryonic epithelium GO:0016331 91 48 1,000 0,01010643 0,07719388 ! regulation of mast cell proliferation GO:0070666 81 48 1,000 0,01010643 0,07694959 ! histone modification GO:0016570 91 50 1,000 0,01093086 0,0829642 ! positive regulation of cytokine production GO:0001819 86 50 1,000 0,01093086 0,08270331 ! positive regulation of binding GO:0051099 78 51 1,000 0,01135386 0,08563445 ! viral infectious cycle GO:0019058 99 51 1,000 0,01135386 0,08536685 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 1,000 0,01135386 0,08510091 ! regulation of leukocyte proliferation GO:0070663 88 51 1,000 0,01135386 0,08483662 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! epithelial tube morphogenesis GO:0060562 98 51 1,000 0,01135386 0,08457397 ! membrane fusion GO:0006944 110 52 1,000 0,01178399 0,08750702 ! covalent chromatin modification GO:0016569 101 52 1,000 0,01178399 0,08723777 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 1,000 0,01222119 0,09019688 ! regulation of neuron apoptosis GO:0043523 100 53 1,000 0,01222119 0,08992105 ! regulation of protein polymerization GO:0032271 103 53 1,000 0,01222119 0,0896469 ! activation of phospholipase C activity GO:0007202 103 54 1,000 0,01266542 0,09262312 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of phospholipase activity GO:0010518 104 55 1,000 0,01311664 0,09563221 ! regulation of multicellular organism growth GO:0040014 85 55 1,000 0,01311664 0,09534329 ! negative regulation of cell motion GO:0051271 134 55 1,000 0,01311664 0,09505611 ! regulation of actin filament length GO:0030832 105 56 1,000 0,01357478 0,09808088 ! regulation of DNA replication GO:0006275 101 56 1,000 0,01357478 0,09778722 ! positive regulation of organelle organization GO:0010638 100 56 1,000 0,01357478 0,09749532 ! regulation of bone remodeling GO:0046850 137 57 1,000 0,01403982 0,10053514 ! lipid modification GO:0030258 97 57 1,000 0,01403982 0,10023681 ! regulation of phospholipase activity GO:0010517 106 57 1,000 0,01403982 0,09994025 ! regulation of tissue remodeling GO:0034103 140 58 1,000 0,01451169 0,1029945 ! positive regulation of lipase activity GO:0060193 108 58 1,000 0,01451169 0,10269158 ! regulation of cellular component size GO:0032535 109 59 1,000 0,01499036 0,10576777 ! skeletal system morphogenesis GO:0048705 105 59 1,000 0,01499036 0,10545851 ! integrin-mediated signaling pathway GO:0007229 135 59 1,000 0,01499036 0,10515105 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,01567367 0,10962457 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,01567367 0,10930682 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,01567367 0,1089909 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,01567367 0,10867681 ! neuron fate determination GO:0048664 7 5 0,000 0,01567367 0,10836452 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01567367 0,10805402 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,01567367 0,10774529 ! polyol transport GO:0015791 12 5 0,000 0,01567367 0,10743832 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,01567367 0,1071331 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,01567367 0,10682961 ! response to superoxide GO:0000303 10 5 0,000 0,01567367 0,10652783 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,01567367 0,10622775 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,01567367 0,10592936 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,01567367 0,10563264 ! female meiosis GO:0007143 7 5 0,000 0,01567367 0,10533757 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,01567367 0,10504416 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,01567367 0,10475237 ! cobalt ion transport GO:0006824 11 5 0,000 0,01567367 0,10446219 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,01567367 0,10417362 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,01567367 0,10388664 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,01567367 0,10360124 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,01567367 0,1033174 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,01567367 0,10303511 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,01567367 0,10275436 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,01567367 0,10247514 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,01567367 0,10219743 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,01567367 0,10192122 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,01567367 0,1016465 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01567367 0,10137326 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,01567367 0,10110148 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 0,01567367 0,10083115 ! negative chemotaxis GO:0050919 14 5 0,000 0,01567367 0,10056227 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,01567367 0,10029482 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,01567367 0,10002878 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,01567367 0,09976416 ! behavioral response to pain GO:0048266 9 5 0,000 0,01567367 0,09950093 ! clathrin coat assembly GO:0048268 14 5 0,000 0,01567367 0,09923908 ! Notch receptor processing GO:0007220 8 5 0,000 0,01567367 0,09897861 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01567367 0,09871951 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,01567367 0,09846175 ! micturition GO:0060073 9 5 0,000 0,01567367 0,09820534 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,01567367 0,09795026 ! copulation GO:0007620 9 5 0,000 0,01567367 0,09769651 ! glial cell fate commitment GO:0021781 13 5 0,000 0,01567367 0,09744406 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,01567367 0,09719292 ! spermidine metabolic process GO:0008216 7 5 0,000 0,01567367 0,09694306 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,01567367 0,09669449 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,01567367 0,09644719 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,01567367 0,09620115 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,01567367 0,09595637 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,01567367 0,09571282 ! grooming behavior GO:0007625 6 5 0,000 0,01567367 0,09547051 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,01567367 0,09522942 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,01567367 0,09498955 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01567367 0,09475088 ! response to protozoan GO:0001562 10 5 0,000 0,01567367 0,09451341 ! lymph vessel development GO:0001945 10 5 0,000 0,01567367 0,09427713 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,01567367 0,09404202 ! endochondral ossification GO:0001958 16 5 0,000 0,01567367 0,09380809 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,01567367 0,09357531 ! parathyroid gland development GO:0060017 13 5 0,000 0,01567367 0,09334369 ! anagen GO:0042640 6 5 0,000 0,01567367 0,09311321 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,01567367 0,09288387 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,01567367 0,09265566 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,01567367 0,09242856 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,01567367 0,09220257 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,01567367 0,09197769 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,01567367 0,0917539 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,01567367 0,09153119 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,01567367 0,09130957 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,01567367 0,09108901 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,01567367 0,09086952 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,01567367 0,09065109 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,01567367 0,0904337 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,01567367 0,09021735 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,01567367 0,09000203 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,01567367 0,08978774 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,01567367 0,08957447 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 0,01567367 0,08936221 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,01567367 0,08915095 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,01567367 0,08894069 ! histidine catabolic process GO:0006548 6 5 0,000 0,01567367 0,08873142 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,01567367 0,08852313 ! microvillus organization GO:0032528 7 5 0,000 0,01567367 0,08831581 GO:0030033|microvillus assembly, ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,01567367 0,08810947 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,01567367 0,08790408 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,01567367 0,08769966 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,01567367 0,08749618 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,01567367 0,08729364 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,01567367 0,08709204 ! polyol catabolic process GO:0046174 7 5 0,000 0,01567367 0,08689136 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,01567367 0,08669161 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,01567367 0,08649278 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,01567367 0,08629486 ! muscle cell migration GO:0014812 8 5 0,000 0,01567367 0,08609784 ! mitochondrial fission GO:0000266 8 5 0,000 0,01567367 0,08590171 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,01567367 0,08570648 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,01567367 0,08551214 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,01567367 0,08531867 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,01567367 0,08512608 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,01567367 0,08493435 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,01567367 0,08474349 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,01567367 0,08455348 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,01567367 0,08436432 ! response to food GO:0032094 6 5 0,000 0,01567367 0,08417601 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,01567367 0,08398853 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,01567367 0,08380189 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,01567367 0,08361608 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01567367 0,08343109 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,01567367 0,08324691 ! forebrain neuron development GO:0021884 13 5 0,000 0,01567367 0,08306355 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,01567367 0,08288099 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,01567367 0,08269924 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,01567367 0,08251828 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01567367 0,0823381 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,01567367 0,08215872 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01567367 0,08198011 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,01567367 0,08180228 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,01567367 0,08162522 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,01567367 0,08144892 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,01567367 0,08127339 ! basic amino acid transport GO:0015802 11 5 0,000 0,01567367 0,08109861 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,01567367 0,08092457 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,01567367 0,08075129 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01567367 0,08057874 ! depyrimidination GO:0045008 10 5 0,000 0,01567367 0,08040693 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,01567367 0,08023585 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01567367 0,0800655 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,01567367 0,07989587 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,01567367 0,07972696 GO:0006882|cellular zinc ion homeostasis, ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,01567367 0,07955876 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01567367 0,07939127 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,01567367 0,07922448 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,01567367 0,07905839 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,01567367 0,078893 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,01567367 0,07872829 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,01567367 0,07856427 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01567367 0,07840094 ! response to arsenic GO:0046685 10 5 0,000 0,01567367 0,07823828 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,01567367 0,0780763 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,01567367 0,07791498 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,01567367 0,07775433 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,01567367 0,07759435 ! response to cadmium ion GO:0046686 7 5 0,000 0,01567367 0,07743501 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,01567367 0,07727634 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,01567367 0,07711831 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,01567367 0,07696092 ! decidualization GO:0046697 11 5 0,000 0,01567367 0,07680418 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,01567367 0,07664807 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,01567367 0,0764926 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,01567367 0,07633776 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,01567367 0,07618354 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,01567367 0,07602994 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,01567367 0,07587697 ! neural tube patterning GO:0021532 7 5 0,000 0,01567367 0,0757246 ! embryonic cleavage GO:0040016 6 5 0,000 0,01567367 0,07557285 ! peroxisome fission GO:0016559 5 5 0,000 0,01567367 0,0754217 ! histone demethylation GO:0016577 10 5 0,000 0,01567367 0,07527116 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,01567367 0,07512122 ! mitotic recombination GO:0006312 9 5 0,000 0,01567367 0,07497187 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,01567367 0,07482312 ! metaphase plate congression GO:0051310 7 5 0,000 0,01567367 0,07467495 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01567367 0,07452738 GO:0032374|regulation of cholesterol transport, ! enteric nervous system development GO:0048484 8 5 0,000 0,01567367 0,07438038 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,01567367 0,07423396 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,01567367 0,07408812 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,01567367 0,07394285 ! muscle cell proliferation GO:0033002 11 5 0,000 0,01567367 0,07379814 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,01567367 0,07365401 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,01567367 0,07351043 ! plasminogen activation GO:0031639 5 5 0,000 0,01567367 0,07336742 ! B cell homeostasis GO:0001782 13 5 0,000 0,01567367 0,07322495 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,01567367 0,07308305 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,01567367 0,07294169 ! metaphase GO:0051323 8 5 0,000 0,01567367 0,07280087 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,01567367 0,0726606 ! cellular response to nutrient GO:0031670 8 5 0,000 0,01567367 0,07252087 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,01567367 0,07238167 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,01567367 0,07224301 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,01567367 0,07210488 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,01567367 0,07196727 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,01567367 0,07183019 ! response to redox state GO:0051775 5 5 0,000 0,01567367 0,07169363 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,01567367 0,07155759 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,01567367 0,07142207 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,01567367 0,07128705 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,01567367 0,07115255 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01567367 0,07101855 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,01567367 0,07088506 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01567367 0,07075207 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,01567367 0,07061957 ! striatum development GO:0021756 9 5 0,000 0,01567367 0,07048757 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,01567367 0,07035607 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,01567367 0,07022505 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,01567367 0,07009452 ! glial cell migration GO:0008347 11 5 0,000 0,01567367 0,06996447 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,01567367 0,06983491 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,01567367 0,06970583 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,01567367 0,06957722 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,01567367 0,06944908 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,01567367 0,06932142 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,01567367 0,06919422 ! neuroprotection GO:0043526 6 5 0,000 0,01567367 0,06906749 ! neural plate development GO:0001840 8 5 0,000 0,01567367 0,06894123 ! regulation of sensory perception GO:0051931 7 5 0,000 0,01567367 0,06881542 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,01567367 0,06869008 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,01567367 0,06856519 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,01567367 0,06844075 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,01567367 0,06831676 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,01567367 0,06819322 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,01567367 0,06807013 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,01567367 0,06794748 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,01567367 0,06782527 ! spindle assembly GO:0051225 6 5 0,000 0,01567367 0,0677035 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,01567367 0,06758217 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,01567367 0,06746127 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,01567367 0,06734081 ! drug metabolic process GO:0017144 6 5 0,000 0,01567367 0,06722077 ! stem cell division GO:0017145 11 5 0,000 0,01567367 0,06710116 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,01567367 0,06698197 ! organ regeneration GO:0031100 7 5 0,000 0,01567367 0,06686321 ! carnitine metabolic process GO:0009437 7 5 0,000 0,01567367 0,06674487 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,01567367 0,06662695 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,01567367 0,06650944 ! mesoderm development GO:0007498 119 61 1,000 0,01596789 0,06763863 ! regulation of mitosis GO:0007088 105 63 1,000 0,01697203 0,07176575 GO:0051783|regulation of nuclear division, ! embryonic limb morphogenesis GO:0030326 125 65 1,000 0,01800242 0,07598918 GO:0035113|embryonic appendage morphogenesis, ! actin filament organization GO:0007015 148 66 1,000 0,01852735 0,07806796 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,01877911 0,07899045 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,01877911 0,0788526 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,01877911 0,07871523 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,01877911 0,07857833 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,01877911 0,07844191 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,01877911 0,07830596 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,01877911 0,07817048 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,01877911 0,07803547 ! sleep GO:0030431 13 6 0,000 0,01877911 0,07790093 ! response to oxygen radical GO:0000305 11 6 0,000 0,01877911 0,07776685 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,01877911 0,07763323 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,01877911 0,07750007 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,01877911 0,07736736 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,01877911 0,07723511 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,01877911 0,07710331 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,01877911 0,07697196 ! forebrain regionalization GO:0021871 8 6 0,000 0,01877911 0,07684105 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,01877911 0,07671059 ! male meiosis GO:0007140 7 6 0,000 0,01877911 0,07658058 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,01877911 0,076451 ! response to zinc ion GO:0010043 9 6 0,000 0,01877911 0,07632186 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,01877911 0,07619315 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,01877911 0,07606488 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,01877911 0,07593704 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,01877911 0,07580963 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,01877911 0,07568265 ! malate metabolic process GO:0006108 11 6 0,000 0,01877911 0,07555609 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,01877911 0,07542995 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,01877911 0,07530423 ! protein refolding GO:0042026 15 6 0,000 0,01877911 0,07517893 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,01877911 0,07505405 ! opsonization GO:0008228 8 6 0,000 0,01877911 0,07492959 ! mating behavior GO:0007617 7 6 0,000 0,01877911 0,07480553 ! neuron remodeling GO:0016322 15 6 0,000 0,01877911 0,07468188 ! erythrocyte maturation GO:0043249 7 6 0,000 0,01877911 0,07455865 ! equilibrioception GO:0050957 14 6 0,000 0,01877911 0,07443582 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,01877911 0,07431339 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,01877911 0,07419136 ! photoreceptor cell development GO:0042461 10 6 0,000 0,01877911 0,07406974 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,01877911 0,07394851 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,01877911 0,07382768 ! response to interferon-gamma GO:0034341 15 6 0,000 0,01877911 0,07370724 ! toxin metabolic process GO:0009404 11 6 0,000 0,01877911 0,0735872 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,01877911 0,07346754 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,01877911 0,07334828 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,01877911 0,0732294 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,01877911 0,07311091 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,01877911 0,07299279 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,01877911 0,07287506 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,01877911 0,07275771 ! thymic T cell selection GO:0045061 12 6 0,000 0,01877911 0,07264074 ! protein lipoylation GO:0009249 10 6 0,000 0,01877911 0,07252414 ! cysteine metabolic process GO:0006534 10 6 0,000 0,01877911 0,07240792 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,01877911 0,07229206 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,01877911 0,07217658 ! glutamate catabolic process GO:0006538 10 6 0,000 0,01877911 0,07206147 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,01877911 0,07194672 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,01877911 0,07183234 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,01877911 0,07171832 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,01877911 0,07160466 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,01877911 0,07149136 ! hyperosmotic response GO:0006972 9 6 0,000 0,01877911 0,07137842 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,01877911 0,07126584 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,01877911 0,07115361 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,01877911 0,07104173 ! urea metabolic process GO:0019627 7 6 0,000 0,01877911 0,0709302 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,01877911 0,07081903 ! neutrophil activation GO:0042119 8 6 0,000 0,01877911 0,0707082 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,01877911 0,07059772 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,01877911 0,07048758 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,01877911 0,07037779 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,01877911 0,07026834 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,01877911 0,07015922 ! neuron apoptosis GO:0051402 9 6 0,000 0,01877911 0,07005045 ! nucleoside salvage GO:0043174 9 6 0,000 0,01877911 0,06994201 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,01877911 0,06983391 ! T cell mediated immunity GO:0002456 16 6 0,000 0,01877911 0,06972614 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,01877911 0,06961871 GO:0010543|regulation of platelet activation, ! carnitine transport GO:0015879 10 6 0,000 0,01877911 0,0695116 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,01877911 0,06940482 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01877911 0,06929837 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,01877911 0,06919225 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,01877911 0,06908645 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,01877911 0,06898098 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,01877911 0,06887582 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,01877911 0,06877099 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,01877911 0,06866647 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,01877911 0,06856228 ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,01877911 0,06845839 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,01877911 0,06835483 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,01877911 0,06825157 ! neural nucleus development GO:0048857 14 6 0,000 0,01877911 0,06814863 ! response to UV-C GO:0010225 11 6 0,000 0,01877911 0,06804599 ! astrocyte development GO:0014002 15 6 0,000 0,01877911 0,06794367 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,01877911 0,06784165 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,01877911 0,06773994 ! interaction with symbiont GO:0051702 13 6 0,000 0,01877911 0,06763853 ! regulation of dendrite development GO:0050773 16 6 0,000 0,01877911 0,06753743 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,01877911 0,06743663 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,01877911 0,06733612 ! response to copper ion GO:0046688 10 6 0,000 0,01877911 0,06723592 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,01877911 0,06713602 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,01877911 0,06703641 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01877911 0,0669371 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,01877911 0,06683808 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,01877911 0,06673935 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,01877911 0,06664091 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,01877911 0,06654277 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,01877911 0,06644491 ! hair follicle maturation GO:0048820 7 6 0,000 0,01877911 0,06634734 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,01877911 0,06625006 ! Schwann cell development GO:0014044 15 6 0,000 0,01877911 0,06615306 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,01877911 0,06605634 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,01877911 0,06595991 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,01877911 0,06586376 ! subpallium development GO:0021544 10 6 0,000 0,01877911 0,06576789 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,01877911 0,0656723 ! histone ubiquitination GO:0016574 8 6 0,000 0,01877911 0,06557698 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,01877911 0,06548194 ! maintenance of organ identity GO:0048496 9 6 0,000 0,01877911 0,06538718 ! G2 phase GO:0051319 16 6 0,000 0,01877911 0,06529269 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,01877911 0,06519847 ! establishment of planar polarity GO:0001736 7 6 0,000 0,01877911 0,06510452 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,01877911 0,06501085 ! membrane to membrane docking GO:0022614 14 6 0,000 0,01877911 0,06491744 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,01877911 0,0648243 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,01877911 0,06473143 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,01877911 0,06463883 ! receptor internalization GO:0031623 10 6 0,000 0,01877911 0,06454649 ! neutrophil homeostasis GO:0001780 10 6 0,000 0,01877911 0,06445441 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01877911 0,06436259 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,01877911 0,06427104 ! protein deubiquitination GO:0016579 14 6 0,000 0,01877911 0,06417974 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 0,01877911 0,06408871 ! protein destabilization GO:0031648 9 6 0,000 0,01877911 0,06399793 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,01877911 0,06390741 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,01877911 0,06381715 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,01877911 0,06372714 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,01877911 0,06363738 ! progesterone metabolic process GO:0042448 10 6 0,000 0,01877911 0,06354788 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,01877911 0,06345862 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,01877911 0,06336962 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,01877911 0,06328087 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,01877911 0,06319236 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,01877911 0,06310411 ! determination of adult lifespan GO:0008340 15 6 0,000 0,01877911 0,06301609 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,01877911 0,06292833 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,01877911 0,06284081 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,01877911 0,06275353 ! catecholamine transport GO:0051937 9 6 0,000 0,01877911 0,06266649 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,01877911 0,0625797 ! sensory cilium assembly GO:0035058 10 6 0,000 0,01877911 0,06249314 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,01877911 0,06240682 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,01877911 0,06232074 ! maternal placenta development GO:0001893 12 6 0,000 0,01877911 0,0622349 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,01877911 0,0621493 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,01877911 0,06206393 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,01877911 0,06197879 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,01877911 0,06189389 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,01877911 0,06180922 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,01877911 0,06172478 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,01877911 0,06164057 ! negative regulation of cell growth GO:0030308 132 67 1,000 0,0190587 0,06247308 ! chromosome segregation GO:0007059 113 67 1,000 0,0190587 0,06238808 ! adaptive immune response GO:0002250 119 67 1,000 0,0190587 0,06230331 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! regulation of lipase activity GO:0060191 130 68 1,000 0,01959644 0,06397425 ! cell cycle checkpoint GO:0000075 137 69 1,000 0,02014051 0,06566132 ! negative regulation of cell size GO:0045792 134 69 1,000 0,02014051 0,06557247 ! coenzyme biosynthetic process GO:0009108 102 69 1,000 0,02014051 0,06548386 ! appendage morphogenesis GO:0035107 135 70 1,000 0,02069087 0,0671825 GO:0035108|limb morphogenesis, ! appendage development GO:0048736 136 71 1,000 0,02124748 0,06889681 GO:0060173|limb development, ! phosphoinositide metabolic process GO:0030384 128 72 1,000 0,02181029 0,0706266 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 1,000 0,02181029 0,07053168 ! carbohydrate transport GO:0008643 110 72 1,000 0,02181029 0,070437 ! tRNA transcription GO:0009304 14 7 0,000 0,02187486 0,07055081 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,02187486 0,07045636 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,02187486 0,07036217 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,02187486 0,07026823 ! regulation of helicase activity GO:0051095 15 7 0,000 0,02187486 0,07017454 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,02187486 0,0700811 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,02187486 0,0699879 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,02187486 0,06989496 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,02187486 0,06980226 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,02187486 0,06970981 ! prostate gland development GO:0030850 13 7 0,000 0,02187486 0,0696176 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,02187486 0,06952563 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,02187486 0,06943391 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,02187486 0,06934243 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,02187486 0,06925119 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,02187486 0,06916019 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,02187486 0,06906943 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,02187486 0,0689789 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,02187486 0,06888862 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,02187486 0,06879857 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,02187486 0,06870875 ! glycolipid transport GO:0046836 10 7 0,000 0,02187486 0,06861917 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,02187486 0,06852982 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,02187486 0,06844071 ! neuron adhesion GO:0007158 12 7 0,000 0,02187486 0,06835182 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,02187486 0,06826317 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,02187486 0,06817474 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,02187486 0,06808655 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,02187486 0,06799858 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,02187486 0,06791084 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,02187486 0,06782333 ! pericardium development GO:0060039 14 7 0,000 0,02187486 0,06773604 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,02187486 0,06764898 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,02187486 0,06756213 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,02187486 0,06747552 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,02187486 0,06738912 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,02187486 0,06730294 ! lipoprotein transport GO:0042953 14 7 0,000 0,02187486 0,06721699 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,02187486 0,06713125 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,02187486 0,06704574 ! rhythmic behavior GO:0007622 15 7 0,000 0,02187486 0,06696044 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,02187486 0,06687535 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,02187486 0,06679049 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,02187486 0,06670583 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,02187486 0,0666214 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,02187486 0,06653717 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,02187486 0,06645316 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,02187486 0,06636936 ! mechanosensory behavior GO:0007638 14 7 0,000 0,02187486 0,06628577 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,02187486 0,06620239 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,02187486 0,06611922 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,02187486 0,06603626 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,02187486 0,06595351 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,02187486 0,06587097 ! spinal cord patterning GO:0021511 13 7 0,000 0,02187486 0,06578863 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,02187486 0,0657065 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,02187486 0,06562457 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,02187486 0,06554284 ! adrenal gland development GO:0030325 17 7 0,000 0,02187486 0,06546132 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,02187486 0,06538 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,02187486 0,06529889 ! ovulation GO:0030728 9 7 0,000 0,02187486 0,06521797 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,02187486 0,06513726 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,02187486 0,06505674 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,02187486 0,06497642 ! microtubule nucleation GO:0007020 20 7 0,000 0,02187486 0,0648963 ! proline biosynthetic process GO:0006561 10 7 0,000 0,02187486 0,06481638 ! thyroid hormone generation GO:0006590 13 7 0,000 0,02187486 0,06473666 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,02187486 0,06465713 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,02187486 0,06457779 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,02187486 0,06449866 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,02187486 0,06441971 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,02187486 0,06434096 ! galactose metabolic process GO:0006012 13 7 0,000 0,02187486 0,0642624 ! vesicle fusion GO:0006906 17 7 0,000 0,02187486 0,06418403 ! response to dietary excess GO:0002021 8 7 0,000 0,02187486 0,06410585 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,02187486 0,06402786 ! intracellular pH reduction GO:0051452 11 7 0,000 0,02187486 0,06395006 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,02187486 0,06387245 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,02187486 0,06379503 ! organ growth GO:0035265 15 7 0,000 0,02187486 0,0637178 ! purine salvage GO:0043101 10 7 0,000 0,02187486 0,06364075 ! nucleoside transport GO:0015858 8 7 0,000 0,02187486 0,06356389 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,02187486 0,06348722 ! parturition GO:0007567 14 7 0,000 0,02187486 0,06341073 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,02187486 0,06333442 ! rRNA modification GO:0000154 14 7 0,000 0,02187486 0,0632583 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,02187486 0,06318236 ! spindle checkpoint GO:0031577 15 7 0,000 0,02187486 0,0631066 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,02187486 0,06303102 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,02187486 0,06295563 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,02187486 0,06288041 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,02187486 0,06280537 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,02187486 0,06273052 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,02187486 0,06265584 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 0,02187486 0,06258134 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,02187486 0,06250701 ! fibrinolysis GO:0042730 10 7 0,000 0,02187486 0,06243286 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,02187486 0,06235889 ! eating behavior GO:0042755 7 7 0,000 0,02187486 0,06228509 ! B cell lineage commitment GO:0002326 21 7 0,000 0,02187486 0,06221147 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,02187486 0,06213802 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,02187486 0,06206474 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,02187486 0,06199164 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,02187486 0,06191871 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,02187486 0,06184595 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,02187486 0,06177336 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,02187486 0,06170094 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,02187486 0,06162869 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,02187486 0,06155661 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,02187486 0,0614847 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,02187486 0,06141296 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,02187486 0,06134138 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,02187486 0,06126997 ! regulation of meiosis GO:0040020 12 7 0,000 0,02187486 0,06119872 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,02187486 0,06112765 ! T cell lineage commitment GO:0002360 16 7 0,000 0,02187486 0,06105673 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,02187486 0,06098598 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,02187486 0,0609154 ! transcription termination GO:0006353 13 7 0,000 0,02187486 0,06084497 ! response to tumor cell GO:0002347 13 7 0,000 0,02187486 0,06077471 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,02187486 0,06070462 ! anaphase GO:0051322 17 7 0,000 0,02187486 0,06063468 GO:0000090|mitotic anaphase, ! axonal fasciculation GO:0007413 18 7 0,000 0,02187486 0,06056491 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,02187486 0,06049529 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,02187486 0,06042584 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,02187486 0,06035654 ! diuresis GO:0030146 12 7 0,000 0,02187486 0,0602874 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,02187486 0,06021842 ! thiamin metabolic process GO:0006772 7 7 0,000 0,02187486 0,0601496 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,02187486 0,06008094 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,02187486 0,06001243 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,02187486 0,05994408 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,02187486 0,05987588 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,02187486 0,05980784 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,02187486 0,05973996 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,02187486 0,05967223 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,02187486 0,05960465 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,02187486 0,05953722 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,02187486 0,05946995 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,02187486 0,05940282 ! lymph node development GO:0048535 10 7 0,000 0,02187486 0,05933585 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,02187486 0,05926903 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,02187486 0,05920237 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,02187486 0,05913585 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,02187486 0,05906948 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,02187486 0,05900325 ! adult feeding behavior GO:0008343 9 7 0,000 0,02187486 0,05893718 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,02187486 0,05887126 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,02187486 0,05880548 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,02187486 0,05873985 ! muscle adaptation GO:0043500 14 7 0,000 0,02187486 0,05867436 ! embryonic heart tube development GO:0035050 10 7 0,000 0,02187486 0,05860902 ! retina homeostasis GO:0001895 12 7 0,000 0,02187486 0,05854383 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,02187486 0,05847878 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,02187486 0,05841388 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,02187486 0,05834912 ! protein prenylation GO:0018342 18 7 0,000 0,02187486 0,0582845 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,02187486 0,05822003 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,02187486 0,05815569 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,02187486 0,0580915 ! regulation of transcription factor activity GO:0051090 126 74 1,000 0,02295436 0,06089106 GO:0090046|regulation of transcription regulator activity, ! meiosis GO:0007126 121 74 1,000 0,02295436 0,060824 GO:0051327|M phase of meiotic cell cycle, ! regulation of actin cytoskeleton organization GO:0032956 149 74 1,000 0,02295436 0,06075709 ! meiotic cell cycle GO:0051321 122 75 1,000 0,02353553 0,0622269 ! regulation of actin filament-based process GO:0032970 152 77 1,000 0,0247159 0,06527603 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 0,0247159 0,06520446 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,02496094 0,06577877 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,02496094 0,0657068 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,02496094 0,06563499 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,02496094 0,06556333 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,02496094 0,06549184 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,02496094 0,06542049 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,02496094 0,06534931 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,02496094 0,06527827 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,02496094 0,0652074 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,02496094 0,06513667 ! meiotic prophase I GO:0007128 13 8 0,000 0,02496094 0,0650661 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,02496094 0,06499568 ! oligopeptide transport GO:0006857 15 8 0,000 0,02496094 0,06492542 ! UTP metabolic process GO:0046051 8 8 0,000 0,02496094 0,06485531 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,02496094 0,06478534 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,02496094 0,06471553 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,02496094 0,06464587 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,02496094 0,06457636 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,02496094 0,064507 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,02496094 0,06443778 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,02496094 0,06436872 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,02496094 0,0642998 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,02496094 0,06423103 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,02496094 0,06416241 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,02496094 0,06409393 ! reflex GO:0060004 16 8 0,000 0,02496094 0,0640256 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,02496094 0,06395742 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,02496094 0,06388938 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,02496094 0,06382148 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,02496094 0,06375373 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,02496094 0,06368612 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,02496094 0,06361866 ! pigment granule organization GO:0048753 16 8 0,000 0,02496094 0,06355134 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,02496094 0,06348416 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,02496094 0,06341712 ! astrocyte differentiation GO:0048708 18 8 0,000 0,02496094 0,06335022 ! histidine metabolic process GO:0006547 16 8 0,000 0,02496094 0,06328347 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,02496094 0,06321686 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,02496094 0,06315038 ! glycine catabolic process GO:0006546 13 8 0,000 0,02496094 0,06308405 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,02496094 0,06301785 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,02496094 0,0629518 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 12 8 0,000 0,02496094 0,06288588 ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,02496094 0,0628201 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,02496094 0,06275445 ! melanin metabolic process GO:0006582 15 8 0,000 0,02496094 0,06268895 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,02496094 0,06262358 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,02496094 0,06255835 ! macrophage activation GO:0042116 12 8 0,000 0,02496094 0,06249325 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,02496094 0,06242829 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,02496094 0,06236346 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,02496094 0,06229877 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,02496094 0,06223421 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,02496094 0,06216979 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,02496094 0,06210549 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,02496094 0,06204134 ! osteoblast development GO:0002076 16 8 0,000 0,02496094 0,06197731 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,02496094 0,06191342 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,02496094 0,06184965 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,02496094 0,06178602 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,02496094 0,06172252 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,02496094 0,06165915 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,02496094 0,06159591 ! response to UV-B GO:0010224 16 8 0,000 0,02496094 0,0615328 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,02496094 0,06146982 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,02496094 0,06140697 ! intermediate filament organization GO:0045109 12 8 0,000 0,02496094 0,06134424 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,02496094 0,06128165 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,02496094 0,06121918 ! cellular extravasation GO:0045123 12 8 0,000 0,02496094 0,06115684 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,02496094 0,06109462 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,02496094 0,06103253 ! response to antibiotic GO:0046677 11 8 0,000 0,02496094 0,06097057 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,02496094 0,06090874 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,02496094 0,06084702 ! DNA topological change GO:0006265 12 8 0,000 0,02496094 0,06078544 ! response to tropane GO:0014073 15 8 0,000 0,02496094 0,06072398 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,02496094 0,06066264 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 0,000 0,02496094 0,06060143 ! melanosome transport GO:0032402 13 8 0,000 0,02496094 0,06054034 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,02496094 0,06047937 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,02496094 0,06041852 ! mast cell activation GO:0045576 14 8 0,000 0,02496094 0,0603578 ! multicellular organismal aging GO:0010259 18 8 0,000 0,02496094 0,0602972 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,02496094 0,06023672 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,02496094 0,06017637 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,02496094 0,06011613 ! nucleosome disassembly GO:0006337 14 8 0,000 0,02496094 0,06005601 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,02496094 0,05999602 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,02496094 0,05993614 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,02496094 0,05987638 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,02496094 0,05981675 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,02496094 0,05975723 ! intracellular lipid transport GO:0032365 13 8 0,000 0,02496094 0,05969783 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,02496094 0,05963854 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,02496094 0,05957938 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,02496094 0,05952033 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,02496094 0,0594614 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,02496094 0,05940258 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,02496094 0,05934389 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,02496094 0,0592853 ! hormone catabolic process GO:0042447 17 8 0,000 0,02496094 0,05922684 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,02496094 0,05916849 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,02496094 0,05911025 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,02496094 0,05905213 ! ATP catabolic process GO:0006200 11 8 0,000 0,02496094 0,05899412 ! blastocyst growth GO:0001832 19 8 0,000 0,02496094 0,05893622 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,02496094 0,05887844 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,02496094 0,05882078 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,02496094 0,05876322 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,02496094 0,05870578 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,02496094 0,05864845 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,02496094 0,05859123 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,02496094 0,05853413 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,02496094 0,05847713 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,02496094 0,05842025 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,02496094 0,05836347 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,02496094 0,05830681 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,02496094 0,05825025 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,02496094 0,05819381 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,02496094 0,05813748 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,02496094 0,05808125 GO:0000076|DNA replication checkpoint, ! NAD biosynthetic process GO:0009435 13 8 0,000 0,02496094 0,05802513 ! negative regulation of organelle organization GO:0010639 161 78 1,000 0,02531503 0,05879147 ! protein oligomerization GO:0051259 139 78 1,000 0,02531503 0,05873478 ! activation of protein kinase activity GO:0032147 147 79 1,000 0,02592006 0,0600806 ! axon extension GO:0048675 15 9 0,000 0,02803738 0,06492583 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,02803738 0,06486341 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,02803738 0,0648011 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,02803738 0,06473891 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,02803738 0,06467684 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,02803738 0,06461489 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,02803738 0,06455305 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,02803738 0,06449134 ! phosphate transport GO:0006817 19 9 0,000 0,02803738 0,06442974 ! reproductive behavior GO:0019098 19 9 0,000 0,02803738 0,06436827 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,02803738 0,0643069 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,02803738 0,06424566 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,02803738 0,06418453 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,02803738 0,06412352 ! GTP metabolic process GO:0046039 9 9 0,000 0,02803738 0,06406262 ! RNA methylation GO:0001510 15 9 0,000 0,02803738 0,06400184 ! elastic fiber assembly GO:0048251 15 9 0,000 0,02803738 0,06394118 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,02803738 0,06388063 ! artery development GO:0060840 24 9 0,000 0,02803738 0,06382019 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,02803738 0,06375987 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,02803738 0,06369966 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,02803738 0,06363957 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,02803738 0,06357959 ! chemosensory behavior GO:0007635 20 9 0,000 0,02803738 0,06351972 ! microtubule bundle formation GO:0001578 21 9 0,000 0,02803738 0,06345996 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,02803738 0,06340032 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,02803738 0,06334079 ! leukocyte degranulation GO:0043299 16 9 0,000 0,02803738 0,06328137 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,02803738 0,06322206 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,02803738 0,06316287 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,02803738 0,06310378 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,02803738 0,06304481 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,02803738 0,06298594 ! protein targeting to ER GO:0045047 22 9 0,000 0,02803738 0,06292718 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,02803738 0,06286854 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,02803738 0,06281 ! T cell selection GO:0045058 23 9 0,000 0,02803738 0,06275157 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,02803738 0,06269325 ! endosome organization GO:0007032 17 9 0,000 0,02803738 0,06263504 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,02803738 0,06257694 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,02803738 0,06251895 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,02803738 0,06246106 ! mannose metabolic process GO:0006013 13 9 0,000 0,02803738 0,06240328 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,02803738 0,0623456 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,02803738 0,06228803 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,02803738 0,06223057 ! receptor clustering GO:0043113 18 9 0,000 0,02803738 0,06217322 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,02803738 0,06211597 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,02803738 0,06205882 ! ruffle organization GO:0031529 15 9 0,000 0,02803738 0,06200178 ! retinol metabolic process GO:0042572 18 9 0,000 0,02803738 0,06194485 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,02803738 0,06188802 ! behavioral fear response GO:0001662 22 9 0,000 0,02803738 0,06183129 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,02803738 0,06177467 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,02803738 0,06171815 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,02803738 0,06166174 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 0,02803738 0,06160543 ! oligodendrocyte development GO:0014003 10 9 0,000 0,02803738 0,06154922 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,02803738 0,06149311 ! segment specification GO:0007379 13 9 0,000 0,02803738 0,06143711 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,02803738 0,0613812 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,02803738 0,0613254 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,02803738 0,0612697 ! response to amine stimulus GO:0014075 13 9 0,000 0,02803738 0,0612141 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,02803738 0,06115861 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,02803738 0,06110321 ! erythrocyte development GO:0048821 15 9 0,000 0,02803738 0,06104791 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,02803738 0,06099271 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,02803738 0,06093762 ! renal water homeostasis GO:0003091 14 9 0,000 0,02803738 0,06088262 ! postreplication repair GO:0006301 22 9 0,000 0,02803738 0,06082772 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,02803738 0,06077292 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,02803738 0,06071822 ! icosanoid secretion GO:0032309 15 9 0,000 0,02803738 0,06066362 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,02803738 0,06060911 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,02803738 0,06055471 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,02803738 0,0605004 ! regulation of cell division GO:0051302 15 9 0,000 0,02803738 0,06044618 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,02803738 0,06039207 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,02803738 0,06033805 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,02803738 0,06028413 ! sterol catabolic process GO:0016127 11 9 0,000 0,02803738 0,06023031 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,02803738 0,06017658 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,02803738 0,06012294 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,02803738 0,06006941 GO:0002820|negative regulation of adaptive immune response, ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,02803738 0,06001596 ! musculoskeletal movement GO:0050881 14 9 0,000 0,02803738 0,05996261 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,02803738 0,05990936 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,02803738 0,0598562 ! purine base metabolic process GO:0006144 21 9 0,000 0,02803738 0,05980314 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,02803738 0,05975017 ! pigment granule transport GO:0051904 17 9 0,000 0,02803738 0,05969729 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,02803738 0,05964451 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,02803738 0,05959182 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,02803738 0,05953922 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,02803738 0,05948672 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,02803738 0,05943431 ! mitochondrion localization GO:0051646 15 9 0,000 0,02803738 0,05938199 ! positive regulation of cell activation GO:0050867 145 85 1,000 0,02967182 0,06278838 GO:0002696|positive regulation of leukocyte activation, ! tube morphogenesis GO:0035239 176 86 1,000 0,03031698 0,06409724 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,03110422 0,06570392 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,03110422 0,06564628 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,03110422 0,06558875 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,03110422 0,06553131 ! synapsis GO:0007129 13 10 0,000 0,03110422 0,06547398 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,03110422 0,06541675 ! N-glycan processing GO:0006491 20 10 0,000 0,03110422 0,06535962 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,03110422 0,06530258 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,03110422 0,06524565 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,03110422 0,06518882 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,03110422 0,06513208 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,03110422 0,06507544 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 0,03110422 0,06501891 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,03110422 0,06496247 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,03110422 0,06490612 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,03110422 0,06484988 ! androgen metabolic process GO:0008209 17 10 0,000 0,03110422 0,06479373 ! phospholipid efflux GO:0033700 16 10 0,000 0,03110422 0,06473768 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,03110422 0,06468173 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,03110422 0,06462587 ! pathogenesis GO:0009405 13 10 0,000 0,03110422 0,06457011 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,03110422 0,06451445 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,03110422 0,06445888 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,03110422 0,06440341 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,03110422 0,06434803 ! endoderm development GO:0007492 16 10 0,000 0,03110422 0,06429275 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,03110422 0,06423756 ! arginine catabolic process GO:0006527 13 10 0,000 0,03110422 0,06418247 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,03110422 0,06412747 ! proline metabolic process GO:0006560 13 10 0,000 0,03110422 0,06407257 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,03110422 0,06401776 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,03110422 0,06396304 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,03110422 0,06390842 ! V(D)J recombination GO:0033151 28 10 0,000 0,03110422 0,06385389 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,03110422 0,06379946 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,03110422 0,06374511 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,03110422 0,06369086 ! B cell proliferation GO:0042100 18 10 0,000 0,03110422 0,0636367 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,03110422 0,06358263 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,03110422 0,06352866 ! multicellular organism growth GO:0035264 18 10 0,000 0,03110422 0,06347478 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,03110422 0,06342098 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,03110422 0,06336728 ! epithelial cell development GO:0002064 20 10 0,000 0,03110422 0,06331367 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,03110422 0,06326015 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,03110422 0,06320672 ! macroautophagy GO:0016236 17 10 0,000 0,03110422 0,06315339 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,03110422 0,06310014 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,03110422 0,06304698 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,03110422 0,06299391 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 0,03110422 0,06294093 ! copper ion homeostasis GO:0055070 13 10 0,000 0,03110422 0,06288803 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,03110422 0,06283523 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,03110422 0,06278252 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,03110422 0,06272989 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,03110422 0,06267735 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,03110422 0,0626249 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,03110422 0,06257254 ! blastoderm segmentation GO:0007350 18 10 0,000 0,03110422 0,06252027 ! response to dsRNA GO:0043331 20 10 0,000 0,03110422 0,06246808 ! DNA ligation GO:0006266 19 10 0,000 0,03110422 0,06241598 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,03110422 0,06236397 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,03110422 0,06231204 ! melanosome localization GO:0032400 16 10 0,000 0,03110422 0,0622602 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,03110422 0,06220845 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,03110422 0,06215678 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,03110422 0,0621052 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,03110422 0,0620537 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,03110422 0,06200229 ! mRNA cleavage GO:0006379 17 10 0,000 0,03110422 0,06195096 ! protein sumoylation GO:0016925 15 10 0,000 0,03110422 0,06189972 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,03110422 0,06184856 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,03110422 0,06179749 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,03110422 0,0617465 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,03110422 0,0616956 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,03110422 0,06164478 ! salivary gland development GO:0007431 27 10 0,000 0,03110422 0,06159404 ! prophase GO:0051324 15 10 0,000 0,03110422 0,06154339 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,03110422 0,06149282 ! apical protein localization GO:0045176 15 10 0,000 0,03110422 0,06144233 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,03110422 0,06139193 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,03110422 0,06134161 ! midbrain development GO:0030901 13 10 0,000 0,03110422 0,06129137 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,03110422 0,06124121 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,03110422 0,06119114 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,03110422 0,06114114 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,03110422 0,06109123 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,03110422 0,0610414 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,03110422 0,06099166 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,03110422 0,06094199 ! detection of calcium ion GO:0005513 23 10 0,000 0,03110422 0,0608924 ! oocyte development GO:0048599 17 10 0,000 0,03110422 0,0608429 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,03110422 0,06079347 ! blastocyst formation GO:0001825 17 10 0,000 0,03110422 0,06074412 ! cerebellar cortex development GO:0021695 15 10 0,000 0,03110422 0,06069486 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,03110422 0,06064567 ! activation of innate immune response GO:0002218 12 10 0,000 0,03110422 0,06059657 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,03110422 0,06054754 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,03110422 0,06049859 ! response to nicotine GO:0035094 20 10 0,000 0,03110422 0,06044973 ! establishment of cell polarity GO:0030010 16 10 0,000 0,03110422 0,06040094 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,03110422 0,06035223 ! cellular respiration GO:0045333 135 88 1,000 0,03162398 0,06131129 ! positive regulation of protein modification process GO:0031401 136 88 1,000 0,03162398 0,06126192 ! regulation of DNA binding GO:0051101 155 88 1,000 0,03162398 0,06121264 ! regulation of cell adhesion GO:0030155 212 89 1,000 0,03228574 0,06244331 ! regulation of cell cycle process GO:0010564 149 90 1,000 0,03295294 0,06368254 ! cofactor biosynthetic process GO:0051188 139 91 1,000 0,03362554 0,06493022 ! respiratory burst GO:0045730 17 11 0,000 0,03416149 0,06591222 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,03416149 0,06585941 ! neuron fate specification GO:0048665 17 11 0,000 0,03416149 0,06580668 ! telencephalon cell migration GO:0022029 20 11 0,000 0,03416149 0,06575403 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,03416149 0,06570147 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,03416149 0,065649 ! thyroid gland development GO:0030878 26 11 0,000 0,03416149 0,0655966 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,03416149 0,06554429 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,03416149 0,06549207 ! response to pain GO:0048265 24 11 0,000 0,03416149 0,06543992 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,03416149 0,06538786 ! T cell proliferation GO:0042098 26 11 0,000 0,03416149 0,06533588 ! bone resorption GO:0045453 16 11 0,000 0,03416149 0,06528399 ! ventral spinal cord development GO:0021517 21 11 0,000 0,03416149 0,06523218 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,03416149 0,06518045 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,03416149 0,0651288 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,03416149 0,06507723 ! melanocyte differentiation GO:0030318 21 11 0,000 0,03416149 0,06502575 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,03416149 0,06497434 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,03416149 0,06492302 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,03416149 0,06487178 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,03416149 0,06482062 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,03416149 0,06476954 ! lipid digestion GO:0044241 18 11 0,000 0,03416149 0,06471854 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,03416149 0,06466762 ! UV protection GO:0009650 19 11 0,000 0,03416149 0,06461678 ! adult heart development GO:0007512 14 11 0,000 0,03416149 0,06456602 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,03416149 0,06451534 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,03416149 0,06446474 ! temperature homeostasis GO:0001659 17 11 0,000 0,03416149 0,06441422 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,03416149 0,06436378 ! negative regulation of ossification GO:0030279 26 11 0,000 0,03416149 0,06431341 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,03416149 0,06426313 ! regulation of organ growth GO:0046620 13 11 0,000 0,03416149 0,06421292 ! pigment granule localization GO:0051875 20 11 0,000 0,03416149 0,0641628 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,03416149 0,06411275 ! vasoconstriction GO:0042310 18 11 0,000 0,03416149 0,06406278 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,03416149 0,06401288 ! embryonic axis specification GO:0000578 18 11 0,000 0,03416149 0,06396307 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,03416149 0,06391333 ! snRNA metabolic process GO:0016073 24 11 0,000 0,03416149 0,06386367 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,03416149 0,06381409 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,03416149 0,06376458 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,03416149 0,06371515 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,03416149 0,0636658 ! zymogen activation GO:0031638 15 11 0,000 0,03416149 0,06361652 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,03416149 0,06356732 ! neuroblast proliferation GO:0007405 24 11 0,000 0,03416149 0,06351819 ! nucleosome positioning GO:0016584 15 11 0,000 0,03416149 0,06346914 ! regulation of isotype switching GO:0045191 22 11 0,000 0,03416149 0,06342017 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,03416149 0,06337127 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,03416149 0,06332245 ! acid secretion GO:0046717 18 11 0,000 0,03416149 0,0632737 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,03416149 0,06322503 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,03416149 0,06317644 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,03416149 0,06312791 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,03416149 0,06307946 ! oocyte differentiation GO:0009994 18 11 0,000 0,03416149 0,06303109 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,03416149 0,06298279 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,03416149 0,06293457 ! cholesterol efflux GO:0033344 19 11 0,000 0,03416149 0,06288641 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,03416149 0,06283834 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,03416149 0,06279033 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,03416149 0,0627424 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,03416149 0,06269454 ! embryonic gut development GO:0048566 15 11 0,000 0,03416149 0,06264676 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,03416149 0,06259904 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,03416149 0,0625514 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,03416149 0,06250383 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,03416149 0,06245634 ! defense response to fungus GO:0050832 13 11 0,000 0,03416149 0,06240892 ! developmental induction GO:0031128 19 11 0,000 0,03416149 0,06236156 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,03416149 0,06231429 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,03416149 0,06226708 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,03416149 0,06221994 ! sequestering of metal ion GO:0051238 14 11 0,000 0,03416149 0,06217288 ! lamellipodium assembly GO:0030032 20 11 0,000 0,03416149 0,06212588 ! regulation of synapse organization GO:0050807 17 11 0,000 0,03416149 0,06207896 ! negative regulation of multicellular organismal process GO:0051241 166 93 1,000 0,03498681 0,06353077 ! forebrain development GO:0030900 188 95 1,000 0,03636924 0,06599124 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,03720921 0,06746447 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,03720921 0,06741367 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,03720921 0,06736295 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,03720921 0,0673123 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,03720921 0,06726173 ! mating GO:0007618 17 12 0,000 0,03720921 0,06721123 ! protein complex disassembly GO:0043241 27 12 0,000 0,03720921 0,06716081 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,03720921 0,06711046 ! hippocampus development GO:0021766 26 12 0,000 0,03720921 0,06706019 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 0,03720921 0,06701 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,03720921 0,06695988 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,03720921 0,06690983 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,03720921 0,06685986 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,03720921 0,06680997 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,03720921 0,06676015 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,03720921 0,0667104 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,03720921 0,06666073 ! drug transport GO:0015893 16 12 0,000 0,03720921 0,06661113 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,03720921 0,0665616 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,03720921 0,06651215 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,03720921 0,06646277 ! polyamine metabolic process GO:0006595 17 12 0,000 0,03720921 0,06641347 ! mitotic spindle organization GO:0007052 21 12 0,000 0,03720921 0,06636424 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,03720921 0,06631508 ! forebrain cell migration GO:0021885 21 12 0,000 0,03720921 0,06626599 ! asymmetric protein localization GO:0008105 20 12 0,000 0,03720921 0,06621698 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,03720921 0,06616804 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,03720921 0,06611917 ! fear response GO:0042596 26 12 0,000 0,03720921 0,06607037 ! monoamine transport GO:0015844 18 12 0,000 0,03720921 0,06602165 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,03720921 0,065973 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,03720921 0,06592442 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,03720921 0,06587591 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,03720921 0,06582747 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,03720921 0,0657791 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,03720921 0,06573081 ! protein homotetramerization GO:0051289 21 12 0,000 0,03720921 0,06568258 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,03720921 0,06563443 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,03720921 0,06558634 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,03720921 0,06553833 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,03720921 0,06549039 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,03720921 0,06544251 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,03720921 0,06539471 ! cranial nerve development GO:0021545 20 12 0,000 0,03720921 0,06534698 ! fucose catabolic process GO:0019317 22 12 0,000 0,03720921 0,06529931 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,03720921 0,06525172 ! histone methylation GO:0016571 26 12 0,000 0,03720921 0,06520419 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,03720921 0,06515674 ! autonomic nervous system development GO:0048483 24 12 0,000 0,03720921 0,06510935 ! gland morphogenesis GO:0022612 29 12 0,000 0,03720921 0,06506203 ! T cell homeostasis GO:0043029 25 12 0,000 0,03720921 0,06501478 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,03720921 0,0649676 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,03720921 0,06492049 ! spleen development GO:0048536 22 12 0,000 0,03720921 0,06487345 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,03720921 0,06482647 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,03720921 0,06477956 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,03720921 0,06473272 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,03720921 0,06468595 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,03720921 0,06463925 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 0,03720921 0,06459261 GO:0042130|negative regulation of T cell proliferation, ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,03720921 0,06454604 ! response to cold GO:0009409 17 12 0,000 0,03720921 0,06449954 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,03720921 0,0644531 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,03720921 0,06440673 ! regulation of DNA metabolic process GO:0051052 178 97 1,000 0,0377725 0,06533475 ! skeletal muscle tissue development GO:0007519 186 99 1,000 0,03919628 0,06774875 GO:0060538|skeletal muscle organ development, ! cell cycle arrest GO:0007050 213 100 1,000 0,03991578 0,06894283 ! cGMP metabolic process GO:0046068 18 13 0,000 0,04024741 0,06946576 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,04024741 0,06941597 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,04024741 0,06936624 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,04024741 0,06931659 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,04024741 0,06926701 ! lipid localization GO:0010876 28 13 0,000 0,04024741 0,06921749 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,04024741 0,06916805 ! organelle fusion GO:0048284 32 13 0,000 0,04024741 0,06911868 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,04024741 0,06906938 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,04024741 0,06902015 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,04024741 0,06897099 ! endocrine pancreas development GO:0031018 22 13 0,000 0,04024741 0,0689219 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,04024741 0,06887288 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,04024741 0,06882393 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,04024741 0,06877505 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,04024741 0,06872624 ! methionine metabolic process GO:0006555 27 13 0,000 0,04024741 0,0686775 ! plasma membrane organization GO:0007009 24 13 0,000 0,04024741 0,06862883 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,04024741 0,06858022 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,04024741 0,06853169 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,04024741 0,06848322 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,04024741 0,06843482 ! response to X-ray GO:0010165 25 13 0,000 0,04024741 0,06838649 ! cytokine metabolic process GO:0042107 22 13 0,000 0,04024741 0,06833823 ! exocrine system development GO:0035272 32 13 0,000 0,04024741 0,06829004 ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,04024741 0,06824191 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,04024741 0,06819386 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,04024741 0,06814587 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,04024741 0,06809794 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,04024741 0,06805009 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,04024741 0,0680023 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,04024741 0,06795458 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,04024741 0,06790693 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,04024741 0,06785934 ! regulation of cellular pH GO:0030641 22 13 0,000 0,04024741 0,06781182 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,04024741 0,06776436 ! ribosome assembly GO:0042255 17 13 0,000 0,04024741 0,06771698 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,04024741 0,06766965 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,04024741 0,0676224 ! chromatin silencing GO:0006342 26 13 0,000 0,04024741 0,06757521 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,04024741 0,06752809 ! regulation of epidermis development GO:0045682 19 13 0,000 0,04024741 0,06748103 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,04024741 0,06743404 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,04024741 0,06738711 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,04024741 0,06734025 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,04024741 0,06729345 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,04024741 0,06724672 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,04024741 0,06720005 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,04024741 0,06715345 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,04024741 0,06710691 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,04024741 0,06706044 ! insulin secretion GO:0030073 23 13 0,000 0,04024741 0,06701403 ! actin filament polymerization GO:0030041 24 13 0,000 0,04024741 0,06696769 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,04024741 0,06692141 ! acrosome reaction GO:0007340 18 13 0,000 0,04024741 0,06687519 ! rRNA transcription GO:0009303 25 14 0,000 0,04327613 0,07185809 ! lactation GO:0007595 26 14 0,000 0,04327613 0,07180853 ! reproductive cellular process GO:0048610 20 14 0,000 0,04327613 0,07175904 ! tRNA modification GO:0006400 20 14 0,000 0,04327613 0,07170962 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,04327613 0,07166027 ! regulation of S phase GO:0033261 23 14 0,000 0,04327613 0,07161098 ! water transport GO:0006833 21 14 0,000 0,04327613 0,07156177 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,04327613 0,07151262 ! non-recombinational repair GO:0000726 25 14 0,000 0,04327613 0,07146353 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,04327613 0,07141452 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,04327613 0,07136557 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,04327613 0,07131669 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,04327613 0,07126788 ! RNA polyadenylation GO:0043631 30 14 0,000 0,04327613 0,07121913 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,04327613 0,07117045 ! palate development GO:0060021 31 14 0,000 0,04327613 0,07112184 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,04327613 0,07107329 ! regulated secretory pathway GO:0045055 23 14 0,000 0,04327613 0,07102481 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,04327613 0,07097639 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,04327613 0,07092804 ! arginine metabolic process GO:0006525 17 14 0,000 0,04327613 0,07087976 ! regulation of heart rate GO:0002027 24 14 0,000 0,04327613 0,07083154 ! organic alcohol transport GO:0015850 29 14 0,000 0,04327613 0,07078339 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,04327613 0,0707353 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,04327613 0,07068728 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,04327613 0,07063933 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,04327613 0,07059144 ! neutral amino acid transport GO:0015804 26 14 0,000 0,04327613 0,07054361 ! L-amino acid transport GO:0015807 30 14 0,000 0,04327613 0,07049585 ! bone mineralization GO:0030282 17 14 0,000 0,04327613 0,07044815 ! stem cell development GO:0048864 43 14 0,000 0,04327613 0,07040052 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,04327613 0,07035295 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,04327613 0,07030545 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,04327613 0,07025801 ! cerebellum development GO:0021549 21 14 0,000 0,04327613 0,07021063 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,04327613 0,07016332 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,04327613 0,07011607 ! response to gamma radiation GO:0010332 28 14 0,000 0,04327613 0,07006889 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,04327613 0,07002177 ! cofactor transport GO:0051181 26 14 0,000 0,04327613 0,06997471 ! NADP metabolic process GO:0006739 24 14 0,000 0,04327613 0,06992772 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,04327613 0,06988078 ! intestinal absorption GO:0050892 25 14 0,000 0,04327613 0,06983392 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,04327613 0,06978711 ! oxygen transport GO:0015671 21 14 0,000 0,04327613 0,06974037 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,04327613 0,06969369 ! male genitalia development GO:0030539 24 14 0,000 0,04327613 0,06964707 ! regulation of axon extension GO:0030516 37 14 0,000 0,04327613 0,06960051 ! release of cytochrome c from mitochondria GO:0001836 30 14 0,000 0,04327613 0,06955402 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,04327613 0,06950759 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,04629539 0,07430734 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,04629539 0,0742578 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,04629539 0,07420833 ! superoxide anion generation GO:0042554 20 15 0,000 0,04629539 0,07415893 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,04629539 0,07410959 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,04629539 0,07406031 ! copper ion transport GO:0006825 20 15 0,000 0,04629539 0,0740111 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,04629539 0,07396196 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,04629539 0,07391288 ! sulfate transport GO:0008272 23 15 0,000 0,04629539 0,07386386 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,04629539 0,07381491 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,04629539 0,07376603 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,04629539 0,07371721 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,04629539 0,07366846 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,04629539 0,07361977 ! response to hexose stimulus GO:0009746 22 15 0,000 0,04629539 0,07357114 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,04629539 0,07352258 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,04629539 0,07347408 ! pituitary gland development GO:0021983 29 15 0,000 0,04629539 0,07342565 ! vesicle coating GO:0006901 33 15 0,000 0,04629539 0,07337728 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,04629539 0,07332897 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,04629539 0,07328073 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,04629539 0,07323255 ! regulation of exocytosis GO:0017157 22 15 0,000 0,04629539 0,07318443 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,04629539 0,07313638 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,04629539 0,07308839 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,04629539 0,07304046 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,04629539 0,0729926 ! regulation of vasodilation GO:0042312 26 15 0,000 0,04629539 0,0729448 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,04629539 0,07289706 ! histone deacetylation GO:0016575 20 15 0,000 0,04629539 0,07284938 ! mRNA splice site selection GO:0006376 38 15 0,000 0,04629539 0,07280177 ! tissue regeneration GO:0042246 26 15 0,000 0,04629539 0,07275422 ! water homeostasis GO:0030104 27 15 0,000 0,04629539 0,07270673 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,04629539 0,0726593 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,04629539 0,07261193 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,04629539 0,07256463 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,04629539 0,07251739 ! dopamine metabolic process GO:0042417 35 15 0,000 0,04629539 0,07247021 ! heme biosynthetic process GO:0006783 29 15 0,000 0,04629539 0,07242309 ! cell killing GO:0001906 29 15 0,000 0,04629539 0,07237603 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,04629539 0,07232903 ! detection of bacterium GO:0016045 18 15 0,000 0,04629539 0,07228209 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,04629539 0,07223522 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,04629539 0,0721884 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,04629539 0,07214165 ! peptide hormone processing GO:0016486 23 15 0,000 0,04629539 0,07209496 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,04930522 0,07673245 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,04930522 0,07668284 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,04930522 0,07663331 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,04930522 0,07658383 ! bone remodeling GO:0046849 27 16 0,000 0,04930522 0,07653443 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,04930522 0,07648508 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,04930522 0,0764358 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,04930522 0,07638658 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,04930522 0,07633743 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,04930522 0,07628833 ! startle response GO:0001964 28 16 0,000 0,04930522 0,07623931 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,04930522 0,07619034 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,04930522 0,07614144 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,04930522 0,0760926 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,04930522 0,07604382 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,04930522 0,07599511 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,04930522 0,07594645 ! protein polyubiquitination GO:0000209 34 16 0,000 0,04930522 0,07589786 ! glutamate metabolic process GO:0006536 22 16 0,000 0,04930522 0,07584934 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,04930522 0,07580087 ! response to osmotic stress GO:0006970 25 16 0,000 0,04930522 0,07575247 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,04930522 0,07570412 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,04930522 0,07565584 ! fructose metabolic process GO:0006000 25 16 0,000 0,04930522 0,07560762 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,04930522 0,07555947 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,04930522 0,07551137 ! intermediate filament-based process GO:0045103 32 16 0,000 0,04930522 0,07546333 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,04930522 0,07541536 ! negative regulation of immune response GO:0050777 35 16 0,000 0,04930522 0,07536745 ! axon cargo transport GO:0008088 43 16 0,000 0,04930522 0,07531959 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,04930522 0,0752718 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,04930522 0,07522407 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 0,04930522 0,0751764 ! DNA replication initiation GO:0006270 27 16 0,000 0,04930522 0,07512879 ! neuron recognition GO:0008038 35 16 0,000 0,04930522 0,07508124 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,04930522 0,07503375 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,04930522 0,07498632 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,04930522 0,07493895 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,04930522 0,07489164 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,04930522 0,07484439 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,04930522 0,0747972 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,04930522 0,07475007 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,04930522 0,074703 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,04930522 0,07465599 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,04930522 0,07460903 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 0,04930522 0,07456214 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,04930522 0,0745153 ! defense response to virus GO:0051607 37 16 0,000 0,04930522 0,07446853 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,05230565 0,07895069 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,05230565 0,07890119 ! metencephalon development GO:0022037 30 17 0,000 0,05230565 0,07885175 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,05230565 0,07880238 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,05230565 0,07875307 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,05230565 0,07870381 ! signal complex assembly GO:0007172 41 17 0,000 0,05230565 0,07865462 ! endothelial cell migration GO:0043542 28 17 0,000 0,05230565 0,0786055 ! inositol metabolic process GO:0006020 28 17 0,000 0,05230565 0,07855643 ! gene silencing by RNA GO:0031047 36 17 0,000 0,05230565 0,07850742 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,05230565 0,07845848 ! glial cell development GO:0021782 27 17 0,000 0,05230565 0,07840959 ! limbic system development GO:0021761 36 17 0,000 0,05230565 0,07836077 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,05230565 0,07831201 ! adult walking behavior GO:0007628 33 17 0,000 0,05230565 0,07826331 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,05230565 0,07821467 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,05230565 0,07816609 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,05230565 0,07811757 ! myoblast differentiation GO:0045445 45 17 0,000 0,05230565 0,07806911 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,05230565 0,07802071 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,05230565 0,07797237 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,05230565 0,07792409 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,05230565 0,07787587 ! glycine metabolic process GO:0006544 28 17 0,000 0,05230565 0,07782771 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,05230565 0,0777796 ! NAD metabolic process GO:0019674 29 17 0,000 0,05230565 0,07773156 ! membrane budding GO:0006900 37 17 0,000 0,05230565 0,07768358 ! DNA integration GO:0015074 29 17 0,000 0,05230565 0,07763566 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,05230565 0,07758779 ! regulation of protein binding GO:0043393 33 17 0,000 0,05230565 0,07753999 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,05230565 0,07749224 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,05230565 0,07744455 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,05230565 0,07739692 ! genitalia development GO:0048806 30 17 0,000 0,05230565 0,07734935 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,05230565 0,07730184 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,05230565 0,07725439 GO:0002712|regulation of B cell mediated immunity, ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,05230565 0,07720699 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,05230565 0,07715966 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,05230565 0,07711238 ! steroid catabolic process GO:0006706 31 17 0,000 0,05230565 0,07706516 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,05230565 0,07701799 ! gas transport GO:0015669 25 17 0,000 0,05230565 0,07697089 ! organic cation transport GO:0015695 31 17 0,000 0,05230565 0,07692384 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,05230565 0,07687685 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,05230565 0,07682991 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,05230565 0,07678304 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,05230565 0,07673622 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,05529671 0,08107489 ! neuron maturation GO:0042551 42 18 0,000 0,05529671 0,08102551 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,05529671 0,0809762 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,05529671 0,08092694 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,05529671 0,08087775 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,05529671 0,08082861 ! memory GO:0007613 31 18 0,000 0,05529671 0,08077954 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,05529671 0,08073052 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,05529671 0,08068156 ! patterning of blood vessels GO:0001569 39 18 0,000 0,05529671 0,08063266 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,05529671 0,08058382 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,05529671 0,08053505 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,05529671 0,08048632 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,05529671 0,08043766 ! glutamine metabolic process GO:0006541 29 18 0,000 0,05529671 0,08038906 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,05529671 0,08034052 ! response to fungus GO:0009620 21 18 0,000 0,05529671 0,08029203 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,05529671 0,0802436 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,05529671 0,08019523 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,05529671 0,08014692 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,05529671 0,08009867 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,05529671 0,08005048 ! vitamin transport GO:0051180 27 18 0,000 0,05529671 0,08000234 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,05529671 0,07995426 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,05529671 0,07990624 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,05529671 0,07985828 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,05529671 0,07981037 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,05529671 0,07976253 ! nerve development GO:0021675 28 18 0,000 0,05529671 0,07971474 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,05529671 0,079667 ! protein secretion GO:0009306 39 19 0,000 0,05827844 0,08391258 ! positive regulation of translation GO:0045727 30 19 0,000 0,05827844 0,08386239 ! negative regulation of defense response GO:0031348 25 19 0,000 0,05827844 0,08381226 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,05827844 0,0837622 ! skin development GO:0043588 36 19 0,000 0,05827844 0,08371219 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,05827844 0,08366224 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,05827844 0,08361235 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,05827844 0,08356252 ! bile acid metabolic process GO:0008206 29 19 0,000 0,05827844 0,08351275 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,05827844 0,08346304 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,05827844 0,08341339 ! cerebral cortex development GO:0021987 36 19 0,000 0,05827844 0,0833638 ! pigmentation during development GO:0048066 41 19 0,000 0,05827844 0,08331427 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,05827844 0,08326479 GO:0030968|endoplasmic reticulum unfolded protein response, ! heme metabolic process GO:0042168 36 19 0,000 0,05827844 0,08321538 ! neuromuscular junction development GO:0007528 34 19 0,000 0,05827844 0,08316602 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,05827844 0,08311672 ! peptide cross-linking GO:0018149 37 19 0,000 0,05827844 0,08306749 ! protein export from nucleus GO:0006611 36 19 0,000 0,05827844 0,0830183 ! heart process GO:0003015 30 19 0,000 0,05827844 0,08296918 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,05827844 0,08292012 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,05827844 0,08287111 ! visual learning GO:0008542 36 19 0,000 0,05827844 0,08282216 ! cellular pigmentation GO:0033059 36 19 0,000 0,05827844 0,08277327 ! G1 phase GO:0051318 40 19 0,000 0,05827844 0,08272443 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,05827844 0,08267566 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,05827844 0,08262694 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,05827844 0,08257828 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,05827844 0,08252967 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,05827844 0,08248113 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,05827844 0,08243264 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,05827844 0,0823842 ! cilium assembly GO:0042384 37 19 0,000 0,05827844 0,08233583 ! peptide hormone secretion GO:0030072 31 19 0,000 0,05827844 0,08228751 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,06125084 0,08643374 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,06125084 0,08638308 ! positive regulation of ossification GO:0045778 47 20 0,000 0,06125084 0,08633247 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,06125084 0,08628193 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,06125084 0,08623144 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 0,000 0,06125084 0,08618101 ! cAMP metabolic process GO:0046058 36 20 0,000 0,06125084 0,08613064 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,06125084 0,08608033 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,06125084 0,08603008 ! response to alkaloid GO:0043279 38 20 0,000 0,06125084 0,08597989 ! retinoid metabolic process GO:0001523 32 20 0,000 0,06125084 0,08592975 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,06125084 0,08587968 ! apoptotic mitochondrial changes GO:0008637 41 20 0,000 0,06125084 0,08582966 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,06125084 0,0857797 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,06125084 0,0857298 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,06125084 0,08567996 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 0,000 0,06125084 0,08563017 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,06125084 0,08558045 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,06125084 0,08553078 ! body fluid secretion GO:0007589 31 20 0,000 0,06125084 0,08548117 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,06125084 0,08543161 ! peptide secretion GO:0002790 35 20 0,000 0,06125084 0,08538211 ! stem cell differentiation GO:0048863 53 20 0,000 0,06125084 0,08533267 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,06125084 0,08528329 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,06125084 0,08523397 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,06125084 0,0851847 ! sensory perception of pain GO:0019233 30 20 0,000 0,06125084 0,08513549 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,06125084 0,08508633 ! diencephalon development GO:0021536 34 20 0,000 0,06125084 0,08503724 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,06125084 0,08498819 GO:0006626|protein targeting to mitochondrion, ! detection of chemical stimulus GO:0009593 37 20 0,000 0,06125084 0,08493921 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,06125084 0,08489028 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,06125084 0,08484141 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,06125084 0,08479259 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,06125084 0,08474384 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,06125084 0,08469513 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,06125084 0,08464648 ! regulation of glucose import GO:0046324 29 20 0,000 0,06125084 0,08459789 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,06125084 0,08454936 ! actin filament-based movement GO:0030048 43 20 0,000 0,06125084 0,08450088 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,06125084 0,08445245 ! negative regulation of T cell activation GO:0050868 40 20 0,000 0,06125084 0,08440408 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,06125084 0,08435577 ! negative regulation of translation GO:0017148 29 20 0,000 0,06125084 0,08430751 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,06125084 0,08425931 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,06125084 0,08421116 ! regulation of cell killing GO:0031341 42 21 0,000 0,06421397 0,08823461 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,06421397 0,08818425 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,06421397 0,08813395 ! hormone secretion GO:0046879 38 21 0,000 0,06421397 0,0880837 ! glycerol metabolic process GO:0006071 34 21 0,000 0,06421397 0,08803351 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,06421397 0,08798338 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,06421397 0,0879333 ! axis specification GO:0009798 38 21 0,000 0,06421397 0,08788328 ! ovarian follicle development GO:0001541 35 21 0,000 0,06421397 0,08783332 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,06421397 0,08778341 ! smooth muscle contraction GO:0006939 46 21 0,000 0,06421397 0,08773356 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,06421397 0,08768377 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,06421397 0,08763404 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,06421397 0,08758436 ! cell aging GO:0007569 44 21 0,000 0,06421397 0,08753474 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,06421397 0,08748517 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,06421397 0,08743566 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,06421397 0,0873862 ! cytolysis GO:0019835 24 21 0,000 0,06421397 0,0873368 ! vasodilation GO:0042311 39 21 0,000 0,06421397 0,08728746 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,06421397 0,08723818 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,06421397 0,08718894 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,06421397 0,08713977 ! oogenesis GO:0048477 36 21 0,000 0,06421397 0,08709065 ! DNA modification GO:0006304 34 21 0,000 0,06421397 0,08704158 ! collagen fibril organization GO:0030199 59 21 0,000 0,06421397 0,08699257 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,06421397 0,08694362 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,06421397 0,08689472 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,06421397 0,08684587 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,06421397 0,08679708 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,06421397 0,08674835 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,06421397 0,08669967 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,06421397 0,08665104 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,06421397 0,08660247 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,06421397 0,08655395 ! collagen catabolic process GO:0030574 28 21 0,000 0,06421397 0,08650549 ! sperm-egg recognition GO:0035036 21 21 0,000 0,06421397 0,08645708 ! gut development GO:0048565 39 21 0,000 0,06421397 0,08640873 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,06716784 0,09033305 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,06716784 0,09028258 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,06716784 0,09023217 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,06716784 0,09018182 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,06716784 0,09013152 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,06716784 0,09008128 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,06716784 0,0900311 ! regeneration GO:0031099 41 22 0,000 0,06716784 0,08998097 ! keratinization GO:0031424 28 22 0,000 0,06716784 0,0899309 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,06716784 0,08988088 ! sensory perception of taste GO:0050909 28 22 0,000 0,06716784 0,08983092 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,06716784 0,08978101 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,06716784 0,08973116 ! vacuolar transport GO:0007034 36 22 0,000 0,06716784 0,08968136 ! lysosome organization GO:0007040 41 22 0,000 0,06716784 0,08963162 ! central nervous system neuron development GO:0021954 46 22 0,000 0,06716784 0,08958194 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,06716784 0,08953231 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,06716784 0,08948273 ! fucose metabolic process GO:0006004 39 22 0,000 0,06716784 0,08943321 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,06716784 0,08938375 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,06716784 0,08933434 ! ureteric bud development GO:0001657 43 22 0,000 0,06716784 0,08928498 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,06716784 0,08923568 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,06716784 0,08918643 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,06716784 0,08913724 ! positive regulation of intracellular transport GO:0032388 37 22 0,000 0,06716784 0,0890881 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,06716784 0,08903902 ! sarcomere organization GO:0045214 30 22 0,000 0,06716784 0,08898999 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,06716784 0,08894101 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,06716784 0,08889209 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,06716784 0,08884322 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,06716784 0,08879441 ! protein stabilization GO:0050821 39 22 0,000 0,06716784 0,08874564 ! positive regulation of cell adhesion GO:0045785 56 23 0,000 0,07011248 0,09258542 ! gluconeogenesis GO:0006094 33 23 0,000 0,07011248 0,09253463 ! viral genome replication GO:0019079 41 23 0,000 0,07011248 0,0924839 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,07011248 0,09243322 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,07011248 0,0923826 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,07011248 0,09233204 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,07011248 0,09228153 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,07011248 0,09223107 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,07011248 0,09218067 ! visual behavior GO:0007632 42 23 0,000 0,07011248 0,09213033 ! regulation of DNA recombination GO:0000018 48 23 0,000 0,07011248 0,09208004 ! response to ethanol GO:0045471 46 23 0,000 0,07011248 0,0920298 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,07011248 0,09197963 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,07011248 0,0919295 ! peroxisome organization GO:0007031 37 23 0,000 0,07011248 0,09187943 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,07011248 0,09182941 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,07011248 0,09177945 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,07011248 0,09172954 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,07011248 0,09167969 GO:0051693|actin filament capping, ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,07011248 0,09162989 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,07011248 0,09158015 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,07011248 0,09153046 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,07011248 0,09148082 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,07011248 0,09143124 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,07011248 0,09138171 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,07011248 0,09133223 ! fatty acid transport GO:0015908 44 23 0,000 0,07011248 0,09128281 ! platelet activation GO:0030168 37 23 0,000 0,07011248 0,09123344 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,07011248 0,09118413 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,07011248 0,09113486 ! hormone transport GO:0009914 40 23 0,000 0,07011248 0,09108565 ! cell-cell recognition GO:0009988 25 23 0,000 0,07011248 0,0910365 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,07011248 0,0909874 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,07011248 0,09093835 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,07011248 0,09088935 ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,07011248 0,09084041 ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,07304793 0,09459274 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,07304793 0,09454186 GO:0016444|somatic cell DNA recombination, ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,07304793 0,09449103 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,07304793 0,09444026 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,07304793 0,09438954 ! vesicle docking GO:0048278 47 24 0,000 0,07304793 0,09433887 ! spinal cord development GO:0021510 47 24 0,000 0,07304793 0,09428826 ! vacuole organization GO:0007033 43 24 0,000 0,07304793 0,0942377 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,07304793 0,0941872 ! digestive system process GO:0022600 39 24 0,000 0,07304793 0,09413675 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,07304793 0,09408636 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,07304793 0,09403602 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,07304793 0,09398573 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,07304793 0,0939355 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,07304793 0,09388532 ! membrane depolarization GO:0051899 39 24 0,000 0,07304793 0,09383519 ! pallium development GO:0021543 49 24 0,000 0,07304793 0,09378512 ! pentose metabolic process GO:0019321 35 24 0,000 0,07304793 0,0937351 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,07304793 0,09368514 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,07304793 0,09363522 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,07304793 0,09358537 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,07304793 0,09353556 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,07304793 0,09348581 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,07304793 0,09343611 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,07304793 0,09338646 ! regulation of amine transport GO:0051952 40 24 0,000 0,07304793 0,09333686 ! myelination GO:0042552 45 25 0,000 0,07597421 0,09702438 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,07597421 0,09697291 ! phototransduction GO:0007602 33 25 0,000 0,07597421 0,09692149 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,07597421 0,09687013 GO:0006479|protein amino acid methylation, ! sperm motility GO:0030317 31 25 0,000 0,07597421 0,09681882 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,07597421 0,09676757 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,07597421 0,09671637 ! receptor metabolic process GO:0043112 46 25 0,000 0,07597421 0,09666522 ! chromosome condensation GO:0030261 45 25 0,000 0,07597421 0,09661413 ! response to starvation GO:0042594 42 25 0,000 0,07597421 0,09656309 ! response to endoplasmic reticulum stress GO:0034976 43 25 0,000 0,07597421 0,09651211 ! negative regulation of cell development GO:0010721 73 25 0,000 0,07597421 0,09646118 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,07597421 0,0964103 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,07597421 0,09635948 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,07597421 0,09630871 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,07597421 0,096258 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! immunoglobulin production GO:0002377 55 25 0,000 0,07597421 0,09620734 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,07597421 0,09615673 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,07597421 0,09610617 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,07597421 0,09605567 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,07597421 0,09600522 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,07597421 0,09595482 ! telomere organization GO:0032200 43 25 0,000 0,07597421 0,09590448 GO:0000723|telomere maintenance, ! liver development GO:0001889 53 25 0,000 0,07597421 0,09585419 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,07889134 0,09948248 ! embryonic pattern specification GO:0009880 44 26 0,000 0,07889134 0,09943036 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,07889134 0,09937831 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,07889134 0,0993263 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,07889134 0,09927435 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,07889134 0,09922246 ! molting cycle process GO:0022404 50 26 0,000 0,07889134 0,09917062 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,07889134 0,09911883 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,07889134 0,0990671 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,07889134 0,09901542 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,07889134 0,0989638 GO:0051297|centrosome organization, ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,07889134 0,09891223 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,07889134 0,09886071 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,07889134 0,09880925 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,07889134 0,09875784 ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,07889134 0,09870648 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,07889134 0,09865518 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,07889134 0,09860393 ! blastocyst development GO:0001824 49 26 0,000 0,07889134 0,09855273 ! leukocyte proliferation GO:0070661 52 26 0,000 0,07889134 0,09850159 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,07889134 0,0984505 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,07889134 0,09839946 ! neuron fate commitment GO:0048663 48 27 0,000 0,08179936 0,10197371 ! iron ion transport GO:0006826 59 27 0,000 0,08179936 0,10192091 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,08179936 0,10186815 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,08179936 0,10181545 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,08179936 0,10176281 ! fat cell differentiation GO:0045444 50 27 0,000 0,08179936 0,10171022 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,08179936 0,10165768 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,08179936 0,1016052 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,08179936 0,10155277 ! autophagy GO:0006914 41 27 0,000 0,08179936 0,1015004 ! male gonad development GO:0008584 44 27 0,000 0,08179936 0,10144808 ! response to toxin GO:0009636 47 27 0,000 0,08179936 0,10139581 ! base-excision repair GO:0006284 41 27 0,000 0,08179936 0,1013436 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,08179936 0,10129144 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,08179936 0,10123934 ! glutathione metabolic process GO:0006749 39 27 0,000 0,08179936 0,10118729 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,08179936 0,10113529 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,08179936 0,10108334 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,08179936 0,10103145 ! negative regulation of lymphocyte activation GO:0051250 53 27 0,000 0,08179936 0,10097962 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,0846983 0,10450467 ! circadian rhythm GO:0007623 50 28 0,000 0,0846983 0,10445111 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,0846983 0,1043976 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,0846983 0,10434415 ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,0846983 0,10429075 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,0846983 0,1042374 ! ER-nuclear signaling pathway GO:0006984 48 28 0,000 0,0846983 0,10418411 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,0846983 0,10413087 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,0846983 0,10407769 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,0846983 0,10402456 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,0846983 0,10397149 ! synaptogenesis GO:0007416 42 28 0,000 0,0846983 0,10391847 ! lipid oxidation GO:0034440 43 28 0,000 0,0846983 0,1038655 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,0846983 0,10381259 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,0846983 0,10375973 ! translational initiation GO:0006413 65 29 0,000 0,08758818 0,10724538 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,08758818 0,10719083 ! regulation of pH GO:0006885 43 29 0,000 0,08758818 0,10713634 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,08758818 0,1070819 ! catechol metabolic process GO:0009712 54 29 0,000 0,08758818 0,10702751 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,08758818 0,10697318 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,08758818 0,10691891 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,08758818 0,10686469 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,08758818 0,10681053 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,08758818 0,10675642 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,08758818 0,10670237 ! cell fate determination GO:0001709 60 29 0,000 0,08758818 0,10664837 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,08758818 0,10659442 ! detection of light stimulus GO:0009583 38 29 0,000 0,08758818 0,10654053 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,08758818 0,1064867 ! tissue homeostasis GO:0001894 48 29 0,000 0,08758818 0,10643292 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,08758818 0,10637919 ! phenol metabolic process GO:0018958 55 30 0,000 0,09046904 0,10982266 ! zinc ion transport GO:0006829 45 30 0,000 0,09046904 0,10976727 ! membrane docking GO:0022406 61 30 0,000 0,09046904 0,10971195 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,09046904 0,10965668 ! regulation of innate immune response GO:0045088 51 30 0,000 0,09046904 0,10960146 ! acute-phase response GO:0006953 49 30 0,000 0,09046904 0,1095463 ! myofibril assembly GO:0030239 47 30 0,000 0,09046904 0,1094912 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,09046904 0,10943615 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,09046904 0,10938116 ! phospholipid transport GO:0015914 51 30 0,000 0,09046904 0,10932622 ! ensheathment of neurons GO:0007272 57 30 0,000 0,09046904 0,10927134 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,09046904 0,10921651 GO:0046496|nicotinamide nucleotide metabolic process, ! negative regulation of leukocyte activation GO:0002695 56 30 0,000 0,09046904 0,10916174 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,09046904 0,10910702 ! eye morphogenesis GO:0048592 60 30 0,000 0,09046904 0,10905236 ! response to heat GO:0009408 50 30 0,000 0,09046904 0,10899775 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,09334089 0,11240149 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,09334089 0,11234526 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,09334089 0,11228909 GO:0009799|determination of symmetry, ! inner ear morphogenesis GO:0042472 47 31 0,000 0,09334089 0,11223298 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,09334089 0,11217692 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,09334089 0,11212091 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,09334089 0,11206496 ! ovulation cycle process GO:0022602 49 31 0,000 0,09334089 0,11200907 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,09334089 0,11195323 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,09334089 0,11189745 ! peptide transport GO:0015833 55 31 0,000 0,09334089 0,11184173 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,09334089 0,11178605 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,09334089 0,11173044 ! mesoderm formation GO:0001707 69 31 0,000 0,09334089 0,11167488 ! natural killer cell activation GO:0030101 45 31 0,000 0,09334089 0,11161938 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,09334089 0,11156393 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,09334089 0,11150853 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,09334089 0,11145319 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,09334089 0,11139791 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,09334089 0,11134268 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,09620377 0,11470083 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,09620377 0,11464402 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,09620377 0,11458726 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,09620377 0,11453057 ! cholesterol transport GO:0030301 56 32 0,000 0,09620377 0,11447392 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,09620377 0,11441734 ! spliceosome assembly GO:0000245 67 32 0,000 0,09620377 0,11436081 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,09620377 0,11430433 ! metanephros development GO:0001656 74 32 0,000 0,09620377 0,11424791 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,09620377 0,11419155 ! response to ionizing radiation GO:0010212 65 32 0,000 0,09620377 0,11413524 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,09620377 0,11407899 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,09620377 0,1140228 ! regulation of protein import into nucleus GO:0042306 63 32 0,000 0,09620377 0,11396665 ! muscle cell development GO:0055001 49 32 0,000 0,09620377 0,11391057 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,09620377 0,11385454 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,09620377 0,11379856 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,09620377 0,11374264 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,09620377 0,11368678 ! ovulation cycle GO:0042698 51 32 0,000 0,09620377 0,11363096 ! peripheral nervous system development GO:0007422 64 32 0,000 0,09620377 0,11357521 ! BMP signaling pathway GO:0030509 64 32 0,000 0,09620377 0,11351951 ! hindbrain development GO:0030902 61 32 0,000 0,09620377 0,11346386 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,09620377 0,11340827 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,09620377 0,11335273 ! gene silencing GO:0016458 65 32 0,000 0,09620377 0,11329725 ! post-embryonic development GO:0009791 69 33 0,000 0,09905771 0,11660119 ! protein targeting to membrane GO:0006612 68 33 0,000 0,09905771 0,11654418 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,09905771 0,11648722 ! ceramide metabolic process GO:0006672 64 33 0,000 0,09905771 0,11643031 ! formation of primary germ layer GO:0001704 72 33 0,000 0,09905771 0,11637346 ! cell fate specification GO:0001708 52 33 0,000 0,09905771 0,11631666 ! sterol transport GO:0015918 57 33 0,000 0,09905771 0,11625992 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,09905771 0,11620324 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,09905771 0,11614661 ! adult locomotory behavior GO:0008344 59 33 0,000 0,09905771 0,11609004 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,09905771 0,11603352 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,09905771 0,11597705 ! glial cell differentiation GO:0010001 63 34 0,000 0,10190272 0,11924998 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,10190272 0,11919201 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,10190272 0,11913409 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,10190272 0,11907623 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,10190272 0,11901842 ! spermatid development GO:0007286 63 34 0,000 0,10190272 0,11896068 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,10190272 0,11890299 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,10190272 0,11884535 ! negative regulation of secretion GO:0051048 63 35 0,000 0,10473885 0,12209384 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,10473885 0,12203471 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,10473885 0,12197564 ! odontogenesis GO:0042476 66 35 0,000 0,10473885 0,12191663 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,10473885 0,12185768 ! female gonad development GO:0008585 58 35 0,000 0,10473885 0,12179878 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,10473885 0,12173994 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,10473885 0,12168116 ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 0,10473885 0,12162243 ! cytokine production GO:0001816 59 35 0,000 0,10473885 0,12156376 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,10473885 0,12150515 ! vesicle localization GO:0051648 64 35 0,000 0,10473885 0,12144659 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,10756612 0,12466478 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,10756612 0,12460476 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,10756612 0,12454479 ! positive regulation of cell development GO:0010720 80 36 0,000 0,10756612 0,12448489 ! regulation of proteolysis GO:0030162 72 36 0,000 0,10756612 0,12442504 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,10756612 0,12436525 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,10756612 0,12430551 ! androgen receptor signaling pathway GO:0030521 74 36 0,000 0,10756612 0,12424584 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,10756612 0,12418622 ! negative regulation of cell activation GO:0050866 65 36 0,000 0,10756612 0,12412666 ! RNA export from nucleus GO:0006405 56 37 0,000 0,11038455 0,12731794 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,11038455 0,12725694 ! actomyosin structure organization GO:0031032 62 37 0,000 0,11038455 0,12719599 ! organic anion transport GO:0015711 68 37 0,000 0,11038455 0,1271351 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,11038455 0,12707427 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,11038455 0,1270135 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,11038455 0,12695278 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,11038455 0,12689213 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,11038455 0,12683153 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,11038455 0,12677099 ! glycogen metabolic process GO:0005977 61 37 0,000 0,11038455 0,12671051 ! pigment metabolic process GO:0042440 80 37 0,000 0,11038455 0,12665008 ! spermatid differentiation GO:0048515 66 37 0,000 0,11038455 0,12658972 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,11319417 0,12974997 GO:0006956|complement activation, ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,11319417 0,12968818 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,11319417 0,12962645 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,11319417 0,12956479 ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,11319417 0,12950318 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 0,000 0,11319417 0,12944163 ! lipid homeostasis GO:0055088 67 38 0,000 0,11319417 0,12938013 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,11319417 0,1293187 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,11319417 0,12925732 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,11319417 0,12919601 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,11319417 0,12913475 ! glucan metabolic process GO:0044042 62 38 0,000 0,11319417 0,12907354 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,11599502 0,13220465 ! mammary gland development GO:0030879 86 39 0,000 0,11599502 0,13214205 ! learning GO:0007612 77 39 0,000 0,11599502 0,13207951 ! ear morphogenesis GO:0042471 60 39 0,000 0,11599502 0,13201703 ! organic ether metabolic process GO:0018904 55 39 0,000 0,11599502 0,13195461 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,11599502 0,13189225 ! ion transmembrane transport GO:0034220 66 39 0,000 0,11599502 0,13182995 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,11599502 0,13176771 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,11599502 0,13170552 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,11599502 0,1316434 ! RNA modification GO:0009451 57 39 0,000 0,11599502 0,13158133 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,11599502 0,13151932 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,11878711 0,13462166 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,11878711 0,13455827 ! feeding behavior GO:0007631 59 40 0,000 0,11878711 0,13449495 ! negative regulation of binding GO:0051100 72 40 0,000 0,11878711 0,13443169 ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,11878711 0,13436849 ! maintenance of protein location GO:0045185 91 40 0,000 0,11878711 0,13430535 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,12157047 0,13738776 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,12157047 0,13732326 ! gliogenesis GO:0042063 88 41 0,000 0,12157047 0,13725882 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,12157047 0,13719444 ! regulation of T cell proliferation GO:0042129 71 41 0,000 0,12157047 0,13713012 ! T cell differentiation GO:0030217 81 41 0,000 0,12157047 0,13706586 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,12157047 0,13700166 ! regulation of T cell differentiation GO:0045580 70 41 0,000 0,12157047 0,13693752 ! female gamete generation GO:0007292 61 41 0,000 0,12157047 0,13687344 ! polyol metabolic process GO:0019751 66 41 0,000 0,12157047 0,13680942 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,12157047 0,13674546 ! response to reactive oxygen species GO:0000302 67 42 0,000 0,12434513 0,13980112 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,12434513 0,13973582 ! regulation of tube size GO:0035150 71 42 0,000 0,12434513 0,13967058 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,12434513 0,13960541 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,12434513 0,13954029 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,12434513 0,13947524 ! regulation of intracellular protein transport GO:0033157 80 42 0,000 0,12434513 0,13941025 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,12434513 0,13934531 ! regulation of protein secretion GO:0050708 71 42 0,000 0,12434513 0,13928044 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,12711113 0,14231241 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,12711113 0,14224622 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,12711113 0,14218009 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,12711113 0,14211402 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,12711113 0,14204801 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,12711113 0,14198206 ! striated muscle contraction GO:0006941 77 43 0,000 0,12711113 0,14191618 ! phagocytosis GO:0006909 90 43 0,000 0,12711113 0,14185036 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,12711113 0,14178459 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,12986847 0,14479312 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,12986847 0,14472605 ! male sex differentiation GO:0046661 76 44 0,000 0,12986847 0,14465905 ! double-strand break repair GO:0006302 81 44 0,000 0,12986847 0,14459211 ! biopolymer methylation GO:0043414 84 44 0,000 0,12986847 0,14452523 ! B cell differentiation GO:0030183 107 44 0,000 0,12986847 0,14445841 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,12986847 0,14439166 ! developmental growth GO:0048589 82 44 0,000 0,12986847 0,14432496 ! maintenance of location in cell GO:0051651 97 44 0,000 0,12986847 0,14425833 ! leukocyte migration GO:0050900 68 45 0,000 0,1326172 0,14724365 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,1326172 0,14717573 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,1326172 0,14710788 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,1326172 0,14704008 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,1326172 0,14697235 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,1326172 0,14690469 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,1326172 0,14683708 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,1326172 0,14676954 ! cell growth GO:0016049 84 45 0,000 0,1326172 0,14670206 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,13535734 0,14966441 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 0,000 0,13535734 0,14959566 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,13535734 0,14952697 ! pigmentation GO:0043473 100 46 0,000 0,13535734 0,14945835 ! positive regulation of protein transport GO:0051222 72 46 0,000 0,13535734 0,14938979 ! positive regulation of defense response GO:0031349 76 47 0,000 0,13808891 0,15233467 ! response to calcium ion GO:0051592 81 47 0,000 0,13808891 0,15226485 ! endosome transport GO:0016197 108 47 0,000 0,13808891 0,1521951 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,13808891 0,15212542 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,13808891 0,15205579 ! JNK cascade GO:0007254 91 47 0,000 0,13808891 0,15198623 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,13808891 0,15191674 ! methylation GO:0032259 90 47 0,000 0,13808891 0,15184731 ! protein homooligomerization GO:0051260 76 47 0,000 0,13808891 0,15177794 ! mitochondrial transport GO:0006839 82 48 0,000 0,14081194 0,15470024 ! Notch signaling pathway GO:0007219 96 48 0,000 0,14081194 0,15462963 ! cellular component disassembly GO:0022411 86 48 0,000 0,14081194 0,15455909 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,14081194 0,15448861 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,14081194 0,1544182 ! activation of caspase activity GO:0006919 84 48 0,000 0,14081194 0,15434785 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,14081194 0,15427756 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,14081194 0,15420734 ! regulation of lymphocyte differentiation GO:0045619 81 48 0,000 0,14081194 0,15413718 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,14352646 0,15703713 ! regulation of action potential GO:0001508 95 49 0,000 0,14352646 0,15696575 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,14352646 0,15689444 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,14352646 0,15682319 ! regulation of ion transport GO:0043269 77 49 0,000 0,14352646 0,156752 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,14352646 0,15668088 ! peptide metabolic process GO:0006518 76 49 0,000 0,14352646 0,15660982 ! response to temperature stimulus GO:0009266 76 49 0,000 0,14352646 0,15653883 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,14352646 0,1564679 ! endocrine system development GO:0035270 104 49 0,000 0,14352646 0,15639704 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,14352646 0,15632624 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,14352646 0,1562555 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,14352646 0,15618483 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,14352646 0,15611422 ! neuromuscular process GO:0050905 99 50 0,000 0,14623249 0,15898571 ! regulation of ossification GO:0030278 117 50 0,000 0,14623249 0,1589139 ! inner ear development GO:0048839 79 50 0,000 0,14623249 0,15884215 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,14623249 0,15877047 ! negative regulation of immune system process GO:0002683 95 50 0,000 0,14623249 0,15869886 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,14893006 0,16155353 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,14893006 0,16148072 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,14893006 0,16140799 ! excretion GO:0007588 83 51 0,000 0,14893006 0,16133531 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,14893006 0,1612627 ! chromatin remodeling GO:0006338 109 51 0,000 0,14893006 0,16119016 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,14893006 0,16111768 ! vesicle organization GO:0016050 107 51 0,000 0,14893006 0,16104527 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,1516192 0,16387951 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,1516192 0,16380593 ! amino acid activation GO:0043038 92 52 0,000 0,1516192 0,1637324 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! synapse organization GO:0050808 85 52 0,000 0,1516192 0,16365895 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,15429993 0,16647786 ! RNA catabolic process GO:0006401 93 53 0,000 0,15429993 0,16640324 ! regulation of translational initiation GO:0006446 82 53 0,000 0,15429993 0,16632869 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,15429993 0,1662542 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,15429993 0,16617978 ! cell maturation GO:0048469 100 53 0,000 0,15429993 0,16610543 ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,15697228 0,16890667 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,15697228 0,16883116 ! cell recognition GO:0008037 85 54 0,000 0,15697228 0,16875572 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,15697228 0,16868035 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,15697228 0,16860505 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,15697228 0,16852981 ! chloride transport GO:0006821 90 55 0,000 0,15963627 0,1713135 ! positive regulation of caspase activity GO:0043280 95 55 0,000 0,15963627 0,17123713 GO:0010952|positive regulation of peptidase activity, ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,15963627 0,17116082 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,15963627 0,17108458 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,15963627 0,1710084 ! aging GO:0007568 103 55 0,000 0,15963627 0,1709323 ! gastrulation GO:0007369 112 55 0,000 0,15963627 0,17085626 ! RNA elongation GO:0006354 79 55 0,000 0,15963627 0,17078029 ! nuclear export GO:0051168 97 55 0,000 0,15963627 0,17070439 ! sensory perception of smell GO:0007608 80 56 0,000 0,16229194 0,17346708 ! skeletal muscle fiber development GO:0048741 111 56 0,000 0,16229194 0,17339005 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,16229194 0,17331309 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,16229194 0,1732362 ! proton transport GO:0015992 94 56 0,000 0,16229194 0,17315938 ! muscle fiber development GO:0048747 112 57 0,000 0,1649393 0,175906 ! regulation of intracellular transport GO:0032386 101 57 0,000 0,1649393 0,17582807 ! maintenance of location GO:0051235 118 57 0,000 0,1649393 0,1757502 ! hydrogen transport GO:0006818 97 58 0,000 0,16757838 0,17848321 ! regulation of endocytosis GO:0030100 91 58 0,000 0,16757838 0,17840424 ! adult behavior GO:0030534 99 58 0,000 0,16757838 0,17832533 ! positive regulation of secretion GO:0051047 95 59 0,000 0,1702092 0,1810448 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,1702092 0,1809648 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,1702092 0,18088487 ! DNA catabolic process GO:0006308 86 59 0,000 0,1702092 0,18080501 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,17283181 0,18350985 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,17283181 0,1834289 ! regulation of heart contraction GO:0008016 110 60 0,000 0,17283181 0,18334803 ! camera-type eye development GO:0043010 116 60 0,000 0,17283181 0,18326722 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,17283181 0,18318649 ! kidney development GO:0001822 122 60 0,000 0,17283181 0,18310582 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,1754462 0,18579382 ! tRNA processing GO:0008033 89 61 0,000 0,1754462 0,18571208 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,1754462 0,18563042 ! ear development GO:0043583 103 62 0,000 0,17805243 0,18830512 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,17805243 0,18822238 ! gonad development GO:0008406 98 62 0,000 0,17805243 0,18813972 ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,1806505 0,19080118 ! detection of external stimulus GO:0009581 91 63 0,000 0,1806505 0,19071746 ! steroid hormone receptor signaling pathway GO:0030518 129 63 0,000 0,1806505 0,19063381 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,18324044 0,19328211 ! cell redox homeostasis GO:0045454 102 64 0,000 0,18324044 0,19319742 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,18324044 0,19311279 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,18324044 0,19302824 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,18324044 0,19294376 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,18582229 0,19557674 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,18582229 0,19549122 ! germ cell development GO:0007281 118 65 0,000 0,18582229 0,19540578 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,18839605 0,19802573 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,18839605 0,19793926 ! extracellular matrix organization GO:0030198 133 66 0,000 0,18839605 0,19785286 ! secondary metabolic process GO:0019748 116 66 0,000 0,18839605 0,19776654 ! developmental maturation GO:0021700 116 66 0,000 0,18839605 0,19768029 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,19096177 0,2002851 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,19096177 0,20019783 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,19096177 0,20011064 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,19096177 0,20002352 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,19096177 0,19993648 ! activation of immune response GO:0002253 105 67 0,000 0,19096177 0,19984951 ! amino acid transport GO:0006865 125 68 0,000 0,19351946 0,20243819 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,19351946 0,20235021 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,19351946 0,20226231 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 0,000 0,19351946 0,20217448 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,19351946 0,20208673 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,19351946 0,20199906 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,19606915 0,20457172 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,19606915 0,20448304 ! urogenital system development GO:0001655 137 69 0,000 0,19606915 0,20439445 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,19606915 0,20430593 ! antigen processing and presentation GO:0019882 104 69 0,000 0,19606915 0,20421748 ! reproductive structure development GO:0048608 113 71 0,000 0,20114463 0,20941323 ! humoral immune response GO:0006959 109 71 0,000 0,20114463 0,20932266 ! B cell activation GO:0042113 160 71 0,000 0,20114463 0,20923216 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,20114463 0,20914174 ! regulation of immune effector process GO:0002697 137 71 0,000 0,20114463 0,2090514 ! acute inflammatory response GO:0002526 113 72 0,000 0,20367047 0,21158512 ! regulation of caspase activity GO:0043281 122 72 0,000 0,20367047 0,2114938 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,20367047 0,21140256 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,20367047 0,2113114 ! learning or memory GO:0007611 147 73 0,000 0,2061884 0,21383159 ! regulation of blood pressure GO:0008217 125 73 0,000 0,2061884 0,21373946 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,2061884 0,21364741 ! axon guidance GO:0007411 139 73 0,000 0,2061884 0,21355544 ! fertilization GO:0009566 90 73 0,000 0,2061884 0,21346355 ! transition metal ion transport GO:0000041 126 74 0,000 0,20869845 0,21596924 ! neurotransmitter transport GO:0006836 123 74 0,000 0,20869845 0,21587639 ! exocytosis GO:0006887 133 74 0,000 0,20869845 0,21578362 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,20869845 0,21569093 ! regulation of endopeptidase activity GO:0052548 125 74 0,000 0,20869845 0,21559832 ! eye development GO:0001654 143 74 0,000 0,20869845 0,21550579 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,21120066 0,21799604 ! phosphoinositide-mediated signaling GO:0048015 131 75 0,000 0,21120066 0,21790256 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,21120066 0,21780916 ! rhythmic process GO:0048511 128 75 0,000 0,21120066 0,21771584 ! lymphocyte differentiation GO:0030098 167 75 0,000 0,21120066 0,2176226 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,21369503 0,22009856 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,21369503 0,22000438 ! defense response to bacterium GO:0042742 89 76 0,000 0,21369503 0,21991028 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,21369503 0,21981626 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,2161816 0,22227903 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,2161816 0,22218408 ! blood coagulation GO:0007596 146 78 0,000 0,21866038 0,22463573 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,21866038 0,22453986 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,22113141 0,22698045 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,22113141 0,22688366 ! regulation of peptidase activity GO:0052547 134 79 0,000 0,22113141 0,22678695 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 0,000 0,22113141 0,22669032 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,22113141 0,22659377 ! response to metal ion GO:0010038 140 80 0,000 0,22359471 0,22902038 ! muscle cell differentiation GO:0042692 159 80 0,000 0,22359471 0,22892292 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,22359471 0,22882555 ! protein import into nucleus GO:0006606 158 80 0,000 0,22359471 0,22872826 ! inorganic anion transport GO:0015698 138 80 0,000 0,22359471 0,22863105 ! T cell activation GO:0042110 168 81 0,000 0,2260503 0,23104376 ! digestion GO:0007586 112 81 0,000 0,2260503 0,23094565 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,2260503 0,23084763 ! nuclear import GO:0051170 161 81 0,000 0,2260503 0,23074969 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,2260503 0,23065183 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,2284982 0,23305073 ! response to drug GO:0042493 143 82 0,000 0,2284982 0,23295198 ! hemostasis GO:0007599 158 84 0,000 0,23337105 0,23781903 ! negative regulation of transport GO:0051051 153 84 0,000 0,23337105 0,23771835 ! regulation of ligase activity GO:0051340 142 84 0,000 0,23337105 0,23761775 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,23337105 0,23751723 ! response to unfolded protein GO:0006986 131 85 0,000 0,23579604 0,23988383 ! nucleosome assembly GO:0006334 122 85 0,000 0,23579604 0,23978245 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,23579604 0,23968114 ! amine biosynthetic process GO:0009309 138 86 0,000 0,23821344 0,24203612 ! response to inorganic substance GO:0010035 153 86 0,000 0,23821344 0,24193395 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,23821344 0,24183187 ! chromatin assembly GO:0031497 124 86 0,000 0,23821344 0,24172988 ! mitochondrion organization GO:0007005 148 86 0,000 0,23821344 0,24162797 ! amine transport GO:0015837 155 86 0,000 0,23821344 0,24152614 ! protein localization in nucleus GO:0034504 176 87 0,000 0,24062327 0,24386672 ! regulation of protein transport GO:0051223 154 87 0,000 0,24062327 0,24376404 GO:0070201|regulation of establishment of protein localization, ! gland development GO:0048732 206 88 0,000 0,24302556 0,24609407 ! regulation of neurological system process GO:0031644 148 88 0,000 0,24302556 0,24599054 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,24302556 0,24588709 ! cellular defense response GO:0006968 114 89 0,000 0,24542033 0,24820569 ! sex differentiation GO:0007548 145 90 0,000 0,24780761 0,25051475 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,24780761 0,25040954 ! sterol metabolic process GO:0016125 152 91 0,000 0,25018741 0,25270819 ! response to protein stimulus GO:0051789 149 91 0,000 0,25018741 0,25260214 ! regulation of defense response GO:0031347 149 92 0,000 0,25255976 0,25489043 ! nucleosome organization GO:0034728 138 92 0,000 0,25255976 0,25478356 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,25255976 0,25467677 ! vitamin metabolic process GO:0006766 139 92 0,000 0,25255976 0,25457008 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,25492468 0,25684623 GO:0010498|proteasomal protein catabolic process, ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,25492468 0,25673871 ! regulation of membrane potential GO:0042391 164 93 0,000 0,25492468 0,25663129 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,2572822 0,25889627 ! female pregnancy GO:0007565 164 94 0,000 0,2572822 0,25878803 ! transcription initiation GO:0006352 153 94 0,000 0,2572822 0,25867989 ! regulation of T cell activation GO:0050863 158 94 0,000 0,2572822 0,25857184 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,26197512 0,26317835 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,26197512 0,26306851 ! positive regulation of immune response GO:0050778 156 96 0,000 0,26197512 0,26295876 ! detection of stimulus GO:0051606 151 96 0,000 0,26197512 0,2628491 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,26431056 0,26508179 ! protein ubiquitination GO:0016567 217 97 0,000 0,26431056 0,26497134 ! hormone metabolic process GO:0042445 157 97 0,000 0,26431056 0,26486098 ! regulation of protein localization GO:0032880 176 97 0,000 0,26431056 0,26475071 ! response to virus GO:0009615 160 98 0,000 0,2666387 0,26697158 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,2666387 0,26686052 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,26895954 0,26907137 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,26895954 0,26895954