pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6798-VanDeVijver-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/vantveer-oligo_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! glucan biosynthetic process GO:0009250 6 6 3,000 2,373E-08 4,374E-05 GO:0005978|glycogen biosynthetic process, ! insulin receptor signaling pathway GO:0008286 17 15 4,000 2,725E-08 2,511E-05 ! positive regulation of cell migration GO:0030335 36 36 5,000 9,325E-08 5,729E-05 ! positive regulation of cell motion GO:0051272 39 39 5,000 1,539E-07 7,092E-05 ! cellular response to insulin stimulus GO:0032869 23 21 4,000 1,793E-07 6,61E-05 ! regulation of cell migration GO:0030334 71 71 6,000 3,064E-07 9,412E-05 ! glucan metabolic process GO:0044042 25 24 4,000 3,691E-07 9,719E-05 GO:0006073|cellular glucan metabolic process, GO:0005977|glycogen metabolic process, ! response to insulin stimulus GO:0032868 28 26 4,000 5,658E-07 1,303E-04 ! regulation of locomotion GO:0040012 79 79 6,000 6,424E-07 1,315E-04 ! regulation of cell motion GO:0051270 79 79 6,000 6,424E-07 1,184E-04 ! energy reserve metabolic process GO:0006112 28 27 4,000 6,91E-07 1,158E-04 ! cellular polysaccharide biosynthetic process GO:0033692 15 15 3,000 2,069E-06 3,177E-04 ! cellular polysaccharide metabolic process GO:0044264 35 34 4,000 2,302E-06 3,264E-04 ! response to peptide hormone stimulus GO:0043434 36 34 4,000 2,302E-06 3,03E-04 ! cellular carbohydrate biosynthetic process GO:0034637 17 17 3,000 3,573E-06 4,39E-04 ! epidermal growth factor receptor signaling pathway GO:0007173 18 18 3,000 4,572E-06 5,266E-04 ! phosphoinositide 3-kinase cascade GO:0014065 6 6 2,000 5,159E-06 5,594E-04 ! cellular response to hormone stimulus GO:0032870 48 46 4,000 1,07E-05 1,095E-03 ! polysaccharide biosynthetic process GO:0000271 25 25 3,000 1,828E-05 1,773E-03 ! positive regulation of transferase activity GO:0051347 91 88 5,000 2,013E-05 1,855E-03 GO:0033674|positive regulation of kinase activity, ! platelet-derived growth factor receptor signaling pathway GO:0048008 9 9 2,000 2,137E-05 1,876E-03 ! protein amino acid autophosphorylation GO:0046777 28 28 3,000 2,916E-05 2,443E-03 ! positive regulation of nucleocytoplasmic transport GO:0046824 11 11 2,000 4,16E-05 3,333E-03 GO:0032388|positive regulation of intracellular transport, ! positive regulation of nitric oxide biosynthetic process GO:0045429 11 11 2,000 4,16E-05 3,195E-03 ! post-Golgi vesicle-mediated transport GO:0006892 12 12 2,000 5,521E-05 4,07E-03 ! polysaccharide metabolic process GO:0005976 69 66 4,000 6,329E-05 4,487E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 13 13 2,000 7,145E-05 4,877E-03 ! positive regulation of epithelial cell proliferation GO:0050679 14 14 2,000 9,052E-05 5,958E-03 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 42 42 3,000 1,491E-04 9,477E-03 ! regulation of smooth muscle cell proliferation GO:0048660 17 17 2,000 1,668E-04 0,01024688 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 45 44 3,000 1,792E-04 0,01065082 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 46 45 3,000 1,957E-04 0,01127078 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 47 46 3,000 2,133E-04 0,01191322 ! positive regulation of ligase activity GO:0051351 47 46 3,000 2,133E-04 0,01156283 ! positive regulation of protein kinase activity GO:0045860 89 86 4,000 2,238E-04 0,01178645 ! heart development GO:0007507 90 87 4,000 2,363E-04 0,01209894 ! regulation of ubiquitin-protein ligase activity GO:0051438 49 48 3,000 2,519E-04 0,01254935 ! positive regulation of MAP kinase activity GO:0043406 50 49 3,000 2,73E-04 0,01324201 ! regulation of ligase activity GO:0051340 50 49 3,000 2,73E-04 0,01290247 ! energy derivation by oxidation of organic compounds GO:0015980 94 92 4,000 3,07E-04 0,01414512 ! mammary gland development GO:0030879 23 21 2,000 3,203E-04 0,01439861 ! carbohydrate biosynthetic process GO:0016051 53 53 3,000 3,702E-04 0,01624581 ! regulation of cell growth GO:0001558 97 96 4,000 3,743E-04 0,01604064 ! positive regulation of glucose metabolic process GO:0010907 5 5 1,000 4,132E-04 0,01730552 ! mRNA stabilization GO:0048255 5 5 1,000 4,132E-04 0,01692096 GO:0043489|RNA stabilization, ! memory GO:0007613 5 5 1,000 4,132E-04 0,01655311 ! insulin-like growth factor receptor signaling pathway GO:0048009 5 5 1,000 4,132E-04 0,01620092 ! indolalkylamine metabolic process GO:0006586 5 5 1,000 4,132E-04 0,0158634 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phospholipase A2 activity GO:0032429 5 5 1,000 4,132E-04 0,01553965 ! actin cytoskeleton reorganization GO:0031532 5 5 1,000 4,132E-04 0,01522886 ! protein heterooligomerization GO:0051291 5 5 1,000 4,132E-04 0,01493026 ! response to amine stimulus GO:0014075 5 5 1,000 4,132E-04 0,01464314 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! peptidyl-lysine modification GO:0018205 5 5 1,000 4,132E-04 0,01436685 ! positive regulation of blood vessel endothelial cell migration GO:0043536 5 5 1,000 4,132E-04 0,0141008 ! B cell receptor signaling pathway GO:0050853 5 5 1,000 4,132E-04 0,01384442 ! response to hormone stimulus GO:0009725 102 100 4,000 4,521E-04 0,01487951 ! regulation of gene-specific transcription GO:0032583 25 25 2,000 5,439E-04 0,01758575 ! regulation of intracellular protein transport GO:0033157 25 25 2,000 5,439E-04 0,01728254 ! peptidyl-amino acid modification GO:0018193 61 59 3,000 5,592E-04 0,01746859 ! N-terminal protein amino acid modification GO:0031365 6 6 1,000 6,172E-04 0,01895684 GO:0018409|peptide or protein amino-terminal blocking, ! virus-host interaction GO:0019048 6 6 1,000 6,172E-04 0,01864607 ! regulation of lipid kinase activity GO:0043550 6 6 1,000 6,172E-04 0,01834532 ! cartilage condensation GO:0001502 7 6 1,000 6,172E-04 0,01805413 ! regulation of positive chemotaxis GO:0050926 6 6 1,000 6,172E-04 0,01777203 GO:0050927|positive regulation of positive chemotaxis, ! positive regulation of transcription factor import into nucleus GO:0042993 6 6 1,000 6,172E-04 0,01749862 ! nerve growth factor receptor signaling pathway GO:0048011 6 6 1,000 6,172E-04 0,01723349 ! ER overload response GO:0006983 6 6 1,000 6,172E-04 0,01697627 ! negative regulation of T cell proliferation GO:0042130 6 6 1,000 6,172E-04 0,01672662 GO:0070667|negative regulation of mast cell proliferation, ! regulation of vascular permeability GO:0043114 6 6 1,000 6,172E-04 0,0164842 ! peptidyl-serine phosphorylation GO:0018105 6 6 1,000 6,172E-04 0,01624872 ! regulation of bone resorption GO:0045124 6 6 1,000 6,172E-04 0,01601986 ! regulation of T cell differentiation in the thymus GO:0033081 6 6 1,000 6,172E-04 0,01579736 ! regulation of cellular carbohydrate catabolic process GO:0043471 6 6 1,000 6,172E-04 0,01558096 GO:0043470|regulation of carbohydrate catabolic process, GO:0006110|regulation of glycolysis, ! sperm-egg recognition GO:0035036 7 6 1,000 6,172E-04 0,01537041 GO:0007339|binding of sperm to zona pellucida, ! regulation of embryonic development GO:0045995 6 6 1,000 6,172E-04 0,01516547 ! localization within membrane GO:0051668 6 6 1,000 6,172E-04 0,01496592 ! proteasomal protein catabolic process GO:0010498 62 61 3,000 6,351E-04 0,01520212 GO:0043161|proteasomal ubiquitin-dependent protein catabolic process, ! regulation of nucleocytoplasmic transport GO:0046822 27 27 2,000 6,854E-04 0,01619455 ! angiogenesis GO:0001525 65 64 3,000 7,623E-04 0,01778486 ! regulation of epithelial cell proliferation GO:0050678 29 29 2,000 8,484E-04 0,01954554 ! positive regulation of protein transport GO:0051222 29 29 2,000 8,484E-04 0,01930424 ! regulation of MAP kinase activity GO:0043405 67 66 3,000 8,566E-04 0,01925166 ! positive regulation of cellular catabolic process GO:0031331 7 7 1,000 8,604E-04 0,0191054 ! visual behavior GO:0007632 7 7 1,000 8,604E-04 0,01887796 GO:0008542|visual learning, ! startle response GO:0001964 7 7 1,000 8,604E-04 0,01865586 ! negative regulation of lymphocyte proliferation GO:0050672 7 7 1,000 8,604E-04 0,01843893 GO:0032945|negative regulation of mononuclear cell proliferation, GO:0070664|negative regulation of leukocyte proliferation, ! positive regulation of carbohydrate metabolic process GO:0045913 7 7 1,000 8,604E-04 0,01822699 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! cranial nerve development GO:0021545 7 7 1,000 8,604E-04 0,01801987 ! autonomic nervous system development GO:0048483 7 7 1,000 8,604E-04 0,0178174 ! cell-cell recognition GO:0009988 8 7 1,000 8,604E-04 0,01761943 ! dopamine metabolic process GO:0042417 7 7 1,000 8,604E-04 0,01742581 ! regulation of mRNA stability GO:0043488 7 7 1,000 8,604E-04 0,0172364 ! T cell receptor signaling pathway GO:0050852 7 7 1,000 8,604E-04 0,01705106 ! negative regulation of T cell activation GO:0050868 7 7 1,000 8,604E-04 0,01686966 ! skeletal system morphogenesis GO:0048705 31 30 2,000 9,384E-04 0,01820489 ! regulation of intracellular transport GO:0032386 31 31 2,000 1,034E-03 0,01985458 ! negative regulation of bone remodeling GO:0046851 8 8 1,000 1,142E-03 0,02170657 ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 8 1,000 1,142E-03 0,02148507 ! positive regulation of endothelial cell migration GO:0010595 8 8 1,000 1,142E-03 0,02126805 ! sex determination GO:0007530 8 8 1,000 1,142E-03 0,02105537 ! peptidyl-serine modification GO:0018209 8 8 1,000 1,142E-03 0,0208469 ! positive regulation of leukocyte migration GO:0002687 8 8 1,000 1,142E-03 0,02064252 ! regulation of RNA stability GO:0043487 8 8 1,000 1,142E-03 0,02044211 ! regulation of generation of precursor metabolites and energy GO:0043467 8 8 1,000 1,142E-03 0,02024555 ! positive regulation of cell projection organization GO:0031346 9 9 1,000 1,463E-03 0,0256749 ! regulation of nitric-oxide synthase activity GO:0050999 9 9 1,000 1,463E-03 0,02543268 ! regulation of postsynaptic membrane potential GO:0060078 9 9 1,000 1,463E-03 0,02519499 ! positive regulation of endothelial cell proliferation GO:0001938 9 9 1,000 1,463E-03 0,02496171 ! response to ethanol GO:0045471 9 9 1,000 1,463E-03 0,0247327 ! positive regulation of protein import into nucleus GO:0042307 9 9 1,000 1,463E-03 0,02450786 ! histone acetylation GO:0016573 9 9 1,000 1,463E-03 0,02428707 ! negative regulation of tissue remodeling GO:0034104 9 9 1,000 1,463E-03 0,02407022 ! regulation of leukocyte migration GO:0002685 9 9 1,000 1,463E-03 0,02385721 ! regulation of blood vessel endothelial cell migration GO:0043535 9 9 1,000 1,463E-03 0,02364793 ! integrin-mediated signaling pathway GO:0007229 36 36 2,000 1,606E-03 0,02573313 ! lung development GO:0030324 38 37 2,000 1,739E-03 0,02763595 ! regulation of glucose metabolic process GO:0010906 10 10 1,000 1,821E-03 0,02868228 ! calcium-independent cell-cell adhesion GO:0016338 10 10 1,000 1,821E-03 0,02843921 ! centrosome cycle GO:0007098 10 10 1,000 1,821E-03 0,02820022 ! neuromuscular junction development GO:0007528 10 10 1,000 1,821E-03 0,02796522 ! nerve development GO:0021675 10 10 1,000 1,821E-03 0,0277341 ! negative regulation of homeostatic process GO:0032845 10 10 1,000 1,821E-03 0,02750677 ! antigen receptor-mediated signaling pathway GO:0050851 10 10 1,000 1,821E-03 0,02728314 ! cell-matrix adhesion GO:0007160 39 38 2,000 1,88E-03 0,02794126 ! blood vessel morphogenesis GO:0048514 84 83 3,000 2,014E-03 0,0297016 ! respiratory tube development GO:0030323 40 39 2,000 2,027E-03 0,02965372 ! respiratory system development GO:0060541 40 39 2,000 2,027E-03 0,02942023 ! protein oligomerization GO:0051259 39 39 2,000 2,027E-03 0,02919038 ! phosphatidylinositol metabolic process GO:0046488 11 11 1,000 2,216E-03 0,03166301 ! signal complex assembly GO:0007172 11 11 1,000 2,216E-03 0,03141944 ! microtubule-based transport GO:0010970 11 11 1,000 2,216E-03 0,0311796 ! protein amino acid acetylation GO:0006473 11 11 1,000 2,216E-03 0,03094339 ! activation of MAPKK activity GO:0000186 12 11 1,000 2,216E-03 0,03071074 ! interaction with host GO:0051701 11 11 1,000 2,216E-03 0,03048155 ! membrane depolarization GO:0051899 11 11 1,000 2,216E-03 0,03025576 ! regulation of monooxygenase activity GO:0032768 11 11 1,000 2,216E-03 0,03003329 ! regulation of cellular carbohydrate metabolic process GO:0010675 11 11 1,000 2,216E-03 0,02981407 GO:0006109|regulation of carbohydrate metabolic process, ! hindbrain development GO:0030902 11 11 1,000 2,216E-03 0,02959803 ! negative regulation of lymphocyte activation GO:0051250 11 11 1,000 2,216E-03 0,02938509 ! cell-substrate adhesion GO:0031589 43 42 2,000 2,512E-03 0,0330695 ! negative regulation of ligase activity GO:0051352 43 42 2,000 2,512E-03 0,03283496 GO:0051444|negative regulation of ubiquitin-protein ligase activity, GO:0051436|negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle, ! glutamate signaling pathway GO:0007215 12 12 1,000 2,648E-03 0,03437381 ! microtubule organizing center organization GO:0031023 12 12 1,000 2,648E-03 0,03413344 GO:0051297|centrosome organization, ! fibroblast growth factor receptor signaling pathway GO:0008543 12 12 1,000 2,648E-03 0,0338964 ! somitogenesis GO:0001756 13 12 1,000 2,648E-03 0,03366263 ! negative regulation of translation GO:0017148 12 12 1,000 2,648E-03 0,03343207 ! homophilic cell adhesion GO:0007156 45 45 2,000 3,063E-03 0,03840123 ! positive regulation of DNA replication GO:0045740 14 13 1,000 3,117E-03 0,03881492 ! positive regulation of smooth muscle cell proliferation GO:0048661 13 13 1,000 3,117E-03 0,03855442 ! phenol metabolic process GO:0018958 13 13 1,000 3,117E-03 0,03829739 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, GO:0009712|catechol metabolic process, ! vasculogenesis GO:0001570 13 13 1,000 3,117E-03 0,03804377 ! negative regulation of protein catabolic process GO:0042177 13 13 1,000 3,117E-03 0,03779348 ! regulation of endothelial cell migration GO:0010594 13 13 1,000 3,117E-03 0,03754646 ! response to endoplasmic reticulum stress GO:0034976 13 13 1,000 3,117E-03 0,03730265 ! positive regulation of locomotion GO:0040017 13 13 1,000 3,117E-03 0,03706199 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, GO:0050920|regulation of chemotaxis, ! negative regulation of leukocyte activation GO:0002695 13 13 1,000 3,117E-03 0,03682441 ! protein tetramerization GO:0051262 13 13 1,000 3,117E-03 0,03658986 ! blood vessel development GO:0001568 95 94 3,000 3,173E-03 0,03701169 ! regulation of membrane potential GO:0042391 46 46 2,000 3,262E-03 0,03780747 ! vasculature development GO:0001944 97 96 3,000 3,424E-03 0,03943876 ! regulation of catabolic process GO:0009894 48 47 2,000 3,468E-03 0,03970247 ! protein amino acid acylation GO:0043543 14 14 1,000 3,621E-03 0,041199 ! vesicle docking GO:0048278 14 14 1,000 3,621E-03 0,04094625 ! immune response-activating cell surface receptor signaling pathway GO:0002429 14 14 1,000 3,621E-03 0,04069658 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of behavior GO:0050795 14 14 1,000 3,621E-03 0,04044993 ! ossification GO:0001503 50 49 2,000 3,905E-03 0,0433561 GO:0060348|bone development, ! gland development GO:0048732 51 49 2,000 3,905E-03 0,04309649 ! skeletal muscle tissue development GO:0007519 50 49 2,000 3,905E-03 0,04283996 GO:0060538|skeletal muscle organ development, ! anterior/posterior pattern formation GO:0009952 51 50 2,000 4,136E-03 0,04509916 ! regulation of transcription factor import into nucleus GO:0042990 15 15 1,000 4,161E-03 0,0451124 ! ER-nuclear signaling pathway GO:0006984 15 15 1,000 4,161E-03 0,04484859 ! negative regulation of cell activation GO:0050866 15 15 1,000 4,161E-03 0,04458784 ! protein homooligomerization GO:0051260 15 15 1,000 4,161E-03 0,04433011 ! response to light stimulus GO:0009416 53 52 2,000 4,621E-03 0,04894323 ! regulation of synaptic plasticity GO:0048167 16 16 1,000 4,736E-03 0,04987636 ! learning GO:0007612 16 16 1,000 4,736E-03 0,04959298 ! cellular response to reactive oxygen species GO:0034614 16 16 1,000 4,736E-03 0,04931279 ! segmentation GO:0035282 17 16 1,000 4,736E-03 0,04903575 ! positive regulation of catabolic process GO:0009896 16 16 1,000 4,736E-03 0,04876181 ! response to hypoxia GO:0001666 53 53 2,000 4,876E-03 0,04992306 ! regulation of protein transport GO:0051223 53 53 2,000 4,876E-03 0,04964724 GO:0070201|regulation of establishment of protein localization, ! response to oxygen levels GO:0070482 55 54 2,000 5,139E-03 0,05204179 ! positive regulation of cell adhesion GO:0045785 17 17 1,000 5,345E-03 0,05383147 ! myelination GO:0042552 17 17 1,000 5,345E-03 0,0535389 ! glucose transport GO:0015758 17 17 1,000 5,345E-03 0,0532495 ! tissue remodeling GO:0048771 17 17 1,000 5,345E-03 0,05296322 ! embryonic skeletal system morphogenesis GO:0048704 17 17 1,000 5,345E-03 0,05267999 ! immune response-activating signal transduction GO:0002757 17 17 1,000 5,345E-03 0,05239978 GO:0002764|immune response-regulating signal transduction, ! cell recognition GO:0008037 18 17 1,000 5,345E-03 0,05212253 ! regulation of oxidoreductase activity GO:0051341 17 17 1,000 5,345E-03 0,0518482 ! regulation of protein localization GO:0032880 58 57 2,000 5,98E-03 0,05770646 ! regulation of cell projection organization GO:0031344 19 18 1,000 5,988E-03 0,05748257 ! regulation of cellular catabolic process GO:0031329 18 18 1,000 5,988E-03 0,05718473 ! membrane docking GO:0022406 18 18 1,000 5,988E-03 0,05688996 ! hexose transport GO:0008645 18 18 1,000 5,988E-03 0,05659822 GO:0015749|monosaccharide transport, ! ensheathment of neurons GO:0007272 18 18 1,000 5,988E-03 0,05630945 GO:0008366|axon ensheathment, ! negative regulation of catabolic process GO:0009895 18 18 1,000 5,988E-03 0,05602362 ! symbiosis, encompassing mutualism through parasitism GO:0044403 18 18 1,000 5,988E-03 0,05574067 ! regulation of endothelial cell proliferation GO:0001936 19 19 1,000 6,665E-03 0,06172872 ! peptidyl-tyrosine phosphorylation GO:0018108 20 19 1,000 6,665E-03 0,06142008 ! cellular response to oxidative stress GO:0034599 19 19 1,000 6,665E-03 0,06111451 ! peripheral nervous system development GO:0007422 19 19 1,000 6,665E-03 0,06081196 ! dorsal/ventral pattern formation GO:0009953 19 19 1,000 6,665E-03 0,0605124 ! regulation of cell shape GO:0008360 21 19 1,000 6,665E-03 0,06021577 ! cytoskeleton-dependent intracellular transport GO:0030705 20 20 1,000 7,375E-03 0,06630452 ! peptidyl-tyrosine modification GO:0018212 21 20 1,000 7,375E-03 0,06598265 ! single fertilization GO:0007338 21 20 1,000 7,375E-03 0,06566389 ! G1/S transition of mitotic cell cycle GO:0000082 21 21 1,000 8,118E-03 0,0719282 ! regulation of protein import into nucleus GO:0042306 21 21 1,000 8,118E-03 0,07158405 ! regulation of action potential in neuron GO:0019228 21 21 1,000 8,118E-03 0,07124317 ! positive regulation of transcription factor activity GO:0051091 22 22 1,000 8,893E-03 0,0776736 GO:0090047|positive regulation of transcription regulator activity, ! positive regulation of DNA metabolic process GO:0051054 23 22 1,000 8,893E-03 0,07730721 ! embryonic skeletal system development GO:0048706 22 22 1,000 8,893E-03 0,07694427 ! negative regulation of protein metabolic process GO:0051248 66 66 2,000 8,979E-03 0,07732572 ! Golgi vesicle transport GO:0048193 67 67 2,000 9,357E-03 0,08020955 ! striated muscle tissue development GO:0014706 69 67 2,000 9,357E-03 0,07983821 ! Ras protein signal transduction GO:0007265 69 67 2,000 9,357E-03 0,07947029 ! positive regulation of growth GO:0045927 23 23 1,000 9,699E-03 0,08199915 ! calcium-mediated signaling GO:0019722 23 23 1,000 9,699E-03 0,08162473 ! cell projection assembly GO:0030031 25 23 1,000 9,699E-03 0,0812537 ! response to radiation GO:0009314 70 68 2,000 9,745E-03 0,08126438 ! regionalization GO:0003002 70 69 2,000 0,01014157 0,08419331 ! regulation of action potential GO:0001508 24 24 1,000 0,01053735 0,08708668 ! glucose homeostasis GO:0042593 24 24 1,000 0,01053735 0,0866979 GO:0033500|carbohydrate homeostasis, ! fertilization GO:0009566 25 24 1,000 0,01053735 0,08631258 ! positive regulation of transport GO:0051050 71 70 2,000 0,0105478 0,08601588 ! muscle tissue development GO:0060537 72 70 2,000 0,0105478 0,08563696 ! regulation of T cell proliferation GO:0042129 25 25 1,000 0,01140634 0,09220128 ! positive regulation of DNA binding GO:0043388 26 25 1,000 0,01140634 0,09179865 ! heart morphogenesis GO:0003007 25 25 1,000 0,01140634 0,09139953 ! negative regulation of immune system process GO:0002683 25 25 1,000 0,01140634 0,09100386 ! positive regulation of binding GO:0051099 27 26 1,000 0,01230587 0,09775741 ! negative regulation of cell migration GO:0030336 26 26 1,000 0,01230587 0,09733785 ! regulation of T cell differentiation GO:0045580 26 26 1,000 0,01230587 0,09692187 ! synapse organization GO:0050808 26 26 1,000 0,01230587 0,09650944 ! learning or memory GO:0007611 28 27 1,000 0,01323551 0,10336035 ! microtubule-based movement GO:0007018 82 78 2,000 0,01413797 0,10994214 ! neuromuscular process GO:0050905 28 28 1,000 0,01419484 0,10992058 ! carbohydrate transport GO:0008643 28 28 1,000 0,01419484 0,10946066 ! histone modification GO:0016570 28 28 1,000 0,01419484 0,10900457 ! regulation of mast cell proliferation GO:0070666 28 28 1,000 0,01419484 0,10855227 ! cartilage development GO:0051216 29 28 1,000 0,01419484 0,10810371 ! positive regulation of cell cycle GO:0045787 29 29 1,000 0,01518347 0,11515692 ! viral reproductive process GO:0022415 29 29 1,000 0,01518347 0,11468497 ! phosphoinositide metabolic process GO:0030384 29 29 1,000 0,01518347 0,11421686 ! regulation of lymphocyte proliferation GO:0050670 29 29 1,000 0,01518347 0,11375257 GO:0032944|regulation of mononuclear cell proliferation, GO:0070663|regulation of leukocyte proliferation, ! regulation of gene expression, epigenetic GO:0040029 29 29 1,000 0,01518347 0,11329203 ! covalent chromatin modification GO:0016569 29 29 1,000 0,01518347 0,11283521 ! response to UV GO:0009411 29 29 1,000 0,01518347 0,11238205 ! MAPKKK cascade GO:0000165 82 81 2,000 0,01564241 0,11531587 ! tube development GO:0035295 83 81 2,000 0,01564241 0,11485645 ! response to reactive oxygen species GO:0000302 31 30 1,000 0,01620097 0,11848569 ! activation of phospholipase C activity GO:0007202 30 30 1,000 0,01620097 0,11801737 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of response to external stimulus GO:0032103 30 30 1,000 0,01620097 0,11755273 ! vascular process in circulatory system GO:0003018 31 30 1,000 0,01620097 0,11709174 ! skeletal muscle fiber development GO:0048741 31 31 1,000 0,01724696 0,12416462 ! positive regulation of phospholipase activity GO:0010518 31 31 1,000 0,01724696 0,12368149 ! regulation of DNA replication GO:0006275 32 31 1,000 0,01724696 0,1232021 ! negative regulation of cell motion GO:0051271 31 31 1,000 0,01724696 0,12272642 ! regulation of cellular localization GO:0060341 86 85 2,000 0,01778425 0,12606296 ! positive regulation of response to stimulus GO:0048584 86 85 2,000 0,01778425 0,12557996 ! muscle fiber development GO:0048747 32 32 1,000 0,01832102 0,1288765 ! regulation of phospholipase activity GO:0010517 32 32 1,000 0,01832102 0,12838647 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 32 32 1,000 0,01832102 0,12790016 ! regulation of lymphocyte differentiation GO:0045619 32 32 1,000 0,01832102 0,12741752 ! positive regulation of lipase activity GO:0060193 32 32 1,000 0,01832102 0,12693851 ! regulation of anatomical structure morphogenesis GO:0022603 90 86 2,000 0,0183441 0,12662238 ! amino acid transport GO:0006865 33 33 1,000 0,01942277 0,13356779 ! activation of protein kinase activity GO:0032147 35 33 1,000 0,01942277 0,13307125 ! regulation of synaptic transmission GO:0050804 33 33 1,000 0,01942277 0,1325784 ! chemotaxis GO:0006935 90 89 2,000 0,02008242 0,13657527 GO:0042330|taxis, ! regulation of angiogenesis GO:0045765 35 34 1,000 0,02055182 0,13925366 ! regulation of bone remodeling GO:0046850 34 34 1,000 0,02055182 0,13874357 ! regulation of protein catabolic process GO:0042176 35 34 1,000 0,02055182 0,13823721 ! regulation of lipid metabolic process GO:0019216 34 34 1,000 0,02055182 0,13773453 ! viral reproduction GO:0016032 34 34 1,000 0,02055182 0,13723549 ! regulation of cyclin-dependent protein kinase activity GO:0000079 35 35 1,000 0,02170777 0,14443109 ! regulation of cell morphogenesis GO:0022604 38 35 1,000 0,02170777 0,14391156 ! positive regulation of phosphorylation GO:0042327 35 35 1,000 0,02170777 0,14339575 ! regulation of tissue remodeling GO:0034103 35 35 1,000 0,02170777 0,14288362 ! positive regulation of immune system process GO:0002684 92 92 2,000 0,02190909 0,14369556 ! positive regulation of phosphorus metabolic process GO:0010562 36 36 1,000 0,02289024 0,14959827 GO:0045937|positive regulation of phosphate metabolic process, ! regulation of transmission of nerve impulse GO:0051969 36 36 1,000 0,02289024 0,14906966 ! regulation of lipase activity GO:0060191 36 36 1,000 0,02289024 0,14854476 ! activation of immune response GO:0002253 36 36 1,000 0,02289024 0,14802355 ! pattern specification process GO:0007389 96 94 2,000 0,02317604 0,14934769 ! regulation of transcription factor activity GO:0051090 38 37 1,000 0,02409886 0,15475329 GO:0090046|regulation of transcription regulator activity, ! negative regulation of protein kinase activity GO:0006469 37 37 1,000 0,02409886 0,15421596 ! response to drug GO:0042493 37 37 1,000 0,02409886 0,15368234 ! adaptive immune response GO:0002250 37 37 1,000 0,02409886 0,1531524 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! exocytosis GO:0006887 40 38 1,000 0,02533324 0,16044387 ! negative regulation of kinase activity GO:0033673 38 38 1,000 0,02533324 0,15989441 ! axon guidance GO:0007411 39 38 1,000 0,02533324 0,15934869 ! regulation of neurological system process GO:0031644 38 38 1,000 0,02533324 0,15880669 ! regulation of homeostatic process GO:0032844 38 38 1,000 0,02533324 0,15826836 ! posttranscriptional regulation of gene expression GO:0010608 98 98 2,000 0,02582803 0,16081437 ! blood circulation GO:0008015 99 98 2,000 0,02582803 0,16027291 GO:0003013|circulatory system process, ! activation of MAPK activity GO:0000187 39 39 1,000 0,02659302 0,16446624 ! cytokine-mediated signaling pathway GO:0019221 39 39 1,000 0,02659302 0,16391619 ! muscle organ development GO:0007517 102 100 2,000 0,02721304 0,16717879 ! negative regulation of transferase activity GO:0051348 40 40 1,000 0,02787783 0,1706938 ! regulation of caspase activity GO:0043281 41 41 1,000 0,02918729 0,17811979 ! regulation of endopeptidase activity GO:0052548 42 42 1,000 0,03052105 0,18564455 ! rRNA transcription GO:0009303 5 5 0,000 0,03228773 0,19574439 ! positive regulation of protein ubiquitination GO:0031398 5 5 0,000 0,03228773 0,19510261 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 5 5 0,000 0,03228773 0,19446502 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 5 5 0,000 0,03228773 0,19383158 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! neuron fate specification GO:0048665 5 5 0,000 0,03228773 0,19320226 ! hemoglobin biosynthetic process GO:0042541 5 5 0,000 0,03228773 0,19257701 ! reproductive cellular process GO:0048610 5 5 0,000 0,03228773 0,19195579 ! negative regulation of blood pressure GO:0045776 6 5 0,000 0,03228773 0,19133857 ! prostate gland development GO:0030850 5 5 0,000 0,03228773 0,1907253 ! metencephalon development GO:0022037 5 5 0,000 0,03228773 0,19011596 ! water transport GO:0006833 5 5 0,000 0,03228773 0,18951049 GO:0042044|fluid transport, ! forebrain regionalization GO:0021871 5 5 0,000 0,03228773 0,18890887 ! DNA synthesis during DNA repair GO:0000731 5 5 0,000 0,03228773 0,18831106 ! positive regulation of B cell proliferation GO:0030890 5 5 0,000 0,03228773 0,18771702 ! glycerol metabolic process GO:0006071 5 5 0,000 0,03228773 0,18712671 ! regulation of cellular amine metabolic process GO:0033238 5 5 0,000 0,03228773 0,18654011 GO:0042053|regulation of dopamine metabolic process, GO:0042069|regulation of catecholamine metabolic process, ! meiotic prophase I GO:0007128 5 5 0,000 0,03228773 0,18595717 GO:0051324|prophase, ! cell volume homeostasis GO:0006884 5 5 0,000 0,03228773 0,18537787 ! regulation of epidermal growth factor receptor activity GO:0007176 5 5 0,000 0,03228773 0,18480216 GO:0010469|regulation of receptor activity, ! regulation of long-term neuronal synaptic plasticity GO:0048169 5 5 0,000 0,03228773 0,18423002 ! filopodium assembly GO:0046847 7 5 0,000 0,03228773 0,1836614 GO:0030035|microspike assembly, ! CTP metabolic process GO:0046036 5 5 0,000 0,03228773 0,18309629 GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0006241|CTP biosynthetic process, ! Golgi to endosome transport GO:0006895 5 5 0,000 0,03228773 0,18253465 ! GTP metabolic process GO:0046039 5 5 0,000 0,03228773 0,18197644 ! establishment of tissue polarity GO:0007164 5 5 0,000 0,03228773 0,18142163 ! positive regulation of cell-cell adhesion GO:0022409 5 5 0,000 0,03228773 0,1808702 ! regulation of neurotransmitter secretion GO:0046928 5 5 0,000 0,03228773 0,18032211 GO:0001956|positive regulation of neurotransmitter secretion, ! neurotransmitter uptake GO:0001504 5 5 0,000 0,03228773 0,17977733 ! social behavior GO:0035176 5 5 0,000 0,03228773 0,17923583 ! macrophage chemotaxis GO:0048246 6 5 0,000 0,03228773 0,17869758 ! 2-oxoglutarate metabolic process GO:0006103 5 5 0,000 0,03228773 0,17816256 ! dopamine receptor signaling pathway GO:0007212 5 5 0,000 0,03228773 0,17763073 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 5 5 0,000 0,03228773 0,17710207 ! membrane hyperpolarization GO:0060081 5 5 0,000 0,03228773 0,17657654 ! response to lipid GO:0033993 5 5 0,000 0,03228773 0,17605413 ! erythrocyte maturation GO:0043249 5 5 0,000 0,03228773 0,17553479 ! hippocampus development GO:0021766 6 5 0,000 0,03228773 0,17501851 ! regulation of carbohydrate biosynthetic process GO:0043255 5 5 0,000 0,03228773 0,17450526 ! glucocorticoid metabolic process GO:0008211 5 5 0,000 0,03228773 0,17399501 ! middle ear morphogenesis GO:0042474 5 5 0,000 0,03228773 0,17348774 ! amyloid precursor protein catabolic process GO:0042987 5 5 0,000 0,03228773 0,17298342 ! mechanosensory behavior GO:0007638 5 5 0,000 0,03228773 0,17248201 ! heart looping GO:0001947 5 5 0,000 0,03228773 0,17198351 ! negative regulation of endocytosis GO:0045806 5 5 0,000 0,03228773 0,17148788 ! response to interferon-gamma GO:0034341 5 5 0,000 0,03228773 0,1709951 ! pseudouridine synthesis GO:0001522 5 5 0,000 0,03228773 0,17050514 ! endocrine pancreas development GO:0031018 5 5 0,000 0,03228773 0,17001799 ! pH reduction GO:0045851 5 5 0,000 0,03228773 0,1695336 GO:0051452|intracellular pH reduction, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 5 5 0,000 0,03228773 0,16905197 ! lipopolysaccharide metabolic process GO:0008653 5 5 0,000 0,03228773 0,16857307 ! positive regulation of chemokine biosynthetic process GO:0045080 5 5 0,000 0,03228773 0,16809688 ! sphingoid biosynthetic process GO:0046520 5 5 0,000 0,03228773 0,16762337 GO:0046513|ceramide biosynthetic process, ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 5 5 0,000 0,03228773 0,16715251 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! thymic T cell selection GO:0045061 5 5 0,000 0,03228773 0,1666843 ! photoreceptor cell maintenance GO:0045494 5 5 0,000 0,03228773 0,1662187 ! adrenal gland development GO:0030325 5 5 0,000 0,03228773 0,1657557 ! regulation of cardiac muscle hypertrophy GO:0010611 5 5 0,000 0,03228773 0,16529526 GO:0010612|regulation of cardiac muscle adaptation, GO:0014743|regulation of muscle hypertrophy, GO:0043502|regulation of muscle adaptation, ! melanocyte differentiation GO:0030318 5 5 0,000 0,03228773 0,16483738 GO:0050931|pigment cell differentiation, ! ovulation GO:0030728 5 5 0,000 0,03228773 0,16438203 ! astrocyte differentiation GO:0048708 5 5 0,000 0,03228773 0,16392919 ! mitochondrial respiratory chain complex assembly GO:0033108 5 5 0,000 0,03228773 0,16347883 GO:0032981|mitochondrial respiratory chain complex I assembly, GO:0010257|NADH dehydrogenase complex assembly, ! pituitary gland development GO:0021983 5 5 0,000 0,03228773 0,16303095 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 5 5 0,000 0,03228773 0,16258551 GO:0033135|regulation of peptidyl-serine phosphorylation, ! tyrosine metabolic process GO:0006570 5 5 0,000 0,03228773 0,16214249 ! cytoskeletal anchoring at plasma membrane GO:0007016 6 5 0,000 0,03228773 0,16170189 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 5 5 0,000 0,03228773 0,16126367 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, GO:0009164|nucleoside catabolic process, ! microtubule nucleation GO:0007020 5 5 0,000 0,03228773 0,16082782 ! regulation of interleukin-6 biosynthetic process GO:0045408 5 5 0,000 0,03228773 0,16039433 ! regulation of interleukin-8 biosynthetic process GO:0045414 5 5 0,000 0,03228773 0,15996316 ! muscle cell migration GO:0014812 5 5 0,000 0,03228773 0,1595343 ! phasic smooth muscle contraction GO:0014821 5 5 0,000 0,03228773 0,15910774 ! central nervous system neuron axonogenesis GO:0021955 6 5 0,000 0,03228773 0,15868345 GO:0021952|central nervous system projection neuron axonogenesis, ! sister chromatid cohesion GO:0007062 5 5 0,000 0,03228773 0,15826142 ! response to ATP GO:0033198 5 5 0,000 0,03228773 0,15784163 ! regulation of type I interferon production GO:0032479 5 5 0,000 0,03228773 0,15742406 ! regulation of appetite GO:0032098 5 5 0,000 0,03228773 0,15700869 GO:0032095|regulation of response to food, ! vesicle fusion GO:0006906 5 5 0,000 0,03228773 0,15659551 ! paraxial mesoderm development GO:0048339 5 5 0,000 0,03228773 0,1561845 ! regulation of the force of heart contraction GO:0002026 5 5 0,000 0,03228773 0,15577564 ! maintenance of protein location in nucleus GO:0051457 5 5 0,000 0,03228773 0,15536892 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,03228773 0,15496431 ! receptor clustering GO:0043113 5 5 0,000 0,03228773 0,15456181 ! neurotransmitter biosynthetic process GO:0042136 6 5 0,000 0,03228773 0,15416139 ! fear response GO:0042596 5 5 0,000 0,03228773 0,15376304 ! lens development in camera-type eye GO:0002088 5 5 0,000 0,03228773 0,15336674 ! retinol metabolic process GO:0042572 5 5 0,000 0,03228773 0,15297248 ! corticosteroid receptor signaling pathway GO:0031958 5 5 0,000 0,03228773 0,15258024 GO:0042921|glucocorticoid receptor signaling pathway, ! temperature homeostasis GO:0001659 5 5 0,000 0,03228773 0,15219001 ! positive regulation of exocytosis GO:0045921 6 5 0,000 0,03228773 0,15180177 ! parturition GO:0007567 5 5 0,000 0,03228773 0,15141551 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,03228773 0,15103121 ! regulation of vascular endothelial growth factor production GO:0010574 5 5 0,000 0,03228773 0,15064885 ! Schwann cell differentiation GO:0014037 5 5 0,000 0,03228773 0,15026842 ! acyl-CoA metabolic process GO:0006637 5 5 0,000 0,03228773 0,14988991 ! wound healing, spreading of epidermal cells GO:0035313 5 5 0,000 0,03228773 0,1495133 ! regulation of gliogenesis GO:0014013 5 5 0,000 0,03228773 0,14913858 GO:0045685|regulation of glial cell differentiation, ! positive regulation of peptide secretion GO:0002793 5 5 0,000 0,03228773 0,14876574 ! response to UV-B GO:0010224 5 5 0,000 0,03228773 0,14839475 ! oligodendrocyte development GO:0014003 5 5 0,000 0,03228773 0,14802561 ! hyaluronan metabolic process GO:0030212 5 5 0,000 0,03228773 0,1476583 ! activated T cell proliferation GO:0050798 5 5 0,000 0,03228773 0,14729281 ! interaction with symbiont GO:0051702 5 5 0,000 0,03228773 0,14692912 ! cellular extravasation GO:0045123 5 5 0,000 0,03228773 0,14656723 ! positive regulation of axonogenesis GO:0050772 5 5 0,000 0,03228773 0,14620711 ! peptidyl-asparagine modification GO:0018196 5 5 0,000 0,03228773 0,14584876 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! positive regulation of phagocytosis GO:0050766 5 5 0,000 0,03228773 0,14549216 ! regulation of insulin receptor signaling pathway GO:0046626 5 5 0,000 0,03228773 0,1451373 ! antigen processing and presentation of exogenous antigen GO:0019884 5 5 0,000 0,03228773 0,14478417 ! enucleate erythrocyte differentiation GO:0043353 6 5 0,000 0,03228773 0,14443275 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 5 5 0,000 0,03228773 0,14408304 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 5 5 0,000 0,03228773 0,14373501 ! synaptic vesicle exocytosis GO:0016079 6 5 0,000 0,03228773 0,14338866 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 5 5 0,000 0,03228773 0,14304398 ! glycosylceramide metabolic process GO:0006677 5 5 0,000 0,03228773 0,14270095 ! neuron recognition GO:0008038 5 5 0,000 0,03228773 0,14235956 ! negative regulation of focal adhesion formation GO:0051895 6 5 0,000 0,03228773 0,1420198 ! decidualization GO:0046697 5 5 0,000 0,03228773 0,14168165 ! hair follicle maturation GO:0048820 5 5 0,000 0,03228773 0,14134512 ! phosphatidylinositol biosynthetic process GO:0006661 5 5 0,000 0,03228773 0,14101018 ! regulation of mitochondrial membrane potential GO:0051881 5 5 0,000 0,03228773 0,14067682 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 0,03228773 0,14034504 GO:0009155|purine deoxyribonucleotide catabolic process, ! regulation of interleukin-12 production GO:0032655 5 5 0,000 0,03228773 0,14001481 ! positive regulation of interleukin-6 production GO:0032755 5 5 0,000 0,03228773 0,13968614 ! positive regulation of monooxygenase activity GO:0032770 5 5 0,000 0,03228773 0,139359 ! postreplication repair GO:0006301 5 5 0,000 0,03228773 0,1390334 ! spinal cord motor neuron differentiation GO:0021522 5 5 0,000 0,03228773 0,13870931 GO:0021517|ventral spinal cord development, ! cellular pigmentation GO:0033059 5 5 0,000 0,03228773 0,13838673 ! histone methylation GO:0016571 5 5 0,000 0,03228773 0,13806565 ! DNA methylation GO:0006306 5 5 0,000 0,03228773 0,13774605 GO:0006305|DNA alkylation, ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,03228773 0,13742793 ! T cell lineage commitment GO:0002360 5 5 0,000 0,03228773 0,13711128 ! positive regulation of immunoglobulin mediated immune response GO:0002891 5 5 0,000 0,03228773 0,13679608 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of interferon-gamma production GO:0032729 5 5 0,000 0,03228773 0,13648233 ! negative regulation of tumor necrosis factor production GO:0032720 5 5 0,000 0,03228773 0,13617001 ! intracellular cholesterol transport GO:0032367 5 5 0,000 0,03228773 0,13585912 GO:0032366|intracellular sterol transport, ! regulation of mast cell activation GO:0033003 5 5 0,000 0,03228773 0,13554965 ! morphogenesis of a polarized epithelium GO:0001738 5 5 0,000 0,03228773 0,13524158 ! regulation of hormone metabolic process GO:0032350 5 5 0,000 0,03228773 0,13493491 ! regulation of transcription from RNA polymerase III promoter GO:0006359 5 5 0,000 0,03228773 0,13462963 ! regulation of inflammatory response to antigenic stimulus GO:0002861 5 5 0,000 0,03228773 0,13432572 ! sterol catabolic process GO:0016127 5 5 0,000 0,03228773 0,13402319 GO:0006707|cholesterol catabolic process, ! negative regulation of oxidoreductase activity GO:0051354 5 5 0,000 0,03228773 0,13372201 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 5 5 0,000 0,03228773 0,13342219 ! detection of biotic stimulus GO:0009595 5 5 0,000 0,03228773 0,1331237 ! regulation of immune response to tumor cell GO:0002837 5 5 0,000 0,03228773 0,13282655 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 5 5 0,000 0,03228773 0,13253072 ! zymogen activation GO:0031638 5 5 0,000 0,03228773 0,13223621 ! positive regulation of interleukin-1 beta secretion GO:0050718 5 5 0,000 0,03228773 0,131943 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 5 5 0,000 0,03228773 0,1316511 GO:0002820|negative regulation of adaptive immune response, ! cellular response to nutrient GO:0031670 5 5 0,000 0,03228773 0,13136047 ! negative regulation of neuroblast proliferation GO:0007406 5 5 0,000 0,03228773 0,13107113 ! peptidyl-histidine modification GO:0018202 5 5 0,000 0,03228773 0,13078307 ! nucleosome positioning GO:0016584 5 5 0,000 0,03228773 0,13049626 ! regulation of isotype switching GO:0045191 5 5 0,000 0,03228773 0,13021071 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 5 5 0,000 0,03228773 0,12992641 ! negative regulation of neurological system process GO:0031645 5 5 0,000 0,03228773 0,12964334 ! regulation of myoblast differentiation GO:0045661 5 5 0,000 0,03228773 0,12936151 ! glutathione biosynthetic process GO:0006750 5 5 0,000 0,03228773 0,1290809 ! NADPH regeneration GO:0006740 5 5 0,000 0,03228773 0,1288015 GO:0006098|pentose-phosphate shunt, ! positive regulation of erythrocyte differentiation GO:0045648 5 5 0,000 0,03228773 0,12852332 ! positive regulation of epidermis development GO:0045684 5 5 0,000 0,03228773 0,12824633 ! positive regulation of leukocyte chemotaxis GO:0002690 5 5 0,000 0,03228773 0,12797053 GO:0002688|regulation of leukocyte chemotaxis, ! musculoskeletal movement GO:0050881 5 5 0,000 0,03228773 0,12769591 GO:0050879|multicellular organismal movement, ! neuromuscular process controlling posture GO:0050884 5 5 0,000 0,03228773 0,12742247 ! sarcomere organization GO:0045214 5 5 0,000 0,03228773 0,1271502 ! regulation of epidermal cell differentiation GO:0045604 5 5 0,000 0,03228773 0,12687909 ! activation of NF-kappaB-inducing kinase activity GO:0007250 5 5 0,000 0,03228773 0,12660914 ! negative regulation of glucose transport GO:0010829 5 5 0,000 0,03228773 0,12634033 GO:0046325|negative regulation of glucose import, ! positive regulation of T-helper cell differentiation GO:0045624 5 5 0,000 0,03228773 0,12607266 GO:0045622|regulation of T-helper cell differentiation, ! oocyte differentiation GO:0009994 5 5 0,000 0,03228773 0,12580612 GO:0048599|oocyte development, ! dopamine biosynthetic process GO:0042416 5 5 0,000 0,03228773 0,12554071 ! regulation of protein homodimerization activity GO:0043496 6 5 0,000 0,03228773 0,12527641 ! spleen development GO:0048536 5 5 0,000 0,03228773 0,12501322 ! male genitalia development GO:0030539 5 5 0,000 0,03228773 0,12475114 ! nicotinamide nucleotide biosynthetic process GO:0019359 5 5 0,000 0,03228773 0,12449016 ! quaternary ammonium group transport GO:0015697 5 5 0,000 0,03228773 0,12423026 ! thyroid hormone metabolic process GO:0042403 5 5 0,000 0,03228773 0,12397145 ! leukocyte mediated cytotoxicity GO:0001909 5 5 0,000 0,03228773 0,12371371 ! positive regulation of viral reproduction GO:0048524 5 5 0,000 0,03228773 0,12345704 ! removal of superoxide radicals GO:0019430 6 5 0,000 0,03228773 0,12320144 ! myeloid cell homeostasis GO:0002262 5 5 0,000 0,03228773 0,12294689 ! regulation of fatty acid oxidation GO:0046320 5 5 0,000 0,03228773 0,12269339 ! regulation of Rac protein signal transduction GO:0035020 5 5 0,000 0,03228773 0,12244094 ! ATP catabolic process GO:0006200 5 5 0,000 0,03228773 0,12218952 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,03228773 0,12193913 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 5 5 0,000 0,03228773 0,12168976 ! blastocyst formation GO:0001825 5 5 0,000 0,03228773 0,12144142 ! regulation of fibrinolysis GO:0051917 5 5 0,000 0,03228773 0,12119408 ! embryonic gut development GO:0048566 5 5 0,000 0,03228773 0,12094775 ! negative regulation of organic acid transport GO:0032891 5 5 0,000 0,03228773 0,12070242 ! pyrimidine base metabolic process GO:0006206 5 5 0,000 0,03228773 0,12045809 ! activation of innate immune response GO:0002218 5 5 0,000 0,03228773 0,12021474 GO:0002758|innate immune response-activating signal transduction, ! catecholamine transport GO:0051937 5 5 0,000 0,03228773 0,11997237 ! negative regulation of blood vessel endothelial cell migration GO:0043537 5 5 0,000 0,03228773 0,11973098 ! regulation of NF-kappaB import into nucleus GO:0042345 5 5 0,000 0,03228773 0,11949055 ! muscle adaptation GO:0043500 5 5 0,000 0,03228773 0,11925109 ! positive regulation of actin filament bundle formation GO:0032233 5 5 0,000 0,03228773 0,11901259 ! embryonic heart tube development GO:0035050 5 5 0,000 0,03228773 0,11877504 ! cardiac cell differentiation GO:0035051 6 5 0,000 0,03228773 0,11853844 ! positive regulation of homeostatic process GO:0032846 5 5 0,000 0,03228773 0,11830277 ! defense response to fungus GO:0050832 5 5 0,000 0,03228773 0,11806805 ! lysogeny GO:0030069 5 5 0,000 0,03228773 0,11783425 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 5 5 0,000 0,03228773 0,11760137 ! positive regulation of smooth muscle contraction GO:0045987 5 5 0,000 0,03228773 0,11736942 ! response to nicotine GO:0035094 5 5 0,000 0,03228773 0,11713838 ! establishment of cell polarity GO:0030010 5 5 0,000 0,03228773 0,11690824 ! mitochondrion localization GO:0051646 5 5 0,000 0,03228773 0,11667901 ! nucleus localization GO:0051647 5 5 0,000 0,03228773 0,11645068 ! regulation of synapse structure and activity GO:0050803 5 5 0,000 0,03228773 0,11622323 ! regulation of DNA binding GO:0051101 47 45 1,000 0,03466455 0,12453562 ! phosphoinositide-mediated signaling GO:0048015 45 45 1,000 0,03466455 0,12429333 ! Wnt receptor signaling pathway GO:0016055 46 45 1,000 0,03466455 0,12405198 ! regulation of peptidase activity GO:0052547 46 46 1,000 0,03609195 0,12890983 ! amine transport GO:0015837 47 47 1,000 0,03754189 0,13382922 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 6 6 0,000 0,03862185 0,13741327 ! axon extension GO:0048675 7 6 0,000 0,03862185 0,1371485 ! oligosaccharide biosynthetic process GO:0009312 6 6 0,000 0,03862185 0,13688475 ! tRNA modification GO:0006400 6 6 0,000 0,03862185 0,13662202 ! somatic diversification of immune receptors via somatic mutation GO:0002566 6 6 0,000 0,03862185 0,13636029 GO:0016446|somatic hypermutation of immunoglobulin genes, ! 'de novo' posttranslational protein folding GO:0051084 6 6 0,000 0,03862185 0,13609956 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 6 6 0,000 0,03862185 0,13583983 ! negative regulation of cellular catabolic process GO:0031330 6 6 0,000 0,03862185 0,13558109 ! regulation of S phase GO:0033261 6 6 0,000 0,03862185 0,13532333 ! myotube differentiation GO:0014902 6 6 0,000 0,03862185 0,13506655 ! regulation of B cell proliferation GO:0030888 6 6 0,000 0,03862185 0,13481074 ! bone remodeling GO:0046849 6 6 0,000 0,03862185 0,1345559 ! N-glycan processing GO:0006491 6 6 0,000 0,03862185 0,13430202 ! glycosaminoglycan catabolic process GO:0006027 6 6 0,000 0,03862185 0,1340491 ! negative regulation of JAK-STAT cascade GO:0046426 6 6 0,000 0,03862185 0,13379713 ! retina development in camera-type eye GO:0060041 6 6 0,000 0,03862185 0,1335461 ! RNA methylation GO:0001510 6 6 0,000 0,03862185 0,13329601 ! regulation of activated T cell proliferation GO:0046006 6 6 0,000 0,03862185 0,13304686 ! succinate metabolic process GO:0006105 7 6 0,000 0,03862185 0,13279864 ! artery development GO:0060840 6 6 0,000 0,03862185 0,13255134 GO:0048844|artery morphogenesis, ! positive regulation of neurotransmitter transport GO:0051590 6 6 0,000 0,03862185 0,13230497 ! bile acid metabolic process GO:0008206 6 6 0,000 0,03862185 0,1320595 ! androgen metabolic process GO:0008209 6 6 0,000 0,03862185 0,13181495 ! estrogen metabolic process GO:0008210 6 6 0,000 0,03862185 0,1315713 ! limbic system development GO:0021761 7 6 0,000 0,03862185 0,13132855 ! cytoplasmic sequestering of transcription factor GO:0042994 6 6 0,000 0,03862185 0,13108669 ! positive regulation of heart contraction GO:0045823 6 6 0,000 0,03862185 0,13084572 ! positive regulation of gene expression, epigenetic GO:0045815 6 6 0,000 0,03862185 0,13060564 ! pathogenesis GO:0009405 6 6 0,000 0,03862185 0,13036643 ! negative regulation of protein amino acid phosphorylation GO:0001933 6 6 0,000 0,03862185 0,1301281 ! positive regulation of cell growth GO:0030307 6 6 0,000 0,03862185 0,12989064 ! ribonucleoside triphosphate catabolic process GO:0009203 6 6 0,000 0,03862185 0,12965405 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! regulation of chemokine biosynthetic process GO:0045073 6 6 0,000 0,03862185 0,12941831 ! inositol phosphate-mediated signaling GO:0048016 6 6 0,000 0,03862185 0,12918343 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 6 6 0,000 0,03862185 0,12894941 ! arginine metabolic process GO:0006525 6 6 0,000 0,03862185 0,12871622 GO:0006527|arginine catabolic process, ! regulation of catecholamine secretion GO:0050433 6 6 0,000 0,03862185 0,12848388 ! oligodendrocyte differentiation GO:0048709 6 6 0,000 0,03862185 0,12825238 ! glutamate catabolic process GO:0006538 7 6 0,000 0,03862185 0,12802171 ! telomere maintenance via telomerase GO:0007004 6 6 0,000 0,03862185 0,12779187 GO:0010833|telomere maintenance via telomere lengthening, ! L-phenylalanine metabolic process GO:0006558 6 6 0,000 0,03862185 0,12756285 GO:0006559|L-phenylalanine catabolic process, ! L-serine metabolic process GO:0006563 6 6 0,000 0,03862185 0,12733465 ! V(D)J recombination GO:0033151 6 6 0,000 0,03862185 0,12710727 ! focal adhesion formation GO:0048041 7 6 0,000 0,03862185 0,1268807 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 0,03862185 0,12665493 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 6 6 0,000 0,03862185 0,12642997 ! negative regulation of endothelial cell migration GO:0010596 6 6 0,000 0,03862185 0,1262058 ! regulation of heart rate GO:0002027 6 6 0,000 0,03862185 0,12598243 ! lipid digestion GO:0044241 6 6 0,000 0,03862185 0,12575984 ! asymmetric protein localization GO:0008105 6 6 0,000 0,03862185 0,12553805 ! retrograde transport, endosome to Golgi GO:0042147 6 6 0,000 0,03862185 0,12531703 ! phagocytosis, engulfment GO:0006911 6 6 0,000 0,03862185 0,12509679 ! Rac protein signal transduction GO:0016601 6 6 0,000 0,03862185 0,12487732 ! regulation of calcium ion transport into cytosol GO:0010522 6 6 0,000 0,03862185 0,12465862 ! ruffle organization GO:0031529 6 6 0,000 0,03862185 0,12444069 ! preassembly of GPI anchor in ER membrane GO:0016254 6 6 0,000 0,03862185 0,12422351 ! retinoic acid metabolic process GO:0042573 6 6 0,000 0,03862185 0,12400709 ! neutral amino acid transport GO:0015804 6 6 0,000 0,03862185 0,12379143 ! L-amino acid transport GO:0015807 6 6 0,000 0,03862185 0,12357651 ! bone mineralization GO:0030282 6 6 0,000 0,03862185 0,12336234 GO:0031214|biomineral formation, ! rRNA modification GO:0000154 6 6 0,000 0,03862185 0,12314891 ! negative regulation of ossification GO:0030279 6 6 0,000 0,03862185 0,12293622 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 6 6 0,000 0,03862185 0,12272426 GO:0002717|positive regulation of natural killer cell mediated immunity, GO:0002715|regulation of natural killer cell mediated immunity, GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 7 6 0,000 0,03862185 0,12251303 ! purine base biosynthetic process GO:0009113 6 6 0,000 0,03862185 0,12230253 ! G1 DNA damage checkpoint GO:0031571 6 6 0,000 0,03862185 0,12209275 ! negative regulation of axonogenesis GO:0050771 7 6 0,000 0,03862185 0,12188368 ! regulation of phagocytosis GO:0050764 6 6 0,000 0,03862185 0,12167534 ! regulation of organ growth GO:0046620 6 6 0,000 0,03862185 0,1214677 ! regulation of circadian rhythm GO:0042752 6 6 0,000 0,03862185 0,12126077 ! positive regulation of T cell mediated immunity GO:0002711 6 6 0,000 0,03862185 0,12105454 ! response to dsRNA GO:0043331 6 6 0,000 0,03862185 0,12084902 ! DNA unwinding during replication GO:0006268 6 6 0,000 0,03862185 0,12064419 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 6 6 0,000 0,03862185 0,12044005 GO:0009147|pyrimidine nucleoside triphosphate metabolic process, ! genitalia development GO:0048806 6 6 0,000 0,03862185 0,12023661 ! sphingomyelin metabolic process GO:0006684 6 6 0,000 0,03862185 0,12003385 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 6 6 0,000 0,03862185 0,11983177 ! positive regulation of B cell differentiation GO:0045579 6 6 0,000 0,03862185 0,11963037 ! multicellular organismal aging GO:0010259 6 6 0,000 0,03862185 0,11942965 ! regulation of focal adhesion formation GO:0051893 7 6 0,000 0,03862185 0,1192296 ! respiratory chain complex IV assembly GO:0008535 6 6 0,000 0,03862185 0,11903022 ! erythrocyte development GO:0048821 6 6 0,000 0,03862185 0,11883151 ! renal water homeostasis GO:0003091 6 6 0,000 0,03862185 0,11863345 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 6 6 0,000 0,03862185 0,11843606 GO:0043372|positive regulation of CD4-positive, alpha beta T cell differentiation, ! ribosomal large subunit biogenesis GO:0042273 6 6 0,000 0,03862185 0,11823932 ! regulation of Rho GTPase activity GO:0032319 6 6 0,000 0,03862185 0,11804324 ! ribosome assembly GO:0042255 6 6 0,000 0,03862185 0,1178478 ! positive regulation of Ras GTPase activity GO:0032320 6 6 0,000 0,03862185 0,11765301 ! diencephalon development GO:0021536 6 6 0,000 0,03862185 0,11745886 ! fucose catabolic process GO:0019317 6 6 0,000 0,03862185 0,11726536 GO:0042355|L-fucose catabolic process, ! nitric oxide metabolic process GO:0046209 6 6 0,000 0,03862185 0,11707249 GO:0006809|nitric oxide biosynthetic process, ! protein sumoylation GO:0016925 6 6 0,000 0,03862185 0,11688025 ! regulation of lipid transport GO:0032368 6 6 0,000 0,03862185 0,11668864 ! regulation of cell division GO:0051302 6 6 0,000 0,03862185 0,11649766 ! positive regulation of interleukin-1 secretion GO:0050716 6 6 0,000 0,03862185 0,11630731 ! cellular metabolic compound salvage GO:0043094 6 6 0,000 0,03862185 0,11611757 ! regulation of T-helper 2 type immune response GO:0002828 6 6 0,000 0,03862185 0,11592846 ! salivary gland morphogenesis GO:0007435 6 6 0,000 0,03862185 0,11573995 ! neuroblast proliferation GO:0007405 6 6 0,000 0,03862185 0,11555206 ! regulation of interleukin-1 beta secretion GO:0050706 6 6 0,000 0,03862185 0,11536478 ! nitric oxide mediated signal transduction GO:0007263 6 6 0,000 0,03862185 0,11517811 ! regulation of glucose transport GO:0010827 6 6 0,000 0,03862185 0,11499204 GO:0046324|regulation of glucose import, ! intestinal absorption GO:0050892 6 6 0,000 0,03862185 0,11480657 ! methionine biosynthetic process GO:0009086 6 6 0,000 0,03862185 0,11462169 ! glutamine family amino acid biosynthetic process GO:0009084 6 6 0,000 0,03862185 0,11443741 ! serine family amino acid biosynthetic process GO:0009070 6 6 0,000 0,03862185 0,11425373 ! thymus development GO:0048538 6 6 0,000 0,03862185 0,11407063 ! lymph node development GO:0048535 6 6 0,000 0,03862185 0,11388812 ! organic cation transport GO:0015695 6 6 0,000 0,03862185 0,11370619 ! negative regulation of BMP signaling pathway GO:0030514 6 6 0,000 0,03862185 0,11352484 ! regulation of RNA splicing GO:0043484 6 6 0,000 0,03862185 0,11334406 ! positive regulation of JNK cascade GO:0046330 7 6 0,000 0,03862185 0,11316387 ! germ cell migration GO:0008354 6 6 0,000 0,03862185 0,11298424 ! establishment or maintenance of apical/basal cell polarity GO:0035088 6 6 0,000 0,03862185 0,11280519 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 6 6 0,000 0,03862185 0,1126267 ! alditol metabolic process GO:0019400 6 6 0,000 0,03862185 0,11244877 ! regulation of synaptic transmission, GABAergic GO:0032228 6 6 0,000 0,03862185 0,11227141 ! regulation of amino acid transport GO:0051955 6 6 0,000 0,03862185 0,1120946 ! maternal placenta development GO:0001893 6 6 0,000 0,03862185 0,11191835 ! negative regulation of immune effector process GO:0002698 6 6 0,000 0,03862185 0,11174266 ! calcium ion transport GO:0006816 48 48 1,000 0,03901403 0,1127004 ! actin filament organization GO:0007015 50 48 1,000 0,03901403 0,11252403 ! glycerophospholipid metabolic process GO:0006650 49 48 1,000 0,03901403 0,11234822 ! divalent metal ion transport GO:0070838 49 49 1,000 0,04050803 0,11646848 ! regulation of DNA metabolic process GO:0051052 51 50 1,000 0,04202355 0,12063769 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 50 50 1,000 0,04202355 0,12045008 ! biogenic amine metabolic process GO:0006576 52 51 1,000 0,04356026 0,12466081 ! positive regulation of immune response GO:0050778 51 51 1,000 0,04356026 0,12446754 ! interphase of mitotic cell cycle GO:0051329 52 51 1,000 0,04356026 0,12427487 GO:0051325|interphase, ! respiratory burst GO:0045730 7 7 0,000 0,04491542 0,12794301 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 7 7 0,000 0,04491542 0,12774556 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 7 7 0,000 0,04491542 0,12754873 ! negative regulation of cell projection organization GO:0031345 8 7 0,000 0,04491542 0,1273525 ! positive regulation of blood pressure GO:0045777 7 7 0,000 0,04491542 0,12715688 ! pteridine and derivative biosynthetic process GO:0042559 7 7 0,000 0,04491542 0,12696185 ! regulation of chemokine production GO:0032642 7 7 0,000 0,04491542 0,12676742 ! double-strand break repair via homologous recombination GO:0000724 7 7 0,000 0,04491542 0,12657359 GO:0000725|recombinational repair, ! positive regulation of GTPase activity GO:0043547 7 7 0,000 0,04491542 0,12638034 ! SMAD protein nuclear translocation GO:0007184 7 7 0,000 0,04491542 0,12618769 ! cellular protein complex disassembly GO:0043624 8 7 0,000 0,04491542 0,12599563 GO:0043241|protein complex disassembly, ! hair follicle morphogenesis GO:0031069 7 7 0,000 0,04491542 0,12580414 ! gene silencing by RNA GO:0031047 7 7 0,000 0,04491542 0,12561324 ! regulation of receptor-mediated endocytosis GO:0048259 7 7 0,000 0,04491542 0,12542292 ! oxaloacetate metabolic process GO:0006107 7 7 0,000 0,04491542 0,12523317 ! regulation of neurotransmitter transport GO:0051588 7 7 0,000 0,04491542 0,125044 ! keratinocyte proliferation GO:0043616 7 7 0,000 0,04491542 0,12485539 ! axis specification GO:0009798 7 7 0,000 0,04491542 0,12466736 ! negative regulation of muscle cell differentiation GO:0051148 7 7 0,000 0,04491542 0,12447989 ! amyloid precursor protein metabolic process GO:0042982 7 7 0,000 0,04491542 0,12429298 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 8 7 0,000 0,04491542 0,12410664 ! positive regulation of lipid metabolic process GO:0045834 7 7 0,000 0,04491542 0,12392085 ! negative regulation of lipid metabolic process GO:0045833 7 7 0,000 0,04491542 0,12373561 ! regulation of interferon-gamma biosynthetic process GO:0045072 7 7 0,000 0,04491542 0,12355093 ! endothelial cell differentiation GO:0045446 7 7 0,000 0,04491542 0,1233668 ! negative regulation of striated muscle development GO:0045843 7 7 0,000 0,04491542 0,12318322 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 7 7 0,000 0,04491542 0,12300019 ! digestive system development GO:0055123 7 7 0,000 0,04491542 0,12281769 GO:0048546|digestive tract morphogenesis, GO:0048547|gut morphogenesis, ! hemoglobin metabolic process GO:0020027 7 7 0,000 0,04491542 0,12263574 ! regulation of exit from mitosis GO:0007096 7 7 0,000 0,04491542 0,12245433 ! protein targeting to ER GO:0045047 8 7 0,000 0,04491542 0,12227345 ! cell differentiation in spinal cord GO:0021515 7 7 0,000 0,04491542 0,12209311 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 7 7 0,000 0,04491542 0,12191329 ! endoderm development GO:0007492 7 7 0,000 0,04491542 0,12173401 ! regulation of defense response to virus GO:0050688 7 7 0,000 0,04491542 0,12155525 ! glycolipid biosynthetic process GO:0009247 7 7 0,000 0,04491542 0,12137702 GO:0006688|glycosphingolipid biosynthetic process, ! regulation of mRNA processing GO:0050684 7 7 0,000 0,04491542 0,12119931 ! response to hexose stimulus GO:0009746 7 7 0,000 0,04491542 0,12102211 GO:0034284|response to monosaccharide stimulus, GO:0009749|response to glucose stimulus, ! membrane protein ectodomain proteolysis GO:0006509 7 7 0,000 0,04491542 0,12084544 GO:0033619|membrane protein proteolysis, ! positive regulation of survival gene product expression GO:0045885 7 7 0,000 0,04491542 0,12066928 ! regulation of skeletal muscle fiber development GO:0048742 7 7 0,000 0,04491542 0,12049363 ! cardiac muscle tissue development GO:0048738 7 7 0,000 0,04491542 0,1203185 ! nucleotide-sugar metabolic process GO:0009225 7 7 0,000 0,04491542 0,12014387 ! complement activation, alternative pathway GO:0006957 7 7 0,000 0,04491542 0,11996975 ! arachidonic acid secretion GO:0050482 7 7 0,000 0,04491542 0,11979613 GO:0032309|icosanoid secretion, ! polyamine biosynthetic process GO:0006596 7 7 0,000 0,04491542 0,11962301 ! response to X-ray GO:0010165 7 7 0,000 0,04491542 0,1194504 ! regulation of intracellular pH GO:0051453 7 7 0,000 0,04491542 0,11927828 ! UV protection GO:0009650 7 7 0,000 0,04491542 0,11910666 ! DNA integration GO:0015074 7 7 0,000 0,04491542 0,11893553 ! myofibril assembly GO:0030239 7 7 0,000 0,04491542 0,11876489 GO:0055002|striated muscle cell development, ! positive regulation of muscle contraction GO:0045933 7 7 0,000 0,04491542 0,11859474 ! negative regulation of muscle contraction GO:0045932 7 7 0,000 0,04491542 0,11842507 ! chondroitin sulfate biosynthetic process GO:0030206 7 7 0,000 0,04491542 0,11825589 GO:0030204|chondroitin sulfate metabolic process, ! regulation of exocytosis GO:0017157 8 7 0,000 0,04491542 0,1180872 ! phosphatidylcholine biosynthetic process GO:0006656 7 7 0,000 0,04491542 0,11791898 ! heparan sulfate proteoglycan metabolic process GO:0030201 7 7 0,000 0,04491542 0,11775125 GO:0015012|heparan sulfate proteoglycan biosynthetic process, ! stem cell development GO:0048864 7 7 0,000 0,04491542 0,11758399 GO:0019827|stem cell maintenance, ! alpha-beta T cell differentiation GO:0046632 7 7 0,000 0,04491542 0,1174172 ! negative regulation of myeloid leukocyte differentiation GO:0002762 7 7 0,000 0,04491542 0,11725089 ! NLS-bearing substrate import into nucleus GO:0006607 7 7 0,000 0,04491542 0,11708504 ! axon cargo transport GO:0008088 7 7 0,000 0,04491542 0,11691967 ! eating behavior GO:0042755 7 7 0,000 0,04491542 0,11675476 ! RNA-dependent DNA replication GO:0006278 7 7 0,000 0,04491542 0,11659032 ! purine nucleoside triphosphate catabolic process GO:0009146 7 7 0,000 0,04491542 0,11642634 ! regulation of interleukin-8 production GO:0032677 7 7 0,000 0,04491542 0,11626282 ! purine ribonucleotide catabolic process GO:0009154 7 7 0,000 0,04491542 0,11609976 ! ribosomal small subunit biogenesis GO:0042274 7 7 0,000 0,04491542 0,11593715 ! protein import into peroxisome matrix GO:0016558 7 7 0,000 0,04491542 0,115775 ! induction of an organ GO:0001759 7 7 0,000 0,04491542 0,1156133 ! leukocyte activation during immune response GO:0002366 7 7 0,000 0,04491542 0,11545206 GO:0002263|cell activation during immune response, ! response to estradiol stimulus GO:0032355 7 7 0,000 0,04491542 0,11529126 ! intracellular lipid transport GO:0032365 7 7 0,000 0,04491542 0,11513091 ! detection of chemical stimulus GO:0009593 8 7 0,000 0,04491542 0,11497101 ! platelet activation GO:0030168 8 7 0,000 0,04491542 0,11481155 ! negative regulation of cytokine secretion GO:0050710 7 7 0,000 0,04491542 0,11465253 ! regulation of interleukin-1 secretion GO:0050704 7 7 0,000 0,04491542 0,11449395 ! natural killer cell activation GO:0030101 7 7 0,000 0,04491542 0,11433581 ! response to gamma radiation GO:0010332 8 7 0,000 0,04491542 0,1141781 ! NADP metabolic process GO:0006739 7 7 0,000 0,04491542 0,11402083 ! neuromuscular synaptic transmission GO:0007274 7 7 0,000 0,04491542 0,113864 ! synaptic transmission, cholinergic GO:0007271 7 7 0,000 0,04491542 0,11370759 ! ubiquinone metabolic process GO:0006743 7 7 0,000 0,04491542 0,11355161 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, GO:0042375|quinone cofactor metabolic process, ! regulation of macrophage differentiation GO:0045649 8 7 0,000 0,04491542 0,11339606 ! positive regulation of acute inflammatory response GO:0002675 7 7 0,000 0,04491542 0,11324094 ! regulation of osteoclast differentiation GO:0045670 7 7 0,000 0,04491542 0,11308624 ! negative regulation of cell-substrate adhesion GO:0010812 8 7 0,000 0,04491542 0,11293196 GO:0001953|negative regulation of cell-matrix adhesion, ! multicellular organismal water homeostasis GO:0050891 7 7 0,000 0,04491542 0,1127781 ! regulation of ATPase activity GO:0043462 7 7 0,000 0,04491542 0,11262466 ! hormone catabolic process GO:0042447 7 7 0,000 0,04491542 0,11247164 ! cAMP biosynthetic process GO:0006171 7 7 0,000 0,04491542 0,11231903 ! oxygen transport GO:0015671 7 7 0,000 0,04491542 0,11216684 ! pyridine nucleotide biosynthetic process GO:0019363 7 7 0,000 0,04491542 0,11201506 ! biogenic amine catabolic process GO:0042402 7 7 0,000 0,04491542 0,11186368 ! regulation of axon extension GO:0030516 7 7 0,000 0,04491542 0,11171272 ! cell killing GO:0001906 7 7 0,000 0,04491542 0,11156216 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 7 7 0,000 0,04491542 0,11141201 ! adult feeding behavior GO:0008343 7 7 0,000 0,04491542 0,11126227 ! pyrimidine nucleotide catabolic process GO:0006244 7 7 0,000 0,04491542 0,11111292 ! positive regulation of protein polymerization GO:0032273 7 7 0,000 0,04491542 0,11096398 ! response to cold GO:0009409 7 7 0,000 0,04491542 0,11081543 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 52 52 1,000 0,04511784 0,11116602 ! sodium ion transport GO:0006814 53 53 1,000 0,04669596 0,11490074 ! regulation of T cell activation GO:0050863 53 53 1,000 0,04669596 0,11474754 ! protein amino acid dephosphorylation GO:0006470 55 54 1,000 0,0482943 0,11851716 ! response to virus GO:0009615 54 54 1,000 0,0482943 0,11835956 ! negative regulation of multicellular organismal process GO:0051241 55 54 1,000 0,0482943 0,11820237 ! microtubule cytoskeleton organization GO:0000226 55 55 1,000 0,04991253 0,12200105 ! regulation of cell adhesion GO:0030155 56 55 1,000 0,04991253 0,12183946 ! regulation of skeletal muscle tissue development GO:0048641 8 8 0,000 0,05116871 0,12474064 ! negative regulation of muscle development GO:0048635 8 8 0,000 0,05116871 0,12457586 ! very-long-chain fatty acid metabolic process GO:0000038 8 8 0,000 0,05116871 0,12441151 ! positive regulation of translation GO:0045727 8 8 0,000 0,05116871 0,12424759 ! positive regulation of cell killing GO:0031343 8 8 0,000 0,05116871 0,12408411 ! superoxide anion generation GO:0042554 8 8 0,000 0,05116871 0,12392106 ! sulfur amino acid biosynthetic process GO:0000097 8 8 0,000 0,05116871 0,12375843 ! cGMP metabolic process GO:0046068 8 8 0,000 0,05116871 0,12359623 GO:0006182|cGMP biosynthetic process, ! thyroid gland development GO:0030878 8 8 0,000 0,05116871 0,12343446 ! 'de novo' protein folding GO:0006458 8 8 0,000 0,05116871 0,1232731 ! dicarboxylic acid transport GO:0006835 8 8 0,000 0,05116871 0,12311217 ! phosphoinositide phosphorylation GO:0046854 8 8 0,000 0,05116871 0,12295166 ! embryonic hindlimb morphogenesis GO:0035116 8 8 0,000 0,05116871 0,12279157 ! zinc ion transport GO:0006829 8 8 0,000 0,05116871 0,12263189 ! embryonic forelimb morphogenesis GO:0035115 8 8 0,000 0,05116871 0,12247263 ! folic acid and derivative biosynthetic process GO:0009396 8 8 0,000 0,05116871 0,12231378 ! regulation of neuronal synaptic plasticity GO:0048168 8 8 0,000 0,05116871 0,12215534 ! cardiac muscle contraction GO:0060048 8 8 0,000 0,05116871 0,12199731 ! lipid localization GO:0010876 8 8 0,000 0,05116871 0,1218397 GO:0019915|lipid storage, ! response to pain GO:0048265 8 8 0,000 0,05116871 0,12168248 ! response to cAMP GO:0051591 8 8 0,000 0,05116871 0,12152568 ! COPI coating of Golgi vesicle GO:0048205 8 8 0,000 0,05116871 0,12136927 GO:0048200|Golgi transport vesicle coating, ! negative regulation of transcription factor import into nucleus GO:0042992 8 8 0,000 0,05116871 0,12121327 ! negative regulation of ion transport GO:0043271 8 8 0,000 0,05116871 0,12105767 ! regulation of response to extracellular stimulus GO:0032104 8 8 0,000 0,05116871 0,12090247 GO:0032107|regulation of response to nutrient levels, ! adult walking behavior GO:0007628 8 8 0,000 0,05116871 0,12074766 ! sensory perception of taste GO:0050909 8 8 0,000 0,05116871 0,12059325 ! organelle fusion GO:0048284 8 8 0,000 0,05116871 0,12043924 ! pancreas development GO:0031016 8 8 0,000 0,05116871 0,12028562 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 8 8 0,000 0,05116871 0,12013239 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! T cell selection GO:0045058 8 8 0,000 0,05116871 0,11997955 ! negative regulation of proteolysis GO:0045861 8 8 0,000 0,05116871 0,1198271 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 8 8 0,000 0,05116871 0,11967503 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 8 8 0,000 0,05116871 0,11952335 ! sperm motility GO:0030317 8 8 0,000 0,05116871 0,11937206 ! regulation of striated muscle contraction GO:0006942 8 8 0,000 0,05116871 0,11922114 ! DNA duplex unwinding GO:0032508 8 8 0,000 0,05116871 0,11907061 GO:0032392|DNA geometric change, ! glycine metabolic process GO:0006544 8 8 0,000 0,05116871 0,11892046 ! ribonucleotide catabolic process GO:0009261 8 8 0,000 0,05116871 0,11877069 ! negative regulation of microtubule depolymerization GO:0007026 8 8 0,000 0,05116871 0,11862129 GO:0031114|regulation of microtubule depolymerization, ! phosphagen metabolic process GO:0006599 8 8 0,000 0,05116871 0,11847227 GO:0006600|creatine metabolic process, ! polyamine metabolic process GO:0006595 8 8 0,000 0,05116871 0,11832362 ! Golgi organization GO:0007030 8 8 0,000 0,05116871 0,11817534 ! cell-cell junction assembly GO:0007043 8 8 0,000 0,05116871 0,11802744 ! regulation of stress fiber formation GO:0051492 9 8 0,000 0,05116871 0,11787991 ! fructose metabolic process GO:0006000 8 8 0,000 0,05116871 0,11773274 ! mannose metabolic process GO:0006013 9 8 0,000 0,05116871 0,11758594 ! NAD metabolic process GO:0019674 8 8 0,000 0,05116871 0,11743951 ! negative regulation of mitotic cell cycle GO:0045930 9 8 0,000 0,05116871 0,11729344 ! plasma membrane fusion GO:0045026 8 8 0,000 0,05116871 0,11714773 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 8 8 0,000 0,05116871 0,11700239 ! response to fungus GO:0009620 8 8 0,000 0,05116871 0,1168574 ! stem cell differentiation GO:0048863 8 8 0,000 0,05116871 0,11671278 ! alpha-beta T cell activation GO:0046631 8 8 0,000 0,05116871 0,11656851 ! positive regulation of myeloid leukocyte differentiation GO:0002763 9 8 0,000 0,05116871 0,1164246 ! embryonic digit morphogenesis GO:0042733 8 8 0,000 0,05116871 0,11628104 ! regulation of cytokine production during immune response GO:0002718 8 8 0,000 0,05116871 0,11613784 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 0,05116871 0,11599499 ! regulation of vasodilation GO:0042312 8 8 0,000 0,05116871 0,11585249 ! vasoconstriction GO:0042310 8 8 0,000 0,05116871 0,11571034 ! regulation of T cell mediated immunity GO:0002709 8 8 0,000 0,05116871 0,11556853 ! muscle cell development GO:0055001 8 8 0,000 0,05116871 0,11542708 ! nucleoside triphosphate catabolic process GO:0009143 8 8 0,000 0,05116871 0,11528597 ! regulation of fatty acid metabolic process GO:0019217 8 8 0,000 0,05116871 0,11514521 ! sensory perception of pain GO:0019233 8 8 0,000 0,05116871 0,11500479 ! gastrulation with mouth forming second GO:0001702 8 8 0,000 0,05116871 0,11486471 ! immunoglobulin production during immune response GO:0002381 8 8 0,000 0,05116871 0,11472497 GO:0002208|somatic diversification of immunoglobulins during immune response, GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! mRNA cleavage GO:0006379 8 8 0,000 0,05116871 0,11458557 ! chromatin silencing GO:0006342 8 8 0,000 0,05116871 0,11444651 ! tissue regeneration GO:0042246 8 8 0,000 0,05116871 0,11430779 ! salivary gland development GO:0007431 8 8 0,000 0,05116871 0,1141694 ! negative regulation of blood coagulation GO:0030195 9 8 0,000 0,05116871 0,11403135 ! T cell homeostasis GO:0043029 8 8 0,000 0,05116871 0,11389363 ! peptide biosynthetic process GO:0043043 9 8 0,000 0,05116871 0,11375624 ! water homeostasis GO:0030104 8 8 0,000 0,05116871 0,11361919 ! cofactor transport GO:0051181 8 8 0,000 0,05116871 0,11348246 ! regulation of acute inflammatory response GO:0002673 8 8 0,000 0,05116871 0,11334606 ! acid secretion GO:0046717 8 8 0,000 0,05116871 0,11320999 ! C21-steroid hormone biosynthetic process GO:0006700 8 8 0,000 0,05116871 0,11307425 ! protein-chromophore linkage GO:0018298 9 8 0,000 0,05116871 0,11293883 ! regulation of immunoglobulin production GO:0002637 8 8 0,000 0,05116871 0,11280374 ! branched chain family amino acid metabolic process GO:0009081 8 8 0,000 0,05116871 0,11266897 ! catecholamine biosynthetic process GO:0042423 8 8 0,000 0,05116871 0,11253452 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 8 8 0,000 0,05116871 0,11240039 ! aromatic compound biosynthetic process GO:0019438 8 8 0,000 0,05116871 0,11226658 ! release of cytochrome c from mitochondria GO:0001836 9 8 0,000 0,05116871 0,11213308 ! regulation of organic acid transport GO:0032890 8 8 0,000 0,05116871 0,11199991 ! positive regulation of calcium ion transport GO:0051928 8 8 0,000 0,05116871 0,11186705 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 8 8 0,000 0,05116871 0,11173451 ! regulation of multi-organism process GO:0043900 8 8 0,000 0,05116871 0,11160228 ! positive regulation of amine transport GO:0051954 8 8 0,000 0,05116871 0,11147036 ! developmental induction GO:0031128 8 8 0,000 0,05116871 0,11133875 GO:0045168|cell-cell signaling involved in cell fate specification, ! peptide hormone secretion GO:0030072 8 8 0,000 0,05116871 0,11120746 ! positive regulation of calcium-mediated signaling GO:0050850 8 8 0,000 0,05116871 0,11107647 ! actin filament polymerization GO:0030041 9 8 0,000 0,05116871 0,11094579 ! cytoplasmic sequestering of protein GO:0051220 8 8 0,000 0,05116871 0,11081542 ! peptide hormone processing GO:0016486 8 8 0,000 0,05116871 0,11068536 ! positive regulation of synaptic transmission GO:0050806 8 8 0,000 0,05116871 0,1105556 ! regulation of steroid biosynthetic process GO:0050810 8 8 0,000 0,05116871 0,11042614 ! reproductive developmental process GO:0003006 56 56 1,000 0,05155035 0,11111964 ! extracellular structure organization GO:0043062 56 56 1,000 0,05155035 0,11098982 ! regulation of binding GO:0051098 60 57 1,000 0,05320743 0,11442392 ! innate immune response GO:0045087 58 58 1,000 0,05488348 0,11789075 ! dephosphorylation GO:0016311 60 59 1,000 0,05657819 0,12138952 ! carboxylic acid transport GO:0046942 59 59 1,000 0,05657819 0,12124837 GO:0015849|organic acid transport, ! cellular aromatic compound metabolic process GO:0006725 60 59 1,000 0,05657819 0,12110755 ! lactation GO:0007595 10 9 0,000 0,05738195 0,12268554 ! embryonic pattern specification GO:0009880 10 9 0,000 0,05738195 0,12254337 ! positive regulation of cell size GO:0045793 9 9 0,000 0,05738195 0,12240154 ! regulation of membrane protein ectodomain proteolysis GO:0051043 9 9 0,000 0,05738195 0,12226004 ! positive regulation of protein complex assembly GO:0031334 9 9 0,000 0,05738195 0,12211886 ! cortical actin cytoskeleton organization GO:0030866 10 9 0,000 0,05738195 0,12197801 ! negative regulation of cell cycle process GO:0010948 9 9 0,000 0,05738195 0,12183748 ! viral genome replication GO:0019079 9 9 0,000 0,05738195 0,12169727 ! phospholipid catabolic process GO:0009395 9 9 0,000 0,05738195 0,12155739 ! copper ion transport GO:0006825 9 9 0,000 0,05738195 0,12141783 ! lipid phosphorylation GO:0046834 9 9 0,000 0,05738195 0,12127859 ! aminoglycan catabolic process GO:0006026 9 9 0,000 0,05738195 0,12113967 ! Golgi vesicle budding GO:0048194 9 9 0,000 0,05738195 0,12100107 ! regulation of cell-cell adhesion GO:0022407 9 9 0,000 0,05738195 0,12086278 ! RNA polyadenylation GO:0043631 9 9 0,000 0,05738195 0,12072481 GO:0006378|mRNA polyadenylation, ! gamma-aminobutyric acid signaling pathway GO:0007214 9 9 0,000 0,05738195 0,12058715 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 9 9 0,000 0,05738195 0,12044981 ! negative regulation of cytokine biosynthetic process GO:0042036 9 9 0,000 0,05738195 0,12031278 ! phospholipid efflux GO:0033700 9 9 0,000 0,05738195 0,12017606 ! response to alkaloid GO:0043279 10 9 0,000 0,05738195 0,12003965 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 9 9 0,000 0,05738195 0,11990355 ! cytokine biosynthetic process GO:0042089 9 9 0,000 0,05738195 0,11976776 GO:0042107|cytokine metabolic process, ! negative regulation of gene expression, epigenetic GO:0045814 9 9 0,000 0,05738195 0,11963228 ! regulation of interleukin-2 biosynthetic process GO:0045076 9 9 0,000 0,05738195 0,1194971 ! pyrimidine ribonucleotide metabolic process GO:0009218 9 9 0,000 0,05738195 0,11936223 ! activation of pro-apoptotic gene products GO:0008633 9 9 0,000 0,05738195 0,11922766 ! methionine metabolic process GO:0006555 9 9 0,000 0,05738195 0,11909339 ! glutamine metabolic process GO:0006541 9 9 0,000 0,05738195 0,11895943 ! cerebral cortex development GO:0021987 9 9 0,000 0,05738195 0,11882577 ! response to osmotic stress GO:0006970 9 9 0,000 0,05738195 0,1186924 ! pigmentation during development GO:0048066 9 9 0,000 0,05738195 0,11855934 ! reverse cholesterol transport GO:0043691 9 9 0,000 0,05738195 0,11842658 ! central nervous system neuron development GO:0021954 10 9 0,000 0,05738195 0,11829411 ! pyrimidine ribonucleoside metabolic process GO:0046131 9 9 0,000 0,05738195 0,11816193 ! nucleobase biosynthetic process GO:0046112 9 9 0,000 0,05738195 0,11803006 ! substrate-bound cell migration GO:0006929 9 9 0,000 0,05738195 0,11789847 ! neurotransmitter metabolic process GO:0042133 11 9 0,000 0,05738195 0,11776718 ! negative regulation of caspase activity GO:0043154 9 9 0,000 0,05738195 0,11763619 ! branching involved in ureteric bud morphogenesis GO:0001658 9 9 0,000 0,05738195 0,11750548 GO:0060675|ureteric bud morphogenesis, ! L-glutamate transport GO:0015813 9 9 0,000 0,05738195 0,11737506 GO:0015800|acidic amino acid transport, ! peptide secretion GO:0002790 9 9 0,000 0,05738195 0,11724494 ! regulation of dephosphorylation GO:0035303 9 9 0,000 0,05738195 0,1171151 ! cotranslational protein targeting to membrane GO:0006613 10 9 0,000 0,05738195 0,11698554 ! positive regulation of alpha-beta T cell differentiation GO:0046638 9 9 0,000 0,05738195 0,11685628 ! ventricular cardiac muscle morphogenesis GO:0055010 9 9 0,000 0,05738195 0,1167273 ! behavioral interaction between organisms GO:0051705 9 9 0,000 0,05738195 0,1165986 ! negative regulation of protein import into nucleus GO:0042308 9 9 0,000 0,05738195 0,11647019 ! DNA replication initiation GO:0006270 9 9 0,000 0,05738195 0,11634206 ! prostaglandin metabolic process GO:0006693 9 9 0,000 0,05738195 0,11621421 GO:0006692|prostanoid metabolic process, ! T cell differentiation in the thymus GO:0033077 9 9 0,000 0,05738195 0,11608664 ! regulation of cellular pH GO:0030641 9 9 0,000 0,05738195 0,11595936 ! DNA fragmentation involved in apoptosis GO:0006309 9 9 0,000 0,05738195 0,11583235 ! regulation of immunoglobulin mediated immune response GO:0002889 9 9 0,000 0,05738195 0,11570561 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 10 9 0,000 0,05738195 0,11557916 ! positive regulation of oxidoreductase activity GO:0051353 9 9 0,000 0,05738195 0,11545298 ! positive regulation of cytokine secretion GO:0050715 9 9 0,000 0,05738195 0,11532708 ! negative regulation of inflammatory response GO:0050728 9 9 0,000 0,05738195 0,11520145 ! negative regulation of protein secretion GO:0050709 9 9 0,000 0,05738195 0,1150761 ! positive regulation of transmission of nerve impulse GO:0051971 9 9 0,000 0,05738195 0,11495101 ! collagen catabolic process GO:0030574 9 9 0,000 0,05738195 0,1148262 ! aromatic amino acid family catabolic process GO:0009074 9 9 0,000 0,05738195 0,11470166 ! purine base metabolic process GO:0006144 9 9 0,000 0,05738195 0,11457739 ! gas transport GO:0015669 9 9 0,000 0,05738195 0,11445339 ! cholesterol efflux GO:0033344 9 9 0,000 0,05738195 0,11432966 ! regulation of leukocyte mediated cytotoxicity GO:0001910 9 9 0,000 0,05738195 0,11420619 ! estrogen receptor signaling pathway GO:0030520 9 9 0,000 0,05738195 0,11408299 ! somatic recombination of immunoglobulin gene segments GO:0016447 9 9 0,000 0,05738195 0,11396006 ! regulation of actin filament bundle formation GO:0032231 10 9 0,000 0,05738195 0,11383739 ! defense response to virus GO:0051607 9 9 0,000 0,05738195 0,11371498 ! regulation of calcium-mediated signaling GO:0050848 9 9 0,000 0,05738195 0,11359284 ! actin filament-based movement GO:0030048 9 9 0,000 0,05738195 0,11347096 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 9 9 0,000 0,05738195 0,11334934 ! negative regulation of cellular protein metabolic process GO:0032269 60 60 1,000 0,05829124 0,11502223 ! protein polymerization GO:0051258 65 60 1,000 0,05829124 0,11489921 ! regulation of protein amino acid phosphorylation GO:0001932 62 61 1,000 0,06002235 0,11818503 ! morphogenesis of an epithelium GO:0002009 63 62 1,000 0,06177121 0,12149876 GO:0060429|epithelium development, ! regulation of cellular component biogenesis GO:0044087 63 62 1,000 0,06177121 0,12136923 ! axonogenesis GO:0007409 66 62 1,000 0,06177121 0,12123997 ! di-, tri-valent inorganic cation transport GO:0015674 63 62 1,000 0,06177121 0,12111099 ! regulation of lymphocyte activation GO:0051249 62 62 1,000 0,06177121 0,12098229 ! protein import into nucleus, docking GO:0000059 10 10 0,000 0,0635554 0,1243446 ! regulation of protein ubiquitination GO:0031396 10 10 0,000 0,0635554 0,12421274 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 10 10 0,000 0,0635554 0,12408115 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 10 10 0,000 0,0635554 0,12394985 ! ER-associated protein catabolic process GO:0030433 10 10 0,000 0,0635554 0,12381883 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of cell killing GO:0031341 10 10 0,000 0,0635554 0,12368808 ! neuron maturation GO:0042551 10 10 0,000 0,0635554 0,12355761 ! pteridine and derivative metabolic process GO:0042558 10 10 0,000 0,0635554 0,12342741 ! positive regulation of anti-apoptosis GO:0045768 10 10 0,000 0,0635554 0,12329748 GO:0045767|regulation of anti-apoptosis, ! cortical cytoskeleton organization GO:0030865 11 10 0,000 0,0635554 0,12316783 ! regulation of lipid biosynthetic process GO:0046890 10 10 0,000 0,0635554 0,12303846 ! reciprocal meiotic recombination GO:0007131 10 10 0,000 0,0635554 0,12290935 ! hormone secretion GO:0046879 10 10 0,000 0,0635554 0,12278051 ! glucosamine metabolic process GO:0006041 10 10 0,000 0,0635554 0,12265195 GO:0006044|N-acetylglucosamine metabolic process, ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 10 10 0,000 0,0635554 0,12252365 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! negative regulation of nucleocytoplasmic transport GO:0046823 10 10 0,000 0,0635554 0,12239562 ! inositol metabolic process GO:0006020 10 10 0,000 0,0635554 0,12226786 ! cAMP metabolic process GO:0046058 10 10 0,000 0,0635554 0,12214037 ! vesicle targeting, to, from or within Golgi GO:0048199 10 10 0,000 0,0635554 0,12201314 ! transcription from RNA polymerase III promoter GO:0006383 10 10 0,000 0,0635554 0,12188617 ! forelimb morphogenesis GO:0035136 10 10 0,000 0,0635554 0,12175947 ! glial cell development GO:0021782 10 10 0,000 0,0635554 0,12163303 ! phototransduction GO:0007602 11 10 0,000 0,0635554 0,12150686 ! auditory receptor cell differentiation GO:0042491 10 10 0,000 0,0635554 0,12138094 ! apoptotic mitochondrial changes GO:0008637 11 10 0,000 0,0635554 0,12125529 ! fat cell differentiation GO:0045444 10 10 0,000 0,0635554 0,1211299 ! myoblast differentiation GO:0045445 10 10 0,000 0,0635554 0,12100476 ! inactivation of MAPK activity GO:0000188 10 10 0,000 0,0635554 0,12087989 ! positive regulation of proteolysis GO:0045862 10 10 0,000 0,0635554 0,12075527 ! response to carbohydrate stimulus GO:0009743 10 10 0,000 0,0635554 0,12063091 ! regulation of survival gene product expression GO:0045884 10 10 0,000 0,0635554 0,1205068 ! induction of apoptosis via death domain receptors GO:0008625 10 10 0,000 0,0635554 0,12038295 ! epidermis morphogenesis GO:0048730 10 10 0,000 0,0635554 0,12025935 ! protein polyubiquitination GO:0000209 10 10 0,000 0,0635554 0,12013601 ! glutamate metabolic process GO:0006536 11 10 0,000 0,0635554 0,12001292 ! plasma membrane organization GO:0007009 10 10 0,000 0,0635554 0,11989008 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 10 10 0,000 0,0635554 0,1197675 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cell-substrate junction assembly GO:0007044 11 10 0,000 0,0635554 0,11964516 ! lysosomal transport GO:0007041 10 10 0,000 0,0635554 0,11952307 ! cellular response to unfolded protein GO:0034620 10 10 0,000 0,0635554 0,11940123 GO:0030968|endoplasmic reticulum unfolded protein response, ! central nervous system neuron differentiation GO:0021953 11 10 0,000 0,0635554 0,11927964 ! purine ribonucleoside metabolic process GO:0046128 10 10 0,000 0,0635554 0,1191583 GO:0042278|purine nucleoside metabolic process, ! vesicle coating GO:0006901 10 10 0,000 0,0635554 0,11903721 ! exocrine system development GO:0035272 10 10 0,000 0,0635554 0,11891636 ! cell structure disassembly during apoptosis GO:0006921 10 10 0,000 0,0635554 0,11879575 ! embryo implantation GO:0007566 11 10 0,000 0,0635554 0,11867539 ! regulation of protein binding GO:0043393 11 10 0,000 0,0635554 0,11855527 ! protein targeting to peroxisome GO:0006625 10 10 0,000 0,0635554 0,1184354 ! protein targeting to mitochondrion GO:0006626 10 10 0,000 0,0635554 0,11831577 GO:0070585|protein localization in mitochondrion, ! regulation of alpha-beta T cell differentiation GO:0046637 10 10 0,000 0,0635554 0,11819638 ! intermediate filament cytoskeleton organization GO:0045104 10 10 0,000 0,0635554 0,11807723 ! protein export from nucleus GO:0006611 10 10 0,000 0,0635554 0,11795832 ! negative regulation of immune response GO:0050777 10 10 0,000 0,0635554 0,11783965 ! cytolysis GO:0019835 10 10 0,000 0,0635554 0,11772122 ! positive regulation of biomineral formation GO:0070169 10 10 0,000 0,0635554 0,11760302 GO:0030501|positive regulation of bone mineralization, ! mismatch repair GO:0006298 10 10 0,000 0,0635554 0,11748507 ! regulation of B cell differentiation GO:0045577 10 10 0,000 0,0635554 0,11736734 ! histone deacetylation GO:0016575 10 10 0,000 0,0635554 0,11724986 ! mRNA splice site selection GO:0006376 11 10 0,000 0,0635554 0,11713261 ! synaptic vesicle transport GO:0048489 11 10 0,000 0,0635554 0,11701559 ! gland morphogenesis GO:0022612 10 10 0,000 0,0635554 0,11689881 ! positive regulation of neurological system process GO:0031646 10 10 0,000 0,0635554 0,11678226 ! sphingolipid biosynthetic process GO:0030148 10 10 0,000 0,0635554 0,11666595 GO:0046467|membrane lipid biosynthetic process, ! sphingolipid catabolic process GO:0030149 10 10 0,000 0,0635554 0,11654986 GO:0046466|membrane lipid catabolic process, ! nerve-nerve synaptic transmission GO:0007270 10 10 0,000 0,0635554 0,11643401 ! regulation of erythrocyte differentiation GO:0045646 10 10 0,000 0,0635554 0,11631838 ! regulation of epidermis development GO:0045682 10 10 0,000 0,0635554 0,11620299 ! folic acid and derivative metabolic process GO:0006760 10 10 0,000 0,0635554 0,11608782 ! negative regulation of neuron differentiation GO:0045665 10 10 0,000 0,0635554 0,11597288 ! aspartate family amino acid biosynthetic process GO:0009067 10 10 0,000 0,0635554 0,11585817 ! regulation of BMP signaling pathway GO:0030510 10 10 0,000 0,0635554 0,11574369 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 10 10 0,000 0,0635554 0,11562943 ! lymphocyte homeostasis GO:0002260 10 10 0,000 0,0635554 0,11551539 ! epithelial to mesenchymal transition GO:0001837 10 10 0,000 0,0635554 0,11540159 ! gut development GO:0048565 10 10 0,000 0,0635554 0,115288 ! embryonic organ morphogenesis GO:0048562 10 10 0,000 0,0635554 0,11517464 ! positive regulation of neuron apoptosis GO:0043525 10 10 0,000 0,0635554 0,1150615 ! mRNA 3'-end processing GO:0031124 10 10 0,000 0,0635554 0,11494859 ! negative regulation of coagulation GO:0050819 11 10 0,000 0,0635554 0,11483589 ! protein stabilization GO:0050821 10 10 0,000 0,0635554 0,11472342 ! glycerolipid metabolic process GO:0046486 65 64 1,000 0,06532101 0,11779513 ! regulation of response to external stimulus GO:0032101 65 64 1,000 0,06532101 0,11767999 ! anion transport GO:0006820 65 65 1,000 0,06712138 0,12080537 ! positive regulation of cellular component organization GO:0051130 65 65 1,000 0,06712138 0,12068751 ! protein secretion GO:0009306 11 11 0,000 0,06968932 0,12518267 ! oligosaccharide metabolic process GO:0009311 11 11 0,000 0,06968932 0,12506078 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 11 11 0,000 0,06968932 0,12493912 ! myeloid leukocyte differentiation GO:0002573 12 11 0,000 0,06968932 0,1248177 ! negative regulation of defense response GO:0031348 11 11 0,000 0,06968932 0,12469652 ! G1 phase of mitotic cell cycle GO:0000080 12 11 0,000 0,06968932 0,12457558 ! determination of bilateral symmetry GO:0009855 11 11 0,000 0,06968932 0,12445486 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! positive regulation of hormone secretion GO:0046887 11 11 0,000 0,06968932 0,12433438 ! skin development GO:0043588 11 11 0,000 0,06968932 0,12421414 ! cellular component assembly involved in morphogenesis GO:0010927 11 11 0,000 0,06968932 0,12409412 ! endothelial cell migration GO:0043542 11 11 0,000 0,06968932 0,12397434 ! peroxisomal transport GO:0043574 11 11 0,000 0,06968932 0,12385479 ! protein amino acid methylation GO:0006479 11 11 0,000 0,06968932 0,12373547 GO:0008213|protein amino acid alkylation, ! heart contraction GO:0060047 11 11 0,000 0,06968932 0,12361638 GO:0003015|heart process, ! detection of light stimulus involved in sensory perception GO:0050962 12 11 0,000 0,06968932 0,12349752 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 11 11 0,000 0,06968932 0,12337888 ! T cell proliferation GO:0042098 11 11 0,000 0,06968932 0,12326048 ! regulation of transmembrane transporter activity GO:0022898 11 11 0,000 0,06968932 0,1231423 GO:0032412|regulation of ion transmembrane transporter activity, GO:0032409|regulation of transporter activity, ! negative regulation of endothelial cell proliferation GO:0001937 11 11 0,000 0,06968932 0,12302435 ! regulation of viral genome replication GO:0045069 11 11 0,000 0,06968932 0,12290662 ! spinal cord development GO:0021510 11 11 0,000 0,06968932 0,12278912 ! smooth muscle contraction GO:0006939 11 11 0,000 0,06968932 0,12267184 ! cellular response to starvation GO:0009267 11 11 0,000 0,06968932 0,12255479 ! cellular macromolecular complex disassembly GO:0034623 12 11 0,000 0,06968932 0,12243796 ! digestive system process GO:0022600 11 11 0,000 0,06968932 0,12232135 ! mitotic spindle organization GO:0007052 11 11 0,000 0,06968932 0,12220497 ! fucose metabolic process GO:0006004 11 11 0,000 0,06968932 0,1220888 ! membrane budding GO:0006900 11 11 0,000 0,06968932 0,12197286 ! apoptotic nuclear changes GO:0030262 11 11 0,000 0,06968932 0,12185713 ! monoamine transport GO:0015844 11 11 0,000 0,06968932 0,12174163 ! regulation of cellular ketone metabolic process GO:0010565 11 11 0,000 0,06968932 0,12162634 ! response to lipopolysaccharide GO:0032496 11 11 0,000 0,06968932 0,12151128 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 11 11 0,000 0,06968932 0,12139643 ! body fluid secretion GO:0007589 11 11 0,000 0,06968932 0,12128179 ! G1/S transition checkpoint GO:0031575 12 11 0,000 0,06968932 0,12116738 ! positive regulation of alpha-beta T cell activation GO:0046635 11 11 0,000 0,06968932 0,12105317 ! intermediate filament-based process GO:0045103 11 11 0,000 0,06968932 0,12093919 ! cardiac muscle tissue morphogenesis GO:0055008 11 11 0,000 0,06968932 0,12082542 GO:0060415|muscle tissue morphogenesis, ! regulation of interleukin-2 production GO:0032663 11 11 0,000 0,06968932 0,12071186 ! regulation of ARF GTPase activity GO:0032312 11 11 0,000 0,06968932 0,12059851 ! oogenesis GO:0048477 11 11 0,000 0,06968932 0,12048538 ! negative regulation of angiogenesis GO:0016525 11 11 0,000 0,06968932 0,12037246 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 11 11 0,000 0,06968932 0,12025976 ! vitamin transport GO:0051180 11 11 0,000 0,06968932 0,12014726 ! muscle maintenance GO:0046716 12 11 0,000 0,06968932 0,12003497 ! vitamin A metabolic process GO:0006776 11 11 0,000 0,06968932 0,11992289 ! steroid catabolic process GO:0006706 11 11 0,000 0,06968932 0,11981102 ! endocrine process GO:0050886 11 11 0,000 0,06968932 0,11969936 GO:0001990|regulation of systemic arterial blood pressure by hormone, ! aromatic amino acid family metabolic process GO:0009072 11 11 0,000 0,06968932 0,11958791 ! proximal/distal pattern formation GO:0009954 11 11 0,000 0,06968932 0,11947667 ! somatic diversification of immunoglobulins GO:0016445 11 11 0,000 0,06968932 0,11936563 ! RNA 3'-end processing GO:0031123 11 11 0,000 0,06968932 0,1192548 ! cell morphogenesis involved in neuron differentiation GO:0048667 72 67 1,000 0,07077161 0,1209945 GO:0048812|neuron projection morphogenesis, GO:0048858|cell projection morphogenesis, ! regulation of translation GO:0006417 69 69 1,000 0,07448596 0,12722672 ! sensory perception of sound GO:0007605 71 69 1,000 0,07448596 0,12710892 GO:0050954|sensory perception of mechanical stimulus, ! regulation of leukocyte activation GO:0002694 69 69 1,000 0,07448596 0,12699133 ! positive regulation of protein catabolic process GO:0045732 12 12 0,000 0,07578395 0,12908485 ! translational initiation GO:0006413 12 12 0,000 0,07578395 0,12896566 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 12 12 0,000 0,07578395 0,12884669 ! positive regulation of angiogenesis GO:0045766 12 12 0,000 0,07578395 0,12872794 ! initiation of viral infection GO:0019059 12 12 0,000 0,07578395 0,1286094 ! DNA catabolic process, endonucleolytic GO:0000737 12 12 0,000 0,07578395 0,12849109 ! iron ion transport GO:0006826 13 12 0,000 0,07578395 0,12837299 ! phosphatidylcholine metabolic process GO:0046470 12 12 0,000 0,07578395 0,12825511 ! amino sugar metabolic process GO:0006040 12 12 0,000 0,07578395 0,12813744 ! protein amino acid ADP-ribosylation GO:0006471 12 12 0,000 0,07578395 0,12801999 ! heterophilic cell adhesion GO:0007157 12 12 0,000 0,07578395 0,12790276 ! collagen metabolic process GO:0032963 12 12 0,000 0,07578395 0,12778574 ! hindlimb morphogenesis GO:0035137 12 12 0,000 0,07578395 0,12766893 ! xenobiotic metabolic process GO:0006805 12 12 0,000 0,07578395 0,12755234 ! C21-steroid hormone metabolic process GO:0008207 13 12 0,000 0,07578395 0,12743596 ! regulation of muscle cell differentiation GO:0051147 13 12 0,000 0,07578395 0,12731979 ! cellular response to hydrogen peroxide GO:0070301 12 12 0,000 0,07578395 0,12720384 GO:0042744|hydrogen peroxide catabolic process, ! negative regulation of peptidase activity GO:0010466 12 12 0,000 0,07578395 0,12708809 ! actomyosin structure organization GO:0031032 12 12 0,000 0,07578395 0,12697256 ! positive regulation of endocytosis GO:0045807 12 12 0,000 0,07578395 0,12685723 ! retinoid metabolic process GO:0001523 12 12 0,000 0,07578395 0,12674212 GO:0016101|diterpenoid metabolic process, ! mitotic chromosome condensation GO:0007076 12 12 0,000 0,07578395 0,12662721 ! positive regulation of innate immune response GO:0045089 12 12 0,000 0,07578395 0,12651251 ! GPI anchor biosynthetic process GO:0006506 12 12 0,000 0,07578395 0,12639802 GO:0006505|GPI anchor metabolic process, ! glycoprotein catabolic process GO:0006516 13 12 0,000 0,07578395 0,12628374 ! acute-phase response GO:0006953 12 12 0,000 0,07578395 0,12616966 ! deoxyribonucleotide catabolic process GO:0009264 12 12 0,000 0,07578395 0,12605579 ! vacuolar transport GO:0007034 12 12 0,000 0,07578395 0,12594212 ! polysaccharide catabolic process GO:0000272 12 12 0,000 0,07578395 0,12582866 ! vesicle docking during exocytosis GO:0006904 12 12 0,000 0,07578395 0,1257154 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 12 12 0,000 0,07578395 0,12560235 ! barbed-end actin filament capping GO:0051016 12 12 0,000 0,07578395 0,1254895 GO:0051693|actin filament capping, ! osteoblast differentiation GO:0001649 12 12 0,000 0,07578395 0,12537685 ! male gonad development GO:0008584 12 12 0,000 0,07578395 0,12526441 ! regulation of insulin secretion GO:0050796 12 12 0,000 0,07578395 0,12515216 ! regulation of alpha-beta T cell activation GO:0046634 12 12 0,000 0,07578395 0,12504012 ! renal system process GO:0003014 12 12 0,000 0,07578395 0,12492828 ! regulation of tumor necrosis factor production GO:0032680 12 12 0,000 0,07578395 0,12481663 ! regulation of steroid metabolic process GO:0019218 12 12 0,000 0,07578395 0,12470519 ! regulation of interleukin-6 production GO:0032675 12 12 0,000 0,07578395 0,12459395 ! pallium development GO:0021543 13 12 0,000 0,07578395 0,1244829 ! cell fate determination GO:0001709 12 12 0,000 0,07578395 0,12437205 ! regulation of chromosome organization GO:0033044 12 12 0,000 0,07578395 0,1242614 ! positive regulation of multicellular organism growth GO:0040018 12 12 0,000 0,07578395 0,12415094 ! G1 phase GO:0051318 13 12 0,000 0,07578395 0,12404069 ! regulation of response to biotic stimulus GO:0002831 12 12 0,000 0,07578395 0,12393062 ! positive regulation of adaptive immune response GO:0002821 12 12 0,000 0,07578395 0,12382076 ! detection of light stimulus GO:0009583 13 12 0,000 0,07578395 0,12371108 ! synaptogenesis GO:0007416 12 12 0,000 0,07578395 0,1236016 ! fat-soluble vitamin metabolic process GO:0006775 12 12 0,000 0,07578395 0,12349232 ! hormone transport GO:0009914 12 12 0,000 0,07578395 0,12338323 ! neurotransmitter secretion GO:0007269 14 12 0,000 0,07578395 0,12327433 ! heme biosynthetic process GO:0006783 12 12 0,000 0,07578395 0,12316562 ! spermatid differentiation GO:0048515 13 12 0,000 0,07578395 0,1230571 GO:0007286|spermatid development, ! aromatic compound catabolic process GO:0019439 13 12 0,000 0,07578395 0,12294878 ! pyrimidine nucleotide biosynthetic process GO:0006221 12 12 0,000 0,07578395 0,12284064 ! neural tube closure GO:0001843 13 12 0,000 0,07578395 0,1227327 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! regulation of mitotic metaphase/anaphase transition GO:0030071 13 12 0,000 0,07578395 0,12262495 ! regulation of microtubule polymerization or depolymerization GO:0031110 12 12 0,000 0,07578395 0,12251738 ! cellular monovalent inorganic cation homeostasis GO:0030004 12 12 0,000 0,07578395 0,12241 ! cell part morphogenesis GO:0032990 75 70 1,000 0,0763665 0,12324296 ! wound healing GO:0042060 74 70 1,000 0,0763665 0,12313513 ! negative regulation of signal transduction GO:0009968 71 71 1,000 0,07826224 0,12608156 ! regulation of cell activation GO:0050865 71 71 1,000 0,07826224 0,12597145 ! secretion by cell GO:0032940 75 72 1,000 0,08017292 0,12893429 ! positive regulation of hydrolase activity GO:0051345 72 72 1,000 0,08017292 0,12882188 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 13 13 0,000 0,08183953 0,13138523 GO:0016444|somatic cell DNA recombination, ! negative regulation of actin filament polymerization GO:0030837 13 13 0,000 0,08183953 0,13127088 ! G2/M transition of mitotic cell cycle GO:0000086 13 13 0,000 0,08183953 0,13115674 ! gluconeogenesis GO:0006094 13 13 0,000 0,08183953 0,13104279 ! negative regulation of hormone secretion GO:0046888 13 13 0,000 0,08183953 0,13092903 ! 2'-deoxyribonucleotide metabolic process GO:0009394 13 13 0,000 0,08183953 0,13081548 GO:0019692|deoxyribose phosphate metabolic process, ! intra-Golgi vesicle-mediated transport GO:0006891 13 13 0,000 0,08183953 0,13070212 ! glycosaminoglycan biosynthetic process GO:0006024 13 13 0,000 0,08183953 0,13058896 ! positive regulation of JAK-STAT cascade GO:0046427 13 13 0,000 0,08183953 0,13047599 ! regeneration GO:0031099 13 13 0,000 0,08183953 0,13036322 ! keratinization GO:0031424 13 13 0,000 0,08183953 0,13025064 ! post-embryonic development GO:0009791 14 13 0,000 0,08183953 0,13013826 ! negative regulation of protein modification process GO:0031400 13 13 0,000 0,08183953 0,13002607 ! patterning of blood vessels GO:0001569 13 13 0,000 0,08183953 0,12991408 ! regulation of DNA recombination GO:0000018 13 13 0,000 0,08183953 0,12980228 ! regulation of innate immune response GO:0045088 13 13 0,000 0,08183953 0,12969067 ! mitochondrial membrane organization GO:0007006 13 13 0,000 0,08183953 0,12957925 ! negative regulation of DNA replication GO:0008156 13 13 0,000 0,08183953 0,12946802 ! multicellular organismal macromolecule metabolic process GO:0044259 13 13 0,000 0,08183953 0,12935699 ! response to corticosteroid stimulus GO:0031960 13 13 0,000 0,08183953 0,12924614 GO:0051384|response to glucocorticoid stimulus, ! multicellular organismal catabolic process GO:0044243 13 13 0,000 0,08183953 0,12913548 ! autophagy GO:0006914 13 13 0,000 0,08183953 0,12902502 ! receptor metabolic process GO:0043112 14 13 0,000 0,08183953 0,12891474 ! actin filament bundle formation GO:0051017 13 13 0,000 0,08183953 0,12880465 ! ureteric bud development GO:0001657 13 13 0,000 0,08183953 0,12869475 ! cell aging GO:0007569 13 13 0,000 0,08183953 0,12858504 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 13 13 0,000 0,08183953 0,12847551 ! coenzyme catabolic process GO:0009109 13 13 0,000 0,08183953 0,12836617 GO:0046356|acetyl-CoA catabolic process, GO:0006099|tricarboxylic acid cycle, ! negative regulation of protein kinase cascade GO:0010741 13 13 0,000 0,08183953 0,12825701 ! purine nucleoside monophosphate metabolic process GO:0009126 13 13 0,000 0,08183953 0,12814804 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of peptide secretion GO:0002791 13 13 0,000 0,08183953 0,12803926 ! regulation of viral reproduction GO:0050792 13 13 0,000 0,08183953 0,12793066 ! nucleobase metabolic process GO:0009112 13 13 0,000 0,08183953 0,12782224 ! regulation of axonogenesis GO:0050770 14 13 0,000 0,08183953 0,12771401 ! positive regulation of neurogenesis GO:0050769 13 13 0,000 0,08183953 0,12760596 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 14 13 0,000 0,08183953 0,12749809 ! nucleotide-excision repair, DNA gap filling GO:0006297 13 13 0,000 0,08183953 0,12739041 ! vasodilation GO:0042311 14 13 0,000 0,08183953 0,12728291 ! positive regulation of leukocyte mediated immunity GO:0002705 13 13 0,000 0,08183953 0,12717559 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 13 13 0,000 0,08183953 0,12706845 ! glycosphingolipid metabolic process GO:0006687 13 13 0,000 0,08183953 0,12696149 GO:0006664|glycolipid metabolic process, ! neural crest cell migration GO:0001755 14 13 0,000 0,08183953 0,12685471 ! neutrophil chemotaxis GO:0030593 14 13 0,000 0,08183953 0,12674811 ! long-chain fatty acid transport GO:0015909 13 13 0,000 0,08183953 0,12664168 ! immunoglobulin production GO:0002377 13 13 0,000 0,08183953 0,12653544 GO:0002440|production of molecular mediator of immune response, ! negative regulation of Wnt receptor signaling pathway GO:0030178 13 13 0,000 0,08183953 0,12642938 ! negative regulation of intracellular transport GO:0032387 13 13 0,000 0,08183953 0,12632349 ! cell-cell junction organization GO:0045216 13 13 0,000 0,08183953 0,12621778 ! regulation of cell-substrate adhesion GO:0010810 14 13 0,000 0,08183953 0,12611225 GO:0001952|regulation of cell-matrix adhesion, ! negative regulation of myeloid cell differentiation GO:0045638 13 13 0,000 0,08183953 0,12600689 ! response to cytokine stimulus GO:0034097 13 13 0,000 0,08183953 0,12590171 ! activation of JUN kinase activity GO:0007257 13 13 0,000 0,08183953 0,1257967 ! terpenoid metabolic process GO:0006721 13 13 0,000 0,08183953 0,12569187 ! alkene biosynthetic process GO:0043450 13 13 0,000 0,08183953 0,12558722 GO:0019370|leukotriene biosynthetic process, ! purine nucleotide catabolic process GO:0006195 13 13 0,000 0,08183953 0,12548273 ! porphyrin biosynthetic process GO:0006779 13 13 0,000 0,08183953 0,12537843 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of cytokine production GO:0001818 13 13 0,000 0,08183953 0,12527429 ! camera-type eye morphogenesis GO:0048593 13 13 0,000 0,08183953 0,12517033 ! pyrimidine nucleoside metabolic process GO:0006213 13 13 0,000 0,08183953 0,12506654 ! blastocyst development GO:0001824 13 13 0,000 0,08183953 0,12496292 ! telomere organization GO:0032200 13 13 0,000 0,08183953 0,12485948 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 13 13 0,000 0,08183953 0,1247562 ! regulation of amine transport GO:0051952 13 13 0,000 0,08183953 0,1246531 ! tissue homeostasis GO:0001894 13 13 0,000 0,08183953 0,12455016 GO:0048871|multicellular organismal homeostasis, ! inner ear receptor cell differentiation GO:0060113 13 13 0,000 0,08183953 0,1244474 ! response to oxidative stress GO:0006979 76 75 1,000 0,08599195 0,13065389 ! neuron fate commitment GO:0048663 14 14 0,000 0,0878563 0,13337658 ! sulfur amino acid metabolic process GO:0000096 14 14 0,000 0,0878563 0,13326681 ! regulation of interferon-gamma production GO:0032649 14 14 0,000 0,0878563 0,13315721 ! pyruvate metabolic process GO:0006090 14 14 0,000 0,0878563 0,1330478 ! cellular aldehyde metabolic process GO:0006081 14 14 0,000 0,0878563 0,13293856 ! acetyl-CoA metabolic process GO:0006084 14 14 0,000 0,0878563 0,13282951 ! cellular iron ion homeostasis GO:0006879 14 14 0,000 0,0878563 0,13272063 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 14 14 0,000 0,0878563 0,13261193 ! regulation of neuron projection development GO:0010975 15 14 0,000 0,0878563 0,13250341 ! protein amino acid deacetylation GO:0006476 14 14 0,000 0,0878563 0,13239507 ! aminoglycan biosynthetic process GO:0006023 14 14 0,000 0,0878563 0,1322869 ! superoxide metabolic process GO:0006801 15 14 0,000 0,0878563 0,13217891 ! macromolecular complex disassembly GO:0032984 15 14 0,000 0,0878563 0,1320711 ! calcium-dependent cell-cell adhesion GO:0016339 14 14 0,000 0,0878563 0,13196346 ! mechanoreceptor differentiation GO:0042490 14 14 0,000 0,0878563 0,131856 ! isoprenoid biosynthetic process GO:0008299 14 14 0,000 0,0878563 0,13174871 ! hair cycle GO:0042633 14 14 0,000 0,0878563 0,1316416 GO:0022404|molting cycle process, GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042303|molting cycle, ! negative regulation of epithelial cell proliferation GO:0050680 14 14 0,000 0,0878563 0,13153466 ! response to retinoic acid GO:0032526 14 14 0,000 0,0878563 0,1314279 GO:0033189|response to vitamin A, ! multicellular organismal response to stress GO:0033555 14 14 0,000 0,0878563 0,13132131 ! lysosome organization GO:0007040 14 14 0,000 0,0878563 0,13121489 ! actin polymerization or depolymerization GO:0008154 15 14 0,000 0,0878563 0,13110864 ! D-ribose metabolic process GO:0006014 14 14 0,000 0,0878563 0,13100256 ! negative regulation of phosphorus metabolic process GO:0010563 14 14 0,000 0,0878563 0,13089666 GO:0045936|negative regulation of phosphate metabolic process, ! peptide transport GO:0015833 14 14 0,000 0,0878563 0,13079093 ! primary neural tube formation GO:0014020 15 14 0,000 0,0878563 0,13068537 ! peptide cross-linking GO:0018149 14 14 0,000 0,0878563 0,13057998 ! vitamin biosynthetic process GO:0009110 14 14 0,000 0,0878563 0,13047475 ! base-excision repair GO:0006284 14 14 0,000 0,0878563 0,1303697 ! response to organic cyclic substance GO:0014070 15 14 0,000 0,0878563 0,13026482 ! leukotriene metabolic process GO:0006691 14 14 0,000 0,0878563 0,1301601 ! regulation of vasoconstriction GO:0019229 14 14 0,000 0,0878563 0,13005556 ! formation of primary germ layer GO:0001704 14 14 0,000 0,0878563 0,12995118 GO:0001707|mesoderm formation, ! DNA modification GO:0006304 14 14 0,000 0,0878563 0,12984697 ! collagen fibril organization GO:0030199 14 14 0,000 0,0878563 0,12974292 ! proteoglycan biosynthetic process GO:0030166 14 14 0,000 0,0878563 0,12963905 ! regulation of blood coagulation GO:0030193 15 14 0,000 0,0878563 0,12953534 ! positive regulation of inflammatory response GO:0050729 14 14 0,000 0,0878563 0,12943179 ! group transfer coenzyme metabolic process GO:0006752 14 14 0,000 0,0878563 0,12932841 ! positive regulation of osteoblast differentiation GO:0045669 14 14 0,000 0,0878563 0,1292252 ! neuromuscular process controlling balance GO:0050885 14 14 0,000 0,0878563 0,12912215 ! aspartate family amino acid metabolic process GO:0009066 14 14 0,000 0,0878563 0,12901926 ! response to molecule of bacterial origin GO:0002237 14 14 0,000 0,0878563 0,12891654 ! negative regulation of protein polymerization GO:0032272 14 14 0,000 0,0878563 0,12881398 ! negative regulation of cell communication GO:0010648 76 76 1,000 0,08795976 0,12886314 ! cell morphogenesis involved in differentiation GO:0000904 82 77 1,000 0,08994119 0,13166134 ! regulation of protein modification process GO:0031399 79 78 1,000 0,09193602 0,13447467 ! positive regulation of protein kinase cascade GO:0010740 79 78 1,000 0,09193602 0,13436802 ! regulation of immune response GO:0050776 78 78 1,000 0,09193602 0,13426155 ! protein import into nucleus, translocation GO:0000060 15 15 0,000 0,09383453 0,1369256 ! positive regulation of fibroblast proliferation GO:0048146 15 15 0,000 0,09383453 0,13681727 ! negative regulation of actin filament depolymerization GO:0030835 15 15 0,000 0,09383453 0,13670912 ! positive regulation of ossification GO:0045778 15 15 0,000 0,09383453 0,13660113 GO:0046852|positive regulation of bone remodeling, GO:0034105|positive regulation of tissue remodeling, ! negative regulation of protein complex assembly GO:0031333 15 15 0,000 0,09383453 0,13649332 ! protein amino acid O-linked glycosylation GO:0006493 15 15 0,000 0,09383453 0,13638567 ! proteoglycan metabolic process GO:0006029 15 15 0,000 0,09383453 0,1362782 ! response to vitamin GO:0033273 15 15 0,000 0,09383453 0,13617089 ! striated muscle cell differentiation GO:0051146 16 15 0,000 0,09383453 0,13606375 ! odontogenesis of dentine-containing tooth GO:0042475 15 15 0,000 0,09383453 0,13595679 ! detection of stimulus involved in sensory perception GO:0050906 16 15 0,000 0,09383453 0,13584999 ! ovarian follicle development GO:0001541 15 15 0,000 0,09383453 0,13574335 ! antigen processing and presentation of peptide antigen GO:0048002 15 15 0,000 0,09383453 0,13563689 ! regulation of smooth muscle contraction GO:0006940 15 15 0,000 0,09383453 0,13553059 ! deoxyribonucleotide metabolic process GO:0009262 15 15 0,000 0,09383453 0,13542446 ! complement activation, classical pathway GO:0006958 15 15 0,000 0,09383453 0,13531849 ! heme metabolic process GO:0042168 15 15 0,000 0,09383453 0,13521269 ! mesoderm morphogenesis GO:0048332 15 15 0,000 0,09383453 0,13510706 ! chromosome condensation GO:0030261 15 15 0,000 0,09383453 0,13500159 ! response to starvation GO:0042594 15 15 0,000 0,09383453 0,13489628 ! response to ionizing radiation GO:0010212 16 15 0,000 0,09383453 0,13479114 ! response to mechanical stimulus GO:0009612 15 15 0,000 0,09383453 0,13468616 ! hydrogen peroxide metabolic process GO:0042743 15 15 0,000 0,09383453 0,13458135 ! regulation of biomineral formation GO:0070167 15 15 0,000 0,09383453 0,1344767 GO:0030500|regulation of bone mineralization, ! regulation of production of molecular mediator of immune response GO:0002700 15 15 0,000 0,09383453 0,13437221 ! cyclic nucleotide biosynthetic process GO:0009190 15 15 0,000 0,09383453 0,13426788 ! cholesterol biosynthetic process GO:0006695 15 15 0,000 0,09383453 0,13416372 ! phospholipid transport GO:0015914 15 15 0,000 0,09383453 0,13405971 ! leukocyte homeostasis GO:0001776 15 15 0,000 0,09383453 0,13395587 ! regulation of cytokine secretion GO:0050707 15 15 0,000 0,09383453 0,13385219 ! glutathione metabolic process GO:0006749 16 15 0,000 0,09383453 0,13374867 ! nicotinamide metabolic process GO:0006769 15 15 0,000 0,09383453 0,13364531 GO:0046496|nicotinamide nucleotide metabolic process, ! positive regulation of B cell activation GO:0050871 15 15 0,000 0,09383453 0,13354211 ! positive regulation of myeloid cell differentiation GO:0045639 16 15 0,000 0,09383453 0,13343907 ! cellular alkene metabolic process GO:0043449 15 15 0,000 0,09383453 0,13333618 ! negative regulation of transcription factor activity GO:0043433 16 15 0,000 0,09383453 0,13323346 GO:0090048|negative regulation of transcription regulator activity, ! somatic diversification of immune receptors GO:0002200 15 15 0,000 0,09383453 0,13313089 ! positive regulation of immune effector process GO:0002699 15 15 0,000 0,09383453 0,13302849 ! neuron projection development GO:0031175 85 80 1,000 0,09596481 0,135944 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 16 16 0,000 0,09977443 0,14123216 ! negative regulation of adenylate cyclase activity GO:0007194 16 16 0,000 0,09977443 0,14112377 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! alkaloid metabolic process GO:0009820 16 16 0,000 0,09977443 0,14101555 ! spliceosomal snRNP biogenesis GO:0000387 16 16 0,000 0,09977443 0,14090749 ! circadian rhythm GO:0007623 16 16 0,000 0,09977443 0,1407996 ! inner ear morphogenesis GO:0042472 16 16 0,000 0,09977443 0,14069187 ! positive regulation of mitosis GO:0045840 16 16 0,000 0,09977443 0,14058431 GO:0051785|positive regulation of nuclear division, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 16 16 0,000 0,09977443 0,14047691 ! vacuole organization GO:0007033 16 16 0,000 0,09977443 0,14036968 ! positive regulation of cytoskeleton organization GO:0051495 16 16 0,000 0,09977443 0,14026261 ! vesicle targeting GO:0006903 17 16 0,000 0,09977443 0,1401557 ! fatty acid beta-oxidation GO:0006635 16 16 0,000 0,09977443 0,14004895 ! triglyceride metabolic process GO:0006641 16 16 0,000 0,09977443 0,13994237 ! iron ion homeostasis GO:0055072 16 16 0,000 0,09977443 0,13983595 ! positive regulation of cell development GO:0010720 16 16 0,000 0,09977443 0,13972969 ! regulation of myeloid leukocyte differentiation GO:0002761 17 16 0,000 0,09977443 0,1396236 ! lymphocyte proliferation GO:0046651 16 16 0,000 0,09977443 0,13951766 ! regulation of systemic arterial blood pressure GO:0003073 17 16 0,000 0,09977443 0,13941188 ! cell fate specification GO:0001708 16 16 0,000 0,09977443 0,13930627 ! pentose metabolic process GO:0019321 16 16 0,000 0,09977443 0,13920081 ! fatty acid transport GO:0015908 16 16 0,000 0,09977443 0,13909552 ! positive regulation of MAPKKK cascade GO:0043410 17 16 0,000 0,09977443 0,13899038 ! cellular response to nutrient levels GO:0031669 16 16 0,000 0,09977443 0,1388854 ! regulation of microtubule cytoskeleton organization GO:0070507 16 16 0,000 0,09977443 0,13878059 ! cofactor catabolic process GO:0051187 16 16 0,000 0,09977443 0,13867592 ! ethanolamine and derivative metabolic process GO:0042439 17 16 0,000 0,09977443 0,13857142 ! polyol metabolic process GO:0019751 16 16 0,000 0,09977443 0,13846708 ! serine family amino acid metabolic process GO:0009069 16 16 0,000 0,09977443 0,13836289 ! glutamine family amino acid catabolic process GO:0009065 17 16 0,000 0,09977443 0,13825885 ! porphyrin metabolic process GO:0006778 16 16 0,000 0,09977443 0,13815498 GO:0033013|tetrapyrrole metabolic process, ! embryonic epithelial tube formation GO:0001838 17 16 0,000 0,09977443 0,13805126 GO:0001841|neural tube formation, ! regulation of JUN kinase activity GO:0043506 17 16 0,000 0,09977443 0,13794769 GO:0043507|positive regulation of JUN kinase activity, ! regulation of cell morphogenesis involved in differentiation GO:0010769 17 16 0,000 0,09977443 0,13784428 ! response to xenobiotic stimulus GO:0009410 16 16 0,000 0,09977443 0,13774103 ! regulation of coagulation GO:0050818 17 16 0,000 0,09977443 0,13763793 ! cellular amino acid derivative metabolic process GO:0006575 87 84 1,000 0,10417215 0,14359706 ! regulation of fibroblast proliferation GO:0048145 17 17 0,000 0,10567626 0,14556154 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 17 17 0,000 0,10567626 0,14545283 ! regulation of actin filament depolymerization GO:0030834 17 17 0,000 0,10567626 0,14534429 ! phosphoinositide biosynthetic process GO:0046489 17 17 0,000 0,10567626 0,1452359 ! regulation of transmembrane transport GO:0034762 17 17 0,000 0,10567626 0,14512768 ! nucleotide-excision repair, DNA damage removal GO:0000718 18 17 0,000 0,10567626 0,14501962 ! leukocyte adhesion GO:0007159 17 17 0,000 0,10567626 0,14491172 ! dicarboxylic acid metabolic process GO:0043648 18 17 0,000 0,10567626 0,14480397 ! sensory perception of smell GO:0007608 17 17 0,000 0,10567626 0,14469639 ! cell junction assembly GO:0034329 18 17 0,000 0,10567626 0,14458897 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 17 17 0,000 0,10567626 0,14448171 ! development of primary male sexual characteristics GO:0046546 17 17 0,000 0,10567626 0,14437461 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 17 17 0,000 0,10567626 0,14426766 ! neural crest cell development GO:0014032 19 17 0,000 0,10567626 0,14416088 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 18 17 0,000 0,10567626 0,14405425 ! negative regulation of cell development GO:0010721 18 17 0,000 0,10567626 0,14394778 GO:0050768|negative regulation of neurogenesis, ! positive regulation of protein secretion GO:0050714 17 17 0,000 0,10567626 0,14384147 ! regulation of osteoblast differentiation GO:0045667 17 17 0,000 0,10567626 0,14373531 ! pyridine nucleotide metabolic process GO:0019362 17 17 0,000 0,10567626 0,14362931 ! pigmentation GO:0043473 17 17 0,000 0,10567626 0,14352347 ! myeloid leukocyte activation GO:0002274 18 17 0,000 0,10567626 0,14341778 ! adult locomotory behavior GO:0008344 17 17 0,000 0,10567626 0,14331225 ! embryonic organ development GO:0048568 17 17 0,000 0,10567626 0,14320687 ! regulation of calcium ion transport GO:0051924 17 17 0,000 0,10567626 0,14310165 ! liver development GO:0001889 17 17 0,000 0,10567626 0,14299658 ! gene silencing GO:0016458 17 17 0,000 0,10567626 0,14289167 ! organophosphate metabolic process GO:0019637 87 86 1,000 0,10834687 0,14639537 GO:0006644|phospholipid metabolic process, ! mRNA export from nucleus GO:0006406 18 18 0,000 0,11154025 0,15059977 ! icosanoid biosynthetic process GO:0046456 18 18 0,000 0,11154025 0,15048952 ! meiosis I GO:0007127 18 18 0,000 0,11154025 0,15037943 ! regulation of metal ion transport GO:0010959 18 18 0,000 0,11154025 0,1502695 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 18 18 0,000 0,11154025 0,15015974 ! mononuclear cell proliferation GO:0032943 18 18 0,000 0,11154025 0,15005013 GO:0070661|leukocyte proliferation, ! response to calcium ion GO:0051592 18 18 0,000 0,11154025 0,14994069 ! negative regulation of response to external stimulus GO:0032102 18 18 0,000 0,11154025 0,1498314 ! cholesterol homeostasis GO:0042632 18 18 0,000 0,11154025 0,14972227 GO:0055092|sterol homeostasis, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 18 18 0,000 0,11154025 0,1496133 ! striated muscle contraction GO:0006941 18 18 0,000 0,11154025 0,1495045 ! neutral lipid metabolic process GO:0006638 18 18 0,000 0,11154025 0,14939584 GO:0006639|acylglycerol metabolic process, ! negative regulation of DNA binding GO:0043392 19 18 0,000 0,11154025 0,14928735 ! ceramide metabolic process GO:0006672 18 18 0,000 0,11154025 0,14917901 GO:0046519|sphingoid metabolic process, ! ribonucleoside monophosphate metabolic process GO:0009161 18 18 0,000 0,11154025 0,14907083 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! telencephalon development GO:0021537 19 18 0,000 0,11154025 0,14896281 ! hexose biosynthetic process GO:0019319 18 18 0,000 0,11154025 0,14885495 ! negative regulation of MAP kinase activity GO:0043407 18 18 0,000 0,11154025 0,14874724 ! B cell differentiation GO:0030183 18 18 0,000 0,11154025 0,14863968 ! cellular response to extracellular stimulus GO:0031668 18 18 0,000 0,11154025 0,14853228 ! BMP signaling pathway GO:0030509 18 18 0,000 0,11154025 0,14842504 ! regulation of microtubule-based process GO:0032886 18 18 0,000 0,11154025 0,14831795 ! establishment of vesicle localization GO:0051650 19 18 0,000 0,11154025 0,14821102 ! brain development GO:0007420 91 90 1,000 0,11682917 0,15512691 ! DNA damage checkpoint GO:0000077 19 19 0,000 0,11736664 0,15572838 ! activation of adenylate cyclase activity GO:0007190 19 19 0,000 0,11736664 0,15561634 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 19 19 0,000 0,11736664 0,15550447 GO:0006956|complement activation, ! negative regulation of DNA metabolic process GO:0051053 19 19 0,000 0,11736664 0,15539276 ! glial cell differentiation GO:0010001 19 19 0,000 0,11736664 0,1552812 ! regulation of pH GO:0006885 19 19 0,000 0,11736664 0,15516981 ! regulation of JAK-STAT cascade GO:0046425 19 19 0,000 0,11736664 0,15505858 ! feeding behavior GO:0007631 19 19 0,000 0,11736664 0,15494751 ! peroxisome organization GO:0007031 19 19 0,000 0,11736664 0,15483659 ! positive regulation of T cell proliferation GO:0042102 19 19 0,000 0,11736664 0,15472584 ! regulation of striated muscle tissue development GO:0016202 20 19 0,000 0,11736664 0,15461524 ! multicellular organismal metabolic process GO:0044236 19 19 0,000 0,11736664 0,1545048 ! metanephros development GO:0001656 19 19 0,000 0,11736664 0,15439452 ! ribonucleoside metabolic process GO:0009119 19 19 0,000 0,11736664 0,15428439 ! regulation of lymphocyte mediated immunity GO:0002706 19 19 0,000 0,11736664 0,15417442 ! positive regulation of T cell differentiation GO:0045582 19 19 0,000 0,11736664 0,15406461 ! nuclear-transcribed mRNA catabolic process GO:0000956 19 19 0,000 0,11736664 0,15395496 ! regulation of protein stability GO:0031647 19 19 0,000 0,11736664 0,15384546 ! hormone biosynthetic process GO:0042446 19 19 0,000 0,11736664 0,15373612 ! biogenic amine biosynthetic process GO:0042401 20 19 0,000 0,11736664 0,15362693 ! eye morphogenesis GO:0048592 19 19 0,000 0,11736664 0,1535179 ! placenta development GO:0001890 19 19 0,000 0,11736664 0,15340902 ! response to heat GO:0009408 19 19 0,000 0,11736664 0,1533003 ! vesicle localization GO:0051648 20 19 0,000 0,11736664 0,15319173 ! negative regulation of cell cycle GO:0045786 92 91 1,000 0,11897611 0,15518257 ! DNA replication GO:0006260 91 91 1,000 0,11897611 0,15507282 ! regulation of muscle development GO:0048634 21 20 0,000 0,12315567 0,16040699 ! negative regulation of cell adhesion GO:0007162 21 20 0,000 0,12315567 0,16029371 ! establishment or maintenance of cell polarity GO:0007163 21 20 0,000 0,12315567 0,16018059 ! negative regulation of binding GO:0051100 21 20 0,000 0,12315567 0,16006762 ! organic ether metabolic process GO:0018904 20 20 0,000 0,12315567 0,15995482 GO:0006662|glycerol ether metabolic process, ! neural tube development GO:0021915 21 20 0,000 0,12315567 0,15984218 ! nucleus organization GO:0006997 20 20 0,000 0,12315567 0,15972969 ! phagocytosis GO:0006909 21 20 0,000 0,12315567 0,15961736 ! positive regulation of gene-specific transcription GO:0043193 20 20 0,000 0,12315567 0,15950519 ! unsaturated fatty acid biosynthetic process GO:0006636 20 20 0,000 0,12315567 0,15939318 ! protein targeting to membrane GO:0006612 22 20 0,000 0,12315567 0,15928133 ! cyclic nucleotide metabolic process GO:0009187 20 20 0,000 0,12315567 0,15916963 ! chromatin remodeling GO:0006338 20 20 0,000 0,12315567 0,15905809 ! detection of abiotic stimulus GO:0009582 21 20 0,000 0,12315567 0,1589467 ! lipid oxidation GO:0034440 20 20 0,000 0,12315567 0,15883547 GO:0019395|fatty acid oxidation, ! female gamete generation GO:0007292 20 20 0,000 0,12315567 0,1587244 ! negative regulation of neuron apoptosis GO:0043524 21 20 0,000 0,12315567 0,15861348 ! monosaccharide biosynthetic process GO:0046364 20 20 0,000 0,12315567 0,15850272 ! RNA modification GO:0009451 20 20 0,000 0,12315567 0,15839211 ! regulation of B cell activation GO:0050864 20 20 0,000 0,12315567 0,15828165 ! tissue morphogenesis GO:0048729 94 93 1,000 0,12330009 0,15835684 ! epidermis development GO:0008544 94 94 1,000 0,1254767 0,16104008 ! mitotic sister chromatid segregation GO:0000070 21 21 0,000 0,12890756 0,16532821 ! mRNA catabolic process GO:0006402 21 21 0,000 0,12890756 0,16521324 ! positive regulation of adenylate cyclase activity GO:0045762 21 21 0,000 0,12890756 0,16509842 GO:0051349|positive regulation of lyase activity, GO:0031281|positive regulation of cyclase activity, ! protein amino acid lipidation GO:0006497 21 21 0,000 0,12890756 0,16498377 ! receptor-mediated endocytosis GO:0006898 21 21 0,000 0,12890756 0,16486928 ! Notch signaling pathway GO:0007219 22 21 0,000 0,12890756 0,16475495 ! morphogenesis of embryonic epithelium GO:0016331 22 21 0,000 0,12890756 0,16464077 ! ear morphogenesis GO:0042471 21 21 0,000 0,12890756 0,16452675 ! organic anion transport GO:0015711 21 21 0,000 0,12890756 0,16441289 ! cholesterol transport GO:0030301 21 21 0,000 0,12890756 0,16429919 GO:0015918|sterol transport, ! spliceosome assembly GO:0000245 22 21 0,000 0,12890756 0,16418565 ! regulation of Rab protein signal transduction GO:0032483 21 21 0,000 0,12890756 0,16407226 GO:0032313|regulation of Rab GTPase activity, ! DNA integrity checkpoint GO:0031570 21 21 0,000 0,12890756 0,16395903 ! regulation of leukocyte mediated immunity GO:0002703 21 21 0,000 0,12890756 0,16384595 ! regulation of multicellular organism growth GO:0040014 21 21 0,000 0,12890756 0,16373303 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 21 21 0,000 0,12890756 0,16362027 ! regulation of proteolysis GO:0030162 21 21 0,000 0,12890756 0,16350766 ! negative regulation of hydrolase activity GO:0051346 21 21 0,000 0,12890756 0,16339521 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 21 21 0,000 0,12890756 0,16328291 ! negative regulation of protein transport GO:0051224 21 21 0,000 0,12890756 0,16317076 ! regulation of system process GO:0044057 98 98 1,000 0,13427569 0,16984907 ! RNA export from nucleus GO:0006405 22 22 0,000 0,13462256 0,17017104 ! sister chromatid segregation GO:0000819 22 22 0,000 0,13462256 0,1700544 ! cellular amide metabolic process GO:0043603 22 22 0,000 0,13462256 0,16993792 ! regulation of ion transport GO:0043269 22 22 0,000 0,13462256 0,16982161 ! odontogenesis GO:0042476 22 22 0,000 0,13462256 0,16970545 ! cell junction organization GO:0034330 23 22 0,000 0,13462256 0,16958945 ! positive regulation of lymphocyte proliferation GO:0050671 22 22 0,000 0,13462256 0,16947361 GO:0032946|positive regulation of mononuclear cell proliferation, GO:0070665|positive regulation of leukocyte proliferation, GO:0070668|positive regulation of mast cell proliferation, ! hormone-mediated signaling GO:0009755 22 22 0,000 0,13462256 0,16935793 ! maintenance of protein location in cell GO:0032507 23 22 0,000 0,13462256 0,16924241 ! ovulation cycle process GO:0022602 22 22 0,000 0,13462256 0,16912704 ! spindle organization GO:0007051 22 22 0,000 0,13462256 0,16901183 ! pigment biosynthetic process GO:0046148 22 22 0,000 0,13462256 0,16889678 ! cell chemotaxis GO:0060326 23 22 0,000 0,13462256 0,16878188 GO:0030595|leukocyte chemotaxis, ! respiratory gaseous exchange GO:0007585 22 22 0,000 0,13462256 0,16866715 ! erythrocyte differentiation GO:0030218 23 22 0,000 0,13462256 0,16855256 ! male sex differentiation GO:0046661 22 22 0,000 0,13462256 0,16843813 ! sterol biosynthetic process GO:0016126 22 22 0,000 0,13462256 0,16832386 ! biopolymer methylation GO:0043414 22 22 0,000 0,13462256 0,16820974 GO:0032259|methylation, ! regulation of adaptive immune response GO:0002819 22 22 0,000 0,13462256 0,16809578 ! detection of external stimulus GO:0009581 23 22 0,000 0,13462256 0,16798197 ! neuron migration GO:0001764 22 22 0,000 0,13462256 0,16786832 ! regulation of Wnt receptor signaling pathway GO:0030111 23 22 0,000 0,13462256 0,16775481 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 22 22 0,000 0,13462256 0,16764147 ! positive regulation of lymphocyte differentiation GO:0045621 22 22 0,000 0,13462256 0,16752827 ! fatty acid catabolic process GO:0009062 23 22 0,000 0,13462256 0,16741523 ! aerobic respiration GO:0009060 22 22 0,000 0,13462256 0,16730234 ! cytokine production GO:0001816 22 22 0,000 0,13462256 0,1671896 ! cytokinesis GO:0000910 23 22 0,000 0,13462256 0,16707702 ! pyrimidine nucleotide metabolic process GO:0006220 22 22 0,000 0,13462256 0,16696458 ! anti-apoptosis GO:0006916 100 99 1,000 0,13649755 0,16917618 ! ectoderm development GO:0007398 99 99 1,000 0,13649755 0,16906249 ! response to other organism GO:0051707 101 100 1,000 0,13872784 0,17170948 ! response to hydrogen peroxide GO:0042542 24 23 0,000 0,14030089 0,17353995 ! epithelial cell differentiation GO:0030855 23 23 0,000 0,14030089 0,17342356 ! viral infectious cycle GO:0019058 23 23 0,000 0,14030089 0,17330733 ! regulation of hormone secretion GO:0046883 23 23 0,000 0,14030089 0,17319125 ! response to estrogen stimulus GO:0043627 23 23 0,000 0,14030089 0,17307532 ! negative regulation of protein complex disassembly GO:0043242 23 23 0,000 0,14030089 0,17295955 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 23 23 0,000 0,14030089 0,17284394 ! mitotic cell cycle checkpoint GO:0007093 24 23 0,000 0,14030089 0,17272848 ! induction of apoptosis by extracellular signals GO:0008624 23 23 0,000 0,14030089 0,17261317 ! regulation of ARF protein signal transduction GO:0032012 23 23 0,000 0,14030089 0,17249802 ! endocrine system development GO:0035270 23 23 0,000 0,14030089 0,17238302 ! lipoprotein biosynthetic process GO:0042158 23 23 0,000 0,14030089 0,17226818 ! female gonad development GO:0008585 23 23 0,000 0,14030089 0,17215348 ! monovalent inorganic cation homeostasis GO:0055067 23 23 0,000 0,14030089 0,17203894 ! lipid homeostasis GO:0055088 23 23 0,000 0,14030089 0,17192456 ! Rho protein signal transduction GO:0007266 24 23 0,000 0,14030089 0,17181032 ! regulation of JNK cascade GO:0046328 25 23 0,000 0,14030089 0,17169624 ! mitochondrial transport GO:0006839 24 24 0,000 0,14594278 0,17848211 ! gliogenesis GO:0042063 24 24 0,000 0,14594278 0,17836375 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 26 24 0,000 0,14594278 0,17824555 ! cellular amino acid biosynthetic process GO:0008652 24 24 0,000 0,14594278 0,17812751 ! heterocycle biosynthetic process GO:0018130 24 24 0,000 0,14594278 0,17800962 ! T cell differentiation GO:0030217 24 24 0,000 0,14594278 0,17789189 ! nucleotide catabolic process GO:0009166 24 24 0,000 0,14594278 0,17777432 ! erythrocyte homeostasis GO:0034101 25 24 0,000 0,14594278 0,1776569 ! ovulation cycle GO:0042698 24 24 0,000 0,14594278 0,17753963 ! maintenance of protein location GO:0045185 25 24 0,000 0,14594278 0,17742252 ! oxidoreduction coenzyme metabolic process GO:0006733 24 24 0,000 0,14594278 0,17730556 ! androgen receptor signaling pathway GO:0030521 24 24 0,000 0,14594278 0,17718876 ! epithelial tube morphogenesis GO:0060562 25 24 0,000 0,14594278 0,17707211 ! regulation of actin filament polymerization GO:0030833 25 25 0,000 0,15154846 0,18375251 ! negative regulation of secretion GO:0051048 26 25 0,000 0,15154846 0,1836317 ! protein amino acid N-linked glycosylation GO:0006487 25 25 0,000 0,15154846 0,18351105 ! sensory perception of chemical stimulus GO:0007606 25 25 0,000 0,15154846 0,18339056 ! cellular component disassembly GO:0022411 26 25 0,000 0,15154846 0,18327022 ! endosome transport GO:0016197 25 25 0,000 0,15154846 0,18315004 ! alcohol biosynthetic process GO:0046165 25 25 0,000 0,15154846 0,18303002 ! development of primary female sexual characteristics GO:0046545 25 25 0,000 0,15154846 0,18291016 GO:0046660|female sex differentiation, ! excretion GO:0007588 25 25 0,000 0,15154846 0,18279046 ! generation of a signal involved in cell-cell signaling GO:0003001 27 25 0,000 0,15154846 0,18267091 ! gastrulation GO:0007369 25 25 0,000 0,15154846 0,18255151 ! icosanoid metabolic process GO:0006690 25 25 0,000 0,15154846 0,18243228 ! regulation of endocytosis GO:0030100 25 25 0,000 0,15154846 0,1823132 ! JAK-STAT cascade GO:0007259 26 25 0,000 0,15154846 0,18219427 ! positive regulation of cytokine production GO:0001819 25 25 0,000 0,15154846 0,1820755 ! positive regulation of defense response GO:0031349 26 26 0,000 0,15711817 0,18864416 ! glycolysis GO:0006096 26 26 0,000 0,15711817 0,18852134 ! transforming growth factor beta receptor signaling pathway GO:0007179 26 26 0,000 0,15711817 0,18839869 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 26 26 0,000 0,15711817 0,18827619 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 26 26 0,000 0,15711817 0,18815385 ! induction of apoptosis by intracellular signals GO:0008629 26 26 0,000 0,15711817 0,18803168 ! cellular defense response GO:0006968 26 26 0,000 0,15711817 0,18790966 ! positive regulation of cytokine biosynthetic process GO:0042108 26 26 0,000 0,15711817 0,1877878 ! double-strand break repair GO:0006302 27 26 0,000 0,15711817 0,18766609 ! regulation of protein secretion GO:0050708 26 26 0,000 0,15711817 0,18754455 ! germ cell development GO:0007281 27 26 0,000 0,15711817 0,18742316 ! regulation of blood vessel size GO:0050880 27 26 0,000 0,15711817 0,18730193 GO:0035150|regulation of tube size, ! pigment metabolic process GO:0042440 26 26 0,000 0,15711817 0,18718085 ! maintenance of location in cell GO:0051651 27 26 0,000 0,15711817 0,18705994 ! chloride transport GO:0006821 27 27 0,000 0,16265212 0,19352347 ! regulation of neurotransmitter levels GO:0001505 31 27 0,000 0,16265212 0,19339861 ! monocarboxylic acid transport GO:0015718 27 27 0,000 0,16265212 0,19327392 ! cAMP-mediated signaling GO:0019933 27 27 0,000 0,16265212 0,19314939 ! peptide metabolic process GO:0006518 29 27 0,000 0,16265212 0,19302502 ! activation of caspase activity GO:0006919 27 27 0,000 0,16265212 0,1929008 ! mesenchymal cell development GO:0014031 29 27 0,000 0,16265212 0,19277675 GO:0060485|mesenchyme development, GO:0048762|mesenchymal cell differentiation, ! inner ear development GO:0048839 27 27 0,000 0,16265212 0,19265286 ! defense response to bacterium GO:0042742 27 27 0,000 0,16265212 0,19252913 ! isoprenoid metabolic process GO:0006720 27 27 0,000 0,16265212 0,19240555 ! glutamine family amino acid metabolic process GO:0009064 28 27 0,000 0,16265212 0,19228214 ! cell growth GO:0016049 27 27 0,000 0,16265212 0,19215888 ! tRNA aminoacylation for protein translation GO:0006418 28 28 0,000 0,16815053 0,1985275 GO:0043038|amino acid activation, GO:0043039|tRNA aminoacylation, ! stress-activated protein kinase signaling pathway GO:0031098 28 28 0,000 0,16815053 0,1984004 GO:0007254|JNK cascade, ! regulation of muscle contraction GO:0006937 28 28 0,000 0,16815053 0,19827347 ! unsaturated fatty acid metabolic process GO:0033559 28 28 0,000 0,16815053 0,1981467 ! sulfur compound biosynthetic process GO:0044272 28 28 0,000 0,16815053 0,19802008 ! keratinocyte differentiation GO:0030216 28 28 0,000 0,16815053 0,19789363 ! developmental growth GO:0048589 28 28 0,000 0,16815053 0,19776735 ! glycerophospholipid biosynthetic process GO:0046474 30 29 0,000 0,17361364 0,20406246 ! leukocyte migration GO:0050900 30 29 0,000 0,17361364 0,2039324 ! branching morphogenesis of a tube GO:0048754 29 29 0,000 0,17361364 0,20380251 ! antigen processing and presentation GO:0019882 29 29 0,000 0,17361364 0,20367278 ! DNA-dependent DNA replication GO:0006261 29 29 0,000 0,17361364 0,20354322 ! tRNA processing GO:0008033 29 29 0,000 0,17361364 0,20341382 ! adult behavior GO:0030534 30 29 0,000 0,17361364 0,20328459 ! regulation of protein polymerization GO:0032271 29 29 0,000 0,17361364 0,20315552 ! transition metal ion transport GO:0000041 31 30 0,000 0,17904167 0,20937423 ! RNA catabolic process GO:0006401 30 30 0,000 0,17904167 0,20924146 ! ER to Golgi vesicle-mediated transport GO:0006888 30 30 0,000 0,17904167 0,20910887 ! positive regulation of peptidase activity GO:0010952 30 30 0,000 0,17904167 0,20897643 GO:0043280|positive regulation of caspase activity, ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 30 30 0,000 0,17904167 0,20884417 ! neuropeptide signaling pathway GO:0007218 30 30 0,000 0,17904167 0,20871207 ! regulation of protein complex disassembly GO:0043244 30 30 0,000 0,17904167 0,20858015 ! positive regulation of protein amino acid phosphorylation GO:0001934 30 30 0,000 0,17904167 0,20844838 ! response to temperature stimulus GO:0009266 30 30 0,000 0,17904167 0,20831679 ! regulation of ossification GO:0030278 30 30 0,000 0,17904167 0,20818536 ! immunoglobulin mediated immune response GO:0016064 30 30 0,000 0,17904167 0,20805409 GO:0019724|B cell mediated immunity, ! regulation of inflammatory response GO:0050727 30 30 0,000 0,17904167 0,20792299 ! water-soluble vitamin metabolic process GO:0006767 30 30 0,000 0,17904167 0,20779206 ! vesicle organization GO:0016050 30 30 0,000 0,17904167 0,20766129 ! cellular amino acid derivative biosynthetic process GO:0042398 31 30 0,000 0,17904167 0,20753069 ! establishment of organelle localization GO:0051656 31 30 0,000 0,17904167 0,20740024 ! regulation of translational initiation GO:0006446 31 31 0,000 0,18443482 0,21351343 ! membrane fusion GO:0006944 31 31 0,000 0,18443482 0,2133794 ! B cell activation GO:0042113 31 31 0,000 0,18443482 0,21324553 ! negative regulation of cytoskeleton organization GO:0051494 32 31 0,000 0,18443482 0,21311184 ! lipoprotein metabolic process GO:0042157 31 31 0,000 0,18443482 0,21297831 ! ion transmembrane transport GO:0034220 31 31 0,000 0,18443482 0,21284495 GO:0015985|energy coupled proton transport, down electrochemical gradient, GO:0015986|ATP synthesis coupled proton transport, ! aging GO:0007568 32 31 0,000 0,18443482 0,21271175 ! glycerolipid biosynthetic process GO:0045017 32 31 0,000 0,18443482 0,21257872 ! digestion GO:0007586 31 31 0,000 0,18443482 0,21244586 ! nucleoside metabolic process GO:0009116 31 31 0,000 0,18443482 0,21231317 ! regulation of heart contraction GO:0008016 31 31 0,000 0,18443482 0,21218064 ! sphingolipid metabolic process GO:0006665 31 31 0,000 0,18443482 0,21204827 ! camera-type eye development GO:0043010 31 31 0,000 0,18443482 0,21191607 ! extracellular matrix organization GO:0030198 31 31 0,000 0,18443482 0,21178404 ! ribonucleoprotein complex assembly GO:0022618 32 31 0,000 0,18443482 0,21165217 ! epidermal cell differentiation GO:0009913 31 31 0,000 0,18443482 0,21152046 ! regulation of myeloid cell differentiation GO:0045637 32 31 0,000 0,18443482 0,21138892 ! negative regulation of cell growth GO:0030308 32 32 0,000 0,18979333 0,21739535 ! cell redox homeostasis GO:0045454 32 32 0,000 0,18979333 0,21726032 ! glucose catabolic process GO:0006007 32 32 0,000 0,18979333 0,21712546 ! lipid modification GO:0030258 32 32 0,000 0,18979333 0,21699076 ! glycosaminoglycan metabolic process GO:0030203 34 32 0,000 0,18979333 0,21685624 ! regulation of vesicle-mediated transport GO:0060627 33 32 0,000 0,18979333 0,21672188 ! cell maturation GO:0048469 32 32 0,000 0,18979333 0,21658768 ! morphogenesis of a branching structure GO:0001763 32 32 0,000 0,18979333 0,21645366 ! nuclear export GO:0051168 32 32 0,000 0,18979333 0,2163198 ! kidney development GO:0001822 32 32 0,000 0,18979333 0,2161861 ! protein maturation by peptide bond cleavage GO:0051605 32 32 0,000 0,18979333 0,21605257 ! maintenance of location GO:0051235 33 32 0,000 0,18979333 0,2159192 ! negative regulation of cell size GO:0045792 33 33 0,000 0,19511741 0,22183923 ! regulation of cellular response to stress GO:0080135 35 33 0,000 0,19511741 0,22170246 ! regulation of protein complex assembly GO:0043254 33 33 0,000 0,19511741 0,22156586 ! membrane lipid metabolic process GO:0006643 33 33 0,000 0,19511741 0,22142943 ! regulation of actin polymerization or depolymerization GO:0008064 33 33 0,000 0,19511741 0,22129316 ! regulation of neuron differentiation GO:0045664 34 33 0,000 0,19511741 0,22115707 ! regulation of neuron apoptosis GO:0043523 34 33 0,000 0,19511741 0,22102114 ! regulation of actin filament length GO:0030832 34 34 0,000 0,20040728 0,22687384 ! response to metal ion GO:0010038 34 34 0,000 0,20040728 0,22673457 ! ear development GO:0043583 34 34 0,000 0,20040728 0,22659547 ! muscle cell differentiation GO:0042692 35 34 0,000 0,20040728 0,22645654 ! coenzyme biosynthetic process GO:0009108 34 34 0,000 0,20040728 0,22631778 ! nucleoside monophosphate biosynthetic process GO:0009124 34 34 0,000 0,20040728 0,22617919 ! secondary metabolic process GO:0019748 34 34 0,000 0,20040728 0,22604077 ! negative regulation of response to stimulus GO:0048585 34 34 0,000 0,20040728 0,22590252 ! detection of stimulus GO:0051606 36 34 0,000 0,20040728 0,22576443 ! acute inflammatory response GO:0002526 35 35 0,000 0,20566315 0,23154379 ! regulation of cellular component size GO:0032535 35 35 0,000 0,20566315 0,23140243 ! regulation of cytokine biosynthetic process GO:0042035 35 35 0,000 0,20566315 0,23126124 ! mesoderm development GO:0007498 35 35 0,000 0,20566315 0,23112023 ! multicellular organism reproduction GO:0032504 36 35 0,000 0,20566315 0,23097939 GO:0048609|reproductive process in a multicellular organism, ! inorganic anion transport GO:0015698 35 35 0,000 0,20566315 0,23083872 ! response to steroid hormone stimulus GO:0048545 35 35 0,000 0,20566315 0,23069822 ! regulation of immune effector process GO:0002697 35 35 0,000 0,20566315 0,2305579 ! hydrogen transport GO:0006818 36 36 0,000 0,21088523 0,23626838 GO:0015992|proton transport, ! response to inorganic substance GO:0010035 36 36 0,000 0,21088523 0,23612484 ! aminoglycan metabolic process GO:0006022 38 36 0,000 0,21088523 0,23598147 ! oxygen and reactive oxygen species metabolic process GO:0006800 37 36 0,000 0,21088523 0,23583828 ! regulation of mitosis GO:0007088 37 36 0,000 0,21088523 0,23569526 GO:0051783|regulation of nuclear division, ! embryonic limb morphogenesis GO:0030326 36 36 0,000 0,21088523 0,23555241 GO:0035113|embryonic appendage morphogenesis, ! female pregnancy GO:0007565 37 36 0,000 0,21088523 0,23540974 ! RNA elongation from RNA polymerase II promoter GO:0006368 36 36 0,000 0,21088523 0,23526724 ! positive regulation of organelle organization GO:0010638 36 36 0,000 0,21088523 0,23512491 ! heterocycle catabolic process GO:0046700 36 36 0,000 0,21088523 0,23498276 ! gonad development GO:0008406 36 36 0,000 0,21088523 0,23484077 ! coagulation GO:0050817 39 36 0,000 0,21088523 0,23469896 GO:0007596|blood coagulation, ! regulation of adenylate cyclase activity GO:0045761 37 37 0,000 0,21607374 0,24032825 GO:0031279|regulation of cyclase activity, GO:0051339|regulation of lyase activity, ! meiosis GO:0007126 37 37 0,000 0,21607374 0,24018329 GO:0051327|M phase of meiotic cell cycle, ! lymphocyte mediated immunity GO:0002449 37 37 0,000 0,21607374 0,24003852 ! eye development GO:0001654 37 37 0,000 0,21607374 0,23989392 ! negative regulation of growth GO:0045926 37 37 0,000 0,21607374 0,23974949 ! DNA damage response, signal transduction GO:0042770 37 37 0,000 0,21607374 0,23960524 ! ATP synthesis coupled electron transport GO:0042773 37 37 0,000 0,21607374 0,23946116 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! cellular amino acid catabolic process GO:0009063 38 37 0,000 0,21607374 0,23931725 ! regulation of Rho protein signal transduction GO:0035023 37 37 0,000 0,21607374 0,23917352 ! positive regulation of secretion GO:0051047 39 38 0,000 0,22122889 0,2447328 ! neurotransmitter transport GO:0006836 40 38 0,000 0,22122889 0,24458599 ! cellular hormone metabolic process GO:0034754 39 38 0,000 0,22122889 0,24443935 ! chromosome segregation GO:0007059 38 38 0,000 0,22122889 0,2442929 ! urogenital system development GO:0001655 38 38 0,000 0,22122889 0,24414661 ! hexose catabolic process GO:0019320 38 38 0,000 0,22122889 0,2440005 ! RNA elongation GO:0006354 38 38 0,000 0,22122889 0,24385457 ! meiotic cell cycle GO:0051321 38 38 0,000 0,22122889 0,24370881 ! steroid hormone receptor signaling pathway GO:0030518 38 38 0,000 0,22122889 0,24356323 ! regulation of cAMP biosynthetic process GO:0030817 39 39 0,000 0,22635089 0,24905354 ! hemostasis GO:0007599 42 39 0,000 0,22635089 0,24890494 ! positive regulation of protein modification process GO:0031401 39 39 0,000 0,22635089 0,24875652 ! response to unfolded protein GO:0006986 39 39 0,000 0,22635089 0,24860827 ! nucleoside monophosphate metabolic process GO:0009123 39 39 0,000 0,22635089 0,2484602 ! fatty acid biosynthetic process GO:0006633 39 39 0,000 0,22635089 0,24831231 ! nucleotide-excision repair GO:0006289 40 39 0,000 0,22635089 0,24816459 ! intracellular protein transmembrane transport GO:0065002 39 39 0,000 0,22635089 0,24801705 ! regulation of MAPKKK cascade GO:0043408 41 39 0,000 0,22635089 0,24786969 ! positive regulation of T cell activation GO:0050870 39 39 0,000 0,22635089 0,24772249 ! developmental maturation GO:0021700 39 39 0,000 0,22635089 0,24757548 ! lymphocyte differentiation GO:0030098 39 39 0,000 0,22635089 0,24742864 ! limb development GO:0060173 39 39 0,000 0,22635089 0,24728197 GO:0048736|appendage development, GO:0035107|appendage morphogenesis, ! regulation of cAMP metabolic process GO:0030814 40 40 0,000 0,23143994 0,25269183 ! DNA catabolic process GO:0006308 41 40 0,000 0,23143994 0,25254222 ! intracellular receptor-mediated signaling pathway GO:0030522 40 40 0,000 0,23143994 0,25239278 ! myeloid cell differentiation GO:0030099 42 40 0,000 0,23143994 0,25224353 ! organelle localization GO:0051640 41 40 0,000 0,23143994 0,25209445 ! regulation of nucleotide biosynthetic process GO:0030808 41 41 0,000 0,23649625 0,25744985 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! cell cycle checkpoint GO:0000075 42 41 0,000 0,23649625 0,25729787 ! amine catabolic process GO:0009310 42 41 0,000 0,23649625 0,25714607 ! elevation of cytosolic calcium ion concentration GO:0007204 41 41 0,000 0,23649625 0,25699446 ! phospholipid biosynthetic process GO:0008654 42 41 0,000 0,23649625 0,25684302 ! leukocyte mediated immunity GO:0002443 41 41 0,000 0,23649625 0,25669175 ! regulation of Ras GTPase activity GO:0032318 41 41 0,000 0,23649625 0,25654067 ! monosaccharide catabolic process GO:0046365 41 41 0,000 0,23649625 0,25638976 ! respiratory electron transport chain GO:0022904 43 42 0,000 0,24152004 0,26168221 ! regulation of cyclic nucleotide metabolic process GO:0030799 42 42 0,000 0,24152004 0,26152846 ! cytosolic calcium ion homeostasis GO:0051480 42 42 0,000 0,24152004 0,26137489 ! development of primary sexual characteristics GO:0045137 42 42 0,000 0,24152004 0,2612215 ! protein ubiquitination GO:0016567 43 42 0,000 0,24152004 0,26106829 ! response to protein stimulus GO:0051789 42 42 0,000 0,24152004 0,26091526 ! forebrain development GO:0030900 43 42 0,000 0,24152004 0,26076241 ! one-carbon metabolic process GO:0006730 42 42 0,000 0,24152004 0,26060974 ! reproductive structure development GO:0048608 43 43 0,000 0,2465115 0,26584008 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 43 43 0,000 0,2465115 0,26568462 ! mitochondrion organization GO:0007005 44 43 0,000 0,2465115 0,26552934 ! alcohol catabolic process GO:0046164 43 43 0,000 0,2465115 0,26537424 ! homeostasis of number of cells GO:0048872 44 43 0,000 0,2465115 0,26521932 ! regulation of nucleotide metabolic process GO:0006140 43 43 0,000 0,2465115 0,26506458 ! humoral immune response GO:0006959 44 44 0,000 0,25147084 0,2702395 ! mRNA transport GO:0051028 44 44 0,000 0,25147084 0,27008202 ! protein import into nucleus GO:0006606 44 44 0,000 0,25147084 0,26992472 ! negative regulation of organelle organization GO:0010639 45 44 0,000 0,25147084 0,26976761 ! vitamin metabolic process GO:0006766 44 44 0,000 0,25147084 0,26961067 ! positive regulation of lymphocyte activation GO:0051251 44 44 0,000 0,25147084 0,26945392 ! amine biosynthetic process GO:0009309 46 45 0,000 0,25639825 0,27457407 ! regulation of actin cytoskeleton organization GO:0032956 46 45 0,000 0,25639825 0,27441462 ! steroid biosynthetic process GO:0006694 46 45 0,000 0,25639825 0,27425535 ! nuclear import GO:0051170 45 45 0,000 0,25639825 0,27409627 ! protein processing GO:0016485 45 45 0,000 0,25639825 0,27393738 ! regulation of actin filament-based process GO:0032970 47 46 0,000 0,26129395 0,27900622 ! cyclic-nucleotide-mediated signaling GO:0019935 46 46 0,000 0,26129395 0,27884467 ! tube morphogenesis GO:0035239 47 46 0,000 0,26129395 0,2786833 ! transcription initiation from RNA polymerase II promoter GO:0006367 46 46 0,000 0,26129395 0,27852212 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 47 47 0,000 0,26615812 0,28354302 ! regulation of blood pressure GO:0008217 48 47 0,000 0,26615812 0,28337921 ! sex differentiation GO:0007548 47 47 0,000 0,26615812 0,2832156 ! rhythmic process GO:0048511 47 47 0,000 0,26615812 0,28305217 ! regulation of cell cycle process GO:0010564 50 48 0,000 0,27099097 0,28802559 ! protein localization in nucleus GO:0034504 48 48 0,000 0,27099097 0,28785958 ! DNA recombination GO:0006310 48 48 0,000 0,27099097 0,28769376 ! leukocyte differentiation GO:0002521 50 49 0,000 0,2757927 0,29262288 ! cell cycle arrest GO:0007050 49 49 0,000 0,2757927 0,29245452 ! cellular lipid catabolic process GO:0044242 50 49 0,000 0,2757927 0,29228634 ! response to nutrient GO:0007584 49 49 0,000 0,2757927 0,29211836 ! response to bacterium GO:0009617 50 49 0,000 0,2757927 0,29195057 ! cofactor biosynthetic process GO:0051188 49 49 0,000 0,2757927 0,29178298 ! positive regulation of cell activation GO:0050867 49 49 0,000 0,2757927 0,29161558 GO:0002696|positive regulation of leukocyte activation, ! regulation of defense response GO:0031347 50 50 0,000 0,2805635 0,29648998 ! negative regulation of transport GO:0051051 51 50 0,000 0,2805635 0,29632008 ! chromatin assembly GO:0031497 50 50 0,000 0,2805635 0,29615036 GO:0006334|nucleosome assembly, ! RNA transport GO:0050658 50 50 0,000 0,2805635 0,29598084 GO:0050657|nucleic acid transport, GO:0051236|establishment of RNA localization, ! T cell activation GO:0042110 51 50 0,000 0,2805635 0,29581152 ! nitrogen compound catabolic process GO:0044270 51 50 0,000 0,2805635 0,29564239 ! regulation of neurogenesis GO:0050767 51 50 0,000 0,2805635 0,29547345 ! transcription initiation GO:0006352 50 50 0,000 0,2805635 0,2953047 ! anatomical structure homeostasis GO:0060249 51 50 0,000 0,2805635 0,29513615 ! protein modification by small protein conjugation GO:0032446 52 51 0,000 0,28530357 0,29995121 ! rRNA metabolic process GO:0016072 51 51 0,000 0,28530357 0,2997802 GO:0006364|rRNA processing, ! protein-DNA complex assembly GO:0065004 51 51 0,000 0,28530357 0,29960939 ! ATP biosynthetic process GO:0006754 51 51 0,000 0,28530357 0,29943877 ! protein maturation GO:0051604 51 51 0,000 0,28530357 0,29926834 ! RNA localization GO:0006403 52 52 0,000 0,29001309 0,30403534 ! cholesterol metabolic process GO:0008203 52 52 0,000 0,29001309 0,30386249 ! cell fate commitment GO:0045165 52 52 0,000 0,29001309 0,30368984 ! regulation of GTPase activity GO:0043087 53 52 0,000 0,29001309 0,30351739 ! regulation of body fluid levels GO:0050878 55 52 0,000 0,29001309 0,30334513 ! tRNA metabolic process GO:0006399 53 53 0,000 0,29469227 0,30806458 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 53 53 0,000 0,29469227 0,30788994 ! carbohydrate catabolic process GO:0016052 53 53 0,000 0,29469227 0,30771549 ! hormone metabolic process GO:0042445 55 54 0,000 0,29934128 0,31239297 ! sulfur metabolic process GO:0006790 55 54 0,000 0,29934128 0,31221618 ! nucleosome organization GO:0034728 55 55 0,000 0,30396034 0,31685458 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 55 55 0,000 0,30396034 0,31667547 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! in utero embryonic development GO:0001701 55 55 0,000 0,30396034 0,31649655 ! protein modification by small protein conjugation or removal GO:0070647 56 55 0,000 0,30396034 0,31631784 ! ribonucleoside triphosphate biosynthetic process GO:0009201 56 56 0,000 0,30854961 0,32091249 ! regulation of nervous system development GO:0051960 57 56 0,000 0,30854961 0,32073149 ! ATP metabolic process GO:0046034 57 57 0,000 0,31310929 0,32528772 ! nucleoside triphosphate biosynthetic process GO:0009142 57 57 0,000 0,31310929 0,32510446 ! regulation of cell development GO:0060284 60 59 0,000 0,32214062 0,33429345 ! sterol metabolic process GO:0016125 59 59 0,000 0,32214062 0,33410533 ! protein localization in organelle GO:0033365 59 59 0,000 0,32214062 0,33391742 ! immune effector process GO:0002252 59 59 0,000 0,32214062 0,33372972 ! potassium ion transport GO:0006813 60 60 0,000 0,32661265 0,33817253 ! cellular respiration GO:0045333 62 61 0,000 0,33105582 0,3425805 ! carboxylic acid catabolic process GO:0046395 63 61 0,000 0,33105582 0,34238826 GO:0016054|organic acid catabolic process, ! positive regulation of cellular protein metabolic process GO:0032270 61 61 0,000 0,33105582 0,34219623 ! lipid transport GO:0006869 62 62 0,000 0,33547032 0,34656491 ! purine ribonucleoside triphosphate metabolic process GO:0009205 62 62 0,000 0,33547032 0,34637076 ! protein import GO:0017038 62 62 0,000 0,33547032 0,34617682 ! regulation of secretion GO:0051046 65 63 0,000 0,33985633 0,35050656 ! negative regulation of cellular component organization GO:0051129 65 63 0,000 0,33985633 0,35031053 ! glucose metabolic process GO:0006006 63 63 0,000 0,33985633 0,35011471 ! ribonucleoside triphosphate metabolic process GO:0009199 63 63 0,000 0,33985633 0,34991912 ! purine nucleoside triphosphate metabolic process GO:0009144 63 63 0,000 0,33985633 0,34972374 ! regulation of cytoskeleton organization GO:0051493 66 64 0,000 0,34421404 0,35401031 ! positive regulation of protein metabolic process GO:0051247 64 64 0,000 0,34421404 0,35381287 ! regulation of hormone levels GO:0010817 66 65 0,000 0,34854361 0,35806348 ! protein amino acid glycosylation GO:0006486 66 66 0,000 0,35284523 0,36228065 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! nucleoside triphosphate metabolic process GO:0009141 66 66 0,000 0,35284523 0,36207893 ! DNA packaging GO:0006323 66 66 0,000 0,35284523 0,36187744 ! muscle contraction GO:0006936 67 67 0,000 0,35711907 0,36605698 ! negative regulation of cell differentiation GO:0045596 68 67 0,000 0,35711907 0,3658535 ! purine ribonucleotide biosynthetic process GO:0009152 68 68 0,000 0,36136531 0,36999793 ! chromatin assembly or disassembly GO:0006333 68 68 0,000 0,36136531 0,36979249 ! regulation of cell size GO:0008361 68 68 0,000 0,36136531 0,36958728 ! response to nutrient levels GO:0031667 69 69 0,000 0,36558413 0,3736947 ! regulation of mitotic cell cycle GO:0007346 72 69 0,000 0,36558413 0,37348755 ! growth GO:0040007 70 70 0,000 0,36977569 0,37756044 ! carboxylic acid biosynthetic process GO:0046394 70 70 0,000 0,36977569 0,37735138 GO:0016053|organic acid biosynthetic process, ! translational elongation GO:0006414 71 71 0,000 0,37394017 0,38139 ! oxidative phosphorylation GO:0006119 71 71 0,000 0,37394017 0,38117905 ! calcium ion homeostasis GO:0055074 71 71 0,000 0,37394017 0,38096834 GO:0006874|cellular calcium ion homeostasis, ! ribosome biogenesis GO:0042254 71 71 0,000 0,37394017 0,38075786 ! muscle system process GO:0003012 72 72 0,000 0,37807773 0,38475829 ! sensory organ development GO:0007423 72 72 0,000 0,37807773 0,38454595 ! response to extracellular stimulus GO:0009991 72 72 0,000 0,37807773 0,38433385 ! regulation of cytokine production GO:0001817 72 72 0,000 0,37807773 0,38412197 ! electron transport chain GO:0022900 75 74 0,000 0,38627281 0,39223184 ! coenzyme metabolic process GO:0006732 75 74 0,000 0,38627281 0,39201586 ! ribonucleotide biosynthetic process GO:0009260 75 75 0,000 0,39033066 0,39591602 ! purine ribonucleotide metabolic process GO:0009150 75 75 0,000 0,39033066 0,39569825 ! positive regulation of multicellular organismal process GO:0051240 76 76 0,000 0,39436227 0,39956551 ! cellular metal ion homeostasis GO:0006875 77 77 0,000 0,39836781 0,40340213 ! metal ion homeostasis GO:0055065 78 78 0,000 0,40234745 0,40720832 ! nuclear transport GO:0051169 79 79 0,000 0,40630134 0,41098429 GO:0006913|nucleocytoplasmic transport, ! glycoprotein biosynthetic process GO:0009101 80 80 0,000 0,41022965 0,41473025 ! lymphocyte activation GO:0046649 82 81 0,000 0,41413254 0,41844642 ! lipid catabolic process GO:0016042 82 81 0,000 0,41413254 0,41821714 ! ribonucleotide metabolic process GO:0009259 83 83 0,000 0,42186271 0,42579024 ! ncRNA processing GO:0034470 83 83 0,000 0,42186271 0,42555719 ! nitrogen compound biosynthetic process GO:0044271 86 85 0,000 0,42949313 0,43301741 ! positive regulation of cell differentiation GO:0045597 87 85 0,000 0,42949313 0,43278066 ! hexose metabolic process GO:0019318 87 86 0,000 0,43327132 0,4363492 ! male gamete generation GO:0048232 90 88 0,000 0,44075445 0,44364306 GO:0007283|spermatogenesis, ! purine nucleotide biosynthetic process GO:0006164 88 88 0,000 0,44075445 0,4434009 ! cellular di-, tri-valent inorganic cation homeostasis GO:0030005 89 89 0,000 0,4444597 0,44688446 ! regulation of Ras protein signal transduction GO:0046578 90 90 0,000 0,44814094 0,4503401 ! di-, tri-valent inorganic cation homeostasis GO:0055066 91 91 0,000 0,45179833 0,45376802 ! visual perception GO:0007601 93 92 0,000 0,45543201 0,45716841 GO:0050953|sensory perception of light stimulus, ! fatty acid metabolic process GO:0006631 93 92 0,000 0,45543201 0,45691954 ! regulation of response to stress GO:0080134 97 94 0,000 0,46262886 0,46388737 ! cofactor metabolic process GO:0051186 95 94 0,000 0,46262886 0,46363513 ! endocytosis GO:0006897 99 98 0,000 0,47674467 0,47752197 GO:0010324|membrane invagination, ! glycoprotein metabolic process GO:0009100 99 98 0,000 0,47674467 0,47726259 ! negative regulation of transcription from RNA polymerase II promoter GO:0000122 103 100 0,000 0,48366596 0,48392854 ! hemopoiesis GO:0030097 104 100 0,000 0,48366596 0,48366596