pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6798-Schmidt-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! induction of positive chemotaxis GO:0050930 14 8 3,000 5,877E-08 1,352E-04 ! phosphoinositide 3-kinase cascade GO:0014065 23 8 3,000 5,877E-08 6,759E-05 ! glucan biosynthetic process GO:0009250 13 10 3,000 1,748E-07 1,34E-04 GO:0005978|glycogen biosynthetic process, ! insulin receptor signaling pathway GO:0008286 40 24 4,000 1,759E-07 1,011E-04 ! regulation of positive chemotaxis GO:0050926 17 11 3,000 2,736E-07 1,258E-04 GO:0050927|positive regulation of positive chemotaxis, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 5,000 1,019E-06 3,906E-04 ! cellular response to insulin stimulus GO:0032869 52 34 4,000 1,103E-06 3,623E-04 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 5,000 1,123E-06 3,229E-04 ! glycogen metabolic process GO:0005977 48 35 4,000 1,281E-06 3,273E-04 ! glucan metabolic process GO:0044042 49 36 4,000 1,481E-06 3,406E-04 GO:0006073|cellular glucan metabolic process, ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 5,000 1,489E-06 3,114E-04 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 5,000 1,489E-06 2,855E-04 ! centrosome duplication GO:0051298 5 5 2,000 1,592E-06 2,817E-04 ! positive regulation of ligase activity GO:0051351 99 69 5,000 2,124E-06 3,489E-04 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 3,000 2,463E-06 3,777E-04 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 5,000 2,515E-06 3,615E-04 ! induction of apoptosis by intracellular signals GO:0008629 67 40 4,000 2,54E-06 3,437E-04 ! energy reserve metabolic process GO:0006112 59 41 4,000 2,881E-06 3,681E-04 ! regulation of ligase activity GO:0051340 114 75 5,000 3,474E-06 4,206E-04 ! response to insulin stimulus GO:0032868 63 43 4,000 3,668E-06 4,219E-04 ! positive regulation of locomotion GO:0040017 35 20 3,000 3,867E-06 4,235E-04 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! cellular polysaccharide biosynthetic process GO:0033692 26 21 3,000 4,757E-06 4,973E-04 ! regulation of chemotaxis GO:0050920 36 21 3,000 4,757E-06 4,757E-04 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 5,000 5,072E-06 4,86E-04 GO:0010498|proteasomal protein catabolic process, ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 2,000 5,528E-06 5,086E-04 ! regulation of behavior GO:0050795 38 22 3,000 5,79E-06 5,122E-04 ! cellular polysaccharide metabolic process GO:0044264 63 48 4,000 6,385E-06 5,439E-04 ! negative regulation of phosphorylation GO:0042326 41 23 3,000 6,979E-06 5,733E-04 ! positive regulation of cell migration GO:0030335 92 51 4,000 8,647E-06 6,858E-04 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 2,000 8,809E-06 6,754E-04 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 3,000 9,887E-06 7,335E-04 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 3,000 9,887E-06 7,106E-04 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of insulin receptor signaling pathway GO:0046626 13 9 2,000 1,316E-05 9,173E-04 ! positive regulation of cell motion GO:0051272 99 56 4,000 1,376E-05 9,308E-04 ! negative regulation of protein kinase activity GO:0006469 99 57 4,000 1,502E-05 9,869E-04 ! response to peptide hormone stimulus GO:0043434 84 57 4,000 1,502E-05 9,594E-04 ! negative regulation of kinase activity GO:0033673 100 58 4,000 1,636E-05 1,017E-03 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 4,000 1,934E-05 1,17E-03 ! negative regulation of ligase activity GO:0051352 91 61 4,000 2,097E-05 1,237E-03 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! negative regulation of transferase activity GO:0051348 105 61 4,000 2,097E-05 1,206E-03 ! mammary gland development GO:0030879 57 31 3,000 2,398E-05 1,345E-03 ! chondrocyte differentiation GO:0002062 17 11 2,000 2,565E-05 1,404E-03 ! negative regulation of glucose import GO:0046325 14 11 2,000 2,565E-05 1,372E-03 GO:0010829|negative regulation of glucose transport, ! polysaccharide biosynthetic process GO:0000271 47 35 3,000 3,924E-05 2,051E-03 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 2,000 4,41E-05 2,254E-03 ! cellular response to hormone stimulus GO:0032870 109 74 4,000 5,368E-05 2,684E-03 ! regulation of epithelial cell proliferation GO:0050678 71 39 3,000 6,061E-05 2,966E-03 ! carbohydrate biosynthetic process GO:0016051 97 77 4,000 6,499E-05 3,114E-03 ! positive regulation of response to external stimulus GO:0032103 65 40 3,000 6,706E-05 3,148E-03 ! centrosome cycle GO:0007098 16 15 2,000 6,96E-05 3,202E-03 ! regulation of the force of heart contraction GO:0002026 21 15 2,000 6,96E-05 3,139E-03 ! neutrophil chemotaxis GO:0030593 21 16 2,000 8,532E-05 3,774E-03 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 3,000 8,942E-05 3,881E-03 ! phosphatidylinositol metabolic process GO:0046488 22 17 2,000 1,032E-04 4,395E-03 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 2,000 1,032E-04 4,315E-03 ! inactivation of MAPK activity GO:0000188 27 17 2,000 1,032E-04 4,238E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 2,000 1,032E-04 4,164E-03 ! protein amino acid autophosphorylation GO:0046777 80 45 3,000 1,071E-04 4,245E-03 ! response to UV GO:0009411 75 46 3,000 1,168E-04 4,552E-03 ! regulation of glucose import GO:0046324 21 18 2,000 1,233E-04 4,728E-03 GO:0010827|regulation of glucose transport, ! calcium-independent cell-cell adhesion GO:0016338 21 19 2,000 1,459E-04 5,501E-03 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 2,000 1,459E-04 5,412E-03 ! positive regulation of intracellular transport GO:0032388 29 19 2,000 1,459E-04 5,326E-03 ! cartilage development GO:0051216 70 49 3,000 1,497E-04 5,38E-03 ! polysaccharide metabolic process GO:0005976 129 93 4,000 1,595E-04 5,645E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 2,000 1,709E-04 5,957E-03 ! positive regulation of inflammatory response GO:0050729 30 20 2,000 1,709E-04 5,868E-03 ! response to light stimulus GO:0009416 153 96 4,000 1,852E-04 6,264E-03 ! skeletal system morphogenesis GO:0048705 78 53 3,000 2,035E-04 6,782E-03 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 4,000 2,139E-04 7,029E-03 ! microtubule organizing center organization GO:0031023 28 22 2,000 2,291E-04 7,421E-03 GO:0051297|centrosome organization, ! sleep GO:0030431 11 5 1,000 2,952E-04 9,431E-03 ! negative regulation of bone resorption GO:0045779 10 5 1,000 2,952E-04 9,302E-03 ! positive regulation of glycolysis GO:0045821 11 5 1,000 2,952E-04 9,176E-03 ! microvillus organization GO:0032528 7 5 1,000 2,952E-04 9,054E-03 GO:0030033|microvillus assembly, ! polyol catabolic process GO:0046174 7 5 1,000 2,952E-04 8,935E-03 GO:0019405|alditol catabolic process, ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 1,000 2,952E-04 8,819E-03 ! negative regulation of gliogenesis GO:0014014 16 5 1,000 2,952E-04 8,705E-03 GO:0045686|negative regulation of glial cell differentiation, ! response to UV-C GO:0010225 6 5 1,000 2,952E-04 8,595E-03 ! cranial nerve morphogenesis GO:0021602 6 5 1,000 2,952E-04 8,488E-03 ! regulation of respiratory burst GO:0060263 8 5 1,000 2,952E-04 8,383E-03 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 1,000 2,952E-04 8,281E-03 ! regulation of sensory perception GO:0051931 6 5 1,000 2,952E-04 8,181E-03 GO:0051930|regulation of sensory perception of pain, ! phosphoinositide metabolic process GO:0030384 87 60 3,000 3,29E-04 9,009E-03 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 2,000 3,807E-04 0,01030065 ! negative regulation of protein modification process GO:0031400 50 26 2,000 3,807E-04 0,01018087 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 3,000 3,969E-04 0,01049274 ! cytokinesis during cell cycle GO:0033205 9 6 1,000 4,413E-04 0,0115329 ! male meiosis GO:0007140 7 6 1,000 4,413E-04 0,01140332 ! regulation of protein export from nucleus GO:0046825 6 6 1,000 4,413E-04 0,01127662 ! N-terminal protein amino acid acetylation GO:0006474 7 6 1,000 4,413E-04 0,0111527 ! mRNA stabilization GO:0048255 15 6 1,000 4,413E-04 0,01103147 GO:0043489|RNA stabilization, ! activation of MAPKKK activity GO:0000185 10 6 1,000 4,413E-04 0,01091285 ! ER overload response GO:0006983 7 6 1,000 4,413E-04 0,01079676 ! cerebral cortex neuron differentiation GO:0021895 12 6 1,000 4,413E-04 0,01068311 ! male sex determination GO:0030238 9 6 1,000 4,413E-04 0,01057183 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 1,000 4,413E-04 0,01046284 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! blastocyst growth GO:0001832 15 6 1,000 4,413E-04 0,01035608 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 1,000 4,413E-04 0,01025147 ! negative regulation of MAP kinase activity GO:0043407 54 28 2,000 4,759E-04 0,01094459 ! embryonic skeletal system morphogenesis GO:0048704 42 30 2,000 5,851E-04 0,01332315 ! positive regulation of phosphorylation GO:0042327 102 70 3,000 5,933E-04 0,0133784 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 1,000 6,156E-04 0,01374532 ! glycerol-3-phosphate metabolic process GO:0006072 9 7 1,000 6,156E-04 0,01361315 ! regulation of lipid kinase activity GO:0043550 12 7 1,000 6,156E-04 0,01348351 ! regulation of smooth muscle cell migration GO:0014910 19 7 1,000 6,156E-04 0,0133563 ! microtubule bundle formation GO:0001578 8 7 1,000 6,156E-04 0,01323148 ! T-helper 1 type immune response GO:0042088 11 7 1,000 6,156E-04 0,01310896 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 1,000 6,156E-04 0,0129887 ! positive regulation of mitotic cell cycle GO:0045931 11 7 1,000 6,156E-04 0,01287062 ! protein heterooligomerization GO:0051291 10 7 1,000 6,156E-04 0,01275467 ! neuroblast proliferation GO:0007405 13 7 1,000 6,156E-04 0,01264079 ! leukocyte chemotaxis GO:0030595 43 31 2,000 6,452E-04 0,0131319 GO:0060326|cell chemotaxis, ! positive regulation of phosphorus metabolic process GO:0010562 107 72 3,000 6,602E-04 0,01331908 GO:0045937|positive regulation of phosphate metabolic process, ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 1,000 8,178E-04 0,01635597 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 1,000 8,178E-04 0,01621498 ! positive regulation of B cell proliferation GO:0030890 11 8 1,000 8,178E-04 0,01607639 ! Golgi to endosome transport GO:0006895 16 8 1,000 8,178E-04 0,01594015 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 1,000 8,178E-04 0,01580619 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 1,000 8,178E-04 0,01567448 ! positive regulation of endothelial cell migration GO:0010595 18 8 1,000 8,178E-04 0,01554493 ! multicellular organism growth GO:0035264 14 8 1,000 8,178E-04 0,01541752 ! regulation of vascular permeability GO:0043114 12 8 1,000 8,178E-04 0,01529217 ! regulation of gliogenesis GO:0014013 20 8 1,000 8,178E-04 0,01516885 GO:0045685|regulation of glial cell differentiation, ! regulation of T cell differentiation in the thymus GO:0033081 12 8 1,000 8,178E-04 0,0150475 ! regulation of embryonic development GO:0045995 16 8 1,000 8,178E-04 0,01492807 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 1,000 8,178E-04 0,01481053 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 2,000 8,487E-04 0,01525045 ! gland development GO:0048732 148 77 3,000 8,504E-04 0,01516255 ! regulation of intracellular protein transport GO:0033157 59 35 2,000 9,246E-04 0,01635848 ! regulation of developmental growth GO:0048638 13 9 1,000 1,048E-03 0,01839465 ! positive regulation of glucose metabolic process GO:0010907 15 9 1,000 1,048E-03 0,0182553 ! regulation of glycolysis GO:0006110 15 9 1,000 1,048E-03 0,01811804 ! lung alveolus development GO:0048286 17 9 1,000 1,048E-03 0,01798283 ! indolalkylamine metabolic process GO:0006586 14 9 1,000 1,048E-03 0,01784962 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! motor axon guidance GO:0008045 14 9 1,000 1,048E-03 0,01771838 ! response to amine stimulus GO:0014075 13 9 1,000 1,048E-03 0,01758904 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! oocyte differentiation GO:0009994 12 9 1,000 1,048E-03 0,01746159 GO:0048599|oocyte development, ! localization within membrane GO:0051668 15 9 1,000 1,048E-03 0,01733596 ! microtubule cytoskeleton organization GO:0000226 120 84 3,000 1,178E-03 0,01934627 ! Golgi vesicle transport GO:0048193 138 85 3,000 1,231E-03 0,0200737 ! positive regulation of MAP kinase activity GO:0043406 121 85 3,000 1,231E-03 0,01993234 ! anterior/posterior pattern formation GO:0009952 124 85 3,000 1,231E-03 0,01979295 ! interphase of mitotic cell cycle GO:0051329 156 86 3,000 1,285E-03 0,02052846 ! regulation of B cell proliferation GO:0030888 15 10 1,000 1,305E-03 0,02069901 ! regulation of cell projection assembly GO:0060491 20 10 1,000 1,305E-03 0,02055723 ! hippocampus development GO:0021766 19 10 1,000 1,305E-03 0,02041739 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 1,000 1,305E-03 0,02027943 ! blood vessel remodeling GO:0001974 21 10 1,000 1,305E-03 0,02014333 ! peptide or protein amino-terminal blocking GO:0018409 14 10 1,000 1,305E-03 0,02000904 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 1,000 1,305E-03 0,01987653 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 1,000 1,305E-03 0,01974576 ! response to X-ray GO:0010165 16 10 1,000 1,305E-03 0,01961671 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 1,000 1,305E-03 0,01948933 ! regulation of bone resorption GO:0045124 24 10 1,000 1,305E-03 0,01936359 ! cranial nerve development GO:0021545 12 10 1,000 1,305E-03 0,01923946 ! positive regulation of leukocyte migration GO:0002687 23 10 1,000 1,305E-03 0,01911692 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 1,000 1,305E-03 0,01899592 GO:0043470|regulation of carbohydrate catabolic process, ! positive regulation of protein transport GO:0051222 55 40 2,000 1,368E-03 0,01979342 ! interphase GO:0051325 159 88 3,000 1,4E-03 0,02011961 ! reproductive developmental process GO:0003006 127 89 3,000 1,459E-03 0,02084842 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 2,000 1,577E-03 0,02239466 ! embryonic skeletal system development GO:0048706 56 42 2,000 1,577E-03 0,02225727 ! virus-host interaction GO:0019048 17 11 1,000 1,589E-03 0,0222879 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 1,000 1,589E-03 0,02215282 ! double-strand break repair via homologous recombination GO:0000724 16 11 1,000 1,589E-03 0,02201937 GO:0000725|recombinational repair, ! positive regulation of endothelial cell proliferation GO:0001938 18 11 1,000 1,589E-03 0,02188752 ! cellular carbohydrate catabolic process GO:0044275 13 11 1,000 1,589E-03 0,02175724 ! actin cytoskeleton reorganization GO:0031532 21 11 1,000 1,589E-03 0,0216285 ! regulation of leukocyte migration GO:0002685 24 11 1,000 1,589E-03 0,02150127 ! negative regulation of mast cell proliferation GO:0070667 17 11 1,000 1,589E-03 0,02137553 GO:0042130|negative regulation of T cell proliferation, ! glycerophospholipid metabolic process GO:0006650 130 92 3,000 1,649E-03 0,02205509 ! regulation of gene-specific transcription GO:0032583 69 43 2,000 1,689E-03 0,02245436 ! leukocyte migration GO:0050900 60 43 2,000 1,689E-03 0,02232531 ! peptidyl-amino acid modification GO:0018193 147 93 3,000 1,716E-03 0,02255702 ! induction of apoptosis by extracellular signals GO:0008624 74 44 2,000 1,805E-03 0,02359295 ! regulation of inflammatory response GO:0050727 60 44 2,000 1,805E-03 0,02345966 ! regulation of mast cell proliferation GO:0070666 64 44 2,000 1,805E-03 0,02332786 ! angiogenesis GO:0001525 149 95 3,000 1,856E-03 0,02384592 ! positive regulation of cellular catabolic process GO:0031331 22 12 1,000 1,9E-03 0,02428107 ! cartilage condensation GO:0001502 18 12 1,000 1,9E-03 0,02414692 ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 1,000 1,9E-03 0,02401424 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! histone acetylation GO:0016573 23 12 1,000 1,9E-03 0,02388302 ! autonomic nervous system development GO:0048483 23 12 1,000 1,9E-03 0,02375322 ! peptidyl-lysine modification GO:0018205 18 12 1,000 1,9E-03 0,02362482 ! response to gamma radiation GO:0010332 20 12 1,000 1,9E-03 0,02349781 ! regulation of mRNA stability GO:0043488 27 12 1,000 1,9E-03 0,02337215 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 1,000 1,9E-03 0,02324783 ! positive regulation of cell cycle GO:0045787 77 45 2,000 1,927E-03 0,02344639 ! positive regulation of defense response GO:0031349 59 45 2,000 1,927E-03 0,02332299 ! regulation of response to external stimulus GO:0032101 139 96 3,000 1,928E-03 0,02322242 ! regulation of leukocyte proliferation GO:0070663 71 47 2,000 2,184E-03 0,02616566 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! N-terminal protein amino acid modification GO:0031365 18 13 1,000 2,238E-03 0,02666737 ! positive regulation of protein import into nucleus GO:0042307 23 13 1,000 2,238E-03 0,02652991 ! regulation of monooxygenase activity GO:0032768 26 13 1,000 2,238E-03 0,02639386 ! regulation of RNA stability GO:0043487 28 13 1,000 2,238E-03 0,0262592 ! regulation of muscle contraction GO:0006937 69 48 2,000 2,321E-03 0,0270942 ! regulation of DNA replication GO:0006275 75 48 2,000 2,321E-03 0,02695736 ! regulation of intracellular transport GO:0032386 78 49 2,000 2,462E-03 0,02845831 ! regulation of S phase GO:0033261 18 14 1,000 2,601E-03 0,02991587 ! phosphoinositide phosphorylation GO:0046854 21 14 1,000 2,601E-03 0,02976703 ! negative regulation of bone remodeling GO:0046851 26 14 1,000 2,601E-03 0,02961967 ! limbic system development GO:0021761 25 14 1,000 2,601E-03 0,02947376 ! startle response GO:0001964 21 14 1,000 2,601E-03 0,02932928 ! activation of MAPKK activity GO:0000186 21 14 1,000 2,601E-03 0,02918621 ! negative regulation of microtubule depolymerization GO:0007026 31 14 1,000 2,601E-03 0,02904453 GO:0031114|regulation of microtubule depolymerization, ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 2,000 2,761E-03 0,0306801 ! lipid phosphorylation GO:0046834 23 15 1,000 2,991E-03 0,03307228 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 1,000 2,991E-03 0,03291404 ! peptidyl-serine phosphorylation GO:0018105 23 15 1,000 2,991E-03 0,0327573 ! negative regulation of tissue remodeling GO:0034104 27 15 1,000 2,991E-03 0,03260205 ! dopamine metabolic process GO:0042417 30 15 1,000 2,991E-03 0,03244827 ! negative regulation of leukocyte proliferation GO:0070664 25 15 1,000 2,991E-03 0,03229593 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 1,000 2,991E-03 0,03214502 ! regulation of glucose metabolic process GO:0010906 22 16 1,000 3,406E-03 0,0364359 ! protein amino acid acetylation GO:0006473 28 16 1,000 3,406E-03 0,03626721 ! oogenesis GO:0048477 23 16 1,000 3,406E-03 0,03610008 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 1,000 3,406E-03 0,03593448 ! sperm-egg recognition GO:0035036 16 16 1,000 3,406E-03 0,0357704 GO:0007339|binding of sperm to zona pellucida, ! nerve development GO:0021675 18 16 1,000 3,406E-03 0,03560781 ! negative regulation of translation GO:0017148 22 16 1,000 3,406E-03 0,03544669 ! negative regulation of response to stimulus GO:0048585 80 56 2,000 3,603E-03 0,03733355 ! glycerol metabolic process GO:0006071 20 17 1,000 3,846E-03 0,0396707 ! signal complex assembly GO:0007172 29 17 1,000 3,846E-03 0,0394936 ! memory GO:0007613 25 17 1,000 3,846E-03 0,03931808 ! neuromuscular junction development GO:0007528 23 17 1,000 3,846E-03 0,0391441 ! negative regulation of protein catabolic process GO:0042177 26 17 1,000 3,846E-03 0,03897166 ! peptidyl-serine modification GO:0018209 27 17 1,000 3,846E-03 0,03880073 ! negative regulation of homeostatic process GO:0032845 28 17 1,000 3,846E-03 0,0386313 ! lung development GO:0030324 94 59 2,000 4,176E-03 0,04176282 ! positive regulation of DNA replication GO:0045740 29 18 1,000 4,312E-03 0,04293042 ! visual learning GO:0008542 35 18 1,000 4,312E-03 0,04274538 ! somitogenesis GO:0001756 24 18 1,000 4,312E-03 0,04256192 ! negative regulation of neuron differentiation GO:0045665 24 18 1,000 4,312E-03 0,04238003 ! cell-cell recognition GO:0009988 20 18 1,000 4,312E-03 0,04219969 ! negative regulation of T cell activation GO:0050868 25 18 1,000 4,312E-03 0,04202088 ! regulation of heart contraction GO:0008016 91 60 2,000 4,379E-03 0,04249439 ! cell-matrix adhesion GO:0007160 114 61 2,000 4,587E-03 0,04432932 ! respiratory tube development GO:0030323 99 62 2,000 4,801E-03 0,04620579 ! positive regulation of fibroblast proliferation GO:0048146 27 19 1,000 4,802E-03 0,04601729 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 1,000 4,802E-03 0,04582635 ! regulation of carbohydrate metabolic process GO:0006109 28 19 1,000 4,802E-03 0,04563698 GO:0010675|regulation of cellular carbohydrate metabolic process, ! regulation of postsynaptic membrane potential GO:0060078 30 19 1,000 4,802E-03 0,04544918 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 1,000 4,802E-03 0,04526291 ! cellular response to reactive oxygen species GO:0034614 27 19 1,000 4,802E-03 0,04507816 ! sex determination GO:0007530 29 19 1,000 4,802E-03 0,04489492 ! regulation of endothelial cell migration GO:0010594 40 19 1,000 4,802E-03 0,04471316 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 1,000 4,802E-03 0,04453286 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 2,000 5,248E-03 0,04847402 ! respiratory system development GO:0060541 100 64 2,000 5,248E-03 0,04828012 ! pallium development GO:0021543 38 20 1,000 5,316E-03 0,0487155 ! microtubule-based transport GO:0010970 37 20 1,000 5,316E-03 0,04852219 ! response to ethanol GO:0045471 37 20 1,000 5,316E-03 0,0483304 ! positive regulation of B cell activation GO:0050871 31 20 1,000 5,316E-03 0,04814012 ! alditol metabolic process GO:0019400 24 20 1,000 5,316E-03 0,04795134 ! protein oligomerization GO:0051259 100 65 2,000 5,48E-03 0,04923546 ! cell-substrate adhesion GO:0031589 121 66 2,000 5,718E-03 0,05117721 ! G2/M transition of mitotic cell cycle GO:0000086 33 21 1,000 5,855E-03 0,05219618 ! gluconeogenesis GO:0006094 25 21 1,000 5,855E-03 0,05199465 ! protein amino acid acylation GO:0043543 37 21 1,000 5,855E-03 0,05179467 ! vesicle docking GO:0048278 27 21 1,000 5,855E-03 0,05159622 ! dendrite development GO:0016358 35 21 1,000 5,855E-03 0,05139929 ! visual behavior GO:0007632 39 21 1,000 5,855E-03 0,05120385 ! cell aging GO:0007569 32 21 1,000 5,855E-03 0,0510099 ! response to endoplasmic reticulum stress GO:0034976 25 21 1,000 5,855E-03 0,05081741 ! cellular response to extracellular stimulus GO:0031668 32 21 1,000 5,855E-03 0,05062637 ! regulation of fibroblast proliferation GO:0048145 35 22 1,000 6,418E-03 0,05528308 ! spliceosomal snRNP biogenesis GO:0000387 28 22 1,000 6,418E-03 0,0550768 ! glutamate signaling pathway GO:0007215 34 22 1,000 6,418E-03 0,05487205 ! vasculogenesis GO:0001570 33 22 1,000 6,418E-03 0,05466883 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 1,000 6,418E-03 0,0544671 ! membrane depolarization GO:0051899 35 22 1,000 6,418E-03 0,05426685 ! blastocyst development GO:0001824 37 22 1,000 6,418E-03 0,05406807 ! protein tetramerization GO:0051262 39 22 1,000 6,418E-03 0,05387074 ! regulation of catabolic process GO:0009894 106 70 2,000 6,734E-03 0,05631879 ! positive regulation of cell adhesion GO:0045785 37 23 1,000 7,004E-03 0,05836548 ! myelination GO:0042552 35 23 1,000 7,004E-03 0,05815477 ! regulation of transcription factor import into nucleus GO:0042990 46 23 1,000 7,004E-03 0,05794558 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 1,000 7,004E-03 0,05773789 ! ER-nuclear signaling pathway GO:0006984 27 23 1,000 7,004E-03 0,05753168 ! negative regulation of DNA replication GO:0008156 35 23 1,000 7,004E-03 0,05732695 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 1,000 7,004E-03 0,05712366 ! interaction with host GO:0051701 37 23 1,000 7,004E-03 0,05692181 ! cellular response to oxidative stress GO:0034599 33 23 1,000 7,004E-03 0,05672138 ! negative regulation of catabolic process GO:0009895 34 23 1,000 7,004E-03 0,05652236 ! response to hypoxia GO:0001666 132 72 2,000 7,279E-03 0,05853749 ! negative regulation of transport GO:0051051 116 73 2,000 7,561E-03 0,06059465 ! positive regulation of cell projection organization GO:0031346 39 24 1,000 7,613E-03 0,06080159 ! regulation of cellular catabolic process GO:0031329 36 24 1,000 7,613E-03 0,0605912 ! pyruvate metabolic process GO:0006090 29 24 1,000 7,613E-03 0,06038227 ! regulation of endothelial cell proliferation GO:0001936 46 24 1,000 7,613E-03 0,06017477 ! negative regulation of cell development GO:0010721 56 24 1,000 7,613E-03 0,05996869 GO:0050768|negative regulation of neurogenesis, ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 1,000 7,613E-03 0,05976402 ! regulation of oxidoreductase activity GO:0051341 39 24 1,000 7,613E-03 0,05956074 ! response to oxygen levels GO:0070482 137 74 2,000 7,85E-03 0,0612011 ! peptidyl-tyrosine modification GO:0018212 37 25 1,000 8,246E-03 0,06407406 ! negative regulation of lymphocyte activation GO:0051250 37 25 1,000 8,246E-03 0,06385832 ! regulation of protein transport GO:0051223 114 76 2,000 8,446E-03 0,06518822 GO:0070201|regulation of establishment of protein localization, ! sex differentiation GO:0007548 105 77 2,000 8,754E-03 0,06733893 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 1,000 8,902E-03 0,06824484 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 1,000 8,902E-03 0,06801811 ! positive regulation of protein modification process GO:0031401 107 78 2,000 9,069E-03 0,06906486 ! membrane docking GO:0022406 39 27 1,000 9,579E-03 0,07271565 ! catechol metabolic process GO:0009712 43 27 1,000 9,579E-03 0,07247645 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! response to ionizing radiation GO:0010212 47 27 1,000 9,579E-03 0,07223882 ! negative regulation of leukocyte activation GO:0002695 39 27 1,000 9,579E-03 0,07200275 ! phenol metabolic process GO:0018958 44 28 1,000 0,01027978 0,07701461 ! response to organic cyclic substance GO:0014070 47 28 1,000 0,01027978 0,07676456 ! ensheathment of neurons GO:0007272 43 28 1,000 0,01027978 0,07651613 GO:0008366|axon ensheathment, ! positive regulation of catabolic process GO:0009896 40 28 1,000 0,01027978 0,07626931 ! regulation of B cell activation GO:0050864 42 28 1,000 0,01027978 0,07602407 ! ossification GO:0001503 134 82 2,000 0,01039212 0,07660854 GO:0060348|bone development, ! regulation of protein import into nucleus GO:0042306 53 29 1,000 0,01100208 0,08084597 ! telencephalon development GO:0021537 52 29 1,000 0,01100208 0,0805885 ! hexose biosynthetic process GO:0019319 35 29 1,000 0,01100208 0,08033266 ! regulation of defense response GO:0031347 117 84 2,000 0,01109373 0,08074553 ! regulation of DNA metabolic process GO:0051052 135 85 2,000 0,01145458 0,08310894 ! regulation of protein localization GO:0032880 132 85 2,000 0,01145458 0,08284759 ! regulation of membrane potential GO:0042391 128 85 2,000 0,01145458 0,08258788 ! hindbrain development GO:0030902 45 30 1,000 0,01174615 0,08442549 ! regulation of microtubule-based process GO:0032886 58 30 1,000 0,01174615 0,08416248 ! negative regulation of cell activation GO:0050866 44 30 1,000 0,01174615 0,08390111 ! skeletal muscle tissue development GO:0007519 123 87 2,000 0,01219645 0,0868478 GO:0060538|skeletal muscle organ development, ! segmentation GO:0035282 41 31 1,000 0,01251174 0,0888179 ! negative regulation of DNA metabolic process GO:0051053 48 32 1,000 0,01329858 0,09411305 ! regulation of synaptic plasticity GO:0048167 52 32 1,000 0,01329858 0,09382436 ! peripheral nervous system development GO:0007422 53 32 1,000 0,01329858 0,09353743 ! calcium-mediated signaling GO:0019722 50 32 1,000 0,01329858 0,09325226 ! monosaccharide biosynthetic process GO:0046364 38 32 1,000 0,01329858 0,09296881 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 1,000 0,01329858 0,09268709 ! positive regulation of DNA metabolic process GO:0051054 54 33 1,000 0,01410643 0,09802053 ! carbohydrate homeostasis GO:0033500 39 33 1,000 0,01410643 0,09772528 GO:0042593|glucose homeostasis, ! female gonad development GO:0008585 49 33 1,000 0,01410643 0,09743181 ! cytokinesis GO:0000910 52 33 1,000 0,01410643 0,0971401 ! female gamete generation GO:0007292 43 34 1,000 0,01493504 0,10253908 ! polyol metabolic process GO:0019751 44 34 1,000 0,01493504 0,1022339 ! dorsal/ventral pattern formation GO:0009953 44 34 1,000 0,01493504 0,10193053 ! regulation of action potential in neuron GO:0019228 54 35 1,000 0,01578416 0,10740698 ! positive regulation of leukocyte proliferation GO:0070665 50 35 1,000 0,01578416 0,10709015 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! protein homooligomerization GO:0051260 52 35 1,000 0,01578416 0,10677517 ! positive regulation of transcription factor activity GO:0051091 49 36 1,000 0,01665354 0,11232591 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 55 36 1,000 0,01665354 0,11199748 ! tissue remodeling GO:0048771 62 36 1,000 0,01665354 0,11167095 ! development of primary female sexual characteristics GO:0046545 52 36 1,000 0,01665354 0,11134633 GO:0046660|female sex differentiation, ! learning GO:0007612 67 37 1,000 0,01754294 0,11695294 ! homophilic cell adhesion GO:0007156 149 100 2,000 0,01768321 0,11754733 ! Ras protein signal transduction GO:0007265 162 100 2,000 0,01768321 0,11720857 ! alcohol biosynthetic process GO:0046165 45 38 1,000 0,01845212 0,12195369 ! regulation of T cell proliferation GO:0042129 58 38 1,000 0,01845212 0,12160425 ! negative regulation of protein complex disassembly GO:0043242 67 39 1,000 0,01938085 0,12735986 ! developmental growth GO:0048589 62 39 1,000 0,01938085 0,12699701 ! synapse organization GO:0050808 55 39 1,000 0,01938085 0,12663622 ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 1,000 0,02032887 0,13245443 ! double-strand break repair GO:0006302 67 40 1,000 0,02032887 0,13208026 ! glucose transport GO:0015758 52 41 1,000 0,02129597 0,13797389 ! endosome transport GO:0016197 71 41 1,000 0,02129597 0,13758633 ! positive regulation of DNA binding GO:0043388 57 41 1,000 0,02129597 0,13720093 ! regulation of T cell differentiation GO:0045580 59 41 1,000 0,02129597 0,13681769 ! hexose transport GO:0008645 54 42 1,000 0,0222819 0,14275313 GO:0015749|monosaccharide transport, ! regulation of gene expression, epigenetic GO:0040029 72 42 1,000 0,0222819 0,14235659 ! regulation of cell shape GO:0008360 78 42 1,000 0,0222819 0,14196225 ! positive regulation of binding GO:0051099 59 43 1,000 0,02328643 0,14795249 ! neuromuscular process GO:0050905 79 43 1,000 0,02328643 0,1475449 ! DNA-dependent DNA replication GO:0006261 59 43 1,000 0,02328643 0,14713956 ! regulation of cell projection organization GO:0031344 83 44 1,000 0,02430934 0,15318216 ! regulation of action potential GO:0001508 71 44 1,000 0,02430934 0,15276363 ! negative regulation of cell migration GO:0030336 92 44 1,000 0,02430934 0,15234738 ! vascular process in circulatory system GO:0003018 69 45 1,000 0,0253504 0,15843998 ! cell recognition GO:0008037 58 45 1,000 0,0253504 0,1580106 ! cell maturation GO:0048469 60 45 1,000 0,0253504 0,15758354 ! regulation of protein complex disassembly GO:0043244 77 46 1,000 0,02640937 0,16372386 ! histone modification GO:0016570 68 46 1,000 0,02640937 0,16328374 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 0,02715999 0,16747445 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 0,02715999 0,16702666 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 0,02715999 0,16658125 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 0,02715999 0,16613822 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 0,02715999 0,16569753 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02715999 0,16525918 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 0,02715999 0,16482314 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 0,02715999 0,16438939 ! nucleotide-sugar transport GO:0015780 8 5 0,000 0,02715999 0,16395793 ! regulation of interferon-beta production GO:0032648 5 5 0,000 0,02715999 0,16352872 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 0,02715999 0,16310175 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 0,02715999 0,162677 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 0,02715999 0,16225447 ! tongue development GO:0043586 6 5 0,000 0,02715999 0,16183412 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 0,02715999 0,16141594 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,02715999 0,16099992 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 0,02715999 0,16058604 ! cobalt ion transport GO:0006824 9 5 0,000 0,02715999 0,16017428 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 0,02715999 0,15976463 ! SMAD protein complex assembly GO:0007183 9 5 0,000 0,02715999 0,15935706 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 0,02715999 0,15895158 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 0,02715999 0,15854815 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 0,02715999 0,15814676 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 0,02715999 0,1577474 ! embryonic camera-type eye development GO:0031076 8 5 0,000 0,02715999 0,15735005 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 0,02715999 0,1569547 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 0,02715999 0,15656133 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02715999 0,15616992 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,02715999 0,15578047 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,02715999 0,15539296 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 0,000 0,02715999 0,15500737 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 0,02715999 0,15462369 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,02715999 0,1542419 ! malate metabolic process GO:0006108 7 5 0,000 0,02715999 0,15386199 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 0,02715999 0,15348395 ! behavioral response to pain GO:0048266 7 5 0,000 0,02715999 0,15310777 ! clathrin coat assembly GO:0048268 11 5 0,000 0,02715999 0,15273342 ! phototransduction, visible light GO:0007603 6 5 0,000 0,02715999 0,1523609 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02715999 0,15199019 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 0,02715999 0,15162129 ! mating behavior GO:0007617 6 5 0,000 0,02715999 0,15125416 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,02715999 0,15088882 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 0,02715999 0,15052523 ! rhythmic behavior GO:0007622 12 5 0,000 0,02715999 0,15016339 ! copulation GO:0007620 7 5 0,000 0,02715999 0,14980328 ! glial cell fate commitment GO:0021781 12 5 0,000 0,02715999 0,1494449 ! protein maturation by protein folding GO:0022417 12 5 0,000 0,02715999 0,14908823 ! embryonic hemopoiesis GO:0035162 10 5 0,000 0,02715999 0,14873326 ! regulation of potassium ion transport GO:0043266 9 5 0,000 0,02715999 0,14837997 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 0,02715999 0,14802836 ! apoptotic cell clearance GO:0043277 13 5 0,000 0,02715999 0,14767841 ! lipoprotein particle clearance GO:0034381 9 5 0,000 0,02715999 0,14733012 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 0,02715999 0,14698346 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02715999 0,14663843 ! response to protozoan GO:0001562 9 5 0,000 0,02715999 0,14629501 ! lymph vessel development GO:0001945 7 5 0,000 0,02715999 0,1459532 ! endochondral ossification GO:0001958 12 5 0,000 0,02715999 0,14561298 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 0,02715999 0,14527435 ! parathyroid gland development GO:0060017 8 5 0,000 0,02715999 0,14493728 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 0,02715999 0,14460178 ! anagen GO:0042640 6 5 0,000 0,02715999 0,14426783 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 0,02715999 0,14393541 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 0,02715999 0,14360453 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 0,02715999 0,14327516 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! nuclear migration GO:0007097 10 5 0,000 0,02715999 0,1429473 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 0,02715999 0,14262093 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 0,02715999 0,14229606 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 0,02715999 0,14197266 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 0,02715999 0,14165072 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 0,02715999 0,14133025 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 0,02715999 0,14101122 ! cardiac muscle fiber development GO:0048739 7 5 0,000 0,02715999 0,14069362 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 0,02715999 0,14037746 ! negative regulation of survival gene product expression GO:0008634 6 5 0,000 0,02715999 0,14006271 ! neutrophil mediated immunity GO:0002446 6 5 0,000 0,02715999 0,13974937 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 0,02715999 0,13943743 ! ovulation GO:0030728 6 5 0,000 0,02715999 0,13912688 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 0,02715999 0,13881771 GO:0033135|regulation of peptidyl-serine phosphorylation, ! valine metabolic process GO:0006573 8 5 0,000 0,02715999 0,13850991 ! response to pH GO:0009268 9 5 0,000 0,02715999 0,13820347 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 0,02715999 0,13789839 ! proline biosynthetic process GO:0006561 6 5 0,000 0,02715999 0,13759465 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,02715999 0,13729224 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 0,02715999 0,13699116 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,02715999 0,1366914 ! polyol biosynthetic process GO:0046173 5 5 0,000 0,02715999 0,13639295 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,02715999 0,13609579 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,02715999 0,13579993 ! sister chromatid cohesion GO:0007062 9 5 0,000 0,02715999 0,13550536 ! nerve growth factor processing GO:0032455 7 5 0,000 0,02715999 0,13521206 ! urea metabolic process GO:0019627 6 5 0,000 0,02715999 0,13492002 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 0,02715999 0,13462924 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,02715999 0,13433972 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 0,000 0,02715999 0,13405144 ! neutrophil activation GO:0042119 5 5 0,000 0,02715999 0,13376439 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 0,02715999 0,13347857 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 0,02715999 0,13319396 ! response to food GO:0032094 5 5 0,000 0,02715999 0,13291057 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 0,02715999 0,13262839 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02715999 0,13234739 ! paraxial mesoderm development GO:0048339 9 5 0,000 0,02715999 0,13206759 ! forebrain neuron development GO:0021884 7 5 0,000 0,02715999 0,13178897 ! melanosome organization GO:0032438 7 5 0,000 0,02715999 0,13151151 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 0,02715999 0,13123523 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,02715999 0,1309601 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 0,02715999 0,13068613 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02715999 0,1304133 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 14 5 0,000 0,02715999 0,1301416 ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 0,02715999 0,12987104 ! nucleoside transport GO:0015858 6 5 0,000 0,02715999 0,1296016 ! nucleoside salvage GO:0043174 7 5 0,000 0,02715999 0,12933327 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 0,02715999 0,12906605 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02715999 0,12879994 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 0,02715999 0,12853492 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 0,02715999 0,12827098 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,02715999 0,12800813 ! early endosome to late endosome transport GO:0045022 11 5 0,000 0,02715999 0,12774636 ! depyrimidination GO:0045008 8 5 0,000 0,02715999 0,12748565 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 0,02715999 0,12722601 ! 5S class rRNA transcription GO:0042791 8 5 0,000 0,02715999 0,12696742 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 0,02715999 0,12670988 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02715999 0,12645338 ! neuronal ion channel clustering GO:0045161 7 5 0,000 0,02715999 0,12619792 ! sodium ion homeostasis GO:0055078 6 5 0,000 0,02715999 0,12594349 ! homeostasis of number of cells within a tissue GO:0048873 9 5 0,000 0,02715999 0,12569008 ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 0,02715999 0,12543769 ! monocyte differentiation GO:0030224 8 5 0,000 0,02715999 0,12518631 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 0,02715999 0,12493594 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02715999 0,12468657 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 0,02715999 0,12443819 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 0,02715999 0,12419079 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 0,02715999 0,12394438 ! regulation of dendrite development GO:0050773 12 5 0,000 0,02715999 0,12369895 ! peptidyl-arginine modification GO:0018195 7 5 0,000 0,02715999 0,12345449 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02715999 0,12321099 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 0,02715999 0,12296844 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 0,02715999 0,12272686 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 0,02715999 0,12248621 ! regulation of dopamine secretion GO:0014059 12 5 0,000 0,02715999 0,12224652 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 0,02715999 0,12200775 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 0,02715999 0,12176992 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,02715999 0,12153301 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 0,02715999 0,12129703 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,02715999 0,12106196 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 0,02715999 0,12082779 ! positive regulation of Rho GTPase activity GO:0032321 9 5 0,000 0,02715999 0,12059454 ! neural tube patterning GO:0021532 6 5 0,000 0,02715999 0,12036218 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 0,02715999 0,12013071 ! histone demethylation GO:0016577 9 5 0,000 0,02715999 0,11990013 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,02715999 0,11967044 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02715999 0,11944162 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 0,02715999 0,11921368 ! enteric nervous system development GO:0048484 8 5 0,000 0,02715999 0,11898661 ! establishment of planar polarity GO:0001736 6 5 0,000 0,02715999 0,1187604 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 0,02715999 0,11853505 ! muscle cell proliferation GO:0033002 8 5 0,000 0,02715999 0,11831055 ! transcription termination GO:0006353 8 5 0,000 0,02715999 0,1180869 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 0,02715999 0,11786409 ! positive regulation of pseudopodium assembly GO:0031274 13 5 0,000 0,02715999 0,11764213 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 5 5 0,000 0,02715999 0,117421 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 0,02715999 0,11720069 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,02715999 0,11698122 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,02715999 0,11676256 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 0,02715999 0,11654472 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 0,02715999 0,11632769 ! apical protein localization GO:0045176 6 5 0,000 0,02715999 0,11611147 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 0,02715999 0,11589605 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 0,02715999 0,11568142 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02715999 0,1154676 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02715999 0,11525456 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 0,02715999 0,1150423 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 0,02715999 0,11483083 ! triglyceride catabolic process GO:0019433 6 5 0,000 0,02715999 0,11462013 ! glial cell migration GO:0008347 10 5 0,000 0,02715999 0,1144102 ! determination of adult lifespan GO:0008340 8 5 0,000 0,02715999 0,11420104 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 0,02715999 0,11399265 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,02715999 0,11378501 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,02715999 0,11357813 ! somatic stem cell maintenance GO:0035019 13 5 0,000 0,02715999 0,113372 ! cerebellar cortex formation GO:0021697 6 5 0,000 0,02715999 0,11316661 ! neural plate development GO:0001840 6 5 0,000 0,02715999 0,11296197 ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 0,02715999 0,11275807 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 0,02715999 0,1125549 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 10 5 0,000 0,02715999 0,11235246 ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 0,02715999 0,11215075 ! sensory cilium assembly GO:0035058 6 5 0,000 0,02715999 0,11194977 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 0,02715999 0,1117495 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,02715999 0,11154995 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 0,02715999 0,1113511 ! spindle assembly GO:0051225 5 5 0,000 0,02715999 0,11115297 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 0,02715999 0,11095554 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 0,02715999 0,11075881 ! protein amino acid prenylation GO:0018346 9 5 0,000 0,02715999 0,11056278 ! organ regeneration GO:0031100 7 5 0,000 0,02715999 0,11036744 ! NAD biosynthetic process GO:0009435 7 5 0,000 0,02715999 0,11017279 ! carnitine metabolic process GO:0009437 5 5 0,000 0,02715999 0,10997882 GO:0006577|betaine metabolic process, ! positive regulation of microtubule polymerization GO:0031116 9 5 0,000 0,02715999 0,10978554 ! cellular anion homeostasis GO:0030002 6 5 0,000 0,02715999 0,10959293 GO:0055081|anion homeostasis, ! response to estrogen stimulus GO:0043627 74 47 1,000 0,02748604 0,11071436 ! covalent chromatin modification GO:0016569 75 47 1,000 0,02748604 0,1105208 ! negative regulation of immune system process GO:0002683 73 47 1,000 0,02748604 0,11032792 ! heart morphogenesis GO:0003007 65 48 1,000 0,02858019 0,11451992 ! regulation of lymphocyte differentiation GO:0045619 69 48 1,000 0,02858019 0,11432075 ! regulation of angiogenesis GO:0045765 94 49 1,000 0,02969159 0,11856017 ! germ cell development GO:0007281 68 49 1,000 0,02969159 0,11835469 ! integrin-mediated signaling pathway GO:0007229 81 49 1,000 0,02969159 0,11814992 ! skeletal muscle fiber development GO:0048741 73 50 1,000 0,03082003 0,12242843 ! negative regulation of cytoskeleton organization GO:0051494 84 50 1,000 0,03082003 0,12221735 ! lipid modification GO:0030258 73 50 1,000 0,03082003 0,12200699 ! positive regulation of growth GO:0045927 67 50 1,000 0,03082003 0,12179736 ! activation of phospholipase C activity GO:0007202 87 51 1,000 0,03196529 0,12610661 GO:0010863|positive regulation of phospholipase C activity, ! muscle fiber development GO:0048747 74 51 1,000 0,03196529 0,12589068 ! regulation of protein catabolic process GO:0042176 77 51 1,000 0,03196529 0,12567548 ! negative regulation of cell motion GO:0051271 104 51 1,000 0,03196529 0,12546102 ! tRNA transcription GO:0009304 11 6 0,000 0,03250373 0,12735704 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 0,03250373 0,12714045 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 8 6 0,000 0,03250373 0,12692459 ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 0,03250373 0,12670946 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,03250373 0,12649507 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 0,03250373 0,12628139 ! regulation of helicase activity GO:0051095 11 6 0,000 0,03250373 0,12606844 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 0,03250373 0,1258562 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 0,03250373 0,12564468 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 0,03250373 0,12543387 ! positive regulation of axon extension GO:0045773 8 6 0,000 0,03250373 0,12522376 ! prostate gland development GO:0030850 9 6 0,000 0,03250373 0,12501435 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 0,03250373 0,12480565 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 0,03250373 0,12459764 ! forebrain neuron differentiation GO:0021879 9 6 0,000 0,03250373 0,12439032 GO:0021872|generation of neurons in the forebrain, ! regulation of lipid catabolic process GO:0050994 9 6 0,000 0,03250373 0,12418369 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 0,03250373 0,12397775 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 0,03250373 0,12377249 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 0,03250373 0,12356791 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 0,03250373 0,123364 ! neuron adhesion GO:0007158 9 6 0,000 0,03250373 0,12316076 ! establishment of tissue polarity GO:0007164 7 6 0,000 0,03250373 0,1229582 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 0,03250373 0,1227563 ! signal peptide processing GO:0006465 8 6 0,000 0,03250373 0,12255506 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 0,03250373 0,12235448 ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 0,03250373 0,12215455 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 0,03250373 0,12195528 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 0,03250373 0,12175665 ! opsonization GO:0008228 8 6 0,000 0,03250373 0,12155867 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 0,03250373 0,12136134 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 0,03250373 0,12116464 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 0,03250373 0,12096858 ! protein amino acid dealkylation GO:0008214 11 6 0,000 0,03250373 0,12077316 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 0,03250373 0,12057836 ! photoreceptor cell development GO:0042461 10 6 0,000 0,03250373 0,12038419 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 0,03250373 0,12019065 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 0,03250373 0,11999773 ! mechanosensory behavior GO:0007638 8 6 0,000 0,03250373 0,11980542 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 0,03250373 0,11961373 ! negative regulation of endocytosis GO:0045806 8 6 0,000 0,03250373 0,11942266 ! response to interferon-gamma GO:0034341 12 6 0,000 0,03250373 0,11923219 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 0,03250373 0,11904233 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 0,03250373 0,11885308 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,03250373 0,11866442 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 0,03250373 0,11847636 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 0,03250373 0,1182889 ! cGMP-mediated signaling GO:0019934 10 6 0,000 0,03250373 0,11810203 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 0,03250373 0,11791575 ! thymic T cell selection GO:0045061 12 6 0,000 0,03250373 0,11773005 ! protein lipoylation GO:0009249 10 6 0,000 0,03250373 0,11754494 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 0,03250373 0,11736041 ! pigment granule organization GO:0048753 11 6 0,000 0,03250373 0,11717646 ! drug transport GO:0015893 6 6 0,000 0,03250373 0,11699309 ! cysteine metabolic process GO:0006534 7 6 0,000 0,03250373 0,11681029 ! activation of caspase activity by cytochrome c GO:0008635 10 6 0,000 0,03250373 0,11662806 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 0,03250373 0,11644639 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,03250373 0,11626529 ! histidine metabolic process GO:0006547 6 6 0,000 0,03250373 0,11608476 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 0,03250373 0,11590478 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 0,03250373 0,11572536 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 0,000 0,03250373 0,1155465 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! glycine catabolic process GO:0006546 9 6 0,000 0,03250373 0,11536819 ! adenohypophysis development GO:0021984 10 6 0,000 0,03250373 0,11519042 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 0,03250373 0,11501321 ! hyperosmotic response GO:0006972 8 6 0,000 0,03250373 0,11483653 ! microtubule nucleation GO:0007020 10 6 0,000 0,03250373 0,11466041 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 0,03250373 0,11448482 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 0,03250373 0,11430976 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 0,03250373 0,11413524 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 0,03250373 0,11396126 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 0,03250373 0,1137878 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 0,000 0,03250373 0,11361487 ! response to dietary excess GO:0002021 7 6 0,000 0,03250373 0,11344246 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 0,03250373 0,11327058 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 0,03250373 0,11309922 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 0,03250373 0,11292838 ! glycerol ether catabolic process GO:0044269 8 6 0,000 0,03250373 0,11275805 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 0,03250373 0,11258823 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,03250373 0,11241892 ! neuron apoptosis GO:0051402 8 6 0,000 0,03250373 0,11225013 ! organic alcohol transport GO:0015850 9 6 0,000 0,03250373 0,11208184 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 0,000 0,03250373 0,11191405 ! T cell mediated immunity GO:0002456 12 6 0,000 0,03250373 0,11174676 ! carnitine transport GO:0015879 8 6 0,000 0,03250373 0,11157998 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 0,03250373 0,11141369 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 0,03250373 0,11124789 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,03250373 0,11108259 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 0,03250373 0,11091778 ! positive regulation of exocytosis GO:0045921 6 6 0,000 0,03250373 0,11075346 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 0,03250373 0,11058962 ! parturition GO:0007567 12 6 0,000 0,03250373 0,11042627 ! negative regulation of translational initiation GO:0045947 7 6 0,000 0,03250373 0,1102634 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 0,03250373 0,11010101 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 0,03250373 0,10993909 ! spindle checkpoint GO:0031577 14 6 0,000 0,03250373 0,10977766 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 0,03250373 0,10961669 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 0,03250373 0,1094562 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 0,03250373 0,10929618 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 0,03250373 0,10913662 ! macrophage differentiation GO:0030225 10 6 0,000 0,03250373 0,10897753 ! astrocyte development GO:0014002 14 6 0,000 0,03250373 0,1088189 ! hyaluronan metabolic process GO:0030212 6 6 0,000 0,03250373 0,10866073 ! purine base biosynthetic process GO:0009113 14 6 0,000 0,03250373 0,10850303 ! interaction with symbiont GO:0051702 8 6 0,000 0,03250373 0,10834577 ! anterograde axon cargo transport GO:0008089 8 6 0,000 0,03250373 0,10818898 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,03250373 0,10803264 ! eating behavior GO:0042755 6 6 0,000 0,03250373 0,10787674 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 0,03250373 0,1077213 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 0,03250373 0,10756631 ! response to copper ion GO:0046688 9 6 0,000 0,03250373 0,10741176 ! DNA topological change GO:0006265 8 6 0,000 0,03250373 0,10725765 ! response to exogenous dsRNA GO:0043330 8 6 0,000 0,03250373 0,10710399 ! enucleate erythrocyte differentiation GO:0043353 9 6 0,000 0,03250373 0,10695076 ! establishment of melanosome localization GO:0032401 9 6 0,000 0,03250373 0,10679798 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,03250373 0,10664563 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,03250373 0,10649371 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 0,03250373 0,10634223 ! negative regulation of focal adhesion formation GO:0051895 16 6 0,000 0,03250373 0,10619117 ! nucleoside catabolic process GO:0009164 6 6 0,000 0,03250373 0,10604055 ! gas homeostasis GO:0033483 11 6 0,000 0,03250373 0,10589035 ! hair follicle maturation GO:0048820 7 6 0,000 0,03250373 0,10574057 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 0,03250373 0,10559122 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 0,03250373 0,10544229 ! Schwann cell development GO:0014044 14 6 0,000 0,03250373 0,10529378 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 0,03250373 0,10514569 ! dendrite morphogenesis GO:0048813 9 6 0,000 0,03250373 0,10499801 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,03250373 0,10485075 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 0,03250373 0,1047039 ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 0,03250373 0,10455746 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 0,03250373 0,10441143 ! histone ubiquitination GO:0016574 7 6 0,000 0,03250373 0,10426581 ! regulation of meiosis GO:0040020 10 6 0,000 0,03250373 0,10412059 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 0,03250373 0,10397578 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 0,03250373 0,10383137 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 0,03250373 0,10368736 ! regulation of mast cell activation GO:0033003 6 6 0,000 0,03250373 0,10354375 ! membrane to membrane docking GO:0022614 12 6 0,000 0,03250373 0,10340053 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 0,03250373 0,10325771 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 0,03250373 0,10311529 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 0,03250373 0,10297326 ! receptor internalization GO:0031623 9 6 0,000 0,03250373 0,10283162 ! neutrophil homeostasis GO:0001780 6 6 0,000 0,03250373 0,10269036 ! coenzyme A metabolic process GO:0015936 9 6 0,000 0,03250373 0,1025495 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,03250373 0,10240902 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 0,000 0,03250373 0,10226893 ! protein deubiquitination GO:0016579 8 6 0,000 0,03250373 0,10212921 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 0,03250373 0,10198988 ! negative regulation of neuroblast proliferation GO:0007406 18 6 0,000 0,03250373 0,10185093 ! peptidyl-histidine modification GO:0018202 9 6 0,000 0,03250373 0,10171236 ! axonal fasciculation GO:0007413 9 6 0,000 0,03250373 0,10157416 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 0,03250373 0,10143634 ! thiamin metabolic process GO:0006772 6 6 0,000 0,03250373 0,10129889 ! midbrain development GO:0030901 6 6 0,000 0,03250373 0,10116182 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 0,03250373 0,10102511 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,03250373 0,10088878 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 0,03250373 0,10075281 ! progesterone metabolic process GO:0042448 8 6 0,000 0,03250373 0,10061721 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 0,03250373 0,10048197 ! glycolipid catabolic process GO:0019377 13 6 0,000 0,03250373 0,10034709 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 0,03250373 0,10021258 ! positive regulation of glucose import GO:0046326 6 6 0,000 0,03250373 0,10007843 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 0,03250373 0,09994463 ! adult feeding behavior GO:0008343 6 6 0,000 0,03250373 0,09981119 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 0,03250373 0,09967811 ! pigment granule transport GO:0051904 12 6 0,000 0,03250373 0,09954539 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 0,03250373 0,09941301 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 0,03250373 0,09928099 ! catecholamine transport GO:0051937 7 6 0,000 0,03250373 0,09914932 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,03250373 0,09901799 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 0,03250373 0,09888702 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 0,03250373 0,09875639 ! negative regulation of B cell activation GO:0050869 9 6 0,000 0,03250373 0,0986261 ! protein prenylation GO:0018342 10 6 0,000 0,03250373 0,09849616 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,03250373 0,09836656 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 0,000 0,03250373 0,0982373 ! regulation of microtubule polymerization GO:0031113 11 6 0,000 0,03250373 0,09810838 ! positive regulation of coagulation GO:0050820 11 6 0,000 0,03250373 0,0979798 ! positive regulation of phospholipase activity GO:0010518 88 52 1,000 0,03312715 0,09972833 ! aging GO:0007568 79 52 1,000 0,03312715 0,09959796 ! nucleotide-excision repair GO:0006289 64 52 1,000 0,03312715 0,09946794 ! regulation of bone remodeling GO:0046850 90 53 1,000 0,03430541 0,10287149 ! single fertilization GO:0007338 59 53 1,000 0,03430541 0,10273754 ! cell projection assembly GO:0030031 76 53 1,000 0,03430541 0,10260394 ! amino acid transport GO:0006865 84 54 1,000 0,03549984 0,10603849 ! regulation of phospholipase activity GO:0010517 90 54 1,000 0,03549984 0,10590096 ! cytokine-mediated signaling pathway GO:0019221 76 54 1,000 0,03549984 0,10576378 ! regulation of tissue remodeling GO:0034103 91 54 1,000 0,03549984 0,10562696 ! positive regulation of lipase activity GO:0060193 90 54 1,000 0,03549984 0,10549049 ! exocytosis GO:0006887 74 55 1,000 0,03671025 0,10894656 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 0,03781843 0,1120907 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 0,03781843 0,11194644 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 0,03781843 0,11180255 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 0,03781843 0,11165903 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 0,03781843 0,11151588 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,03781843 0,11137309 GO:0070193|synaptonemal complex organization, ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,03781843 0,11123067 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 0,03781843 0,11108862 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 0,03781843 0,11094692 ! reproductive behavior GO:0019098 12 7 0,000 0,03781843 0,11080559 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 0,03781843 0,11066461 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 0,03781843 0,110524 ! oligopeptide transport GO:0006857 11 7 0,000 0,03781843 0,11038374 ! protein amino acid sulfation GO:0006477 9 7 0,000 0,03781843 0,11024384 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 0,03781843 0,11010429 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! negative regulation of JAK-STAT cascade GO:0046426 15 7 0,000 0,03781843 0,10996509 ! RNA methylation GO:0001510 11 7 0,000 0,03781843 0,10982625 ! pericardium development GO:0060039 8 7 0,000 0,03781843 0,10968775 ! macrophage chemotaxis GO:0048246 10 7 0,000 0,03781843 0,10954961 ! fibril organization GO:0043206 13 7 0,000 0,03781843 0,10941181 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 0,03781843 0,10927436 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,03781843 0,10913725 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 0,03781843 0,10900048 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 0,03781843 0,10886406 ! lipoprotein transport GO:0042953 9 7 0,000 0,03781843 0,10872798 ! cerebral cortex cell migration GO:0021795 11 7 0,000 0,03781843 0,10859224 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,03781843 0,10845684 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,03781843 0,10832178 ! estrogen metabolic process GO:0008210 14 7 0,000 0,03781843 0,10818705 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 0,03781843 0,10805265 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 0,03781843 0,10791859 ! chemosensory behavior GO:0007635 9 7 0,000 0,03781843 0,10778487 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 0,03781843 0,10765147 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 0,03781843 0,1075184 ! leukocyte degranulation GO:0043299 10 7 0,000 0,03781843 0,10738566 ! bile acid and bile salt transport GO:0015721 9 7 0,000 0,03781843 0,10725325 ! reflex GO:0060004 12 7 0,000 0,03781843 0,10712117 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,03781843 0,10698941 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 0,03781843 0,10685797 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,03781843 0,10672686 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 0,03781843 0,10659606 ! glycerolipid catabolic process GO:0046503 9 7 0,000 0,03781843 0,10646559 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,03781843 0,10633544 ! spinal cord patterning GO:0021511 7 7 0,000 0,03781843 0,1062056 ! hemoglobin metabolic process GO:0020027 10 7 0,000 0,03781843 0,10607608 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 0,03781843 0,10594688 ! adrenal gland development GO:0030325 17 7 0,000 0,03781843 0,10581799 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 0,03781843 0,10568941 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 0,03781843 0,10556115 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 0,03781843 0,1054332 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 0,03781843 0,10530555 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 0,03781843 0,10517822 ! endosome organization GO:0007032 10 7 0,000 0,03781843 0,10505119 ! thyroid hormone generation GO:0006590 11 7 0,000 0,03781843 0,10492447 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 0,03781843 0,10479806 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 0,03781843 0,10467195 ! regulation of pigmentation during development GO:0048070 15 7 0,000 0,03781843 0,10454614 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,03781843 0,10442063 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 0,03781843 0,10429543 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,03781843 0,10417052 ! galactose metabolic process GO:0006012 10 7 0,000 0,03781843 0,10404592 ! vesicle fusion GO:0006906 15 7 0,000 0,03781843 0,10392161 ! intracellular pH reduction GO:0051452 10 7 0,000 0,03781843 0,1037976 GO:0045851|pH reduction, ! asymmetric protein localization GO:0008105 8 7 0,000 0,03781843 0,10367388 ! organ growth GO:0035265 11 7 0,000 0,03781843 0,10355046 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 0,03781843 0,10342733 ! Rac protein signal transduction GO:0016601 7 7 0,000 0,03781843 0,1033045 ! retinol metabolic process GO:0042572 9 7 0,000 0,03781843 0,10318195 ! behavioral fear response GO:0001662 13 7 0,000 0,03781843 0,1030597 GO:0002209|behavioral defense response, ! negative regulation of muscle contraction GO:0045932 12 7 0,000 0,03781843 0,10293774 ! rRNA modification GO:0000154 12 7 0,000 0,03781843 0,10281606 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,03781843 0,10269467 ! response to UV-B GO:0010224 11 7 0,000 0,03781843 0,10257357 ! G1 DNA damage checkpoint GO:0031571 18 7 0,000 0,03781843 0,10245275 ! protein retention in ER lumen GO:0006621 12 7 0,000 0,03781843 0,10233222 ! intermediate filament organization GO:0045109 11 7 0,000 0,03781843 0,10221197 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 0,03781843 0,102092 ! cardiac muscle cell development GO:0055013 9 7 0,000 0,03781843 0,10197232 ! fibrinolysis GO:0042730 9 7 0,000 0,03781843 0,10185291 ! regulation of circadian rhythm GO:0042752 11 7 0,000 0,03781843 0,10173379 ! B cell lineage commitment GO:0002326 17 7 0,000 0,03781843 0,10161494 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 0,03781843 0,10149637 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 0,03781843 0,10137807 ! response to tropane GO:0014073 13 7 0,000 0,03781843 0,10126005 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 0,03781843 0,10114231 ! melanosome localization GO:0032400 10 7 0,000 0,03781843 0,10102484 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 0,03781843 0,10090764 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 0,03781843 0,10079071 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 0,03781843 0,10067406 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 0,03781843 0,10055767 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 0,03781843 0,10044156 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 0,03781843 0,10032571 ! mast cell activation GO:0045576 9 7 0,000 0,03781843 0,10021012 ! multicellular organismal aging GO:0010259 11 7 0,000 0,03781843 0,10009481 ! regulation of focal adhesion formation GO:0051893 17 7 0,000 0,03781843 0,09997976 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 0,03781843 0,09986497 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 0,03781843 0,09975044 ! positive regulation of monooxygenase activity GO:0032770 11 7 0,000 0,03781843 0,09963618 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 0,03781843 0,09952218 ! establishment of nucleus localization GO:0040023 13 7 0,000 0,03781843 0,09940844 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 0,03781843 0,09929496 ! T cell lineage commitment GO:0002360 12 7 0,000 0,03781843 0,09918174 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 0,03781843 0,09906878 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 0,03781843 0,09895607 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 0,03781843 0,09884362 ! regulation of lipid transport GO:0032368 13 7 0,000 0,03781843 0,09873143 ! response to tumor cell GO:0002347 12 7 0,000 0,03781843 0,09861949 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 0,03781843 0,0985078 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 0,03781843 0,09839637 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 0,000 0,03781843 0,09828518 ! peptidyl-threonine modification GO:0018210 18 7 0,000 0,03781843 0,09817425 ! diuresis GO:0030146 12 7 0,000 0,03781843 0,09806357 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 0,03781843 0,09795314 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of epidermis development GO:0045684 11 7 0,000 0,03781843 0,09784295 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,03781843 0,09773302 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 0,03781843 0,09762333 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,03781843 0,09751389 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,03781843 0,09740469 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,03781843 0,09729573 ! regulation of synaptogenesis GO:0051963 10 7 0,000 0,03781843 0,09718702 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 0,03781843 0,09707856 ! dopamine biosynthetic process GO:0042416 15 7 0,000 0,03781843 0,09697033 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 0,03781843 0,09686235 ! lymph node development GO:0048535 9 7 0,000 0,03781843 0,0967546 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 0,03781843 0,0966471 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 0,03781843 0,09653983 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,03781843 0,0964328 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 0,03781843 0,09632601 ! endosome to lysosome transport GO:0008333 10 7 0,000 0,03781843 0,09621945 ! ATP catabolic process GO:0006200 10 7 0,000 0,03781843 0,09611313 ! establishment of pigment granule localization GO:0051905 13 7 0,000 0,03781843 0,09600705 ! trophectodermal cell differentiation GO:0001829 8 7 0,000 0,03781843 0,0959012 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 0,03781843 0,09579558 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 0,03781843 0,09569019 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 0,03781843 0,09558504 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 0,03781843 0,09548012 ! muscle adaptation GO:0043500 12 7 0,000 0,03781843 0,09537542 ! amino sugar catabolic process GO:0046348 9 7 0,000 0,03781843 0,09527096 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 0,03781843 0,09516673 ! retina homeostasis GO:0001895 9 7 0,000 0,03781843 0,09506272 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 0,03781843 0,09495894 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 0,03781843 0,09485538 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 0,03781843 0,09475206 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 0,03781843 0,09464895 ! behavioral response to nicotine GO:0035095 11 7 0,000 0,03781843 0,09454607 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 0,03781843 0,09444342 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,03781843 0,09434098 ! DNA damage response, signal transduction GO:0042770 96 56 1,000 0,03793643 0,09453282 ! regulation of lipid metabolic process GO:0019216 84 56 1,000 0,03793643 0,09443051 ! carbohydrate transport GO:0008643 74 57 1,000 0,03917817 0,09741598 ! developmental maturation GO:0021700 75 57 1,000 0,03917817 0,09731078 ! gonad development GO:0008406 79 57 1,000 0,03917817 0,09720581 ! viral reproductive process GO:0022415 87 58 1,000 0,04043526 0,10021669 ! activation of MAPK activity GO:0000187 84 59 1,000 0,0417075 0,10325862 ! myeloid cell differentiation GO:0030099 85 59 1,000 0,0417075 0,10314759 ! fertilization GO:0009566 68 60 1,000 0,0429947 0,10621677 ! regulation of homeostatic process GO:0032844 105 60 1,000 0,0429947 0,1061028 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 0,04310423 0,1062591 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,04310423 0,10614533 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! axon extension GO:0048675 11 8 0,000 0,04310423 0,1060318 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 0,04310423 0,10591852 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 0,000 0,04310423 0,10580548 GO:0046579|positive regulation of Ras protein signal transduction, ! associative learning GO:0008306 15 8 0,000 0,04310423 0,10569268 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,04310423 0,10558012 ! cell proliferation in forebrain GO:0021846 10 8 0,000 0,04310423 0,10546781 ! phosphate transport GO:0006817 10 8 0,000 0,04310423 0,10535572 ! N-glycan processing GO:0006491 12 8 0,000 0,04310423 0,10524388 ! UTP metabolic process GO:0046051 8 8 0,000 0,04310423 0,10513228 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 0,04310423 0,10502091 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 0,04310423 0,10490977 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 10 8 0,000 0,04310423 0,10479888 ! succinate metabolic process GO:0006105 14 8 0,000 0,04310423 0,10468821 ! smoothened signaling pathway GO:0007224 8 8 0,000 0,04310423 0,10457778 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,04310423 0,10446758 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 0,000 0,04310423 0,10435762 ! keratinocyte proliferation GO:0043616 12 8 0,000 0,04310423 0,10424788 ! middle ear morphogenesis GO:0042474 9 8 0,000 0,04310423 0,10413838 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,04310423 0,1040291 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 0,04310423 0,10392006 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,04310423 0,10381124 ! ganglioside metabolic process GO:0001573 15 8 0,000 0,04310423 0,10370265 ! pseudouridine synthesis GO:0001522 9 8 0,000 0,04310423 0,10359429 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,04310423 0,10348616 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,04310423 0,10337824 ! endothelial cell differentiation GO:0045446 14 8 0,000 0,04310423 0,10327056 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,04310423 0,1031631 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 0,000 0,04310423 0,10305586 ! astrocyte differentiation GO:0048708 16 8 0,000 0,04310423 0,10294884 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 0,04310423 0,10284205 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,04310423 0,10273548 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,04310423 0,10262913 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 0,04310423 0,102523 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,04310423 0,10241708 ! melanin metabolic process GO:0006582 12 8 0,000 0,04310423 0,10231139 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 0,04310423 0,10220591 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,04310423 0,10210066 ! macrophage activation GO:0042116 12 8 0,000 0,04310423 0,10199561 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,04310423 0,10189079 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,04310423 0,10178618 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 0,04310423 0,10168178 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 0,04310423 0,1015776 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 0,04310423 0,10147363 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 0,04310423 0,10136987 ! ruffle organization GO:0031529 11 8 0,000 0,04310423 0,10126633 ! osteoblast development GO:0002076 13 8 0,000 0,04310423 0,101163 ! lens development in camera-type eye GO:0002088 10 8 0,000 0,04310423 0,10105987 ! positive regulation of vasodilation GO:0045909 12 8 0,000 0,04310423 0,10095696 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,04310423 0,10085426 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 0,04310423 0,10075177 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 0,04310423 0,10064948 ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 0,04310423 0,1005474 ! Schwann cell differentiation GO:0014037 17 8 0,000 0,04310423 0,10044553 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,04310423 0,10034386 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 0,04310423 0,1002424 ! brain morphogenesis GO:0048854 20 8 0,000 0,04310423 0,10014115 ! oligodendrocyte development GO:0014003 8 8 0,000 0,04310423 0,1000401 ! segment specification GO:0007379 10 8 0,000 0,04310423 0,09993925 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 0,000 0,04310423 0,09983861 ! cellular extravasation GO:0045123 11 8 0,000 0,04310423 0,09973817 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 0,04310423 0,09963793 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 0,04310423 0,09953789 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 0,04310423 0,09943805 ! snRNA metabolic process GO:0016073 10 8 0,000 0,04310423 0,09933841 GO:0016180|snRNA processing, ! regulation of interleukin-4 production GO:0032673 16 8 0,000 0,04310423 0,09923898 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 0,04310423 0,09913974 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,04310423 0,0990407 ! regulation of mitochondrial membrane potential GO:0051881 11 8 0,000 0,04310423 0,09894185 ! nucleosome disassembly GO:0006337 12 8 0,000 0,04310423 0,09884321 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 0,04310423 0,09874476 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of Ras GTPase activity GO:0032320 20 8 0,000 0,04310423 0,0986465 ! protein import into peroxisome matrix GO:0016558 14 8 0,000 0,04310423 0,09854845 ! icosanoid secretion GO:0032309 12 8 0,000 0,04310423 0,09845058 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 11 8 0,000 0,04310423 0,09835291 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,04310423 0,09825544 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 0,04310423 0,09815816 ! cerebellum morphogenesis GO:0021587 9 8 0,000 0,04310423 0,09806107 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 0,04310423 0,09796417 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 0,04310423 0,09786746 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 0,04310423 0,09777094 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 0,04310423 0,09767462 ! sterol catabolic process GO:0016127 9 8 0,000 0,04310423 0,09757848 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 0,04310423 0,09748253 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 0,04310423 0,09738677 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 0,04310423 0,0972912 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 0,04310423 0,09719582 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,04310423 0,09710062 ! prophase GO:0051324 11 8 0,000 0,04310423 0,09700561 ! S phase GO:0051320 8 8 0,000 0,04310423 0,09691079 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 0,04310423 0,09681615 ! regulation of macrophage differentiation GO:0045649 14 8 0,000 0,04310423 0,09672169 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,04310423 0,09662742 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,04310423 0,09653334 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,04310423 0,09643943 ! hormone catabolic process GO:0042447 13 8 0,000 0,04310423 0,09634571 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,04310423 0,09625217 ! myeloid cell homeostasis GO:0002262 8 8 0,000 0,04310423 0,09615881 ! regulation of fibrinolysis GO:0051917 13 8 0,000 0,04310423 0,09606564 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 0,04310423 0,09597264 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,04310423 0,09587982 ! regulation of telomere maintenance GO:0032204 10 8 0,000 0,04310423 0,09578719 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,04310423 0,09569473 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,04310423 0,09560245 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 0,04310423 0,09551034 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 0,04310423 0,09541842 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,04310423 0,09532667 ! lamellipodium assembly GO:0030032 9 8 0,000 0,04310423 0,0952351 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,04310423 0,0951437 GO:0000076|DNA replication checkpoint, ! mitochondrion localization GO:0051646 12 8 0,000 0,04310423 0,09505248 ! meiosis GO:0007126 96 61 1,000 0,04429665 0,09758841 GO:0051327|M phase of meiotic cell cycle, ! negative regulation of cell growth GO:0030308 106 62 1,000 0,04561316 0,1003926 ! meiotic cell cycle GO:0051321 97 62 1,000 0,04561316 0,10029662 ! regulation of transcription factor activity GO:0051090 97 63 1,000 0,04694403 0,10312442 GO:0090046|regulation of transcription regulator activity, ! viral reproduction GO:0016032 92 63 1,000 0,04694403 0,10302602 ! regulation of lipase activity GO:0060191 109 63 1,000 0,04694403 0,10292781 ! negative regulation of cell size GO:0045792 108 64 1,000 0,04828907 0,10577606 ! adaptive immune response GO:0002250 94 64 1,000 0,04828907 0,10567541 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,0483613 0,10573288 ! telencephalon cell migration GO:0022029 16 9 0,000 0,0483613 0,10563247 ! regulation of epithelial cell differentiation GO:0030856 13 9 0,000 0,0483613 0,10553225 ! pentose-phosphate shunt GO:0006098 12 9 0,000 0,0483613 0,10543222 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 0,0483613 0,10533238 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 0,0483613 0,10523273 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,0483613 0,10513326 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! positive regulation of GTPase activity GO:0043547 21 9 0,000 0,0483613 0,10503399 ! SMAD protein nuclear translocation GO:0007184 15 9 0,000 0,0483613 0,1049349 ! GTP metabolic process GO:0046039 9 9 0,000 0,0483613 0,104836 ! elastic fiber assembly GO:0048251 13 9 0,000 0,0483613 0,10473728 ! social behavior GO:0035176 14 9 0,000 0,0483613 0,10463875 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 0,0483613 0,10454041 ! artery development GO:0060840 19 9 0,000 0,0483613 0,10444225 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 0,0483613 0,10434427 ! response to pain GO:0048265 16 9 0,000 0,0483613 0,10424648 ! protein complex disassembly GO:0043241 17 9 0,000 0,0483613 0,10414887 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,0483613 0,10405144 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,0483613 0,1039542 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 0,0483613 0,10385714 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,0483613 0,10376025 ! negative regulation of striated muscle development GO:0045843 11 9 0,000 0,0483613 0,10366355 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,0483613 0,10356703 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,0483613 0,10347069 ! ventral spinal cord development GO:0021517 11 9 0,000 0,0483613 0,10337453 ! protein targeting to ER GO:0045047 19 9 0,000 0,0483613 0,10327854 ! T cell selection GO:0045058 18 9 0,000 0,0483613 0,10318274 ! endoderm development GO:0007492 12 9 0,000 0,0483613 0,10308711 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,0483613 0,10299166 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,0483613 0,10289638 ! arginine catabolic process GO:0006527 10 9 0,000 0,0483613 0,10280129 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 0,0483613 0,10270636 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 0,0483613 0,10261162 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 0,0483613 0,10251704 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,0483613 0,10242264 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 12 9 0,000 0,0483613 0,10232842 ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 0,000 0,0483613 0,10223437 ! regulation of stress fiber formation GO:0051492 20 9 0,000 0,0483613 0,10214049 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,0483613 0,10204678 ! mannose metabolic process GO:0006013 9 9 0,000 0,0483613 0,10195325 ! substrate-bound cell migration GO:0006929 10 9 0,000 0,0483613 0,10185988 ! receptor clustering GO:0043113 15 9 0,000 0,0483613 0,10176669 ! epithelial cell development GO:0002064 10 9 0,000 0,0483613 0,10167367 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 0,0483613 0,10158081 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,0483613 0,10148813 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 0,0483613 0,10139562 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,0483613 0,10130327 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 0,0483613 0,10121109 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 0,0483613 0,10111908 ! alpha-beta T cell differentiation GO:0046632 14 9 0,000 0,0483613 0,10102724 ! positive regulation of phagocytosis GO:0050766 11 9 0,000 0,0483613 0,10093556 ! blastoderm segmentation GO:0007350 11 9 0,000 0,0483613 0,10084405 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,0483613 0,10075271 ! DNA ligation GO:0006266 14 9 0,000 0,0483613 0,10066153 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 0,0483613 0,10057052 ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 0,0483613 0,10047967 ! erythrocyte development GO:0048821 11 9 0,000 0,0483613 0,10038898 ! renal water homeostasis GO:0003091 14 9 0,000 0,0483613 0,10029846 ! postreplication repair GO:0006301 11 9 0,000 0,0483613 0,1002081 ! mRNA cleavage GO:0006379 13 9 0,000 0,0483613 0,1001179 ! hindbrain morphogenesis GO:0021575 12 9 0,000 0,0483613 0,10002787 ! regulation of hormone metabolic process GO:0032350 15 9 0,000 0,0483613 0,099938 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,0483613 0,09984829 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 0,0483613 0,09975874 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 0,0483613 0,09966935 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 0,0483613 0,09958012 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 0,000 0,0483613 0,09949105 ! acid secretion GO:0046717 14 9 0,000 0,0483613 0,09940214 ! musculoskeletal movement GO:0050881 11 9 0,000 0,0483613 0,09931339 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 0,0483613 0,09922479 ! methionine biosynthetic process GO:0009086 10 9 0,000 0,0483613 0,09913636 ! purine base metabolic process GO:0006144 18 9 0,000 0,0483613 0,09904808 ! thymus development GO:0048538 15 9 0,000 0,0483613 0,09895996 ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 0,0483613 0,09887199 ! spleen development GO:0048536 15 9 0,000 0,0483613 0,09878418 ! negative regulation of BMP signaling pathway GO:0030514 13 9 0,000 0,0483613 0,09869653 ! anterior/posterior axis specification GO:0009948 11 9 0,000 0,0483613 0,09860904 ! regulation of RNA splicing GO:0043484 14 9 0,000 0,0483613 0,09852169 ! detection of calcium ion GO:0005513 13 9 0,000 0,0483613 0,09843451 ! blastocyst formation GO:0001825 12 9 0,000 0,0483613 0,09834747 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,0483613 0,09826059 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 0,000 0,0483613 0,09817387 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 0,0483613 0,09808729 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,0483613 0,09800087 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,0483613 0,09791461 ! positive regulation of amine transport GO:0051954 15 9 0,000 0,0483613 0,09782849 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 0,0483613 0,09774252 ! prepulse inhibition GO:0060134 14 9 0,000 0,0483613 0,09765671 ! embryonic placenta development GO:0001892 12 9 0,000 0,0483613 0,09757105 ! positive regulation of protein polymerization GO:0032273 15 9 0,000 0,0483613 0,09748553 ! insulin secretion GO:0030073 17 9 0,000 0,0483613 0,09740017 ! sequestering of metal ion GO:0051238 11 9 0,000 0,0483613 0,09731495 ! response to nicotine GO:0035094 16 9 0,000 0,0483613 0,09722989 ! establishment of cell polarity GO:0030010 12 9 0,000 0,0483613 0,09714497 ! nucleus localization GO:0051647 15 9 0,000 0,0483613 0,0970602 ! regulation of synapse organization GO:0050807 12 9 0,000 0,0483613 0,09697558 ! reproductive structure development GO:0048608 90 65 1,000 0,04964808 0,09946916 ! regulation of caspase activity GO:0043281 97 65 1,000 0,04964808 0,09938259 ! axon guidance GO:0007411 99 66 1,000 0,05102088 0,10204177 ! regulation of endopeptidase activity GO:0052548 99 67 1,000 0,05240728 0,1047235 ! regulation of neuron differentiation GO:0045664 107 67 1,000 0,05240728 0,10463259 ! negative regulation of muscle development GO:0048635 12 10 0,000 0,05358979 0,1069007 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,05358979 0,10680806 ! neuron fate specification GO:0048665 11 10 0,000 0,05358979 0,10671559 ! negative regulation of blood pressure GO:0045776 22 10 0,000 0,05358979 0,10662328 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 0,05358979 0,10653112 ! thyroid gland development GO:0030878 19 10 0,000 0,05358979 0,10643912 ! regulation of phosphatase activity GO:0010921 21 10 0,000 0,05358979 0,10634729 ! synapsis GO:0007129 13 10 0,000 0,05358979 0,10625561 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 0,05358979 0,10616409 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 0,05358979 0,10607273 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,05358979 0,10598152 GO:0007520|myoblast fusion, ! hair follicle morphogenesis GO:0031069 17 10 0,000 0,05358979 0,10589047 ! sulfate transport GO:0008272 12 10 0,000 0,05358979 0,10579958 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 0,05358979 0,10570884 GO:0048200|Golgi transport vesicle coating, ! androgen metabolic process GO:0008209 13 10 0,000 0,05358979 0,10561826 ! phospholipid efflux GO:0033700 16 10 0,000 0,05358979 0,10552783 ! positive regulation of heart contraction GO:0045823 14 10 0,000 0,05358979 0,10543756 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 0,05358979 0,10534744 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 0,000 0,05358979 0,10525748 GO:0010812|negative regulation of cell-substrate adhesion, ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 0,05358979 0,10516767 ! pathogenesis GO:0009405 13 10 0,000 0,05358979 0,10507801 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,05358979 0,10498851 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,05358979 0,10489915 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 0,05358979 0,10480995 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 0,05358979 0,10472091 ! melanocyte differentiation GO:0030318 15 10 0,000 0,05358979 0,10463201 GO:0050931|pigment cell differentiation, ! polyamine metabolic process GO:0006595 14 10 0,000 0,05358979 0,10454326 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,05358979 0,10445467 ! B cell proliferation GO:0042100 14 10 0,000 0,05358979 0,10436622 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 0,05358979 0,10427792 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,05358979 0,10418978 ! forebrain cell migration GO:0021885 17 10 0,000 0,05358979 0,10410178 ! lipid digestion GO:0044241 15 10 0,000 0,05358979 0,10401393 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,05358979 0,10392623 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,05358979 0,10383867 ! UV protection GO:0009650 14 10 0,000 0,05358979 0,10375127 ! entry into host cell GO:0030260 20 10 0,000 0,05358979 0,10366401 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 16 10 0,000 0,05358979 0,1035769 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,05358979 0,10348993 ! negative regulation of ossification GO:0030279 19 10 0,000 0,05358979 0,10340311 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 0,05358979 0,10331643 ! alpha-beta T cell activation GO:0046631 16 10 0,000 0,05358979 0,10322991 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 0,05358979 0,10314352 ! regulation of organ growth GO:0046620 11 10 0,000 0,05358979 0,10305728 ! response to dsRNA GO:0043331 18 10 0,000 0,05358979 0,10297118 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 0,05358979 0,10288523 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,05358979 0,10279942 ! embryonic axis specification GO:0000578 12 10 0,000 0,05358979 0,10271376 ! regulation of B cell differentiation GO:0045577 16 10 0,000 0,05358979 0,10262823 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,05358979 0,10254285 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,05358979 0,10245761 ! fucose catabolic process GO:0019317 16 10 0,000 0,05358979 0,10237251 GO:0042355|L-fucose catabolic process, ! DNA methylation GO:0006306 15 10 0,000 0,05358979 0,10228756 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 18 10 0,000 0,05358979 0,10220274 ! protein sumoylation GO:0016925 12 10 0,000 0,05358979 0,10211807 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 0,05358979 0,10203353 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,05358979 0,10194914 ! zymogen activation GO:0031638 14 10 0,000 0,05358979 0,10186488 ! salivary gland development GO:0007431 22 10 0,000 0,05358979 0,10178077 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,05358979 0,10169679 ! glutathione biosynthetic process GO:0006750 11 10 0,000 0,05358979 0,10161295 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,05358979 0,10152925 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 0,05358979 0,10144568 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 0,05358979 0,10136226 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,05358979 0,10127897 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 0,05358979 0,10119582 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 0,05358979 0,1011128 ! positive regulation of JNK cascade GO:0046330 14 10 0,000 0,05358979 0,10102992 ! detection of bacterium GO:0016045 10 10 0,000 0,05358979 0,10094718 ! embryonic gut development GO:0048566 11 10 0,000 0,05358979 0,10086457 ! activation of innate immune response GO:0002218 10 10 0,000 0,05358979 0,1007821 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 21 10 0,000 0,05358979 0,10069976 ! cardiac cell differentiation GO:0035051 16 10 0,000 0,05358979 0,10061756 ! developmental induction GO:0031128 13 10 0,000 0,05358979 0,10053549 GO:0045168|cell-cell signaling involved in cell fate specification, ! T cell receptor signaling pathway GO:0050852 18 10 0,000 0,05358979 0,10045355 ! cytoplasmic sequestering of protein GO:0051220 14 10 0,000 0,05358979 0,10037175 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 0,05358979 0,10029008 ! negative regulation of immune effector process GO:0002698 16 10 0,000 0,05358979 0,10020854 ! learning or memory GO:0007611 123 68 1,000 0,05380709 0,10053314 ! development of primary sexual characteristics GO:0045137 92 68 1,000 0,05380709 0,10045154 ! activation of protein kinase activity GO:0032147 102 69 1,000 0,05522011 0,10300589 ! response to drug GO:0042493 108 69 1,000 0,05522011 0,10292242 ! amine transport GO:0015837 101 70 1,000 0,05664618 0,10549492 ! phosphoinositide-mediated signaling GO:0048015 109 71 1,000 0,05808511 0,10808718 ! rRNA transcription GO:0009303 17 11 0,000 0,05878984 0,10931013 ! respiratory burst GO:0045730 14 11 0,000 0,05878984 0,10922184 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 0,05878984 0,10913369 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 0,05878984 0,10904567 ! cortical cytoskeleton organization GO:0030865 20 11 0,000 0,05878984 0,1089578 ! filopodium assembly GO:0046847 19 11 0,000 0,05878984 0,10887008 ! Golgi vesicle budding GO:0048194 17 11 0,000 0,05878984 0,10878249 ! RNA polyadenylation GO:0043631 19 11 0,000 0,05878984 0,10869504 ! detection of mechanical stimulus GO:0050982 15 11 0,000 0,05878984 0,10860774 ! mating GO:0007618 14 11 0,000 0,05878984 0,10852057 ! dopamine receptor signaling pathway GO:0007212 22 11 0,000 0,05878984 0,10843355 ! T cell proliferation GO:0042098 20 11 0,000 0,05878984 0,10834666 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 0,05878984 0,10825992 ! bone resorption GO:0045453 16 11 0,000 0,05878984 0,10817331 ! regulated secretory pathway GO:0045055 14 11 0,000 0,05878984 0,10808684 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 0,05878984 0,10800051 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 0,05878984 0,10791431 ! regulation of mRNA processing GO:0050684 18 11 0,000 0,05878984 0,10782826 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 0,05878984 0,10774234 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 0,05878984 0,10765656 ! syncytium formation GO:0006949 15 11 0,000 0,05878984 0,10757091 ! plasma membrane organization GO:0007009 18 11 0,000 0,05878984 0,1074854 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,05878984 0,10740003 ! focal adhesion formation GO:0048041 24 11 0,000 0,05878984 0,10731479 ! mitotic spindle organization GO:0007052 15 11 0,000 0,05878984 0,10722969 ! regulation of intracellular pH GO:0051453 17 11 0,000 0,05878984 0,10714472 ! membrane protein proteolysis GO:0033619 18 11 0,000 0,05878984 0,10705989 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 0,05878984 0,10697519 ! adult heart development GO:0007512 11 11 0,000 0,05878984 0,10689062 ! temperature homeostasis GO:0001659 16 11 0,000 0,05878984 0,10680619 ! L-glutamate transport GO:0015813 16 11 0,000 0,05878984 0,10672189 GO:0015800|acidic amino acid transport, ! regulation of vascular endothelial growth factor production GO:0010574 19 11 0,000 0,05878984 0,10663773 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,05878984 0,10655369 ! protein targeting to peroxisome GO:0006625 20 11 0,000 0,05878984 0,10646979 ! stem cell development GO:0048864 29 11 0,000 0,05878984 0,10638602 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 0,05878984 0,10630239 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 0,05878984 0,10621888 ! regulation of phagocytosis GO:0050764 14 11 0,000 0,05878984 0,10613551 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 0,05878984 0,10605226 ! vasoconstriction GO:0042310 15 11 0,000 0,05878984 0,10596915 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 0,05878984 0,10588617 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,05878984 0,10580331 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 0,05878984 0,10572059 ! regulation of Rho GTPase activity GO:0032319 18 11 0,000 0,05878984 0,105638 ! ribosome assembly GO:0042255 13 11 0,000 0,05878984 0,10555553 ! nitric oxide metabolic process GO:0046209 14 11 0,000 0,05878984 0,10547319 GO:0006809|nitric oxide biosynthetic process, ! histone deacetylation GO:0016575 13 11 0,000 0,05878984 0,10539099 ! chromatin silencing GO:0006342 19 11 0,000 0,05878984 0,10530891 ! nucleosome positioning GO:0016584 13 11 0,000 0,05878984 0,10522695 ! T cell homeostasis GO:0043029 20 11 0,000 0,05878984 0,10514513 ! regulation of isotype switching GO:0045191 19 11 0,000 0,05878984 0,10506343 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 0,05878984 0,10498186 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,05878984 0,10490042 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 0,05878984 0,1048191 ! aromatic amino acid family catabolic process GO:0009074 13 11 0,000 0,05878984 0,10473791 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 0,05878984 0,10465684 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,05878984 0,1045759 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 0,05878984 0,10449508 ! male genitalia development GO:0030539 13 11 0,000 0,05878984 0,10441439 ! cholesterol efflux GO:0033344 19 11 0,000 0,05878984 0,10433382 ! digestive tract morphogenesis GO:0048546 15 11 0,000 0,05878984 0,10425338 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 21 11 0,000 0,05878984 0,10417306 ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 0,05878984 0,10409287 ! germ cell migration GO:0008354 18 11 0,000 0,05878984 0,1040128 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,05878984 0,10393285 ! defense response to fungus GO:0050832 12 11 0,000 0,05878984 0,10385302 ! mRNA 3'-end processing GO:0031124 19 11 0,000 0,05878984 0,10377332 ! lysogeny GO:0030069 18 11 0,000 0,05878984 0,10369374 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 0,05878984 0,10361428 ! acrosome reaction GO:0007340 13 11 0,000 0,05878984 0,10353494 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 0,05878984 0,10345573 ! regulation of peptidase activity GO:0052547 106 72 1,000 0,05953671 0,10468994 ! negative regulation of organelle organization GO:0010639 115 72 1,000 0,05953671 0,10460996 ! regulation of synaptic transmission GO:0050804 109 72 1,000 0,05953671 0,10453011 ! response to steroid hormone stimulus GO:0048545 114 73 1,000 0,06100081 0,10701897 ! positive regulation of lymphocyte activation GO:0051251 108 74 1,000 0,06247723 0,10952564 ! lactation GO:0007595 20 12 0,000 0,06396162 0,11204245 ! reproductive cellular process GO:0048610 14 12 0,000 0,06396162 0,11195718 ! tRNA modification GO:0006400 14 12 0,000 0,06396162 0,11187204 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 0,06396162 0,11178703 ! positive regulation of blood pressure GO:0045777 16 12 0,000 0,06396162 0,11170215 ! 'de novo' protein folding GO:0006458 18 12 0,000 0,06396162 0,1116174 ! dicarboxylic acid transport GO:0006835 22 12 0,000 0,06396162 0,11153278 ! non-recombinational repair GO:0000726 19 12 0,000 0,06396162 0,11144828 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 0,06396162 0,11136391 ! peroxisomal transport GO:0043574 21 12 0,000 0,06396162 0,11127968 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 0,06396162 0,11119556 ! cytokine biosynthetic process GO:0042089 16 12 0,000 0,06396162 0,11111158 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,06396162 0,11102772 ! heart looping GO:0001947 15 12 0,000 0,06396162 0,11094399 ! palate development GO:0060021 15 12 0,000 0,06396162 0,11086038 ! positive regulation of cell growth GO:0030307 16 12 0,000 0,06396162 0,11077691 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 0,06396162 0,11069355 ! regulation of skeletal muscle fiber development GO:0048742 20 12 0,000 0,06396162 0,11061032 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,06396162 0,11052722 ! arginine metabolic process GO:0006525 13 12 0,000 0,06396162 0,11044424 ! glycoprotein catabolic process GO:0006516 19 12 0,000 0,06396162 0,11036139 ! methionine metabolic process GO:0006555 13 12 0,000 0,06396162 0,11027866 ! tyrosine metabolic process GO:0006570 14 12 0,000 0,06396162 0,11019605 ! Golgi organization GO:0007030 18 12 0,000 0,06396162 0,11011357 ! cell-cell junction assembly GO:0007043 18 12 0,000 0,06396162 0,11003121 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 0,06396162 0,10994898 ! monoamine transport GO:0015844 13 12 0,000 0,06396162 0,10986686 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,06396162 0,10978487 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! neutral amino acid transport GO:0015804 19 12 0,000 0,06396162 0,10970301 ! L-amino acid transport GO:0015807 20 12 0,000 0,06396162 0,10962126 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 0,06396162 0,10953964 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,06396162 0,10945813 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 0,06396162 0,10937675 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,06396162 0,10929549 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 0,06396162 0,10921435 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 0,06396162 0,10913333 ! cerebellum development GO:0021549 13 12 0,000 0,06396162 0,10905243 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,06396162 0,10897165 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,06396162 0,10889099 ! histone methylation GO:0016571 15 12 0,000 0,06396162 0,10881045 ! gland morphogenesis GO:0022612 23 12 0,000 0,06396162 0,10873003 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 0,06396162 0,10864973 ! negative regulation of protein secretion GO:0050709 20 12 0,000 0,06396162 0,10856954 ! regulation of epidermis development GO:0045682 17 12 0,000 0,06396162 0,10848948 ! intestinal absorption GO:0050892 19 12 0,000 0,06396162 0,10840953 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 0,06396162 0,1083297 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,06396162 0,10824999 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 0,06396162 0,10817039 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,06396162 0,10809091 ! RNA 3'-end processing GO:0031123 20 12 0,000 0,06396162 0,10801155 ! microspike assembly GO:0030035 23 12 0,000 0,06396162 0,1079323 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 0,06396162 0,10785318 ! response to cold GO:0009409 14 12 0,000 0,06396162 0,10777416 ! negative regulation of growth GO:0045926 123 75 1,000 0,0639658 0,10770229 ! response to nutrient GO:0007584 104 75 1,000 0,0639658 0,1076235 ! regulation of cell morphogenesis GO:0022604 140 76 1,000 0,06546633 0,11006765 ! regulation of DNA binding GO:0051101 119 77 1,000 0,06697865 0,11252805 ! regulation of transmission of nerve impulse GO:0051969 116 77 1,000 0,06697865 0,11244592 ! positive regulation of protein complex assembly GO:0031334 19 13 0,000 0,06910528 0,11593154 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,06910528 0,11584704 ! cGMP metabolic process GO:0046068 16 13 0,000 0,06910528 0,11576267 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 17 13 0,000 0,06910528 0,11567841 ! water transport GO:0006833 17 13 0,000 0,06910528 0,11559428 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,06910528 0,11551028 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,06910528 0,11542639 ! lipid localization GO:0010876 24 13 0,000 0,06910528 0,11534263 GO:0019915|lipid storage, ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,06910528 0,11525899 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 0,06910528 0,11517546 ! organelle fusion GO:0048284 28 13 0,000 0,06910528 0,11509206 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,06910528 0,11500879 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! endocrine pancreas development GO:0031018 19 13 0,000 0,06910528 0,11492563 ! cell differentiation in spinal cord GO:0021515 16 13 0,000 0,06910528 0,11484259 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,06910528 0,11475967 ! response to hexose stimulus GO:0009746 19 13 0,000 0,06910528 0,11467687 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! induction of apoptosis via death domain receptors GO:0008625 15 13 0,000 0,06910528 0,11459419 ! glutamate metabolic process GO:0006536 18 13 0,000 0,06910528 0,11451163 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,06910528 0,11442919 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,06910528 0,11434686 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 0,06910528 0,11426466 ! NAD metabolic process GO:0019674 21 13 0,000 0,06910528 0,11418257 ! exocrine system development GO:0035272 27 13 0,000 0,06910528 0,1141006 ! negative regulation of mitotic cell cycle GO:0045930 23 13 0,000 0,06910528 0,11401875 ! bone mineralization GO:0030282 15 13 0,000 0,06910528 0,11393702 ! regulation of exocytosis GO:0017157 17 13 0,000 0,06910528 0,1138554 ! intermediate filament cytoskeleton organization GO:0045104 23 13 0,000 0,06910528 0,1137739 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 0,06910528 0,11369252 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,06910528 0,11361125 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 0,06910528 0,1135301 ! negative regulation of protein import into nucleus GO:0042308 25 13 0,000 0,06910528 0,11344907 ! genitalia development GO:0048806 15 13 0,000 0,06910528 0,11336815 ! regulation of cellular pH GO:0030641 20 13 0,000 0,06910528 0,11328734 ! cellular pigmentation GO:0033059 24 13 0,000 0,06910528 0,11320665 ! tissue regeneration GO:0042246 21 13 0,000 0,06910528 0,11312608 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 0,06910528 0,11304562 ! cofactor transport GO:0051181 19 13 0,000 0,06910528 0,11296527 ! NADP metabolic process GO:0006739 18 13 0,000 0,06910528 0,11288504 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,06910528 0,11280493 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 0,06910528 0,11272492 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,06910528 0,11264503 ! gas transport GO:0015669 18 13 0,000 0,06910528 0,11256526 ! heme biosynthetic process GO:0006783 20 13 0,000 0,06910528 0,11248559 ! regulation of axon extension GO:0030516 23 13 0,000 0,06910528 0,11240604 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 0,000 0,06910528 0,1123266 ! lymphocyte homeostasis GO:0002260 24 13 0,000 0,06910528 0,11224727 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,06910528 0,11216806 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,06910528 0,11208896 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,06910528 0,11200997 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,06910528 0,11193109 ! alcohol catabolic process GO:0046164 104 80 1,000 0,0715847 0,11586545 ! forebrain development GO:0030900 131 80 1,000 0,0715847 0,11578397 ! regulation of cell cycle process GO:0010564 122 81 1,000 0,07314251 0,1182205 ! regulation of neurological system process GO:0031644 122 81 1,000 0,07314251 0,11813748 ! positive regulation of cell activation GO:0050867 120 81 1,000 0,07314251 0,11805457 GO:0002696|positive regulation of leukocyte activation, ! regulation of skeletal muscle tissue development GO:0048641 22 14 0,000 0,07422096 0,11971123 ! G1 phase of mitotic cell cycle GO:0000080 23 14 0,000 0,07422096 0,11962734 ! superoxide anion generation GO:0042554 18 14 0,000 0,07422096 0,11954357 ! neuron maturation GO:0042551 21 14 0,000 0,07422096 0,11945991 ! regulation of lipid biosynthetic process GO:0046890 16 14 0,000 0,07422096 0,11937637 ! myotube differentiation GO:0014902 21 14 0,000 0,07422096 0,11929295 ! heterophilic cell adhesion GO:0007157 29 14 0,000 0,07422096 0,11920965 ! inositol metabolic process GO:0006020 20 14 0,000 0,07422096 0,11912646 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,07422096 0,11904339 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,07422096 0,11896043 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,07422096 0,11887759 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,07422096 0,11879486 ! gene silencing by RNA GO:0031047 20 14 0,000 0,07422096 0,11871225 ! response to cAMP GO:0051591 19 14 0,000 0,07422096 0,11862975 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 0,000 0,07422096 0,11854737 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 0,07422096 0,1184651 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,07422096 0,11838295 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 0,07422096 0,11830091 ! epidermis morphogenesis GO:0048730 29 14 0,000 0,07422096 0,11821899 ! glycine metabolic process GO:0006544 22 14 0,000 0,07422096 0,11813717 ! pituitary gland development GO:0021983 23 14 0,000 0,07422096 0,11805547 ! cellular response to starvation GO:0009267 21 14 0,000 0,07422096 0,11797389 ! lysosomal transport GO:0007041 20 14 0,000 0,07422096 0,11789241 ! regulation of heart rate GO:0002027 23 14 0,000 0,07422096 0,11781105 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,07422096 0,1177298 ! negative regulation of caspase activity GO:0043154 20 14 0,000 0,07422096 0,11764867 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 0,000 0,07422096 0,11756764 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 27 14 0,000 0,07422096 0,11748673 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 0,000 0,07422096 0,11740593 ! G1/S transition checkpoint GO:0031575 33 14 0,000 0,07422096 0,11732523 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 0,07422096 0,11724465 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 24 14 0,000 0,07422096 0,11716418 ! axon cargo transport GO:0008088 27 14 0,000 0,07422096 0,11708382 ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,07422096 0,11700357 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 0,07422096 0,11692344 ! DNA unwinding during replication GO:0006268 21 14 0,000 0,07422096 0,11684341 ! T cell differentiation in the thymus GO:0033077 27 14 0,000 0,07422096 0,11676349 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,07422096 0,11668367 ! mRNA splice site selection GO:0006376 26 14 0,000 0,07422096 0,11660397 ! regulation of T-helper 2 type immune response GO:0002828 21 14 0,000 0,07422096 0,11652438 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,07422096 0,11644489 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 0,07422096 0,11636552 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,07422096 0,11628625 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 0,07422096 0,11620709 ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 0,07422096 0,11612804 ! regulation of erythrocyte differentiation GO:0045646 27 14 0,000 0,07422096 0,11604909 ! muscle maintenance GO:0046716 19 14 0,000 0,07422096 0,11597026 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 0,07422096 0,11589152 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 0,07422096 0,1158129 ! regulation of ATPase activity GO:0043462 18 14 0,000 0,07422096 0,11573438 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,07422096 0,11565597 ! cell killing GO:0001906 20 14 0,000 0,07422096 0,11557767 ! release of cytochrome c from mitochondria GO:0001836 23 14 0,000 0,07422096 0,11549947 ! epithelial to mesenchymal transition GO:0001837 22 14 0,000 0,07422096 0,11542138 ! cilium assembly GO:0042384 20 14 0,000 0,07422096 0,11534339 ! peptide hormone secretion GO:0030072 23 14 0,000 0,07422096 0,11526551 ! biogenic amine metabolic process GO:0006576 121 83 1,000 0,07629081 0,11840005 ! regulation of cell adhesion GO:0030155 159 83 1,000 0,07629081 0,11832021 ! regulation of protein ubiquitination GO:0031396 19 15 0,000 0,07930883 0,12291799 ! positive regulation of cell size GO:0045793 20 15 0,000 0,07930883 0,12283522 ! metencephalon development GO:0022037 19 15 0,000 0,07930883 0,12275256 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,07930883 0,12267001 ! negative regulation of hormone secretion GO:0046888 20 15 0,000 0,07930883 0,12258757 ! negative regulation of cell cycle process GO:0010948 24 15 0,000 0,07930883 0,12250524 ! skin development GO:0043588 25 15 0,000 0,07930883 0,12242302 ! embryonic hindlimb morphogenesis GO:0035116 25 15 0,000 0,07930883 0,12234091 ! embryonic forelimb morphogenesis GO:0035115 17 15 0,000 0,07930883 0,12225891 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 0,000 0,07930883 0,12217703 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 0,07930883 0,12209525 ! bile acid metabolic process GO:0008206 22 15 0,000 0,07930883 0,12201358 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 0,07930883 0,12193202 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 0,07930883 0,12185057 ! adult walking behavior GO:0007628 25 15 0,000 0,07930883 0,12176923 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,07930883 0,12168799 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,07930883 0,12160687 ! myoblast differentiation GO:0045445 27 15 0,000 0,07930883 0,12152585 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,07930883 0,12144494 ! regulation of survival gene product expression GO:0045884 20 15 0,000 0,07930883 0,12136414 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,07930883 0,12128344 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 0,07930883 0,12120286 ! cerebral cortex development GO:0021987 29 15 0,000 0,07930883 0,12112238 ! response to osmotic stress GO:0006970 22 15 0,000 0,07930883 0,121042 ! vesicle coating GO:0006901 25 15 0,000 0,07930883 0,12096174 ! DNA integration GO:0015074 22 15 0,000 0,07930883 0,12088158 ! peptide secretion GO:0002790 27 15 0,000 0,07930883 0,12080152 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,07930883 0,12072158 ! regulation of vasodilation GO:0042312 24 15 0,000 0,07930883 0,12064173 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 0,07930883 0,120562 ! neuron recognition GO:0008038 22 15 0,000 0,07930883 0,12048236 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 0,000 0,07930883 0,12040284 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,07930883 0,12032342 ! positive regulation of oxidoreductase activity GO:0051353 21 15 0,000 0,07930883 0,1202441 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,07930883 0,12016489 ! biomineral formation GO:0031214 18 15 0,000 0,07930883 0,12008578 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,07930883 0,12000678 ! regulation of T-helper cell differentiation GO:0045622 23 15 0,000 0,07930883 0,11992788 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,07930883 0,11984908 ! organic cation transport GO:0015695 19 15 0,000 0,07930883 0,11977039 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,07930883 0,1196918 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 21 15 0,000 0,07930883 0,11961331 ! positive regulation of neuron apoptosis GO:0043525 29 15 0,000 0,07930883 0,11953493 ! defense response to virus GO:0051607 27 15 0,000 0,07930883 0,11945665 ! peptide hormone processing GO:0016486 19 15 0,000 0,07930883 0,11937847 ! negative regulation of multicellular organismal process GO:0051241 133 85 1,000 0,07948162 0,11956032 ! cell cycle arrest GO:0007050 150 86 1,000 0,08109256 0,12190385 ! Wnt receptor signaling pathway GO:0016055 130 87 1,000 0,08271365 0,12425956 ! protein secretion GO:0009306 27 16 0,000 0,08436902 0,12666367 ! hormone secretion GO:0046879 25 16 0,000 0,08436902 0,12658104 ! bone remodeling GO:0046849 24 16 0,000 0,08436902 0,12649853 ! endothelial cell migration GO:0043542 22 16 0,000 0,08436902 0,12641612 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,08436902 0,12633381 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,08436902 0,12625162 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,08436902 0,12616953 ! glial cell development GO:0021782 24 16 0,000 0,08436902 0,12608755 ! patterning of blood vessels GO:0001569 24 16 0,000 0,08436902 0,12600567 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,08436902 0,12592391 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,08436902 0,12584224 ! protein polyubiquitination GO:0000209 26 16 0,000 0,08436902 0,12576069 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,08436902 0,12567924 ! cellular response to unfolded protein GO:0034620 19 16 0,000 0,08436902 0,12559789 GO:0030968|endoplasmic reticulum unfolded protein response, ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 0,08436902 0,12551665 ! fructose metabolic process GO:0006000 20 16 0,000 0,08436902 0,12543551 ! regulation of protein binding GO:0043393 27 16 0,000 0,08436902 0,12535448 ! regulation of dephosphorylation GO:0035303 33 16 0,000 0,08436902 0,12527356 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 0,000 0,08436902 0,12519273 ! protein export from nucleus GO:0006611 24 16 0,000 0,08436902 0,12511202 ! negative regulation of immune response GO:0050777 28 16 0,000 0,08436902 0,1250314 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 0,000 0,08436902 0,12495089 ! DNA replication initiation GO:0006270 25 16 0,000 0,08436902 0,12487049 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,08436902 0,12479019 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 0,000 0,08436902 0,12470999 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,08436902 0,12462989 ! diencephalon development GO:0021536 25 16 0,000 0,08436902 0,1245499 ! neural crest cell migration GO:0001755 24 16 0,000 0,08436902 0,12447001 ! G1 phase GO:0051318 27 16 0,000 0,08436902 0,12439022 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,08436902 0,12431053 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 0,08436902 0,12423095 ! steroid catabolic process GO:0006706 22 16 0,000 0,08436902 0,12415146 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,08436902 0,12407208 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 0,000 0,08436902 0,1239928 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,08436902 0,12391363 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,08436902 0,12383455 ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 0,08436902 0,12375557 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 0,000 0,08436902 0,1236767 ! inner ear receptor cell differentiation GO:0060113 30 16 0,000 0,08436902 0,12359792 ! regulation of neurogenesis GO:0050767 153 89 1,000 0,08598563 0,12588602 ! regulation of T cell activation GO:0050863 128 89 1,000 0,08598563 0,12580594 ! response to virus GO:0009615 122 91 1,000 0,08929632 0,13056677 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,08940168 0,13063779 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,08940168 0,13055484 ! negative regulation of defense response GO:0031348 19 17 0,000 0,08940168 0,130472 ! positive regulation of hormone secretion GO:0046887 24 17 0,000 0,08940168 0,13038927 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,08940168 0,13030664 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,08940168 0,13022411 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,08940168 0,13014169 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,08940168 0,13005938 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 0,000 0,08940168 0,12997716 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,08940168 0,12989506 ! forelimb morphogenesis GO:0035136 19 17 0,000 0,08940168 0,12981305 ! keratinization GO:0031424 17 17 0,000 0,08940168 0,12973115 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,08940168 0,12964935 ! negative regulation of peptidase activity GO:0010466 23 17 0,000 0,08940168 0,12956766 ! retinoid metabolic process GO:0001523 22 17 0,000 0,08940168 0,12948607 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 24 17 0,000 0,08940168 0,12940458 ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,08940168 0,12932319 ! DNA duplex unwinding GO:0032508 25 17 0,000 0,08940168 0,12924191 GO:0032392|DNA geometric change, ! vacuolar transport GO:0007034 24 17 0,000 0,08940168 0,12916073 ! cell-substrate junction assembly GO:0007044 39 17 0,000 0,08940168 0,12907965 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,08940168 0,12899867 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,08940168 0,12891779 ! membrane budding GO:0006900 29 17 0,000 0,08940168 0,12883701 ! heme metabolic process GO:0042168 27 17 0,000 0,08940168 0,12875634 ! actin filament bundle formation GO:0051017 26 17 0,000 0,08940168 0,12867577 ! body fluid secretion GO:0007589 27 17 0,000 0,08940168 0,12859529 ! stem cell differentiation GO:0048863 36 17 0,000 0,08940168 0,12851492 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,08940168 0,12843465 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,08940168 0,12835448 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,08940168 0,12827441 ! sensory perception of pain GO:0019233 23 17 0,000 0,08940168 0,12819444 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,08940168 0,12811456 GO:0002712|regulation of B cell mediated immunity, ! long-chain fatty acid transport GO:0015909 24 17 0,000 0,08940168 0,12803479 ! negative regulation of intracellular transport GO:0032387 29 17 0,000 0,08940168 0,12795512 ! synaptogenesis GO:0007416 24 17 0,000 0,08940168 0,12787554 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,08940168 0,12779607 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,08940168 0,12771669 ! cell-cell junction organization GO:0045216 25 17 0,000 0,08940168 0,12763741 ! regulation of immunoglobulin production GO:0002637 25 17 0,000 0,08940168 0,12755824 ! proximal/distal pattern formation GO:0009954 25 17 0,000 0,08940168 0,12747915 ! aromatic compound catabolic process GO:0019439 22 17 0,000 0,08940168 0,12740017 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,08940168 0,12732128 ! negative regulation of coagulation GO:0050819 23 17 0,000 0,08940168 0,1272425 ! DNA recombination GO:0006310 146 92 1,000 0,0909658 0,12938858 ! regulation of cytoskeleton organization GO:0051493 154 93 1,000 0,0926445 0,1316949 ! carbohydrate catabolic process GO:0016052 121 93 1,000 0,0926445 0,13161356 ! response to oxidative stress GO:0006979 141 94 1,000 0,09433227 0,13392854 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 0,000 0,09440698 0,13395191 ! positive regulation of translation GO:0045727 28 18 0,000 0,09440698 0,13386933 ! positive regulation of anti-apoptosis GO:0045768 29 18 0,000 0,09440698 0,13378684 ! positive regulation of angiogenesis GO:0045766 35 18 0,000 0,09440698 0,13370446 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 0,09440698 0,13362218 ! cAMP metabolic process GO:0046058 33 18 0,000 0,09440698 0,13354001 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,09440698 0,13345793 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,09440698 0,13337595 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 0,09440698 0,13329408 ! axis specification GO:0009798 26 18 0,000 0,09440698 0,1332123 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,09440698 0,13313062 GO:0050886|endocrine process, ! mechanoreceptor differentiation GO:0042490 32 18 0,000 0,09440698 0,13304905 ! pancreas development GO:0031016 26 18 0,000 0,09440698 0,13296757 ! apoptotic mitochondrial changes GO:0008637 29 18 0,000 0,09440698 0,1328862 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,09440698 0,13280492 ! glutamine metabolic process GO:0006541 23 18 0,000 0,09440698 0,13272375 ! response to retinoic acid GO:0032526 25 18 0,000 0,09440698 0,13264267 ! pigmentation during development GO:0048066 31 18 0,000 0,09440698 0,13256169 ! central nervous system neuron development GO:0021954 30 18 0,000 0,09440698 0,13248081 ! positive regulation of cytoskeleton organization GO:0051495 33 18 0,000 0,09440698 0,13240003 ! fucose metabolic process GO:0006004 26 18 0,000 0,09440698 0,13231935 ! response to fungus GO:0009620 19 18 0,000 0,09440698 0,13223876 ! peptide cross-linking GO:0018149 31 18 0,000 0,09440698 0,13215828 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 0,000 0,09440698 0,13207789 ! heart process GO:0003015 27 18 0,000 0,09440698 0,1319976 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,09440698 0,1319174 GO:0006692|prostanoid metabolic process, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,09440698 0,13183731 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,09440698 0,13175731 ! detection of chemical stimulus GO:0009593 26 18 0,000 0,09440698 0,13167741 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,09440698 0,1315976 ! cellular response to nutrient levels GO:0031669 27 18 0,000 0,09440698 0,1315179 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,09440698 0,13143829 ! vitamin transport GO:0051180 24 18 0,000 0,09440698 0,13135877 ! hormone transport GO:0009914 27 18 0,000 0,09440698 0,13127935 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,09440698 0,13120003 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,09440698 0,1311208 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,09440698 0,13104167 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,09440698 0,13096263 ! estrogen receptor signaling pathway GO:0030520 30 18 0,000 0,09440698 0,13088369 ! gut development GO:0048565 26 18 0,000 0,09440698 0,13080485 ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 0,000 0,09440698 0,1307261 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 0,000 0,09440698 0,13064744 ! regulation of binding GO:0051098 151 95 1,000 0,09602898 0,13281217 ! carboxylic acid transport GO:0046942 147 95 1,000 0,09602898 0,13273236 GO:0015849|organic acid transport, ! in utero embryonic development GO:0001701 147 96 1,000 0,09773446 0,13500856 ! regulation of cellular component biogenesis GO:0044087 158 96 1,000 0,09773446 0,13492752 ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,09938504 0,13712393 ! positive regulation of protein catabolic process GO:0045732 23 19 0,000 0,09938504 0,13704173 ! positive regulation of ossification GO:0045778 30 19 0,000 0,09938504 0,13695962 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,09938504 0,1368776 ! reciprocal meiotic recombination GO:0007131 31 19 0,000 0,09938504 0,13679569 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 0,000 0,09938504 0,13671387 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,09938504 0,13663216 ! regeneration GO:0031099 32 19 0,000 0,09938504 0,13655054 ! response to alkaloid GO:0043279 32 19 0,000 0,09938504 0,13646901 ! sensory perception of taste GO:0050909 23 19 0,000 0,09938504 0,13638759 ! smooth muscle contraction GO:0006939 36 19 0,000 0,09938504 0,13630626 ! peroxisome organization GO:0007031 29 19 0,000 0,09938504 0,13622503 ! digestive system process GO:0022600 30 19 0,000 0,09938504 0,13614389 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,09938504 0,13606286 ! response to vitamin A GO:0033189 26 19 0,000 0,09938504 0,13598191 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,09938504 0,13590107 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,09938504 0,13582032 ! cell structure disassembly during apoptosis GO:0006921 24 19 0,000 0,09938504 0,13573967 ! apoptotic nuclear changes GO:0030262 24 19 0,000 0,09938504 0,13565911 ! response to starvation GO:0042594 30 19 0,000 0,09938504 0,13557865 ! response to lipopolysaccharide GO:0032496 26 19 0,000 0,09938504 0,13549828 ! plasma membrane fusion GO:0045026 23 19 0,000 0,09938504 0,13541801 ! cytolysis GO:0019835 20 19 0,000 0,09938504 0,13533783 ! renal system process GO:0003014 35 19 0,000 0,09938504 0,13525775 ! vasodilation GO:0042311 33 19 0,000 0,09938504 0,13517776 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,09938504 0,13509787 ! regulation of fatty acid metabolic process GO:0019217 28 19 0,000 0,09938504 0,13501807 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,09938504 0,13493837 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,09938504 0,13485876 ! negative regulation of angiogenesis GO:0016525 36 19 0,000 0,09938504 0,13477924 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,09938504 0,13469982 ! sarcomere organization GO:0045214 23 19 0,000 0,09938504 0,13462049 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 0,000 0,09938504 0,13454126 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,09938504 0,13446212 ! aromatic amino acid family metabolic process GO:0009072 24 19 0,000 0,09938504 0,13438307 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,09938504 0,13430411 GO:0043450|alkene biosynthetic process, ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 0,09938504 0,13422525 ! embryonic organ morphogenesis GO:0048562 23 19 0,000 0,09938504 0,13414648 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 0,09938504 0,1340678 ! protein stabilization GO:0050821 26 19 0,000 0,09938504 0,13398921 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 1,000 0,09944857 0,13399632 ! calcium ion transport GO:0006816 167 99 1,000 0,10290214 0,13856845 ! extracellular structure organization GO:0043062 156 99 1,000 0,10290214 0,13848737 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,10433603 0,14033501 ! iron ion transport GO:0006826 37 20 0,000 0,10433603 0,14025299 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,10433603 0,14017106 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,10433603 0,14008924 GO:0006044|N-acetylglucosamine metabolic process, ! response to vitamin GO:0033273 29 20 0,000 0,10433603 0,1400075 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,10433603 0,13992587 ! hindlimb morphogenesis GO:0035137 32 20 0,000 0,10433603 0,13984432 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,10433603 0,13976288 ! spinal cord development GO:0021510 31 20 0,000 0,10433603 0,13968153 ! multicellular organismal response to stress GO:0033555 32 20 0,000 0,10433603 0,13960027 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,10433603 0,13951911 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,10433603 0,13943804 ! chromosome condensation GO:0030261 31 20 0,000 0,10433603 0,13935706 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,10433603 0,13927618 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 0,000 0,10433603 0,1391954 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,10433603 0,1391147 ! regulation of ARF GTPase activity GO:0032312 31 20 0,000 0,10433603 0,1390341 ! DNA modification GO:0006304 28 20 0,000 0,10433603 0,1389536 ! collagen fibril organization GO:0030199 45 20 0,000 0,10433603 0,13887318 ! positive regulation of osteoblast differentiation GO:0045669 33 20 0,000 0,10433603 0,13879286 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,10433603 0,13871264 ! collagen catabolic process GO:0030574 25 20 0,000 0,10433603 0,1386325 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,10433603 0,13855246 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 0,10433603 0,13847251 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,10433603 0,13839265 ! actin filament-based movement GO:0030048 34 20 0,000 0,10433603 0,13831289 ! regulation of translation GO:0006417 151 100 1,000 0,1046413 0,13863766 ! divalent metal ion transport GO:0070838 171 100 1,000 0,1046413 0,13855785 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 0,000 0,10926008 0,14459043 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 0,000 0,10926008 0,14450729 GO:0016444|somatic cell DNA recombination, ! regulation of cell killing GO:0031341 34 21 0,000 0,10926008 0,14442424 ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 0,10926008 0,14434128 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,10926008 0,14425842 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,10926008 0,14417566 GO:0009799|determination of symmetry, ! DNA catabolic process, endonucleolytic GO:0000737 26 21 0,000 0,10926008 0,14409299 ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,10926008 0,14401041 GO:0034105|positive regulation of tissue remodeling, ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,10926008 0,14392793 ! phototransduction GO:0007602 25 21 0,000 0,10926008 0,14384555 ! regulation of DNA recombination GO:0000018 40 21 0,000 0,10926008 0,14376326 ! ovarian follicle development GO:0001541 30 21 0,000 0,10926008 0,14368106 ! activation of pro-apoptotic gene products GO:0008633 36 21 0,000 0,10926008 0,14359896 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,10926008 0,14351695 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,10926008 0,14343503 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,10926008 0,14335321 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 0,000 0,10926008 0,14327148 ! regulation of insulin secretion GO:0050796 26 21 0,000 0,10926008 0,14318984 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 0,000 0,10926008 0,1431083 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 0,000 0,10926008 0,14302685 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 0,10926008 0,14294549 GO:0060415|muscle tissue morphogenesis, ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,10926008 0,14286423 ! leukotriene metabolic process GO:0006691 28 21 0,000 0,10926008 0,14278305 ! regulation of vasoconstriction GO:0019229 31 21 0,000 0,10926008 0,14270197 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,10926008 0,14262098 ! fatty acid transport GO:0015908 30 21 0,000 0,10926008 0,14254009 ! immunoglobulin production GO:0002377 33 21 0,000 0,10926008 0,14245928 GO:0002440|production of molecular mediator of immune response, ! platelet activation GO:0030168 28 21 0,000 0,10926008 0,14237857 ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 0,000 0,10926008 0,14229795 ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,10926008 0,14221742 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,10926008 0,14213698 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,10926008 0,14205663 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,10926008 0,14197637 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,10926008 0,1418962 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,10926008 0,14181613 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,10926008 0,14173614 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,10926008 0,14165624 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,10926008 0,14157644 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,10926008 0,14149672 ! acetyl-CoA catabolic process GO:0046356 31 21 0,000 0,10926008 0,14141709 GO:0006099|tricarboxylic acid cycle, ! regulation of multi-organism process GO:0043900 32 21 0,000 0,10926008 0,14133756 ! protein import into nucleus, translocation GO:0000060 36 22 0,000 0,11415733 0,14758958 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 0,000 0,11415733 0,14750667 ! regulation of anti-apoptosis GO:0045767 36 22 0,000 0,11415733 0,14742385 ! viral genome replication GO:0019079 29 22 0,000 0,11415733 0,14734112 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,11415733 0,14725848 ! leukocyte adhesion GO:0007159 38 22 0,000 0,11415733 0,14717594 ! molting cycle process GO:0022404 40 22 0,000 0,11415733 0,14709348 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! dicarboxylic acid metabolic process GO:0043648 33 22 0,000 0,11415733 0,14701112 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,11415733 0,14692886 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 0,000 0,11415733 0,14684668 ! regulation of cell-matrix adhesion GO:0001952 51 22 0,000 0,11415733 0,1467646 GO:0010810|regulation of cell-substrate adhesion, ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 0,000 0,11415733 0,14668261 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of smooth muscle contraction GO:0006940 36 22 0,000 0,11415733 0,14660071 ! lysosome organization GO:0007040 37 22 0,000 0,11415733 0,1465189 ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,11415733 0,14643718 GO:0051693|actin filament capping, ! ureteric bud development GO:0001657 32 22 0,000 0,11415733 0,14635556 ! coenzyme catabolic process GO:0009109 33 22 0,000 0,11415733 0,14627402 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,11415733 0,14619258 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,11415733 0,14611122 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,11415733 0,14602996 ! leukocyte homeostasis GO:0001776 33 22 0,000 0,11415733 0,14594879 ! regulation of blood coagulation GO:0030193 34 22 0,000 0,11415733 0,1458677 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,11415733 0,14578671 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,11415733 0,14570581 ! neural tube closure GO:0001843 33 22 0,000 0,11415733 0,145625 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,11415733 0,14554427 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 0,000 0,11902795 0,15166996 ! neuron fate commitment GO:0048663 32 23 0,000 0,11902795 0,15158598 ! embryonic pattern specification GO:0009880 31 23 0,000 0,11902795 0,15150209 ! acetyl-CoA metabolic process GO:0006084 33 23 0,000 0,11902795 0,1514183 ! cellular iron ion homeostasis GO:0006879 37 23 0,000 0,11902795 0,15133459 ! vesicle targeting GO:0006903 32 23 0,000 0,11902795 0,15125098 ! response to corticosteroid stimulus GO:0031960 36 23 0,000 0,11902795 0,15116746 ! osteoblast differentiation GO:0001649 40 23 0,000 0,11902795 0,15108404 ! regulation of viral reproduction GO:0050792 32 23 0,000 0,11902795 0,1510007 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,11902795 0,15091746 ! lymphocyte proliferation GO:0046651 36 23 0,000 0,11902795 0,15083431 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,11902795 0,15075125 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,11902795 0,15066829 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,11902795 0,15058541 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,11902795 0,15050263 ! cell fate determination GO:0001709 45 23 0,000 0,11902795 0,15041993 ! pentose metabolic process GO:0019321 31 23 0,000 0,11902795 0,15033733 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,11902795 0,15025482 ! spermatid development GO:0007286 33 23 0,000 0,11902795 0,1501724 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,11902795 0,15009006 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,11902795 0,15000782 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,11902795 0,14992567 ! somatic diversification of immune receptors GO:0002200 35 23 0,000 0,11902795 0,14984361 ! telomere organization GO:0032200 32 23 0,000 0,11902795 0,14976164 GO:0000723|telomere maintenance, ! response to molecule of bacterial origin GO:0002237 30 23 0,000 0,11902795 0,14967976 ! regulation of amine transport GO:0051952 38 23 0,000 0,11902795 0,14959797 ! liver development GO:0001889 40 23 0,000 0,11902795 0,14951626 ! initiation of viral infection GO:0019059 42 24 0,000 0,12387206 0,15551623 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,12387206 0,15543139 ! superoxide metabolic process GO:0006801 32 24 0,000 0,12387206 0,15534664 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,12387206 0,15526198 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! fat cell differentiation GO:0045444 37 24 0,000 0,12387206 0,15517741 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,12387206 0,15509294 ! sperm motility GO:0030317 27 24 0,000 0,12387206 0,15500856 ! mitochondrial membrane organization GO:0007006 39 24 0,000 0,12387206 0,15492427 ! vacuole organization GO:0007033 39 24 0,000 0,12387206 0,15484007 ! receptor metabolic process GO:0043112 37 24 0,000 0,12387206 0,15475596 ! neural crest cell development GO:0014032 39 24 0,000 0,12387206 0,15467195 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 38 24 0,000 0,12387206 0,15458803 ! primary neural tube formation GO:0014020 35 24 0,000 0,12387206 0,15450419 ! regulation of alpha-beta T cell activation GO:0046634 35 24 0,000 0,12387206 0,15442045 ! base-excision repair GO:0006284 31 24 0,000 0,12387206 0,1543368 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,12387206 0,15425324 GO:0002708|positive regulation of lymphocyte mediated immunity, ! glutathione metabolic process GO:0006749 29 24 0,000 0,12387206 0,15416977 ! regulation of osteoblast differentiation GO:0045667 37 24 0,000 0,12387206 0,15408639 ! neurotransmitter secretion GO:0007269 32 24 0,000 0,12387206 0,1540031 ! regulation of JUN kinase activity GO:0043506 34 24 0,000 0,12387206 0,1539199 ! negative regulation of actin filament depolymerization GO:0030835 36 25 0,000 0,12868981 0,15981995 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,12868981 0,15973371 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,12868981 0,15964755 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,12868981 0,15956149 GO:0006479|protein amino acid methylation, ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,12868981 0,15947552 ! regulation of cellular ketone metabolic process GO:0010565 34 25 0,000 0,12868981 0,15938964 ! peptide transport GO:0015833 43 25 0,000 0,12868981 0,15930385 ! male gonad development GO:0008584 33 25 0,000 0,12868981 0,15921816 ! iron ion homeostasis GO:0055072 39 25 0,000 0,12868981 0,15913256 ! regulation of peptide secretion GO:0002791 34 25 0,000 0,12868981 0,15904705 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,12868981 0,15896163 ! regulation of chromosome organization GO:0033044 35 25 0,000 0,12868981 0,15887631 ! phospholipid transport GO:0015914 35 25 0,000 0,12868981 0,15879107 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,12868981 0,15870593 ! positive regulation of MAPKKK cascade GO:0043410 36 25 0,000 0,12868981 0,15862088 ! detection of light stimulus GO:0009583 30 25 0,000 0,12868981 0,15853592 ! positive regulation of nuclear division GO:0051785 39 25 0,000 0,12868981 0,15845105 GO:0045840|positive regulation of mitosis, ! leukocyte proliferation GO:0070661 39 25 0,000 0,12868981 0,15836627 GO:0032943|mononuclear cell proliferation, ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,13348134 0,16417491 ! translational initiation GO:0006413 43 26 0,000 0,13348134 0,16408716 ! regulation of pH GO:0006885 36 26 0,000 0,13348134 0,16399951 ! circadian rhythm GO:0007623 42 26 0,000 0,13348134 0,16391195 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,13348134 0,16382448 ! post-embryonic development GO:0009791 42 26 0,000 0,13348134 0,16373711 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,13348134 0,16364983 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,13348134 0,16356264 ! negative regulation of protein kinase cascade GO:0010741 51 26 0,000 0,13348134 0,16347555 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,13348134 0,16338855 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,13348134 0,16330164 ! negative regulation of protein polymerization GO:0032272 38 26 0,000 0,13348134 0,16321482 ! regulation of coagulation GO:0050818 39 26 0,000 0,13348134 0,1631281 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,13824679 0,16886226 ! regulation of actin filament depolymerization GO:0030834 39 27 0,000 0,13824679 0,16877263 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,13824679 0,16868309 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,13824679 0,16859365 ! inner ear morphogenesis GO:0042472 35 27 0,000 0,13824679 0,16850431 ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,13824679 0,16841506 ! acute-phase response GO:0006953 42 27 0,000 0,13824679 0,1683259 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,13824679 0,16823684 ! myofibril assembly GO:0030239 36 27 0,000 0,13824679 0,16814787 GO:0055002|striated muscle cell development, ! respiratory gaseous exchange GO:0007585 47 27 0,000 0,13824679 0,168059 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 0,000 0,13824679 0,16797022 ! natural killer cell activation GO:0030101 35 27 0,000 0,13824679 0,16788154 ! lipid oxidation GO:0034440 38 27 0,000 0,13824679 0,16779294 GO:0019395|fatty acid oxidation, ! cofactor catabolic process GO:0051187 45 27 0,000 0,13824679 0,16770445 ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,13824679 0,16761604 ! negative regulation of transcription regulator activity GO:0090048 47 27 0,000 0,13824679 0,16752773 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of neuron apoptosis GO:0043524 42 27 0,000 0,13824679 0,16743951 ! negative regulation of protein transport GO:0051224 49 27 0,000 0,13824679 0,16735138 ! gene silencing GO:0016458 41 27 0,000 0,13824679 0,16726335 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 0,000 0,14298631 0,17290669 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,14298631 0,17281583 ! negative regulation of protein complex assembly GO:0031333 42 28 0,000 0,14298631 0,17272506 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,14298631 0,17263439 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,14298631 0,17254382 ! cell junction assembly GO:0034329 56 28 0,000 0,14298631 0,17245334 ! positive regulation of endocytosis GO:0045807 33 28 0,000 0,14298631 0,17236296 ! cholesterol homeostasis GO:0042632 46 28 0,000 0,14298631 0,17227267 GO:0055092|sterol homeostasis, ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,14298631 0,17218247 ! complement activation, classical pathway GO:0006958 36 28 0,000 0,14298631 0,17209237 ! triglyceride metabolic process GO:0006641 34 28 0,000 0,14298631 0,17200237 ! erythrocyte differentiation GO:0030218 38 28 0,000 0,14298631 0,17191245 ! immune response-activating signal transduction GO:0002757 38 28 0,000 0,14298631 0,17182263 GO:0002764|immune response-regulating signal transduction, ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,14298631 0,17173291 ! positive regulation of T cell differentiation GO:0045582 39 28 0,000 0,14298631 0,17164328 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,14298631 0,17155374 ! mesoderm formation GO:0001707 46 28 0,000 0,14298631 0,1714643 ! positive regulation of multicellular organism growth GO:0040018 38 28 0,000 0,14298631 0,17137495 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,14298631 0,17128569 ! BMP signaling pathway GO:0030509 40 28 0,000 0,14298631 0,17119652 ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,14298631 0,17110745 ! myeloid leukocyte activation GO:0002274 39 28 0,000 0,14298631 0,17101847 ! neural tube formation GO:0001841 41 28 0,000 0,14298631 0,17092959 ! placenta development GO:0001890 37 28 0,000 0,14298631 0,17084079 ! response to hydrogen peroxide GO:0042542 42 29 0,000 0,14770004 0,17638114 ! regulation of innate immune response GO:0045088 38 29 0,000 0,14770004 0,17628961 ! ovulation cycle process GO:0022602 41 29 0,000 0,14770004 0,17619818 ! positive regulation of T cell proliferation GO:0042102 44 29 0,000 0,14770004 0,17610683 ! protein targeting to membrane GO:0006612 53 29 0,000 0,14770004 0,17601559 ! regulation of axonogenesis GO:0050770 51 29 0,000 0,14770004 0,17592444 ! mismatch repair GO:0006298 34 29 0,000 0,14770004 0,17583338 ! muscle cell development GO:0055001 38 29 0,000 0,14770004 0,17574241 ! formation of primary germ layer GO:0001704 48 29 0,000 0,14770004 0,17565154 ! eye morphogenesis GO:0048592 51 29 0,000 0,14770004 0,17556077 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,14770004 0,17547008 ! tissue homeostasis GO:0001894 42 29 0,000 0,14770004 0,1753795 GO:0048871|multicellular organismal homeostasis, ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 0,000 0,1523881 0,18085275 ! collagen metabolic process GO:0032963 40 30 0,000 0,1523881 0,18075948 ! organic anion transport GO:0015711 51 30 0,000 0,1523881 0,18066631 ! cholesterol transport GO:0030301 46 30 0,000 0,1523881 0,18057323 GO:0015918|sterol transport, ! spliceosome assembly GO:0000245 49 30 0,000 0,1523881 0,18048024 ! spindle organization GO:0007051 37 30 0,000 0,1523881 0,18038736 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,1523881 0,18029456 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,1523881 0,18020187 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,1523881 0,18010927 ! ceramide metabolic process GO:0006672 43 30 0,000 0,1523881 0,18001676 ! ovulation cycle GO:0042698 43 30 0,000 0,1523881 0,17992435 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,1523881 0,17983203 ! adult locomotory behavior GO:0008344 47 30 0,000 0,1523881 0,17973981 ! embryonic epithelial tube formation GO:0001838 44 30 0,000 0,1523881 0,17964769 ! response to heat GO:0009408 41 30 0,000 0,1523881 0,17955565 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,1523881 0,17946371 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,1523881 0,17937187 ! DNA damage checkpoint GO:0000077 53 31 0,000 0,15705065 0,18476547 ! negative regulation of secretion GO:0051048 49 31 0,000 0,15705065 0,18467101 ! glial cell differentiation GO:0010001 55 31 0,000 0,15705065 0,18457664 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 0,000 0,15705065 0,18448237 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,15705065 0,1843882 ! xenobiotic metabolic process GO:0006805 44 31 0,000 0,15705065 0,18429413 ! odontogenesis GO:0042476 50 31 0,000 0,15705065 0,18420015 ! maintenance of protein location in cell GO:0032507 60 31 0,000 0,15705065 0,18410626 ! regulation of striated muscle tissue development GO:0016202 47 31 0,000 0,15705065 0,18401247 ! mesoderm morphogenesis GO:0048332 49 31 0,000 0,15705065 0,18391878 ! metanephros development GO:0001656 58 31 0,000 0,15705065 0,18382518 ! positive regulation of gene-specific transcription GO:0043193 47 31 0,000 0,15705065 0,18373168 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,15705065 0,18363828 ! response to mechanical stimulus GO:0009612 43 31 0,000 0,15705065 0,18354496 ! cell fate specification GO:0001708 37 31 0,000 0,15705065 0,18345175 ! biogenic amine biosynthetic process GO:0042401 44 31 0,000 0,15705065 0,18335862 ! RNA modification GO:0009451 40 31 0,000 0,15705065 0,1832656 ! regulation of muscle development GO:0048634 48 32 0,000 0,16168781 0,18858112 ! mitotic sister chromatid segregation GO:0000070 45 32 0,000 0,16168781 0,18848554 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 0,000 0,16168781 0,18839005 ! meiosis I GO:0007127 52 32 0,000 0,16168781 0,18829467 ! regulation of ARF protein signal transduction GO:0032012 51 32 0,000 0,16168781 0,18819937 ! neutral lipid metabolic process GO:0006638 41 32 0,000 0,16168781 0,18810418 GO:0006639|acylglycerol metabolic process, ! monovalent inorganic cation homeostasis GO:0055067 45 32 0,000 0,16168781 0,18800908 ! regulation of protein stability GO:0031647 48 32 0,000 0,16168781 0,18791408 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 0,000 0,16168781 0,18781917 ! cytokine production GO:0001816 44 32 0,000 0,16168781 0,18772436 ! vesicle localization GO:0051648 47 32 0,000 0,16168781 0,18762965 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 0,000 0,16629973 0,1928842 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! RNA export from nucleus GO:0006405 44 33 0,000 0,16629973 0,19278698 ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,16629973 0,19268986 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,16629973 0,19259284 ! negative regulation of cell adhesion GO:0007162 67 33 0,000 0,16629973 0,19249591 ! sister chromatid segregation GO:0000819 46 33 0,000 0,16629973 0,19239908 ! ear morphogenesis GO:0042471 42 33 0,000 0,16629973 0,19230235 ! actomyosin structure organization GO:0031032 43 33 0,000 0,16629973 0,19220572 ! cell junction organization GO:0034330 63 33 0,000 0,16629973 0,19210918 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,16629973 0,19201274 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,16629973 0,19191639 ! nucleus organization GO:0006997 49 33 0,000 0,16629973 0,19182015 ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 0,000 0,16629973 0,191724 ! negative regulation of DNA binding GO:0043392 54 33 0,000 0,16629973 0,19162794 ! positive regulation of cell development GO:0010720 54 33 0,000 0,16629973 0,19153199 ! lipid homeostasis GO:0055088 55 33 0,000 0,16629973 0,19143612 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,16629973 0,19134036 ! regulation of proteolysis GO:0030162 50 33 0,000 0,16629973 0,19124469 ! negative regulation of hydrolase activity GO:0051346 50 33 0,000 0,16629973 0,19114911 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,16629973 0,19105363 ! androgen receptor signaling pathway GO:0030521 54 33 0,000 0,16629973 0,19095825 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,16629973 0,19086296 ! mRNA catabolic process GO:0006402 48 34 0,000 0,17088654 0,19602944 ! regulation of neuron projection development GO:0010975 63 34 0,000 0,17088654 0,19593172 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 0,000 0,17088654 0,1958341 ! establishment or maintenance of cell polarity GO:0007163 61 34 0,000 0,17088654 0,19573657 ! feeding behavior GO:0007631 45 34 0,000 0,17088654 0,19563914 ! mitotic cell cycle checkpoint GO:0007093 63 34 0,000 0,17088654 0,19554181 ! development of primary male sexual characteristics GO:0046546 44 34 0,000 0,17088654 0,19544457 ! DNA integrity checkpoint GO:0031570 57 34 0,000 0,17088654 0,19534743 ! glycerol ether metabolic process GO:0006662 44 34 0,000 0,17088654 0,19525039 ! erythrocyte homeostasis GO:0034101 45 34 0,000 0,17088654 0,19515344 ! neuron migration GO:0001764 46 34 0,000 0,17088654 0,19505659 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 0,000 0,17088654 0,19495984 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,17088654 0,19486318 ! aerobic respiration GO:0009060 47 34 0,000 0,17088654 0,19476662 ! embryonic organ development GO:0048568 45 34 0,000 0,17088654 0,19467015 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 0,000 0,17088654 0,19457378 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,17544837 0,1996691 ! Notch signaling pathway GO:0007219 56 35 0,000 0,17544837 0,19957035 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,17544837 0,1994717 GO:0032313|regulation of Rab GTPase activity, ! keratinocyte differentiation GO:0030216 47 35 0,000 0,17544837 0,19937315 ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,17544837 0,19927469 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,17544837 0,19917634 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 65 35 0,000 0,17544837 0,19907807 ! Rho protein signal transduction GO:0007266 51 35 0,000 0,17544837 0,19897991 ! pigment metabolic process GO:0042440 61 35 0,000 0,17544837 0,19888184 ! regulation of hormone secretion GO:0046883 48 36 0,000 0,17998537 0,20392431 ! cellular amide metabolic process GO:0043603 52 36 0,000 0,17998537 0,2038239 ! negative regulation of binding GO:0051100 58 36 0,000 0,17998537 0,20372359 ! organic ether metabolic process GO:0018904 46 36 0,000 0,17998537 0,20362339 ! neural tube development GO:0021915 50 36 0,000 0,17998537 0,20352328 ! hormone-mediated signaling GO:0009755 49 36 0,000 0,17998537 0,20342327 ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,17998537 0,20332335 ! response to xenobiotic stimulus GO:0009410 50 36 0,000 0,17998537 0,20322354 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 0,000 0,18449766 0,2082162 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,18449766 0,20811408 GO:0006956|complement activation, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,18449766 0,20801206 ! ion transmembrane transport GO:0034220 56 37 0,000 0,18449766 0,20791015 ! ribonucleoside metabolic process GO:0009119 48 37 0,000 0,18449766 0,20780833 ! regulation of protein secretion GO:0050708 51 37 0,000 0,18449766 0,20770661 ! amino acid activation GO:0043038 52 37 0,000 0,18449766 0,207605 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,18449766 0,20750348 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 0,000 0,18898537 0,2124469 ! gliogenesis GO:0042063 71 38 0,000 0,18898537 0,21234312 ! striated muscle cell differentiation GO:0051146 54 38 0,000 0,18898537 0,21223943 ! monocarboxylic acid transport GO:0015718 62 38 0,000 0,18898537 0,21213585 ! phagocytosis GO:0006909 60 38 0,000 0,18898537 0,21203237 ! mesenchymal cell development GO:0014031 64 38 0,000 0,18898537 0,21192899 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! pigmentation GO:0043473 74 38 0,000 0,18898537 0,21182571 ! maintenance of location in cell GO:0051651 69 38 0,000 0,18898537 0,21172253 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 0,000 0,19344865 0,21661728 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,19344865 0,21651187 ! morphogenesis of embryonic epithelium GO:0016331 60 39 0,000 0,19344865 0,21640656 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 0,000 0,19344865 0,21630136 ! multicellular organismal metabolic process GO:0044236 50 39 0,000 0,19344865 0,21619626 ! male sex differentiation GO:0046661 53 39 0,000 0,19344865 0,21609126 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 0,000 0,19344865 0,21598636 ! chromatin remodeling GO:0006338 68 39 0,000 0,19344865 0,21588156 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,19344865 0,21577687 ! JNK cascade GO:0007254 54 39 0,000 0,19344865 0,21567227 ! cell growth GO:0016049 61 39 0,000 0,19344865 0,21556778 ! regulation of actin filament polymerization GO:0030833 59 40 0,000 0,19788762 0,22040752 ! response to calcium ion GO:0051592 58 40 0,000 0,19788762 0,22030083 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 0,000 0,19788762 0,22019425 ! regulation of tube size GO:0035150 60 40 0,000 0,19788762 0,22008778 GO:0050880|regulation of blood vessel size, ! detection of stimulus involved in sensory perception GO:0050906 50 40 0,000 0,19788762 0,2199814 ! peptide metabolic process GO:0006518 56 40 0,000 0,19788762 0,21987513 ! inner ear development GO:0048839 57 40 0,000 0,19788762 0,21976896 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,19788762 0,2196629 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! T cell differentiation GO:0030217 65 40 0,000 0,19788762 0,21955693 ! B cell differentiation GO:0030183 62 40 0,000 0,19788762 0,21945107 ! epidermal cell differentiation GO:0009913 53 40 0,000 0,19788762 0,21934531 ! regulation of myeloid cell differentiation GO:0045637 69 40 0,000 0,19788762 0,21923966 ! JAK-STAT cascade GO:0007259 53 40 0,000 0,19788762 0,2191341 ! epithelial cell differentiation GO:0030855 55 41 0,000 0,20230241 0,22391508 ! protein amino acid lipidation GO:0006497 62 41 0,000 0,20230241 0,22380738 ! striated muscle contraction GO:0006941 62 41 0,000 0,20230241 0,22369978 ! regulation of leukocyte mediated immunity GO:0002703 62 41 0,000 0,20230241 0,22359228 ! biopolymer methylation GO:0043414 62 41 0,000 0,20230241 0,22348489 ! regulation of JNK cascade GO:0046328 58 41 0,000 0,20230241 0,2233776 ! mitochondrial transport GO:0006839 60 42 0,000 0,20669315 0,22811625 ! receptor-mediated endocytosis GO:0006898 76 42 0,000 0,20669315 0,22800684 ! regulation of JAK-STAT cascade GO:0046425 61 42 0,000 0,20669315 0,22789753 ! cellular component disassembly GO:0022411 64 42 0,000 0,20669315 0,22778834 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 0,000 0,20669315 0,22767924 ! branching morphogenesis of a tube GO:0048754 72 42 0,000 0,20669315 0,22757025 ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,20669315 0,22746137 ! excretion GO:0007588 63 42 0,000 0,20669315 0,22735259 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,20669315 0,22724391 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,20669315 0,22713533 ! activation of caspase activity GO:0006919 65 43 0,000 0,21105998 0,23182328 ! tRNA processing GO:0008033 49 43 0,000 0,21105998 0,23171263 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 0,000 0,21105998 0,23160208 ! vesicle organization GO:0016050 79 43 0,000 0,21105998 0,23149163 ! epithelial tube morphogenesis GO:0060562 65 43 0,000 0,21105998 0,2313813 ! methylation GO:0032259 64 43 0,000 0,21105998 0,23127106 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,21540302 0,23591759 ! glycolysis GO:0006096 53 44 0,000 0,21540302 0,2358053 ! regulation of ion transport GO:0043269 57 44 0,000 0,21540302 0,23569312 ! cellular amino acid biosynthetic process GO:0008652 51 44 0,000 0,21540302 0,23558105 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 0,000 0,21540302 0,23546908 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,21540302 0,23535722 ! detection of abiotic stimulus GO:0009582 58 44 0,000 0,21540302 0,23524546 ! RNA catabolic process GO:0006401 64 45 0,000 0,2197224 0,23984884 ! regulation of translational initiation GO:0006446 64 45 0,000 0,2197224 0,23973506 ! lipoprotein biosynthetic process GO:0042158 67 45 0,000 0,2197224 0,23962139 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,22401824 0,2441905 ! cell redox homeostasis GO:0045454 63 46 0,000 0,22401824 0,24407483 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,22401824 0,24395926 ! regulation of ossification GO:0030278 71 46 0,000 0,22401824 0,2438438 ! regulation of adaptive immune response GO:0002819 72 46 0,000 0,22401824 0,24372846 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,22829068 0,24825937 ! viral infectious cycle GO:0019058 71 47 0,000 0,22829068 0,24814205 ! endocrine system development GO:0035270 83 47 0,000 0,22829068 0,24802483 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 0,000 0,22829068 0,24790773 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,22829068 0,24779074 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,22829068 0,24767385 ! regulation of neuron apoptosis GO:0043523 77 47 0,000 0,22829068 0,24755708 ! regulation of protein polymerization GO:0032271 71 47 0,000 0,22829068 0,24744042 ! chloride transport GO:0006821 67 48 0,000 0,23253984 0,25192729 ! positive regulation of caspase activity GO:0043280 72 48 0,000 0,23253984 0,25180868 GO:0010952|positive regulation of peptidase activity, ! response to temperature stimulus GO:0009266 62 48 0,000 0,23253984 0,25169018 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 0,000 0,23253984 0,25157179 ! gastrulation GO:0007369 73 48 0,000 0,23253984 0,25145352 ! immunoglobulin mediated immune response GO:0016064 66 48 0,000 0,23253984 0,25133535 GO:0019724|B cell mediated immunity, ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 0,000 0,23253984 0,2512173 ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,23253984 0,25109936 ! regulation of endocytosis GO:0030100 63 48 0,000 0,23253984 0,25098153 ! nuclear export GO:0051168 69 48 0,000 0,23253984 0,25086381 ! positive regulation of cytokine production GO:0001819 73 48 0,000 0,23253984 0,2507462 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,23676585 0,25518343 ! sensory perception of smell GO:0007608 61 49 0,000 0,23676585 0,25506391 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,23676585 0,2549445 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,23676585 0,2548252 ! RNA elongation GO:0006354 62 49 0,000 0,23676585 0,25470601 ! morphogenesis of a branching structure GO:0001763 86 49 0,000 0,23676585 0,25458693 ! heterocycle catabolic process GO:0046700 72 49 0,000 0,23676585 0,25446797 ! maintenance of location GO:0051235 84 49 0,000 0,23676585 0,25434911 ! regulation of actin filament length GO:0030832 72 50 0,000 0,24096882 0,25874337 ! ear development GO:0043583 72 50 0,000 0,24096882 0,25862263 ! membrane fusion GO:0006944 80 50 0,000 0,24096882 0,258502 ! regulation of multicellular organism growth GO:0040014 65 50 0,000 0,24096882 0,25838149 ! proton transport GO:0015992 75 50 0,000 0,24096882 0,25826109 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 0,000 0,24096882 0,2581408 ! positive regulation of secretion GO:0051047 71 51 0,000 0,24514889 0,26249649 ! hydrogen transport GO:0006818 77 51 0,000 0,24514889 0,26237434 ! positive regulation of organelle organization GO:0010638 82 51 0,000 0,24514889 0,2622523 ! adult behavior GO:0030534 80 51 0,000 0,24514889 0,26213038 ! transition metal ion transport GO:0000041 74 52 0,000 0,24930618 0,26645177 ! regulation of cellular component size GO:0032535 74 52 0,000 0,24930618 0,26632802 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,24930618 0,26620437 ! establishment of organelle localization GO:0051656 85 52 0,000 0,24930618 0,26608084 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,25344081 0,27036821 ! regulation of neurotransmitter levels GO:0001505 73 53 0,000 0,25344081 0,27024287 ! kidney development GO:0001822 90 53 0,000 0,25344081 0,27011764 ! regulation of protein complex assembly GO:0043254 81 54 0,000 0,25755291 0,27437317 ! regulation of mitosis GO:0007088 84 54 0,000 0,25755291 0,27424615 GO:0051783|regulation of nuclear division, ! glucose catabolic process GO:0006007 66 54 0,000 0,25755291 0,27411924 ! DNA catabolic process GO:0006308 67 54 0,000 0,25755291 0,27399245 ! detection of external stimulus GO:0009581 66 54 0,000 0,25755291 0,27386578 ! cellular amino acid catabolic process GO:0009063 74 54 0,000 0,25755291 0,27373923 ! mesoderm development GO:0007498 76 55 0,000 0,26164258 0,27795748 ! nucleoside metabolic process GO:0009116 69 55 0,000 0,26164258 0,27782915 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,26164258 0,27770094 ! multicellular organism reproduction GO:0032504 83 57 0,000 0,26975518 0,28617939 GO:0048609|reproductive process in a multicellular organism, ! chromosome segregation GO:0007059 83 57 0,000 0,26975518 0,28604745 ! coenzyme biosynthetic process GO:0009108 67 57 0,000 0,26975518 0,28591563 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,26975518 0,28578393 ! camera-type eye development GO:0043010 88 57 0,000 0,26975518 0,28565235 ! secondary metabolic process GO:0019748 84 57 0,000 0,26975518 0,2855209 ! regulation of cytokine biosynthetic process GO:0042035 76 58 0,000 0,27377834 0,28964589 ! steroid hormone receptor signaling pathway GO:0030518 96 58 0,000 0,27377834 0,28951272 ! protein maturation by peptide bond cleavage GO:0051605 76 58 0,000 0,27377834 0,28937968 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 0,000 0,27777956 0,29347404 ! actin filament organization GO:0007015 95 59 0,000 0,27777956 0,29333929 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,27777956 0,29320467 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 0,000 0,28175896 0,29726863 ! embryonic limb morphogenesis GO:0030326 86 60 0,000 0,28175896 0,29713233 GO:0035113|embryonic appendage morphogenesis, ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,28175896 0,29699616 ! regulation of vesicle-mediated transport GO:0060627 79 60 0,000 0,28175896 0,29686011 ! regulation of cellular response to stress GO:0080135 85 61 0,000 0,28571667 0,30089209 ! lipoprotein metabolic process GO:0042157 89 61 0,000 0,28571667 0,30075439 ! urogenital system development GO:0001655 101 61 0,000 0,28571667 0,3006168 ! homeostasis of number of cells GO:0048872 84 61 0,000 0,28571667 0,30047935 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,28571667 0,30034202 ! extracellular matrix organization GO:0030198 103 61 0,000 0,28571667 0,30020481 ! amine catabolic process GO:0009310 90 62 0,000 0,28965279 0,30420156 ! neurotransmitter transport GO:0006836 81 62 0,000 0,28965279 0,30406272 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,28965279 0,303924 ! lymphocyte mediated immunity GO:0002449 88 62 0,000 0,28965279 0,30378542 ! organelle localization GO:0051640 96 62 0,000 0,28965279 0,30364695 ! cAMP-mediated signaling GO:0019933 97 63 0,000 0,29356745 0,30761054 ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 0,000 0,29356745 0,30747046 ! cell cycle checkpoint GO:0000075 108 64 0,000 0,29746076 0,31140634 ! appendage morphogenesis GO:0035107 93 64 0,000 0,29746076 0,31126467 GO:0035108|limb morphogenesis, ! regulation of actin cytoskeleton organization GO:0032956 97 64 0,000 0,29746076 0,31112312 ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,29746076 0,3109817 ! hexose catabolic process GO:0019320 82 64 0,000 0,29746076 0,31084041 ! appendage development GO:0048736 94 65 0,000 0,30133283 0,31474364 GO:0060173|limb development, ! B cell activation GO:0042113 104 65 0,000 0,30133283 0,31460077 ! defense response to bacterium GO:0042742 73 65 0,000 0,30133283 0,31445803 ! regulation of MAPKKK cascade GO:0043408 101 65 0,000 0,30133283 0,31431542 ! positive regulation of T cell activation GO:0050870 94 65 0,000 0,30133283 0,31417294 ! activation of immune response GO:0002253 83 65 0,000 0,30133283 0,31403059 ! regulation of actin filament-based process GO:0032970 99 66 0,000 0,30518378 0,31789977 ! antigen processing and presentation GO:0019882 96 66 0,000 0,30518378 0,31775586 ! regulation of Rho protein signal transduction GO:0035023 111 66 0,000 0,30518378 0,31761208 ! regulation of immune effector process GO:0002697 101 66 0,000 0,30518378 0,31746843 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,30901373 0,32130722 ! acute inflammatory response GO:0002526 92 68 0,000 0,31282278 0,32512083 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,31282278 0,32497398 ! intracellular protein transmembrane transport GO:0065002 102 68 0,000 0,31282278 0,32482727 ! regulation of Ras GTPase activity GO:0032318 110 68 0,000 0,31282278 0,32468069 ! rhythmic process GO:0048511 105 68 0,000 0,31282278 0,32453424 ! inorganic anion transport GO:0015698 93 68 0,000 0,31282278 0,32438792 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,31661106 0,32816829 ! response to metal ion GO:0010038 103 70 0,000 0,32037866 0,33192384 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 0,000 0,32037866 0,33177439 ! humoral immune response GO:0006959 86 70 0,000 0,32037866 0,33162508 ! eye development GO:0001654 111 70 0,000 0,32037866 0,3314759 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 0,000 0,32037866 0,33132686 ! muscle cell differentiation GO:0042692 104 71 0,000 0,32412572 0,3350513 ! leukocyte mediated immunity GO:0002443 99 71 0,000 0,32412572 0,33490078 ! steroid biosynthetic process GO:0006694 94 71 0,000 0,32412572 0,3347504 ! lymphocyte differentiation GO:0030098 113 71 0,000 0,32412572 0,33460015 ! monosaccharide catabolic process GO:0046365 91 71 0,000 0,32412572 0,33445004 ! regulation of blood pressure GO:0008217 107 73 0,000 0,33155859 0,34196626 ! tube morphogenesis GO:0035239 118 73 0,000 0,33155859 0,34181298 ! mitochondrion organization GO:0007005 104 73 0,000 0,33155859 0,34165984 ! cellular lipid catabolic process GO:0044242 105 73 0,000 0,33155859 0,34150683 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,33524464 0,34514891 ! digestion GO:0007586 97 74 0,000 0,33524464 0,34499448 ! protein import into nucleus GO:0006606 118 74 0,000 0,33524464 0,34484019 ! blood coagulation GO:0007596 116 75 0,000 0,33891057 0,34845521 GO:0050817|coagulation, ! response to inorganic substance GO:0010035 115 75 0,000 0,33891057 0,34829951 ! nuclear import GO:0051170 121 75 0,000 0,33891057 0,34814395 ! cofactor biosynthetic process GO:0051188 92 75 0,000 0,33891057 0,34798853 ! amine biosynthetic process GO:0009309 97 76 0,000 0,34255649 0,35157516 ! tRNA metabolic process GO:0006399 95 76 0,000 0,34255649 0,35141835 ! response to unfolded protein GO:0006986 99 76 0,000 0,34255649 0,35126167 ! regulation of adenylate cyclase activity GO:0045761 131 77 0,000 0,34618252 0,35482165 ! cholesterol metabolic process GO:0008203 109 77 0,000 0,34618252 0,3546636 ! protein ubiquitination GO:0016567 125 77 0,000 0,34618252 0,35450569 ! one-carbon metabolic process GO:0006730 110 77 0,000 0,34618252 0,35434792 ! nitrogen compound catabolic process GO:0044270 114 78 0,000 0,34978875 0,35787995 ! regulation of cyclase activity GO:0031279 132 78 0,000 0,34978875 0,35772082 ! regulation of cAMP biosynthetic process GO:0030817 136 79 0,000 0,3533753 0,36122808 ! cellular respiration GO:0045333 107 79 0,000 0,3533753 0,36106761 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,3533753 0,36090727 ! T cell activation GO:0042110 134 79 0,000 0,3533753 0,36074708 ! regulation of lyase activity GO:0051339 133 79 0,000 0,3533753 0,36058704 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,3533753 0,36042713 ! chromatin assembly GO:0031497 102 80 0,000 0,35694227 0,36390391 GO:0006334|nucleosome assembly, ! protein localization in nucleus GO:0034504 133 80 0,000 0,35694227 0,36374267 ! regulation of GTPase activity GO:0043087 129 80 0,000 0,35694227 0,36358158 ! regulation of cAMP metabolic process GO:0030814 141 81 0,000 0,36048976 0,36703252 ! hemostasis GO:0007599 125 81 0,000 0,36048976 0,36687011 ! mRNA transport GO:0051028 121 81 0,000 0,36048976 0,36670785 ! response to protein stimulus GO:0051789 111 81 0,000 0,36048976 0,36654574 ! vitamin metabolic process GO:0006766 103 81 0,000 0,36048976 0,36638376 ! detection of stimulus GO:0051606 108 82 0,000 0,36401789 0,36980616 ! regulation of nucleotide biosynthetic process GO:0030808 141 83 0,000 0,36752676 0,37320598 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! protein-DNA complex assembly GO:0065004 107 84 0,000 0,37101647 0,37658335 ! sterol metabolic process GO:0016125 120 84 0,000 0,37101647 0,37641724 ! rRNA metabolic process GO:0016072 107 85 0,000 0,37448712 0,37977089 GO:0006364|rRNA processing, ! transcription initiation GO:0006352 118 85 0,000 0,37448712 0,37960352 ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 0,000 0,37793882 0,38293361 ! nucleosome organization GO:0034728 114 87 0,000 0,38137167 0,38624168 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 0,000 0,38137167 0,38607167 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cellular defense response GO:0006968 102 87 0,000 0,38137167 0,38590182 ! female pregnancy GO:0007565 130 87 0,000 0,38137167 0,38573212 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 0,000 0,38478577 0,38901419 ! anatomical structure homeostasis GO:0060249 136 88 0,000 0,38478577 0,38884327 ! carboxylic acid catabolic process GO:0046395 122 88 0,000 0,38478577 0,3886725 GO:0016054|organic acid catabolic process, ! establishment of RNA localization GO:0051236 128 88 0,000 0,38478577 0,38850188 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! protein processing GO:0016485 114 88 0,000 0,38478577 0,38833141 ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 0,000 0,38818123 0,39158633 ! regulation of nucleotide metabolic process GO:0006140 150 89 0,000 0,38818123 0,39141466 ! leukocyte differentiation GO:0002521 143 90 0,000 0,39155814 0,39464668 ! protein modification by small protein conjugation GO:0032446 140 90 0,000 0,39155814 0,39447382 ! hormone metabolic process GO:0042445 121 90 0,000 0,39155814 0,39430111 ! RNA localization GO:0006403 135 91 0,000 0,39491661 0,39750906 ! ATP metabolic process GO:0046034 137 91 0,000 0,39491661 0,39733517 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 0,000 0,39825672 0,40052054 ! cell fate commitment GO:0045165 141 92 0,000 0,39825672 0,40034548 ! positive regulation of immune response GO:0050778 121 92 0,000 0,39825672 0,40017058 ! sulfur metabolic process GO:0006790 118 92 0,000 0,39825672 0,39999584 ! electron transport chain GO:0022900 123 94 0,000 0,40488232 0,40647287 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 0,000 0,41143572 0,41287179 ! protein modification by small protein conjugation or removal GO:0070647 148 96 0,000 0,41143572 0,41269173 ! protein maturation GO:0051604 129 96 0,000 0,41143572 0,41251183 ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,41468558 0,41558904 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! protein import GO:0017038 156 99 0,000 0,42113213 0,42186581 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 0,000 0,42432901 0,42488321 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 0,000 0,42432901 0,42469831 ! regulation of body fluid levels GO:0050878 154 100 0,000 0,42432901 0,42451358 ! protein localization in organelle GO:0033365 161 100 0,000 0,42432901 0,42432901