pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6798-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! insulin receptor signaling pathway GO:0008286 66 27 5,000 8,497E-10 2,076E-06 ! cellular response to insulin stimulus GO:0032869 85 38 5,000 7,651E-09 9,346E-06 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 3,000 1,504E-08 1,225E-05 ! induction of positive chemotaxis GO:0050930 17 9 3,000 2,7E-08 1,649E-05 ! response to insulin stimulus GO:0032868 98 47 5,000 2,892E-08 1,413E-05 ! glucan biosynthetic process GO:0009250 14 10 3,000 4,486E-08 1,826E-05 GO:0005978|glycogen biosynthetic process, ! regulation of positive chemotaxis GO:0050926 22 12 3,000 1,051E-07 3,668E-05 GO:0050927|positive regulation of positive chemotaxis, ! positive regulation of cell migration GO:0030335 137 58 5,000 1,053E-07 3,214E-05 ! response to peptide hormone stimulus GO:0043434 129 64 5,000 1,913E-07 5,193E-05 ! positive regulation of cell motion GO:0051272 157 65 5,000 2,101E-07 5,132E-05 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 5,000 2,757E-07 6,124E-05 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 5,000 3,01E-07 6,129E-05 ! glycogen metabolic process GO:0005977 63 38 4,000 3,714E-07 6,979E-05 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 5,000 3,886E-07 6,781E-05 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 5,000 3,886E-07 6,329E-05 ! glucan metabolic process GO:0044042 64 39 4,000 4,247E-07 6,484E-05 GO:0006073|cellular glucan metabolic process, ! positive regulation of ligase activity GO:0051351 130 77 5,000 5,804E-07 8,341E-05 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 5,000 6,762E-07 9,177E-05 ! energy reserve metabolic process GO:0006112 76 44 4,000 7,886E-07 1,014E-04 ! induction of apoptosis by intracellular signals GO:0008629 95 45 4,000 8,844E-07 1,08E-04 ! regulation of ligase activity GO:0051340 147 84 5,000 9,732E-07 1,132E-04 ! cellular response to hormone stimulus GO:0032870 182 85 5,000 1,044E-06 1,159E-04 ! positive regulation of locomotion GO:0040017 44 22 3,000 1,507E-06 1,601E-04 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 5,000 1,774E-06 1,805E-04 GO:0010498|proteasomal protein catabolic process, ! regulation of chemotaxis GO:0050920 45 23 3,000 1,819E-06 1,777E-04 ! centrosome duplication GO:0051298 14 7 2,000 1,981E-06 1,862E-04 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 2,000 1,981E-06 1,793E-04 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 3,000 2,176E-06 1,898E-04 ! negative regulation of phosphorylation GO:0042326 52 24 3,000 2,176E-06 1,833E-04 ! regulation of behavior GO:0050795 48 25 3,000 2,583E-06 2,103E-04 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 3,000 3,043E-06 2,398E-04 GO:0045936|negative regulation of phosphate metabolic process, ! cellular polysaccharide metabolic process GO:0044264 93 58 4,000 3,185E-06 2,432E-04 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 3,000 3,561E-06 2,636E-04 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 3,000 4,142E-06 2,976E-04 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 2,000 4,729E-06 3,301E-04 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 4,000 6,528E-06 4,43E-04 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 2,000 6,736E-06 4,447E-04 ! negative regulation of ligase activity GO:0051352 116 68 4,000 7,025E-06 4,516E-04 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! cellular carbohydrate biosynthetic process GO:0034637 47 32 3,000 7,188E-06 4,503E-04 ! negative regulation of protein kinase activity GO:0006469 144 69 4,000 7,55E-06 4,611E-04 ! negative regulation of kinase activity GO:0033673 145 70 4,000 8,105E-06 4,83E-04 ! chondrocyte differentiation GO:0002062 27 11 2,000 9,235E-06 5,372E-04 ! negative regulation of glucose import GO:0046325 18 11 2,000 9,235E-06 5,247E-04 GO:0010829|negative regulation of glucose transport, ! negative regulation of transferase activity GO:0051348 155 74 4,000 1,065E-05 5,916E-04 ! mammary gland development GO:0030879 93 40 3,000 1,783E-05 9,682E-04 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 2,000 2,02E-05 1,073E-03 ! regulation of the force of heart contraction GO:0002026 31 15 2,000 2,518E-05 1,309E-03 ! positive regulation of response to external stimulus GO:0032103 88 44 3,000 2,617E-05 1,332E-03 ! regulation of epithelial cell proliferation GO:0050678 122 45 3,000 2,864E-05 1,428E-03 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 3,000 3,127E-05 1,528E-03 ! polysaccharide biosynthetic process GO:0000271 79 46 3,000 3,127E-05 1,498E-03 ! carbohydrate biosynthetic process GO:0016051 158 94 4,000 3,412E-05 1,603E-03 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 2,000 3,742E-05 1,725E-03 ! neutrophil chemotaxis GO:0030593 29 17 2,000 3,742E-05 1,693E-03 ! centrosome cycle GO:0007098 26 18 2,000 4,477E-05 1,989E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 2,000 4,477E-05 1,953E-03 ! cartilage development GO:0051216 99 53 3,000 5,495E-05 2,355E-03 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 2,000 6,219E-05 2,62E-03 ! regulation of glucose import GO:0046324 30 20 2,000 6,219E-05 2,575E-03 GO:0010827|regulation of glucose transport, ! response to UV GO:0009411 120 55 3,000 6,362E-05 2,59E-03 ! phosphatidylinositol metabolic process GO:0046488 47 21 2,000 7,235E-05 2,898E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 2,000 7,235E-05 2,851E-03 ! positive regulation of inflammatory response GO:0050729 41 21 2,000 7,235E-05 2,806E-03 ! inactivation of MAPK activity GO:0000188 45 22 2,000 8,354E-05 3,189E-03 ! positive regulation of intracellular transport GO:0032388 42 22 2,000 8,354E-05 3,14E-03 ! skeletal system morphogenesis GO:0048705 118 63 3,000 1,085E-04 4,015E-03 ! calcium-independent cell-cell adhesion GO:0016338 36 24 2,000 1,092E-04 3,981E-03 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 2,000 1,092E-04 3,922E-03 ! protein amino acid autophosphorylation GO:0046777 157 64 3,000 1,154E-04 4,084E-03 ! microtubule organizing center organization GO:0031023 42 26 2,000 1,394E-04 4,867E-03 GO:0051297|centrosome organization, ! negative regulation of bone resorption GO:0045779 10 5 1,000 1,485E-04 5,11E-03 ! positive regulation of glycolysis GO:0045821 13 5 1,000 1,485E-04 5,039E-03 ! skeletal myofibril assembly GO:0014866 12 5 1,000 1,485E-04 4,97E-03 ! cardiac muscle fiber development GO:0048739 12 5 1,000 1,485E-04 4,903E-03 ! microvillus organization GO:0032528 8 5 1,000 1,485E-04 4,837E-03 GO:0030033|microvillus assembly, ! polyol catabolic process GO:0046174 9 5 1,000 1,485E-04 4,774E-03 GO:0019405|alditol catabolic process, ! positive regulation of filopodium assembly GO:0051491 16 5 1,000 1,485E-04 4,712E-03 GO:0051489|regulation of filopodium assembly, ! morphogenesis of an epithelial sheet GO:0002011 11 5 1,000 1,485E-04 4,651E-03 ! regulation of phospholipase A2 activity GO:0032429 15 5 1,000 1,485E-04 4,592E-03 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 1,000 1,485E-04 4,535E-03 ! inner cell mass cell proliferation GO:0001833 5 5 1,000 1,485E-04 4,479E-03 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 1,000 1,485E-04 4,424E-03 ! regulation of sensory perception GO:0051931 8 5 1,000 1,485E-04 4,371E-03 GO:0051930|regulation of sensory perception of pain, ! protein insertion into membrane GO:0051205 17 5 1,000 1,485E-04 4,319E-03 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 3,000 1,546E-04 4,444E-03 ! negative regulation of protein modification process GO:0031400 66 28 2,000 1,747E-04 4,963E-03 ! activation of MAPKKK activity GO:0000185 12 6 1,000 2,222E-04 6,239E-03 ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 1,000 2,222E-04 6,168E-03 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! negative regulation of gliogenesis GO:0014014 18 6 1,000 2,222E-04 6,099E-03 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 1,000 2,222E-04 6,031E-03 ! response to UV-C GO:0010225 14 6 1,000 2,222E-04 5,965E-03 ! phosphoinositide metabolic process GO:0030384 146 77 3,000 2,363E-04 6,275E-03 ! leukocyte chemotaxis GO:0030595 55 33 2,000 2,869E-04 7,536E-03 GO:0060326|cell chemotaxis, ! positive regulation of phosphorylation GO:0042327 149 81 3,000 2,87E-04 7,46E-03 ! cytokinesis during cell cycle GO:0033205 14 7 1,000 3,103E-04 7,979E-03 ! sleep GO:0030431 16 7 1,000 3,103E-04 7,896E-03 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 1,000 3,103E-04 7,815E-03 ! Golgi to plasma membrane transport GO:0006893 14 7 1,000 3,103E-04 7,735E-03 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 3,103E-04 7,657E-03 ! N-terminal protein amino acid acetylation GO:0006474 14 7 1,000 3,103E-04 7,58E-03 ! mRNA stabilization GO:0048255 18 7 1,000 3,103E-04 7,505E-03 GO:0043489|RNA stabilization, ! male sex determination GO:0030238 15 7 1,000 3,103E-04 7,432E-03 ! positive regulation of mitotic cell cycle GO:0045931 14 7 1,000 3,103E-04 7,359E-03 ! cranial nerve morphogenesis GO:0021602 12 7 1,000 3,103E-04 7,289E-03 ! negative regulation of MAP kinase activity GO:0043407 78 34 2,000 3,137E-04 7,299E-03 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 3,000 3,152E-04 7,263E-03 GO:0045937|positive regulation of phosphate metabolic process, ! regulation of smooth muscle cell proliferation GO:0048660 64 37 2,000 4,039E-04 9,222E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 1,000 4,127E-04 9,334E-03 ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 1,000 4,127E-04 9,249E-03 ! male meiosis GO:0007140 9 8 1,000 4,127E-04 9,165E-03 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 1,000 4,127E-04 9,082E-03 ! regulation of lipid kinase activity GO:0043550 17 8 1,000 4,127E-04 9,001E-03 ! T-helper 1 type immune response GO:0042088 12 8 1,000 4,127E-04 8,921E-03 ! ER overload response GO:0006983 13 8 1,000 4,127E-04 8,843E-03 ! positive regulation of endothelial cell migration GO:0010595 19 8 1,000 4,127E-04 8,766E-03 ! cerebral cortex neuron differentiation GO:0021895 16 8 1,000 4,127E-04 8,691E-03 ! regulation of vascular permeability GO:0043114 12 8 1,000 4,127E-04 8,616E-03 ! regulation of T cell differentiation in the thymus GO:0033081 14 8 1,000 4,127E-04 8,543E-03 ! regulation of respiratory burst GO:0060263 12 8 1,000 4,127E-04 8,472E-03 ! blastocyst growth GO:0001832 19 8 1,000 4,127E-04 8,401E-03 ! B cell receptor signaling pathway GO:0050853 22 8 1,000 4,127E-04 8,332E-03 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 1,000 4,127E-04 8,263E-03 ! embryonic skeletal system morphogenesis GO:0048704 68 38 2,000 4,373E-04 8,685E-03 ! gland development GO:0048732 220 91 3,000 4,475E-04 8,817E-03 ! positive regulation of MAP kinase activity GO:0043406 174 93 3,000 4,86E-04 9,498E-03 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 5,292E-04 0,01026069 ! Golgi to endosome transport GO:0006895 25 9 1,000 5,292E-04 0,0101799 ! regulation of glycolysis GO:0006110 20 9 1,000 5,292E-04 0,01010037 ! microtubule bundle formation GO:0001578 22 9 1,000 5,292E-04 0,01002207 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 1,000 5,292E-04 9,945E-03 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 1,000 5,292E-04 9,869E-03 ! response to amine stimulus GO:0014075 13 9 1,000 5,292E-04 9,794E-03 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of intracellular protein transport GO:0033157 86 42 2,000 5,884E-04 0,0108075 ! interphase of mitotic cell cycle GO:0051329 224 98 3,000 5,923E-04 0,01079851 ! regulation of developmental growth GO:0048638 16 10 1,000 6,598E-04 0,01194033 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 1,000 6,598E-04 0,01185254 ! positive regulation of B cell proliferation GO:0030890 18 10 1,000 6,598E-04 0,01176602 ! regulation of smooth muscle cell migration GO:0014910 27 10 1,000 6,598E-04 0,01168076 ! elastic fiber assembly GO:0048251 17 10 1,000 6,598E-04 0,01159673 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 1,000 6,598E-04 0,01151389 ! lung alveolus development GO:0048286 26 10 1,000 6,598E-04 0,01143223 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 1,000 6,598E-04 0,01135173 ! multicellular organism growth GO:0035264 19 10 1,000 6,598E-04 0,01127234 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 1,000 6,598E-04 0,01119406 ! motor axon guidance GO:0008045 22 10 1,000 6,598E-04 0,01111686 ! regulation of bone resorption GO:0045124 25 10 1,000 6,598E-04 0,01104072 ! protein heterooligomerization GO:0051291 17 10 1,000 6,598E-04 0,01096561 ! regulation of gliogenesis GO:0014013 23 10 1,000 6,598E-04 0,01089152 GO:0045685|regulation of glial cell differentiation, ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 1,000 6,598E-04 0,01081842 GO:0043470|regulation of carbohydrate catabolic process, ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 1,000 6,598E-04 0,0107463 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 2,000 7,692E-04 0,01244538 ! regulation of gene-specific transcription GO:0032583 102 46 2,000 7,692E-04 0,01236351 ! leukocyte migration GO:0050900 75 46 2,000 7,692E-04 0,0122827 ! positive regulation of protein transport GO:0051222 80 46 2,000 7,692E-04 0,01220294 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 1,000 8,044E-04 0,01267833 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 1,000 8,044E-04 0,01259706 ! blood vessel remodeling GO:0001974 30 11 1,000 8,044E-04 0,01251682 ! positive regulation of endothelial cell proliferation GO:0001938 23 11 1,000 8,044E-04 0,0124376 ! peptide or protein amino-terminal blocking GO:0018409 22 11 1,000 8,044E-04 0,01235938 ! neuroblast proliferation GO:0007405 25 11 1,000 8,044E-04 0,01228213 ! positive regulation of leukocyte migration GO:0002687 28 11 1,000 8,044E-04 0,01220585 ! oocyte development GO:0048599 20 11 1,000 8,044E-04 0,0121305 ! T cell receptor signaling pathway GO:0050852 29 11 1,000 8,044E-04 0,01205608 ! regulation of embryonic development GO:0045995 35 11 1,000 8,044E-04 0,01198257 ! positive regulation of cell cycle GO:0045787 96 48 2,000 8,715E-04 0,01290374 ! positive regulation of defense response GO:0031349 88 48 2,000 8,715E-04 0,01282601 ! regulation of inflammatory response GO:0050727 84 48 2,000 8,715E-04 0,0127492 ! regulation of mast cell proliferation GO:0070666 89 49 2,000 9,257E-04 0,01346167 ! positive regulation of cellular catabolic process GO:0031331 34 12 1,000 9,628E-04 0,01391817 ! virus-host interaction GO:0019048 30 12 1,000 9,628E-04 0,0138363 ! regulation of B cell proliferation GO:0030888 22 12 1,000 9,628E-04 0,01375538 ! regulation of cell projection assembly GO:0060491 33 12 1,000 9,628E-04 0,01367541 ! hippocampus development GO:0021766 29 12 1,000 9,628E-04 0,01359636 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 1,000 9,628E-04 0,01351822 ! cranial nerve development GO:0021545 23 12 1,000 9,628E-04 0,01344097 ! histone acetylation GO:0016573 27 12 1,000 9,628E-04 0,0133646 ! autonomic nervous system development GO:0048483 24 12 1,000 9,628E-04 0,0132891 ! peptidyl-lysine modification GO:0018205 21 12 1,000 9,628E-04 0,01321444 ! regulation of leukocyte migration GO:0002685 29 12 1,000 9,628E-04 0,01314062 ! oocyte differentiation GO:0009994 21 12 1,000 9,628E-04 0,01306761 ! negative regulation of mast cell proliferation GO:0070667 24 12 1,000 9,628E-04 0,01299542 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 1,000 9,628E-04 0,01292401 ! localization within membrane GO:0051668 26 12 1,000 9,628E-04 0,01285339 ! induction of apoptosis by extracellular signals GO:0008624 99 50 2,000 9,82E-04 0,01303868 ! double-strand break repair via homologous recombination GO:0000724 19 13 1,000 1,135E-03 0,01498793 GO:0000725|recombinational repair, ! cartilage condensation GO:0001502 22 13 1,000 1,135E-03 0,01490735 ! indolalkylamine metabolic process GO:0006586 19 13 1,000 1,135E-03 0,01482763 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! response to X-ray GO:0010165 28 13 1,000 1,135E-03 0,01474876 ! cellular carbohydrate catabolic process GO:0044275 17 13 1,000 1,135E-03 0,01467073 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 1,000 1,135E-03 0,01459351 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of monooxygenase activity GO:0032768 35 13 1,000 1,135E-03 0,01451711 ! regulation of mRNA stability GO:0043488 32 13 1,000 1,135E-03 0,0144415 ! regulation of leukocyte proliferation GO:0070663 97 53 2,000 1,164E-03 0,01473159 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! embryonic skeletal system development GO:0048706 101 54 2,000 1,229E-03 0,01547393 ! regulation of muscle contraction GO:0006937 94 54 2,000 1,229E-03 0,01539457 ! regulation of S phase GO:0033261 26 14 1,000 1,321E-03 0,0164626 ! response to gamma radiation GO:0010332 30 14 1,000 1,321E-03 0,01637904 ! regulation of RNA stability GO:0043487 33 14 1,000 1,321E-03 0,01629632 ! regulation of DNA replication GO:0006275 105 56 2,000 1,366E-03 0,0167635 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 2,000 1,437E-03 0,01755663 ! regulation of intracellular transport GO:0032386 108 57 2,000 1,437E-03 0,01746928 ! N-terminal protein amino acid modification GO:0031365 30 15 1,000 1,52E-03 0,01838425 ! negative regulation of bone remodeling GO:0046851 34 15 1,000 1,52E-03 0,01829368 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 1,000 1,52E-03 0,01820401 ! actin cytoskeleton reorganization GO:0031532 38 15 1,000 1,52E-03 0,01811521 ! dopamine metabolic process GO:0042417 35 15 1,000 1,52E-03 0,01802727 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 1,733E-03 0,02045097 ! startle response GO:0001964 28 16 1,000 1,733E-03 0,02035265 ! positive regulation of protein import into nucleus GO:0042307 34 16 1,000 1,733E-03 0,02025526 ! negative regulation of tissue remodeling GO:0034104 37 16 1,000 1,733E-03 0,02015881 ! negative regulation of leukocyte proliferation GO:0070664 32 16 1,000 1,733E-03 0,02006327 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! regulation of heart contraction GO:0008016 123 61 2,000 1,748E-03 0,02014346 ! negative regulation of response to stimulus GO:0048585 106 61 2,000 1,748E-03 0,02004889 ! signal complex assembly GO:0007172 47 17 1,000 1,959E-03 0,02236266 ! activation of MAPKK activity GO:0000186 43 17 1,000 1,959E-03 0,02225865 ! cardiac muscle tissue development GO:0048738 34 17 1,000 1,959E-03 0,0221556 ! negative regulation of microtubule depolymerization GO:0007026 50 17 1,000 1,959E-03 0,0220535 GO:0031114|regulation of microtubule depolymerization, ! negative regulation of homeostatic process GO:0032845 36 17 1,000 1,959E-03 0,02195234 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 1,000 1,959E-03 0,0218521 ! integrin-mediated signaling pathway GO:0007229 160 64 2,000 2,007E-03 0,02228164 ! limbic system development GO:0021761 40 18 1,000 2,198E-03 0,02429927 ! negative regulation of protein catabolic process GO:0042177 42 18 1,000 2,198E-03 0,02418981 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 1,000 2,198E-03 0,02408134 ! nerve development GO:0021675 34 18 1,000 2,198E-03 0,02397383 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 1,000 2,198E-03 0,02386728 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 1,000 2,451E-03 0,02648974 ! memory GO:0007613 34 19 1,000 2,451E-03 0,02637305 ! regulation of postsynaptic membrane potential GO:0060078 38 19 1,000 2,451E-03 0,02625738 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 1,000 2,451E-03 0,02614272 ! neuromuscular junction development GO:0007528 43 19 1,000 2,451E-03 0,02602905 ! regulation of endothelial cell migration GO:0010594 45 19 1,000 2,451E-03 0,02591637 ! visual learning GO:0008542 38 19 1,000 2,451E-03 0,02580466 ! lung development GO:0030324 165 69 2,000 2,488E-03 0,02608597 ! phosphoinositide phosphorylation GO:0046854 40 20 1,000 2,716E-03 0,02835464 ! protein amino acid acetylation GO:0006473 41 20 1,000 2,716E-03 0,02823399 ! regulation of carbohydrate metabolic process GO:0006109 37 20 1,000 2,716E-03 0,02811435 GO:0010675|regulation of cellular carbohydrate metabolic process, ! peptidyl-serine phosphorylation GO:0018105 44 20 1,000 2,716E-03 0,02799572 ! negative regulation of T cell activation GO:0050868 41 20 1,000 2,716E-03 0,0278781 ! binding of sperm to zona pellucida GO:0007339 22 20 1,000 2,716E-03 0,02776145 ! negative regulation of translation GO:0017148 32 20 1,000 2,716E-03 0,02764578 ! respiratory tube development GO:0030323 171 72 2,000 2,808E-03 0,0284661 ! lipid phosphorylation GO:0046834 43 21 1,000 2,994E-03 0,03022645 ! smooth muscle contraction GO:0006939 48 21 1,000 2,994E-03 0,03010206 ! sperm-egg recognition GO:0035036 23 21 1,000 2,994E-03 0,02997869 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 2,000 3,035E-03 0,03026418 ! respiratory system development GO:0060541 175 74 2,000 3,035E-03 0,03014116 ! cell-matrix adhesion GO:0007160 181 76 2,000 3,273E-03 0,03237206 ! microtubule-based transport GO:0010970 59 22 1,000 3,285E-03 0,03236239 ! glutamate signaling pathway GO:0007215 48 22 1,000 3,285E-03 0,03223242 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 1,000 3,285E-03 0,03210349 ! cell aging GO:0007569 48 22 1,000 3,285E-03 0,03197558 ! peptidyl-serine modification GO:0018209 50 22 1,000 3,285E-03 0,0318487 ! positive regulation of B cell activation GO:0050871 42 22 1,000 3,285E-03 0,03172281 ! regulation of catabolic process GO:0009894 173 77 2,000 3,396E-03 0,03266399 ! positive regulation of DNA replication GO:0045740 44 23 1,000 3,589E-03 0,03438412 ! gluconeogenesis GO:0006094 38 23 1,000 3,589E-03 0,03424981 ! glycerol metabolic process GO:0006071 40 23 1,000 3,589E-03 0,03411654 ! visual behavior GO:0007632 46 23 1,000 3,589E-03 0,03398431 ! response to ethanol GO:0045471 47 23 1,000 3,589E-03 0,03385309 ! cellular response to reactive oxygen species GO:0034614 35 23 1,000 3,589E-03 0,03372289 ! cell-cell recognition GO:0009988 28 23 1,000 3,589E-03 0,03359368 ! protein oligomerization GO:0051259 149 79 2,000 3,651E-03 0,03404101 ! positive regulation of cell adhesion GO:0045785 61 24 1,000 3,905E-03 0,03627677 ! regulation of cellular catabolic process GO:0031329 55 24 1,000 3,905E-03 0,03613936 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 1,000 3,905E-03 0,03600299 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! sex determination GO:0007530 48 24 1,000 3,905E-03 0,03586764 ! membrane depolarization GO:0051899 45 24 1,000 3,905E-03 0,0357333 ! pallium development GO:0021543 56 24 1,000 3,905E-03 0,03559997 ! oogenesis GO:0048477 44 24 1,000 3,905E-03 0,03546763 ! regulation of oxidoreductase activity GO:0051341 48 24 1,000 3,905E-03 0,03533627 ! negative regulation of catabolic process GO:0009895 52 24 1,000 3,905E-03 0,03520587 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 1,000 3,905E-03 0,03507644 ! response to hypoxia GO:0001666 178 81 2,000 3,917E-03 0,03504982 ! cell-substrate adhesion GO:0031589 189 82 2,000 4,054E-03 0,03614618 ! response to oxygen levels GO:0070482 183 83 2,000 4,194E-03 0,0372603 ! positive regulation of fibroblast proliferation GO:0048146 48 25 1,000 4,234E-03 0,03747879 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 1,000 4,234E-03 0,03734349 ! vasculogenesis GO:0001570 49 25 1,000 4,234E-03 0,03720916 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 1,000 4,234E-03 0,03707579 ! negative regulation of DNA replication GO:0008156 45 25 1,000 4,234E-03 0,03694338 ! interaction with host GO:0051701 66 25 1,000 4,234E-03 0,03681191 ! protein tetramerization GO:0051262 57 25 1,000 4,234E-03 0,03668137 ! negative regulation of transport GO:0051051 164 85 2,000 4,483E-03 0,03870336 ! myelination GO:0042552 50 26 1,000 4,575E-03 0,03935834 ! pyruvate metabolic process GO:0006090 43 26 1,000 4,575E-03 0,03922024 ! regulation of transcription factor import into nucleus GO:0042990 58 26 1,000 4,575E-03 0,03908311 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 1,000 4,575E-03 0,03894693 ! response to endoplasmic reticulum stress GO:0034976 46 26 1,000 4,575E-03 0,0388117 ! negative regulation of cell development GO:0010721 83 26 1,000 4,575E-03 0,0386774 GO:0050768|negative regulation of neurogenesis, ! blastocyst development GO:0001824 50 26 1,000 4,575E-03 0,03854403 ! alditol metabolic process GO:0019400 44 26 1,000 4,575E-03 0,03841158 ! regulation of protein transport GO:0051223 165 87 2,000 4,784E-03 0,04002858 GO:0070201|regulation of establishment of protein localization, ! positive regulation of cell projection organization GO:0031346 66 27 1,000 4,929E-03 0,04109699 ! regulation of endothelial cell proliferation GO:0001936 60 27 1,000 4,929E-03 0,0409572 ! cellular response to oxidative stress GO:0034599 43 27 1,000 4,929E-03 0,04081837 ! negative regulation of lymphocyte activation GO:0051250 55 27 1,000 4,929E-03 0,04068047 ! positive regulation of protein modification process GO:0031401 156 90 2,000 5,258E-03 0,04325269 ! regulation of fibroblast proliferation GO:0048145 56 28 1,000 5,295E-03 0,04340554 ! spliceosomal snRNP biogenesis GO:0000387 40 28 1,000 5,295E-03 0,04326037 ! protein amino acid acylation GO:0043543 59 28 1,000 5,295E-03 0,04311617 ! vesicle docking GO:0048278 55 28 1,000 5,295E-03 0,04297292 ! dendrite development GO:0016358 67 28 1,000 5,295E-03 0,04283063 ! peptidyl-tyrosine modification GO:0018212 57 28 1,000 5,295E-03 0,04268927 ! ossification GO:0001503 205 91 2,000 5,422E-03 0,04357471 ! bone development GO:0060348 206 92 2,000 5,589E-03 0,0447699 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 1,000 5,672E-03 0,045287 ! catechol metabolic process GO:0009712 55 29 1,000 5,672E-03 0,04513949 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! ER-nuclear signaling pathway GO:0006984 52 29 1,000 5,672E-03 0,04499293 ! response to organic cyclic substance GO:0014070 58 29 1,000 5,672E-03 0,04484732 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 1,000 5,672E-03 0,04470266 ! somitogenesis GO:0001756 52 29 1,000 5,672E-03 0,04455892 ! negative regulation of neuron differentiation GO:0045665 46 29 1,000 5,672E-03 0,0444161 ! regulation of membrane potential GO:0042391 179 94 2,000 5,933E-03 0,04630514 ! phenol metabolic process GO:0018958 56 30 1,000 6,062E-03 0,04716592 ! myofibril assembly GO:0030239 50 30 1,000 6,062E-03 0,04701619 GO:0055002|striated muscle cell development, ! immune response-activating signal transduction GO:0002757 58 30 1,000 6,062E-03 0,0468674 GO:0002764|immune response-regulating signal transduction, ! regulation of B cell activation GO:0050864 55 30 1,000 6,062E-03 0,04671956 ! regulation of defense response GO:0031347 171 95 2,000 6,109E-03 0,04693134 ! sex differentiation GO:0007548 171 96 2,000 6,288E-03 0,04815801 ! cellular response to extracellular stimulus GO:0031668 52 31 1,000 6,464E-03 0,04934825 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 1,000 6,464E-03 0,04919452 ! ensheathment of neurons GO:0007272 64 31 1,000 6,464E-03 0,04904174 GO:0008366|axon ensheathment, ! negative regulation of leukocyte activation GO:0002695 60 31 1,000 6,464E-03 0,04888991 ! regulation of DNA metabolic process GO:0051052 188 97 2,000 6,471E-03 0,04879095 ! regulation of protein localization GO:0032880 188 97 2,000 6,471E-03 0,04864082 ! regulation of protein import into nucleus GO:0042306 69 32 1,000 6,877E-03 0,05153868 ! muscle cell development GO:0055001 52 32 1,000 6,877E-03 0,05138107 ! hexose biosynthetic process GO:0019319 53 32 1,000 6,877E-03 0,05122442 ! peripheral nervous system development GO:0007422 68 32 1,000 6,877E-03 0,05106872 ! hindbrain development GO:0030902 65 32 1,000 6,877E-03 0,05091397 ! positive regulation of catabolic process GO:0009896 72 32 1,000 6,877E-03 0,05076015 ! skeletal muscle tissue development GO:0007519 223 100 2,000 7,037E-03 0,05178282 GO:0060538|skeletal muscle organ development, ! response to ionizing radiation GO:0010212 74 33 1,000 7,303E-03 0,05357469 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 1,000 7,739E-03 0,05660926 ! negative regulation of DNA metabolic process GO:0051053 65 35 1,000 8,188E-03 0,05970967 ! regulation of synaptic plasticity GO:0048167 78 35 1,000 8,188E-03 0,05953196 ! membrane docking GO:0022406 69 35 1,000 8,188E-03 0,05935531 ! telencephalon development GO:0021537 81 35 1,000 8,188E-03 0,0591797 ! calcium-mediated signaling GO:0019722 67 35 1,000 8,188E-03 0,05900513 ! monosaccharide biosynthetic process GO:0046364 57 36 1,000 8,648E-03 0,06213494 ! actomyosin structure organization GO:0031032 68 37 1,000 9,119E-03 0,06532753 ! tissue remodeling GO:0048771 78 37 1,000 9,119E-03 0,06513651 ! female gonad development GO:0008585 71 37 1,000 9,119E-03 0,06494661 ! regulation of microtubule-based process GO:0032886 86 37 1,000 9,119E-03 0,06475781 ! negative regulation of cell activation GO:0050866 69 37 1,000 9,119E-03 0,06457011 ! positive regulation of DNA metabolic process GO:0051054 77 38 1,000 9,601E-03 0,06778882 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 1,000 9,601E-03 0,06759346 ! carbohydrate homeostasis GO:0033500 59 39 1,000 0,0100943 0,07086317 GO:0042593|glucose homeostasis, ! positive regulation of leukocyte proliferation GO:0070665 70 39 1,000 0,0100943 0,07066012 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! learning GO:0007612 82 40 1,000 0,01059878 0,07397948 ! development of primary female sexual characteristics GO:0046545 80 40 1,000 0,01059878 0,07376872 GO:0046660|female sex differentiation, ! regulation of action potential in neuron GO:0019228 80 40 1,000 0,01059878 0,07355915 ! alcohol biosynthetic process GO:0046165 65 42 1,000 0,0116405 0,08056018 ! regulation of T cell differentiation GO:0045580 78 42 1,000 0,0116405 0,08033261 ! dorsal/ventral pattern formation GO:0009953 75 42 1,000 0,0116405 0,08010632 ! cytokinesis GO:0000910 84 42 1,000 0,0116405 0,07988131 ! positive regulation of transcription factor activity GO:0051091 71 43 1,000 0,01217756 0,08333274 GO:0090047|positive regulation of transcription regulator activity, ! glucose transport GO:0015758 66 43 1,000 0,01217756 0,08309997 ! striated muscle cell differentiation GO:0051146 91 43 1,000 0,01217756 0,0828685 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 1,000 0,01217756 0,08263831 ! regulation of T cell proliferation GO:0042129 80 43 1,000 0,01217756 0,08240939 ! segmentation GO:0035282 78 43 1,000 0,01217756 0,08218174 ! response to reactive oxygen species GO:0000302 75 44 1,000 0,01272531 0,08564167 ! negative regulation of protein complex disassembly GO:0043242 113 44 1,000 0,01272531 0,08540639 ! hexose transport GO:0008645 68 44 1,000 0,01272531 0,0851724 GO:0015749|monosaccharide transport, ! striated muscle contraction GO:0006941 85 44 1,000 0,01272531 0,08493969 ! double-strand break repair GO:0006302 85 44 1,000 0,01272531 0,08470825 ! female gamete generation GO:0007292 71 45 1,000 0,01328364 0,08818462 ! polyol metabolic process GO:0019751 77 45 1,000 0,01328364 0,08794564 ! developmental growth GO:0048589 88 45 1,000 0,01328364 0,08770794 ! negative regulation of cell migration GO:0030336 122 46 1,000 0,01385248 0,09121727 ! endosome transport GO:0016197 127 48 1,000 0,0150213 0,09864797 ! positive regulation of DNA binding GO:0043388 83 48 1,000 0,0150213 0,0983835 ! vascular process in circulatory system GO:0003018 85 48 1,000 0,0150213 0,09812044 ! regulation of lymphocyte differentiation GO:0045619 92 49 1,000 0,01562111 0,10176636 ! protein homooligomerization GO:0051260 84 49 1,000 0,01562111 0,1014957 ! regulation of action potential GO:0001508 102 50 1,000 0,01623108 0,1051791 ! regulation of gene expression, epigenetic GO:0040029 116 50 1,000 0,01623108 0,10490085 ! regulation of cell projection organization GO:0031344 135 51 1,000 0,0168511 0,10862069 ! negative regulation of immune system process GO:0002683 101 51 1,000 0,0168511 0,10833484 ! positive regulation of binding GO:0051099 88 52 1,000 0,0174811 0,11209012 ! response to estrogen stimulus GO:0043627 98 52 1,000 0,0174811 0,11179669 ! regulation of protein complex disassembly GO:0043244 127 52 1,000 0,0174811 0,11150479 ! DNA-dependent DNA replication GO:0006261 82 52 1,000 0,0174811 0,11121442 ! histone modification GO:0016570 104 52 1,000 0,0174811 0,11092555 ! positive regulation of growth GO:0045927 96 53 1,000 0,018121 0,11468807 ! synapse organization GO:0050808 102 53 1,000 0,018121 0,11439172 ! regulation of angiogenesis GO:0045765 125 54 1,000 0,0187707 0,11818766 ! activation of phospholipase C activity GO:0007202 110 54 1,000 0,0187707 0,11788384 GO:0010863|positive regulation of phospholipase C activity, ! neuromuscular process GO:0050905 107 54 1,000 0,0187707 0,11758157 ! covalent chromatin modification GO:0016569 115 54 1,000 0,0187707 0,11728085 ! regulation of cell shape GO:0008360 142 54 1,000 0,0187707 0,11698167 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 0,01926348 0,11974728 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 0,01926348 0,11944335 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 0,01926348 0,11914096 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,01926348 0,1188401 ! positive regulation of helicase activity GO:0051096 12 5 0,000 0,01926348 0,11854076 ! neuron fate determination GO:0048664 7 5 0,000 0,01926348 0,11824292 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01926348 0,11794657 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 0,01926348 0,1176517 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 0,01926348 0,11735831 ! polyol transport GO:0015791 12 5 0,000 0,01926348 0,11706637 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,01926348 0,11677588 ! response to superoxide GO:0000303 10 5 0,000 0,01926348 0,11648683 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 0,01926348 0,11619921 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 0,01926348 0,11591301 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,01926348 0,11562821 ! female meiosis GO:0007143 10 5 0,000 0,01926348 0,11534481 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 0,01926348 0,11506279 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,01926348 0,11478215 ! hypothalamus development GO:0021854 9 5 0,000 0,01926348 0,11450287 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 0,01926348 0,11422495 ! cobalt ion transport GO:0006824 11 5 0,000 0,01926348 0,11394838 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 0,01926348 0,11367314 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 0,01926348 0,11339923 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,01926348 0,11312664 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,01926348 0,11285535 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 0,01926348 0,11258536 ! embryonic camera-type eye development GO:0031076 12 5 0,000 0,01926348 0,11231666 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,01926348 0,11204924 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01926348 0,11178309 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 0,01926348 0,1115182 ! transposition GO:0032196 9 5 0,000 0,01926348 0,11125457 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 0,01926348 0,11099217 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 0,000 0,01926348 0,11073101 ! negative chemotaxis GO:0050919 16 5 0,000 0,01926348 0,11047108 ! positive regulation of histone modification GO:0031058 6 5 0,000 0,01926348 0,11021237 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,01926348 0,10995486 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 0,01926348 0,10969856 ! behavioral response to pain GO:0048266 10 5 0,000 0,01926348 0,10944344 ! clathrin coat assembly GO:0048268 15 5 0,000 0,01926348 0,10918952 ! Notch receptor processing GO:0007220 11 5 0,000 0,01926348 0,10893676 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01926348 0,10868518 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 0,01926348 0,10843475 ! micturition GO:0060073 9 5 0,000 0,01926348 0,10818547 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,01926348 0,10793734 ! copulation GO:0007620 9 5 0,000 0,01926348 0,10769035 ! glial cell fate commitment GO:0021781 14 5 0,000 0,01926348 0,10744448 ! protein maturation by protein folding GO:0022417 14 5 0,000 0,01926348 0,10719973 ! bioluminescence GO:0008218 9 5 0,000 0,01926348 0,10695609 ! spermidine metabolic process GO:0008216 7 5 0,000 0,01926348 0,10671356 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,01926348 0,10647213 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,01926348 0,10623179 ! apoptotic cell clearance GO:0043277 23 5 0,000 0,01926348 0,10599252 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,01926348 0,10575434 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 0,01926348 0,10551722 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,01926348 0,10528117 ! grooming behavior GO:0007625 6 5 0,000 0,01926348 0,10504616 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 0,01926348 0,10481221 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,01926348 0,10457929 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 0,01926348 0,10434741 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01926348 0,10411655 ! response to protozoan GO:0001562 13 5 0,000 0,01926348 0,10388671 ! lymph vessel development GO:0001945 10 5 0,000 0,01926348 0,10365789 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 0,01926348 0,10343007 ! endochondral ossification GO:0001958 17 5 0,000 0,01926348 0,10320325 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,01926348 0,10297742 ! single strand break repair GO:0000012 8 5 0,000 0,01926348 0,10275258 ! parathyroid gland development GO:0060017 14 5 0,000 0,01926348 0,10252872 ! anagen GO:0042640 7 5 0,000 0,01926348 0,10230583 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,01926348 0,10208391 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,01926348 0,10186295 ! cytokine secretion GO:0050663 15 5 0,000 0,01926348 0,10164294 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 0,01926348 0,10142388 ! ceramide catabolic process GO:0046514 7 5 0,000 0,01926348 0,10120577 ! smooth muscle tissue development GO:0048745 32 5 0,000 0,01926348 0,10098859 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,01926348 0,10077234 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,01926348 0,10055701 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,01926348 0,1003426 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,01926348 0,10012911 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 9 5 0,000 0,01926348 0,09991652 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,01926348 0,09970483 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 0,01926348 0,09949404 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,01926348 0,09928414 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 0,01926348 0,09907512 ! glycine biosynthetic process GO:0006545 7 5 0,000 0,01926348 0,09886698 ! valine metabolic process GO:0006573 12 5 0,000 0,01926348 0,09865971 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 0,01926348 0,09845331 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 0,01926348 0,09824777 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 0,01926348 0,09804309 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 0,01926348 0,09783925 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 0,01926348 0,09763627 ! polyol biosynthetic process GO:0046173 6 5 0,000 0,01926348 0,09743412 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 0,01926348 0,09723281 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 0,01926348 0,09703233 ! muscle cell migration GO:0014812 8 5 0,000 0,01926348 0,09683268 ! mitochondrial fission GO:0000266 8 5 0,000 0,01926348 0,09663384 ! sister chromatid cohesion GO:0007062 15 5 0,000 0,01926348 0,09643582 ! response to tumor necrosis factor GO:0034612 10 5 0,000 0,01926348 0,09623861 ! mRNA transcription GO:0009299 10 5 0,000 0,01926348 0,09604221 ! nerve growth factor processing GO:0032455 9 5 0,000 0,01926348 0,0958466 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 0,01926348 0,09565179 ! anaerobic glycolysis GO:0019642 6 5 0,000 0,01926348 0,09545777 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,01926348 0,09526454 ! monocyte activation GO:0042117 10 5 0,000 0,01926348 0,09507208 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,01926348 0,09488041 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,01926348 0,0946895 ! response to food GO:0032094 6 5 0,000 0,01926348 0,09449936 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,01926348 0,09430998 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 0,01926348 0,09412136 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01926348 0,0939335 ! forebrain neuron development GO:0021884 13 5 0,000 0,01926348 0,09374638 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,01926348 0,09356 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 0,01926348 0,09337437 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 0,01926348 0,09318947 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,01926348 0,0930053 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01926348 0,09282186 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 0,01926348 0,09263914 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,01926348 0,09245713 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 0,01926348 0,09227585 ! lipid glycosylation GO:0030259 7 5 0,000 0,01926348 0,09209527 ! nucleobase transport GO:0015851 6 5 0,000 0,01926348 0,09191539 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01926348 0,09173622 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 0,01926348 0,09155775 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 0,01926348 0,09137996 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 0,01926348 0,09120287 ! basic amino acid transport GO:0015802 12 5 0,000 0,01926348 0,09102646 ! cellular glucose homeostasis GO:0001678 6 5 0,000 0,01926348 0,09085074 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 0,01926348 0,09067569 ! actin nucleation GO:0045010 11 5 0,000 0,01926348 0,09050131 ! depurination GO:0045007 5 5 0,000 0,01926348 0,0903276 ! depyrimidination GO:0045008 10 5 0,000 0,01926348 0,09015456 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,01926348 0,08998218 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01926348 0,08981046 ! G2/M transition checkpoint GO:0031576 8 5 0,000 0,01926348 0,08963939 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,01926348 0,08946898 ! zinc ion homeostasis GO:0055069 9 5 0,000 0,01926348 0,0892992 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 10 5 0,000 0,01926348 0,08913008 ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 0,01926348 0,08896159 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01926348 0,08879374 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,01926348 0,08862652 ! activated T cell proliferation GO:0050798 16 5 0,000 0,01926348 0,08845993 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,01926348 0,08829396 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 0,01926348 0,08812862 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,01926348 0,08796389 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01926348 0,08779978 ! gamma-delta T cell activation GO:0046629 6 5 0,000 0,01926348 0,08763628 ! response to arsenic GO:0046685 11 5 0,000 0,01926348 0,08747338 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 0,01926348 0,0873111 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,01926348 0,08714941 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 0,01926348 0,08698832 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 0,01926348 0,08682782 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 0,01926348 0,08666792 ! response to mercury ion GO:0046689 8 5 0,000 0,01926348 0,0865086 ! response to cadmium ion GO:0046686 7 5 0,000 0,01926348 0,08634987 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 0,01926348 0,08619172 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 0,01926348 0,08603415 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 0,01926348 0,08587716 ! bile acid biosynthetic process GO:0006699 7 5 0,000 0,01926348 0,08572073 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 0,01926348 0,08556487 ! ganglioside catabolic process GO:0006689 12 5 0,000 0,01926348 0,08540958 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,01926348 0,08525486 ! decidualization GO:0046697 11 5 0,000 0,01926348 0,08510069 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 0,01926348 0,08494708 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 0,01926348 0,08479402 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 0,01926348 0,08464151 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 0,01926348 0,08448955 ! embryonic cleavage GO:0040016 6 5 0,000 0,01926348 0,08433814 ! peroxisome fission GO:0016559 5 5 0,000 0,01926348 0,08418726 ! histone demethylation GO:0016577 13 5 0,000 0,01926348 0,08403693 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 0,01926348 0,08388713 ! mitotic recombination GO:0006312 9 5 0,000 0,01926348 0,08373787 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 0,01926348 0,08358913 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,01926348 0,08344092 ! metaphase plate congression GO:0051310 7 5 0,000 0,01926348 0,08329324 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01926348 0,08314608 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,01926348 0,08299944 ! enteric nervous system development GO:0048484 8 5 0,000 0,01926348 0,08285331 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 0,01926348 0,0827077 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 0,01926348 0,0825626 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 0,01926348 0,08241801 ! muscle cell proliferation GO:0033002 12 5 0,000 0,01926348 0,08227392 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,01926348 0,08213033 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 0,01926348 0,08198725 ! B cell homeostasis GO:0001782 13 5 0,000 0,01926348 0,08184466 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 0,01926348 0,08170257 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,01926348 0,08156097 ! metaphase GO:0051323 11 5 0,000 0,01926348 0,08141986 ! melatonin biosynthetic process GO:0030187 7 5 0,000 0,01926348 0,08127924 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 0,01926348 0,08113911 ! cellular response to nutrient GO:0031670 8 5 0,000 0,01926348 0,08099945 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,01926348 0,08086028 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 0,01926348 0,08072158 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 0,01926348 0,08058336 ! regulation of hair follicle development GO:0051797 10 5 0,000 0,01926348 0,08044561 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 0,01926348 0,08030833 ! response to redox state GO:0051775 6 5 0,000 0,01926348 0,08017152 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 0,01926348 0,08003517 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 0,01926348 0,07989929 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,01926348 0,07976387 ! brown fat cell differentiation GO:0050873 7 5 0,000 0,01926348 0,0796289 ! regulation of telomerase activity GO:0051972 7 5 0,000 0,01926348 0,07949439 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01926348 0,07936034 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 0,01926348 0,07922674 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01926348 0,07909358 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 0,01926348 0,07896087 ! striatum development GO:0021756 14 5 0,000 0,01926348 0,07882861 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 0,01926348 0,07869679 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,01926348 0,07856541 ! glial cell migration GO:0008347 10 5 0,000 0,01926348 0,07843447 ! neural plate morphogenesis GO:0001839 7 5 0,000 0,01926348 0,07830396 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 0,01926348 0,07817389 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,01926348 0,07804425 ! T cell activation during immune response GO:0002286 9 5 0,000 0,01926348 0,07791503 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,01926348 0,07778625 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,01926348 0,07765789 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 0,01926348 0,07752995 ! neuroprotection GO:0043526 8 5 0,000 0,01926348 0,07740244 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,01926348 0,07727534 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,01926348 0,07714866 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 0,01926348 0,07702239 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 0,01926348 0,07689654 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,01926348 0,07677109 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 0,01926348 0,07664606 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,01926348 0,07652143 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 0,01926348 0,07639721 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 0,01926348 0,07627339 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,01926348 0,07614997 ! spindle assembly GO:0051225 6 5 0,000 0,01926348 0,07602695 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,01926348 0,07590432 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,01926348 0,0757821 ! protein palmitoylation GO:0018345 12 5 0,000 0,01926348 0,07566026 ! drug metabolic process GO:0017144 7 5 0,000 0,01926348 0,07553881 ! stem cell division GO:0017145 11 5 0,000 0,01926348 0,07541776 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,01926348 0,07529709 ! organ regeneration GO:0031100 7 5 0,000 0,01926348 0,07517681 ! carnitine metabolic process GO:0009437 8 5 0,000 0,01926348 0,07505691 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,01926348 0,07493739 ! positive regulation of phospholipase activity GO:0010518 111 55 1,000 0,01943012 0,07546547 ! cell recognition GO:0008037 98 55 1,000 0,01943012 0,07534569 ! cell maturation GO:0048469 107 55 1,000 0,01943012 0,07522628 ! negative regulation of cell motion GO:0051271 142 55 1,000 0,01943012 0,07510725 ! skeletal muscle fiber development GO:0048741 130 56 1,000 0,02009918 0,07757077 ! negative regulation of cytoskeleton organization GO:0051494 139 56 1,000 0,02009918 0,07744841 ! regulation of protein catabolic process GO:0042176 126 56 1,000 0,02009918 0,07732645 ! regulation of bone remodeling GO:0046850 143 57 1,000 0,02077779 0,07981155 ! muscle fiber development GO:0048747 131 57 1,000 0,02077779 0,07968626 ! regulation of phospholipase activity GO:0010517 113 57 1,000 0,02077779 0,07956136 ! heart morphogenesis GO:0003007 105 57 1,000 0,02077779 0,07943685 ! nucleotide-excision repair GO:0006289 91 57 1,000 0,02077779 0,07931273 ! aging GO:0007568 112 58 1,000 0,02146588 0,08181145 ! regulation of tissue remodeling GO:0034103 146 58 1,000 0,02146588 0,08168402 ! positive regulation of lipase activity GO:0060193 115 58 1,000 0,02146588 0,08155698 ! lipid modification GO:0030258 112 60 1,000 0,02287013 0,08675734 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,02307174 0,08738644 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,02307174 0,08725116 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 0,02307174 0,08711631 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 0,02307174 0,08698187 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,02307174 0,08684785 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 0,02307174 0,08671423 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 0,02307174 0,08658103 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,02307174 0,08644824 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 0,02307174 0,08631585 ! response to oxygen radical GO:0000305 11 6 0,000 0,02307174 0,08618387 ! positive regulation of axon extension GO:0045773 13 6 0,000 0,02307174 0,08605229 ! myoblast cell fate commitment GO:0048625 18 6 0,000 0,02307174 0,08592112 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 0,02307174 0,08579034 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 0,02307174 0,08565996 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,02307174 0,08552997 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,02307174 0,08540038 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 0,02307174 0,08527118 ! forebrain regionalization GO:0021871 9 6 0,000 0,02307174 0,08514238 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,02307174 0,08501396 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,02307174 0,08488592 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 0,02307174 0,08475827 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,02307174 0,08463101 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 0,02307174 0,08450413 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 0,02307174 0,08437762 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,02307174 0,0842515 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 0,02307174 0,08412575 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 0,02307174 0,08400038 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,02307174 0,08387538 ! malate metabolic process GO:0006108 13 6 0,000 0,02307174 0,08375075 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 0,02307174 0,08362649 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 0,02307174 0,0835026 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 0,02307174 0,08337907 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 0,02307174 0,08325591 ! protein refolding GO:0042026 15 6 0,000 0,02307174 0,08313312 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,02307174 0,08301068 ! opsonization GO:0008228 8 6 0,000 0,02307174 0,08288861 ! mating behavior GO:0007617 7 6 0,000 0,02307174 0,08276689 ! erythrocyte maturation GO:0043249 8 6 0,000 0,02307174 0,08264553 ! embryonic hemopoiesis GO:0035162 16 6 0,000 0,02307174 0,08252453 ! protein amino acid dealkylation GO:0008214 15 6 0,000 0,02307174 0,08240388 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 0,02307174 0,08228358 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 0,02307174 0,08216363 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,02307174 0,08204404 ! response to interferon-gamma GO:0034341 16 6 0,000 0,02307174 0,08192479 ! toxin metabolic process GO:0009404 11 6 0,000 0,02307174 0,08180588 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,02307174 0,08168732 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 0,02307174 0,08156911 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 0,02307174 0,08145123 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 0,02307174 0,0813337 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 13 6 0,000 0,02307174 0,0812165 ! cGMP-mediated signaling GO:0019934 14 6 0,000 0,02307174 0,08109964 ! dorsal spinal cord development GO:0021516 10 6 0,000 0,02307174 0,08098312 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 0,02307174 0,08086693 ! thymic T cell selection GO:0045061 16 6 0,000 0,02307174 0,08075108 ! sphingoid catabolic process GO:0046521 8 6 0,000 0,02307174 0,08063555 ! protein lipoylation GO:0009249 10 6 0,000 0,02307174 0,08052036 ! transepithelial chloride transport GO:0030321 12 6 0,000 0,02307174 0,0804055 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 0,02307174 0,08029096 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,02307174 0,08017675 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 0,02307174 0,08006286 ! glutamate catabolic process GO:0006538 12 6 0,000 0,02307174 0,07994929 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 0,02307174 0,07983605 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,02307174 0,07972313 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 0,02307174 0,07961053 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,02307174 0,07949824 ! hyperosmotic response GO:0006972 10 6 0,000 0,02307174 0,07938627 ! L-serine biosynthetic process GO:0006564 7 6 0,000 0,02307174 0,07927462 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 0,02307174 0,07916328 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 0,02307174 0,07905225 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,02307174 0,07894153 ! urea metabolic process GO:0019627 7 6 0,000 0,02307174 0,07883112 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,02307174 0,07872102 ! neutrophil activation GO:0042119 7 6 0,000 0,02307174 0,07861123 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,02307174 0,07850174 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 0,02307174 0,07839256 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,02307174 0,07828368 ! paraxial mesoderm development GO:0048339 16 6 0,000 0,02307174 0,07817511 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 0,02307174 0,07806683 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,02307174 0,07795886 ! neuron apoptosis GO:0051402 15 6 0,000 0,02307174 0,07785118 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,02307174 0,0777438 ! T cell mediated immunity GO:0002456 17 6 0,000 0,02307174 0,07763671 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,02307174 0,07752992 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 0,02307174 0,07742342 ! carnitine transport GO:0015879 10 6 0,000 0,02307174 0,07731722 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,02307174 0,0772113 ! positive regulation of exocytosis GO:0045921 11 6 0,000 0,02307174 0,07710568 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 0,02307174 0,07700034 ! early endosome to late endosome transport GO:0045022 16 6 0,000 0,02307174 0,0768953 ! 5S class rRNA transcription GO:0042791 13 6 0,000 0,02307174 0,07679053 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! neuronal ion channel clustering GO:0045161 15 6 0,000 0,02307174 0,07668606 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 0,02307174 0,07658186 ! sodium ion homeostasis GO:0055078 12 6 0,000 0,02307174 0,07647795 ! establishment of spindle localization GO:0051293 16 6 0,000 0,02307174 0,07637433 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 0,02307174 0,07627098 ! astrocyte development GO:0014002 16 6 0,000 0,02307174 0,07616791 ! protein targeting to lysosome GO:0006622 12 6 0,000 0,02307174 0,07606512 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,02307174 0,0759626 ! interaction with symbiont GO:0051702 14 6 0,000 0,02307174 0,07586037 ! regulation of dendrite development GO:0050773 16 6 0,000 0,02307174 0,0757584 ! peptidyl-arginine modification GO:0018195 13 6 0,000 0,02307174 0,07565671 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 0,02307174 0,0755553 ! response to copper ion GO:0046688 10 6 0,000 0,02307174 0,07545415 ! response to exogenous dsRNA GO:0043330 13 6 0,000 0,02307174 0,07535328 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 0,02307174 0,07525267 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,02307174 0,07515234 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 0,02307174 0,07505227 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,02307174 0,07495246 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 0,02307174 0,07485292 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,02307174 0,07475365 ! nucleoside catabolic process GO:0009164 10 6 0,000 0,02307174 0,07465464 ! hair follicle maturation GO:0048820 8 6 0,000 0,02307174 0,07455589 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,02307174 0,0744574 ! Schwann cell development GO:0014044 15 6 0,000 0,02307174 0,07435917 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 0,02307174 0,0742612 ! response to pheromone GO:0019236 6 6 0,000 0,02307174 0,07416349 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 0,02307174 0,07406603 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 0,02307174 0,07396884 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 0,02307174 0,07387189 ! base conversion or substitution editing GO:0016553 6 6 0,000 0,02307174 0,0737752 ! subpallium development GO:0021544 15 6 0,000 0,02307174 0,07367876 ! neural tube patterning GO:0021532 8 6 0,000 0,02307174 0,07358258 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 0,02307174 0,07348664 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 0,02307174 0,07339095 ! maintenance of organ identity GO:0048496 9 6 0,000 0,02307174 0,07329552 ! G2 phase GO:0051319 16 6 0,000 0,02307174 0,07320033 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 0,02307174 0,07310539 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 0,02307174 0,07301069 ! oxygen homeostasis GO:0032364 10 6 0,000 0,02307174 0,07291624 ! establishment of planar polarity GO:0001736 7 6 0,000 0,02307174 0,07282203 ! regulation of mast cell activation GO:0033003 13 6 0,000 0,02307174 0,07272807 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,02307174 0,07263435 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 0,02307174 0,07254087 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,02307174 0,07244763 ! receptor internalization GO:0031623 11 6 0,000 0,02307174 0,07235462 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 0,02307174 0,07226186 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 0,02307174 0,07216934 ! neutrophil homeostasis GO:0001780 11 6 0,000 0,02307174 0,07207705 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,02307174 0,071985 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 0,02307174 0,07189318 ! protein deubiquitination GO:0016579 16 6 0,000 0,02307174 0,0718016 ! negative regulation of neuroblast proliferation GO:0007406 25 6 0,000 0,02307174 0,07171024 ! protein destabilization GO:0031648 9 6 0,000 0,02307174 0,07161913 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 0,02307174 0,07152824 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,02307174 0,07143758 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 0,02307174 0,07134716 ! regulation of viral transcription GO:0046782 11 6 0,000 0,02307174 0,07125696 ! progesterone metabolic process GO:0042448 12 6 0,000 0,02307174 0,07116699 ! negative regulation of axon extension GO:0030517 24 6 0,000 0,02307174 0,07107724 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 0,02307174 0,07098772 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 0,02307174 0,07089843 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,02307174 0,07080936 ! determination of adult lifespan GO:0008340 17 6 0,000 0,02307174 0,07072052 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 0,02307174 0,0706319 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 0,02307174 0,07054349 ! neural plate development GO:0001840 9 6 0,000 0,02307174 0,07045532 ! catecholamine transport GO:0051937 9 6 0,000 0,02307174 0,07036736 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 0,02307174 0,07027962 ! sensory cilium assembly GO:0035058 10 6 0,000 0,02307174 0,0701921 ! organ or tissue specific immune response GO:0002251 8 6 0,000 0,02307174 0,07010479 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 0,02307174 0,0700177 ! maternal placenta development GO:0001893 12 6 0,000 0,02307174 0,06993083 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 0,02307174 0,06984418 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,02307174 0,06975774 ! negative regulation of B cell activation GO:0050869 14 6 0,000 0,02307174 0,06967151 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 0,02307174 0,0695855 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 0,02307174 0,06949969 ! positive regulation of coagulation GO:0050820 13 6 0,000 0,02307174 0,0694141 ! cellular anion homeostasis GO:0030002 11 6 0,000 0,02307174 0,06932872 GO:0055081|anion homeostasis, ! cytokine-mediated signaling pathway GO:0019221 112 61 1,000 0,02358613 0,07078738 ! viral reproductive process GO:0022415 132 62 1,000 0,02431128 0,07287418 ! DNA damage response, signal transduction GO:0042770 136 62 1,000 0,02431128 0,07278488 ! regulation of homeostatic process GO:0032844 148 62 1,000 0,02431128 0,07269579 ! tRNA transcription GO:0009304 17 7 0,000 0,02686531 0,08023467 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 0,02686531 0,0801367 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 0,02686531 0,08003897 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,02686531 0,07994148 ! regulation of helicase activity GO:0051095 16 7 0,000 0,02686531 0,07984423 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,02686531 0,07974722 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 0,02686531 0,07965043 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,02686531 0,07955389 ! prostate gland development GO:0030850 14 7 0,000 0,02686531 0,07945758 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,02686531 0,0793615 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,02686531 0,07926565 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,02686531 0,07917003 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,02686531 0,07907465 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,02686531 0,07897949 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,02686531 0,07888457 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,02686531 0,07878987 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! SMAD protein complex assembly GO:0007183 13 7 0,000 0,02686531 0,07869539 ! glycolipid transport GO:0046836 11 7 0,000 0,02686531 0,07860115 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,02686531 0,07850713 GO:0051923|sulfation, ! neuron adhesion GO:0007158 14 7 0,000 0,02686531 0,07841333 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,02686531 0,07831976 ! establishment of tissue polarity GO:0007164 8 7 0,000 0,02686531 0,07822641 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 0,02686531 0,07813328 ! pericardium development GO:0060039 16 7 0,000 0,02686531 0,07804038 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 0,02686531 0,07794769 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 0,02686531 0,07785523 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 0,02686531 0,07776298 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 0,02686531 0,07767096 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,02686531 0,07757915 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,02686531 0,07748755 ! lipoprotein transport GO:0042953 14 7 0,000 0,02686531 0,07739618 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,02686531 0,07730502 ! rhythmic behavior GO:0007622 17 7 0,000 0,02686531 0,07721407 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 0,02686531 0,07712334 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 0,02686531 0,07703282 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,02686531 0,07694251 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 0,02686531 0,07685241 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,02686531 0,07676252 ! regulation of odontogenesis GO:0042481 14 7 0,000 0,02686531 0,07667285 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,02686531 0,07658338 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 0,02686531 0,07649412 ! mechanosensory behavior GO:0007638 16 7 0,000 0,02686531 0,07640507 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 0,02686531 0,07631623 ! positive regulation of isotype switching GO:0045830 17 7 0,000 0,02686531 0,07622759 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 0,02686531 0,07613916 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,02686531 0,07605094 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,02686531 0,07596291 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,02686531 0,0758751 ! spinal cord patterning GO:0021511 14 7 0,000 0,02686531 0,07578748 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 0,02686531 0,07570007 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,02686531 0,07561286 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,02686531 0,07552584 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 0,02686531 0,07543903 ! adrenal gland development GO:0030325 17 7 0,000 0,02686531 0,07535242 ! cysteine metabolic process GO:0006534 13 7 0,000 0,02686531 0,07526601 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 0,02686531 0,07517979 ! ovulation GO:0030728 10 7 0,000 0,02686531 0,07509377 ! adenohypophysis development GO:0021984 11 7 0,000 0,02686531 0,07500795 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 0,02686531 0,07492233 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 0,02686531 0,0748369 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 0,02686531 0,07475166 ! microtubule nucleation GO:0007020 21 7 0,000 0,02686531 0,07466662 ! proline biosynthetic process GO:0006561 10 7 0,000 0,02686531 0,07458177 ! tryptophan metabolic process GO:0006568 11 7 0,000 0,02686531 0,07449712 ! thyroid hormone generation GO:0006590 13 7 0,000 0,02686531 0,07441265 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 0,02686531 0,07432838 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,02686531 0,0742443 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,02686531 0,0741604 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,02686531 0,0740767 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,02686531 0,07399319 ! galactose metabolic process GO:0006012 13 7 0,000 0,02686531 0,07390986 ! vesicle fusion GO:0006906 20 7 0,000 0,02686531 0,07382672 ! response to dietary excess GO:0002021 8 7 0,000 0,02686531 0,07374377 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,02686531 0,07366101 ! intracellular pH reduction GO:0051452 13 7 0,000 0,02686531 0,07357843 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,02686531 0,07349603 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 0,02686531 0,07341382 ! organ growth GO:0035265 15 7 0,000 0,02686531 0,0733318 ! nucleoside transport GO:0015858 11 7 0,000 0,02686531 0,07324995 ! nucleoside salvage GO:0043174 11 7 0,000 0,02686531 0,07316829 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 0,02686531 0,07308681 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,02686531 0,07300552 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 0,02686531 0,0729244 ! parturition GO:0007567 16 7 0,000 0,02686531 0,07284346 ! rRNA modification GO:0000154 14 7 0,000 0,02686531 0,0727627 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,02686531 0,07268212 ! spindle checkpoint GO:0031577 16 7 0,000 0,02686531 0,07260172 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 0,02686531 0,0725215 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,02686531 0,07244146 ! monocyte differentiation GO:0030224 16 7 0,000 0,02686531 0,07236159 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,02686531 0,07228189 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,02686531 0,07220237 GO:0046676|negative regulation of insulin secretion, ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,02686531 0,07212303 ! G1 DNA damage checkpoint GO:0031571 20 7 0,000 0,02686531 0,07204386 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,02686531 0,07196487 ! fibrinolysis GO:0042730 11 7 0,000 0,02686531 0,07188604 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,02686531 0,07180739 ! eating behavior GO:0042755 8 7 0,000 0,02686531 0,07172892 ! B cell lineage commitment GO:0002326 21 7 0,000 0,02686531 0,07165061 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,02686531 0,07157247 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 0,02686531 0,07149451 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 0,02686531 0,07141671 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,02686531 0,07133909 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 0,02686531 0,07126163 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,02686531 0,07118434 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 0,02686531 0,07110721 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 0,02686531 0,07103026 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 0,02686531 0,07095347 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,02686531 0,07087684 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 0,02686531 0,07080039 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,02686531 0,07072409 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,02686531 0,07064796 ! histone ubiquitination GO:0016574 9 7 0,000 0,02686531 0,070572 ! regulation of meiosis GO:0040020 12 7 0,000 0,02686531 0,0704962 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 0,02686531 0,07042056 ! T cell lineage commitment GO:0002360 16 7 0,000 0,02686531 0,07034508 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 0,02686531 0,07026976 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,02686531 0,07019461 ! membrane to membrane docking GO:0022614 14 7 0,000 0,02686531 0,07011961 ! transcription termination GO:0006353 14 7 0,000 0,02686531 0,07004478 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,02686531 0,0699701 ! anaphase GO:0051322 18 7 0,000 0,02686531 0,06989559 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 0,02686531 0,06982123 ! axonal fasciculation GO:0007413 19 7 0,000 0,02686531 0,06974703 ! negative regulation of nuclear division GO:0051784 15 7 0,000 0,02686531 0,06967299 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 0,02686531 0,06959911 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,02686531 0,06952538 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 0,02686531 0,06945181 ! diuresis GO:0030146 12 7 0,000 0,02686531 0,06937839 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,02686531 0,06930513 ! thiamin metabolic process GO:0006772 7 7 0,000 0,02686531 0,06923202 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,02686531 0,06915907 ! antibiotic transport GO:0042891 9 7 0,000 0,02686531 0,06908627 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,02686531 0,06901363 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 0,02686531 0,06894113 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 0,02686531 0,06886879 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 0,02686531 0,0687966 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,02686531 0,06872456 ! melanin biosynthetic process GO:0042438 10 7 0,000 0,02686531 0,06865268 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 0,02686531 0,06858094 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,02686531 0,06850935 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,02686531 0,06843791 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 0,02686531 0,06836662 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,02686531 0,06829548 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 0,02686531 0,06822449 ! endosome to lysosome transport GO:0008333 12 7 0,000 0,02686531 0,06815364 ! protein modification by small protein removal GO:0070646 19 7 0,000 0,02686531 0,06808294 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 0,02686531 0,06801239 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,02686531 0,06794199 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 0,02686531 0,06787173 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,02686531 0,06780161 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,02686531 0,06773164 ! muscle adaptation GO:0043500 13 7 0,000 0,02686531 0,06766181 ! embryonic heart tube development GO:0035050 14 7 0,000 0,02686531 0,06759213 ! retina homeostasis GO:0001895 12 7 0,000 0,02686531 0,06752259 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 0,02686531 0,06745319 ! protein amino acid prenylation GO:0018346 19 7 0,000 0,02686531 0,06738394 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 0,02686531 0,06731483 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 0,02686531 0,06724586 ! regulation of lipid metabolic process GO:0019216 132 66 1,000 0,0273017 0,06826821 ! gonad development GO:0008406 115 66 1,000 0,0273017 0,06819841 ! negative regulation of cell growth GO:0030308 142 67 1,000 0,02807136 0,07004937 ! activation of MAPK activity GO:0000187 124 67 1,000 0,02807136 0,06997789 ! myeloid cell differentiation GO:0030099 126 67 1,000 0,02807136 0,06990655 ! extracellular matrix organization GO:0030198 146 68 1,000 0,02884969 0,07177168 ! viral reproduction GO:0016032 142 68 1,000 0,02884969 0,07169867 ! regulation of lipase activity GO:0060191 137 68 1,000 0,02884969 0,0716258 ! adaptive immune response GO:0002250 126 68 1,000 0,02884969 0,07155308 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! cell projection assembly GO:0030031 138 68 1,000 0,02884969 0,07148052 ! negative regulation of cell size GO:0045792 144 69 1,000 0,02963661 0,07335585 ! developmental maturation GO:0021700 128 69 1,000 0,02963661 0,07328161 ! single fertilization GO:0007338 83 69 1,000 0,02963661 0,07320751 ! germ cell development GO:0007281 133 70 1,000 0,03043204 0,07509643 ! activation of immune response GO:0002253 120 70 1,000 0,03043204 0,07502065 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,03064426 0,07546768 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,03064426 0,07539168 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 0,03064426 0,07531583 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,03064426 0,07524014 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,03064426 0,07516459 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,03064426 0,0750892 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,03064426 0,07501396 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,03064426 0,07493887 ! meiotic prophase I GO:0007128 14 8 0,000 0,03064426 0,07486394 ! response to zinc ion GO:0010043 12 8 0,000 0,03064426 0,07478915 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,03064426 0,07471451 ! oligopeptide transport GO:0006857 16 8 0,000 0,03064426 0,07464002 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,03064426 0,07456567 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,03064426 0,07449148 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,03064426 0,07441743 ! signal peptide processing GO:0006465 12 8 0,000 0,03064426 0,07434353 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,03064426 0,07426978 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,03064426 0,07419617 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,03064426 0,07412271 ! succinate metabolic process GO:0006105 17 8 0,000 0,03064426 0,07404939 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,03064426 0,07397622 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,03064426 0,07390319 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,03064426 0,07383031 ! estrogen metabolic process GO:0008210 17 8 0,000 0,03064426 0,07375757 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,03064426 0,07368498 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,03064426 0,07361252 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,03064426 0,07354021 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,03064426 0,07346804 ! reflex GO:0060004 17 8 0,000 0,03064426 0,07339602 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,03064426 0,07332413 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,03064426 0,07325238 ! hemoglobin metabolic process GO:0020027 14 8 0,000 0,03064426 0,07318078 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,03064426 0,07310931 ! pigment granule organization GO:0048753 17 8 0,000 0,03064426 0,07303799 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,03064426 0,0729668 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,03064426 0,07289575 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,03064426 0,07282484 ! astrocyte differentiation GO:0048708 19 8 0,000 0,03064426 0,07275407 ! histidine catabolic process GO:0006548 10 8 0,000 0,03064426 0,07268343 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,03064426 0,07261294 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,03064426 0,07254257 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,03064426 0,07247235 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,03064426 0,07240226 ! regulation of pigmentation during development GO:0048070 25 8 0,000 0,03064426 0,07233231 ! melanin metabolic process GO:0006582 17 8 0,000 0,03064426 0,07226249 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,03064426 0,0721928 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,03064426 0,07212325 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,03064426 0,07205384 ! macrophage activation GO:0042116 13 8 0,000 0,03064426 0,07198455 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,03064426 0,0719154 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,03064426 0,07184639 ! positive regulation of insulin secretion GO:0032024 17 8 0,000 0,03064426 0,0717775 ! purine salvage GO:0043101 12 8 0,000 0,03064426 0,07170875 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,03064426 0,07164013 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,03064426 0,07157164 ! osteoblast development GO:0002076 17 8 0,000 0,03064426 0,07150328 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,03064426 0,07143505 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,03064426 0,07136696 ! Schwann cell differentiation GO:0014037 21 8 0,000 0,03064426 0,07129899 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,03064426 0,07123115 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,03064426 0,07116344 ! response to UV-B GO:0010224 17 8 0,000 0,03064426 0,07109586 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,03064426 0,0710284 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,03064426 0,07096108 ! intermediate filament organization GO:0045109 12 8 0,000 0,03064426 0,07089388 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,03064426 0,07082681 ! cellular extravasation GO:0045123 13 8 0,000 0,03064426 0,07075986 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,03064426 0,07069305 ! response to antibiotic GO:0046677 11 8 0,000 0,03064426 0,07062635 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,03064426 0,07055979 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,03064426 0,07049335 ! DNA topological change GO:0006265 12 8 0,000 0,03064426 0,07042703 ! response to tropane GO:0014073 15 8 0,000 0,03064426 0,07036084 GO:0042220|response to cocaine, ! melanosome transport GO:0032402 13 8 0,000 0,03064426 0,07029478 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,03064426 0,07022883 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,03064426 0,07016301 ! mast cell activation GO:0045576 14 8 0,000 0,03064426 0,07009732 ! multicellular organismal aging GO:0010259 20 8 0,000 0,03064426 0,07003175 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 0,03064426 0,0699663 ! gas homeostasis GO:0033483 14 8 0,000 0,03064426 0,06990097 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,03064426 0,06983576 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,03064426 0,06977068 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,03064426 0,06970571 ! nucleosome disassembly GO:0006337 14 8 0,000 0,03064426 0,06964087 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,03064426 0,06957615 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 0,03064426 0,06951155 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,03064426 0,06944706 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,03064426 0,0693827 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,03064426 0,06931846 ! intracellular lipid transport GO:0032365 16 8 0,000 0,03064426 0,06925433 ! response to tumor cell GO:0002347 16 8 0,000 0,03064426 0,06919033 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,03064426 0,06912644 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,03064426 0,06906267 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 0,03064426 0,06899902 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,03064426 0,06893548 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 0,03064426 0,06887207 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,03064426 0,06880876 ! hormone catabolic process GO:0042447 17 8 0,000 0,03064426 0,06874558 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,03064426 0,06868251 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,03064426 0,06861956 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,03064426 0,06855672 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,03064426 0,06849399 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,03064426 0,06843139 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,03064426 0,06836889 ! adult feeding behavior GO:0008343 10 8 0,000 0,03064426 0,06830651 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,03064426 0,06824424 ! ATP catabolic process GO:0006200 11 8 0,000 0,03064426 0,06818209 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,03064426 0,06812005 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,03064426 0,06805812 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,03064426 0,06799631 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,03064426 0,06793461 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,03064426 0,06787302 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,03064426 0,06781154 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,03064426 0,06775017 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,03064426 0,06768891 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,03064426 0,06762777 GO:0006043|glucosamine catabolic process, ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,03064426 0,06756673 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 0,03064426 0,0675058 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,03064426 0,06744499 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,03064426 0,06738428 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 0,03064426 0,06732368 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 0,03064426 0,0672632 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,03064426 0,06720282 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 0,03064426 0,06714254 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 0,03064426 0,06708238 ! carbohydrate transport GO:0008643 114 72 1,000 0,03204812 0,07009271 ! actin filament organization GO:0007015 167 72 1,000 0,03204812 0,07003001 ! amino acid transport GO:0006865 148 74 1,000 0,03369733 0,07356799 ! regulation of caspase activity GO:0043281 136 74 1,000 0,03369733 0,0735023 ! axon extension GO:0048675 16 9 0,000 0,03440865 0,07498691 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,03440865 0,07492007 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 0,03440865 0,07485336 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,03440865 0,07478676 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,03440865 0,07472029 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,03440865 0,07465393 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,03440865 0,07458769 ! reproductive behavior GO:0019098 22 9 0,000 0,03440865 0,07452156 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,03440865 0,07445556 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 0,03440865 0,07438967 GO:0010469|regulation of receptor activity, ! UTP metabolic process GO:0046051 10 9 0,000 0,03440865 0,07432389 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,03440865 0,07425824 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,03440865 0,07419269 ! artery development GO:0060840 25 9 0,000 0,03440865 0,07412727 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,03440865 0,07406196 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,03440865 0,07399676 ! equilibrioception GO:0050957 20 9 0,000 0,03440865 0,07393168 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,03440865 0,07386672 ! chemosensory behavior GO:0007635 21 9 0,000 0,03440865 0,07380186 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,03440865 0,07373712 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,03440865 0,0736725 ! leukocyte degranulation GO:0043299 16 9 0,000 0,03440865 0,07360799 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,03440865 0,07354359 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,03440865 0,0734793 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,03440865 0,07341513 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,03440865 0,07335107 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,03440865 0,07328712 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,03440865 0,07322328 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,03440865 0,07315955 ! protein targeting to ER GO:0045047 25 9 0,000 0,03440865 0,07309593 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,03440865 0,07303243 ! T cell selection GO:0045058 27 9 0,000 0,03440865 0,07296903 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,03440865 0,07290574 ! glycine catabolic process GO:0006546 15 9 0,000 0,03440865 0,07284257 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,03440865 0,0727795 ! endosome organization GO:0007032 20 9 0,000 0,03440865 0,07271654 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,03440865 0,07265369 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,03440865 0,07259095 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,03440865 0,07252832 ! mannose metabolic process GO:0006013 13 9 0,000 0,03440865 0,07246579 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,03440865 0,07240338 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,03440865 0,07234107 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,03440865 0,07227887 ! receptor clustering GO:0043113 20 9 0,000 0,03440865 0,07221677 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,03440865 0,07215478 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,03440865 0,0720929 ! retinol metabolic process GO:0042572 20 9 0,000 0,03440865 0,07203112 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,03440865 0,07196945 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,03440865 0,07190789 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,03440865 0,07184643 ! macrophage differentiation GO:0030225 15 9 0,000 0,03440865 0,07178507 ! oligodendrocyte development GO:0014003 11 9 0,000 0,03440865 0,07172382 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 0,03440865 0,07166268 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,03440865 0,07160164 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,03440865 0,0715407 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,03440865 0,07147987 ! establishment of melanosome localization GO:0032401 14 9 0,000 0,03440865 0,07141914 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,03440865 0,07135851 ! erythrocyte development GO:0048821 17 9 0,000 0,03440865 0,07129798 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,03440865 0,07123756 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,03440865 0,07117724 ! renal water homeostasis GO:0003091 15 9 0,000 0,03440865 0,07111702 ! postreplication repair GO:0006301 25 9 0,000 0,03440865 0,07105691 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,03440865 0,07099689 ! icosanoid secretion GO:0032309 15 9 0,000 0,03440865 0,07093698 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,03440865 0,07087717 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,03440865 0,07081746 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,03440865 0,07075785 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,03440865 0,07069834 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,03440865 0,07063893 ! sterol catabolic process GO:0016127 14 9 0,000 0,03440865 0,07057962 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,03440865 0,0705204 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,03440865 0,07046129 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,03440865 0,07040228 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,03440865 0,07034337 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 0,03440865 0,07028455 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,03440865 0,07022583 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 0,03440865 0,07016721 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,03440865 0,07010869 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,03440865 0,07005027 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,03440865 0,06999194 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,03440865 0,06993371 ! purine base metabolic process GO:0006144 25 9 0,000 0,03440865 0,06987558 ! pigment granule transport GO:0051904 17 9 0,000 0,03440865 0,06981754 ! regulation of telomere maintenance GO:0032204 17 9 0,000 0,03440865 0,0697596 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,03440865 0,06970176 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,03440865 0,06964401 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,03440865 0,06958636 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,03440865 0,0695288 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,03440865 0,06947134 ! mitochondrion localization GO:0051646 18 9 0,000 0,03440865 0,06941397 ! regulation of transcription factor activity GO:0051090 137 75 1,000 0,03453417 0,06960972 GO:0090046|regulation of transcription regulator activity, ! reproductive structure development GO:0048608 131 75 1,000 0,03453417 0,06955234 ! phosphoinositide-mediated signaling GO:0048015 141 75 1,000 0,03453417 0,06949504 ! axon guidance GO:0007411 162 75 1,000 0,03453417 0,06943785 ! learning or memory GO:0007611 161 76 1,000 0,03537907 0,07107818 ! regulation of endopeptidase activity GO:0052548 141 77 1,000 0,03623195 0,07273184 ! fertilization GO:0009566 99 78 1,000 0,03709274 0,07439865 ! positive regulation of lymphocyte activation GO:0051251 142 78 1,000 0,03709274 0,07433762 ! response to steroid hormone stimulus GO:0048545 147 79 1,000 0,03796136 0,07601607 ! regulation of synaptic transmission GO:0050804 159 79 1,000 0,03796136 0,07595381 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,03815852 0,0762858 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,03815852 0,07622343 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,03815852 0,07616115 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,03815852 0,07609898 ! associative learning GO:0008306 21 10 0,000 0,03815852 0,07603691 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,03815852 0,07597494 ! phosphate transport GO:0006817 24 10 0,000 0,03815852 0,07591307 ! cell volume homeostasis GO:0006884 17 10 0,000 0,03815852 0,0758513 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,03815852 0,07578964 ! CTP metabolic process GO:0046036 11 10 0,000 0,03815852 0,07572807 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 0,03815852 0,0756666 ! GTP metabolic process GO:0046039 11 10 0,000 0,03815852 0,07560523 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,03815852 0,07554397 GO:0007520|myoblast fusion, ! social behavior GO:0035176 29 10 0,000 0,03815852 0,0754828 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,03815852 0,07542173 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,03815852 0,07536075 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,03815852 0,07529988 ! androgen metabolic process GO:0008209 17 10 0,000 0,03815852 0,07523911 ! phospholipid efflux GO:0033700 19 10 0,000 0,03815852 0,07517843 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,03815852 0,07511785 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,03815852 0,07505737 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,03815852 0,07499699 ! pathogenesis GO:0009405 17 10 0,000 0,03815852 0,0749367 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,03815852 0,07487651 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 0,03815852 0,07481641 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,03815852 0,07475642 ! endoderm development GO:0007492 18 10 0,000 0,03815852 0,07469652 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,03815852 0,07463671 ! arginine catabolic process GO:0006527 17 10 0,000 0,03815852 0,074577 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,03815852 0,07451739 ! proline metabolic process GO:0006560 13 10 0,000 0,03815852 0,07445787 ! phosphagen metabolic process GO:0006599 17 10 0,000 0,03815852 0,07439845 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,03815852 0,07433912 ! V(D)J recombination GO:0033151 34 10 0,000 0,03815852 0,07427988 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,03815852 0,07422074 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,03815852 0,0741617 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,03815852 0,07410274 ! B cell proliferation GO:0042100 19 10 0,000 0,03815852 0,07404389 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,03815852 0,07398512 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,03815852 0,07392645 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,03815852 0,07386787 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,03815852 0,07380938 ! ruffle organization GO:0031529 17 10 0,000 0,03815852 0,07375099 ! epithelial cell development GO:0002064 21 10 0,000 0,03815852 0,07369269 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,03815852 0,07363448 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,03815852 0,07357636 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,03815852 0,07351834 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,03815852 0,0734604 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,03815852 0,07340256 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,03815852 0,07334481 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 13 10 0,000 0,03815852 0,07328715 ! brain morphogenesis GO:0048854 23 10 0,000 0,03815852 0,07322958 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,03815852 0,0731721 ! segment specification GO:0007379 15 10 0,000 0,03815852 0,07311471 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,03815852 0,07305741 ! blastoderm segmentation GO:0007350 19 10 0,000 0,03815852 0,0730002 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,03815852 0,07294308 ! response to dsRNA GO:0043331 23 10 0,000 0,03815852 0,07288605 ! DNA ligation GO:0006266 18 10 0,000 0,03815852 0,0728291 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,03815852 0,07277225 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,03815852 0,07271549 ! melanosome localization GO:0032400 16 10 0,000 0,03815852 0,07265881 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,03815852 0,07260222 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,03815852 0,07254572 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,03815852 0,07248931 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,03815852 0,07243299 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,03815852 0,07237675 ! induction of an organ GO:0001759 17 10 0,000 0,03815852 0,0723206 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,03815852 0,07226454 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,03815852 0,07220856 ! protein sumoylation GO:0016925 17 10 0,000 0,03815852 0,07215267 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,03815852 0,07209687 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,03815852 0,07204115 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,03815852 0,07198552 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,03815852 0,07192998 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,03815852 0,07187452 ! salivary gland development GO:0007431 28 10 0,000 0,03815852 0,07181915 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,03815852 0,07176386 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,03815852 0,07170866 ! midbrain development GO:0030901 14 10 0,000 0,03815852 0,07165354 ! musculoskeletal movement GO:0050881 16 10 0,000 0,03815852 0,0715985 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,03815852 0,07154356 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,03815852 0,07148869 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,03815852 0,07143391 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,03815852 0,07137921 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,03815852 0,0713246 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,03815852 0,07127007 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,03815852 0,07121562 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,03815852 0,07116126 ! detection of calcium ion GO:0005513 24 10 0,000 0,03815852 0,07110698 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,03815852 0,07105278 ! blastocyst formation GO:0001825 18 10 0,000 0,03815852 0,07099867 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,03815852 0,07094464 ! cerebellar cortex development GO:0021695 16 10 0,000 0,03815852 0,07089069 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,03815852 0,07083682 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,03815852 0,07078303 ! response to nicotine GO:0035094 20 10 0,000 0,03815852 0,07072933 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,03815852 0,0706757 ! activation of protein kinase activity GO:0032147 170 80 1,000 0,03883775 0,07187925 ! development of primary sexual characteristics GO:0045137 143 80 1,000 0,03883775 0,07182484 ! negative regulation of organelle organization GO:0010639 181 80 1,000 0,03883775 0,07177051 ! meiosis GO:0007126 143 81 1,000 0,03972182 0,07334876 GO:0051327|M phase of meiotic cell cycle, ! muscle cell differentiation GO:0042692 178 81 1,000 0,03972182 0,07329336 ! regulation of peptidase activity GO:0052547 150 82 1,000 0,04061352 0,07488213 ! meiotic cell cycle GO:0051321 144 82 1,000 0,04061352 0,07482566 ! exocytosis GO:0006887 153 83 1,000 0,04151276 0,07642477 ! response to drug GO:0042493 149 83 1,000 0,04151276 0,07636722 ! negative regulation of muscle development GO:0048635 27 11 0,000 0,04189393 0,07701043 ! respiratory burst GO:0045730 17 11 0,000 0,04189393 0,07695253 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,04189393 0,07689471 ! neuron fate specification GO:0048665 18 11 0,000 0,04189393 0,07683699 ! telencephalon cell migration GO:0022029 23 11 0,000 0,04189393 0,07677934 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,04189393 0,07672179 ! thyroid gland development GO:0030878 26 11 0,000 0,04189393 0,07666432 ! synapsis GO:0007129 14 11 0,000 0,04189393 0,07660693 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,04189393 0,07654964 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,04189393 0,07649242 ! response to pain GO:0048265 27 11 0,000 0,04189393 0,0764353 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,04189393 0,07637826 ! keratinocyte proliferation GO:0043616 19 11 0,000 0,04189393 0,0763213 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 0,000 0,04189393 0,07626443 GO:0010812|negative regulation of cell-substrate adhesion, ! bone resorption GO:0045453 16 11 0,000 0,04189393 0,07620764 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,04189393 0,07615094 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,04189393 0,07609432 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,04189393 0,07603779 ! melanocyte differentiation GO:0030318 20 11 0,000 0,04189393 0,07598134 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,04189393 0,07592497 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,04189393 0,07586869 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,04189393 0,07581249 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,04189393 0,07575638 ! regulation of intracellular pH GO:0051453 21 11 0,000 0,04189393 0,07570034 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,04189393 0,07564439 ! UV protection GO:0009650 20 11 0,000 0,04189393 0,07558853 ! adult heart development GO:0007512 16 11 0,000 0,04189393 0,07553274 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,04189393 0,07547704 ! macroautophagy GO:0016236 19 11 0,000 0,04189393 0,07542142 ! temperature homeostasis GO:0001659 18 11 0,000 0,04189393 0,07536588 ! behavioral fear response GO:0001662 27 11 0,000 0,04189393 0,07531042 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,04189393 0,07525505 ! negative regulation of ossification GO:0030279 27 11 0,000 0,04189393 0,07519975 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,04189393 0,07514454 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,04189393 0,07508941 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 0,04189393 0,07503436 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,04189393 0,07497939 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,04189393 0,0749245 ! regulation of organ growth GO:0046620 14 11 0,000 0,04189393 0,07486969 ! pigment granule localization GO:0051875 20 11 0,000 0,04189393 0,07481496 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,04189393 0,07476031 ! vasoconstriction GO:0042310 20 11 0,000 0,04189393 0,07470574 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,04189393 0,07465125 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,04189393 0,07459684 ! embryonic axis specification GO:0000578 19 11 0,000 0,04189393 0,07454251 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,04189393 0,07448826 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,04189393 0,07443408 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,04189393 0,07437999 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,04189393 0,07432597 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,04189393 0,07427203 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,04189393 0,07421818 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,04189393 0,07416439 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,04189393 0,07411069 ! prophase GO:0051324 17 11 0,000 0,04189393 0,07405707 ! nucleosome positioning GO:0016584 15 11 0,000 0,04189393 0,07400352 ! regulation of isotype switching GO:0045191 24 11 0,000 0,04189393 0,07395005 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,04189393 0,07389665 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,04189393 0,07384334 ! apical protein localization GO:0045176 18 11 0,000 0,04189393 0,0737901 ! acid secretion GO:0046717 20 11 0,000 0,04189393 0,07373693 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,04189393 0,07368385 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,04189393 0,07363084 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,04189393 0,0735779 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,04189393 0,07352505 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,04189393 0,07347226 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 0,04189393 0,07341956 ! cholesterol efflux GO:0033344 21 11 0,000 0,04189393 0,07336693 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,04189393 0,07331437 ! germ cell migration GO:0008354 26 11 0,000 0,04189393 0,07326189 ! embryonic gut development GO:0048566 19 11 0,000 0,04189393 0,07320949 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,04189393 0,07315716 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,04189393 0,0731049 ! activation of innate immune response GO:0002218 16 11 0,000 0,04189393 0,07305272 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,04189393 0,07300062 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,04189393 0,07294858 ! lysogeny GO:0030069 22 11 0,000 0,04189393 0,07289663 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,04189393 0,07284474 ! sequestering of metal ion GO:0051238 15 11 0,000 0,04189393 0,07279293 ! nucleus localization GO:0051647 22 11 0,000 0,04189393 0,0727412 ! response to nutrient GO:0007584 135 84 1,000 0,04241947 0,0736014 ! regulation of neuron differentiation GO:0045664 187 85 1,000 0,04333359 0,07513412 ! regulation of transmission of nerve impulse GO:0051969 167 85 1,000 0,04333359 0,07508083 ! negative regulation of growth GO:0045926 168 85 1,000 0,04333359 0,07502762 ! positive regulation of cell activation GO:0050867 161 86 1,000 0,04425505 0,07656876 GO:0002696|positive regulation of leukocyte activation, ! alcohol catabolic process GO:0046164 142 87 1,000 0,04518377 0,07812028 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,04561494 0,07880997 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,04561494 0,07875427 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,04561494 0,07869865 ! mating GO:0007618 17 12 0,000 0,04561494 0,07864311 ! protein complex disassembly GO:0043241 28 12 0,000 0,04561494 0,07858765 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,04561494 0,07853227 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,04561494 0,07847697 ! T cell proliferation GO:0042098 32 12 0,000 0,04561494 0,07842174 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,04561494 0,07836659 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,04561494 0,07831152 ! ventral spinal cord development GO:0021517 25 12 0,000 0,04561494 0,07825652 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,04561494 0,07820161 ! drug transport GO:0015893 16 12 0,000 0,04561494 0,07814677 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,04561494 0,078092 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,04561494 0,07803732 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,04561494 0,07798271 ! polyamine metabolic process GO:0006595 18 12 0,000 0,04561494 0,07792818 ! focal adhesion formation GO:0048041 37 12 0,000 0,04561494 0,07787372 ! mitotic spindle organization GO:0007052 23 12 0,000 0,04561494 0,07781934 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,04561494 0,07776503 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,04561494 0,0777108 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,04561494 0,07765665 ! lipid digestion GO:0044241 21 12 0,000 0,04561494 0,07760257 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,04561494 0,07754857 ! entry into host cell GO:0030260 34 12 0,000 0,04561494 0,07749464 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,04561494 0,07744079 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,04561494 0,07738701 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,04561494 0,0773333 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,04561494 0,07727967 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,04561494 0,07722612 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,04561494 0,07717264 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,04561494 0,07711923 ! snRNA metabolic process GO:0016073 30 12 0,000 0,04561494 0,0770659 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,04561494 0,07701264 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,04561494 0,07695946 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,04561494 0,07690634 ! fucose catabolic process GO:0019317 25 12 0,000 0,04561494 0,0768533 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,04561494 0,07680034 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,04561494 0,07674745 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 0,04561494 0,07669463 ! zymogen activation GO:0031638 18 12 0,000 0,04561494 0,07664188 ! T cell homeostasis GO:0043029 28 12 0,000 0,04561494 0,0765892 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,04561494 0,0765366 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,04561494 0,07648407 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,04561494 0,07643161 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,04561494 0,07637923 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,04561494 0,07632691 ! defense response to fungus GO:0050832 15 12 0,000 0,04561494 0,07627467 ! developmental induction GO:0031128 22 12 0,000 0,04561494 0,0762225 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 21 12 0,000 0,04561494 0,0761704 ! lamellipodium assembly GO:0030032 24 12 0,000 0,04561494 0,07611837 ! response to cold GO:0009409 17 12 0,000 0,04561494 0,07606641 ! establishment of cell polarity GO:0030010 21 12 0,000 0,04561494 0,07601452 ! regulation of synapse organization GO:0050807 18 12 0,000 0,04561494 0,07596271 ! regulation of DNA binding GO:0051101 167 89 1,000 0,04706273 0,07832033 ! regulation of neurological system process GO:0031644 175 89 1,000 0,04706273 0,07826702 ! regulation of cell cycle process GO:0010564 161 90 1,000 0,04801283 0,07979275 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,0493216 0,08191208 ! cGMP metabolic process GO:0046068 18 13 0,000 0,0493216 0,08185643 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,0493216 0,08180086 ! regulation of chemokine production GO:0032642 18 13 0,000 0,0493216 0,08174536 ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,0493216 0,08168994 ! peroxisomal transport GO:0043574 28 13 0,000 0,0493216 0,0816346 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,0493216 0,08157933 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,0493216 0,08152413 ! organelle fusion GO:0048284 36 13 0,000 0,0493216 0,08146901 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,0493216 0,08141396 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,0493216 0,08135899 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,0493216 0,08130409 ! endocrine pancreas development GO:0031018 25 13 0,000 0,0493216 0,08124927 ! positive regulation of cell growth GO:0030307 24 13 0,000 0,0493216 0,08119452 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,0493216 0,08113984 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,0493216 0,08108524 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,0493216 0,08103071 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,0493216 0,08097626 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,0493216 0,08092187 ! methionine metabolic process GO:0006555 31 13 0,000 0,0493216 0,08086756 ! plasma membrane organization GO:0007009 27 13 0,000 0,0493216 0,08081333 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,0493216 0,08075916 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,0493216 0,08070507 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,0493216 0,08065105 ! cytokine metabolic process GO:0042107 24 13 0,000 0,0493216 0,0805971 ! exocrine system development GO:0035272 34 13 0,000 0,0493216 0,08054323 ! asymmetric protein localization GO:0008105 24 13 0,000 0,0493216 0,08048942 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,0493216 0,08043569 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 0,0493216 0,08038203 ! L-glutamate transport GO:0015813 30 13 0,000 0,0493216 0,08032845 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,0493216 0,08027493 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,0493216 0,08022148 ! protein homotetramerization GO:0051289 24 13 0,000 0,0493216 0,08016811 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,0493216 0,08011481 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,0493216 0,08006157 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,0493216 0,08000841 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,0493216 0,07995532 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,0493216 0,0799023 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,0493216 0,07984935 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,0493216 0,07979647 ! histone methylation GO:0016571 29 13 0,000 0,0493216 0,07974366 ! chromatin silencing GO:0006342 29 13 0,000 0,0493216 0,07969092 ! gland morphogenesis GO:0022612 31 13 0,000 0,0493216 0,07963825 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,0493216 0,07958565 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 0,0493216 0,07953311 ! regulation of epidermis development GO:0045682 19 13 0,000 0,0493216 0,07948065 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,0493216 0,07942826 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,0493216 0,07937593 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,0493216 0,07932368 ! spleen development GO:0048536 24 13 0,000 0,0493216 0,07927149 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,0493216 0,07921937 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,0493216 0,07916732 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,0493216 0,07911534 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,0493216 0,07906343 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,0493216 0,07901159 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,0493216 0,07895981 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,0493216 0,0789081 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,0493216 0,07885646 ! insulin secretion GO:0030073 24 13 0,000 0,0493216 0,07880488 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,0493216 0,07875338 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 0,0493216 0,07870194 ! acrosome reaction GO:0007340 19 13 0,000 0,0493216 0,07865057 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,0493216 0,07859926 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,0493216 0,07854802 ! regulation of cell adhesion GO:0030155 241 92 1,000 0,04993393 0,0794714 ! regulation of cell morphogenesis GO:0022604 243 93 1,000 0,0509048 0,08096382 ! amine transport GO:0015837 181 93 1,000 0,0509048 0,08091114 ! negative regulation of multicellular organismal process GO:0051241 174 95 1,000 0,05286683 0,08397508 ! rRNA transcription GO:0009303 28 14 0,000 0,05301397 0,08415408 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,05301397 0,08409943 GO:0046579|positive regulation of Ras protein signal transduction, ! water transport GO:0006833 21 14 0,000 0,05301397 0,08404486 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,05301397 0,08399036 ! non-recombinational repair GO:0000726 29 14 0,000 0,05301397 0,08393592 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,05301397 0,08388156 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,05301397 0,08382727 ! hair follicle morphogenesis GO:0031069 27 14 0,000 0,05301397 0,08377305 ! RNA polyadenylation GO:0043631 32 14 0,000 0,05301397 0,08371889 ! lipid localization GO:0010876 32 14 0,000 0,05301397 0,08366481 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 0,05301397 0,0836108 ! regulated secretory pathway GO:0045055 24 14 0,000 0,05301397 0,08355686 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,05301397 0,08350298 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,05301397 0,08344918 ! arginine metabolic process GO:0006525 21 14 0,000 0,05301397 0,08339545 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,05301397 0,08334178 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,05301397 0,08328819 ! regulation of heart rate GO:0002027 25 14 0,000 0,05301397 0,08323466 ! fear response GO:0042596 34 14 0,000 0,05301397 0,0831812 ! organic alcohol transport GO:0015850 29 14 0,000 0,05301397 0,08312781 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,05301397 0,08307449 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 0,000 0,05301397 0,08302124 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,05301397 0,08296805 ! neutral amino acid transport GO:0015804 28 14 0,000 0,05301397 0,08291494 ! bone mineralization GO:0030282 18 14 0,000 0,05301397 0,08286189 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,05301397 0,08280891 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,05301397 0,08275599 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,05301397 0,08270315 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,05301397 0,08265037 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,05301397 0,08259766 ! regulation of cellular pH GO:0030641 27 14 0,000 0,05301397 0,08254502 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,05301397 0,08249244 ! ribosome assembly GO:0042255 18 14 0,000 0,05301397 0,08243993 ! cerebellum development GO:0021549 23 14 0,000 0,05301397 0,08238749 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,05301397 0,08233511 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,05301397 0,0822828 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,05301397 0,08223056 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,05301397 0,08217838 ! NADP metabolic process GO:0006739 24 14 0,000 0,05301397 0,08212627 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,05301397 0,08207423 ! oxygen transport GO:0015671 22 14 0,000 0,05301397 0,08202225 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,05301397 0,08197033 ! male genitalia development GO:0030539 26 14 0,000 0,05301397 0,08191849 ! regulation of axon extension GO:0030516 43 14 0,000 0,05301397 0,08186671 ! release of cytochrome c from mitochondria GO:0001836 31 14 0,000 0,05301397 0,08181499 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,05301397 0,08176334 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 0,05301397 0,08171175 ! regulation of T cell activation GO:0050863 175 96 1,000 0,05385786 0,08296013 ! biogenic amine metabolic process GO:0006576 162 97 1,000 0,05485548 0,08444357 ! forebrain development GO:0030900 210 98 1,000 0,05585963 0,08593519 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,0566921 0,08716099 ! lactation GO:0007595 30 15 0,000 0,0566921 0,08710617 ! reproductive cellular process GO:0048610 22 15 0,000 0,0566921 0,08705142 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,0566921 0,08699674 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,0566921 0,08694213 ! superoxide anion generation GO:0042554 22 15 0,000 0,0566921 0,08688758 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,0566921 0,08683311 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,0566921 0,0867787 ! copper ion transport GO:0006825 22 15 0,000 0,0566921 0,08672436 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,0566921 0,08667009 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,0566921 0,08661589 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,0566921 0,08656176 ! sulfate transport GO:0008272 27 15 0,000 0,0566921 0,08650769 ! response to cAMP GO:0051591 25 15 0,000 0,0566921 0,08645369 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,0566921 0,08639976 ! regulation of mRNA processing GO:0050684 26 15 0,000 0,0566921 0,08634589 ! response to hexose stimulus GO:0009746 25 15 0,000 0,0566921 0,08629209 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,0566921 0,08623836 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,0566921 0,0861847 ! vesicle coating GO:0006901 38 15 0,000 0,0566921 0,0861311 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 0,000 0,0566921 0,08607757 ! regulation of exocytosis GO:0017157 26 15 0,000 0,0566921 0,0860241 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,0566921 0,08597071 ! G1/S transition checkpoint GO:0031575 37 15 0,000 0,0566921 0,08591738 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,0566921 0,08586411 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,0566921 0,08581091 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,0566921 0,08575778 ! regulation of vasodilation GO:0042312 27 15 0,000 0,0566921 0,08570471 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,0566921 0,08565171 ! histone deacetylation GO:0016575 24 15 0,000 0,0566921 0,08559877 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,0566921 0,0855459 ! water homeostasis GO:0030104 28 15 0,000 0,0566921 0,08549309 ! cofactor transport GO:0051181 30 15 0,000 0,0566921 0,08544035 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,0566921 0,08538767 ! muscle maintenance GO:0046716 26 15 0,000 0,0566921 0,08533506 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,0566921 0,08528252 ! intestinal absorption GO:0050892 31 15 0,000 0,0566921 0,08523004 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,0566921 0,08517762 ! heme biosynthetic process GO:0006783 33 15 0,000 0,0566921 0,08512527 ! cell killing GO:0001906 32 15 0,000 0,0566921 0,08507298 ! lymphocyte homeostasis GO:0002260 33 15 0,000 0,0566921 0,08502075 ! epithelial to mesenchymal transition GO:0001837 30 15 0,000 0,0566921 0,08496859 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,0566921 0,0849165 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,0566921 0,08486447 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,0566921 0,0848125 ! actin filament polymerization GO:0030041 27 15 0,000 0,0566921 0,08476059 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,0566921 0,08470875 ! positive regulation of immune response GO:0050778 175 100 1,000 0,05788724 0,08644164 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,06035605 0,09007321 ! positive regulation of cell size GO:0045793 29 16 0,000 0,06035605 0,09001822 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,06035605 0,08996329 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,06035605 0,08990844 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,06035605 0,08985365 ! bone remodeling GO:0046849 28 16 0,000 0,06035605 0,08979893 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 0,000 0,06035605 0,08974427 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,06035605 0,08968968 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,06035605 0,08963516 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,06035605 0,0895807 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,06035605 0,08952631 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,06035605 0,08947199 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,06035605 0,08941773 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,06035605 0,08936354 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,06035605 0,08930941 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,06035605 0,08925535 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,06035605 0,08920135 ! protein polyubiquitination GO:0000209 41 16 0,000 0,06035605 0,08914742 ! glutamate metabolic process GO:0006536 25 16 0,000 0,06035605 0,08909356 ! pituitary gland development GO:0021983 30 16 0,000 0,06035605 0,08903976 ! response to osmotic stress GO:0006970 27 16 0,000 0,06035605 0,08898602 ! lysosomal transport GO:0007041 31 16 0,000 0,06035605 0,08893235 ! fructose metabolic process GO:0006000 25 16 0,000 0,06035605 0,08887875 ! L-amino acid transport GO:0015807 33 16 0,000 0,06035605 0,0888252 ! stem cell development GO:0048864 46 16 0,000 0,06035605 0,08877173 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,06035605 0,08871831 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,06035605 0,08866497 ! intermediate filament-based process GO:0045103 36 16 0,000 0,06035605 0,08861168 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,06035605 0,08855846 ! negative regulation of immune response GO:0050777 38 16 0,000 0,06035605 0,08850531 ! axon cargo transport GO:0008088 46 16 0,000 0,06035605 0,08845221 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,06035605 0,08839918 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,06035605 0,08834622 ! DNA replication initiation GO:0006270 28 16 0,000 0,06035605 0,08829332 ! neuron recognition GO:0008038 40 16 0,000 0,06035605 0,08824048 ! mRNA splice site selection GO:0006376 44 16 0,000 0,06035605 0,0881877 ! tissue regeneration GO:0042246 27 16 0,000 0,06035605 0,08813499 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,06035605 0,08808234 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,06035605 0,08802975 ! biomineral formation GO:0031214 22 16 0,000 0,06035605 0,08797723 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,06035605 0,08792477 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,06035605 0,08787237 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,06035605 0,08782004 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,06035605 0,08776776 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,06035605 0,08771555 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,06035605 0,0876634 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,06035605 0,08761131 ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,06035605 0,08755929 ! peptide hormone processing GO:0016486 27 16 0,000 0,06035605 0,08750732 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,06400588 0,09274398 ! metencephalon development GO:0022037 32 17 0,000 0,06400588 0,09268901 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,06400588 0,0926341 ! negative regulation of cell cycle process GO:0010948 35 17 0,000 0,06400588 0,09257925 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,06400588 0,09252447 ! filopodium assembly GO:0046847 42 17 0,000 0,06400588 0,09246975 ! endothelial cell migration GO:0043542 31 17 0,000 0,06400588 0,0924151 ! gene silencing by RNA GO:0031047 38 17 0,000 0,06400588 0,09236052 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,06400588 0,09230599 ! glial cell development GO:0021782 28 17 0,000 0,06400588 0,09225154 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,06400588 0,09219714 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,06400588 0,09214281 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,06400588 0,09208855 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 0,000 0,06400588 0,09203435 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,06400588 0,09198021 ! myoblast differentiation GO:0045445 50 17 0,000 0,06400588 0,09192613 ! regulation of survival gene product expression GO:0045884 38 17 0,000 0,06400588 0,09187212 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,06400588 0,09181818 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,06400588 0,09176429 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,06400588 0,09171047 ! NAD metabolic process GO:0019674 33 17 0,000 0,06400588 0,09165671 ! membrane budding GO:0006900 42 17 0,000 0,06400588 0,09160302 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,06400588 0,09154939 ! regulation of protein binding GO:0043393 33 17 0,000 0,06400588 0,09149582 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,06400588 0,09144231 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,06400588 0,09138887 ! genitalia development GO:0048806 32 17 0,000 0,06400588 0,09133549 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,06400588 0,09128217 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 0,000 0,06400588 0,09122891 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,06400588 0,09117572 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,06400588 0,09112258 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,06400588 0,09106951 ! steroid catabolic process GO:0006706 34 17 0,000 0,06400588 0,0910165 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,06400588 0,09096356 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,06400588 0,09091067 ! gas transport GO:0015669 26 17 0,000 0,06400588 0,09085785 ! organic cation transport GO:0015695 32 17 0,000 0,06400588 0,09080508 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,06400588 0,09075238 ! positive regulation of protein complex assembly GO:0031334 34 18 0,000 0,06764162 0,09585179 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,06764162 0,09579622 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,06764162 0,09574072 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,06764162 0,09568528 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,06764162 0,09562991 ! adult walking behavior GO:0007628 36 18 0,000 0,06764162 0,0955746 ! patterning of blood vessels GO:0001569 43 18 0,000 0,06764162 0,09551935 ! heart looping GO:0001947 34 18 0,000 0,06764162 0,09546417 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,06764162 0,09540906 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,06764162 0,095354 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,06764162 0,09529901 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,06764162 0,09524408 ! epidermis morphogenesis GO:0048730 43 18 0,000 0,06764162 0,09518922 ! glycine metabolic process GO:0006544 30 18 0,000 0,06764162 0,09513442 ! glutamine metabolic process GO:0006541 29 18 0,000 0,06764162 0,09507968 ! response to retinoic acid GO:0032526 31 18 0,000 0,06764162 0,09502501 ! cell-substrate junction assembly GO:0007044 56 18 0,000 0,06764162 0,09497039 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,06764162 0,09491584 ! DNA integration GO:0015074 32 18 0,000 0,06764162 0,09486136 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,06764162 0,09480693 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,06764162 0,09475257 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,06764162 0,09469827 ! neural crest cell migration GO:0001755 41 18 0,000 0,06764162 0,09464403 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,06764162 0,09458986 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,06764162 0,09453575 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,06764162 0,09448169 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,06764162 0,0944277 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,06764162 0,09437378 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,06764162 0,09431991 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,06764162 0,09426611 ! detection of bacterium GO:0016045 22 18 0,000 0,06764162 0,09421236 ! defense response to virus GO:0051607 43 18 0,000 0,06764162 0,09415868 ! microspike assembly GO:0030035 46 18 0,000 0,06764162 0,09410506 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,06764162 0,0940515 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,07126335 0,09903092 ! positive regulation of translation GO:0045727 31 19 0,000 0,07126335 0,09897462 ! negative regulation of defense response GO:0031348 27 19 0,000 0,07126335 0,09891839 ! G1 phase of mitotic cell cycle GO:0000080 39 19 0,000 0,07126335 0,09886222 ! neuron maturation GO:0042551 46 19 0,000 0,07126335 0,09880611 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,07126335 0,09875006 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 0,07126335 0,09869408 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,07126335 0,09863817 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,07126335 0,09858231 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,07126335 0,09852652 ! inositol metabolic process GO:0006020 33 19 0,000 0,07126335 0,09847079 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,07126335 0,09841513 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,07126335 0,09835953 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,07126335 0,09830399 ! cerebral cortex development GO:0021987 40 19 0,000 0,07126335 0,09824851 ! pigmentation during development GO:0048066 42 19 0,000 0,07126335 0,0981931 ! response to vitamin A GO:0033189 32 19 0,000 0,07126335 0,09813775 ! heme metabolic process GO:0042168 40 19 0,000 0,07126335 0,09808246 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,07126335 0,09802723 ! response to fungus GO:0009620 26 19 0,000 0,07126335 0,09797207 ! peptide cross-linking GO:0018149 39 19 0,000 0,07126335 0,09791696 ! protein export from nucleus GO:0006611 40 19 0,000 0,07126335 0,09786192 ! heart process GO:0003015 32 19 0,000 0,07126335 0,09780694 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,07126335 0,09775203 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,07126335 0,09769717 ! cellular pigmentation GO:0033059 37 19 0,000 0,07126335 0,09764238 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,07126335 0,09758765 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,07126335 0,09753298 ! vitamin transport GO:0051180 31 19 0,000 0,07126335 0,09747837 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,07126335 0,09742382 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,07126335 0,09736933 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,07126335 0,0973149 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,07126335 0,09726054 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,07126335 0,09720623 ! cilium assembly GO:0042384 38 19 0,000 0,07126335 0,09715199 ! peptide hormone secretion GO:0030072 32 19 0,000 0,07126335 0,0970978 ! protein secretion GO:0009306 45 20 0,000 0,07487111 0,10195659 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,07487111 0,10189979 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,07487111 0,10184305 ! positive regulation of ossification GO:0045778 50 20 0,000 0,07487111 0,10178638 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,07487111 0,10172977 ! skin development GO:0043588 42 20 0,000 0,07487111 0,10167322 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,07487111 0,10161673 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,07487111 0,10156031 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,07487111 0,10150395 ! response to vitamin GO:0033273 36 20 0,000 0,07487111 0,10144765 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,07487111 0,10139142 ! forelimb morphogenesis GO:0035136 35 20 0,000 0,07487111 0,10133525 ! bile acid metabolic process GO:0008206 34 20 0,000 0,07487111 0,10127914 ! response to alkaloid GO:0043279 38 20 0,000 0,07487111 0,10122309 ! retinoid metabolic process GO:0001523 34 20 0,000 0,07487111 0,1011671 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 40 20 0,000 0,07487111 0,10111118 ! apoptotic mitochondrial changes GO:0008637 42 20 0,000 0,07487111 0,10105531 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,07487111 0,10099951 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,07487111 0,10094377 GO:0032392|DNA geometric change, ! cellular response to unfolded protein GO:0034620 35 20 0,000 0,07487111 0,1008881 GO:0030968|endoplasmic reticulum unfolded protein response, ! actin filament bundle formation GO:0051017 47 20 0,000 0,07487111 0,10083248 ! body fluid secretion GO:0007589 33 20 0,000 0,07487111 0,10077692 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,07487111 0,10072143 ! peptide secretion GO:0002790 38 20 0,000 0,07487111 0,100666 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,07487111 0,10061063 ! regulation of fatty acid metabolic process GO:0019217 45 20 0,000 0,07487111 0,10055532 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,07487111 0,10050006 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,07487111 0,10044488 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,07487111 0,10038975 ! cell-cell junction organization GO:0045216 43 20 0,000 0,07487111 0,10033468 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 0,000 0,07487111 0,10027967 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,07487111 0,10022472 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,07487111 0,10016983 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,07487111 0,10011501 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,07487111 0,10006024 ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,07487111 0,10000553 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,07487111 0,09995088 ! regulation of cell killing GO:0031341 46 21 0,000 0,07846495 0,10469136 ! hormone secretion GO:0046879 39 21 0,000 0,07846495 0,10463422 ! cAMP metabolic process GO:0046058 41 21 0,000 0,07846495 0,10457713 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,07846495 0,10452011 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,07846495 0,10446315 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,07846495 0,10440625 ! ovarian follicle development GO:0001541 39 21 0,000 0,07846495 0,10434942 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,07846495 0,10429265 ! cell structure disassembly during apoptosis GO:0006921 32 21 0,000 0,07846495 0,10423593 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,07846495 0,10417928 ! plasma membrane fusion GO:0045026 33 21 0,000 0,07846495 0,1041227 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,07846495 0,10406617 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,07846495 0,1040097 GO:0006692|prostanoid metabolic process, ! regulation of vasoconstriction GO:0019229 40 21 0,000 0,07846495 0,1039533 ! sensory perception of pain GO:0019233 33 21 0,000 0,07846495 0,10389696 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,07846495 0,10384067 ! diencephalon development GO:0021536 36 21 0,000 0,07846495 0,10378445 ! collagen fibril organization GO:0030199 62 21 0,000 0,07846495 0,10372829 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,07846495 0,10367219 ! negative regulation of intracellular transport GO:0032387 44 21 0,000 0,07846495 0,10361615 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,07846495 0,10356018 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 0,07846495 0,10350426 ! collagen catabolic process GO:0030574 29 21 0,000 0,07846495 0,1034484 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,07846495 0,1033926 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,07846495 0,10333686 ! actin filament-based movement GO:0030048 47 21 0,000 0,07846495 0,10328119 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 0,000 0,07846495 0,10322557 ! positive regulation of protein catabolic process GO:0045732 44 22 0,000 0,08204494 0,10787717 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,08204494 0,10781914 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,08204494 0,10776118 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,08204494 0,10770327 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,08204494 0,10764543 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,08204494 0,10758765 ! hindlimb morphogenesis GO:0035137 47 22 0,000 0,08204494 0,10752993 ! cellular response to starvation GO:0009267 37 22 0,000 0,08204494 0,10747227 ! vacuolar transport GO:0007034 41 22 0,000 0,08204494 0,10741468 ! central nervous system neuron development GO:0021954 47 22 0,000 0,08204494 0,10735714 ! fucose metabolic process GO:0006004 44 22 0,000 0,08204494 0,10729967 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,08204494 0,10724226 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,08204494 0,10718491 ! apoptotic nuclear changes GO:0030262 34 22 0,000 0,08204494 0,10712763 ! ureteric bud development GO:0001657 50 22 0,000 0,08204494 0,1070704 ! stem cell differentiation GO:0048863 57 22 0,000 0,08204494 0,10701324 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,08204494 0,10695613 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 0,08204494 0,10689909 ! cytolysis GO:0019835 27 22 0,000 0,08204494 0,10684211 ! renal system process GO:0003014 42 22 0,000 0,08204494 0,10678518 ! vasodilation GO:0042311 40 22 0,000 0,08204494 0,10672832 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,08204494 0,10667152 ! G1 phase GO:0051318 44 22 0,000 0,08204494 0,10661478 ! detection of chemical stimulus GO:0009593 42 22 0,000 0,08204494 0,1065581 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,08204494 0,10650148 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,08204494 0,10644492 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,08204494 0,10638842 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,08204494 0,10633198 ! sarcomere organization GO:0045214 32 22 0,000 0,08204494 0,1062756 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,08204494 0,10621928 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,08204494 0,10616302 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,08204494 0,10610682 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,08204494 0,10605068 ! gut development GO:0048565 44 22 0,000 0,08204494 0,1059946 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,08204494 0,10593858 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 0,000 0,08204494 0,10588261 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,08204494 0,10582671 ! protein stabilization GO:0050821 41 22 0,000 0,08204494 0,10577087 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,08561112 0,11031011 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,08561112 0,11025196 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,08561112 0,11019387 ! viral genome replication GO:0019079 44 23 0,000 0,08561112 0,11013584 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,08561112 0,11007788 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,08561112 0,11001997 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,08561112 0,10996213 ! regeneration GO:0031099 42 23 0,000 0,08561112 0,10990434 ! axis specification GO:0009798 43 23 0,000 0,08561112 0,10984662 ! regulation of cell-matrix adhesion GO:0001952 81 23 0,000 0,08561112 0,10978896 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 51 23 0,000 0,08561112 0,10973136 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,08561112 0,10967381 ! activation of pro-apoptotic gene products GO:0008633 51 23 0,000 0,08561112 0,10961633 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,08561112 0,10955891 ! peroxisome organization GO:0007031 43 23 0,000 0,08561112 0,10950155 ! lysosome organization GO:0007040 47 23 0,000 0,08561112 0,10944425 ! vesicle targeting GO:0006903 49 23 0,000 0,08561112 0,10938701 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 0,000 0,08561112 0,10932983 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,08561112 0,10927271 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,08561112 0,10921565 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,08561112 0,10915865 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,08561112 0,1091017 ! DNA modification GO:0006304 36 23 0,000 0,08561112 0,10904482 ! fatty acid transport GO:0015908 47 23 0,000 0,08561112 0,108988 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,08561112 0,10893123 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,08561112 0,10887453 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,08561112 0,10881788 ! hormone transport GO:0009914 41 23 0,000 0,08561112 0,10876129 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,08561112 0,10870476 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,08561112 0,10864829 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,08561112 0,10859188 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,08916354 0,1130392 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,08916354 0,11298057 GO:0016444|somatic cell DNA recombination, ! DNA catabolic process, endonucleolytic GO:0000737 38 24 0,000 0,08916354 0,112922 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,08916354 0,11286349 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,08916354 0,11280504 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,08916354 0,11274665 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,08916354 0,11268833 ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,08916354 0,11263006 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,08916354 0,11257185 GO:0042278|purine nucleoside metabolic process, ! positive regulation of cytoskeleton organization GO:0051495 52 24 0,000 0,08916354 0,11251371 ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,08916354 0,11245562 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,08916354 0,11239759 GO:0051693|actin filament capping, ! regulation of viral reproduction GO:0050792 41 24 0,000 0,08916354 0,11233963 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,08916354 0,11228172 GO:0002708|positive regulation of lymphocyte mediated immunity, ! leukotriene metabolic process GO:0006691 47 24 0,000 0,08916354 0,11222387 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,08916354 0,11216608 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,08916354 0,11210836 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,08916354 0,11205069 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,08916354 0,11199308 ! platelet activation GO:0030168 41 24 0,000 0,08916354 0,11193553 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,08916354 0,11187804 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,08916354 0,1118206 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,08916354 0,11176323 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,08916354 0,11170592 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,08916354 0,11164866 ! regulation of amine transport GO:0051952 41 24 0,000 0,08916354 0,11159146 ! protein import into nucleus, translocation GO:0000060 51 25 0,000 0,09270227 0,1159609 ! myeloid leukocyte differentiation GO:0002573 46 25 0,000 0,09270227 0,11590155 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,09270227 0,11584227 ! leukocyte adhesion GO:0007159 55 25 0,000 0,09270227 0,11578305 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,09270227 0,11572388 ! phototransduction GO:0007602 37 25 0,000 0,09270227 0,11566478 ! keratinization GO:0031424 37 25 0,000 0,09270227 0,11560574 ! vacuole organization GO:0007033 49 25 0,000 0,09270227 0,11554675 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,09270227 0,11548783 ! receptor metabolic process GO:0043112 53 25 0,000 0,09270227 0,11542897 ! chromosome condensation GO:0030261 48 25 0,000 0,09270227 0,11537017 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,09270227 0,11531142 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,09270227 0,11525274 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,09270227 0,11519412 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,09270227 0,11513555 ! immunoglobulin production GO:0002377 62 25 0,000 0,09270227 0,11507705 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,09270227 0,11501861 ! leukocyte homeostasis GO:0001776 50 25 0,000 0,09270227 0,11496022 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,09270227 0,1149019 ! liver development GO:0001889 55 25 0,000 0,09270227 0,11484363 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,09622734 0,11915022 ! initiation of viral infection GO:0019059 60 26 0,000 0,09622734 0,11908986 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,09622734 0,11902956 ! molting cycle process GO:0022404 52 26 0,000 0,09622734 0,11896933 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,09622734 0,11890915 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,09622734 0,11884903 GO:0006479|protein amino acid methylation, ! spinal cord development GO:0021510 54 26 0,000 0,09622734 0,11878898 ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,09622734 0,11872899 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,09622734 0,11866905 ! digestive system process GO:0022600 49 26 0,000 0,09622734 0,11860918 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,09622734 0,11854937 ! regulation of cellular ketone metabolic process GO:0010565 51 26 0,000 0,09622734 0,11848961 ! osteoblast differentiation GO:0001649 63 26 0,000 0,09622734 0,11842992 ! neural crest cell development GO:0014032 59 26 0,000 0,09622734 0,11837029 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,09622734 0,11831072 ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,09622734 0,1182512 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,09622734 0,11819175 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,09622734 0,11813236 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,09622734 0,11807302 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,09622734 0,11801375 ! regulation of blood coagulation GO:0030193 46 26 0,000 0,09622734 0,11795454 ! positive regulation of nuclear division GO:0051785 41 26 0,000 0,09622734 0,11789538 GO:0045840|positive regulation of mitosis, ! regulation of osteoblast differentiation GO:0045667 68 26 0,000 0,09622734 0,11783629 ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,09622734 0,11777725 ! telomere organization GO:0032200 46 26 0,000 0,09622734 0,11771827 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,09622734 0,11765935 ! neural tube closure GO:0001843 58 26 0,000 0,09622734 0,1176005 GO:0060606|tube closure, ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,09622734 0,1175417 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,09622734 0,11748295 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,09973882 0,12170925 ! embryonic pattern specification GO:0009880 49 27 0,000 0,09973882 0,12164849 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,09973882 0,12158779 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,09973882 0,12152715 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,09973882 0,12146656 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,09973882 0,12140604 ! iron ion transport GO:0006826 65 27 0,000 0,09973882 0,12134558 ! superoxide metabolic process GO:0006801 41 27 0,000 0,09973882 0,12128518 ! tube lumen formation GO:0035148 59 27 0,000 0,09973882 0,12122484 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,09973882 0,12116456 ! mitochondrial membrane organization GO:0007006 60 27 0,000 0,09973882 0,12110434 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,09973882 0,12104418 ! response to starvation GO:0042594 47 27 0,000 0,09973882 0,12098408 ! response to toxin GO:0009636 49 27 0,000 0,09973882 0,12092403 ! regulation of chromosome organization GO:0033044 49 27 0,000 0,09973882 0,12086405 ! cellular response to nutrient levels GO:0031669 45 27 0,000 0,09973882 0,12080413 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,09973882 0,12074427 ! leukocyte proliferation GO:0070661 59 27 0,000 0,09973882 0,12068446 GO:0032943|mononuclear cell proliferation, ! neuron fate commitment GO:0048663 52 28 0,000 0,10323675 0,12485514 ! circadian rhythm GO:0007623 56 28 0,000 0,10323675 0,12479336 ! fat cell differentiation GO:0045444 57 28 0,000 0,10323675 0,12473164 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,10323675 0,12466998 ! sperm motility GO:0030317 37 28 0,000 0,10323675 0,12460839 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,10323675 0,12454685 ! base-excision repair GO:0006284 41 28 0,000 0,10323675 0,12448538 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,10323675 0,12442396 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,10323675 0,12436261 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,10323675 0,12430132 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,10323675 0,12424009 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,10323675 0,12417891 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,10323675 0,1241178 ! glutathione metabolic process GO:0006749 42 28 0,000 0,10323675 0,12405675 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,10323675 0,12399576 ! lipid oxidation GO:0034440 48 28 0,000 0,10323675 0,12393483 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,10323675 0,12387396 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,10323675 0,12381314 ! translational initiation GO:0006413 66 29 0,000 0,10672119 0,12792927 ! cellular iron ion homeostasis GO:0006879 57 29 0,000 0,10672119 0,12786653 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,10672119 0,12780385 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! autophagy GO:0006914 47 29 0,000 0,10672119 0,12774123 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,10672119 0,12767868 ! primary neural tube formation GO:0014020 61 29 0,000 0,10672119 0,12761618 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,10672119 0,12755375 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,10672119 0,12749137 ! synaptogenesis GO:0007416 46 29 0,000 0,10672119 0,12742906 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,10672119 0,12736681 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,10672119 0,12730462 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,10672119 0,12724249 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,11019218 0,13131683 ! negative regulation of protein complex assembly GO:0031333 68 30 0,000 0,11019218 0,13125281 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,11019218 0,13118884 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,11019218 0,13112494 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,11019218 0,1310611 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,11019218 0,13099733 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,11019218 0,13093361 ! acute-phase response GO:0006953 50 30 0,000 0,11019218 0,13086996 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,11019218 0,13080637 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,11019218 0,13074284 ! negative regulation of protein kinase cascade GO:0010741 72 30 0,000 0,11019218 0,13067937 ! determination of left/right symmetry GO:0007368 53 30 0,000 0,11019218 0,13061597 ! cell fate determination GO:0001709 64 30 0,000 0,11019218 0,13055262 ! positive regulation of multicellular organism growth GO:0040018 55 30 0,000 0,11019218 0,13048934 ! phospholipid transport GO:0015914 65 30 0,000 0,11019218 0,13042612 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,11019218 0,13036296 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,11019218 0,13029986 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,11019218 0,13023682 ! negative regulation of transcription regulator activity GO:0090048 57 30 0,000 0,11019218 0,13017384 GO:0043433|negative regulation of transcription factor activity, ! tissue homeostasis GO:0001894 50 30 0,000 0,11019218 0,13011093 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 52 30 0,000 0,11019218 0,13004807 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,11364979 0,13406395 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,11364979 0,13399925 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,11364979 0,13393461 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,11364979 0,13387003 ! cell junction assembly GO:0034329 85 31 0,000 0,11364979 0,13380551 ! regulation of innate immune response GO:0045088 57 31 0,000 0,11364979 0,13374106 ! ovulation cycle process GO:0022602 55 31 0,000 0,11364979 0,13367667 ! peptide transport GO:0015833 60 31 0,000 0,11364979 0,13361234 ! male gonad development GO:0008584 56 31 0,000 0,11364979 0,13354807 ! iron ion homeostasis GO:0055072 60 31 0,000 0,11364979 0,13348387 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,11364979 0,13341972 ! detection of light stimulus GO:0009583 44 31 0,000 0,11364979 0,13335564 ! natural killer cell activation GO:0030101 50 31 0,000 0,11364979 0,13329162 ! cofactor catabolic process GO:0051187 54 31 0,000 0,11364979 0,13322766 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,11364979 0,13316376 ! eye morphogenesis GO:0048592 65 31 0,000 0,11364979 0,13309992 ! response to heat GO:0009408 54 31 0,000 0,11364979 0,13303615 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,11364979 0,13297243 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,11709406 0,13693671 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,11709406 0,13687119 ! collagen metabolic process GO:0032963 49 32 0,000 0,11709406 0,13680573 ! spindle organization GO:0007051 50 32 0,000 0,11709406 0,13674034 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,11709406 0,13667501 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,11709406 0,13660974 ! metanephros development GO:0001656 81 32 0,000 0,11709406 0,13654453 ! response to mechanical stimulus GO:0009612 60 32 0,000 0,11709406 0,13647939 ! mesoderm formation GO:0001707 73 32 0,000 0,11709406 0,1364143 ! ovulation cycle GO:0042698 57 32 0,000 0,11709406 0,13634928 ! BMP signaling pathway GO:0030509 71 32 0,000 0,11709406 0,13628432 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,11709406 0,13621942 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,11709406 0,13615459 ! gene silencing GO:0016458 71 32 0,000 0,11709406 0,13608982 ! regulation of pH GO:0006885 56 33 0,000 0,12052504 0,14001078 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,12052504 0,13994424 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,12052504 0,13987776 GO:0055092|sterol homeostasis, ! pigment biosynthetic process GO:0046148 73 33 0,000 0,12052504 0,13981134 ! positive regulation of gene-specific transcription GO:0043193 70 33 0,000 0,12052504 0,13974498 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,12052504 0,13967869 ! triglyceride metabolic process GO:0006641 46 33 0,000 0,12052504 0,13961246 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,12052504 0,13954629 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,12052504 0,13948019 ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,12052504 0,13941415 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,12052504 0,13934817 ! negative regulation of protein transport GO:0051224 74 33 0,000 0,12052504 0,13928225 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,12052504 0,1392164 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,12394279 0,14309652 ! glial cell differentiation GO:0010001 67 34 0,000 0,12394279 0,14302892 ! post-embryonic development GO:0009791 76 34 0,000 0,12394279 0,14296139 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,12394279 0,14289393 ! cholesterol transport GO:0030301 62 34 0,000 0,12394279 0,14282652 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,12394279 0,14275918 ! spliceosome assembly GO:0000245 75 34 0,000 0,12394279 0,14269191 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,12394279 0,1426247 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,12394279 0,14255755 ! formation of primary germ layer GO:0001704 76 34 0,000 0,12394279 0,14249046 ! cell fate specification GO:0001708 56 34 0,000 0,12394279 0,14242344 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,12394279 0,14235648 ! adult locomotory behavior GO:0008344 62 34 0,000 0,12394279 0,14228958 ! DNA damage checkpoint GO:0000077 78 35 0,000 0,12734735 0,14612944 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,12734735 0,14606083 ! negative regulation of secretion GO:0051048 68 35 0,000 0,12734735 0,14599229 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,12734735 0,14592381 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,12734735 0,1458554 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,12734735 0,14578705 ! regulation of striated muscle tissue development GO:0016202 81 35 0,000 0,12734735 0,14571877 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,12734735 0,14565055 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,12734735 0,14558239 ! ceramide metabolic process GO:0006672 72 35 0,000 0,12734735 0,1455143 ! sterol transport GO:0015918 63 35 0,000 0,12734735 0,14544627 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,12734735 0,1453783 ! placenta development GO:0001890 53 35 0,000 0,12734735 0,1453104 ! vesicle localization GO:0051648 70 35 0,000 0,12734735 0,14524256 ! regulation of muscle development GO:0048634 82 36 0,000 0,13073877 0,14904098 ! mitotic sister chromatid segregation GO:0000070 63 36 0,000 0,13073877 0,14897146 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,13073877 0,14890201 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,13073877 0,14883263 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,13073877 0,14876331 ! negative regulation of DNA binding GO:0043392 67 36 0,000 0,13073877 0,14869405 ! positive regulation of cell development GO:0010720 85 36 0,000 0,13073877 0,14862486 ! protein targeting to membrane GO:0006612 75 36 0,000 0,13073877 0,14855573 ! regulation of proteolysis GO:0030162 77 36 0,000 0,13073877 0,14848667 ! negative regulation of hydrolase activity GO:0051346 66 36 0,000 0,13073877 0,14841767 ! aerobic respiration GO:0009060 56 36 0,000 0,13073877 0,14834873 ! cytokine production GO:0001816 68 36 0,000 0,13073877 0,14827986 ! embryonic organ development GO:0048568 67 36 0,000 0,13073877 0,14821105 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,13073877 0,14814231 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 0,000 0,13411711 0,15189991 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! negative regulation of cell adhesion GO:0007162 94 37 0,000 0,13411711 0,15182952 ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,13411711 0,15175919 ! sister chromatid segregation GO:0000819 65 37 0,000 0,13411711 0,15168893 ! odontogenesis GO:0042476 74 37 0,000 0,13411711 0,15161874 ! cell junction organization GO:0034330 96 37 0,000 0,13411711 0,15154861 ! maintenance of protein location in cell GO:0032507 89 37 0,000 0,13411711 0,15147855 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,13411711 0,15140855 ! androgen receptor signaling pathway GO:0030521 81 37 0,000 0,13411711 0,15133861 ! meiosis I GO:0007127 74 38 0,000 0,13748241 0,15506442 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,13748241 0,15499286 ! organic anion transport GO:0015711 82 38 0,000 0,13748241 0,15492137 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,13748241 0,15484995 ! neutral lipid metabolic process GO:0006638 54 38 0,000 0,13748241 0,15477859 GO:0006639|acylglycerol metabolic process, ! DNA integrity checkpoint GO:0031570 82 38 0,000 0,13748241 0,15470729 ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,13748241 0,15463607 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,13748241 0,1545649 ! regulation of protein stability GO:0031647 77 38 0,000 0,13748241 0,15449381 ! spermatid development GO:0007286 69 38 0,000 0,13748241 0,15442277 ! pigment metabolic process GO:0042440 87 38 0,000 0,13748241 0,15435181 ! neural tube formation GO:0001841 79 38 0,000 0,13748241 0,15428091 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,14083473 0,15797027 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,14083473 0,15789777 ! negative regulation of binding GO:0051100 71 39 0,000 0,14083473 0,15782534 ! mitotic cell cycle checkpoint GO:0007093 76 39 0,000 0,14083473 0,15775298 ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,14083473 0,15768068 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,14083473 0,15760845 ! erythrocyte homeostasis GO:0034101 75 39 0,000 0,14083473 0,15753629 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,14083473 0,15746419 ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,14083473 0,15739215 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,14417412 0,16105046 GO:0006956|complement activation, ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,14417412 0,16097686 ! nucleus organization GO:0006997 73 40 0,000 0,14417412 0,16090332 ! lipid homeostasis GO:0055088 75 40 0,000 0,14417412 0,16082985 ! mismatch repair GO:0006298 58 40 0,000 0,14417412 0,16075644 ! glycerol ether metabolic process GO:0006662 57 40 0,000 0,14417412 0,1606831 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,14417412 0,16060983 ! RNA export from nucleus GO:0006405 61 41 0,000 0,14750061 0,16424066 ! mRNA catabolic process GO:0006402 79 41 0,000 0,14750061 0,16416583 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,14750061 0,16409107 ! regulation of hormone secretion GO:0046883 69 41 0,000 0,14750061 0,16401638 ! establishment or maintenance of cell polarity GO:0007163 96 41 0,000 0,14750061 0,16394176 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,14750061 0,16386721 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,14750061 0,16379273 ! gliogenesis GO:0042063 91 41 0,000 0,14750061 0,16371831 ! feeding behavior GO:0007631 69 41 0,000 0,14750061 0,16364396 ! multicellular organismal metabolic process GO:0044236 64 41 0,000 0,14750061 0,16356968 ! mesenchymal cell development GO:0014031 94 41 0,000 0,14750061 0,16349546 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! monovalent inorganic cation homeostasis GO:0055067 72 41 0,000 0,14750061 0,16342131 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,14750061 0,16334723 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 95 41 0,000 0,14750061 0,16327322 ! spermatid differentiation GO:0048515 73 41 0,000 0,14750061 0,16319927 ! embryonic epithelial tube formation GO:0001838 85 41 0,000 0,14750061 0,16312539 ! RNA modification GO:0009451 64 41 0,000 0,14750061 0,16305158 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,15081427 0,1666392 ! ear morphogenesis GO:0042471 64 42 0,000 0,15081427 0,16656387 ! organic ether metabolic process GO:0018904 59 42 0,000 0,15081427 0,1664886 ! T cell differentiation GO:0030217 93 42 0,000 0,15081427 0,1664134 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,15081427 0,16633827 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,15081427 0,16626321 ! regulation of protein secretion GO:0050708 77 42 0,000 0,15081427 0,16618821 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,15081427 0,16611329 ! epithelial cell differentiation GO:0030855 83 43 0,000 0,15411515 0,16967251 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,15411515 0,16959608 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,15411515 0,16951972 ! regulation of tube size GO:0035150 76 43 0,000 0,15411515 0,16944343 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,15411515 0,16936721 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,15411515 0,16929106 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,15411515 0,16921497 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,15411515 0,16913895 ! ion transmembrane transport GO:0034220 79 43 0,000 0,15411515 0,169063 ! neuron migration GO:0001764 85 43 0,000 0,15411515 0,16898712 ! regulation of myeloid cell differentiation GO:0045637 105 43 0,000 0,15411515 0,16891131 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,15740328 0,17243777 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 0,000 0,15740328 0,17236048 ! phagocytosis GO:0006909 105 44 0,000 0,15740328 0,17228325 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,15740328 0,1722061 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,16067873 0,17571089 ! branching morphogenesis of a tube GO:0048754 102 45 0,000 0,16067873 0,17563228 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,16067873 0,17555373 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! keratinocyte differentiation GO:0030216 81 45 0,000 0,16067873 0,17547525 ! biopolymer methylation GO:0043414 91 45 0,000 0,16067873 0,17539684 ! B cell differentiation GO:0030183 124 45 0,000 0,16067873 0,17531851 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,16067873 0,17524024 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,16067873 0,17516204 ! maintenance of location in cell GO:0051651 101 45 0,000 0,16067873 0,17508392 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,16394154 0,1785596 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,16394154 0,17848002 ! glycolysis GO:0006096 71 46 0,000 0,16394154 0,17840052 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,16394154 0,17832109 ! pigmentation GO:0043473 103 46 0,000 0,16394154 0,17824173 ! cell growth GO:0016049 90 46 0,000 0,16394154 0,17816244 ! neural tube development GO:0021915 91 47 0,000 0,16719175 0,1816138 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,16719175 0,18153309 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,17042942 0,18496627 ! mitochondrial transport GO:0006839 94 48 0,000 0,17042942 0,18488413 ! regulation of JAK-STAT cascade GO:0046425 76 48 0,000 0,17042942 0,18480207 ! cellular component disassembly GO:0022411 89 48 0,000 0,17042942 0,18472008 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 0,000 0,17042942 0,18463817 ! male sex differentiation GO:0046661 93 48 0,000 0,17042942 0,18455632 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,17042942 0,18447455 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,17042942 0,18439286 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,17042942 0,18431123 ! methylation GO:0032259 97 48 0,000 0,17042942 0,18422968 ! response to calcium ion GO:0051592 94 49 0,000 0,17365459 0,18763298 ! detection of stimulus involved in sensory perception GO:0050906 75 49 0,000 0,17365459 0,18755003 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,17365459 0,18746715 ! JNK cascade GO:0007254 106 49 0,000 0,17365459 0,18738435 ! regulation of ion transport GO:0043269 86 50 0,000 0,17686732 0,19076682 ! endocrine system development GO:0035270 109 50 0,000 0,17686732 0,19068264 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,17686732 0,19059852 ! activation of caspase activity GO:0006919 95 50 0,000 0,17686732 0,19051449 ! regulation of ossification GO:0030278 123 50 0,000 0,17686732 0,19043052 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,17686732 0,19034663 GO:0019724|B cell mediated immunity, ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,17686732 0,19026281 ! epidermal cell differentiation GO:0009913 87 50 0,000 0,17686732 0,19017907 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,17686732 0,1900954 ! viral infectious cycle GO:0019058 104 51 0,000 0,18006764 0,19344998 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,18006764 0,19336494 ! peptide metabolic process GO:0006518 80 51 0,000 0,18006764 0,19327998 ! response to temperature stimulus GO:0009266 84 51 0,000 0,18006764 0,1931951 ! detection of abiotic stimulus GO:0009582 80 51 0,000 0,18006764 0,19311029 ! Notch signaling pathway GO:0007219 111 52 0,000 0,18325561 0,19644294 ! morphogenesis of embryonic epithelium GO:0016331 106 52 0,000 0,18325561 0,19635678 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,18325561 0,1962707 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,18325561 0,19618469 ! excretion GO:0007588 87 52 0,000 0,18325561 0,19609876 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,18325561 0,1960129 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,18325561 0,19592712 ! morphogenesis of a branching structure GO:0001763 116 52 0,000 0,18325561 0,19584141 ! amino acid activation GO:0043038 98 52 0,000 0,18325561 0,19575578 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,18643128 0,19906102 ! inner ear development GO:0048839 89 53 0,000 0,18643128 0,19897405 ! chromatin remodeling GO:0006338 122 53 0,000 0,18643128 0,19888717 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,18643128 0,19880035 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,18643128 0,19871362 ! vesicle organization GO:0016050 127 53 0,000 0,18643128 0,19862696 ! regulation of neuron apoptosis GO:0043523 117 53 0,000 0,18643128 0,19854037 ! regulation of translational initiation GO:0006446 87 54 0,000 0,18959468 0,20182127 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,18959468 0,20173337 ! membrane fusion GO:0006944 122 54 0,000 0,18959468 0,20164554 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,18959468 0,2015578 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,18959468 0,20147012 ! epithelial tube morphogenesis GO:0060562 114 54 0,000 0,18959468 0,20138253 ! RNA catabolic process GO:0006401 103 55 0,000 0,19274588 0,20464067 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,19274588 0,20455177 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,19274588 0,20446295 ! regulation of multicellular organism growth GO:0040014 90 55 0,000 0,19274588 0,20437421 ! regulation of protein polymerization GO:0032271 117 55 0,000 0,19274588 0,20428555 ! glucose catabolic process GO:0006007 88 56 0,000 0,19588491 0,20752248 ! RNA elongation GO:0006354 90 56 0,000 0,19588491 0,20743253 ! chloride transport GO:0006821 102 57 0,000 0,19901182 0,21065246 ! positive regulation of caspase activity GO:0043280 108 57 0,000 0,19901182 0,21056123 GO:0010952|positive regulation of peptidase activity, ! regulation of actin filament length GO:0030832 118 58 0,000 0,20212666 0,21376426 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,20212666 0,21367176 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,20212666 0,21357934 ! gastrulation GO:0007369 122 58 0,000 0,20212666 0,213487 ! positive regulation of organelle organization GO:0010638 108 58 0,000 0,20212666 0,21339475 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,20212666 0,21330257 ! maintenance of location GO:0051235 124 58 0,000 0,20212666 0,21321047 ! nuclear export GO:0051168 110 59 0,000 0,20522948 0,21639 ! establishment of organelle localization GO:0051656 122 59 0,000 0,20522948 0,21629664 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,20832032 0,21945948 ! DNA catabolic process GO:0006308 94 60 0,000 0,20832032 0,21936489 ! regulation of endocytosis GO:0030100 104 60 0,000 0,20832032 0,21927037 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,20832032 0,21917594 ! adult behavior GO:0030534 104 60 0,000 0,20832032 0,21908159 ! kidney development GO:0001822 133 60 0,000 0,20832032 0,21898732 ! positive regulation of secretion GO:0051047 110 61 0,000 0,21139922 0,2221283 ! regulation of cellular component size GO:0032535 125 61 0,000 0,21139922 0,2220328 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,21139922 0,22193739 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,21139922 0,22184205 ! camera-type eye development GO:0043010 126 61 0,000 0,21139922 0,2217468 ! proton transport GO:0015992 117 61 0,000 0,21139922 0,22165163 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,21446624 0,22477092 ! tRNA processing GO:0008033 102 62 0,000 0,21446624 0,22467453 ! regulation of protein complex assembly GO:0043254 132 63 0,000 0,21752141 0,22777745 ! regulation of mitosis GO:0007088 112 63 0,000 0,21752141 0,22767986 GO:0051783|regulation of nuclear division, ! mesoderm development GO:0007498 128 63 0,000 0,21752141 0,22758236 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,21752141 0,22748493 ! hydrogen transport GO:0006818 121 64 0,000 0,22056479 0,23056901 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,22056479 0,23047039 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,22359641 0,23353828 ! lymphocyte mediated immunity GO:0002449 122 65 0,000 0,22359641 0,23343847 ! multicellular organism reproduction GO:0032504 123 65 0,000 0,22359641 0,23333876 GO:0048609|reproductive process in a multicellular organism, ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,22359641 0,23323913 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,22359641 0,23313958 ! ear development GO:0043583 114 66 0,000 0,22661633 0,23618758 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,22661633 0,23608686 ! steroid hormone receptor signaling pathway GO:0030518 146 66 0,000 0,22661633 0,23598623 ! embryonic limb morphogenesis GO:0030326 139 67 0,000 0,22962459 0,23901699 GO:0035113|embryonic appendage morphogenesis, ! chromosome segregation GO:0007059 127 67 0,000 0,22962459 0,23891519 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,22962459 0,23881348 ! secondary metabolic process GO:0019748 125 67 0,000 0,22962459 0,23871186 ! regulation of cellular response to stress GO:0080135 142 68 0,000 0,23262123 0,24172423 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,23262123 0,24162145 ! hexose catabolic process GO:0019320 113 68 0,000 0,23262123 0,24151877 ! detection of external stimulus GO:0009581 102 68 0,000 0,23262123 0,24141617 ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,23262123 0,24131365 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,23560629 0,24430653 ! urogenital system development GO:0001655 149 69 0,000 0,23560629 0,24420288 ! homeostasis of number of cells GO:0048872 131 69 0,000 0,23560629 0,24409931 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,23560629 0,24399584 ! cell redox homeostasis GO:0045454 114 70 0,000 0,23857983 0,24697057 ! protein maturation by peptide bond cleavage GO:0051605 118 70 0,000 0,23857983 0,24686596 ! cell cycle checkpoint GO:0000075 145 71 0,000 0,24154189 0,24982508 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,24154189 0,24971936 ! cAMP-mediated signaling GO:0019933 124 71 0,000 0,24154189 0,24961372 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 0,000 0,24154189 0,24950818 ! appendage morphogenesis GO:0035107 150 72 0,000 0,24449251 0,25244936 GO:0035108|limb morphogenesis, ! B cell activation GO:0042113 179 72 0,000 0,24449251 0,25234271 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,24449251 0,25223615 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,24449251 0,25212967 ! regulation of MAPKKK cascade GO:0043408 157 72 0,000 0,24449251 0,25202329 ! appendage development GO:0048736 151 73 0,000 0,24743173 0,25494547 GO:0060173|limb development, ! humoral immune response GO:0006959 115 73 0,000 0,24743173 0,25483799 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,24743173 0,2547306 ! regulation of immune effector process GO:0002697 156 73 0,000 0,24743173 0,2546233 ! acute inflammatory response GO:0002526 118 74 0,000 0,2503596 0,25752779 ! organelle localization GO:0051640 155 74 0,000 0,2503596 0,2574194 ! transition metal ion transport GO:0000041 143 75 0,000 0,25327616 0,26030865 ! leukocyte mediated immunity GO:0002443 136 75 0,000 0,25327616 0,26019918 ! eye development GO:0001654 155 75 0,000 0,25327616 0,26008981 ! rhythmic process GO:0048511 142 75 0,000 0,25327616 0,25998053 ! regulation of actin cytoskeleton organization GO:0032956 167 76 0,000 0,25618145 0,26285228 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,25618145 0,26274193 ! regulation of blood pressure GO:0008217 134 76 0,000 0,25618145 0,26263168 ! lymphocyte differentiation GO:0030098 193 76 0,000 0,25618145 0,26252151 ! amine catabolic process GO:0009310 136 77 0,000 0,25907552 0,26537589 ! neurotransmitter transport GO:0006836 142 77 0,000 0,25907552 0,26526467 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,25907552 0,26515354 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,25907552 0,26504251 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,25907552 0,26493156 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,26195842 0,26776754 ! antigen processing and presentation GO:0019882 117 78 0,000 0,26195842 0,26765555 ! blood coagulation GO:0007596 151 79 0,000 0,26483017 0,27047664 GO:0050817|coagulation, ! regulation of actin filament-based process GO:0032970 170 79 0,000 0,26483017 0,27036361 ! steroid biosynthetic process GO:0006694 146 79 0,000 0,26483017 0,27025067 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 0,000 0,26769084 0,27305583 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 0,000 0,27054045 0,27584738 ! protein import into nucleus GO:0006606 174 82 0,000 0,27337905 0,27862538 ! regulation of adenylate cyclase activity GO:0045761 165 83 0,000 0,27620669 0,28138989 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,27620669 0,28127259 ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,27620669 0,2811554 ! nuclear import GO:0051170 177 83 0,000 0,27620669 0,2810383 ! inorganic anion transport GO:0015698 156 83 0,000 0,27620669 0,28092129 ! response to metal ion GO:0010038 158 84 0,000 0,27902341 0,28366799 ! T cell activation GO:0042110 189 84 0,000 0,27902341 0,28354999 ! digestion GO:0007586 130 84 0,000 0,27902341 0,28343209 ! hemostasis GO:0007599 165 85 0,000 0,28182924 0,28616327 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,28182924 0,28604438 ! regulation of cyclase activity GO:0031279 168 85 0,000 0,28182924 0,28592559 ! regulation of cAMP biosynthetic process GO:0030817 173 86 0,000 0,28462423 0,28864134 ! regulation of lyase activity GO:0051339 169 86 0,000 0,28462423 0,28852157 ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,28740842 0,29122305 ! mitochondrion organization GO:0007005 159 87 0,000 0,28740842 0,29110231 ! nucleosome assembly GO:0006334 126 87 0,000 0,28740842 0,29098167 ! cellular respiration GO:0045333 143 88 0,000 0,29018185 0,29366788 ! amine biosynthetic process GO:0009309 146 88 0,000 0,29018185 0,29354628 ! sensory perception of smell GO:0007608 117 88 0,000 0,29018185 0,29342478 ! chromatin assembly GO:0031497 128 88 0,000 0,29018185 0,29330338 ! one-carbon metabolic process GO:0006730 167 88 0,000 0,29018185 0,29318208 ! regulation of cAMP metabolic process GO:0030814 182 89 0,000 0,29294457 0,29585101 ! tube morphogenesis GO:0035239 194 89 0,000 0,29294457 0,29572875 ! cellular defense response GO:0006968 123 89 0,000 0,29294457 0,2956066 ! protein localization in nucleus GO:0034504 192 89 0,000 0,29294457 0,29548455 ! response to inorganic substance GO:0010035 173 90 0,000 0,29569661 0,29813736 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,29569661 0,29801437 ! response to unfolded protein GO:0006986 139 90 0,000 0,29569661 0,29789147 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 0,000 0,29843802 0,3005293 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! defense response to bacterium GO:0042742 112 91 0,000 0,29843802 0,30040547 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,30116883 0,30302943 ! vitamin metabolic process GO:0006766 153 93 0,000 0,30388909 0,30564062 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,30659884 0,30823908 ! female pregnancy GO:0007565 166 94 0,000 0,30659884 0,30811229 ! sterol metabolic process GO:0016125 166 94 0,000 0,30659884 0,3079856 ! nucleosome organization GO:0034728 143 95 0,000 0,30929812 0,31056938 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,30929812 0,31044179 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 0,000 0,30929812 0,31031429 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,30929812 0,31018691 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,30929812 0,31005963 ! response to protein stimulus GO:0051789 158 96 0,000 0,31198696 0,31262681 ! transcription initiation GO:0006352 171 97 0,000 0,31466542 0,31518147 ! leukocyte differentiation GO:0002521 232 98 0,000 0,31733352 0,31772368 ! regulation of nucleotide metabolic process GO:0006140 197 98 0,000 0,31733352 0,31759352 ! mRNA transport GO:0051028 185 100 0,000 0,32263882 0,32277094 ! hormone metabolic process GO:0042445 171 100 0,000 0,32263882 0,32263882