pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6789-VanDeVijver-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/vantveer-oligo_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! angiogenesis GO:0001525 65 64 6,000 6,985E-07 1,287E-03 ! blood vessel development GO:0001568 95 94 7,000 7,455E-07 6,87E-04 ! vasculature development GO:0001944 97 96 7,000 8,77E-07 5,388E-04 ! regulation of cell migration GO:0030334 71 71 6,000 1,431E-06 6,594E-04 ! regulation of locomotion GO:0040012 79 79 6,000 2,967E-06 1,094E-03 ! regulation of cell motion GO:0051270 79 79 6,000 2,967E-06 9,114E-04 ! positive regulation of cell cycle GO:0045787 29 29 4,000 3,048E-06 8,024E-04 ! blood vessel morphogenesis GO:0048514 84 83 6,000 4,145E-06 9,548E-04 ! prostate gland development GO:0030850 5 5 2,000 5,05E-06 1,034E-03 ! positive regulation of cell migration GO:0030335 36 36 4,000 9,265E-06 1,707E-03 ! regulation of embryonic development GO:0045995 6 6 2,000 1,004E-05 1,683E-03 ! lung development GO:0030324 38 37 4,000 1,065E-05 1,635E-03 ! regulation of MAP kinase activity GO:0043405 67 66 5,000 1,379E-05 1,955E-03 ! respiratory tube development GO:0030323 40 39 4,000 1,389E-05 1,828E-03 ! respiratory system development GO:0060541 40 39 4,000 1,389E-05 1,707E-03 ! positive regulation of cell motion GO:0051272 39 39 4,000 1,389E-05 1,6E-03 ! gland development GO:0048732 51 49 4,000 4,324E-05 4,688E-03 ! positive regulation of MAP kinase activity GO:0043406 50 49 4,000 4,324E-05 4,427E-03 ! negative regulation of immune system process GO:0002683 25 25 3,000 4,386E-05 4,254E-03 ! negative regulation of immune response GO:0050777 10 10 2,000 5,888E-05 5,425E-03 ! positive regulation of protein kinase activity GO:0045860 89 86 5,000 6,299E-05 5,528E-03 ! protein amino acid autophosphorylation GO:0046777 28 28 3,000 6,971E-05 5,84E-03 ! positive regulation of transferase activity GO:0051347 91 88 5,000 7,17E-05 5,745E-03 GO:0033674|positive regulation of kinase activity, ! regulation of epithelial cell proliferation GO:0050678 29 29 3,000 8,038E-05 6,173E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 11 11 2,000 8,049E-05 5,934E-03 ! regulation of DNA recombination GO:0000018 13 13 2,000 1,379E-04 9,776E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 13 13 2,000 1,379E-04 9,414E-03 ! positive regulation of epithelial cell proliferation GO:0050679 14 14 2,000 1,745E-04 0,01148635 ! negative regulation of protein kinase activity GO:0006469 37 37 3,000 2,13E-04 0,01353424 ! insulin receptor signaling pathway GO:0008286 17 15 2,000 2,169E-04 0,01332352 ! negative regulation of kinase activity GO:0033673 38 38 3,000 2,366E-04 0,01406538 ! cell-matrix adhesion GO:0007160 39 38 3,000 2,366E-04 0,01362584 ! translational elongation GO:0006414 71 71 4,000 2,577E-04 0,01439253 ! positive regulation of MAPKKK cascade GO:0043410 17 16 2,000 2,654E-04 0,01438562 ! negative regulation of transferase activity GO:0051348 40 40 3,000 2,894E-04 0,01523891 ! cell cycle checkpoint GO:0000075 42 41 3,000 3,188E-04 0,01631847 ! positive regulation of cell adhesion GO:0045785 17 17 2,000 3,204E-04 0,01595946 ! cell junction assembly GO:0034329 18 17 2,000 3,204E-04 0,01553947 ! tissue remodeling GO:0048771 17 17 2,000 3,204E-04 0,01514103 ! cell-substrate adhesion GO:0031589 43 42 3,000 3,502E-04 0,01613489 ! meiosis I GO:0007127 18 18 2,000 3,823E-04 0,01718342 ! epidermal growth factor receptor signaling pathway GO:0007173 18 18 2,000 3,823E-04 0,01677429 ! positive regulation of protein kinase cascade GO:0010740 79 78 4,000 4,002E-04 0,01715211 ! DNA damage checkpoint GO:0000077 19 19 2,000 4,513E-04 0,01890459 ! regulation of DNA binding GO:0051101 47 45 3,000 4,578E-04 0,01874891 ! tube development GO:0035295 83 81 4,000 4,768E-04 0,0191022 ! chromatin remodeling GO:0006338 20 20 2,000 5,279E-04 0,02070126 ! regulation of cell cycle process GO:0010564 50 48 3,000 5,871E-04 0,02254315 ! G1/S transition of mitotic cell cycle GO:0000082 21 21 2,000 6,124E-04 0,02303242 ! DNA integrity checkpoint GO:0031570 21 21 2,000 6,124E-04 0,02257177 ! cellular response to insulin stimulus GO:0032869 23 21 2,000 6,124E-04 0,02212919 ! regulation of anatomical structure morphogenesis GO:0022603 90 86 4,000 6,284E-04 0,02227115 ! positive regulation of glucose metabolic process GO:0010907 5 5 1,000 6,406E-04 0,0222768 ! positive regulation of B cell proliferation GO:0030890 5 5 1,000 6,406E-04 0,02186427 ! mRNA stabilization GO:0048255 5 5 1,000 6,406E-04 0,02146674 GO:0043489|RNA stabilization, ! dopamine receptor signaling pathway GO:0007212 5 5 1,000 6,406E-04 0,0210834 ! endocrine pancreas development GO:0031018 5 5 1,000 6,406E-04 0,02071352 ! thymic T cell selection GO:0045061 5 5 1,000 6,406E-04 0,02035639 ! regulation of phospholipase A2 activity GO:0032429 5 5 1,000 6,406E-04 0,02001137 ! receptor clustering GO:0043113 5 5 1,000 6,406E-04 0,01967784 ! actin cytoskeleton reorganization GO:0031532 5 5 1,000 6,406E-04 0,01935526 ! protein heterooligomerization GO:0051291 5 5 1,000 6,406E-04 0,01904307 ! enucleate erythrocyte differentiation GO:0043353 6 5 1,000 6,406E-04 0,0187408 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 5 5 1,000 6,406E-04 0,01844798 ! postreplication repair GO:0006301 5 5 1,000 6,406E-04 0,01816416 ! positive regulation of immunoglobulin mediated immune response GO:0002891 5 5 1,000 6,406E-04 0,01788895 GO:0002714|positive regulation of B cell mediated immunity, ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 5 5 1,000 6,406E-04 0,01762195 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 5 5 1,000 6,406E-04 0,0173628 GO:0002820|negative regulation of adaptive immune response, ! peptidyl-lysine modification GO:0018205 5 5 1,000 6,406E-04 0,01711117 ! regulation of isotype switching GO:0045191 5 5 1,000 6,406E-04 0,01686672 ! positive regulation of epidermis development GO:0045684 5 5 1,000 6,406E-04 0,01662916 ! dopamine biosynthetic process GO:0042416 5 5 1,000 6,406E-04 0,0163982 ! positive regulation of blood vessel endothelial cell migration GO:0043536 5 5 1,000 6,406E-04 0,01617357 ! B cell receptor signaling pathway GO:0050853 5 5 1,000 6,406E-04 0,01595501 ! heart development GO:0007507 90 87 4,000 6,626E-04 0,01628214 ! regulation of DNA metabolic process GO:0051052 51 50 3,000 6,866E-04 0,01664948 ! positive regulation of DNA metabolic process GO:0051054 23 22 2,000 7,05E-04 0,01687365 ! cell junction organization GO:0034330 23 22 2,000 7,05E-04 0,01665732 ! spindle organization GO:0007051 22 22 2,000 7,05E-04 0,01644647 ! interphase of mitotic cell cycle GO:0051329 52 51 3,000 7,405E-04 0,01705998 GO:0051325|interphase, ! positive regulation of growth GO:0045927 23 23 2,000 8,061E-04 0,01834038 ! DNA replication GO:0006260 91 91 4,000 8,136E-04 0,01828641 ! response to hypoxia GO:0001666 53 53 3,000 8,573E-04 0,01903695 ! glucose homeostasis GO:0042593 24 24 2,000 9,159E-04 0,02009567 GO:0033500|carbohydrate homeostasis, ! androgen receptor signaling pathway GO:0030521 24 24 2,000 9,159E-04 0,01985925 ! protein amino acid dephosphorylation GO:0006470 55 54 3,000 9,204E-04 0,0197235 ! response to oxygen levels GO:0070482 55 54 3,000 9,204E-04 0,01949679 ! N-terminal protein amino acid modification GO:0031365 6 6 1,000 9,559E-04 0,02001991 GO:0018409|peptide or protein amino-terminal blocking, ! virus-host interaction GO:0019048 6 6 1,000 9,559E-04 0,01979496 ! regulation of S phase GO:0033261 6 6 1,000 9,559E-04 0,01957502 ! regulation of B cell proliferation GO:0030888 6 6 1,000 9,559E-04 0,01935991 ! regulation of lipid kinase activity GO:0043550 6 6 1,000 9,559E-04 0,01914947 ! cartilage condensation GO:0001502 7 6 1,000 9,559E-04 0,01894357 ! regulation of positive chemotaxis GO:0050926 6 6 1,000 9,559E-04 0,01874204 GO:0050927|positive regulation of positive chemotaxis, ! positive regulation of transcription factor import into nucleus GO:0042993 6 6 1,000 9,559E-04 0,01854475 ! positive regulation of heart contraction GO:0045823 6 6 1,000 9,559E-04 0,01835158 ! positive regulation of gene expression, epigenetic GO:0045815 6 6 1,000 9,559E-04 0,01816239 ! negative regulation of protein amino acid phosphorylation GO:0001933 6 6 1,000 9,559E-04 0,01797706 ! positive regulation of cell growth GO:0030307 6 6 1,000 9,559E-04 0,01779547 ! telomere maintenance via telomerase GO:0007004 6 6 1,000 9,559E-04 0,01761752 GO:0010833|telomere maintenance via telomere lengthening, ! focal adhesion formation GO:0048041 7 6 1,000 9,559E-04 0,01744309 ! negative regulation of T cell proliferation GO:0042130 6 6 1,000 9,559E-04 0,01727208 GO:0070667|negative regulation of mast cell proliferation, ! regulation of vascular permeability GO:0043114 6 6 1,000 9,559E-04 0,01710439 ! regulation of bone resorption GO:0045124 6 6 1,000 9,559E-04 0,01693992 ! positive regulation of T cell mediated immunity GO:0002711 6 6 1,000 9,559E-04 0,01677859 ! regulation of T cell differentiation in the thymus GO:0033081 6 6 1,000 9,559E-04 0,0166203 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 6 6 1,000 9,559E-04 0,01646497 ! phosphoinositide 3-kinase cascade GO:0014065 6 6 1,000 9,559E-04 0,01631252 ! protein sumoylation GO:0016925 6 6 1,000 9,559E-04 0,01616286 ! salivary gland morphogenesis GO:0007435 6 6 1,000 9,559E-04 0,01601592 ! regulation of cellular carbohydrate catabolic process GO:0043471 6 6 1,000 9,559E-04 0,01587164 GO:0043470|regulation of carbohydrate catabolic process, GO:0006110|regulation of glycolysis, ! negative regulation of immune effector process GO:0002698 6 6 1,000 9,559E-04 0,01572993 ! localization within membrane GO:0051668 6 6 1,000 9,559E-04 0,01559072 ! regulation of cell adhesion GO:0030155 56 55 3,000 9,866E-04 0,01594974 ! regulation of T cell proliferation GO:0042129 25 25 2,000 1,035E-03 0,01658435 ! positive regulation of DNA binding GO:0043388 26 25 2,000 1,035E-03 0,01644138 ! heart morphogenesis GO:0003007 25 25 2,000 1,035E-03 0,01630086 ! reproductive developmental process GO:0003006 56 56 3,000 1,056E-03 0,01649473 ! regulation of binding GO:0051098 60 57 3,000 1,129E-03 0,01748492 ! positive regulation of binding GO:0051099 27 26 2,000 1,163E-03 0,01786317 ! regulation of T cell differentiation GO:0045580 26 26 2,000 1,163E-03 0,01771554 ! response to insulin stimulus GO:0032868 28 26 2,000 1,163E-03 0,01757033 ! hemopoiesis GO:0030097 104 100 4,000 1,246E-03 0,01867135 ! dephosphorylation GO:0016311 60 59 3,000 1,285E-03 0,01910216 ! cell growth GO:0016049 27 27 2,000 1,301E-03 0,01918143 ! positive regulation of cellular catabolic process GO:0031331 7 7 1,000 1,331E-03 0,01947279 ! SMAD protein nuclear translocation GO:0007184 7 7 1,000 1,331E-03 0,01931946 ! cellular protein complex disassembly GO:0043624 8 7 1,000 1,331E-03 0,01916852 GO:0043241|protein complex disassembly, ! hair follicle morphogenesis GO:0031069 7 7 1,000 1,331E-03 0,01901993 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 8 7 1,000 1,331E-03 0,01887362 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 7 7 1,000 1,331E-03 0,01872955 ! negative regulation of lymphocyte proliferation GO:0050672 7 7 1,000 1,331E-03 0,01858766 GO:0032945|negative regulation of mononuclear cell proliferation, GO:0070664|negative regulation of leukocyte proliferation, ! positive regulation of carbohydrate metabolic process GO:0045913 7 7 1,000 1,331E-03 0,0184479 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! NLS-bearing substrate import into nucleus GO:0006607 7 7 1,000 1,331E-03 0,01831023 ! RNA-dependent DNA replication GO:0006278 7 7 1,000 1,331E-03 0,0181746 ! cranial nerve development GO:0021545 7 7 1,000 1,331E-03 0,01804096 ! autonomic nervous system development GO:0048483 7 7 1,000 1,331E-03 0,01790928 ! regulation of macrophage differentiation GO:0045649 8 7 1,000 1,331E-03 0,0177795 ! dopamine metabolic process GO:0042417 7 7 1,000 1,331E-03 0,01765159 ! regulation of mRNA stability GO:0043488 7 7 1,000 1,331E-03 0,01752551 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 7 7 1,000 1,331E-03 0,01740121 ! T cell receptor signaling pathway GO:0050852 7 7 1,000 1,331E-03 0,01727867 ! negative regulation of T cell activation GO:0050868 7 7 1,000 1,331E-03 0,01715784 ! regulation of mast cell proliferation GO:0070666 28 28 2,000 1,449E-03 0,01854154 ! viral reproductive process GO:0022415 29 29 2,000 1,607E-03 0,02042044 ! regulation of lymphocyte proliferation GO:0050670 29 29 2,000 1,607E-03 0,02028057 GO:0032944|regulation of mononuclear cell proliferation, GO:0070663|regulation of leukocyte proliferation, ! response to UV GO:0009411 29 29 2,000 1,607E-03 0,02014261 ! positive regulation of cell killing GO:0031343 8 8 1,000 1,766E-03 0,02198887 ! negative regulation of bone remodeling GO:0046851 8 8 1,000 1,766E-03 0,02184129 ! pancreas development GO:0031016 8 8 1,000 1,766E-03 0,02169568 ! T cell selection GO:0045058 8 8 1,000 1,766E-03 0,021552 ! cell-cell junction assembly GO:0007043 8 8 1,000 1,766E-03 0,02141021 ! positive regulation of endothelial cell migration GO:0010595 8 8 1,000 1,766E-03 0,02127028 ! sex determination GO:0007530 8 8 1,000 1,766E-03 0,02113216 ! positive regulation of myeloid leukocyte differentiation GO:0002763 9 8 1,000 1,766E-03 0,02099582 ! regulation of T cell mediated immunity GO:0002709 8 8 1,000 1,766E-03 0,02086123 ! salivary gland development GO:0007431 8 8 1,000 1,766E-03 0,02072836 ! positive regulation of leukocyte migration GO:0002687 8 8 1,000 1,766E-03 0,02059717 ! regulation of immunoglobulin production GO:0002637 8 8 1,000 1,766E-03 0,02046763 ! catecholamine biosynthetic process GO:0042423 8 8 1,000 1,766E-03 0,0203397 ! regulation of RNA stability GO:0043487 8 8 1,000 1,766E-03 0,02021337 ! regulation of generation of precursor metabolites and energy GO:0043467 8 8 1,000 1,766E-03 0,0200886 ! cytoplasmic sequestering of protein GO:0051220 8 8 1,000 1,766E-03 0,01996535 ! skeletal system morphogenesis GO:0048705 31 30 2,000 1,775E-03 0,01994562 ! striated muscle tissue development GO:0014706 69 67 3,000 2,063E-03 0,02304021 ! negative regulation of cell growth GO:0030308 32 32 2,000 2,144E-03 0,02379813 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 32 32 2,000 2,144E-03 0,02365563 ! regulation of lymphocyte differentiation GO:0045619 32 32 2,000 2,144E-03 0,02351482 ! regulation of cell size GO:0008361 68 68 3,000 2,179E-03 0,02375755 ! positive regulation of cell size GO:0045793 9 9 1,000 2,258E-03 0,02448435 ! negative regulation of cell cycle process GO:0010948 9 9 1,000 2,258E-03 0,02434117 ! regulation of nitric-oxide synthase activity GO:0050999 9 9 1,000 2,258E-03 0,02419965 ! viral genome replication GO:0019079 9 9 1,000 2,258E-03 0,02405977 ! positive regulation of endothelial cell proliferation GO:0001938 9 9 1,000 2,258E-03 0,02392149 ! platelet-derived growth factor receptor signaling pathway GO:0048008 9 9 1,000 2,258E-03 0,0237848 ! regulation of dephosphorylation GO:0035303 9 9 1,000 2,258E-03 0,02364966 ! positive regulation of protein import into nucleus GO:0042307 9 9 1,000 2,258E-03 0,02351604 ! T cell differentiation in the thymus GO:0033077 9 9 1,000 2,258E-03 0,02338393 ! histone acetylation GO:0016573 9 9 1,000 2,258E-03 0,02325329 ! regulation of immunoglobulin mediated immune response GO:0002889 9 9 1,000 2,258E-03 0,02312411 GO:0002712|regulation of B cell mediated immunity, ! negative regulation of tissue remodeling GO:0034104 9 9 1,000 2,258E-03 0,02299635 ! regulation of leukocyte migration GO:0002685 9 9 1,000 2,258E-03 0,02287 ! regulation of leukocyte mediated cytotoxicity GO:0001910 9 9 1,000 2,258E-03 0,02274503 ! regulation of blood vessel endothelial cell migration GO:0043535 9 9 1,000 2,258E-03 0,02262141 ! defense response to virus GO:0051607 9 9 1,000 2,258E-03 0,02249913 ! regulation of mitotic cell cycle GO:0007346 72 69 3,000 2,299E-03 0,02277722 ! negative regulation of cell size GO:0045792 33 33 2,000 2,344E-03 0,02310495 ! muscle tissue development GO:0060537 72 70 3,000 2,423E-03 0,02375745 ! response to peptide hormone stimulus GO:0043434 36 34 2,000 2,556E-03 0,02492906 ! negative regulation of response to stimulus GO:0048585 34 34 2,000 2,556E-03 0,02479785 ! viral reproduction GO:0016032 34 34 2,000 2,556E-03 0,02466802 ! regulation of angiogenesis GO:0045765 35 34 2,000 2,556E-03 0,02453954 ! regulation of bone remodeling GO:0046850 34 34 2,000 2,556E-03 0,02441239 ! regulation of cyclin-dependent protein kinase activity GO:0000079 35 35 2,000 2,78E-03 0,02641122 ! regulation of cell morphogenesis GO:0022604 38 35 2,000 2,78E-03 0,02627578 ! regulation of tissue remodeling GO:0034103 35 35 2,000 2,78E-03 0,02614172 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 10 10 1,000 2,808E-03 0,02627308 ! regulation of glucose metabolic process GO:0010906 10 10 1,000 2,808E-03 0,02614039 ! regulation of cell killing GO:0031341 10 10 1,000 2,808E-03 0,02600903 ! reciprocal meiotic recombination GO:0007131 10 10 1,000 2,808E-03 0,02587899 ! auditory receptor cell differentiation GO:0042491 10 10 1,000 2,808E-03 0,02575024 ! inactivation of MAPK activity GO:0000188 10 10 1,000 2,808E-03 0,02562276 ! epidermis morphogenesis GO:0048730 10 10 1,000 2,808E-03 0,02549654 ! cell-substrate junction assembly GO:0007044 11 10 1,000 2,808E-03 0,02537156 ! exocrine system development GO:0035272 10 10 1,000 2,808E-03 0,02524779 ! neuromuscular junction development GO:0007528 10 10 1,000 2,808E-03 0,02512523 ! regulation of B cell differentiation GO:0045577 10 10 1,000 2,808E-03 0,02500385 ! gland morphogenesis GO:0022612 10 10 1,000 2,808E-03 0,02488364 ! regulation of epidermis development GO:0045682 10 10 1,000 2,808E-03 0,02476458 ! nerve development GO:0021675 10 10 1,000 2,808E-03 0,02464665 ! epithelial to mesenchymal transition GO:0001837 10 10 1,000 2,808E-03 0,02452984 ! positive regulation of neuron apoptosis GO:0043525 10 10 1,000 2,808E-03 0,02441414 ! negative regulation of homeostatic process GO:0032845 10 10 1,000 2,808E-03 0,02429952 ! antigen receptor-mediated signaling pathway GO:0050851 10 10 1,000 2,808E-03 0,02418597 ! protein stabilization GO:0050821 10 10 1,000 2,808E-03 0,02407348 ! regulation of mitosis GO:0007088 37 36 2,000 3,015E-03 0,02572944 GO:0051783|regulation of nuclear division, ! regulation of transcription factor activity GO:0051090 38 37 2,000 3,263E-03 0,02771106 GO:0090046|regulation of transcription regulator activity, ! meiosis GO:0007126 37 37 2,000 3,263E-03 0,02758394 GO:0051327|M phase of meiotic cell cycle, ! negative regulation of growth GO:0045926 37 37 2,000 3,263E-03 0,02745799 ! DNA damage response, signal transduction GO:0042770 37 37 2,000 3,263E-03 0,02733318 ! signal complex assembly GO:0007172 11 11 1,000 3,415E-03 0,02847516 ! protein amino acid acetylation GO:0006473 11 11 1,000 3,415E-03 0,02834689 ! positive regulation of nucleocytoplasmic transport GO:0046824 11 11 1,000 3,415E-03 0,02821978 GO:0032388|positive regulation of intracellular transport, ! T cell proliferation GO:0042098 11 11 1,000 3,415E-03 0,0280938 ! cellular response to starvation GO:0009267 11 11 1,000 3,415E-03 0,02796893 ! cellular macromolecular complex disassembly GO:0034623 12 11 1,000 3,415E-03 0,02784518 ! mitotic spindle organization GO:0007052 11 11 1,000 3,415E-03 0,02772251 ! positive regulation of alpha-beta T cell activation GO:0046635 11 11 1,000 3,415E-03 0,02760092 ! interaction with host GO:0051701 11 11 1,000 3,415E-03 0,02748039 ! regulation of monooxygenase activity GO:0032768 11 11 1,000 3,415E-03 0,02736091 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 11 11 1,000 3,415E-03 0,02724247 ! regulation of cellular carbohydrate metabolic process GO:0010675 11 11 1,000 3,415E-03 0,02712504 GO:0006109|regulation of carbohydrate metabolic process, ! hindbrain development GO:0030902 11 11 1,000 3,415E-03 0,02700863 ! negative regulation of lymphocyte activation GO:0051250 11 11 1,000 3,415E-03 0,02689321 ! urogenital system development GO:0001655 38 38 2,000 3,522E-03 0,02762277 ! meiotic cell cycle GO:0051321 38 38 2,000 3,522E-03 0,02750573 ! steroid hormone receptor signaling pathway GO:0030518 38 38 2,000 3,522E-03 0,02738967 ! regulation of homeostatic process GO:0032844 38 38 2,000 3,522E-03 0,02727459 ! activation of MAPK activity GO:0000187 39 39 2,000 3,794E-03 0,02925545 ! regulation of MAPKKK cascade GO:0043408 41 39 2,000 3,794E-03 0,02913355 ! regulation of alpha-beta T cell activation GO:0046634 12 12 1,000 4,076E-03 0,0311713 ! fibroblast growth factor receptor signaling pathway GO:0008543 12 12 1,000 4,076E-03 0,03104249 ! regulation of chromosome organization GO:0033044 12 12 1,000 4,076E-03 0,03091475 ! somitogenesis GO:0001756 13 12 1,000 4,076E-03 0,03078805 ! G1 phase GO:0051318 13 12 1,000 4,076E-03 0,03066238 ! positive regulation of adaptive immune response GO:0002821 12 12 1,000 4,076E-03 0,03053774 ! neurotransmitter secretion GO:0007269 14 12 1,000 4,076E-03 0,0304141 ! regulation of mitotic metaphase/anaphase transition GO:0030071 13 12 1,000 4,076E-03 0,03029146 ! intracellular receptor-mediated signaling pathway GO:0030522 40 40 2,000 4,078E-03 0,03018366 ! myeloid cell differentiation GO:0030099 42 40 2,000 4,078E-03 0,03006292 ! MAPKKK cascade GO:0000165 82 81 3,000 4,116E-03 0,03022509 ! positive regulation of DNA replication GO:0045740 14 13 1,000 4,792E-03 0,03504738 ! positive regulation of smooth muscle cell proliferation GO:0048661 13 13 1,000 4,792E-03 0,03490886 ! phenol metabolic process GO:0018958 13 13 1,000 4,792E-03 0,03477142 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, GO:0009712|catechol metabolic process, ! G2/M transition of mitotic cell cycle GO:0000086 13 13 1,000 4,792E-03 0,03463506 ! intra-Golgi vesicle-mediated transport GO:0006891 13 13 1,000 4,792E-03 0,03449977 ! negative regulation of protein modification process GO:0031400 13 13 1,000 4,792E-03 0,03436553 ! vasculogenesis GO:0001570 13 13 1,000 4,792E-03 0,03423233 ! receptor metabolic process GO:0043112 14 13 1,000 4,792E-03 0,03410016 ! actin filament bundle formation GO:0051017 13 13 1,000 4,792E-03 0,033969 ! negative regulation of protein catabolic process GO:0042177 13 13 1,000 4,792E-03 0,03383885 ! regulation of endothelial cell migration GO:0010594 13 13 1,000 4,792E-03 0,0337097 ! nucleotide-excision repair, DNA gap filling GO:0006297 13 13 1,000 4,792E-03 0,03358152 ! positive regulation of leukocyte mediated immunity GO:0002705 13 13 1,000 4,792E-03 0,03345432 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 13 13 1,000 4,792E-03 0,03332808 ! positive regulation of locomotion GO:0040017 13 13 1,000 4,792E-03 0,03320279 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, GO:0050920|regulation of chemotaxis, ! neutrophil chemotaxis GO:0030593 14 13 1,000 4,792E-03 0,03307843 ! immunoglobulin production GO:0002377 13 13 1,000 4,792E-03 0,032955 GO:0002440|production of molecular mediator of immune response, ! negative regulation of leukocyte activation GO:0002695 13 13 1,000 4,792E-03 0,03283249 ! cell-cell junction organization GO:0045216 13 13 1,000 4,792E-03 0,03271089 ! telomere organization GO:0032200 13 13 1,000 4,792E-03 0,03259019 GO:0000723|telomere maintenance, ! inner ear receptor cell differentiation GO:0060113 13 13 1,000 4,792E-03 0,03247037 ! protein tetramerization GO:0051262 13 13 1,000 4,792E-03 0,03235143 ! positive regulation of cell differentiation GO:0045597 87 85 3,000 4,891E-03 0,03289787 ! positive regulation of response to stimulus GO:0048584 86 85 3,000 4,891E-03 0,03277824 ! reproductive structure development GO:0048608 43 43 2,000 5,007E-03 0,03343372 ! protein import into nucleus GO:0006606 44 44 2,000 5,343E-03 0,03554627 ! protein amino acid acylation GO:0043543 14 14 1,000 5,562E-03 0,03687168 ! macromolecular complex disassembly GO:0032984 15 14 1,000 5,562E-03 0,03673953 ! calcium-dependent cell-cell adhesion GO:0016339 14 14 1,000 5,562E-03 0,03660831 ! mechanoreceptor differentiation GO:0042490 14 14 1,000 5,562E-03 0,03647804 ! hair cycle GO:0042633 14 14 1,000 5,562E-03 0,03634868 GO:0022404|molting cycle process, GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042303|molting cycle, ! negative regulation of epithelial cell proliferation GO:0050680 14 14 1,000 5,562E-03 0,03622024 ! immune response-activating cell surface receptor signaling pathway GO:0002429 14 14 1,000 5,562E-03 0,0360927 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! response to retinoic acid GO:0032526 14 14 1,000 5,562E-03 0,03596606 GO:0033189|response to vitamin A, ! negative regulation of phosphorus metabolic process GO:0010563 14 14 1,000 5,562E-03 0,03584031 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of behavior GO:0050795 14 14 1,000 5,562E-03 0,03571543 ! collagen fibril organization GO:0030199 14 14 1,000 5,562E-03 0,03559142 ! nuclear import GO:0051170 45 45 2,000 5,691E-03 0,03629537 ! cellular response to hormone stimulus GO:0032870 48 46 2,000 6,054E-03 0,03847275 ! protein import into nucleus, translocation GO:0000060 15 15 1,000 6,384E-03 0,04043233 ! positive regulation of ossification GO:0045778 15 15 1,000 6,384E-03 0,04029386 GO:0046852|positive regulation of bone remodeling, GO:0034105|positive regulation of tissue remodeling, ! response to vitamin GO:0033273 15 15 1,000 6,384E-03 0,04015634 ! regulation of transcription factor import into nucleus GO:0042990 15 15 1,000 6,384E-03 0,04001976 ! striated muscle cell differentiation GO:0051146 16 15 1,000 6,384E-03 0,0398841 ! response to starvation GO:0042594 15 15 1,000 6,384E-03 0,03974935 ! regulation of production of molecular mediator of immune response GO:0002700 15 15 1,000 6,384E-03 0,03961552 ! glutathione metabolic process GO:0006749 16 15 1,000 6,384E-03 0,03948258 ! positive regulation of B cell activation GO:0050871 15 15 1,000 6,384E-03 0,03935053 ! positive regulation of myeloid cell differentiation GO:0045639 16 15 1,000 6,384E-03 0,03921936 ! negative regulation of transcription factor activity GO:0043433 16 15 1,000 6,384E-03 0,03908906 GO:0090048|negative regulation of transcription regulator activity, ! negative regulation of cell activation GO:0050866 15 15 1,000 6,384E-03 0,03895963 ! positive regulation of immune effector process GO:0002699 15 15 1,000 6,384E-03 0,03883105 ! regulation of catabolic process GO:0009894 48 47 2,000 6,43E-03 0,03897951 ! positive regulation of immune system process GO:0002684 92 92 3,000 6,472E-03 0,03910917 ! tissue morphogenesis GO:0048729 94 93 3,000 6,723E-03 0,04049022 ! actin filament organization GO:0007015 50 48 2,000 6,819E-03 0,04093686 ! protein localization in nucleus GO:0034504 48 48 2,000 6,819E-03 0,04080395 ! ossification GO:0001503 50 49 2,000 7,222E-03 0,04307723 GO:0060348|bone development, ! cell cycle arrest GO:0007050 49 49 2,000 7,222E-03 0,04293827 ! skeletal muscle tissue development GO:0007519 50 49 2,000 7,222E-03 0,0428002 GO:0060538|skeletal muscle organ development, ! negative regulation of adenylate cyclase activity GO:0007194 16 16 1,000 7,258E-03 0,04287425 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of mitosis GO:0045840 16 16 1,000 7,258E-03 0,04273727 GO:0051785|positive regulation of nuclear division, ! segmentation GO:0035282 17 16 1,000 7,258E-03 0,04260116 ! positive regulation of cell development GO:0010720 16 16 1,000 7,258E-03 0,04246592 ! regulation of myeloid leukocyte differentiation GO:0002761 17 16 1,000 7,258E-03 0,04233154 ! lymphocyte proliferation GO:0046651 16 16 1,000 7,258E-03 0,042198 ! cellular response to nutrient levels GO:0031669 16 16 1,000 7,258E-03 0,0420653 ! positive regulation of catabolic process GO:0009896 16 16 1,000 7,258E-03 0,04193343 ! regulation of cell morphogenesis involved in differentiation GO:0010769 17 16 1,000 7,258E-03 0,04180239 ! regulation of cell growth GO:0001558 97 96 3,000 7,513E-03 0,04313412 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 50 50 2,000 7,64E-03 0,04372585 ! anterior/posterior pattern formation GO:0009952 51 50 2,000 7,64E-03 0,04359048 ! positive regulation of immune response GO:0050778 51 51 2,000 8,071E-03 0,04590866 ! regulation of smooth muscle cell proliferation GO:0048660 17 17 1,000 8,183E-03 0,04640493 ! myelination GO:0042552 17 17 1,000 8,183E-03 0,04626258 ! leukocyte adhesion GO:0007159 17 17 1,000 8,183E-03 0,0461211 ! glucose transport GO:0015758 17 17 1,000 8,183E-03 0,04598049 ! embryonic skeletal system morphogenesis GO:0048704 17 17 1,000 8,183E-03 0,04584073 ! immune response-activating signal transduction GO:0002757 17 17 1,000 8,183E-03 0,04570182 GO:0002764|immune response-regulating signal transduction, ! regulation of oxidoreductase activity GO:0051341 17 17 1,000 8,183E-03 0,04556375 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 52 52 2,000 8,516E-03 0,04727442 ! response to light stimulus GO:0009416 53 52 2,000 8,516E-03 0,04713245 ! muscle organ development GO:0007517 102 100 3,000 8,658E-03 0,0477769 ! negative regulation of transcription from RNA polymerase II promoter GO:0000122 103 100 3,000 8,658E-03 0,04763428 ! regulation of T cell activation GO:0050863 53 53 2,000 8,976E-03 0,04923217 ! regulation of cellular catabolic process GO:0031329 18 18 1,000 9,158E-03 0,05008527 ! mononuclear cell proliferation GO:0032943 18 18 1,000 9,158E-03 0,04993709 GO:0070661|leukocyte proliferation, ! hexose transport GO:0008645 18 18 1,000 9,158E-03 0,04978978 GO:0015749|monosaccharide transport, ! negative regulation of DNA binding GO:0043392 19 18 1,000 9,158E-03 0,04964334 ! negative regulation of MAP kinase activity GO:0043407 18 18 1,000 9,158E-03 0,04949776 ! cellular response to extracellular stimulus GO:0031668 18 18 1,000 9,158E-03 0,04935303 ! ensheathment of neurons GO:0007272 18 18 1,000 9,158E-03 0,04920914 GO:0008366|axon ensheathment, ! negative regulation of catabolic process GO:0009895 18 18 1,000 9,158E-03 0,04906609 ! symbiosis, encompassing mutualism through parasitism GO:0044403 18 18 1,000 9,158E-03 0,04892387 ! response to virus GO:0009615 54 54 2,000 9,449E-03 0,05033321 ! microtubule cytoskeleton organization GO:0000226 55 55 2,000 9,938E-03 0,05278132 ! regulation of endothelial cell proliferation GO:0001936 19 19 1,000 0,01018264 0,05392704 ! positive regulation of T cell proliferation GO:0042102 19 19 1,000 0,01018264 0,05377252 ! peptidyl-tyrosine phosphorylation GO:0018108 20 19 1,000 0,01018264 0,05361889 ! regulation of lymphocyte mediated immunity GO:0002706 19 19 1,000 0,01018264 0,05346613 ! positive regulation of T cell differentiation GO:0045582 19 19 1,000 0,01018264 0,05331423 ! peripheral nervous system development GO:0007422 19 19 1,000 0,01018264 0,0531632 ! regulation of protein stability GO:0031647 19 19 1,000 0,01018264 0,05301302 ! biogenic amine biosynthetic process GO:0042401 20 19 1,000 0,01018264 0,05286369 ! dorsal/ventral pattern formation GO:0009953 19 19 1,000 0,01018264 0,0527152 ! regulation of cell shape GO:0008360 21 19 1,000 0,01018264 0,05256754 ! extracellular structure organization GO:0043062 56 56 2,000 0,0104404 0,05374763 ! negative regulation of binding GO:0051100 21 20 1,000 0,01125539 0,05778185 ! peptidyl-tyrosine modification GO:0018212 21 20 1,000 0,01125539 0,05762134 ! regulation of B cell activation GO:0050864 20 20 1,000 0,01125539 0,05746173 ! peptidyl-amino acid modification GO:0018193 61 59 2,000 0,01203631 0,06127879 ! protein localization in organelle GO:0033365 59 59 2,000 0,01203631 0,06110998 ! mitotic sister chromatid segregation GO:0000070 21 21 1,000 0,01237571 0,06266052 ! mammary gland development GO:0030879 23 21 1,000 0,01237571 0,06248885 ! regulation of protein import into nucleus GO:0042306 21 21 1,000 0,01237571 0,06231811 ! regulation of leukocyte mediated immunity GO:0002703 21 21 1,000 0,01237571 0,06214831 ! regulation of action potential in neuron GO:0019228 21 21 1,000 0,01237571 0,06197943 ! negative regulation of hydrolase activity GO:0051346 21 21 1,000 0,01237571 0,06181146 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 21 21 1,000 0,01237571 0,0616444 ! negative regulation of protein transport GO:0051224 21 21 1,000 0,01237571 0,06147825 ! regulation of protein amino acid phosphorylation GO:0001932 62 61 2,000 0,01317406 0,06526825 ! positive regulation of transcription factor activity GO:0051091 22 22 1,000 0,01354278 0,06691513 GO:0090047|positive regulation of transcription regulator activity, ! sister chromatid segregation GO:0000819 22 22 1,000 0,01354278 0,06673622 ! positive regulation of lymphocyte proliferation GO:0050671 22 22 1,000 0,01354278 0,06655825 GO:0032946|positive regulation of mononuclear cell proliferation, GO:0070665|positive regulation of leukocyte proliferation, GO:0070668|positive regulation of mast cell proliferation, ! embryonic skeletal system development GO:0048706 22 22 1,000 0,01354278 0,06638124 ! maintenance of protein location in cell GO:0032507 23 22 1,000 0,01354278 0,06620516 ! cell chemotaxis GO:0060326 23 22 1,000 0,01354278 0,06603001 GO:0030595|leukocyte chemotaxis, ! erythrocyte differentiation GO:0030218 23 22 1,000 0,01354278 0,06585579 ! regulation of adaptive immune response GO:0002819 22 22 1,000 0,01354278 0,06568249 ! positive regulation of lymphocyte differentiation GO:0045621 22 22 1,000 0,01354278 0,06551009 ! cytokinesis GO:0000910 23 22 1,000 0,01354278 0,0653386 ! morphogenesis of an epithelium GO:0002009 63 62 2,000 0,01376526 0,06623857 GO:0060429|epithelium development, ! protein import GO:0017038 62 62 2,000 0,01376526 0,06606607 ! regulation of lymphocyte activation GO:0051249 62 62 2,000 0,01376526 0,06589447 ! epithelial cell differentiation GO:0030855 23 23 1,000 0,0147558 0,07045322 ! viral infectious cycle GO:0019058 23 23 1,000 0,0147558 0,07027117 ! mitotic cell cycle checkpoint GO:0007093 24 23 1,000 0,0147558 0,07009006 ! endocrine system development GO:0035270 23 23 1,000 0,0147558 0,06990988 ! calcium-mediated signaling GO:0019722 23 23 1,000 0,0147558 0,06973062 ! cell projection assembly GO:0030031 25 23 1,000 0,0147558 0,06955228 ! positive regulation of cellular component organization GO:0051130 65 65 2,000 0,0156288 0,07347929 ! regulation of action potential GO:0001508 24 24 1,000 0,01601397 0,07509861 ! gliogenesis GO:0042063 24 24 1,000 0,01601397 0,074908 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 26 24 1,000 0,01601397 0,07471836 ! T cell differentiation GO:0030217 24 24 1,000 0,01601397 0,07452968 ! erythrocyte homeostasis GO:0034101 25 24 1,000 0,01601397 0,07434195 ! maintenance of protein location GO:0045185 25 24 1,000 0,01601397 0,07415516 ! negative regulation of protein metabolic process GO:0051248 66 66 2,000 0,01628011 0,07519861 ! regulation of gene-specific transcription GO:0032583 25 25 1,000 0,01731651 0,07978581 ! cellular component disassembly GO:0022411 26 25 1,000 0,01731651 0,07958684 ! endosome transport GO:0016197 25 25 1,000 0,01731651 0,07938886 ! regulation of intracellular protein transport GO:0033157 25 25 1,000 0,01731651 0,07919187 ! generation of a signal involved in cell-cell signaling GO:0003001 27 25 1,000 0,01731651 0,07899585 ! response to radiation GO:0009314 70 68 2,000 0,01762815 0,08021897 ! regionalization GO:0003002 70 69 2,000 0,01832494 0,08318441 ! response to nutrient levels GO:0031667 69 69 2,000 0,01832494 0,08298002 ! regulation of leukocyte activation GO:0002694 69 69 2,000 0,01832494 0,08277664 ! glycolysis GO:0006096 26 26 1,000 0,01866262 0,08409589 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 26 26 1,000 0,01866262 0,08389077 ! maintenance of location in cell GO:0051651 27 26 1,000 0,01866262 0,08368666 ! synapse organization GO:0050808 26 26 1,000 0,01866262 0,08348354 ! wound healing GO:0042060 74 70 2,000 0,01903695 0,08495182 ! growth GO:0040007 70 70 2,000 0,01903695 0,08474662 ! regulation of cell activation GO:0050865 71 71 2,000 0,0197642 0,08777208 ! regulation of nucleocytoplasmic transport GO:0046822 27 27 1,000 0,02005156 0,08883418 ! regulation of neurotransmitter levels GO:0001505 31 27 1,000 0,02005156 0,08862115 ! energy reserve metabolic process GO:0006112 28 27 1,000 0,02005156 0,08840914 ! cAMP-mediated signaling GO:0019933 27 27 1,000 0,02005156 0,08819814 ! peptide metabolic process GO:0006518 29 27 1,000 0,02005156 0,08798814 ! mesenchymal cell development GO:0014031 29 27 1,000 0,02005156 0,08777915 GO:0060485|mesenchyme development, GO:0048762|mesenchymal cell differentiation, ! inner ear development GO:0048839 27 27 1,000 0,02005156 0,08757114 ! sensory organ development GO:0007423 72 72 2,000 0,02050669 0,08934714 ! response to extracellular stimulus GO:0009991 72 72 2,000 0,02050669 0,08913641 ! carbohydrate transport GO:0008643 28 28 1,000 0,02148255 0,09315843 ! histone modification GO:0016570 28 28 1,000 0,02148255 0,09293974 ! cartilage development GO:0051216 29 28 1,000 0,02148255 0,09272209 ! leukocyte migration GO:0050900 30 29 1,000 0,02295484 0,09884525 ! branching morphogenesis of a tube GO:0048754 29 29 1,000 0,02295484 0,09861484 ! DNA-dependent DNA replication GO:0006261 29 29 1,000 0,02295484 0,0983855 ! regulation of gene expression, epigenetic GO:0040029 29 29 1,000 0,02295484 0,09815723 ! covalent chromatin modification GO:0016569 29 29 1,000 0,02295484 0,09793001 ! positive regulation of protein transport GO:0051222 29 29 1,000 0,02295484 0,09770385 ! cell morphogenesis involved in differentiation GO:0000904 82 77 2,000 0,02444838 0,10382113 ! activation of phospholipase C activity GO:0007202 30 30 1,000 0,02446769 0,10366427 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of response to external stimulus GO:0032103 30 30 1,000 0,02446769 0,10342651 ! regulation of ossification GO:0030278 30 30 1,000 0,02446769 0,10318983 ! vascular process in circulatory system GO:0003018 31 30 1,000 0,02446769 0,10295424 ! cellular amino acid derivative biosynthetic process GO:0042398 31 30 1,000 0,02446769 0,10271972 ! establishment of organelle localization GO:0051656 31 30 1,000 0,02446769 0,10248627 ! regulation of protein modification process GO:0031399 79 78 2,000 0,02528259 0,10565942 ! regulation of immune response GO:0050776 78 78 2,000 0,02528259 0,10542037 ! skeletal muscle fiber development GO:0048741 31 31 1,000 0,02602038 0,10825182 ! positive regulation of phospholipase activity GO:0010518 31 31 1,000 0,02602038 0,10800801 ! regulation of DNA replication GO:0006275 32 31 1,000 0,02602038 0,10776529 ! regulation of heart contraction GO:0008016 31 31 1,000 0,02602038 0,10752367 ! extracellular matrix organization GO:0030198 31 31 1,000 0,02602038 0,10728312 ! regulation of intracellular transport GO:0032386 31 31 1,000 0,02602038 0,10704365 ! regulation of myeloid cell differentiation GO:0045637 32 31 1,000 0,02602038 0,10680525 ! nuclear transport GO:0051169 79 79 2,000 0,02613207 0,10702534 GO:0006913|nucleocytoplasmic transport, ! muscle fiber development GO:0048747 32 32 1,000 0,02761217 0,11283642 ! glucose catabolic process GO:0006007 32 32 1,000 0,02761217 0,11258679 ! regulation of phospholipase activity GO:0010517 32 32 1,000 0,02761217 0,11233825 ! cell maturation GO:0048469 32 32 1,000 0,02761217 0,11209081 ! morphogenesis of a branching structure GO:0001763 32 32 1,000 0,02761217 0,11184445 ! positive regulation of lipase activity GO:0060193 32 32 1,000 0,02761217 0,11159918 ! maintenance of location GO:0051235 33 32 1,000 0,02761217 0,11135498 ! regulation of cellular response to stress GO:0080135 35 33 1,000 0,02924235 0,11767173 ! activation of protein kinase activity GO:0032147 35 33 1,000 0,02924235 0,11741537 ! regulation of neuron apoptosis GO:0043523 34 33 1,000 0,02924235 0,11716011 ! cellular amino acid derivative metabolic process GO:0006575 87 84 2,000 0,03060829 0,12236677 ! ear development GO:0043583 34 34 1,000 0,03091022 0,12330635 ! muscle cell differentiation GO:0042692 35 34 1,000 0,03091022 0,12304003 ! regulation of protein catabolic process GO:0042176 35 34 1,000 0,03091022 0,12277485 ! regulation of lipid metabolic process GO:0019216 34 34 1,000 0,03091022 0,12251082 ! positive regulation of phosphorylation GO:0042327 35 35 1,000 0,03261507 0,12899051 ! regulation of immune effector process GO:0002697 35 35 1,000 0,03261507 0,1287143 ! positive regulation of phosphorus metabolic process GO:0010562 36 36 1,000 0,03435622 0,13529598 GO:0045937|positive regulation of phosphate metabolic process, ! positive regulation of organelle organization GO:0010638 36 36 1,000 0,03435622 0,1350075 ! integrin-mediated signaling pathway GO:0007229 36 36 1,000 0,03435622 0,13472025 ! regulation of lipase activity GO:0060191 36 36 1,000 0,03435622 0,13443422 ! activation of immune response GO:0002253 36 36 1,000 0,03435622 0,13414941 ! regulation of adenylate cyclase activity GO:0045761 37 37 1,000 0,03613299 0,1407888 GO:0031279|regulation of cyclase activity, GO:0051339|regulation of lyase activity, ! eye development GO:0001654 37 37 1,000 0,03613299 0,14049178 ! adaptive immune response GO:0002250 37 37 1,000 0,03613299 0,14019601 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! negative regulation of cell cycle GO:0045786 92 91 2,000 0,03751161 0,14523929 ! neurotransmitter transport GO:0006836 40 38 1,000 0,0379447 0,14660815 ! exocytosis GO:0006887 40 38 1,000 0,0379447 0,14630144 ! chromosome segregation GO:0007059 38 38 1,000 0,0379447 0,14599601 ! hexose catabolic process GO:0019320 38 38 1,000 0,0379447 0,14569185 ! axon guidance GO:0007411 39 38 1,000 0,0379447 0,14538896 ! regulation of cAMP biosynthetic process GO:0030817 39 39 1,000 0,0397907 0,15214576 ! nucleotide-excision repair GO:0006289 40 39 1,000 0,0397907 0,15183075 ! cytokine-mediated signaling pathway GO:0019221 39 39 1,000 0,0397907 0,15151705 ! positive regulation of T cell activation GO:0050870 39 39 1,000 0,0397907 0,15120465 ! developmental maturation GO:0021700 39 39 1,000 0,0397907 0,15089353 ! lymphocyte differentiation GO:0030098 39 39 1,000 0,0397907 0,15058368 ! protein oligomerization GO:0051259 39 39 1,000 0,0397907 0,15027511 ! rRNA transcription GO:0009303 5 5 0,000 0,04005198 0,15095255 ! positive regulation of protein ubiquitination GO:0031398 5 5 0,000 0,04005198 0,15064449 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 5 5 0,000 0,04005198 0,15033768 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 5 5 0,000 0,04005198 0,15003211 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! neuron fate specification GO:0048665 5 5 0,000 0,04005198 0,14972779 ! hemoglobin biosynthetic process GO:0042541 5 5 0,000 0,04005198 0,14942469 ! reproductive cellular process GO:0048610 5 5 0,000 0,04005198 0,14912283 ! negative regulation of blood pressure GO:0045776 6 5 0,000 0,04005198 0,14882218 ! metencephalon development GO:0022037 5 5 0,000 0,04005198 0,14852273 ! water transport GO:0006833 5 5 0,000 0,04005198 0,1482245 GO:0042044|fluid transport, ! forebrain regionalization GO:0021871 5 5 0,000 0,04005198 0,14792745 ! DNA synthesis during DNA repair GO:0000731 5 5 0,000 0,04005198 0,1476316 ! glycerol metabolic process GO:0006071 5 5 0,000 0,04005198 0,14733692 ! regulation of cellular amine metabolic process GO:0033238 5 5 0,000 0,04005198 0,14704342 GO:0042053|regulation of dopamine metabolic process, GO:0042069|regulation of catecholamine metabolic process, ! meiotic prophase I GO:0007128 5 5 0,000 0,04005198 0,14675109 GO:0051324|prophase, ! cell volume homeostasis GO:0006884 5 5 0,000 0,04005198 0,14645992 ! regulation of epidermal growth factor receptor activity GO:0007176 5 5 0,000 0,04005198 0,1461699 GO:0010469|regulation of receptor activity, ! regulation of long-term neuronal synaptic plasticity GO:0048169 5 5 0,000 0,04005198 0,14588103 ! filopodium assembly GO:0046847 7 5 0,000 0,04005198 0,14559329 GO:0030035|microspike assembly, ! CTP metabolic process GO:0046036 5 5 0,000 0,04005198 0,14530669 GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0006241|CTP biosynthetic process, ! Golgi to endosome transport GO:0006895 5 5 0,000 0,04005198 0,14502122 ! GTP metabolic process GO:0046039 5 5 0,000 0,04005198 0,14473686 ! establishment of tissue polarity GO:0007164 5 5 0,000 0,04005198 0,14445362 ! positive regulation of cell-cell adhesion GO:0022409 5 5 0,000 0,04005198 0,14417148 ! regulation of neurotransmitter secretion GO:0046928 5 5 0,000 0,04005198 0,14389045 GO:0001956|positive regulation of neurotransmitter secretion, ! neurotransmitter uptake GO:0001504 5 5 0,000 0,04005198 0,1436105 ! social behavior GO:0035176 5 5 0,000 0,04005198 0,14333165 ! macrophage chemotaxis GO:0048246 6 5 0,000 0,04005198 0,14305387 ! 2-oxoglutarate metabolic process GO:0006103 5 5 0,000 0,04005198 0,14277717 ! memory GO:0007613 5 5 0,000 0,04005198 0,14250154 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 5 5 0,000 0,04005198 0,14222697 ! membrane hyperpolarization GO:0060081 5 5 0,000 0,04005198 0,14195346 ! response to lipid GO:0033993 5 5 0,000 0,04005198 0,141681 ! erythrocyte maturation GO:0043249 5 5 0,000 0,04005198 0,14140958 ! hippocampus development GO:0021766 6 5 0,000 0,04005198 0,1411392 ! regulation of carbohydrate biosynthetic process GO:0043255 5 5 0,000 0,04005198 0,14086985 ! glucocorticoid metabolic process GO:0008211 5 5 0,000 0,04005198 0,14060152 ! middle ear morphogenesis GO:0042474 5 5 0,000 0,04005198 0,14033422 ! amyloid precursor protein catabolic process GO:0042987 5 5 0,000 0,04005198 0,14006793 ! mechanosensory behavior GO:0007638 5 5 0,000 0,04005198 0,13980265 ! heart looping GO:0001947 5 5 0,000 0,04005198 0,13953837 ! negative regulation of endocytosis GO:0045806 5 5 0,000 0,04005198 0,13927509 ! response to interferon-gamma GO:0034341 5 5 0,000 0,04005198 0,1390128 ! pseudouridine synthesis GO:0001522 5 5 0,000 0,04005198 0,1387515 ! pH reduction GO:0045851 5 5 0,000 0,04005198 0,13849118 GO:0051452|intracellular pH reduction, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 5 5 0,000 0,04005198 0,13823183 ! lipopolysaccharide metabolic process GO:0008653 5 5 0,000 0,04005198 0,13797346 ! positive regulation of chemokine biosynthetic process GO:0045080 5 5 0,000 0,04005198 0,13771604 ! sphingoid biosynthetic process GO:0046520 5 5 0,000 0,04005198 0,13745959 GO:0046513|ceramide biosynthetic process, ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 5 5 0,000 0,04005198 0,13720409 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! insulin-like growth factor receptor signaling pathway GO:0048009 5 5 0,000 0,04005198 0,13694953 ! photoreceptor cell maintenance GO:0045494 5 5 0,000 0,04005198 0,13669592 ! adrenal gland development GO:0030325 5 5 0,000 0,04005198 0,13644325 ! regulation of cardiac muscle hypertrophy GO:0010611 5 5 0,000 0,04005198 0,13619151 GO:0010612|regulation of cardiac muscle adaptation, GO:0014743|regulation of muscle hypertrophy, GO:0043502|regulation of muscle adaptation, ! melanocyte differentiation GO:0030318 5 5 0,000 0,04005198 0,1359407 GO:0050931|pigment cell differentiation, ! ovulation GO:0030728 5 5 0,000 0,04005198 0,13569081 ! astrocyte differentiation GO:0048708 5 5 0,000 0,04005198 0,13544183 ! mitochondrial respiratory chain complex assembly GO:0033108 5 5 0,000 0,04005198 0,13519377 GO:0032981|mitochondrial respiratory chain complex I assembly, GO:0010257|NADH dehydrogenase complex assembly, ! pituitary gland development GO:0021983 5 5 0,000 0,04005198 0,13494662 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 5 5 0,000 0,04005198 0,13470036 GO:0033135|regulation of peptidyl-serine phosphorylation, ! tyrosine metabolic process GO:0006570 5 5 0,000 0,04005198 0,13445501 ! cytoskeletal anchoring at plasma membrane GO:0007016 6 5 0,000 0,04005198 0,13421054 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 5 5 0,000 0,04005198 0,13396697 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, GO:0009164|nucleoside catabolic process, ! microtubule nucleation GO:0007020 5 5 0,000 0,04005198 0,13372427 ! regulation of interleukin-6 biosynthetic process GO:0045408 5 5 0,000 0,04005198 0,13348246 ! regulation of interleukin-8 biosynthetic process GO:0045414 5 5 0,000 0,04005198 0,13324151 ! indolalkylamine metabolic process GO:0006586 5 5 0,000 0,04005198 0,13300144 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! muscle cell migration GO:0014812 5 5 0,000 0,04005198 0,13276223 ! phasic smooth muscle contraction GO:0014821 5 5 0,000 0,04005198 0,13252388 ! central nervous system neuron axonogenesis GO:0021955 6 5 0,000 0,04005198 0,13228638 GO:0021952|central nervous system projection neuron axonogenesis, ! sister chromatid cohesion GO:0007062 5 5 0,000 0,04005198 0,13204973 ! response to ATP GO:0033198 5 5 0,000 0,04005198 0,13181393 ! regulation of type I interferon production GO:0032479 5 5 0,000 0,04005198 0,13157896 ! regulation of appetite GO:0032098 5 5 0,000 0,04005198 0,13134484 GO:0032095|regulation of response to food, ! vesicle fusion GO:0006906 5 5 0,000 0,04005198 0,13111154 ! paraxial mesoderm development GO:0048339 5 5 0,000 0,04005198 0,13087908 ! regulation of the force of heart contraction GO:0002026 5 5 0,000 0,04005198 0,13064743 ! maintenance of protein location in nucleus GO:0051457 5 5 0,000 0,04005198 0,13041661 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,04005198 0,13018659 ! neurotransmitter biosynthetic process GO:0042136 6 5 0,000 0,04005198 0,12995739 ! fear response GO:0042596 5 5 0,000 0,04005198 0,129729 ! lens development in camera-type eye GO:0002088 5 5 0,000 0,04005198 0,1295014 ! retinol metabolic process GO:0042572 5 5 0,000 0,04005198 0,1292746 ! corticosteroid receptor signaling pathway GO:0031958 5 5 0,000 0,04005198 0,1290486 GO:0042921|glucocorticoid receptor signaling pathway, ! temperature homeostasis GO:0001659 5 5 0,000 0,04005198 0,12882338 ! positive regulation of exocytosis GO:0045921 6 5 0,000 0,04005198 0,12859895 ! parturition GO:0007567 5 5 0,000 0,04005198 0,1283753 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,04005198 0,12815243 ! regulation of vascular endothelial growth factor production GO:0010574 5 5 0,000 0,04005198 0,12793033 ! Schwann cell differentiation GO:0014037 5 5 0,000 0,04005198 0,127709 ! acyl-CoA metabolic process GO:0006637 5 5 0,000 0,04005198 0,12748843 ! wound healing, spreading of epidermal cells GO:0035313 5 5 0,000 0,04005198 0,12726862 ! regulation of gliogenesis GO:0014013 5 5 0,000 0,04005198 0,12704957 GO:0045685|regulation of glial cell differentiation, ! positive regulation of peptide secretion GO:0002793 5 5 0,000 0,04005198 0,12683127 ! response to UV-B GO:0010224 5 5 0,000 0,04005198 0,12661372 ! oligodendrocyte development GO:0014003 5 5 0,000 0,04005198 0,12639692 ! hyaluronan metabolic process GO:0030212 5 5 0,000 0,04005198 0,12618085 ! activated T cell proliferation GO:0050798 5 5 0,000 0,04005198 0,12596553 ! interaction with symbiont GO:0051702 5 5 0,000 0,04005198 0,12575094 ! cellular extravasation GO:0045123 5 5 0,000 0,04005198 0,12553707 ! positive regulation of axonogenesis GO:0050772 5 5 0,000 0,04005198 0,12532394 ! peptidyl-asparagine modification GO:0018196 5 5 0,000 0,04005198 0,12511152 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! positive regulation of phagocytosis GO:0050766 5 5 0,000 0,04005198 0,12489983 ! regulation of insulin receptor signaling pathway GO:0046626 5 5 0,000 0,04005198 0,12468885 ! antigen processing and presentation of exogenous antigen GO:0019884 5 5 0,000 0,04005198 0,12447858 ! response to amine stimulus GO:0014075 5 5 0,000 0,04005198 0,12426902 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 5 5 0,000 0,04005198 0,12406017 ! synaptic vesicle exocytosis GO:0016079 6 5 0,000 0,04005198 0,12385201 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 5 5 0,000 0,04005198 0,12364455 ! glycosylceramide metabolic process GO:0006677 5 5 0,000 0,04005198 0,12343779 ! neuron recognition GO:0008038 5 5 0,000 0,04005198 0,12323172 ! negative regulation of focal adhesion formation GO:0051895 6 5 0,000 0,04005198 0,12302633 ! decidualization GO:0046697 5 5 0,000 0,04005198 0,12282163 ! hair follicle maturation GO:0048820 5 5 0,000 0,04005198 0,12261761 ! phosphatidylinositol biosynthetic process GO:0006661 5 5 0,000 0,04005198 0,12241426 ! regulation of mitochondrial membrane potential GO:0051881 5 5 0,000 0,04005198 0,12221159 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 0,04005198 0,12200959 GO:0009155|purine deoxyribonucleotide catabolic process, ! regulation of interleukin-12 production GO:0032655 5 5 0,000 0,04005198 0,12180825 ! positive regulation of interleukin-6 production GO:0032755 5 5 0,000 0,04005198 0,12160758 ! positive regulation of monooxygenase activity GO:0032770 5 5 0,000 0,04005198 0,12140756 ! spinal cord motor neuron differentiation GO:0021522 5 5 0,000 0,04005198 0,12120821 GO:0021517|ventral spinal cord development, ! cellular pigmentation GO:0033059 5 5 0,000 0,04005198 0,12100951 ! histone methylation GO:0016571 5 5 0,000 0,04005198 0,12081146 ! DNA methylation GO:0006306 5 5 0,000 0,04005198 0,12061405 GO:0006305|DNA alkylation, ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,04005198 0,12041729 ! T cell lineage commitment GO:0002360 5 5 0,000 0,04005198 0,12022117 ! positive regulation of interferon-gamma production GO:0032729 5 5 0,000 0,04005198 0,12002569 ! negative regulation of tumor necrosis factor production GO:0032720 5 5 0,000 0,04005198 0,11983084 ! intracellular cholesterol transport GO:0032367 5 5 0,000 0,04005198 0,11963663 GO:0032366|intracellular sterol transport, ! regulation of mast cell activation GO:0033003 5 5 0,000 0,04005198 0,11944304 ! morphogenesis of a polarized epithelium GO:0001738 5 5 0,000 0,04005198 0,11925008 ! regulation of hormone metabolic process GO:0032350 5 5 0,000 0,04005198 0,11905774 ! regulation of transcription from RNA polymerase III promoter GO:0006359 5 5 0,000 0,04005198 0,11886602 ! regulation of inflammatory response to antigenic stimulus GO:0002861 5 5 0,000 0,04005198 0,11867492 ! sterol catabolic process GO:0016127 5 5 0,000 0,04005198 0,11848443 GO:0006707|cholesterol catabolic process, ! negative regulation of oxidoreductase activity GO:0051354 5 5 0,000 0,04005198 0,11829455 ! detection of biotic stimulus GO:0009595 5 5 0,000 0,04005198 0,11810528 ! regulation of immune response to tumor cell GO:0002837 5 5 0,000 0,04005198 0,11791661 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 5 5 0,000 0,04005198 0,11772855 ! zymogen activation GO:0031638 5 5 0,000 0,04005198 0,11754108 ! positive regulation of interleukin-1 beta secretion GO:0050718 5 5 0,000 0,04005198 0,11735421 ! cellular response to nutrient GO:0031670 5 5 0,000 0,04005198 0,11716794 ! negative regulation of neuroblast proliferation GO:0007406 5 5 0,000 0,04005198 0,11698225 ! peptidyl-histidine modification GO:0018202 5 5 0,000 0,04005198 0,11679715 ! nucleosome positioning GO:0016584 5 5 0,000 0,04005198 0,11661264 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 5 5 0,000 0,04005198 0,11642871 ! negative regulation of neurological system process GO:0031645 5 5 0,000 0,04005198 0,11624535 ! regulation of myoblast differentiation GO:0045661 5 5 0,000 0,04005198 0,11606258 ! glutathione biosynthetic process GO:0006750 5 5 0,000 0,04005198 0,11588038 ! NADPH regeneration GO:0006740 5 5 0,000 0,04005198 0,11569874 GO:0006098|pentose-phosphate shunt, ! positive regulation of erythrocyte differentiation GO:0045648 5 5 0,000 0,04005198 0,11551768 ! positive regulation of leukocyte chemotaxis GO:0002690 5 5 0,000 0,04005198 0,11533719 GO:0002688|regulation of leukocyte chemotaxis, ! musculoskeletal movement GO:0050881 5 5 0,000 0,04005198 0,11515725 GO:0050879|multicellular organismal movement, ! neuromuscular process controlling posture GO:0050884 5 5 0,000 0,04005198 0,11497788 ! sarcomere organization GO:0045214 5 5 0,000 0,04005198 0,11479907 ! regulation of epidermal cell differentiation GO:0045604 5 5 0,000 0,04005198 0,11462081 ! activation of NF-kappaB-inducing kinase activity GO:0007250 5 5 0,000 0,04005198 0,1144431 ! negative regulation of glucose transport GO:0010829 5 5 0,000 0,04005198 0,11426594 GO:0046325|negative regulation of glucose import, ! positive regulation of T-helper cell differentiation GO:0045624 5 5 0,000 0,04005198 0,11408933 GO:0045622|regulation of T-helper cell differentiation, ! oocyte differentiation GO:0009994 5 5 0,000 0,04005198 0,11391327 GO:0048599|oocyte development, ! regulation of protein homodimerization activity GO:0043496 6 5 0,000 0,04005198 0,11373775 ! spleen development GO:0048536 5 5 0,000 0,04005198 0,11356277 ! male genitalia development GO:0030539 5 5 0,000 0,04005198 0,11338832 ! nicotinamide nucleotide biosynthetic process GO:0019359 5 5 0,000 0,04005198 0,11321442 ! quaternary ammonium group transport GO:0015697 5 5 0,000 0,04005198 0,11304104 ! thyroid hormone metabolic process GO:0042403 5 5 0,000 0,04005198 0,11286819 ! leukocyte mediated cytotoxicity GO:0001909 5 5 0,000 0,04005198 0,11269588 ! positive regulation of viral reproduction GO:0048524 5 5 0,000 0,04005198 0,11252408 ! removal of superoxide radicals GO:0019430 6 5 0,000 0,04005198 0,11235281 ! myeloid cell homeostasis GO:0002262 5 5 0,000 0,04005198 0,11218207 ! regulation of fatty acid oxidation GO:0046320 5 5 0,000 0,04005198 0,11201183 ! regulation of Rac protein signal transduction GO:0035020 5 5 0,000 0,04005198 0,11184212 ! ATP catabolic process GO:0006200 5 5 0,000 0,04005198 0,11167292 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,04005198 0,11150423 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 5 5 0,000 0,04005198 0,11133605 ! blastocyst formation GO:0001825 5 5 0,000 0,04005198 0,11116837 ! regulation of fibrinolysis GO:0051917 5 5 0,000 0,04005198 0,1110012 ! embryonic gut development GO:0048566 5 5 0,000 0,04005198 0,11083453 ! negative regulation of organic acid transport GO:0032891 5 5 0,000 0,04005198 0,11066836 ! pyrimidine base metabolic process GO:0006206 5 5 0,000 0,04005198 0,11050269 ! activation of innate immune response GO:0002218 5 5 0,000 0,04005198 0,11033752 GO:0002758|innate immune response-activating signal transduction, ! catecholamine transport GO:0051937 5 5 0,000 0,04005198 0,11017283 ! negative regulation of blood vessel endothelial cell migration GO:0043537 5 5 0,000 0,04005198 0,11000864 ! regulation of NF-kappaB import into nucleus GO:0042345 5 5 0,000 0,04005198 0,10984494 ! muscle adaptation GO:0043500 5 5 0,000 0,04005198 0,10968172 ! positive regulation of actin filament bundle formation GO:0032233 5 5 0,000 0,04005198 0,10951899 ! embryonic heart tube development GO:0035050 5 5 0,000 0,04005198 0,10935674 ! cardiac cell differentiation GO:0035051 6 5 0,000 0,04005198 0,10919497 ! positive regulation of homeostatic process GO:0032846 5 5 0,000 0,04005198 0,10903368 ! defense response to fungus GO:0050832 5 5 0,000 0,04005198 0,10887286 ! lysogeny GO:0030069 5 5 0,000 0,04005198 0,10871252 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 5 5 0,000 0,04005198 0,10855265 ! positive regulation of smooth muscle contraction GO:0045987 5 5 0,000 0,04005198 0,10839324 ! response to nicotine GO:0035094 5 5 0,000 0,04005198 0,10823431 ! establishment of cell polarity GO:0030010 5 5 0,000 0,04005198 0,10807584 ! mitochondrion localization GO:0051646 5 5 0,000 0,04005198 0,10791783 ! nucleus localization GO:0051647 5 5 0,000 0,04005198 0,10776029 ! regulation of synapse structure and activity GO:0050803 5 5 0,000 0,04005198 0,10760321 ! pattern specification process GO:0007389 96 94 2,000 0,04069508 0,10917181 ! epidermis development GO:0008544 94 94 2,000 0,04069508 0,10901313 ! regulation of cAMP metabolic process GO:0030814 40 40 1,000 0,04167031 0,11146355 ! organelle localization GO:0051640 41 40 1,000 0,04167031 0,11130201 ! regulation of nucleotide biosynthetic process GO:0030808 41 41 1,000 0,04358291 0,1162421 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! elevation of cytosolic calcium ion concentration GO:0007204 41 41 1,000 0,04358291 0,11607412 ! monosaccharide catabolic process GO:0046365 41 41 1,000 0,04358291 0,11590663 ! posttranscriptional regulation of gene expression GO:0010608 98 98 2,000 0,04514672 0,1198925 ! blood circulation GO:0008015 99 98 2,000 0,04514672 0,11972 GO:0003013|circulatory system process, ! regulation of cyclic nucleotide metabolic process GO:0030799 42 42 1,000 0,04552783 0,12055718 ! cytosolic calcium ion homeostasis GO:0051480 42 42 1,000 0,04552783 0,12038421 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 42 42 1,000 0,04552783 0,12021174 ! ectoderm development GO:0007398 99 99 2,000 0,04629624 0,12206577 ! response to hormone stimulus GO:0009725 102 100 2,000 0,0474603 0,12495618 ! response to other organism GO:0051707 101 100 2,000 0,0474603 0,12477793 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 43 43 1,000 0,04750446 0,12471614 ! alcohol catabolic process GO:0046164 43 43 1,000 0,04750446 0,12453873 ! homeostasis of number of cells GO:0048872 44 43 1,000 0,04750446 0,12436183 ! regulation of nucleotide metabolic process GO:0006140 43 43 1,000 0,04750446 0,12418543 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 6 6 0,000 0,04787119 0,12496687 ! axon extension GO:0048675 7 6 0,000 0,04787119 0,12479011 ! oligosaccharide biosynthetic process GO:0009312 6 6 0,000 0,04787119 0,12461385 ! tRNA modification GO:0006400 6 6 0,000 0,04787119 0,12443809 ! somatic diversification of immune receptors via somatic mutation GO:0002566 6 6 0,000 0,04787119 0,12426283 GO:0016446|somatic hypermutation of immunoglobulin genes, ! 'de novo' posttranslational protein folding GO:0051084 6 6 0,000 0,04787119 0,12408806 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 6 6 0,000 0,04787119 0,12391378 ! negative regulation of cellular catabolic process GO:0031330 6 6 0,000 0,04787119 0,12373998 ! myotube differentiation GO:0014902 6 6 0,000 0,04787119 0,12356668 ! bone remodeling GO:0046849 6 6 0,000 0,04787119 0,12339386 ! N-glycan processing GO:0006491 6 6 0,000 0,04787119 0,12322152 ! glycosaminoglycan catabolic process GO:0006027 6 6 0,000 0,04787119 0,12304966 ! negative regulation of JAK-STAT cascade GO:0046426 6 6 0,000 0,04787119 0,12287828 ! retina development in camera-type eye GO:0060041 6 6 0,000 0,04787119 0,12270738 ! RNA methylation GO:0001510 6 6 0,000 0,04787119 0,12253696 ! regulation of activated T cell proliferation GO:0046006 6 6 0,000 0,04787119 0,122367 ! succinate metabolic process GO:0006105 7 6 0,000 0,04787119 0,12219752 ! artery development GO:0060840 6 6 0,000 0,04787119 0,1220285 GO:0048844|artery morphogenesis, ! positive regulation of neurotransmitter transport GO:0051590 6 6 0,000 0,04787119 0,12185996 ! bile acid metabolic process GO:0008206 6 6 0,000 0,04787119 0,12169187 ! androgen metabolic process GO:0008209 6 6 0,000 0,04787119 0,12152425 ! estrogen metabolic process GO:0008210 6 6 0,000 0,04787119 0,1213571 ! limbic system development GO:0021761 7 6 0,000 0,04787119 0,1211904 ! cytoplasmic sequestering of transcription factor GO:0042994 6 6 0,000 0,04787119 0,12102415 ! pathogenesis GO:0009405 6 6 0,000 0,04787119 0,12085837 ! ribonucleoside triphosphate catabolic process GO:0009203 6 6 0,000 0,04787119 0,12069304 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! regulation of chemokine biosynthetic process GO:0045073 6 6 0,000 0,04787119 0,12052815 ! nerve growth factor receptor signaling pathway GO:0048011 6 6 0,000 0,04787119 0,12036372 ! inositol phosphate-mediated signaling GO:0048016 6 6 0,000 0,04787119 0,12019974 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 6 6 0,000 0,04787119 0,1200362 ! arginine metabolic process GO:0006525 6 6 0,000 0,04787119 0,11987311 GO:0006527|arginine catabolic process, ! regulation of catecholamine secretion GO:0050433 6 6 0,000 0,04787119 0,11971046 ! oligodendrocyte differentiation GO:0048709 6 6 0,000 0,04787119 0,11954825 ! glutamate catabolic process GO:0006538 7 6 0,000 0,04787119 0,11938648 ! L-phenylalanine metabolic process GO:0006558 6 6 0,000 0,04787119 0,11922515 GO:0006559|L-phenylalanine catabolic process, ! glucan biosynthetic process GO:0009250 6 6 0,000 0,04787119 0,11906425 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 6 6 0,000 0,04787119 0,11890379 ! ER overload response GO:0006983 6 6 0,000 0,04787119 0,11874375 ! V(D)J recombination GO:0033151 6 6 0,000 0,04787119 0,11858415 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 0,04787119 0,11842498 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 6 6 0,000 0,04787119 0,11826623 ! negative regulation of endothelial cell migration GO:0010596 6 6 0,000 0,04787119 0,11810791 ! regulation of heart rate GO:0002027 6 6 0,000 0,04787119 0,11795001 ! lipid digestion GO:0044241 6 6 0,000 0,04787119 0,11779253 ! asymmetric protein localization GO:0008105 6 6 0,000 0,04787119 0,11763548 ! retrograde transport, endosome to Golgi GO:0042147 6 6 0,000 0,04787119 0,11747884 ! phagocytosis, engulfment GO:0006911 6 6 0,000 0,04787119 0,11732262 ! Rac protein signal transduction GO:0016601 6 6 0,000 0,04787119 0,11716681 ! regulation of calcium ion transport into cytosol GO:0010522 6 6 0,000 0,04787119 0,11701142 ! ruffle organization GO:0031529 6 6 0,000 0,04787119 0,11685644 ! peptidyl-serine phosphorylation GO:0018105 6 6 0,000 0,04787119 0,11670186 ! preassembly of GPI anchor in ER membrane GO:0016254 6 6 0,000 0,04787119 0,1165477 ! retinoic acid metabolic process GO:0042573 6 6 0,000 0,04787119 0,11639394 ! neutral amino acid transport GO:0015804 6 6 0,000 0,04787119 0,11624059 ! L-amino acid transport GO:0015807 6 6 0,000 0,04787119 0,11608764 ! bone mineralization GO:0030282 6 6 0,000 0,04787119 0,1159351 GO:0031214|biomineral formation, ! rRNA modification GO:0000154 6 6 0,000 0,04787119 0,11578295 ! negative regulation of ossification GO:0030279 6 6 0,000 0,04787119 0,1156312 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 6 6 0,000 0,04787119 0,11547985 GO:0002717|positive regulation of natural killer cell mediated immunity, GO:0002715|regulation of natural killer cell mediated immunity, GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 7 6 0,000 0,04787119 0,1153289 ! purine base biosynthetic process GO:0009113 6 6 0,000 0,04787119 0,11517834 ! G1 DNA damage checkpoint GO:0031571 6 6 0,000 0,04787119 0,11502817 ! negative regulation of axonogenesis GO:0050771 7 6 0,000 0,04787119 0,1148784 ! regulation of phagocytosis GO:0050764 6 6 0,000 0,04787119 0,11472901 ! regulation of organ growth GO:0046620 6 6 0,000 0,04787119 0,11458001 ! regulation of circadian rhythm GO:0042752 6 6 0,000 0,04787119 0,1144314 ! response to dsRNA GO:0043331 6 6 0,000 0,04787119 0,11428317 ! DNA unwinding during replication GO:0006268 6 6 0,000 0,04787119 0,11413533 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 6 6 0,000 0,04787119 0,11398787 GO:0009147|pyrimidine nucleoside triphosphate metabolic process, ! genitalia development GO:0048806 6 6 0,000 0,04787119 0,11384079 ! sphingomyelin metabolic process GO:0006684 6 6 0,000 0,04787119 0,11369408 ! positive regulation of B cell differentiation GO:0045579 6 6 0,000 0,04787119 0,11354776 ! multicellular organismal aging GO:0010259 6 6 0,000 0,04787119 0,11340181 ! regulation of focal adhesion formation GO:0051893 7 6 0,000 0,04787119 0,11325624 ! respiratory chain complex IV assembly GO:0008535 6 6 0,000 0,04787119 0,11311104 ! erythrocyte development GO:0048821 6 6 0,000 0,04787119 0,11296621 ! renal water homeostasis GO:0003091 6 6 0,000 0,04787119 0,11282175 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 6 6 0,000 0,04787119 0,11267766 GO:0043372|positive regulation of CD4-positive, alpha beta T cell differentiation, ! ribosomal large subunit biogenesis GO:0042273 6 6 0,000 0,04787119 0,11253394 ! regulation of Rho GTPase activity GO:0032319 6 6 0,000 0,04787119 0,11239058 ! ribosome assembly GO:0042255 6 6 0,000 0,04787119 0,11224759 ! positive regulation of Ras GTPase activity GO:0032320 6 6 0,000 0,04787119 0,11210497 ! diencephalon development GO:0021536 6 6 0,000 0,04787119 0,1119627 ! fucose catabolic process GO:0019317 6 6 0,000 0,04787119 0,1118208 GO:0042355|L-fucose catabolic process, ! nitric oxide metabolic process GO:0046209 6 6 0,000 0,04787119 0,11167925 GO:0006809|nitric oxide biosynthetic process, ! regulation of lipid transport GO:0032368 6 6 0,000 0,04787119 0,11153806 ! regulation of cell division GO:0051302 6 6 0,000 0,04787119 0,11139723 ! positive regulation of interleukin-1 secretion GO:0050716 6 6 0,000 0,04787119 0,11125676 ! cellular metabolic compound salvage GO:0043094 6 6 0,000 0,04787119 0,11111664 ! regulation of T-helper 2 type immune response GO:0002828 6 6 0,000 0,04787119 0,11097687 ! neuroblast proliferation GO:0007405 6 6 0,000 0,04787119 0,11083745 ! regulation of interleukin-1 beta secretion GO:0050706 6 6 0,000 0,04787119 0,11069838 ! nitric oxide mediated signal transduction GO:0007263 6 6 0,000 0,04787119 0,11055966 ! regulation of glucose transport GO:0010827 6 6 0,000 0,04787119 0,11042129 GO:0046324|regulation of glucose import, ! intestinal absorption GO:0050892 6 6 0,000 0,04787119 0,11028326 ! methionine biosynthetic process GO:0009086 6 6 0,000 0,04787119 0,11014558 ! glutamine family amino acid biosynthetic process GO:0009084 6 6 0,000 0,04787119 0,11000824 ! serine family amino acid biosynthetic process GO:0009070 6 6 0,000 0,04787119 0,10987124 ! thymus development GO:0048538 6 6 0,000 0,04787119 0,10973459 ! lymph node development GO:0048535 6 6 0,000 0,04787119 0,10959827 ! organic cation transport GO:0015695 6 6 0,000 0,04787119 0,10946229 ! negative regulation of BMP signaling pathway GO:0030514 6 6 0,000 0,04787119 0,10932665 ! regulation of RNA splicing GO:0043484 6 6 0,000 0,04787119 0,10919135 ! positive regulation of JNK cascade GO:0046330 7 6 0,000 0,04787119 0,10905638 ! sperm-egg recognition GO:0035036 7 6 0,000 0,04787119 0,10892174 GO:0007339|binding of sperm to zona pellucida, ! germ cell migration GO:0008354 6 6 0,000 0,04787119 0,10878743 ! establishment or maintenance of apical/basal cell polarity GO:0035088 6 6 0,000 0,04787119 0,10865346 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 6 6 0,000 0,04787119 0,10851981 ! alditol metabolic process GO:0019400 6 6 0,000 0,04787119 0,1083865 ! regulation of synaptic transmission, GABAergic GO:0032228 6 6 0,000 0,04787119 0,10825351 ! regulation of amino acid transport GO:0051955 6 6 0,000 0,04787119 0,10812084 ! maternal placenta development GO:0001893 6 6 0,000 0,04787119 0,10798851 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 45 44 1,000 0,04951217 0,11155371 ! negative regulation of organelle organization GO:0010639 45 44 1,000 0,04951217 0,11141751 ! positive regulation of lymphocyte activation GO:0051251 44 44 1,000 0,04951217 0,11128163 ! amine biosynthetic process GO:0009309 46 45 1,000 0,05155035 0,11572142 ! homophilic cell adhesion GO:0007156 45 45 1,000 0,05155035 0,11558064 ! phosphoinositide-mediated signaling GO:0048015 45 45 1,000 0,05155035 0,11544021 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 46 45 1,000 0,05155035 0,11530011 ! cyclic-nucleotide-mediated signaling GO:0019935 46 46 1,000 0,05361837 0,1197802 ! tube morphogenesis GO:0035239 47 46 1,000 0,05361837 0,11963518 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 47 46 1,000 0,05361837 0,11949052 ! positive regulation of ligase activity GO:0051351 47 46 1,000 0,05361837 0,11934621 ! regulation of membrane potential GO:0042391 46 46 1,000 0,05361837 0,11920225 ! respiratory burst GO:0045730 7 7 0,000 0,05562784 0,12352062 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 7 7 0,000 0,05562784 0,12337198 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 7 7 0,000 0,05562784 0,1232237 ! negative regulation of cell projection organization GO:0031345 8 7 0,000 0,05562784 0,12307577 ! positive regulation of blood pressure GO:0045777 7 7 0,000 0,05562784 0,1229282 ! pteridine and derivative biosynthetic process GO:0042559 7 7 0,000 0,05562784 0,12278098 ! regulation of chemokine production GO:0032642 7 7 0,000 0,05562784 0,12263411 ! double-strand break repair via homologous recombination GO:0000724 7 7 0,000 0,05562784 0,12248759 GO:0000725|recombinational repair, ! positive regulation of GTPase activity GO:0043547 7 7 0,000 0,05562784 0,12234143 ! gene silencing by RNA GO:0031047 7 7 0,000 0,05562784 0,12219561 ! regulation of receptor-mediated endocytosis GO:0048259 7 7 0,000 0,05562784 0,12205014 ! oxaloacetate metabolic process GO:0006107 7 7 0,000 0,05562784 0,12190501 ! regulation of neurotransmitter transport GO:0051588 7 7 0,000 0,05562784 0,12176023 ! keratinocyte proliferation GO:0043616 7 7 0,000 0,05562784 0,12161579 ! axis specification GO:0009798 7 7 0,000 0,05562784 0,1214717 ! negative regulation of muscle cell differentiation GO:0051148 7 7 0,000 0,05562784 0,12132795 ! visual behavior GO:0007632 7 7 0,000 0,05562784 0,12118453 GO:0008542|visual learning, ! startle response GO:0001964 7 7 0,000 0,05562784 0,12104146 ! amyloid precursor protein metabolic process GO:0042982 7 7 0,000 0,05562784 0,12089872 ! positive regulation of lipid metabolic process GO:0045834 7 7 0,000 0,05562784 0,12075632 ! negative regulation of lipid metabolic process GO:0045833 7 7 0,000 0,05562784 0,12061425 ! regulation of interferon-gamma biosynthetic process GO:0045072 7 7 0,000 0,05562784 0,12047252 ! endothelial cell differentiation GO:0045446 7 7 0,000 0,05562784 0,12033112 ! negative regulation of striated muscle development GO:0045843 7 7 0,000 0,05562784 0,12019005 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 7 7 0,000 0,05562784 0,12004931 ! digestive system development GO:0055123 7 7 0,000 0,05562784 0,11990891 GO:0048546|digestive tract morphogenesis, GO:0048547|gut morphogenesis, ! hemoglobin metabolic process GO:0020027 7 7 0,000 0,05562784 0,11976883 ! regulation of exit from mitosis GO:0007096 7 7 0,000 0,05562784 0,11962907 ! protein targeting to ER GO:0045047 8 7 0,000 0,05562784 0,11948964 ! cell differentiation in spinal cord GO:0021515 7 7 0,000 0,05562784 0,11935054 ! endoderm development GO:0007492 7 7 0,000 0,05562784 0,11921176 ! regulation of defense response to virus GO:0050688 7 7 0,000 0,05562784 0,1190733 ! glycolipid biosynthetic process GO:0009247 7 7 0,000 0,05562784 0,11893517 GO:0006688|glycosphingolipid biosynthetic process, ! regulation of mRNA processing GO:0050684 7 7 0,000 0,05562784 0,11879735 ! response to hexose stimulus GO:0009746 7 7 0,000 0,05562784 0,11865986 GO:0034284|response to monosaccharide stimulus, GO:0009749|response to glucose stimulus, ! membrane protein ectodomain proteolysis GO:0006509 7 7 0,000 0,05562784 0,11852268 GO:0033619|membrane protein proteolysis, ! positive regulation of survival gene product expression GO:0045885 7 7 0,000 0,05562784 0,11838581 ! regulation of skeletal muscle fiber development GO:0048742 7 7 0,000 0,05562784 0,11824927 ! cardiac muscle tissue development GO:0048738 7 7 0,000 0,05562784 0,11811304 ! nucleotide-sugar metabolic process GO:0009225 7 7 0,000 0,05562784 0,11797712 ! complement activation, alternative pathway GO:0006957 7 7 0,000 0,05562784 0,11784151 ! arachidonic acid secretion GO:0050482 7 7 0,000 0,05562784 0,11770622 GO:0032309|icosanoid secretion, ! polyamine biosynthetic process GO:0006596 7 7 0,000 0,05562784 0,11757123 ! response to X-ray GO:0010165 7 7 0,000 0,05562784 0,11743656 ! regulation of intracellular pH GO:0051453 7 7 0,000 0,05562784 0,11730219 ! UV protection GO:0009650 7 7 0,000 0,05562784 0,11716813 ! DNA integration GO:0015074 7 7 0,000 0,05562784 0,11703438 ! myofibril assembly GO:0030239 7 7 0,000 0,05562784 0,11690093 GO:0055002|striated muscle cell development, ! positive regulation of muscle contraction GO:0045933 7 7 0,000 0,05562784 0,11676778 ! negative regulation of muscle contraction GO:0045932 7 7 0,000 0,05562784 0,11663494 ! chondroitin sulfate biosynthetic process GO:0030206 7 7 0,000 0,05562784 0,1165024 GO:0030204|chondroitin sulfate metabolic process, ! regulation of exocytosis GO:0017157 8 7 0,000 0,05562784 0,11637016 ! phosphatidylcholine biosynthetic process GO:0006656 7 7 0,000 0,05562784 0,11623823 ! heparan sulfate proteoglycan metabolic process GO:0030201 7 7 0,000 0,05562784 0,11610659 GO:0015012|heparan sulfate proteoglycan biosynthetic process, ! stem cell development GO:0048864 7 7 0,000 0,05562784 0,11597524 GO:0019827|stem cell maintenance, ! alpha-beta T cell differentiation GO:0046632 7 7 0,000 0,05562784 0,1158442 ! negative regulation of myeloid leukocyte differentiation GO:0002762 7 7 0,000 0,05562784 0,11571345 ! axon cargo transport GO:0008088 7 7 0,000 0,05562784 0,11558299 ! eating behavior GO:0042755 7 7 0,000 0,05562784 0,11545283 ! purine nucleoside triphosphate catabolic process GO:0009146 7 7 0,000 0,05562784 0,11532296 ! regulation of interleukin-8 production GO:0032677 7 7 0,000 0,05562784 0,11519339 ! purine ribonucleotide catabolic process GO:0009154 7 7 0,000 0,05562784 0,1150641 ! ribosomal small subunit biogenesis GO:0042274 7 7 0,000 0,05562784 0,11493511 ! protein import into peroxisome matrix GO:0016558 7 7 0,000 0,05562784 0,1148064 ! induction of an organ GO:0001759 7 7 0,000 0,05562784 0,11467798 ! leukocyte activation during immune response GO:0002366 7 7 0,000 0,05562784 0,11454985 GO:0002263|cell activation during immune response, ! response to estradiol stimulus GO:0032355 7 7 0,000 0,05562784 0,114422 ! intracellular lipid transport GO:0032365 7 7 0,000 0,05562784 0,11429444 ! detection of chemical stimulus GO:0009593 8 7 0,000 0,05562784 0,11416717 ! platelet activation GO:0030168 8 7 0,000 0,05562784 0,11404017 ! negative regulation of cytokine secretion GO:0050710 7 7 0,000 0,05562784 0,11391346 ! regulation of interleukin-1 secretion GO:0050704 7 7 0,000 0,05562784 0,11378703 ! natural killer cell activation GO:0030101 7 7 0,000 0,05562784 0,11366088 ! response to gamma radiation GO:0010332 8 7 0,000 0,05562784 0,11353501 ! NADP metabolic process GO:0006739 7 7 0,000 0,05562784 0,11340942 ! neuromuscular synaptic transmission GO:0007274 7 7 0,000 0,05562784 0,1132841 ! synaptic transmission, cholinergic GO:0007271 7 7 0,000 0,05562784 0,11315907 ! ubiquinone metabolic process GO:0006743 7 7 0,000 0,05562784 0,11303431 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, GO:0042375|quinone cofactor metabolic process, ! positive regulation of acute inflammatory response GO:0002675 7 7 0,000 0,05562784 0,11290982 ! regulation of osteoclast differentiation GO:0045670 7 7 0,000 0,05562784 0,1127856 ! negative regulation of cell-substrate adhesion GO:0010812 8 7 0,000 0,05562784 0,11266166 GO:0001953|negative regulation of cell-matrix adhesion, ! multicellular organismal water homeostasis GO:0050891 7 7 0,000 0,05562784 0,112538 ! regulation of ATPase activity GO:0043462 7 7 0,000 0,05562784 0,1124146 ! cell-cell recognition GO:0009988 8 7 0,000 0,05562784 0,11229147 ! hormone catabolic process GO:0042447 7 7 0,000 0,05562784 0,11216862 ! cAMP biosynthetic process GO:0006171 7 7 0,000 0,05562784 0,11204603 ! oxygen transport GO:0015671 7 7 0,000 0,05562784 0,11192371 ! pyridine nucleotide biosynthetic process GO:0019363 7 7 0,000 0,05562784 0,11180165 ! biogenic amine catabolic process GO:0042402 7 7 0,000 0,05562784 0,11167986 ! regulation of axon extension GO:0030516 7 7 0,000 0,05562784 0,11155834 ! cell killing GO:0001906 7 7 0,000 0,05562784 0,11143708 ! adult feeding behavior GO:0008343 7 7 0,000 0,05562784 0,11131609 ! pyrimidine nucleotide catabolic process GO:0006244 7 7 0,000 0,05562784 0,11119535 ! positive regulation of protein polymerization GO:0032273 7 7 0,000 0,05562784 0,11107488 ! response to cold GO:0009409 7 7 0,000 0,05562784 0,11095467 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 47 47 1,000 0,05571565 0,11100967 ! sex differentiation GO:0007548 47 47 1,000 0,05571565 0,11088979 ! calcium ion transport GO:0006816 48 48 1,000 0,05784159 0,11499681 ! regulation of ubiquitin-protein ligase activity GO:0051438 49 48 1,000 0,05784159 0,1148729 ! DNA recombination GO:0006310 48 48 1,000 0,05784159 0,11474924 ! leukocyte differentiation GO:0002521 50 49 1,000 0,0599956 0,1188945 ! divalent metal ion transport GO:0070838 49 49 1,000 0,0599956 0,11876679 ! response to nutrient GO:0007584 49 49 1,000 0,0599956 0,11863936 ! regulation of ligase activity GO:0051340 50 49 1,000 0,0599956 0,1185122 ! positive regulation of cell activation GO:0050867 49 49 1,000 0,0599956 0,11838532 GO:0002696|positive regulation of leukocyte activation, ! negative regulation of transport GO:0051051 51 50 1,000 0,0621771 0,12255871 ! T cell activation GO:0042110 51 50 1,000 0,0621771 0,12242777 ! anatomical structure homeostasis GO:0060249 51 50 1,000 0,0621771 0,12229711 ! regulation of skeletal muscle tissue development GO:0048641 8 8 0,000 0,06332242 0,12441708 ! negative regulation of muscle development GO:0048635 8 8 0,000 0,06332242 0,12428458 ! very-long-chain fatty acid metabolic process GO:0000038 8 8 0,000 0,06332242 0,12415237 ! positive regulation of translation GO:0045727 8 8 0,000 0,06332242 0,12402043 ! superoxide anion generation GO:0042554 8 8 0,000 0,06332242 0,12388877 ! sulfur amino acid biosynthetic process GO:0000097 8 8 0,000 0,06332242 0,1237574 ! cGMP metabolic process GO:0046068 8 8 0,000 0,06332242 0,1236263 GO:0006182|cGMP biosynthetic process, ! thyroid gland development GO:0030878 8 8 0,000 0,06332242 0,12349547 ! 'de novo' protein folding GO:0006458 8 8 0,000 0,06332242 0,12336493 ! dicarboxylic acid transport GO:0006835 8 8 0,000 0,06332242 0,12323466 ! phosphoinositide phosphorylation GO:0046854 8 8 0,000 0,06332242 0,12310467 ! embryonic hindlimb morphogenesis GO:0035116 8 8 0,000 0,06332242 0,12297495 ! zinc ion transport GO:0006829 8 8 0,000 0,06332242 0,1228455 ! embryonic forelimb morphogenesis GO:0035115 8 8 0,000 0,06332242 0,12271632 ! folic acid and derivative biosynthetic process GO:0009396 8 8 0,000 0,06332242 0,12258742 ! regulation of neuronal synaptic plasticity GO:0048168 8 8 0,000 0,06332242 0,12245879 ! cardiac muscle contraction GO:0060048 8 8 0,000 0,06332242 0,12233042 ! lipid localization GO:0010876 8 8 0,000 0,06332242 0,12220233 GO:0019915|lipid storage, ! response to pain GO:0048265 8 8 0,000 0,06332242 0,1220745 ! response to cAMP GO:0051591 8 8 0,000 0,06332242 0,12194694 ! COPI coating of Golgi vesicle GO:0048205 8 8 0,000 0,06332242 0,12181965 GO:0048200|Golgi transport vesicle coating, ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 8 0,000 0,06332242 0,12169262 ! negative regulation of transcription factor import into nucleus GO:0042992 8 8 0,000 0,06332242 0,12156586 ! negative regulation of ion transport GO:0043271 8 8 0,000 0,06332242 0,12143936 ! regulation of response to extracellular stimulus GO:0032104 8 8 0,000 0,06332242 0,12131312 GO:0032107|regulation of response to nutrient levels, ! adult walking behavior GO:0007628 8 8 0,000 0,06332242 0,12118715 ! sensory perception of taste GO:0050909 8 8 0,000 0,06332242 0,12106144 ! organelle fusion GO:0048284 8 8 0,000 0,06332242 0,12093598 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 8 8 0,000 0,06332242 0,12081079 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 8 8 0,000 0,06332242 0,12068586 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 8 8 0,000 0,06332242 0,12056118 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 8 8 0,000 0,06332242 0,12043676 ! sperm motility GO:0030317 8 8 0,000 0,06332242 0,1203126 ! regulation of striated muscle contraction GO:0006942 8 8 0,000 0,06332242 0,1201887 ! DNA duplex unwinding GO:0032508 8 8 0,000 0,06332242 0,12006505 GO:0032392|DNA geometric change, ! glycine metabolic process GO:0006544 8 8 0,000 0,06332242 0,11994165 ! ribonucleotide catabolic process GO:0009261 8 8 0,000 0,06332242 0,1198185 ! negative regulation of microtubule depolymerization GO:0007026 8 8 0,000 0,06332242 0,11969561 GO:0031114|regulation of microtubule depolymerization, ! phosphagen metabolic process GO:0006599 8 8 0,000 0,06332242 0,11957298 GO:0006600|creatine metabolic process, ! polyamine metabolic process GO:0006595 8 8 0,000 0,06332242 0,11945059 ! Golgi organization GO:0007030 8 8 0,000 0,06332242 0,11932845 ! regulation of stress fiber formation GO:0051492 9 8 0,000 0,06332242 0,11920656 ! fructose metabolic process GO:0006000 8 8 0,000 0,06332242 0,11908492 ! mannose metabolic process GO:0006013 9 8 0,000 0,06332242 0,11896353 ! NAD metabolic process GO:0019674 8 8 0,000 0,06332242 0,11884239 ! negative regulation of mitotic cell cycle GO:0045930 9 8 0,000 0,06332242 0,11872149 ! plasma membrane fusion GO:0045026 8 8 0,000 0,06332242 0,11860084 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 8 8 0,000 0,06332242 0,11848043 ! response to fungus GO:0009620 8 8 0,000 0,06332242 0,11836027 ! stem cell differentiation GO:0048863 8 8 0,000 0,06332242 0,11824035 ! alpha-beta T cell activation GO:0046631 8 8 0,000 0,06332242 0,11812067 ! embryonic digit morphogenesis GO:0042733 8 8 0,000 0,06332242 0,11800124 ! regulation of cytokine production during immune response GO:0002718 8 8 0,000 0,06332242 0,11788204 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 0,06332242 0,11776309 ! regulation of vasodilation GO:0042312 8 8 0,000 0,06332242 0,11764438 ! vasoconstriction GO:0042310 8 8 0,000 0,06332242 0,11752591 ! muscle cell development GO:0055001 8 8 0,000 0,06332242 0,11740767 ! nucleoside triphosphate catabolic process GO:0009143 8 8 0,000 0,06332242 0,11728967 ! regulation of fatty acid metabolic process GO:0019217 8 8 0,000 0,06332242 0,11717191 ! sensory perception of pain GO:0019233 8 8 0,000 0,06332242 0,11705439 ! gastrulation with mouth forming second GO:0001702 8 8 0,000 0,06332242 0,1169371 ! immunoglobulin production during immune response GO:0002381 8 8 0,000 0,06332242 0,11682004 GO:0002208|somatic diversification of immunoglobulins during immune response, GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! mRNA cleavage GO:0006379 8 8 0,000 0,06332242 0,11670322 ! chromatin silencing GO:0006342 8 8 0,000 0,06332242 0,11658664 ! tissue regeneration GO:0042246 8 8 0,000 0,06332242 0,11647028 ! negative regulation of blood coagulation GO:0030195 9 8 0,000 0,06332242 0,11635416 ! T cell homeostasis GO:0043029 8 8 0,000 0,06332242 0,11623827 ! peptide biosynthetic process GO:0043043 9 8 0,000 0,06332242 0,11612261 ! peptidyl-serine modification GO:0018209 8 8 0,000 0,06332242 0,11600718 ! water homeostasis GO:0030104 8 8 0,000 0,06332242 0,11589198 ! cofactor transport GO:0051181 8 8 0,000 0,06332242 0,11577701 ! regulation of acute inflammatory response GO:0002673 8 8 0,000 0,06332242 0,11566226 ! acid secretion GO:0046717 8 8 0,000 0,06332242 0,11554775 ! C21-steroid hormone biosynthetic process GO:0006700 8 8 0,000 0,06332242 0,11543346 ! protein-chromophore linkage GO:0018298 9 8 0,000 0,06332242 0,11531939 ! branched chain family amino acid metabolic process GO:0009081 8 8 0,000 0,06332242 0,11520555 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 8 8 0,000 0,06332242 0,11509194 ! aromatic compound biosynthetic process GO:0019438 8 8 0,000 0,06332242 0,11497855 ! release of cytochrome c from mitochondria GO:0001836 9 8 0,000 0,06332242 0,11486538 ! regulation of organic acid transport GO:0032890 8 8 0,000 0,06332242 0,11475243 ! positive regulation of calcium ion transport GO:0051928 8 8 0,000 0,06332242 0,11463971 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 8 8 0,000 0,06332242 0,11452721 ! regulation of multi-organism process GO:0043900 8 8 0,000 0,06332242 0,11441493 ! positive regulation of amine transport GO:0051954 8 8 0,000 0,06332242 0,11430286 ! developmental induction GO:0031128 8 8 0,000 0,06332242 0,11419102 GO:0045168|cell-cell signaling involved in cell fate specification, ! peptide hormone secretion GO:0030072 8 8 0,000 0,06332242 0,1140794 ! positive regulation of calcium-mediated signaling GO:0050850 8 8 0,000 0,06332242 0,11396799 ! actin filament polymerization GO:0030041 9 8 0,000 0,06332242 0,1138568 ! peptide hormone processing GO:0016486 8 8 0,000 0,06332242 0,11374583 ! positive regulation of synaptic transmission GO:0050806 8 8 0,000 0,06332242 0,11363508 ! regulation of steroid biosynthetic process GO:0050810 8 8 0,000 0,06332242 0,11352454 ! biogenic amine metabolic process GO:0006576 52 51 1,000 0,06438552 0,11531828 ! protein modification by small protein conjugation GO:0032446 52 51 1,000 0,06438552 0,11520632 ! cholesterol metabolic process GO:0008203 52 52 1,000 0,0666203 0,11908944 ! carbohydrate catabolic process GO:0016052 53 53 1,000 0,06888087 0,1230111 ! regulation of protein transport GO:0051223 53 53 1,000 0,06888087 0,12289202 GO:0070201|regulation of establishment of protein localization, ! lactation GO:0007595 10 9 0,000 0,07095542 0,12647083 ! embryonic pattern specification GO:0009880 10 9 0,000 0,07095542 0,12634863 ! positive regulation of cell projection organization GO:0031346 9 9 0,000 0,07095542 0,12622667 ! regulation of membrane protein ectodomain proteolysis GO:0051043 9 9 0,000 0,07095542 0,12610495 ! positive regulation of protein complex assembly GO:0031334 9 9 0,000 0,07095542 0,12598346 ! cortical actin cytoskeleton organization GO:0030866 10 9 0,000 0,07095542 0,12586221 ! phospholipid catabolic process GO:0009395 9 9 0,000 0,07095542 0,12574119 ! copper ion transport GO:0006825 9 9 0,000 0,07095542 0,1256204 ! lipid phosphorylation GO:0046834 9 9 0,000 0,07095542 0,12549984 ! aminoglycan catabolic process GO:0006026 9 9 0,000 0,07095542 0,12537952 ! Golgi vesicle budding GO:0048194 9 9 0,000 0,07095542 0,12525942 ! regulation of cell-cell adhesion GO:0022407 9 9 0,000 0,07095542 0,12513955 ! RNA polyadenylation GO:0043631 9 9 0,000 0,07095542 0,12501992 GO:0006378|mRNA polyadenylation, ! gamma-aminobutyric acid signaling pathway GO:0007214 9 9 0,000 0,07095542 0,12490051 ! regulation of postsynaptic membrane potential GO:0060078 9 9 0,000 0,07095542 0,12478133 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 9 9 0,000 0,07095542 0,12466238 ! negative regulation of cytokine biosynthetic process GO:0042036 9 9 0,000 0,07095542 0,12454365 ! phospholipid efflux GO:0033700 9 9 0,000 0,07095542 0,12442515 ! response to alkaloid GO:0043279 10 9 0,000 0,07095542 0,12430688 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 9 9 0,000 0,07095542 0,12418883 ! cytokine biosynthetic process GO:0042089 9 9 0,000 0,07095542 0,124071 GO:0042107|cytokine metabolic process, ! negative regulation of gene expression, epigenetic GO:0045814 9 9 0,000 0,07095542 0,1239534 ! regulation of interleukin-2 biosynthetic process GO:0045076 9 9 0,000 0,07095542 0,12383602 ! response to ethanol GO:0045471 9 9 0,000 0,07095542 0,12371886 ! pyrimidine ribonucleotide metabolic process GO:0009218 9 9 0,000 0,07095542 0,12360192 ! activation of pro-apoptotic gene products GO:0008633 9 9 0,000 0,07095542 0,12348521 ! methionine metabolic process GO:0006555 9 9 0,000 0,07095542 0,12336871 ! glutamine metabolic process GO:0006541 9 9 0,000 0,07095542 0,12325244 ! cerebral cortex development GO:0021987 9 9 0,000 0,07095542 0,12313638 ! response to osmotic stress GO:0006970 9 9 0,000 0,07095542 0,12302054 ! pigmentation during development GO:0048066 9 9 0,000 0,07095542 0,12290492 ! reverse cholesterol transport GO:0043691 9 9 0,000 0,07095542 0,12278952 ! central nervous system neuron development GO:0021954 10 9 0,000 0,07095542 0,12267433 ! pyrimidine ribonucleoside metabolic process GO:0046131 9 9 0,000 0,07095542 0,12255936 ! nucleobase biosynthetic process GO:0046112 9 9 0,000 0,07095542 0,1224446 ! substrate-bound cell migration GO:0006929 9 9 0,000 0,07095542 0,12233006 ! neurotransmitter metabolic process GO:0042133 11 9 0,000 0,07095542 0,12221573 ! negative regulation of caspase activity GO:0043154 9 9 0,000 0,07095542 0,12210162 ! branching involved in ureteric bud morphogenesis GO:0001658 9 9 0,000 0,07095542 0,12198772 GO:0060675|ureteric bud morphogenesis, ! L-glutamate transport GO:0015813 9 9 0,000 0,07095542 0,12187403 GO:0015800|acidic amino acid transport, ! peptide secretion GO:0002790 9 9 0,000 0,07095542 0,12176055 ! cotranslational protein targeting to membrane GO:0006613 10 9 0,000 0,07095542 0,12164729 ! positive regulation of alpha-beta T cell differentiation GO:0046638 9 9 0,000 0,07095542 0,12153423 ! ventricular cardiac muscle morphogenesis GO:0055010 9 9 0,000 0,07095542 0,12142139 ! behavioral interaction between organisms GO:0051705 9 9 0,000 0,07095542 0,12130875 ! negative regulation of protein import into nucleus GO:0042308 9 9 0,000 0,07095542 0,12119632 ! DNA replication initiation GO:0006270 9 9 0,000 0,07095542 0,12108411 ! prostaglandin metabolic process GO:0006693 9 9 0,000 0,07095542 0,12097209 GO:0006692|prostanoid metabolic process, ! regulation of cellular pH GO:0030641 9 9 0,000 0,07095542 0,12086029 ! DNA fragmentation involved in apoptosis GO:0006309 9 9 0,000 0,07095542 0,12074869 ! cellular amino acid derivative catabolic process GO:0042219 10 9 0,000 0,07095542 0,1206373 ! positive regulation of oxidoreductase activity GO:0051353 9 9 0,000 0,07095542 0,12052611 ! positive regulation of cytokine secretion GO:0050715 9 9 0,000 0,07095542 0,12041513 ! negative regulation of inflammatory response GO:0050728 9 9 0,000 0,07095542 0,12030436 ! negative regulation of protein secretion GO:0050709 9 9 0,000 0,07095542 0,12019378 ! positive regulation of transmission of nerve impulse GO:0051971 9 9 0,000 0,07095542 0,12008341 ! collagen catabolic process GO:0030574 9 9 0,000 0,07095542 0,11997324 ! aromatic amino acid family catabolic process GO:0009074 9 9 0,000 0,07095542 0,11986328 ! purine base metabolic process GO:0006144 9 9 0,000 0,07095542 0,11975351 ! gas transport GO:0015669 9 9 0,000 0,07095542 0,11964395 ! cholesterol efflux GO:0033344 9 9 0,000 0,07095542 0,11953458 ! estrogen receptor signaling pathway GO:0030520 9 9 0,000 0,07095542 0,11942542 ! somatic recombination of immunoglobulin gene segments GO:0016447 9 9 0,000 0,07095542 0,11931645 ! regulation of actin filament bundle formation GO:0032231 10 9 0,000 0,07095542 0,11920769 ! regulation of calcium-mediated signaling GO:0050848 9 9 0,000 0,07095542 0,11909912 ! actin filament-based movement GO:0030048 9 9 0,000 0,07095542 0,11899075 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 9 9 0,000 0,07095542 0,11888258 ! hormone metabolic process GO:0042445 55 54 1,000 0,0711667 0,11912827 ! sulfur metabolic process GO:0006790 55 54 1,000 0,0711667 0,11902017 ! negative regulation of multicellular organismal process GO:0051241 55 54 1,000 0,0711667 0,11891226 ! protein modification by small protein conjugation or removal GO:0070647 56 55 1,000 0,07347723 0,12266172 ! regulation of protein localization GO:0032880 58 57 1,000 0,07817026 0,13037809 ! protein import into nucleus, docking GO:0000059 10 10 0,000 0,07852731 0,13085519 ! regulation of protein ubiquitination GO:0031396 10 10 0,000 0,07852731 0,13073698 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 10 10 0,000 0,07852731 0,13061899 ! ER-associated protein catabolic process GO:0030433 10 10 0,000 0,07852731 0,13050121 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! neuron maturation GO:0042551 10 10 0,000 0,07852731 0,13038364 ! pteridine and derivative metabolic process GO:0042558 10 10 0,000 0,07852731 0,13026628 ! positive regulation of anti-apoptosis GO:0045768 10 10 0,000 0,07852731 0,13014914 GO:0045767|regulation of anti-apoptosis, ! cortical cytoskeleton organization GO:0030865 11 10 0,000 0,07852731 0,1300322 ! regulation of lipid biosynthetic process GO:0046890 10 10 0,000 0,07852731 0,12991547 ! hormone secretion GO:0046879 10 10 0,000 0,07852731 0,12979896 ! glucosamine metabolic process GO:0006041 10 10 0,000 0,07852731 0,12968265 GO:0006044|N-acetylglucosamine metabolic process, ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 10 10 0,000 0,07852731 0,12956655 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! negative regulation of nucleocytoplasmic transport GO:0046823 10 10 0,000 0,07852731 0,12945066 ! inositol metabolic process GO:0006020 10 10 0,000 0,07852731 0,12933498 ! cAMP metabolic process GO:0046058 10 10 0,000 0,07852731 0,1292195 ! vesicle targeting, to, from or within Golgi GO:0048199 10 10 0,000 0,07852731 0,12910423 ! transcription from RNA polymerase III promoter GO:0006383 10 10 0,000 0,07852731 0,12898916 ! forelimb morphogenesis GO:0035136 10 10 0,000 0,07852731 0,1288743 ! glial cell development GO:0021782 10 10 0,000 0,07852731 0,12875964 ! phototransduction GO:0007602 11 10 0,000 0,07852731 0,12864519 ! calcium-independent cell-cell adhesion GO:0016338 10 10 0,000 0,07852731 0,12853094 ! apoptotic mitochondrial changes GO:0008637 11 10 0,000 0,07852731 0,12841689 ! fat cell differentiation GO:0045444 10 10 0,000 0,07852731 0,12830305 ! myoblast differentiation GO:0045445 10 10 0,000 0,07852731 0,12818941 ! centrosome cycle GO:0007098 10 10 0,000 0,07852731 0,12807596 ! positive regulation of proteolysis GO:0045862 10 10 0,000 0,07852731 0,12796272 ! response to carbohydrate stimulus GO:0009743 10 10 0,000 0,07852731 0,12784968 ! regulation of survival gene product expression GO:0045884 10 10 0,000 0,07852731 0,12773684 ! induction of apoptosis via death domain receptors GO:0008625 10 10 0,000 0,07852731 0,1276242 ! protein polyubiquitination GO:0000209 10 10 0,000 0,07852731 0,12751175 ! glutamate metabolic process GO:0006536 11 10 0,000 0,07852731 0,12739951 ! plasma membrane organization GO:0007009 10 10 0,000 0,07852731 0,12728746 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 10 10 0,000 0,07852731 0,1271756 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! lysosomal transport GO:0007041 10 10 0,000 0,07852731 0,12706395 ! cellular response to unfolded protein GO:0034620 10 10 0,000 0,07852731 0,12695249 GO:0030968|endoplasmic reticulum unfolded protein response, ! central nervous system neuron differentiation GO:0021953 11 10 0,000 0,07852731 0,12684123 ! purine ribonucleoside metabolic process GO:0046128 10 10 0,000 0,07852731 0,12673016 GO:0042278|purine nucleoside metabolic process, ! vesicle coating GO:0006901 10 10 0,000 0,07852731 0,12661928 ! cell structure disassembly during apoptosis GO:0006921 10 10 0,000 0,07852731 0,1265086 ! embryo implantation GO:0007566 11 10 0,000 0,07852731 0,12639811 ! regulation of protein binding GO:0043393 11 10 0,000 0,07852731 0,12628782 ! protein targeting to peroxisome GO:0006625 10 10 0,000 0,07852731 0,12617771 ! protein targeting to mitochondrion GO:0006626 10 10 0,000 0,07852731 0,1260678 GO:0070585|protein localization in mitochondrion, ! regulation of alpha-beta T cell differentiation GO:0046637 10 10 0,000 0,07852731 0,12595808 ! intermediate filament cytoskeleton organization GO:0045104 10 10 0,000 0,07852731 0,12584856 ! protein export from nucleus GO:0006611 10 10 0,000 0,07852731 0,12573922 ! cytolysis GO:0019835 10 10 0,000 0,07852731 0,12563007 ! positive regulation of biomineral formation GO:0070169 10 10 0,000 0,07852731 0,12552111 GO:0030501|positive regulation of bone mineralization, ! mismatch repair GO:0006298 10 10 0,000 0,07852731 0,12541234 ! histone deacetylation GO:0016575 10 10 0,000 0,07852731 0,12530376 ! mRNA splice site selection GO:0006376 11 10 0,000 0,07852731 0,12519536 ! synaptic vesicle transport GO:0048489 11 10 0,000 0,07852731 0,12508716 ! positive regulation of neurological system process GO:0031646 10 10 0,000 0,07852731 0,12497914 ! sphingolipid biosynthetic process GO:0030148 10 10 0,000 0,07852731 0,1248713 GO:0046467|membrane lipid biosynthetic process, ! sphingolipid catabolic process GO:0030149 10 10 0,000 0,07852731 0,12476365 GO:0046466|membrane lipid catabolic process, ! nerve-nerve synaptic transmission GO:0007270 10 10 0,000 0,07852731 0,12465619 ! regulation of erythrocyte differentiation GO:0045646 10 10 0,000 0,07852731 0,12454891 ! folic acid and derivative metabolic process GO:0006760 10 10 0,000 0,07852731 0,12444182 ! negative regulation of neuron differentiation GO:0045665 10 10 0,000 0,07852731 0,12433491 ! aspartate family amino acid biosynthetic process GO:0009067 10 10 0,000 0,07852731 0,12422819 ! regulation of BMP signaling pathway GO:0030510 10 10 0,000 0,07852731 0,12412165 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 10 10 0,000 0,07852731 0,12401529 ! lymphocyte homeostasis GO:0002260 10 10 0,000 0,07852731 0,12390911 ! gut development GO:0048565 10 10 0,000 0,07852731 0,12380311 ! embryonic organ morphogenesis GO:0048562 10 10 0,000 0,07852731 0,1236973 ! mRNA 3'-end processing GO:0031124 10 10 0,000 0,07852731 0,12359166 ! negative regulation of coagulation GO:0050819 11 10 0,000 0,07852731 0,12348621 ! regulation of cell development GO:0060284 60 59 1,000 0,08295576 0,13033885 ! sterol metabolic process GO:0016125 59 59 1,000 0,08295576 0,13022783 ! cellular aromatic compound metabolic process GO:0006725 60 59 1,000 0,08295576 0,130117 ! immune effector process GO:0002252 59 59 1,000 0,08295576 0,13000635 ! negative regulation of cellular protein metabolic process GO:0032269 60 60 1,000 0,0853819 0,13369485 ! protein polymerization GO:0051258 65 60 1,000 0,0853819 0,13358136 ! protein secretion GO:0009306 11 11 0,000 0,08603859 0,13449459 ! oligosaccharide metabolic process GO:0009311 11 11 0,000 0,08603859 0,13438061 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 11 11 0,000 0,08603859 0,13426683 ! myeloid leukocyte differentiation GO:0002573 12 11 0,000 0,08603859 0,13415323 ! negative regulation of defense response GO:0031348 11 11 0,000 0,08603859 0,13403983 ! G1 phase of mitotic cell cycle GO:0000080 12 11 0,000 0,08603859 0,13392662 ! determination of bilateral symmetry GO:0009855 11 11 0,000 0,08603859 0,1338136 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! positive regulation of hormone secretion GO:0046887 11 11 0,000 0,08603859 0,13370078 ! phosphatidylinositol metabolic process GO:0046488 11 11 0,000 0,08603859 0,13358814 ! skin development GO:0043588 11 11 0,000 0,08603859 0,13347569 ! cellular component assembly involved in morphogenesis GO:0010927 11 11 0,000 0,08603859 0,13336343 ! microtubule-based transport GO:0010970 11 11 0,000 0,08603859 0,13325136 ! endothelial cell migration GO:0043542 11 11 0,000 0,08603859 0,13313948 ! peroxisomal transport GO:0043574 11 11 0,000 0,08603859 0,13302779 ! protein amino acid methylation GO:0006479 11 11 0,000 0,08603859 0,13291628 GO:0008213|protein amino acid alkylation, ! heart contraction GO:0060047 11 11 0,000 0,08603859 0,13280496 GO:0003015|heart process, ! detection of light stimulus involved in sensory perception GO:0050962 12 11 0,000 0,08603859 0,13269383 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 11 11 0,000 0,08603859 0,13258288 ! regulation of transmembrane transporter activity GO:0022898 11 11 0,000 0,08603859 0,13247211 GO:0032412|regulation of ion transmembrane transporter activity, GO:0032409|regulation of transporter activity, ! negative regulation of endothelial cell proliferation GO:0001937 11 11 0,000 0,08603859 0,13236154 ! regulation of viral genome replication GO:0045069 11 11 0,000 0,08603859 0,13225114 ! spinal cord development GO:0021510 11 11 0,000 0,08603859 0,13214093 ! activation of MAPKK activity GO:0000186 12 11 0,000 0,08603859 0,13203091 ! smooth muscle contraction GO:0006939 11 11 0,000 0,08603859 0,13192107 ! digestive system process GO:0022600 11 11 0,000 0,08603859 0,13181141 ! fucose metabolic process GO:0006004 11 11 0,000 0,08603859 0,13170193 ! membrane budding GO:0006900 11 11 0,000 0,08603859 0,13159263 ! apoptotic nuclear changes GO:0030262 11 11 0,000 0,08603859 0,13148352 ! monoamine transport GO:0015844 11 11 0,000 0,08603859 0,13137458 ! regulation of cellular ketone metabolic process GO:0010565 11 11 0,000 0,08603859 0,13126583 ! response to lipopolysaccharide GO:0032496 11 11 0,000 0,08603859 0,13115725 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 11 11 0,000 0,08603859 0,13104886 ! body fluid secretion GO:0007589 11 11 0,000 0,08603859 0,13094065 ! G1/S transition checkpoint GO:0031575 12 11 0,000 0,08603859 0,13083261 ! intermediate filament-based process GO:0045103 11 11 0,000 0,08603859 0,13072475 ! cardiac muscle tissue morphogenesis GO:0055008 11 11 0,000 0,08603859 0,13061707 GO:0060415|muscle tissue morphogenesis, ! membrane depolarization GO:0051899 11 11 0,000 0,08603859 0,13050956 ! regulation of interleukin-2 production GO:0032663 11 11 0,000 0,08603859 0,13040224 ! regulation of ARF GTPase activity GO:0032312 11 11 0,000 0,08603859 0,13029509 ! oogenesis GO:0048477 11 11 0,000 0,08603859 0,13018811 ! negative regulation of angiogenesis GO:0016525 11 11 0,000 0,08603859 0,13008131 ! vitamin transport GO:0051180 11 11 0,000 0,08603859 0,12997469 ! muscle maintenance GO:0046716 12 11 0,000 0,08603859 0,12986824 ! vitamin A metabolic process GO:0006776 11 11 0,000 0,08603859 0,12976197 ! steroid catabolic process GO:0006706 11 11 0,000 0,08603859 0,12965586 ! endocrine process GO:0050886 11 11 0,000 0,08603859 0,12954994 GO:0001990|regulation of systemic arterial blood pressure by hormone, ! aromatic amino acid family metabolic process GO:0009072 11 11 0,000 0,08603859 0,12944418 ! proximal/distal pattern formation GO:0009954 11 11 0,000 0,08603859 0,1293386 ! somatic diversification of immunoglobulins GO:0016445 11 11 0,000 0,08603859 0,12923319 ! RNA 3'-end processing GO:0031123 11 11 0,000 0,08603859 0,12912795 ! proteasomal protein catabolic process GO:0010498 62 61 1,000 0,08782962 0,1317087 GO:0043161|proteasomal ubiquitin-dependent protein catabolic process, ! axonogenesis GO:0007409 66 62 1,000 0,09029844 0,13530083 ! di-, tri-valent inorganic cation transport GO:0015674 63 62 1,000 0,09029844 0,13519092 ! negative regulation of cellular component organization GO:0051129 65 63 1,000 0,09278785 0,1388052 ! glucose metabolic process GO:0006006 63 63 1,000 0,09278785 0,13869262 ! positive regulation of protein catabolic process GO:0045732 12 12 0,000 0,09348972 0,13962849 ! translational initiation GO:0006413 12 12 0,000 0,09348972 0,13951543 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 12 12 0,000 0,09348972 0,13940256 ! positive regulation of angiogenesis GO:0045766 12 12 0,000 0,09348972 0,13928986 ! initiation of viral infection GO:0019059 12 12 0,000 0,09348972 0,13917735 ! DNA catabolic process, endonucleolytic GO:0000737 12 12 0,000 0,09348972 0,13906502 ! iron ion transport GO:0006826 13 12 0,000 0,09348972 0,13895287 ! phosphatidylcholine metabolic process GO:0046470 12 12 0,000 0,09348972 0,1388409 ! amino sugar metabolic process GO:0006040 12 12 0,000 0,09348972 0,13872912 ! post-Golgi vesicle-mediated transport GO:0006892 12 12 0,000 0,09348972 0,13861751 ! protein amino acid ADP-ribosylation GO:0006471 12 12 0,000 0,09348972 0,13850608 ! heterophilic cell adhesion GO:0007157 12 12 0,000 0,09348972 0,13839483 ! collagen metabolic process GO:0032963 12 12 0,000 0,09348972 0,13828376 ! hindlimb morphogenesis GO:0035137 12 12 0,000 0,09348972 0,13817286 ! xenobiotic metabolic process GO:0006805 12 12 0,000 0,09348972 0,13806215 ! glutamate signaling pathway GO:0007215 12 12 0,000 0,09348972 0,13795161 ! C21-steroid hormone metabolic process GO:0008207 13 12 0,000 0,09348972 0,13784125 ! regulation of muscle cell differentiation GO:0051147 13 12 0,000 0,09348972 0,13773106 ! cellular response to hydrogen peroxide GO:0070301 12 12 0,000 0,09348972 0,13762106 GO:0042744|hydrogen peroxide catabolic process, ! negative regulation of peptidase activity GO:0010466 12 12 0,000 0,09348972 0,13751122 ! actomyosin structure organization GO:0031032 12 12 0,000 0,09348972 0,13740156 ! microtubule organizing center organization GO:0031023 12 12 0,000 0,09348972 0,13729208 GO:0051297|centrosome organization, ! positive regulation of endocytosis GO:0045807 12 12 0,000 0,09348972 0,13718277 ! retinoid metabolic process GO:0001523 12 12 0,000 0,09348972 0,13707364 GO:0016101|diterpenoid metabolic process, ! mitotic chromosome condensation GO:0007076 12 12 0,000 0,09348972 0,13696467 ! positive regulation of innate immune response GO:0045089 12 12 0,000 0,09348972 0,13685589 ! GPI anchor biosynthetic process GO:0006506 12 12 0,000 0,09348972 0,13674727 GO:0006505|GPI anchor metabolic process, ! glycoprotein catabolic process GO:0006516 13 12 0,000 0,09348972 0,13663883 ! acute-phase response GO:0006953 12 12 0,000 0,09348972 0,13653056 ! deoxyribonucleotide catabolic process GO:0009264 12 12 0,000 0,09348972 0,13642246 ! vacuolar transport GO:0007034 12 12 0,000 0,09348972 0,13631453 ! polysaccharide catabolic process GO:0000272 12 12 0,000 0,09348972 0,13620677 ! vesicle docking during exocytosis GO:0006904 12 12 0,000 0,09348972 0,13609918 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 12 12 0,000 0,09348972 0,13599176 ! barbed-end actin filament capping GO:0051016 12 12 0,000 0,09348972 0,13588451 GO:0051693|actin filament capping, ! osteoblast differentiation GO:0001649 12 12 0,000 0,09348972 0,13577743 ! male gonad development GO:0008584 12 12 0,000 0,09348972 0,13567052 ! regulation of insulin secretion GO:0050796 12 12 0,000 0,09348972 0,13556378 ! renal system process GO:0003014 12 12 0,000 0,09348972 0,1354572 ! regulation of tumor necrosis factor production GO:0032680 12 12 0,000 0,09348972 0,13535079 ! regulation of steroid metabolic process GO:0019218 12 12 0,000 0,09348972 0,13524455 ! regulation of interleukin-6 production GO:0032675 12 12 0,000 0,09348972 0,13513848 ! pallium development GO:0021543 13 12 0,000 0,09348972 0,13503257 ! cell fate determination GO:0001709 12 12 0,000 0,09348972 0,13492683 ! positive regulation of multicellular organism growth GO:0040018 12 12 0,000 0,09348972 0,13482125 ! regulation of response to biotic stimulus GO:0002831 12 12 0,000 0,09348972 0,13471584 ! detection of light stimulus GO:0009583 13 12 0,000 0,09348972 0,13461059 ! synaptogenesis GO:0007416 12 12 0,000 0,09348972 0,13450551 ! fat-soluble vitamin metabolic process GO:0006775 12 12 0,000 0,09348972 0,13440059 ! hormone transport GO:0009914 12 12 0,000 0,09348972 0,13429584 ! heme biosynthetic process GO:0006783 12 12 0,000 0,09348972 0,13419125 ! spermatid differentiation GO:0048515 13 12 0,000 0,09348972 0,13408682 GO:0007286|spermatid development, ! aromatic compound catabolic process GO:0019439 13 12 0,000 0,09348972 0,13398255 ! pyrimidine nucleotide biosynthetic process GO:0006221 12 12 0,000 0,09348972 0,13387845 ! neural tube closure GO:0001843 13 12 0,000 0,09348972 0,1337745 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! negative regulation of translation GO:0017148 12 12 0,000 0,09348972 0,13367072 ! regulation of microtubule polymerization or depolymerization GO:0031110 12 12 0,000 0,09348972 0,1335671 ! cellular monovalent inorganic cation homeostasis GO:0030004 12 12 0,000 0,09348972 0,13346364 ! regulation of response to external stimulus GO:0032101 65 64 1,000 0,09529737 0,1359389 ! regulation of hormone levels GO:0010817 66 65 1,000 0,09782653 0,13943875 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 13 13 0,000 0,10088119 0,14368163 GO:0016444|somatic cell DNA recombination, ! negative regulation of actin filament polymerization GO:0030837 13 13 0,000 0,10088119 0,14357068 ! gluconeogenesis GO:0006094 13 13 0,000 0,10088119 0,1434599 ! negative regulation of hormone secretion GO:0046888 13 13 0,000 0,10088119 0,14334929 ! 2'-deoxyribonucleotide metabolic process GO:0009394 13 13 0,000 0,10088119 0,14323885 GO:0019692|deoxyribose phosphate metabolic process, ! glycosaminoglycan biosynthetic process GO:0006024 13 13 0,000 0,10088119 0,14312858 ! positive regulation of JAK-STAT cascade GO:0046427 13 13 0,000 0,10088119 0,14301848 ! regeneration GO:0031099 13 13 0,000 0,10088119 0,14290855 ! keratinization GO:0031424 13 13 0,000 0,10088119 0,14279879 ! post-embryonic development GO:0009791 14 13 0,000 0,10088119 0,1426892 ! patterning of blood vessels GO:0001569 13 13 0,000 0,10088119 0,14257978 ! regulation of innate immune response GO:0045088 13 13 0,000 0,10088119 0,14247052 ! mitochondrial membrane organization GO:0007006 13 13 0,000 0,10088119 0,14236143 ! negative regulation of DNA replication GO:0008156 13 13 0,000 0,10088119 0,14225251 ! multicellular organismal macromolecule metabolic process GO:0044259 13 13 0,000 0,10088119 0,14214375 ! response to corticosteroid stimulus GO:0031960 13 13 0,000 0,10088119 0,14203516 GO:0051384|response to glucocorticoid stimulus, ! multicellular organismal catabolic process GO:0044243 13 13 0,000 0,10088119 0,14192674 ! autophagy GO:0006914 13 13 0,000 0,10088119 0,14181848 ! ureteric bud development GO:0001657 13 13 0,000 0,10088119 0,14171039 ! cell aging GO:0007569 13 13 0,000 0,10088119 0,14160246 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 13 13 0,000 0,10088119 0,1414947 ! response to endoplasmic reticulum stress GO:0034976 13 13 0,000 0,10088119 0,14138709 ! coenzyme catabolic process GO:0009109 13 13 0,000 0,10088119 0,14127966 GO:0046356|acetyl-CoA catabolic process, GO:0006099|tricarboxylic acid cycle, ! negative regulation of protein kinase cascade GO:0010741 13 13 0,000 0,10088119 0,14117238 ! purine nucleoside monophosphate metabolic process GO:0009126 13 13 0,000 0,10088119 0,14106527 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of peptide secretion GO:0002791 13 13 0,000 0,10088119 0,14095832 ! regulation of viral reproduction GO:0050792 13 13 0,000 0,10088119 0,14085154 ! nucleobase metabolic process GO:0009112 13 13 0,000 0,10088119 0,14074491 ! regulation of axonogenesis GO:0050770 14 13 0,000 0,10088119 0,14063845 ! positive regulation of neurogenesis GO:0050769 13 13 0,000 0,10088119 0,14053215 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 14 13 0,000 0,10088119 0,140426 ! vasodilation GO:0042311 14 13 0,000 0,10088119 0,14032002 ! glycosphingolipid metabolic process GO:0006687 13 13 0,000 0,10088119 0,1402142 GO:0006664|glycolipid metabolic process, ! neural crest cell migration GO:0001755 14 13 0,000 0,10088119 0,14010854 ! long-chain fatty acid transport GO:0015909 13 13 0,000 0,10088119 0,14000303 ! negative regulation of Wnt receptor signaling pathway GO:0030178 13 13 0,000 0,10088119 0,13989769 ! negative regulation of intracellular transport GO:0032387 13 13 0,000 0,10088119 0,1397925 ! regulation of cell-substrate adhesion GO:0010810 14 13 0,000 0,10088119 0,13968748 GO:0001952|regulation of cell-matrix adhesion, ! negative regulation of myeloid cell differentiation GO:0045638 13 13 0,000 0,10088119 0,1395826 ! response to cytokine stimulus GO:0034097 13 13 0,000 0,10088119 0,13947789 ! activation of JUN kinase activity GO:0007257 13 13 0,000 0,10088119 0,13937334 ! terpenoid metabolic process GO:0006721 13 13 0,000 0,10088119 0,13926894 ! alkene biosynthetic process GO:0043450 13 13 0,000 0,10088119 0,13916469 GO:0019370|leukotriene biosynthetic process, ! purine nucleotide catabolic process GO:0006195 13 13 0,000 0,10088119 0,13906061 ! porphyrin biosynthetic process GO:0006779 13 13 0,000 0,10088119 0,13895667 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of cytokine production GO:0001818 13 13 0,000 0,10088119 0,1388529 ! camera-type eye morphogenesis GO:0048593 13 13 0,000 0,10088119 0,13874928 ! pyrimidine nucleoside metabolic process GO:0006213 13 13 0,000 0,10088119 0,13864581 ! blastocyst development GO:0001824 13 13 0,000 0,10088119 0,1385425 ! water-soluble vitamin biosynthetic process GO:0042364 13 13 0,000 0,10088119 0,13843934 ! regulation of amine transport GO:0051952 13 13 0,000 0,10088119 0,13833633 ! tissue homeostasis GO:0001894 13 13 0,000 0,10088119 0,13823348 GO:0048871|multicellular organismal homeostasis, ! cell morphogenesis involved in neuron differentiation GO:0048667 72 67 1,000 0,10294188 0,14095237 GO:0048812|neuron projection morphogenesis, GO:0048858|cell projection morphogenesis, ! Golgi vesicle transport GO:0048193 67 67 1,000 0,10294188 0,14084773 ! neuron fate commitment GO:0048663 14 14 0,000 0,10821345 0,14795059 ! sulfur amino acid metabolic process GO:0000096 14 14 0,000 0,10821345 0,14784091 ! regulation of interferon-gamma production GO:0032649 14 14 0,000 0,10821345 0,1477314 ! pyruvate metabolic process GO:0006090 14 14 0,000 0,10821345 0,14762205 ! cellular aldehyde metabolic process GO:0006081 14 14 0,000 0,10821345 0,14751286 ! acetyl-CoA metabolic process GO:0006084 14 14 0,000 0,10821345 0,14740384 ! cellular iron ion homeostasis GO:0006879 14 14 0,000 0,10821345 0,14729497 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 14 14 0,000 0,10821345 0,14718627 ! regulation of neuron projection development GO:0010975 15 14 0,000 0,10821345 0,14707772 ! protein amino acid deacetylation GO:0006476 14 14 0,000 0,10821345 0,14696934 ! aminoglycan biosynthetic process GO:0006023 14 14 0,000 0,10821345 0,14686111 ! vesicle docking GO:0048278 14 14 0,000 0,10821345 0,14675305 ! superoxide metabolic process GO:0006801 15 14 0,000 0,10821345 0,14664514 ! isoprenoid biosynthetic process GO:0008299 14 14 0,000 0,10821345 0,14653739 ! multicellular organismal response to stress GO:0033555 14 14 0,000 0,10821345 0,1464298 ! lysosome organization GO:0007040 14 14 0,000 0,10821345 0,14632237 ! actin polymerization or depolymerization GO:0008154 15 14 0,000 0,10821345 0,1462151 ! D-ribose metabolic process GO:0006014 14 14 0,000 0,10821345 0,14610798 ! peptide transport GO:0015833 14 14 0,000 0,10821345 0,14600102 ! primary neural tube formation GO:0014020 15 14 0,000 0,10821345 0,14589421 ! peptide cross-linking GO:0018149 14 14 0,000 0,10821345 0,14578757 ! vitamin biosynthetic process GO:0009110 14 14 0,000 0,10821345 0,14568107 ! base-excision repair GO:0006284 14 14 0,000 0,10821345 0,14557474 ! response to organic cyclic substance GO:0014070 15 14 0,000 0,10821345 0,14546856 ! leukotriene metabolic process GO:0006691 14 14 0,000 0,10821345 0,14536253 ! regulation of vasoconstriction GO:0019229 14 14 0,000 0,10821345 0,14525666 ! formation of primary germ layer GO:0001704 14 14 0,000 0,10821345 0,14515094 GO:0001707|mesoderm formation, ! DNA modification GO:0006304 14 14 0,000 0,10821345 0,14504538 ! proteoglycan biosynthetic process GO:0030166 14 14 0,000 0,10821345 0,14493996 ! regulation of blood coagulation GO:0030193 15 14 0,000 0,10821345 0,14483471 ! positive regulation of inflammatory response GO:0050729 14 14 0,000 0,10821345 0,1447296 ! group transfer coenzyme metabolic process GO:0006752 14 14 0,000 0,10821345 0,14462465 ! positive regulation of osteoblast differentiation GO:0045669 14 14 0,000 0,10821345 0,14451985 ! neuromuscular process controlling balance GO:0050885 14 14 0,000 0,10821345 0,1444152 ! aspartate family amino acid metabolic process GO:0009066 14 14 0,000 0,10821345 0,1443107 ! response to molecule of bacterial origin GO:0002237 14 14 0,000 0,10821345 0,14420636 ! negative regulation of protein polymerization GO:0032272 14 14 0,000 0,10821345 0,14410216 ! positive regulation of transport GO:0051050 71 70 1,000 0,11075059 0,14737425 ! cell part morphogenesis GO:0032990 75 70 1,000 0,11075059 0,14726792 ! calcium ion homeostasis GO:0055074 71 71 1,000 0,11338787 0,15066608 GO:0006874|cellular calcium ion homeostasis, ! negative regulation of signal transduction GO:0009968 71 71 1,000 0,11338787 0,15055753 ! positive regulation of fibroblast proliferation GO:0048146 15 15 0,000 0,11548698 0,15323434 ! negative regulation of actin filament depolymerization GO:0030835 15 15 0,000 0,11548698 0,1531241 ! negative regulation of protein complex assembly GO:0031333 15 15 0,000 0,11548698 0,15301402 ! protein amino acid O-linked glycosylation GO:0006493 15 15 0,000 0,11548698 0,1529041 ! cellular polysaccharide biosynthetic process GO:0033692 15 15 0,000 0,11548698 0,15279433 ! proteoglycan metabolic process GO:0006029 15 15 0,000 0,11548698 0,15268472 ! odontogenesis of dentine-containing tooth GO:0042475 15 15 0,000 0,11548698 0,15257527 ! detection of stimulus involved in sensory perception GO:0050906 16 15 0,000 0,11548698 0,15246598 ! ovarian follicle development GO:0001541 15 15 0,000 0,11548698 0,15235684 ! antigen processing and presentation of peptide antigen GO:0048002 15 15 0,000 0,11548698 0,15224786 ! regulation of smooth muscle contraction GO:0006940 15 15 0,000 0,11548698 0,15213903 ! deoxyribonucleotide metabolic process GO:0009262 15 15 0,000 0,11548698 0,15203036 ! complement activation, classical pathway GO:0006958 15 15 0,000 0,11548698 0,15192184 ! ER-nuclear signaling pathway GO:0006984 15 15 0,000 0,11548698 0,15181348 ! heme metabolic process GO:0042168 15 15 0,000 0,11548698 0,15170528 ! mesoderm morphogenesis GO:0048332 15 15 0,000 0,11548698 0,15159723 ! chromosome condensation GO:0030261 15 15 0,000 0,11548698 0,15148933 ! response to ionizing radiation GO:0010212 16 15 0,000 0,11548698 0,15138158 ! response to mechanical stimulus GO:0009612 15 15 0,000 0,11548698 0,15127399 ! hydrogen peroxide metabolic process GO:0042743 15 15 0,000 0,11548698 0,15116655 ! regulation of biomineral formation GO:0070167 15 15 0,000 0,11548698 0,15105926 GO:0030500|regulation of bone mineralization, ! cyclic nucleotide biosynthetic process GO:0009190 15 15 0,000 0,11548698 0,15095213 ! cholesterol biosynthetic process GO:0006695 15 15 0,000 0,11548698 0,15084515 ! phospholipid transport GO:0015914 15 15 0,000 0,11548698 0,15073832 ! leukocyte homeostasis GO:0001776 15 15 0,000 0,11548698 0,15063164 ! regulation of cytokine secretion GO:0050707 15 15 0,000 0,11548698 0,15052511 ! nicotinamide metabolic process GO:0006769 15 15 0,000 0,11548698 0,15041873 GO:0046496|nicotinamide nucleotide metabolic process, ! cellular alkene metabolic process GO:0043449 15 15 0,000 0,11548698 0,1503125 ! somatic diversification of immune receptors GO:0002200 15 15 0,000 0,11548698 0,15020642 ! protein homooligomerization GO:0051260 15 15 0,000 0,11548698 0,1501005 ! secretion by cell GO:0032940 75 72 1,000 0,11604162 0,15071509 ! positive regulation of hydrolase activity GO:0051345 72 72 1,000 0,11604162 0,15060895 ! regulation of cytokine production GO:0001817 72 72 1,000 0,11604162 0,15050296 ! coenzyme metabolic process GO:0006732 75 74 1,000 0,12139679 0,15733775 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 16 16 0,000 0,12270224 0,15891793 ! alkaloid metabolic process GO:0009820 16 16 0,000 0,12270224 0,15880633 ! regulation of synaptic plasticity GO:0048167 16 16 0,000 0,12270224 0,15869489 ! spliceosomal snRNP biogenesis GO:0000387 16 16 0,000 0,12270224 0,1585836 ! learning GO:0007612 16 16 0,000 0,12270224 0,15847247 ! circadian rhythm GO:0007623 16 16 0,000 0,12270224 0,1583615 ! inner ear morphogenesis GO:0042472 16 16 0,000 0,12270224 0,15825068 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 16 16 0,000 0,12270224 0,15814001 ! vacuole organization GO:0007033 16 16 0,000 0,12270224 0,1580295 ! cellular response to reactive oxygen species GO:0034614 16 16 0,000 0,12270224 0,15791915 ! positive regulation of cytoskeleton organization GO:0051495 16 16 0,000 0,12270224 0,15780895 ! vesicle targeting GO:0006903 17 16 0,000 0,12270224 0,1576989 ! fatty acid beta-oxidation GO:0006635 16 16 0,000 0,12270224 0,157589 ! triglyceride metabolic process GO:0006641 16 16 0,000 0,12270224 0,15747926 ! iron ion homeostasis GO:0055072 16 16 0,000 0,12270224 0,15736967 ! regulation of systemic arterial blood pressure GO:0003073 17 16 0,000 0,12270224 0,15726024 ! cell fate specification GO:0001708 16 16 0,000 0,12270224 0,15715095 ! pentose metabolic process GO:0019321 16 16 0,000 0,12270224 0,15704182 ! fatty acid transport GO:0015908 16 16 0,000 0,12270224 0,15693284 ! regulation of microtubule cytoskeleton organization GO:0070507 16 16 0,000 0,12270224 0,15682401 ! cofactor catabolic process GO:0051187 16 16 0,000 0,12270224 0,15671533 ! ethanolamine and derivative metabolic process GO:0042439 17 16 0,000 0,12270224 0,1566068 ! polyol metabolic process GO:0019751 16 16 0,000 0,12270224 0,15649842 ! serine family amino acid metabolic process GO:0009069 16 16 0,000 0,12270224 0,15639019 ! glutamine family amino acid catabolic process GO:0009065 17 16 0,000 0,12270224 0,15628211 ! porphyrin metabolic process GO:0006778 16 16 0,000 0,12270224 0,15617419 GO:0033013|tetrapyrrole metabolic process, ! embryonic epithelial tube formation GO:0001838 17 16 0,000 0,12270224 0,1560664 GO:0001841|neural tube formation, ! regulation of JUN kinase activity GO:0043506 17 16 0,000 0,12270224 0,15595877 GO:0043507|positive regulation of JUN kinase activity, ! response to xenobiotic stimulus GO:0009410 16 16 0,000 0,12270224 0,15585129 ! regulation of coagulation GO:0050818 17 16 0,000 0,12270224 0,15574395 ! response to oxidative stress GO:0006979 76 75 1,000 0,12409736 0,15740636 ! positive regulation of multicellular organismal process GO:0051240 76 76 1,000 0,12681271 0,16073991 ! negative regulation of cell communication GO:0010648 76 76 1,000 0,12681271 0,16062943 ! cellular metal ion homeostasis GO:0006875 77 77 1,000 0,12954242 0,16397437 ! regulation of fibroblast proliferation GO:0048145 17 17 0,000 0,12985968 0,16426313 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 17 17 0,000 0,12985968 0,16415047 ! regulation of actin filament depolymerization GO:0030834 17 17 0,000 0,12985968 0,16403796 ! phosphoinositide biosynthetic process GO:0046489 17 17 0,000 0,12985968 0,16392561 ! regulation of transmembrane transport GO:0034762 17 17 0,000 0,12985968 0,1638134 ! nucleotide-excision repair, DNA damage removal GO:0000718 18 17 0,000 0,12985968 0,16370136 ! dicarboxylic acid metabolic process GO:0043648 18 17 0,000 0,12985968 0,16358946 ! sensory perception of smell GO:0007608 17 17 0,000 0,12985968 0,16347772 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 17 17 0,000 0,12985968 0,16336613 ! cellular carbohydrate biosynthetic process GO:0034637 17 17 0,000 0,12985968 0,1632547 ! development of primary male sexual characteristics GO:0046546 17 17 0,000 0,12985968 0,16314341 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 17 17 0,000 0,12985968 0,16303228 ! neural crest cell development GO:0014032 19 17 0,000 0,12985968 0,1629213 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 18 17 0,000 0,12985968 0,16281047 ! negative regulation of cell development GO:0010721 18 17 0,000 0,12985968 0,16269978 GO:0050768|negative regulation of neurogenesis, ! cell recognition GO:0008037 18 17 0,000 0,12985968 0,16258926 ! positive regulation of protein secretion GO:0050714 17 17 0,000 0,12985968 0,16247888 ! regulation of osteoblast differentiation GO:0045667 17 17 0,000 0,12985968 0,16236865 ! pyridine nucleotide metabolic process GO:0019362 17 17 0,000 0,12985968 0,16225857 ! pigmentation GO:0043473 17 17 0,000 0,12985968 0,16214863 ! myeloid leukocyte activation GO:0002274 18 17 0,000 0,12985968 0,16203885 ! adult locomotory behavior GO:0008344 17 17 0,000 0,12985968 0,16192922 ! embryonic organ development GO:0048568 17 17 0,000 0,12985968 0,16181973 ! regulation of calcium ion transport GO:0051924 17 17 0,000 0,12985968 0,16171039 ! liver development GO:0001889 17 17 0,000 0,12985968 0,1616012 ! gene silencing GO:0016458 17 17 0,000 0,12985968 0,16149216 ! microtubule-based movement GO:0007018 82 78 1,000 0,1322861 0,16439871 ! metal ion homeostasis GO:0055065 78 78 1,000 0,1322861 0,16428793 ! mRNA export from nucleus GO:0006406 18 18 0,000 0,13695976 0,16997767 ! regulation of cell projection organization GO:0031344 19 18 0,000 0,13695976 0,16986328 ! icosanoid biosynthetic process GO:0046456 18 18 0,000 0,13695976 0,16974905 ! regulation of metal ion transport GO:0010959 18 18 0,000 0,13695976 0,16963497 ! membrane docking GO:0022406 18 18 0,000 0,13695976 0,16952104 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 18 18 0,000 0,13695976 0,16940727 ! response to calcium ion GO:0051592 18 18 0,000 0,13695976 0,16929365 ! negative regulation of response to external stimulus GO:0032102 18 18 0,000 0,13695976 0,16918018 ! cholesterol homeostasis GO:0042632 18 18 0,000 0,13695976 0,16906687 GO:0055092|sterol homeostasis, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 18 18 0,000 0,13695976 0,1689537 ! striated muscle contraction GO:0006941 18 18 0,000 0,13695976 0,16884069 ! neutral lipid metabolic process GO:0006638 18 18 0,000 0,13695976 0,16872783 GO:0006639|acylglycerol metabolic process, ! ceramide metabolic process GO:0006672 18 18 0,000 0,13695976 0,16861512 GO:0046519|sphingoid metabolic process, ! ribonucleoside monophosphate metabolic process GO:0009161 18 18 0,000 0,13695976 0,16850256 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! telencephalon development GO:0021537 19 18 0,000 0,13695976 0,16839015 ! hexose biosynthetic process GO:0019319 18 18 0,000 0,13695976 0,16827789 ! B cell differentiation GO:0030183 18 18 0,000 0,13695976 0,16816578 ! BMP signaling pathway GO:0030509 18 18 0,000 0,13695976 0,16805382 ! regulation of microtubule-based process GO:0032886 18 18 0,000 0,13695976 0,16794201 ! establishment of vesicle localization GO:0051650 19 18 0,000 0,13695976 0,16783034 ! neuron projection development GO:0031175 85 80 1,000 0,13781378 0,16876464 ! lymphocyte activation GO:0046649 82 81 1,000 0,14059699 0,1720586 ! activation of adenylate cyclase activity GO:0007190 19 19 0,000 0,14400293 0,17610976 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 19 19 0,000 0,14400293 0,17599297 GO:0006956|complement activation, ! negative regulation of DNA metabolic process GO:0051053 19 19 0,000 0,14400293 0,17587634 ! glial cell differentiation GO:0010001 19 19 0,000 0,14400293 0,17575987 ! regulation of pH GO:0006885 19 19 0,000 0,14400293 0,17564355 ! regulation of JAK-STAT cascade GO:0046425 19 19 0,000 0,14400293 0,17552738 ! feeding behavior GO:0007631 19 19 0,000 0,14400293 0,17541137 ! peroxisome organization GO:0007031 19 19 0,000 0,14400293 0,17529551 ! regulation of striated muscle tissue development GO:0016202 20 19 0,000 0,14400293 0,1751798 ! multicellular organismal metabolic process GO:0044236 19 19 0,000 0,14400293 0,17506425 ! metanephros development GO:0001656 19 19 0,000 0,14400293 0,17494885 ! ribonucleoside metabolic process GO:0009119 19 19 0,000 0,14400293 0,1748336 ! cellular response to oxidative stress GO:0034599 19 19 0,000 0,14400293 0,1747185 ! nuclear-transcribed mRNA catabolic process GO:0000956 19 19 0,000 0,14400293 0,17460355 ! hormone biosynthetic process GO:0042446 19 19 0,000 0,14400293 0,17448876 ! eye morphogenesis GO:0048592 19 19 0,000 0,14400293 0,17437411 ! placenta development GO:0001890 19 19 0,000 0,14400293 0,17425962 ! response to heat GO:0009408 19 19 0,000 0,14400293 0,17414528 ! vesicle localization GO:0051648 20 19 0,000 0,14400293 0,17403108 ! regulation of muscle development GO:0048634 21 20 0,000 0,15098964 0,18235512 ! negative regulation of cell adhesion GO:0007162 21 20 0,000 0,15098964 0,1822357 ! establishment or maintenance of cell polarity GO:0007163 21 20 0,000 0,15098964 0,18211644 ! organic ether metabolic process GO:0018904 20 20 0,000 0,15098964 0,18199733 GO:0006662|glycerol ether metabolic process, ! cytoskeleton-dependent intracellular transport GO:0030705 20 20 0,000 0,15098964 0,18187837 ! neural tube development GO:0021915 21 20 0,000 0,15098964 0,18175958 ! nucleus organization GO:0006997 20 20 0,000 0,15098964 0,18164094 ! phagocytosis GO:0006909 21 20 0,000 0,15098964 0,18152245 ! positive regulation of gene-specific transcription GO:0043193 20 20 0,000 0,15098964 0,18140412 ! unsaturated fatty acid biosynthetic process GO:0006636 20 20 0,000 0,15098964 0,18128594 ! protein targeting to membrane GO:0006612 22 20 0,000 0,15098964 0,18116791 ! cyclic nucleotide metabolic process GO:0009187 20 20 0,000 0,15098964 0,18105004 ! detection of abiotic stimulus GO:0009582 21 20 0,000 0,15098964 0,18093232 ! lipid oxidation GO:0034440 20 20 0,000 0,15098964 0,18081476 GO:0019395|fatty acid oxidation, ! female gamete generation GO:0007292 20 20 0,000 0,15098964 0,18069735 ! negative regulation of neuron apoptosis GO:0043524 21 20 0,000 0,15098964 0,18058009 ! monosaccharide biosynthetic process GO:0046364 20 20 0,000 0,15098964 0,18046298 ! RNA modification GO:0009451 20 20 0,000 0,15098964 0,18034602 ! single fertilization GO:0007338 21 20 0,000 0,15098964 0,18022922 ! regulation of cellular localization GO:0060341 86 85 1,000 0,1518502 0,1811391 ! nitrogen compound biosynthetic process GO:0044271 86 85 1,000 0,1518502 0,18102193 ! hexose metabolic process GO:0019318 87 86 1,000 0,15469174 0,18429016 ! mRNA catabolic process GO:0006402 21 21 0,000 0,15792034 0,18801498 ! positive regulation of adenylate cyclase activity GO:0045762 21 21 0,000 0,15792034 0,1878936 GO:0051349|positive regulation of lyase activity, GO:0031281|positive regulation of cyclase activity, ! protein amino acid lipidation GO:0006497 21 21 0,000 0,15792034 0,18777238 ! receptor-mediated endocytosis GO:0006898 21 21 0,000 0,15792034 0,18765131 ! Notch signaling pathway GO:0007219 22 21 0,000 0,15792034 0,1875304 ! morphogenesis of embryonic epithelium GO:0016331 22 21 0,000 0,15792034 0,18740965 ! ear morphogenesis GO:0042471 21 21 0,000 0,15792034 0,18728905 ! organic anion transport GO:0015711 21 21 0,000 0,15792034 0,18716861 ! cholesterol transport GO:0030301 21 21 0,000 0,15792034 0,18704832 GO:0015918|sterol transport, ! spliceosome assembly GO:0000245 22 21 0,000 0,15792034 0,18692819 ! regulation of Rab protein signal transduction GO:0032483 21 21 0,000 0,15792034 0,18680821 GO:0032313|regulation of Rab GTPase activity, ! regulation of multicellular organism growth GO:0040014 21 21 0,000 0,15792034 0,18668838 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 21 21 0,000 0,15792034 0,18656871 ! regulation of proteolysis GO:0030162 21 21 0,000 0,15792034 0,18644919 ! chemotaxis GO:0006935 90 89 1,000 0,16327846 0,19265186 GO:0042330|taxis, ! cellular di-, tri-valent inorganic cation homeostasis GO:0030005 89 89 1,000 0,16327846 0,1925286 ! RNA export from nucleus GO:0006405 22 22 0,000 0,16479546 0,19419312 ! cellular amide metabolic process GO:0043603 22 22 0,000 0,16479546 0,19406903 ! regulation of ion transport GO:0043269 22 22 0,000 0,16479546 0,19394511 ! odontogenesis GO:0042476 22 22 0,000 0,16479546 0,19382134 ! hormone-mediated signaling GO:0009755 22 22 0,000 0,16479546 0,19369773 ! ovulation cycle process GO:0022602 22 22 0,000 0,16479546 0,19357427 ! pigment biosynthetic process GO:0046148 22 22 0,000 0,16479546 0,19345098 ! respiratory gaseous exchange GO:0007585 22 22 0,000 0,16479546 0,19332784 ! male sex differentiation GO:0046661 22 22 0,000 0,16479546 0,19320486 ! sterol biosynthetic process GO:0016126 22 22 0,000 0,16479546 0,19308203 ! biopolymer methylation GO:0043414 22 22 0,000 0,16479546 0,19295936 GO:0032259|methylation, ! detection of external stimulus GO:0009581 23 22 0,000 0,16479546 0,19283685 ! neuron migration GO:0001764 22 22 0,000 0,16479546 0,19271449 ! regulation of Wnt receptor signaling pathway GO:0030111 23 22 0,000 0,16479546 0,19259229 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 22 22 0,000 0,16479546 0,19247024 ! fatty acid catabolic process GO:0009062 23 22 0,000 0,16479546 0,19234835 ! aerobic respiration GO:0009060 22 22 0,000 0,16479546 0,19222661 ! cytokine production GO:0001816 22 22 0,000 0,16479546 0,19210502 ! pyrimidine nucleotide metabolic process GO:0006220 22 22 0,000 0,16479546 0,19198359 ! brain development GO:0007420 91 90 1,000 0,16616024 0,19345124 ! di-, tri-valent inorganic cation homeostasis GO:0055066 91 91 1,000 0,16905122 0,1966928 ! response to hydrogen peroxide GO:0042542 24 23 0,000 0,17161545 0,19955033 ! regulation of hormone secretion GO:0046883 23 23 0,000 0,17161545 0,19942451 ! response to estrogen stimulus GO:0043627 23 23 0,000 0,17161545 0,19929885 ! negative regulation of protein complex disassembly GO:0043242 23 23 0,000 0,17161545 0,19917334 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 23 23 0,000 0,17161545 0,199048 ! induction of apoptosis by extracellular signals GO:0008624 23 23 0,000 0,17161545 0,19892281 ! regulation of ARF protein signal transduction GO:0032012 23 23 0,000 0,17161545 0,19879778 ! lipoprotein biosynthetic process GO:0042158 23 23 0,000 0,17161545 0,19867291 ! female gonad development GO:0008585 23 23 0,000 0,17161545 0,19854819 ! monovalent inorganic cation homeostasis GO:0055067 23 23 0,000 0,17161545 0,19842363 ! lipid homeostasis GO:0055088 23 23 0,000 0,17161545 0,19829923 ! Rho protein signal transduction GO:0007266 24 23 0,000 0,17161545 0,19817498 ! regulation of JNK cascade GO:0046328 25 23 0,000 0,17161545 0,19805089 ! energy derivation by oxidation of organic compounds GO:0015980 94 92 1,000 0,17195107 0,19831403 ! regulation of response to stress GO:0080134 97 94 1,000 0,17777608 0,20490389 ! cofactor metabolic process GO:0051186 95 94 1,000 0,17777608 0,20477582 ! mitochondrial transport GO:0006839 24 24 0,000 0,17838073 0,20534396 ! cellular amino acid biosynthetic process GO:0008652 24 24 0,000 0,17838073 0,20521578 ! heterocycle biosynthetic process GO:0018130 24 24 0,000 0,17838073 0,20508776 ! nucleotide catabolic process GO:0009166 24 24 0,000 0,17838073 0,2049599 ! ovulation cycle GO:0042698 24 24 0,000 0,17838073 0,2048322 ! fertilization GO:0009566 25 24 0,000 0,17838073 0,20470466 ! oxidoreduction coenzyme metabolic process GO:0006733 24 24 0,000 0,17838073 0,20457728 ! epithelial tube morphogenesis GO:0060562 25 24 0,000 0,17838073 0,20445005 ! glucan metabolic process GO:0044042 25 24 0,000 0,17838073 0,20432298 GO:0006073|cellular glucan metabolic process, GO:0005977|glycogen metabolic process, ! regulation of actin filament polymerization GO:0030833 25 25 0,000 0,18509174 0,21187831 ! negative regulation of secretion GO:0051048 26 25 0,000 0,18509174 0,21174679 ! protein amino acid N-linked glycosylation GO:0006487 25 25 0,000 0,18509174 0,21161543 ! sensory perception of chemical stimulus GO:0007606 25 25 0,000 0,18509174 0,21148424 ! alcohol biosynthetic process GO:0046165 25 25 0,000 0,18509174 0,2113532 ! development of primary female sexual characteristics GO:0046545 25 25 0,000 0,18509174 0,21122234 GO:0046660|female sex differentiation, ! polysaccharide biosynthetic process GO:0000271 25 25 0,000 0,18509174 0,21109163 ! excretion GO:0007588 25 25 0,000 0,18509174 0,21096108 ! gastrulation GO:0007369 25 25 0,000 0,18509174 0,2108307 ! icosanoid metabolic process GO:0006690 25 25 0,000 0,18509174 0,21070048 ! regulation of endocytosis GO:0030100 25 25 0,000 0,18509174 0,21057041 ! JAK-STAT cascade GO:0007259 26 25 0,000 0,18509174 0,21044051 ! positive regulation of cytokine production GO:0001819 25 25 0,000 0,18509174 0,21031077 ! regulation of system process GO:0044057 98 98 1,000 0,18951846 0,21520796 ! positive regulation of defense response GO:0031349 26 26 0,000 0,1917489 0,21760667 ! transforming growth factor beta receptor signaling pathway GO:0007179 26 26 0,000 0,1917489 0,21747275 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 26 26 0,000 0,1917489 0,21733901 ! negative regulation of cell migration GO:0030336 26 26 0,000 0,1917489 0,21720542 ! induction of apoptosis by intracellular signals GO:0008629 26 26 0,000 0,1917489 0,21707201 ! cellular defense response GO:0006968 26 26 0,000 0,1917489 0,21693875 ! positive regulation of cytokine biosynthetic process GO:0042108 26 26 0,000 0,1917489 0,21680566 ! double-strand break repair GO:0006302 27 26 0,000 0,1917489 0,21667273 ! regulation of protein secretion GO:0050708 26 26 0,000 0,1917489 0,21653997 ! germ cell development GO:0007281 27 26 0,000 0,1917489 0,21640736 ! regulation of blood vessel size GO:0050880 27 26 0,000 0,1917489 0,21627492 GO:0035150|regulation of tube size, ! pigment metabolic process GO:0042440 26 26 0,000 0,1917489 0,21614265 ! anti-apoptosis GO:0006916 100 99 1,000 0,1924715 0,21682455 ! chloride transport GO:0006821 27 27 0,000 0,19835265 0,22331333 ! learning or memory GO:0007611 28 27 0,000 0,19835265 0,223177 ! monocarboxylic acid transport GO:0015718 27 27 0,000 0,19835265 0,22304083 ! activation of caspase activity GO:0006919 27 27 0,000 0,19835265 0,22290483 ! defense response to bacterium GO:0042742 27 27 0,000 0,19835265 0,222769 ! isoprenoid metabolic process GO:0006720 27 27 0,000 0,19835265 0,22263333 ! glutamine family amino acid metabolic process GO:0009064 28 27 0,000 0,19835265 0,22249783 ! tRNA aminoacylation for protein translation GO:0006418 28 28 0,000 0,20490339 0,22970617 GO:0043038|amino acid activation, GO:0043039|tRNA aminoacylation, ! stress-activated protein kinase signaling pathway GO:0031098 28 28 0,000 0,20490339 0,22956653 GO:0007254|JNK cascade, ! neuromuscular process GO:0050905 28 28 0,000 0,20490339 0,22942706 ! regulation of muscle contraction GO:0006937 28 28 0,000 0,20490339 0,22928776 ! unsaturated fatty acid metabolic process GO:0033559 28 28 0,000 0,20490339 0,22914863 ! sulfur compound biosynthetic process GO:0044272 28 28 0,000 0,20490339 0,22900967 ! keratinocyte differentiation GO:0030216 28 28 0,000 0,20490339 0,22887088 ! developmental growth GO:0048589 28 28 0,000 0,20490339 0,22873225 ! glycerophospholipid biosynthetic process GO:0046474 30 29 0,000 0,21140155 0,23584326 ! phosphoinositide metabolic process GO:0030384 29 29 0,000 0,21140155 0,23570058 ! antigen processing and presentation GO:0019882 29 29 0,000 0,21140155 0,23555808 ! tRNA processing GO:0008033 29 29 0,000 0,21140155 0,23541575 ! adult behavior GO:0030534 30 29 0,000 0,21140155 0,23527359 ! regulation of protein polymerization GO:0032271 29 29 0,000 0,21140155 0,2351316 ! transition metal ion transport GO:0000041 31 30 0,000 0,21784755 0,24215502 ! RNA catabolic process GO:0006401 30 30 0,000 0,21784755 0,24200906 ! response to reactive oxygen species GO:0000302 31 30 0,000 0,21784755 0,24186327 ! ER to Golgi vesicle-mediated transport GO:0006888 30 30 0,000 0,21784755 0,24171766 ! positive regulation of peptidase activity GO:0010952 30 30 0,000 0,21784755 0,24157222 GO:0043280|positive regulation of caspase activity, ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 30 30 0,000 0,21784755 0,24142696 ! neuropeptide signaling pathway GO:0007218 30 30 0,000 0,21784755 0,24128187 ! regulation of protein complex disassembly GO:0043244 30 30 0,000 0,21784755 0,24113696 ! positive regulation of protein amino acid phosphorylation GO:0001934 30 30 0,000 0,21784755 0,24099222 ! response to temperature stimulus GO:0009266 30 30 0,000 0,21784755 0,24084765 ! immunoglobulin mediated immune response GO:0016064 30 30 0,000 0,21784755 0,24070326 GO:0019724|B cell mediated immunity, ! regulation of inflammatory response GO:0050727 30 30 0,000 0,21784755 0,24055904 ! water-soluble vitamin metabolic process GO:0006767 30 30 0,000 0,21784755 0,24041499 ! vesicle organization GO:0016050 30 30 0,000 0,21784755 0,24027111 ! regulation of translational initiation GO:0006446 31 31 0,000 0,22424179 0,24717561 ! membrane fusion GO:0006944 31 31 0,000 0,22424179 0,24702786 ! B cell activation GO:0042113 31 31 0,000 0,22424179 0,2468803 ! negative regulation of cytoskeleton organization GO:0051494 32 31 0,000 0,22424179 0,2467329 ! lipoprotein metabolic process GO:0042157 31 31 0,000 0,22424179 0,24658569 ! ion transmembrane transport GO:0034220 31 31 0,000 0,22424179 0,24643865 GO:0015985|energy coupled proton transport, down electrochemical gradient, GO:0015986|ATP synthesis coupled proton transport, ! aging GO:0007568 32 31 0,000 0,22424179 0,24629178 ! glycerolipid biosynthetic process GO:0045017 32 31 0,000 0,22424179 0,24614509 ! digestion GO:0007586 31 31 0,000 0,22424179 0,24599858 ! nucleoside metabolic process GO:0009116 31 31 0,000 0,22424179 0,24585224 ! sphingolipid metabolic process GO:0006665 31 31 0,000 0,22424179 0,24570607 ! camera-type eye development GO:0043010 31 31 0,000 0,22424179 0,24556008 ! ribonucleoprotein complex assembly GO:0022618 32 31 0,000 0,22424179 0,24541426 ! epidermal cell differentiation GO:0009913 31 31 0,000 0,22424179 0,24526861 ! negative regulation of cell motion GO:0051271 31 31 0,000 0,22424179 0,24512314 ! cell redox homeostasis GO:0045454 32 32 0,000 0,23058468 0,25190727 ! lipid modification GO:0030258 32 32 0,000 0,23058468 0,25175803 ! glycosaminoglycan metabolic process GO:0030203 34 32 0,000 0,23058468 0,25160898 ! regulation of vesicle-mediated transport GO:0060627 33 32 0,000 0,23058468 0,2514601 ! nuclear export GO:0051168 32 32 0,000 0,23058468 0,25131139 ! kidney development GO:0001822 32 32 0,000 0,23058468 0,25116286 ! protein maturation by peptide bond cleavage GO:0051605 32 32 0,000 0,23058468 0,25101451 ! amino acid transport GO:0006865 33 33 0,000 0,23687663 0,2577117 ! regulation of protein complex assembly GO:0043254 33 33 0,000 0,23687663 0,25755966 ! membrane lipid metabolic process GO:0006643 33 33 0,000 0,23687663 0,2574078 ! regulation of actin polymerization or depolymerization GO:0008064 33 33 0,000 0,23687663 0,25725611 ! regulation of neuron differentiation GO:0045664 34 33 0,000 0,23687663 0,25710461 ! regulation of synaptic transmission GO:0050804 33 33 0,000 0,23687663 0,25695328 ! regulation of actin filament length GO:0030832 34 34 0,000 0,24311803 0,26356855 ! response to metal ion GO:0010038 34 34 0,000 0,24311803 0,2634136 ! cellular polysaccharide metabolic process GO:0044264 35 34 0,000 0,24311803 0,26325883 ! coenzyme biosynthetic process GO:0009108 34 34 0,000 0,24311803 0,26310425 ! nucleoside monophosphate biosynthetic process GO:0009124 34 34 0,000 0,24311803 0,26294984 ! secondary metabolic process GO:0019748 34 34 0,000 0,24311803 0,26279562 ! detection of stimulus GO:0051606 36 34 0,000 0,24311803 0,26264158 ! acute inflammatory response GO:0002526 35 35 0,000 0,2493093 0,26917225 ! regulation of cellular component size GO:0032535 35 35 0,000 0,2493093 0,26901466 ! regulation of cytokine biosynthetic process GO:0042035 35 35 0,000 0,2493093 0,26885725 ! mesoderm development GO:0007498 35 35 0,000 0,2493093 0,26870002 ! multicellular organism reproduction GO:0032504 36 35 0,000 0,2493093 0,26854298 GO:0048609|reproductive process in a multicellular organism, ! inorganic anion transport GO:0015698 35 35 0,000 0,2493093 0,26838612 ! response to steroid hormone stimulus GO:0048545 35 35 0,000 0,2493093 0,26822944 ! hydrogen transport GO:0006818 36 36 0,000 0,25545081 0,27467669 GO:0015992|proton transport, ! response to inorganic substance GO:0010035 36 36 0,000 0,25545081 0,27451653 ! aminoglycan metabolic process GO:0006022 38 36 0,000 0,25545081 0,27435655 ! oxygen and reactive oxygen species metabolic process GO:0006800 37 36 0,000 0,25545081 0,27419677 ! embryonic limb morphogenesis GO:0030326 36 36 0,000 0,25545081 0,27403716 GO:0035113|embryonic appendage morphogenesis, ! female pregnancy GO:0007565 37 36 0,000 0,25545081 0,27387775 ! RNA elongation from RNA polymerase II promoter GO:0006368 36 36 0,000 0,25545081 0,27371852 ! heterocycle catabolic process GO:0046700 36 36 0,000 0,25545081 0,27355947 ! regulation of transmission of nerve impulse GO:0051969 36 36 0,000 0,25545081 0,27340061 ! gonad development GO:0008406 36 36 0,000 0,25545081 0,27324193 ! coagulation GO:0050817 39 36 0,000 0,25545081 0,27308344 GO:0007596|blood coagulation, ! response to drug GO:0042493 37 37 0,000 0,26154297 0,27943403 ! lymphocyte mediated immunity GO:0002449 37 37 0,000 0,26154297 0,27927213 ! ATP synthesis coupled electron transport GO:0042773 37 37 0,000 0,26154297 0,27911042 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! cellular amino acid catabolic process GO:0009063 38 37 0,000 0,26154297 0,2789489 ! regulation of Rho protein signal transduction GO:0035023 37 37 0,000 0,26154297 0,27878757 ! positive regulation of secretion GO:0051047 39 38 0,000 0,26758617 0,28506434 ! cellular hormone metabolic process GO:0034754 39 38 0,000 0,26758617 0,28489966 ! RNA elongation GO:0006354 38 38 0,000 0,26758617 0,28473517 ! regulation of neurological system process GO:0031644 38 38 0,000 0,26758617 0,28457087 ! hemostasis GO:0007599 42 39 0,000 0,27358079 0,2907782 ! positive regulation of protein modification process GO:0031401 39 39 0,000 0,27358079 0,2906106 ! response to unfolded protein GO:0006986 39 39 0,000 0,27358079 0,2904432 ! nucleoside monophosphate metabolic process GO:0009123 39 39 0,000 0,27358079 0,29027599 ! fatty acid biosynthetic process GO:0006633 39 39 0,000 0,27358079 0,29010897 ! intracellular protein transmembrane transport GO:0065002 39 39 0,000 0,27358079 0,28994215 ! limb development GO:0060173 39 39 0,000 0,27358079 0,28977551 GO:0048736|appendage development, GO:0035107|appendage morphogenesis, ! DNA catabolic process GO:0006308 41 40 0,000 0,27952721 0,29590388 ! amine catabolic process GO:0009310 42 41 0,000 0,28542582 0,30197462 ! regulation of caspase activity GO:0043281 41 41 0,000 0,28542582 0,30180137 ! phospholipid biosynthetic process GO:0008654 42 41 0,000 0,28542582 0,30162832 ! leukocyte mediated immunity GO:0002443 41 41 0,000 0,28542582 0,30145546 ! regulation of Ras GTPase activity GO:0032318 41 41 0,000 0,28542582 0,30128281 ! respiratory electron transport chain GO:0022904 43 42 0,000 0,29127699 0,30728305 ! regulation of endopeptidase activity GO:0052548 42 42 0,000 0,29127699 0,30710726 ! development of primary sexual characteristics GO:0045137 42 42 0,000 0,29127699 0,30693167 ! protein ubiquitination GO:0016567 43 42 0,000 0,29127699 0,30675628 ! negative regulation of ligase activity GO:0051352 43 42 0,000 0,29127699 0,30658109 GO:0051444|negative regulation of ubiquitin-protein ligase activity, GO:0051436|negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle, ! response to protein stimulus GO:0051789 42 42 0,000 0,29127699 0,3064061 ! forebrain development GO:0030900 43 42 0,000 0,29127699 0,30623131 ! one-carbon metabolic process GO:0006730 42 42 0,000 0,29127699 0,30605672 ! mitochondrion organization GO:0007005 44 43 0,000 0,2970811 0,31197747 ! humoral immune response GO:0006959 44 44 0,000 0,30283851 0,31784247 ! mRNA transport GO:0051028 44 44 0,000 0,30283851 0,31766157 ! vitamin metabolic process GO:0006766 44 44 0,000 0,30283851 0,31748088 ! regulation of actin cytoskeleton organization GO:0032956 46 45 0,000 0,30854961 0,32328421 ! steroid biosynthetic process GO:0006694 46 45 0,000 0,30854961 0,32310053 ! Wnt receptor signaling pathway GO:0016055 46 45 0,000 0,30854961 0,32291705 ! protein processing GO:0016485 45 45 0,000 0,30854961 0,32273378 ! regulation of actin filament-based process GO:0032970 47 46 0,000 0,31421475 0,32847293 ! regulation of peptidase activity GO:0052547 46 46 0,000 0,31421475 0,32828672 ! transcription initiation from RNA polymerase II promoter GO:0006367 46 46 0,000 0,31421475 0,32810072 ! regulation of blood pressure GO:0008217 48 47 0,000 0,31983429 0,3337795 ! amine transport GO:0015837 47 47 0,000 0,31983429 0,33359061 ! rhythmic process GO:0048511 47 47 0,000 0,31983429 0,33340192 ! glycerophospholipid metabolic process GO:0006650 49 48 0,000 0,3254086 0,33902095 ! cellular lipid catabolic process GO:0044242 50 49 0,000 0,33093804 0,3445869 ! response to bacterium GO:0009617 50 49 0,000 0,33093804 0,34439233 ! cofactor biosynthetic process GO:0051188 49 49 0,000 0,33093804 0,34419798 ! regulation of defense response GO:0031347 50 50 0,000 0,33642296 0,34970531 ! chromatin assembly GO:0031497 50 50 0,000 0,33642296 0,34950818 GO:0006334|nucleosome assembly, ! RNA transport GO:0050658 50 50 0,000 0,33642296 0,34931128 GO:0050657|nucleic acid transport, GO:0051236|establishment of RNA localization, ! nitrogen compound catabolic process GO:0044270 51 50 0,000 0,33642296 0,34911459 ! regulation of neurogenesis GO:0050767 51 50 0,000 0,33642296 0,34891813 ! transcription initiation GO:0006352 50 50 0,000 0,33642296 0,34872189 ! rRNA metabolic process GO:0016072 51 51 0,000 0,34186371 0,35416235 GO:0006364|rRNA processing, ! protein-DNA complex assembly GO:0065004 51 51 0,000 0,34186371 0,35396338 ! ATP biosynthetic process GO:0006754 51 51 0,000 0,34186371 0,35376463 ! protein maturation GO:0051604 51 51 0,000 0,34186371 0,35356611 ! RNA localization GO:0006403 52 52 0,000 0,34726064 0,35894636 ! cell fate commitment GO:0045165 52 52 0,000 0,34726064 0,35874515 ! regulation of GTPase activity GO:0043087 53 52 0,000 0,34726064 0,35854418 ! regulation of body fluid levels GO:0050878 55 52 0,000 0,34726064 0,35834342 ! sodium ion transport GO:0006814 53 53 0,000 0,35261409 0,36366412 ! tRNA metabolic process GO:0006399 53 53 0,000 0,35261409 0,36346073 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 53 53 0,000 0,35261409 0,36325756 ! carbohydrate biosynthetic process GO:0016051 53 53 0,000 0,35261409 0,36305462 ! nucleosome organization GO:0034728 55 55 0,000 0,36319196 0,3737369 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 55 55 0,000 0,36319196 0,37352834 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! in utero embryonic development GO:0001701 55 55 0,000 0,36319196 0,37332002 ! ribonucleoside triphosphate biosynthetic process GO:0009201 56 56 0,000 0,36841706 0,37847973 ! regulation of nervous system development GO:0051960 57 56 0,000 0,36841706 0,37826888 ! ATP metabolic process GO:0046034 57 57 0,000 0,37360003 0,38337687 ! nucleoside triphosphate biosynthetic process GO:0009142 57 57 0,000 0,37360003 0,38316353 ! innate immune response GO:0045087 58 58 0,000 0,37874123 0,3882203 ! carboxylic acid transport GO:0046942 59 59 0,000 0,38384098 0,39322898 GO:0015849|organic acid transport, ! potassium ion transport GO:0006813 60 60 0,000 0,38889961 0,39818999 ! cellular respiration GO:0045333 62 61 0,000 0,39391744 0,40310375 ! carboxylic acid catabolic process GO:0046395 63 61 0,000 0,39391744 0,40288005 GO:0016054|organic acid catabolic process, ! positive regulation of cellular protein metabolic process GO:0032270 61 61 0,000 0,39391744 0,4026566 ! lipid transport GO:0006869 62 62 0,000 0,3988948 0,40751836 ! purine ribonucleoside triphosphate metabolic process GO:0009205 62 62 0,000 0,3988948 0,40729259 ! regulation of cellular component biogenesis GO:0044087 63 62 0,000 0,3988948 0,40706707 ! regulation of secretion GO:0051046 65 63 0,000 0,40383201 0,41187737 ! ribonucleoside triphosphate metabolic process GO:0009199 63 63 0,000 0,40383201 0,41164956 ! purine nucleoside triphosphate metabolic process GO:0009144 63 63 0,000 0,40383201 0,411422 ! glycerolipid metabolic process GO:0046486 65 64 0,000 0,40872939 0,41618136 ! regulation of cytoskeleton organization GO:0051493 66 64 0,000 0,40872939 0,41595155 ! positive regulation of protein metabolic process GO:0051247 64 64 0,000 0,40872939 0,415722 ! anion transport GO:0006820 65 65 0,000 0,41358725 0,42043094 ! protein amino acid glycosylation GO:0006486 66 66 0,000 0,4184059 0,42509486 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! nucleoside triphosphate metabolic process GO:0009141 66 66 0,000 0,4184059 0,42486064 ! DNA packaging GO:0006323 66 66 0,000 0,4184059 0,42462669 ! polysaccharide metabolic process GO:0005976 69 66 0,000 0,4184059 0,42439299 ! muscle contraction GO:0006936 67 67 0,000 0,42318566 0,42900504 ! negative regulation of cell differentiation GO:0045596 68 67 0,000 0,42318566 0,42876919 ! Ras protein signal transduction GO:0007265 69 67 0,000 0,42318566 0,42853361 ! purine ribonucleotide biosynthetic process GO:0009152 68 68 0,000 0,42792683 0,43309673 ! chromatin assembly or disassembly GO:0006333 68 68 0,000 0,42792683 0,43285902 ! regulation of translation GO:0006417 69 69 0,000 0,43262972 0,43737607 ! sensory perception of sound GO:0007605 71 69 0,000 0,43262972 0,43713628 GO:0050954|sensory perception of mechanical stimulus, ! carboxylic acid biosynthetic process GO:0046394 70 70 0,000 0,43729463 0,44160768 GO:0016053|organic acid biosynthetic process, ! oxidative phosphorylation GO:0006119 71 71 0,000 0,44192187 0,44603615 ! ribosome biogenesis GO:0042254 71 71 0,000 0,44192187 0,44579202 ! muscle system process GO:0003012 72 72 0,000 0,44651174 0,45017567 ! electron transport chain GO:0022900 75 74 0,000 0,45558051 0,45906774 ! ribonucleotide biosynthetic process GO:0009260 75 75 0,000 0,46006002 0,4633282 ! purine ribonucleotide metabolic process GO:0009150 75 75 0,000 0,46006002 0,46307516 ! glycoprotein biosynthetic process GO:0009101 80 80 0,000 0,48192017 0,4848138 ! lipid catabolic process GO:0016042 82 81 0,000 0,48618671 0,48883912 ! ribonucleotide metabolic process GO:0009259 83 83 0,000 0,49461652 0,49704376 ! ncRNA processing GO:0034470 83 83 0,000 0,49461652 0,49677289 ! organophosphate metabolic process GO:0019637 87 86 0,000 0,50700715 0,50894019 GO:0006644|phospholipid metabolic process, ! male gamete generation GO:0048232 90 88 0,000 0,51510131 0,51678373 GO:0007283|spermatogenesis, ! purine nucleotide biosynthetic process GO:0006164 88 88 0,000 0,51510131 0,51650256 ! regulation of Ras protein signal transduction GO:0046578 90 90 0,000 0,5230649 0,52420262 ! visual perception GO:0007601 93 92 0,000 0,5309 0,5317656 GO:0050953|sensory perception of light stimulus, ! fatty acid metabolic process GO:0006631 93 92 0,000 0,5309 0,53147676 ! endocytosis GO:0006897 99 98 0,000 0,55365458 0,55395515 GO:0010324|membrane invagination, ! glycoprotein metabolic process GO:0009100 99 98 0,000 0,55365458 0,55365458