pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6789-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! G1/S transition of mitotic cell cycle GO:0000082 124 46 7,000 2,135E-10 5,216E-07 ! interphase of mitotic cell cycle GO:0051329 224 98 9,000 2,675E-10 3,267E-07 ! positive regulation of cell cycle GO:0045787 96 48 7,000 3,058E-10 2,49E-07 ! lung development GO:0030324 165 69 7,000 6,115E-09 3,735E-06 ! respiratory tube development GO:0030323 171 72 7,000 8,627E-09 4,215E-06 ! respiratory system development GO:0060541 175 74 7,000 1,076E-08 4,38E-06 ! auditory receptor cell differentiation GO:0042491 36 17 4,000 3,385E-08 1,181E-05 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 6,000 3,709E-08 1,133E-05 ! apoptotic mitochondrial changes GO:0008637 42 20 4,000 8,363E-08 2,27E-05 ! ear development GO:0043583 114 66 6,000 1,046E-07 2,556E-05 ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 4,000 1,407E-07 3,126E-05 ! inner ear receptor cell differentiation GO:0060113 42 22 4,000 1,407E-07 2,865E-05 ! negative regulation of protein kinase activity GO:0006469 144 69 6,000 1,429E-07 2,685E-05 ! negative regulation of kinase activity GO:0033673 145 70 6,000 1,58E-07 2,756E-05 ! mechanoreceptor differentiation GO:0042490 48 24 4,000 2,251E-07 3,665E-05 ! negative regulation of phosphorylation GO:0042326 52 24 4,000 2,251E-07 3,436E-05 ! negative regulation of transferase activity GO:0051348 155 74 6,000 2,326E-07 3,343E-05 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 4,000 3,451E-07 4,683E-05 GO:0045936|negative regulation of phosphate metabolic process, ! insulin receptor signaling pathway GO:0008286 66 27 4,000 4,215E-07 5,42E-05 ! regulation of B cell proliferation GO:0030888 22 12 3,000 4,933E-07 6,025E-05 ! inner ear development GO:0048839 89 53 5,000 5,916E-07 6,883E-05 ! stem cell division GO:0017145 11 5 2,000 1,82E-06 2,021E-04 GO:0048103|somatic stem cell division, ! cellular response to insulin stimulus GO:0032869 85 38 4,000 2,491E-06 2,645E-04 ! negative regulation of cell size GO:0045792 144 69 5,000 2,864E-06 2,915E-04 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 3,000 2,968E-06 2,901E-04 ! cell cycle checkpoint GO:0000075 145 71 5,000 3,389E-06 3,184E-04 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 3,000 5,729E-06 5,183E-04 ! prostate gland development GO:0030850 14 7 2,000 6,317E-06 5,512E-04 ! response to insulin stimulus GO:0032868 98 47 4,000 7,3E-06 6,15E-04 ! regulation of mast cell proliferation GO:0070666 89 49 4,000 8,991E-06 7,322E-04 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 2,000 1,006E-05 7,931E-04 ! regulation of T cell differentiation in the thymus GO:0033081 14 8 2,000 1,006E-05 7,684E-04 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 2,000 1,006E-05 7,451E-04 ! negative regulation of immune system process GO:0002683 101 51 4,000 1,097E-05 7,885E-04 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 3,000 1,189E-05 8,301E-04 ! regulation of leukocyte proliferation GO:0070663 97 53 4,000 1,328E-05 9,014E-04 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 2,000 1,503E-05 9,926E-04 ! response to UV GO:0009411 120 55 4,000 1,595E-05 1,026E-03 ! positive regulation of MAP kinase activity GO:0043406 174 93 5,000 1,625E-05 1,018E-03 ! positive regulation of cell migration GO:0030335 137 58 4,000 2,072E-05 1,266E-03 ! regulation of developmental growth GO:0048638 16 10 2,000 2,139E-05 1,274E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 2,000 2,139E-05 1,244E-03 ! positive regulation of B cell proliferation GO:0030890 18 10 2,000 2,139E-05 1,215E-03 ! protein sumoylation GO:0016925 17 10 2,000 2,139E-05 1,187E-03 ! regulation of B cell activation GO:0050864 55 30 3,000 2,52E-05 1,368E-03 ! cellular response to extracellular stimulus GO:0031668 52 31 3,000 2,88E-05 1,529E-03 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 2,000 2,928E-05 1,522E-03 ! regulation of embryonic development GO:0045995 35 11 2,000 2,928E-05 1,49E-03 ! protein amino acid autophosphorylation GO:0046777 157 64 4,000 3,354E-05 1,672E-03 ! response to peptide hormone stimulus GO:0043434 129 64 4,000 3,354E-05 1,639E-03 ! positive regulation of cell motion GO:0051272 157 65 4,000 3,617E-05 1,733E-03 ! positive regulation of cellular catabolic process GO:0031331 34 12 2,000 3,888E-05 1,826E-03 ! negative regulation of mast cell proliferation GO:0070667 24 12 2,000 3,888E-05 1,792E-03 GO:0042130|negative regulation of T cell proliferation, ! negative regulation of cell growth GO:0030308 142 67 4,000 4,19E-05 1,896E-03 ! DNA damage checkpoint GO:0000077 78 35 3,000 4,707E-05 2,091E-03 ! regulation of monooxygenase activity GO:0032768 35 13 2,000 5,033E-05 2,196E-03 ! androgen receptor signaling pathway GO:0030521 81 37 3,000 5,885E-05 2,522E-03 ! regulation of MAPKKK cascade GO:0043408 157 72 4,000 5,932E-05 2,498E-03 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 2,000 6,378E-05 2,641E-03 ! meiosis I GO:0007127 74 38 3,000 6,548E-05 2,666E-03 ! DNA integrity checkpoint GO:0031570 82 38 3,000 6,548E-05 2,622E-03 ! actin cytoskeleton reorganization GO:0031532 38 15 2,000 7,939E-05 3,128E-03 ! negative regulation of immune response GO:0050777 38 16 2,000 9,73E-05 3,773E-03 ! negative regulation of leukocyte proliferation GO:0070664 32 16 2,000 9,73E-05 3,714E-03 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! regulation of T cell differentiation GO:0045580 78 42 3,000 9,754E-05 3,666E-03 ! regulation of T cell proliferation GO:0042129 80 43 3,000 1,071E-04 3,963E-03 ! energy reserve metabolic process GO:0006112 76 44 3,000 1,172E-04 4,275E-03 ! regulation of survival gene product expression GO:0045884 38 17 2,000 1,177E-04 4,227E-03 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 2,000 1,177E-04 4,166E-03 ! regulation of epithelial cell proliferation GO:0050678 122 45 3,000 1,281E-04 4,471E-03 ! negative regulation of growth GO:0045926 168 85 4,000 1,31E-04 4,506E-03 ! cellular response to hormone stimulus GO:0032870 182 85 4,000 1,31E-04 4,444E-03 ! mitochondrion organization GO:0007005 159 87 4,000 1,462E-04 4,892E-03 ! regulation of DNA binding GO:0051101 167 89 4,000 1,627E-04 5,371E-03 ! cellular component disassembly GO:0022411 89 48 3,000 1,651E-04 5,377E-03 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 3,000 1,651E-04 5,306E-03 ! regulation of cell cycle process GO:0010564 161 90 4,000 1,715E-04 5,44E-03 ! regulation of lymphocyte differentiation GO:0045619 92 49 3,000 1,79E-04 5,605E-03 ! gland development GO:0048732 220 91 4,000 1,806E-04 5,585E-03 ! regulation of cell adhesion GO:0030155 241 92 4,000 1,901E-04 5,806E-03 ! peptidyl-serine phosphorylation GO:0018105 44 20 2,000 1,948E-04 5,874E-03 ! negative regulation of T cell activation GO:0050868 41 20 2,000 1,948E-04 5,803E-03 ! cell structure disassembly during apoptosis GO:0006921 32 21 2,000 2,263E-04 6,66E-03 ! positive regulation of growth GO:0045927 96 53 3,000 2,43E-04 7,066E-03 ! regulation of DNA metabolic process GO:0051052 188 97 4,000 2,435E-04 6,998E-03 ! reciprocal meiotic recombination GO:0007131 44 22 2,000 2,609E-04 7,412E-03 ! cellular response to starvation GO:0009267 37 22 2,000 2,609E-04 7,326E-03 ! apoptotic nuclear changes GO:0030262 34 22 2,000 2,609E-04 7,243E-03 ! peptidyl-serine modification GO:0018209 50 22 2,000 2,609E-04 7,162E-03 ! positive regulation of B cell activation GO:0050871 42 22 2,000 2,609E-04 7,082E-03 ! regulation of DNA recombination GO:0000018 51 23 2,000 2,988E-04 8,021E-03 ! activation of pro-apoptotic gene products GO:0008633 51 23 2,000 2,988E-04 7,934E-03 ! negative regulation of bone resorption GO:0045779 10 5 1,000 3,209E-04 8,43E-03 ! positive regulation of glycolysis GO:0045821 13 5 1,000 3,209E-04 8,341E-03 ! anagen GO:0042640 7 5 1,000 3,209E-04 8,253E-03 ! negative regulation of survival gene product expression GO:0008634 9 5 1,000 3,209E-04 8,167E-03 ! microvillus organization GO:0032528 8 5 1,000 3,209E-04 8,083E-03 GO:0030033|microvillus assembly, ! response to food GO:0032094 6 5 1,000 3,209E-04 8E-03 ! morphogenesis of an epithelial sheet GO:0002011 11 5 1,000 3,209E-04 7,919E-03 ! regulation of phospholipase A2 activity GO:0032429 15 5 1,000 3,209E-04 7,84E-03 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 1,000 3,209E-04 7,763E-03 ! peptidyl-threonine phosphorylation GO:0018107 20 5 1,000 3,209E-04 7,687E-03 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 1,000 3,209E-04 7,612E-03 ! G2/M transition checkpoint GO:0031576 8 5 1,000 3,209E-04 7,539E-03 GO:0031572|G2/M transition DNA damage checkpoint, ! meiotic chromosome segregation GO:0045132 10 5 1,000 3,209E-04 7,467E-03 ! negative regulation of T cell mediated immunity GO:0002710 15 5 1,000 3,209E-04 7,396E-03 GO:0002707|negative regulation of lymphocyte mediated immunity, ! muscle cell proliferation GO:0033002 12 5 1,000 3,209E-04 7,327E-03 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 1,000 3,209E-04 7,26E-03 ! regulation of hair follicle development GO:0051797 10 5 1,000 3,209E-04 7,193E-03 GO:0042634|regulation of hair cycle, ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 1,000 3,209E-04 7,128E-03 ! glial cell migration GO:0008347 10 5 1,000 3,209E-04 7,063E-03 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 1,000 3,209E-04 7E-03 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 1,000 3,209E-04 6,938E-03 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! protein insertion into membrane GO:0051205 17 5 1,000 3,209E-04 6,877E-03 ! positive regulation of cell adhesion GO:0045785 61 24 2,000 3,4E-04 7,223E-03 ! regulation of cellular catabolic process GO:0031329 55 24 2,000 3,4E-04 7,161E-03 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 2,000 3,4E-04 7,1E-03 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 2,000 3,4E-04 7,04E-03 ! regulation of oxidoreductase activity GO:0051341 48 24 2,000 3,4E-04 6,981E-03 ! protein import into nucleus, translocation GO:0000060 51 25 2,000 3,848E-04 7,833E-03 ! molting cycle process GO:0022404 52 26 2,000 4,331E-04 8,745E-03 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! positive regulation of MAPKKK cascade GO:0043410 50 26 2,000 4,331E-04 8,673E-03 ! DNA damage response, signal transduction GO:0042770 136 62 3,000 4,447E-04 8,832E-03 ! regulation of homeostatic process GO:0032844 148 62 3,000 4,447E-04 8,761E-03 ! skeletal system morphogenesis GO:0048705 118 63 3,000 4,727E-04 9,239E-03 ! positive regulation of actin filament polymerization GO:0030838 11 6 1,000 4,796E-04 9,299E-03 ! thymic T cell selection GO:0045061 16 6 1,000 4,796E-04 9,225E-03 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 1,000 4,796E-04 9,153E-03 ! positive regulation of neuroblast proliferation GO:0002052 13 6 1,000 4,796E-04 9,082E-03 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 1,000 4,796E-04 9,012E-03 ! early endosome to late endosome transport GO:0045022 16 6 1,000 4,796E-04 8,944E-03 ! establishment of spindle localization GO:0051293 16 6 1,000 4,796E-04 8,876E-03 GO:0051653|spindle localization, ! negative regulation of gliogenesis GO:0014014 18 6 1,000 4,796E-04 8,809E-03 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 1,000 4,796E-04 8,743E-03 ! enucleate erythrocyte differentiation GO:0043353 14 6 1,000 4,796E-04 8,679E-03 ! hair follicle maturation GO:0048820 8 6 1,000 4,796E-04 8,615E-03 ! salivary gland morphogenesis GO:0007435 14 6 1,000 4,796E-04 8,552E-03 ! negative regulation of B cell activation GO:0050869 14 6 1,000 4,796E-04 8,49E-03 ! response to starvation GO:0042594 47 27 2,000 4,852E-04 8,528E-03 ! regulation of chromosome organization GO:0033044 49 27 2,000 4,852E-04 8,467E-03 ! cellular response to nutrient levels GO:0031669 45 27 2,000 4,852E-04 8,407E-03 ! negative regulation of lymphocyte activation GO:0051250 55 27 2,000 4,852E-04 8,348E-03 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 2,000 5,412E-04 9,246E-03 ! negative regulation of protein modification process GO:0031400 66 28 2,000 5,412E-04 9,181E-03 ! regulation of JUN kinase activity GO:0043506 67 28 2,000 5,412E-04 9,118E-03 ! steroid hormone receptor signaling pathway GO:0030518 146 66 3,000 5,644E-04 9,444E-03 ! activation of MAPK activity GO:0000187 124 67 3,000 5,976E-04 9,931E-03 ! negative regulation of neuron differentiation GO:0045665 46 29 2,000 6,011E-04 9,922E-03 ! regulation of cellular response to stress GO:0080135 142 68 3,000 6,321E-04 0,01036396 ! negative regulation of transcription regulator activity GO:0090048 57 30 2,000 6,651E-04 0,01083216 GO:0043433|negative regulation of transcription factor activity, ! N-terminal protein amino acid acetylation GO:0006474 14 7 1,000 6,689E-04 0,01082176 ! mRNA stabilization GO:0048255 18 7 1,000 6,689E-04 0,01075057 GO:0043489|RNA stabilization, ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 1,000 6,689E-04 0,0106803 ! positive regulation of isotype switching GO:0045830 17 7 1,000 6,689E-04 0,01061095 GO:0045911|positive regulation of DNA recombination, ! male sex determination GO:0030238 15 7 1,000 6,689E-04 0,01054249 ! cranial nerve morphogenesis GO:0021602 12 7 1,000 6,689E-04 0,01047491 ! positive regulation of monooxygenase activity GO:0032770 12 7 1,000 6,689E-04 0,01040819 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 1,000 6,689E-04 0,01034232 GO:0002714|positive regulation of B cell mediated immunity, ! peptidyl-threonine modification GO:0018210 26 7 1,000 6,689E-04 0,01027727 ! dopamine biosynthetic process GO:0042416 18 7 1,000 6,689E-04 0,01021304 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 1,000 6,689E-04 0,0101496 ! cell junction assembly GO:0034329 85 31 2,000 7,333E-04 0,01105787 ! negative regulation of leukocyte activation GO:0002695 60 31 2,000 7,333E-04 0,01099003 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 3,000 7,442E-04 0,01108555 ! spindle organization GO:0007051 50 32 2,000 8,057E-04 0,01192975 ! positive regulation of catabolic process GO:0009896 72 32 2,000 8,057E-04 0,01185788 ! regulation of lipid kinase activity GO:0043550 17 8 1,000 8,885E-04 0,01299752 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 1,000 8,885E-04 0,01292015 ! T-helper 1 type immune response GO:0042088 12 8 1,000 8,885E-04 0,0128437 ! positive regulation of endothelial cell migration GO:0010595 19 8 1,000 8,885E-04 0,01276815 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 1,000 8,885E-04 0,01269348 ! cerebral cortex neuron differentiation GO:0021895 16 8 1,000 8,885E-04 0,01261968 ! regulation of vascular permeability GO:0043114 12 8 1,000 8,885E-04 0,01254674 ! regulation of respiratory burst GO:0060263 12 8 1,000 8,885E-04 0,01247463 ! positive regulation of epidermis development GO:0045684 13 8 1,000 8,885E-04 0,01240335 ! B cell receptor signaling pathway GO:0050853 22 8 1,000 8,885E-04 0,01233287 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 1,000 8,885E-04 0,01226319 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 1,000 8,885E-04 0,0121943 ! regulation of transcription factor activity GO:0051090 137 75 3,000 9,145E-04 0,01248172 GO:0090046|regulation of transcription regulator activity, ! axon guidance GO:0007411 162 75 3,000 9,145E-04 0,01241238 ! cell-matrix adhesion GO:0007160 181 76 3,000 9,611E-04 0,01297192 ! negative regulation of MAP kinase activity GO:0043407 78 34 2,000 9,64E-04 0,01293924 ! regulation of catabolic process GO:0009894 173 77 3,000 1,009E-03 0,0134733 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 3,000 1,111E-03 0,01474638 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 1,138E-03 0,01502843 ! induction of positive chemotaxis GO:0050930 17 9 1,000 1,138E-03 0,01494763 ! regulation of glycolysis GO:0006110 20 9 1,000 1,138E-03 0,0148677 ! middle ear morphogenesis GO:0042474 14 9 1,000 1,138E-03 0,01478862 ! T cell selection GO:0045058 27 9 1,000 1,138E-03 0,01471037 ! receptor clustering GO:0043113 20 9 1,000 1,138E-03 0,01463295 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 1,000 1,138E-03 0,01455633 ! postreplication repair GO:0006301 25 9 1,000 1,138E-03 0,01448052 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 1,000 1,138E-03 0,01440549 GO:0002820|negative regulation of adaptive immune response, ! regulation of macrophage differentiation GO:0045649 16 9 1,000 1,138E-03 0,01433124 ! regulation of synaptogenesis GO:0051963 15 9 1,000 1,138E-03 0,01425774 ! regulation of telomere maintenance GO:0032204 17 9 1,000 1,138E-03 0,014185 ! negative regulation of DNA binding GO:0043392 67 36 2,000 1,141E-03 0,01414418 ! positive regulation of cell development GO:0010720 85 36 2,000 1,141E-03 0,01407274 ! meiosis GO:0007126 143 81 3,000 1,219E-03 0,01496484 GO:0051327|M phase of meiotic cell cycle, ! response to hypoxia GO:0001666 178 81 3,000 1,219E-03 0,01489002 ! cell junction organization GO:0034330 96 37 2,000 1,236E-03 0,01502277 ! tissue remodeling GO:0048771 78 37 2,000 1,236E-03 0,0149484 ! negative regulation of cell activation GO:0050866 69 37 2,000 1,236E-03 0,01487476 ! cell-substrate adhesion GO:0031589 189 82 3,000 1,276E-03 0,01527884 ! protein import into nucleus GO:0006606 174 82 3,000 1,276E-03 0,01520431 ! meiotic cell cycle GO:0051321 144 82 3,000 1,276E-03 0,0151305 ! response to oxygen levels GO:0070482 183 83 3,000 1,335E-03 0,01574989 ! nuclear import GO:0051170 177 83 3,000 1,335E-03 0,01567417 ! positive regulation of DNA metabolic process GO:0051054 77 38 2,000 1,336E-03 0,01562051 ! regulation of protein stability GO:0031647 77 38 2,000 1,336E-03 0,01554612 ! regulation of ligase activity GO:0051340 147 84 3,000 1,395E-03 0,0161522 ! regulation of phosphatase activity GO:0010921 28 10 1,000 1,417E-03 0,01633143 ! SMAD protein nuclear translocation GO:0007184 21 10 1,000 1,417E-03 0,01625476 ! positive regulation of heart contraction GO:0045823 17 10 1,000 1,417E-03 0,0161788 ! lung alveolus development GO:0048286 26 10 1,000 1,417E-03 0,01610355 ! glucan biosynthetic process GO:0009250 14 10 1,000 1,417E-03 0,016029 GO:0005978|glycogen biosynthetic process, ! epithelial cell development GO:0002064 21 10 1,000 1,417E-03 0,01595513 ! motor axon guidance GO:0008045 22 10 1,000 1,417E-03 0,01588194 ! regulation of bone resorption GO:0045124 25 10 1,000 1,417E-03 0,01580942 ! protein heterooligomerization GO:0051291 17 10 1,000 1,417E-03 0,01573756 ! regulation of gliogenesis GO:0014013 23 10 1,000 1,417E-03 0,01566635 GO:0045685|regulation of glial cell differentiation, ! regulation of B cell differentiation GO:0045577 24 10 1,000 1,417E-03 0,01559578 ! salivary gland development GO:0007431 28 10 1,000 1,417E-03 0,01552585 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 1,000 1,417E-03 0,01545653 GO:0043470|regulation of carbohydrate catabolic process, ! negative regulation of immune effector process GO:0002698 23 10 1,000 1,417E-03 0,01538784 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 1,000 1,417E-03 0,01531975 ! negative regulation of binding GO:0051100 71 39 2,000 1,442E-03 0,01551522 ! carbohydrate homeostasis GO:0033500 59 39 2,000 1,442E-03 0,01544717 GO:0042593|glucose homeostasis, ! positive regulation of leukocyte proliferation GO:0070665 70 39 2,000 1,442E-03 0,01537971 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! nucleus organization GO:0006997 73 40 2,000 1,552E-03 0,01648523 ! detection of mechanical stimulus GO:0050982 22 11 1,000 1,726E-03 0,01825004 ! blood vessel remodeling GO:0001974 30 11 1,000 1,726E-03 0,01817138 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 1,000 1,726E-03 0,01809339 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 23 11 1,000 1,726E-03 0,01801606 ! peptide or protein amino-terminal blocking GO:0018409 22 11 1,000 1,726E-03 0,0179394 ! telomere maintenance via telomerase GO:0007004 24 11 1,000 1,726E-03 0,01786339 GO:0010833|telomere maintenance via telomere lengthening, ! positive regulation of T cell mediated immunity GO:0002711 26 11 1,000 1,726E-03 0,01778801 ! neuroblast proliferation GO:0007405 25 11 1,000 1,726E-03 0,01771327 ! regulation of isotype switching GO:0045191 24 11 1,000 1,726E-03 0,01763916 ! apical protein localization GO:0045176 18 11 1,000 1,726E-03 0,01756566 ! positive regulation of leukocyte migration GO:0002687 28 11 1,000 1,726E-03 0,01749278 ! T cell receptor signaling pathway GO:0050852 29 11 1,000 1,726E-03 0,01742049 ! protein localization in nucleus GO:0034504 192 89 3,000 1,727E-03 0,01735926 ! ear morphogenesis GO:0042471 64 42 2,000 1,788E-03 0,01790527 ! dorsal/ventral pattern formation GO:0009953 75 42 2,000 1,788E-03 0,01783219 ! epithelial cell differentiation GO:0030855 83 43 2,000 1,914E-03 0,01901194 ! glucose transport GO:0015758 66 43 2,000 1,914E-03 0,01893497 ! regulation of cell morphogenesis GO:0022604 243 93 3,000 2,029E-03 0,01998333 ! hexose transport GO:0008645 68 44 2,000 2,046E-03 0,02007307 GO:0015749|monosaccharide transport, ! virus-host interaction GO:0019048 30 12 1,000 2,063E-03 0,02015966 ! regulation of positive chemotaxis GO:0050926 22 12 1,000 2,063E-03 0,02007935 GO:0050927|positive regulation of positive chemotaxis, ! protein complex disassembly GO:0043241 28 12 1,000 2,063E-03 0,01999967 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 1,000 2,063E-03 0,01992062 ! hippocampus development GO:0021766 29 12 1,000 2,063E-03 0,01984219 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 1,000 2,063E-03 0,01976438 ! T cell proliferation GO:0042098 32 12 1,000 2,063E-03 0,01968717 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 1,000 2,063E-03 0,01961057 ! focal adhesion formation GO:0048041 37 12 1,000 2,063E-03 0,01953456 ! mitotic spindle organization GO:0007052 23 12 1,000 2,063E-03 0,01945913 ! cranial nerve development GO:0021545 23 12 1,000 2,063E-03 0,01938429 ! histone acetylation GO:0016573 27 12 1,000 2,063E-03 0,01931002 ! autonomic nervous system development GO:0048483 24 12 1,000 2,063E-03 0,01923632 ! peptidyl-lysine modification GO:0018205 21 12 1,000 2,063E-03 0,01916318 ! T cell homeostasis GO:0043029 28 12 1,000 2,063E-03 0,01909059 ! regulation of leukocyte migration GO:0002685 29 12 1,000 2,063E-03 0,01901855 ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 1,000 2,063E-03 0,01894705 ! regulation of synapse organization GO:0050807 18 12 1,000 2,063E-03 0,01887609 ! localization within membrane GO:0051668 26 12 1,000 2,063E-03 0,01880566 ! induction of apoptosis by intracellular signals GO:0008629 95 45 2,000 2,183E-03 0,01982473 ! regulation of T cell activation GO:0050863 175 96 3,000 2,278E-03 0,02060861 ! glycolysis GO:0006096 71 46 2,000 2,325E-03 0,02096348 ! pigmentation GO:0043473 103 46 2,000 2,325E-03 0,02088641 ! cell growth GO:0016049 90 46 2,000 2,325E-03 0,0208099 ! cartilage condensation GO:0001502 22 13 1,000 2,429E-03 0,0216566 ! endocrine pancreas development GO:0031018 25 13 1,000 2,429E-03 0,02157785 ! positive regulation of cell growth GO:0030307 24 13 1,000 2,429E-03 0,02149967 ! regulation of skeletal muscle fiber development GO:0048742 32 13 1,000 2,429E-03 0,02142206 ! exocrine system development GO:0035272 34 13 1,000 2,429E-03 0,021345 ! asymmetric protein localization GO:0008105 24 13 1,000 2,429E-03 0,02126849 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 1,000 2,429E-03 0,02119253 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! gland morphogenesis GO:0022612 31 13 1,000 2,429E-03 0,02111712 ! regulation of epidermis development GO:0045682 19 13 1,000 2,429E-03 0,02104223 ! regulation of mRNA stability GO:0043488 32 13 1,000 2,429E-03 0,02096788 ! cytoplasmic sequestering of protein GO:0051220 25 13 1,000 2,429E-03 0,02089405 ! regulation of synapse structure and activity GO:0050803 19 13 1,000 2,429E-03 0,02082074 ! regulation of JNK cascade GO:0046328 104 47 2,000 2,474E-03 0,02112984 ! positive regulation of DNA binding GO:0043388 83 48 2,000 2,628E-03 0,02236628 ! regulation of S phase GO:0033261 26 14 1,000 2,823E-03 0,02394765 ! hair follicle morphogenesis GO:0031069 27 14 1,000 2,823E-03 0,02386479 ! cell-cell junction assembly GO:0007043 32 14 1,000 2,823E-03 0,0237825 ! RNA-dependent DNA replication GO:0006278 28 14 1,000 2,823E-03 0,02370077 ! T cell differentiation in the thymus GO:0033077 37 14 1,000 2,823E-03 0,0236196 ! catecholamine biosynthetic process GO:0042423 30 14 1,000 2,823E-03 0,02353899 ! regulation of RNA stability GO:0043487 33 14 1,000 2,823E-03 0,02345893 ! release of cytochrome c from mitochondria GO:0001836 31 14 1,000 2,823E-03 0,0233794 ! positive regulation of protein polymerization GO:0032273 27 14 1,000 2,823E-03 0,02330042 ! activation of caspase activity GO:0006919 95 50 2,000 2,953E-03 0,0242885 ! regulation of skeletal muscle tissue development GO:0048641 35 15 1,000 3,245E-03 0,02660453 ! N-terminal protein amino acid modification GO:0031365 30 15 1,000 3,245E-03 0,02651555 ! ER-associated protein catabolic process GO:0030433 24 15 1,000 3,245E-03 0,02642717 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! negative regulation of bone remodeling GO:0046851 34 15 1,000 3,245E-03 0,02633937 ! regulation of T cell mediated immunity GO:0002709 36 15 1,000 3,245E-03 0,02625215 ! positive regulation of oxidoreductase activity GO:0051353 22 15 1,000 3,245E-03 0,02616551 ! dopamine metabolic process GO:0042417 35 15 1,000 3,245E-03 0,02607944 ! lymphocyte homeostasis GO:0002260 33 15 1,000 3,245E-03 0,02599393 ! epithelial to mesenchymal transition GO:0001837 30 15 1,000 3,245E-03 0,02590899 ! positive regulation of binding GO:0051099 88 52 2,000 3,302E-03 0,02627411 ! regulation of angiogenesis GO:0045765 125 54 2,000 3,675E-03 0,02914877 ! regulation of cell shape GO:0008360 142 54 2,000 3,675E-03 0,02905443 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 3,695E-03 0,02911866 ! positive regulation of cell size GO:0045793 29 16 1,000 3,695E-03 0,02902503 ! regulation of dephosphorylation GO:0035303 43 16 1,000 3,695E-03 0,028932 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 1,000 3,695E-03 0,02883957 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 1,000 3,695E-03 0,02874772 ! positive regulation of protein import into nucleus GO:0042307 34 16 1,000 3,695E-03 0,02865646 ! neuron recognition GO:0008038 40 16 1,000 3,695E-03 0,02856577 ! negative regulation of tissue remodeling GO:0034104 37 16 1,000 3,695E-03 0,02847566 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 1,000 3,695E-03 0,02838611 ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 3,695E-03 0,02829713 ! glucose catabolic process GO:0006007 88 56 2,000 4,073E-03 0,0310935 ! regulation of protein catabolic process GO:0042176 126 56 2,000 4,073E-03 0,03099663 ! positive regulation of cell killing GO:0031343 36 17 1,000 4,172E-03 0,03165227 ! negative regulation of cell cycle process GO:0010948 35 17 1,000 4,172E-03 0,03155427 ! signal complex assembly GO:0007172 47 17 1,000 4,172E-03 0,03145688 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 1,000 4,172E-03 0,03136009 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 1,000 4,172E-03 0,0312639 GO:0002712|regulation of B cell mediated immunity, ! neutrophil chemotaxis GO:0030593 29 17 1,000 4,172E-03 0,03116829 ! negative regulation of homeostatic process GO:0032845 36 17 1,000 4,172E-03 0,03107326 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 1,000 4,172E-03 0,03097882 ! regulation of bone remodeling GO:0046850 143 57 2,000 4,281E-03 0,03169392 ! positive regulation of caspase activity GO:0043280 108 57 2,000 4,281E-03 0,03159817 GO:0010952|positive regulation of peptidase activity, ! heart morphogenesis GO:0003007 105 57 2,000 4,281E-03 0,031503 ! regulation of tissue remodeling GO:0034103 146 58 2,000 4,496E-03 0,03298381 ! positive regulation of organelle organization GO:0010638 108 58 2,000 4,496E-03 0,03288506 ! positive regulation of protein complex assembly GO:0031334 34 18 1,000 4,676E-03 0,03409881 ! limbic system development GO:0021761 40 18 1,000 4,676E-03 0,03399732 ! positive regulation of proteolysis GO:0045862 36 18 1,000 4,676E-03 0,03389644 ! epidermis morphogenesis GO:0048730 43 18 1,000 4,676E-03 0,03379615 ! response to retinoic acid GO:0032526 31 18 1,000 4,676E-03 0,03369646 ! cell-substrate junction assembly GO:0007044 56 18 1,000 4,676E-03 0,03359735 ! negative regulation of protein catabolic process GO:0042177 42 18 1,000 4,676E-03 0,03349883 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 1,000 4,676E-03 0,03340088 ! regulation of immunoglobulin production GO:0002637 49 18 1,000 4,676E-03 0,0333035 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 1,000 4,676E-03 0,03320669 ! nerve development GO:0021675 34 18 1,000 4,676E-03 0,03311044 ! defense response to virus GO:0051607 43 18 1,000 4,676E-03 0,03301474 ! positive regulation of synaptic transmission GO:0050806 35 18 1,000 4,676E-03 0,0329196 ! DNA catabolic process GO:0006308 94 60 2,000 4,945E-03 0,03471262 ! negative regulation of response to stimulus GO:0048585 106 61 2,000 5,179E-03 0,0362522 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 1,000 5,206E-03 0,0363406 ! response to vitamin A GO:0033189 32 19 1,000 5,206E-03 0,03623707 ! neuromuscular junction development GO:0007528 43 19 1,000 5,206E-03 0,03613412 ! regulation of endothelial cell migration GO:0010594 45 19 1,000 5,206E-03 0,03603176 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 1,000 5,206E-03 0,03592997 ! cellular pigmentation GO:0033059 37 19 1,000 5,206E-03 0,03582876 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 1,000 5,206E-03 0,03572812 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 1,000 5,206E-03 0,03562804 ! viral reproductive process GO:0022415 132 62 2,000 5,42E-03 0,03698353 ! regulation of mitosis GO:0007088 112 63 2,000 5,667E-03 0,03856369 GO:0051783|regulation of nuclear division, ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 1,000 5,763E-03 0,03910996 ! positive regulation of ossification GO:0045778 50 20 1,000 5,763E-03 0,03900163 ! phosphoinositide phosphorylation GO:0046854 40 20 1,000 5,763E-03 0,03889389 ! protein amino acid acetylation GO:0006473 41 20 1,000 5,763E-03 0,03878674 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 1,000 5,763E-03 0,03868018 ! response to vitamin GO:0033273 36 20 1,000 5,763E-03 0,03857421 ! regulation of carbohydrate metabolic process GO:0006109 37 20 1,000 5,763E-03 0,03846882 GO:0010675|regulation of cellular carbohydrate metabolic process, ! response to alkaloid GO:0043279 38 20 1,000 5,763E-03 0,038364 ! pancreas development GO:0031016 40 20 1,000 5,763E-03 0,03825975 ! actin filament bundle formation GO:0051017 47 20 1,000 5,763E-03 0,03815606 ! positive regulation of neurological system process GO:0031646 39 20 1,000 5,763E-03 0,03805294 ! cell-cell junction organization GO:0045216 43 20 1,000 5,763E-03 0,03795037 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 1,000 5,763E-03 0,03784835 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 1,000 5,763E-03 0,03774688 ! regulation of cell killing GO:0031341 46 21 1,000 6,346E-03 0,0414531 ! lipid phosphorylation GO:0046834 43 21 1,000 6,346E-03 0,04134256 ! cellular macromolecular complex disassembly GO:0034623 44 21 1,000 6,346E-03 0,0412326 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 1,000 6,346E-03 0,04112323 ! collagen fibril organization GO:0030199 62 21 1,000 6,346E-03 0,04101444 ! myeloid cell differentiation GO:0030099 126 67 2,000 6,723E-03 0,04333896 ! positive regulation of protein catabolic process GO:0045732 44 22 1,000 6,955E-03 0,0447107 ! positive regulation of bone remodeling GO:0046852 54 22 1,000 6,955E-03 0,04459335 GO:0034105|positive regulation of tissue remodeling, ! inactivation of MAPK activity GO:0000188 45 22 1,000 6,955E-03 0,04447661 ! central nervous system neuron development GO:0021954 47 22 1,000 6,955E-03 0,04436048 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 1,000 6,955E-03 0,04424496 ! positive regulation of locomotion GO:0040017 44 22 1,000 6,955E-03 0,04413004 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! G1 phase GO:0051318 44 22 1,000 6,955E-03 0,04401571 ! positive regulation of adaptive immune response GO:0002821 42 22 1,000 6,955E-03 0,04390198 ! positive regulation of intracellular transport GO:0032388 42 22 1,000 6,955E-03 0,04378883 ! activation of JUN kinase activity GO:0007257 47 22 1,000 6,955E-03 0,04367626 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 1,000 6,955E-03 0,04356427 ! protein stabilization GO:0050821 41 22 1,000 6,955E-03 0,04345285 ! hexose catabolic process GO:0019320 113 68 2,000 7,005E-03 0,0436538 ! negative regulation of ligase activity GO:0051352 116 68 2,000 7,005E-03 0,04354272 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! viral reproduction GO:0016032 142 68 2,000 7,005E-03 0,04343221 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 2,000 7,005E-03 0,04332225 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 2,000 7,293E-03 0,04498975 ! urogenital system development GO:0001655 149 69 2,000 7,293E-03 0,04487642 ! homeostasis of number of cells GO:0048872 131 69 2,000 7,293E-03 0,04476367 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 2,000 7,293E-03 0,04465148 ! developmental maturation GO:0021700 128 69 2,000 7,293E-03 0,04453985 ! positive regulation of DNA replication GO:0045740 44 23 1,000 7,588E-03 0,04623105 ! viral genome replication GO:0019079 44 23 1,000 7,588E-03 0,04611605 ! regulation of chemotaxis GO:0050920 45 23 1,000 7,588E-03 0,04600161 ! regulation of cell-matrix adhesion GO:0001952 81 23 1,000 7,588E-03 0,04588775 GO:0010810|regulation of cell-substrate adhesion, ! carbohydrate transport GO:0008643 114 72 2,000 8,198E-03 0,04945375 ! actin filament organization GO:0007015 167 72 2,000 8,198E-03 0,04933194 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 2,000 8,198E-03 0,04921073 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 2,000 8,198E-03 0,04909012 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 1,000 8,247E-03 0,04926275 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 1,000 8,247E-03 0,0491426 ! positive regulation of cytoskeleton organization GO:0051495 52 24 1,000 8,247E-03 0,04902303 ! sex determination GO:0007530 48 24 1,000 8,247E-03 0,04890404 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 1,000 8,247E-03 0,04878563 GO:0002708|positive regulation of lymphocyte mediated immunity, ! pallium development GO:0021543 56 24 1,000 8,247E-03 0,04866779 ! negative regulation of catabolic process GO:0009895 52 24 1,000 8,247E-03 0,04855052 ! regulation of caspase activity GO:0043281 136 74 2,000 8,837E-03 0,05189848 ! positive regulation of fibroblast proliferation GO:0048146 48 25 1,000 8,931E-03 0,05232318 ! leukocyte adhesion GO:0007159 55 25 1,000 8,931E-03 0,052198 ! vasculogenesis GO:0001570 49 25 1,000 8,931E-03 0,05207342 ! receptor metabolic process GO:0043112 53 25 1,000 8,931E-03 0,05194944 ! regulation of behavior GO:0050795 48 25 1,000 8,931E-03 0,05182604 ! regulation of alpha-beta T cell activation GO:0046634 48 25 1,000 8,931E-03 0,05170323 ! interaction with host GO:0051701 66 25 1,000 8,931E-03 0,051581 ! lymphocyte proliferation GO:0046651 55 25 1,000 8,931E-03 0,05145935 ! immunoglobulin production GO:0002377 62 25 1,000 8,931E-03 0,05133827 GO:0002440|production of molecular mediator of immune response, ! leukocyte homeostasis GO:0001776 50 25 1,000 8,931E-03 0,05121776 ! protein tetramerization GO:0051262 57 25 1,000 8,931E-03 0,05109781 ! reproductive structure development GO:0048608 131 75 2,000 9,168E-03 0,05232768 ! eye development GO:0001654 155 75 2,000 9,168E-03 0,05220571 ! myelination GO:0042552 50 26 1,000 9,639E-03 0,05476468 ! macromolecular complex disassembly GO:0032984 54 26 1,000 9,639E-03 0,05463762 ! regulation of transcription factor import into nucleus GO:0042990 58 26 1,000 9,639E-03 0,05451114 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 1,000 9,639E-03 0,05438525 ! negative regulation of cell development GO:0010721 83 26 1,000 9,639E-03 0,05425994 GO:0050768|negative regulation of neurogenesis, ! positive regulation of nuclear division GO:0051785 41 26 1,000 9,639E-03 0,0541352 GO:0045840|positive regulation of mitosis, ! telomere organization GO:0032200 46 26 1,000 9,639E-03 0,05401104 GO:0000723|telomere maintenance, ! positive regulation of JUN kinase activity GO:0043507 59 26 1,000 9,639E-03 0,05388745 ! regulation of endopeptidase activity GO:0052548 141 77 2,000 9,849E-03 0,05493505 ! positive regulation of ligase activity GO:0051351 130 77 2,000 9,849E-03 0,05480991 ! monosaccharide catabolic process GO:0046365 125 77 2,000 9,849E-03 0,05468535 ! positive regulation of lymphocyte activation GO:0051251 142 78 2,000 0,01020079 0,05650911 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 1,000 0,01037163 0,05732553 ! regulation of endothelial cell proliferation GO:0001936 60 27 1,000 0,01037163 0,05719613 ! leukocyte proliferation GO:0070661 59 27 1,000 0,01037163 0,05706731 GO:0032943|mononuclear cell proliferation, ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 2,000 0,01092567 0,05998071 ! regulation of fibroblast proliferation GO:0048145 56 28 1,000 0,01112781 0,06095347 ! protein amino acid acylation GO:0043543 59 28 1,000 0,01112781 0,06081711 ! positive regulation of T cell differentiation GO:0045582 48 28 1,000 0,01112781 0,06068136 ! peptidyl-tyrosine modification GO:0018212 57 28 1,000 0,01112781 0,06054621 ! glutathione metabolic process GO:0006749 42 28 1,000 0,01112781 0,06041167 ! regulation of peptidase activity GO:0052547 150 82 2,000 0,01167963 0,06326683 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 1,000 0,01190757 0,06435884 ! cellular iron ion homeostasis GO:0006879 57 29 1,000 0,01190757 0,06421676 ! catechol metabolic process GO:0009712 55 29 1,000 0,01190757 0,06407532 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! regulation of production of molecular mediator of immune response GO:0002700 69 29 1,000 0,01190757 0,06393449 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 1,000 0,01190757 0,06379429 ! somitogenesis GO:0001756 52 29 1,000 0,01190757 0,06365469 ! phenol metabolic process GO:0018958 56 30 1,000 0,0127106 0,06779914 ! immune response-activating signal transduction GO:0002757 58 30 1,000 0,0127106 0,06765143 GO:0002764|immune response-regulating signal transduction, ! positive regulation of multicellular organism growth GO:0040018 55 30 1,000 0,0127106 0,06750436 ! neurotransmitter secretion GO:0007269 55 30 1,000 0,0127106 0,06735793 ! cholesterol metabolic process GO:0008203 148 85 2,000 0,01286549 0,06803114 ! regulation of neuron differentiation GO:0045664 187 85 2,000 0,01286549 0,0678842 ! positive regulation of cell activation GO:0050867 161 86 2,000 0,0132755 0,06989665 GO:0002696|positive regulation of leukocyte activation, ! iron ion homeostasis GO:0055072 60 31 1,000 0,01353663 0,07111824 ! erythrocyte differentiation GO:0030218 62 31 1,000 0,01353663 0,07096562 ! ensheathment of neurons GO:0007272 64 31 1,000 0,01353663 0,07081366 GO:0008366|axon ensheathment, ! response to heat GO:0009408 54 31 1,000 0,01353663 0,07066235 ! positive regulation of immune effector process GO:0002699 78 31 1,000 0,01353663 0,07051169 ! alcohol catabolic process GO:0046164 142 87 2,000 0,01369291 0,07117398 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 1,000 0,01438535 0,07461448 ! positive regulation of T cell proliferation GO:0042102 60 32 1,000 0,01438535 0,0744564 ! response to mechanical stimulus GO:0009612 60 32 1,000 0,01438535 0,07429898 ! regulation of protein import into nucleus GO:0042306 69 32 1,000 0,01438535 0,07414223 ! peripheral nervous system development GO:0007422 68 32 1,000 0,01438535 0,07398615 ! hindbrain development GO:0030902 65 32 1,000 0,01438535 0,07383071 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 1,000 0,01438535 0,07367593 ! positive regulation of neurogenesis GO:0050769 72 33 1,000 0,0152565 0,07797412 ! leukocyte chemotaxis GO:0030595 55 33 1,000 0,0152565 0,07781133 GO:0060326|cell chemotaxis, ! negative regulation of protein transport GO:0051224 74 33 1,000 0,0152565 0,07764922 ! ossification GO:0001503 205 91 2,000 0,0154368 0,07840354 ! bone development GO:0060348 206 92 2,000 0,01589141 0,08054507 ! inner ear morphogenesis GO:0042472 51 34 1,000 0,01614978 0,08168514 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 1,000 0,01614978 0,08151636 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 2,000 0,01635351 0,08237447 GO:0010498|proteasomal protein catabolic process, ! sterol metabolic process GO:0016125 166 94 2,000 0,01682309 0,08456547 ! regulation of synaptic plasticity GO:0048167 78 35 1,000 0,01706493 0,08560496 ! regulation of striated muscle tissue development GO:0016202 81 35 1,000 0,01706493 0,08542954 ! telencephalon development GO:0021537 81 35 1,000 0,01706493 0,08525484 ! calcium-mediated signaling GO:0019722 67 35 1,000 0,01706493 0,08508085 ! biogenic amine biosynthetic process GO:0042401 65 35 1,000 0,01706493 0,08490757 ! placenta development GO:0001890 53 35 1,000 0,01706493 0,08473499 ! regulation of muscle development GO:0048634 82 36 1,000 0,01800165 0,08920495 ! mitotic sister chromatid segregation GO:0000070 63 36 1,000 0,01800165 0,08902437 ! regulation of proteolysis GO:0030162 77 36 1,000 0,01800165 0,08884453 ! negative regulation of hydrolase activity GO:0051346 66 36 1,000 0,01800165 0,08866541 ! forebrain development GO:0030900 210 98 2,000 0,01877653 0,09229592 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 1,000 0,01895969 0,09300909 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! regulation of smooth muscle cell proliferation GO:0048660 64 37 1,000 0,01895969 0,09282269 ! negative regulation of cell adhesion GO:0007162 94 37 1,000 0,01895969 0,09263705 ! sister chromatid segregation GO:0000819 65 37 1,000 0,01895969 0,09245215 ! maintenance of protein location in cell GO:0032507 89 37 1,000 0,01895969 0,09226798 ! skeletal muscle tissue development GO:0007519 223 100 2,000 0,01979842 0,09615811 GO:0060538|skeletal muscle organ development, ! positive regulation of immune response GO:0050778 175 100 2,000 0,01979842 0,09596732 ! embryonic skeletal system morphogenesis GO:0048704 68 38 1,000 0,01993877 0,09645625 ! glycogen metabolic process GO:0005977 63 38 1,000 0,01993877 0,09626562 ! mitotic cell cycle checkpoint GO:0007093 76 39 1,000 0,02093861 0,10089354 ! regulation of lymphocyte mediated immunity GO:0002706 79 39 1,000 0,02093861 0,10069493 ! erythrocyte homeostasis GO:0034101 75 39 1,000 0,02093861 0,1004971 ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 1,000 0,02093861 0,10030005 ! glucan metabolic process GO:0044042 64 39 1,000 0,02093861 0,10010376 GO:0006073|cellular glucan metabolic process, ! mammary gland development GO:0030879 93 40 1,000 0,02195896 0,10477682 ! regulation of action potential in neuron GO:0019228 80 40 1,000 0,02195896 0,10457257 ! establishment or maintenance of cell polarity GO:0007163 96 41 1,000 0,02299954 0,10931494 ! gliogenesis GO:0042063 91 41 1,000 0,02299954 0,10910268 ! mesenchymal cell development GO:0014031 94 41 1,000 0,02299954 0,10889124 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! maintenance of protein location GO:0045185 95 41 1,000 0,02299954 0,10868062 ! regulation of intracellular protein transport GO:0033157 86 42 1,000 0,0240601 0,11347264 ! T cell differentiation GO:0030217 93 42 1,000 0,0240601 0,113254 ! regulation of leukocyte mediated immunity GO:0002703 84 42 1,000 0,0240601 0,11303621 ! cytokinesis GO:0000910 84 42 1,000 0,0240601 0,11281925 ! positive regulation of transcription factor activity GO:0051091 71 43 1,000 0,02514038 0,1176589 GO:0090047|positive regulation of transcription regulator activity, ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 1,000 0,02514038 0,11743393 ! calcium-dependent cell-cell adhesion GO:0016339 56 43 1,000 0,02514038 0,11720982 ! striated muscle cell differentiation GO:0051146 91 43 1,000 0,02514038 0,11698656 ! segmentation GO:0035282 78 43 1,000 0,02514038 0,11676415 ! regulation of myeloid cell differentiation GO:0045637 105 43 1,000 0,02514038 0,11654259 ! positive regulation of response to external stimulus GO:0032103 88 44 1,000 0,02624011 0,12141023 ! branching morphogenesis of a tube GO:0048754 102 45 1,000 0,02735905 0,12634814 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 1,000 0,02735905 0,12610975 ! developmental growth GO:0048589 88 45 1,000 0,02735905 0,12587226 ! maintenance of location in cell GO:0051651 101 45 1,000 0,02735905 0,12563566 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 0,0282334 0,12940751 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 0,0282334 0,12916517 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 0,0282334 0,12892374 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,0282334 0,12868321 ! positive regulation of helicase activity GO:0051096 12 5 0,000 0,0282334 0,12844358 ! neuron fate determination GO:0048664 7 5 0,000 0,0282334 0,12820484 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,0282334 0,12796698 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 0,0282334 0,12773 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 0,0282334 0,1274939 ! polyol transport GO:0015791 12 5 0,000 0,0282334 0,12725867 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,0282334 0,12702431 ! response to superoxide GO:0000303 10 5 0,000 0,0282334 0,12679081 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 0,0282334 0,12655817 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 0,0282334 0,12632638 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,0282334 0,12609543 ! female meiosis GO:0007143 10 5 0,000 0,0282334 0,12586533 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 0,0282334 0,12563607 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,0282334 0,12540764 ! hypothalamus development GO:0021854 9 5 0,000 0,0282334 0,12518004 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 0,0282334 0,12495326 ! cobalt ion transport GO:0006824 11 5 0,000 0,0282334 0,12472731 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 0,0282334 0,12450217 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 0,0282334 0,12427784 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,0282334 0,12405432 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,0282334 0,1238316 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 0,0282334 0,12360968 ! embryonic camera-type eye development GO:0031076 12 5 0,000 0,0282334 0,12338855 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,0282334 0,12316822 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,0282334 0,12294867 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 0,0282334 0,1227299 ! transposition GO:0032196 9 5 0,000 0,0282334 0,1225119 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 0,0282334 0,12229468 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 0,000 0,0282334 0,12207823 ! negative chemotaxis GO:0050919 16 5 0,000 0,0282334 0,12186255 ! positive regulation of histone modification GO:0031058 6 5 0,000 0,0282334 0,12164762 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,0282334 0,12143345 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 0,0282334 0,12122004 ! behavioral response to pain GO:0048266 10 5 0,000 0,0282334 0,12100737 ! clathrin coat assembly GO:0048268 15 5 0,000 0,0282334 0,12079545 ! Notch receptor processing GO:0007220 11 5 0,000 0,0282334 0,12058427 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,0282334 0,12037383 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 0,0282334 0,12016411 ! micturition GO:0060073 9 5 0,000 0,0282334 0,11995513 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,0282334 0,11974688 ! copulation GO:0007620 9 5 0,000 0,0282334 0,11953934 ! glial cell fate commitment GO:0021781 14 5 0,000 0,0282334 0,11933253 ! protein maturation by protein folding GO:0022417 14 5 0,000 0,0282334 0,11912643 ! bioluminescence GO:0008218 9 5 0,000 0,0282334 0,11892104 ! spermidine metabolic process GO:0008216 7 5 0,000 0,0282334 0,11871635 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,0282334 0,11851237 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,0282334 0,11830909 ! apoptotic cell clearance GO:0043277 23 5 0,000 0,0282334 0,11810651 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,0282334 0,11790462 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 0,0282334 0,11770342 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,0282334 0,1175029 ! grooming behavior GO:0007625 6 5 0,000 0,0282334 0,11730306 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 0,0282334 0,11710391 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,0282334 0,11690543 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 0,0282334 0,11670762 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,0282334 0,11651048 ! response to protozoan GO:0001562 13 5 0,000 0,0282334 0,116314 ! lymph vessel development GO:0001945 10 5 0,000 0,0282334 0,11611818 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 0,0282334 0,11592303 ! endochondral ossification GO:0001958 17 5 0,000 0,0282334 0,11572853 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,0282334 0,11553468 ! single strand break repair GO:0000012 8 5 0,000 0,0282334 0,11534147 ! parathyroid gland development GO:0060017 14 5 0,000 0,0282334 0,11514892 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,0282334 0,114957 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,0282334 0,11476573 ! cytokine secretion GO:0050663 15 5 0,000 0,0282334 0,11457509 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 0,0282334 0,11438508 ! ceramide catabolic process GO:0046514 7 5 0,000 0,0282334 0,1141957 ! skeletal myofibril assembly GO:0014866 12 5 0,000 0,0282334 0,11400695 ! smooth muscle tissue development GO:0048745 32 5 0,000 0,0282334 0,11381881 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,0282334 0,1136313 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,0282334 0,11344441 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,0282334 0,11325813 ! cardiac muscle fiber development GO:0048739 12 5 0,000 0,0282334 0,11307246 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,0282334 0,1128874 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,0282334 0,11270294 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 0,0282334 0,11251909 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,0282334 0,11233583 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 0,0282334 0,11215317 ! glycine biosynthetic process GO:0006545 7 5 0,000 0,0282334 0,11197111 ! valine metabolic process GO:0006573 12 5 0,000 0,0282334 0,11178963 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 0,0282334 0,11160874 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 0,0282334 0,11142844 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 0,0282334 0,11124871 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 0,0282334 0,11106957 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 0,0282334 0,110891 ! polyol catabolic process GO:0046174 9 5 0,000 0,0282334 0,110713 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 0,0282334 0,11053558 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 0,0282334 0,11035872 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 0,0282334 0,11018243 ! muscle cell migration GO:0014812 8 5 0,000 0,0282334 0,1100067 ! mitochondrial fission GO:0000266 8 5 0,000 0,0282334 0,10983153 ! sister chromatid cohesion GO:0007062 15 5 0,000 0,0282334 0,10965692 ! response to tumor necrosis factor GO:0034612 10 5 0,000 0,0282334 0,10948286 ! mRNA transcription GO:0009299 10 5 0,000 0,0282334 0,10930935 ! nerve growth factor processing GO:0032455 9 5 0,000 0,0282334 0,1091364 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 0,0282334 0,10896398 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 0,0282334 0,10879212 ! anaerobic glycolysis GO:0019642 6 5 0,000 0,0282334 0,10862079 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,0282334 0,10845 ! monocyte activation GO:0042117 10 5 0,000 0,0282334 0,10827975 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,0282334 0,10811003 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,0282334 0,10794085 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,0282334 0,10777219 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 0,0282334 0,10760406 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,0282334 0,10743645 ! forebrain neuron development GO:0021884 13 5 0,000 0,0282334 0,10726937 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,0282334 0,1071028 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 0,0282334 0,10693675 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,0282334 0,10677121 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,0282334 0,10660619 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 0,0282334 0,10644167 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 0,0282334 0,10627766 ! lipid glycosylation GO:0030259 7 5 0,000 0,0282334 0,10611416 ! nucleobase transport GO:0015851 6 5 0,000 0,0282334 0,10595115 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,0282334 0,10578865 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 0,0282334 0,10562665 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 0,0282334 0,10546514 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 0,0282334 0,10530412 ! basic amino acid transport GO:0015802 12 5 0,000 0,0282334 0,1051436 ! cellular glucose homeostasis GO:0001678 6 5 0,000 0,0282334 0,10498356 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 0,0282334 0,10482401 ! actin nucleation GO:0045010 11 5 0,000 0,0282334 0,10466495 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,0282334 0,10450637 ! depurination GO:0045007 5 5 0,000 0,0282334 0,10434826 ! depyrimidination GO:0045008 10 5 0,000 0,0282334 0,10419064 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,0282334 0,10403349 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,0282334 0,10387681 ! zinc ion homeostasis GO:0055069 9 5 0,000 0,0282334 0,1037206 GO:0006882|cellular zinc ion homeostasis, ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 0,0282334 0,10356487 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,0282334 0,1034096 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,0282334 0,10325479 ! activated T cell proliferation GO:0050798 16 5 0,000 0,0282334 0,10310045 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,0282334 0,10294657 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 0,0282334 0,10279315 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,0282334 0,10264018 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,0282334 0,10248767 ! gamma-delta T cell activation GO:0046629 6 5 0,000 0,0282334 0,10233561 ! response to arsenic GO:0046685 11 5 0,000 0,0282334 0,102184 ! mast cell degranulation GO:0043303 7 5 0,000 0,0282334 0,10203284 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 0,0282334 0,10188213 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 0,0282334 0,10173186 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 0,0282334 0,10158203 ! response to mercury ion GO:0046689 8 5 0,000 0,0282334 0,10143265 ! response to cadmium ion GO:0046686 7 5 0,000 0,0282334 0,1012837 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 0,0282334 0,10113519 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 0,0282334 0,10098712 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 0,0282334 0,10083948 ! bile acid biosynthetic process GO:0006699 7 5 0,000 0,0282334 0,10069227 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 0,0282334 0,10054548 ! ganglioside catabolic process GO:0006689 12 5 0,000 0,0282334 0,10039913 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,0282334 0,1002532 ! decidualization GO:0046697 11 5 0,000 0,0282334 0,10010769 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 0,0282334 0,09996261 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 0,0282334 0,09981795 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 0,0282334 0,0996737 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 0,0282334 0,09952987 ! embryonic cleavage GO:0040016 6 5 0,000 0,0282334 0,09938646 ! peroxisome fission GO:0016559 5 5 0,000 0,0282334 0,09924346 ! histone demethylation GO:0016577 13 5 0,000 0,0282334 0,09910086 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 0,0282334 0,09895868 ! mitotic recombination GO:0006312 9 5 0,000 0,0282334 0,09881691 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 0,0282334 0,09867554 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,0282334 0,09853457 ! metaphase plate congression GO:0051310 7 5 0,000 0,0282334 0,09839401 ! regulation of sterol transport GO:0032371 7 5 0,000 0,0282334 0,09825385 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,0282334 0,09811408 ! enteric nervous system development GO:0048484 8 5 0,000 0,0282334 0,09797472 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 0,0282334 0,09783575 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 0,0282334 0,09769717 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 0,0282334 0,09755898 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,0282334 0,09742119 ! B cell homeostasis GO:0001782 13 5 0,000 0,0282334 0,09728378 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 0,0282334 0,09714676 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,0282334 0,09701013 ! metaphase GO:0051323 11 5 0,000 0,0282334 0,09687388 ! melatonin biosynthetic process GO:0030187 7 5 0,000 0,0282334 0,09673801 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 0,0282334 0,09660252 ! cellular response to nutrient GO:0031670 8 5 0,000 0,0282334 0,09646742 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,0282334 0,09633268 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 0,0282334 0,09619833 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 0,0282334 0,09606435 ! definitive hemopoiesis GO:0060216 14 5 0,000 0,0282334 0,09593074 ! response to redox state GO:0051775 6 5 0,000 0,0282334 0,0957975 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 0,0282334 0,09566463 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 0,0282334 0,09553214 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,0282334 0,0954 ! brown fat cell differentiation GO:0050873 7 5 0,000 0,0282334 0,09526823 ! regulation of telomerase activity GO:0051972 7 5 0,000 0,0282334 0,09513683 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,0282334 0,09500579 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 0,0282334 0,09487511 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,0282334 0,09474478 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 0,0282334 0,09461482 ! striatum development GO:0021756 14 5 0,000 0,0282334 0,09448521 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,0282334 0,09435595 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,0282334 0,09422705 ! neural plate morphogenesis GO:0001839 7 5 0,000 0,0282334 0,0940985 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 0,0282334 0,0939703 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,0282334 0,09384245 ! T cell activation during immune response GO:0002286 9 5 0,000 0,0282334 0,09371495 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,0282334 0,09358779 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,0282334 0,09346098 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 0,0282334 0,09333451 ! neuroprotection GO:0043526 8 5 0,000 0,0282334 0,09320838 ! regulation of sensory perception GO:0051931 8 5 0,000 0,0282334 0,09308259 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,0282334 0,09295715 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,0282334 0,09283203 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 0,0282334 0,09270726 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 0,0282334 0,09258282 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,0282334 0,09245872 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 0,0282334 0,09233494 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,0282334 0,0922115 ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 0,0282334 0,09208839 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,0282334 0,0919656 ! spindle assembly GO:0051225 6 5 0,000 0,0282334 0,09184314 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,0282334 0,09172101 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,0282334 0,09159921 ! protein palmitoylation GO:0018345 12 5 0,000 0,0282334 0,09147772 ! drug metabolic process GO:0017144 7 5 0,000 0,0282334 0,09135656 ! phospholipid scrambling GO:0017121 8 5 0,000 0,0282334 0,09123572 ! organ regeneration GO:0031100 7 5 0,000 0,0282334 0,09111519 ! carnitine metabolic process GO:0009437 8 5 0,000 0,0282334 0,09099499 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,0282334 0,0908751 ! regulation of actin filament polymerization GO:0030833 99 46 1,000 0,02849694 0,09160268 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 1,000 0,02849694 0,09148231 ! regulation of gene-specific transcription GO:0032583 102 46 1,000 0,02849694 0,09136225 ! leukocyte migration GO:0050900 75 46 1,000 0,02849694 0,09124251 ! polysaccharide biosynthetic process GO:0000271 79 46 1,000 0,02849694 0,09112308 ! positive regulation of protein transport GO:0051222 80 46 1,000 0,02849694 0,09100397 ! endosome transport GO:0016197 127 48 1,000 0,03082858 0,09832143 ! vascular process in circulatory system GO:0003018 85 48 1,000 0,03082858 0,09819324 ! regulation of adaptive immune response GO:0002819 92 48 1,000 0,03082858 0,09806538 ! detection of stimulus involved in sensory perception GO:0050906 75 49 1,000 0,03202183 0,10172863 ! JNK cascade GO:0007254 106 49 1,000 0,03202183 0,10159652 ! regulation of action potential GO:0001508 102 50 1,000 0,03323304 0,1053026 ! endocrine system development GO:0035270 109 50 1,000 0,03323304 0,1051662 ! regulation of ossification GO:0030278 123 50 1,000 0,03323304 0,10503015 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,03378417 0,106634 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,03378417 0,10649641 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 0,03378417 0,10635917 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 0,03378417 0,10622229 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,03378417 0,10608576 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 0,03378417 0,10594958 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 0,03378417 0,10581374 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 0,03378417 0,10567826 ! response to oxygen radical GO:0000305 11 6 0,000 0,03378417 0,10554312 ! positive regulation of axon extension GO:0045773 13 6 0,000 0,03378417 0,10540833 ! myoblast cell fate commitment GO:0048625 18 6 0,000 0,03378417 0,10527388 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 0,03378417 0,10513977 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 0,03378417 0,105006 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,03378417 0,10487258 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,03378417 0,10473949 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 0,03378417 0,10460674 ! forebrain regionalization GO:0021871 9 6 0,000 0,03378417 0,10447433 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,03378417 0,10434225 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,03378417 0,1042105 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 0,03378417 0,10407909 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,03378417 0,10394801 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 0,03378417 0,10381726 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 0,03378417 0,10368683 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,03378417 0,10355674 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 0,03378417 0,10342697 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 0,03378417 0,10329752 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,03378417 0,1031684 ! malate metabolic process GO:0006108 13 6 0,000 0,03378417 0,1030396 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 0,03378417 0,10291112 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 0,03378417 0,10278296 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 0,03378417 0,10265512 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 0,03378417 0,1025276 ! protein refolding GO:0042026 15 6 0,000 0,03378417 0,1024004 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,03378417 0,10227351 ! opsonization GO:0008228 8 6 0,000 0,03378417 0,10214693 ! mating behavior GO:0007617 7 6 0,000 0,03378417 0,10202067 ! erythrocyte maturation GO:0043249 8 6 0,000 0,03378417 0,10189472 ! embryonic hemopoiesis GO:0035162 16 6 0,000 0,03378417 0,10176907 ! protein amino acid dealkylation GO:0008214 15 6 0,000 0,03378417 0,10164374 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 0,03378417 0,10151872 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 0,03378417 0,101394 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,03378417 0,10126959 ! response to interferon-gamma GO:0034341 16 6 0,000 0,03378417 0,10114549 ! toxin metabolic process GO:0009404 11 6 0,000 0,03378417 0,10102169 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,03378417 0,10089819 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 0,03378417 0,10077499 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 0,03378417 0,1006521 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 0,03378417 0,1005295 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 13 6 0,000 0,03378417 0,1004072 ! cGMP-mediated signaling GO:0019934 14 6 0,000 0,03378417 0,1002852 ! dorsal spinal cord development GO:0021516 10 6 0,000 0,03378417 0,10016349 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,03378417 0,10004208 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 0,03378417 0,09992097 ! sphingoid catabolic process GO:0046521 8 6 0,000 0,03378417 0,09980014 ! protein lipoylation GO:0009249 10 6 0,000 0,03378417 0,09967961 ! transepithelial chloride transport GO:0030321 12 6 0,000 0,03378417 0,09955937 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 0,03378417 0,09943942 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,03378417 0,09931976 ! glutamate catabolic process GO:0006538 12 6 0,000 0,03378417 0,09920038 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 0,03378417 0,0990813 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,03378417 0,09896249 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 0,03378417 0,09884398 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,03378417 0,09872574 ! hyperosmotic response GO:0006972 10 6 0,000 0,03378417 0,09860779 ! L-serine biosynthetic process GO:0006564 7 6 0,000 0,03378417 0,09849012 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 0,03378417 0,09837273 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 0,03378417 0,09825562 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,03378417 0,09813879 ! urea metabolic process GO:0019627 7 6 0,000 0,03378417 0,09802223 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,03378417 0,09790595 ! neutrophil activation GO:0042119 7 6 0,000 0,03378417 0,09778995 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,03378417 0,09767422 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 0,03378417 0,09755877 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,03378417 0,09744359 ! paraxial mesoderm development GO:0048339 16 6 0,000 0,03378417 0,09732868 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 0,03378417 0,09721404 ! neuron apoptosis GO:0051402 15 6 0,000 0,03378417 0,09709967 ! T cell mediated immunity GO:0002456 17 6 0,000 0,03378417 0,09698557 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,03378417 0,09687174 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 0,03378417 0,09675817 ! carnitine transport GO:0015879 10 6 0,000 0,03378417 0,09664487 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,03378417 0,09653184 ! positive regulation of exocytosis GO:0045921 11 6 0,000 0,03378417 0,09641906 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 0,03378417 0,09630656 ! 5S class rRNA transcription GO:0042791 13 6 0,000 0,03378417 0,09619431 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,03378417 0,09608233 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 0,03378417 0,0959706 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 0,03378417 0,09585914 ! sodium ion homeostasis GO:0055078 12 6 0,000 0,03378417 0,09574793 ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 0,03378417 0,09563699 ! response to UV-C GO:0010225 14 6 0,000 0,03378417 0,0955263 ! astrocyte development GO:0014002 16 6 0,000 0,03378417 0,09541586 ! protein targeting to lysosome GO:0006622 12 6 0,000 0,03378417 0,09530568 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,03378417 0,09519575 ! interaction with symbiont GO:0051702 14 6 0,000 0,03378417 0,09508608 ! regulation of dendrite development GO:0050773 16 6 0,000 0,03378417 0,09497666 ! peptidyl-arginine modification GO:0018195 13 6 0,000 0,03378417 0,09486749 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 0,03378417 0,09475858 ! response to copper ion GO:0046688 10 6 0,000 0,03378417 0,09464991 ! response to exogenous dsRNA GO:0043330 13 6 0,000 0,03378417 0,09454149 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,03378417 0,09443332 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 0,03378417 0,09432539 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,03378417 0,09421772 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 0,03378417 0,09411028 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,03378417 0,0940031 ! nucleoside catabolic process GO:0009164 10 6 0,000 0,03378417 0,09389615 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,03378417 0,09378945 ! Schwann cell development GO:0014044 15 6 0,000 0,03378417 0,093683 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 0,03378417 0,09357678 ! response to pheromone GO:0019236 6 6 0,000 0,03378417 0,0934708 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 0,03378417 0,09336507 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 0,03378417 0,09325957 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 0,03378417 0,09315431 ! base conversion or substitution editing GO:0016553 6 6 0,000 0,03378417 0,09304929 ! subpallium development GO:0021544 15 6 0,000 0,03378417 0,0929445 ! neural tube patterning GO:0021532 8 6 0,000 0,03378417 0,09283995 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 0,03378417 0,09273564 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 0,03378417 0,09263156 ! maintenance of organ identity GO:0048496 9 6 0,000 0,03378417 0,09252771 ! G2 phase GO:0051319 16 6 0,000 0,03378417 0,0924241 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 0,03378417 0,09232072 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 0,03378417 0,09221756 ! oxygen homeostasis GO:0032364 10 6 0,000 0,03378417 0,09211464 ! establishment of planar polarity GO:0001736 7 6 0,000 0,03378417 0,09201195 ! regulation of mast cell activation GO:0033003 13 6 0,000 0,03378417 0,09190949 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,03378417 0,09180725 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 0,03378417 0,09170524 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,03378417 0,09160346 ! receptor internalization GO:0031623 11 6 0,000 0,03378417 0,09150191 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 0,03378417 0,09140058 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 0,03378417 0,09129947 ! neutrophil homeostasis GO:0001780 11 6 0,000 0,03378417 0,09119858 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,03378417 0,09109792 GO:0043011|myeloid dendritic cell differentiation, ! protein deubiquitination GO:0016579 16 6 0,000 0,03378417 0,09099749 ! negative regulation of neuroblast proliferation GO:0007406 25 6 0,000 0,03378417 0,09089727 ! protein destabilization GO:0031648 9 6 0,000 0,03378417 0,09079727 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 0,03378417 0,09069749 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,03378417 0,09059794 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 0,03378417 0,0904986 ! regulation of viral transcription GO:0046782 11 6 0,000 0,03378417 0,09039947 ! progesterone metabolic process GO:0042448 12 6 0,000 0,03378417 0,09030057 ! negative regulation of axon extension GO:0030517 24 6 0,000 0,03378417 0,09020188 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 0,03378417 0,09010341 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 0,03378417 0,09000515 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,03378417 0,0899071 ! determination of adult lifespan GO:0008340 17 6 0,000 0,03378417 0,08980927 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 0,03378417 0,08971165 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 0,03378417 0,08961424 ! neural plate development GO:0001840 9 6 0,000 0,03378417 0,08951705 ! catecholamine transport GO:0051937 9 6 0,000 0,03378417 0,08942006 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 0,03378417 0,08932329 ! sensory cilium assembly GO:0035058 10 6 0,000 0,03378417 0,08922672 ! organ or tissue specific immune response GO:0002251 8 6 0,000 0,03378417 0,08913037 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 0,03378417 0,08903422 ! maternal placenta development GO:0001893 12 6 0,000 0,03378417 0,08893828 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 0,03378417 0,08884254 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,03378417 0,08874701 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 0,03378417 0,08865169 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 0,03378417 0,08855657 ! positive regulation of coagulation GO:0050820 13 6 0,000 0,03378417 0,08846165 ! cellular anion homeostasis GO:0030002 11 6 0,000 0,03378417 0,08836694 GO:0055081|anion homeostasis, ! viral infectious cycle GO:0019058 104 51 1,000 0,03446196 0,0900434 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 1,000 0,03446196 0,0899472 ! peptide metabolic process GO:0006518 80 51 1,000 0,03446196 0,0898512 ! response to temperature stimulus GO:0009266 84 51 1,000 0,03446196 0,08975541 ! detection of abiotic stimulus GO:0009582 80 51 1,000 0,03446196 0,08965983 ! DNA-dependent DNA replication GO:0006261 82 52 1,000 0,03570837 0,09280378 ! histone modification GO:0016570 104 52 1,000 0,03570837 0,09270516 ! morphogenesis of a branching structure GO:0001763 116 52 1,000 0,03570837 0,09260675 ! chromatin remodeling GO:0006338 122 53 1,000 0,03697202 0,09578224 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 1,000 0,03697202 0,09568078 ! regulation of neuron apoptosis GO:0043523 117 53 1,000 0,03697202 0,09557953 ! cartilage development GO:0051216 99 53 1,000 0,03697202 0,09547849 ! synapse organization GO:0050808 102 53 1,000 0,03697202 0,09537767 ! activation of phospholipase C activity GO:0007202 110 54 1,000 0,03825268 0,09857732 GO:0010863|positive regulation of phospholipase C activity, ! embryonic skeletal system development GO:0048706 101 54 1,000 0,03825268 0,09847345 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 1,000 0,03825268 0,09836979 ! covalent chromatin modification GO:0016569 115 54 1,000 0,03825268 0,09826635 ! tRNA transcription GO:0009304 17 7 0,000 0,03930338 0,10085941 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 0,03930338 0,10075358 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 0,03930338 0,10064796 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,03930338 0,10054257 ! regulation of helicase activity GO:0051095 16 7 0,000 0,03930338 0,1004374 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 0,03930338 0,10033245 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,03930338 0,10022772 ! sleep GO:0030431 16 7 0,000 0,03930338 0,10012321 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,03930338 0,10001891 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 0,03930338 0,09991484 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,03930338 0,09981098 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,03930338 0,09970733 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,03930338 0,0996039 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,03930338 0,09950068 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,03930338 0,09939768 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,03930338 0,09929489 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,03930338 0,09919231 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,03930338 0,09908995 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,03930338 0,09898779 ! SMAD protein complex assembly GO:0007183 13 7 0,000 0,03930338 0,09888585 ! glycolipid transport GO:0046836 11 7 0,000 0,03930338 0,09878411 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,03930338 0,09868259 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,03930338 0,09858127 ! neuron adhesion GO:0007158 14 7 0,000 0,03930338 0,09848016 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,03930338 0,09837926 ! establishment of tissue polarity GO:0007164 8 7 0,000 0,03930338 0,09827857 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 0,03930338 0,09817808 ! pericardium development GO:0060039 16 7 0,000 0,03930338 0,09807779 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 0,03930338 0,09797771 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 0,03930338 0,09787784 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 0,03930338 0,09777817 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 0,03930338 0,0976787 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,03930338 0,09757943 ! lipoprotein transport GO:0042953 14 7 0,000 0,03930338 0,09748036 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,03930338 0,0973815 ! rhythmic behavior GO:0007622 17 7 0,000 0,03930338 0,09728284 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 0,03930338 0,09718437 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 0,03930338 0,09708611 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,03930338 0,09698804 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 0,03930338 0,09689017 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,03930338 0,0967925 ! regulation of odontogenesis GO:0042481 14 7 0,000 0,03930338 0,09669502 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,03930338 0,09659774 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 0,03930338 0,09650066 ! mechanosensory behavior GO:0007638 16 7 0,000 0,03930338 0,09640377 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 0,03930338 0,09630708 ! positive regulation of heart rate GO:0010460 11 7 0,000 0,03930338 0,09621058 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,03930338 0,09611427 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,03930338 0,09601816 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,03930338 0,09592224 ! spinal cord patterning GO:0021511 14 7 0,000 0,03930338 0,09582651 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 0,03930338 0,09573097 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,03930338 0,09563562 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,03930338 0,09554046 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 0,03930338 0,09544549 ! adrenal gland development GO:0030325 17 7 0,000 0,03930338 0,0953507 ! cysteine metabolic process GO:0006534 13 7 0,000 0,03930338 0,09525611 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 0,03930338 0,0951617 ! ovulation GO:0030728 10 7 0,000 0,03930338 0,09506748 ! adenohypophysis development GO:0021984 11 7 0,000 0,03930338 0,09497345 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 0,03930338 0,0948796 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 0,03930338 0,09478594 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 0,03930338 0,09469246 ! microtubule nucleation GO:0007020 21 7 0,000 0,03930338 0,09459917 ! proline biosynthetic process GO:0006561 10 7 0,000 0,03930338 0,09450606 ! tryptophan metabolic process GO:0006568 11 7 0,000 0,03930338 0,09441314 ! thyroid hormone generation GO:0006590 13 7 0,000 0,03930338 0,09432039 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 0,03930338 0,09422783 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,03930338 0,09413545 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,03930338 0,09404325 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,03930338 0,09395123 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,03930338 0,09385939 ! galactose metabolic process GO:0006012 13 7 0,000 0,03930338 0,09376773 ! vesicle fusion GO:0006906 20 7 0,000 0,03930338 0,09367625 ! response to dietary excess GO:0002021 8 7 0,000 0,03930338 0,09358495 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,03930338 0,09349383 ! intracellular pH reduction GO:0051452 13 7 0,000 0,03930338 0,09340288 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,03930338 0,09331211 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 0,03930338 0,09322151 ! organ growth GO:0035265 15 7 0,000 0,03930338 0,09313109 ! nucleoside transport GO:0015858 11 7 0,000 0,03930338 0,09304085 ! nucleoside salvage GO:0043174 11 7 0,000 0,03930338 0,09295078 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 0,03930338 0,09286089 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,03930338 0,09277117 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 0,03930338 0,09268162 ! parturition GO:0007567 16 7 0,000 0,03930338 0,09259225 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 0,03930338 0,09250304 ! rRNA modification GO:0000154 14 7 0,000 0,03930338 0,09241401 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,03930338 0,09232515 ! spindle checkpoint GO:0031577 16 7 0,000 0,03930338 0,09223646 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 0,03930338 0,09214794 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,03930338 0,0920596 ! monocyte differentiation GO:0030224 16 7 0,000 0,03930338 0,09197142 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,03930338 0,09188341 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,03930338 0,09179556 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 0,03930338 0,09170789 ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,03930338 0,09162038 ! G1 DNA damage checkpoint GO:0031571 20 7 0,000 0,03930338 0,09153304 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,03930338 0,09144587 ! fibrinolysis GO:0042730 11 7 0,000 0,03930338 0,09135886 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 0,000 0,03930338 0,09127201 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,03930338 0,09118534 ! eating behavior GO:0042755 8 7 0,000 0,03930338 0,09109882 ! B cell lineage commitment GO:0002326 21 7 0,000 0,03930338 0,09101247 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,03930338 0,09092629 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 0,03930338 0,09084026 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 0,03930338 0,0907544 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,03930338 0,0906687 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 0,03930338 0,09058317 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,03930338 0,09049779 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 0,03930338 0,09041258 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 0,03930338 0,09032752 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 0,03930338 0,09024263 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,03930338 0,0901579 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 0,03930338 0,09007332 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,03930338 0,0899889 ! histone ubiquitination GO:0016574 9 7 0,000 0,03930338 0,08990464 ! regulation of meiosis GO:0040020 12 7 0,000 0,03930338 0,08982054 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 0,03930338 0,0897366 ! T cell lineage commitment GO:0002360 16 7 0,000 0,03930338 0,08965281 ! regulation of lipid transport GO:0032368 14 7 0,000 0,03930338 0,08956918 ! membrane to membrane docking GO:0022614 14 7 0,000 0,03930338 0,0894857 ! transcription termination GO:0006353 14 7 0,000 0,03930338 0,08940238 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,03930338 0,08931922 ! anaphase GO:0051322 18 7 0,000 0,03930338 0,08923621 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 0,03930338 0,08915335 ! axonal fasciculation GO:0007413 19 7 0,000 0,03930338 0,08907065 ! negative regulation of nuclear division GO:0051784 15 7 0,000 0,03930338 0,0889881 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 0,03930338 0,0889057 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,03930338 0,08882346 GO:0015991|ATP hydrolysis coupled proton transport, ! diuresis GO:0030146 12 7 0,000 0,03930338 0,08874137 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,03930338 0,08865943 ! thiamin metabolic process GO:0006772 7 7 0,000 0,03930338 0,08857764 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,03930338 0,088496 ! antibiotic transport GO:0042891 9 7 0,000 0,03930338 0,08841451 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,03930338 0,08833317 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 0,03930338 0,08825198 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 0,03930338 0,08817094 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 0,03930338 0,08809005 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,03930338 0,08800931 ! melanin biosynthetic process GO:0042438 10 7 0,000 0,03930338 0,08792872 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 0,03930338 0,08784827 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,03930338 0,08776797 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 0,03930338 0,08768782 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,03930338 0,08760781 ! endosome to lysosome transport GO:0008333 12 7 0,000 0,03930338 0,08752795 ! protein modification by small protein removal GO:0070646 19 7 0,000 0,03930338 0,08744823 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 0,03930338 0,08736866 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,03930338 0,08728923 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 0,03930338 0,08720995 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,03930338 0,08713082 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,03930338 0,08705182 ! muscle adaptation GO:0043500 13 7 0,000 0,03930338 0,08697297 ! embryonic heart tube development GO:0035050 14 7 0,000 0,03930338 0,08689426 ! retina homeostasis GO:0001895 12 7 0,000 0,03930338 0,08681569 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 0,03930338 0,08673727 ! protein amino acid prenylation GO:0018346 19 7 0,000 0,03930338 0,08665899 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 0,03930338 0,08658085 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 0,03930338 0,08650285 ! positive regulation of phospholipase activity GO:0010518 111 55 1,000 0,03955011 0,08696753 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 1,000 0,03955011 0,08688932 ! cell recognition GO:0008037 98 55 1,000 0,03955011 0,08681126 ! regulation of multicellular organism growth GO:0040014 90 55 1,000 0,03955011 0,08673333 ! cell maturation GO:0048469 107 55 1,000 0,03955011 0,08665554 ! regulation of protein polymerization GO:0032271 117 55 1,000 0,03955011 0,08657789 ! skeletal muscle fiber development GO:0048741 130 56 1,000 0,04086409 0,08937419 ! regulation of DNA replication GO:0006275 105 56 1,000 0,04086409 0,08929425 ! muscle fiber development GO:0048747 131 57 1,000 0,04219437 0,09211873 ! regulation of phospholipase activity GO:0010517 113 57 1,000 0,04219437 0,09203648 ! nucleotide-excision repair GO:0006289 91 57 1,000 0,04219437 0,09195438 ! regulation of intracellular transport GO:0032386 108 57 1,000 0,04219437 0,09187242 ! regulation of actin filament length GO:0030832 118 58 1,000 0,04354075 0,09471954 ! cellular polysaccharide metabolic process GO:0044264 93 58 1,000 0,04354075 0,09463527 ! aging GO:0007568 112 58 1,000 0,04354075 0,09455115 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 1,000 0,04354075 0,09446718 ! positive regulation of lipase activity GO:0060193 115 58 1,000 0,04354075 0,09438336 ! maintenance of location GO:0051235 124 58 1,000 0,04354075 0,09429968 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,04479122 0,09692201 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,04479122 0,09683624 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 0,04479122 0,09675062 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 0,04479122 0,09666515 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,04479122 0,09657984 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,04479122 0,09649467 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,04479122 0,09640965 ! male meiosis GO:0007140 9 8 0,000 0,04479122 0,09632478 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,04479122 0,09624007 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,04479122 0,0961555 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,04479122 0,09607108 ! meiotic prophase I GO:0007128 14 8 0,000 0,04479122 0,0959868 ! response to zinc ion GO:0010043 12 8 0,000 0,04479122 0,09590268 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,04479122 0,0958187 ! oligopeptide transport GO:0006857 16 8 0,000 0,04479122 0,09573487 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,04479122 0,09565118 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,04479122 0,09556765 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,04479122 0,09548425 ! signal peptide processing GO:0006465 12 8 0,000 0,04479122 0,09540101 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,04479122 0,0953179 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,04479122 0,09523495 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,04479122 0,09515213 ! succinate metabolic process GO:0006105 17 8 0,000 0,04479122 0,09506947 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,04479122 0,09498694 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,04479122 0,09490456 ! estrogen metabolic process GO:0008210 17 8 0,000 0,04479122 0,09482232 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,04479122 0,09474022 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,04479122 0,09465827 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,04479122 0,09457645 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,04479122 0,09449478 ! reflex GO:0060004 17 8 0,000 0,04479122 0,09441325 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,04479122 0,09433186 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,04479122 0,09425061 ! hemoglobin metabolic process GO:0020027 14 8 0,000 0,04479122 0,0941695 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,04479122 0,09408852 ! pigment granule organization GO:0048753 17 8 0,000 0,04479122 0,09400769 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,04479122 0,093927 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,04479122 0,09384644 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,04479122 0,09376603 ! astrocyte differentiation GO:0048708 19 8 0,000 0,04479122 0,09368575 ! histidine catabolic process GO:0006548 10 8 0,000 0,04479122 0,09360561 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,04479122 0,0935256 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,04479122 0,09344573 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,04479122 0,093366 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 13 8 0,000 0,04479122 0,09328641 ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,04479122 0,09320695 ! regulation of pigmentation during development GO:0048070 25 8 0,000 0,04479122 0,09312762 ! melanin metabolic process GO:0006582 17 8 0,000 0,04479122 0,09304843 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,04479122 0,09296938 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,04479122 0,09289045 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,04479122 0,09281167 ! macrophage activation GO:0042116 13 8 0,000 0,04479122 0,09273301 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,04479122 0,09265449 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! positive regulation of insulin secretion GO:0032024 17 8 0,000 0,04479122 0,0925761 ! purine salvage GO:0043101 12 8 0,000 0,04479122 0,09249785 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,04479122 0,09241973 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,04479122 0,09234173 ! osteoblast development GO:0002076 17 8 0,000 0,04479122 0,09226387 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,04479122 0,09218615 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,04479122 0,09210855 ! Schwann cell differentiation GO:0014037 21 8 0,000 0,04479122 0,09203108 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,04479122 0,09195374 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,04479122 0,09187654 ! response to UV-B GO:0010224 17 8 0,000 0,04479122 0,09179946 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,04479122 0,09172251 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,04479122 0,09164569 ! intermediate filament organization GO:0045109 12 8 0,000 0,04479122 0,091569 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,04479122 0,09149244 ! cellular extravasation GO:0045123 13 8 0,000 0,04479122 0,091416 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,04479122 0,09133969 ! response to antibiotic GO:0046677 11 8 0,000 0,04479122 0,09126351 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,04479122 0,09118746 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,04479122 0,09111154 ! DNA topological change GO:0006265 12 8 0,000 0,04479122 0,09103574 ! response to tropane GO:0014073 15 8 0,000 0,04479122 0,09096006 GO:0042220|response to cocaine, ! melanosome transport GO:0032402 13 8 0,000 0,04479122 0,09088451 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,04479122 0,09080909 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,04479122 0,09073379 ! mast cell activation GO:0045576 14 8 0,000 0,04479122 0,09065862 ! multicellular organismal aging GO:0010259 20 8 0,000 0,04479122 0,09058357 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 0,04479122 0,09050865 ! gas homeostasis GO:0033483 14 8 0,000 0,04479122 0,09043385 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,04479122 0,09035917 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,04479122 0,09028462 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,04479122 0,09021019 ! nucleosome disassembly GO:0006337 14 8 0,000 0,04479122 0,09013588 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,04479122 0,09006169 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 0,04479122 0,08998763 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,04479122 0,08991368 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,04479122 0,08983986 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,04479122 0,08976616 ! intracellular lipid transport GO:0032365 16 8 0,000 0,04479122 0,08969259 ! response to tumor cell GO:0002347 16 8 0,000 0,04479122 0,08961913 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,04479122 0,08954579 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,04479122 0,08947257 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 0,04479122 0,08939947 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 0,04479122 0,08932649 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,04479122 0,08925363 ! hormone catabolic process GO:0042447 17 8 0,000 0,04479122 0,08918089 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,04479122 0,08910827 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,04479122 0,08903576 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,04479122 0,08896338 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,04479122 0,08889111 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,04479122 0,08881896 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,04479122 0,08874692 ! adult feeding behavior GO:0008343 10 8 0,000 0,04479122 0,088675 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,04479122 0,0886032 ! ATP catabolic process GO:0006200 11 8 0,000 0,04479122 0,08853152 ! blastocyst growth GO:0001832 19 8 0,000 0,04479122 0,08845995 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,04479122 0,08838849 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,04479122 0,08831715 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,04479122 0,08824593 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,04479122 0,08817482 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,04479122 0,08810383 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,04479122 0,08803295 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,04479122 0,08796218 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,04479122 0,08789153 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,04479122 0,08782099 GO:0006043|glucosamine catabolic process, ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,04479122 0,08775056 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,04479122 0,08768025 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,04479122 0,08761005 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 0,04479122 0,08753996 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 0,04479122 0,08746999 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,04479122 0,08740012 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 0,04479122 0,08733037 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 0,04479122 0,08726073 ! establishment of organelle localization GO:0051656 122 59 1,000 0,04490298 0,08740875 ! regulation of neurotransmitter levels GO:0001505 113 60 1,000 0,04628085 0,0900192 ! lipid modification GO:0030258 112 60 1,000 0,04628085 0,08994759 ! regulation of cellular component size GO:0032535 125 61 1,000 0,04767414 0,09258181 ! cytokine-mediated signaling pathway GO:0019221 112 61 1,000 0,04767414 0,09250827 ! regulation of heart contraction GO:0008016 123 61 1,000 0,04767414 0,09243485 ! camera-type eye development GO:0043010 126 61 1,000 0,04767414 0,09236155 ! axon extension GO:0048675 16 9 0,000 0,05024787 0,09727063 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,05024787 0,09719362 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 0,05024787 0,09711673 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,05024787 0,09703995 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,05024787 0,0969633 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,05024787 0,09688677 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,05024787 0,09681036 ! reproductive behavior GO:0019098 22 9 0,000 0,05024787 0,09673408 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,05024787 0,09665791 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 0,05024787 0,09658186 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 0,05024787 0,09650593 ! UTP metabolic process GO:0046051 10 9 0,000 0,05024787 0,09643012 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,05024787 0,09635443 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,05024787 0,09627886 ! artery development GO:0060840 25 9 0,000 0,05024787 0,0962034 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,05024787 0,09612807 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,05024787 0,09605285 ! equilibrioception GO:0050957 20 9 0,000 0,05024787 0,09597775 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,05024787 0,09590277 ! chemosensory behavior GO:0007635 21 9 0,000 0,05024787 0,0958279 ! microtubule bundle formation GO:0001578 22 9 0,000 0,05024787 0,09575315 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,05024787 0,09567852 ! leukocyte degranulation GO:0043299 16 9 0,000 0,05024787 0,095604 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,05024787 0,0955296 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,05024787 0,09545532 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,05024787 0,09538115 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,05024787 0,0953071 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,05024787 0,09523316 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,05024787 0,09515933 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,05024787 0,09508562 ! protein targeting to ER GO:0045047 25 9 0,000 0,05024787 0,09501203 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,05024787 0,09493855 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 0,05024787 0,09486518 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,05024787 0,09479192 ! glycine catabolic process GO:0006546 15 9 0,000 0,05024787 0,09471878 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,05024787 0,09464575 ! endosome organization GO:0007032 20 9 0,000 0,05024787 0,09457284 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,05024787 0,09450003 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,05024787 0,09442734 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,05024787 0,09435476 ! mannose metabolic process GO:0006013 13 9 0,000 0,05024787 0,09428229 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,05024787 0,09420993 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,05024787 0,09413769 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 0,05024787 0,09406555 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,05024787 0,09399352 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,05024787 0,09392161 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,05024787 0,0938498 ! retinol metabolic process GO:0042572 20 9 0,000 0,05024787 0,09377811 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,05024787 0,09370652 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,05024787 0,09363504 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,05024787 0,09356367 ! macrophage differentiation GO:0030225 15 9 0,000 0,05024787 0,09349242 ! oligodendrocyte development GO:0014003 11 9 0,000 0,05024787 0,09342126 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,05024787 0,09335022 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,05024787 0,09327929 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,05024787 0,09320846 ! response to amine stimulus GO:0014075 13 9 0,000 0,05024787 0,09313774 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,05024787 0,09306713 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,05024787 0,09299662 ! erythrocyte development GO:0048821 17 9 0,000 0,05024787 0,09292622 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,05024787 0,09285593 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,05024787 0,09278575 ! renal water homeostasis GO:0003091 15 9 0,000 0,05024787 0,09271567 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,05024787 0,09264569 ! icosanoid secretion GO:0032309 15 9 0,000 0,05024787 0,09257582 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,05024787 0,09250606 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,05024787 0,0924364 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,05024787 0,09236685 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,05024787 0,0922974 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,05024787 0,09222806 ! sterol catabolic process GO:0016127 14 9 0,000 0,05024787 0,09215881 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,05024787 0,09208968 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,05024787 0,09202065 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,05024787 0,09195172 ! S phase GO:0051320 10 9 0,000 0,05024787 0,09188289 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,05024787 0,09181417 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,05024787 0,09174555 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,05024787 0,09167703 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,05024787 0,09160861 ! purine base metabolic process GO:0006144 25 9 0,000 0,05024787 0,0915403 ! pigment granule transport GO:0051904 17 9 0,000 0,05024787 0,09147209 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,05024787 0,09140398 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,05024787 0,09133597 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,05024787 0,09126806 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,05024787 0,09120025 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,05024787 0,09113255 ! mitochondrion localization GO:0051646 18 9 0,000 0,05024787 0,09106494 ! regulation of protein complex assembly GO:0043254 132 63 1,000 0,05050609 0,09146506 ! integrin-mediated signaling pathway GO:0007229 160 64 1,000 0,05194431 0,09399997 ! regulation of lipid metabolic process GO:0019216 132 66 1,000 0,05486422 0,09921043 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,0556735 0,10059937 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,0556735 0,10052502 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,0556735 0,10045078 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,0556735 0,10037664 ! associative learning GO:0008306 21 10 0,000 0,0556735 0,10030262 ! phosphate transport GO:0006817 24 10 0,000 0,0556735 0,1002287 ! cell volume homeostasis GO:0006884 17 10 0,000 0,0556735 0,1001549 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,0556735 0,1000812 ! CTP metabolic process GO:0046036 11 10 0,000 0,0556735 0,10000761 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,0556735 0,09993413 ! GTP metabolic process GO:0046039 11 10 0,000 0,0556735 0,09986076 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,0556735 0,09978749 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,0556735 0,09971433 ! social behavior GO:0035176 29 10 0,000 0,0556735 0,09964128 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,0556735 0,09956834 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,0556735 0,0994955 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,0556735 0,09942277 ! androgen metabolic process GO:0008209 17 10 0,000 0,0556735 0,09935015 ! phospholipid efflux GO:0033700 19 10 0,000 0,0556735 0,09927763 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,0556735 0,09920522 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,0556735 0,09913291 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,0556735 0,09906071 ! pathogenesis GO:0009405 17 10 0,000 0,0556735 0,09898861 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,0556735 0,09891662 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 0,0556735 0,09884473 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,0556735 0,09877295 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,0556735 0,09870127 ! endoderm development GO:0007492 18 10 0,000 0,0556735 0,0986297 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,0556735 0,09855822 ! arginine catabolic process GO:0006527 17 10 0,000 0,0556735 0,09848686 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,0556735 0,09841559 ! proline metabolic process GO:0006560 13 10 0,000 0,0556735 0,09834443 ! phosphagen metabolic process GO:0006599 17 10 0,000 0,0556735 0,09827337 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,0556735 0,09820242 ! V(D)J recombination GO:0033151 34 10 0,000 0,0556735 0,09813157 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,0556735 0,09806081 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,0556735 0,09799017 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,0556735 0,09791962 ! B cell proliferation GO:0042100 19 10 0,000 0,0556735 0,09784917 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,0556735 0,09777883 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,0556735 0,09770858 ! multicellular organism growth GO:0035264 19 10 0,000 0,0556735 0,09763844 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,0556735 0,0975684 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,0556735 0,09749846 ! ruffle organization GO:0031529 17 10 0,000 0,0556735 0,09742862 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,0556735 0,09735888 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,0556735 0,09728923 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,0556735 0,09721969 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,0556735 0,09715025 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,0556735 0,09708091 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,0556735 0,09701166 GO:0030204|chondroitin sulfate metabolic process, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 0,000 0,0556735 0,09694252 ! copper ion homeostasis GO:0055070 13 10 0,000 0,0556735 0,09687347 ! brain morphogenesis GO:0048854 23 10 0,000 0,0556735 0,09680452 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,0556735 0,09673567 ! segment specification GO:0007379 15 10 0,000 0,0556735 0,09666692 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,0556735 0,09659826 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 0,000 0,0556735 0,0965297 ! blastoderm segmentation GO:0007350 19 10 0,000 0,0556735 0,09646124 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,0556735 0,09639288 ! response to dsRNA GO:0043331 23 10 0,000 0,0556735 0,09632461 ! DNA ligation GO:0006266 18 10 0,000 0,0556735 0,09625644 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,0556735 0,09618837 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,0556735 0,09612039 ! melanosome localization GO:0032400 16 10 0,000 0,0556735 0,09605251 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,0556735 0,09598472 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,0556735 0,09591703 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,0556735 0,09584944 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,0556735 0,09578194 ! induction of an organ GO:0001759 17 10 0,000 0,0556735 0,09571453 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,0556735 0,09564722 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,0556735 0,09558001 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,0556735 0,09551289 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,0556735 0,09544586 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,0556735 0,09537893 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,0556735 0,09531209 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,0556735 0,09524534 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,0556735 0,09517869 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,0556735 0,09511213 ! midbrain development GO:0030901 14 10 0,000 0,0556735 0,09504567 ! musculoskeletal movement GO:0050881 16 10 0,000 0,0556735 0,09497929 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,0556735 0,09491301 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,0556735 0,09484683 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,0556735 0,09478073 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,0556735 0,09471473 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,0556735 0,09464882 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,0556735 0,094583 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,0556735 0,09451727 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,0556735 0,09445163 ! detection of calcium ion GO:0005513 24 10 0,000 0,0556735 0,09438609 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,0556735 0,09432063 ! blastocyst formation GO:0001825 18 10 0,000 0,0556735 0,09425527 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,0556735 0,09418999 ! cerebellar cortex development GO:0021695 16 10 0,000 0,0556735 0,09412481 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,0556735 0,09405972 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,0556735 0,09399471 ! response to nicotine GO:0035094 20 10 0,000 0,0556735 0,0939298 ! chromosome segregation GO:0007059 127 67 1,000 0,05634547 0,09499792 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 1,000 0,05634547 0,09493241 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 1,000 0,05784065 0,09738436 ! extracellular matrix organization GO:0030198 146 68 1,000 0,05784065 0,09731729 ! detection of external stimulus GO:0009581 102 68 1,000 0,05784065 0,09725031 ! positive regulation of T cell activation GO:0050870 124 68 1,000 0,05784065 0,09718343 ! regulation of lipase activity GO:0060191 137 68 1,000 0,05784065 0,09711664 ! adaptive immune response GO:0002250 126 68 1,000 0,05784065 0,09704994 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! cell projection assembly GO:0030031 138 68 1,000 0,05784065 0,09698333 ! germ cell development GO:0007281 133 70 1,000 0,06087196 0,10199601 ! activation of immune response GO:0002253 120 70 1,000 0,06087196 0,1019261 ! negative regulation of muscle development GO:0048635 27 11 0,000 0,06106828 0,1021848 ! respiratory burst GO:0045730 17 11 0,000 0,06106828 0,10211486 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,06106828 0,10204501 ! neuron fate specification GO:0048665 18 11 0,000 0,06106828 0,10197526 ! telencephalon cell migration GO:0022029 23 11 0,000 0,06106828 0,10190561 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,06106828 0,10183605 ! thyroid gland development GO:0030878 26 11 0,000 0,06106828 0,10176658 ! synapsis GO:0007129 14 11 0,000 0,06106828 0,10169721 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,06106828 0,10162794 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,06106828 0,10155875 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 0,000 0,06106828 0,10148967 ! response to pain GO:0048265 27 11 0,000 0,06106828 0,10142067 ! keratinocyte proliferation GO:0043616 19 11 0,000 0,06106828 0,10135177 ! bone resorption GO:0045453 16 11 0,000 0,06106828 0,10128297 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,06106828 0,10121425 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,06106828 0,10114563 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,06106828 0,10107711 ! melanocyte differentiation GO:0030318 20 11 0,000 0,06106828 0,10100867 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,06106828 0,10094033 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,06106828 0,10087208 ! L-serine metabolic process GO:0006563 21 11 0,000 0,06106828 0,10080393 ! regulation of intracellular pH GO:0051453 21 11 0,000 0,06106828 0,10073586 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,06106828 0,10066789 ! UV protection GO:0009650 20 11 0,000 0,06106828 0,10060001 ! adult heart development GO:0007512 16 11 0,000 0,06106828 0,10053222 ! chondrocyte differentiation GO:0002062 27 11 0,000 0,06106828 0,10046452 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,06106828 0,10039691 ! macroautophagy GO:0016236 19 11 0,000 0,06106828 0,10032939 ! temperature homeostasis GO:0001659 18 11 0,000 0,06106828 0,10026197 ! behavioral fear response GO:0001662 27 11 0,000 0,06106828 0,10019463 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,06106828 0,10012739 ! negative regulation of ossification GO:0030279 27 11 0,000 0,06106828 0,10006023 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,06106828 0,09999317 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,06106828 0,09992619 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 0,06106828 0,09985931 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,06106828 0,09979251 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,06106828 0,09972581 ! regulation of organ growth GO:0046620 14 11 0,000 0,06106828 0,09965919 ! pigment granule localization GO:0051875 20 11 0,000 0,06106828 0,09959266 ! vasoconstriction GO:0042310 20 11 0,000 0,06106828 0,09952622 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,06106828 0,09945987 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,06106828 0,09939361 ! embryonic axis specification GO:0000578 19 11 0,000 0,06106828 0,09932744 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,06106828 0,09926135 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,06106828 0,09919535 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,06106828 0,09912944 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,06106828 0,09906362 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,06106828 0,09899788 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,06106828 0,09893223 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,06106828 0,09886667 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,06106828 0,0988012 ! prophase GO:0051324 17 11 0,000 0,06106828 0,09873581 ! nucleosome positioning GO:0016584 15 11 0,000 0,06106828 0,09867051 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,06106828 0,09860529 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,06106828 0,09854016 ! acid secretion GO:0046717 20 11 0,000 0,06106828 0,09847512 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,06106828 0,09841016 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,06106828 0,09834529 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,06106828 0,09828051 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,06106828 0,09821581 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,06106828 0,09815119 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 0,06106828 0,09808666 ! cholesterol efflux GO:0033344 21 11 0,000 0,06106828 0,09802221 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,06106828 0,09795785 ! oocyte development GO:0048599 20 11 0,000 0,06106828 0,09789358 ! negative regulation of glucose import GO:0046325 18 11 0,000 0,06106828 0,09782938 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 26 11 0,000 0,06106828 0,09776527 ! embryonic gut development GO:0048566 19 11 0,000 0,06106828 0,09770125 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,06106828 0,09763731 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,06106828 0,09757345 ! activation of innate immune response GO:0002218 16 11 0,000 0,06106828 0,09750968 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,06106828 0,09744599 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,06106828 0,09738238 ! lysogeny GO:0030069 22 11 0,000 0,06106828 0,09731886 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,06106828 0,09725542 ! sequestering of metal ion GO:0051238 15 11 0,000 0,06106828 0,09719206 ! nucleus localization GO:0051647 22 11 0,000 0,06106828 0,09712878 ! cAMP-mediated signaling GO:0019933 124 71 1,000 0,06240768 0,09919451 ! regulation of immune effector process GO:0002697 156 73 1,000 0,06551826 0,10407095 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,0664324 0,10545442 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,0664324 0,10538594 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,0664324 0,10531755 ! mating GO:0007618 17 12 0,000 0,0664324 0,10524925 ! regulation of cell projection assembly GO:0060491 33 12 0,000 0,0664324 0,10518104 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,0664324 0,10511292 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,0664324 0,10504488 ! ventral spinal cord development GO:0021517 25 12 0,000 0,0664324 0,10497694 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,0664324 0,10490908 ! drug transport GO:0015893 16 12 0,000 0,0664324 0,10484131 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,0664324 0,10477362 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,0664324 0,10470603 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,0664324 0,10463852 ! polyamine metabolic process GO:0006595 18 12 0,000 0,0664324 0,1045711 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,0664324 0,10450376 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,0664324 0,10443652 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,0664324 0,10436935 ! lipid digestion GO:0044241 21 12 0,000 0,0664324 0,10430228 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,0664324 0,10423529 ! entry into host cell GO:0030260 34 12 0,000 0,0664324 0,10416839 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,0664324 0,10410157 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,0664324 0,10403484 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,0664324 0,10396819 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,0664324 0,10390163 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,0664324 0,10383515 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,0664324 0,10376876 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,0664324 0,10370246 ! snRNA metabolic process GO:0016073 30 12 0,000 0,0664324 0,10363624 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,0664324 0,1035701 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,0664324 0,10350405 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,0664324 0,10343808 ! fucose catabolic process GO:0019317 25 12 0,000 0,0664324 0,10337219 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,0664324 0,10330639 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,0664324 0,10324068 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 0,0664324 0,10317504 ! zymogen activation GO:0031638 18 12 0,000 0,0664324 0,10310949 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,0664324 0,10304403 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,0664324 0,10297865 ! oocyte differentiation GO:0009994 21 12 0,000 0,0664324 0,10291334 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,0664324 0,10284813 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,0664324 0,10278299 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,0664324 0,10271794 ! defense response to fungus GO:0050832 15 12 0,000 0,0664324 0,10265297 ! developmental induction GO:0031128 22 12 0,000 0,0664324 0,10258808 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 21 12 0,000 0,0664324 0,10252328 ! lamellipodium assembly GO:0030032 24 12 0,000 0,0664324 0,10245855 ! response to cold GO:0009409 17 12 0,000 0,0664324 0,10239391 ! establishment of cell polarity GO:0030010 21 12 0,000 0,0664324 0,10232935 ! organelle localization GO:0051640 155 74 1,000 0,06709273 0,10328138 ! phosphoinositide-mediated signaling GO:0048015 141 75 1,000 0,06867972 0,10565779 ! regulation of actin cytoskeleton organization GO:0032956 167 76 1,000 0,07027905 0,10805017 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 1,000 0,07027905 0,10798221 ! lymphocyte differentiation GO:0030098 193 76 1,000 0,07027905 0,10791434 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,07176602 0,11012838 ! cGMP metabolic process GO:0046068 18 13 0,000 0,07176602 0,11005925 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,07176602 0,1099902 ! regulation of chemokine production GO:0032642 18 13 0,000 0,07176602 0,10992124 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,07176602 0,10985237 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,07176602 0,10978358 ! peroxisomal transport GO:0043574 28 13 0,000 0,07176602 0,10971488 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,07176602 0,10964627 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,07176602 0,10957774 ! organelle fusion GO:0048284 36 13 0,000 0,07176602 0,10950929 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,07176602 0,10944094 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,07176602 0,10937266 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,07176602 0,10930448 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,07176602 0,10923637 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,07176602 0,10916836 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,07176602 0,10910042 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,07176602 0,10903258 ! methionine metabolic process GO:0006555 31 13 0,000 0,07176602 0,10896481 ! plasma membrane organization GO:0007009 27 13 0,000 0,07176602 0,10889713 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,07176602 0,10882954 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,07176602 0,10876202 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,07176602 0,10869459 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,07176602 0,10862725 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! response to X-ray GO:0010165 28 13 0,000 0,07176602 0,10855999 ! cytokine metabolic process GO:0042107 24 13 0,000 0,07176602 0,10849281 ! cellular carbohydrate catabolic process GO:0044275 17 13 0,000 0,07176602 0,10842571 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,07176602 0,1083587 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 0,07176602 0,10829177 ! L-glutamate transport GO:0015813 30 13 0,000 0,07176602 0,10822493 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,07176602 0,10815816 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,07176602 0,10809148 ! protein homotetramerization GO:0051289 24 13 0,000 0,07176602 0,10802488 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,07176602 0,10795836 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,07176602 0,10789193 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,07176602 0,10782557 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,07176602 0,1077593 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,07176602 0,10769311 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,07176602 0,107627 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,07176602 0,10756097 ! histone methylation GO:0016571 29 13 0,000 0,07176602 0,10749502 ! chromatin silencing GO:0006342 29 13 0,000 0,07176602 0,10742916 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,07176602 0,10736337 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 0,07176602 0,10729766 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,07176602 0,10723204 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,07176602 0,10716649 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,07176602 0,10710103 ! spleen development GO:0048536 24 13 0,000 0,07176602 0,10703564 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,07176602 0,10697034 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,07176602 0,10690511 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,07176602 0,10683996 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,07176602 0,1067749 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,07176602 0,10670991 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,07176602 0,106645 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,07176602 0,10658017 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,07176602 0,10651542 ! insulin secretion GO:0030073 24 13 0,000 0,07176602 0,10645075 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,07176602 0,10638615 ! acrosome reaction GO:0007340 19 13 0,000 0,07176602 0,10632164 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,07176602 0,1062572 ! neurotransmitter transport GO:0006836 142 77 1,000 0,07189051 0,10637705 ! phosphoinositide metabolic process GO:0030384 146 77 1,000 0,07189051 0,10631266 ! cytosolic calcium ion homeostasis GO:0051480 149 77 1,000 0,07189051 0,10624835 ! regulation of actin filament-based process GO:0032970 170 79 1,000 0,0751491 0,11099713 ! protein oligomerization GO:0051259 149 79 1,000 0,0751491 0,11093006 ! regulation of synaptic transmission GO:0050804 159 79 1,000 0,0751491 0,11086308 ! activation of protein kinase activity GO:0032147 170 80 1,000 0,07679586 0,11322407 ! negative regulation of organelle organization GO:0010639 181 80 1,000 0,07679586 0,11315578 ! rRNA transcription GO:0009303 28 14 0,000 0,07706932 0,11349026 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,07706932 0,11342189 GO:0046579|positive regulation of Ras protein signal transduction, ! water transport GO:0006833 21 14 0,000 0,07706932 0,11335361 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,07706932 0,1132854 ! non-recombinational repair GO:0000726 29 14 0,000 0,07706932 0,11321728 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,07706932 0,11314924 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,07706932 0,11308128 ! RNA polyadenylation GO:0043631 32 14 0,000 0,07706932 0,11301341 ! lipid localization GO:0010876 32 14 0,000 0,07706932 0,11294561 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 0,07706932 0,1128779 ! regulated secretory pathway GO:0045055 24 14 0,000 0,07706932 0,11281027 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,07706932 0,11274272 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,07706932 0,11267525 ! arginine metabolic process GO:0006525 21 14 0,000 0,07706932 0,11260786 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,07706932 0,11254055 ! regulation of heart rate GO:0002027 25 14 0,000 0,07706932 0,11247332 ! fear response GO:0042596 34 14 0,000 0,07706932 0,11240617 ! organic alcohol transport GO:0015850 29 14 0,000 0,07706932 0,1123391 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,07706932 0,11227212 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 0,000 0,07706932 0,11220521 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,07706932 0,11213838 ! neutral amino acid transport GO:0015804 28 14 0,000 0,07706932 0,11207163 ! bone mineralization GO:0030282 18 14 0,000 0,07706932 0,11200496 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,07706932 0,11193837 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,07706932 0,11187186 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,07706932 0,11180543 ! regulation of cellular pH GO:0030641 27 14 0,000 0,07706932 0,11173907 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,07706932 0,1116728 ! ribosome assembly GO:0042255 18 14 0,000 0,07706932 0,1116066 ! cerebellum development GO:0021549 23 14 0,000 0,07706932 0,11154049 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,07706932 0,11147445 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,07706932 0,11140848 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,07706932 0,1113426 ! response to gamma radiation GO:0010332 30 14 0,000 0,07706932 0,1112768 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,07706932 0,11121107 ! NADP metabolic process GO:0006739 24 14 0,000 0,07706932 0,11114542 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,07706932 0,11107985 ! oxygen transport GO:0015671 22 14 0,000 0,07706932 0,11101435 ! male genitalia development GO:0030539 26 14 0,000 0,07706932 0,11094893 ! regulation of axon extension GO:0030516 43 14 0,000 0,07706932 0,11088359 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,07706932 0,11081833 ! muscle cell differentiation GO:0042692 178 81 1,000 0,078454 0,11274302 ! positive regulation of phosphorylation GO:0042327 149 81 1,000 0,078454 0,11267674 ! regulation of adenylate cyclase activity GO:0045761 165 83 1,000 0,08180375 0,11741867 ! exocytosis GO:0006887 153 83 1,000 0,08180375 0,11734972 ! response to drug GO:0042493 149 83 1,000 0,08180375 0,11728085 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 1,000 0,08180375 0,11721206 GO:0045937|positive regulation of phosphate metabolic process, ! lactation GO:0007595 30 15 0,000 0,08234246 0,11791479 ! reproductive cellular process GO:0048610 22 15 0,000 0,08234246 0,11784572 ! tRNA modification GO:0006400 24 15 0,000 0,08234246 0,11777672 ! superoxide anion generation GO:0042554 22 15 0,000 0,08234246 0,1177078 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,08234246 0,11763897 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,08234246 0,11757022 ! copper ion transport GO:0006825 22 15 0,000 0,08234246 0,11750154 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,08234246 0,11743295 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,08234246 0,11736443 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,08234246 0,117296 ! sulfate transport GO:0008272 27 15 0,000 0,08234246 0,11722764 ! response to cAMP GO:0051591 25 15 0,000 0,08234246 0,11715937 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,08234246 0,11709117 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,08234246 0,11702306 ! regulation of mRNA processing GO:0050684 26 15 0,000 0,08234246 0,11695502 ! response to hexose stimulus GO:0009746 25 15 0,000 0,08234246 0,11688706 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,08234246 0,11681919 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,08234246 0,11675139 ! vesicle coating GO:0006901 38 15 0,000 0,08234246 0,11668366 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 0,08234246 0,11661602 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 0,000 0,08234246 0,11654846 ! regulation of exocytosis GO:0017157 26 15 0,000 0,08234246 0,11648097 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,08234246 0,11641356 ! G1/S transition checkpoint GO:0031575 37 15 0,000 0,08234246 0,11634623 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,08234246 0,11627898 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,08234246 0,11621181 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,08234246 0,11614471 ! regulation of vasodilation GO:0042312 27 15 0,000 0,08234246 0,11607769 ! histone deacetylation GO:0016575 24 15 0,000 0,08234246 0,11601075 ! water homeostasis GO:0030104 28 15 0,000 0,08234246 0,11594388 ! cofactor transport GO:0051181 30 15 0,000 0,08234246 0,1158771 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,08234246 0,11581038 ! muscle maintenance GO:0046716 26 15 0,000 0,08234246 0,11574375 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,08234246 0,11567719 ! intestinal absorption GO:0050892 31 15 0,000 0,08234246 0,11561071 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,08234246 0,11554431 ! heme biosynthetic process GO:0006783 33 15 0,000 0,08234246 0,11547798 ! cell killing GO:0001906 32 15 0,000 0,08234246 0,11541173 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,08234246 0,11534555 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,08234246 0,11527945 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,08234246 0,11521342 ! actin filament polymerization GO:0030041 27 15 0,000 0,08234246 0,11514747 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,08234246 0,1150816 ! T cell activation GO:0042110 189 84 1,000 0,083495 0,11662566 ! response to nutrient GO:0007584 135 84 1,000 0,083495 0,11655901 ! negative regulation of transport GO:0051051 164 85 1,000 0,08519691 0,11886696 ! regulation of cyclase activity GO:0031279 168 85 1,000 0,08519691 0,11879912 ! regulation of transmission of nerve impulse GO:0051969 167 85 1,000 0,08519691 0,11873135 ! regulation of cAMP biosynthetic process GO:0030817 173 86 1,000 0,08690933 0,12104874 ! regulation of lyase activity GO:0051339 169 86 1,000 0,08690933 0,12097976 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,08758563 0,12185176 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,08758563 0,12178241 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,08758563 0,12171314 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,08758563 0,12164394 ! bone remodeling GO:0046849 28 16 0,000 0,08758563 0,12157483 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 0,000 0,08758563 0,12150579 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,08758563 0,12143683 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,08758563 0,12136795 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,08758563 0,12129915 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,08758563 0,12123042 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,08758563 0,12116178 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,08758563 0,12109321 ! startle response GO:0001964 28 16 0,000 0,08758563 0,12102471 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,08758563 0,1209563 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,08758563 0,12088796 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,08758563 0,1208197 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,08758563 0,12075152 ! protein polyubiquitination GO:0000209 41 16 0,000 0,08758563 0,12068342 ! glutamate metabolic process GO:0006536 25 16 0,000 0,08758563 0,12061539 ! pituitary gland development GO:0021983 30 16 0,000 0,08758563 0,12054743 ! response to osmotic stress GO:0006970 27 16 0,000 0,08758563 0,12047956 ! lysosomal transport GO:0007041 31 16 0,000 0,08758563 0,12041176 ! fructose metabolic process GO:0006000 25 16 0,000 0,08758563 0,12034404 ! L-amino acid transport GO:0015807 33 16 0,000 0,08758563 0,12027639 ! stem cell development GO:0048864 46 16 0,000 0,08758563 0,12020882 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,08758563 0,12014132 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 36 16 0,000 0,08758563 0,1200739 ! axon cargo transport GO:0008088 46 16 0,000 0,08758563 0,12000656 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,08758563 0,11993929 ! DNA replication initiation GO:0006270 28 16 0,000 0,08758563 0,1198721 ! mRNA splice site selection GO:0006376 44 16 0,000 0,08758563 0,11980498 ! tissue regeneration GO:0042246 27 16 0,000 0,08758563 0,11973794 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,08758563 0,11967097 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,08758563 0,11960408 ! biomineral formation GO:0031214 22 16 0,000 0,08758563 0,11953726 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,08758563 0,11947052 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,08758563 0,11940385 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,08758563 0,11933725 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,08758563 0,11927073 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,08758563 0,11920429 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,08758563 0,11913792 ! peptide hormone processing GO:0016486 27 16 0,000 0,08758563 0,11907162 ! regulation of protein transport GO:0051223 165 87 1,000 0,08863206 0,12042722 GO:0070201|regulation of establishment of protein localization, ! amine biosynthetic process GO:0009309 146 88 1,000 0,09036496 0,1227135 ! regulation of cAMP metabolic process GO:0030814 182 89 1,000 0,09210783 0,12501079 ! tube morphogenesis GO:0035239 194 89 1,000 0,09210783 0,12494138 ! regulation of neurological system process GO:0031644 175 89 1,000 0,09210783 0,12487205 ! metencephalon development GO:0022037 32 17 0,000 0,09279899 0,12573928 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,09279899 0,12566958 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,09279899 0,12559996 ! filopodium assembly GO:0046847 42 17 0,000 0,09279899 0,12553041 ! endothelial cell migration GO:0043542 31 17 0,000 0,09279899 0,12546094 ! gene silencing by RNA GO:0031047 38 17 0,000 0,09279899 0,12539155 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,09279899 0,12532224 ! glial cell development GO:0021782 28 17 0,000 0,09279899 0,125253 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,09279899 0,12518383 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,09279899 0,12511475 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 0,000 0,09279899 0,12504574 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,09279899 0,12497681 ! myoblast differentiation GO:0045445 50 17 0,000 0,09279899 0,12490795 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,09279899 0,12483917 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,09279899 0,12477046 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,09279899 0,12470183 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,09279899 0,12463327 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,09279899 0,12456479 ! negative regulation of microtubule depolymerization GO:0007026 50 17 0,000 0,09279899 0,12449639 GO:0031114|regulation of microtubule depolymerization, ! NAD metabolic process GO:0019674 33 17 0,000 0,09279899 0,12442806 ! membrane budding GO:0006900 42 17 0,000 0,09279899 0,1243598 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,09279899 0,12429163 ! regulation of protein binding GO:0043393 33 17 0,000 0,09279899 0,12422352 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,09279899 0,12415549 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,09279899 0,12408753 ! genitalia development GO:0048806 32 17 0,000 0,09279899 0,12401965 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,09279899 0,12395184 ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,09279899 0,12388411 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,09279899 0,12381645 ! steroid catabolic process GO:0006706 34 17 0,000 0,09279899 0,12374887 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,09279899 0,12368136 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,09279899 0,12361392 ! gas transport GO:0015669 26 17 0,000 0,09279899 0,12354655 ! organic cation transport GO:0015695 32 17 0,000 0,09279899 0,12347926 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,09279899 0,12341204 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 1,000 0,09562285 0,12709827 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,0979827 0,13016408 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,0979827 0,13009334 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,0979827 0,13002267 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,0979827 0,12995208 ! adult walking behavior GO:0007628 36 18 0,000 0,0979827 0,12988157 ! patterning of blood vessels GO:0001569 43 18 0,000 0,0979827 0,12981114 ! heart looping GO:0001947 34 18 0,000 0,0979827 0,12974078 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,0979827 0,1296705 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,0979827 0,12960029 ! centrosome cycle GO:0007098 26 18 0,000 0,0979827 0,12953016 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,0979827 0,12946011 ! glycine metabolic process GO:0006544 30 18 0,000 0,0979827 0,12939013 ! glutamine metabolic process GO:0006541 29 18 0,000 0,0979827 0,12932023 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,0979827 0,1292504 ! DNA integration GO:0015074 32 18 0,000 0,0979827 0,12918065 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,0979827 0,12911097 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,0979827 0,12904137 ! neural crest cell migration GO:0001755 41 18 0,000 0,0979827 0,12897184 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,0979827 0,12890239 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,0979827 0,12883301 GO:0046466|membrane lipid catabolic process, ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,0979827 0,12876371 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,0979827 0,12869448 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,0979827 0,12862533 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,0979827 0,12855625 ! detection of bacterium GO:0016045 22 18 0,000 0,0979827 0,12848725 ! microspike assembly GO:0030035 46 18 0,000 0,0979827 0,12841831 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 0,000 0,0979827 0,12834946 ! carbohydrate biosynthetic process GO:0016051 158 94 1,000 0,10096606 0,13218653 ! regulation of membrane potential GO:0042391 179 94 1,000 0,10096606 0,13211573 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 1,000 0,10276532 0,13439812 ! negative regulation of multicellular organismal process GO:0051241 174 95 1,000 0,10276532 0,13432621 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,10313694 0,13473986 ! positive regulation of translation GO:0045727 31 19 0,000 0,10313694 0,13466785 ! negative regulation of defense response GO:0031348 27 19 0,000 0,10313694 0,13459591 ! G1 phase of mitotic cell cycle GO:0000080 39 19 0,000 0,10313694 0,13452405 ! neuron maturation GO:0042551 46 19 0,000 0,10313694 0,13445227 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,10313694 0,13438056 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 0,10313694 0,13430893 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,10313694 0,13423737 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,10313694 0,13416589 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,10313694 0,13409449 ! inositol metabolic process GO:0006020 33 19 0,000 0,10313694 0,13402316 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,10313694 0,13395191 ! memory GO:0007613 34 19 0,000 0,10313694 0,13388074 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,10313694 0,13380964 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,10313694 0,13373861 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,10313694 0,13366766 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,10313694 0,13359679 ! cerebral cortex development GO:0021987 40 19 0,000 0,10313694 0,13352599 ! pigmentation during development GO:0048066 42 19 0,000 0,10313694 0,13345527 ! heme metabolic process GO:0042168 40 19 0,000 0,10313694 0,13338462 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,10313694 0,13331404 ! response to fungus GO:0009620 26 19 0,000 0,10313694 0,13324355 ! peptide cross-linking GO:0018149 39 19 0,000 0,10313694 0,13317312 ! protein export from nucleus GO:0006611 40 19 0,000 0,10313694 0,13310277 ! heart process GO:0003015 32 19 0,000 0,10313694 0,13303249 GO:0060047|heart contraction, ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,10313694 0,13296229 ! visual learning GO:0008542 38 19 0,000 0,10313694 0,13289216 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,10313694 0,13282211 ! vitamin transport GO:0051180 31 19 0,000 0,10313694 0,13275213 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,10313694 0,13268222 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,10313694 0,13261239 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,10313694 0,13254263 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,10313694 0,13247295 ! cilium assembly GO:0042384 38 19 0,000 0,10313694 0,13240333 ! peptide hormone secretion GO:0030072 32 19 0,000 0,10313694 0,13233379 ! sex differentiation GO:0007548 171 96 1,000 0,10457342 0,13410649 ! biogenic amine metabolic process GO:0006576 162 97 1,000 0,10639019 0,13636476 ! transcription initiation GO:0006352 171 97 1,000 0,10639019 0,13629325 ! regulation of protein localization GO:0032880 188 97 1,000 0,10639019 0,13622182 ! leukocyte differentiation GO:0002521 232 98 1,000 0,10821547 0,13848633 ! regulation of nucleotide metabolic process GO:0006140 197 98 1,000 0,10821547 0,13841382 ! protein secretion GO:0009306 45 20 0,000 0,10826187 0,13840071 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,10826187 0,13832832 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,10826187 0,13825601 ! skin development GO:0043588 42 20 0,000 0,10826187 0,13818378 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,10826187 0,13811162 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,10826187 0,13803954 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,10826187 0,13796753 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,10826187 0,1378956 ! forelimb morphogenesis GO:0035136 35 20 0,000 0,10826187 0,13782374 ! bile acid metabolic process GO:0008206 34 20 0,000 0,10826187 0,13775195 ! retinoid metabolic process GO:0001523 34 20 0,000 0,10826187 0,13768025 GO:0016101|diterpenoid metabolic process, ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,10826187 0,13760861 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,10826187 0,13753705 GO:0032392|DNA geometric change, ! cellular response to unfolded protein GO:0034620 35 20 0,000 0,10826187 0,13746557 GO:0030968|endoplasmic reticulum unfolded protein response, ! body fluid secretion GO:0007589 33 20 0,000 0,10826187 0,13739416 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,10826187 0,13732282 ! peptide secretion GO:0002790 38 20 0,000 0,10826187 0,13725156 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,10826187 0,13718037 ! regulation of fatty acid metabolic process GO:0019217 45 20 0,000 0,10826187 0,13710926 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,10826187 0,13703821 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,10826187 0,13696725 GO:0006626|protein targeting to mitochondrion, ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,10826187 0,13689635 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,10826187 0,13682553 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,10826187 0,13675478 ! regulation of glucose import GO:0046324 30 20 0,000 0,10826187 0,13668411 GO:0010827|regulation of glucose transport, ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,10826187 0,13661351 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,10826187 0,13654298 ! negative regulation of translation GO:0017148 32 20 0,000 0,10826187 0,13647252 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,10826187 0,13640214 ! hormone metabolic process GO:0042445 171 100 1,000 0,11189097 0,14090187 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,11335766 0,14267531 ! hormone secretion GO:0046879 39 21 0,000 0,11335766 0,14260184 ! cAMP metabolic process GO:0046058 41 21 0,000 0,11335766 0,14252844 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,11335766 0,14245513 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,11335766 0,14238189 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,11335766 0,14230872 ! ovarian follicle development GO:0001541 39 21 0,000 0,11335766 0,14223563 ! smooth muscle contraction GO:0006939 48 21 0,000 0,11335766 0,14216261 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,11335766 0,14208967 ! plasma membrane fusion GO:0045026 33 21 0,000 0,11335766 0,1420168 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,11335766 0,14194401 GO:0006692|prostanoid metabolic process, ! regulation of vasoconstriction GO:0019229 40 21 0,000 0,11335766 0,14187129 ! sensory perception of pain GO:0019233 33 21 0,000 0,11335766 0,14179865 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,11335766 0,14172608 ! diencephalon development GO:0021536 36 21 0,000 0,11335766 0,14165359 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,11335766 0,14158117 ! negative regulation of intracellular transport GO:0032387 44 21 0,000 0,11335766 0,14150882 ! positive regulation of inflammatory response GO:0050729 41 21 0,000 0,11335766 0,14143655 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,11335766 0,14136435 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 0,11335766 0,14129223 ! collagen catabolic process GO:0030574 29 21 0,000 0,11335766 0,14122018 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,11335766 0,1411482 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,11335766 0,1410763 ! sperm-egg recognition GO:0035036 23 21 0,000 0,11335766 0,14100446 ! actin filament-based movement GO:0030048 47 21 0,000 0,11335766 0,14093271 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 0,000 0,11335766 0,14086102 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,11842447 0,14708235 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,11842447 0,14700762 ! microtubule-based transport GO:0010970 59 22 0,000 0,11842447 0,14693296 ! hindlimb morphogenesis GO:0035137 47 22 0,000 0,11842447 0,14685837 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,11842447 0,14678386 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 0,000 0,11842447 0,14670943 ! vacuolar transport GO:0007034 41 22 0,000 0,11842447 0,14663507 ! fucose metabolic process GO:0006004 44 22 0,000 0,11842447 0,14656079 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,11842447 0,14648658 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,11842447 0,14641245 ! ureteric bud development GO:0001657 50 22 0,000 0,11842447 0,14633839 ! cell aging GO:0007569 48 22 0,000 0,11842447 0,1462644 ! stem cell differentiation GO:0048863 57 22 0,000 0,11842447 0,1461905 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,11842447 0,14611666 ! cytolysis GO:0019835 27 22 0,000 0,11842447 0,1460429 ! renal system process GO:0003014 42 22 0,000 0,11842447 0,14596922 ! vasodilation GO:0042311 40 22 0,000 0,11842447 0,14589561 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,11842447 0,14582207 ! detection of chemical stimulus GO:0009593 42 22 0,000 0,11842447 0,14574861 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,11842447 0,14567522 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,11842447 0,14560191 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,11842447 0,14552867 ! sarcomere organization GO:0045214 32 22 0,000 0,11842447 0,1454555 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,11842447 0,14538241 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,11842447 0,14530939 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,11842447 0,14523644 ! gut development GO:0048565 44 22 0,000 0,11842447 0,14516357 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,11842447 0,14509077 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,12346247 0,15118738 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,12346247 0,15111164 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,12346247 0,15103597 ! gluconeogenesis GO:0006094 38 23 0,000 0,12346247 0,15096037 ! glycerol metabolic process GO:0006071 40 23 0,000 0,12346247 0,15088486 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,12346247 0,15080941 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,12346247 0,15073405 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,12346247 0,15065875 ! regeneration GO:0031099 42 23 0,000 0,12346247 0,15058354 ! axis specification GO:0009798 43 23 0,000 0,12346247 0,1505084 ! visual behavior GO:0007632 46 23 0,000 0,12346247 0,15043333 ! response to ethanol GO:0045471 47 23 0,000 0,12346247 0,15035834 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,12346247 0,15028342 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,12346247 0,15020858 ! peroxisome organization GO:0007031 43 23 0,000 0,12346247 0,15013381 ! lysosome organization GO:0007040 47 23 0,000 0,12346247 0,15005912 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 0,12346247 0,1499845 ! vesicle targeting GO:0006903 49 23 0,000 0,12346247 0,14990995 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 0,000 0,12346247 0,14983548 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,12346247 0,14976109 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,12346247 0,14968676 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,12346247 0,14961251 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,12346247 0,14953834 ! DNA modification GO:0006304 36 23 0,000 0,12346247 0,14946423 ! fatty acid transport GO:0015908 47 23 0,000 0,12346247 0,14939021 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,12346247 0,14931625 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,12346247 0,14924237 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,12346247 0,14916856 ! hormone transport GO:0009914 41 23 0,000 0,12346247 0,14909482 ! cell-cell recognition GO:0009988 28 23 0,000 0,12346247 0,14902116 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,12346247 0,14894757 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,12346247 0,14887405 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,12346247 0,1488006 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,12847182 0,15476167 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,12847182 0,1546854 GO:0016444|somatic cell DNA recombination, ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,12847182 0,1546092 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,12847182 0,15453307 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,12847182 0,15445702 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,12847182 0,15438105 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 0,12847182 0,15430515 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,12847182 0,15422932 GO:0042278|purine nucleoside metabolic process, ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,12847182 0,15415357 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,12847182 0,15407789 GO:0051693|actin filament capping, ! regulation of viral reproduction GO:0050792 41 24 0,000 0,12847182 0,15400229 ! leukotriene metabolic process GO:0006691 47 24 0,000 0,12847182 0,15392676 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,12847182 0,15385131 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,12847182 0,15377593 ! membrane depolarization GO:0051899 45 24 0,000 0,12847182 0,15370062 ! oogenesis GO:0048477 44 24 0,000 0,12847182 0,15362539 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,12847182 0,15355023 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,12847182 0,15347514 ! platelet activation GO:0030168 41 24 0,000 0,12847182 0,15340013 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,12847182 0,15332519 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,12847182 0,15325033 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,12847182 0,15317553 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,12847182 0,15310081 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,12847182 0,15302617 ! regulation of amine transport GO:0051952 41 24 0,000 0,12847182 0,15295159 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 0,000 0,12847182 0,15287709 ! myeloid leukocyte differentiation GO:0002573 46 25 0,000 0,13345269 0,15872683 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,13345269 0,15864959 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,13345269 0,15857243 ! phototransduction GO:0007602 37 25 0,000 0,13345269 0,15849534 ! keratinization GO:0031424 37 25 0,000 0,13345269 0,15841833 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 0,000 0,13345269 0,15834139 ! vacuole organization GO:0007033 49 25 0,000 0,13345269 0,15826452 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,13345269 0,15818773 ! negative regulation of DNA replication GO:0008156 45 25 0,000 0,13345269 0,15811102 ! chromosome condensation GO:0030261 48 25 0,000 0,13345269 0,15803437 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,13345269 0,15795781 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,13345269 0,15788131 ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,13345269 0,15780489 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,13345269 0,15772855 ! liver development GO:0001889 55 25 0,000 0,13345269 0,15765228 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,13840522 0,16342386 ! initiation of viral infection GO:0019059 60 26 0,000 0,13840522 0,16334491 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,13840522 0,16326603 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,13840522 0,16318724 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,13840522 0,16310852 GO:0006479|protein amino acid methylation, ! microtubule organizing center organization GO:0031023 42 26 0,000 0,13840522 0,16302987 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,13840522 0,1629513 ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,13840522 0,16287281 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,13840522 0,16279439 ! digestive system process GO:0022600 49 26 0,000 0,13840522 0,16271605 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,13840522 0,16263779 ! regulation of cellular ketone metabolic process GO:0010565 51 26 0,000 0,13840522 0,16255959 ! osteoblast differentiation GO:0001649 63 26 0,000 0,13840522 0,16248148 ! response to endoplasmic reticulum stress GO:0034976 46 26 0,000 0,13840522 0,16240344 ! neural crest cell development GO:0014032 59 26 0,000 0,13840522 0,16232547 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,13840522 0,16224758 ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,13840522 0,16216976 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,13840522 0,16209202 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,13840522 0,16201435 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,13840522 0,16193676 ! regulation of blood coagulation GO:0030193 46 26 0,000 0,13840522 0,16185924 ! regulation of osteoblast differentiation GO:0045667 68 26 0,000 0,13840522 0,1617818 ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,13840522 0,16170443 ! blastocyst development GO:0001824 50 26 0,000 0,13840522 0,16162713 ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,13840522 0,16154991 ! neural tube closure GO:0001843 58 26 0,000 0,13840522 0,16147276 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 44 26 0,000 0,13840522 0,16139568 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,13840522 0,16131868 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,14332959 0,16697863 ! embryonic pattern specification GO:0009880 49 27 0,000 0,14332959 0,16689904 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,14332959 0,16681953 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,14332959 0,16674009 ! positive regulation of cell projection organization GO:0031346 66 27 0,000 0,14332959 0,16666073 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,14332959 0,16658144 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,14332959 0,16650223 ! iron ion transport GO:0006826 65 27 0,000 0,14332959 0,16642309 ! superoxide metabolic process GO:0006801 41 27 0,000 0,14332959 0,16634403 ! tube lumen formation GO:0035148 59 27 0,000 0,14332959 0,16626505 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,14332959 0,16618614 ! mitochondrial membrane organization GO:0007006 60 27 0,000 0,14332959 0,1661073 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,14332959 0,16602854 ! response to toxin GO:0009636 49 27 0,000 0,14332959 0,16594985 ! cellular response to oxidative stress GO:0034599 43 27 0,000 0,14332959 0,16587124 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,14332959 0,1657927 ! neuron fate commitment GO:0048663 52 28 0,000 0,14822595 0,1713753 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,14822595 0,17129423 ! vesicle docking GO:0048278 55 28 0,000 0,14822595 0,17121324 ! circadian rhythm GO:0007623 56 28 0,000 0,14822595 0,17113233 ! dendrite development GO:0016358 67 28 0,000 0,14822595 0,17105149 ! fat cell differentiation GO:0045444 57 28 0,000 0,14822595 0,17097073 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,14822595 0,17089004 ! sperm motility GO:0030317 37 28 0,000 0,14822595 0,17080944 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,14822595 0,1707289 ! base-excision repair GO:0006284 41 28 0,000 0,14822595 0,17064845 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,14822595 0,17056807 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,14822595 0,17048776 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,14822595 0,17040753 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,14822595 0,17032738 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,14822595 0,1702473 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,14822595 0,17016729 ! lipid oxidation GO:0034440 48 28 0,000 0,14822595 0,17008737 GO:0019395|fatty acid oxidation, ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,14822595 0,17000751 ! translational initiation GO:0006413 66 29 0,000 0,15309447 0,17550905 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,15309447 0,17542673 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! ER-nuclear signaling pathway GO:0006984 52 29 0,000 0,15309447 0,17534448 ! autophagy GO:0006914 47 29 0,000 0,15309447 0,17526232 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,15309447 0,17518023 ! primary neural tube formation GO:0014020 61 29 0,000 0,15309447 0,17509821 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,15309447 0,17501628 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,15309447 0,17493442 ! synaptogenesis GO:0007416 46 29 0,000 0,15309447 0,17485263 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,15309447 0,17477093 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,15309447 0,1746893 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,15309447 0,17460774 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,15793529 0,18004476 ! negative regulation of protein complex assembly GO:0031333 68 30 0,000 0,15793529 0,17996078 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,15793529 0,17987688 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,15793529 0,17979306 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,15793529 0,17970932 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,15793529 0,17962566 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,15793529 0,17954207 ! acute-phase response GO:0006953 50 30 0,000 0,15793529 0,17945856 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,15793529 0,17937513 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,15793529 0,17929178 ! myofibril assembly GO:0030239 50 30 0,000 0,15793529 0,17920851 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 72 30 0,000 0,15793529 0,17912531 ! determination of left/right symmetry GO:0007368 53 30 0,000 0,15793529 0,17904219 ! cell fate determination GO:0001709 64 30 0,000 0,15793529 0,17895914 ! phospholipid transport GO:0015914 65 30 0,000 0,15793529 0,17887618 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,15793529 0,17879329 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,15793529 0,17871047 GO:0046496|nicotinamide nucleotide metabolic process, ! tissue homeostasis GO:0001894 50 30 0,000 0,15793529 0,17862774 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 52 30 0,000 0,15793529 0,17854508 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,16274858 0,18390138 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,16274858 0,18381636 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,16274858 0,18373141 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,16274858 0,18364655 ! regulation of innate immune response GO:0045088 57 31 0,000 0,16274858 0,18356176 ! ovulation cycle process GO:0022602 55 31 0,000 0,16274858 0,18347705 ! peptide transport GO:0015833 60 31 0,000 0,16274858 0,18339242 ! male gonad development GO:0008584 56 31 0,000 0,16274858 0,18330787 ! detection of light stimulus GO:0009583 44 31 0,000 0,16274858 0,1832234 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 0,000 0,16274858 0,183139 ! natural killer cell activation GO:0030101 50 31 0,000 0,16274858 0,18305469 ! cofactor catabolic process GO:0051187 54 31 0,000 0,16274858 0,18297044 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,16274858 0,18288628 ! eye morphogenesis GO:0048592 65 31 0,000 0,16274858 0,1828022 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,16753449 0,18809134 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,16753449 0,18800494 ! collagen metabolic process GO:0032963 49 32 0,000 0,16753449 0,18791862 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,16753449 0,18783238 ! metanephros development GO:0001656 81 32 0,000 0,16753449 0,18774622 ! muscle cell development GO:0055001 52 32 0,000 0,16753449 0,18766014 ! mesoderm formation GO:0001707 73 32 0,000 0,16753449 0,18757413 ! hexose biosynthetic process GO:0019319 53 32 0,000 0,16753449 0,18748821 ! ovulation cycle GO:0042698 57 32 0,000 0,16753449 0,18740236 ! BMP signaling pathway GO:0030509 71 32 0,000 0,16753449 0,18731659 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,16753449 0,1872309 ! gene silencing GO:0016458 71 32 0,000 0,16753449 0,18714529 ! regulation of pH GO:0006885 56 33 0,000 0,17229318 0,19237305 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,17229318 0,19228517 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,17229318 0,19219736 GO:0055092|sterol homeostasis, ! pigment biosynthetic process GO:0046148 73 33 0,000 0,17229318 0,19210964 ! positive regulation of gene-specific transcription GO:0043193 70 33 0,000 0,17229318 0,192022 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,17229318 0,19193444 ! triglyceride metabolic process GO:0006641 46 33 0,000 0,17229318 0,19184696 ! response to ionizing radiation GO:0010212 74 33 0,000 0,17229318 0,19175956 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,17229318 0,19167224 ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,17229318 0,19158499 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,17229318 0,19149783 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,17229318 0,19141075 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,17702479 0,19657799 ! glial cell differentiation GO:0010001 67 34 0,000 0,17702479 0,19648867 ! post-embryonic development GO:0009791 76 34 0,000 0,17702479 0,19639944 ! cholesterol transport GO:0030301 62 34 0,000 0,17702479 0,19631029 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,17702479 0,19622122 ! spliceosome assembly GO:0000245 75 34 0,000 0,17702479 0,19613223 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,17702479 0,19604332 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,17702479 0,1959545 ! formation of primary germ layer GO:0001704 76 34 0,000 0,17702479 0,19586575 ! cell fate specification GO:0001708 56 34 0,000 0,17702479 0,19577708 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,17702479 0,19568849 ! adult locomotory behavior GO:0008344 62 34 0,000 0,17702479 0,19559999 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,1817295 0,20070758 ! negative regulation of secretion GO:0051048 68 35 0,000 0,1817295 0,20061688 ! negative regulation of DNA metabolic process GO:0051053 65 35 0,000 0,1817295 0,20052627 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,1817295 0,20043574 ! membrane docking GO:0022406 69 35 0,000 0,1817295 0,20034529 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,1817295 0,20025492 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,1817295 0,20016463 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,1817295 0,20007443 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,1817295 0,19998431 ! ceramide metabolic process GO:0006672 72 35 0,000 0,1817295 0,19989426 ! sterol transport GO:0015918 63 35 0,000 0,1817295 0,1998043 ! vesicle localization GO:0051648 70 35 0,000 0,1817295 0,19971442 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,18640743 0,2047632 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,18640743 0,20467117 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,18640743 0,20457923 ! protein targeting to membrane GO:0006612 75 36 0,000 0,18640743 0,20448736 ! aerobic respiration GO:0009060 56 36 0,000 0,18640743 0,20439558 ! cytokine production GO:0001816 68 36 0,000 0,18640743 0,20430389 ! embryonic organ development GO:0048568 67 36 0,000 0,18640743 0,20421227 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,18640743 0,20412074 ! monosaccharide biosynthetic process GO:0046364 57 36 0,000 0,18640743 0,20402928 ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,19105876 0,20902667 ! odontogenesis GO:0042476 74 37 0,000 0,19105876 0,2089331 ! actomyosin structure organization GO:0031032 68 37 0,000 0,19105876 0,20883962 ! female gonad development GO:0008585 71 37 0,000 0,19105876 0,20874622 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,19105876 0,20865291 ! regulation of microtubule-based process GO:0032886 86 37 0,000 0,19105876 0,20855967 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,19568363 0,21351277 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,19568363 0,21341745 ! organic anion transport GO:0015711 82 38 0,000 0,19568363 0,21332222 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,19568363 0,21322707 ! neutral lipid metabolic process GO:0006638 54 38 0,000 0,19568363 0,21313201 GO:0006639|acylglycerol metabolic process, ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,19568363 0,21303703 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,19568363 0,21294214 ! spermatid development GO:0007286 69 38 0,000 0,19568363 0,21284733 ! pigment metabolic process GO:0042440 87 38 0,000 0,19568363 0,2127526 ! neural tube formation GO:0001841 79 38 0,000 0,19568363 0,21265796 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,20028218 0,21755863 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,20028218 0,21746194 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,20028218 0,21736533 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,20028218 0,21726881 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,20485457 0,22213036 GO:0006956|complement activation, ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,20485457 0,22203181 ! learning GO:0007612 82 40 0,000 0,20485457 0,22193335 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,20485457 0,22183498 GO:0046660|female sex differentiation, ! lipid homeostasis GO:0055088 75 40 0,000 0,20485457 0,22173669 ! mismatch repair GO:0006298 58 40 0,000 0,20485457 0,22163849 ! glycerol ether metabolic process GO:0006662 57 40 0,000 0,20485457 0,22154038 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,20485457 0,22144235 ! RNA export from nucleus GO:0006405 61 41 0,000 0,20940094 0,22625675 ! mRNA catabolic process GO:0006402 79 41 0,000 0,20940094 0,22615672 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,20940094 0,22605679 ! regulation of hormone secretion GO:0046883 69 41 0,000 0,20940094 0,22595694 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,20940094 0,22585718 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,20940094 0,22575751 ! feeding behavior GO:0007631 69 41 0,000 0,20940094 0,22565792 ! multicellular organismal metabolic process GO:0044236 64 41 0,000 0,20940094 0,22555842 ! monovalent inorganic cation homeostasis GO:0055067 72 41 0,000 0,20940094 0,22545902 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,20940094 0,22535969 GO:0015986|ATP synthesis coupled proton transport, ! spermatid differentiation GO:0048515 73 41 0,000 0,20940094 0,22526046 ! embryonic epithelial tube formation GO:0001838 85 41 0,000 0,20940094 0,22516131 ! RNA modification GO:0009451 64 41 0,000 0,20940094 0,22506226 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,21392145 0,22981975 ! organic ether metabolic process GO:0018904 59 42 0,000 0,21392145 0,22971873 ! alcohol biosynthetic process GO:0046165 65 42 0,000 0,21392145 0,2296178 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,21392145 0,22951696 ! regulation of protein secretion GO:0050708 77 42 0,000 0,21392145 0,2294162 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,21392145 0,22931554 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,21841624 0,23403109 ! regulation of tube size GO:0035150 76 43 0,000 0,21841624 0,23392848 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,21841624 0,23382597 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,21841624 0,23372355 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,21841624 0,23362122 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,21841624 0,23351898 ! ion transmembrane transport GO:0034220 79 43 0,000 0,21841624 0,23341683 ! neuron migration GO:0001764 85 43 0,000 0,21841624 0,23331477 ! response to reactive oxygen species GO:0000302 75 44 0,000 0,22288545 0,23798477 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,22288545 0,2378808 ! negative regulation of protein complex disassembly GO:0043242 113 44 0,000 0,22288545 0,23777693 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 0,000 0,22288545 0,23767314 ! striated muscle contraction GO:0006941 85 44 0,000 0,22288545 0,23756944 ! phagocytosis GO:0006909 105 44 0,000 0,22288545 0,23746584 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,22288545 0,23736232 ! double-strand break repair GO:0006302 85 44 0,000 0,22288545 0,23725889 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,22732923 0,24188385 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,22732923 0,24177855 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! keratinocyte differentiation GO:0030216 81 45 0,000 0,22732923 0,24167333 ! biopolymer methylation GO:0043414 91 45 0,000 0,22732923 0,24156821 ! B cell differentiation GO:0030183 124 45 0,000 0,22732923 0,24146318 ! female gamete generation GO:0007292 71 45 0,000 0,22732923 0,24135824 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,22732923 0,2412534 ! polyol metabolic process GO:0019751 77 45 0,000 0,22732923 0,24114864 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,23174773 0,24572904 ! negative regulation of cell migration GO:0030336 122 46 0,000 0,23174773 0,24562243 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,23174773 0,24551592 ! neural tube development GO:0021915 91 47 0,000 0,23614108 0,25006184 ! positive regulation of defense response GO:0031349 88 48 0,000 0,24050943 0,25457736 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,24050943 0,2544671 ! mitochondrial transport GO:0006839 94 48 0,000 0,24050943 0,25435695 ! regulation of JAK-STAT cascade GO:0046425 76 48 0,000 0,24050943 0,25424688 ! male sex differentiation GO:0046661 93 48 0,000 0,24050943 0,25413691 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,24050943 0,25402704 ! regulation of inflammatory response GO:0050727 84 48 0,000 0,24050943 0,25391726 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,24050943 0,25380758 ! methylation GO:0032259 97 48 0,000 0,24050943 0,25369799 ! response to calcium ion GO:0051592 94 49 0,000 0,24485292 0,25816819 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,24485292 0,25805681 ! protein homooligomerization GO:0051260 84 49 0,000 0,24485292 0,25794553 ! regulation of ion transport GO:0043269 86 50 0,000 0,2491717 0,26238209 ! induction of apoptosis by extracellular signals GO:0008624 99 50 0,000 0,2491717 0,26226905 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,2491717 0,2621561 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,2491717 0,26204324 GO:0019724|B cell mediated immunity, ! regulation of gene expression, epigenetic GO:0040029 116 50 0,000 0,2491717 0,26193049 ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,2491717 0,26181783 ! epidermal cell differentiation GO:0009913 87 50 0,000 0,2491717 0,26170527 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,2491717 0,2615928 ! regulation of cell projection organization GO:0031344 135 51 0,000 0,25346589 0,26598676 ! response to estrogen stimulus GO:0043627 98 52 0,000 0,25773565 0,2703513 ! Notch signaling pathway GO:0007219 111 52 0,000 0,25773565 0,27023527 ! regulation of protein complex disassembly GO:0043244 127 52 0,000 0,25773565 0,27011934 ! morphogenesis of embryonic epithelium GO:0016331 106 52 0,000 0,25773565 0,27000351 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,25773565 0,26988778 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,25773565 0,26977215 ! excretion GO:0007588 87 52 0,000 0,25773565 0,26965661 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,25773565 0,26954118 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,25773565 0,26942584 ! amino acid activation GO:0043038 98 52 0,000 0,25773565 0,2693106 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,2619811 0,27362968 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,2619811 0,27351275 ! vesicle organization GO:0016050 127 53 0,000 0,2619811 0,27339591 ! regulation of translational initiation GO:0006446 87 54 0,000 0,26620239 0,27768251 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,26620239 0,277564 ! neuromuscular process GO:0050905 107 54 0,000 0,26620239 0,27744558 ! regulation of muscle contraction GO:0006937 94 54 0,000 0,26620239 0,27732727 ! membrane fusion GO:0006944 122 54 0,000 0,26620239 0,27720906 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,26620239 0,27709094 ! epithelial tube morphogenesis GO:0060562 114 54 0,000 0,26620239 0,27697293 ! RNA catabolic process GO:0006401 103 55 0,000 0,27039966 0,28122025 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,27039966 0,28110058 ! negative regulation of cell motion GO:0051271 142 55 0,000 0,27039966 0,28098101 ! negative regulation of cytoskeleton organization GO:0051494 139 56 0,000 0,27457303 0,28519639 ! RNA elongation GO:0006354 90 56 0,000 0,27457303 0,28507519 ! chloride transport GO:0006821 102 57 0,000 0,27872265 0,28926059 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,28284865 0,29341794 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,28284865 0,2932934 ! gastrulation GO:0007369 122 58 0,000 0,28284865 0,29316896 ! nuclear export GO:0051168 110 59 0,000 0,28695116 0,29729503 ! regulation of endocytosis GO:0030100 104 60 0,000 0,29103032 0,30139342 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,29103032 0,30126571 ! adult behavior GO:0030534 104 60 0,000 0,29103032 0,30113811 ! kidney development GO:0001822 133 60 0,000 0,29103032 0,30101061 ! positive regulation of secretion GO:0051047 110 61 0,000 0,29508625 0,30507648 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,29508625 0,30494743 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,29508625 0,30481849 ! proton transport GO:0015992 117 61 0,000 0,29508625 0,30468965 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,2991191 0,30872326 ! tRNA processing GO:0008033 102 62 0,000 0,2991191 0,30859289 ! mesoderm development GO:0007498 128 63 0,000 0,30312899 0,31259777 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,30312899 0,31246587 ! hydrogen transport GO:0006818 121 64 0,000 0,30711605 0,31644222 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,30711605 0,31630881 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,3110804 0,32025682 ! lymphocyte mediated immunity GO:0002449 122 65 0,000 0,3110804 0,32012192 ! multicellular organism reproduction GO:0032504 123 65 0,000 0,3110804 0,31998713 GO:0048609|reproductive process in a multicellular organism, ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,3110804 0,31985245 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,3110804 0,31971789 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,31502219 0,32363298 ! gonad development GO:0008406 115 66 0,000 0,31502219 0,32349694 ! embryonic limb morphogenesis GO:0030326 139 67 0,000 0,31894154 0,32738411 GO:0035113|embryonic appendage morphogenesis, ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,31894154 0,32724661 ! secondary metabolic process GO:0019748 125 67 0,000 0,31894154 0,32710922 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,3267134 0,33493951 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,3267134 0,33479901 ! single fertilization GO:0007338 83 69 0,000 0,3267134 0,33465863 ! cell redox homeostasis GO:0045454 114 70 0,000 0,33056618 0,33846319 ! protein maturation by peptide bond cleavage GO:0051605 118 70 0,000 0,33056618 0,3383214 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,33439701 0,34209879 ! appendage morphogenesis GO:0035107 150 72 0,000 0,33820603 0,34585071 GO:0035108|limb morphogenesis, ! B cell activation GO:0042113 179 72 0,000 0,33820603 0,345706 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,33820603 0,34556141 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,33820603 0,34541695 ! appendage development GO:0048736 151 73 0,000 0,34199336 0,34913907 GO:0060173|limb development, ! humoral immune response GO:0006959 115 73 0,000 0,34199336 0,34899323 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,34199336 0,34884751 ! acute inflammatory response GO:0002526 118 74 0,000 0,34575913 0,35254155 ! amino acid transport GO:0006865 148 74 0,000 0,34575913 0,35239447 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 0,000 0,34575913 0,35224752 ! transition metal ion transport GO:0000041 143 75 0,000 0,34950344 0,35591368 ! leukocyte mediated immunity GO:0002443 136 75 0,000 0,34950344 0,35576538 ! rhythmic process GO:0048511 142 75 0,000 0,34950344 0,35561721 ! learning or memory GO:0007611 161 76 0,000 0,35322643 0,3592557 ! regulation of blood pressure GO:0008217 134 76 0,000 0,35322643 0,35910619 ! amine catabolic process GO:0009310 136 77 0,000 0,35692822 0,36271866 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,35692822 0,36256784 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,36060893 0,36615445 ! antigen processing and presentation GO:0019882 117 78 0,000 0,36060893 0,36600233 ! fertilization GO:0009566 99 78 0,000 0,36060893 0,36585034 ! blood coagulation GO:0007596 151 79 0,000 0,36426867 0,36940986 GO:0050817|coagulation, ! steroid biosynthetic process GO:0006694 146 79 0,000 0,36426867 0,36925658 ! response to steroid hormone stimulus GO:0048545 147 79 0,000 0,36426867 0,36910343 ! development of primary sexual characteristics GO:0045137 143 80 0,000 0,36790757 0,37263606 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 0,000 0,37152574 0,37614479 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,37870036 0,38324979 ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,37870036 0,38309109 ! inorganic anion transport GO:0015698 156 83 0,000 0,37870036 0,38293253 ! response to metal ion GO:0010038 158 84 0,000 0,38225705 0,38636905 ! digestion GO:0007586 130 84 0,000 0,38225705 0,38620926 ! hemostasis GO:0007599 165 85 0,000 0,38579349 0,38962112 ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,39280602 0,3965393 ! nucleosome assembly GO:0006334 126 87 0,000 0,39280602 0,39637551 ! cellular respiration GO:0045333 143 88 0,000 0,39628236 0,39971833 ! sensory perception of smell GO:0007608 117 88 0,000 0,39628236 0,39955336 ! chromatin assembly GO:0031497 128 88 0,000 0,39628236 0,39938853 ! one-carbon metabolic process GO:0006730 167 88 0,000 0,39628236 0,39922383 ! cellular defense response GO:0006968 123 89 0,000 0,39973888 0,40254002 ! response to inorganic substance GO:0010035 173 90 0,000 0,40317572 0,40583366 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,40317572 0,40566651 ! positive regulation of protein modification process GO:0031401 156 90 0,000 0,40317572 0,4054995 ! response to unfolded protein GO:0006986 139 90 0,000 0,40317572 0,40533263 ! defense response to bacterium GO:0042742 112 91 0,000 0,40659297 0,40860001 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,40999076 0,41184516 ! amine transport GO:0015837 181 93 0,000 0,41336918 0,41506819 ! vitamin metabolic process GO:0006766 153 93 0,000 0,41336918 0,41489766 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,41672836 0,41809748 ! female pregnancy GO:0007565 166 94 0,000 0,41672836 0,41792585 ! regulation of defense response GO:0031347 171 95 0,000 0,42006839 0,42110261 ! nucleosome organization GO:0034728 143 95 0,000 0,42006839 0,42092989 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,42006839 0,42075731 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,42006839 0,42058486 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,42006839 0,42041256 ! response to protein stimulus GO:0051789 158 96 0,000 0,42338939 0,42356277 ! mRNA transport GO:0051028 185 100 0,000 0,43648521 0,43648521