pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6786-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! induction of apoptosis by intracellular signals GO:0008629 93 45 4,000 1,885E-07 4,534E-04 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 4,000 6,287E-07 7,563E-04 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 3,000 7,487E-07 6,005E-04 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 3,000 8,829E-07 5,311E-04 ! peptidyl-tyrosine modification GO:0018212 50 28 3,000 1,204E-06 5,794E-04 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 2,000 1,246E-06 4,996E-04 ! negative regulation of protein kinase activity GO:0006469 130 67 4,000 1,418E-06 4,874E-04 ! negative regulation of kinase activity GO:0033673 131 68 4,000 1,527E-06 4,593E-04 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 2,000 1,865E-06 4,986E-04 ! negative regulation of transferase activity GO:0051348 140 72 4,000 2,032E-06 4,888E-04 ! positive regulation of MAP kinase activity GO:0043406 160 93 4,000 7,2E-06 1,575E-03 ! interphase of mitotic cell cycle GO:0051329 209 95 4,000 7,991E-06 1,602E-03 ! release of cytochrome c from mitochondria GO:0001836 30 14 2,000 7,999E-06 1,48E-03 ! interphase GO:0051325 213 98 4,000 9,303E-06 1,599E-03 ! cell cycle arrest GO:0007050 213 100 4,000 1,027E-05 1,647E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 2,000 1,485E-05 2,233E-03 ! positive regulation of growth GO:0045927 90 52 3,000 1,511E-05 2,138E-03 ! response to UV GO:0009411 104 53 3,000 1,631E-05 2,18E-03 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 2,000 2,474E-05 3,133E-03 ! apoptotic mitochondrial changes GO:0008637 41 20 2,000 2,474E-05 2,977E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 2,000 2,474E-05 2,835E-03 ! DNA damage response, signal transduction GO:0042770 128 60 3,000 2,675E-05 2,925E-03 ! protein amino acid autophosphorylation GO:0046777 141 60 3,000 2,675E-05 2,798E-03 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 2,000 3,329E-05 3,337E-03 ! protein import into nucleus, translocation GO:0000060 46 24 2,000 4,357E-05 4,193E-03 ! regulation of oxidoreductase activity GO:0051341 46 24 2,000 4,357E-05 4,032E-03 ! protein tetramerization GO:0051262 52 24 2,000 4,357E-05 3,882E-03 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 2,000 4,941E-05 4,245E-03 ! osteoblast differentiation GO:0001649 60 25 2,000 4,941E-05 4,099E-03 ! insulin receptor signaling pathway GO:0008286 64 26 2,000 5,574E-05 4,47E-03 ! regulation of fibroblast proliferation GO:0048145 52 27 2,000 6,257E-05 4,857E-03 ! cellular response to extracellular stimulus GO:0031668 48 29 2,000 7,785E-05 5,853E-03 ! 2-oxoglutarate metabolic process GO:0006103 7 5 1,000 8,015E-05 5,843E-03 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 1,000 8,015E-05 5,672E-03 ! positive regulation of glycolysis GO:0045821 14 5 1,000 8,015E-05 5,509E-03 ! parathyroid gland development GO:0060017 13 5 1,000 8,015E-05 5,356E-03 ! valine metabolic process GO:0006573 10 5 1,000 8,015E-05 5,212E-03 ! morphogenesis of an epithelial sheet GO:0002011 11 5 1,000 8,015E-05 5,075E-03 ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 8,015E-05 4,944E-03 ! regulation of sensory perception GO:0051931 7 5 1,000 8,015E-05 4,821E-03 GO:0051930|regulation of sensory perception of pain, ! cellular response to hormone stimulus GO:0032870 167 82 3,000 9,146E-05 5,367E-03 ! forebrain regionalization GO:0021871 8 6 1,000 1,2E-04 6,874E-03 ! neurofilament cytoskeleton organization GO:0060052 12 6 1,000 1,2E-04 6,714E-03 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 1,000 1,2E-04 6,562E-03 ! activation of MAPKKK activity GO:0000185 12 6 1,000 1,2E-04 6,416E-03 ! male sex determination GO:0030238 15 6 1,000 1,2E-04 6,276E-03 ! negative regulation of neuroblast proliferation GO:0007406 21 6 1,000 1,2E-04 6,143E-03 ! ectodermal gut morphogenesis GO:0048567 12 6 1,000 1,2E-04 6,015E-03 GO:0007439|ectodermal gut development, ! gland development GO:0048732 206 88 3,000 1,204E-04 5,91E-03 ! ossification GO:0001503 188 90 3,000 1,313E-04 6,319E-03 ! bone development GO:0060348 189 91 3,000 1,371E-04 6,466E-03 ! negative regulation of hydrolase activity GO:0051346 62 35 2,000 1,377E-04 6,372E-03 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 2,000 1,499E-04 6,806E-03 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! cellular response to insulin stimulus GO:0032869 82 37 2,000 1,628E-04 7,255E-03 ! regulation of helicase activity GO:0051095 15 7 1,000 1,677E-04 7,335E-03 ! N-terminal protein amino acid acetylation GO:0006474 13 7 1,000 1,677E-04 7,204E-03 ! oxaloacetate metabolic process GO:0006107 10 7 1,000 1,677E-04 7,078E-03 ! spinal cord patterning GO:0021511 13 7 1,000 1,677E-04 6,956E-03 ! G1 DNA damage checkpoint GO:0031571 21 7 1,000 1,677E-04 6,838E-03 ! B cell lineage commitment GO:0002326 21 7 1,000 1,677E-04 6,724E-03 ! cranial nerve morphogenesis GO:0021602 11 7 1,000 1,677E-04 6,614E-03 ! T cell lineage commitment GO:0002360 16 7 1,000 1,677E-04 6,507E-03 ! response to tumor cell GO:0002347 13 7 1,000 1,677E-04 6,404E-03 ! regulation of respiratory burst GO:0060263 11 7 1,000 1,677E-04 6,304E-03 ! mammary gland development GO:0030879 86 39 2,000 1,907E-04 7,06E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 2,232E-04 8,135E-03 ! succinate metabolic process GO:0006105 14 8 1,000 2,232E-04 8,014E-03 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 2,232E-04 7,896E-03 ! ER overload response GO:0006983 12 8 1,000 2,232E-04 7,782E-03 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 1,000 2,232E-04 7,67E-03 ! neural tube development GO:0021915 77 43 2,000 2,554E-04 8,656E-03 ! regulation of epithelial cell proliferation GO:0050678 111 43 2,000 2,554E-04 8,536E-03 ! regulation of developmental growth GO:0048638 15 9 1,000 2,864E-04 9,439E-03 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 2,864E-04 9,312E-03 ! regulation of glycolysis GO:0006110 21 9 1,000 2,864E-04 9,187E-03 ! keratinocyte proliferation GO:0043616 14 9 1,000 2,864E-04 9,066E-03 ! microtubule bundle formation GO:0001578 21 9 1,000 2,864E-04 8,949E-03 ! phosphagen metabolic process GO:0006599 12 9 1,000 2,864E-04 8,834E-03 GO:0006600|creatine metabolic process, ! motor axon guidance GO:0008045 16 9 1,000 2,864E-04 8,722E-03 ! protein heterooligomerization GO:0051291 16 9 1,000 2,864E-04 8,613E-03 ! spinal cord motor neuron differentiation GO:0021522 15 9 1,000 2,864E-04 8,507E-03 ! S phase GO:0051320 9 9 1,000 2,864E-04 8,403E-03 GO:0000084|S phase of mitotic cell cycle, ! G1/S transition of mitotic cell cycle GO:0000082 115 46 2,000 3,123E-04 9,052E-03 ! response to insulin stimulus GO:0032868 95 46 2,000 3,123E-04 8,944E-03 ! regulation of gene-specific transcription GO:0032583 96 46 2,000 3,123E-04 8,839E-03 ! positive regulation of DNA binding GO:0043388 73 47 2,000 3,329E-04 9,313E-03 ! regulation of mast cell proliferation GO:0070666 81 48 2,000 3,543E-04 9,799E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 1,000 3,573E-04 9,769E-03 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 3,573E-04 9,66E-03 ! smoothened signaling pathway GO:0007224 16 10 1,000 3,573E-04 9,552E-03 ! negative regulation of striated muscle development GO:0045843 19 10 1,000 3,573E-04 9,447E-03 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 1,000 3,573E-04 9,345E-03 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 1,000 3,573E-04 9,244E-03 GO:0043470|regulation of carbohydrate catabolic process, ! localization within membrane GO:0051668 20 10 1,000 3,573E-04 9,146E-03 ! positive regulation of binding GO:0051099 78 51 2,000 4,24E-04 0,0107384 ! regulation of leukocyte proliferation GO:0070663 88 51 2,000 4,24E-04 0,01062654 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! epithelial tube morphogenesis GO:0060562 98 51 2,000 4,24E-04 0,01051699 ! negative regulation of muscle development GO:0048635 20 11 1,000 4,359E-04 0,01070216 ! neuron fate specification GO:0048665 17 11 1,000 4,359E-04 0,01059406 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 1,000 4,359E-04 0,01048812 ! peptide or protein amino-terminal blocking GO:0018409 21 11 1,000 4,359E-04 0,01038428 ! ventral spinal cord development GO:0021517 21 11 1,000 4,359E-04 0,01028247 ! regulation of intracellular pH GO:0051453 19 11 1,000 4,359E-04 0,01018264 ! thymus development GO:0048538 27 11 1,000 4,359E-04 0,01008473 ! embryonic gut development GO:0048566 15 11 1,000 4,359E-04 9,989E-03 ! regulation of embryonic development GO:0045995 27 11 1,000 4,359E-04 9,894E-03 ! positive regulation of cellular catabolic process GO:0031331 31 12 1,000 5,221E-04 0,01174055 ! virus-host interaction GO:0019048 29 12 1,000 5,221E-04 0,01163184 ! regulation of B cell proliferation GO:0030888 20 12 1,000 5,221E-04 0,01152512 ! positive regulation of cell growth GO:0030307 22 12 1,000 5,221E-04 0,01142035 ! nucleotide-sugar metabolic process GO:0009225 19 12 1,000 5,221E-04 0,01131746 ! cranial nerve development GO:0021545 20 12 1,000 5,221E-04 0,01121642 ! histone acetylation GO:0016573 26 12 1,000 5,221E-04 0,01111716 ! peptidyl-lysine modification GO:0018205 21 12 1,000 5,221E-04 0,01101964 ! digestive tract morphogenesis GO:0048546 26 12 1,000 5,221E-04 0,01092381 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! negative regulation of mast cell proliferation GO:0070667 23 12 1,000 5,221E-04 0,01082964 GO:0042130|negative regulation of T cell proliferation, ! regulation of DNA replication GO:0006275 101 56 2,000 5,586E-04 0,0114873 ! positive regulation of cell migration GO:0030335 126 57 2,000 5,884E-04 0,01199802 ! response to X-ray GO:0010165 25 13 1,000 6,159E-04 0,01245286 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 1,000 6,159E-04 0,01234909 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of cellular pH GO:0030641 22 13 1,000 6,159E-04 0,01224703 ! regulation of monooxygenase activity GO:0032768 33 13 1,000 6,159E-04 0,01214664 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 1,000 7,172E-04 0,0140298 GO:0060675|ureteric bud morphogenesis, ! N-terminal protein amino acid modification GO:0031365 27 14 1,000 7,172E-04 0,01391665 ! negative regulation of caspase activity GO:0043154 22 14 1,000 7,172E-04 0,01380532 ! response to gamma radiation GO:0010332 28 14 1,000 7,172E-04 0,01369575 ! response to peptide hormone stimulus GO:0043434 122 61 2,000 7,178E-04 0,01359951 ! positive regulation of cell motion GO:0051272 146 64 2,000 8,259E-04 0,01552452 ! positive regulation of cell size GO:0045793 27 15 1,000 8,26E-04 0,01540665 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 1,000 8,26E-04 0,01528814 ! G1/S transition checkpoint GO:0031575 40 15 1,000 8,26E-04 0,01517144 ! intermediate filament cytoskeleton organization GO:0045104 31 15 1,000 8,26E-04 0,0150565 ! positive regulation of oxidoreductase activity GO:0051353 22 15 1,000 8,26E-04 0,0149433 ! embryonic limb morphogenesis GO:0030326 125 65 2,000 8,641E-04 0,01551503 GO:0035113|embryonic appendage morphogenesis, ! regulation of glucose metabolic process GO:0010906 28 16 1,000 9,423E-04 0,01679384 ! embryonic forelimb morphogenesis GO:0035115 28 16 1,000 9,423E-04 0,01667036 ! startle response GO:0001964 28 16 1,000 9,423E-04 0,01654868 ! activation of MAPKK activity GO:0000186 35 16 1,000 9,423E-04 0,01642876 ! negative regulation of microtubule depolymerization GO:0007026 46 16 1,000 9,423E-04 0,01631057 GO:0031114|regulation of microtubule depolymerization, ! intermediate filament-based process GO:0045103 32 16 1,000 9,423E-04 0,01619406 ! positive regulation of protein import into nucleus GO:0042307 30 16 1,000 9,423E-04 0,01607921 ! negative regulation of leukocyte proliferation GO:0070664 31 16 1,000 9,423E-04 0,01596598 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 9,423E-04 0,01585433 ! negative regulation of cell growth GO:0030308 132 67 2,000 9,438E-04 0,01576916 ! activation of MAPK activity GO:0000187 115 67 2,000 9,438E-04 0,01566041 ! lung development GO:0030324 144 67 2,000 9,438E-04 0,01555315 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 2,000 9,438E-04 0,01544734 ! negative regulation of cell size GO:0045792 134 69 2,000 1,028E-03 0,01671191 ! negative regulation of peptidase activity GO:0010466 27 17 1,000 1,066E-03 0,01721271 ! cell differentiation in spinal cord GO:0021515 30 17 1,000 1,066E-03 0,01709796 ! branched chain family amino acid metabolic process GO:0009081 33 17 1,000 1,066E-03 0,01698473 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 1,000 1,066E-03 0,01687299 ! appendage morphogenesis GO:0035107 135 70 2,000 1,072E-03 0,01685496 GO:0035108|limb morphogenesis, ! respiratory tube development GO:0030323 150 70 2,000 1,072E-03 0,01674551 ! appendage development GO:0048736 136 71 2,000 1,117E-03 0,01733585 GO:0060173|limb development, ! regulation of caspase activity GO:0043281 122 72 2,000 1,163E-03 0,01793675 ! respiratory system development GO:0060541 153 72 2,000 1,163E-03 0,01782251 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 1,197E-03 0,01822742 ! centrosome cycle GO:0007098 25 18 1,000 1,197E-03 0,01811278 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 1,000 1,197E-03 0,01799958 ! nerve development GO:0021675 28 18 1,000 1,197E-03 0,01788778 ! regulation of endopeptidase activity GO:0052548 125 74 2,000 1,259E-03 0,01869685 ! skin development GO:0043588 36 19 1,000 1,335E-03 0,01971032 ! lipid phosphorylation GO:0046834 35 19 1,000 1,335E-03 0,01959014 ! forelimb morphogenesis GO:0035136 32 19 1,000 1,335E-03 0,01947141 ! neuromuscular junction development GO:0007528 34 19 1,000 1,335E-03 0,01935411 ! proximal/distal pattern formation GO:0009954 32 19 1,000 1,335E-03 0,01923822 ! embryonic organ morphogenesis GO:0048562 26 19 1,000 1,335E-03 0,0191237 ! protein oligomerization GO:0051259 139 78 2,000 1,465E-03 0,02086142 ! protein amino acid acetylation GO:0006473 39 20 1,000 1,481E-03 0,02095967 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 1,000 1,481E-03 0,0208371 ! regulation of carbohydrate metabolic process GO:0006109 38 20 1,000 1,481E-03 0,02071595 GO:0010675|regulation of cellular carbohydrate metabolic process, ! cellular response to starvation GO:0009267 33 20 1,000 1,481E-03 0,02059621 ! camera-type eye morphogenesis GO:0048593 42 20 1,000 1,481E-03 0,02047784 ! negative regulation of T cell activation GO:0050868 40 20 1,000 1,481E-03 0,02036082 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 1,000 1,481E-03 0,02024513 ! activation of protein kinase activity GO:0032147 147 79 2,000 1,52E-03 0,02066236 ! regulation of peptidase activity GO:0052547 134 79 2,000 1,52E-03 0,02054628 ! positive regulation of phosphorylation GO:0042327 129 79 2,000 1,52E-03 0,02043149 ! regulation of adenylate cyclase activity GO:0045761 156 80 2,000 1,576E-03 0,02106634 ! protein import into nucleus GO:0006606 158 80 2,000 1,576E-03 0,02094995 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 2,000 1,633E-03 0,02159185 GO:0045937|positive regulation of phosphate metabolic process, ! nuclear import GO:0051170 161 81 2,000 1,633E-03 0,02147386 ! hindlimb morphogenesis GO:0035137 43 21 1,000 1,634E-03 0,02136367 ! cell aging GO:0007569 44 21 1,000 1,634E-03 0,02124819 ! gut development GO:0048565 39 21 1,000 1,634E-03 0,02113395 ! regulation of cAMP biosynthetic process GO:0030817 161 82 2,000 1,692E-03 0,02176786 ! regulation of cyclase activity GO:0031279 159 82 2,000 1,692E-03 0,02165207 ! regulation of lyase activity GO:0051339 160 83 2,000 1,752E-03 0,0222994 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 1,000 1,794E-03 0,02271578 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 1,000 1,794E-03 0,02259685 ! ureteric bud development GO:0001657 43 22 1,000 1,794E-03 0,02247916 ! positive regulation of intracellular transport GO:0032388 37 22 1,000 1,794E-03 0,02236269 ! positive regulation of B cell activation GO:0050871 38 22 1,000 1,794E-03 0,02224741 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 1,000 1,794E-03 0,02213333 ! regulation of cAMP metabolic process GO:0030814 168 84 2,000 1,813E-03 0,02225372 ! negative regulation of growth GO:0045926 155 84 2,000 1,813E-03 0,02214076 ! tube morphogenesis GO:0035239 176 86 2,000 1,939E-03 0,02356343 ! mitochondrion organization GO:0007005 148 86 2,000 1,939E-03 0,02344502 ! positive regulation of DNA replication GO:0045740 43 23 1,000 1,961E-03 0,02359146 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 1,000 1,961E-03 0,02347409 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 1,961E-03 0,02335788 ! sex determination GO:0007530 47 23 1,000 1,961E-03 0,02324282 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 1,000 1,961E-03 0,02312889 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 2,000 2,004E-03 0,02352338 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! protein localization in nucleus GO:0034504 176 87 2,000 2,004E-03 0,02340919 ! regulation of DNA binding GO:0051101 155 88 2,000 2,071E-03 0,02406894 ! positive regulation of fibroblast proliferation GO:0048146 43 24 1,000 2,135E-03 0,02470047 ! regulation of cellular catabolic process GO:0031329 52 24 1,000 2,135E-03 0,02458229 ! spinal cord development GO:0021510 47 24 1,000 2,135E-03 0,02446523 ! negative regulation of phosphorylation GO:0042326 47 24 1,000 2,135E-03 0,02434928 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 2,000 2,208E-03 0,02505685 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 1,000 2,317E-03 0,02616957 ! myelination GO:0042552 45 25 1,000 2,317E-03 0,02604728 ! dicarboxylic acid metabolic process GO:0043648 42 25 1,000 2,317E-03 0,02592613 ! negative regulation of DNA replication GO:0008156 42 25 1,000 2,317E-03 0,0258061 ! response to starvation GO:0042594 42 25 1,000 2,317E-03 0,02568718 ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 2,317E-03 0,02556935 ! negative regulation of cell development GO:0010721 73 25 1,000 2,317E-03 0,0254526 GO:0050768|negative regulation of neurogenesis, ! interaction with host GO:0051701 62 25 1,000 2,317E-03 0,0253369 ! somitogenesis GO:0001756 43 25 1,000 2,317E-03 0,02522226 ! cellular response to nutrient levels GO:0031669 41 25 1,000 2,317E-03 0,02510864 ! neural tube closure GO:0001843 49 25 1,000 2,317E-03 0,02499605 GO:0060606|tube closure, ! regulation of nucleotide metabolic process GO:0006140 182 93 2,000 2,424E-03 0,02603411 ! tube lumen formation GO:0035148 50 26 1,000 2,505E-03 0,02678868 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 1,000 2,505E-03 0,02667015 ! microtubule organizing center organization GO:0031023 39 26 1,000 2,505E-03 0,02655266 GO:0051297|centrosome organization, ! negative regulation of phosphorus metabolic process GO:0010563 51 26 1,000 2,505E-03 0,0264362 GO:0045936|negative regulation of phosphate metabolic process, ! neuron fate commitment GO:0048663 48 27 1,000 2,701E-03 0,02837382 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 1,000 2,701E-03 0,02825046 ! protein amino acid acylation GO:0043543 55 27 1,000 2,701E-03 0,02812816 ! mitochondrial membrane organization GO:0007006 57 27 1,000 2,701E-03 0,02800692 ! primary neural tube formation GO:0014020 51 27 1,000 2,701E-03 0,02788672 ! base-excision repair GO:0006284 41 27 1,000 2,701E-03 0,02776754 ! negative regulation of lymphocyte activation GO:0051250 53 27 1,000 2,701E-03 0,02764938 ! regulation of DNA metabolic process GO:0051052 178 97 2,000 2,731E-03 0,02784686 ! skeletal muscle tissue development GO:0007519 186 99 2,000 2,894E-03 0,02937843 GO:0060538|skeletal muscle organ development, ! dendrite development GO:0016358 59 28 1,000 2,903E-03 0,02934654 ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 2,903E-03 0,02922375 ! regulation of pH GO:0006885 43 29 1,000 3,112E-03 0,03119988 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 1,000 3,112E-03 0,03107042 ! positive regulation of multicellular organism growth GO:0040018 51 30 1,000 3,328E-03 0,03309088 ! ensheathment of neurons GO:0007272 57 30 1,000 3,328E-03 0,0329547 GO:0008366|axon ensheathment, ! negative regulation of leukocyte activation GO:0002695 56 30 1,000 3,328E-03 0,03281964 ! eye morphogenesis GO:0048592 60 30 1,000 3,328E-03 0,03268569 ! regulation of B cell activation GO:0050864 50 30 1,000 3,328E-03 0,03255282 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 1,000 3,551E-03 0,03459289 ! metanephros development GO:0001656 74 32 1,000 3,781E-03 0,03668237 ! response to ionizing radiation GO:0010212 65 32 1,000 3,781E-03 0,03653505 ! regulation of protein import into nucleus GO:0042306 63 32 1,000 3,781E-03 0,03638891 ! peripheral nervous system development GO:0007422 64 32 1,000 3,781E-03 0,03624394 ! positive regulation of catabolic process GO:0009896 64 32 1,000 3,781E-03 0,03610011 ! DNA damage checkpoint GO:0000077 71 33 1,000 4,018E-03 0,03820653 ! positive regulation of gene-specific transcription GO:0043193 65 33 1,000 4,018E-03 0,03805611 ! cell fate specification GO:0001708 52 33 1,000 4,018E-03 0,03790687 ! adult locomotory behavior GO:0008344 59 33 1,000 4,018E-03 0,03775879 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 1,000 4,261E-03 0,03988879 ! regulation of striated muscle tissue development GO:0016202 69 34 1,000 4,261E-03 0,03973418 ! mismatch repair GO:0006298 46 34 1,000 4,261E-03 0,03958076 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 1,000 4,261E-03 0,03942853 ! regulation of muscle development GO:0048634 70 35 1,000 4,511E-03 0,04158097 ! negative regulation of DNA metabolic process GO:0051053 61 35 1,000 4,511E-03 0,04142226 ! odontogenesis GO:0042476 66 35 1,000 4,511E-03 0,04126477 ! embryonic skeletal system morphogenesis GO:0048704 59 35 1,000 4,511E-03 0,04110846 ! telencephalon development GO:0021537 68 35 1,000 4,511E-03 0,04095333 ! calcium-mediated signaling GO:0019722 62 35 1,000 4,511E-03 0,04079937 ! regulation of microtubule-based process GO:0032886 78 35 1,000 4,511E-03 0,04064657 ! neural tube formation GO:0001841 67 35 1,000 4,511E-03 0,0404949 ! positive regulation of JAK-STAT cascade GO:0046427 50 36 1,000 4,767E-03 0,04263867 ! DNA integrity checkpoint GO:0031570 75 36 1,000 4,767E-03 0,04248075 ! embryonic organ development GO:0048568 57 36 1,000 4,767E-03 0,042324 ! negative regulation of cell activation GO:0050866 65 36 1,000 4,767E-03 0,0421684 ! monovalent inorganic cation homeostasis GO:0055067 58 37 1,000 5,03E-03 0,04433273 ! positive regulation of DNA metabolic process GO:0051054 72 38 1,000 5,3E-03 0,04653881 ! mitotic cell cycle checkpoint GO:0007093 76 38 1,000 5,3E-03 0,04636957 ! carbohydrate homeostasis GO:0033500 53 38 1,000 5,3E-03 0,04620157 GO:0042593|glucose homeostasis, ! embryonic epithelial tube formation GO:0001838 72 38 1,000 5,3E-03 0,04603477 ! positive regulation of leukocyte proliferation GO:0070665 62 38 1,000 5,3E-03 0,04586918 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! segmentation GO:0035282 67 39 1,000 5,576E-03 0,0480864 ! regulation of action potential in neuron GO:0019228 73 39 1,000 5,576E-03 0,04791466 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 1,000 5,859E-03 0,05016427 ! multicellular organismal metabolic process GO:0044236 57 40 1,000 5,859E-03 0,04998638 ! cellular amide metabolic process GO:0043603 67 41 1,000 6,148E-03 0,0522675 ! T cell differentiation GO:0030217 81 41 1,000 6,148E-03 0,05208346 ! keratinocyte differentiation GO:0030216 62 41 1,000 6,148E-03 0,05190071 ! regulation of T cell differentiation GO:0045580 70 41 1,000 6,148E-03 0,05171924 ! regulation of T cell proliferation GO:0042129 71 41 1,000 6,148E-03 0,05153903 ! dorsal/ventral pattern formation GO:0009953 68 41 1,000 6,148E-03 0,05136008 ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 6,443E-03 0,05364236 GO:0090047|positive regulation of transcription regulator activity, ! negative regulation of protein complex disassembly GO:0043242 101 42 1,000 6,443E-03 0,05345739 ! regulation of intracellular protein transport GO:0033157 80 42 1,000 6,443E-03 0,05327369 ! neuron migration GO:0001764 79 42 1,000 6,443E-03 0,05309124 ! double-strand break repair GO:0006302 81 44 1,000 7,053E-03 0,05791929 ! B cell differentiation GO:0030183 107 44 1,000 7,053E-03 0,05772228 ! JAK-STAT cascade GO:0007259 71 44 1,000 7,053E-03 0,05752662 ! developmental growth GO:0048589 82 44 1,000 7,053E-03 0,05733227 ! regulation of JAK-STAT cascade GO:0046425 70 45 1,000 7,368E-03 0,05968666 ! branching morphogenesis of a tube GO:0048754 97 45 1,000 7,368E-03 0,05948637 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 1,000 7,689E-03 0,06186808 ! epidermal cell differentiation GO:0009913 68 46 1,000 7,689E-03 0,06166185 ! positive regulation of protein transport GO:0051222 72 46 1,000 7,689E-03 0,061457 ! JNK cascade GO:0007254 91 47 1,000 8,015E-03 0,06385801 ! positive regulation of cell cycle GO:0045787 89 48 1,000 8,349E-03 0,0662922 ! mitochondrial transport GO:0006839 82 48 1,000 8,349E-03 0,06607413 ! morphogenesis of embryonic epithelium GO:0016331 91 48 1,000 8,349E-03 0,0658575 ! activation of caspase activity GO:0006919 84 48 1,000 8,349E-03 0,06564228 ! regulation of lymphocyte differentiation GO:0045619 81 48 1,000 8,349E-03 0,06542846 ! regulation of action potential GO:0001508 95 49 1,000 8,688E-03 0,06786597 ! regulation of protein complex disassembly GO:0043244 113 49 1,000 8,688E-03 0,06764634 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 1,000 8,688E-03 0,06742813 ! endocrine system development GO:0035270 104 49 1,000 8,688E-03 0,06721131 ! neuromuscular process GO:0050905 99 50 1,000 9,033E-03 0,0696589 ! histone modification GO:0016570 91 50 1,000 9,033E-03 0,06943635 ! negative regulation of immune system process GO:0002683 95 50 1,000 9,033E-03 0,06921521 ! embryonic skeletal system development GO:0048706 85 51 1,000 9,384E-03 0,07167944 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 1,000 9,384E-03 0,07145261 ! regulation of angiogenesis GO:0045765 114 52 1,000 9,742E-03 0,07393997 ! covalent chromatin modification GO:0016569 101 52 1,000 9,742E-03 0,07370745 ! morphogenesis of a branching structure GO:0001763 111 52 1,000 9,742E-03 0,07347639 ! synapse organization GO:0050808 85 52 1,000 9,742E-03 0,07324678 ! regulation of neuron apoptosis GO:0043523 100 53 1,000 0,01010529 0,07574245 ! activation of phospholipase C activity GO:0007202 103 54 1,000 0,01047465 0,07826711 GO:0010863|positive regulation of phospholipase C activity, ! negative regulation of cytoskeleton organization GO:0051494 124 54 1,000 0,01047465 0,0780248 ! positive regulation of caspase activity GO:0043280 95 55 1,000 0,01084993 0,08057077 GO:0010952|positive regulation of peptidase activity, ! positive regulation of phospholipase activity GO:0010518 104 55 1,000 0,01084993 0,08032286 ! aging GO:0007568 103 55 1,000 0,01084993 0,08007647 ! heart morphogenesis GO:0003007 97 55 1,000 0,01084993 0,07983159 ! regulation of multicellular organism growth GO:0040014 85 55 1,000 0,01084993 0,0795882 ! skeletal muscle fiber development GO:0048741 111 56 1,000 0,01123109 0,08213374 ! nucleotide-excision repair GO:0006289 83 56 1,000 0,01123109 0,08188485 ! muscle fiber development GO:0048747 112 57 1,000 0,01161809 0,08445056 ! lipid modification GO:0030258 97 57 1,000 0,01161809 0,08419619 ! regulation of phospholipase activity GO:0010517 106 57 1,000 0,01161809 0,08394335 ! regulation of intracellular transport GO:0032386 101 57 1,000 0,01161809 0,08369202 ! adult behavior GO:0030534 99 58 1,000 0,01201091 0,08626343 ! positive regulation of lipase activity GO:0060193 108 58 1,000 0,01201091 0,0860067 ! skeletal system morphogenesis GO:0048705 105 59 1,000 0,0124095 0,08859721 ! camera-type eye development GO:0043010 116 60 1,000 0,01281383 0,09121324 ! kidney development GO:0001822 122 60 1,000 0,01281383 0,09094417 ! viral reproductive process GO:0022415 126 62 1,000 0,01363957 0,09651998 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,01419728 0,10017201 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,01419728 0,09987911 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,01419728 0,09958792 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,01419728 0,09929842 ! neuron fate determination GO:0048664 7 5 0,000 0,01419728 0,0990106 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01419728 0,09872444 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,01419728 0,09843993 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,01419728 0,09815706 ! polyol transport GO:0015791 12 5 0,000 0,01419728 0,0978758 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,01419728 0,09759616 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,01419728 0,09731811 ! response to superoxide GO:0000303 10 5 0,000 0,01419728 0,09704164 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,01419728 0,09676673 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,01419728 0,09649338 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,01419728 0,09622156 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,01419728 0,09595128 ! female meiosis GO:0007143 7 5 0,000 0,01419728 0,09568251 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,01419728 0,09541524 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,01419728 0,09514946 ! cobalt ion transport GO:0006824 11 5 0,000 0,01419728 0,09488515 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,01419728 0,09462231 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,01419728 0,09436093 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,01419728 0,09410098 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,01419728 0,09384246 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,01419728 0,09358536 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,01419728 0,09332966 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,01419728 0,09307536 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,01419728 0,09282243 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,01419728 0,09257088 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,01419728 0,09232069 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01419728 0,09207185 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,01419728 0,09182434 ! negative chemotaxis GO:0050919 14 5 0,000 0,01419728 0,09157816 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,01419728 0,0913333 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,01419728 0,09108975 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,01419728 0,09084749 ! behavioral response to pain GO:0048266 9 5 0,000 0,01419728 0,09060651 ! clathrin coat assembly GO:0048268 14 5 0,000 0,01419728 0,09036681 ! Notch receptor processing GO:0007220 8 5 0,000 0,01419728 0,09012838 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01419728 0,0898912 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,01419728 0,08965526 ! micturition GO:0060073 9 5 0,000 0,01419728 0,08942056 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,01419728 0,08918709 ! copulation GO:0007620 9 5 0,000 0,01419728 0,08895483 ! glial cell fate commitment GO:0021781 13 5 0,000 0,01419728 0,08872378 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,01419728 0,08849393 ! spermidine metabolic process GO:0008216 7 5 0,000 0,01419728 0,08826526 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,01419728 0,08803777 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,01419728 0,08781145 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,01419728 0,0875863 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,01419728 0,08736229 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,01419728 0,08713943 ! grooming behavior GO:0007625 6 5 0,000 0,01419728 0,0869177 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,01419728 0,0866971 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,01419728 0,08647761 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01419728 0,08625923 ! response to protozoan GO:0001562 10 5 0,000 0,01419728 0,08604195 ! lymph vessel development GO:0001945 10 5 0,000 0,01419728 0,08582577 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,01419728 0,08561067 ! endochondral ossification GO:0001958 16 5 0,000 0,01419728 0,08539664 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,01419728 0,08518368 ! anagen GO:0042640 6 5 0,000 0,01419728 0,08497178 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,01419728 0,08476093 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,01419728 0,08455113 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,01419728 0,08434236 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,01419728 0,08413462 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,01419728 0,0839279 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,01419728 0,08372219 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,01419728 0,0835175 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,01419728 0,08331379 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,01419728 0,08311108 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,01419728 0,08290936 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,01419728 0,08270861 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,01419728 0,08250883 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,01419728 0,08231001 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,01419728 0,08211215 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,01419728 0,08191524 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,01419728 0,08171927 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 0,01419728 0,08152424 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,01419728 0,08133013 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,01419728 0,08113695 ! histidine catabolic process GO:0006548 6 5 0,000 0,01419728 0,08094468 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,01419728 0,08075332 ! microvillus organization GO:0032528 7 5 0,000 0,01419728 0,08056287 GO:0030033|microvillus assembly, ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,01419728 0,08037331 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,01419728 0,08018464 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,01419728 0,07999685 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,01419728 0,07980994 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,01419728 0,07962391 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,01419728 0,07943873 ! polyol catabolic process GO:0046174 7 5 0,000 0,01419728 0,07925442 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,01419728 0,07907096 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,01419728 0,07888835 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,01419728 0,07870658 ! muscle cell migration GO:0014812 8 5 0,000 0,01419728 0,07852564 ! mitochondrial fission GO:0000266 8 5 0,000 0,01419728 0,07834554 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,01419728 0,07816626 ! mRNA transcription GO:0009299 9 5 0,000 0,01419728 0,0779878 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,01419728 0,07781015 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,01419728 0,07763331 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,01419728 0,07745727 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,01419728 0,07728203 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,01419728 0,07710757 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,01419728 0,07693391 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,01419728 0,07676102 ! response to food GO:0032094 6 5 0,000 0,01419728 0,07658891 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,01419728 0,07641757 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,01419728 0,076247 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01419728 0,07607718 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,01419728 0,07590812 ! forebrain neuron development GO:0021884 13 5 0,000 0,01419728 0,07573981 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,01419728 0,07557225 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,01419728 0,07540542 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,01419728 0,07523933 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01419728 0,07507397 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,01419728 0,07490933 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,01419728 0,07474542 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01419728 0,07458222 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,01419728 0,07441973 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,01419728 0,07425795 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,01419728 0,07409687 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,01419728 0,07393648 ! basic amino acid transport GO:0015802 11 5 0,000 0,01419728 0,07377679 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,01419728 0,07361779 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,01419728 0,07345947 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01419728 0,07330184 ! depyrimidination GO:0045008 10 5 0,000 0,01419728 0,07314487 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,01419728 0,07298858 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01419728 0,07283295 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,01419728 0,07267799 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,01419728 0,07252368 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 0,01419728 0,07237003 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,01419728 0,07221703 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01419728 0,07206467 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,01419728 0,07191296 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,01419728 0,07176188 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,01419728 0,07161144 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,01419728 0,07146162 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,01419728 0,07131243 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01419728 0,07116387 ! response to arsenic GO:0046685 10 5 0,000 0,01419728 0,07101592 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,01419728 0,07086858 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,01419728 0,07072185 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,01419728 0,07057573 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,01419728 0,07043022 ! response to cadmium ion GO:0046686 7 5 0,000 0,01419728 0,0702853 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,01419728 0,07014098 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,01419728 0,06999724 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,01419728 0,0698541 ! decidualization GO:0046697 11 5 0,000 0,01419728 0,06971154 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,01419728 0,06956956 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,01419728 0,06942816 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,01419728 0,06928733 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,01419728 0,06914708 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,01419728 0,06900738 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,01419728 0,06886826 ! neural tube patterning GO:0021532 7 5 0,000 0,01419728 0,06872969 ! embryonic cleavage GO:0040016 6 5 0,000 0,01419728 0,06859168 ! peroxisome fission GO:0016559 5 5 0,000 0,01419728 0,06845422 ! histone demethylation GO:0016577 10 5 0,000 0,01419728 0,06831731 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,01419728 0,06818095 ! mitotic recombination GO:0006312 9 5 0,000 0,01419728 0,06804513 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,01419728 0,06790985 ! metaphase plate congression GO:0051310 7 5 0,000 0,01419728 0,06777511 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01419728 0,0676409 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,01419728 0,06750722 ! enteric nervous system development GO:0048484 8 5 0,000 0,01419728 0,06737407 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,01419728 0,06724145 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,01419728 0,06710934 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,01419728 0,06697776 ! muscle cell proliferation GO:0033002 11 5 0,000 0,01419728 0,06684668 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,01419728 0,06671612 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,01419728 0,06658607 ! plasminogen activation GO:0031639 5 5 0,000 0,01419728 0,06645653 ! B cell homeostasis GO:0001782 13 5 0,000 0,01419728 0,06632749 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,01419728 0,06619894 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,01419728 0,0660709 ! metaphase GO:0051323 8 5 0,000 0,01419728 0,06594335 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,01419728 0,06581629 ! cellular response to nutrient GO:0031670 8 5 0,000 0,01419728 0,06568972 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,01419728 0,06556364 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,01419728 0,06543804 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,01419728 0,06531292 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,01419728 0,06518827 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,01419728 0,06506411 ! response to redox state GO:0051775 5 5 0,000 0,01419728 0,06494041 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,01419728 0,06481718 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,01419728 0,06469442 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,01419728 0,06457213 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,01419728 0,06445029 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01419728 0,06432892 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,01419728 0,064208 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01419728 0,06408753 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,01419728 0,06396752 ! striatum development GO:0021756 9 5 0,000 0,01419728 0,06384795 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,01419728 0,06372883 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,01419728 0,06361016 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,01419728 0,06349192 ! glial cell migration GO:0008347 11 5 0,000 0,01419728 0,06337413 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,01419728 0,06325677 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,01419728 0,06313984 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,01419728 0,06302335 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,01419728 0,06290728 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,01419728 0,06279165 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,01419728 0,06267643 ! neuroprotection GO:0043526 6 5 0,000 0,01419728 0,06256164 ! neural plate development GO:0001840 8 5 0,000 0,01419728 0,06244727 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,01419728 0,06233331 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,01419728 0,06221977 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,01419728 0,06210665 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,01419728 0,06199393 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,01419728 0,06188162 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,01419728 0,06176972 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,01419728 0,06165822 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,01419728 0,06154713 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,01419728 0,06143643 ! spindle assembly GO:0051225 6 5 0,000 0,01419728 0,06132613 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,01419728 0,06121623 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,01419728 0,06110672 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,01419728 0,0609976 ! drug metabolic process GO:0017144 6 5 0,000 0,01419728 0,06088887 ! stem cell division GO:0017145 11 5 0,000 0,01419728 0,06078053 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,01419728 0,06067257 ! organ regeneration GO:0031100 7 5 0,000 0,01419728 0,06056499 ! carnitine metabolic process GO:0009437 7 5 0,000 0,01419728 0,0604578 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,01419728 0,06035098 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,01419728 0,06024454 ! viral reproduction GO:0016032 134 68 1,000 0,01625088 0,06883735 ! regulation of lipase activity GO:0060191 130 68 1,000 0,01625088 0,06871637 ! cell cycle checkpoint GO:0000075 137 69 1,000 0,01670529 0,07051392 ! urogenital system development GO:0001655 137 69 1,000 0,01670529 0,07039043 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,01701274 0,07156057 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,01701274 0,07143568 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,01701274 0,07131123 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,01701274 0,07118721 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,01701274 0,07106362 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,01701274 0,07094046 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,01701274 0,07081772 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,01701274 0,07069541 ! sleep GO:0030431 13 6 0,000 0,01701274 0,07057352 ! response to oxygen radical GO:0000305 11 6 0,000 0,01701274 0,07045206 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,01701274 0,070331 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,01701274 0,07021037 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,01701274 0,07009014 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,01701274 0,06997033 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,01701274 0,06985093 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,01701274 0,06973193 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,01701274 0,06961334 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,01701274 0,06949515 ! male meiosis GO:0007140 7 6 0,000 0,01701274 0,06937736 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,01701274 0,06925997 ! response to zinc ion GO:0010043 9 6 0,000 0,01701274 0,06914298 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,01701274 0,06902638 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,01701274 0,06891018 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,01701274 0,06879436 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,01701274 0,06867893 ! malate metabolic process GO:0006108 11 6 0,000 0,01701274 0,06856389 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,01701274 0,06844924 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,01701274 0,06833497 ! protein refolding GO:0042026 15 6 0,000 0,01701274 0,06822107 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,01701274 0,06810756 ! opsonization GO:0008228 8 6 0,000 0,01701274 0,06799443 ! mating behavior GO:0007617 7 6 0,000 0,01701274 0,06788167 ! neuron remodeling GO:0016322 15 6 0,000 0,01701274 0,06776928 ! erythrocyte maturation GO:0043249 7 6 0,000 0,01701274 0,06765726 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,01701274 0,06754562 ! equilibrioception GO:0050957 14 6 0,000 0,01701274 0,06743434 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,01701274 0,06732343 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,01701274 0,06721288 ! photoreceptor cell development GO:0042461 10 6 0,000 0,01701274 0,0671027 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,01701274 0,06699287 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,01701274 0,06688341 ! response to interferon-gamma GO:0034341 15 6 0,000 0,01701274 0,0667743 ! toxin metabolic process GO:0009404 11 6 0,000 0,01701274 0,06666554 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,01701274 0,06655715 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,01701274 0,0664491 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,01701274 0,0663414 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,01701274 0,06623405 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,01701274 0,06612705 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,01701274 0,06602039 ! thymic T cell selection GO:0045061 12 6 0,000 0,01701274 0,06591408 ! protein lipoylation GO:0009249 10 6 0,000 0,01701274 0,06580811 ! cysteine metabolic process GO:0006534 10 6 0,000 0,01701274 0,06570248 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,01701274 0,06559719 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,01701274 0,06549223 ! glutamate catabolic process GO:0006538 10 6 0,000 0,01701274 0,06538761 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,01701274 0,06528332 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,01701274 0,06517937 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,01701274 0,06507575 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,01701274 0,06497245 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,01701274 0,06486948 ! hyperosmotic response GO:0006972 9 6 0,000 0,01701274 0,06476684 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,01701274 0,06466453 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,01701274 0,06456253 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,01701274 0,06446086 ! urea metabolic process GO:0019627 7 6 0,000 0,01701274 0,0643595 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,01701274 0,06425847 ! neutrophil activation GO:0042119 8 6 0,000 0,01701274 0,06415775 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,01701274 0,06405735 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,01701274 0,06395726 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,01701274 0,06385748 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,01701274 0,06375801 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,01701274 0,06365886 ! neuron apoptosis GO:0051402 9 6 0,000 0,01701274 0,06356001 ! nucleoside salvage GO:0043174 9 6 0,000 0,01701274 0,06346146 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,01701274 0,06336323 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,01701274 0,06326529 ! T cell mediated immunity GO:0002456 16 6 0,000 0,01701274 0,06316766 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,01701274 0,06307033 GO:0010543|regulation of platelet activation, ! carnitine transport GO:0015879 10 6 0,000 0,01701274 0,0629733 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,01701274 0,06287657 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01701274 0,06278013 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,01701274 0,06268399 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,01701274 0,06258814 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,01701274 0,06249259 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,01701274 0,06239732 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,01701274 0,06230235 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,01701274 0,06220767 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,01701274 0,06211327 ! establishment of spindle localization GO:0051293 12 6 0,000 0,01701274 0,06201916 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,01701274 0,06192533 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,01701274 0,06183179 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,01701274 0,06173853 ! neural nucleus development GO:0048857 14 6 0,000 0,01701274 0,06164555 ! response to UV-C GO:0010225 11 6 0,000 0,01701274 0,06155285 ! astrocyte development GO:0014002 15 6 0,000 0,01701274 0,06146043 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,01701274 0,06136828 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,01701274 0,06127641 ! interaction with symbiont GO:0051702 13 6 0,000 0,01701274 0,06118482 ! regulation of dendrite development GO:0050773 16 6 0,000 0,01701274 0,0610935 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,01701274 0,06100245 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,01701274 0,06091167 ! response to copper ion GO:0046688 10 6 0,000 0,01701274 0,06082117 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,01701274 0,06073093 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,01701274 0,06064095 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01701274 0,06055125 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,01701274 0,06046181 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,01701274 0,06037263 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,01701274 0,06028372 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,01701274 0,06019507 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,01701274 0,06010667 ! hair follicle maturation GO:0048820 7 6 0,000 0,01701274 0,06001854 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,01701274 0,05993067 ! Schwann cell development GO:0014044 15 6 0,000 0,01701274 0,05984305 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,01701274 0,05975569 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,01701274 0,05966858 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,01701274 0,05958172 ! subpallium development GO:0021544 10 6 0,000 0,01701274 0,05949512 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,01701274 0,05940877 ! histone ubiquitination GO:0016574 8 6 0,000 0,01701274 0,05932267 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,01701274 0,05923682 ! maintenance of organ identity GO:0048496 9 6 0,000 0,01701274 0,05915122 ! G2 phase GO:0051319 16 6 0,000 0,01701274 0,05906587 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,01701274 0,05898076 ! establishment of planar polarity GO:0001736 7 6 0,000 0,01701274 0,05889589 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,01701274 0,05881127 ! membrane to membrane docking GO:0022614 14 6 0,000 0,01701274 0,05872689 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,01701274 0,05864276 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,01701274 0,05855886 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,01701274 0,05847521 ! receptor internalization GO:0031623 10 6 0,000 0,01701274 0,05839179 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,01701274 0,05830861 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,01701274 0,05822567 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01701274 0,05814296 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,01701274 0,05806049 ! protein deubiquitination GO:0016579 14 6 0,000 0,01701274 0,05797825 ! protein destabilization GO:0031648 9 6 0,000 0,01701274 0,05789624 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,01701274 0,05781447 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,01701274 0,05773293 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,01701274 0,05765161 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,01701274 0,05757053 ! progesterone metabolic process GO:0042448 10 6 0,000 0,01701274 0,05748967 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,01701274 0,05740904 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,01701274 0,05732863 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,01701274 0,05724845 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,01701274 0,0571685 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,01701274 0,05708876 ! determination of adult lifespan GO:0008340 15 6 0,000 0,01701274 0,05700925 ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,01701274 0,05692996 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,01701274 0,0568509 ! catecholamine transport GO:0051937 9 6 0,000 0,01701274 0,05677205 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,01701274 0,05669341 ! sensory cilium assembly GO:0035058 10 6 0,000 0,01701274 0,056615 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,01701274 0,0565368 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,01701274 0,05645882 ! maternal placenta development GO:0001893 12 6 0,000 0,01701274 0,05638105 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,01701274 0,0563035 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,01701274 0,05622616 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,01701274 0,05614903 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,01701274 0,05607212 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,01701274 0,05599541 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,01701274 0,05591891 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,01701274 0,05584263 ! B cell activation GO:0042113 160 71 1,000 0,01763027 0,05779077 ! phosphoinositide metabolic process GO:0030384 128 72 1,000 0,01810076 0,05925229 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 1,000 0,01810076 0,05917179 ! axon guidance GO:0007411 139 73 1,000 0,01857655 0,06064475 ! regulation of transcription factor activity GO:0051090 126 74 1,000 0,0190576 0,06213086 GO:0090046|regulation of transcription regulator activity, ! eye development GO:0001654 143 74 1,000 0,0190576 0,06204679 ! phosphoinositide-mediated signaling GO:0048015 131 75 1,000 0,01954387 0,06354398 ! lymphocyte differentiation GO:0030098 167 75 1,000 0,01954387 0,06345823 ! tRNA transcription GO:0009304 14 7 0,000 0,01982025 0,06426888 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,01982025 0,06418238 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,01982025 0,06409612 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,01982025 0,06401008 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,01982025 0,06392428 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,01982025 0,0638387 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,01982025 0,06375336 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,01982025 0,06366824 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,01982025 0,06358335 ! prostate gland development GO:0030850 13 7 0,000 0,01982025 0,06349868 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,01982025 0,06341424 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,01982025 0,06333003 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,01982025 0,06324604 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,01982025 0,06316227 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01982025 0,06307872 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,01982025 0,06299539 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,01982025 0,06291228 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 0,01982025 0,0628294 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,01982025 0,06274673 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,01982025 0,06266427 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,01982025 0,06258204 ! glycolipid transport GO:0046836 10 7 0,000 0,01982025 0,06250001 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,01982025 0,06241821 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,01982025 0,06233662 ! neuron adhesion GO:0007158 12 7 0,000 0,01982025 0,06225524 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,01982025 0,06217407 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,01982025 0,06209311 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,01982025 0,06201237 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,01982025 0,06193183 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,01982025 0,06185151 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,01982025 0,06177139 ! mRNA stabilization GO:0048255 18 7 0,000 0,01982025 0,06169148 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,01982025 0,06161177 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,01982025 0,06153227 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,01982025 0,06145298 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,01982025 0,06137389 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,01982025 0,061295 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,01982025 0,06121632 ! lipoprotein transport GO:0042953 14 7 0,000 0,01982025 0,06113783 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,01982025 0,06105955 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,01982025 0,06098147 ! rhythmic behavior GO:0007622 15 7 0,000 0,01982025 0,06090359 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,01982025 0,06082591 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,01982025 0,06074842 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,01982025 0,06067113 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,01982025 0,06059404 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,01982025 0,06051715 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,01982025 0,06044045 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,01982025 0,06036394 ! mechanosensory behavior GO:0007638 14 7 0,000 0,01982025 0,06028762 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,01982025 0,0602115 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,01982025 0,06013558 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,01982025 0,06005984 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01982025 0,05998429 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,01982025 0,05990893 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,01982025 0,05983377 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,01982025 0,05975879 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,01982025 0,05968399 ! adrenal gland development GO:0030325 17 7 0,000 0,01982025 0,05960939 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,01982025 0,05953497 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,01982025 0,05946074 ! ovulation GO:0030728 9 7 0,000 0,01982025 0,05938669 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,01982025 0,05931282 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,01982025 0,05923914 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,01982025 0,05916565 ! microtubule nucleation GO:0007020 20 7 0,000 0,01982025 0,05909233 ! proline biosynthetic process GO:0006561 10 7 0,000 0,01982025 0,0590192 ! thyroid hormone generation GO:0006590 13 7 0,000 0,01982025 0,05894624 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,01982025 0,05887347 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,01982025 0,05880088 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,01982025 0,05872846 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,01982025 0,05865623 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,01982025 0,05858417 ! galactose metabolic process GO:0006012 13 7 0,000 0,01982025 0,05851228 ! vesicle fusion GO:0006906 17 7 0,000 0,01982025 0,05844058 ! response to dietary excess GO:0002021 8 7 0,000 0,01982025 0,05836905 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,01982025 0,05829769 ! intracellular pH reduction GO:0051452 11 7 0,000 0,01982025 0,05822651 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,01982025 0,0581555 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,01982025 0,05808467 ! organ growth GO:0035265 15 7 0,000 0,01982025 0,058014 ! purine salvage GO:0043101 10 7 0,000 0,01982025 0,05794351 ! nucleoside transport GO:0015858 8 7 0,000 0,01982025 0,05787319 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,01982025 0,05780304 ! parturition GO:0007567 14 7 0,000 0,01982025 0,05773306 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,01982025 0,05766325 ! rRNA modification GO:0000154 14 7 0,000 0,01982025 0,05759361 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,01982025 0,05752414 ! spindle checkpoint GO:0031577 15 7 0,000 0,01982025 0,05745483 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,01982025 0,05738569 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,01982025 0,05731672 ! macrophage differentiation GO:0030225 11 7 0,000 0,01982025 0,05724791 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,01982025 0,05717927 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,01982025 0,05711079 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,01982025 0,05704248 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,01982025 0,05697433 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,01982025 0,05690634 ! fibrinolysis GO:0042730 10 7 0,000 0,01982025 0,05683851 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,01982025 0,05677085 ! eating behavior GO:0042755 7 7 0,000 0,01982025 0,05670334 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,01982025 0,056636 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,01982025 0,05656882 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,01982025 0,05650179 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,01982025 0,05643492 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,01982025 0,05636822 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,01982025 0,05630167 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,01982025 0,05623527 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,01982025 0,05616904 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,01982025 0,05610295 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,01982025 0,05603703 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,01982025 0,05597126 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,01982025 0,05590564 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,01982025 0,05584018 ! regulation of meiosis GO:0040020 12 7 0,000 0,01982025 0,05577487 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,01982025 0,05570971 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,01982025 0,0556447 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,01982025 0,05557985 ! oxygen homeostasis GO:0032364 12 7 0,000 0,01982025 0,05551515 ! transcription termination GO:0006353 13 7 0,000 0,01982025 0,05545059 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,01982025 0,05538619 ! anaphase GO:0051322 17 7 0,000 0,01982025 0,05532194 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,01982025 0,05525783 ! axonal fasciculation GO:0007413 18 7 0,000 0,01982025 0,05519388 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,01982025 0,05513007 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,01982025 0,05506641 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,01982025 0,0550029 ! diuresis GO:0030146 12 7 0,000 0,01982025 0,05493953 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,01982025 0,05487631 ! thiamin metabolic process GO:0006772 7 7 0,000 0,01982025 0,05481323 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,01982025 0,0547503 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,01982025 0,05468751 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,01982025 0,05462487 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,01982025 0,05456237 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,01982025 0,05450001 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,01982025 0,0544378 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,01982025 0,05437573 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,01982025 0,05431379 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,01982025 0,054252 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,01982025 0,05419035 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,01982025 0,05412884 ! lymph node development GO:0048535 10 7 0,000 0,01982025 0,05406747 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,01982025 0,05400624 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,01982025 0,05394515 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,01982025 0,05388419 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,01982025 0,05382338 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,01982025 0,0537627 ! adult feeding behavior GO:0008343 9 7 0,000 0,01982025 0,05370215 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,01982025 0,05364174 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,01982025 0,05358147 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,01982025 0,05352134 ! muscle adaptation GO:0043500 14 7 0,000 0,01982025 0,05346134 ! embryonic heart tube development GO:0035050 10 7 0,000 0,01982025 0,05340147 ! retina homeostasis GO:0001895 12 7 0,000 0,01982025 0,05334174 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,01982025 0,05328214 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,01982025 0,05322267 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,01982025 0,05316333 ! protein prenylation GO:0018342 18 7 0,000 0,01982025 0,05310413 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,01982025 0,05304506 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,01982025 0,05298612 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,01982025 0,05292732 ! regulation of catabolic process GO:0009894 161 76 1,000 0,02003533 0,05344236 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 0,02053196 0,05470642 ! negative regulation of organelle organization GO:0010639 161 78 1,000 0,02103371 0,05598132 ! T cell activation GO:0042110 168 81 1,000 0,02256941 0,06000222 ! response to hypoxia GO:0001666 171 81 1,000 0,02256941 0,05993599 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,02261983 0,06000365 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,02261983 0,05993757 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,02261983 0,05987163 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,02261983 0,05980583 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,02261983 0,05974019 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,02261983 0,05967468 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,02261983 0,05960932 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,02261983 0,0595441 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,02261983 0,05947903 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,02261983 0,05941409 ! meiotic prophase I GO:0007128 13 8 0,000 0,02261983 0,0593493 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,02261983 0,05928465 ! oligopeptide transport GO:0006857 15 8 0,000 0,02261983 0,05922014 ! UTP metabolic process GO:0046051 8 8 0,000 0,02261983 0,05915577 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,02261983 0,05909154 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,02261983 0,05902745 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,02261983 0,0589635 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,02261983 0,05889969 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,02261983 0,05883601 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,02261983 0,05877247 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,02261983 0,05870907 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,02261983 0,05864581 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,02261983 0,05858268 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,02261983 0,05851969 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,02261983 0,05845683 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,02261983 0,05839411 ! reflex GO:0060004 16 8 0,000 0,02261983 0,05833152 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,02261983 0,05826907 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,02261983 0,05820675 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,02261983 0,05814456 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,02261983 0,05808251 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,02261983 0,05802059 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,02261983 0,0579588 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,02261983 0,05789714 ! pigment granule organization GO:0048753 16 8 0,000 0,02261983 0,05783561 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,02261983 0,05777421 ! astrocyte differentiation GO:0048708 18 8 0,000 0,02261983 0,05771295 ! histidine metabolic process GO:0006547 16 8 0,000 0,02261983 0,05765181 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,02261983 0,0575908 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,02261983 0,05752993 ! glycine catabolic process GO:0006546 13 8 0,000 0,02261983 0,05746918 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,02261983 0,05740855 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,02261983 0,05734806 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,02261983 0,05728769 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,02261983 0,05722745 ! melanin metabolic process GO:0006582 15 8 0,000 0,02261983 0,05716734 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,02261983 0,05710735 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,02261983 0,05704749 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,02261983 0,05698776 ! macrophage activation GO:0042116 12 8 0,000 0,02261983 0,05692815 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,02261983 0,05686866 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,02261983 0,0568093 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,02261983 0,05675006 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,02261983 0,05669095 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,02261983 0,05663196 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,02261983 0,05657309 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,02261983 0,05651434 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,02261983 0,05645571 ! osteoblast development GO:0002076 16 8 0,000 0,02261983 0,05639721 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,02261983 0,05633883 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,02261983 0,05628057 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,02261983 0,05622243 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,02261983 0,05616441 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,02261983 0,0561065 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,02261983 0,05604872 ! response to UV-B GO:0010224 16 8 0,000 0,02261983 0,05599106 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,02261983 0,05593351 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,02261983 0,05587609 ! intermediate filament organization GO:0045109 12 8 0,000 0,02261983 0,05581878 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,02261983 0,05576159 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,02261983 0,05570451 ! cellular extravasation GO:0045123 12 8 0,000 0,02261983 0,05564756 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,02261983 0,05559071 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,02261983 0,05553399 ! response to antibiotic GO:0046677 11 8 0,000 0,02261983 0,05547738 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,02261983 0,05542089 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,02261983 0,05536451 ! DNA topological change GO:0006265 12 8 0,000 0,02261983 0,05530824 ! response to tropane GO:0014073 15 8 0,000 0,02261983 0,05525209 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,02261983 0,05519605 ! melanosome transport GO:0032402 13 8 0,000 0,02261983 0,05514013 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,02261983 0,05508432 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,02261983 0,05502862 ! mast cell activation GO:0045576 14 8 0,000 0,02261983 0,05497304 ! multicellular organismal aging GO:0010259 18 8 0,000 0,02261983 0,05491757 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,02261983 0,05486221 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,02261983 0,05480696 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,02261983 0,05475182 ! nucleosome disassembly GO:0006337 14 8 0,000 0,02261983 0,05469679 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,02261983 0,05464188 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,02261983 0,05458707 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,02261983 0,05453237 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,02261983 0,05447779 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,02261983 0,05442331 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,02261983 0,05436894 ! intracellular lipid transport GO:0032365 13 8 0,000 0,02261983 0,05431468 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,02261983 0,05426053 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,02261983 0,05420648 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,02261983 0,05415255 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,02261983 0,05409872 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,02261983 0,05404499 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,02261983 0,05399138 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,02261983 0,05393787 ! hormone catabolic process GO:0042447 17 8 0,000 0,02261983 0,05388446 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,02261983 0,05383117 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,02261983 0,05377797 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,02261983 0,05372489 ! ATP catabolic process GO:0006200 11 8 0,000 0,02261983 0,0536719 ! blastocyst growth GO:0001832 19 8 0,000 0,02261983 0,05361902 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,02261983 0,05356625 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,02261983 0,05351358 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,02261983 0,05346101 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,02261983 0,05340855 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,02261983 0,05335619 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,02261983 0,05330393 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,02261983 0,05325177 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,02261983 0,05319972 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,02261983 0,05314776 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,02261983 0,05309591 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,02261983 0,05304416 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,02261983 0,05299251 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,02261983 0,05294096 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,02261983 0,05288951 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,02261983 0,05283816 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,02261983 0,05278691 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,02261983 0,05273576 ! response to drug GO:0042493 143 82 1,000 0,02309135 0,05378296 ! response to oxygen levels GO:0070482 176 83 1,000 0,02361826 0,05495699 ! positive regulation of cell activation GO:0050867 145 85 1,000 0,02468684 0,05738795 GO:0002696|positive regulation of leukocyte activation, ! axon extension GO:0048675 15 9 0,000 0,02541151 0,05901553 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,02541151 0,05895862 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,02541151 0,05890182 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,02541151 0,05884513 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,02541151 0,05878855 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,02541151 0,05873208 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,02541151 0,05867571 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,02541151 0,05861945 ! phosphate transport GO:0006817 19 9 0,000 0,02541151 0,05856331 ! reproductive behavior GO:0019098 19 9 0,000 0,02541151 0,05850726 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,02541151 0,05845133 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,02541151 0,0583955 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,02541151 0,05833978 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,02541151 0,05828417 ! GTP metabolic process GO:0046039 9 9 0,000 0,02541151 0,05822866 ! RNA methylation GO:0001510 15 9 0,000 0,02541151 0,05817326 ! elastic fiber assembly GO:0048251 15 9 0,000 0,02541151 0,05811796 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,02541151 0,05806276 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,02541151 0,05800768 ! artery development GO:0060840 24 9 0,000 0,02541151 0,05795269 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,02541151 0,05789781 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,02541151 0,05784304 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,02541151 0,05778837 ! chemosensory behavior GO:0007635 20 9 0,000 0,02541151 0,0577338 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,02541151 0,05767933 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,02541151 0,05762497 ! leukocyte degranulation GO:0043299 16 9 0,000 0,02541151 0,05757071 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,02541151 0,05751655 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,02541151 0,05746249 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,02541151 0,05740854 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,02541151 0,05735468 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,02541151 0,05730093 ! protein targeting to ER GO:0045047 22 9 0,000 0,02541151 0,05724728 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,02541151 0,05719372 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,02541151 0,05714027 ! T cell selection GO:0045058 23 9 0,000 0,02541151 0,05708692 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,02541151 0,05703367 ! endosome organization GO:0007032 17 9 0,000 0,02541151 0,05698051 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,02541151 0,05692746 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,02541151 0,0568745 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,02541151 0,05682165 ! mannose metabolic process GO:0006013 13 9 0,000 0,02541151 0,05676889 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,02541151 0,05671623 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,02541151 0,05666366 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,02541151 0,0566112 ! receptor clustering GO:0043113 18 9 0,000 0,02541151 0,05655883 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,02541151 0,05650655 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,02541151 0,05645438 ! ruffle organization GO:0031529 15 9 0,000 0,02541151 0,0564023 ! retinol metabolic process GO:0042572 18 9 0,000 0,02541151 0,05635031 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,02541151 0,05629843 ! behavioral fear response GO:0001662 22 9 0,000 0,02541151 0,05624663 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,02541151 0,05619494 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,02541151 0,05614333 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,02541151 0,05609183 GO:0030204|chondroitin sulfate metabolic process, ! oligodendrocyte development GO:0014003 10 9 0,000 0,02541151 0,05604041 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,02541151 0,05598909 ! segment specification GO:0007379 13 9 0,000 0,02541151 0,05593787 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,02541151 0,05588674 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,02541151 0,0558357 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,02541151 0,05578475 ! response to amine stimulus GO:0014075 13 9 0,000 0,02541151 0,0557339 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,02541151 0,05568314 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,02541151 0,05563248 ! erythrocyte development GO:0048821 15 9 0,000 0,02541151 0,0555819 ! gas homeostasis GO:0033483 16 9 0,000 0,02541151 0,05553142 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,02541151 0,05548103 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,02541151 0,05543073 ! renal water homeostasis GO:0003091 14 9 0,000 0,02541151 0,05538052 ! postreplication repair GO:0006301 22 9 0,000 0,02541151 0,0553304 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,02541151 0,05528037 ! icosanoid secretion GO:0032309 15 9 0,000 0,02541151 0,05523043 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,02541151 0,05518059 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,02541151 0,05513083 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,02541151 0,05508116 ! regulation of cell division GO:0051302 15 9 0,000 0,02541151 0,05503159 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,02541151 0,0549821 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,02541151 0,0549327 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,02541151 0,05488339 ! sterol catabolic process GO:0016127 11 9 0,000 0,02541151 0,05483416 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,02541151 0,05478503 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,02541151 0,05473598 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,02541151 0,05468702 GO:0002820|negative regulation of adaptive immune response, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,02541151 0,05463815 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,02541151 0,05458937 ! musculoskeletal movement GO:0050881 14 9 0,000 0,02541151 0,05454067 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,02541151 0,05449206 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,02541151 0,05444354 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,02541151 0,0543951 ! purine base metabolic process GO:0006144 21 9 0,000 0,02541151 0,05434675 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,02541151 0,05429848 ! pigment granule transport GO:0051904 17 9 0,000 0,02541151 0,0542503 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,02541151 0,05420221 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,02541151 0,0541542 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,02541151 0,05410628 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,02541151 0,05405844 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,02541151 0,05401068 ! mitochondrion localization GO:0051646 15 9 0,000 0,02541151 0,05396301 ! regulation of protein transport GO:0051223 154 87 1,000 0,0257749 0,05468643 GO:0070201|regulation of establishment of protein localization, ! positive regulation of protein modification process GO:0031401 136 88 1,000 0,02632616 0,05580682 ! regulation of neurological system process GO:0031644 148 88 1,000 0,02632616 0,05575769 ! regulation of cell adhesion GO:0030155 212 89 1,000 0,02688219 0,05688528 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,02819531 0,05961152 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,02819531 0,05955918 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,02819531 0,05950694 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,02819531 0,05945479 ! synapsis GO:0007129 13 10 0,000 0,02819531 0,05940272 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,02819531 0,05935075 ! N-glycan processing GO:0006491 20 10 0,000 0,02819531 0,05929887 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,02819531 0,05924708 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,02819531 0,05919538 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,02819531 0,05914378 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,02819531 0,05909226 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,02819531 0,05904083 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 0,02819531 0,05898949 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,02819531 0,05893824 GO:0048200|Golgi transport vesicle coating, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,02819531 0,05888708 ! androgen metabolic process GO:0008209 17 10 0,000 0,02819531 0,058836 ! phospholipid efflux GO:0033700 16 10 0,000 0,02819531 0,05878502 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,02819531 0,05873412 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,02819531 0,05868331 ! lung alveolus development GO:0048286 26 10 0,000 0,02819531 0,05863259 ! pathogenesis GO:0009405 13 10 0,000 0,02819531 0,05858196 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,02819531 0,05853142 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,02819531 0,05848096 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,02819531 0,05843059 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,02819531 0,0583803 ! endoderm development GO:0007492 16 10 0,000 0,02819531 0,0583301 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,02819531 0,05827999 ! arginine catabolic process GO:0006527 13 10 0,000 0,02819531 0,05822997 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,02819531 0,05818003 ! proline metabolic process GO:0006560 13 10 0,000 0,02819531 0,05813017 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,02819531 0,0580804 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,02819531 0,05803072 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,02819531 0,05798112 ! V(D)J recombination GO:0033151 28 10 0,000 0,02819531 0,05793161 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,02819531 0,05788218 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,02819531 0,05783283 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,02819531 0,05778357 ! B cell proliferation GO:0042100 18 10 0,000 0,02819531 0,05773439 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,02819531 0,0576853 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,02819531 0,05763629 ! multicellular organism growth GO:0035264 18 10 0,000 0,02819531 0,05758736 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,02819531 0,05753852 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,02819531 0,05748976 ! epithelial cell development GO:0002064 20 10 0,000 0,02819531 0,05744108 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,02819531 0,05739248 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,02819531 0,05734397 ! macroautophagy GO:0016236 17 10 0,000 0,02819531 0,05729553 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,02819531 0,05724718 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,02819531 0,05719891 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,02819531 0,05715073 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,02819531 0,05710262 ! copper ion homeostasis GO:0055070 13 10 0,000 0,02819531 0,05705459 ! regulation of bone resorption GO:0045124 25 10 0,000 0,02819531 0,05700665 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,02819531 0,05695878 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,02819531 0,056911 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,02819531 0,05686329 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,02819531 0,05681567 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,02819531 0,05676813 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,02819531 0,05672066 ! blastoderm segmentation GO:0007350 18 10 0,000 0,02819531 0,05667328 ! response to dsRNA GO:0043331 20 10 0,000 0,02819531 0,05662597 ! DNA ligation GO:0006266 19 10 0,000 0,02819531 0,05657874 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,02819531 0,05653159 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,02819531 0,05648452 ! melanosome localization GO:0032400 16 10 0,000 0,02819531 0,05643753 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,02819531 0,05639062 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,02819531 0,05634378 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,02819531 0,05629702 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,02819531 0,05625034 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,02819531 0,05620374 ! mRNA cleavage GO:0006379 17 10 0,000 0,02819531 0,05615721 ! protein sumoylation GO:0016925 15 10 0,000 0,02819531 0,05611076 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,02819531 0,05606439 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,02819531 0,05601809 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,02819531 0,05597187 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,02819531 0,05592573 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,02819531 0,05587966 ! salivary gland development GO:0007431 27 10 0,000 0,02819531 0,05583367 ! prophase GO:0051324 15 10 0,000 0,02819531 0,05578776 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,02819531 0,05574192 ! apical protein localization GO:0045176 15 10 0,000 0,02819531 0,05569615 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,02819531 0,05565046 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,02819531 0,05560485 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,02819531 0,0555593 ! midbrain development GO:0030901 13 10 0,000 0,02819531 0,05551384 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,02819531 0,05546845 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,02819531 0,05542313 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,02819531 0,05537789 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,02819531 0,05533272 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,02819531 0,05528762 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,02819531 0,0552426 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,02819531 0,05519765 ! detection of calcium ion GO:0005513 23 10 0,000 0,02819531 0,05515277 ! oocyte development GO:0048599 17 10 0,000 0,02819531 0,05510797 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,02819531 0,05506324 ! blastocyst formation GO:0001825 17 10 0,000 0,02819531 0,05501858 ! cerebellar cortex development GO:0021695 15 10 0,000 0,02819531 0,054974 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,02819531 0,05492948 ! activation of innate immune response GO:0002218 12 10 0,000 0,02819531 0,05488504 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,02819531 0,05484067 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,02819531 0,05479637 ! response to nicotine GO:0035094 20 10 0,000 0,02819531 0,05475215 ! establishment of cell polarity GO:0030010 16 10 0,000 0,02819531 0,05470799 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,02819531 0,05466391 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,02819531 0,0546199 ! regulation of membrane potential GO:0042391 164 93 1,000 0,02915348 0,05643063 ! regulation of T cell activation GO:0050863 158 94 1,000 0,02973294 0,05750599 ! forebrain development GO:0030900 188 95 1,000 0,03031698 0,05858848 ! leukocyte differentiation GO:0002521 202 96 1,000 0,03090559 0,05967805 ! respiratory burst GO:0045730 17 11 0,000 0,03097125 0,05975687 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,03097125 0,05970899 ! telencephalon cell migration GO:0022029 20 11 0,000 0,03097125 0,05966119 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,03097125 0,05961346 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,03097125 0,0595658 ! thyroid gland development GO:0030878 26 11 0,000 0,03097125 0,05951823 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,03097125 0,05947073 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,03097125 0,0594233 ! response to pain GO:0048265 24 11 0,000 0,03097125 0,05937595 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,03097125 0,05932868 ! T cell proliferation GO:0042098 26 11 0,000 0,03097125 0,05928148 ! blood vessel remodeling GO:0001974 29 11 0,000 0,03097125 0,05923436 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,03097125 0,05918731 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,03097125 0,05914033 ! bone resorption GO:0045453 16 11 0,000 0,03097125 0,05909343 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,03097125 0,05904661 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,03097125 0,05899986 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,03097125 0,05895318 ! melanocyte differentiation GO:0030318 21 11 0,000 0,03097125 0,05890658 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,03097125 0,05886005 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,03097125 0,05881359 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,03097125 0,05876721 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,03097125 0,0587209 GO:0043088|regulation of Cdc42 GTPase activity, ! lipid digestion GO:0044241 18 11 0,000 0,03097125 0,05867466 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,03097125 0,0586285 ! UV protection GO:0009650 19 11 0,000 0,03097125 0,05858241 ! adult heart development GO:0007512 14 11 0,000 0,03097125 0,05853639 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,03097125 0,05849044 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,03097125 0,05844457 ! temperature homeostasis GO:0001659 17 11 0,000 0,03097125 0,05839876 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,03097125 0,05835303 ! negative regulation of ossification GO:0030279 26 11 0,000 0,03097125 0,05830737 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,03097125 0,05826178 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,03097125 0,05821627 ! regulation of organ growth GO:0046620 13 11 0,000 0,03097125 0,05817082 ! pigment granule localization GO:0051875 20 11 0,000 0,03097125 0,05812545 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,03097125 0,05808014 ! vasoconstriction GO:0042310 18 11 0,000 0,03097125 0,05803491 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,03097125 0,05798974 ! embryonic axis specification GO:0000578 18 11 0,000 0,03097125 0,05794465 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,03097125 0,05789963 ! snRNA metabolic process GO:0016073 24 11 0,000 0,03097125 0,05785467 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,03097125 0,05780979 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,03097125 0,05776498 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,03097125 0,05772023 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,03097125 0,05767556 ! zymogen activation GO:0031638 15 11 0,000 0,03097125 0,05763095 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,03097125 0,05758641 ! neuroblast proliferation GO:0007405 24 11 0,000 0,03097125 0,05754195 ! nucleosome positioning GO:0016584 15 11 0,000 0,03097125 0,05749755 ! regulation of isotype switching GO:0045191 22 11 0,000 0,03097125 0,05745322 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,03097125 0,05740895 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,03097125 0,05736476 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,03097125 0,05732063 ! acid secretion GO:0046717 18 11 0,000 0,03097125 0,05727657 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,03097125 0,05723258 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,03097125 0,05718866 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,03097125 0,0571448 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,03097125 0,05710101 ! oocyte differentiation GO:0009994 18 11 0,000 0,03097125 0,05705729 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,03097125 0,05701363 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! cholesterol efflux GO:0033344 19 11 0,000 0,03097125 0,05697005 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,03097125 0,05692652 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,03097125 0,05688307 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,03097125 0,05683968 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,03097125 0,05679636 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,03097125 0,0567531 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,03097125 0,05670991 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,03097125 0,05666678 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,03097125 0,05662372 ! defense response to fungus GO:0050832 13 11 0,000 0,03097125 0,05658073 ! developmental induction GO:0031128 19 11 0,000 0,03097125 0,0565378 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,03097125 0,05649494 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,03097125 0,05645214 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,03097125 0,0564094 ! sequestering of metal ion GO:0051238 14 11 0,000 0,03097125 0,05636673 ! lamellipodium assembly GO:0030032 20 11 0,000 0,03097125 0,05632413 ! nucleus localization GO:0051647 19 11 0,000 0,03097125 0,05628159 ! regulation of synapse organization GO:0050807 17 11 0,000 0,03097125 0,05623911 ! regulation of protein localization GO:0032880 176 97 1,000 0,03149873 0,05715381 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,03373935 0,06117323 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,03373935 0,06112716 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,03373935 0,06108117 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,03373935 0,06103524 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,03373935 0,06098939 ! cartilage condensation GO:0001502 20 12 0,000 0,03373935 0,0609436 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,03373935 0,06089788 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,03373935 0,06085223 ! protein complex disassembly GO:0043241 27 12 0,000 0,03373935 0,06080665 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,03373935 0,06076113 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,03373935 0,06071569 ! hippocampus development GO:0021766 26 12 0,000 0,03373935 0,06067031 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 0,03373935 0,060625 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,03373935 0,06057976 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,03373935 0,06053458 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,03373935 0,06048947 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,03373935 0,06044443 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,03373935 0,06039946 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,03373935 0,06035455 ! drug transport GO:0015893 16 12 0,000 0,03373935 0,06030971 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,03373935 0,06026494 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,03373935 0,06022023 ! polyamine metabolic process GO:0006595 17 12 0,000 0,03373935 0,06017559 ! focal adhesion formation GO:0048041 35 12 0,000 0,03373935 0,06013102 ! mitotic spindle organization GO:0007052 21 12 0,000 0,03373935 0,06008651 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,03373935 0,06004207 ! forebrain cell migration GO:0021885 21 12 0,000 0,03373935 0,05999769 ! asymmetric protein localization GO:0008105 20 12 0,000 0,03373935 0,05995338 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,03373935 0,05990913 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,03373935 0,05986495 ! entry into host cell GO:0030260 32 12 0,000 0,03373935 0,05982084 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,03373935 0,05977678 ! monoamine transport GO:0015844 18 12 0,000 0,03373935 0,0597328 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,03373935 0,05968888 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,03373935 0,05964502 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,03373935 0,05960123 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,03373935 0,0595575 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,03373935 0,05951384 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,03373935 0,05947024 ! protein homotetramerization GO:0051289 21 12 0,000 0,03373935 0,0594267 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,03373935 0,05938323 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,03373935 0,05933982 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,03373935 0,05929647 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,03373935 0,05925319 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,03373935 0,05920997 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,03373935 0,05916682 ! fucose catabolic process GO:0019317 22 12 0,000 0,03373935 0,05912372 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,03373935 0,05908069 ! histone methylation GO:0016571 26 12 0,000 0,03373935 0,05903773 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,03373935 0,05899482 ! autonomic nervous system development GO:0048483 24 12 0,000 0,03373935 0,05895198 ! gland morphogenesis GO:0022612 29 12 0,000 0,03373935 0,0589092 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,03373935 0,05886648 ! T cell homeostasis GO:0043029 25 12 0,000 0,03373935 0,05882382 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,03373935 0,05878123 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,03373935 0,05873869 ! spleen development GO:0048536 22 12 0,000 0,03373935 0,05869622 ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,03373935 0,05865381 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,03373935 0,05861146 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,03373935 0,05856917 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,03373935 0,05852695 ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,03373935 0,05848478 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,03373935 0,05844267 ! response to cold GO:0009409 17 12 0,000 0,03373935 0,05840063 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,03373935 0,05835864 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,03373935 0,05831672 ! cGMP metabolic process GO:0046068 18 13 0,000 0,03649964 0,06304244 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,03649964 0,06299722 ! regulation of chemokine production GO:0032642 18 13 0,000 0,03649964 0,06295206 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,03649964 0,06290696 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,03649964 0,06286193 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,03649964 0,06281697 ! lipid localization GO:0010876 28 13 0,000 0,03649964 0,06277207 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,03649964 0,06272723 ! organelle fusion GO:0048284 32 13 0,000 0,03649964 0,06268246 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,03649964 0,06263775 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,03649964 0,0625931 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,03649964 0,06254852 ! endocrine pancreas development GO:0031018 22 13 0,000 0,03649964 0,062504 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,03649964 0,06245955 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,03649964 0,06241515 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,03649964 0,06237083 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,03649964 0,06232656 ! methionine metabolic process GO:0006555 27 13 0,000 0,03649964 0,06228236 ! plasma membrane organization GO:0007009 24 13 0,000 0,03649964 0,06223822 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,03649964 0,06219414 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,03649964 0,06215012 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,03649964 0,06210617 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,03649964 0,06206228 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,03649964 0,06201845 ! cytokine metabolic process GO:0042107 22 13 0,000 0,03649964 0,06197468 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,03649964 0,06193097 ! exocrine system development GO:0035272 32 13 0,000 0,03649964 0,06188733 ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,03649964 0,06184375 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,03649964 0,06180023 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,03649964 0,06175677 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,03649964 0,06171337 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,03649964 0,06167003 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,03649964 0,06162675 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,03649964 0,06158354 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,03649964 0,06154038 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,03649964 0,06149728 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,03649964 0,06145425 ! ribosome assembly GO:0042255 17 13 0,000 0,03649964 0,06141127 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,03649964 0,06136836 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,03649964 0,0613255 ! chromatin silencing GO:0006342 26 13 0,000 0,03649964 0,06128271 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,03649964 0,06123997 ! regulation of epidermis development GO:0045682 19 13 0,000 0,03649964 0,0611973 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,03649964 0,06115468 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,03649964 0,06111212 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,03649964 0,06106963 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,03649964 0,06102719 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,03649964 0,06098481 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,03649964 0,06094249 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,03649964 0,06090022 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,03649964 0,06085802 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,03649964 0,06081587 ! embryonic placenta development GO:0001892 23 13 0,000 0,03649964 0,06077379 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,03649964 0,06073176 ! insulin secretion GO:0030073 23 13 0,000 0,03649964 0,06068979 ! actin filament polymerization GO:0030041 24 13 0,000 0,03649964 0,06064787 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,03649964 0,06060602 ! acrosome reaction GO:0007340 18 13 0,000 0,03649964 0,06056422 ! rRNA transcription GO:0009303 25 14 0,000 0,03925213 0,06508657 ! lactation GO:0007595 26 14 0,000 0,03925213 0,06504175 ! reproductive cellular process GO:0048610 20 14 0,000 0,03925213 0,06499698 ! tRNA modification GO:0006400 20 14 0,000 0,03925213 0,06495228 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,03925213 0,06490764 ! regulation of S phase GO:0033261 23 14 0,000 0,03925213 0,06486306 ! water transport GO:0006833 21 14 0,000 0,03925213 0,06481854 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,03925213 0,06477409 ! non-recombinational repair GO:0000726 25 14 0,000 0,03925213 0,06472969 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,03925213 0,06468536 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,03925213 0,06464108 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,03925213 0,06459687 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,03925213 0,06455271 ! RNA polyadenylation GO:0043631 30 14 0,000 0,03925213 0,06450862 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,03925213 0,06446459 ! palate development GO:0060021 31 14 0,000 0,03925213 0,06442061 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,03925213 0,0643767 ! regulated secretory pathway GO:0045055 23 14 0,000 0,03925213 0,06433285 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,03925213 0,06428905 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,03925213 0,06424532 ! arginine metabolic process GO:0006525 17 14 0,000 0,03925213 0,06420164 ! regulation of heart rate GO:0002027 24 14 0,000 0,03925213 0,06415803 ! organic alcohol transport GO:0015850 29 14 0,000 0,03925213 0,06411447 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,03925213 0,06407098 ! embryo implantation GO:0007566 30 14 0,000 0,03925213 0,06402754 ! neutral amino acid transport GO:0015804 26 14 0,000 0,03925213 0,06398416 ! L-amino acid transport GO:0015807 30 14 0,000 0,03925213 0,06394084 ! bone mineralization GO:0030282 17 14 0,000 0,03925213 0,06389758 ! stem cell development GO:0048864 43 14 0,000 0,03925213 0,06385437 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,03925213 0,06381123 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,03925213 0,06376814 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,03925213 0,06372511 ! cerebellum development GO:0021549 21 14 0,000 0,03925213 0,06368214 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,03925213 0,06363923 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,03925213 0,06359638 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,03925213 0,06355358 ! cofactor transport GO:0051181 26 14 0,000 0,03925213 0,06351084 ! NADP metabolic process GO:0006739 24 14 0,000 0,03925213 0,06346816 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,03925213 0,06342553 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,03925213 0,06338297 ! intestinal absorption GO:0050892 25 14 0,000 0,03925213 0,06334046 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,03925213 0,063298 ! oxygen transport GO:0015671 21 14 0,000 0,03925213 0,06325561 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,03925213 0,06321327 ! male genitalia development GO:0030539 24 14 0,000 0,03925213 0,06317098 ! regulation of RNA stability GO:0043487 32 14 0,000 0,03925213 0,06312876 ! regulation of axon extension GO:0030516 37 14 0,000 0,03925213 0,06308659 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,03925213 0,06304447 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,04199685 0,06740788 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,04199685 0,06736294 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! superoxide anion generation GO:0042554 20 15 0,000 0,04199685 0,06731807 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,04199685 0,06727325 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,04199685 0,06722849 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,04199685 0,06718379 ! copper ion transport GO:0006825 20 15 0,000 0,04199685 0,06713915 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,04199685 0,06709457 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,04199685 0,06705004 ! sulfate transport GO:0008272 23 15 0,000 0,04199685 0,06700558 ! response to cAMP GO:0051591 22 15 0,000 0,04199685 0,06696118 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,04199685 0,06691683 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,04199685 0,06687255 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,04199685 0,06682832 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,04199685 0,06678415 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,04199685 0,06674004 ! response to hexose stimulus GO:0009746 22 15 0,000 0,04199685 0,06669598 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,04199685 0,06665199 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,04199685 0,06660805 ! pituitary gland development GO:0021983 29 15 0,000 0,04199685 0,06656417 ! vesicle coating GO:0006901 33 15 0,000 0,04199685 0,06652035 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,04199685 0,06647659 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,04199685 0,06643288 ! regulation of exocytosis GO:0017157 22 15 0,000 0,04199685 0,06638924 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,04199685 0,06634564 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,04199685 0,06630211 ! regulation of vasodilation GO:0042312 26 15 0,000 0,04199685 0,06625863 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,04199685 0,06621521 ! histone deacetylation GO:0016575 20 15 0,000 0,04199685 0,06617185 ! mRNA splice site selection GO:0006376 38 15 0,000 0,04199685 0,06612854 ! tissue regeneration GO:0042246 26 15 0,000 0,04199685 0,0660853 ! water homeostasis GO:0030104 27 15 0,000 0,04199685 0,0660421 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,04199685 0,06599897 ! muscle maintenance GO:0046716 26 15 0,000 0,04199685 0,06595589 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,04199685 0,06591286 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,04199685 0,06586989 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,04199685 0,06582698 ! dopamine metabolic process GO:0042417 35 15 0,000 0,04199685 0,06578413 ! heme biosynthetic process GO:0006783 29 15 0,000 0,04199685 0,06574132 ! cell killing GO:0001906 29 15 0,000 0,04199685 0,06569858 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,04199685 0,06565589 ! detection of bacterium GO:0016045 18 15 0,000 0,04199685 0,06561326 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,04199685 0,06557068 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,04199685 0,06552816 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,04199685 0,06548569 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,04199685 0,06544327 ! peptide hormone processing GO:0016486 23 15 0,000 0,04199685 0,06540092 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,04473382 0,06961809 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,04473382 0,06957309 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,04473382 0,06952814 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,04473382 0,06948326 ! bone remodeling GO:0046849 27 16 0,000 0,04473382 0,06943843 ! filopodium assembly GO:0046847 32 16 0,000 0,04473382 0,06939366 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,04473382 0,06934895 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,04473382 0,06930429 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,04473382 0,0692597 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,04473382 0,06921516 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,04473382 0,06917067 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,04473382 0,06912625 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,04473382 0,06908188 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,04473382 0,06903757 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,04473382 0,06899331 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,04473382 0,06894911 ! protein polyubiquitination GO:0000209 34 16 0,000 0,04473382 0,06890497 ! glutamate metabolic process GO:0006536 22 16 0,000 0,04473382 0,06886089 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,04473382 0,06881686 ! response to osmotic stress GO:0006970 25 16 0,000 0,04473382 0,06877289 ! lysosomal transport GO:0007041 26 16 0,000 0,04473382 0,06872897 ! fructose metabolic process GO:0006000 25 16 0,000 0,04473382 0,06868511 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,04473382 0,0686413 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,04473382 0,06859756 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,04473382 0,06855386 ! negative regulation of immune response GO:0050777 35 16 0,000 0,04473382 0,06851023 ! axon cargo transport GO:0008088 43 16 0,000 0,04473382 0,06846665 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,04473382 0,06842312 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,04473382 0,06837965 ! DNA replication initiation GO:0006270 27 16 0,000 0,04473382 0,06833623 ! neuron recognition GO:0008038 35 16 0,000 0,04473382 0,06829287 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,04473382 0,06824957 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,04473382 0,06820632 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,04473382 0,06816312 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,04473382 0,06811998 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,04473382 0,06807689 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,04473382 0,06803386 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,04473382 0,06799088 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,04473382 0,06794796 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,04473382 0,06790509 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,04473382 0,06786227 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,04473382 0,06781951 ! defense response to virus GO:0051607 37 16 0,000 0,04473382 0,0677768 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,04746306 0,07186666 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,04746306 0,07182146 ! metencephalon development GO:0022037 30 17 0,000 0,04746306 0,07177632 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,04746306 0,07173123 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,04746306 0,0716862 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,04746306 0,07164123 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,04746306 0,07159631 ! signal complex assembly GO:0007172 41 17 0,000 0,04746306 0,07155145 ! endothelial cell migration GO:0043542 28 17 0,000 0,04746306 0,07150665 ! inositol metabolic process GO:0006020 28 17 0,000 0,04746306 0,0714619 ! gene silencing by RNA GO:0031047 36 17 0,000 0,04746306 0,07141721 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,04746306 0,07137258 ! glial cell development GO:0021782 27 17 0,000 0,04746306 0,071328 ! limbic system development GO:0021761 36 17 0,000 0,04746306 0,07128347 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,04746306 0,071239 ! adult walking behavior GO:0007628 33 17 0,000 0,04746306 0,07119459 ! heart looping GO:0001947 30 17 0,000 0,04746306 0,07115023 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,04746306 0,07110593 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,04746306 0,07106168 ! myoblast differentiation GO:0045445 45 17 0,000 0,04746306 0,07101749 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,04746306 0,07097335 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,04746306 0,07092927 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,04746306 0,07088524 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,04746306 0,07084127 ! glycine metabolic process GO:0006544 28 17 0,000 0,04746306 0,07079735 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,04746306 0,07075348 ! NAD metabolic process GO:0019674 29 17 0,000 0,04746306 0,07070967 ! membrane budding GO:0006900 37 17 0,000 0,04746306 0,07066592 ! DNA integration GO:0015074 29 17 0,000 0,04746306 0,07062221 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,04746306 0,07057857 ! regulation of protein binding GO:0043393 33 17 0,000 0,04746306 0,07053497 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,04746306 0,07049143 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,04746306 0,07044795 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,04746306 0,07040451 ! genitalia development GO:0048806 30 17 0,000 0,04746306 0,07036113 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,04746306 0,07031781 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,04746306 0,07027454 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,04746306 0,07023132 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,04746306 0,07018815 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,04746306 0,07014504 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,04746306 0,07010198 ! steroid catabolic process GO:0006706 31 17 0,000 0,04746306 0,07005897 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,04746306 0,07001602 ! gas transport GO:0015669 25 17 0,000 0,04746306 0,06997311 ! organic cation transport GO:0015695 31 17 0,000 0,04746306 0,06993026 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,04746306 0,06988747 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,04746306 0,06984472 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,04746306 0,06980203 ! microspike assembly GO:0030035 36 17 0,000 0,04746306 0,06975939 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,04746306 0,0697168 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,05018459 0,07366939 ! neuron maturation GO:0042551 42 18 0,000 0,05018459 0,07362447 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,05018459 0,0735796 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,05018459 0,07353479 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,05018459 0,07349004 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,05018459 0,07344534 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,05018459 0,07340069 ! memory GO:0007613 31 18 0,000 0,05018459 0,07335609 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,05018459 0,07331156 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,05018459 0,07326707 ! patterning of blood vessels GO:0001569 39 18 0,000 0,05018459 0,07322264 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,05018459 0,07317826 GO:0042744|hydrogen peroxide catabolic process, ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,05018459 0,07313394 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,05018459 0,07308967 ! glutamine metabolic process GO:0006541 29 18 0,000 0,05018459 0,07304545 ! response to retinoic acid GO:0032526 26 18 0,000 0,05018459 0,07300129 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,05018459 0,07295718 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,05018459 0,07291312 ! response to fungus GO:0009620 21 18 0,000 0,05018459 0,07286912 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,05018459 0,07282517 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,05018459 0,07278127 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,05018459 0,07273743 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,05018459 0,07269364 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,05018459 0,0726499 ! vitamin transport GO:0051180 27 18 0,000 0,05018459 0,07260621 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,05018459 0,07256258 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,05018459 0,072519 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,05018459 0,07247547 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,05018459 0,07243199 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,05018459 0,07238857 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,05018459 0,0723452 ! protein secretion GO:0009306 39 19 0,000 0,05289844 0,07621177 ! positive regulation of translation GO:0045727 30 19 0,000 0,05289844 0,07616616 ! negative regulation of defense response GO:0031348 25 19 0,000 0,05289844 0,0761206 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,05289844 0,07607511 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,05289844 0,07602966 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,05289844 0,07598427 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,05289844 0,07593893 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,05289844 0,07589365 ! bile acid metabolic process GO:0008206 29 19 0,000 0,05289844 0,07584842 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,05289844 0,07580325 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,05289844 0,07575813 ! cerebral cortex development GO:0021987 36 19 0,000 0,05289844 0,07571306 ! pigmentation during development GO:0048066 41 19 0,000 0,05289844 0,07566804 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,05289844 0,07562308 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,05289844 0,07557818 ! heme metabolic process GO:0042168 36 19 0,000 0,05289844 0,07553332 ! actin filament bundle formation GO:0051017 42 19 0,000 0,05289844 0,07548852 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,05289844 0,07544378 ! plasma membrane fusion GO:0045026 28 19 0,000 0,05289844 0,07539908 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,05289844 0,07535444 ! peptide cross-linking GO:0018149 37 19 0,000 0,05289844 0,07530985 ! protein export from nucleus GO:0006611 36 19 0,000 0,05289844 0,07526532 ! heart process GO:0003015 30 19 0,000 0,05289844 0,07522083 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,05289844 0,0751764 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,05289844 0,07513203 ! visual learning GO:0008542 36 19 0,000 0,05289844 0,0750877 ! cellular pigmentation GO:0033059 36 19 0,000 0,05289844 0,07504343 ! G1 phase GO:0051318 40 19 0,000 0,05289844 0,07499921 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,05289844 0,07495504 ! cell-cell junction organization GO:0045216 35 19 0,000 0,05289844 0,07491092 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,05289844 0,07486685 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,05289844 0,07482284 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,05289844 0,07477888 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,05289844 0,07473497 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,05289844 0,07469111 ! cilium assembly GO:0042384 37 19 0,000 0,05289844 0,0746473 ! peptide hormone secretion GO:0030072 31 19 0,000 0,05289844 0,07460355 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,05560463 0,07837418 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,05560463 0,0783283 ! positive regulation of ossification GO:0045778 47 20 0,000 0,05560463 0,07828246 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,05560463 0,07823668 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,05560463 0,07819096 ! cAMP metabolic process GO:0046058 36 20 0,000 0,05560463 0,07814529 ! response to vitamin GO:0033273 31 20 0,000 0,05560463 0,07809967 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,05560463 0,0780541 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,05560463 0,07800859 ! response to alkaloid GO:0043279 38 20 0,000 0,05560463 0,07796313 ! retinoid metabolic process GO:0001523 32 20 0,000 0,05560463 0,07791772 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,05560463 0,07787237 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,05560463 0,07782707 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,05560463 0,07778182 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,05560463 0,07773662 GO:0032392|DNA geometric change, ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,05560463 0,07769148 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,05560463 0,07764639 ! body fluid secretion GO:0007589 31 20 0,000 0,05560463 0,07760135 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,05560463 0,07755637 ! peptide secretion GO:0002790 35 20 0,000 0,05560463 0,07751143 ! stem cell differentiation GO:0048863 53 20 0,000 0,05560463 0,07746655 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,05560463 0,07742172 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,05560463 0,07737694 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,05560463 0,07733221 ! sensory perception of pain GO:0019233 30 20 0,000 0,05560463 0,07728754 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,05560463 0,07724292 ! diencephalon development GO:0021536 34 20 0,000 0,05560463 0,07719834 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,05560463 0,07715382 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,05560463 0,07710935 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,05560463 0,07706494 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,05560463 0,07702057 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,05560463 0,07697625 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,05560463 0,07693199 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,05560463 0,07688778 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,05560463 0,07684361 ! regulation of glucose import GO:0046324 29 20 0,000 0,05560463 0,0767995 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,05560463 0,07675544 ! actin filament-based movement GO:0030048 43 20 0,000 0,05560463 0,07671143 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,05560463 0,07666747 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,05560463 0,07662356 ! negative regulation of translation GO:0017148 29 20 0,000 0,05560463 0,0765797 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,05560463 0,07653589 ! regulation of cell killing GO:0031341 42 21 0,000 0,05830317 0,08020436 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,05830317 0,08015853 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,05830317 0,08011275 ! hormone secretion GO:0046879 38 21 0,000 0,05830317 0,08006702 ! glycerol metabolic process GO:0006071 34 21 0,000 0,05830317 0,08002135 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,05830317 0,07997572 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,05830317 0,07993015 ! axis specification GO:0009798 38 21 0,000 0,05830317 0,07988464 ! ovarian follicle development GO:0001541 35 21 0,000 0,05830317 0,07983917 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,05830317 0,07979375 ! smooth muscle contraction GO:0006939 46 21 0,000 0,05830317 0,07974839 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,05830317 0,07970308 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,05830317 0,07965782 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,05830317 0,07961261 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,05830317 0,07956745 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,05830317 0,07952235 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,05830317 0,07947729 ! cytolysis GO:0019835 24 21 0,000 0,05830317 0,07943229 ! vasodilation GO:0042311 39 21 0,000 0,05830317 0,07938734 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,05830317 0,07934243 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,05830317 0,07929758 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,05830317 0,07925278 ! oogenesis GO:0048477 36 21 0,000 0,05830317 0,07920803 ! DNA modification GO:0006304 34 21 0,000 0,05830317 0,07916333 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,05830317 0,07911868 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,05830317 0,07907408 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,05830317 0,07902953 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,05830317 0,07898503 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,05830317 0,07894059 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,05830317 0,07889619 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,05830317 0,07885184 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,05830317 0,07880754 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,05830317 0,07876329 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,05830317 0,07871909 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,05830317 0,07867494 ! collagen catabolic process GO:0030574 28 21 0,000 0,05830317 0,07863084 ! sperm-egg recognition GO:0035036 21 21 0,000 0,05830317 0,07858679 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,06099409 0,08216785 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,06099409 0,08212187 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,06099409 0,08207594 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,06099409 0,08203006 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,06099409 0,08198423 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,06099409 0,08193846 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,06099409 0,08189273 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,06099409 0,08184706 ! regeneration GO:0031099 41 22 0,000 0,06099409 0,08180144 ! keratinization GO:0031424 28 22 0,000 0,06099409 0,08175586 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,06099409 0,08171034 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,06099409 0,08166487 ! sensory perception of taste GO:0050909 28 22 0,000 0,06099409 0,08161945 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,06099409 0,08157408 ! vacuolar transport GO:0007034 36 22 0,000 0,06099409 0,08152876 ! lysosome organization GO:0007040 41 22 0,000 0,06099409 0,0814835 ! central nervous system neuron development GO:0021954 46 22 0,000 0,06099409 0,08143828 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,06099409 0,08139311 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,06099409 0,08134799 ! fucose metabolic process GO:0006004 39 22 0,000 0,06099409 0,08130292 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,06099409 0,0812579 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,06099409 0,08121294 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,06099409 0,08116802 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,06099409 0,08112315 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,06099409 0,08107833 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,06099409 0,08103356 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,06099409 0,08098884 ! sarcomere organization GO:0045214 30 22 0,000 0,06099409 0,08094417 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,06099409 0,08089954 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,06099409 0,08085497 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,06099409 0,08081045 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,06099409 0,08076597 ! protein stabilization GO:0050821 39 22 0,000 0,06099409 0,08072155 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,06367741 0,08422641 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,06367741 0,08418013 ! gluconeogenesis GO:0006094 33 23 0,000 0,06367741 0,08413391 ! viral genome replication GO:0019079 41 23 0,000 0,06367741 0,08408773 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,06367741 0,0840416 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,06367741 0,08399553 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,06367741 0,0839495 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,06367741 0,08390353 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,06367741 0,0838576 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,06367741 0,08381173 ! visual behavior GO:0007632 42 23 0,000 0,06367741 0,08376591 ! regulation of cell-matrix adhesion GO:0001952 78 23 0,000 0,06367741 0,08372013 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 48 23 0,000 0,06367741 0,08367441 ! response to ethanol GO:0045471 46 23 0,000 0,06367741 0,08362873 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,06367741 0,08358311 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,06367741 0,08353754 ! peroxisome organization GO:0007031 37 23 0,000 0,06367741 0,08349201 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,06367741 0,08344654 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,06367741 0,08340111 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,06367741 0,08335574 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,06367741 0,08331041 GO:0051693|actin filament capping, ! regulation of viral reproduction GO:0050792 38 23 0,000 0,06367741 0,08326513 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,06367741 0,0832199 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,06367741 0,08317472 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,06367741 0,08312959 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,06367741 0,08308451 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,06367741 0,08303948 ! fatty acid transport GO:0015908 44 23 0,000 0,06367741 0,0829945 ! platelet activation GO:0030168 37 23 0,000 0,06367741 0,08294956 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,06367741 0,08290468 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,06367741 0,08285984 ! hormone transport GO:0009914 40 23 0,000 0,06367741 0,08281505 ! cell-cell recognition GO:0009988 25 23 0,000 0,06367741 0,08277031 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,06367741 0,08272562 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,06367741 0,08268097 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,06367741 0,08263638 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,06367741 0,08259183 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,06367741 0,08254733 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,06635315 0,08596967 GO:0016444|somatic cell DNA recombination, ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,06635315 0,0859234 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,06635315 0,08587718 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,06635315 0,08583101 ! vesicle docking GO:0048278 47 24 0,000 0,06635315 0,08578489 ! vacuole organization GO:0007033 43 24 0,000 0,06635315 0,08573882 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,06635315 0,08569279 ! digestive system process GO:0022600 39 24 0,000 0,06635315 0,08564682 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,06635315 0,0856009 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,06635315 0,08555502 ! regulation of behavior GO:0050795 43 24 0,000 0,06635315 0,0855092 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,06635315 0,08546342 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,06635315 0,0854177 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,06635315 0,08537202 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,06635315 0,08532639 ! membrane depolarization GO:0051899 39 24 0,000 0,06635315 0,08528081 ! pallium development GO:0021543 49 24 0,000 0,06635315 0,08523528 ! pentose metabolic process GO:0019321 35 24 0,000 0,06635315 0,08518979 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,06635315 0,08514436 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,06635315 0,08509897 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,06635315 0,08505364 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,06635315 0,08500835 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,06635315 0,0849631 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,06635315 0,08491791 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,06635315 0,08487277 ! regulation of amine transport GO:0051952 40 24 0,000 0,06635315 0,08482767 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,06902133 0,08819189 ! phototransduction GO:0007602 33 25 0,000 0,06902133 0,08814508 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,06902133 0,08809831 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 0,000 0,06902133 0,0880516 ! sperm motility GO:0030317 31 25 0,000 0,06902133 0,08800494 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,06902133 0,08795833 ! receptor metabolic process GO:0043112 46 25 0,000 0,06902133 0,08791176 ! chromosome condensation GO:0030261 45 25 0,000 0,06902133 0,08786525 ! neural crest cell development GO:0014032 54 25 0,000 0,06902133 0,08781878 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,06902133 0,08777237 ! regulation of insulin secretion GO:0050796 37 25 0,000 0,06902133 0,087726 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,06902133 0,08767968 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,06902133 0,08763342 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,06902133 0,0875872 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,06902133 0,08754102 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! immunoglobulin production GO:0002377 55 25 0,000 0,06902133 0,0874949 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,06902133 0,08744883 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,06902133 0,0874028 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,06902133 0,08735682 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,06902133 0,0873109 ! telomere organization GO:0032200 43 25 0,000 0,06902133 0,08726501 GO:0000723|telomere maintenance, ! liver development GO:0001889 53 25 0,000 0,06902133 0,08721918 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,07168198 0,09053377 ! embryonic pattern specification GO:0009880 44 26 0,000 0,07168198 0,09048627 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,07168198 0,09043882 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,07168198 0,09039142 ! initiation of viral infection GO:0019059 57 26 0,000 0,07168198 0,09034407 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,07168198 0,09029677 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,07168198 0,09024952 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,07168198 0,09020232 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,07168198 0,09015517 ! molting cycle process GO:0022404 50 26 0,000 0,07168198 0,09010807 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,07168198 0,09006101 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,07168198 0,09001401 ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,07168198 0,08996705 ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,07168198 0,08992014 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,07168198 0,08987329 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,07168198 0,08982648 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,07168198 0,08977972 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,07168198 0,08973301 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,07168198 0,08968634 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,07168198 0,08963973 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,07168198 0,08959316 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,07168198 0,08954664 ! blastocyst development GO:0001824 49 26 0,000 0,07168198 0,08950017 ! leukocyte proliferation GO:0070661 52 26 0,000 0,07168198 0,08945375 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,07168198 0,08940738 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,07168198 0,08936106 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,07433511 0,09262054 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,07433511 0,0925726 ! iron ion transport GO:0006826 59 27 0,000 0,07433511 0,09252471 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,07433511 0,09247687 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,07433511 0,09242908 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,07433511 0,09238134 ! fat cell differentiation GO:0045444 50 27 0,000 0,07433511 0,09233364 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,07433511 0,092286 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,07433511 0,09223841 ! autophagy GO:0006914 41 27 0,000 0,07433511 0,09219086 ! male gonad development GO:0008584 44 27 0,000 0,07433511 0,09214336 ! response to toxin GO:0009636 47 27 0,000 0,07433511 0,09209592 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,07433511 0,09204852 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,07433511 0,09200117 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,07433511 0,09195387 ! glutathione metabolic process GO:0006749 39 27 0,000 0,07433511 0,09190661 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,07433511 0,09185941 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,07433511 0,09181225 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,07433511 0,09176515 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,07698074 0,09498239 ! circadian rhythm GO:0007623 50 28 0,000 0,07698074 0,09493371 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,07698074 0,09488508 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,07698074 0,09483649 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,07698074 0,09478796 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,07698074 0,09473947 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,07698074 0,09469104 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,07698074 0,09464265 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,07698074 0,09459432 ! synaptogenesis GO:0007416 42 28 0,000 0,07698074 0,09454603 ! lipid oxidation GO:0034440 43 28 0,000 0,07698074 0,09449779 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,07698074 0,0944496 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,07698074 0,09440146 ! translational initiation GO:0006413 65 29 0,000 0,07961891 0,0975869 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,07961891 0,09753721 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,07961891 0,09748758 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,07961891 0,09743799 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,07961891 0,09738845 ! catechol metabolic process GO:0009712 54 29 0,000 0,07961891 0,09733897 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,07961891 0,09728953 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,07961891 0,09724015 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,07961891 0,09719081 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,07961891 0,09714152 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,07961891 0,09709229 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,07961891 0,0970431 ! cell fate determination GO:0001709 60 29 0,000 0,07961891 0,09699397 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,07961891 0,09694488 ! detection of light stimulus GO:0009583 38 29 0,000 0,07961891 0,09689585 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,07961891 0,09684686 ! tissue homeostasis GO:0001894 48 29 0,000 0,07961891 0,09679792 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,07961891 0,09674903 ! phenol metabolic process GO:0018958 55 30 0,000 0,08224961 0,09989529 ! zinc ion transport GO:0006829 45 30 0,000 0,08224961 0,09984489 ! membrane docking GO:0022406 61 30 0,000 0,08224961 0,09979454 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,08224961 0,09974424 ! cell junction assembly GO:0034329 78 30 0,000 0,08224961 0,09969399 ! regulation of innate immune response GO:0045088 51 30 0,000 0,08224961 0,09964379 ! acute-phase response GO:0006953 49 30 0,000 0,08224961 0,09959365 ! myofibril assembly GO:0030239 47 30 0,000 0,08224961 0,09954355 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,08224961 0,0994935 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,08224961 0,0994435 ! phospholipid transport GO:0015914 51 30 0,000 0,08224961 0,09939356 ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,08224961 0,09934366 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,08224961 0,09929381 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,08224961 0,09924402 ! response to heat GO:0009408 50 30 0,000 0,08224961 0,09919427 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,08487289 0,1023067 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,08487289 0,10225547 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,08487289 0,10220429 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,08487289 0,10215317 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,08487289 0,10210209 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,08487289 0,10205106 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,08487289 0,10200009 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,08487289 0,10194916 ! ovulation cycle process GO:0022602 49 31 0,000 0,08487289 0,10189829 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,08487289 0,10184747 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,08487289 0,1017967 ! peptide transport GO:0015833 55 31 0,000 0,08487289 0,10174598 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,08487289 0,10169531 ! iron ion homeostasis GO:0055072 54 31 0,000 0,08487289 0,10164469 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,08487289 0,10159412 ! mesoderm formation GO:0001707 69 31 0,000 0,08487289 0,1015436 ! natural killer cell activation GO:0030101 45 31 0,000 0,08487289 0,10149313 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,08487289 0,10144271 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,08487289 0,10139234 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,08487289 0,10134202 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,08487289 0,10129175 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,08487289 0,10124154 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,08748876 0,10431018 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,08748876 0,10425852 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,08748876 0,10420691 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,08748876 0,10415534 ! cholesterol transport GO:0030301 56 32 0,000 0,08748876 0,10410383 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,08748876 0,10405237 ! spliceosome assembly GO:0000245 67 32 0,000 0,08748876 0,10400096 ! spindle organization GO:0007051 46 32 0,000 0,08748876 0,1039496 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,08748876 0,1038983 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,08748876 0,10384704 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,08748876 0,10379583 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,08748876 0,10374468 ! muscle cell development GO:0055001 49 32 0,000 0,08748876 0,10369357 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,08748876 0,10364252 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,08748876 0,10359151 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,08748876 0,10354056 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,08748876 0,10348965 ! ovulation cycle GO:0042698 51 32 0,000 0,08748876 0,1034388 ! BMP signaling pathway GO:0030509 64 32 0,000 0,08748876 0,10338799 ! hindbrain development GO:0030902 61 32 0,000 0,08748876 0,10333724 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,08748876 0,10328653 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,08748876 0,10323588 ! gene silencing GO:0016458 65 32 0,000 0,08748876 0,10318527 ! post-embryonic development GO:0009791 69 33 0,000 0,09009723 0,10620967 ! protein targeting to membrane GO:0006612 68 33 0,000 0,09009723 0,10615766 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,09009723 0,1061057 ! ceramide metabolic process GO:0006672 64 33 0,000 0,09009723 0,10605379 ! formation of primary germ layer GO:0001704 72 33 0,000 0,09009723 0,10600193 ! sterol transport GO:0015918 57 33 0,000 0,09009723 0,10595012 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,09009723 0,10589836 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,09009723 0,10584665 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,09009723 0,10579499 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,09009723 0,10574339 ! glial cell differentiation GO:0010001 63 34 0,000 0,09269834 0,10874315 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,09269834 0,10869016 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,09269834 0,10863721 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,09269834 0,10858432 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,09269834 0,10853148 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,09269834 0,1084787 ! spermatid development GO:0007286 63 34 0,000 0,09269834 0,10842596 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,09269834 0,10837327 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,09269834 0,10832064 ! placenta development GO:0001890 53 34 0,000 0,09269834 0,10826806 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,09529209 0,11124346 ! negative regulation of secretion GO:0051048 63 35 0,000 0,09529209 0,11118951 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,09529209 0,11113561 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,09529209 0,11108177 ! female gonad development GO:0008585 58 35 0,000 0,09529209 0,11102798 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,09529209 0,11097424 GO:0006639|acylglycerol metabolic process, ! cytokine production GO:0001816 59 35 0,000 0,09529209 0,11092055 ! vesicle localization GO:0051648 64 35 0,000 0,09529209 0,11086691 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,09787852 0,11382103 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,09787852 0,11376605 ! cell junction organization GO:0034330 86 36 0,000 0,09787852 0,11371111 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,09787852 0,11365623 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,09787852 0,11360141 ! positive regulation of cell development GO:0010720 80 36 0,000 0,09787852 0,11354663 ! regulation of proteolysis GO:0030162 72 36 0,000 0,09787852 0,11349191 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,09787852 0,11343724 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,09787852 0,11338263 ! aerobic respiration GO:0009060 55 36 0,000 0,09787852 0,11332806 ! androgen receptor signaling pathway GO:0030521 74 36 0,000 0,09787852 0,11327355 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,09787852 0,11321909 ! RNA export from nucleus GO:0006405 56 37 0,000 0,10045764 0,1161466 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,10045764 0,11609081 ! meiosis I GO:0007127 65 37 0,000 0,10045764 0,11603508 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,10045764 0,1159794 ! sister chromatid segregation GO:0000819 58 37 0,000 0,10045764 0,11592378 ! actomyosin structure organization GO:0031032 62 37 0,000 0,10045764 0,1158682 ! organic anion transport GO:0015711 68 37 0,000 0,10045764 0,11581268 ! tissue remodeling GO:0048771 76 37 0,000 0,10045764 0,11575722 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,10045764 0,11570181 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,10045764 0,11564645 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,10045764 0,11559114 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,10045764 0,11553589 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,10045764 0,11548068 ! glycogen metabolic process GO:0005977 61 37 0,000 0,10045764 0,11542554 ! pigment metabolic process GO:0042440 80 37 0,000 0,10045764 0,11537044 ! spermatid differentiation GO:0048515 66 37 0,000 0,10045764 0,1153154 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,10302947 0,1182112 GO:0006956|complement activation, ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,10302947 0,11815486 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,10302947 0,11809857 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,10302947 0,11804233 ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,10302947 0,11798615 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 0,000 0,10302947 0,11793002 ! lipid homeostasis GO:0055088 67 38 0,000 0,10302947 0,11787394 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,10302947 0,11781792 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,10302947 0,11776195 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,10302947 0,11770603 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,10302947 0,11765016 ! glucan metabolic process GO:0044042 62 38 0,000 0,10302947 0,11759435 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,10559403 0,12046431 ! learning GO:0007612 77 39 0,000 0,10559403 0,12040722 ! ear morphogenesis GO:0042471 60 39 0,000 0,10559403 0,12035018 ! organic ether metabolic process GO:0018904 55 39 0,000 0,10559403 0,1202932 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,10559403 0,12023627 ! ion transmembrane transport GO:0034220 66 39 0,000 0,10559403 0,12017939 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,10559403 0,12012257 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,10559403 0,1200658 ! RNA modification GO:0009451 57 39 0,000 0,10559403 0,12000908 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,10559403 0,11995242 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,10815134 0,1227995 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,10815134 0,12274157 ! feeding behavior GO:0007631 59 40 0,000 0,10815134 0,1226837 ! negative regulation of binding GO:0051100 72 40 0,000 0,10815134 0,12262589 ! mesenchymal cell development GO:0014031 87 40 0,000 0,10815134 0,12256813 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,10815134 0,12251042 ! maintenance of protein location GO:0045185 91 40 0,000 0,10815134 0,12245277 ! cytokinesis GO:0000910 72 40 0,000 0,10815134 0,12239517 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,11070143 0,12522221 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,11070143 0,12516337 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,11070143 0,12510458 ! gliogenesis GO:0042063 88 41 0,000 0,11070143 0,12504584 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,11070143 0,12498716 ! female gamete generation GO:0007292 61 41 0,000 0,11070143 0,12492854 ! polyol metabolic process GO:0019751 66 41 0,000 0,11070143 0,12486997 ! response to reactive oxygen species GO:0000302 67 42 0,000 0,11324431 0,12767845 ! regulation of tube size GO:0035150 71 42 0,000 0,11324431 0,12761865 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,11324431 0,1275589 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,11324431 0,12749921 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,11324431 0,12743958 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,11324431 0,12738 ! regulation of protein secretion GO:0050708 71 42 0,000 0,11324431 0,12732047 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,11324431 0,12726101 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,11578001 0,13004981 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,11578001 0,12998912 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,11578001 0,12992849 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,11578001 0,12986792 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,11578001 0,12980741 ! glucose transport GO:0015758 65 43 0,000 0,11578001 0,12974695 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,11578001 0,12968654 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,11578001 0,12962619 ! striated muscle contraction GO:0006941 77 43 0,000 0,11578001 0,1295659 ! phagocytosis GO:0006909 90 43 0,000 0,11578001 0,12950567 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,11578001 0,12944549 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,11830853 0,13221102 ! hexose transport GO:0008645 67 44 0,000 0,11830853 0,13214964 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,11830853 0,13208832 ! male sex differentiation GO:0046661 76 44 0,000 0,11830853 0,13202705 ! biopolymer methylation GO:0043414 84 44 0,000 0,11830853 0,13196585 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,11830853 0,13190469 ! maintenance of location in cell GO:0051651 97 44 0,000 0,11830853 0,1318436 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,12082991 0,1345911 ! glycolysis GO:0006096 65 45 0,000 0,12082991 0,13452882 ! leukocyte migration GO:0050900 68 45 0,000 0,12082991 0,13446659 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,12082991 0,13440442 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,12082991 0,13434231 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,12082991 0,13428026 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,12082991 0,13421827 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,12082991 0,13415633 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,12082991 0,13409445 ! cell growth GO:0016049 84 45 0,000 0,12082991 0,13403263 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,12334417 0,13675855 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,12334417 0,13669556 ! pigmentation GO:0043473 100 46 0,000 0,12334417 0,13663263 ! positive regulation of defense response GO:0031349 76 47 0,000 0,12585131 0,13934572 ! response to calcium ion GO:0051592 81 47 0,000 0,12585131 0,13928163 ! endosome transport GO:0016197 108 47 0,000 0,12585131 0,13921759 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,12585131 0,13915361 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,12585131 0,13908969 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,12585131 0,13902583 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,12585131 0,13896203 ! methylation GO:0032259 90 47 0,000 0,12585131 0,13889828 ! protein homooligomerization GO:0051260 76 47 0,000 0,12585131 0,1388346 ! Notch signaling pathway GO:0007219 96 48 0,000 0,12835137 0,14152768 ! cellular component disassembly GO:0022411 86 48 0,000 0,12835137 0,14146285 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,12835137 0,14139808 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,12835137 0,14133336 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,12835137 0,14126871 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,12835137 0,14120412 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,13084436 0,14388096 ! regulation of ion transport GO:0043269 77 49 0,000 0,13084436 0,14381523 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,13084436 0,14374956 ! peptide metabolic process GO:0006518 76 49 0,000 0,13084436 0,14368395 ! response to temperature stimulus GO:0009266 76 49 0,000 0,13084436 0,1436184 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,13084436 0,14355291 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,13084436 0,14348748 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,13084436 0,14342211 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,13084436 0,1433568 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,13084436 0,14329155 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,13333031 0,14594755 ! regulation of ossification GO:0030278 117 50 0,000 0,13333031 0,14588118 ! inner ear development GO:0048839 79 50 0,000 0,13333031 0,14581487 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,13333031 0,14574862 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,13333031 0,14568244 ! viral infectious cycle GO:0019058 99 51 0,000 0,13580923 0,14832365 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,13580923 0,14825635 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,13580923 0,14818911 ! excretion GO:0007588 83 51 0,000 0,13580923 0,14812194 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,13580923 0,14805482 ! chromatin remodeling GO:0006338 109 51 0,000 0,13580923 0,14798777 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,13580923 0,14792078 ! vesicle organization GO:0016050 107 51 0,000 0,13580923 0,14785384 ! regulation of cell shape GO:0008360 125 51 0,000 0,13580923 0,14778697 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,13828113 0,15040886 ! membrane fusion GO:0006944 110 52 0,000 0,13828113 0,1503409 ! amino acid activation GO:0043038 92 52 0,000 0,13828113 0,15027299 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,13828113 0,15020515 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,14074605 0,15281363 ! RNA catabolic process GO:0006401 93 53 0,000 0,14074605 0,1527447 ! regulation of translational initiation GO:0006446 82 53 0,000 0,14074605 0,15267584 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,14074605 0,15260703 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,14074605 0,15253829 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,14074605 0,15246961 ! cell maturation GO:0048469 100 53 0,000 0,14074605 0,15240099 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,14074605 0,15233244 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,14320401 0,15492304 ! cell recognition GO:0008037 85 54 0,000 0,14320401 0,15485341 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,14320401 0,15478384 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,14320401 0,15471434 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,14320401 0,1546449 ! chloride transport GO:0006821 90 55 0,000 0,14565501 0,15722115 ! glucose catabolic process GO:0006007 82 55 0,000 0,14565501 0,15715065 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,14565501 0,15708021 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,14565501 0,15700983 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,14565501 0,15693952 ! gastrulation GO:0007369 112 55 0,000 0,14565501 0,15686927 ! RNA elongation GO:0006354 79 55 0,000 0,14565501 0,15679908 ! nuclear export GO:0051168 97 55 0,000 0,14565501 0,15672896 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,14565501 0,15665889 ! regulation of actin filament length GO:0030832 105 56 0,000 0,14809908 0,15921643 ! sensory perception of smell GO:0007608 80 56 0,000 0,14809908 0,15914532 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,14809908 0,15907428 ! proton transport GO:0015992 94 56 0,000 0,14809908 0,15900329 ! positive regulation of organelle organization GO:0010638 100 56 0,000 0,14809908 0,15893237 ! regulation of bone remodeling GO:0046850 137 57 0,000 0,15053624 0,16147579 ! maintenance of location GO:0051235 118 57 0,000 0,15053624 0,16140383 ! hydrogen transport GO:0006818 97 58 0,000 0,15296651 0,16393649 ! regulation of tissue remodeling GO:0034103 140 58 0,000 0,15296651 0,1638635 ! regulation of endocytosis GO:0030100 91 58 0,000 0,15296651 0,16379057 ! positive regulation of secretion GO:0051047 95 59 0,000 0,1553899 0,16631144 ! regulation of cellular component size GO:0032535 109 59 0,000 0,1553899 0,16623749 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,1553899 0,1661636 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,1553899 0,16608979 ! DNA catabolic process GO:0006308 86 59 0,000 0,1553899 0,16601603 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,1553899 0,16594235 ! establishment of organelle localization GO:0051656 109 59 0,000 0,1553899 0,16586873 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,15780645 0,16837353 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,15780645 0,1682989 ! regulation of heart contraction GO:0008016 110 60 0,000 0,15780645 0,16822433 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,15780645 0,16814983 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,16021616 0,17064191 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,16021616 0,1705664 ! mesoderm development GO:0007498 119 61 0,000 0,16021616 0,17049097 ! tRNA processing GO:0008033 89 61 0,000 0,16021616 0,17041559 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,16021616 0,17034029 ! ear development GO:0043583 103 62 0,000 0,16261905 0,17281866 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,16261905 0,17274236 ! gonad development GO:0008406 98 62 0,000 0,16261905 0,17266613 ! regulation of homeostatic process GO:0032844 134 62 0,000 0,16261905 0,17258996 ! regulation of mitosis GO:0007088 105 63 0,000 0,16501515 0,17505576 GO:0051783|regulation of nuclear division, ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,16501515 0,1749786 ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,16501515 0,17490152 ! detection of external stimulus GO:0009581 91 63 0,000 0,16501515 0,17482451 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,16501515 0,17474756 ! steroid hormone receptor signaling pathway GO:0030518 129 63 0,000 0,16501515 0,17467068 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,16740447 0,17712188 ! cell redox homeostasis GO:0045454 102 64 0,000 0,16740447 0,17704403 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,16740447 0,17696624 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,16740447 0,17688852 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,16740447 0,17681087 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,16978704 0,17924862 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,16978704 0,17917001 ! germ cell development GO:0007281 118 65 0,000 0,16978704 0,17909146 ! myeloid cell differentiation GO:0030099 111 65 0,000 0,16978704 0,17901298 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,17216286 0,18143839 ! actin filament organization GO:0007015 148 66 0,000 0,17216286 0,18135895 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,17216286 0,18127958 ! extracellular matrix organization GO:0030198 133 66 0,000 0,17216286 0,18120028 ! secondary metabolic process GO:0019748 116 66 0,000 0,17216286 0,18112105 ! developmental maturation GO:0021700 116 66 0,000 0,17216286 0,18104189 ! cell projection assembly GO:0030031 120 66 0,000 0,17216286 0,1809628 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,17453197 0,18337289 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,17453197 0,18329285 ! chromosome segregation GO:0007059 113 67 0,000 0,17453197 0,18321288 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,17453197 0,18313298 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,17453197 0,18305315 ! hexose catabolic process GO:0019320 104 67 0,000 0,17453197 0,18297339 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,17453197 0,18289369 ! adaptive immune response GO:0002250 119 67 0,000 0,17453197 0,18281407 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,17453197 0,18273452 ! amino acid transport GO:0006865 125 68 0,000 0,17689437 0,18512739 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,17689437 0,1850469 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,17689437 0,18496648 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 0,000 0,17689437 0,18488613 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,17689437 0,18480585 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,17689437 0,18472564 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,1792501 0,18710444 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,1792501 0,1870233 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,1792501 0,18694223 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,1792501 0,18686124 ! antigen processing and presentation GO:0019882 104 69 0,000 0,1792501 0,18678031 ! amine catabolic process GO:0009310 117 71 0,000 0,18394157 0,19158589 ! reproductive structure development GO:0048608 113 71 0,000 0,18394157 0,19150299 ! humoral immune response GO:0006959 109 71 0,000 0,18394157 0,19142016 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,18394157 0,1913374 ! regulation of immune effector process GO:0002697 137 71 0,000 0,18394157 0,19125471 ! acute inflammatory response GO:0002526 113 72 0,000 0,18627735 0,1935997 ! carbohydrate transport GO:0008643 110 72 0,000 0,18627735 0,19351611 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,18627735 0,19343259 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,18627735 0,19334914 ! learning or memory GO:0007611 147 73 0,000 0,18860653 0,19568233 ! regulation of blood pressure GO:0008217 125 73 0,000 0,18860653 0,19559798 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,18860653 0,19551371 ! fertilization GO:0009566 90 73 0,000 0,18860653 0,19542951 ! transition metal ion transport GO:0000041 126 74 0,000 0,19092912 0,19775095 ! neurotransmitter transport GO:0006836 123 74 0,000 0,19092912 0,19766586 ! meiosis GO:0007126 121 74 0,000 0,19092912 0,19758084 GO:0051327|M phase of meiotic cell cycle, ! exocytosis GO:0006887 133 74 0,000 0,19092912 0,1974959 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,19092912 0,19741103 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,19092912 0,19732623 ! organelle localization GO:0051640 136 74 0,000 0,19092912 0,1972415 ! cell-matrix adhesion GO:0007160 163 75 0,000 0,19324514 0,19954841 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,19324514 0,1994628 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,19324514 0,19937727 ! meiotic cell cycle GO:0051321 122 75 0,000 0,19324514 0,19929181 ! rhythmic process GO:0048511 128 75 0,000 0,19324514 0,19920642 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,1955546 0,2015008 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,1955546 0,20141454 ! defense response to bacterium GO:0042742 89 76 0,000 0,1955546 0,20132836 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,1955546 0,20124224 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,1955546 0,20115621 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,19785753 0,20343813 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,19785753 0,20335122 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,19785753 0,2032644 ! blood coagulation GO:0007596 146 78 0,000 0,20015394 0,2055358 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,20015394 0,20544812 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,20015394 0,20536051 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,20244386 0,20762145 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,20244386 0,20753299 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 0,000 0,20244386 0,2074446 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,20244386 0,20735629 ! response to metal ion GO:0010038 140 80 0,000 0,20472729 0,2096059 ! muscle cell differentiation GO:0042692 159 80 0,000 0,20472729 0,20951674 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,20472729 0,20942766 ! inorganic anion transport GO:0015698 138 80 0,000 0,20472729 0,20933866 ! digestion GO:0007586 112 81 0,000 0,20700427 0,211577 ! cell-substrate adhesion GO:0031589 171 81 0,000 0,20700427 0,21148716 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,20700427 0,2113974 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,20700427 0,21130771 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,2092748 0,21353484 ! response to nutrient GO:0007584 125 82 0,000 0,2092748 0,21344432 ! hemostasis GO:0007599 158 84 0,000 0,2137966 0,21796382 ! negative regulation of transport GO:0051051 153 84 0,000 0,2137966 0,2178715 ! regulation of ligase activity GO:0051340 142 84 0,000 0,2137966 0,21777926 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,2137966 0,2176871 ! response to unfolded protein GO:0006986 131 85 0,000 0,2160479 0,21988632 ! nucleosome assembly GO:0006334 122 85 0,000 0,2160479 0,21979334 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,2160479 0,21970045 ! amine biosynthetic process GO:0009309 138 86 0,000 0,21829284 0,22188955 ! response to inorganic substance GO:0010035 153 86 0,000 0,21829284 0,22179585 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,21829284 0,22170222 ! chromatin assembly GO:0031497 124 86 0,000 0,21829284 0,22160868 ! alcohol catabolic process GO:0046164 130 86 0,000 0,21829284 0,22151521 ! amine transport GO:0015837 155 86 0,000 0,21829284 0,22142182 ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,22053142 0,22359823 ! cellular respiration GO:0045333 135 88 0,000 0,22276366 0,22576637 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,22276366 0,22567131 ! cellular defense response GO:0006968 114 89 0,000 0,22498959 0,22783037 ! regulation of cell morphogenesis GO:0022604 215 89 0,000 0,22498959 0,22773452 ! regulation of cell cycle process GO:0010564 149 90 0,000 0,22720921 0,22988451 ! sex differentiation GO:0007548 145 90 0,000 0,22720921 0,22978788 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,22720921 0,22969133 ! sterol metabolic process GO:0016125 152 91 0,000 0,22942256 0,23183144 ! response to protein stimulus GO:0051789 149 91 0,000 0,22942256 0,23173412 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,22942256 0,23163687 ! regulation of defense response GO:0031347 149 92 0,000 0,23162963 0,23376715 ! nucleosome organization GO:0034728 138 92 0,000 0,23162963 0,23366914 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,23162963 0,2335712 ! vitamin metabolic process GO:0006766 139 92 0,000 0,23162963 0,23347335 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,23383046 0,235593 GO:0010498|proteasomal protein catabolic process, ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,23383046 0,23549438 ! negative regulation of multicellular organismal process GO:0051241 166 93 0,000 0,23383046 0,23539585 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,23602506 0,23750576 ! female pregnancy GO:0007565 164 94 0,000 0,23602506 0,23740647 ! transcription initiation GO:0006352 153 94 0,000 0,23602506 0,23730726 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,23821344 0,23940749 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,24039563 0,24149974 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,24039563 0,24139895 ! positive regulation of immune response GO:0050778 156 96 0,000 0,24039563 0,24129824 ! detection of stimulus GO:0051606 151 96 0,000 0,24039563 0,24119761 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,24257164 0,24327943 ! protein ubiquitination GO:0016567 217 97 0,000 0,24257164 0,24317807 ! hormone metabolic process GO:0042445 157 97 0,000 0,24257164 0,24307678 ! response to virus GO:0009615 160 98 0,000 0,24474148 0,24514905 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,24474148 0,24504703 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,24474148 0,2449451 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,24690519 0,24700785 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,24690519 0,24690519