pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6780-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! induction of apoptosis by intracellular signals GO:0008629 93 45 7,000 1,548E-12 3,724E-09 ! male meiosis GO:0007140 7 6 3,000 1,447E-09 1,741E-06 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 3,000 3,368E-09 2,701E-06 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 3,000 6,719E-09 4,041E-06 GO:0016446|somatic hypermutation of immunoglobulin genes, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 4,000 1,496E-08 7,199E-06 ! response to UV GO:0009411 104 53 5,000 1,821E-08 7,303E-06 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 3,000 2,006E-08 6,894E-06 ! mismatch repair GO:0006298 46 34 4,000 7,659E-08 2,304E-05 ! negative regulation of DNA metabolic process GO:0051053 61 35 4,000 8,913E-08 2,383E-05 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 3,000 3,622E-07 8,713E-05 ! somatic diversification of immunoglobulins GO:0016445 50 22 3,000 6,785E-07 1,484E-04 ! regulation of DNA metabolic process GO:0051052 178 97 5,000 7,004E-07 1,404E-04 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 3,000 9,808E-07 1,815E-04 GO:0016444|somatic cell DNA recombination, ! negative regulation of phosphorylation GO:0042326 47 24 3,000 9,808E-07 1,686E-04 ! regulation of helicase activity GO:0051095 15 7 2,000 1,088E-06 1,746E-04 ! negative regulation of DNA recombination GO:0045910 15 7 2,000 1,088E-06 1,637E-04 ! immunoglobulin production GO:0002377 55 25 3,000 1,165E-06 1,648E-04 GO:0002440|production of molecular mediator of immune response, ! negative regulation of phosphorus metabolic process GO:0010563 51 26 3,000 1,373E-06 1,835E-04 GO:0045936|negative regulation of phosphate metabolic process, ! somatic diversification of immune receptors GO:0002200 56 26 3,000 1,373E-06 1,739E-04 ! DNA damage response, signal transduction GO:0042770 128 60 4,000 1,408E-06 1,694E-04 ! protein amino acid autophosphorylation GO:0046777 141 60 4,000 1,408E-06 1,613E-04 ! negative regulation of protein kinase activity GO:0006469 130 67 4,000 2,447E-06 2,676E-04 ! induction of positive chemotaxis GO:0050930 15 9 2,000 2,6E-06 2,72E-04 ! mitochondrion localization GO:0051646 15 9 2,000 2,6E-06 2,606E-04 ! negative regulation of kinase activity GO:0033673 131 68 4,000 2,634E-06 2,535E-04 ! negative regulation of transferase activity GO:0051348 140 72 4,000 3,5E-06 3,239E-04 ! multicellular organism growth GO:0035264 18 10 2,000 3,706E-06 3,302E-04 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 2,000 3,706E-06 3,184E-04 ! meiosis GO:0007126 121 74 4,000 4,01E-06 3,327E-04 GO:0051327|M phase of meiotic cell cycle, ! meiotic cell cycle GO:0051321 122 75 4,000 4,285E-06 3,437E-04 ! regulation of catabolic process GO:0009894 161 76 4,000 4,575E-06 3,551E-04 ! chondrocyte differentiation GO:0002062 24 11 2,000 5,083E-06 3,822E-04 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 2,000 5,083E-06 3,706E-04 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! negative regulation of glucose import GO:0046325 17 11 2,000 5,083E-06 3,597E-04 GO:0010829|negative regulation of glucose transport, ! meiosis I GO:0007127 65 37 3,000 5,905E-06 4,06E-04 ! regulation of positive chemotaxis GO:0050926 19 12 2,000 6,762E-06 4,519E-04 GO:0050927|positive regulation of positive chemotaxis, ! immunoglobulin production during immune response GO:0002381 23 12 2,000 6,762E-06 4,397E-04 ! negative regulation of transport GO:0051051 153 84 4,000 7,493E-06 4,745E-04 ! response to X-ray GO:0010165 25 13 2,000 8,771E-06 5,411E-04 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 2,000 1,114E-05 6,699E-04 ! actin cytoskeleton reorganization GO:0031532 33 14 2,000 1,114E-05 6,535E-04 ! response to gamma radiation GO:0010332 28 14 2,000 1,114E-05 6,38E-04 ! double-strand break repair GO:0006302 81 44 3,000 1,193E-05 6,677E-04 ! regulation of the force of heart contraction GO:0002026 26 15 2,000 1,389E-05 7,595E-04 ! regulation of inflammatory response GO:0050727 75 48 3,000 1,694E-05 9,056E-04 ! induction of apoptosis by extracellular signals GO:0008624 89 49 3,000 1,84E-05 9,623E-04 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 2,000 2,066E-05 1,058E-03 ! neutrophil chemotaxis GO:0030593 27 17 2,000 2,066E-05 1,036E-03 ! regulation of protein catabolic process GO:0042176 116 55 3,000 2,919E-05 1,433E-03 ! aging GO:0007568 103 55 3,000 2,919E-05 1,404E-03 ! regulation of DNA replication GO:0006275 101 56 3,000 3,135E-05 1,479E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 2,000 3,44E-05 1,592E-03 ! regulation of glucose import GO:0046324 29 20 2,000 3,44E-05 1,562E-03 GO:0010827|regulation of glucose transport, ! reciprocal meiotic recombination GO:0007131 39 21 2,000 4,004E-05 1,784E-03 ! inactivation of MAPK activity GO:0000188 39 21 2,000 4,004E-05 1,751E-03 ! cell aging GO:0007569 44 21 2,000 4,004E-05 1,72E-03 ! oogenesis GO:0048477 36 21 2,000 4,004E-05 1,69E-03 ! positive regulation of locomotion GO:0040017 39 21 2,000 4,004E-05 1,661E-03 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! positive regulation of inflammatory response GO:0050729 35 21 2,000 4,004E-05 1,633E-03 ! negative regulation of response to stimulus GO:0048585 100 60 3,000 4,122E-05 1,653E-03 ! regulation of chemotaxis GO:0050920 40 22 2,000 4,625E-05 1,824E-03 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 2,000 4,625E-05 1,795E-03 ! regulation of DNA recombination GO:0000018 48 23 2,000 5,307E-05 2,027E-03 ! regulation of behavior GO:0050795 43 24 2,000 6,051E-05 2,275E-03 ! protein tetramerization GO:0051262 52 24 2,000 6,051E-05 2,24E-03 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 3,000 6,37E-05 2,322E-03 ! negative regulation of DNA replication GO:0008156 42 25 2,000 6,86E-05 2,464E-03 ! response to endoplasmic reticulum stress GO:0034976 43 25 2,000 6,86E-05 2,427E-03 ! insulin receptor signaling pathway GO:0008286 64 26 2,000 7,737E-05 2,698E-03 ! B cell activation GO:0042113 160 71 3,000 7,997E-05 2,749E-03 ! regulation of fibroblast proliferation GO:0048145 52 27 2,000 8,684E-05 2,943E-03 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 2,000 8,684E-05 2,902E-03 ! organelle localization GO:0051640 136 74 3,000 9,401E-05 3,099E-03 ! negative regulation of protein modification process GO:0031400 60 28 2,000 9,704E-05 3,155E-03 ! ER-nuclear signaling pathway GO:0006984 48 28 2,000 9,704E-05 3,113E-03 ! positive regulation of helicase activity GO:0051096 11 5 1,000 9,992E-05 3,163E-03 ! female meiosis GO:0007143 7 5 1,000 9,992E-05 3,122E-03 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 1,000 9,992E-05 3,082E-03 ! positive regulation of glycolysis GO:0045821 14 5 1,000 9,992E-05 3,043E-03 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 1,000 9,992E-05 3,005E-03 ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 9,992E-05 2,968E-03 ! peptidyl-histidine phosphorylation GO:0018106 9 5 1,000 9,992E-05 2,932E-03 ! early endosome to late endosome transport GO:0045022 12 5 1,000 9,992E-05 2,897E-03 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 1,000 9,992E-05 2,862E-03 ! meiotic chromosome segregation GO:0045132 7 5 1,000 9,992E-05 2,828E-03 ! metaphase plate congression GO:0051310 7 5 1,000 9,992E-05 2,796E-03 ! glial cell migration GO:0008347 11 5 1,000 9,992E-05 2,763E-03 ! inner cell mass cell proliferation GO:0001833 5 5 1,000 9,992E-05 2,732E-03 ! spindle assembly GO:0051225 6 5 1,000 9,992E-05 2,701E-03 ! cellular response to extracellular stimulus GO:0031668 48 29 2,000 1,08E-04 2,887E-03 ! positive regulation of phosphorylation GO:0042327 129 79 3,000 1,213E-04 3,206E-03 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 3,000 1,336E-04 3,495E-03 GO:0045937|positive regulation of phosphate metabolic process, ! response to ionizing radiation GO:0010212 65 32 2,000 1,456E-04 3,766E-03 ! negative regulation of MAP kinase activity GO:0043407 69 32 2,000 1,456E-04 3,726E-03 ! positive regulation of catabolic process GO:0009896 64 32 2,000 1,456E-04 3,687E-03 ! male sex determination GO:0030238 15 6 1,000 1,496E-04 3,749E-03 ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 1,000 1,496E-04 3,71E-03 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! response to UV-C GO:0010225 11 6 1,000 1,496E-04 3,672E-03 ! negative regulation of neuroblast proliferation GO:0007406 21 6 1,000 1,496E-04 3,635E-03 ! determination of adult lifespan GO:0008340 15 6 1,000 1,496E-04 3,599E-03 ! leukocyte chemotaxis GO:0030595 50 33 2,000 1,598E-04 3,806E-03 GO:0060326|cell chemotaxis, ! negative regulation of protein transport GO:0051224 69 33 2,000 1,598E-04 3,768E-03 ! mitochondrion organization GO:0007005 148 86 3,000 1,685E-04 3,936E-03 ! cytokinesis during cell cycle GO:0033205 11 7 1,000 2,09E-04 4,834E-03 ! prostate gland development GO:0030850 13 7 1,000 2,09E-04 4,788E-03 ! synaptonemal complex assembly GO:0007130 10 7 1,000 2,09E-04 4,743E-03 GO:0070193|synaptonemal complex organization, ! regulation of protein export from nucleus GO:0046825 10 7 1,000 2,09E-04 4,699E-03 ! N-terminal protein amino acid acetylation GO:0006474 13 7 1,000 2,09E-04 4,655E-03 ! positive regulation of mitotic cell cycle GO:0045931 12 7 1,000 2,09E-04 4,613E-03 ! centrosome duplication GO:0051298 13 7 1,000 2,09E-04 4,571E-03 ! G1 DNA damage checkpoint GO:0031571 21 7 1,000 2,09E-04 4,53E-03 ! B cell lineage commitment GO:0002326 21 7 1,000 2,09E-04 4,489E-03 ! T cell lineage commitment GO:0002360 16 7 1,000 2,09E-04 4,449E-03 ! response to tumor cell GO:0002347 13 7 1,000 2,09E-04 4,41E-03 ! regulation of respiratory burst GO:0060263 11 7 1,000 2,09E-04 4,372E-03 ! peptidyl-histidine modification GO:0018202 16 7 1,000 2,09E-04 4,334E-03 ! axonal fasciculation GO:0007413 18 7 1,000 2,09E-04 4,297E-03 ! regulation of defense response GO:0031347 149 92 3,000 2,185E-04 4,456E-03 ! cellular response to insulin stimulus GO:0032869 82 37 2,000 2,254E-04 4,558E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 2,78E-04 5,575E-03 ! meiotic prophase I GO:0007128 13 8 1,000 2,78E-04 5,529E-03 ! endothelial cell differentiation GO:0045446 17 8 1,000 2,78E-04 5,483E-03 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 2,78E-04 5,439E-03 ! ER overload response GO:0006983 12 8 1,000 2,78E-04 5,395E-03 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 1,000 2,78E-04 5,352E-03 ! multicellular organismal aging GO:0010259 18 8 1,000 2,78E-04 5,309E-03 ! establishment of chromosome localization GO:0051303 12 8 1,000 2,78E-04 5,268E-03 GO:0050000|chromosome localization, ! blastocyst growth GO:0001832 19 8 1,000 2,78E-04 5,226E-03 ! cell cycle arrest GO:0007050 213 100 3,000 3,008E-04 5,609E-03 ! female gamete generation GO:0007292 61 41 2,000 3,064E-04 5,671E-03 ! regulation of intracellular protein transport GO:0033157 80 42 2,000 3,292E-04 6,047E-03 ! positive regulation of response to external stimulus GO:0032103 77 43 2,000 3,531E-04 6,436E-03 ! regulation of epithelial cell proliferation GO:0050678 111 43 2,000 3,531E-04 6,388E-03 ! regulation of developmental growth GO:0048638 15 9 1,000 3,567E-04 6,405E-03 ! axon extension GO:0048675 15 9 1,000 3,567E-04 6,358E-03 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 3,567E-04 6,311E-03 ! regulation of glycolysis GO:0006110 21 9 1,000 3,567E-04 6,265E-03 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 1,000 3,567E-04 6,22E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 1,000 3,567E-04 6,175E-03 ! receptor clustering GO:0043113 18 9 1,000 3,567E-04 6,131E-03 ! protein heterooligomerization GO:0051291 16 9 1,000 3,567E-04 6,087E-03 ! branched chain family amino acid catabolic process GO:0009083 17 9 1,000 3,567E-04 6,045E-03 ! leukocyte migration GO:0050900 68 45 2,000 4,041E-04 6,8E-03 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 2,000 4,313E-04 7,207E-03 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 2,000 4,313E-04 7,157E-03 ! regulation of gene-specific transcription GO:0032583 96 46 2,000 4,313E-04 7,108E-03 ! response to insulin stimulus GO:0032868 95 46 2,000 4,313E-04 7,06E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 1,000 4,45E-04 7,234E-03 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 4,45E-04 7,186E-03 ! synapsis GO:0007129 13 10 1,000 4,45E-04 7,138E-03 GO:0070192|chromosome organization involved in meiosis, ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 1,000 4,45E-04 7,091E-03 ! positive regulation of phagocytosis GO:0050766 13 10 1,000 4,45E-04 7,044E-03 ! prophase GO:0051324 15 10 1,000 4,45E-04 6,998E-03 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 1,000 4,45E-04 6,953E-03 GO:0043470|regulation of carbohydrate catabolic process, ! oocyte development GO:0048599 17 10 1,000 4,45E-04 6,908E-03 ! localization within membrane GO:0051668 20 10 1,000 4,45E-04 6,863E-03 ! positive regulation of defense response GO:0031349 76 47 2,000 4,597E-04 7,045E-03 ! positive regulation of cell cycle GO:0045787 89 48 2,000 4,892E-04 7,449E-03 ! immunoglobulin mediated immune response GO:0016064 83 49 2,000 5,199E-04 7,867E-03 GO:0019724|B cell mediated immunity, ! regulation of nitric-oxide synthase activity GO:0050999 26 11 1,000 5,428E-04 8,162E-03 ! peptide or protein amino-terminal blocking GO:0018409 21 11 1,000 5,428E-04 8,111E-03 ! regulation of intracellular pH GO:0051453 19 11 1,000 5,428E-04 8,061E-03 ! negative regulation of ossification GO:0030279 26 11 1,000 5,428E-04 8,012E-03 ! oocyte differentiation GO:0009994 18 11 1,000 5,428E-04 7,963E-03 ! regulation of embryonic development GO:0045995 27 11 1,000 5,428E-04 7,915E-03 ! response to estrogen stimulus GO:0043627 93 51 2,000 5,85E-04 8,478E-03 ! regulation of muscle contraction GO:0006937 81 52 2,000 6,193E-04 8,923E-03 ! cartilage development GO:0051216 90 52 2,000 6,193E-04 8,87E-03 ! positive regulation of cellular catabolic process GO:0031331 31 12 1,000 6,5E-04 9,253E-03 ! virus-host interaction GO:0019048 29 12 1,000 6,5E-04 9,199E-03 ! regulation of B cell proliferation GO:0030888 20 12 1,000 6,5E-04 9,145E-03 ! dopamine receptor signaling pathway GO:0007212 28 12 1,000 6,5E-04 9,092E-03 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 1,000 6,5E-04 9,039E-03 ! regulation of phagocytosis GO:0050764 16 12 1,000 6,5E-04 8,988E-03 ! histone acetylation GO:0016573 26 12 1,000 6,5E-04 8,936E-03 ! peptidyl-lysine modification GO:0018205 21 12 1,000 6,5E-04 8,885E-03 ! double-strand break repair via homologous recombination GO:0000724 19 13 1,000 7,666E-04 0,01041989 GO:0000725|recombinational repair, ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 1,000 7,666E-04 0,01036135 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of cellular pH GO:0030641 22 13 1,000 7,666E-04 0,01030347 ! regulation of monooxygenase activity GO:0032768 33 13 1,000 7,666E-04 0,01024623 ! cytoplasmic sequestering of protein GO:0051220 24 13 1,000 7,666E-04 0,01018962 ! nucleotide-excision repair GO:0006289 83 56 2,000 7,697E-04 0,01017545 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 2,000 8,106E-04 0,01065749 ! positive regulation of cell migration GO:0030335 126 57 2,000 8,106E-04 0,01059957 ! lipid modification GO:0030258 97 57 2,000 8,106E-04 0,01054227 ! regulation of intracellular transport GO:0032386 101 57 2,000 8,106E-04 0,01048559 ! N-terminal protein amino acid modification GO:0031365 27 14 1,000 8,925E-04 0,01148258 ! regulation of S phase GO:0033261 23 14 1,000 8,925E-04 0,0114215 ! non-recombinational repair GO:0000726 25 14 1,000 8,925E-04 0,01136107 GO:0006303|double-strand break repair via nonhomologous end joining, ! regulation of mRNA processing GO:0050684 24 14 1,000 8,925E-04 0,01130127 ! release of cytochrome c from mitochondria GO:0001836 30 14 1,000 8,925E-04 0,0112421 ! regulation of heart contraction GO:0008016 110 60 2,000 9,415E-04 0,01179807 ! response to peptide hormone stimulus GO:0043434 122 61 2,000 9,879E-04 0,01231565 ! negative regulation of bone remodeling GO:0046851 33 15 1,000 1,028E-03 0,01274456 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 1,000 1,028E-03 0,01267921 ! G1/S transition checkpoint GO:0031575 40 15 1,000 1,028E-03 0,01261452 ! regulation of ATPase activity GO:0043462 21 15 1,000 1,028E-03 0,01255049 ! lymphocyte mediated immunity GO:0002449 114 64 2,000 1,136E-03 0,01380164 ! positive regulation of cell motion GO:0051272 146 64 2,000 1,136E-03 0,01373228 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 1,172E-03 0,01409895 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 1,000 1,172E-03 0,01402881 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 1,000 1,172E-03 0,01395936 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! positive regulation of protein import into nucleus GO:0042307 30 16 1,000 1,172E-03 0,01389059 ! neuron recognition GO:0008038 35 16 1,000 1,172E-03 0,0138225 ! negative regulation of tissue remodeling GO:0034104 36 16 1,000 1,172E-03 0,01375507 ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 1,172E-03 0,0136883 ! negative regulation of cell growth GO:0030308 132 67 2,000 1,297E-03 0,0150747 ! lung development GO:0030324 144 67 2,000 1,297E-03 0,01500223 ! adaptive immune response GO:0002250 119 67 2,000 1,297E-03 0,01493045 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! signal complex assembly GO:0007172 41 17 1,000 1,325E-03 0,01518635 ! endothelial cell migration GO:0043542 28 17 1,000 1,325E-03 0,01511438 ! negative regulation of protein catabolic process GO:0042177 40 17 1,000 1,325E-03 0,01504309 ! branched chain family amino acid metabolic process GO:0009081 33 17 1,000 1,325E-03 0,01497246 ! negative regulation of cell size GO:0045792 134 69 2,000 1,412E-03 0,01587482 ! respiratory tube development GO:0030323 150 70 2,000 1,472E-03 0,01647059 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 1,488E-03 0,01657563 ! centrosome cycle GO:0007098 25 18 1,000 1,488E-03 0,01649925 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 1,000 1,488E-03 0,01642356 ! reproductive structure development GO:0048608 113 71 2,000 1,533E-03 0,01684437 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 2,000 1,596E-03 0,01745667 ! respiratory system development GO:0060541 153 72 2,000 1,596E-03 0,01737768 ! lipid phosphorylation GO:0046834 35 19 1,000 1,66E-03 0,01798765 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 1,000 1,66E-03 0,01790698 ! cellular response to unfolded protein GO:0034620 33 19 1,000 1,66E-03 0,01782704 GO:0030968|endoplasmic reticulum unfolded protein response, ! prostaglandin metabolic process GO:0006693 37 19 1,000 1,66E-03 0,01774781 GO:0006692|prostanoid metabolic process, ! regulation of transcription factor activity GO:0051090 126 74 2,000 1,727E-03 0,01838562 GO:0090046|regulation of transcription regulator activity, ! leukocyte mediated immunity GO:0002443 128 74 2,000 1,727E-03 0,01830462 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 1,000 1,84E-03 0,01941999 ! protein amino acid acetylation GO:0006473 39 20 1,000 1,84E-03 0,01933518 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 1,000 1,84E-03 0,01925112 ! regulation of carbohydrate metabolic process GO:0006109 38 20 1,000 1,84E-03 0,01916778 GO:0010675|regulation of cellular carbohydrate metabolic process, ! apoptotic mitochondrial changes GO:0008637 41 20 1,000 1,84E-03 0,01908516 ! cellular response to starvation GO:0009267 33 20 1,000 1,84E-03 0,01900325 ! fatty acid beta-oxidation GO:0006635 34 20 1,000 1,84E-03 0,01892204 ! sensory perception of pain GO:0019233 30 20 1,000 1,84E-03 0,01884152 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 1,000 1,84E-03 0,01876168 ! response to steroid hormone stimulus GO:0048545 137 78 2,000 2,008E-03 0,02038733 ! protein oligomerization GO:0051259 139 78 2,000 2,008E-03 0,02030167 ! cholesterol biosynthetic process GO:0006695 37 21 1,000 2,03E-03 0,02043388 ! negative regulation of intracellular transport GO:0032387 41 21 1,000 2,03E-03 0,02034874 ! positive regulation of protein catabolic process GO:0045732 38 22 1,000 2,228E-03 0,02224455 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 1,000 2,228E-03 0,02215263 ! positive regulation of intracellular transport GO:0032388 37 22 1,000 2,228E-03 0,02206147 ! positive regulation of B cell activation GO:0050871 38 22 1,000 2,228E-03 0,02197106 ! protein stabilization GO:0050821 39 22 1,000 2,228E-03 0,02188138 ! cellular response to hormone stimulus GO:0032870 167 82 2,000 2,316E-03 0,02265562 ! positive regulation of DNA replication GO:0045740 43 23 1,000 2,435E-03 0,02372204 ! sex determination GO:0007530 47 23 1,000 2,435E-03 0,02362638 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 1,000 2,435E-03 0,0235315 ! regulation of bone mineralization GO:0030500 49 23 1,000 2,435E-03 0,02343737 ! negative regulation of catabolic process GO:0009895 50 23 1,000 2,435E-03 0,023344 ! negative regulation of growth GO:0045926 155 84 2,000 2,481E-03 0,02368645 ! protein import into nucleus, translocation GO:0000060 46 24 1,000 2,651E-03 0,02521255 ! positive regulation of fibroblast proliferation GO:0048146 43 24 1,000 2,651E-03 0,02511329 ! regulation of cellular catabolic process GO:0031329 52 24 1,000 2,651E-03 0,02501481 ! regulation of oxidoreductase activity GO:0051341 46 24 1,000 2,651E-03 0,02491709 ! regulation of protein transport GO:0051223 154 87 2,000 2,741E-03 0,02565927 GO:0070201|regulation of establishment of protein localization, ! positive regulation of protein modification process GO:0031401 136 88 2,000 2,831E-03 0,02640132 ! regulation of DNA binding GO:0051101 155 88 2,000 2,831E-03 0,02629938 ! gland development GO:0048732 206 88 2,000 2,831E-03 0,02619823 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 1,000 2,876E-03 0,02650996 ! receptor metabolic process GO:0043112 46 25 1,000 2,876E-03 0,02640877 ! response to starvation GO:0042594 42 25 1,000 2,876E-03 0,02630836 ! negative regulation of cell development GO:0010721 73 25 1,000 2,876E-03 0,02620871 GO:0050768|negative regulation of neurogenesis, ! interaction with host GO:0051701 62 25 1,000 2,876E-03 0,02610981 ! regulation of biomineral formation GO:0070167 51 25 1,000 2,876E-03 0,02601165 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 1,000 2,876E-03 0,02591423 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 1,000 2,876E-03 0,02581753 ! cellular response to nutrient levels GO:0031669 41 25 1,000 2,876E-03 0,02572156 ! ossification GO:0001503 188 90 2,000 3,017E-03 0,02688469 ! sex differentiation GO:0007548 145 90 2,000 3,017E-03 0,02678548 ! regulation of transcription factor import into nucleus GO:0042990 54 26 1,000 3,109E-03 0,02750065 ! microtubule organizing center organization GO:0031023 39 26 1,000 3,109E-03 0,02739992 GO:0051297|centrosome organization, ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 1,000 3,109E-03 0,02729992 ! blastocyst development GO:0001824 49 26 1,000 3,109E-03 0,02720065 ! bone development GO:0060348 189 91 2,000 3,113E-03 0,02713457 ! positive regulation of MAP kinase activity GO:0043406 160 93 2,000 3,31E-03 0,0287475 ! protein amino acid acylation GO:0043543 55 27 1,000 3,351E-03 0,02899956 ! mitochondrial membrane organization GO:0007006 57 27 1,000 3,351E-03 0,02889562 ! base-excision repair GO:0006284 41 27 1,000 3,351E-03 0,02879242 ! interphase of mitotic cell cycle GO:0051329 209 95 2,000 3,514E-03 0,03008886 ! peptidyl-tyrosine modification GO:0018212 50 28 1,000 3,601E-03 0,03072362 ! lipid oxidation GO:0034440 43 28 1,000 3,601E-03 0,03061506 GO:0019395|fatty acid oxidation, ! regulation of protein localization GO:0032880 176 97 2,000 3,726E-03 0,03156723 ! interphase GO:0051325 213 98 2,000 3,835E-03 0,03237561 ! carboxylic acid catabolic process GO:0046395 156 98 2,000 3,835E-03 0,03226241 GO:0016054|organic acid catabolic process, ! regulation of pH GO:0006885 43 29 1,000 3,86E-03 0,03235749 ! respiratory gaseous exchange GO:0007585 57 29 1,000 3,86E-03 0,03224514 ! response to organic cyclic substance GO:0014070 55 29 1,000 3,86E-03 0,03213356 ! sterol biosynthetic process GO:0016126 52 29 1,000 3,86E-03 0,03202276 ! tissue homeostasis GO:0001894 48 29 1,000 3,86E-03 0,03191271 GO:0048871|multicellular organismal homeostasis, ! acute-phase response GO:0006953 49 30 1,000 4,127E-03 0,03400464 ! regulation of B cell activation GO:0050864 50 30 1,000 4,127E-03 0,03388859 ! fatty acid catabolic process GO:0009062 48 31 1,000 4,402E-03 0,03602789 ! negative regulation of transcription regulator activity GO:0090048 58 31 1,000 4,402E-03 0,03590576 GO:0043433|negative regulation of transcription factor activity, ! spindle organization GO:0007051 46 32 1,000 4,686E-03 0,0380912 ! regulation of protein import into nucleus GO:0042306 63 32 1,000 4,686E-03 0,03796295 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 1,000 4,686E-03 0,03783556 ! peripheral nervous system development GO:0007422 64 32 1,000 4,686E-03 0,03770902 ! DNA damage checkpoint GO:0000077 71 33 1,000 4,978E-03 0,03992539 ! post-embryonic development GO:0009791 69 33 1,000 4,978E-03 0,03979275 ! positive regulation of gene-specific transcription GO:0043193 65 33 1,000 4,978E-03 0,03966099 ! positive regulation of endocytosis GO:0045807 50 34 1,000 5,278E-03 0,04191397 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 1,000 5,278E-03 0,04177609 ! female gonad development GO:0008585 58 35 1,000 5,587E-03 0,04407151 ! negative regulation of hydrolase activity GO:0051346 62 35 1,000 5,587E-03 0,04392748 ! calcium-mediated signaling GO:0019722 62 35 1,000 5,587E-03 0,0437844 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 1,000 5,903E-03 0,04611403 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! maintenance of protein location in cell GO:0032507 86 36 1,000 5,903E-03 0,04596479 ! DNA integrity checkpoint GO:0031570 75 36 1,000 5,903E-03 0,04581652 ! monovalent inorganic cation homeostasis GO:0055067 58 37 1,000 6,228E-03 0,04817921 ! negative regulation of DNA binding GO:0043392 68 37 1,000 6,228E-03 0,04802479 ! regulation of protein stability GO:0031647 73 37 1,000 6,228E-03 0,04787136 ! positive regulation of DNA metabolic process GO:0051054 72 38 1,000 6,56E-03 0,05026601 ! mitotic cell cycle checkpoint GO:0007093 76 38 1,000 6,56E-03 0,05010644 ! carbohydrate homeostasis GO:0033500 53 38 1,000 6,56E-03 0,04994787 GO:0042593|glucose homeostasis, ! development of primary female sexual characteristics GO:0046545 67 38 1,000 6,56E-03 0,04979031 GO:0046660|female sex differentiation, ! positive regulation of leukocyte proliferation GO:0070665 62 38 1,000 6,56E-03 0,04963373 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! mRNA catabolic process GO:0006402 71 39 1,000 6,9E-03 0,05204504 ! mammary gland development GO:0030879 86 39 1,000 6,9E-03 0,0518824 ! segmentation GO:0035282 67 39 1,000 6,9E-03 0,05172077 ! negative regulation of binding GO:0051100 72 40 1,000 7,249E-03 0,0541619 ! maintenance of protein location GO:0045185 91 40 1,000 7,249E-03 0,05399422 ! cytokinesis GO:0000910 72 40 1,000 7,249E-03 0,05382757 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 1,000 7,605E-03 0,05629751 ! gliogenesis GO:0042063 88 41 1,000 7,605E-03 0,05612482 ! T cell differentiation GO:0030217 81 41 1,000 7,605E-03 0,05595318 ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 7,968E-03 0,05845097 GO:0090047|positive regulation of transcription regulator activity, ! neuron migration GO:0001764 79 42 1,000 7,968E-03 0,05827331 ! B cell differentiation GO:0030183 107 44 1,000 8,719E-03 0,06356935 ! developmental growth GO:0048589 82 44 1,000 8,719E-03 0,0633773 ! maintenance of location in cell GO:0051651 97 44 1,000 8,719E-03 0,0631864 ! icosanoid metabolic process GO:0006690 80 45 1,000 9,106E-03 0,06579092 ! cell growth GO:0016049 84 45 1,000 9,106E-03 0,06559394 ! positive regulation of protein transport GO:0051222 72 46 1,000 9,5E-03 0,06822997 ! endosome transport GO:0016197 108 47 1,000 9,902E-03 0,07090402 ! positive regulation of DNA binding GO:0043388 73 47 1,000 9,902E-03 0,07069362 ! JNK cascade GO:0007254 91 47 1,000 9,902E-03 0,07048447 ! mitochondrial transport GO:0006839 82 48 1,000 0,01031105 0,0731811 ! activation of caspase activity GO:0006919 84 48 1,000 0,01031105 0,07296586 ! regulation of mast cell proliferation GO:0070666 81 48 1,000 0,01031105 0,07275188 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 1,000 0,0107277 0,07547029 ! unsaturated fatty acid metabolic process GO:0033559 86 49 1,000 0,0107277 0,07525026 ! DNA-dependent DNA replication GO:0006261 74 49 1,000 0,0107277 0,07503151 ! regulation of ossification GO:0030278 117 50 1,000 0,01115169 0,07777093 ! histone modification GO:0016570 91 50 1,000 0,01115169 0,07754616 ! positive regulation of binding GO:0051099 78 51 1,000 0,01158299 0,08031316 ! regulation of leukocyte proliferation GO:0070663 88 51 1,000 0,01158299 0,08008238 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! positive regulation of growth GO:0045927 90 52 1,000 0,01202153 0,08287624 ! covalent chromatin modification GO:0016569 101 52 1,000 0,01202153 0,08263945 ! amino acid activation GO:0043038 92 52 1,000 0,01202153 0,08240401 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! RNA catabolic process GO:0006401 93 53 1,000 0,01246728 0,08521669 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 1,000 0,01246728 0,08497528 ! cell maturation GO:0048469 100 53 1,000 0,01246728 0,08473524 ! regulation of neuron apoptosis GO:0043523 100 53 1,000 0,01246728 0,08449655 ! activation of phospholipase C activity GO:0007202 103 54 1,000 0,01292018 0,08732008 GO:0010863|positive regulation of phospholipase C activity, ! cell recognition GO:0008037 85 54 1,000 0,01292018 0,08707549 ! positive regulation of caspase activity GO:0043280 95 55 1,000 0,01338018 0,08992377 GO:0010952|positive regulation of peptidase activity, ! positive regulation of phospholipase activity GO:0010518 104 55 1,000 0,01338018 0,08967329 ! heart morphogenesis GO:0003007 97 55 1,000 0,01338018 0,0894242 ! regulation of bone remodeling GO:0046850 137 57 1,000 0,01432129 0,09544883 ! regulation of phospholipase activity GO:0010517 106 57 1,000 0,01432129 0,09518516 ! maintenance of location GO:0051235 118 57 1,000 0,01432129 0,09492295 ! regulation of tissue remodeling GO:0034103 140 58 1,000 0,01480231 0,09784163 ! regulation of endocytosis GO:0030100 91 58 1,000 0,01480231 0,09757357 ! positive regulation of lipase activity GO:0060193 108 58 1,000 0,01480231 0,09730697 ! establishment of organelle localization GO:0051656 109 59 1,000 0,01529023 0,10024059 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,0158376 0,10354695 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,0158376 0,10326633 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,0158376 0,10298724 ! neuron fate determination GO:0048664 7 5 0,000 0,0158376 0,10270964 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,0158376 0,10243354 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,0158376 0,10215892 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,0158376 0,10188577 ! polyol transport GO:0015791 12 5 0,000 0,0158376 0,10161407 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,0158376 0,10134382 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,0158376 0,10107501 ! response to superoxide GO:0000303 10 5 0,000 0,0158376 0,10080761 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,0158376 0,10054163 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,0158376 0,10027705 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,0158376 0,10001385 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,0158376 0,09975204 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,0158376 0,09949159 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,0158376 0,09923249 ! cobalt ion transport GO:0006824 11 5 0,000 0,0158376 0,09897475 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,0158376 0,09871834 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,0158376 0,09846325 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,0158376 0,09820948 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,0158376 0,09795701 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,0158376 0,09770584 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,0158376 0,09745595 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,0158376 0,09720734 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,0158376 0,09695999 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,0158376 0,0967139 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,0158376 0,09646906 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,0158376 0,09622545 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,0158376 0,09598307 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,0158376 0,0957419 ! negative chemotaxis GO:0050919 14 5 0,000 0,0158376 0,09550195 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,0158376 0,09526319 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,0158376 0,09502563 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,0158376 0,09478925 ! behavioral response to pain GO:0048266 9 5 0,000 0,0158376 0,09455404 ! clathrin coat assembly GO:0048268 14 5 0,000 0,0158376 0,09431999 ! Notch receptor processing GO:0007220 8 5 0,000 0,0158376 0,0940871 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,0158376 0,09385536 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,0158376 0,09362476 ! micturition GO:0060073 9 5 0,000 0,0158376 0,09339529 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,0158376 0,09316694 ! copulation GO:0007620 9 5 0,000 0,0158376 0,0929397 ! glial cell fate commitment GO:0021781 13 5 0,000 0,0158376 0,09271357 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,0158376 0,09248854 ! spermidine metabolic process GO:0008216 7 5 0,000 0,0158376 0,09226459 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,0158376 0,09204173 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,0158376 0,09181995 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,0158376 0,09159922 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,0158376 0,09137956 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,0158376 0,09116095 ! grooming behavior GO:0007625 6 5 0,000 0,0158376 0,09094338 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,0158376 0,09072685 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,0158376 0,09051135 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,0158376 0,09029687 ! response to protozoan GO:0001562 10 5 0,000 0,0158376 0,0900834 ! lymph vessel development GO:0001945 10 5 0,000 0,0158376 0,08987094 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,0158376 0,08965948 ! endochondral ossification GO:0001958 16 5 0,000 0,0158376 0,08944901 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,0158376 0,08923953 ! parathyroid gland development GO:0060017 13 5 0,000 0,0158376 0,08903102 ! anagen GO:0042640 6 5 0,000 0,0158376 0,08882349 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,0158376 0,08861692 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,0158376 0,08841132 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,0158376 0,08820666 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,0158376 0,08800295 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,0158376 0,08780018 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,0158376 0,08759834 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,0158376 0,08739743 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,0158376 0,08719743 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,0158376 0,08699835 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,0158376 0,08680018 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,0158376 0,0866029 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,0158376 0,08640652 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,0158376 0,08621103 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,0158376 0,08601643 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,0158376 0,0858227 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,0158376 0,08562984 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 0,0158376 0,08543784 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,0158376 0,08524671 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,0158376 0,08505642 ! histidine catabolic process GO:0006548 6 5 0,000 0,0158376 0,08486699 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,0158376 0,08467839 ! microvillus organization GO:0032528 7 5 0,000 0,0158376 0,08449064 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 0,0158376 0,08430371 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,0158376 0,08411761 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,0158376 0,08393233 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,0158376 0,08374786 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,0158376 0,0835642 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,0158376 0,08338135 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,0158376 0,0831993 ! polyol catabolic process GO:0046174 7 5 0,000 0,0158376 0,08301803 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,0158376 0,08283756 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,0158376 0,08265787 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,0158376 0,08247896 ! muscle cell migration GO:0014812 8 5 0,000 0,0158376 0,08230082 ! mitochondrial fission GO:0000266 8 5 0,000 0,0158376 0,08212344 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,0158376 0,08194683 ! mRNA transcription GO:0009299 9 5 0,000 0,0158376 0,08177098 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,0158376 0,08159588 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,0158376 0,08142153 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,0158376 0,08124793 GO:0051489|regulation of filopodium assembly, ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,0158376 0,08107506 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,0158376 0,08090292 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,0158376 0,08073152 ! response to food GO:0032094 6 5 0,000 0,0158376 0,08056084 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,0158376 0,08039088 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,0158376 0,08022164 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,0158376 0,0800531 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,0158376 0,07988528 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,0158376 0,07971815 ! forebrain neuron development GO:0021884 13 5 0,000 0,0158376 0,07955173 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,0158376 0,07938599 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,0158376 0,07922095 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,0158376 0,07905659 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,0158376 0,07889291 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,0158376 0,07872991 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,0158376 0,07856758 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,0158376 0,07840592 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,0158376 0,07824492 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,0158376 0,07808458 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,0158376 0,0779249 ! basic amino acid transport GO:0015802 11 5 0,000 0,0158376 0,07776587 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,0158376 0,07760749 ! depyrimidination GO:0045008 10 5 0,000 0,0158376 0,07744975 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,0158376 0,07729265 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,0158376 0,07713619 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,0158376 0,07698036 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,0158376 0,07682516 GO:0006882|cellular zinc ion homeostasis, ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,0158376 0,07667058 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,0158376 0,07651662 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,0158376 0,07636328 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,0158376 0,07621055 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,0158376 0,07605844 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,0158376 0,07590693 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,0158376 0,07575602 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,0158376 0,07560571 ! response to arsenic GO:0046685 10 5 0,000 0,0158376 0,07545599 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,0158376 0,07530687 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,0158376 0,07515834 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,0158376 0,07501039 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,0158376 0,07486302 ! response to cadmium ion GO:0046686 7 5 0,000 0,0158376 0,07471623 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,0158376 0,07457001 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,0158376 0,07442437 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,0158376 0,07427929 ! decidualization GO:0046697 11 5 0,000 0,0158376 0,07413478 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,0158376 0,07399083 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,0158376 0,07384744 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,0158376 0,0737046 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,0158376 0,07356231 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,0158376 0,07342057 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,0158376 0,07327938 ! neural tube patterning GO:0021532 7 5 0,000 0,0158376 0,07313873 ! embryonic cleavage GO:0040016 6 5 0,000 0,0158376 0,07299862 ! peroxisome fission GO:0016559 5 5 0,000 0,0158376 0,07285904 ! histone demethylation GO:0016577 10 5 0,000 0,0158376 0,07272 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,0158376 0,07258148 ! mitotic recombination GO:0006312 9 5 0,000 0,0158376 0,07244349 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,0158376 0,07230603 ! regulation of sterol transport GO:0032371 7 5 0,000 0,0158376 0,07216909 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,0158376 0,07203266 ! enteric nervous system development GO:0048484 8 5 0,000 0,0158376 0,07189675 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,0158376 0,07176135 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,0158376 0,07162646 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,0158376 0,07149208 ! muscle cell proliferation GO:0033002 11 5 0,000 0,0158376 0,0713582 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,0158376 0,07122482 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,0158376 0,07109194 ! plasminogen activation GO:0031639 5 5 0,000 0,0158376 0,07095955 ! B cell homeostasis GO:0001782 13 5 0,000 0,0158376 0,07082765 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,0158376 0,07069625 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,0158376 0,07056533 ! metaphase GO:0051323 8 5 0,000 0,0158376 0,07043489 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,0158376 0,07030494 ! cellular response to nutrient GO:0031670 8 5 0,000 0,0158376 0,07017546 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,0158376 0,07004647 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,0158376 0,06991794 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,0158376 0,06978989 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,0158376 0,0696623 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,0158376 0,06953518 ! response to redox state GO:0051775 5 5 0,000 0,0158376 0,06940852 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,0158376 0,06928232 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,0158376 0,06915658 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,0158376 0,0690313 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,0158376 0,06890647 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,0158376 0,06878209 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,0158376 0,06865816 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,0158376 0,06853467 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,0158376 0,06841163 ! striatum development GO:0021756 9 5 0,000 0,0158376 0,06828903 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,0158376 0,06816686 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,0158376 0,06804514 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,0158376 0,06792385 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,0158376 0,06780298 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,0158376 0,06768255 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,0158376 0,06756255 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,0158376 0,06744297 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,0158376 0,06732381 ! neuroprotection GO:0043526 6 5 0,000 0,0158376 0,06720507 ! neural plate development GO:0001840 8 5 0,000 0,0158376 0,06708676 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,0158376 0,06696885 ! regulation of sensory perception GO:0051931 7 5 0,000 0,0158376 0,06685136 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,0158376 0,06673429 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,0158376 0,06661762 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,0158376 0,06650136 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,0158376 0,0663855 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,0158376 0,06627005 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,0158376 0,066155 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,0158376 0,06604034 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,0158376 0,06592609 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,0158376 0,06581222 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,0158376 0,06569875 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,0158376 0,06558568 ! drug metabolic process GO:0017144 6 5 0,000 0,0158376 0,06547299 ! stem cell division GO:0017145 11 5 0,000 0,0158376 0,06536068 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,0158376 0,06524876 ! organ regeneration GO:0031100 7 5 0,000 0,0158376 0,06513723 ! carnitine metabolic process GO:0009437 7 5 0,000 0,0158376 0,06502607 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,0158376 0,06491529 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,0158376 0,06480489 ! tRNA processing GO:0008033 89 61 1,000 0,01628661 0,06652901 ! viral reproductive process GO:0022415 126 62 1,000 0,01679497 0,06848934 ! gonad development GO:0008406 98 62 1,000 0,01679497 0,06837345 ! nucleoside monophosphate metabolic process GO:0009123 107 63 1,000 0,01731005 0,07035133 ! cellular amino acid catabolic process GO:0009063 101 63 1,000 0,01731005 0,0702327 ! germ cell development GO:0007281 118 65 1,000 0,01836018 0,07436799 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 1,000 0,01889513 0,07640619 ! actin filament organization GO:0007015 148 66 1,000 0,01889513 0,07627799 ! developmental maturation GO:0021700 116 66 1,000 0,01889513 0,07615022 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,01897521 0,07634508 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,01897521 0,07621762 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,01897521 0,0760906 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,01897521 0,07596399 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,01897521 0,0758378 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,01897521 0,07571204 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,01897521 0,07558668 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,01897521 0,07546175 ! sleep GO:0030431 13 6 0,000 0,01897521 0,07533722 ! response to oxygen radical GO:0000305 11 6 0,000 0,01897521 0,07521311 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,01897521 0,0750894 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,01897521 0,0749661 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,01897521 0,07484321 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,01897521 0,07472072 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,01897521 0,07459862 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,01897521 0,07447693 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,01897521 0,07435563 ! forebrain regionalization GO:0021871 8 6 0,000 0,01897521 0,07423473 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,01897521 0,07411422 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,01897521 0,0739941 ! response to zinc ion GO:0010043 9 6 0,000 0,01897521 0,07387436 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,01897521 0,07375502 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,01897521 0,07363606 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,01897521 0,07351748 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,01897521 0,07339929 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,01897521 0,07328147 ! malate metabolic process GO:0006108 11 6 0,000 0,01897521 0,07316403 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,01897521 0,07304697 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,01897521 0,07293028 ! protein refolding GO:0042026 15 6 0,000 0,01897521 0,07281397 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,01897521 0,07269802 ! opsonization GO:0008228 8 6 0,000 0,01897521 0,07258244 ! mating behavior GO:0007617 7 6 0,000 0,01897521 0,07246723 ! neuron remodeling GO:0016322 15 6 0,000 0,01897521 0,07235239 ! erythrocyte maturation GO:0043249 7 6 0,000 0,01897521 0,07223791 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,01897521 0,07212379 ! equilibrioception GO:0050957 14 6 0,000 0,01897521 0,07201003 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,01897521 0,07189663 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,01897521 0,07178358 ! photoreceptor cell development GO:0042461 10 6 0,000 0,01897521 0,07167089 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,01897521 0,07155855 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,01897521 0,07144657 ! response to interferon-gamma GO:0034341 15 6 0,000 0,01897521 0,07133493 ! toxin metabolic process GO:0009404 11 6 0,000 0,01897521 0,07122365 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,01897521 0,07111271 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,01897521 0,07100211 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,01897521 0,07089186 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,01897521 0,07078195 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,01897521 0,07067238 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,01897521 0,07056315 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,01897521 0,07045426 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,01897521 0,0703457 ! thymic T cell selection GO:0045061 12 6 0,000 0,01897521 0,07023747 ! protein lipoylation GO:0009249 10 6 0,000 0,01897521 0,07012958 ! cysteine metabolic process GO:0006534 10 6 0,000 0,01897521 0,07002202 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,01897521 0,06991479 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,01897521 0,06980789 ! glutamate catabolic process GO:0006538 10 6 0,000 0,01897521 0,06970131 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,01897521 0,06959506 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,01897521 0,06948913 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,01897521 0,06938352 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,01897521 0,06927824 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,01897521 0,06917327 ! hyperosmotic response GO:0006972 9 6 0,000 0,01897521 0,06906862 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,01897521 0,06896429 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,01897521 0,06886027 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,01897521 0,06875656 ! urea metabolic process GO:0019627 7 6 0,000 0,01897521 0,06865317 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,01897521 0,06855009 ! neutrophil activation GO:0042119 8 6 0,000 0,01897521 0,06844731 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,01897521 0,06834485 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,01897521 0,06824269 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,01897521 0,06814083 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,01897521 0,06803928 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,01897521 0,06793803 ! neuron apoptosis GO:0051402 9 6 0,000 0,01897521 0,06783708 ! nucleoside salvage GO:0043174 9 6 0,000 0,01897521 0,06773644 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,01897521 0,06763608 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,01897521 0,06753603 ! T cell mediated immunity GO:0002456 16 6 0,000 0,01897521 0,06743627 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,01897521 0,06733681 GO:0010543|regulation of platelet activation, ! carnitine transport GO:0015879 10 6 0,000 0,01897521 0,06723764 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,01897521 0,06713876 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01897521 0,06704017 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,01897521 0,06694187 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,01897521 0,06684386 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,01897521 0,06674614 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,01897521 0,0666487 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,01897521 0,06655154 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,01897521 0,06645467 ! establishment of spindle localization GO:0051293 12 6 0,000 0,01897521 0,06635808 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,01897521 0,06626177 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,01897521 0,06616574 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,01897521 0,06606998 ! neural nucleus development GO:0048857 14 6 0,000 0,01897521 0,0659745 ! astrocyte development GO:0014002 15 6 0,000 0,01897521 0,0658793 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,01897521 0,06578438 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,01897521 0,06568972 ! interaction with symbiont GO:0051702 13 6 0,000 0,01897521 0,06559534 ! regulation of dendrite development GO:0050773 16 6 0,000 0,01897521 0,06550123 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,01897521 0,06540739 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,01897521 0,06531382 ! response to copper ion GO:0046688 10 6 0,000 0,01897521 0,06522051 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,01897521 0,06512747 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,01897521 0,0650347 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01897521 0,06494219 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,01897521 0,06484994 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,01897521 0,06475795 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,01897521 0,06466623 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,01897521 0,06457476 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,01897521 0,06448356 ! hair follicle maturation GO:0048820 7 6 0,000 0,01897521 0,06439261 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,01897521 0,06430191 ! Schwann cell development GO:0014044 15 6 0,000 0,01897521 0,06421147 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,01897521 0,06412129 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,01897521 0,06403136 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,01897521 0,06394168 ! subpallium development GO:0021544 10 6 0,000 0,01897521 0,06385225 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,01897521 0,06376307 ! histone ubiquitination GO:0016574 8 6 0,000 0,01897521 0,06367414 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,01897521 0,06358546 ! maintenance of organ identity GO:0048496 9 6 0,000 0,01897521 0,06349702 ! G2 phase GO:0051319 16 6 0,000 0,01897521 0,06340883 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,01897521 0,06332088 ! establishment of planar polarity GO:0001736 7 6 0,000 0,01897521 0,06323318 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,01897521 0,06314572 ! membrane to membrane docking GO:0022614 14 6 0,000 0,01897521 0,0630585 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,01897521 0,06297153 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,01897521 0,06288479 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,01897521 0,06279829 ! receptor internalization GO:0031623 10 6 0,000 0,01897521 0,06271203 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,01897521 0,062626 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,01897521 0,06254022 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01897521 0,06245466 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,01897521 0,06236934 ! protein deubiquitination GO:0016579 14 6 0,000 0,01897521 0,06228425 ! protein destabilization GO:0031648 9 6 0,000 0,01897521 0,0621994 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,01897521 0,06211477 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,01897521 0,06203038 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,01897521 0,06194621 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,01897521 0,06186227 ! progesterone metabolic process GO:0042448 10 6 0,000 0,01897521 0,06177856 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,01897521 0,06169508 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,01897521 0,06161182 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,01897521 0,06152878 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,01897521 0,06144597 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,01897521 0,06136338 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,01897521 0,06128102 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,01897521 0,06119887 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,01897521 0,06111694 ! catecholamine transport GO:0051937 9 6 0,000 0,01897521 0,06103524 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,01897521 0,06095375 ! sensory cilium assembly GO:0035058 10 6 0,000 0,01897521 0,06087248 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,01897521 0,06079142 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,01897521 0,06071058 ! maternal placenta development GO:0001893 12 6 0,000 0,01897521 0,06062996 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,01897521 0,06054955 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,01897521 0,06046935 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,01897521 0,06038936 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,01897521 0,06030959 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,01897521 0,06023002 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,01897521 0,06015067 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,01897521 0,06007152 ! activation of MAPK activity GO:0000187 115 67 1,000 0,01943661 0,06145137 ! chromosome segregation GO:0007059 113 67 1,000 0,01943661 0,06137072 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 1,000 0,01943661 0,06129029 ! negative regulation of ligase activity GO:0051352 112 68 1,000 0,01998458 0,06293573 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! viral reproduction GO:0016032 134 68 1,000 0,01998458 0,06285346 ! regulation of lipase activity GO:0060191 130 68 1,000 0,01998458 0,06277141 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 1,000 0,01998458 0,06268957 ! cell cycle checkpoint GO:0000075 137 69 1,000 0,02053899 0,06434479 ! cAMP-mediated signaling GO:0019933 120 69 1,000 0,02053899 0,06426112 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 1,000 0,02053899 0,06417766 ! urogenital system development GO:0001655 137 69 1,000 0,02053899 0,06409442 ! amine catabolic process GO:0009310 117 71 1,000 0,02166693 0,06752673 ! tRNA transcription GO:0009304 14 7 0,000 0,02210292 0,0687964 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,02210292 0,06870752 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,02210292 0,06861886 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,02210292 0,06853044 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,02210292 0,06844224 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,02210292 0,06835427 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,02210292 0,06826652 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,02210292 0,068179 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,02210292 0,0680917 ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,02210292 0,06800463 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,02210292 0,06791778 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,02210292 0,06783115 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,02210292 0,06774474 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,02210292 0,06765855 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 0,02210292 0,06757258 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,02210292 0,06748683 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,02210292 0,06740129 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,02210292 0,06731597 ! glycolipid transport GO:0046836 10 7 0,000 0,02210292 0,06723087 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,02210292 0,06714598 GO:0051923|sulfation, ! neuron adhesion GO:0007158 12 7 0,000 0,02210292 0,06706131 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,02210292 0,06697685 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,02210292 0,0668926 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,02210292 0,06680857 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,02210292 0,06672474 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,02210292 0,06664113 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,02210292 0,06655772 ! mRNA stabilization GO:0048255 18 7 0,000 0,02210292 0,06647452 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,02210292 0,06639154 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,02210292 0,06630875 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,02210292 0,06622618 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,02210292 0,06614381 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,02210292 0,06606164 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,02210292 0,06597968 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,02210292 0,06589792 ! lipoprotein transport GO:0042953 14 7 0,000 0,02210292 0,06581636 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,02210292 0,06573501 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,02210292 0,06565385 ! rhythmic behavior GO:0007622 15 7 0,000 0,02210292 0,0655729 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,02210292 0,06549214 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,02210292 0,06541159 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,02210292 0,06533123 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,02210292 0,06525107 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,02210292 0,0651711 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,02210292 0,06509133 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,02210292 0,06501176 ! mechanosensory behavior GO:0007638 14 7 0,000 0,02210292 0,06493238 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,02210292 0,06485319 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,02210292 0,0647742 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,02210292 0,0646954 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,02210292 0,06461679 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,02210292 0,06453837 ! spinal cord patterning GO:0021511 13 7 0,000 0,02210292 0,06446015 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,02210292 0,06438211 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,02210292 0,06430426 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,02210292 0,06422659 ! adrenal gland development GO:0030325 17 7 0,000 0,02210292 0,06414912 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,02210292 0,06407183 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,02210292 0,06399473 ! ovulation GO:0030728 9 7 0,000 0,02210292 0,06391781 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,02210292 0,06384108 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,02210292 0,06376453 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,02210292 0,06368817 ! microtubule nucleation GO:0007020 20 7 0,000 0,02210292 0,06361199 ! proline biosynthetic process GO:0006561 10 7 0,000 0,02210292 0,06353599 ! thyroid hormone generation GO:0006590 13 7 0,000 0,02210292 0,06346017 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,02210292 0,06338453 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,02210292 0,06330907 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,02210292 0,06323379 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,02210292 0,06315869 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,02210292 0,06308377 ! galactose metabolic process GO:0006012 13 7 0,000 0,02210292 0,06300903 ! vesicle fusion GO:0006906 17 7 0,000 0,02210292 0,06293446 ! response to dietary excess GO:0002021 8 7 0,000 0,02210292 0,06286007 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,02210292 0,06278586 ! intracellular pH reduction GO:0051452 11 7 0,000 0,02210292 0,06271182 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,02210292 0,06263795 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,02210292 0,06256426 ! organ growth GO:0035265 15 7 0,000 0,02210292 0,06249074 ! purine salvage GO:0043101 10 7 0,000 0,02210292 0,06241739 ! nucleoside transport GO:0015858 8 7 0,000 0,02210292 0,06234422 ! parturition GO:0007567 14 7 0,000 0,02210292 0,06227122 ! rRNA modification GO:0000154 14 7 0,000 0,02210292 0,06219839 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,02210292 0,06212572 ! spindle checkpoint GO:0031577 15 7 0,000 0,02210292 0,06205323 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,02210292 0,06198091 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,02210292 0,06190875 ! macrophage differentiation GO:0030225 11 7 0,000 0,02210292 0,06183677 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,02210292 0,06176495 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,02210292 0,06169329 GO:0046676|negative regulation of insulin secretion, ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,02210292 0,06162181 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,02210292 0,06155049 ! fibrinolysis GO:0042730 10 7 0,000 0,02210292 0,06147933 ! eating behavior GO:0042755 7 7 0,000 0,02210292 0,06140834 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,02210292 0,06133751 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,02210292 0,06126684 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,02210292 0,06119634 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,02210292 0,061126 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,02210292 0,06105582 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,02210292 0,0609858 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,02210292 0,06091594 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,02210292 0,06084625 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,02210292 0,06077671 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,02210292 0,06070733 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,02210292 0,06063811 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,02210292 0,06056904 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,02210292 0,06050014 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,02210292 0,06043139 ! regulation of meiosis GO:0040020 12 7 0,000 0,02210292 0,06036279 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,02210292 0,06029435 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,02210292 0,06022607 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,02210292 0,06015794 ! oxygen homeostasis GO:0032364 12 7 0,000 0,02210292 0,06008997 ! transcription termination GO:0006353 13 7 0,000 0,02210292 0,06002214 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,02210292 0,05995448 ! anaphase GO:0051322 17 7 0,000 0,02210292 0,05988696 GO:0000090|mitotic anaphase, ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,02210292 0,05981959 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,02210292 0,05975238 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,02210292 0,05968532 ! diuresis GO:0030146 12 7 0,000 0,02210292 0,05961841 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,02210292 0,05955165 ! thiamin metabolic process GO:0006772 7 7 0,000 0,02210292 0,05948503 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,02210292 0,05941857 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,02210292 0,05935225 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,02210292 0,05928609 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,02210292 0,05922007 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,02210292 0,05915419 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,02210292 0,05908847 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,02210292 0,05902289 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,02210292 0,05895745 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,02210292 0,05889216 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,02210292 0,05882701 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,02210292 0,05876201 ! lymph node development GO:0048535 10 7 0,000 0,02210292 0,05869715 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,02210292 0,05863244 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,02210292 0,05856786 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,02210292 0,05850343 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,02210292 0,05843914 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,02210292 0,05837499 ! adult feeding behavior GO:0008343 9 7 0,000 0,02210292 0,05831099 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,02210292 0,05824712 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,02210292 0,05818339 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,02210292 0,0581198 ! muscle adaptation GO:0043500 14 7 0,000 0,02210292 0,05805635 ! embryonic heart tube development GO:0035050 10 7 0,000 0,02210292 0,05799304 ! retina homeostasis GO:0001895 12 7 0,000 0,02210292 0,05792987 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,02210292 0,05786683 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,02210292 0,05780393 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,02210292 0,05774117 ! protein prenylation GO:0018342 18 7 0,000 0,02210292 0,05767855 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,02210292 0,05761606 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,02210292 0,0575537 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,02210292 0,05749148 ! acute inflammatory response GO:0002526 113 72 1,000 0,02224038 0,05778656 ! regulation of caspase activity GO:0043281 122 72 1,000 0,02224038 0,05772423 ! phosphoinositide metabolic process GO:0030384 128 72 1,000 0,02224038 0,05766202 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 1,000 0,02224038 0,05759995 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 1,000 0,02224038 0,05753802 ! regulation of endopeptidase activity GO:0052548 125 74 1,000 0,02340601 0,06048856 ! regulation of vesicle-mediated transport GO:0060627 119 75 1,000 0,02399809 0,06195216 ! lymphocyte differentiation GO:0030098 167 75 1,000 0,02399809 0,06188576 ! development of primary sexual characteristics GO:0045137 124 76 1,000 0,0245963 0,0633605 ! steroid biosynthetic process GO:0006694 131 76 1,000 0,0245963 0,06329274 ! positive regulation of ligase activity GO:0051351 124 77 1,000 0,02520059 0,06477845 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 0,02520059 0,06470932 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,02522076 0,06469205 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,02522076 0,06462315 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,02522076 0,0645544 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,02522076 0,0644858 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,02522076 0,06441735 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,02522076 0,06434903 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,02522076 0,06428087 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,02522076 0,06421285 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,02522076 0,06414497 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,02522076 0,06407723 ! oligopeptide transport GO:0006857 15 8 0,000 0,02522076 0,06400964 ! UTP metabolic process GO:0046051 8 8 0,000 0,02522076 0,06394219 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,02522076 0,06387488 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,02522076 0,06380772 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,02522076 0,06374069 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,02522076 0,06367381 ! succinate metabolic process GO:0006105 14 8 0,000 0,02522076 0,06360706 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,02522076 0,06354046 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,02522076 0,063474 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,02522076 0,06340767 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,02522076 0,06334148 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,02522076 0,06327543 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,02522076 0,06320952 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,02522076 0,06314375 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,02522076 0,06307811 ! reflex GO:0060004 16 8 0,000 0,02522076 0,06301261 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,02522076 0,06294724 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,02522076 0,06288201 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,02522076 0,06281691 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,02522076 0,06275195 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,02522076 0,06268713 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,02522076 0,06262244 ! pigment granule organization GO:0048753 16 8 0,000 0,02522076 0,06255788 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,02522076 0,06249345 ! astrocyte differentiation GO:0048708 18 8 0,000 0,02522076 0,06242916 ! histidine metabolic process GO:0006547 16 8 0,000 0,02522076 0,06236499 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,02522076 0,06230096 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,02522076 0,06223707 ! glycine catabolic process GO:0006546 13 8 0,000 0,02522076 0,0621733 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,02522076 0,06210966 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,02522076 0,06204615 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,02522076 0,06198278 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,02522076 0,06191953 ! melanin metabolic process GO:0006582 15 8 0,000 0,02522076 0,06185641 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,02522076 0,06179342 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,02522076 0,06173056 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,02522076 0,06166782 ! macrophage activation GO:0042116 12 8 0,000 0,02522076 0,06160522 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,02522076 0,06154274 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,02522076 0,06148038 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,02522076 0,06141816 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,02522076 0,06135606 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,02522076 0,06129408 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,02522076 0,06123223 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,02522076 0,0611705 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,02522076 0,0611089 ! osteoblast development GO:0002076 16 8 0,000 0,02522076 0,06104742 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,02522076 0,06098607 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,02522076 0,06092484 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,02522076 0,06086373 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,02522076 0,06080275 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,02522076 0,06074188 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,02522076 0,06068114 ! response to UV-B GO:0010224 16 8 0,000 0,02522076 0,06062052 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,02522076 0,06056002 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,02522076 0,06049964 ! intermediate filament organization GO:0045109 12 8 0,000 0,02522076 0,06043938 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,02522076 0,06037924 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,02522076 0,06031922 ! cellular extravasation GO:0045123 12 8 0,000 0,02522076 0,06025932 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,02522076 0,06019954 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,02522076 0,06013988 ! response to antibiotic GO:0046677 11 8 0,000 0,02522076 0,06008034 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,02522076 0,06002091 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,02522076 0,0599616 ! DNA topological change GO:0006265 12 8 0,000 0,02522076 0,05990241 ! response to tropane GO:0014073 15 8 0,000 0,02522076 0,05984333 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,02522076 0,05978437 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 0,000 0,02522076 0,05972553 ! melanosome transport GO:0032402 13 8 0,000 0,02522076 0,0596668 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,02522076 0,05960819 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,02522076 0,0595497 ! mast cell activation GO:0045576 14 8 0,000 0,02522076 0,05949131 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,02522076 0,05943305 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,02522076 0,05937489 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,02522076 0,05931685 ! nucleosome disassembly GO:0006337 14 8 0,000 0,02522076 0,05925893 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,02522076 0,05920111 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,02522076 0,05914341 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,02522076 0,05908582 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,02522076 0,05902835 ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,02522076 0,05897098 ! intracellular lipid transport GO:0032365 13 8 0,000 0,02522076 0,05891373 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,02522076 0,05885659 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,02522076 0,05879955 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,02522076 0,05874263 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,02522076 0,05868582 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,02522076 0,05862912 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,02522076 0,05857253 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,02522076 0,05851605 ! hormone catabolic process GO:0042447 17 8 0,000 0,02522076 0,05845967 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,02522076 0,05840341 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,02522076 0,05834725 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,02522076 0,0582912 ! ATP catabolic process GO:0006200 11 8 0,000 0,02522076 0,05823526 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,02522076 0,05817942 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,02522076 0,0581237 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,02522076 0,05806808 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,02522076 0,05801256 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,02522076 0,05795715 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,02522076 0,05790185 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,02522076 0,05784665 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,02522076 0,05779156 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,02522076 0,05773657 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,02522076 0,05768169 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,02522076 0,05762691 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,02522076 0,05757224 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,02522076 0,05751767 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,02522076 0,0574632 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,02522076 0,05740884 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,02522076 0,05735457 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,02522076 0,05730042 ! regulation of peptidase activity GO:0052547 134 79 1,000 0,02642724 0,05998484 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 1,000 0,02642724 0,05992831 ! regulation of adenylate cyclase activity GO:0045761 156 80 1,000 0,0270495 0,06128164 ! cellular lipid catabolic process GO:0044242 134 80 1,000 0,0270495 0,06122399 ! protein import into nucleus GO:0006606 158 80 1,000 0,0270495 0,06116645 ! T cell activation GO:0042110 168 81 1,000 0,02767767 0,06252815 ! response to hypoxia GO:0001666 171 81 1,000 0,02767767 0,06246949 ! nuclear import GO:0051170 161 81 1,000 0,02767767 0,06241095 ! regulation of cAMP biosynthetic process GO:0030817 161 82 1,000 0,0283117 0,06378086 ! cholesterol metabolic process GO:0008203 136 82 1,000 0,0283117 0,0637212 ! response to drug GO:0042493 143 82 1,000 0,0283117 0,06366164 ! response to nutrient GO:0007584 125 82 1,000 0,0283117 0,0636022 ! regulation of cyclase activity GO:0031279 159 82 1,000 0,0283117 0,06354287 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,02832876 0,06352189 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,02832876 0,06346275 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,02832876 0,06340371 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,02832876 0,06334479 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,02832876 0,06328597 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,02832876 0,06322726 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,02832876 0,06316867 ! phosphate transport GO:0006817 19 9 0,000 0,02832876 0,06311018 ! reproductive behavior GO:0019098 19 9 0,000 0,02832876 0,06305179 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,02832876 0,06299352 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,02832876 0,06293536 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,02832876 0,0628773 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,02832876 0,06281935 ! GTP metabolic process GO:0046039 9 9 0,000 0,02832876 0,0627615 ! RNA methylation GO:0001510 15 9 0,000 0,02832876 0,06270376 ! elastic fiber assembly GO:0048251 15 9 0,000 0,02832876 0,06264613 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,02832876 0,0625886 ! artery development GO:0060840 24 9 0,000 0,02832876 0,06253118 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,02832876 0,06247387 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,02832876 0,06241666 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,02832876 0,06235955 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,02832876 0,06230255 ! chemosensory behavior GO:0007635 20 9 0,000 0,02832876 0,06224565 ! microtubule bundle formation GO:0001578 21 9 0,000 0,02832876 0,06218886 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,02832876 0,06213217 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,02832876 0,06207558 ! leukocyte degranulation GO:0043299 16 9 0,000 0,02832876 0,0620191 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,02832876 0,06196272 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,02832876 0,06190644 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,02832876 0,06185026 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,02832876 0,06179419 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,02832876 0,06173822 ! protein targeting to ER GO:0045047 22 9 0,000 0,02832876 0,06168234 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,02832876 0,06162657 ! T cell selection GO:0045058 23 9 0,000 0,02832876 0,0615709 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,02832876 0,06151533 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,02832876 0,06145987 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,02832876 0,0614045 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,02832876 0,06134923 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,02832876 0,06129406 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,02832876 0,06123899 ! mannose metabolic process GO:0006013 13 9 0,000 0,02832876 0,06118401 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,02832876 0,06112914 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,02832876 0,06107436 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,02832876 0,06101969 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,02832876 0,06096511 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,02832876 0,06091063 ! ruffle organization GO:0031529 15 9 0,000 0,02832876 0,06085624 ! retinol metabolic process GO:0042572 18 9 0,000 0,02832876 0,06080195 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,02832876 0,06074776 ! behavioral fear response GO:0001662 22 9 0,000 0,02832876 0,06069367 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,02832876 0,06063967 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,02832876 0,06058577 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,02832876 0,06053196 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 0,02832876 0,06047825 ! oligodendrocyte development GO:0014003 10 9 0,000 0,02832876 0,06042464 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,02832876 0,06037112 ! segment specification GO:0007379 13 9 0,000 0,02832876 0,06031769 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,02832876 0,06026436 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,02832876 0,06021112 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,02832876 0,06015798 ! response to amine stimulus GO:0014075 13 9 0,000 0,02832876 0,06010493 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,02832876 0,06005197 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,02832876 0,05999911 ! erythrocyte development GO:0048821 15 9 0,000 0,02832876 0,05994634 ! gas homeostasis GO:0033483 16 9 0,000 0,02832876 0,05989366 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,02832876 0,05984108 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,02832876 0,05978859 ! renal water homeostasis GO:0003091 14 9 0,000 0,02832876 0,05973619 ! postreplication repair GO:0006301 22 9 0,000 0,02832876 0,05968388 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,02832876 0,05963166 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,02832876 0,05957954 ! icosanoid secretion GO:0032309 15 9 0,000 0,02832876 0,0595275 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,02832876 0,05947556 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,02832876 0,05942371 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,02832876 0,05937194 ! regulation of cell division GO:0051302 15 9 0,000 0,02832876 0,05932027 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,02832876 0,05926869 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,02832876 0,05921719 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,02832876 0,05916579 ! sterol catabolic process GO:0016127 11 9 0,000 0,02832876 0,05911448 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,02832876 0,05906325 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,02832876 0,05901211 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,02832876 0,05896106 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,02832876 0,0589101 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,02832876 0,05885923 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,02832876 0,05880845 ! musculoskeletal movement GO:0050881 14 9 0,000 0,02832876 0,05875775 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,02832876 0,05870714 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,02832876 0,05865662 ! purine base metabolic process GO:0006144 21 9 0,000 0,02832876 0,05860618 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,02832876 0,05855583 ! pigment granule transport GO:0051904 17 9 0,000 0,02832876 0,05850557 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,02832876 0,05845539 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,02832876 0,0584053 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,02832876 0,0583553 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,02832876 0,05830538 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,02832876 0,05825555 ! response to oxygen levels GO:0070482 176 83 1,000 0,02895155 0,05948543 ! regulation of lyase activity GO:0051339 160 83 1,000 0,02895155 0,05943468 ! regulation of cAMP metabolic process GO:0030814 168 84 1,000 0,02959718 0,06070828 ! regulation of ligase activity GO:0051340 142 84 1,000 0,02959718 0,06065657 ! response to unfolded protein GO:0006986 131 85 1,000 0,03024854 0,06193871 ! positive regulation of cell activation GO:0050867 145 85 1,000 0,03024854 0,06188604 GO:0002696|positive regulation of leukocyte activation, ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,03142695 0,06424235 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,03142695 0,06418782 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,03142695 0,06413337 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,03142695 0,06407902 ! cell volume homeostasis GO:0006884 17 10 0,000 0,03142695 0,06402476 ! N-glycan processing GO:0006491 20 10 0,000 0,03142695 0,0639706 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,03142695 0,06391652 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,03142695 0,06386254 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,03142695 0,06380865 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,03142695 0,06375485 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,03142695 0,06370113 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 0,03142695 0,06364751 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,03142695 0,06359398 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,03142695 0,06354054 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,03142695 0,06348719 ! androgen metabolic process GO:0008209 17 10 0,000 0,03142695 0,06343393 ! phospholipid efflux GO:0033700 16 10 0,000 0,03142695 0,06338076 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,03142695 0,06332768 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,03142695 0,06327468 ! lung alveolus development GO:0048286 26 10 0,000 0,03142695 0,06322178 ! pathogenesis GO:0009405 13 10 0,000 0,03142695 0,06316896 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,03142695 0,06311623 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,03142695 0,06306359 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,03142695 0,06301104 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,03142695 0,06295857 ! endoderm development GO:0007492 16 10 0,000 0,03142695 0,06290619 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,03142695 0,0628539 ! arginine catabolic process GO:0006527 13 10 0,000 0,03142695 0,0628017 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,03142695 0,06274958 ! proline metabolic process GO:0006560 13 10 0,000 0,03142695 0,06269755 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,03142695 0,06264561 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,03142695 0,06259375 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,03142695 0,06254197 ! V(D)J recombination GO:0033151 28 10 0,000 0,03142695 0,06249029 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,03142695 0,06243868 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,03142695 0,06238717 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,03142695 0,06233573 ! B cell proliferation GO:0042100 18 10 0,000 0,03142695 0,06228439 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,03142695 0,06223312 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,03142695 0,06218195 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,03142695 0,06213085 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,03142695 0,06207984 ! epithelial cell development GO:0002064 20 10 0,000 0,03142695 0,06202891 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,03142695 0,06197807 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,03142695 0,06192731 ! macroautophagy GO:0016236 17 10 0,000 0,03142695 0,06187663 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,03142695 0,06182604 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,03142695 0,06177553 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,03142695 0,0617251 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,03142695 0,06167475 ! copper ion homeostasis GO:0055070 13 10 0,000 0,03142695 0,06162449 ! regulation of bone resorption GO:0045124 25 10 0,000 0,03142695 0,0615743 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,03142695 0,0615242 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,03142695 0,06147418 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,03142695 0,06142425 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,03142695 0,06137439 ! blastoderm segmentation GO:0007350 18 10 0,000 0,03142695 0,06132461 ! response to dsRNA GO:0043331 20 10 0,000 0,03142695 0,06127492 ! DNA ligation GO:0006266 19 10 0,000 0,03142695 0,0612253 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,03142695 0,06117577 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,03142695 0,06112631 ! melanosome localization GO:0032400 16 10 0,000 0,03142695 0,06107694 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,03142695 0,06102764 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,03142695 0,06097842 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,03142695 0,06092929 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,03142695 0,06088023 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,03142695 0,06083125 ! mRNA cleavage GO:0006379 17 10 0,000 0,03142695 0,06078235 ! protein sumoylation GO:0016925 15 10 0,000 0,03142695 0,06073353 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,03142695 0,06068479 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,03142695 0,06063612 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,03142695 0,06058754 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,03142695 0,06053903 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,03142695 0,0604906 ! salivary gland development GO:0007431 27 10 0,000 0,03142695 0,06044224 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,03142695 0,06039397 ! apical protein localization GO:0045176 15 10 0,000 0,03142695 0,06034577 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,03142695 0,06029764 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,03142695 0,0602496 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,03142695 0,06020163 ! midbrain development GO:0030901 13 10 0,000 0,03142695 0,06015374 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,03142695 0,06010592 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,03142695 0,06005818 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,03142695 0,06001051 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,03142695 0,05996292 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,03142695 0,05991541 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,03142695 0,05986797 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,03142695 0,05982061 ! detection of calcium ion GO:0005513 23 10 0,000 0,03142695 0,05977332 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,03142695 0,0597261 ! blastocyst formation GO:0001825 17 10 0,000 0,03142695 0,05967896 ! cerebellar cortex development GO:0021695 15 10 0,000 0,03142695 0,0596319 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,03142695 0,05958491 ! activation of innate immune response GO:0002218 12 10 0,000 0,03142695 0,05953799 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,03142695 0,05949115 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,03142695 0,05944438 ! response to nicotine GO:0035094 20 10 0,000 0,03142695 0,05939768 ! establishment of cell polarity GO:0030010 16 10 0,000 0,03142695 0,05935106 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,03142695 0,05930451 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,03142695 0,05925803 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 1,000 0,03156829 0,05947793 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 1,000 0,03156829 0,05943139 ! protein localization in nucleus GO:0034504 176 87 1,000 0,03156829 0,05938492 ! ATP biosynthetic process GO:0006754 159 88 1,000 0,0322366 0,06059473 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 1,000 0,03358987 0,06308917 ! regulation of cell cycle process GO:0010564 149 90 1,000 0,03358987 0,06303996 ! sterol metabolic process GO:0016125 152 91 1,000 0,03427475 0,06427518 ! response to protein stimulus GO:0051789 149 91 1,000 0,03427475 0,06422512 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,03451537 0,06462567 ! respiratory burst GO:0045730 17 11 0,000 0,03451537 0,06457541 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,03451537 0,06452524 ! neuron fate specification GO:0048665 17 11 0,000 0,03451537 0,06447514 ! telencephalon cell migration GO:0022029 20 11 0,000 0,03451537 0,06442512 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,03451537 0,06437518 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,03451537 0,06432531 ! thyroid gland development GO:0030878 26 11 0,000 0,03451537 0,06427553 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,03451537 0,06422582 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,03451537 0,06417618 ! response to pain GO:0048265 24 11 0,000 0,03451537 0,06412663 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,03451537 0,06407715 ! T cell proliferation GO:0042098 26 11 0,000 0,03451537 0,06402774 ! blood vessel remodeling GO:0001974 29 11 0,000 0,03451537 0,06397841 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,03451537 0,06392916 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,03451537 0,06387999 ! bone resorption GO:0045453 16 11 0,000 0,03451537 0,06383088 ! ventral spinal cord development GO:0021517 21 11 0,000 0,03451537 0,06378186 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,03451537 0,06373291 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,03451537 0,06368403 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,03451537 0,06363523 ! melanocyte differentiation GO:0030318 21 11 0,000 0,03451537 0,06358651 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,03451537 0,06353786 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,03451537 0,06348928 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,03451537 0,06344078 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,03451537 0,06339235 GO:0043088|regulation of Cdc42 GTPase activity, ! lipid digestion GO:0044241 18 11 0,000 0,03451537 0,063344 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,03451537 0,06329572 ! UV protection GO:0009650 19 11 0,000 0,03451537 0,06324751 ! adult heart development GO:0007512 14 11 0,000 0,03451537 0,06319938 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,03451537 0,06315132 ! temperature homeostasis GO:0001659 17 11 0,000 0,03451537 0,06310333 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,03451537 0,06305541 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,03451537 0,06300757 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,03451537 0,0629598 ! regulation of organ growth GO:0046620 13 11 0,000 0,03451537 0,06291211 ! pigment granule localization GO:0051875 20 11 0,000 0,03451537 0,06286448 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,03451537 0,06281693 ! vasoconstriction GO:0042310 18 11 0,000 0,03451537 0,06276945 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,03451537 0,06272204 ! embryonic axis specification GO:0000578 18 11 0,000 0,03451537 0,0626747 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,03451537 0,06262744 ! snRNA metabolic process GO:0016073 24 11 0,000 0,03451537 0,06258024 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,03451537 0,06253312 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,03451537 0,06248607 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,03451537 0,06243908 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,03451537 0,06239217 ! zymogen activation GO:0031638 15 11 0,000 0,03451537 0,06234533 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,03451537 0,06229856 ! neuroblast proliferation GO:0007405 24 11 0,000 0,03451537 0,06225186 ! nucleosome positioning GO:0016584 15 11 0,000 0,03451537 0,06220523 ! regulation of isotype switching GO:0045191 22 11 0,000 0,03451537 0,06215867 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,03451537 0,06211218 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,03451537 0,06206576 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,03451537 0,0620194 ! acid secretion GO:0046717 18 11 0,000 0,03451537 0,06197312 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,03451537 0,06192691 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,03451537 0,06188076 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,03451537 0,06183468 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,03451537 0,06178868 ! thymus development GO:0048538 27 11 0,000 0,03451537 0,06174274 ! cholesterol efflux GO:0033344 19 11 0,000 0,03451537 0,06169687 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,03451537 0,06165106 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,03451537 0,06160533 ! germ cell migration GO:0008354 25 11 0,000 0,03451537 0,06155966 ! embryonic gut development GO:0048566 15 11 0,000 0,03451537 0,06151406 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,03451537 0,06146853 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,03451537 0,06142306 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,03451537 0,06137767 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,03451537 0,06133233 ! defense response to fungus GO:0050832 13 11 0,000 0,03451537 0,06128707 ! developmental induction GO:0031128 19 11 0,000 0,03451537 0,06124187 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,03451537 0,06119674 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,03451537 0,06115168 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,03451537 0,06110668 ! sequestering of metal ion GO:0051238 14 11 0,000 0,03451537 0,06106175 ! lamellipodium assembly GO:0030032 20 11 0,000 0,03451537 0,06101689 ! nucleus localization GO:0051647 19 11 0,000 0,03451537 0,06097209 ! regulation of synapse organization GO:0050807 17 11 0,000 0,03451537 0,06092735 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 1,000 0,0356608 0,06290313 GO:0010498|proteasomal protein catabolic process, ! regulation of nucleotide metabolic process GO:0006140 182 93 1,000 0,0356608 0,06285705 ! negative regulation of multicellular organismal process GO:0051241 166 93 1,000 0,0356608 0,06281104 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,03759404 0,06616772 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,03759404 0,06611935 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,03759404 0,06607105 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,03759404 0,06602282 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,03759404 0,06597467 ! cartilage condensation GO:0001502 20 12 0,000 0,03759404 0,06592658 ! mating GO:0007618 17 12 0,000 0,03759404 0,06587856 ! protein complex disassembly GO:0043241 27 12 0,000 0,03759404 0,06583062 GO:0043624|cellular protein complex disassembly, ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,03759404 0,06578274 ! hippocampus development GO:0021766 26 12 0,000 0,03759404 0,06573493 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,03759404 0,0656872 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,03759404 0,06563953 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,03759404 0,06559193 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,03759404 0,0655444 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,03759404 0,06549694 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,03759404 0,06544954 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,03759404 0,06540222 ! drug transport GO:0015893 16 12 0,000 0,03759404 0,06535496 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,03759404 0,06530777 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,03759404 0,06526065 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,03759404 0,0652136 ! polyamine metabolic process GO:0006595 17 12 0,000 0,03759404 0,06516662 ! focal adhesion formation GO:0048041 35 12 0,000 0,03759404 0,0651197 ! mitotic spindle organization GO:0007052 21 12 0,000 0,03759404 0,06507285 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,03759404 0,06502607 ! forebrain cell migration GO:0021885 21 12 0,000 0,03759404 0,06497936 ! asymmetric protein localization GO:0008105 20 12 0,000 0,03759404 0,06493271 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,03759404 0,06488613 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,03759404 0,06483962 ! entry into host cell GO:0030260 32 12 0,000 0,03759404 0,06479317 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,03759404 0,06474679 ! monoamine transport GO:0015844 18 12 0,000 0,03759404 0,06470048 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,03759404 0,06465423 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,03759404 0,06460805 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,03759404 0,06456193 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,03759404 0,06451588 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,03759404 0,0644699 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,03759404 0,06442398 ! protein homotetramerization GO:0051289 21 12 0,000 0,03759404 0,06437813 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,03759404 0,06433234 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,03759404 0,06428662 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,03759404 0,06424096 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,03759404 0,06419536 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,03759404 0,06414984 ! cranial nerve development GO:0021545 20 12 0,000 0,03759404 0,06410437 ! fucose catabolic process GO:0019317 22 12 0,000 0,03759404 0,06405897 GO:0042355|L-fucose catabolic process, ! histone methylation GO:0016571 26 12 0,000 0,03759404 0,06401364 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,03759404 0,06396836 ! autonomic nervous system development GO:0048483 24 12 0,000 0,03759404 0,06392316 ! gland morphogenesis GO:0022612 29 12 0,000 0,03759404 0,06387801 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,03759404 0,06383293 ! T cell homeostasis GO:0043029 25 12 0,000 0,03759404 0,06378792 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,03759404 0,06374297 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,03759404 0,06369808 ! spleen development GO:0048536 22 12 0,000 0,03759404 0,06365325 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,03759404 0,06360849 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,03759404 0,06356379 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,03759404 0,06351915 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,03759404 0,06347457 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,03759404 0,06343006 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 0,03759404 0,06338561 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,03759404 0,06334122 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,03759404 0,0632969 ! response to cold GO:0009409 17 12 0,000 0,03759404 0,06325263 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,03759404 0,06320843 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,03759404 0,06316429 ! leukocyte differentiation GO:0002521 202 96 1,000 0,03777997 0,06343238 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 1,000 0,03777997 0,06338814 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 1,000 0,03849689 0,064546 ! protein ubiquitination GO:0016567 217 97 1,000 0,03849689 0,06450105 ! response to virus GO:0009615 160 98 1,000 0,03921901 0,06566523 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 1,000 0,03921901 0,06561957 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 1,000 0,03994629 0,06678998 ! skeletal muscle tissue development GO:0007519 186 99 1,000 0,03994629 0,0667436 GO:0060538|skeletal muscle organ development, ! cGMP metabolic process GO:0046068 18 13 0,000 0,040663 0,06789395 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,040663 0,06784687 ! regulation of chemokine production GO:0032642 18 13 0,000 0,040663 0,06779985 ! peroxisomal transport GO:0043574 24 13 0,000 0,040663 0,06775289 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,040663 0,06770601 ! lipid localization GO:0010876 28 13 0,000 0,040663 0,06765918 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,040663 0,06761243 ! organelle fusion GO:0048284 32 13 0,000 0,040663 0,06756573 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,040663 0,0675191 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,040663 0,06747254 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,040663 0,06742604 ! endocrine pancreas development GO:0031018 22 13 0,000 0,040663 0,0673796 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,040663 0,06733323 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,040663 0,06728692 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,040663 0,06724067 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,040663 0,06719449 ! methionine metabolic process GO:0006555 27 13 0,000 0,040663 0,06714837 ! plasma membrane organization GO:0007009 24 13 0,000 0,040663 0,06710232 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,040663 0,06705633 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,040663 0,0670104 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,040663 0,06696453 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,040663 0,06691873 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,040663 0,06687299 ! cytokine metabolic process GO:0042107 22 13 0,000 0,040663 0,06682731 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,040663 0,06678169 ! exocrine system development GO:0035272 32 13 0,000 0,040663 0,06673614 ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,040663 0,06669065 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,040663 0,06664522 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,040663 0,06659985 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,040663 0,06655454 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,040663 0,0665093 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,040663 0,06646412 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,040663 0,066419 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,040663 0,06637393 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,040663 0,06632894 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,040663 0,066284 ! ribosome assembly GO:0042255 17 13 0,000 0,040663 0,06623912 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,040663 0,0661943 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,040663 0,06614955 ! chromatin silencing GO:0006342 26 13 0,000 0,040663 0,06610485 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,040663 0,06606022 ! regulation of epidermis development GO:0045682 19 13 0,000 0,040663 0,06601564 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,040663 0,06597113 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,040663 0,06592667 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,040663 0,06588228 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,040663 0,06583794 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,040663 0,06579367 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,040663 0,06574945 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,040663 0,06570529 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,040663 0,06566119 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,040663 0,06561716 ! embryonic placenta development GO:0001892 23 13 0,000 0,040663 0,06557318 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,040663 0,06552926 ! insulin secretion GO:0030073 23 13 0,000 0,040663 0,06548539 ! actin filament polymerization GO:0030041 24 13 0,000 0,040663 0,06544159 ! acrosome reaction GO:0007340 18 13 0,000 0,040663 0,06539785 ! rRNA transcription GO:0009303 25 14 0,000 0,04372227 0,07027107 ! lactation GO:0007595 26 14 0,000 0,04372227 0,07022416 ! reproductive cellular process GO:0048610 20 14 0,000 0,04372227 0,07017731 ! tRNA modification GO:0006400 20 14 0,000 0,04372227 0,07013053 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,04372227 0,0700838 ! water transport GO:0006833 21 14 0,000 0,04372227 0,07003714 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,04372227 0,06999055 ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,04372227 0,06994401 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,04372227 0,06989754 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,04372227 0,06985112 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,04372227 0,06980477 ! RNA polyadenylation GO:0043631 30 14 0,000 0,04372227 0,06975848 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,04372227 0,06971225 ! palate development GO:0060021 31 14 0,000 0,04372227 0,06966609 ! regulated secretory pathway GO:0045055 23 14 0,000 0,04372227 0,06961998 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,04372227 0,06957394 ! arginine metabolic process GO:0006525 17 14 0,000 0,04372227 0,06952795 ! regulation of heart rate GO:0002027 24 14 0,000 0,04372227 0,06948203 ! organic alcohol transport GO:0015850 29 14 0,000 0,04372227 0,06943617 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,04372227 0,06939036 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,04372227 0,06934462 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,04372227 0,06929894 ! neutral amino acid transport GO:0015804 26 14 0,000 0,04372227 0,06925332 ! L-amino acid transport GO:0015807 30 14 0,000 0,04372227 0,06920776 ! bone mineralization GO:0030282 17 14 0,000 0,04372227 0,06916226 ! stem cell development GO:0048864 43 14 0,000 0,04372227 0,06911681 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,04372227 0,06907143 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,04372227 0,06902611 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,04372227 0,06898085 ! cerebellum development GO:0021549 21 14 0,000 0,04372227 0,06893564 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,04372227 0,0688905 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,04372227 0,06884541 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,04372227 0,06880039 ! cofactor transport GO:0051181 26 14 0,000 0,04372227 0,06875542 ! NADP metabolic process GO:0006739 24 14 0,000 0,04372227 0,06871051 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,04372227 0,06866566 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,04372227 0,06862087 ! intestinal absorption GO:0050892 25 14 0,000 0,04372227 0,06857613 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,04372227 0,06853146 ! oxygen transport GO:0015671 21 14 0,000 0,04372227 0,06848684 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,04372227 0,06844228 ! male genitalia development GO:0030539 24 14 0,000 0,04372227 0,06839778 ! regulation of RNA stability GO:0043487 32 14 0,000 0,04372227 0,06835334 ! regulation of axon extension GO:0030516 37 14 0,000 0,04372227 0,06830895 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,04372227 0,06826463 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,04677189 0,07297871 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,04677189 0,07293141 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,04677189 0,07288418 ! superoxide anion generation GO:0042554 20 15 0,000 0,04677189 0,072837 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,04677189 0,07278989 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,04677189 0,07274284 ! copper ion transport GO:0006825 20 15 0,000 0,04677189 0,07269585 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,04677189 0,07264892 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,04677189 0,07260205 ! sulfate transport GO:0008272 23 15 0,000 0,04677189 0,07255524 ! response to cAMP GO:0051591 22 15 0,000 0,04677189 0,07250849 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,04677189 0,0724618 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,04677189 0,07241517 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,04677189 0,0723686 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,04677189 0,07232209 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,04677189 0,07227564 ! response to hexose stimulus GO:0009746 22 15 0,000 0,04677189 0,07222925 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,04677189 0,07218292 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,04677189 0,07213665 ! pituitary gland development GO:0021983 29 15 0,000 0,04677189 0,07209044 ! vesicle coating GO:0006901 33 15 0,000 0,04677189 0,07204428 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,04677189 0,07199819 ! regulation of exocytosis GO:0017157 22 15 0,000 0,04677189 0,07195216 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,04677189 0,07190618 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,04677189 0,07186026 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,04677189 0,0718144 ! regulation of vasodilation GO:0042312 26 15 0,000 0,04677189 0,0717686 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,04677189 0,07172286 ! histone deacetylation GO:0016575 20 15 0,000 0,04677189 0,07167718 ! mRNA splice site selection GO:0006376 38 15 0,000 0,04677189 0,07163155 ! tissue regeneration GO:0042246 26 15 0,000 0,04677189 0,07158599 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,04677189 0,07154048 ! water homeostasis GO:0030104 27 15 0,000 0,04677189 0,07149503 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,04677189 0,07144963 ! muscle maintenance GO:0046716 26 15 0,000 0,04677189 0,0714043 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,04677189 0,07135902 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,04677189 0,0713138 ! dopamine metabolic process GO:0042417 35 15 0,000 0,04677189 0,07126863 ! heme biosynthetic process GO:0006783 29 15 0,000 0,04677189 0,07122353 ! cell killing GO:0001906 29 15 0,000 0,04677189 0,07117848 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,04677189 0,07113348 ! detection of bacterium GO:0016045 18 15 0,000 0,04677189 0,07108855 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,04677189 0,07104367 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,04677189 0,07099885 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,04677189 0,07095408 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,04677189 0,07090937 ! peptide hormone processing GO:0016486 23 15 0,000 0,04677189 0,07086472 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,04981189 0,07542316 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,04981189 0,07537572 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,04981189 0,07532835 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,04981189 0,07528103 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,04981189 0,07523377 ! bone remodeling GO:0046849 27 16 0,000 0,04981189 0,07518657 ! filopodium assembly GO:0046847 32 16 0,000 0,04981189 0,07513943 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,04981189 0,07509235 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,04981189 0,07504533 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,04981189 0,07499837 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,04981189 0,07495147 ! startle response GO:0001964 28 16 0,000 0,04981189 0,07490462 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,04981189 0,07485784 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,04981189 0,07481111 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,04981189 0,07476444 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,04981189 0,07471783 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,04981189 0,07467128 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,04981189 0,07462478 ! protein polyubiquitination GO:0000209 34 16 0,000 0,04981189 0,07457834 ! glutamate metabolic process GO:0006536 22 16 0,000 0,04981189 0,07453196 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,04981189 0,07448564 ! response to osmotic stress GO:0006970 25 16 0,000 0,04981189 0,07443938 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,04981189 0,07439317 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,04981189 0,07434702 ! fructose metabolic process GO:0006000 25 16 0,000 0,04981189 0,07430093 ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,04981189 0,07425489 ! intermediate filament-based process GO:0045103 32 16 0,000 0,04981189 0,07420892 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,04981189 0,07416299 ! negative regulation of immune response GO:0050777 35 16 0,000 0,04981189 0,07411713 ! axon cargo transport GO:0008088 43 16 0,000 0,04981189 0,07407132 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,04981189 0,07402557 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,04981189 0,07397988 ! DNA replication initiation GO:0006270 27 16 0,000 0,04981189 0,07393424 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,04981189 0,07388865 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,04981189 0,07384313 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,04981189 0,07379766 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,04981189 0,07375224 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,04981189 0,07370689 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,04981189 0,07366158 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,04981189 0,07361634 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,04981189 0,07357115 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,04981189 0,07352601 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,04981189 0,07348093 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 0,04981189 0,07343591 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! defense response to virus GO:0051607 37 16 0,000 0,04981189 0,07339094 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,05284229 0,07780816 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,05284229 0,07776057 ! metencephalon development GO:0022037 30 17 0,000 0,05284229 0,07771304 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,05284229 0,07766557 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,05284229 0,07761816 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,05284229 0,0775708 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,05284229 0,0775235 ! inositol metabolic process GO:0006020 28 17 0,000 0,05284229 0,07747626 ! gene silencing by RNA GO:0031047 36 17 0,000 0,05284229 0,07742907 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,05284229 0,07738195 ! glial cell development GO:0021782 27 17 0,000 0,05284229 0,07733488 ! limbic system development GO:0021761 36 17 0,000 0,05284229 0,07728787 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,05284229 0,07724091 ! adult walking behavior GO:0007628 33 17 0,000 0,05284229 0,07719401 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,05284229 0,07714717 ! heart looping GO:0001947 30 17 0,000 0,05284229 0,07710039 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,05284229 0,07705366 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,05284229 0,07700699 ! myoblast differentiation GO:0045445 45 17 0,000 0,05284229 0,07696037 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,05284229 0,07691382 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,05284229 0,07686732 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,05284229 0,07682087 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,05284229 0,07677448 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,05284229 0,07672815 ! glycine metabolic process GO:0006544 28 17 0,000 0,05284229 0,07668187 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,05284229 0,07663565 ! NAD metabolic process GO:0019674 29 17 0,000 0,05284229 0,07658948 ! membrane budding GO:0006900 37 17 0,000 0,05284229 0,07654337 ! DNA integration GO:0015074 29 17 0,000 0,05284229 0,07649732 ! regulation of protein binding GO:0043393 33 17 0,000 0,05284229 0,07645132 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,05284229 0,07640537 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,05284229 0,07635948 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,05284229 0,07631365 ! genitalia development GO:0048806 30 17 0,000 0,05284229 0,07626787 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,05284229 0,07622215 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,05284229 0,07617648 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,05284229 0,07613086 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,05284229 0,0760853 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,05284229 0,0760398 ! steroid catabolic process GO:0006706 31 17 0,000 0,05284229 0,07599435 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,05284229 0,07594895 ! gas transport GO:0015669 25 17 0,000 0,05284229 0,07590361 ! organic cation transport GO:0015695 31 17 0,000 0,05284229 0,07585832 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,05284229 0,07581308 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,05284229 0,0757679 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,05284229 0,07572278 ! microspike assembly GO:0030035 36 17 0,000 0,05284229 0,0756777 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,05284229 0,07563268 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,05284229 0,07558772 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,05586312 0,07986136 ! neuron maturation GO:0042551 42 18 0,000 0,05586312 0,07981394 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,05586312 0,07976657 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,05586312 0,07971926 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,05586312 0,079672 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,05586312 0,0796248 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,05586312 0,07957766 ! memory GO:0007613 31 18 0,000 0,05586312 0,07953057 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,05586312 0,07948354 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,05586312 0,07943657 ! patterning of blood vessels GO:0001569 39 18 0,000 0,05586312 0,07938965 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,05586312 0,07934278 GO:0042744|hydrogen peroxide catabolic process, ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,05586312 0,07929597 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,05586312 0,07924922 ! glutamine metabolic process GO:0006541 29 18 0,000 0,05586312 0,07920252 ! response to retinoic acid GO:0032526 26 18 0,000 0,05586312 0,07915587 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,05586312 0,07910928 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,05586312 0,07906275 ! response to fungus GO:0009620 21 18 0,000 0,05586312 0,07901627 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,05586312 0,07896984 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,05586312 0,07892347 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,05586312 0,07887715 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,05586312 0,07883089 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,05586312 0,07878468 ! vitamin transport GO:0051180 27 18 0,000 0,05586312 0,07873853 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,05586312 0,07869243 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,05586312 0,07864638 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,05586312 0,07860039 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,05586312 0,07855445 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,05586312 0,07850857 ! nerve development GO:0021675 28 18 0,000 0,05586312 0,07846274 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,05586312 0,07841696 ! protein secretion GO:0009306 39 19 0,000 0,05887442 0,08259584 ! positive regulation of translation GO:0045727 30 19 0,000 0,05887442 0,0825477 ! negative regulation of defense response GO:0031348 25 19 0,000 0,05887442 0,08249963 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,05887442 0,08245161 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,05887442 0,08240364 ! skin development GO:0043588 36 19 0,000 0,05887442 0,08235573 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,05887442 0,08230788 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,05887442 0,08226008 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,05887442 0,08221234 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,05887442 0,08216465 ! bile acid metabolic process GO:0008206 29 19 0,000 0,05887442 0,08211702 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,05887442 0,08206944 ! cerebral cortex development GO:0021987 36 19 0,000 0,05887442 0,08202192 ! pigmentation during development GO:0048066 41 19 0,000 0,05887442 0,08197446 ! response to vitamin A GO:0033189 27 19 0,000 0,05887442 0,08192704 ! heme metabolic process GO:0042168 36 19 0,000 0,05887442 0,08187969 ! actin filament bundle formation GO:0051017 42 19 0,000 0,05887442 0,08183239 ! neuromuscular junction development GO:0007528 34 19 0,000 0,05887442 0,08178514 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,05887442 0,08173794 ! plasma membrane fusion GO:0045026 28 19 0,000 0,05887442 0,08169081 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,05887442 0,08164372 ! peptide cross-linking GO:0018149 37 19 0,000 0,05887442 0,08159669 ! protein export from nucleus GO:0006611 36 19 0,000 0,05887442 0,08154972 ! heart process GO:0003015 30 19 0,000 0,05887442 0,0815028 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,05887442 0,08145593 ! visual learning GO:0008542 36 19 0,000 0,05887442 0,08140911 ! cellular pigmentation GO:0033059 36 19 0,000 0,05887442 0,08136235 ! G1 phase GO:0051318 40 19 0,000 0,05887442 0,08131565 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,05887442 0,081269 ! cell-cell junction organization GO:0045216 35 19 0,000 0,05887442 0,0812224 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,05887442 0,08117585 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,05887442 0,08112936 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,05887442 0,08108292 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,05887442 0,08103653 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,05887442 0,0809902 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,05887442 0,08094392 ! cilium assembly GO:0042384 37 19 0,000 0,05887442 0,08089769 ! peptide hormone secretion GO:0030072 31 19 0,000 0,05887442 0,08085152 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,06187622 0,08492537 ! positive regulation of ossification GO:0045778 47 20 0,000 0,06187622 0,08487696 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,06187622 0,08482859 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,06187622 0,08478028 ! cAMP metabolic process GO:0046058 36 20 0,000 0,06187622 0,08473203 ! response to vitamin GO:0033273 31 20 0,000 0,06187622 0,08468383 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,06187622 0,08463569 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,06187622 0,0845876 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,06187622 0,08453957 ! response to alkaloid GO:0043279 38 20 0,000 0,06187622 0,08449159 ! retinoid metabolic process GO:0001523 32 20 0,000 0,06187622 0,08444366 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,06187622 0,08439579 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,06187622 0,08434798 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,06187622 0,08430021 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,06187622 0,08425251 GO:0032392|DNA geometric change, ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,06187622 0,08420485 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,06187622 0,08415725 ! body fluid secretion GO:0007589 31 20 0,000 0,06187622 0,08410971 ! peptide secretion GO:0002790 35 20 0,000 0,06187622 0,08406221 ! stem cell differentiation GO:0048863 53 20 0,000 0,06187622 0,08401477 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,06187622 0,08396739 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,06187622 0,08392006 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,06187622 0,08387278 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,06187622 0,08382555 ! diencephalon development GO:0021536 34 20 0,000 0,06187622 0,08377838 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,06187622 0,08373126 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,06187622 0,08368419 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,06187622 0,08363718 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,06187622 0,08359022 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,06187622 0,08354331 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,06187622 0,08349646 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,06187622 0,08344965 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,06187622 0,0834029 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,06187622 0,0833562 ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,06187622 0,08330956 ! actin filament-based movement GO:0030048 43 20 0,000 0,06187622 0,08326296 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,06187622 0,08321642 ! negative regulation of T cell activation GO:0050868 40 20 0,000 0,06187622 0,08316993 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,06187622 0,0831235 ! negative regulation of translation GO:0017148 29 20 0,000 0,06187622 0,08307711 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,06187622 0,08303078 ! regulation of cell killing GO:0031341 42 21 0,000 0,06486854 0,08699761 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,06486854 0,08694914 ! hormone secretion GO:0046879 38 21 0,000 0,06486854 0,08690073 ! glycerol metabolic process GO:0006071 34 21 0,000 0,06486854 0,08685237 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,06486854 0,08680406 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,06486854 0,08675581 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,06486854 0,08670761 ! axis specification GO:0009798 38 21 0,000 0,06486854 0,08665947 ! ovarian follicle development GO:0001541 35 21 0,000 0,06486854 0,08661138 ! smooth muscle contraction GO:0006939 46 21 0,000 0,06486854 0,08656334 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,06486854 0,08651536 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,06486854 0,08646743 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,06486854 0,08641955 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,06486854 0,08637172 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,06486854 0,08632395 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,06486854 0,08627623 ! cytolysis GO:0019835 24 21 0,000 0,06486854 0,08622857 ! vasodilation GO:0042311 39 21 0,000 0,06486854 0,08618095 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,06486854 0,08613339 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,06486854 0,08608588 ! DNA modification GO:0006304 34 21 0,000 0,06486854 0,08603843 ! collagen fibril organization GO:0030199 59 21 0,000 0,06486854 0,08599102 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,06486854 0,08594367 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,06486854 0,08589637 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,06486854 0,08584912 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,06486854 0,08580193 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,06486854 0,08575478 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,06486854 0,08570769 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,06486854 0,08566065 ! collagen catabolic process GO:0030574 28 21 0,000 0,06486854 0,08561366 ! sperm-egg recognition GO:0035036 21 21 0,000 0,06486854 0,08556672 ! gut development GO:0048565 39 21 0,000 0,06486854 0,08551984 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,06785141 0,08940334 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,06785141 0,08935441 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,06785141 0,08930553 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,06785141 0,0892567 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,06785141 0,08920792 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,06785141 0,0891592 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,06785141 0,08911054 ! regeneration GO:0031099 41 22 0,000 0,06785141 0,08906192 ! keratinization GO:0031424 28 22 0,000 0,06785141 0,08901336 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,06785141 0,08896485 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,06785141 0,0889164 ! sensory perception of taste GO:0050909 28 22 0,000 0,06785141 0,08886799 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,06785141 0,08881964 ! vacuolar transport GO:0007034 36 22 0,000 0,06785141 0,08877134 ! lysosome organization GO:0007040 41 22 0,000 0,06785141 0,0887231 ! central nervous system neuron development GO:0021954 46 22 0,000 0,06785141 0,08867491 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,06785141 0,08862677 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,06785141 0,08857868 ! fucose metabolic process GO:0006004 39 22 0,000 0,06785141 0,08853064 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,06785141 0,08848266 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,06785141 0,08843472 ! ureteric bud development GO:0001657 43 22 0,000 0,06785141 0,08838684 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,06785141 0,08833902 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,06785141 0,08829124 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,06785141 0,08824351 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,06785141 0,08819584 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,06785141 0,08814822 ! sarcomere organization GO:0045214 30 22 0,000 0,06785141 0,08810065 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,06785141 0,08805313 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,06785141 0,08800566 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,06785141 0,08795824 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,06785141 0,08791088 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,07082487 0,09171402 ! positive regulation of cell adhesion GO:0045785 56 23 0,000 0,07082487 0,09166468 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,07082487 0,0916154 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,07082487 0,09156617 ! gluconeogenesis GO:0006094 33 23 0,000 0,07082487 0,091517 ! viral genome replication GO:0019079 41 23 0,000 0,07082487 0,09146787 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,07082487 0,0914188 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,07082487 0,09136978 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,07082487 0,09132082 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,07082487 0,0912719 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,07082487 0,09122304 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,07082487 0,09117424 ! visual behavior GO:0007632 42 23 0,000 0,07082487 0,09112548 ! regulation of cell-matrix adhesion GO:0001952 78 23 0,000 0,07082487 0,09107677 GO:0010810|regulation of cell-substrate adhesion, ! response to ethanol GO:0045471 46 23 0,000 0,07082487 0,09102812 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,07082487 0,09097952 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,07082487 0,09093097 ! peroxisome organization GO:0007031 37 23 0,000 0,07082487 0,09088248 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,07082487 0,09083403 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,07082487 0,09078564 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,07082487 0,0907373 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,07082487 0,09068901 GO:0051693|actin filament capping, ! regulation of viral reproduction GO:0050792 38 23 0,000 0,07082487 0,09064077 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,07082487 0,09059258 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,07082487 0,09054445 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,07082487 0,09049636 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,07082487 0,09044833 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,07082487 0,09040034 ! fatty acid transport GO:0015908 44 23 0,000 0,07082487 0,09035241 ! platelet activation GO:0030168 37 23 0,000 0,07082487 0,09030453 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,07082487 0,0902567 ! hormone transport GO:0009914 40 23 0,000 0,07082487 0,09020892 ! cell-cell recognition GO:0009988 25 23 0,000 0,07082487 0,09016119 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,07082487 0,09011351 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,07082487 0,09006588 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,07082487 0,0900183 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,07082487 0,08997077 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,07378895 0,09368665 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,07378895 0,09363724 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,07378895 0,09358788 ! vesicle docking GO:0048278 47 24 0,000 0,07378895 0,09353857 ! spinal cord development GO:0021510 47 24 0,000 0,07378895 0,09348931 ! vacuole organization GO:0007033 43 24 0,000 0,07378895 0,09344011 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,07378895 0,09339095 ! digestive system process GO:0022600 39 24 0,000 0,07378895 0,09334185 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,07378895 0,0932928 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,07378895 0,09324381 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,07378895 0,09319486 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,07378895 0,09314596 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,07378895 0,09309712 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,07378895 0,09304833 ! membrane depolarization GO:0051899 39 24 0,000 0,07378895 0,09299958 ! pallium development GO:0021543 49 24 0,000 0,07378895 0,09295089 ! pentose metabolic process GO:0019321 35 24 0,000 0,07378895 0,09290225 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,07378895 0,09285366 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,07378895 0,09280513 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,07378895 0,09275664 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,07378895 0,0927082 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,07378895 0,09265981 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,07378895 0,09261148 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,07378895 0,09256319 ! regulation of amine transport GO:0051952 40 24 0,000 0,07378895 0,09251496 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,07674366 0,0961694 ! myelination GO:0042552 45 25 0,000 0,07674366 0,09611934 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,07674366 0,09606933 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,07674366 0,09601937 ! phototransduction GO:0007602 33 25 0,000 0,07674366 0,09596947 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,07674366 0,09591961 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 0,000 0,07674366 0,09586981 ! sperm motility GO:0030317 31 25 0,000 0,07674366 0,09582006 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,07674366 0,09577036 ! chromosome condensation GO:0030261 45 25 0,000 0,07674366 0,09572071 ! osteoblast differentiation GO:0001649 60 25 0,000 0,07674366 0,09567111 ! neural crest cell development GO:0014032 54 25 0,000 0,07674366 0,09562157 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,07674366 0,09557208 ! regulation of insulin secretion GO:0050796 37 25 0,000 0,07674366 0,09552263 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,07674366 0,09547324 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,07674366 0,0954239 ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,07674366 0,09537461 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,07674366 0,09532538 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,07674366 0,09527619 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,07674366 0,09522705 ! telomere organization GO:0032200 43 25 0,000 0,07674366 0,09517796 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,07674366 0,09512893 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,07674366 0,09507994 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,07968905 0,09867826 ! embryonic pattern specification GO:0009880 44 26 0,000 0,07968905 0,0986275 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,07968905 0,09857679 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,07968905 0,09852613 ! initiation of viral infection GO:0019059 57 26 0,000 0,07968905 0,09847553 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,07968905 0,09842498 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,07968905 0,09837448 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,07968905 0,09832403 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,07968905 0,09827363 ! molting cycle process GO:0022404 50 26 0,000 0,07968905 0,09822329 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,07968905 0,09817299 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,07968905 0,09812275 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,07968905 0,09807256 ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,07968905 0,09802242 ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,07968905 0,09797233 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,07968905 0,0979223 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,07968905 0,09787231 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,07968905 0,09782237 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,07968905 0,09777249 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,07968905 0,09772266 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,07968905 0,09767288 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,07968905 0,09762314 ! leukocyte proliferation GO:0070661 52 26 0,000 0,07968905 0,09757346 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,07968905 0,09752383 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,07968905 0,09747425 ! neuron fate commitment GO:0048663 48 27 0,000 0,08262514 0,10101427 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,08262514 0,10096297 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,08262514 0,10091172 ! iron ion transport GO:0006826 59 27 0,000 0,08262514 0,10086052 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,08262514 0,10080937 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,08262514 0,10075828 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,08262514 0,10070724 ! fat cell differentiation GO:0045444 50 27 0,000 0,08262514 0,10065625 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,08262514 0,10060531 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,08262514 0,10055442 ! autophagy GO:0006914 41 27 0,000 0,08262514 0,10050358 ! male gonad development GO:0008584 44 27 0,000 0,08262514 0,1004528 ! response to toxin GO:0009636 47 27 0,000 0,08262514 0,10040206 ! primary neural tube formation GO:0014020 51 27 0,000 0,08262514 0,10035138 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,08262514 0,10030075 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,08262514 0,10025017 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,08262514 0,10019964 ! glutathione metabolic process GO:0006749 39 27 0,000 0,08262514 0,10014916 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,08262514 0,10009873 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,08262514 0,10004836 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,08262514 0,09999803 ! negative regulation of lymphocyte activation GO:0051250 53 27 0,000 0,08262514 0,09994775 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,08555196 0,10343619 ! circadian rhythm GO:0007623 50 28 0,000 0,08555196 0,10338423 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,08555196 0,10333233 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,08555196 0,10328049 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,08555196 0,10322869 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,08555196 0,10317695 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,08555196 0,10312526 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,08555196 0,10307362 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,08555196 0,10302203 ! synaptogenesis GO:0007416 42 28 0,000 0,08555196 0,10297049 ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,08555196 0,10291901 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,08555196 0,10286757 ! translational initiation GO:0006413 65 29 0,000 0,08846954 0,10632253 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,08846954 0,10626945 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,08846954 0,10621642 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,08846954 0,10616344 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,08846954 0,10611052 ! catechol metabolic process GO:0009712 54 29 0,000 0,08846954 0,10605765 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,08846954 0,10600483 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,08846954 0,10595207 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,08846954 0,10589936 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,08846954 0,1058467 ! cell fate determination GO:0001709 60 29 0,000 0,08846954 0,10579409 ! detection of light stimulus GO:0009583 38 29 0,000 0,08846954 0,10574153 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,08846954 0,10568903 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,08846954 0,10563658 ! regulation of coagulation GO:0050818 46 29 0,000 0,08846954 0,10558418 ! phenol metabolic process GO:0018958 55 30 0,000 0,0913779 0,10900111 ! zinc ion transport GO:0006829 45 30 0,000 0,0913779 0,10894709 ! membrane docking GO:0022406 61 30 0,000 0,0913779 0,10889313 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,0913779 0,10883922 ! cell junction assembly GO:0034329 78 30 0,000 0,0913779 0,10878537 ! regulation of innate immune response GO:0045088 51 30 0,000 0,0913779 0,10873157 ! myofibril assembly GO:0030239 47 30 0,000 0,0913779 0,10867782 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,0913779 0,10862413 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,0913779 0,10857049 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,0913779 0,1085169 ! phospholipid transport GO:0015914 51 30 0,000 0,0913779 0,10846336 ! ensheathment of neurons GO:0007272 57 30 0,000 0,0913779 0,10840988 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,0913779 0,10835645 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,0913779 0,10830307 ! negative regulation of leukocyte activation GO:0002695 56 30 0,000 0,0913779 0,10824975 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,0913779 0,10819647 ! eye morphogenesis GO:0048592 60 30 0,000 0,0913779 0,10814325 ! response to heat GO:0009408 50 30 0,000 0,0913779 0,10809009 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,09427709 0,1114647 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,09427709 0,11140995 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,09427709 0,11135526 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,09427709 0,11130062 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,09427709 0,11124604 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,09427709 0,1111915 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,09427709 0,11113703 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,09427709 0,1110826 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,09427709 0,11102823 ! ovulation cycle process GO:0022602 49 31 0,000 0,09427709 0,11097391 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,09427709 0,11091964 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,09427709 0,11086543 ! peptide transport GO:0015833 55 31 0,000 0,09427709 0,11081127 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,09427709 0,11075716 ! iron ion homeostasis GO:0055072 54 31 0,000 0,09427709 0,11070311 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,09427709 0,11064911 ! mesoderm formation GO:0001707 69 31 0,000 0,09427709 0,11059516 ! natural killer cell activation GO:0030101 45 31 0,000 0,09427709 0,11054126 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,09427709 0,11048742 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,09427709 0,11043363 ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,09427709 0,11037989 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,09716711 0,11370821 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,09716711 0,11365293 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,09716711 0,11359771 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,09716711 0,11354253 ! cholesterol transport GO:0030301 56 32 0,000 0,09716711 0,11348742 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,09716711 0,11343235 ! spliceosome assembly GO:0000245 67 32 0,000 0,09716711 0,11337734 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,09716711 0,11332238 ! metanephros development GO:0001656 74 32 0,000 0,09716711 0,11326748 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,09716711 0,11321263 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,09716711 0,11315783 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,09716711 0,11310309 ! muscle cell development GO:0055001 49 32 0,000 0,09716711 0,11304839 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,09716711 0,11299375 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,09716711 0,11293917 ! ovulation cycle GO:0042698 51 32 0,000 0,09716711 0,11288463 ! BMP signaling pathway GO:0030509 64 32 0,000 0,09716711 0,11283015 ! hindbrain development GO:0030902 61 32 0,000 0,09716711 0,11277572 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,09716711 0,11272135 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,09716711 0,11266703 ! gene silencing GO:0016458 65 32 0,000 0,09716711 0,11261275 ! protein targeting to membrane GO:0006612 68 33 0,000 0,10004802 0,11589578 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,10004802 0,11584 ! ceramide metabolic process GO:0006672 64 33 0,000 0,10004802 0,11578429 ! formation of primary germ layer GO:0001704 72 33 0,000 0,10004802 0,11572862 ! cell fate specification GO:0001708 52 33 0,000 0,10004802 0,11567301 ! sterol transport GO:0015918 57 33 0,000 0,10004802 0,11561745 ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,10004802 0,11556194 ! adult locomotory behavior GO:0008344 59 33 0,000 0,10004802 0,11550649 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,10004802 0,11545109 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,10291982 0,1187081 ! glial cell differentiation GO:0010001 63 34 0,000 0,10291982 0,11865122 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,10291982 0,11859439 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,10291982 0,11853762 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,10291982 0,11848091 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,10291982 0,11842424 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,10291982 0,11836763 ! spermatid development GO:0007286 63 34 0,000 0,10291982 0,11831108 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,10291982 0,11825458 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,10291982 0,11819813 ! placenta development GO:0001890 53 34 0,000 0,10291982 0,11814174 ! regulation of muscle development GO:0048634 70 35 0,000 0,10578256 0,12136997 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,10578256 0,12131212 ! negative regulation of secretion GO:0051048 63 35 0,000 0,10578256 0,12125433 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,10578256 0,12119659 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,10578256 0,1211389 ! odontogenesis GO:0042476 66 35 0,000 0,10578256 0,12108127 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,10578256 0,1210237 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,10578256 0,12096618 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,10578256 0,12090871 ! cytokine production GO:0001816 59 35 0,000 0,10578256 0,1208513 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,10578256 0,12079394 ! neural tube formation GO:0001841 67 35 0,000 0,10578256 0,12073664 ! vesicle localization GO:0051648 64 35 0,000 0,10578256 0,12067939 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,10863625 0,12387622 ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,10863625 0,12381754 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,10863625 0,12375891 ! cell junction organization GO:0034330 86 36 0,000 0,10863625 0,12370034 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,10863625 0,12364183 ! positive regulation of cell development GO:0010720 80 36 0,000 0,10863625 0,12358337 ! regulation of proteolysis GO:0030162 72 36 0,000 0,10863625 0,12352497 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,10863625 0,12346662 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,10863625 0,12340832 ! aerobic respiration GO:0009060 55 36 0,000 0,10863625 0,12335008 ! androgen receptor signaling pathway GO:0030521 74 36 0,000 0,10863625 0,1232919 ! embryonic organ development GO:0048568 57 36 0,000 0,10863625 0,12323377 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,10863625 0,1231757 ! negative regulation of cell activation GO:0050866 65 36 0,000 0,10863625 0,12311768 ! RNA export from nucleus GO:0006405 56 37 0,000 0,11148094 0,12628208 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,11148094 0,12622265 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,11148094 0,12616328 ! sister chromatid segregation GO:0000819 58 37 0,000 0,11148094 0,12610397 ! actomyosin structure organization GO:0031032 62 37 0,000 0,11148094 0,12604471 ! organic anion transport GO:0015711 68 37 0,000 0,11148094 0,1259855 ! tissue remodeling GO:0048771 76 37 0,000 0,11148094 0,12592635 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,11148094 0,12586726 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,11148094 0,12580823 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,11148094 0,12574924 GO:0015986|ATP synthesis coupled proton transport, ! glycogen metabolic process GO:0005977 61 37 0,000 0,11148094 0,12569032 ! pigment metabolic process GO:0042440 80 37 0,000 0,11148094 0,12563145 ! spermatid differentiation GO:0048515 66 37 0,000 0,11148094 0,12557263 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,11431664 0,12870652 GO:0006956|complement activation, ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,11431664 0,12864632 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,11431664 0,12858617 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,11431664 0,12852609 ! nucleus organization GO:0006997 67 38 0,000 0,11431664 0,12846606 ! lipid homeostasis GO:0055088 67 38 0,000 0,11431664 0,12840608 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,11431664 0,12834616 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,11431664 0,1282863 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,11431664 0,12822649 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,11431664 0,12816674 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,11431664 0,12810705 ! glucan metabolic process GO:0044042 62 38 0,000 0,11431664 0,12804741 GO:0006073|cellular glucan metabolic process, ! learning GO:0007612 77 39 0,000 0,11714338 0,13115262 ! ear morphogenesis GO:0042471 60 39 0,000 0,11714338 0,13109161 ! organic ether metabolic process GO:0018904 55 39 0,000 0,11714338 0,13103067 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,11714338 0,13096978 ! ion transmembrane transport GO:0034220 66 39 0,000 0,11714338 0,13090895 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,11714338 0,13084818 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,11714338 0,13078746 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,11714338 0,1307268 ! RNA modification GO:0009451 57 39 0,000 0,11714338 0,13066619 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,11714338 0,13060564 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,11996119 0,13368533 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,11996119 0,13362344 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,11996119 0,13356161 ! feeding behavior GO:0007631 59 40 0,000 0,11996119 0,13349983 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,11996119 0,13343811 ! mesenchymal cell development GO:0014031 87 40 0,000 0,11996119 0,13337645 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,11996119 0,13331484 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,12277011 0,13637345 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,12277011 0,13631051 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,12277011 0,13624764 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,12277011 0,13618482 ! regulation of T cell proliferation GO:0042129 71 41 0,000 0,12277011 0,13612207 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,12277011 0,13605937 ! regulation of T cell differentiation GO:0045580 70 41 0,000 0,12277011 0,13599672 ! polyol metabolic process GO:0019751 66 41 0,000 0,12277011 0,13593414 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,12277011 0,13587161 ! response to reactive oxygen species GO:0000302 67 42 0,000 0,12557015 0,13890657 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,12557015 0,13884273 ! regulation of tube size GO:0035150 71 42 0,000 0,12557015 0,13877895 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,12557015 0,13871524 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,12557015 0,13865158 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,12557015 0,13858797 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,12557015 0,13852443 ! regulation of protein secretion GO:0050708 71 42 0,000 0,12557015 0,13846095 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,12557015 0,13839752 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,12836135 0,14140907 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,12836135 0,14134435 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,12836135 0,14127969 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,12836135 0,14121509 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,12836135 0,14115055 ! glucose transport GO:0015758 65 43 0,000 0,12836135 0,14108607 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,12836135 0,14102165 ! neural tube development GO:0021915 77 43 0,000 0,12836135 0,14095728 ! striated muscle contraction GO:0006941 77 43 0,000 0,12836135 0,14089298 ! phagocytosis GO:0006909 90 43 0,000 0,12836135 0,14082873 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,12836135 0,14076454 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,13114373 0,14375026 ! hexose transport GO:0008645 67 44 0,000 0,13114373 0,1436848 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,13114373 0,1436194 ! male sex differentiation GO:0046661 76 44 0,000 0,13114373 0,14355406 ! biopolymer methylation GO:0043414 84 44 0,000 0,13114373 0,14348877 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,13114373 0,14342355 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,13114373 0,14335839 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,13391732 0,14632383 ! glycolysis GO:0006096 65 45 0,000 0,13391732 0,14625741 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,13391732 0,14619105 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,13391732 0,14612475 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,13391732 0,14605851 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,13391732 0,14599233 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,13391732 0,14592621 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,13391732 0,14586015 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,13391732 0,14579415 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,13668215 0,14873688 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,13668215 0,14866964 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,13668215 0,14860246 ! pigmentation GO:0043473 100 46 0,000 0,13668215 0,14853534 ! response to calcium ion GO:0051592 81 47 0,000 0,13943824 0,15146204 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,13943824 0,15139369 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,13943824 0,1513254 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,13943824 0,15125718 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,13943824 0,15118901 ! methylation GO:0032259 90 47 0,000 0,13943824 0,15112091 ! protein homooligomerization GO:0051260 76 47 0,000 0,13943824 0,15105287 ! Notch signaling pathway GO:0007219 96 48 0,000 0,14218563 0,15395978 ! cellular component disassembly GO:0022411 86 48 0,000 0,14218563 0,15389052 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,14218563 0,15382133 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,14218563 0,15375219 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,14218563 0,15368312 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,14218563 0,15361411 ! regulation of lymphocyte differentiation GO:0045619 81 48 0,000 0,14218563 0,15354517 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,14492434 0,15643246 ! regulation of action potential GO:0001508 95 49 0,000 0,14492434 0,15636231 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,14492434 0,15629223 ! regulation of ion transport GO:0043269 77 49 0,000 0,14492434 0,1562222 ! peptide metabolic process GO:0006518 76 49 0,000 0,14492434 0,15615224 ! response to temperature stimulus GO:0009266 76 49 0,000 0,14492434 0,15608234 ! endocrine system development GO:0035270 104 49 0,000 0,14492434 0,15601251 ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,14492434 0,15594274 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,14492434 0,15587302 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,14765439 0,15873837 ! neuromuscular process GO:0050905 99 50 0,000 0,14765439 0,15866747 ! inner ear development GO:0048839 79 50 0,000 0,14765439 0,15859664 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,14765439 0,15852587 ! negative regulation of immune system process GO:0002683 95 50 0,000 0,14765439 0,15845516 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,14765439 0,15838451 ! viral infectious cycle GO:0019058 99 51 0,000 0,15037582 0,16123183 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,15037582 0,16116001 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,15037582 0,16108826 ! excretion GO:0007588 83 51 0,000 0,15037582 0,16101657 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,15037582 0,16094494 ! chromatin remodeling GO:0006338 109 51 0,000 0,15037582 0,16087338 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,15037582 0,16080188 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,15037582 0,16073044 ! vesicle organization GO:0016050 107 51 0,000 0,15037582 0,16065907 ! regulation of cell shape GO:0008360 125 51 0,000 0,15037582 0,16058776 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,15037582 0,16051651 ! regulation of angiogenesis GO:0045765 114 52 0,000 0,15308865 0,16333982 ! membrane fusion GO:0006944 110 52 0,000 0,15308865 0,16326742 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,15308865 0,16319508 ! synapse organization GO:0050808 85 52 0,000 0,15308865 0,1631228 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,15579291 0,16593082 ! regulation of translational initiation GO:0006446 82 53 0,000 0,15579291 0,1658574 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,15579291 0,16578405 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,15579291 0,16571076 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,15579291 0,16563753 ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,15848862 0,16842916 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,15848862 0,1683548 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,15848862 0,1682805 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,15848862 0,16820627 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,15848862 0,16813211 ! chloride transport GO:0006821 90 55 0,000 0,16117581 0,17090745 ! glucose catabolic process GO:0006007 82 55 0,000 0,16117581 0,17083216 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,16117581 0,17075694 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,16117581 0,17068178 ! gastrulation GO:0007369 112 55 0,000 0,16117581 0,17060669 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,16117581 0,17053166 ! RNA elongation GO:0006354 79 55 0,000 0,16117581 0,1704567 ! nuclear export GO:0051168 97 55 0,000 0,16117581 0,17038181 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,16117581 0,17030698 ! regulation of actin filament length GO:0030832 105 56 0,000 0,16385451 0,17306144 ! sensory perception of smell GO:0007608 80 56 0,000 0,16385451 0,1729855 ! skeletal muscle fiber development GO:0048741 111 56 0,000 0,16385451 0,17290963 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,16385451 0,17283383 ! proton transport GO:0015992 94 56 0,000 0,16385451 0,17275809 ! positive regulation of organelle organization GO:0010638 100 56 0,000 0,16385451 0,17268242 ! muscle fiber development GO:0048747 112 57 0,000 0,16652475 0,17541968 ! hydrogen transport GO:0006818 97 58 0,000 0,16918655 0,17814566 ! adult behavior GO:0030534 99 58 0,000 0,16918655 0,17806773 ! positive regulation of secretion GO:0051047 95 59 0,000 0,17183993 0,18078132 ! regulation of cellular component size GO:0032535 109 59 0,000 0,17183993 0,1807023 ! skeletal system morphogenesis GO:0048705 105 59 0,000 0,17183993 0,18062336 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,17183993 0,18054449 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,17183993 0,18046568 ! DNA catabolic process GO:0006308 86 59 0,000 0,17183993 0,18038694 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,17183993 0,18030827 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,17448493 0,18300381 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,17448493 0,18292407 ! camera-type eye development GO:0043010 116 60 0,000 0,17448493 0,1828444 ! kidney development GO:0001822 122 60 0,000 0,17448493 0,1827648 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,17712157 0,18544582 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,17712157 0,18536516 ! mesoderm development GO:0007498 119 61 0,000 0,17712157 0,18528456 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,17712157 0,18520404 ! ear development GO:0043583 103 62 0,000 0,17974987 0,18787063 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,17974987 0,18778906 ! regulation of homeostatic process GO:0032844 134 62 0,000 0,17974987 0,18770755 ! regulation of mitosis GO:0007088 105 63 0,000 0,18236987 0,19036091 GO:0051783|regulation of nuclear division, ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,18236987 0,19027836 ! detection of external stimulus GO:0009581 91 63 0,000 0,18236987 0,19019589 ! steroid hormone receptor signaling pathway GO:0030518 129 63 0,000 0,18236987 0,19011348 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,18498159 0,19275257 ! cell redox homeostasis GO:0045454 102 64 0,000 0,18498159 0,19266913 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,18498159 0,19258576 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,18498159 0,19250246 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,18758504 0,19512737 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,18758504 0,19504305 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,18758504 0,1949588 GO:0035113|embryonic appendage morphogenesis, ! myeloid cell differentiation GO:0030099 111 65 0,000 0,18758504 0,19487462 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,19018027 0,19748543 ! extracellular matrix organization GO:0030198 133 66 0,000 0,19018027 0,19740023 ! secondary metabolic process GO:0019748 116 66 0,000 0,19018027 0,19731511 ! cell projection assembly GO:0030031 120 66 0,000 0,19018027 0,19723006 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,1927673 0,19982685 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,1927673 0,19974079 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,1927673 0,19965481 ! hexose catabolic process GO:0019320 104 67 0,000 0,1927673 0,1995689 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,1927673 0,19948306 ! activation of immune response GO:0002253 105 67 0,000 0,1927673 0,1993973 ! amino acid transport GO:0006865 125 68 0,000 0,19534615 0,20197801 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,19534615 0,20189125 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 0,000 0,19534615 0,20180456 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,19534615 0,20171795 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,19791684 0,20428482 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,19791684 0,20419722 ! antigen processing and presentation GO:0019882 104 69 0,000 0,19791684 0,20410969 ! appendage morphogenesis GO:0035107 135 70 0,000 0,20047941 0,20666386 GO:0035108|limb morphogenesis, ! appendage development GO:0048736 136 71 0,000 0,20303387 0,20920749 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,20303387 0,20911793 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,20303387 0,20902845 ! regulation of immune effector process GO:0002697 137 71 0,000 0,20303387 0,20893905 ! carbohydrate transport GO:0008643 110 72 0,000 0,20558026 0,21146905 ! learning or memory GO:0007611 147 73 0,000 0,20811859 0,2139886 ! regulation of blood pressure GO:0008217 125 73 0,000 0,20811859 0,21389719 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,20811859 0,21380586 ! axon guidance GO:0007411 139 73 0,000 0,20811859 0,21371461 ! fertilization GO:0009566 90 73 0,000 0,20811859 0,21362344 ! transition metal ion transport GO:0000041 126 74 0,000 0,2106489 0,21612847 ! neurotransmitter transport GO:0006836 123 74 0,000 0,2106489 0,21603634 ! exocytosis GO:0006887 133 74 0,000 0,2106489 0,21594429 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,2106489 0,21585232 ! eye development GO:0001654 143 74 0,000 0,2106489 0,21576043 ! cell-matrix adhesion GO:0007160 163 75 0,000 0,21317121 0,21825103 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,21317121 0,2181582 ! phosphoinositide-mediated signaling GO:0048015 131 75 0,000 0,21317121 0,21806545 ! rhythmic process GO:0048511 128 75 0,000 0,21317121 0,21797277 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,21568554 0,22045005 ! defense response to bacterium GO:0042742 89 76 0,000 0,21568554 0,22035644 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,21568554 0,22026291 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,21819192 0,22272794 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,21819192 0,22263349 ! blood coagulation GO:0007596 146 78 0,000 0,22069038 0,22508735 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,22069038 0,22499197 ! negative regulation of organelle organization GO:0010639 161 78 0,000 0,22069038 0,22489667 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,22318093 0,22733841 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,22318093 0,2272422 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,22318093 0,22714607 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,22318093 0,22705003 ! response to metal ion GO:0010038 140 80 0,000 0,22566361 0,22947871 ! muscle cell differentiation GO:0042692 159 80 0,000 0,22566361 0,22938176 ! inorganic anion transport GO:0015698 138 80 0,000 0,22566361 0,2292849 ! digestion GO:0007586 112 81 0,000 0,22813843 0,23170159 ! cell-substrate adhesion GO:0031589 171 81 0,000 0,22813843 0,23160382 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,22813843 0,23150614 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,22813843 0,23140854 ! hemostasis GO:0007599 158 84 0,000 0,23551604 0,23879123 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,23551604 0,23869064 ! nucleosome assembly GO:0006334 122 85 0,000 0,2379597 0,2410657 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,2379597 0,24096424 ! amine biosynthetic process GO:0009309 138 86 0,000 0,24039563 0,24332851 ! response to inorganic substance GO:0010035 153 86 0,000 0,24039563 0,24322619 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,24039563 0,24312395 ! chromatin assembly GO:0031497 124 86 0,000 0,24039563 0,2430218 ! tube morphogenesis GO:0035239 176 86 0,000 0,24039563 0,24291973 ! alcohol catabolic process GO:0046164 130 86 0,000 0,24039563 0,24281775 ! amine transport GO:0015837 155 86 0,000 0,24039563 0,24271585 ! cellular respiration GO:0045333 135 88 0,000 0,2452444 0,24750756 ! regulation of neurological system process GO:0031644 148 88 0,000 0,2452444 0,24740378 ! cellular defense response GO:0006968 114 89 0,000 0,24765728 0,2497332 ! regulation of cell morphogenesis GO:0022604 215 89 0,000 0,24765728 0,24962858 ! regulation of cell adhesion GO:0030155 212 89 0,000 0,24765728 0,24952404 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,25006253 0,25184196 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,25246017 0,25415028 ! nucleosome organization GO:0034728 138 92 0,000 0,25485023 0,25644904 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,25485023 0,25634183 ! vitamin metabolic process GO:0006766 139 92 0,000 0,25485023 0,25623471 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,25723272 0,25852211 ! regulation of membrane potential GO:0042391 164 93 0,000 0,25723272 0,25841417 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,25960768 0,26069118 ! female pregnancy GO:0007565 164 94 0,000 0,25960768 0,26058243 ! transcription initiation GO:0006352 153 94 0,000 0,25960768 0,26047376 ! regulation of T cell activation GO:0050863 158 94 0,000 0,25960768 0,26036518 ! forebrain development GO:0030900 188 95 0,000 0,26197512 0,26263006 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,26197512 0,26252067 ! mRNA transport GO:0051028 169 96 0,000 0,26433507 0,26477526 ! positive regulation of immune response GO:0050778 156 96 0,000 0,26433507 0,26466508 ! detection of stimulus GO:0051606 151 96 0,000 0,26433507 0,26455498 ! hormone metabolic process GO:0042445 157 97 0,000 0,26668755 0,26679844 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,2713702 0,2713702