pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6763-VanDeVijver-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/vantveer-oligo_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! insulin-like growth factor receptor signaling pathway GO:0048009 5 5 2,000 5,33E-06 9,823E-03 ! phosphoinositide 3-kinase cascade GO:0014065 6 6 2,000 1,06E-05 9,765E-03 ! negative regulation of protein kinase activity GO:0006469 37 37 4,000 1,162E-05 7,141E-03 ! negative regulation of kinase activity GO:0033673 38 38 4,000 1,33E-05 6,129E-03 ! negative regulation of transferase activity GO:0051348 40 40 4,000 1,722E-05 6,347E-03 ! release of cytochrome c from mitochondria GO:0001836 9 8 2,000 2,932E-05 9,007E-03 ! cell cycle arrest GO:0007050 49 49 4,000 4,715E-05 0,01241281 ! synapse organization GO:0050808 26 26 3,000 5,527E-05 0,01273238 ! apoptotic mitochondrial changes GO:0008637 11 10 2,000 6,21E-05 0,01271664 ! positive regulation of transferase activity GO:0051347 91 88 5,000 7,932E-05 0,0146185 GO:0033674|positive regulation of kinase activity, ! negative regulation of phosphorylation GO:0042326 13 13 2,000 1,454E-04 0,02436289 ! regulation of cyclin-dependent protein kinase activity GO:0000079 35 35 3,000 1,831E-04 0,02812487 ! negative regulation of phosphorus metabolic process GO:0010563 14 14 2,000 1,84E-04 0,02608288 GO:0045936|negative regulation of phosphate metabolic process, ! axon guidance GO:0007411 39 38 3,000 2,534E-04 0,03336316 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 18 18 2,000 4,028E-04 0,04949621 ! mammary gland development GO:0030879 23 21 2,000 6,451E-04 0,07430948 ! negative regulation of hydrolase activity GO:0051346 21 21 2,000 6,451E-04 0,06993833 ! positive regulation of B cell proliferation GO:0030890 5 5 1,000 6,637E-04 0,06795816 ! glycerol metabolic process GO:0006071 5 5 1,000 6,637E-04 0,06438142 ! 2-oxoglutarate metabolic process GO:0006103 5 5 1,000 6,637E-04 0,06116235 ! amyloid precursor protein catabolic process GO:0042987 5 5 1,000 6,637E-04 0,05824985 ! thymic T cell selection GO:0045061 5 5 1,000 6,637E-04 0,05560213 ! cytoskeletal anchoring at plasma membrane GO:0007016 6 5 1,000 6,637E-04 0,05318465 ! vesicle fusion GO:0006906 5 5 1,000 6,637E-04 0,05096862 ! DNA methylation GO:0006306 5 5 1,000 6,637E-04 0,04892988 GO:0006305|DNA alkylation, ! T cell lineage commitment GO:0002360 5 5 1,000 6,637E-04 0,04704796 ! positive regulation of immunoglobulin mediated immune response GO:0002891 5 5 1,000 6,637E-04 0,04530544 GO:0002714|positive regulation of B cell mediated immunity, ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 5 5 1,000 6,637E-04 0,04368739 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 5 5 1,000 6,637E-04 0,04218093 GO:0002820|negative regulation of adaptive immune response, ! negative regulation of neuroblast proliferation GO:0007406 5 5 1,000 6,637E-04 0,0407749 ! regulation of isotype switching GO:0045191 5 5 1,000 6,637E-04 0,03945958 ! sarcomere organization GO:0045214 5 5 1,000 6,637E-04 0,03822647 ! ATP catabolic process GO:0006200 5 5 1,000 6,637E-04 0,03706809 ! B cell receptor signaling pathway GO:0050853 5 5 1,000 6,637E-04 0,03597785 ! establishment of cell polarity GO:0030010 5 5 1,000 6,637E-04 0,03494991 ! positive regulation of MAP kinase activity GO:0043406 50 49 3,000 6,799E-04 0,03480568 ! positive regulation of protein kinase activity GO:0045860 89 86 4,000 6,821E-04 0,0339758 ! positive regulation of growth GO:0045927 23 23 2,000 8,49E-04 0,04117601 ! T cell differentiation GO:0030217 24 24 2,000 9,646E-04 0,04558319 ! protein amino acid dephosphorylation GO:0006470 55 54 3,000 9,841E-04 0,04534249 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 6 6 1,000 9,903E-04 0,04451476 ! regulation of S phase GO:0033261 6 6 1,000 9,903E-04 0,04345489 ! regulation of B cell proliferation GO:0030888 6 6 1,000 9,903E-04 0,04244431 ! regulation of lipid kinase activity GO:0043550 6 6 1,000 9,903E-04 0,04147966 ! succinate metabolic process GO:0006105 7 6 1,000 9,903E-04 0,04055789 ! negative regulation of protein amino acid phosphorylation GO:0001933 6 6 1,000 9,903E-04 0,0396762 ! positive regulation of cell growth GO:0030307 6 6 1,000 9,903E-04 0,03883202 ! ribonucleoside triphosphate catabolic process GO:0009203 6 6 1,000 9,903E-04 0,03802302 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! oligodendrocyte differentiation GO:0048709 6 6 1,000 9,903E-04 0,03724704 ! ER overload response GO:0006983 6 6 1,000 9,903E-04 0,0365021 ! negative regulation of T cell proliferation GO:0042130 6 6 1,000 9,903E-04 0,03578638 GO:0070667|negative regulation of mast cell proliferation, ! G1 DNA damage checkpoint GO:0031571 6 6 1,000 9,903E-04 0,03509818 ! positive regulation of T cell mediated immunity GO:0002711 6 6 1,000 9,903E-04 0,03443595 ! regulation of T cell differentiation in the thymus GO:0033081 6 6 1,000 9,903E-04 0,03379824 ! nitric oxide metabolic process GO:0046209 6 6 1,000 9,903E-04 0,03318373 GO:0006809|nitric oxide biosynthetic process, ! protein sumoylation GO:0016925 6 6 1,000 9,903E-04 0,03259116 ! alditol metabolic process GO:0019400 6 6 1,000 9,903E-04 0,03201939 ! regulation of embryonic development GO:0045995 6 6 1,000 9,903E-04 0,03146733 ! negative regulation of immune effector process GO:0002698 6 6 1,000 9,903E-04 0,03093399 ! regulation of T cell proliferation GO:0042129 25 25 2,000 1,09E-03 0,0334723 ! negative regulation of immune system process GO:0002683 25 25 2,000 1,09E-03 0,03292358 ! extracellular structure organization GO:0043062 56 56 3,000 1,129E-03 0,03355976 ! induction of apoptosis by intracellular signals GO:0008629 26 26 2,000 1,225E-03 0,03582555 ! regulation of T cell differentiation GO:0045580 26 26 2,000 1,225E-03 0,03526577 ! dephosphorylation GO:0016311 60 59 3,000 1,373E-03 0,03894262 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 7 7 1,000 1,379E-03 0,03850843 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 7 7 1,000 1,379E-03 0,03793368 ! oxaloacetate metabolic process GO:0006107 7 7 1,000 1,379E-03 0,03737583 ! keratinocyte proliferation GO:0043616 7 7 1,000 1,379E-03 0,03683415 ! amyloid precursor protein metabolic process GO:0042982 7 7 1,000 1,379E-03 0,03630795 ! regulation of mRNA processing GO:0050684 7 7 1,000 1,379E-03 0,03579657 ! membrane protein ectodomain proteolysis GO:0006509 7 7 1,000 1,379E-03 0,03529939 GO:0033619|membrane protein proteolysis, ! negative regulation of lymphocyte proliferation GO:0050672 7 7 1,000 1,379E-03 0,03481584 GO:0032945|negative regulation of mononuclear cell proliferation, GO:0070664|negative regulation of leukocyte proliferation, ! response to X-ray GO:0010165 7 7 1,000 1,379E-03 0,03434536 ! regulation of intracellular pH GO:0051453 7 7 1,000 1,379E-03 0,03388742 ! myofibril assembly GO:0030239 7 7 1,000 1,379E-03 0,03344153 GO:0055002|striated muscle cell development, ! axon cargo transport GO:0008088 7 7 1,000 1,379E-03 0,03300723 ! purine nucleoside triphosphate catabolic process GO:0009146 7 7 1,000 1,379E-03 0,03258406 ! purine ribonucleotide catabolic process GO:0009154 7 7 1,000 1,379E-03 0,0321716 ! response to gamma radiation GO:0010332 8 7 1,000 1,379E-03 0,03176945 ! neuromuscular synaptic transmission GO:0007274 7 7 1,000 1,379E-03 0,03137724 ! synaptic transmission, cholinergic GO:0007271 7 7 1,000 1,379E-03 0,03099459 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 7 7 1,000 1,379E-03 0,03062116 ! T cell receptor signaling pathway GO:0050852 7 7 1,000 1,379E-03 0,03025662 ! negative regulation of T cell activation GO:0050868 7 7 1,000 1,379E-03 0,02990066 ! regulation of mast cell proliferation GO:0070666 28 28 2,000 1,525E-03 0,03268209 ! axonogenesis GO:0007409 66 62 3,000 1,653E-03 0,03501149 ! regulation of lymphocyte proliferation GO:0050670 29 29 2,000 1,691E-03 0,03541632 GO:0032944|regulation of mononuclear cell proliferation, GO:0070663|regulation of leukocyte proliferation, ! positive regulation of cell killing GO:0031343 8 8 1,000 1,829E-03 0,03787334 ! organelle fusion GO:0048284 8 8 1,000 1,829E-03 0,03745253 ! T cell selection GO:0045058 8 8 1,000 1,829E-03 0,03704096 ! negative regulation of proteolysis GO:0045861 8 8 1,000 1,829E-03 0,03663834 ! ribonucleotide catabolic process GO:0009261 8 8 1,000 1,829E-03 0,03624438 ! phosphagen metabolic process GO:0006599 8 8 1,000 1,829E-03 0,0358588 GO:0006600|creatine metabolic process, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 8 8 1,000 1,829E-03 0,03548134 ! regulation of T cell mediated immunity GO:0002709 8 8 1,000 1,829E-03 0,03511174 ! muscle cell development GO:0055001 8 8 1,000 1,829E-03 0,03474977 ! nucleoside triphosphate catabolic process GO:0009143 8 8 1,000 1,829E-03 0,03439518 ! regulation of immunoglobulin production GO:0002637 8 8 1,000 1,829E-03 0,03404775 ! branched chain family amino acid metabolic process GO:0009081 8 8 1,000 1,829E-03 0,03370727 ! actin filament polymerization GO:0030041 9 8 1,000 1,829E-03 0,03337354 ! positive regulation of protein metabolic process GO:0051247 64 64 3,000 1,86E-03 0,03359867 ! regulation of MAP kinase activity GO:0043405 67 66 3,000 2,084E-03 0,03728187 ! cell morphogenesis involved in neuron differentiation GO:0048667 72 67 3,000 2,202E-03 0,03902788 GO:0048812|neuron projection morphogenesis, GO:0048858|cell projection morphogenesis, ! negative regulation of cell growth GO:0030308 32 32 2,000 2,255E-03 0,03958899 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 32 32 2,000 2,255E-03 0,03921551 ! regulation of lymphocyte differentiation GO:0045619 32 32 2,000 2,255E-03 0,03884901 ! regulation of cell size GO:0008361 68 68 3,000 2,326E-03 0,03968744 ! positive regulation of cell size GO:0045793 9 9 1,000 2,339E-03 0,03954832 ! regulation of membrane protein ectodomain proteolysis GO:0051043 9 9 1,000 2,339E-03 0,03918879 ! negative regulation of caspase activity GO:0043154 9 9 1,000 2,339E-03 0,03883574 ! T cell differentiation in the thymus GO:0033077 9 9 1,000 2,339E-03 0,03848899 ! regulation of cellular pH GO:0030641 9 9 1,000 2,339E-03 0,03814838 ! regulation of immunoglobulin mediated immune response GO:0002889 9 9 1,000 2,339E-03 0,03781375 GO:0002712|regulation of B cell mediated immunity, ! regulation of leukocyte mediated cytotoxicity GO:0001910 9 9 1,000 2,339E-03 0,03748493 ! defense response to virus GO:0051607 9 9 1,000 2,339E-03 0,03716178 ! activation of protein kinase activity GO:0032147 35 33 2,000 2,467E-03 0,03885321 ! negative regulation of cell size GO:0045792 33 33 2,000 2,467E-03 0,03852395 ! regulation of actin polymerization or depolymerization GO:0008064 33 33 2,000 2,467E-03 0,03820022 ! cell part morphogenesis GO:0032990 75 70 3,000 2,587E-03 0,03972519 ! regulation of actin filament length GO:0030832 34 34 2,000 2,689E-03 0,04096394 ! regulation of protein catabolic process GO:0042176 35 34 2,000 2,689E-03 0,04062817 ! regulation of cell killing GO:0031341 10 10 1,000 2,908E-03 0,04357599 ! negative regulation of nucleocytoplasmic transport GO:0046823 10 10 1,000 2,908E-03 0,04322457 ! phototransduction GO:0007602 11 10 1,000 2,908E-03 0,04287877 ! centrosome cycle GO:0007098 10 10 1,000 2,908E-03 0,04253846 ! purine ribonucleoside metabolic process GO:0046128 10 10 1,000 2,908E-03 0,04220351 GO:0042278|purine nucleoside metabolic process, ! neuromuscular junction development GO:0007528 10 10 1,000 2,908E-03 0,0418738 ! negative regulation of immune response GO:0050777 10 10 1,000 2,908E-03 0,0415492 ! regulation of B cell differentiation GO:0045577 10 10 1,000 2,908E-03 0,04122959 ! positive regulation of neuron apoptosis GO:0043525 10 10 1,000 2,908E-03 0,04091486 ! antigen receptor-mediated signaling pathway GO:0050851 10 10 1,000 2,908E-03 0,0406049 ! regulation of cellular component size GO:0032535 35 35 2,000 2,924E-03 0,04052392 ! response to drug GO:0042493 37 37 2,000 3,431E-03 0,04719411 ! negative regulation of growth GO:0045926 37 37 2,000 3,431E-03 0,04684452 ! DNA damage response, signal transduction GO:0042770 37 37 2,000 3,431E-03 0,04650008 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 11 11 1,000 3,536E-03 0,0475632 ! skin development GO:0043588 11 11 1,000 3,536E-03 0,04721854 ! cellular component assembly involved in morphogenesis GO:0010927 11 11 1,000 3,536E-03 0,04687883 ! microtubule-based transport GO:0010970 11 11 1,000 3,536E-03 0,04654399 ! detection of light stimulus involved in sensory perception GO:0050962 12 11 1,000 3,536E-03 0,04621389 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! T cell proliferation GO:0042098 11 11 1,000 3,536E-03 0,04588844 ! activation of MAPKK activity GO:0000186 12 11 1,000 3,536E-03 0,04556754 ! cellular response to starvation GO:0009267 11 11 1,000 3,536E-03 0,0452511 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 11 11 1,000 3,536E-03 0,04493902 ! G1/S transition checkpoint GO:0031575 12 11 1,000 3,536E-03 0,04463122 ! positive regulation of alpha-beta T cell activation GO:0046635 11 11 1,000 3,536E-03 0,04432761 ! intermediate filament-based process GO:0045103 11 11 1,000 3,536E-03 0,04402809 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 11 11 1,000 3,536E-03 0,0437326 ! negative regulation of lymphocyte activation GO:0051250 11 11 1,000 3,536E-03 0,04344105 ! cell morphogenesis involved in differentiation GO:0000904 82 77 3,000 3,658E-03 0,04464093 ! positive regulation of protein kinase cascade GO:0010740 79 78 3,000 3,832E-03 0,04645941 ! activation of MAPK activity GO:0000187 39 39 2,000 3,989E-03 0,04805074 ! lymphocyte differentiation GO:0030098 39 39 2,000 3,989E-03 0,04773872 ! neuron projection development GO:0031175 85 80 3,000 4,197E-03 0,04990197 ! positive regulation of protein catabolic process GO:0045732 12 12 1,000 4,22E-03 0,04985844 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 12 12 1,000 4,22E-03 0,04954087 ! heterophilic cell adhesion GO:0007157 12 12 1,000 4,22E-03 0,04922732 ! xenobiotic metabolic process GO:0006805 12 12 1,000 4,22E-03 0,04891771 ! negative regulation of peptidase activity GO:0010466 12 12 1,000 4,22E-03 0,04861198 ! actomyosin structure organization GO:0031032 12 12 1,000 4,22E-03 0,04831004 ! microtubule organizing center organization GO:0031023 12 12 1,000 4,22E-03 0,04801183 GO:0051297|centrosome organization, ! glycoprotein catabolic process GO:0006516 13 12 1,000 4,22E-03 0,04771728 ! regulation of alpha-beta T cell activation GO:0046634 12 12 1,000 4,22E-03 0,04742632 ! positive regulation of multicellular organism growth GO:0040018 12 12 1,000 4,22E-03 0,04713889 ! positive regulation of adaptive immune response GO:0002821 12 12 1,000 4,22E-03 0,04685492 ! detection of light stimulus GO:0009583 13 12 1,000 4,22E-03 0,04657435 ! synaptogenesis GO:0007416 12 12 1,000 4,22E-03 0,04629712 ! cellular monovalent inorganic cation homeostasis GO:0030004 12 12 1,000 4,22E-03 0,04602317 ! MAPKKK cascade GO:0000165 82 81 3,000 4,388E-03 0,04757079 ! regulation of caspase activity GO:0043281 41 41 2,000 4,599E-03 0,04956536 ! regulation of endopeptidase activity GO:0052548 42 42 2,000 4,924E-03 0,05275869 ! negative regulation of ligase activity GO:0051352 43 42 2,000 4,924E-03 0,05245373 GO:0051444|negative regulation of ubiquitin-protein ligase activity, GO:0051436|negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 42 42 2,000 4,924E-03 0,05215227 ! G2/M transition of mitotic cell cycle GO:0000086 13 13 1,000 4,961E-03 0,05224776 ! intra-Golgi vesicle-mediated transport GO:0006891 13 13 1,000 4,961E-03 0,05195089 ! positive regulation of JAK-STAT cascade GO:0046427 13 13 1,000 4,961E-03 0,05165739 ! negative regulation of protein modification process GO:0031400 13 13 1,000 4,961E-03 0,05136718 ! regulation of DNA recombination GO:0000018 13 13 1,000 4,961E-03 0,05108021 ! mitochondrial membrane organization GO:0007006 13 13 1,000 4,961E-03 0,05079643 ! negative regulation of DNA replication GO:0008156 13 13 1,000 4,961E-03 0,05051579 ! negative regulation of protein catabolic process GO:0042177 13 13 1,000 4,961E-03 0,05023823 ! cell aging GO:0007569 13 13 1,000 4,961E-03 0,0499637 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 13 13 1,000 4,961E-03 0,04969216 ! response to endoplasmic reticulum stress GO:0034976 13 13 1,000 4,961E-03 0,04942355 ! positive regulation of leukocyte mediated immunity GO:0002705 13 13 1,000 4,961E-03 0,04915783 GO:0002708|positive regulation of lymphocyte mediated immunity, ! neural crest cell migration GO:0001755 14 13 1,000 4,961E-03 0,04889496 ! immunoglobulin production GO:0002377 13 13 1,000 4,961E-03 0,04863488 GO:0002440|production of molecular mediator of immune response, ! negative regulation of intracellular transport GO:0032387 13 13 1,000 4,961E-03 0,04837755 ! negative regulation of leukocyte activation GO:0002695 13 13 1,000 4,961E-03 0,04812293 ! purine nucleotide catabolic process GO:0006195 13 13 1,000 4,961E-03 0,04787098 ! tissue homeostasis GO:0001894 13 13 1,000 4,961E-03 0,04762165 GO:0048871|multicellular organismal homeostasis, ! protein tetramerization GO:0051262 13 13 1,000 4,961E-03 0,04737491 ! mitochondrion organization GO:0007005 44 43 2,000 5,262E-03 0,04999118 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 45 44 2,000 5,614E-03 0,0530633 ! calcium-dependent cell-cell adhesion GO:0016339 14 14 1,000 5,757E-03 0,05413641 ! immune response-activating cell surface receptor signaling pathway GO:0002429 14 14 1,000 5,757E-03 0,05386161 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! actin polymerization or depolymerization GO:0008154 15 14 1,000 5,757E-03 0,05358958 ! base-excision repair GO:0006284 14 14 1,000 5,757E-03 0,05332029 ! DNA modification GO:0006304 14 14 1,000 5,757E-03 0,05305369 ! positive regulation of epithelial cell proliferation GO:0050679 14 14 1,000 5,757E-03 0,05278974 ! primary neural tube formation GO:0014020 15 14 1,000 5,757E-03 0,0525284 ! group transfer coenzyme metabolic process GO:0006752 14 14 1,000 5,757E-03 0,05226964 ! regulation of actin cytoskeleton organization GO:0032956 46 45 2,000 5,98E-03 0,05402909 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 46 45 2,000 5,98E-03 0,05376553 ! regulation of actin filament-based process GO:0032970 47 46 2,000 6,36E-03 0,05690449 ! regulation of peptidase activity GO:0052547 46 46 2,000 6,36E-03 0,05662958 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 47 46 2,000 6,36E-03 0,05635733 ! positive regulation of ligase activity GO:0051351 47 46 2,000 6,36E-03 0,05608768 ! cellular response to hormone stimulus GO:0032870 48 46 2,000 6,36E-03 0,05582059 ! protein import into nucleus, translocation GO:0000060 15 15 1,000 6,608E-03 0,05771722 ! striated muscle cell differentiation GO:0051146 16 15 1,000 6,608E-03 0,05744497 ! detection of stimulus involved in sensory perception GO:0050906 16 15 1,000 6,608E-03 0,05717528 ! insulin receptor signaling pathway GO:0008286 17 15 1,000 6,608E-03 0,0569081 ! ER-nuclear signaling pathway GO:0006984 15 15 1,000 6,608E-03 0,05664341 ! response to starvation GO:0042594 15 15 1,000 6,608E-03 0,05638118 ! response to ionizing radiation GO:0010212 16 15 1,000 6,608E-03 0,05612135 ! regulation of production of molecular mediator of immune response GO:0002700 15 15 1,000 6,608E-03 0,05586392 ! positive regulation of B cell activation GO:0050871 15 15 1,000 6,608E-03 0,05560883 ! negative regulation of cell activation GO:0050866 15 15 1,000 6,608E-03 0,05535606 ! positive regulation of immune effector process GO:0002699 15 15 1,000 6,608E-03 0,05510558 ! regulation of catabolic process GO:0009894 48 47 2,000 6,755E-03 0,05607551 ! actin filament organization GO:0007015 50 48 2,000 7,163E-03 0,05919953 ! regulation of ubiquitin-protein ligase activity GO:0051438 49 48 2,000 7,163E-03 0,05893524 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 16 16 1,000 7,512E-03 0,06153087 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 16 16 1,000 7,512E-03 0,06125861 ! cellular response to reactive oxygen species GO:0034614 16 16 1,000 7,512E-03 0,06098875 ! positive regulation of cytoskeleton organization GO:0051495 16 16 1,000 7,512E-03 0,06072125 ! lymphocyte proliferation GO:0046651 16 16 1,000 7,512E-03 0,0604561 ! positive regulation of MAPKKK cascade GO:0043410 17 16 1,000 7,512E-03 0,06019324 ! cellular response to nutrient levels GO:0031669 16 16 1,000 7,512E-03 0,05993267 ! polyol metabolic process GO:0019751 16 16 1,000 7,512E-03 0,05967434 ! embryonic epithelial tube formation GO:0001838 17 16 1,000 7,512E-03 0,05941822 GO:0001841|neural tube formation, ! positive regulation of catabolic process GO:0009896 16 16 1,000 7,512E-03 0,0591643 ! response to xenobiotic stimulus GO:0009410 16 16 1,000 7,512E-03 0,05891254 ! leukocyte differentiation GO:0002521 50 49 2,000 7,586E-03 0,05924044 ! gland development GO:0048732 51 49 2,000 7,586E-03 0,05899048 ! regulation of ligase activity GO:0051340 50 49 2,000 7,586E-03 0,05874262 ! regulation of cell growth GO:0001558 97 96 3,000 7,995E-03 0,06165131 ! regulation of DNA metabolic process GO:0051052 51 50 2,000 8,023E-03 0,06161138 ! T cell activation GO:0042110 51 50 2,000 8,023E-03 0,06135573 ! regulation of fibroblast proliferation GO:0048145 17 17 1,000 8,468E-03 0,06449335 ! regulation of actin filament depolymerization GO:0030834 17 17 1,000 8,468E-03 0,06422795 ! positive regulation of cell adhesion GO:0045785 17 17 1,000 8,468E-03 0,06396472 ! myelination GO:0042552 17 17 1,000 8,468E-03 0,06370364 ! leukocyte adhesion GO:0007159 17 17 1,000 8,468E-03 0,06344468 ! dicarboxylic acid metabolic process GO:0043648 18 17 1,000 8,468E-03 0,06318782 ! neural crest cell development GO:0014032 19 17 1,000 8,468E-03 0,06293303 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 18 17 1,000 8,468E-03 0,06268029 ! negative regulation of cell development GO:0010721 18 17 1,000 8,468E-03 0,06242957 GO:0050768|negative regulation of neurogenesis, ! immune response-activating signal transduction GO:0002757 17 17 1,000 8,468E-03 0,06218084 GO:0002764|immune response-regulating signal transduction, ! protein modification by small protein conjugation GO:0032446 52 51 2,000 8,475E-03 0,06198279 ! interphase of mitotic cell cycle GO:0051329 52 51 2,000 8,475E-03 0,06173779 GO:0051325|interphase, ! response to light stimulus GO:0009416 53 52 2,000 8,942E-03 0,06488085 ! hemopoiesis GO:0030097 104 100 3,000 9,21E-03 0,06656468 ! regulation of T cell activation GO:0050863 53 53 2,000 9,423E-03 0,06784038 ! mononuclear cell proliferation GO:0032943 18 18 1,000 9,477E-03 0,06795918 GO:0070661|leukocyte proliferation, ! response to calcium ion GO:0051592 18 18 1,000 9,477E-03 0,06769578 ! striated muscle contraction GO:0006941 18 18 1,000 9,477E-03 0,0674344 ! B cell differentiation GO:0030183 18 18 1,000 9,477E-03 0,06717504 ! cellular response to extracellular stimulus GO:0031668 18 18 1,000 9,477E-03 0,06691766 ! ensheathment of neurons GO:0007272 18 18 1,000 9,477E-03 0,06666225 GO:0008366|axon ensheathment, ! negative regulation of catabolic process GO:0009895 18 18 1,000 9,477E-03 0,06640878 ! regulation of cell adhesion GO:0030155 56 55 2,000 0,01043116 0,07282056 ! protein modification by small protein conjugation or removal GO:0070647 56 55 2,000 0,01043116 0,07254576 ! DNA damage checkpoint GO:0000077 19 19 1,000 0,01053563 0,07299684 ! negative regulation of DNA metabolic process GO:0051053 19 19 1,000 0,01053563 0,07272345 ! glial cell differentiation GO:0010001 19 19 1,000 0,01053563 0,07245209 ! regulation of pH GO:0006885 19 19 1,000 0,01053563 0,07218275 ! regulation of JAK-STAT cascade GO:0046425 19 19 1,000 0,01053563 0,07191541 ! positive regulation of T cell proliferation GO:0042102 19 19 1,000 0,01053563 0,07165004 ! multicellular organismal metabolic process GO:0044236 19 19 1,000 0,01053563 0,07138662 ! peptidyl-tyrosine phosphorylation GO:0018108 20 19 1,000 0,01053563 0,07112513 ! ribonucleoside metabolic process GO:0009119 19 19 1,000 0,01053563 0,07086555 ! cellular response to oxidative stress GO:0034599 19 19 1,000 0,01053563 0,07060786 ! regulation of lymphocyte mediated immunity GO:0002706 19 19 1,000 0,01053563 0,07035203 ! positive regulation of T cell differentiation GO:0045582 19 19 1,000 0,01053563 0,07009805 ! peripheral nervous system development GO:0007422 19 19 1,000 0,01053563 0,0698459 ! response to heat GO:0009408 19 19 1,000 0,01053563 0,06959556 ! ATP metabolic process GO:0046034 57 57 2,000 0,01149942 0,07569081 ! establishment or maintenance of cell polarity GO:0007163 21 20 1,000 0,01164445 0,07637268 ! cytoskeleton-dependent intracellular transport GO:0030705 20 20 1,000 0,01164445 0,07610185 ! neural tube development GO:0021915 21 20 1,000 0,01164445 0,07583294 ! positive regulation of gene-specific transcription GO:0043193 20 20 1,000 0,01164445 0,07556592 ! detection of abiotic stimulus GO:0009582 21 20 1,000 0,01164445 0,07530078 ! peptidyl-tyrosine modification GO:0018212 21 20 1,000 0,01164445 0,07503749 ! regulation of B cell activation GO:0050864 20 20 1,000 0,01164445 0,07477603 ! G1/S transition of mitotic cell cycle GO:0000082 21 21 1,000 0,01280227 0,08192567 ! Notch signaling pathway GO:0007219 22 21 1,000 0,01280227 0,08164219 ! morphogenesis of embryonic epithelium GO:0016331 22 21 1,000 0,01280227 0,08136066 ! DNA integrity checkpoint GO:0031570 21 21 1,000 0,01280227 0,08108107 ! regulation of leukocyte mediated immunity GO:0002703 21 21 1,000 0,01280227 0,0808034 ! regulation of action potential in neuron GO:0019228 21 21 1,000 0,01280227 0,08052762 ! regulation of multicellular organism growth GO:0040014 21 21 1,000 0,01280227 0,08025372 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 21 21 1,000 0,01280227 0,07998167 ! regulation of proteolysis GO:0030162 21 21 1,000 0,01280227 0,07971146 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 21 21 1,000 0,01280227 0,07944307 ! cellular response to insulin stimulus GO:0032869 23 21 1,000 0,01280227 0,07917648 ! negative regulation of protein transport GO:0051224 21 21 1,000 0,01280227 0,07891168 ! negative regulation of cellular protein metabolic process GO:0032269 60 60 2,000 0,01321638 0,08119265 ! proteasomal protein catabolic process GO:0010498 62 61 2,000 0,01381953 0,0846159 GO:0043161|proteasomal ubiquitin-dependent protein catabolic process, ! regulation of protein amino acid phosphorylation GO:0001932 62 61 2,000 0,01381953 0,08433572 ! positive regulation of cellular protein metabolic process GO:0032270 61 61 2,000 0,01381953 0,08405738 ! positive regulation of DNA metabolic process GO:0051054 23 22 1,000 0,01400824 0,08492497 ! cellular amide metabolic process GO:0043603 22 22 1,000 0,01400824 0,08464652 ! positive regulation of lymphocyte proliferation GO:0050671 22 22 1,000 0,01400824 0,0843699 GO:0032946|positive regulation of mononuclear cell proliferation, GO:0070665|positive regulation of leukocyte proliferation, GO:0070668|positive regulation of mast cell proliferation, ! maintenance of protein location in cell GO:0032507 23 22 1,000 0,01400824 0,08409508 ! biopolymer methylation GO:0043414 22 22 1,000 0,01400824 0,08382205 GO:0032259|methylation, ! regulation of adaptive immune response GO:0002819 22 22 1,000 0,01400824 0,08355078 ! detection of external stimulus GO:0009581 23 22 1,000 0,01400824 0,08328126 ! positive regulation of lymphocyte differentiation GO:0045621 22 22 1,000 0,01400824 0,08301347 ! cytokinesis GO:0000910 23 22 1,000 0,01400824 0,0827474 ! purine ribonucleoside triphosphate metabolic process GO:0009205 62 62 2,000 0,01443818 0,08501457 ! regulation of lymphocyte activation GO:0051249 62 62 2,000 0,01443818 0,08474382 ! ribonucleoside triphosphate metabolic process GO:0009199 63 63 2,000 0,01507239 0,08818542 ! purine nucleoside triphosphate metabolic process GO:0009144 63 63 2,000 0,01507239 0,08790635 ! mitotic cell cycle checkpoint GO:0007093 24 23 1,000 0,0152615 0,08872856 ! monovalent inorganic cation homeostasis GO:0055067 23 23 1,000 0,0152615 0,08844953 ! Rho protein signal transduction GO:0007266 24 23 1,000 0,0152615 0,08817226 ! regulation of cytoskeleton organization GO:0051493 66 64 2,000 0,0157222 0,09055004 ! mitochondrial transport GO:0006839 24 24 1,000 0,01656122 0,09508515 ! regulation of action potential GO:0001508 24 24 1,000 0,01656122 0,09478986 ! gliogenesis GO:0042063 24 24 1,000 0,01656122 0,09449639 ! nucleotide catabolic process GO:0009166 24 24 1,000 0,01656122 0,09420474 ! maintenance of protein location GO:0045185 25 24 1,000 0,01656122 0,09391488 ! epithelial tube morphogenesis GO:0060562 25 24 1,000 0,01656122 0,09362679 ! nucleoside triphosphate metabolic process GO:0009141 66 66 2,000 0,01706881 0,09620126 ! negative regulation of protein metabolic process GO:0051248 66 66 2,000 0,01706881 0,09590796 ! striated muscle tissue development GO:0014706 69 67 2,000 0,01776567 0,09952017 ! Ras protein signal transduction GO:0007265 69 67 2,000 0,01776567 0,09921859 ! regulation of gene-specific transcription GO:0032583 25 25 1,000 0,01790657 0,09970336 ! regulation of intracellular protein transport GO:0033157 25 25 1,000 0,01790657 0,09940305 ! JAK-STAT cascade GO:0007259 26 25 1,000 0,01790657 0,09910454 ! response to radiation GO:0009314 70 68 2,000 0,01847829 0,10196253 ! regulation of leukocyte activation GO:0002694 69 69 2,000 0,01920668 0,10566539 ! double-strand break repair GO:0006302 27 26 1,000 0,01929673 0,10584488 ! response to insulin stimulus GO:0032868 28 26 1,000 0,01929673 0,1055308 ! maintenance of location in cell GO:0051651 27 26 1,000 0,01929673 0,10521858 ! muscle tissue development GO:0060537 72 70 2,000 0,01995086 0,10846442 ! regulation of cell migration GO:0030334 71 71 2,000 0,02071086 0,11226504 ! regulation of cell activation GO:0050865 71 71 2,000 0,02071086 0,11193582 ! regulation of nucleocytoplasmic transport GO:0046822 27 27 1,000 0,0207309 0,11171651 ! activation of caspase activity GO:0006919 27 27 1,000 0,0207309 0,11139081 ! mesenchymal cell development GO:0014031 29 27 1,000 0,0207309 0,111067 GO:0060485|mesenchyme development, GO:0048762|mesenchymal cell differentiation, ! keratinocyte differentiation GO:0030216 28 28 1,000 0,02220827 0,11863724 ! protein amino acid autophosphorylation GO:0046777 28 28 1,000 0,02220827 0,11829435 ! regulation of epithelial cell proliferation GO:0050678 29 29 1,000 0,02372807 0,12602543 ! regulation of gene expression, epigenetic GO:0040029 29 29 1,000 0,02372807 0,12566329 ! response to UV GO:0009411 29 29 1,000 0,02372807 0,12530322 ! response to oxidative stress GO:0006979 76 75 2,000 0,0239092 0,12589902 ! purine ribonucleotide metabolic process GO:0009150 75 75 2,000 0,0239092 0,12554033 ! response to reactive oxygen species GO:0000302 31 30 1,000 0,0252895 0,13241065 ! positive regulation of peptidase activity GO:0010952 30 30 1,000 0,0252895 0,13203555 GO:0043280|positive regulation of caspase activity, ! regulation of protein complex disassembly GO:0043244 30 30 1,000 0,0252895 0,13166257 ! positive regulation of protein amino acid phosphorylation GO:0001934 30 30 1,000 0,0252895 0,13129169 ! response to temperature stimulus GO:0009266 30 30 1,000 0,0252895 0,13092289 ! vesicle organization GO:0016050 30 30 1,000 0,0252895 0,13055616 ! regulation of protein modification process GO:0031399 79 78 2,000 0,0264743 0,13629089 ! regulation of translational initiation GO:0006446 31 31 1,000 0,02689181 0,1380546 ! skeletal muscle fiber development GO:0048741 31 31 1,000 0,02689181 0,13767112 ! membrane fusion GO:0006944 31 31 1,000 0,02689181 0,13728976 ! B cell activation GO:0042113 31 31 1,000 0,02689181 0,1369105 ! ion transmembrane transport GO:0034220 31 31 1,000 0,02689181 0,13653334 GO:0015985|energy coupled proton transport, down electrochemical gradient, GO:0015986|ATP synthesis coupled proton transport, ! aging GO:0007568 32 31 1,000 0,02689181 0,13615825 ! nucleoside metabolic process GO:0009116 31 31 1,000 0,02689181 0,13578521 ! regulation of DNA replication GO:0006275 32 31 1,000 0,02689181 0,13541421 ! regulation of intracellular transport GO:0032386 31 31 1,000 0,02689181 0,13504524 ! epidermal cell differentiation GO:0009913 31 31 1,000 0,02689181 0,13467827 ! regulation of locomotion GO:0040012 79 79 2,000 0,02736099 0,13665666 ! nuclear transport GO:0051169 79 79 2,000 0,02736099 0,13628732 GO:0006913|nucleocytoplasmic transport, ! regulation of cell motion GO:0051270 79 79 2,000 0,02736099 0,13591997 ! muscle fiber development GO:0048747 32 32 1,000 0,02853423 0,14136717 ! nuclear export GO:0051168 32 32 1,000 0,02853423 0,14098817 ! protein maturation by peptide bond cleavage GO:0051605 32 32 1,000 0,02853423 0,14061119 ! maintenance of location GO:0051235 33 32 1,000 0,02853423 0,14023623 ! lymphocyte activation GO:0046649 82 81 2,000 0,02918178 0,14303729 ! regulation of neuron apoptosis GO:0043523 34 33 1,000 0,03021602 0,14771384 ! ribonucleotide metabolic process GO:0009259 83 83 2,000 0,03106564 0,15146556 ! regulation of angiogenesis GO:0045765 35 34 1,000 0,03193643 0,15530036 ! response to metal ion GO:0010038 34 34 1,000 0,03193643 0,15489168 ! muscle cell differentiation GO:0042692 35 34 1,000 0,03193643 0,15448514 ! regulation of lipid metabolic process GO:0019216 34 34 1,000 0,03193643 0,15408072 ! response to peptide hormone stimulus GO:0043434 36 34 1,000 0,03193643 0,15367843 ! negative regulation of response to stimulus GO:0048585 34 34 1,000 0,03193643 0,15327822 ! detection of stimulus GO:0051606 36 34 1,000 0,03193643 0,1528801 ! positive regulation of phosphorylation GO:0042327 35 35 1,000 0,03369473 0,16087925 ! regulation of immune effector process GO:0002697 35 35 1,000 0,03369473 0,16046354 ! hydrogen transport GO:0006818 36 36 1,000 0,03549021 0,16857849 GO:0015992|proton transport, ! response to inorganic substance GO:0010035 36 36 1,000 0,03549021 0,16814512 ! positive regulation of cell migration GO:0030335 36 36 1,000 0,03549021 0,16771398 ! positive regulation of phosphorus metabolic process GO:0010562 36 36 1,000 0,03549021 0,16728505 GO:0045937|positive regulation of phosphate metabolic process, ! positive regulation of organelle organization GO:0010638 36 36 1,000 0,03549021 0,1668583 ! heterocycle catabolic process GO:0046700 36 36 1,000 0,03549021 0,16643372 ! activation of immune response GO:0002253 36 36 1,000 0,03549021 0,1660113 ! male gamete generation GO:0048232 90 88 2,000 0,03604984 0,16820215 GO:0007283|spermatogenesis, ! meiosis GO:0007126 37 37 1,000 0,03732214 0,17369876 GO:0051327|M phase of meiotic cell cycle, ! chromosome segregation GO:0007059 38 38 1,000 0,03918983 0,18193163 ! meiotic cell cycle GO:0051321 38 38 1,000 0,03918983 0,18147451 ! regulation of homeostatic process GO:0032844 38 38 1,000 0,03918983 0,18101969 ! DNA replication GO:0006260 91 91 2,000 0,03922718 0,18073922 ! rRNA transcription GO:0009303 5 5 0,000 0,04075534 0,18731196 ! positive regulation of protein ubiquitination GO:0031398 5 5 0,000 0,04075534 0,18684601 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 5 5 0,000 0,04075534 0,18638237 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 5 5 0,000 0,04075534 0,18592103 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! neuron fate specification GO:0048665 5 5 0,000 0,04075534 0,18546196 ! hemoglobin biosynthetic process GO:0042541 5 5 0,000 0,04075534 0,18500516 ! reproductive cellular process GO:0048610 5 5 0,000 0,04075534 0,1845506 ! positive regulation of glucose metabolic process GO:0010907 5 5 0,000 0,04075534 0,18409827 ! negative regulation of blood pressure GO:0045776 6 5 0,000 0,04075534 0,18364815 ! prostate gland development GO:0030850 5 5 0,000 0,04075534 0,18320023 ! metencephalon development GO:0022037 5 5 0,000 0,04075534 0,18275449 ! water transport GO:0006833 5 5 0,000 0,04075534 0,18231091 GO:0042044|fluid transport, ! forebrain regionalization GO:0021871 5 5 0,000 0,04075534 0,18186948 ! DNA synthesis during DNA repair GO:0000731 5 5 0,000 0,04075534 0,18143018 ! regulation of cellular amine metabolic process GO:0033238 5 5 0,000 0,04075534 0,180993 GO:0042053|regulation of dopamine metabolic process, GO:0042069|regulation of catecholamine metabolic process, ! meiotic prophase I GO:0007128 5 5 0,000 0,04075534 0,18055792 GO:0051324|prophase, ! cell volume homeostasis GO:0006884 5 5 0,000 0,04075534 0,18012493 ! regulation of epidermal growth factor receptor activity GO:0007176 5 5 0,000 0,04075534 0,17969401 GO:0010469|regulation of receptor activity, ! regulation of long-term neuronal synaptic plasticity GO:0048169 5 5 0,000 0,04075534 0,17926514 ! filopodium assembly GO:0046847 7 5 0,000 0,04075534 0,17883832 GO:0030035|microspike assembly, ! CTP metabolic process GO:0046036 5 5 0,000 0,04075534 0,17841353 GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0006241|CTP biosynthetic process, ! Golgi to endosome transport GO:0006895 5 5 0,000 0,04075534 0,17799075 ! GTP metabolic process GO:0046039 5 5 0,000 0,04075534 0,17756996 ! establishment of tissue polarity GO:0007164 5 5 0,000 0,04075534 0,17715117 ! mRNA stabilization GO:0048255 5 5 0,000 0,04075534 0,17673434 GO:0043489|RNA stabilization, ! positive regulation of cell-cell adhesion GO:0022409 5 5 0,000 0,04075534 0,17631947 ! regulation of neurotransmitter secretion GO:0046928 5 5 0,000 0,04075534 0,17590654 GO:0001956|positive regulation of neurotransmitter secretion, ! neurotransmitter uptake GO:0001504 5 5 0,000 0,04075534 0,17549555 ! social behavior GO:0035176 5 5 0,000 0,04075534 0,17508647 ! macrophage chemotaxis GO:0048246 6 5 0,000 0,04075534 0,17467929 ! memory GO:0007613 5 5 0,000 0,04075534 0,174274 ! dopamine receptor signaling pathway GO:0007212 5 5 0,000 0,04075534 0,17387059 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 5 5 0,000 0,04075534 0,17346904 ! membrane hyperpolarization GO:0060081 5 5 0,000 0,04075534 0,17306934 ! response to lipid GO:0033993 5 5 0,000 0,04075534 0,17267148 ! erythrocyte maturation GO:0043249 5 5 0,000 0,04075534 0,17227545 ! hippocampus development GO:0021766 6 5 0,000 0,04075534 0,17188122 ! regulation of carbohydrate biosynthetic process GO:0043255 5 5 0,000 0,04075534 0,1714888 ! glucocorticoid metabolic process GO:0008211 5 5 0,000 0,04075534 0,17109817 ! middle ear morphogenesis GO:0042474 5 5 0,000 0,04075534 0,17070931 ! mechanosensory behavior GO:0007638 5 5 0,000 0,04075534 0,17032221 ! heart looping GO:0001947 5 5 0,000 0,04075534 0,16993687 ! negative regulation of endocytosis GO:0045806 5 5 0,000 0,04075534 0,16955326 ! response to interferon-gamma GO:0034341 5 5 0,000 0,04075534 0,16917138 ! pseudouridine synthesis GO:0001522 5 5 0,000 0,04075534 0,16879122 ! endocrine pancreas development GO:0031018 5 5 0,000 0,04075534 0,16841277 ! pH reduction GO:0045851 5 5 0,000 0,04075534 0,16803601 GO:0051452|intracellular pH reduction, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 5 5 0,000 0,04075534 0,16766093 ! lipopolysaccharide metabolic process GO:0008653 5 5 0,000 0,04075534 0,16728752 ! positive regulation of chemokine biosynthetic process GO:0045080 5 5 0,000 0,04075534 0,16691577 ! sphingoid biosynthetic process GO:0046520 5 5 0,000 0,04075534 0,16654566 GO:0046513|ceramide biosynthetic process, ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 5 5 0,000 0,04075534 0,1661772 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! photoreceptor cell maintenance GO:0045494 5 5 0,000 0,04075534 0,16581036 ! adrenal gland development GO:0030325 5 5 0,000 0,04075534 0,16544514 ! regulation of cardiac muscle hypertrophy GO:0010611 5 5 0,000 0,04075534 0,16508153 GO:0010612|regulation of cardiac muscle adaptation, GO:0014743|regulation of muscle hypertrophy, GO:0043502|regulation of muscle adaptation, ! melanocyte differentiation GO:0030318 5 5 0,000 0,04075534 0,16471951 GO:0050931|pigment cell differentiation, ! ovulation GO:0030728 5 5 0,000 0,04075534 0,16435907 ! astrocyte differentiation GO:0048708 5 5 0,000 0,04075534 0,16400021 ! mitochondrial respiratory chain complex assembly GO:0033108 5 5 0,000 0,04075534 0,16364291 GO:0032981|mitochondrial respiratory chain complex I assembly, GO:0010257|NADH dehydrogenase complex assembly, ! pituitary gland development GO:0021983 5 5 0,000 0,04075534 0,16328716 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 5 5 0,000 0,04075534 0,16293296 GO:0033135|regulation of peptidyl-serine phosphorylation, ! tyrosine metabolic process GO:0006570 5 5 0,000 0,04075534 0,16258029 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 5 5 0,000 0,04075534 0,16222915 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, GO:0009164|nucleoside catabolic process, ! microtubule nucleation GO:0007020 5 5 0,000 0,04075534 0,16187951 ! regulation of interleukin-6 biosynthetic process GO:0045408 5 5 0,000 0,04075534 0,16153139 ! regulation of interleukin-8 biosynthetic process GO:0045414 5 5 0,000 0,04075534 0,16118475 ! indolalkylamine metabolic process GO:0006586 5 5 0,000 0,04075534 0,1608396 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! muscle cell migration GO:0014812 5 5 0,000 0,04075534 0,16049593 ! phasic smooth muscle contraction GO:0014821 5 5 0,000 0,04075534 0,16015372 ! central nervous system neuron axonogenesis GO:0021955 6 5 0,000 0,04075534 0,15981297 GO:0021952|central nervous system projection neuron axonogenesis, ! sister chromatid cohesion GO:0007062 5 5 0,000 0,04075534 0,15947366 ! response to ATP GO:0033198 5 5 0,000 0,04075534 0,15913579 ! regulation of type I interferon production GO:0032479 5 5 0,000 0,04075534 0,15879935 ! regulation of appetite GO:0032098 5 5 0,000 0,04075534 0,15846433 GO:0032095|regulation of response to food, ! paraxial mesoderm development GO:0048339 5 5 0,000 0,04075534 0,15813073 ! regulation of phospholipase A2 activity GO:0032429 5 5 0,000 0,04075534 0,15779852 ! regulation of the force of heart contraction GO:0002026 5 5 0,000 0,04075534 0,1574677 ! maintenance of protein location in nucleus GO:0051457 5 5 0,000 0,04075534 0,15713827 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,04075534 0,15681022 ! receptor clustering GO:0043113 5 5 0,000 0,04075534 0,15648353 ! neurotransmitter biosynthetic process GO:0042136 6 5 0,000 0,04075534 0,1561582 ! fear response GO:0042596 5 5 0,000 0,04075534 0,15583422 ! actin cytoskeleton reorganization GO:0031532 5 5 0,000 0,04075534 0,15551158 ! lens development in camera-type eye GO:0002088 5 5 0,000 0,04075534 0,15519028 ! retinol metabolic process GO:0042572 5 5 0,000 0,04075534 0,1548703 ! corticosteroid receptor signaling pathway GO:0031958 5 5 0,000 0,04075534 0,15455164 GO:0042921|glucocorticoid receptor signaling pathway, ! temperature homeostasis GO:0001659 5 5 0,000 0,04075534 0,15423428 ! positive regulation of exocytosis GO:0045921 6 5 0,000 0,04075534 0,15391823 ! parturition GO:0007567 5 5 0,000 0,04075534 0,15360347 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,04075534 0,15328999 ! regulation of vascular endothelial growth factor production GO:0010574 5 5 0,000 0,04075534 0,15297779 ! Schwann cell differentiation GO:0014037 5 5 0,000 0,04075534 0,15266686 ! acyl-CoA metabolic process GO:0006637 5 5 0,000 0,04075534 0,15235719 ! wound healing, spreading of epidermal cells GO:0035313 5 5 0,000 0,04075534 0,15204877 ! protein heterooligomerization GO:0051291 5 5 0,000 0,04075534 0,15174161 ! regulation of gliogenesis GO:0014013 5 5 0,000 0,04075534 0,15143567 GO:0045685|regulation of glial cell differentiation, ! positive regulation of peptide secretion GO:0002793 5 5 0,000 0,04075534 0,15113098 ! response to UV-B GO:0010224 5 5 0,000 0,04075534 0,1508275 ! oligodendrocyte development GO:0014003 5 5 0,000 0,04075534 0,15052524 ! hyaluronan metabolic process GO:0030212 5 5 0,000 0,04075534 0,15022419 ! activated T cell proliferation GO:0050798 5 5 0,000 0,04075534 0,14992434 ! interaction with symbiont GO:0051702 5 5 0,000 0,04075534 0,14962569 ! cellular extravasation GO:0045123 5 5 0,000 0,04075534 0,14932822 ! positive regulation of axonogenesis GO:0050772 5 5 0,000 0,04075534 0,14903193 ! peptidyl-asparagine modification GO:0018196 5 5 0,000 0,04075534 0,14873682 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! positive regulation of phagocytosis GO:0050766 5 5 0,000 0,04075534 0,14844287 ! regulation of insulin receptor signaling pathway GO:0046626 5 5 0,000 0,04075534 0,14815009 ! antigen processing and presentation of exogenous antigen GO:0019884 5 5 0,000 0,04075534 0,14785845 ! enucleate erythrocyte differentiation GO:0043353 6 5 0,000 0,04075534 0,14756797 ! response to amine stimulus GO:0014075 5 5 0,000 0,04075534 0,14727862 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 5 5 0,000 0,04075534 0,1469904 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 5 5 0,000 0,04075534 0,14670331 ! synaptic vesicle exocytosis GO:0016079 6 5 0,000 0,04075534 0,14641734 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 5 5 0,000 0,04075534 0,14613248 ! glycosylceramide metabolic process GO:0006677 5 5 0,000 0,04075534 0,14584873 ! neuron recognition GO:0008038 5 5 0,000 0,04075534 0,14556607 ! negative regulation of focal adhesion formation GO:0051895 6 5 0,000 0,04075534 0,14528452 ! decidualization GO:0046697 5 5 0,000 0,04075534 0,14500404 ! hair follicle maturation GO:0048820 5 5 0,000 0,04075534 0,14472465 ! phosphatidylinositol biosynthetic process GO:0006661 5 5 0,000 0,04075534 0,14444634 ! regulation of mitochondrial membrane potential GO:0051881 5 5 0,000 0,04075534 0,14416909 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 0,04075534 0,1438929 GO:0009155|purine deoxyribonucleotide catabolic process, ! regulation of interleukin-12 production GO:0032655 5 5 0,000 0,04075534 0,14361777 ! positive regulation of interleukin-6 production GO:0032755 5 5 0,000 0,04075534 0,14334369 ! positive regulation of monooxygenase activity GO:0032770 5 5 0,000 0,04075534 0,14307066 ! postreplication repair GO:0006301 5 5 0,000 0,04075534 0,14279866 ! spinal cord motor neuron differentiation GO:0021522 5 5 0,000 0,04075534 0,14252769 GO:0021517|ventral spinal cord development, ! cellular pigmentation GO:0033059 5 5 0,000 0,04075534 0,14225776 ! histone methylation GO:0016571 5 5 0,000 0,04075534 0,14198884 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,04075534 0,14172093 ! positive regulation of interferon-gamma production GO:0032729 5 5 0,000 0,04075534 0,14145404 ! negative regulation of tumor necrosis factor production GO:0032720 5 5 0,000 0,04075534 0,14118815 ! intracellular cholesterol transport GO:0032367 5 5 0,000 0,04075534 0,14092325 GO:0032366|intracellular sterol transport, ! regulation of mast cell activation GO:0033003 5 5 0,000 0,04075534 0,14065935 ! morphogenesis of a polarized epithelium GO:0001738 5 5 0,000 0,04075534 0,14039644 ! regulation of hormone metabolic process GO:0032350 5 5 0,000 0,04075534 0,14013451 ! regulation of transcription from RNA polymerase III promoter GO:0006359 5 5 0,000 0,04075534 0,13987355 ! regulation of inflammatory response to antigenic stimulus GO:0002861 5 5 0,000 0,04075534 0,13961356 ! sterol catabolic process GO:0016127 5 5 0,000 0,04075534 0,13935454 GO:0006707|cholesterol catabolic process, ! negative regulation of oxidoreductase activity GO:0051354 5 5 0,000 0,04075534 0,13909647 ! detection of biotic stimulus GO:0009595 5 5 0,000 0,04075534 0,13883936 ! regulation of immune response to tumor cell GO:0002837 5 5 0,000 0,04075534 0,1385832 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 5 5 0,000 0,04075534 0,13832798 ! zymogen activation GO:0031638 5 5 0,000 0,04075534 0,1380737 ! positive regulation of interleukin-1 beta secretion GO:0050718 5 5 0,000 0,04075534 0,13782036 ! cellular response to nutrient GO:0031670 5 5 0,000 0,04075534 0,13756794 ! peptidyl-lysine modification GO:0018205 5 5 0,000 0,04075534 0,13731644 ! peptidyl-histidine modification GO:0018202 5 5 0,000 0,04075534 0,13706587 ! nucleosome positioning GO:0016584 5 5 0,000 0,04075534 0,1368162 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 5 5 0,000 0,04075534 0,13656744 ! negative regulation of neurological system process GO:0031645 5 5 0,000 0,04075534 0,13631959 ! regulation of myoblast differentiation GO:0045661 5 5 0,000 0,04075534 0,13607264 ! glutathione biosynthetic process GO:0006750 5 5 0,000 0,04075534 0,13582657 ! NADPH regeneration GO:0006740 5 5 0,000 0,04075534 0,1355814 GO:0006098|pentose-phosphate shunt, ! positive regulation of erythrocyte differentiation GO:0045648 5 5 0,000 0,04075534 0,13533711 ! positive regulation of epidermis development GO:0045684 5 5 0,000 0,04075534 0,1350937 ! positive regulation of leukocyte chemotaxis GO:0002690 5 5 0,000 0,04075534 0,13485116 GO:0002688|regulation of leukocyte chemotaxis, ! musculoskeletal movement GO:0050881 5 5 0,000 0,04075534 0,13460949 GO:0050879|multicellular organismal movement, ! neuromuscular process controlling posture GO:0050884 5 5 0,000 0,04075534 0,13436868 ! regulation of epidermal cell differentiation GO:0045604 5 5 0,000 0,04075534 0,13412874 ! activation of NF-kappaB-inducing kinase activity GO:0007250 5 5 0,000 0,04075534 0,13388965 ! negative regulation of glucose transport GO:0010829 5 5 0,000 0,04075534 0,13365141 GO:0046325|negative regulation of glucose import, ! positive regulation of T-helper cell differentiation GO:0045624 5 5 0,000 0,04075534 0,13341402 GO:0045622|regulation of T-helper cell differentiation, ! oocyte differentiation GO:0009994 5 5 0,000 0,04075534 0,13317747 GO:0048599|oocyte development, ! dopamine biosynthetic process GO:0042416 5 5 0,000 0,04075534 0,13294176 ! regulation of protein homodimerization activity GO:0043496 6 5 0,000 0,04075534 0,13270688 ! spleen development GO:0048536 5 5 0,000 0,04075534 0,13247283 ! male genitalia development GO:0030539 5 5 0,000 0,04075534 0,1322396 ! nicotinamide nucleotide biosynthetic process GO:0019359 5 5 0,000 0,04075534 0,1320072 ! quaternary ammonium group transport GO:0015697 5 5 0,000 0,04075534 0,1317756 ! thyroid hormone metabolic process GO:0042403 5 5 0,000 0,04075534 0,13154482 ! leukocyte mediated cytotoxicity GO:0001909 5 5 0,000 0,04075534 0,13131485 ! positive regulation of viral reproduction GO:0048524 5 5 0,000 0,04075534 0,13108568 ! removal of superoxide radicals GO:0019430 6 5 0,000 0,04075534 0,13085731 ! myeloid cell homeostasis GO:0002262 5 5 0,000 0,04075534 0,13062973 ! regulation of fatty acid oxidation GO:0046320 5 5 0,000 0,04075534 0,13040294 ! regulation of Rac protein signal transduction GO:0035020 5 5 0,000 0,04075534 0,13017694 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,04075534 0,12995172 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 5 5 0,000 0,04075534 0,12972728 ! blastocyst formation GO:0001825 5 5 0,000 0,04075534 0,12950361 ! regulation of fibrinolysis GO:0051917 5 5 0,000 0,04075534 0,12928071 ! embryonic gut development GO:0048566 5 5 0,000 0,04075534 0,12905858 ! negative regulation of organic acid transport GO:0032891 5 5 0,000 0,04075534 0,12883721 ! pyrimidine base metabolic process GO:0006206 5 5 0,000 0,04075534 0,1286166 ! activation of innate immune response GO:0002218 5 5 0,000 0,04075534 0,12839674 GO:0002758|innate immune response-activating signal transduction, ! positive regulation of blood vessel endothelial cell migration GO:0043536 5 5 0,000 0,04075534 0,12817764 ! catecholamine transport GO:0051937 5 5 0,000 0,04075534 0,12795928 ! negative regulation of blood vessel endothelial cell migration GO:0043537 5 5 0,000 0,04075534 0,12774166 ! regulation of NF-kappaB import into nucleus GO:0042345 5 5 0,000 0,04075534 0,12752478 ! muscle adaptation GO:0043500 5 5 0,000 0,04075534 0,12730864 ! positive regulation of actin filament bundle formation GO:0032233 5 5 0,000 0,04075534 0,12709322 ! embryonic heart tube development GO:0035050 5 5 0,000 0,04075534 0,12687854 ! cardiac cell differentiation GO:0035051 6 5 0,000 0,04075534 0,12666458 ! positive regulation of homeostatic process GO:0032846 5 5 0,000 0,04075534 0,12645134 ! defense response to fungus GO:0050832 5 5 0,000 0,04075534 0,12623881 ! lysogeny GO:0030069 5 5 0,000 0,04075534 0,126027 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 5 5 0,000 0,04075534 0,1258159 ! positive regulation of smooth muscle contraction GO:0045987 5 5 0,000 0,04075534 0,12560551 ! response to nicotine GO:0035094 5 5 0,000 0,04075534 0,12539582 ! mitochondrion localization GO:0051646 5 5 0,000 0,04075534 0,12518682 ! nucleus localization GO:0051647 5 5 0,000 0,04075534 0,12497853 ! regulation of synapse structure and activity GO:0050803 5 5 0,000 0,04075534 0,12477092 ! positive regulation of protein modification process GO:0031401 39 39 1,000 0,04109258 0,12559472 ! response to unfolded protein GO:0006986 39 39 1,000 0,04109258 0,12538678 ! nucleotide-excision repair GO:0006289 40 39 1,000 0,04109258 0,12517953 ! regulation of MAPKKK cascade GO:0043408 41 39 1,000 0,04109258 0,12497297 ! positive regulation of T cell activation GO:0050870 39 39 1,000 0,04109258 0,12476708 ! protein oligomerization GO:0051259 39 39 1,000 0,04109258 0,12456187 ! positive regulation of cell motion GO:0051272 39 39 1,000 0,04109258 0,12435734 ! blood vessel development GO:0001568 95 94 2,000 0,04254318 0,12853621 ! vasculature development GO:0001944 97 96 2,000 0,04483019 0,1352243 ! cell cycle checkpoint GO:0000075 42 41 1,000 0,04500051 0,13551623 ! elevation of cytosolic calcium ion concentration GO:0007204 41 41 1,000 0,04500051 0,13529516 ! cytosolic calcium ion homeostasis GO:0051480 42 42 1,000 0,04700434 0,14108959 ! protein ubiquitination GO:0016567 43 42 1,000 0,04700434 0,14086017 ! response to protein stimulus GO:0051789 42 42 1,000 0,04700434 0,1406315 ! one-carbon metabolic process GO:0006730 42 42 1,000 0,04700434 0,14040358 ! anti-apoptosis GO:0006916 100 99 2,000 0,04837405 0,14426113 ! axon extension GO:0048675 7 6 0,000 0,04870835 0,14502341 ! oligosaccharide biosynthetic process GO:0009312 6 6 0,000 0,04870835 0,1447895 ! N-terminal protein amino acid modification GO:0031365 6 6 0,000 0,04870835 0,14455635 GO:0018409|peptide or protein amino-terminal blocking, ! tRNA modification GO:0006400 6 6 0,000 0,04870835 0,14432394 ! somatic diversification of immune receptors via somatic mutation GO:0002566 6 6 0,000 0,04870835 0,14409228 GO:0016446|somatic hypermutation of immunoglobulin genes, ! 'de novo' posttranslational protein folding GO:0051084 6 6 0,000 0,04870835 0,14386137 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 6 6 0,000 0,04870835 0,14363119 ! negative regulation of cellular catabolic process GO:0031330 6 6 0,000 0,04870835 0,14340175 ! virus-host interaction GO:0019048 6 6 0,000 0,04870835 0,14317303 ! myotube differentiation GO:0014902 6 6 0,000 0,04870835 0,14294505 ! bone remodeling GO:0046849 6 6 0,000 0,04870835 0,14271779 ! N-glycan processing GO:0006491 6 6 0,000 0,04870835 0,14249126 ! glycosaminoglycan catabolic process GO:0006027 6 6 0,000 0,04870835 0,14226544 ! negative regulation of JAK-STAT cascade GO:0046426 6 6 0,000 0,04870835 0,14204034 ! retina development in camera-type eye GO:0060041 6 6 0,000 0,04870835 0,14181594 ! RNA methylation GO:0001510 6 6 0,000 0,04870835 0,14159226 ! cartilage condensation GO:0001502 7 6 0,000 0,04870835 0,14136928 ! regulation of activated T cell proliferation GO:0046006 6 6 0,000 0,04870835 0,141147 ! regulation of positive chemotaxis GO:0050926 6 6 0,000 0,04870835 0,14092542 GO:0050927|positive regulation of positive chemotaxis, ! artery development GO:0060840 6 6 0,000 0,04870835 0,14070453 GO:0048844|artery morphogenesis, ! positive regulation of neurotransmitter transport GO:0051590 6 6 0,000 0,04870835 0,14048434 ! bile acid metabolic process GO:0008206 6 6 0,000 0,04870835 0,14026483 ! androgen metabolic process GO:0008209 6 6 0,000 0,04870835 0,14004601 ! estrogen metabolic process GO:0008210 6 6 0,000 0,04870835 0,13982787 ! limbic system development GO:0021761 7 6 0,000 0,04870835 0,13961041 ! cytoplasmic sequestering of transcription factor GO:0042994 6 6 0,000 0,04870835 0,13939362 ! positive regulation of transcription factor import into nucleus GO:0042993 6 6 0,000 0,04870835 0,13917751 ! positive regulation of heart contraction GO:0045823 6 6 0,000 0,04870835 0,13896206 ! positive regulation of gene expression, epigenetic GO:0045815 6 6 0,000 0,04870835 0,13874728 ! pathogenesis GO:0009405 6 6 0,000 0,04870835 0,13853317 ! regulation of chemokine biosynthetic process GO:0045073 6 6 0,000 0,04870835 0,13831971 ! nerve growth factor receptor signaling pathway GO:0048011 6 6 0,000 0,04870835 0,13810691 ! inositol phosphate-mediated signaling GO:0048016 6 6 0,000 0,04870835 0,13789477 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 6 6 0,000 0,04870835 0,13768327 ! arginine metabolic process GO:0006525 6 6 0,000 0,04870835 0,13747242 GO:0006527|arginine catabolic process, ! regulation of catecholamine secretion GO:0050433 6 6 0,000 0,04870835 0,13726222 ! glutamate catabolic process GO:0006538 7 6 0,000 0,04870835 0,13705266 ! telomere maintenance via telomerase GO:0007004 6 6 0,000 0,04870835 0,13684374 GO:0010833|telomere maintenance via telomere lengthening, ! L-phenylalanine metabolic process GO:0006558 6 6 0,000 0,04870835 0,13663545 GO:0006559|L-phenylalanine catabolic process, ! glucan biosynthetic process GO:0009250 6 6 0,000 0,04870835 0,1364278 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 6 6 0,000 0,04870835 0,13622078 ! V(D)J recombination GO:0033151 6 6 0,000 0,04870835 0,13601438 ! focal adhesion formation GO:0048041 7 6 0,000 0,04870835 0,13580861 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 0,04870835 0,13560346 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 6 6 0,000 0,04870835 0,13539893 ! negative regulation of endothelial cell migration GO:0010596 6 6 0,000 0,04870835 0,13519502 ! regulation of heart rate GO:0002027 6 6 0,000 0,04870835 0,13499172 ! lipid digestion GO:0044241 6 6 0,000 0,04870835 0,13478903 ! asymmetric protein localization GO:0008105 6 6 0,000 0,04870835 0,13458695 ! retrograde transport, endosome to Golgi GO:0042147 6 6 0,000 0,04870835 0,13438547 ! phagocytosis, engulfment GO:0006911 6 6 0,000 0,04870835 0,13418459 ! Rac protein signal transduction GO:0016601 6 6 0,000 0,04870835 0,13398432 ! regulation of vascular permeability GO:0043114 6 6 0,000 0,04870835 0,13378464 ! regulation of calcium ion transport into cytosol GO:0010522 6 6 0,000 0,04870835 0,13358555 ! ruffle organization GO:0031529 6 6 0,000 0,04870835 0,13338706 ! peptidyl-serine phosphorylation GO:0018105 6 6 0,000 0,04870835 0,13318916 ! preassembly of GPI anchor in ER membrane GO:0016254 6 6 0,000 0,04870835 0,13299184 ! retinoic acid metabolic process GO:0042573 6 6 0,000 0,04870835 0,13279511 ! neutral amino acid transport GO:0015804 6 6 0,000 0,04870835 0,13259896 ! L-amino acid transport GO:0015807 6 6 0,000 0,04870835 0,13240338 ! bone mineralization GO:0030282 6 6 0,000 0,04870835 0,13220838 GO:0031214|biomineral formation, ! rRNA modification GO:0000154 6 6 0,000 0,04870835 0,13201396 ! negative regulation of ossification GO:0030279 6 6 0,000 0,04870835 0,13182011 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 6 6 0,000 0,04870835 0,13162682 GO:0002717|positive regulation of natural killer cell mediated immunity, GO:0002715|regulation of natural killer cell mediated immunity, GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of bone resorption GO:0045124 6 6 0,000 0,04870835 0,1314341 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 7 6 0,000 0,04870835 0,13124195 ! purine base biosynthetic process GO:0009113 6 6 0,000 0,04870835 0,13105035 ! negative regulation of axonogenesis GO:0050771 7 6 0,000 0,04870835 0,13085932 ! regulation of phagocytosis GO:0050764 6 6 0,000 0,04870835 0,13066884 ! regulation of organ growth GO:0046620 6 6 0,000 0,04870835 0,13047891 ! regulation of circadian rhythm GO:0042752 6 6 0,000 0,04870835 0,13028954 ! response to dsRNA GO:0043331 6 6 0,000 0,04870835 0,13010071 ! DNA unwinding during replication GO:0006268 6 6 0,000 0,04870835 0,12991244 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 6 6 0,000 0,04870835 0,1297247 GO:0009147|pyrimidine nucleoside triphosphate metabolic process, ! genitalia development GO:0048806 6 6 0,000 0,04870835 0,12953751 ! sphingomyelin metabolic process GO:0006684 6 6 0,000 0,04870835 0,12935085 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 6 6 0,000 0,04870835 0,12916474 ! positive regulation of B cell differentiation GO:0045579 6 6 0,000 0,04870835 0,12897916 ! multicellular organismal aging GO:0010259 6 6 0,000 0,04870835 0,12879411 ! regulation of focal adhesion formation GO:0051893 7 6 0,000 0,04870835 0,12860959 ! respiratory chain complex IV assembly GO:0008535 6 6 0,000 0,04870835 0,1284256 ! erythrocyte development GO:0048821 6 6 0,000 0,04870835 0,12824213 ! renal water homeostasis GO:0003091 6 6 0,000 0,04870835 0,12805919 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 6 6 0,000 0,04870835 0,12787677 GO:0043372|positive regulation of CD4-positive, alpha beta T cell differentiation, ! ribosomal large subunit biogenesis GO:0042273 6 6 0,000 0,04870835 0,12769487 ! regulation of Rho GTPase activity GO:0032319 6 6 0,000 0,04870835 0,12751348 ! ribosome assembly GO:0042255 6 6 0,000 0,04870835 0,12733261 ! positive regulation of Ras GTPase activity GO:0032320 6 6 0,000 0,04870835 0,12715226 ! diencephalon development GO:0021536 6 6 0,000 0,04870835 0,12697241 ! fucose catabolic process GO:0019317 6 6 0,000 0,04870835 0,12679307 GO:0042355|L-fucose catabolic process, ! regulation of lipid transport GO:0032368 6 6 0,000 0,04870835 0,12661423 ! regulation of cell division GO:0051302 6 6 0,000 0,04870835 0,12643591 ! positive regulation of interleukin-1 secretion GO:0050716 6 6 0,000 0,04870835 0,12625808 ! cellular metabolic compound salvage GO:0043094 6 6 0,000 0,04870835 0,12608075 ! regulation of T-helper 2 type immune response GO:0002828 6 6 0,000 0,04870835 0,12590392 ! salivary gland morphogenesis GO:0007435 6 6 0,000 0,04870835 0,12572758 ! neuroblast proliferation GO:0007405 6 6 0,000 0,04870835 0,12555174 ! regulation of interleukin-1 beta secretion GO:0050706 6 6 0,000 0,04870835 0,12537639 ! nitric oxide mediated signal transduction GO:0007263 6 6 0,000 0,04870835 0,12520152 ! regulation of glucose transport GO:0010827 6 6 0,000 0,04870835 0,12502715 GO:0046324|regulation of glucose import, ! intestinal absorption GO:0050892 6 6 0,000 0,04870835 0,12485326 ! methionine biosynthetic process GO:0009086 6 6 0,000 0,04870835 0,12467985 ! glutamine family amino acid biosynthetic process GO:0009084 6 6 0,000 0,04870835 0,12450692 ! serine family amino acid biosynthetic process GO:0009070 6 6 0,000 0,04870835 0,12433448 ! thymus development GO:0048538 6 6 0,000 0,04870835 0,12416251 ! lymph node development GO:0048535 6 6 0,000 0,04870835 0,12399101 ! organic cation transport GO:0015695 6 6 0,000 0,04870835 0,12381999 ! negative regulation of BMP signaling pathway GO:0030514 6 6 0,000 0,04870835 0,12364944 ! regulation of RNA splicing GO:0043484 6 6 0,000 0,04870835 0,12347936 ! regulation of cellular carbohydrate catabolic process GO:0043471 6 6 0,000 0,04870835 0,12330974 GO:0043470|regulation of carbohydrate catabolic process, GO:0006110|regulation of glycolysis, ! positive regulation of JNK cascade GO:0046330 7 6 0,000 0,04870835 0,12314059 ! sperm-egg recognition GO:0035036 7 6 0,000 0,04870835 0,12297191 GO:0007339|binding of sperm to zona pellucida, ! germ cell migration GO:0008354 6 6 0,000 0,04870835 0,12280368 ! establishment or maintenance of apical/basal cell polarity GO:0035088 6 6 0,000 0,04870835 0,12263592 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 6 6 0,000 0,04870835 0,12246861 ! regulation of synaptic transmission, GABAergic GO:0032228 6 6 0,000 0,04870835 0,12230176 ! regulation of amino acid transport GO:0051955 6 6 0,000 0,04870835 0,12213536 ! maternal placenta development GO:0001893 6 6 0,000 0,04870835 0,12196942 ! localization within membrane GO:0051668 6 6 0,000 0,04870835 0,12180392 ! response to hormone stimulus GO:0009725 102 100 2,000 0,04958531 0,12382891 ! muscle organ development GO:0007517 102 100 2,000 0,04958531 0,12366134 ! negative regulation of transcription from RNA polymerase II promoter GO:0000122 103 100 2,000 0,04958531 0,12349423 ! protein import into nucleus GO:0006606 44 44 1,000 0,05110846 0,1271159 ! positive regulation of lymphocyte activation GO:0051251 44 44 1,000 0,05110846 0,12694459 ! homophilic cell adhesion GO:0007156 45 45 1,000 0,05320743 0,13198022 ! phosphoinositide-mediated signaling GO:0048015 45 45 1,000 0,05320743 0,13180283 ! nuclear import GO:0051170 45 45 1,000 0,05320743 0,13162591 ! Wnt receptor signaling pathway GO:0016055 46 45 1,000 0,05320743 0,13144947 ! protein processing GO:0016485 45 45 1,000 0,05320743 0,1312735 ! tube morphogenesis GO:0035239 47 46 1,000 0,05533684 0,13634465 ! regulation of membrane potential GO:0042391 46 46 1,000 0,05533684 0,13616262 ! respiratory burst GO:0045730 7 7 0,000 0,05659657 0,13907664 ! negative regulation of cell projection organization GO:0031345 8 7 0,000 0,05659657 0,13889145 ! positive regulation of blood pressure GO:0045777 7 7 0,000 0,05659657 0,13870676 ! positive regulation of cellular catabolic process GO:0031331 7 7 0,000 0,05659657 0,13852255 ! pteridine and derivative biosynthetic process GO:0042559 7 7 0,000 0,05659657 0,13833884 ! regulation of chemokine production GO:0032642 7 7 0,000 0,05659657 0,13815561 ! double-strand break repair via homologous recombination GO:0000724 7 7 0,000 0,05659657 0,13797286 GO:0000725|recombinational repair, ! positive regulation of GTPase activity GO:0043547 7 7 0,000 0,05659657 0,1377906 ! SMAD protein nuclear translocation GO:0007184 7 7 0,000 0,05659657 0,13760882 ! cellular protein complex disassembly GO:0043624 8 7 0,000 0,05659657 0,13742751 GO:0043241|protein complex disassembly, ! hair follicle morphogenesis GO:0031069 7 7 0,000 0,05659657 0,13724669 ! gene silencing by RNA GO:0031047 7 7 0,000 0,05659657 0,13706634 ! regulation of receptor-mediated endocytosis GO:0048259 7 7 0,000 0,05659657 0,13688646 ! regulation of neurotransmitter transport GO:0051588 7 7 0,000 0,05659657 0,13670705 ! axis specification GO:0009798 7 7 0,000 0,05659657 0,13652812 ! negative regulation of muscle cell differentiation GO:0051148 7 7 0,000 0,05659657 0,13634965 ! visual behavior GO:0007632 7 7 0,000 0,05659657 0,13617165 GO:0008542|visual learning, ! startle response GO:0001964 7 7 0,000 0,05659657 0,13599411 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 8 7 0,000 0,05659657 0,13581703 ! positive regulation of lipid metabolic process GO:0045834 7 7 0,000 0,05659657 0,13564042 ! negative regulation of lipid metabolic process GO:0045833 7 7 0,000 0,05659657 0,13546426 ! regulation of interferon-gamma biosynthetic process GO:0045072 7 7 0,000 0,05659657 0,13528856 ! endothelial cell differentiation GO:0045446 7 7 0,000 0,05659657 0,13511332 ! negative regulation of striated muscle development GO:0045843 7 7 0,000 0,05659657 0,13493853 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 7 7 0,000 0,05659657 0,13476419 ! digestive system development GO:0055123 7 7 0,000 0,05659657 0,1345903 GO:0048546|digestive tract morphogenesis, GO:0048547|gut morphogenesis, ! hemoglobin metabolic process GO:0020027 7 7 0,000 0,05659657 0,13441686 ! regulation of exit from mitosis GO:0007096 7 7 0,000 0,05659657 0,13424386 ! protein targeting to ER GO:0045047 8 7 0,000 0,05659657 0,13407131 ! cell differentiation in spinal cord GO:0021515 7 7 0,000 0,05659657 0,13389921 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 7 7 0,000 0,05659657 0,13372754 ! endoderm development GO:0007492 7 7 0,000 0,05659657 0,13355631 ! regulation of defense response to virus GO:0050688 7 7 0,000 0,05659657 0,13338553 ! glycolipid biosynthetic process GO:0009247 7 7 0,000 0,05659657 0,13321517 GO:0006688|glycosphingolipid biosynthetic process, ! response to hexose stimulus GO:0009746 7 7 0,000 0,05659657 0,13304526 GO:0034284|response to monosaccharide stimulus, GO:0009749|response to glucose stimulus, ! positive regulation of survival gene product expression GO:0045885 7 7 0,000 0,05659657 0,13287577 ! regulation of skeletal muscle fiber development GO:0048742 7 7 0,000 0,05659657 0,13270672 ! cardiac muscle tissue development GO:0048738 7 7 0,000 0,05659657 0,1325381 ! nucleotide-sugar metabolic process GO:0009225 7 7 0,000 0,05659657 0,1323699 ! complement activation, alternative pathway GO:0006957 7 7 0,000 0,05659657 0,13220213 ! arachidonic acid secretion GO:0050482 7 7 0,000 0,05659657 0,13203479 GO:0032309|icosanoid secretion, ! polyamine biosynthetic process GO:0006596 7 7 0,000 0,05659657 0,13186787 ! UV protection GO:0009650 7 7 0,000 0,05659657 0,13170137 ! DNA integration GO:0015074 7 7 0,000 0,05659657 0,13153529 ! positive regulation of carbohydrate metabolic process GO:0045913 7 7 0,000 0,05659657 0,13136962 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! positive regulation of muscle contraction GO:0045933 7 7 0,000 0,05659657 0,13120438 ! negative regulation of muscle contraction GO:0045932 7 7 0,000 0,05659657 0,13103955 ! chondroitin sulfate biosynthetic process GO:0030206 7 7 0,000 0,05659657 0,13087513 GO:0030204|chondroitin sulfate metabolic process, ! regulation of exocytosis GO:0017157 8 7 0,000 0,05659657 0,13071113 ! phosphatidylcholine biosynthetic process GO:0006656 7 7 0,000 0,05659657 0,13054754 ! heparan sulfate proteoglycan metabolic process GO:0030201 7 7 0,000 0,05659657 0,13038435 GO:0015012|heparan sulfate proteoglycan biosynthetic process, ! stem cell development GO:0048864 7 7 0,000 0,05659657 0,13022158 GO:0019827|stem cell maintenance, ! alpha-beta T cell differentiation GO:0046632 7 7 0,000 0,05659657 0,1300592 ! negative regulation of myeloid leukocyte differentiation GO:0002762 7 7 0,000 0,05659657 0,12989724 ! NLS-bearing substrate import into nucleus GO:0006607 7 7 0,000 0,05659657 0,12973567 ! eating behavior GO:0042755 7 7 0,000 0,05659657 0,12957451 ! RNA-dependent DNA replication GO:0006278 7 7 0,000 0,05659657 0,12941375 ! regulation of interleukin-8 production GO:0032677 7 7 0,000 0,05659657 0,12925339 ! ribosomal small subunit biogenesis GO:0042274 7 7 0,000 0,05659657 0,12909342 ! cranial nerve development GO:0021545 7 7 0,000 0,05659657 0,12893385 ! protein import into peroxisome matrix GO:0016558 7 7 0,000 0,05659657 0,12877467 ! induction of an organ GO:0001759 7 7 0,000 0,05659657 0,12861588 ! leukocyte activation during immune response GO:0002366 7 7 0,000 0,05659657 0,12845749 GO:0002263|cell activation during immune response, ! response to estradiol stimulus GO:0032355 7 7 0,000 0,05659657 0,12829949 ! autonomic nervous system development GO:0048483 7 7 0,000 0,05659657 0,12814187 ! intracellular lipid transport GO:0032365 7 7 0,000 0,05659657 0,12798464 ! detection of chemical stimulus GO:0009593 8 7 0,000 0,05659657 0,1278278 ! platelet activation GO:0030168 8 7 0,000 0,05659657 0,12767134 ! negative regulation of cytokine secretion GO:0050710 7 7 0,000 0,05659657 0,12751526 ! regulation of interleukin-1 secretion GO:0050704 7 7 0,000 0,05659657 0,12735956 ! natural killer cell activation GO:0030101 7 7 0,000 0,05659657 0,12720425 ! NADP metabolic process GO:0006739 7 7 0,000 0,05659657 0,12704931 ! ubiquinone metabolic process GO:0006743 7 7 0,000 0,05659657 0,12689475 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, GO:0042375|quinone cofactor metabolic process, ! regulation of macrophage differentiation GO:0045649 8 7 0,000 0,05659657 0,12674056 ! positive regulation of acute inflammatory response GO:0002675 7 7 0,000 0,05659657 0,12658675 ! regulation of osteoclast differentiation GO:0045670 7 7 0,000 0,05659657 0,12643331 ! negative regulation of cell-substrate adhesion GO:0010812 8 7 0,000 0,05659657 0,12628024 GO:0001953|negative regulation of cell-matrix adhesion, ! multicellular organismal water homeostasis GO:0050891 7 7 0,000 0,05659657 0,12612755 ! regulation of ATPase activity GO:0043462 7 7 0,000 0,05659657 0,12597522 ! cell-cell recognition GO:0009988 8 7 0,000 0,05659657 0,12582326 ! hormone catabolic process GO:0042447 7 7 0,000 0,05659657 0,12567167 ! dopamine metabolic process GO:0042417 7 7 0,000 0,05659657 0,12552044 ! cAMP biosynthetic process GO:0006171 7 7 0,000 0,05659657 0,12536957 ! oxygen transport GO:0015671 7 7 0,000 0,05659657 0,12521907 ! pyridine nucleotide biosynthetic process GO:0019363 7 7 0,000 0,05659657 0,12506892 ! regulation of mRNA stability GO:0043488 7 7 0,000 0,05659657 0,12491914 ! biogenic amine catabolic process GO:0042402 7 7 0,000 0,05659657 0,12476972 ! regulation of axon extension GO:0030516 7 7 0,000 0,05659657 0,12462065 ! cell killing GO:0001906 7 7 0,000 0,05659657 0,12447194 ! adult feeding behavior GO:0008343 7 7 0,000 0,05659657 0,12432358 ! pyrimidine nucleotide catabolic process GO:0006244 7 7 0,000 0,05659657 0,12417557 ! positive regulation of protein polymerization GO:0032273 7 7 0,000 0,05659657 0,12402792 ! response to cold GO:0009409 7 7 0,000 0,05659657 0,12388062 ! calcium ion transport GO:0006816 48 48 1,000 0,05968444 0,1304845 ! regulation of cell cycle process GO:0010564 50 48 1,000 0,05968444 0,13032989 ! protein localization in nucleus GO:0034504 48 48 1,000 0,05968444 0,13017566 ! divalent metal ion transport GO:0070838 49 49 1,000 0,06190141 0,13485141 ! skeletal muscle tissue development GO:0007519 50 49 1,000 0,06190141 0,1346922 GO:0060538|skeletal muscle organ development, ! positive regulation of cell activation GO:0050867 49 49 1,000 0,06190141 0,13453336 GO:0002696|positive regulation of leukocyte activation, ! negative regulation of transport GO:0051051 51 50 1,000 0,06414633 0,13924816 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 50 50 1,000 0,06414633 0,13908434 ! regulation of neurogenesis GO:0050767 51 50 1,000 0,06414633 0,1389209 ! anatomical structure homeostasis GO:0060249 51 50 1,000 0,06414633 0,13875785 ! regulation of skeletal muscle tissue development GO:0048641 8 8 0,000 0,06442052 0,13918759 ! negative regulation of muscle development GO:0048635 8 8 0,000 0,06442052 0,13902461 ! very-long-chain fatty acid metabolic process GO:0000038 8 8 0,000 0,06442052 0,13886201 ! positive regulation of translation GO:0045727 8 8 0,000 0,06442052 0,13869979 ! superoxide anion generation GO:0042554 8 8 0,000 0,06442052 0,13853794 ! sulfur amino acid biosynthetic process GO:0000097 8 8 0,000 0,06442052 0,13837648 ! cGMP metabolic process GO:0046068 8 8 0,000 0,06442052 0,13821539 GO:0006182|cGMP biosynthetic process, ! thyroid gland development GO:0030878 8 8 0,000 0,06442052 0,13805467 ! 'de novo' protein folding GO:0006458 8 8 0,000 0,06442052 0,13789433 ! dicarboxylic acid transport GO:0006835 8 8 0,000 0,06442052 0,13773436 ! phosphoinositide phosphorylation GO:0046854 8 8 0,000 0,06442052 0,13757476 ! negative regulation of bone remodeling GO:0046851 8 8 0,000 0,06442052 0,13741553 ! embryonic hindlimb morphogenesis GO:0035116 8 8 0,000 0,06442052 0,13725667 ! zinc ion transport GO:0006829 8 8 0,000 0,06442052 0,13709817 ! embryonic forelimb morphogenesis GO:0035115 8 8 0,000 0,06442052 0,13694004 ! folic acid and derivative biosynthetic process GO:0009396 8 8 0,000 0,06442052 0,13678228 ! regulation of neuronal synaptic plasticity GO:0048168 8 8 0,000 0,06442052 0,13662488 ! cardiac muscle contraction GO:0060048 8 8 0,000 0,06442052 0,13646784 ! lipid localization GO:0010876 8 8 0,000 0,06442052 0,13631116 GO:0019915|lipid storage, ! response to pain GO:0048265 8 8 0,000 0,06442052 0,13615484 ! response to cAMP GO:0051591 8 8 0,000 0,06442052 0,13599888 ! COPI coating of Golgi vesicle GO:0048205 8 8 0,000 0,06442052 0,13584327 GO:0048200|Golgi transport vesicle coating, ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 8 0,000 0,06442052 0,13568802 ! negative regulation of transcription factor import into nucleus GO:0042992 8 8 0,000 0,06442052 0,13553313 ! negative regulation of ion transport GO:0043271 8 8 0,000 0,06442052 0,13537858 ! regulation of response to extracellular stimulus GO:0032104 8 8 0,000 0,06442052 0,13522439 GO:0032107|regulation of response to nutrient levels, ! adult walking behavior GO:0007628 8 8 0,000 0,06442052 0,13507056 ! sensory perception of taste GO:0050909 8 8 0,000 0,06442052 0,13491707 ! pancreas development GO:0031016 8 8 0,000 0,06442052 0,13476393 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 8 8 0,000 0,06442052 0,13461113 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 8 8 0,000 0,06442052 0,13445868 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 8 8 0,000 0,06442052 0,13430658 ! sperm motility GO:0030317 8 8 0,000 0,06442052 0,13415482 ! regulation of striated muscle contraction GO:0006942 8 8 0,000 0,06442052 0,13400341 ! DNA duplex unwinding GO:0032508 8 8 0,000 0,06442052 0,13385233 GO:0032392|DNA geometric change, ! glycine metabolic process GO:0006544 8 8 0,000 0,06442052 0,1337016 ! negative regulation of microtubule depolymerization GO:0007026 8 8 0,000 0,06442052 0,1335512 GO:0031114|regulation of microtubule depolymerization, ! polyamine metabolic process GO:0006595 8 8 0,000 0,06442052 0,13340114 ! Golgi organization GO:0007030 8 8 0,000 0,06442052 0,13325142 ! cell-cell junction assembly GO:0007043 8 8 0,000 0,06442052 0,13310204 ! regulation of stress fiber formation GO:0051492 9 8 0,000 0,06442052 0,13295299 ! positive regulation of endothelial cell migration GO:0010595 8 8 0,000 0,06442052 0,13280427 ! fructose metabolic process GO:0006000 8 8 0,000 0,06442052 0,13265589 ! mannose metabolic process GO:0006013 9 8 0,000 0,06442052 0,13250783 ! NAD metabolic process GO:0019674 8 8 0,000 0,06442052 0,13236011 ! sex determination GO:0007530 8 8 0,000 0,06442052 0,13221272 ! negative regulation of mitotic cell cycle GO:0045930 9 8 0,000 0,06442052 0,13206565 ! plasma membrane fusion GO:0045026 8 8 0,000 0,06442052 0,13191891 ! response to fungus GO:0009620 8 8 0,000 0,06442052 0,1317725 ! stem cell differentiation GO:0048863 8 8 0,000 0,06442052 0,13162641 ! alpha-beta T cell activation GO:0046631 8 8 0,000 0,06442052 0,13148064 ! positive regulation of myeloid leukocyte differentiation GO:0002763 9 8 0,000 0,06442052 0,1313352 ! embryonic digit morphogenesis GO:0042733 8 8 0,000 0,06442052 0,13119008 ! regulation of cytokine production during immune response GO:0002718 8 8 0,000 0,06442052 0,13104527 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 0,06442052 0,13090079 ! regulation of vasodilation GO:0042312 8 8 0,000 0,06442052 0,13075663 ! vasoconstriction GO:0042310 8 8 0,000 0,06442052 0,13061278 ! regulation of fatty acid metabolic process GO:0019217 8 8 0,000 0,06442052 0,13046925 ! sensory perception of pain GO:0019233 8 8 0,000 0,06442052 0,13032604 ! gastrulation with mouth forming second GO:0001702 8 8 0,000 0,06442052 0,13018313 ! immunoglobulin production during immune response GO:0002381 8 8 0,000 0,06442052 0,13004055 GO:0002208|somatic diversification of immunoglobulins during immune response, GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! mRNA cleavage GO:0006379 8 8 0,000 0,06442052 0,12989827 ! chromatin silencing GO:0006342 8 8 0,000 0,06442052 0,1297563 ! tissue regeneration GO:0042246 8 8 0,000 0,06442052 0,12961465 ! salivary gland development GO:0007431 8 8 0,000 0,06442052 0,1294733 ! negative regulation of blood coagulation GO:0030195 9 8 0,000 0,06442052 0,12933226 ! T cell homeostasis GO:0043029 8 8 0,000 0,06442052 0,12919153 ! peptide biosynthetic process GO:0043043 9 8 0,000 0,06442052 0,12905111 ! peptidyl-serine modification GO:0018209 8 8 0,000 0,06442052 0,12891099 ! water homeostasis GO:0030104 8 8 0,000 0,06442052 0,12877117 ! cofactor transport GO:0051181 8 8 0,000 0,06442052 0,12863166 ! regulation of acute inflammatory response GO:0002673 8 8 0,000 0,06442052 0,12849244 ! acid secretion GO:0046717 8 8 0,000 0,06442052 0,12835353 ! positive regulation of leukocyte migration GO:0002687 8 8 0,000 0,06442052 0,12821492 ! C21-steroid hormone biosynthetic process GO:0006700 8 8 0,000 0,06442052 0,12807661 ! protein-chromophore linkage GO:0018298 9 8 0,000 0,06442052 0,1279386 ! catecholamine biosynthetic process GO:0042423 8 8 0,000 0,06442052 0,12780088 ! regulation of RNA stability GO:0043487 8 8 0,000 0,06442052 0,12766346 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 8 8 0,000 0,06442052 0,12752634 ! regulation of generation of precursor metabolites and energy GO:0043467 8 8 0,000 0,06442052 0,1273895 ! aromatic compound biosynthetic process GO:0019438 8 8 0,000 0,06442052 0,12725297 ! regulation of organic acid transport GO:0032890 8 8 0,000 0,06442052 0,12711672 ! positive regulation of calcium ion transport GO:0051928 8 8 0,000 0,06442052 0,12698077 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 8 8 0,000 0,06442052 0,12684511 ! regulation of multi-organism process GO:0043900 8 8 0,000 0,06442052 0,12670973 ! positive regulation of amine transport GO:0051954 8 8 0,000 0,06442052 0,12657465 ! developmental induction GO:0031128 8 8 0,000 0,06442052 0,12643985 GO:0045168|cell-cell signaling involved in cell fate specification, ! peptide hormone secretion GO:0030072 8 8 0,000 0,06442052 0,12630534 ! positive regulation of calcium-mediated signaling GO:0050850 8 8 0,000 0,06442052 0,12617111 ! cytoplasmic sequestering of protein GO:0051220 8 8 0,000 0,06442052 0,12603717 ! peptide hormone processing GO:0016486 8 8 0,000 0,06442052 0,12590352 ! positive regulation of synaptic transmission GO:0050806 8 8 0,000 0,06442052 0,12577015 ! regulation of steroid biosynthetic process GO:0050810 8 8 0,000 0,06442052 0,12563706 ! positive regulation of immune response GO:0050778 51 51 1,000 0,06641862 0,12939696 ! ATP biosynthetic process GO:0006754 51 51 1,000 0,06641862 0,12926032 ! protein maturation GO:0051604 51 51 1,000 0,06641862 0,12912397 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 52 52 1,000 0,0687177 0,13345281 ! cell fate commitment GO:0045165 52 52 1,000 0,0687177 0,13331233 ! regulation of GTPase activity GO:0043087 53 52 1,000 0,0687177 0,13317215 ! regulation of protein transport GO:0051223 53 53 1,000 0,07104297 0,13753381 GO:0070201|regulation of establishment of protein localization, ! lactation GO:0007595 10 9 0,000 0,07218071 0,13958977 ! embryonic pattern specification GO:0009880 10 9 0,000 0,07218071 0,13944345 ! positive regulation of cell projection organization GO:0031346 9 9 0,000 0,07218071 0,13929743 ! positive regulation of protein complex assembly GO:0031334 9 9 0,000 0,07218071 0,13915173 ! cortical actin cytoskeleton organization GO:0030866 10 9 0,000 0,07218071 0,13900632 ! negative regulation of cell cycle process GO:0010948 9 9 0,000 0,07218071 0,13886122 ! regulation of nitric-oxide synthase activity GO:0050999 9 9 0,000 0,07218071 0,13871642 ! viral genome replication GO:0019079 9 9 0,000 0,07218071 0,13857193 ! phospholipid catabolic process GO:0009395 9 9 0,000 0,07218071 0,13842773 ! copper ion transport GO:0006825 9 9 0,000 0,07218071 0,13828384 ! lipid phosphorylation GO:0046834 9 9 0,000 0,07218071 0,13814024 ! aminoglycan catabolic process GO:0006026 9 9 0,000 0,07218071 0,13799694 ! Golgi vesicle budding GO:0048194 9 9 0,000 0,07218071 0,13785394 ! regulation of cell-cell adhesion GO:0022407 9 9 0,000 0,07218071 0,13771123 ! RNA polyadenylation GO:0043631 9 9 0,000 0,07218071 0,13756882 GO:0006378|mRNA polyadenylation, ! gamma-aminobutyric acid signaling pathway GO:0007214 9 9 0,000 0,07218071 0,1374267 ! regulation of postsynaptic membrane potential GO:0060078 9 9 0,000 0,07218071 0,13728488 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 9 9 0,000 0,07218071 0,13714335 ! negative regulation of cytokine biosynthetic process GO:0042036 9 9 0,000 0,07218071 0,13700211 ! phospholipid efflux GO:0033700 9 9 0,000 0,07218071 0,13686116 ! response to alkaloid GO:0043279 10 9 0,000 0,07218071 0,1367205 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 9 9 0,000 0,07218071 0,13658013 ! cytokine biosynthetic process GO:0042089 9 9 0,000 0,07218071 0,13644005 GO:0042107|cytokine metabolic process, ! positive regulation of endothelial cell proliferation GO:0001938 9 9 0,000 0,07218071 0,13630026 ! negative regulation of gene expression, epigenetic GO:0045814 9 9 0,000 0,07218071 0,13616075 ! regulation of interleukin-2 biosynthetic process GO:0045076 9 9 0,000 0,07218071 0,13602152 ! response to ethanol GO:0045471 9 9 0,000 0,07218071 0,13588258 ! platelet-derived growth factor receptor signaling pathway GO:0048008 9 9 0,000 0,07218071 0,13574393 ! pyrimidine ribonucleotide metabolic process GO:0009218 9 9 0,000 0,07218071 0,13560556 ! activation of pro-apoptotic gene products GO:0008633 9 9 0,000 0,07218071 0,13546746 ! methionine metabolic process GO:0006555 9 9 0,000 0,07218071 0,13532965 ! glutamine metabolic process GO:0006541 9 9 0,000 0,07218071 0,13519212 ! cerebral cortex development GO:0021987 9 9 0,000 0,07218071 0,13505487 ! response to osmotic stress GO:0006970 9 9 0,000 0,07218071 0,1349179 ! pigmentation during development GO:0048066 9 9 0,000 0,07218071 0,13478121 ! reverse cholesterol transport GO:0043691 9 9 0,000 0,07218071 0,13464479 ! central nervous system neuron development GO:0021954 10 9 0,000 0,07218071 0,13450864 ! pyrimidine ribonucleoside metabolic process GO:0046131 9 9 0,000 0,07218071 0,13437278 ! nucleobase biosynthetic process GO:0046112 9 9 0,000 0,07218071 0,13423718 ! substrate-bound cell migration GO:0006929 9 9 0,000 0,07218071 0,13410186 ! neurotransmitter metabolic process GO:0042133 11 9 0,000 0,07218071 0,13396682 ! branching involved in ureteric bud morphogenesis GO:0001658 9 9 0,000 0,07218071 0,13383204 GO:0060675|ureteric bud morphogenesis, ! L-glutamate transport GO:0015813 9 9 0,000 0,07218071 0,13369754 GO:0015800|acidic amino acid transport, ! peptide secretion GO:0002790 9 9 0,000 0,07218071 0,1335633 ! regulation of dephosphorylation GO:0035303 9 9 0,000 0,07218071 0,13342934 ! cotranslational protein targeting to membrane GO:0006613 10 9 0,000 0,07218071 0,13329564 ! positive regulation of alpha-beta T cell differentiation GO:0046638 9 9 0,000 0,07218071 0,13316221 ! ventricular cardiac muscle morphogenesis GO:0055010 9 9 0,000 0,07218071 0,13302905 ! behavioral interaction between organisms GO:0051705 9 9 0,000 0,07218071 0,13289615 ! negative regulation of protein import into nucleus GO:0042308 9 9 0,000 0,07218071 0,13276352 ! positive regulation of protein import into nucleus GO:0042307 9 9 0,000 0,07218071 0,13263116 ! DNA replication initiation GO:0006270 9 9 0,000 0,07218071 0,13249905 ! prostaglandin metabolic process GO:0006693 9 9 0,000 0,07218071 0,13236721 GO:0006692|prostanoid metabolic process, ! histone acetylation GO:0016573 9 9 0,000 0,07218071 0,13223564 ! DNA fragmentation involved in apoptosis GO:0006309 9 9 0,000 0,07218071 0,13210432 ! cellular amino acid derivative catabolic process GO:0042219 10 9 0,000 0,07218071 0,13197326 ! positive regulation of oxidoreductase activity GO:0051353 9 9 0,000 0,07218071 0,13184247 ! positive regulation of cytokine secretion GO:0050715 9 9 0,000 0,07218071 0,13171193 ! negative regulation of inflammatory response GO:0050728 9 9 0,000 0,07218071 0,13158165 ! negative regulation of tissue remodeling GO:0034104 9 9 0,000 0,07218071 0,13145163 ! negative regulation of protein secretion GO:0050709 9 9 0,000 0,07218071 0,13132187 ! regulation of leukocyte migration GO:0002685 9 9 0,000 0,07218071 0,13119236 ! positive regulation of transmission of nerve impulse GO:0051971 9 9 0,000 0,07218071 0,1310631 ! collagen catabolic process GO:0030574 9 9 0,000 0,07218071 0,1309341 ! aromatic amino acid family catabolic process GO:0009074 9 9 0,000 0,07218071 0,13080536 ! purine base metabolic process GO:0006144 9 9 0,000 0,07218071 0,13067687 ! gas transport GO:0015669 9 9 0,000 0,07218071 0,13054863 ! cholesterol efflux GO:0033344 9 9 0,000 0,07218071 0,13042064 ! estrogen receptor signaling pathway GO:0030520 9 9 0,000 0,07218071 0,1302929 ! somatic recombination of immunoglobulin gene segments GO:0016447 9 9 0,000 0,07218071 0,13016541 ! regulation of actin filament bundle formation GO:0032231 10 9 0,000 0,07218071 0,13003817 ! regulation of blood vessel endothelial cell migration GO:0043535 9 9 0,000 0,07218071 0,12991118 ! regulation of calcium-mediated signaling GO:0050848 9 9 0,000 0,07218071 0,12978444 ! actin filament-based movement GO:0030048 9 9 0,000 0,07218071 0,12965794 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 9 9 0,000 0,07218071 0,12953169 ! response to virus GO:0009615 54 54 1,000 0,07339386 0,13158063 ! sulfur metabolic process GO:0006790 55 54 1,000 0,07339386 0,13145276 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 55 55 1,000 0,07576981 0,13557647 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! microtubule cytoskeleton organization GO:0000226 55 55 1,000 0,07576981 0,13544497 ! in utero embryonic development GO:0001701 55 55 1,000 0,07576981 0,13531373 ! ribonucleoside triphosphate biosynthetic process GO:0009201 56 56 1,000 0,07817026 0,13946543 ! regulation of nervous system development GO:0051960 57 56 1,000 0,07817026 0,13933055 ! protein import into nucleus, docking GO:0000059 10 10 0,000 0,07987765 0,14223625 ! regulation of protein ubiquitination GO:0031396 10 10 0,000 0,07987765 0,14209895 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 10 10 0,000 0,07987765 0,14196193 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 10 10 0,000 0,07987765 0,14182516 ! regulation of glucose metabolic process GO:0010906 10 10 0,000 0,07987765 0,14168866 ! ER-associated protein catabolic process GO:0030433 10 10 0,000 0,07987765 0,14155242 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! neuron maturation GO:0042551 10 10 0,000 0,07987765 0,14141644 ! pteridine and derivative metabolic process GO:0042558 10 10 0,000 0,07987765 0,14128073 ! positive regulation of anti-apoptosis GO:0045768 10 10 0,000 0,07987765 0,14114527 GO:0045767|regulation of anti-apoptosis, ! cortical cytoskeleton organization GO:0030865 11 10 0,000 0,07987765 0,14101007 ! regulation of lipid biosynthetic process GO:0046890 10 10 0,000 0,07987765 0,14087514 ! reciprocal meiotic recombination GO:0007131 10 10 0,000 0,07987765 0,14074046 ! hormone secretion GO:0046879 10 10 0,000 0,07987765 0,14060603 ! glucosamine metabolic process GO:0006041 10 10 0,000 0,07987765 0,14047187 GO:0006044|N-acetylglucosamine metabolic process, ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 10 10 0,000 0,07987765 0,14033796 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! inositol metabolic process GO:0006020 10 10 0,000 0,07987765 0,1402043 ! cAMP metabolic process GO:0046058 10 10 0,000 0,07987765 0,1400709 ! vesicle targeting, to, from or within Golgi GO:0048199 10 10 0,000 0,07987765 0,13993775 ! transcription from RNA polymerase III promoter GO:0006383 10 10 0,000 0,07987765 0,13980486 ! forelimb morphogenesis GO:0035136 10 10 0,000 0,07987765 0,13967222 ! glial cell development GO:0021782 10 10 0,000 0,07987765 0,13953983 ! calcium-independent cell-cell adhesion GO:0016338 10 10 0,000 0,07987765 0,13940769 ! auditory receptor cell differentiation GO:0042491 10 10 0,000 0,07987765 0,1392758 ! fat cell differentiation GO:0045444 10 10 0,000 0,07987765 0,13914416 ! myoblast differentiation GO:0045445 10 10 0,000 0,07987765 0,13901276 ! inactivation of MAPK activity GO:0000188 10 10 0,000 0,07987765 0,13888162 ! positive regulation of proteolysis GO:0045862 10 10 0,000 0,07987765 0,13875072 ! response to carbohydrate stimulus GO:0009743 10 10 0,000 0,07987765 0,13862007 ! regulation of survival gene product expression GO:0045884 10 10 0,000 0,07987765 0,13848967 ! induction of apoptosis via death domain receptors GO:0008625 10 10 0,000 0,07987765 0,13835951 ! epidermis morphogenesis GO:0048730 10 10 0,000 0,07987765 0,13822959 ! protein polyubiquitination GO:0000209 10 10 0,000 0,07987765 0,13809992 ! glutamate metabolic process GO:0006536 11 10 0,000 0,07987765 0,13797049 ! plasma membrane organization GO:0007009 10 10 0,000 0,07987765 0,13784131 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 10 10 0,000 0,07987765 0,13771236 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cell-substrate junction assembly GO:0007044 11 10 0,000 0,07987765 0,13758366 ! lysosomal transport GO:0007041 10 10 0,000 0,07987765 0,1374552 ! cellular response to unfolded protein GO:0034620 10 10 0,000 0,07987765 0,13732697 GO:0030968|endoplasmic reticulum unfolded protein response, ! central nervous system neuron differentiation GO:0021953 11 10 0,000 0,07987765 0,13719899 ! vesicle coating GO:0006901 10 10 0,000 0,07987765 0,13707124 ! exocrine system development GO:0035272 10 10 0,000 0,07987765 0,13694374 ! cell structure disassembly during apoptosis GO:0006921 10 10 0,000 0,07987765 0,13681647 ! embryo implantation GO:0007566 11 10 0,000 0,07987765 0,13668943 ! regulation of protein binding GO:0043393 11 10 0,000 0,07987765 0,13656263 ! protein targeting to peroxisome GO:0006625 10 10 0,000 0,07987765 0,13643607 ! protein targeting to mitochondrion GO:0006626 10 10 0,000 0,07987765 0,13630974 GO:0070585|protein localization in mitochondrion, ! regulation of alpha-beta T cell differentiation GO:0046637 10 10 0,000 0,07987765 0,13618364 ! intermediate filament cytoskeleton organization GO:0045104 10 10 0,000 0,07987765 0,13605778 ! protein export from nucleus GO:0006611 10 10 0,000 0,07987765 0,13593215 ! cytolysis GO:0019835 10 10 0,000 0,07987765 0,13580675 ! positive regulation of biomineral formation GO:0070169 10 10 0,000 0,07987765 0,13568158 GO:0030501|positive regulation of bone mineralization, ! mismatch repair GO:0006298 10 10 0,000 0,07987765 0,13555665 ! histone deacetylation GO:0016575 10 10 0,000 0,07987765 0,13543194 ! mRNA splice site selection GO:0006376 11 10 0,000 0,07987765 0,13530746 ! synaptic vesicle transport GO:0048489 11 10 0,000 0,07987765 0,13518321 ! gland morphogenesis GO:0022612 10 10 0,000 0,07987765 0,13505919 ! positive regulation of neurological system process GO:0031646 10 10 0,000 0,07987765 0,1349354 ! sphingolipid biosynthetic process GO:0030148 10 10 0,000 0,07987765 0,13481183 GO:0046467|membrane lipid biosynthetic process, ! sphingolipid catabolic process GO:0030149 10 10 0,000 0,07987765 0,13468849 GO:0046466|membrane lipid catabolic process, ! nerve-nerve synaptic transmission GO:0007270 10 10 0,000 0,07987765 0,13456537 ! regulation of erythrocyte differentiation GO:0045646 10 10 0,000 0,07987765 0,13444248 ! regulation of epidermis development GO:0045682 10 10 0,000 0,07987765 0,13431981 ! folic acid and derivative metabolic process GO:0006760 10 10 0,000 0,07987765 0,13419737 ! negative regulation of neuron differentiation GO:0045665 10 10 0,000 0,07987765 0,13407515 ! aspartate family amino acid biosynthetic process GO:0009067 10 10 0,000 0,07987765 0,13395315 ! regulation of BMP signaling pathway GO:0030510 10 10 0,000 0,07987765 0,13383138 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 10 10 0,000 0,07987765 0,13370982 ! lymphocyte homeostasis GO:0002260 10 10 0,000 0,07987765 0,13358849 ! nerve development GO:0021675 10 10 0,000 0,07987765 0,13346738 ! epithelial to mesenchymal transition GO:0001837 10 10 0,000 0,07987765 0,13334648 ! gut development GO:0048565 10 10 0,000 0,07987765 0,13322581 ! embryonic organ morphogenesis GO:0048562 10 10 0,000 0,07987765 0,13310535 ! negative regulation of homeostatic process GO:0032845 10 10 0,000 0,07987765 0,13298511 ! mRNA 3'-end processing GO:0031124 10 10 0,000 0,07987765 0,13286509 ! negative regulation of coagulation GO:0050819 11 10 0,000 0,07987765 0,13274528 ! protein stabilization GO:0050821 10 10 0,000 0,07987765 0,13262569 ! nucleoside triphosphate biosynthetic process GO:0009142 57 57 1,000 0,08059466 0,13369573 ! regulation of protein localization GO:0032880 58 57 1,000 0,08059466 0,1335755 ! peptidyl-amino acid modification GO:0018193 61 59 1,000 0,08551311 0,14159988 ! regulation of cell development GO:0060284 60 59 1,000 0,08551311 0,14147277 ! protein localization in organelle GO:0033365 59 59 1,000 0,08551311 0,14134589 ! immune effector process GO:0002252 59 59 1,000 0,08551311 0,14121923 ! protein secretion GO:0009306 11 11 0,000 0,08751186 0,14439065 ! oligosaccharide metabolic process GO:0009311 11 11 0,000 0,08751186 0,1442615 ! myeloid leukocyte differentiation GO:0002573 12 11 0,000 0,08751186 0,14413258 ! negative regulation of defense response GO:0031348 11 11 0,000 0,08751186 0,14400389 ! G1 phase of mitotic cell cycle GO:0000080 12 11 0,000 0,08751186 0,14387543 ! determination of bilateral symmetry GO:0009855 11 11 0,000 0,08751186 0,14374719 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! positive regulation of hormone secretion GO:0046887 11 11 0,000 0,08751186 0,14361919 ! phosphatidylinositol metabolic process GO:0046488 11 11 0,000 0,08751186 0,14349142 ! signal complex assembly GO:0007172 11 11 0,000 0,08751186 0,14336387 ! endothelial cell migration GO:0043542 11 11 0,000 0,08751186 0,14323655 ! peroxisomal transport GO:0043574 11 11 0,000 0,08751186 0,14310945 ! protein amino acid methylation GO:0006479 11 11 0,000 0,08751186 0,14298258 GO:0008213|protein amino acid alkylation, ! protein amino acid acetylation GO:0006473 11 11 0,000 0,08751186 0,14285594 ! positive regulation of nucleocytoplasmic transport GO:0046824 11 11 0,000 0,08751186 0,14272952 GO:0032388|positive regulation of intracellular transport, ! heart contraction GO:0060047 11 11 0,000 0,08751186 0,14260332 GO:0003015|heart process, ! dendrite development GO:0016358 11 11 0,000 0,08751186 0,14247734 ! regulation of transmembrane transporter activity GO:0022898 11 11 0,000 0,08751186 0,14235159 GO:0032412|regulation of ion transmembrane transporter activity, GO:0032409|regulation of transporter activity, ! negative regulation of endothelial cell proliferation GO:0001937 11 11 0,000 0,08751186 0,14222606 ! regulation of viral genome replication GO:0045069 11 11 0,000 0,08751186 0,14210075 ! spinal cord development GO:0021510 11 11 0,000 0,08751186 0,14197566 ! smooth muscle contraction GO:0006939 11 11 0,000 0,08751186 0,14185079 ! positive regulation of nitric oxide biosynthetic process GO:0045429 11 11 0,000 0,08751186 0,14172614 ! cellular macromolecular complex disassembly GO:0034623 12 11 0,000 0,08751186 0,14160171 ! digestive system process GO:0022600 11 11 0,000 0,08751186 0,1414775 ! mitotic spindle organization GO:0007052 11 11 0,000 0,08751186 0,14135351 ! fucose metabolic process GO:0006004 11 11 0,000 0,08751186 0,14122973 ! membrane budding GO:0006900 11 11 0,000 0,08751186 0,14110617 ! apoptotic nuclear changes GO:0030262 11 11 0,000 0,08751186 0,14098283 ! monoamine transport GO:0015844 11 11 0,000 0,08751186 0,1408597 ! regulation of cellular ketone metabolic process GO:0010565 11 11 0,000 0,08751186 0,14073678 ! response to lipopolysaccharide GO:0032496 11 11 0,000 0,08751186 0,14061408 ! body fluid secretion GO:0007589 11 11 0,000 0,08751186 0,1404916 ! cardiac muscle tissue morphogenesis GO:0055008 11 11 0,000 0,08751186 0,14036932 GO:0060415|muscle tissue morphogenesis, ! interaction with host GO:0051701 11 11 0,000 0,08751186 0,14024726 ! membrane depolarization GO:0051899 11 11 0,000 0,08751186 0,14012542 ! regulation of interleukin-2 production GO:0032663 11 11 0,000 0,08751186 0,14000378 ! regulation of ARF GTPase activity GO:0032312 11 11 0,000 0,08751186 0,13988235 ! regulation of monooxygenase activity GO:0032768 11 11 0,000 0,08751186 0,13976114 ! oogenesis GO:0048477 11 11 0,000 0,08751186 0,13964013 ! negative regulation of angiogenesis GO:0016525 11 11 0,000 0,08751186 0,13951934 ! regulation of cellular carbohydrate metabolic process GO:0010675 11 11 0,000 0,08751186 0,13939875 GO:0006109|regulation of carbohydrate metabolic process, ! vitamin transport GO:0051180 11 11 0,000 0,08751186 0,13927837 ! muscle maintenance GO:0046716 12 11 0,000 0,08751186 0,1391582 ! vitamin A metabolic process GO:0006776 11 11 0,000 0,08751186 0,13903824 ! hindbrain development GO:0030902 11 11 0,000 0,08751186 0,13891848 ! steroid catabolic process GO:0006706 11 11 0,000 0,08751186 0,13879893 ! endocrine process GO:0050886 11 11 0,000 0,08751186 0,13867958 GO:0001990|regulation of systemic arterial blood pressure by hormone, ! aromatic amino acid family metabolic process GO:0009072 11 11 0,000 0,08751186 0,13856044 ! proximal/distal pattern formation GO:0009954 11 11 0,000 0,08751186 0,1384415 ! somatic diversification of immunoglobulins GO:0016445 11 11 0,000 0,08751186 0,13832277 ! RNA 3'-end processing GO:0031123 11 11 0,000 0,08751186 0,13820424 ! protein polymerization GO:0051258 65 60 1,000 0,0880061 0,13886579 ! morphogenesis of an epithelium GO:0002009 63 62 1,000 0,09305699 0,14671004 GO:0060429|epithelium development, ! protein import GO:0017038 62 62 1,000 0,09305699 0,14658464 ! di-, tri-valent inorganic cation transport GO:0015674 63 62 1,000 0,09305699 0,14645947 ! translational initiation GO:0006413 12 12 0,000 0,09508382 0,14952174 ! positive regulation of angiogenesis GO:0045766 12 12 0,000 0,09508382 0,14939427 ! initiation of viral infection GO:0019059 12 12 0,000 0,09508382 0,14926702 ! DNA catabolic process, endonucleolytic GO:0000737 12 12 0,000 0,09508382 0,14913999 ! iron ion transport GO:0006826 13 12 0,000 0,09508382 0,14901317 ! phosphatidylcholine metabolic process GO:0046470 12 12 0,000 0,09508382 0,14888656 ! amino sugar metabolic process GO:0006040 12 12 0,000 0,09508382 0,14876017 ! post-Golgi vesicle-mediated transport GO:0006892 12 12 0,000 0,09508382 0,148634 ! protein amino acid ADP-ribosylation GO:0006471 12 12 0,000 0,09508382 0,14850804 ! collagen metabolic process GO:0032963 12 12 0,000 0,09508382 0,14838229 ! hindlimb morphogenesis GO:0035137 12 12 0,000 0,09508382 0,14825675 ! glutamate signaling pathway GO:0007215 12 12 0,000 0,09508382 0,14813143 ! C21-steroid hormone metabolic process GO:0008207 13 12 0,000 0,09508382 0,14800632 ! regulation of muscle cell differentiation GO:0051147 13 12 0,000 0,09508382 0,14788142 ! cellular response to hydrogen peroxide GO:0070301 12 12 0,000 0,09508382 0,14775673 GO:0042744|hydrogen peroxide catabolic process, ! positive regulation of endocytosis GO:0045807 12 12 0,000 0,09508382 0,14763225 ! retinoid metabolic process GO:0001523 12 12 0,000 0,09508382 0,14750798 GO:0016101|diterpenoid metabolic process, ! mitotic chromosome condensation GO:0007076 12 12 0,000 0,09508382 0,14738392 ! positive regulation of innate immune response GO:0045089 12 12 0,000 0,09508382 0,14726007 ! GPI anchor biosynthetic process GO:0006506 12 12 0,000 0,09508382 0,14713643 GO:0006505|GPI anchor metabolic process, ! acute-phase response GO:0006953 12 12 0,000 0,09508382 0,14701299 ! deoxyribonucleotide catabolic process GO:0009264 12 12 0,000 0,09508382 0,14688976 ! vacuolar transport GO:0007034 12 12 0,000 0,09508382 0,14676674 ! polysaccharide catabolic process GO:0000272 12 12 0,000 0,09508382 0,14664392 ! vesicle docking during exocytosis GO:0006904 12 12 0,000 0,09508382 0,14652131 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 12 12 0,000 0,09508382 0,1463989 ! barbed-end actin filament capping GO:0051016 12 12 0,000 0,09508382 0,1462767 GO:0051693|actin filament capping, ! osteoblast differentiation GO:0001649 12 12 0,000 0,09508382 0,1461547 ! male gonad development GO:0008584 12 12 0,000 0,09508382 0,1460329 ! regulation of insulin secretion GO:0050796 12 12 0,000 0,09508382 0,14591131 ! renal system process GO:0003014 12 12 0,000 0,09508382 0,14578992 ! regulation of tumor necrosis factor production GO:0032680 12 12 0,000 0,09508382 0,14566873 ! regulation of steroid metabolic process GO:0019218 12 12 0,000 0,09508382 0,14554774 ! fibroblast growth factor receptor signaling pathway GO:0008543 12 12 0,000 0,09508382 0,14542696 ! regulation of interleukin-6 production GO:0032675 12 12 0,000 0,09508382 0,14530637 ! pallium development GO:0021543 13 12 0,000 0,09508382 0,14518598 ! cell fate determination GO:0001709 12 12 0,000 0,09508382 0,1450658 ! regulation of chromosome organization GO:0033044 12 12 0,000 0,09508382 0,14494581 ! somitogenesis GO:0001756 13 12 0,000 0,09508382 0,14482602 ! G1 phase GO:0051318 13 12 0,000 0,09508382 0,14470643 ! regulation of response to biotic stimulus GO:0002831 12 12 0,000 0,09508382 0,14458703 ! fat-soluble vitamin metabolic process GO:0006775 12 12 0,000 0,09508382 0,14446783 ! hormone transport GO:0009914 12 12 0,000 0,09508382 0,14434883 ! neurotransmitter secretion GO:0007269 14 12 0,000 0,09508382 0,14423003 ! heme biosynthetic process GO:0006783 12 12 0,000 0,09508382 0,14411142 ! spermatid differentiation GO:0048515 13 12 0,000 0,09508382 0,143993 GO:0007286|spermatid development, ! aromatic compound catabolic process GO:0019439 13 12 0,000 0,09508382 0,14387478 ! pyrimidine nucleotide biosynthetic process GO:0006221 12 12 0,000 0,09508382 0,14375675 ! neural tube closure GO:0001843 13 12 0,000 0,09508382 0,14363892 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! regulation of mitotic metaphase/anaphase transition GO:0030071 13 12 0,000 0,09508382 0,14352128 ! negative regulation of translation GO:0017148 12 12 0,000 0,09508382 0,14340383 ! regulation of microtubule polymerization or depolymerization GO:0031110 12 12 0,000 0,09508382 0,14328658 ! positive regulation of cellular component organization GO:0051130 65 65 1,000 0,10078795 0,15175832 ! positive regulation of DNA replication GO:0045740 14 13 0,000 0,10259405 0,1543517 ! positive regulation of smooth muscle cell proliferation GO:0048661 13 13 0,000 0,10259405 0,1542258 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 13 13 0,000 0,10259405 0,1541001 GO:0016444|somatic cell DNA recombination, ! negative regulation of actin filament polymerization GO:0030837 13 13 0,000 0,10259405 0,15397461 ! phenol metabolic process GO:0018958 13 13 0,000 0,10259405 0,15384933 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, GO:0009712|catechol metabolic process, ! gluconeogenesis GO:0006094 13 13 0,000 0,10259405 0,15372425 ! negative regulation of hormone secretion GO:0046888 13 13 0,000 0,10259405 0,15359937 ! 2'-deoxyribonucleotide metabolic process GO:0009394 13 13 0,000 0,10259405 0,1534747 GO:0019692|deoxyribose phosphate metabolic process, ! glycosaminoglycan biosynthetic process GO:0006024 13 13 0,000 0,10259405 0,15335022 ! regeneration GO:0031099 13 13 0,000 0,10259405 0,15322595 ! keratinization GO:0031424 13 13 0,000 0,10259405 0,15310188 ! post-embryonic development GO:0009791 14 13 0,000 0,10259405 0,15297802 ! patterning of blood vessels GO:0001569 13 13 0,000 0,10259405 0,15285435 ! vasculogenesis GO:0001570 13 13 0,000 0,10259405 0,15273088 ! regulation of innate immune response GO:0045088 13 13 0,000 0,10259405 0,15260761 ! regulation of nitric oxide biosynthetic process GO:0045428 13 13 0,000 0,10259405 0,15248454 ! multicellular organismal macromolecule metabolic process GO:0044259 13 13 0,000 0,10259405 0,15236167 ! response to corticosteroid stimulus GO:0031960 13 13 0,000 0,10259405 0,15223899 GO:0051384|response to glucocorticoid stimulus, ! multicellular organismal catabolic process GO:0044243 13 13 0,000 0,10259405 0,15211651 ! autophagy GO:0006914 13 13 0,000 0,10259405 0,15199423 ! receptor metabolic process GO:0043112 14 13 0,000 0,10259405 0,15187215 ! actin filament bundle formation GO:0051017 13 13 0,000 0,10259405 0,15175026 ! ureteric bud development GO:0001657 13 13 0,000 0,10259405 0,15162857 ! regulation of endothelial cell migration GO:0010594 13 13 0,000 0,10259405 0,15150707 ! coenzyme catabolic process GO:0009109 13 13 0,000 0,10259405 0,15138577 GO:0046356|acetyl-CoA catabolic process, GO:0006099|tricarboxylic acid cycle, ! negative regulation of protein kinase cascade GO:0010741 13 13 0,000 0,10259405 0,15126466 ! purine nucleoside monophosphate metabolic process GO:0009126 13 13 0,000 0,10259405 0,15114375 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of peptide secretion GO:0002791 13 13 0,000 0,10259405 0,15102302 ! regulation of viral reproduction GO:0050792 13 13 0,000 0,10259405 0,1509025 ! nucleobase metabolic process GO:0009112 13 13 0,000 0,10259405 0,15078216 ! regulation of axonogenesis GO:0050770 14 13 0,000 0,10259405 0,15066201 ! positive regulation of neurogenesis GO:0050769 13 13 0,000 0,10259405 0,15054206 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 14 13 0,000 0,10259405 0,1504223 ! nucleotide-excision repair, DNA gap filling GO:0006297 13 13 0,000 0,10259405 0,15030272 ! vasodilation GO:0042311 14 13 0,000 0,10259405 0,15018334 ! glycosphingolipid metabolic process GO:0006687 13 13 0,000 0,10259405 0,15006415 GO:0006664|glycolipid metabolic process, ! positive regulation of locomotion GO:0040017 13 13 0,000 0,10259405 0,14994514 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, GO:0050920|regulation of chemotaxis, ! neutrophil chemotaxis GO:0030593 14 13 0,000 0,10259405 0,14982633 ! long-chain fatty acid transport GO:0015909 13 13 0,000 0,10259405 0,1497077 ! negative regulation of Wnt receptor signaling pathway GO:0030178 13 13 0,000 0,10259405 0,14958926 ! cell-cell junction organization GO:0045216 13 13 0,000 0,10259405 0,14947101 ! regulation of cell-substrate adhesion GO:0010810 14 13 0,000 0,10259405 0,14935294 GO:0001952|regulation of cell-matrix adhesion, ! negative regulation of myeloid cell differentiation GO:0045638 13 13 0,000 0,10259405 0,14923506 ! response to cytokine stimulus GO:0034097 13 13 0,000 0,10259405 0,14911737 ! activation of JUN kinase activity GO:0007257 13 13 0,000 0,10259405 0,14899986 ! terpenoid metabolic process GO:0006721 13 13 0,000 0,10259405 0,14888254 ! alkene biosynthetic process GO:0043450 13 13 0,000 0,10259405 0,1487654 GO:0019370|leukotriene biosynthetic process, ! porphyrin biosynthetic process GO:0006779 13 13 0,000 0,10259405 0,14864845 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of cytokine production GO:0001818 13 13 0,000 0,10259405 0,14853168 ! camera-type eye morphogenesis GO:0048593 13 13 0,000 0,10259405 0,14841509 ! pyrimidine nucleoside metabolic process GO:0006213 13 13 0,000 0,10259405 0,14829869 ! blastocyst development GO:0001824 13 13 0,000 0,10259405 0,14818247 ! telomere organization GO:0032200 13 13 0,000 0,10259405 0,14806643 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 13 13 0,000 0,10259405 0,14795057 ! regulation of amine transport GO:0051952 13 13 0,000 0,10259405 0,14783489 ! inner ear receptor cell differentiation GO:0060113 13 13 0,000 0,10259405 0,1477194 ! Golgi vesicle transport GO:0048193 67 67 1,000 0,1060392 0,15256069 ! muscle contraction GO:0006936 67 67 1,000 0,1060392 0,15244169 ! negative regulation of cell differentiation GO:0045596 68 67 1,000 0,1060392 0,15232287 ! purine ribonucleotide biosynthetic process GO:0009152 68 68 1,000 0,10869256 0,15601276 ! neuron fate commitment GO:0048663 14 14 0,000 0,11004303 0,15782825 ! sulfur amino acid metabolic process GO:0000096 14 14 0,000 0,11004303 0,15770552 ! regulation of interferon-gamma production GO:0032649 14 14 0,000 0,11004303 0,15758298 ! pyruvate metabolic process GO:0006090 14 14 0,000 0,11004303 0,15746063 ! cellular aldehyde metabolic process GO:0006081 14 14 0,000 0,11004303 0,15733848 ! acetyl-CoA metabolic process GO:0006084 14 14 0,000 0,11004303 0,15721651 ! cellular iron ion homeostasis GO:0006879 14 14 0,000 0,11004303 0,15709473 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 14 14 0,000 0,11004303 0,15697314 ! protein amino acid acylation GO:0043543 14 14 0,000 0,11004303 0,15685174 ! regulation of neuron projection development GO:0010975 15 14 0,000 0,11004303 0,15673052 ! protein amino acid deacetylation GO:0006476 14 14 0,000 0,11004303 0,15660949 ! aminoglycan biosynthetic process GO:0006023 14 14 0,000 0,11004303 0,15648865 ! vesicle docking GO:0048278 14 14 0,000 0,11004303 0,156368 ! superoxide metabolic process GO:0006801 15 14 0,000 0,11004303 0,15624753 ! macromolecular complex disassembly GO:0032984 15 14 0,000 0,11004303 0,15612725 ! mechanoreceptor differentiation GO:0042490 14 14 0,000 0,11004303 0,15600715 ! isoprenoid biosynthetic process GO:0008299 14 14 0,000 0,11004303 0,15588724 ! hair cycle GO:0042633 14 14 0,000 0,11004303 0,15576751 GO:0022404|molting cycle process, GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042303|molting cycle, ! negative regulation of epithelial cell proliferation GO:0050680 14 14 0,000 0,11004303 0,15564796 ! response to retinoic acid GO:0032526 14 14 0,000 0,11004303 0,1555286 GO:0033189|response to vitamin A, ! multicellular organismal response to stress GO:0033555 14 14 0,000 0,11004303 0,15540942 ! lysosome organization GO:0007040 14 14 0,000 0,11004303 0,15529043 ! D-ribose metabolic process GO:0006014 14 14 0,000 0,11004303 0,15517161 ! peptide transport GO:0015833 14 14 0,000 0,11004303 0,15505298 ! peptide cross-linking GO:0018149 14 14 0,000 0,11004303 0,15493453 ! regulation of behavior GO:0050795 14 14 0,000 0,11004303 0,15481626 ! vitamin biosynthetic process GO:0009110 14 14 0,000 0,11004303 0,15469817 ! response to organic cyclic substance GO:0014070 15 14 0,000 0,11004303 0,15458026 ! leukotriene metabolic process GO:0006691 14 14 0,000 0,11004303 0,15446253 ! regulation of vasoconstriction GO:0019229 14 14 0,000 0,11004303 0,15434497 ! formation of primary germ layer GO:0001704 14 14 0,000 0,11004303 0,1542276 GO:0001707|mesoderm formation, ! collagen fibril organization GO:0030199 14 14 0,000 0,11004303 0,15411041 ! proteoglycan biosynthetic process GO:0030166 14 14 0,000 0,11004303 0,15399339 ! regulation of blood coagulation GO:0030193 15 14 0,000 0,11004303 0,15387655 ! positive regulation of inflammatory response GO:0050729 14 14 0,000 0,11004303 0,15375989 ! positive regulation of osteoblast differentiation GO:0045669 14 14 0,000 0,11004303 0,15364341 ! neuromuscular process controlling balance GO:0050885 14 14 0,000 0,11004303 0,1535271 ! aspartate family amino acid metabolic process GO:0009066 14 14 0,000 0,11004303 0,15341096 ! response to molecule of bacterial origin GO:0002237 14 14 0,000 0,11004303 0,15329501 ! negative regulation of protein polymerization GO:0032272 14 14 0,000 0,11004303 0,15317923 ! regulation of translation GO:0006417 69 69 1,000 0,11136378 0,15490071 ! sensory perception of sound GO:0007605 71 69 1,000 0,11136378 0,1547839 GO:0050954|sensory perception of mechanical stimulus, ! response to nutrient levels GO:0031667 69 69 1,000 0,11136378 0,15466725 ! regulation of mitotic cell cycle GO:0007346 72 69 1,000 0,11136378 0,15455079 ! wound healing GO:0042060 74 70 1,000 0,1140524 0,15816295 ! oxidative phosphorylation GO:0006119 71 71 1,000 0,11675795 0,16179316 ! calcium ion homeostasis GO:0055074 71 71 1,000 0,11675795 0,1616716 GO:0006874|cellular calcium ion homeostasis, ! negative regulation of signal transduction GO:0009968 71 71 1,000 0,11675795 0,16155022 ! positive regulation of fibroblast proliferation GO:0048146 15 15 0,000 0,11743125 0,16235993 ! negative regulation of actin filament depolymerization GO:0030835 15 15 0,000 0,11743125 0,16223823 ! positive regulation of ossification GO:0045778 15 15 0,000 0,11743125 0,1621167 GO:0046852|positive regulation of bone remodeling, GO:0034105|positive regulation of tissue remodeling, ! negative regulation of protein complex assembly GO:0031333 15 15 0,000 0,11743125 0,16199535 ! protein amino acid O-linked glycosylation GO:0006493 15 15 0,000 0,11743125 0,16187419 ! cellular polysaccharide biosynthetic process GO:0033692 15 15 0,000 0,11743125 0,16175321 ! proteoglycan metabolic process GO:0006029 15 15 0,000 0,11743125 0,16163241 ! response to vitamin GO:0033273 15 15 0,000 0,11743125 0,16151179 ! regulation of transcription factor import into nucleus GO:0042990 15 15 0,000 0,11743125 0,16139134 ! odontogenesis of dentine-containing tooth GO:0042475 15 15 0,000 0,11743125 0,16127108 ! ovarian follicle development GO:0001541 15 15 0,000 0,11743125 0,161151 ! antigen processing and presentation of peptide antigen GO:0048002 15 15 0,000 0,11743125 0,1610311 ! regulation of smooth muscle contraction GO:0006940 15 15 0,000 0,11743125 0,16091137 ! deoxyribonucleotide metabolic process GO:0009262 15 15 0,000 0,11743125 0,16079182 ! complement activation, classical pathway GO:0006958 15 15 0,000 0,11743125 0,16067245 ! heme metabolic process GO:0042168 15 15 0,000 0,11743125 0,16055326 ! mesoderm morphogenesis GO:0048332 15 15 0,000 0,11743125 0,16043424 ! chromosome condensation GO:0030261 15 15 0,000 0,11743125 0,1603154 ! response to mechanical stimulus GO:0009612 15 15 0,000 0,11743125 0,16019674 ! hydrogen peroxide metabolic process GO:0042743 15 15 0,000 0,11743125 0,16007825 ! regulation of biomineral formation GO:0070167 15 15 0,000 0,11743125 0,15995994 GO:0030500|regulation of bone mineralization, ! cyclic nucleotide biosynthetic process GO:0009190 15 15 0,000 0,11743125 0,1598418 ! cholesterol biosynthetic process GO:0006695 15 15 0,000 0,11743125 0,15972383 ! phospholipid transport GO:0015914 15 15 0,000 0,11743125 0,15960604 ! leukocyte homeostasis GO:0001776 15 15 0,000 0,11743125 0,15948843 ! regulation of cytokine secretion GO:0050707 15 15 0,000 0,11743125 0,15937098 ! glutathione metabolic process GO:0006749 16 15 0,000 0,11743125 0,15925371 ! nicotinamide metabolic process GO:0006769 15 15 0,000 0,11743125 0,15913661 GO:0046496|nicotinamide nucleotide metabolic process, ! positive regulation of myeloid cell differentiation GO:0045639 16 15 0,000 0,11743125 0,15901969 ! cellular alkene metabolic process GO:0043449 15 15 0,000 0,11743125 0,15890293 ! negative regulation of transcription factor activity GO:0043433 16 15 0,000 0,11743125 0,15878635 GO:0090048|negative regulation of transcription regulator activity, ! somatic diversification of immune receptors GO:0002200 15 15 0,000 0,11743125 0,15866994 ! protein homooligomerization GO:0051260 15 15 0,000 0,11743125 0,15855369 ! muscle system process GO:0003012 72 72 1,000 0,11947998 0,16120176 ! positive regulation of hydrolase activity GO:0051345 72 72 1,000 0,11947998 0,16108384 ! response to extracellular stimulus GO:0009991 72 72 1,000 0,11947998 0,16096609 ! negative regulation of adenylate cyclase activity GO:0007194 16 16 0,000 0,12475921 0,1679556 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! alkaloid metabolic process GO:0009820 16 16 0,000 0,12475921 0,167833 ! regulation of synaptic plasticity GO:0048167 16 16 0,000 0,12475921 0,16771059 ! spliceosomal snRNP biogenesis GO:0000387 16 16 0,000 0,12475921 0,16758835 ! learning GO:0007612 16 16 0,000 0,12475921 0,16746629 ! circadian rhythm GO:0007623 16 16 0,000 0,12475921 0,16734441 ! inner ear morphogenesis GO:0042472 16 16 0,000 0,12475921 0,1672227 ! positive regulation of mitosis GO:0045840 16 16 0,000 0,12475921 0,16710117 GO:0051785|positive regulation of nuclear division, ! vacuole organization GO:0007033 16 16 0,000 0,12475921 0,16697982 ! vesicle targeting GO:0006903 17 16 0,000 0,12475921 0,16685865 ! segmentation GO:0035282 17 16 0,000 0,12475921 0,16673765 ! fatty acid beta-oxidation GO:0006635 16 16 0,000 0,12475921 0,16661682 ! triglyceride metabolic process GO:0006641 16 16 0,000 0,12475921 0,16649617 ! iron ion homeostasis GO:0055072 16 16 0,000 0,12475921 0,1663757 ! positive regulation of cell development GO:0010720 16 16 0,000 0,12475921 0,1662554 ! regulation of myeloid leukocyte differentiation GO:0002761 17 16 0,000 0,12475921 0,16613527 ! regulation of systemic arterial blood pressure GO:0003073 17 16 0,000 0,12475921 0,16601532 ! cell fate specification GO:0001708 16 16 0,000 0,12475921 0,16589554 ! pentose metabolic process GO:0019321 16 16 0,000 0,12475921 0,16577593 ! fatty acid transport GO:0015908 16 16 0,000 0,12475921 0,1656565 ! regulation of microtubule cytoskeleton organization GO:0070507 16 16 0,000 0,12475921 0,16553723 ! cofactor catabolic process GO:0051187 16 16 0,000 0,12475921 0,16541814 ! ethanolamine and derivative metabolic process GO:0042439 17 16 0,000 0,12475921 0,16529922 ! serine family amino acid metabolic process GO:0009069 16 16 0,000 0,12475921 0,16518047 ! glutamine family amino acid catabolic process GO:0009065 17 16 0,000 0,12475921 0,16506189 ! porphyrin metabolic process GO:0006778 16 16 0,000 0,12475921 0,16494348 GO:0033013|tetrapyrrole metabolic process, ! regulation of JUN kinase activity GO:0043506 17 16 0,000 0,12475921 0,16482524 GO:0043507|positive regulation of JUN kinase activity, ! regulation of cell morphogenesis involved in differentiation GO:0010769 17 16 0,000 0,12475921 0,16470717 ! regulation of coagulation GO:0050818 17 16 0,000 0,12475921 0,16458927 ! coenzyme metabolic process GO:0006732 75 74 1,000 0,12497173 0,16475172 ! ribonucleotide biosynthetic process GO:0009260 75 75 1,000 0,12774057 0,16828153 ! negative regulation of cell communication GO:0010648 76 76 1,000 0,13052414 0,17182571 ! positive regulation of multicellular organismal process GO:0051240 76 76 1,000 0,13052414 0,17170306 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 17 17 0,000 0,13202738 0,17355667 ! regulation of smooth muscle cell proliferation GO:0048660 17 17 0,000 0,13202738 0,17343297 ! phosphoinositide biosynthetic process GO:0046489 17 17 0,000 0,13202738 0,17330944 ! regulation of transmembrane transport GO:0034762 17 17 0,000 0,13202738 0,17318609 ! nucleotide-excision repair, DNA damage removal GO:0000718 18 17 0,000 0,13202738 0,17306291 ! sensory perception of smell GO:0007608 17 17 0,000 0,13202738 0,17293991 ! glucose transport GO:0015758 17 17 0,000 0,13202738 0,17281708 ! cell junction assembly GO:0034329 18 17 0,000 0,13202738 0,17269443 ! tissue remodeling GO:0048771 17 17 0,000 0,13202738 0,17257195 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 17 17 0,000 0,13202738 0,17244965 ! embryonic skeletal system morphogenesis GO:0048704 17 17 0,000 0,13202738 0,17232752 ! cellular carbohydrate biosynthetic process GO:0034637 17 17 0,000 0,13202738 0,17220556 ! development of primary male sexual characteristics GO:0046546 17 17 0,000 0,13202738 0,17208377 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 17 17 0,000 0,13202738 0,17196216 ! cell recognition GO:0008037 18 17 0,000 0,13202738 0,17184072 ! regulation of oxidoreductase activity GO:0051341 17 17 0,000 0,13202738 0,17171945 ! positive regulation of protein secretion GO:0050714 17 17 0,000 0,13202738 0,17159835 ! regulation of osteoblast differentiation GO:0045667 17 17 0,000 0,13202738 0,17147742 ! pyridine nucleotide metabolic process GO:0019362 17 17 0,000 0,13202738 0,17135666 ! pigmentation GO:0043473 17 17 0,000 0,13202738 0,17123607 ! myeloid leukocyte activation GO:0002274 18 17 0,000 0,13202738 0,17111565 ! adult locomotory behavior GO:0008344 17 17 0,000 0,13202738 0,1709954 ! embryonic organ development GO:0048568 17 17 0,000 0,13202738 0,17087532 ! regulation of calcium ion transport GO:0051924 17 17 0,000 0,13202738 0,17075541 ! liver development GO:0001889 17 17 0,000 0,13202738 0,17063566 ! gene silencing GO:0016458 17 17 0,000 0,13202738 0,17051609 ! cellular metal ion homeostasis GO:0006875 77 77 1,000 0,13332202 0,17206757 ! microtubule-based movement GO:0007018 82 78 1,000 0,13613381 0,17557355 ! metal ion homeostasis GO:0055065 78 78 1,000 0,13613381 0,17545077 ! regulation of immune response GO:0050776 78 78 1,000 0,13613381 0,17532817 ! mRNA export from nucleus GO:0006406 18 18 0,000 0,13923624 0,1791986 ! regulation of cell projection organization GO:0031344 19 18 0,000 0,13923624 0,17907355 ! regulation of cellular catabolic process GO:0031329 18 18 0,000 0,13923624 0,17894867 ! icosanoid biosynthetic process GO:0046456 18 18 0,000 0,13923624 0,17882397 ! meiosis I GO:0007127 18 18 0,000 0,13923624 0,17869944 ! epidermal growth factor receptor signaling pathway GO:0007173 18 18 0,000 0,13923624 0,17857508 ! regulation of metal ion transport GO:0010959 18 18 0,000 0,13923624 0,1784509 ! membrane docking GO:0022406 18 18 0,000 0,13923624 0,17832689 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 18 18 0,000 0,13923624 0,17820305 ! negative regulation of response to external stimulus GO:0032102 18 18 0,000 0,13923624 0,17807938 ! hexose transport GO:0008645 18 18 0,000 0,13923624 0,17795589 GO:0015749|monosaccharide transport, ! cholesterol homeostasis GO:0042632 18 18 0,000 0,13923624 0,17783257 GO:0055092|sterol homeostasis, ! neutral lipid metabolic process GO:0006638 18 18 0,000 0,13923624 0,17770941 GO:0006639|acylglycerol metabolic process, ! negative regulation of DNA binding GO:0043392 19 18 0,000 0,13923624 0,17758643 ! ceramide metabolic process GO:0006672 18 18 0,000 0,13923624 0,17746362 GO:0046519|sphingoid metabolic process, ! ribonucleoside monophosphate metabolic process GO:0009161 18 18 0,000 0,13923624 0,17734098 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! telencephalon development GO:0021537 19 18 0,000 0,13923624 0,1772185 ! hexose biosynthetic process GO:0019319 18 18 0,000 0,13923624 0,1770962 ! negative regulation of MAP kinase activity GO:0043407 18 18 0,000 0,13923624 0,17697406 ! BMP signaling pathway GO:0030509 18 18 0,000 0,13923624 0,1768521 ! regulation of microtubule-based process GO:0032886 18 18 0,000 0,13923624 0,1767303 ! symbiosis, encompassing mutualism through parasitism GO:0044403 18 18 0,000 0,13923624 0,17660867 ! establishment of vesicle localization GO:0051650 19 18 0,000 0,13923624 0,1764872 ! tube development GO:0035295 83 81 1,000 0,14464845 0,18322137 ! activation of adenylate cyclase activity GO:0007190 19 19 0,000 0,14638628 0,18529527 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 19 19 0,000 0,14638628 0,18516809 GO:0006956|complement activation, ! feeding behavior GO:0007631 19 19 0,000 0,14638628 0,18504109 ! regulation of endothelial cell proliferation GO:0001936 19 19 0,000 0,14638628 0,18491426 ! peroxisome organization GO:0007031 19 19 0,000 0,14638628 0,18478761 ! regulation of striated muscle tissue development GO:0016202 20 19 0,000 0,14638628 0,18466113 ! metanephros development GO:0001656 19 19 0,000 0,14638628 0,18453482 ! nuclear-transcribed mRNA catabolic process GO:0000956 19 19 0,000 0,14638628 0,18440868 ! regulation of protein stability GO:0031647 19 19 0,000 0,14638628 0,18428272 ! hormone biosynthetic process GO:0042446 19 19 0,000 0,14638628 0,18415693 ! biogenic amine biosynthetic process GO:0042401 20 19 0,000 0,14638628 0,18403131 ! dorsal/ventral pattern formation GO:0009953 19 19 0,000 0,14638628 0,18390587 ! eye morphogenesis GO:0048592 19 19 0,000 0,14638628 0,18378059 ! regulation of cell shape GO:0008360 21 19 0,000 0,14638628 0,18365548 ! placenta development GO:0001890 19 19 0,000 0,14638628 0,18353055 ! vesicle localization GO:0051648 20 19 0,000 0,14638628 0,18340578 ! blood vessel morphogenesis GO:0048514 84 83 1,000 0,15038698 0,18829022 ! cellular amino acid derivative metabolic process GO:0006575 87 84 1,000 0,15327371 0,19177423 ! regulation of muscle development GO:0048634 21 20 0,000 0,15347795 0,1918995 ! negative regulation of cell adhesion GO:0007162 21 20 0,000 0,15347795 0,1917694 ! negative regulation of binding GO:0051100 21 20 0,000 0,15347795 0,19163947 ! organic ether metabolic process GO:0018904 20 20 0,000 0,15347795 0,19150972 GO:0006662|glycerol ether metabolic process, ! nucleus organization GO:0006997 20 20 0,000 0,15347795 0,19138015 ! phagocytosis GO:0006909 21 20 0,000 0,15347795 0,19125075 ! unsaturated fatty acid biosynthetic process GO:0006636 20 20 0,000 0,15347795 0,19112153 ! protein targeting to membrane GO:0006612 22 20 0,000 0,15347795 0,19099248 ! cyclic nucleotide metabolic process GO:0009187 20 20 0,000 0,15347795 0,19086361 ! chromatin remodeling GO:0006338 20 20 0,000 0,15347795 0,1907349 ! lipid oxidation GO:0034440 20 20 0,000 0,15347795 0,19060638 GO:0019395|fatty acid oxidation, ! female gamete generation GO:0007292 20 20 0,000 0,15347795 0,19047802 ! negative regulation of neuron apoptosis GO:0043524 21 20 0,000 0,15347795 0,19034984 ! monosaccharide biosynthetic process GO:0046364 20 20 0,000 0,15347795 0,19022183 ! RNA modification GO:0009451 20 20 0,000 0,15347795 0,19009399 ! single fertilization GO:0007338 21 20 0,000 0,15347795 0,18996633 ! regulation of cellular localization GO:0060341 86 85 1,000 0,15617157 0,19317061 ! nitrogen compound biosynthetic process GO:0044271 86 85 1,000 0,15617157 0,19304105 ! positive regulation of cell differentiation GO:0045597 87 85 1,000 0,15617157 0,19291166 ! positive regulation of response to stimulus GO:0048584 86 85 1,000 0,15617157 0,19278245 ! regulation of anatomical structure morphogenesis GO:0022603 90 86 1,000 0,1590802 0,1962415 ! mitotic sister chromatid segregation GO:0000070 21 21 0,000 0,16051173 0,197875 ! mRNA catabolic process GO:0006402 21 21 0,000 0,16051173 0,19774273 ! positive regulation of adenylate cyclase activity GO:0045762 21 21 0,000 0,16051173 0,19761064 GO:0051349|positive regulation of lyase activity, GO:0031281|positive regulation of cyclase activity, ! protein amino acid lipidation GO:0006497 21 21 0,000 0,16051173 0,19747872 ! receptor-mediated endocytosis GO:0006898 21 21 0,000 0,16051173 0,19734698 ! ear morphogenesis GO:0042471 21 21 0,000 0,16051173 0,19721542 ! organic anion transport GO:0015711 21 21 0,000 0,16051173 0,19708403 ! cholesterol transport GO:0030301 21 21 0,000 0,16051173 0,19695281 GO:0015918|sterol transport, ! spliceosome assembly GO:0000245 22 21 0,000 0,16051173 0,19682177 ! regulation of Rab protein signal transduction GO:0032483 21 21 0,000 0,16051173 0,19669091 GO:0032313|regulation of Rab GTPase activity, ! regulation of protein import into nucleus GO:0042306 21 21 0,000 0,16051173 0,19656022 ! heart development GO:0007507 90 87 1,000 0,16199922 0,19825004 ! purine nucleotide biosynthetic process GO:0006164 88 88 1,000 0,16492827 0,2017006 ! positive regulation of transcription factor activity GO:0051091 22 22 0,000 0,16748809 0,20469533 GO:0090047|positive regulation of transcription regulator activity, ! RNA export from nucleus GO:0006405 22 22 0,000 0,16748809 0,20455968 ! sister chromatid segregation GO:0000819 22 22 0,000 0,16748809 0,20442421 ! regulation of ion transport GO:0043269 22 22 0,000 0,16748809 0,20428892 ! odontogenesis GO:0042476 22 22 0,000 0,16748809 0,2041538 ! cell junction organization GO:0034330 23 22 0,000 0,16748809 0,20401887 ! hormone-mediated signaling GO:0009755 22 22 0,000 0,16748809 0,20388412 ! embryonic skeletal system development GO:0048706 22 22 0,000 0,16748809 0,20374954 ! ovulation cycle process GO:0022602 22 22 0,000 0,16748809 0,20361514 ! spindle organization GO:0007051 22 22 0,000 0,16748809 0,20348092 ! pigment biosynthetic process GO:0046148 22 22 0,000 0,16748809 0,20334687 ! cell chemotaxis GO:0060326 23 22 0,000 0,16748809 0,203213 GO:0030595|leukocyte chemotaxis, ! respiratory gaseous exchange GO:0007585 22 22 0,000 0,16748809 0,20307931 ! erythrocyte differentiation GO:0030218 23 22 0,000 0,16748809 0,20294579 ! male sex differentiation GO:0046661 22 22 0,000 0,16748809 0,20281245 ! sterol biosynthetic process GO:0016126 22 22 0,000 0,16748809 0,20267929 ! neuron migration GO:0001764 22 22 0,000 0,16748809 0,20254629 ! regulation of Wnt receptor signaling pathway GO:0030111 23 22 0,000 0,16748809 0,20241348 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 22 22 0,000 0,16748809 0,20228083 ! fatty acid catabolic process GO:0009062 23 22 0,000 0,16748809 0,20214836 ! aerobic respiration GO:0009060 22 22 0,000 0,16748809 0,20201607 ! cytokine production GO:0001816 22 22 0,000 0,16748809 0,20188395 ! pyrimidine nucleotide metabolic process GO:0006220 22 22 0,000 0,16748809 0,20175199 ! cellular di-, tri-valent inorganic cation homeostasis GO:0030005 89 89 1,000 0,16786701 0,20207635 ! negative regulation of cell cycle GO:0045786 92 91 1,000 0,17377209 0,20904828 ! di-, tri-valent inorganic cation homeostasis GO:0055066 91 91 1,000 0,17377209 0,20891191 ! response to hydrogen peroxide GO:0042542 24 23 0,000 0,17440748 0,20953911 ! epithelial cell differentiation GO:0030855 23 23 0,000 0,17440748 0,2094026 ! viral infectious cycle GO:0019058 23 23 0,000 0,17440748 0,20926627 ! regulation of hormone secretion GO:0046883 23 23 0,000 0,17440748 0,20913012 ! response to estrogen stimulus GO:0043627 23 23 0,000 0,17440748 0,20899414 ! negative regulation of protein complex disassembly GO:0043242 23 23 0,000 0,17440748 0,20885834 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 23 23 0,000 0,17440748 0,20872272 ! induction of apoptosis by extracellular signals GO:0008624 23 23 0,000 0,17440748 0,20858727 ! regulation of ARF protein signal transduction GO:0032012 23 23 0,000 0,17440748 0,208452 ! endocrine system development GO:0035270 23 23 0,000 0,17440748 0,20831691 ! lipoprotein biosynthetic process GO:0042158 23 23 0,000 0,17440748 0,20818199 ! female gonad development GO:0008585 23 23 0,000 0,17440748 0,20804724 ! lipid homeostasis GO:0055088 23 23 0,000 0,17440748 0,20791267 ! calcium-mediated signaling GO:0019722 23 23 0,000 0,17440748 0,20777827 ! regulation of JNK cascade GO:0046328 25 23 0,000 0,17440748 0,20764405 ! cell projection assembly GO:0030031 25 23 0,000 0,17440748 0,20751 ! visual perception GO:0007601 93 92 1,000 0,17673776 0,21014689 GO:0050953|sensory perception of light stimulus, ! fatty acid metabolic process GO:0006631 93 92 1,000 0,17673776 0,2100114 ! positive regulation of immune system process GO:0002684 92 92 1,000 0,17673776 0,20987609 ! tissue morphogenesis GO:0048729 94 93 1,000 0,17971172 0,21327025 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 26 24 0,000 0,18127036 0,21498152 ! cellular amino acid biosynthetic process GO:0008652 24 24 0,000 0,18127036 0,21484327 ! glucose homeostasis GO:0042593 24 24 0,000 0,18127036 0,21470519 GO:0033500|carbohydrate homeostasis, ! heterocycle biosynthetic process GO:0018130 24 24 0,000 0,18127036 0,21456729 ! erythrocyte homeostasis GO:0034101 25 24 0,000 0,18127036 0,21442957 ! ovulation cycle GO:0042698 24 24 0,000 0,18127036 0,21429203 ! fertilization GO:0009566 25 24 0,000 0,18127036 0,21415467 ! oxidoreduction coenzyme metabolic process GO:0006733 24 24 0,000 0,18127036 0,21401747 ! androgen receptor signaling pathway GO:0030521 24 24 0,000 0,18127036 0,21388046 ! glucan metabolic process GO:0044042 25 24 0,000 0,18127036 0,21374362 GO:0006073|cellular glucan metabolic process, GO:0005977|glycogen metabolic process, ! epidermis development GO:0008544 94 94 1,000 0,18269364 0,21528413 ! cofactor metabolic process GO:0051186 95 94 1,000 0,18269364 0,21514657 ! regulation of actin filament polymerization GO:0030833 25 25 0,000 0,18807719 0,22134499 ! negative regulation of secretion GO:0051048 26 25 0,000 0,18807719 0,22120374 ! protein amino acid N-linked glycosylation GO:0006487 25 25 0,000 0,18807719 0,22106266 ! sensory perception of chemical stimulus GO:0007606 25 25 0,000 0,18807719 0,22092177 ! cellular component disassembly GO:0022411 26 25 0,000 0,18807719 0,22078105 ! endosome transport GO:0016197 25 25 0,000 0,18807719 0,22064052 ! alcohol biosynthetic process GO:0046165 25 25 0,000 0,18807719 0,22050016 ! development of primary female sexual characteristics GO:0046545 25 25 0,000 0,18807719 0,22035998 GO:0046660|female sex differentiation, ! polysaccharide biosynthetic process GO:0000271 25 25 0,000 0,18807719 0,22021998 ! excretion GO:0007588 25 25 0,000 0,18807719 0,22008016 ! positive regulation of DNA binding GO:0043388 26 25 0,000 0,18807719 0,21994052 ! generation of a signal involved in cell-cell signaling GO:0003001 27 25 0,000 0,18807719 0,21980105 ! gastrulation GO:0007369 25 25 0,000 0,18807719 0,21966176 ! heart morphogenesis GO:0003007 25 25 0,000 0,18807719 0,21952264 ! icosanoid metabolic process GO:0006690 25 25 0,000 0,18807719 0,21938371 ! regulation of endocytosis GO:0030100 25 25 0,000 0,18807719 0,21924494 ! positive regulation of cytokine production GO:0001819 25 25 0,000 0,18807719 0,21910636 ! posttranscriptional regulation of gene expression GO:0010608 98 98 1,000 0,19469449 0,2266721 ! glycoprotein metabolic process GO:0009100 99 98 1,000 0,19469449 0,226529 ! endocytosis GO:0006897 99 98 1,000 0,19469449 0,22638608 GO:0010324|membrane invagination, ! positive regulation of binding GO:0051099 27 26 0,000 0,1948284 0,22639896 ! positive regulation of defense response GO:0031349 26 26 0,000 0,1948284 0,2262563 ! glycolysis GO:0006096 26 26 0,000 0,1948284 0,22611382 ! transforming growth factor beta receptor signaling pathway GO:0007179 26 26 0,000 0,1948284 0,22597152 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 26 26 0,000 0,1948284 0,2258294 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 26 26 0,000 0,1948284 0,22568746 ! negative regulation of cell migration GO:0030336 26 26 0,000 0,1948284 0,2255457 ! cellular defense response GO:0006968 26 26 0,000 0,1948284 0,22540411 ! positive regulation of cytokine biosynthetic process GO:0042108 26 26 0,000 0,1948284 0,2252627 ! regulation of protein secretion GO:0050708 26 26 0,000 0,1948284 0,22512147 ! germ cell development GO:0007281 27 26 0,000 0,1948284 0,22498042 ! regulation of blood vessel size GO:0050880 27 26 0,000 0,1948284 0,22483954 GO:0035150|regulation of tube size, ! pigment metabolic process GO:0042440 26 26 0,000 0,1948284 0,22469884 ! ectoderm development GO:0007398 99 99 1,000 0,1977114 0,22788125 ! response to other organism GO:0051707 101 100 1,000 0,20073438 0,23122092 ! chloride transport GO:0006821 27 27 0,000 0,20152446 0,231986 ! regulation of neurotransmitter levels GO:0001505 31 27 0,000 0,20152446 0,23184119 ! energy reserve metabolic process GO:0006112 28 27 0,000 0,20152446 0,23169656 ! learning or memory GO:0007611 28 27 0,000 0,20152446 0,23155211 ! monocarboxylic acid transport GO:0015718 27 27 0,000 0,20152446 0,23140784 ! cAMP-mediated signaling GO:0019933 27 27 0,000 0,20152446 0,23126375 ! peptide metabolic process GO:0006518 29 27 0,000 0,20152446 0,23111984 ! inner ear development GO:0048839 27 27 0,000 0,20152446 0,23097611 ! defense response to bacterium GO:0042742 27 27 0,000 0,20152446 0,23083256 ! isoprenoid metabolic process GO:0006720 27 27 0,000 0,20152446 0,23068918 ! glutamine family amino acid metabolic process GO:0009064 28 27 0,000 0,20152446 0,23054599 ! cell growth GO:0016049 27 27 0,000 0,20152446 0,23040297 ! tRNA aminoacylation for protein translation GO:0006418 28 28 0,000 0,2081658 0,23784847 GO:0043038|amino acid activation, GO:0043039|tRNA aminoacylation, ! stress-activated protein kinase signaling pathway GO:0031098 28 28 0,000 0,2081658 0,2377011 GO:0007254|JNK cascade, ! neuromuscular process GO:0050905 28 28 0,000 0,2081658 0,23755392 ! carbohydrate transport GO:0008643 28 28 0,000 0,2081658 0,23740692 ! regulation of muscle contraction GO:0006937 28 28 0,000 0,2081658 0,2372601 ! unsaturated fatty acid metabolic process GO:0033559 28 28 0,000 0,2081658 0,23711346 ! sulfur compound biosynthetic process GO:0044272 28 28 0,000 0,2081658 0,236967 ! histone modification GO:0016570 28 28 0,000 0,2081658 0,23682073 ! developmental growth GO:0048589 28 28 0,000 0,2081658 0,23667463 ! cartilage development GO:0051216 29 28 0,000 0,2081658 0,23652871 ! positive regulation of cell cycle GO:0045787 29 29 0,000 0,21475287 0,24386293 ! glycerophospholipid biosynthetic process GO:0046474 30 29 0,000 0,21475287 0,24371277 ! viral reproductive process GO:0022415 29 29 0,000 0,21475287 0,24356279 ! phosphoinositide metabolic process GO:0030384 29 29 0,000 0,21475287 0,243413 ! leukocyte migration GO:0050900 30 29 0,000 0,21475287 0,24326339 ! branching morphogenesis of a tube GO:0048754 29 29 0,000 0,21475287 0,24311396 ! antigen processing and presentation GO:0019882 29 29 0,000 0,21475287 0,24296472 ! DNA-dependent DNA replication GO:0006261 29 29 0,000 0,21475287 0,24281566 ! tRNA processing GO:0008033 29 29 0,000 0,21475287 0,24266679 ! covalent chromatin modification GO:0016569 29 29 0,000 0,21475287 0,24251809 ! adult behavior GO:0030534 30 29 0,000 0,21475287 0,24236958 ! regulation of protein polymerization GO:0032271 29 29 0,000 0,21475287 0,24222126 ! positive regulation of protein transport GO:0051222 29 29 0,000 0,21475287 0,24207311 ! transition metal ion transport GO:0000041 31 30 0,000 0,22128608 0,249285 ! RNA catabolic process GO:0006401 30 30 0,000 0,22128608 0,24913271 ! ER to Golgi vesicle-mediated transport GO:0006888 30 30 0,000 0,22128608 0,24898062 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 30 30 0,000 0,22128608 0,24882871 ! neuropeptide signaling pathway GO:0007218 30 30 0,000 0,22128608 0,24867698 ! activation of phospholipase C activity GO:0007202 30 30 0,000 0,22128608 0,24852544 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of response to external stimulus GO:0032103 30 30 0,000 0,22128608 0,24837409 ! skeletal system morphogenesis GO:0048705 31 30 0,000 0,22128608 0,24822292 ! regulation of ossification GO:0030278 30 30 0,000 0,22128608 0,24807193 ! vascular process in circulatory system GO:0003018 31 30 0,000 0,22128608 0,24792113 ! immunoglobulin mediated immune response GO:0016064 30 30 0,000 0,22128608 0,24777051 GO:0019724|B cell mediated immunity, ! regulation of inflammatory response GO:0050727 30 30 0,000 0,22128608 0,24762007 ! water-soluble vitamin metabolic process GO:0006767 30 30 0,000 0,22128608 0,24746981 ! cellular amino acid derivative biosynthetic process GO:0042398 31 30 0,000 0,22128608 0,24731974 ! establishment of organelle localization GO:0051656 31 30 0,000 0,22128608 0,24716985 ! negative regulation of cytoskeleton organization GO:0051494 32 31 0,000 0,22776589 0,25425351 ! lipoprotein metabolic process GO:0042157 31 31 0,000 0,22776589 0,2540996 ! positive regulation of phospholipase activity GO:0010518 31 31 0,000 0,22776589 0,25394588 ! glycerolipid biosynthetic process GO:0045017 32 31 0,000 0,22776589 0,25379235 ! digestion GO:0007586 31 31 0,000 0,22776589 0,253639 ! regulation of heart contraction GO:0008016 31 31 0,000 0,22776589 0,25348583 ! sphingolipid metabolic process GO:0006665 31 31 0,000 0,22776589 0,25333286 ! camera-type eye development GO:0043010 31 31 0,000 0,22776589 0,25318006 ! extracellular matrix organization GO:0030198 31 31 0,000 0,22776589 0,25302745 ! ribonucleoprotein complex assembly GO:0022618 32 31 0,000 0,22776589 0,25287503 ! regulation of myeloid cell differentiation GO:0045637 32 31 0,000 0,22776589 0,25272278 ! negative regulation of cell motion GO:0051271 31 31 0,000 0,22776589 0,25257072 ! cell redox homeostasis GO:0045454 32 32 0,000 0,23419272 0,2595413 ! glucose catabolic process GO:0006007 32 32 0,000 0,23419272 0,25938533 ! lipid modification GO:0030258 32 32 0,000 0,23419272 0,25922954 ! regulation of phospholipase activity GO:0010517 32 32 0,000 0,23419272 0,25907394 ! glycosaminoglycan metabolic process GO:0030203 34 32 0,000 0,23419272 0,25891853 ! regulation of vesicle-mediated transport GO:0060627 33 32 0,000 0,23419272 0,2587633 ! cell maturation GO:0048469 32 32 0,000 0,23419272 0,25860826 ! morphogenesis of a branching structure GO:0001763 32 32 0,000 0,23419272 0,25845341 ! kidney development GO:0001822 32 32 0,000 0,23419272 0,25829874 ! positive regulation of lipase activity GO:0060193 32 32 0,000 0,23419272 0,25814425 ! regulation of cellular response to stress GO:0080135 35 33 0,000 0,24056699 0,26501194 ! amino acid transport GO:0006865 33 33 0,000 0,24056699 0,26485363 ! regulation of protein complex assembly GO:0043254 33 33 0,000 0,24056699 0,2646955 ! membrane lipid metabolic process GO:0006643 33 33 0,000 0,24056699 0,26453757 ! regulation of neuron differentiation GO:0045664 34 33 0,000 0,24056699 0,26437983 ! regulation of synaptic transmission GO:0050804 33 33 0,000 0,24056699 0,26422227 ! regulation of bone remodeling GO:0046850 34 34 0,000 0,24688913 0,27100457 ! ear development GO:0043583 34 34 0,000 0,24688913 0,27084326 ! cellular polysaccharide metabolic process GO:0044264 35 34 0,000 0,24688913 0,27068214 ! coenzyme biosynthetic process GO:0009108 34 34 0,000 0,24688913 0,27052121 ! nucleoside monophosphate biosynthetic process GO:0009124 34 34 0,000 0,24688913 0,27036047 ! secondary metabolic process GO:0019748 34 34 0,000 0,24688913 0,27019992 ! viral reproduction GO:0016032 34 34 0,000 0,24688913 0,27003957 ! acute inflammatory response GO:0002526 35 35 0,000 0,25315956 0,27673373 ! regulation of cytokine biosynthetic process GO:0042035 35 35 0,000 0,25315956 0,27656969 ! mesoderm development GO:0007498 35 35 0,000 0,25315956 0,27640584 ! multicellular organism reproduction GO:0032504 36 35 0,000 0,25315956 0,27624219 GO:0048609|reproductive process in a multicellular organism, ! regulation of cell morphogenesis GO:0022604 38 35 0,000 0,25315956 0,27607873 ! regulation of tissue remodeling GO:0034103 35 35 0,000 0,25315956 0,27591547 ! inorganic anion transport GO:0015698 35 35 0,000 0,25315956 0,2757524 ! response to steroid hormone stimulus GO:0048545 35 35 0,000 0,25315956 0,27558952 ! aminoglycan metabolic process GO:0006022 38 36 0,000 0,25937868 0,28219298 ! oxygen and reactive oxygen species metabolic process GO:0006800 37 36 0,000 0,25937868 0,28202649 ! regulation of mitosis GO:0007088 37 36 0,000 0,25937868 0,2818602 GO:0051783|regulation of nuclear division, ! embryonic limb morphogenesis GO:0030326 36 36 0,000 0,25937868 0,28169411 GO:0035113|embryonic appendage morphogenesis, ! female pregnancy GO:0007565 37 36 0,000 0,25937868 0,28152821 ! RNA elongation from RNA polymerase II promoter GO:0006368 36 36 0,000 0,25937868 0,28136251 ! integrin-mediated signaling pathway GO:0007229 36 36 0,000 0,25937868 0,281197 ! regulation of transmission of nerve impulse GO:0051969 36 36 0,000 0,25937868 0,28103169 ! gonad development GO:0008406 36 36 0,000 0,25937868 0,28086657 ! regulation of lipase activity GO:0060191 36 36 0,000 0,25937868 0,28070165 ! coagulation GO:0050817 39 36 0,000 0,25937868 0,28053692 GO:0007596|blood coagulation, ! regulation of adenylate cyclase activity GO:0045761 37 37 0,000 0,26554692 0,28703986 GO:0031279|regulation of cyclase activity, GO:0051339|regulation of lyase activity, ! regulation of transcription factor activity GO:0051090 38 37 0,000 0,26554692 0,28687161 GO:0090046|regulation of transcription regulator activity, ! lung development GO:0030324 38 37 0,000 0,26554692 0,28670356 ! lymphocyte mediated immunity GO:0002449 37 37 0,000 0,26554692 0,2865357 ! eye development GO:0001654 37 37 0,000 0,26554692 0,28636803 ! ATP synthesis coupled electron transport GO:0042773 37 37 0,000 0,26554692 0,28620057 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! cellular amino acid catabolic process GO:0009063 38 37 0,000 0,26554692 0,2860333 ! regulation of Rho protein signal transduction GO:0035023 37 37 0,000 0,26554692 0,28586622 ! adaptive immune response GO:0002250 37 37 0,000 0,26554692 0,28569934 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! positive regulation of secretion GO:0051047 39 38 0,000 0,27166468 0,29211085 ! neurotransmitter transport GO:0006836 40 38 0,000 0,27166468 0,29194052 ! cellular hormone metabolic process GO:0034754 39 38 0,000 0,27166468 0,2917704 ! exocytosis GO:0006887 40 38 0,000 0,27166468 0,29160047 ! cell-matrix adhesion GO:0007160 39 38 0,000 0,27166468 0,29143073 ! urogenital system development GO:0001655 38 38 0,000 0,27166468 0,2912612 ! hexose catabolic process GO:0019320 38 38 0,000 0,27166468 0,29109186 ! RNA elongation GO:0006354 38 38 0,000 0,27166468 0,29092272 ! regulation of neurological system process GO:0031644 38 38 0,000 0,27166468 0,29075377 ! steroid hormone receptor signaling pathway GO:0030518 38 38 0,000 0,27166468 0,29058503 ! regulation of cAMP biosynthetic process GO:0030817 39 39 0,000 0,27773236 0,29690298 ! hemostasis GO:0007599 42 39 0,000 0,27773236 0,29673087 ! respiratory tube development GO:0030323 40 39 0,000 0,27773236 0,29655895 ! nucleoside monophosphate metabolic process GO:0009123 39 39 0,000 0,27773236 0,29638723 ! fatty acid biosynthetic process GO:0006633 39 39 0,000 0,27773236 0,29621571 ! cytokine-mediated signaling pathway GO:0019221 39 39 0,000 0,27773236 0,29604439 ! intracellular protein transmembrane transport GO:0065002 39 39 0,000 0,27773236 0,29587326 ! respiratory system development GO:0060541 40 39 0,000 0,27773236 0,29570234 ! developmental maturation GO:0021700 39 39 0,000 0,27773236 0,29553161 ! limb development GO:0060173 39 39 0,000 0,27773236 0,29536108 GO:0048736|appendage development, GO:0035107|appendage morphogenesis, ! regulation of cAMP metabolic process GO:0030814 40 40 0,000 0,28375038 0,30158705 ! DNA catabolic process GO:0006308 41 40 0,000 0,28375038 0,30141323 ! intracellular receptor-mediated signaling pathway GO:0030522 40 40 0,000 0,28375038 0,3012396 ! myeloid cell differentiation GO:0030099 42 40 0,000 0,28375038 0,30106618 ! organelle localization GO:0051640 41 40 0,000 0,28375038 0,30089295 ! regulation of nucleotide biosynthetic process GO:0030808 41 41 0,000 0,28971913 0,30704563 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! amine catabolic process GO:0009310 42 41 0,000 0,28971913 0,30686917 ! phospholipid biosynthetic process GO:0008654 42 41 0,000 0,28971913 0,30669291 ! leukocyte mediated immunity GO:0002443 41 41 0,000 0,28971913 0,30651685 ! regulation of Ras GTPase activity GO:0032318 41 41 0,000 0,28971913 0,30634099 ! monosaccharide catabolic process GO:0046365 41 41 0,000 0,28971913 0,30616534 ! respiratory electron transport chain GO:0022904 43 42 0,000 0,295639 0,31224222 ! regulation of cyclic nucleotide metabolic process GO:0030799 42 42 0,000 0,295639 0,31206339 ! cell-substrate adhesion GO:0031589 43 42 0,000 0,295639 0,31188476 ! development of primary sexual characteristics GO:0045137 42 42 0,000 0,295639 0,31170634 ! forebrain development GO:0030900 43 42 0,000 0,295639 0,31152812 ! reproductive structure development GO:0048608 43 43 0,000 0,30151039 0,31753352 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 43 43 0,000 0,30151039 0,31735217 ! alcohol catabolic process GO:0046164 43 43 0,000 0,30151039 0,31717103 ! homeostasis of number of cells GO:0048872 44 43 0,000 0,30151039 0,3169901 ! regulation of nucleotide metabolic process GO:0006140 43 43 0,000 0,30151039 0,31680938 ! humoral immune response GO:0006959 44 44 0,000 0,30733369 0,32274416 ! mRNA transport GO:0051028 44 44 0,000 0,30733369 0,32256036 ! negative regulation of organelle organization GO:0010639 45 44 0,000 0,30733369 0,32237678 ! vitamin metabolic process GO:0006766 44 44 0,000 0,30733369 0,3221934 ! amine biosynthetic process GO:0009309 46 45 0,000 0,31310929 0,32806164 ! regulation of DNA binding GO:0051101 47 45 0,000 0,31310929 0,32787524 ! steroid biosynthetic process GO:0006694 46 45 0,000 0,31310929 0,32768905 ! cyclic-nucleotide-mediated signaling GO:0019935 46 46 0,000 0,31883757 0,33349468 ! transcription initiation from RNA polymerase II promoter GO:0006367 46 46 0,000 0,31883757 0,33330552 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 47 47 0,000 0,3245189 0,33905235 ! regulation of blood pressure GO:0008217 48 47 0,000 0,3245189 0,33886025 ! sex differentiation GO:0007548 47 47 0,000 0,3245189 0,33866837 ! amine transport GO:0015837 47 47 0,000 0,3245189 0,33847671 ! rhythmic process GO:0048511 47 47 0,000 0,3245189 0,33828526 ! glycerophospholipid metabolic process GO:0006650 49 48 0,000 0,33015368 0,34396452 ! DNA recombination GO:0006310 48 48 0,000 0,33015368 0,34377019 ! ossification GO:0001503 50 49 0,000 0,33574227 0,34939187 GO:0060348|bone development, ! cellular lipid catabolic process GO:0044242 50 49 0,000 0,33574227 0,3491947 ! response to nutrient GO:0007584 49 49 0,000 0,33574227 0,34899774 ! response to bacterium GO:0009617 50 49 0,000 0,33574227 0,34880101 ! cofactor biosynthetic process GO:0051188 49 49 0,000 0,33574227 0,34860451 ! regulation of defense response GO:0031347 50 50 0,000 0,34128504 0,3541601 ! chromatin assembly GO:0031497 50 50 0,000 0,34128504 0,35396079 GO:0006334|nucleosome assembly, ! RNA transport GO:0050658 50 50 0,000 0,34128504 0,35376172 GO:0050657|nucleic acid transport, GO:0051236|establishment of RNA localization, ! nitrogen compound catabolic process GO:0044270 51 50 0,000 0,34128504 0,35356286 ! transcription initiation GO:0006352 50 50 0,000 0,34128504 0,35336423 ! anterior/posterior pattern formation GO:0009952 51 50 0,000 0,34128504 0,35316582 ! biogenic amine metabolic process GO:0006576 52 51 0,000 0,34678237 0,35865315 ! rRNA metabolic process GO:0016072 51 51 0,000 0,34678237 0,358452 GO:0006364|rRNA processing, ! protein-DNA complex assembly GO:0065004 51 51 0,000 0,34678237 0,35825107 ! RNA localization GO:0006403 52 52 0,000 0,35223462 0,36367978 ! cholesterol metabolic process GO:0008203 52 52 0,000 0,35223462 0,36347615 ! regulation of body fluid levels GO:0050878 55 52 0,000 0,35223462 0,36327275 ! sodium ion transport GO:0006814 53 53 0,000 0,35764215 0,36864345 ! tRNA metabolic process GO:0006399 53 53 0,000 0,35764215 0,36843739 ! response to hypoxia GO:0001666 53 53 0,000 0,35764215 0,36823156 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 53 53 0,000 0,35764215 0,36802595 ! carbohydrate biosynthetic process GO:0016051 53 53 0,000 0,35764215 0,36782058 ! carbohydrate catabolic process GO:0016052 53 53 0,000 0,35764215 0,36761544 ! response to oxygen levels GO:0070482 55 54 0,000 0,36300533 0,37292019 ! hormone metabolic process GO:0042445 55 54 0,000 0,36300533 0,37271243 ! negative regulation of multicellular organismal process GO:0051241 55 54 0,000 0,36300533 0,37250491 ! nucleosome organization GO:0034728 55 55 0,000 0,3683245 0,37775295 ! reproductive developmental process GO:0003006 56 56 0,000 0,37360003 0,38295042 ! regulation of binding GO:0051098 60 57 0,000 0,37883227 0,38809776 ! innate immune response GO:0045087 58 58 0,000 0,38402157 0,39319542 ! carboxylic acid transport GO:0046942 59 59 0,000 0,38916827 0,39824382 GO:0015849|organic acid transport, ! sterol metabolic process GO:0016125 59 59 0,000 0,38916827 0,39802282 ! cellular aromatic compound metabolic process GO:0006725 60 59 0,000 0,38916827 0,39780206 ! potassium ion transport GO:0006813 60 60 0,000 0,39427271 0,40279634 ! cellular respiration GO:0045333 62 61 0,000 0,39933524 0,4077423 ! carboxylic acid catabolic process GO:0046395 63 61 0,000 0,39933524 0,40751653 GO:0016054|organic acid catabolic process, ! lipid transport GO:0006869 62 62 0,000 0,40435619 0,41241199 ! regulation of cellular component biogenesis GO:0044087 63 62 0,000 0,40435619 0,41218389 ! regulation of secretion GO:0051046 65 63 0,000 0,40933591 0,41702934 ! negative regulation of cellular component organization GO:0051129 65 63 0,000 0,40933591 0,41679894 ! glucose metabolic process GO:0006006 63 63 0,000 0,40933591 0,41656879 ! glycerolipid metabolic process GO:0046486 65 64 0,000 0,41427472 0,4213622 ! regulation of response to external stimulus GO:0032101 65 64 0,000 0,41427472 0,42112979 ! angiogenesis GO:0001525 65 64 0,000 0,41427472 0,42089763 ! anion transport GO:0006820 65 65 0,000 0,41917295 0,42563953 ! regulation of hormone levels GO:0010817 66 65 0,000 0,41917295 0,42540514 ! protein amino acid glycosylation GO:0006486 66 66 0,000 0,42403093 0,43009851 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! DNA packaging GO:0006323 66 66 0,000 0,42403093 0,42986194 ! polysaccharide metabolic process GO:0005976 69 66 0,000 0,42403093 0,42962562 ! chromatin assembly or disassembly GO:0006333 68 68 0,000 0,43362744 0,43910735 ! regionalization GO:0003002 70 69 0,000 0,43836661 0,44366264 ! positive regulation of transport GO:0051050 71 70 0,000 0,44306682 0,44817351 ! growth GO:0040007 70 70 0,000 0,44306682 0,44792767 ! carboxylic acid biosynthetic process GO:0046394 70 70 0,000 0,44306682 0,4476821 GO:0016053|organic acid biosynthetic process, ! translational elongation GO:0006414 71 71 0,000 0,44772837 0,45214432 ! ribosome biogenesis GO:0042254 71 71 0,000 0,44772837 0,45189671 ! secretion by cell GO:0032940 75 72 0,000 0,45235159 0,45631307 ! sensory organ development GO:0007423 72 72 0,000 0,45235159 0,45606345 ! regulation of cytokine production GO:0001817 72 72 0,000 0,45235159 0,45581409 ! electron transport chain GO:0022900 75 74 0,000 0,46148424 0,46476255 ! glycoprotein biosynthetic process GO:0009101 80 80 0,000 0,48799379 0,491192 ! lipid catabolic process GO:0016042 82 81 0,000 0,49228561 0,49524147 ! ncRNA processing GO:0034470 83 83 0,000 0,50076348 0,50349541 ! organophosphate metabolic process GO:0019637 87 86 0,000 0,51322013 0,51573866 GO:0006644|phospholipid metabolic process, ! hexose metabolic process GO:0019318 87 86 0,000 0,51322013 0,51545761 ! chemotaxis GO:0006935 90 89 0,000 0,5253713 0,52737435 GO:0042330|taxis, ! regulation of Ras protein signal transduction GO:0046578 90 90 0,000 0,52935508 0,53108405 ! brain development GO:0007420 91 90 0,000 0,52935508 0,53079511 ! energy derivation by oxidation of organic compounds GO:0015980 94 92 0,000 0,53722433 0,53839284 ! regulation of response to stress GO:0080134 97 94 0,000 0,54496428 0,54585281 ! pattern specification process GO:0007389 96 94 0,000 0,54496428 0,54555631 ! blood circulation GO:0008015 99 98 0,000 0,56006458 0,56036863 GO:0003013|circulatory system process, ! regulation of system process GO:0044057 98 98 0,000 0,56006458 0,56006458