pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6763-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! release of cytochrome c from mitochondria GO:0001836 30 14 3,000 8,535E-07 2,053E-03 ! male meiosis GO:0007140 7 6 2,000 3,249E-06 3,909E-03 ! apoptotic mitochondrial changes GO:0008637 41 20 3,000 4,026E-06 3,228E-03 ! induction of apoptosis by intracellular signals GO:0008629 93 45 4,000 4,895E-06 2,945E-03 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 2,000 9,024E-06 4,342E-03 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 3,000 1,029E-05 4,125E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 2,000 1,348E-05 4,634E-03 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 2,000 1,918E-05 5,769E-03 ! protein sumoylation GO:0016925 15 10 2,000 1,918E-05 5,128E-03 ! cell cycle arrest GO:0007050 213 100 5,000 1,99E-05 4,788E-03 ! negative regulation of protein kinase activity GO:0006469 130 67 4,000 3,509E-05 7,676E-03 ! negative regulation of kinase activity GO:0033673 131 68 4,000 3,771E-05 7,561E-03 ! response to X-ray GO:0010165 25 13 2,000 4,516E-05 8,358E-03 ! negative regulation of transferase activity GO:0051348 140 72 4,000 4,973E-05 8,546E-03 ! regulation of S phase GO:0033261 23 14 2,000 5,724E-05 9,182E-03 ! response to gamma radiation GO:0010332 28 14 2,000 5,724E-05 8,608E-03 ! mammary gland development GO:0030879 86 39 3,000 6,298E-05 8,914E-03 ! centrosome cycle GO:0007098 25 18 2,000 1,263E-04 0,01687732 ! synapse organization GO:0050808 85 52 3,000 1,961E-04 0,02482857 ! glycerol metabolic process GO:0006071 34 21 2,000 2,033E-04 0,02445843 ! cell aging GO:0007569 44 21 2,000 2,033E-04 0,02329374 ! regulation of DNA metabolic process GO:0051052 178 97 4,000 2,05E-04 0,02242404 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 2,000 2,345E-04 0,02452681 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 3,000 2,8E-04 0,02807254 ! 2-oxoglutarate metabolic process GO:0006103 7 5 1,000 2,987E-04 0,02874762 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 1,000 2,987E-04 0,02764194 ! Notch receptor processing GO:0007220 8 5 1,000 2,987E-04 0,02661817 ! negative regulation of survival gene product expression GO:0008634 8 5 1,000 2,987E-04 0,02566752 ! valine metabolic process GO:0006573 10 5 1,000 2,987E-04 0,02478243 ! polyol catabolic process GO:0046174 7 5 1,000 2,987E-04 0,02395635 GO:0019405|alditol catabolic process, ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 1,000 2,987E-04 0,02318357 ! negative regulation of T cell mediated immunity GO:0002710 12 5 1,000 2,987E-04 0,02245908 GO:0002707|negative regulation of lymphocyte mediated immunity, ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 1,000 2,987E-04 0,0217785 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 1,000 2,987E-04 0,02113796 ! inner cell mass cell proliferation GO:0001833 5 5 1,000 2,987E-04 0,02053402 ! neural plate development GO:0001840 8 5 1,000 2,987E-04 0,01996363 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 1,000 2,987E-04 0,01942407 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of phosphorylation GO:0042326 47 24 2,000 3,057E-04 0,01935347 ! alditol metabolic process GO:0019400 38 24 2,000 3,057E-04 0,01885723 ! DNA damage response, signal transduction GO:0042770 128 60 3,000 3,413E-04 0,02052808 ! negative regulation of DNA replication GO:0008156 42 25 2,000 3,459E-04 0,02030105 ! regulation of homeostatic process GO:0032844 134 62 3,000 3,871E-04 0,02217506 ! microtubule organizing center organization GO:0031023 39 26 2,000 3,895E-04 0,02179328 GO:0051297|centrosome organization, ! negative regulation of phosphorus metabolic process GO:0010563 51 26 2,000 3,895E-04 0,02129798 GO:0045936|negative regulation of phosphate metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 1,000 4,464E-04 0,02386949 ! activation of MAPKKK activity GO:0000185 12 6 1,000 4,464E-04 0,02335059 ! thymic T cell selection GO:0045061 12 6 1,000 4,464E-04 0,02285377 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 1,000 4,464E-04 0,02237765 ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 1,000 4,464E-04 0,02192096 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! response to UV-C GO:0010225 11 6 1,000 4,464E-04 0,02148254 ! negative regulation of neuroblast proliferation GO:0007406 21 6 1,000 4,464E-04 0,02106131 ! regulation of helicase activity GO:0051095 15 7 1,000 6,227E-04 0,028814 ! cytokinesis during cell cycle GO:0033205 11 7 1,000 6,227E-04 0,02827034 ! regulation of lipid kinase activity GO:0043550 13 7 1,000 6,227E-04 0,02774681 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 6,227E-04 0,02724232 ! oxaloacetate metabolic process GO:0006107 10 7 1,000 6,227E-04 0,02675585 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 1,000 6,227E-04 0,02628645 ! amyloid precursor protein catabolic process GO:0042987 11 7 1,000 6,227E-04 0,02583324 ! positive regulation of isotype switching GO:0045830 15 7 1,000 6,227E-04 0,02539539 GO:0045911|positive regulation of DNA recombination, ! vesicle fusion GO:0006906 17 7 1,000 6,227E-04 0,02497213 ! positive regulation of mitotic cell cycle GO:0045931 12 7 1,000 6,227E-04 0,02456275 ! centrosome duplication GO:0051298 13 7 1,000 6,227E-04 0,02416658 ! G1 DNA damage checkpoint GO:0031571 21 7 1,000 6,227E-04 0,02378298 ! anterograde axon cargo transport GO:0008089 18 7 1,000 6,227E-04 0,02341137 ! B cell lineage commitment GO:0002326 21 7 1,000 6,227E-04 0,0230512 ! T cell lineage commitment GO:0002360 16 7 1,000 6,227E-04 0,02270194 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 1,000 6,227E-04 0,0223631 GO:0002714|positive regulation of B cell mediated immunity, ! response to tumor cell GO:0002347 13 7 1,000 6,227E-04 0,02203423 ! coenzyme A metabolic process GO:0015936 12 7 1,000 6,227E-04 0,0217149 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 1,000 6,227E-04 0,02140468 ! regulation of caspase activity GO:0043281 122 72 3,000 6,84E-04 0,02318053 ! axon guidance GO:0007411 139 73 3,000 7,206E-04 0,02408076 ! response to ionizing radiation GO:0010212 65 32 2,000 7,252E-04 0,02390254 ! regulation of endopeptidase activity GO:0052548 125 74 3,000 7,586E-04 0,02466335 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 1,000 8,273E-04 0,02654044 ! succinate metabolic process GO:0006105 14 8 1,000 8,273E-04 0,02619122 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 1,000 8,273E-04 0,02585108 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 8,273E-04 0,02551965 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 1,000 8,273E-04 0,02519662 ! ER overload response GO:0006983 12 8 1,000 8,273E-04 0,02488166 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 1,000 8,273E-04 0,02457448 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 1,000 8,273E-04 0,02427479 ! ATP catabolic process GO:0006200 11 8 1,000 8,273E-04 0,02398233 ! blastocyst growth GO:0001832 19 8 1,000 8,273E-04 0,02369682 ! B cell receptor signaling pathway GO:0050853 16 8 1,000 8,273E-04 0,02341804 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 1,000 8,273E-04 0,02314573 ! negative regulation of DNA metabolic process GO:0051053 61 35 2,000 9,455E-04 0,02614661 ! negative regulation of hydrolase activity GO:0051346 62 35 2,000 9,455E-04 0,02584949 ! regulation of peptidase activity GO:0052547 134 79 3,000 9,696E-04 0,02621297 ! keratinocyte proliferation GO:0043616 14 9 1,000 1,06E-03 0,02833322 ! middle ear morphogenesis GO:0042474 14 9 1,000 1,06E-03 0,02802186 ! amyloid precursor protein metabolic process GO:0042982 14 9 1,000 1,06E-03 0,02771728 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 1,000 1,06E-03 0,02741924 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 1,000 1,06E-03 0,02712755 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! T cell selection GO:0045058 23 9 1,000 1,06E-03 0,02684199 ! phosphagen metabolic process GO:0006599 12 9 1,000 1,06E-03 0,02656239 GO:0006600|creatine metabolic process, ! motor axon guidance GO:0008045 16 9 1,000 1,06E-03 0,02628855 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 1,000 1,06E-03 0,0260203 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 1,000 1,06E-03 0,02575747 GO:0002820|negative regulation of adaptive immune response, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 1,000 1,06E-03 0,02549989 ! regulation of telomere maintenance GO:0032204 14 9 1,000 1,06E-03 0,02524742 ! cellular response to hormone stimulus GO:0032870 167 82 3,000 1,114E-03 0,02628724 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 1,32E-03 0,03083446 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 1,000 1,32E-03 0,03053798 ! multicellular organism growth GO:0035264 18 10 1,000 1,32E-03 0,03024714 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 1,000 1,32E-03 0,02996179 ! regulation of B cell differentiation GO:0045577 19 10 1,000 1,32E-03 0,02968177 ! apical protein localization GO:0045176 15 10 1,000 1,32E-03 0,02940694 ! oocyte development GO:0048599 17 10 1,000 1,32E-03 0,02913715 ! establishment of cell polarity GO:0030010 16 10 1,000 1,32E-03 0,02887227 ! negative regulation of immune effector process GO:0002698 20 10 1,000 1,32E-03 0,02861216 ! mitochondrion organization GO:0007005 148 86 3,000 1,33E-03 0,02857518 ! cytokinesis GO:0000910 72 40 2,000 1,399E-03 0,02978142 ! gland development GO:0048732 206 88 3,000 1,448E-03 0,0305668 ! regulation of T cell proliferation GO:0042129 71 41 2,000 1,503E-03 0,03144677 ! T cell differentiation GO:0030217 81 41 2,000 1,503E-03 0,03117568 ! regulation of T cell differentiation GO:0045580 70 41 2,000 1,503E-03 0,03090922 ! polyol metabolic process GO:0019751 66 41 2,000 1,503E-03 0,03064728 ! detection of mechanical stimulus GO:0050982 22 11 1,000 1,608E-03 0,03250145 ! T cell proliferation GO:0042098 26 11 1,000 1,608E-03 0,0322306 ! negative regulation of proteolysis GO:0045861 25 11 1,000 1,608E-03 0,03196423 ! regulation of intracellular pH GO:0051453 19 11 1,000 1,608E-03 0,03170223 ! positive regulation of T cell mediated immunity GO:0002711 24 11 1,000 1,608E-03 0,03144449 ! purine ribonucleotide catabolic process GO:0009154 17 11 1,000 1,608E-03 0,0311909 ! nitric oxide metabolic process GO:0046209 15 11 1,000 1,608E-03 0,03094138 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 1,000 1,608E-03 0,03069581 GO:0006305|DNA alkylation, ! regulation of isotype switching GO:0045191 22 11 1,000 1,608E-03 0,03045411 ! oocyte differentiation GO:0009994 18 11 1,000 1,608E-03 0,03021619 ! lysogeny GO:0030069 21 11 1,000 1,608E-03 0,02998195 GO:0019047|provirus integration, ! T cell receptor signaling pathway GO:0050852 23 11 1,000 1,608E-03 0,02975132 ! regulation of embryonic development GO:0045995 27 11 1,000 1,608E-03 0,02952421 ! regulation of epithelial cell proliferation GO:0050678 111 43 2,000 1,726E-03 0,03146256 ! positive regulation of MAP kinase activity GO:0043406 160 93 3,000 1,775E-03 0,03211461 ! double-strand break repair GO:0006302 81 44 2,000 1,845E-03 0,03312707 ! JAK-STAT cascade GO:0007259 71 44 2,000 1,845E-03 0,03288169 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 1,000 1,922E-03 0,0340031 ! regulation of B cell proliferation GO:0030888 20 12 1,000 1,922E-03 0,03375491 ! positive regulation of cell growth GO:0030307 22 12 1,000 1,922E-03 0,0335103 ! oligodendrocyte differentiation GO:0048709 16 12 1,000 1,922E-03 0,03326922 ! asymmetric protein localization GO:0008105 20 12 1,000 1,922E-03 0,03303159 ! membrane protein proteolysis GO:0033619 25 12 1,000 1,922E-03 0,03279732 GO:0006509|membrane protein ectodomain proteolysis, ! negative regulation of mast cell proliferation GO:0070667 23 12 1,000 1,922E-03 0,03256635 GO:0042130|negative regulation of T cell proliferation, ! detection of stimulus involved in sensory perception GO:0050906 66 45 2,000 1,969E-03 0,03312582 ! protein ubiquitination GO:0016567 217 97 3,000 2,071E-03 0,03460576 ! pigmentation GO:0043473 100 46 2,000 2,098E-03 0,03480776 ! double-strand break repair via homologous recombination GO:0000724 19 13 1,000 2,263E-03 0,03729774 GO:0000725|recombinational repair, ! organelle fusion GO:0048284 32 13 1,000 2,263E-03 0,03704401 ! ribonucleotide catabolic process GO:0009261 20 13 1,000 2,263E-03 0,03679372 ! cellular carbohydrate catabolic process GO:0044275 15 13 1,000 2,263E-03 0,03654678 ! nucleoside triphosphate catabolic process GO:0009143 21 13 1,000 2,263E-03 0,03630313 ! regulation of cellular pH GO:0030641 22 13 1,000 2,263E-03 0,03606272 ! actin filament polymerization GO:0030041 24 13 1,000 2,263E-03 0,03582546 ! Notch signaling pathway GO:0007219 96 48 2,000 2,371E-03 0,03728481 ! activation of caspase activity GO:0006919 84 48 2,000 2,371E-03 0,0370427 ! regulation of lymphocyte differentiation GO:0045619 81 48 2,000 2,371E-03 0,03680372 ! regulation of mast cell proliferation GO:0070666 81 48 2,000 2,371E-03 0,03656779 ! detection of abiotic stimulus GO:0009582 74 49 2,000 2,515E-03 0,0385492 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 1,000 2,631E-03 0,04006388 ! regulation of mRNA processing GO:0050684 24 14 1,000 2,631E-03 0,03981191 ! negative regulation of caspase activity GO:0043154 22 14 1,000 2,631E-03 0,03956308 ! bone mineralization GO:0030282 17 14 1,000 2,631E-03 0,03931735 ! T cell differentiation in the thymus GO:0033077 31 14 1,000 2,631E-03 0,03907465 ! regulation of erythrocyte differentiation GO:0045646 44 14 1,000 2,631E-03 0,03883493 ! negative regulation of immune system process GO:0002683 95 50 2,000 2,665E-03 0,03910184 ! response to estrogen stimulus GO:0043627 93 51 2,000 2,821E-03 0,04112826 ! regulation of leukocyte proliferation GO:0070663 88 51 2,000 2,821E-03 0,04088049 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! positive regulation of growth GO:0045927 90 52 2,000 2,981E-03 0,04295065 ! positive regulation of cell size GO:0045793 27 15 1,000 3,025E-03 0,04331889 ! heterophilic cell adhesion GO:0007157 39 15 1,000 3,025E-03 0,04306257 ! glycoprotein catabolic process GO:0006516 26 15 1,000 3,025E-03 0,04280926 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 1,000 3,025E-03 0,04255891 ! G1/S transition checkpoint GO:0031575 40 15 1,000 3,025E-03 0,04231148 ! regulation of T cell mediated immunity GO:0002709 33 15 1,000 3,025E-03 0,0420669 ! synaptic transmission, cholinergic GO:0007271 24 15 1,000 3,025E-03 0,04182514 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 2,000 3,147E-03 0,04327223 ! response to UV GO:0009411 104 53 2,000 3,147E-03 0,04302637 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 1,000 3,444E-03 0,04682035 ! activation of MAPKK activity GO:0000186 35 16 1,000 3,444E-03 0,04655731 ! intermediate filament-based process GO:0045103 32 16 1,000 3,444E-03 0,04629722 ! negative regulation of immune response GO:0050777 35 16 1,000 3,444E-03 0,04604001 ! axon cargo transport GO:0008088 43 16 1,000 3,444E-03 0,04578565 ! biomineral formation GO:0031214 20 16 1,000 3,444E-03 0,04553408 ! neuromuscular synaptic transmission GO:0007274 33 16 1,000 3,444E-03 0,04528526 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 1,000 3,444E-03 0,04503914 ! negative regulation of leukocyte proliferation GO:0070664 31 16 1,000 3,444E-03 0,04479569 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 3,444E-03 0,04455485 ! defense response to virus GO:0051607 37 16 1,000 3,444E-03 0,04431659 ! positive regulation of caspase activity GO:0043280 95 55 2,000 3,497E-03 0,04474909 GO:0010952|positive regulation of peptidase activity, ! regulation of protein catabolic process GO:0042176 116 55 2,000 3,497E-03 0,04451232 ! aging GO:0007568 103 55 2,000 3,497E-03 0,04427805 ! regulation of actin filament length GO:0030832 105 56 2,000 3,68E-03 0,04635296 ! nucleotide-excision repair GO:0006289 83 56 2,000 3,68E-03 0,04611154 ! regulation of DNA replication GO:0006275 101 56 2,000 3,68E-03 0,04587262 ! positive regulation of cell killing GO:0031343 32 17 1,000 3,89E-03 0,04823851 ! negative regulation of peptidase activity GO:0010466 27 17 1,000 3,89E-03 0,04799113 ! regulation of survival gene product expression GO:0045884 33 17 1,000 3,89E-03 0,04774628 ! DNA integration GO:0015074 29 17 1,000 3,89E-03 0,04750391 ! negative regulation of protein catabolic process GO:0042177 40 17 1,000 3,89E-03 0,04726399 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 1,000 3,89E-03 0,04702648 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 1,000 3,89E-03 0,04679135 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 1,000 3,89E-03 0,04655856 ! branched chain family amino acid metabolic process GO:0009081 33 17 1,000 3,89E-03 0,04632807 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 1,000 3,89E-03 0,04609985 ! regulation of cellular component size GO:0032535 109 59 2,000 4,264E-03 0,05028791 ! regulation of immunoglobulin production GO:0002637 43 18 1,000 4,36E-03 0,05117112 ! skin development GO:0043588 36 19 1,000 4,855E-03 0,05670843 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 1,000 4,855E-03 0,05643448 ! neuromuscular junction development GO:0007528 34 19 1,000 4,855E-03 0,05616316 ! cellular pigmentation GO:0033059 36 19 1,000 4,855E-03 0,05589444 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 1,000 4,855E-03 0,05562827 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 1,000 4,855E-03 0,05536463 ! purine nucleotide catabolic process GO:0006195 29 19 1,000 4,855E-03 0,05510348 ! detection of external stimulus GO:0009581 91 63 2,000 5,126E-03 0,05789724 ! response to alkaloid GO:0043279 38 20 1,000 5,375E-03 0,0604353 ! cellular response to starvation GO:0009267 33 20 1,000 5,375E-03 0,0601542 ! actin polymerization or depolymerization GO:0008154 48 20 1,000 5,375E-03 0,05987571 ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 1,000 5,375E-03 0,05959979 ! negative regulation of T cell activation GO:0050868 40 20 1,000 5,375E-03 0,05932639 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 1,000 5,375E-03 0,0590555 ! actin filament organization GO:0007015 148 66 2,000 5,836E-03 0,06382227 ! regulation of cell killing GO:0031341 42 21 1,000 5,92E-03 0,06444818 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 1,000 5,92E-03 0,06415787 ! cell structure disassembly during apoptosis GO:0006921 30 21 1,000 5,92E-03 0,06387017 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 1,000 5,92E-03 0,06358503 ! oogenesis GO:0048477 36 21 1,000 5,92E-03 0,06330243 ! DNA modification GO:0006304 34 21 1,000 5,92E-03 0,06302233 ! negative regulation of intracellular transport GO:0032387 41 21 1,000 5,92E-03 0,0627447 ! negative regulation of cell growth GO:0030308 132 67 2,000 6,085E-03 0,06421206 ! activation of MAPK activity GO:0000187 115 67 2,000 6,085E-03 0,06393166 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 2,000 6,085E-03 0,06365369 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 2,000 6,085E-03 0,06337814 ! negative regulation of ligase activity GO:0051352 112 68 2,000 6,34E-03 0,06575385 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 2,000 6,34E-03 0,06547164 ! positive regulation of protein catabolic process GO:0045732 38 22 1,000 6,488E-03 0,06671342 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 1,000 6,488E-03 0,06642953 ! microtubule-based transport GO:0010970 54 22 1,000 6,488E-03 0,06614805 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 1,000 6,488E-03 0,06586894 ! cellular response to reactive oxygen species GO:0034614 31 22 1,000 6,488E-03 0,06559218 ! positive regulation of cytoskeleton organization GO:0051495 48 22 1,000 6,488E-03 0,06531774 ! apoptotic nuclear changes GO:0030262 32 22 1,000 6,488E-03 0,06504558 ! positive regulation of adaptive immune response GO:0002821 39 22 1,000 6,488E-03 0,06477568 ! sarcomere organization GO:0045214 30 22 1,000 6,488E-03 0,06450802 ! positive regulation of B cell activation GO:0050871 38 22 1,000 6,488E-03 0,06424255 ! negative regulation of cell size GO:0045792 134 69 2,000 6,602E-03 0,06510091 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 2,000 6,602E-03 0,0648352 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 1,000 7,081E-03 0,06925269 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 7,081E-03 0,06897231 ! gluconeogenesis GO:0006094 33 23 1,000 7,081E-03 0,0686942 ! leukocyte adhesion GO:0007159 50 23 1,000 7,081E-03 0,06841832 ! regulation of DNA recombination GO:0000018 48 23 1,000 7,081E-03 0,06814465 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 1,000 7,081E-03 0,06787315 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 1,000 7,081E-03 0,06760382 ! purine ribonucleoside metabolic process GO:0046128 34 23 1,000 7,081E-03 0,06733661 GO:0042278|purine nucleoside metabolic process, ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 1,000 7,081E-03 0,0670715 ! negative regulation of catabolic process GO:0009895 50 23 1,000 7,081E-03 0,06680848 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 2,000 7,426E-03 0,06978847 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 2,000 7,426E-03 0,06951692 ! protein import into nucleus, translocation GO:0000060 46 24 1,000 7,697E-03 0,07177537 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 1,000 7,697E-03 0,07149825 ! regulation of alpha-beta T cell activation GO:0046634 42 24 1,000 7,697E-03 0,07122325 ! lymphocyte proliferation GO:0046651 48 24 1,000 7,697E-03 0,07095037 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 1,000 7,697E-03 0,07067957 GO:0002708|positive regulation of lymphocyte mediated immunity, ! protein tetramerization GO:0051262 52 24 1,000 7,697E-03 0,07041082 ! meiosis GO:0007126 121 74 2,000 8,007E-03 0,0729705 GO:0051327|M phase of meiotic cell cycle, ! regulation of actin cytoskeleton organization GO:0032956 149 74 2,000 8,007E-03 0,07269514 ! meiotic cell cycle GO:0051321 122 75 2,000 8,307E-03 0,07513872 ! lymphocyte differentiation GO:0030098 167 75 2,000 8,307E-03 0,0748573 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 1,000 8,336E-03 0,07483557 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 1,000 8,336E-03 0,07455737 ! myelination GO:0042552 45 25 1,000 8,336E-03 0,07428123 ! dicarboxylic acid metabolic process GO:0043648 42 25 1,000 8,336E-03 0,07400713 ! phototransduction GO:0007602 33 25 1,000 8,336E-03 0,07373505 ! response to starvation GO:0042594 42 25 1,000 8,336E-03 0,07346496 ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 8,336E-03 0,07319684 ! neural crest cell development GO:0014032 54 25 1,000 8,336E-03 0,07293067 GO:0014033|neural crest cell differentiation, ! negative regulation of cell development GO:0010721 73 25 1,000 8,336E-03 0,07266642 GO:0050768|negative regulation of neurogenesis, ! immunoglobulin production GO:0002377 55 25 1,000 8,336E-03 0,07240409 GO:0002440|production of molecular mediator of immune response, ! cellular response to nutrient levels GO:0031669 41 25 1,000 8,336E-03 0,07214364 ! regulation of catabolic process GO:0009894 161 76 2,000 8,614E-03 0,07428444 ! regulation of actin filament-based process GO:0032970 152 77 2,000 8,928E-03 0,07671308 ! positive regulation of ligase activity GO:0051351 124 77 2,000 8,928E-03 0,07644008 ! initiation of viral infection GO:0019059 57 26 1,000 8,998E-03 0,0767701 ! pyruvate metabolic process GO:0006090 38 26 1,000 8,998E-03 0,07649883 ! insulin receptor signaling pathway GO:0008286 64 26 1,000 8,998E-03 0,07622947 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 1,000 8,998E-03 0,07596199 ! cellular response to oxidative stress GO:0034599 39 26 1,000 8,998E-03 0,07569639 ! response to estradiol stimulus GO:0032355 40 26 1,000 8,998E-03 0,07543264 ! positive regulation of MAPKKK cascade GO:0043410 47 26 1,000 8,998E-03 0,07517072 ! group transfer coenzyme metabolic process GO:0006752 47 26 1,000 8,998E-03 0,07491062 ! blastocyst development GO:0001824 49 26 1,000 8,998E-03 0,07465231 ! leukocyte proliferation GO:0070661 52 26 1,000 8,998E-03 0,07439577 GO:0032943|mononuclear cell proliferation, ! response to steroid hormone stimulus GO:0048545 137 78 2,000 9,248E-03 0,07619821 ! activation of protein kinase activity GO:0032147 147 79 2,000 9,574E-03 0,0786214 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 2,000 9,574E-03 0,07835398 ! regulation of fibroblast proliferation GO:0048145 52 27 1,000 9,683E-03 0,07897323 ! neuron fate commitment GO:0048663 48 27 1,000 9,683E-03 0,07870643 ! mitochondrial membrane organization GO:0007006 57 27 1,000 9,683E-03 0,07844142 ! response to toxin GO:0009636 47 27 1,000 9,683E-03 0,0781782 ! primary neural tube formation GO:0014020 51 27 1,000 9,683E-03 0,07791673 ! base-excision repair GO:0006284 41 27 1,000 9,683E-03 0,07765701 ! regulation of chromosome organization GO:0033044 42 27 1,000 9,683E-03 0,07739901 ! negative regulation of neuron differentiation GO:0045665 42 27 1,000 9,683E-03 0,07714272 ! negative regulation of lymphocyte activation GO:0051250 53 27 1,000 9,683E-03 0,07688813 ! T cell activation GO:0042110 168 81 2,000 0,01024798 0,0811074 ! regulation of actin filament depolymerization GO:0030834 58 28 1,000 0,01039031 0,08196423 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 1,000 0,01039031 0,08169638 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! negative regulation of protein modification process GO:0031400 60 28 1,000 0,01039031 0,08143026 ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 0,01039031 0,08116588 ! positive regulation of T cell differentiation GO:0045582 42 28 1,000 0,01039031 0,08090321 ! synaptogenesis GO:0007416 42 28 1,000 0,01039031 0,08064223 ! peptidyl-tyrosine modification GO:0018212 50 28 1,000 0,01039031 0,08038293 ! response to drug GO:0042493 143 82 2,000 0,01059483 0,08170243 ! regulation of pH GO:0006885 43 29 1,000 0,01111991 0,08547762 ! cellular iron ion homeostasis GO:0006879 51 29 1,000 0,01111991 0,0852054 ! immune response-activating signal transduction GO:0002757 47 29 1,000 0,01111991 0,08493491 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 1,000 0,01111991 0,08466613 ! response to organic cyclic substance GO:0014070 55 29 1,000 0,01111991 0,08439904 ! detection of light stimulus GO:0009583 38 29 1,000 0,01111991 0,08413364 ! cellular response to extracellular stimulus GO:0031668 48 29 1,000 0,01111991 0,08386989 ! tissue homeostasis GO:0001894 48 29 1,000 0,01111991 0,0836078 GO:0048871|multicellular organismal homeostasis, ! negative regulation of growth GO:0045926 155 84 2,000 0,01130876 0,08476289 ! regulation of ligase activity GO:0051340 142 84 2,000 0,01130876 0,08449965 ! myofibril assembly GO:0030239 47 30 1,000 0,01187144 0,08842936 GO:0055002|striated muscle cell development, ! positive regulation of multicellular organism growth GO:0040018 51 30 1,000 0,01187144 0,08815643 ! ensheathment of neurons GO:0007272 57 30 1,000 0,01187144 0,08788518 GO:0008366|axon ensheathment, ! negative regulation of leukocyte activation GO:0002695 56 30 1,000 0,01187144 0,0876156 ! regulation of B cell activation GO:0050864 50 30 1,000 0,01187144 0,08734766 ! response to heat GO:0009408 50 30 1,000 0,01187144 0,08708136 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 1,000 0,01264465 0,09247121 ! positive regulation of T cell proliferation GO:0042102 52 31 1,000 0,01264465 0,09219099 ! iron ion homeostasis GO:0055072 54 31 1,000 0,01264465 0,09191247 ! positive regulation of immune effector process GO:0002699 67 31 1,000 0,01264465 0,09163563 ! regulation of cell adhesion GO:0030155 212 89 2,000 0,01321269 0,09546467 ! response to mechanical stimulus GO:0009612 57 32 1,000 0,01343928 0,09681109 ! muscle cell development GO:0055001 49 32 1,000 0,01343928 0,0965221 ! hexose biosynthetic process GO:0019319 48 32 1,000 0,01343928 0,09623483 ! peripheral nervous system development GO:0007422 64 32 1,000 0,01343928 0,09594927 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 1,000 0,01343928 0,0956654 ! positive regulation of catabolic process GO:0009896 64 32 1,000 0,01343928 0,0953832 ! regulation of cell cycle process GO:0010564 149 90 2,000 0,01361404 0,09633937 ! DNA damage checkpoint GO:0000077 71 33 1,000 0,01425507 0,10057975 ! positive regulation of gene-specific transcription GO:0043193 65 33 1,000 0,01425507 0,10028566 ! negative regulation of protein transport GO:0051224 69 33 1,000 0,01425507 0,09999328 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 2,000 0,01485951 0,10393017 GO:0010498|proteasomal protein catabolic process, ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 1,000 0,01509177 0,10524867 ! glial cell differentiation GO:0010001 63 34 1,000 0,01509177 0,10494448 ! xenobiotic metabolic process GO:0006805 51 34 1,000 0,01509177 0,10464205 ! regulation of T cell activation GO:0050863 158 94 2,000 0,01528852 0,10570164 ! interphase of mitotic cell cycle GO:0051329 209 95 2,000 0,01572447 0,10840423 ! female gonad development GO:0008585 58 35 1,000 0,01594912 0,1096388 ! neural tube formation GO:0001841 67 35 1,000 0,01594912 0,10932644 ! leukocyte differentiation GO:0002521 202 96 2,000 0,01616738 0,11050773 ! detection of stimulus GO:0051606 151 96 2,000 0,01616738 0,11019468 ! positive regulation of JAK-STAT cascade GO:0046427 50 36 1,000 0,01682688 0,11436572 ! maintenance of protein location in cell GO:0032507 86 36 1,000 0,01682688 0,11404356 ! DNA integrity checkpoint GO:0031570 75 36 1,000 0,01682688 0,11372321 ! regulation of proteolysis GO:0030162 72 36 1,000 0,01682688 0,11340466 ! monosaccharide biosynthetic process GO:0046364 52 36 1,000 0,01682688 0,11308789 ! negative regulation of cell activation GO:0050866 65 36 1,000 0,01682688 0,11277288 ! interphase GO:0051325 213 98 2,000 0,01707412 0,11411202 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 1,000 0,01772479 0,11813253 ! establishment or maintenance of cell polarity GO:0007163 83 37 1,000 0,01772479 0,1178062 ! actomyosin structure organization GO:0031032 62 37 1,000 0,01772479 0,11748166 ! monovalent inorganic cation homeostasis GO:0055067 58 37 1,000 0,01772479 0,11715891 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 1,000 0,01772479 0,11683793 GO:0015986|ATP synthesis coupled proton transport, ! cellular response to insulin stimulus GO:0032869 82 37 1,000 0,01772479 0,1165187 ! positive regulation of DNA metabolic process GO:0051054 72 38 1,000 0,01864261 0,12221834 ! mitotic cell cycle checkpoint GO:0007093 76 38 1,000 0,01864261 0,12188622 ! development of primary female sexual characteristics GO:0046545 67 38 1,000 0,01864261 0,12155591 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 1,000 0,01864261 0,12122738 ! nucleotide catabolic process GO:0009166 61 38 1,000 0,01864261 0,12090062 ! embryonic epithelial tube formation GO:0001838 72 38 1,000 0,01864261 0,12057562 ! positive regulation of leukocyte proliferation GO:0070665 62 38 1,000 0,01864261 0,12025236 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! learning GO:0007612 77 39 1,000 0,0195801 0,12596185 ! ear morphogenesis GO:0042471 60 39 1,000 0,0195801 0,12562595 ! ion transmembrane transport GO:0034220 66 39 1,000 0,0195801 0,12529184 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 1,000 0,0195801 0,1249595 ! regulation of action potential in neuron GO:0019228 73 39 1,000 0,0195801 0,12462892 ! Rho protein signal transduction GO:0007266 74 39 1,000 0,0195801 0,12430008 ! response to xenobiotic stimulus GO:0009410 57 39 1,000 0,0195801 0,12397298 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 1,000 0,02053702 0,12969047 ! multicellular organismal metabolic process GO:0044236 57 40 1,000 0,02053702 0,12935097 ! mesenchymal cell development GO:0014031 87 40 1,000 0,02053702 0,12901324 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 1,000 0,02053702 0,12867727 ! maintenance of protein location GO:0045185 91 40 1,000 0,02053702 0,12834304 ! cellular amide metabolic process GO:0043603 67 41 1,000 0,02151312 0,13409473 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 1,000 0,02151312 0,13374824 ! gliogenesis GO:0042063 88 41 1,000 0,02151312 0,13340352 ! keratinocyte differentiation GO:0030216 62 41 1,000 0,02151312 0,13306058 ! female gamete generation GO:0007292 61 41 1,000 0,02151312 0,1327194 ! response to reactive oxygen species GO:0000302 67 42 1,000 0,02250817 0,13850294 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 1,000 0,02250817 0,13814962 ! alcohol biosynthetic process GO:0046165 59 42 1,000 0,02250817 0,13779809 ! regulation of intracellular protein transport GO:0033157 80 42 1,000 0,02250817 0,13744835 ! regulation of leukocyte mediated immunity GO:0002703 79 42 1,000 0,02250817 0,13710038 ! regulation of myeloid cell differentiation GO:0045637 98 42 1,000 0,02250817 0,13675417 ! striated muscle cell differentiation GO:0051146 82 43 1,000 0,02352193 0,14255353 ! neural tube development GO:0021915 77 43 1,000 0,02352193 0,14219536 ! striated muscle contraction GO:0006941 77 43 1,000 0,02352193 0,14183898 ! biopolymer methylation GO:0043414 84 44 1,000 0,02455416 0,14769328 ! B cell differentiation GO:0030183 107 44 1,000 0,02455416 0,14732497 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 1,000 0,02455416 0,14695849 ! developmental growth GO:0048589 82 44 1,000 0,02455416 0,14659382 ! maintenance of location in cell GO:0051651 97 44 1,000 0,02455416 0,14623097 ! regulation of JAK-STAT cascade GO:0046425 70 45 1,000 0,02560464 0,15211054 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 1,000 0,02667314 0,15806791 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 1,000 0,02667314 0,15767953 ! regulation of gene-specific transcription GO:0032583 96 46 1,000 0,02667314 0,15729306 ! epidermal cell differentiation GO:0009913 68 46 1,000 0,02667314 0,15690848 ! response to insulin stimulus GO:0032868 95 46 1,000 0,02667314 0,15652578 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,02725884 0,15957366 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,02725884 0,15918635 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,02725884 0,15880091 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,02725884 0,15841733 ! neuron fate determination GO:0048664 7 5 0,000 0,02725884 0,1580356 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02725884 0,15765571 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,02725884 0,15727764 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,02725884 0,15690138 ! polyol transport GO:0015791 12 5 0,000 0,02725884 0,15652691 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,02725884 0,15615423 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,02725884 0,15578331 ! response to superoxide GO:0000303 10 5 0,000 0,02725884 0,15541416 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,02725884 0,15504675 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,02725884 0,15468107 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,02725884 0,15431712 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,02725884 0,15395487 ! female meiosis GO:0007143 7 5 0,000 0,02725884 0,15359432 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,02725884 0,15323546 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,02725884 0,15287826 ! cobalt ion transport GO:0006824 11 5 0,000 0,02725884 0,15252273 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,02725884 0,15216885 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,02725884 0,15181661 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,02725884 0,15146599 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,02725884 0,15111699 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,02725884 0,1507696 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,02725884 0,1504238 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,02725884 0,15007958 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,02725884 0,14973693 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,02725884 0,14939584 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,02725884 0,14905631 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02725884 0,14871831 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,02725884 0,14838184 ! negative chemotaxis GO:0050919 14 5 0,000 0,02725884 0,1480469 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,02725884 0,14771346 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,02725884 0,14738152 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,02725884 0,14705107 ! behavioral response to pain GO:0048266 9 5 0,000 0,02725884 0,14672209 ! clathrin coat assembly GO:0048268 14 5 0,000 0,02725884 0,14639459 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02725884 0,14606854 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,02725884 0,14574394 ! micturition GO:0060073 9 5 0,000 0,02725884 0,14542079 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,02725884 0,14509906 ! copulation GO:0007620 9 5 0,000 0,02725884 0,14477875 ! glial cell fate commitment GO:0021781 13 5 0,000 0,02725884 0,14445986 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,02725884 0,14414236 ! spermidine metabolic process GO:0008216 7 5 0,000 0,02725884 0,14382626 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,02725884 0,14351154 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,02725884 0,1431982 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,02725884 0,14288622 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,02725884 0,1425756 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,02725884 0,14226632 ! grooming behavior GO:0007625 6 5 0,000 0,02725884 0,14195839 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,02725884 0,14165178 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,02725884 0,1413465 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02725884 0,14104253 ! response to protozoan GO:0001562 10 5 0,000 0,02725884 0,14073986 ! positive regulation of glycolysis GO:0045821 14 5 0,000 0,02725884 0,14043849 ! lymph vessel development GO:0001945 10 5 0,000 0,02725884 0,14013841 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,02725884 0,13983961 ! endochondral ossification GO:0001958 16 5 0,000 0,02725884 0,13954207 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,02725884 0,13924581 ! parathyroid gland development GO:0060017 13 5 0,000 0,02725884 0,13895079 ! anagen GO:0042640 6 5 0,000 0,02725884 0,13865703 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,02725884 0,1383645 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,02725884 0,13807321 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,02725884 0,13778314 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,02725884 0,13749429 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,02725884 0,13720664 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,02725884 0,1369202 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,02725884 0,13663495 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,02725884 0,13635088 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,02725884 0,136068 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,02725884 0,13578628 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,02725884 0,13550573 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,02725884 0,13522634 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,02725884 0,1349481 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,02725884 0,134671 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,02725884 0,13439503 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,02725884 0,13412019 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,02725884 0,13384648 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,02725884 0,13357388 ! histidine catabolic process GO:0006548 6 5 0,000 0,02725884 0,13330239 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,02725884 0,133032 ! microvillus organization GO:0032528 7 5 0,000 0,02725884 0,1327627 GO:0030033|microvillus assembly, ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,02725884 0,1324945 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,02725884 0,13222737 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,02725884 0,13196132 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,02725884 0,13169634 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,02725884 0,13143242 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,02725884 0,13116955 ! polyol biosynthetic process GO:0046173 5 5 0,000 0,02725884 0,13090773 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,02725884 0,13064696 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,02725884 0,13038723 ! muscle cell migration GO:0014812 8 5 0,000 0,02725884 0,13012852 ! mitochondrial fission GO:0000266 8 5 0,000 0,02725884 0,12987084 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,02725884 0,12961418 ! mRNA transcription GO:0009299 9 5 0,000 0,02725884 0,12935853 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,02725884 0,12910389 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,02725884 0,12885025 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,02725884 0,1285976 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,02725884 0,12834594 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,02725884 0,12809526 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,02725884 0,12784557 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,02725884 0,12759684 ! response to food GO:0032094 6 5 0,000 0,02725884 0,12734908 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,02725884 0,12710228 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,02725884 0,12685643 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,02725884 0,12661154 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02725884 0,12636758 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,02725884 0,12612457 ! regulation of phospholipase A2 activity GO:0032429 13 5 0,000 0,02725884 0,12588249 ! forebrain neuron development GO:0021884 13 5 0,000 0,02725884 0,12564133 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,02725884 0,1254011 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,02725884 0,12516178 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,02725884 0,12492338 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02725884 0,12468588 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,02725884 0,12444929 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,02725884 0,12421359 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02725884 0,12397878 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,02725884 0,12374486 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,02725884 0,12351182 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,02725884 0,12327965 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,02725884 0,12304836 ! basic amino acid transport GO:0015802 11 5 0,000 0,02725884 0,12281793 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,02725884 0,12258836 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,02725884 0,12235966 ! depyrimidination GO:0045008 10 5 0,000 0,02725884 0,1221318 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,02725884 0,12190479 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02725884 0,12167862 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,02725884 0,12145329 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,02725884 0,12122879 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 0,02725884 0,12100512 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,02725884 0,12078227 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02725884 0,12056025 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,02725884 0,12033904 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,02725884 0,12011864 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,02725884 0,11989904 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,02725884 0,11968025 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,02725884 0,11946225 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02725884 0,11924505 ! response to arsenic GO:0046685 10 5 0,000 0,02725884 0,11902863 ! mast cell degranulation GO:0043303 7 5 0,000 0,02725884 0,118813 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,02725884 0,11859815 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,02725884 0,11838407 ! response to cadmium ion GO:0046686 7 5 0,000 0,02725884 0,11817077 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,02725884 0,11795823 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,02725884 0,11774645 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,02725884 0,11753544 ! decidualization GO:0046697 11 5 0,000 0,02725884 0,11732518 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,02725884 0,11711567 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,02725884 0,11690691 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,02725884 0,11669889 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,02725884 0,11649161 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,02725884 0,11628506 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,02725884 0,11607925 ! neural tube patterning GO:0021532 7 5 0,000 0,02725884 0,11587416 ! embryonic cleavage GO:0040016 6 5 0,000 0,02725884 0,1156698 ! peroxisome fission GO:0016559 5 5 0,000 0,02725884 0,11546615 ! histone demethylation GO:0016577 10 5 0,000 0,02725884 0,11526323 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,02725884 0,11506101 ! mitotic recombination GO:0006312 9 5 0,000 0,02725884 0,1148595 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,02725884 0,1146587 ! metaphase plate congression GO:0051310 7 5 0,000 0,02725884 0,1144586 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02725884 0,11425919 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,02725884 0,11406048 ! enteric nervous system development GO:0048484 8 5 0,000 0,02725884 0,11386246 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,02725884 0,11366512 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,02725884 0,11346847 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,02725884 0,1132725 ! muscle cell proliferation GO:0033002 11 5 0,000 0,02725884 0,1130772 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,02725884 0,11288257 ! plasminogen activation GO:0031639 5 5 0,000 0,02725884 0,11268862 ! B cell homeostasis GO:0001782 13 5 0,000 0,02725884 0,11249533 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,02725884 0,1123027 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,02725884 0,11211073 ! metaphase GO:0051323 8 5 0,000 0,02725884 0,11191941 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,02725884 0,11172875 ! cellular response to nutrient GO:0031670 8 5 0,000 0,02725884 0,11153873 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,02725884 0,11134936 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,02725884 0,11116064 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,02725884 0,11097255 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,02725884 0,11078509 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,02725884 0,11059827 ! response to redox state GO:0051775 5 5 0,000 0,02725884 0,11041208 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,02725884 0,11022651 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,02725884 0,11004157 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,02725884 0,10985724 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,02725884 0,10967354 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02725884 0,10949044 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,02725884 0,10930796 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02725884 0,10912608 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,02725884 0,10894481 ! striatum development GO:0021756 9 5 0,000 0,02725884 0,10876414 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,02725884 0,10858406 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,02725884 0,10840459 ! glial cell migration GO:0008347 11 5 0,000 0,02725884 0,1082257 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,02725884 0,10804741 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,02725884 0,1078697 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,02725884 0,10769257 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,02725884 0,10751602 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,02725884 0,10734006 ! neuroprotection GO:0043526 6 5 0,000 0,02725884 0,10716467 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,02725884 0,10698985 ! regulation of sensory perception GO:0051931 7 5 0,000 0,02725884 0,10681559 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,02725884 0,10664191 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,02725884 0,10646879 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,02725884 0,10629623 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,02725884 0,10612423 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,02725884 0,10595279 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,02725884 0,1057819 ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,02725884 0,10561155 ! spindle assembly GO:0051225 6 5 0,000 0,02725884 0,10544176 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,02725884 0,10527251 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,02725884 0,10510381 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,02725884 0,10493564 ! drug metabolic process GO:0017144 6 5 0,000 0,02725884 0,10476801 ! stem cell division GO:0017145 11 5 0,000 0,02725884 0,10460092 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,02725884 0,10443436 ! organ regeneration GO:0031100 7 5 0,000 0,02725884 0,10426832 ! carnitine metabolic process GO:0009437 7 5 0,000 0,02725884 0,10410282 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,02725884 0,10393784 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,02725884 0,10377338 ! response to calcium ion GO:0051592 81 47 1,000 0,02775942 0,10551211 ! regulation of adaptive immune response GO:0002819 84 47 1,000 0,02775942 0,10534569 ! methylation GO:0032259 90 47 1,000 0,02775942 0,10517979 ! positive regulation of cell cycle GO:0045787 89 48 1,000 0,02886327 0,10919028 ! mitochondrial transport GO:0006839 82 48 1,000 0,02886327 0,10901887 ! cellular component disassembly GO:0022411 86 48 1,000 0,02886327 0,10884799 ! morphogenesis of embryonic epithelium GO:0016331 91 48 1,000 0,02886327 0,10867765 ! regulation of action potential GO:0001508 95 49 1,000 0,02998445 0,11272279 ! regulation of protein complex disassembly GO:0043244 113 49 1,000 0,02998445 0,11254694 ! response to temperature stimulus GO:0009266 76 49 1,000 0,02998445 0,11237163 ! DNA-dependent DNA replication GO:0006261 74 49 1,000 0,02998445 0,11219687 ! regulation of gene expression, epigenetic GO:0040029 105 50 1,000 0,03112275 0,11627536 ! viral infectious cycle GO:0019058 99 51 1,000 0,03227794 0,12040423 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 1,000 0,03227794 0,12021784 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 1,000 0,03227794 0,12003203 ! vesicle organization GO:0016050 107 51 1,000 0,03227794 0,1198468 ! regulation of cell shape GO:0008360 125 51 1,000 0,03227794 0,11966214 ! epithelial tube morphogenesis GO:0060562 98 51 1,000 0,03227794 0,11947804 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,03262132 0,1205636 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,03262132 0,12037869 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,03262132 0,12019434 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,03262132 0,12001056 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,03262132 0,11982734 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,03262132 0,11964467 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,03262132 0,11946256 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,03262132 0,11928101 ! sleep GO:0030431 13 6 0,000 0,03262132 0,11910001 ! response to oxygen radical GO:0000305 11 6 0,000 0,03262132 0,11891955 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,03262132 0,11873964 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,03262132 0,11856028 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,03262132 0,11838146 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,03262132 0,11820317 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,03262132 0,11802542 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,03262132 0,11784821 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,03262132 0,11767152 ! forebrain regionalization GO:0021871 8 6 0,000 0,03262132 0,11749537 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,03262132 0,11731974 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,03262132 0,11714463 ! response to zinc ion GO:0010043 9 6 0,000 0,03262132 0,11697005 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,03262132 0,11679599 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,03262132 0,11662244 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,03262132 0,11644941 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,03262132 0,1162769 ! malate metabolic process GO:0006108 11 6 0,000 0,03262132 0,11610489 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,03262132 0,11593339 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,03262132 0,1157624 ! protein refolding GO:0042026 15 6 0,000 0,03262132 0,11559191 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,03262132 0,11542192 ! opsonization GO:0008228 8 6 0,000 0,03262132 0,11525243 ! mating behavior GO:0007617 7 6 0,000 0,03262132 0,11508344 ! neuron remodeling GO:0016322 15 6 0,000 0,03262132 0,11491494 ! erythrocyte maturation GO:0043249 7 6 0,000 0,03262132 0,11474694 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,03262132 0,11457942 ! equilibrioception GO:0050957 14 6 0,000 0,03262132 0,1144124 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,03262132 0,11424586 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,03262132 0,1140798 ! photoreceptor cell development GO:0042461 10 6 0,000 0,03262132 0,11391423 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,03262132 0,11374914 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,03262132 0,11358452 ! response to interferon-gamma GO:0034341 15 6 0,000 0,03262132 0,11342038 ! toxin metabolic process GO:0009404 11 6 0,000 0,03262132 0,11325672 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,03262132 0,11309352 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,03262132 0,1129308 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,03262132 0,11276854 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,03262132 0,11260675 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,03262132 0,11244542 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,03262132 0,11228456 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,03262132 0,11212415 ! protein lipoylation GO:0009249 10 6 0,000 0,03262132 0,1119642 ! cysteine metabolic process GO:0006534 10 6 0,000 0,03262132 0,11180471 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,03262132 0,11164567 ! glutamate catabolic process GO:0006538 10 6 0,000 0,03262132 0,11148708 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,03262132 0,11132894 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,03262132 0,11117125 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,03262132 0,11101401 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,03262132 0,11085721 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,03262132 0,11070085 ! hyperosmotic response GO:0006972 9 6 0,000 0,03262132 0,11054494 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,03262132 0,11038946 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,03262132 0,11023442 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,03262132 0,11007981 ! urea metabolic process GO:0019627 7 6 0,000 0,03262132 0,10992564 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,03262132 0,10977189 ! neutrophil activation GO:0042119 8 6 0,000 0,03262132 0,10961858 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,03262132 0,1094657 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,03262132 0,10931324 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,03262132 0,1091612 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,03262132 0,10900959 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,03262132 0,1088584 ! neuron apoptosis GO:0051402 9 6 0,000 0,03262132 0,10870762 ! nucleoside salvage GO:0043174 9 6 0,000 0,03262132 0,10855727 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,03262132 0,10840733 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,03262132 0,1082578 ! T cell mediated immunity GO:0002456 16 6 0,000 0,03262132 0,10810868 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,03262132 0,10795998 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 0,03262132 0,10781168 ! carnitine transport GO:0015879 10 6 0,000 0,03262132 0,10766379 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,03262132 0,10751631 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,03262132 0,10736923 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,03262132 0,10722255 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,03262132 0,10707627 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,03262132 0,10693039 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,03262132 0,1067849 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,03262132 0,10663982 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,03262132 0,10649512 ! establishment of spindle localization GO:0051293 12 6 0,000 0,03262132 0,10635082 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,03262132 0,10620691 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,03262132 0,10606338 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,03262132 0,10592025 ! neural nucleus development GO:0048857 14 6 0,000 0,03262132 0,1057775 ! astrocyte development GO:0014002 15 6 0,000 0,03262132 0,10563513 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,03262132 0,10549315 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,03262132 0,10535155 ! interaction with symbiont GO:0051702 13 6 0,000 0,03262132 0,10521033 ! regulation of dendrite development GO:0050773 16 6 0,000 0,03262132 0,10506948 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,03262132 0,10492902 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,03262132 0,10478892 ! response to copper ion GO:0046688 10 6 0,000 0,03262132 0,10464921 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,03262132 0,10450986 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,03262132 0,10437088 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,03262132 0,10423228 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,03262132 0,10409404 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,03262132 0,10395617 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,03262132 0,10381866 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,03262132 0,10368151 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,03262132 0,10354473 ! hair follicle maturation GO:0048820 7 6 0,000 0,03262132 0,10340831 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,03262132 0,10327224 ! Schwann cell development GO:0014044 15 6 0,000 0,03262132 0,10313654 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,03262132 0,10300119 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,03262132 0,10286619 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,03262132 0,10273155 ! subpallium development GO:0021544 10 6 0,000 0,03262132 0,10259726 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,03262132 0,10246332 ! histone ubiquitination GO:0016574 8 6 0,000 0,03262132 0,10232973 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,03262132 0,10219649 ! maintenance of organ identity GO:0048496 9 6 0,000 0,03262132 0,1020636 ! G2 phase GO:0051319 16 6 0,000 0,03262132 0,10193105 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,03262132 0,10179884 ! establishment of planar polarity GO:0001736 7 6 0,000 0,03262132 0,10166698 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,03262132 0,10153545 ! membrane to membrane docking GO:0022614 14 6 0,000 0,03262132 0,10140427 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,03262132 0,10127343 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,03262132 0,10114292 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,03262132 0,10101275 ! receptor internalization GO:0031623 10 6 0,000 0,03262132 0,10088291 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,03262132 0,10075341 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,03262132 0,10062424 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,03262132 0,1004954 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,03262132 0,10036689 ! protein deubiquitination GO:0016579 14 6 0,000 0,03262132 0,1002387 ! protein destabilization GO:0031648 9 6 0,000 0,03262132 0,10011085 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,03262132 0,09998332 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,03262132 0,09985611 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,03262132 0,09972923 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,03262132 0,09960267 ! progesterone metabolic process GO:0042448 10 6 0,000 0,03262132 0,09947643 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,03262132 0,09935051 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,03262132 0,09922491 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,03262132 0,09909963 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,03262132 0,09897466 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,03262132 0,09885001 ! determination of adult lifespan GO:0008340 15 6 0,000 0,03262132 0,09872567 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,03262132 0,09860164 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,03262132 0,09847792 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,03262132 0,09835452 ! catecholamine transport GO:0051937 9 6 0,000 0,03262132 0,09823142 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,03262132 0,09810863 ! sensory cilium assembly GO:0035058 10 6 0,000 0,03262132 0,09798615 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,03262132 0,09786397 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,03262132 0,0977421 ! maternal placenta development GO:0001893 12 6 0,000 0,03262132 0,09762053 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,03262132 0,09749926 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,03262132 0,09737829 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,03262132 0,09725763 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,03262132 0,09713726 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,03262132 0,09701719 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,03262132 0,09689741 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,03262132 0,09677793 ! regulation of angiogenesis GO:0045765 114 52 1,000 0,03344981 0,0991136 ! membrane fusion GO:0006944 110 52 1,000 0,03344981 0,09899169 ! regulation of translational initiation GO:0006446 82 53 1,000 0,03463814 0,10238251 ! cell maturation GO:0048469 100 53 1,000 0,03463814 0,10225689 ! regulation of neuron apoptosis GO:0043523 100 53 1,000 0,03463814 0,10213158 ! heterocycle catabolic process GO:0046700 85 54 1,000 0,03584272 0,10555395 ! regulation of multicellular organism growth GO:0040014 85 55 1,000 0,03706332 0,10901511 ! nuclear export GO:0051168 97 55 1,000 0,03706332 0,108882 ! tRNA transcription GO:0009304 14 7 0,000 0,03795442 0,11136382 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,03795442 0,11122818 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,03795442 0,11109286 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,03795442 0,11095788 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,03795442 0,11082322 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,03795442 0,11068889 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,03795442 0,11055488 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,03795442 0,1104212 ! prostate gland development GO:0030850 13 7 0,000 0,03795442 0,11028784 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,03795442 0,11015481 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,03795442 0,11002209 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,03795442 0,10988969 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,03795442 0,10975761 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,03795442 0,10962585 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,03795442 0,10949441 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,03795442 0,10936327 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,03795442 0,10923246 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,03795442 0,10910195 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,03795442 0,10897176 ! glycolipid transport GO:0046836 10 7 0,000 0,03795442 0,10884188 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,03795442 0,1087123 GO:0051923|sulfation, ! neuron adhesion GO:0007158 12 7 0,000 0,03795442 0,10858304 ! N-terminal protein amino acid acetylation GO:0006474 13 7 0,000 0,03795442 0,10845408 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,03795442 0,10832543 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,03795442 0,10819708 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,03795442 0,10806903 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,03795442 0,10794129 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,03795442 0,10781385 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,03795442 0,10768672 ! mRNA stabilization GO:0048255 18 7 0,000 0,03795442 0,10755988 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,03795442 0,10743333 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,03795442 0,10730709 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,03795442 0,10718114 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,03795442 0,10705549 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,03795442 0,10693013 ! lipoprotein transport GO:0042953 14 7 0,000 0,03795442 0,10680507 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,03795442 0,1066803 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,03795442 0,10655582 ! rhythmic behavior GO:0007622 15 7 0,000 0,03795442 0,10643163 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,03795442 0,10630772 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,03795442 0,10618411 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,03795442 0,10606078 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,03795442 0,10593774 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,03795442 0,10581499 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,03795442 0,10569252 ! mechanosensory behavior GO:0007638 14 7 0,000 0,03795442 0,10557033 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,03795442 0,10544842 ! positive regulation of heart rate GO:0010460 10 7 0,000 0,03795442 0,1053268 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,03795442 0,10520545 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,03795442 0,10508439 ! spinal cord patterning GO:0021511 13 7 0,000 0,03795442 0,1049636 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,03795442 0,10484309 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,03795442 0,10472286 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,03795442 0,1046029 ! adrenal gland development GO:0030325 17 7 0,000 0,03795442 0,10448322 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,03795442 0,10436381 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,03795442 0,10424467 ! ovulation GO:0030728 9 7 0,000 0,03795442 0,10412581 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,03795442 0,10400721 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,03795442 0,10388889 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,03795442 0,10377083 ! microtubule nucleation GO:0007020 20 7 0,000 0,03795442 0,10365305 ! proline biosynthetic process GO:0006561 10 7 0,000 0,03795442 0,10353553 ! thyroid hormone generation GO:0006590 13 7 0,000 0,03795442 0,10341827 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,03795442 0,10330128 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,03795442 0,10318456 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,03795442 0,1030681 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,03795442 0,1029519 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,03795442 0,10283596 ! galactose metabolic process GO:0006012 13 7 0,000 0,03795442 0,10272029 ! response to dietary excess GO:0002021 8 7 0,000 0,03795442 0,10260487 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,03795442 0,10248971 ! intracellular pH reduction GO:0051452 11 7 0,000 0,03795442 0,10237481 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,03795442 0,10226017 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,03795442 0,10214579 ! organ growth GO:0035265 15 7 0,000 0,03795442 0,10203166 ! purine salvage GO:0043101 10 7 0,000 0,03795442 0,10191778 ! nucleoside transport GO:0015858 8 7 0,000 0,03795442 0,10180416 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,03795442 0,1016908 ! parturition GO:0007567 14 7 0,000 0,03795442 0,10157768 ! rRNA modification GO:0000154 14 7 0,000 0,03795442 0,10146482 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,03795442 0,1013522 ! spindle checkpoint GO:0031577 15 7 0,000 0,03795442 0,10123984 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,03795442 0,10112772 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,03795442 0,10101586 ! macrophage differentiation GO:0030225 11 7 0,000 0,03795442 0,10090424 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,03795442 0,10079286 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,03795442 0,10068174 GO:0046676|negative regulation of insulin secretion, ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,03795442 0,10057085 ! fibrinolysis GO:0042730 10 7 0,000 0,03795442 0,10046021 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,03795442 0,10034982 ! eating behavior GO:0042755 7 7 0,000 0,03795442 0,10023966 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,03795442 0,10012975 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,03795442 0,10002008 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,03795442 0,09991065 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,03795442 0,09980146 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,03795442 0,0996925 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,03795442 0,09958379 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,03795442 0,09947531 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,03795442 0,09936707 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,03795442 0,09925906 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,03795442 0,09915129 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,03795442 0,09904375 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,03795442 0,09893644 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,03795442 0,09882937 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,03795442 0,09872252 ! regulation of meiosis GO:0040020 12 7 0,000 0,03795442 0,09861591 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,03795442 0,09850953 ! regulation of lipid transport GO:0032368 14 7 0,000 0,03795442 0,09840338 ! oxygen homeostasis GO:0032364 12 7 0,000 0,03795442 0,09829745 ! transcription termination GO:0006353 13 7 0,000 0,03795442 0,09819176 ! regulation of respiratory burst GO:0060263 11 7 0,000 0,03795442 0,09808629 ! anaphase GO:0051322 17 7 0,000 0,03795442 0,09798105 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,03795442 0,09787603 ! axonal fasciculation GO:0007413 18 7 0,000 0,03795442 0,09777124 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,03795442 0,09766667 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,03795442 0,09756232 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,03795442 0,0974582 ! diuresis GO:0030146 12 7 0,000 0,03795442 0,0973543 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,03795442 0,09725062 ! thiamin metabolic process GO:0006772 7 7 0,000 0,03795442 0,09714716 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,03795442 0,09704393 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,03795442 0,09694091 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,03795442 0,09683811 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,03795442 0,09673552 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,03795442 0,09663316 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,03795442 0,09653101 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,03795442 0,09642908 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,03795442 0,09632736 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,03795442 0,09622585 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,03795442 0,09612456 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,03795442 0,09602349 ! lymph node development GO:0048535 10 7 0,000 0,03795442 0,09592262 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,03795442 0,09582197 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,03795442 0,09572152 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,03795442 0,09562129 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,03795442 0,09552127 ! adult feeding behavior GO:0008343 9 7 0,000 0,03795442 0,09542146 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,03795442 0,09532185 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,03795442 0,09522245 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,03795442 0,09512326 ! muscle adaptation GO:0043500 14 7 0,000 0,03795442 0,09502428 ! embryonic heart tube development GO:0035050 10 7 0,000 0,03795442 0,0949255 ! retina homeostasis GO:0001895 12 7 0,000 0,03795442 0,09482693 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,03795442 0,09472856 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,03795442 0,0946304 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,03795442 0,09453244 ! protein prenylation GO:0018342 18 7 0,000 0,03795442 0,09443468 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,03795442 0,09433712 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,03795442 0,09423977 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,03795442 0,09414261 ! skeletal muscle fiber development GO:0048741 111 56 1,000 0,03829975 0,09490135 ! proton transport GO:0015992 94 56 1,000 0,03829975 0,09480371 ! positive regulation of organelle organization GO:0010638 100 56 1,000 0,03829975 0,09470628 ! muscle fiber development GO:0048747 112 57 1,000 0,0395518 0,09770187 ! positive regulation of cell migration GO:0030335 126 57 1,000 0,0395518 0,09760166 ! regulation of intracellular transport GO:0032386 101 57 1,000 0,0395518 0,09750166 ! maintenance of location GO:0051235 118 57 1,000 0,0395518 0,09740186 ! hydrogen transport GO:0006818 97 58 1,000 0,04081924 0,10042035 ! skeletal system morphogenesis GO:0048705 105 59 1,000 0,04210189 0,10347002 ! DNA catabolic process GO:0006308 86 59 1,000 0,04210189 0,10336444 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,04325829 0,10609526 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,04325829 0,10598722 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 0,000 0,04325829 0,1058794 ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,04325829 0,1057718 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,04325829 0,10566442 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,04325829 0,10555725 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,04325829 0,1054503 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,04325829 0,10534357 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,04325829 0,10523706 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,04325829 0,10513076 ! meiotic prophase I GO:0007128 13 8 0,000 0,04325829 0,10502467 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,04325829 0,1049188 ! oligopeptide transport GO:0006857 15 8 0,000 0,04325829 0,10481314 ! UTP metabolic process GO:0046051 8 8 0,000 0,04325829 0,10470769 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,04325829 0,10460246 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,04325829 0,10449744 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,04325829 0,10439263 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,04325829 0,10428802 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,04325829 0,10418363 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,04325829 0,10407945 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,04325829 0,10397547 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,04325829 0,10387171 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,04325829 0,10376814 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,04325829 0,10366479 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,04325829 0,10356164 ! reflex GO:0060004 16 8 0,000 0,04325829 0,1034587 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,04325829 0,10335596 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,04325829 0,10325342 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,04325829 0,10315109 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,04325829 0,10304896 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,04325829 0,10294703 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,04325829 0,10284531 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,04325829 0,10274378 ! pigment granule organization GO:0048753 16 8 0,000 0,04325829 0,10264245 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,04325829 0,10254133 ! astrocyte differentiation GO:0048708 18 8 0,000 0,04325829 0,1024404 ! histidine metabolic process GO:0006547 16 8 0,000 0,04325829 0,10233967 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,04325829 0,10223914 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,04325829 0,10213881 ! glycine catabolic process GO:0006546 13 8 0,000 0,04325829 0,10203868 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,04325829 0,10193874 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,04325829 0,10183899 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,04325829 0,10173944 ! melanin metabolic process GO:0006582 15 8 0,000 0,04325829 0,10164009 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,04325829 0,10154093 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,04325829 0,10144196 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,04325829 0,10134318 ! macrophage activation GO:0042116 12 8 0,000 0,04325829 0,1012446 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,04325829 0,10114621 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,04325829 0,10104801 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,04325829 0,10095 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,04325829 0,10085218 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,04325829 0,10075455 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,04325829 0,10065711 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,04325829 0,10055985 ! osteoblast development GO:0002076 16 8 0,000 0,04325829 0,10046279 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,04325829 0,10036591 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,04325829 0,10026922 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,04325829 0,10017271 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,04325829 0,10007639 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,04325829 0,09998026 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,04325829 0,09988431 ! response to UV-B GO:0010224 16 8 0,000 0,04325829 0,09978854 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,04325829 0,09969296 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,04325829 0,09959756 ! intermediate filament organization GO:0045109 12 8 0,000 0,04325829 0,09950234 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,04325829 0,09940731 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,04325829 0,09931245 ! cellular extravasation GO:0045123 12 8 0,000 0,04325829 0,09921778 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,04325829 0,09912328 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,04325829 0,09902897 ! response to antibiotic GO:0046677 11 8 0,000 0,04325829 0,09893484 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,04325829 0,09884088 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,04325829 0,09874711 ! DNA topological change GO:0006265 12 8 0,000 0,04325829 0,09865351 ! response to tropane GO:0014073 15 8 0,000 0,04325829 0,09856008 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,04325829 0,09846684 ! melanosome transport GO:0032402 13 8 0,000 0,04325829 0,09837377 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,04325829 0,09828088 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,04325829 0,09818816 ! mast cell activation GO:0045576 14 8 0,000 0,04325829 0,09809562 ! multicellular organismal aging GO:0010259 18 8 0,000 0,04325829 0,09800325 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,04325829 0,09791105 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,04325829 0,09781903 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,04325829 0,09772718 ! nucleosome disassembly GO:0006337 14 8 0,000 0,04325829 0,09763551 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,04325829 0,097544 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,04325829 0,09745267 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,04325829 0,0973615 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,04325829 0,09727051 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,04325829 0,09717969 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,04325829 0,09708904 ! intracellular lipid transport GO:0032365 13 8 0,000 0,04325829 0,09699855 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,04325829 0,09690824 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,04325829 0,09681809 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,04325829 0,09672811 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,04325829 0,0966383 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,04325829 0,09654865 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,04325829 0,09645917 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,04325829 0,09636986 ! hormone catabolic process GO:0042447 17 8 0,000 0,04325829 0,09628071 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,04325829 0,09619173 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,04325829 0,09610291 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,04325829 0,09601425 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,04325829 0,09592576 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,04325829 0,09583743 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,04325829 0,09574926 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,04325829 0,09566126 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,04325829 0,09557341 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,04325829 0,09548573 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,04325829 0,09539821 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,04325829 0,09531085 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,04325829 0,09522365 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,04325829 0,09513661 GO:0006043|glucosamine catabolic process, ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,04325829 0,09504972 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,04325829 0,094963 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,04325829 0,09487643 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,04325829 0,09479003 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,04325829 0,09470378 ! nucleoside metabolic process GO:0009116 81 60 1,000 0,04339953 0,09492661 ! protein amino acid autophosphorylation GO:0046777 141 60 1,000 0,04339953 0,09484039 ! negative regulation of response to stimulus GO:0048585 100 60 1,000 0,04339953 0,09475433 ! response to peptide hormone stimulus GO:0043434 122 61 1,000 0,04471197 0,09753127 ! ear development GO:0043583 103 62 1,000 0,046039 0,10033499 ! viral reproductive process GO:0022415 126 62 1,000 0,046039 0,10024419 ! gonad development GO:0008406 98 62 1,000 0,046039 0,10015355 ! regulation of lipid metabolic process GO:0019216 115 63 1,000 0,04738042 0,10297859 ! regulation of developmental growth GO:0048638 15 9 0,000 0,0485331 0,10538866 ! axon extension GO:0048675 15 9 0,000 0,0485331 0,10529363 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,0485331 0,10519877 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,0485331 0,10510408 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,0485331 0,10500956 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,0485331 0,10491521 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,0485331 0,10482103 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,0485331 0,10472702 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,0485331 0,10463318 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,0485331 0,10453951 ! phosphate transport GO:0006817 19 9 0,000 0,0485331 0,104446 ! reproductive behavior GO:0019098 19 9 0,000 0,0485331 0,10435266 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,0485331 0,10425949 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,0485331 0,10416649 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,0485331 0,10407365 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,0485331 0,10398097 ! GTP metabolic process GO:0046039 9 9 0,000 0,0485331 0,10388846 ! RNA methylation GO:0001510 15 9 0,000 0,0485331 0,10379612 ! elastic fiber assembly GO:0048251 15 9 0,000 0,0485331 0,10370394 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,0485331 0,10361192 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,0485331 0,10352006 ! artery development GO:0060840 24 9 0,000 0,0485331 0,10342837 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,0485331 0,10333684 ! regulation of glycolysis GO:0006110 21 9 0,000 0,0485331 0,10324547 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,0485331 0,10315427 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,0485331 0,10306322 ! chemosensory behavior GO:0007635 20 9 0,000 0,0485331 0,10297234 ! microtubule bundle formation GO:0001578 21 9 0,000 0,0485331 0,10288161 ! leukocyte degranulation GO:0043299 16 9 0,000 0,0485331 0,10279105 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,0485331 0,10270064 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,0485331 0,1026104 ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,0485331 0,10252031 ! protein targeting to ER GO:0045047 22 9 0,000 0,0485331 0,10243038 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,0485331 0,10234061 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,0485331 0,10225099 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,0485331 0,10216153 ! endosome organization GO:0007032 17 9 0,000 0,0485331 0,10207223 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,0485331 0,10198308 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,0485331 0,10189409 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,0485331 0,10180526 ! mannose metabolic process GO:0006013 13 9 0,000 0,0485331 0,10171658 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,0485331 0,10162805 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,0485331 0,10153968 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,0485331 0,10145146 ! receptor clustering GO:0043113 18 9 0,000 0,0485331 0,1013634 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,0485331 0,10127548 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,0485331 0,10118772 ! ruffle organization GO:0031529 15 9 0,000 0,0485331 0,10110011 ! retinol metabolic process GO:0042572 18 9 0,000 0,0485331 0,10101266 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,0485331 0,10092535 ! behavioral fear response GO:0001662 22 9 0,000 0,0485331 0,1008382 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,0485331 0,10075119 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,0485331 0,10066434 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,0485331 0,10057763 GO:0030204|chondroitin sulfate metabolic process, ! protein heterooligomerization GO:0051291 16 9 0,000 0,0485331 0,10049108 ! oligodendrocyte development GO:0014003 10 9 0,000 0,0485331 0,10040467 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,0485331 0,10031841 ! segment specification GO:0007379 13 9 0,000 0,0485331 0,1002323 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,0485331 0,10014634 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,0485331 0,10006052 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,0485331 0,09997486 ! response to amine stimulus GO:0014075 13 9 0,000 0,0485331 0,09988933 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,0485331 0,09980396 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,0485331 0,09971873 ! erythrocyte development GO:0048821 15 9 0,000 0,0485331 0,09963364 ! gas homeostasis GO:0033483 16 9 0,000 0,0485331 0,09954871 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,0485331 0,09946391 ! renal water homeostasis GO:0003091 14 9 0,000 0,0485331 0,09937926 ! postreplication repair GO:0006301 22 9 0,000 0,0485331 0,09929475 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,0485331 0,09921039 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,0485331 0,09912617 ! icosanoid secretion GO:0032309 15 9 0,000 0,0485331 0,0990421 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,0485331 0,09895816 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,0485331 0,09887437 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,0485331 0,09879072 ! regulation of cell division GO:0051302 15 9 0,000 0,0485331 0,09870721 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,0485331 0,09862384 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,0485331 0,09854062 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,0485331 0,09845753 ! sterol catabolic process GO:0016127 11 9 0,000 0,0485331 0,09837458 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,0485331 0,09829178 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,0485331 0,09820911 ! S phase GO:0051320 9 9 0,000 0,0485331 0,09812658 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,0485331 0,09804419 ! musculoskeletal movement GO:0050881 14 9 0,000 0,0485331 0,09796194 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,0485331 0,09787982 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,0485331 0,09779785 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,0485331 0,09771601 ! purine base metabolic process GO:0006144 21 9 0,000 0,0485331 0,09763431 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,0485331 0,09755274 ! pigment granule transport GO:0051904 17 9 0,000 0,0485331 0,09747131 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,0485331 0,09739002 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,0485331 0,09730886 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,0485331 0,09722784 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,0485331 0,09714695 ! mitochondrion localization GO:0051646 15 9 0,000 0,0485331 0,09706619 ! positive regulation of cell motion GO:0051272 146 64 1,000 0,04873604 0,09739113 ! germ cell development GO:0007281 118 65 1,000 0,05010567 0,10004501 ! developmental maturation GO:0021700 116 66 1,000 0,0514891 0,10272204 ! chromosome segregation GO:0007059 113 67 1,000 0,05288615 0,10542178 ! positive regulation of T cell activation GO:0050870 109 67 1,000 0,05288615 0,10533451 ! activation of immune response GO:0002253 105 67 1,000 0,05288615 0,10524738 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,053779 0,10693575 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 0,000 0,053779 0,10684745 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,053779 0,10675929 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,053779 0,10667128 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,053779 0,10658341 ! synapsis GO:0007129 13 10 0,000 0,053779 0,10649569 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,053779 0,10640811 ! N-glycan processing GO:0006491 20 10 0,000 0,053779 0,10632068 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,053779 0,10623338 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,053779 0,10614624 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,053779 0,10605923 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,053779 0,10597237 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,053779 0,10588565 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 0,053779 0,10579907 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,053779 0,10571263 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,053779 0,10562634 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,053779 0,10554018 ! androgen metabolic process GO:0008209 17 10 0,000 0,053779 0,10545417 ! phospholipid efflux GO:0033700 16 10 0,000 0,053779 0,10536829 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,053779 0,10528256 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,053779 0,10519696 ! lung alveolus development GO:0048286 26 10 0,000 0,053779 0,1051115 ! pathogenesis GO:0009405 13 10 0,000 0,053779 0,10502619 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,053779 0,10494101 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,053779 0,10485597 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,053779 0,10477106 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,053779 0,1046863 ! endoderm development GO:0007492 16 10 0,000 0,053779 0,10460167 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,053779 0,10451717 ! arginine catabolic process GO:0006527 13 10 0,000 0,053779 0,10443282 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,053779 0,1043486 ! proline metabolic process GO:0006560 13 10 0,000 0,053779 0,10426451 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,053779 0,10418057 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,053779 0,10409675 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,053779 0,10401307 ! V(D)J recombination GO:0033151 28 10 0,000 0,053779 0,10392953 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,053779 0,10384612 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,053779 0,10376284 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,053779 0,1036797 ! B cell proliferation GO:0042100 18 10 0,000 0,053779 0,10359669 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,053779 0,10351381 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,053779 0,10343107 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,053779 0,10334845 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,053779 0,10326597 ! epithelial cell development GO:0002064 20 10 0,000 0,053779 0,10318362 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,053779 0,1031014 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,053779 0,10301932 ! macroautophagy GO:0016236 17 10 0,000 0,053779 0,10293736 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,053779 0,10285553 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,053779 0,10277384 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,053779 0,10269227 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,053779 0,10261083 ! copper ion homeostasis GO:0055070 13 10 0,000 0,053779 0,10252953 ! regulation of bone resorption GO:0045124 25 10 0,000 0,053779 0,10244835 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,053779 0,1023673 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,053779 0,10228637 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,053779 0,10220558 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,053779 0,10212491 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,053779 0,10204437 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,053779 0,10196396 ! blastoderm segmentation GO:0007350 18 10 0,000 0,053779 0,10188367 ! response to dsRNA GO:0043331 20 10 0,000 0,053779 0,10180351 ! DNA ligation GO:0006266 19 10 0,000 0,053779 0,10172348 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,053779 0,10164357 ! melanosome localization GO:0032400 16 10 0,000 0,053779 0,10156379 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,053779 0,10148413 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,053779 0,10140459 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,053779 0,10132519 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,053779 0,1012459 ! mRNA cleavage GO:0006379 17 10 0,000 0,053779 0,10116674 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,053779 0,10108771 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,053779 0,10100879 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,053779 0,10093 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,053779 0,10085133 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,053779 0,10077279 ! salivary gland development GO:0007431 27 10 0,000 0,053779 0,10069437 ! prophase GO:0051324 15 10 0,000 0,053779 0,10061607 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,053779 0,10053789 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,053779 0,10045983 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,053779 0,10038189 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,053779 0,10030408 ! midbrain development GO:0030901 13 10 0,000 0,053779 0,10022638 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,053779 0,10014881 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,053779 0,10007136 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,053779 0,09999402 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,053779 0,09991681 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,053779 0,09983971 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,053779 0,09976273 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,053779 0,09968587 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 0,053779 0,09960913 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 0,053779 0,09953251 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,053779 0,09945601 ! blastocyst formation GO:0001825 17 10 0,000 0,053779 0,09937962 ! cerebellar cortex development GO:0021695 15 10 0,000 0,053779 0,09930335 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,053779 0,0992272 ! activation of innate immune response GO:0002218 12 10 0,000 0,053779 0,09915116 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,053779 0,09907524 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,053779 0,09899944 ! response to nicotine GO:0035094 20 10 0,000 0,053779 0,09892375 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,053779 0,09884818 ! localization within membrane GO:0051668 20 10 0,000 0,053779 0,09877272 ! viral reproduction GO:0016032 134 68 1,000 0,05429663 0,09964737 ! protein maturation by peptide bond cleavage GO:0051605 105 68 1,000 0,05429663 0,09957141 ! cell cycle checkpoint GO:0000075 137 69 1,000 0,05572035 0,10210446 ! reproductive structure development GO:0048608 113 71 1,000 0,05860676 0,10731191 ! B cell activation GO:0042113 160 71 1,000 0,05860676 0,10723031 ! regulation of MAPKKK cascade GO:0043408 142 71 1,000 0,05860676 0,10714883 ! regulation of immune effector process GO:0002697 137 71 1,000 0,05860676 0,10706747 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,05899614 0,10769706 ! respiratory burst GO:0045730 17 11 0,000 0,05899614 0,10761541 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,05899614 0,10753388 ! neuron fate specification GO:0048665 17 11 0,000 0,05899614 0,10745248 ! telencephalon cell migration GO:0022029 20 11 0,000 0,05899614 0,1073712 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,05899614 0,10729004 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,05899614 0,107209 ! thyroid gland development GO:0030878 26 11 0,000 0,05899614 0,10712809 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 0,000 0,05899614 0,1070473 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,05899614 0,10696663 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,05899614 0,10688609 ! response to pain GO:0048265 24 11 0,000 0,05899614 0,10680566 ! blood vessel remodeling GO:0001974 29 11 0,000 0,05899614 0,10672535 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,05899614 0,10664517 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,05899614 0,10656511 ! bone resorption GO:0045453 16 11 0,000 0,05899614 0,10648516 ! peptide or protein amino-terminal blocking GO:0018409 21 11 0,000 0,05899614 0,10640534 ! ventral spinal cord development GO:0021517 21 11 0,000 0,05899614 0,10632563 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,05899614 0,10624605 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,05899614 0,10616658 ! melanocyte differentiation GO:0030318 21 11 0,000 0,05899614 0,10608724 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,05899614 0,10600801 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,05899614 0,1059289 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,05899614 0,1058499 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,05899614 0,10577103 GO:0043088|regulation of Cdc42 GTPase activity, ! lipid digestion GO:0044241 18 11 0,000 0,05899614 0,10569227 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,05899614 0,10561363 ! UV protection GO:0009650 19 11 0,000 0,05899614 0,10553511 ! adult heart development GO:0007512 14 11 0,000 0,05899614 0,1054567 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,05899614 0,10537841 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,05899614 0,10530024 ! temperature homeostasis GO:0001659 17 11 0,000 0,05899614 0,10522218 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,05899614 0,10514424 ! negative regulation of ossification GO:0030279 26 11 0,000 0,05899614 0,10506641 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,05899614 0,1049887 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,05899614 0,1049111 ! regulation of organ growth GO:0046620 13 11 0,000 0,05899614 0,10483362 ! pigment granule localization GO:0051875 20 11 0,000 0,05899614 0,10475625 ! vasoconstriction GO:0042310 18 11 0,000 0,05899614 0,104679 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,05899614 0,10460186 ! embryonic axis specification GO:0000578 18 11 0,000 0,05899614 0,10452483 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,05899614 0,10444792 ! snRNA metabolic process GO:0016073 24 11 0,000 0,05899614 0,10437112 GO:0016180|snRNA processing, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,05899614 0,10429443 ! zymogen activation GO:0031638 15 11 0,000 0,05899614 0,10421786 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,05899614 0,1041414 ! neuroblast proliferation GO:0007405 24 11 0,000 0,05899614 0,10406505 ! nucleosome positioning GO:0016584 15 11 0,000 0,05899614 0,10398881 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,05899614 0,10391268 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,05899614 0,10383667 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,05899614 0,10376076 ! acid secretion GO:0046717 18 11 0,000 0,05899614 0,10368497 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,05899614 0,10360929 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,05899614 0,10353371 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,05899614 0,10345825 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,05899614 0,1033829 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,05899614 0,10330766 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,05899614 0,10323252 ! cholesterol efflux GO:0033344 19 11 0,000 0,05899614 0,1031575 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,05899614 0,10308259 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,05899614 0,10300778 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,05899614 0,10293308 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,05899614 0,10285849 ! embryonic gut development GO:0048566 15 11 0,000 0,05899614 0,10278401 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,05899614 0,10270964 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,05899614 0,10263537 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,05899614 0,10256121 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,05899614 0,10248716 ! defense response to fungus GO:0050832 13 11 0,000 0,05899614 0,10241322 ! developmental induction GO:0031128 19 11 0,000 0,05899614 0,10233938 GO:0045168|cell-cell signaling involved in cell fate specification, ! prepulse inhibition GO:0060134 18 11 0,000 0,05899614 0,10226565 ! sequestering of metal ion GO:0051238 14 11 0,000 0,05899614 0,10219202 ! lamellipodium assembly GO:0030032 20 11 0,000 0,05899614 0,1021185 ! nucleus localization GO:0051647 19 11 0,000 0,05899614 0,10204509 ! regulation of synapse organization GO:0050807 17 11 0,000 0,05899614 0,10197178 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 1,000 0,06006908 0,10375176 ! learning or memory GO:0007611 147 73 1,000 0,0615439 0,10622283 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,0641847 0,11070135 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,0641847 0,11062205 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 0,0641847 0,11054287 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,0641847 0,11046379 ! virus-host interaction GO:0019048 29 12 0,000 0,0641847 0,11038484 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,0641847 0,11030599 ! cartilage condensation GO:0001502 20 12 0,000 0,0641847 0,11022726 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,0641847 0,11014863 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,0641847 0,11007012 ! protein complex disassembly GO:0043241 27 12 0,000 0,0641847 0,10999173 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,0641847 0,10991344 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,0641847 0,10983527 ! hippocampus development GO:0021766 26 12 0,000 0,0641847 0,1097572 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 0,0641847 0,10967925 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,0641847 0,10960141 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,0641847 0,10952368 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,0641847 0,10944606 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,0641847 0,10936854 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,0641847 0,10929114 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,0641847 0,10921385 ! drug transport GO:0015893 16 12 0,000 0,0641847 0,10913667 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,0641847 0,10905959 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,0641847 0,10898263 ! polyamine metabolic process GO:0006595 17 12 0,000 0,0641847 0,10890577 ! focal adhesion formation GO:0048041 35 12 0,000 0,0641847 0,10882902 ! mitotic spindle organization GO:0007052 21 12 0,000 0,0641847 0,10875238 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,0641847 0,10867585 ! forebrain cell migration GO:0021885 21 12 0,000 0,0641847 0,10859943 ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,0641847 0,10852311 ! entry into host cell GO:0030260 32 12 0,000 0,0641847 0,1084469 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,0641847 0,1083708 ! monoamine transport GO:0015844 18 12 0,000 0,0641847 0,1082948 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,0641847 0,10821891 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,0641847 0,10814313 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,0641847 0,10806745 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,0641847 0,10799188 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,0641847 0,10791641 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,0641847 0,10784105 ! protein homotetramerization GO:0051289 21 12 0,000 0,0641847 0,1077658 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,0641847 0,10769065 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,0641847 0,1076156 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,0641847 0,10754066 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,0641847 0,10746582 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,0641847 0,10739109 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,0641847 0,10731646 ! cranial nerve development GO:0021545 20 12 0,000 0,0641847 0,10724193 ! fucose catabolic process GO:0019317 22 12 0,000 0,0641847 0,10716751 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,0641847 0,10709319 ! histone acetylation GO:0016573 26 12 0,000 0,0641847 0,10701898 ! histone methylation GO:0016571 26 12 0,000 0,0641847 0,10694487 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,0641847 0,10687085 ! autonomic nervous system development GO:0048483 24 12 0,000 0,0641847 0,10679695 ! gland morphogenesis GO:0022612 29 12 0,000 0,0641847 0,10672314 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,0641847 0,10664944 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,0641847 0,10657584 ! T cell homeostasis GO:0043029 25 12 0,000 0,0641847 0,10650233 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,0641847 0,10642894 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,0641847 0,10635564 ! spleen development GO:0048536 22 12 0,000 0,0641847 0,10628244 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,0641847 0,10620934 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,0641847 0,10613635 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,0641847 0,10606345 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,0641847 0,10599066 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,0641847 0,10591796 ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,0641847 0,10584536 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,0641847 0,10577287 ! response to cold GO:0009409 17 12 0,000 0,0641847 0,10570047 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,0641847 0,10562817 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,0641847 0,10555597 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 1,000 0,06453033 0,10605189 ! phosphoinositide-mediated signaling GO:0048015 131 75 1,000 0,06453033 0,1059795 ! cytosolic calcium ion homeostasis GO:0051480 135 76 1,000 0,06604158 0,10838748 ! development of primary sexual characteristics GO:0045137 124 76 1,000 0,06604158 0,10831359 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 0,06756462 0,11073602 ! blood coagulation GO:0007596 146 78 1,000 0,06909928 0,11317417 GO:0050817|coagulation, ! protein oligomerization GO:0051259 139 78 1,000 0,06909928 0,11309718 ! cGMP metabolic process GO:0046068 18 13 0,000 0,06934482 0,11342191 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,06934482 0,11334486 ! regulation of chemokine production GO:0032642 18 13 0,000 0,06934482 0,11326791 ! peroxisomal transport GO:0043574 24 13 0,000 0,06934482 0,11319106 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,06934482 0,11311432 ! lipid localization GO:0010876 28 13 0,000 0,06934482 0,11303769 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,06934482 0,11296116 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,06934482 0,11288473 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,06934482 0,1128084 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,06934482 0,11273218 ! endocrine pancreas development GO:0031018 22 13 0,000 0,06934482 0,11265606 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,06934482 0,11258005 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,06934482 0,11250413 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,06934482 0,11242832 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,06934482 0,11235261 ! methionine metabolic process GO:0006555 27 13 0,000 0,06934482 0,112277 ! plasma membrane organization GO:0007009 24 13 0,000 0,06934482 0,1122015 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,06934482 0,11212609 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,06934482 0,11205079 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,06934482 0,11197559 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,06934482 0,11190049 ! cytokine metabolic process GO:0042107 22 13 0,000 0,06934482 0,11182549 ! exocrine system development GO:0035272 32 13 0,000 0,06934482 0,11175059 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 0,06934482 0,11167579 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,06934482 0,11160109 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,06934482 0,11152649 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,06934482 0,11145199 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,06934482 0,11137759 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,06934482 0,11130329 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,06934482 0,11122909 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,06934482 0,11115498 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,06934482 0,11108098 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,06934482 0,11100707 ! ribosome assembly GO:0042255 17 13 0,000 0,06934482 0,11093326 ! regulation of monooxygenase activity GO:0032768 33 13 0,000 0,06934482 0,11085955 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,06934482 0,11078594 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,06934482 0,11071243 ! chromatin silencing GO:0006342 26 13 0,000 0,06934482 0,11063901 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,06934482 0,11056569 ! regulation of epidermis development GO:0045682 19 13 0,000 0,06934482 0,11049247 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,06934482 0,11041934 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,06934482 0,11034631 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,06934482 0,11027338 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,06934482 0,11020055 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,06934482 0,11012781 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,06934482 0,11005516 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,06934482 0,10998262 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,06934482 0,10991016 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,06934482 0,10983781 ! embryonic placenta development GO:0001892 23 13 0,000 0,06934482 0,10976554 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,06934482 0,10969338 ! insulin secretion GO:0030073 23 13 0,000 0,06934482 0,10962131 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,06934482 0,10954933 ! acrosome reaction GO:0007340 18 13 0,000 0,06934482 0,10947745 ! positive regulation of phosphorylation GO:0042327 129 79 1,000 0,07064538 0,11145756 ! response to metal ion GO:0010038 140 80 1,000 0,07220275 0,11383998 ! muscle cell differentiation GO:0042692 159 80 1,000 0,07220275 0,11376543 ! protein import into nucleus GO:0006606 158 80 1,000 0,07220275 0,11369098 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 1,000 0,07377122 0,11608474 GO:0045937|positive regulation of phosphate metabolic process, ! nuclear import GO:0051170 161 81 1,000 0,07377122 0,11600887 ! regulation of neuron differentiation GO:0045664 167 81 1,000 0,07377122 0,11593309 ! rRNA transcription GO:0009303 25 14 0,000 0,07447665 0,11696529 ! lactation GO:0007595 26 14 0,000 0,07447665 0,11688899 ! N-terminal protein amino acid modification GO:0031365 27 14 0,000 0,07447665 0,11681279 ! reproductive cellular process GO:0048610 20 14 0,000 0,07447665 0,11673669 ! tRNA modification GO:0006400 20 14 0,000 0,07447665 0,11666069 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,07447665 0,11658479 ! water transport GO:0006833 21 14 0,000 0,07447665 0,11650899 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,07447665 0,11643328 ! non-recombinational repair GO:0000726 25 14 0,000 0,07447665 0,11635768 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,07447665 0,11628217 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,07447665 0,11620676 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,07447665 0,11613145 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,07447665 0,11605623 ! RNA polyadenylation GO:0043631 30 14 0,000 0,07447665 0,11598112 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,07447665 0,1159061 ! palate development GO:0060021 31 14 0,000 0,07447665 0,11583117 ! regulated secretory pathway GO:0045055 23 14 0,000 0,07447665 0,11575635 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,07447665 0,11568162 ! arginine metabolic process GO:0006525 17 14 0,000 0,07447665 0,11560698 ! regulation of heart rate GO:0002027 24 14 0,000 0,07447665 0,11553245 ! organic alcohol transport GO:0015850 29 14 0,000 0,07447665 0,115458 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,07447665 0,11538366 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,07447665 0,11530941 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,07447665 0,11523526 ! neutral amino acid transport GO:0015804 26 14 0,000 0,07447665 0,1151612 ! L-amino acid transport GO:0015807 30 14 0,000 0,07447665 0,11508723 ! stem cell development GO:0048864 43 14 0,000 0,07447665 0,11501337 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,07447665 0,11493959 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,07447665 0,11486591 ! cerebellum development GO:0021549 21 14 0,000 0,07447665 0,11479233 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,07447665 0,11471884 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,07447665 0,11464544 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,07447665 0,11457214 ! cofactor transport GO:0051181 26 14 0,000 0,07447665 0,11449893 ! NADP metabolic process GO:0006739 24 14 0,000 0,07447665 0,11442581 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,07447665 0,11435279 ! intestinal absorption GO:0050892 25 14 0,000 0,07447665 0,11427986 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,07447665 0,11420703 ! oxygen transport GO:0015671 21 14 0,000 0,07447665 0,11413428 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,07447665 0,11406163 ! male genitalia development GO:0030539 24 14 0,000 0,07447665 0,11398907 ! regulation of RNA stability GO:0043487 32 14 0,000 0,07447665 0,11391661 ! regulation of axon extension GO:0030516 37 14 0,000 0,07447665 0,11384423 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,07447665 0,11377195 ! response to nutrient GO:0007584 125 82 1,000 0,07535063 0,11503403 ! hemostasis GO:0007599 158 84 1,000 0,07854159 0,11982947 ! negative regulation of transport GO:0051051 153 84 1,000 0,07854159 0,11975353 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,07958036 0,12126051 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,07958036 0,12118376 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! superoxide anion generation GO:0042554 20 15 0,000 0,07958036 0,12110711 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,07958036 0,12103056 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,07958036 0,1209541 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,07958036 0,12087774 ! copper ion transport GO:0006825 20 15 0,000 0,07958036 0,12080148 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,07958036 0,12072531 ! sulfate transport GO:0008272 23 15 0,000 0,07958036 0,12064924 ! response to cAMP GO:0051591 22 15 0,000 0,07958036 0,12057326 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,07958036 0,12049738 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,07958036 0,1204216 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,07958036 0,12034591 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,07958036 0,12027031 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,07958036 0,12019482 ! response to hexose stimulus GO:0009746 22 15 0,000 0,07958036 0,12011941 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,07958036 0,1200441 ! pituitary gland development GO:0021983 29 15 0,000 0,07958036 0,11996889 ! vesicle coating GO:0006901 33 15 0,000 0,07958036 0,11989376 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,07958036 0,11981874 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,07958036 0,1197438 ! regulation of exocytosis GO:0017157 22 15 0,000 0,07958036 0,11966896 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,07958036 0,11959422 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,07958036 0,11951956 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,07958036 0,119445 ! regulation of vasodilation GO:0042312 26 15 0,000 0,07958036 0,11937054 ! histone deacetylation GO:0016575 20 15 0,000 0,07958036 0,11929616 ! mRNA splice site selection GO:0006376 38 15 0,000 0,07958036 0,11922188 ! tissue regeneration GO:0042246 26 15 0,000 0,07958036 0,11914769 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,07958036 0,1190736 ! water homeostasis GO:0030104 27 15 0,000 0,07958036 0,11899959 ! muscle maintenance GO:0046716 26 15 0,000 0,07958036 0,11892568 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,07958036 0,11885186 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,07958036 0,11877813 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,07958036 0,11870449 ! dopamine metabolic process GO:0042417 35 15 0,000 0,07958036 0,11863094 ! heme biosynthetic process GO:0006783 29 15 0,000 0,07958036 0,11855749 ! cell killing GO:0001906 29 15 0,000 0,07958036 0,11848412 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,07958036 0,11841085 ! detection of bacterium GO:0016045 18 15 0,000 0,07958036 0,11833766 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,07958036 0,11826457 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,07958036 0,11819157 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,07958036 0,11811866 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,07958036 0,11804583 ! peptide hormone processing GO:0016486 23 15 0,000 0,07958036 0,1179731 ! response to unfolded protein GO:0006986 131 85 1,000 0,08015282 0,11874857 ! one-carbon metabolic process GO:0006730 154 85 1,000 0,08015282 0,11867549 ! positive regulation of cell activation GO:0050867 145 85 1,000 0,08015282 0,11860251 GO:0002696|positive regulation of leukocyte activation, ! response to inorganic substance GO:0010035 153 86 1,000 0,08177432 0,12092748 ! oxidative phosphorylation GO:0006119 133 86 1,000 0,08177432 0,1208532 ! tube morphogenesis GO:0035239 176 86 1,000 0,08177432 0,12077901 ! alcohol catabolic process GO:0046164 130 86 1,000 0,08177432 0,12070491 ! protein localization in nucleus GO:0034504 176 87 1,000 0,08340593 0,12303781 ! regulation of protein transport GO:0051223 154 87 1,000 0,08340593 0,12296242 GO:0070201|regulation of establishment of protein localization, ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,08465609 0,12472906 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,08465609 0,12465272 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,08465609 0,12457648 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,08465609 0,12450034 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,08465609 0,12442428 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,08465609 0,12434832 ! bone remodeling GO:0046849 27 16 0,000 0,08465609 0,12427245 ! filopodium assembly GO:0046847 32 16 0,000 0,08465609 0,12419668 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,08465609 0,12412099 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,08465609 0,1240454 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,08465609 0,1239699 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,08465609 0,1238945 ! startle response GO:0001964 28 16 0,000 0,08465609 0,12381918 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,08465609 0,12374396 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,08465609 0,12366882 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,08465609 0,12359378 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,08465609 0,12351883 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,08465609 0,12344397 ! protein polyubiquitination GO:0000209 34 16 0,000 0,08465609 0,1233692 ! glutamate metabolic process GO:0006536 22 16 0,000 0,08465609 0,12329452 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,08465609 0,12321993 ! response to osmotic stress GO:0006970 25 16 0,000 0,08465609 0,12314544 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,08465609 0,12307103 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,08465609 0,12299671 ! fructose metabolic process GO:0006000 25 16 0,000 0,08465609 0,12292248 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,08465609 0,12284834 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,08465609 0,12277429 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,08465609 0,12270033 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,08465609 0,12262646 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,08465609 0,12255268 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 0,08465609 0,12247898 ! DNA replication initiation GO:0006270 27 16 0,000 0,08465609 0,12240538 ! neuron recognition GO:0008038 35 16 0,000 0,08465609 0,12233186 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,08465609 0,12225843 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,08465609 0,12218509 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,08465609 0,12211184 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,08465609 0,12203868 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,08465609 0,1219656 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,08465609 0,12189261 GO:0046466|membrane lipid catabolic process, ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,08465609 0,12181971 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,08465609 0,12174689 ! positive regulation of protein modification process GO:0031401 136 88 1,000 0,08504751 0,12223674 ! ATP biosynthetic process GO:0006754 159 88 1,000 0,08504751 0,12216376 ! regulation of cell morphogenesis GO:0022604 215 89 1,000 0,08669888 0,12446152 ! ossification GO:0001503 188 90 1,000 0,0883599 0,12677038 ! sex differentiation GO:0007548 145 90 1,000 0,0883599 0,12669483 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,089704 0,12854545 ! metencephalon development GO:0022037 30 17 0,000 0,089704 0,12846894 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,089704 0,12839251 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,089704 0,12831618 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,089704 0,12823994 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,089704 0,12816379 ! signal complex assembly GO:0007172 41 17 0,000 0,089704 0,12808773 ! endothelial cell migration GO:0043542 28 17 0,000 0,089704 0,12801175 ! inositol metabolic process GO:0006020 28 17 0,000 0,089704 0,12793587 ! gene silencing by RNA GO:0031047 36 17 0,000 0,089704 0,12786008 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,089704 0,12778438 ! glial cell development GO:0021782 27 17 0,000 0,089704 0,12770877 ! limbic system development GO:0021761 36 17 0,000 0,089704 0,12763325 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,089704 0,12755781 ! adult walking behavior GO:0007628 33 17 0,000 0,089704 0,12748247 ! heart looping GO:0001947 30 17 0,000 0,089704 0,12740721 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,089704 0,12733205 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,089704 0,12725697 ! myoblast differentiation GO:0045445 45 17 0,000 0,089704 0,12718198 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,089704 0,12710708 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,089704 0,12703226 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,089704 0,12695754 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,089704 0,1268829 ! glycine metabolic process GO:0006544 28 17 0,000 0,089704 0,12680835 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 0,000 0,089704 0,12673389 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,089704 0,12665952 ! NAD metabolic process GO:0019674 29 17 0,000 0,089704 0,12658523 ! membrane budding GO:0006900 37 17 0,000 0,089704 0,12651103 ! regulation of protein binding GO:0043393 33 17 0,000 0,089704 0,12643692 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,089704 0,12636289 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,089704 0,12628895 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,089704 0,1262151 ! genitalia development GO:0048806 30 17 0,000 0,089704 0,12614133 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,089704 0,12606765 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,089704 0,12599406 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,089704 0,12592055 ! steroid catabolic process GO:0006706 31 17 0,000 0,089704 0,12584712 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,089704 0,12577379 ! gas transport GO:0015669 25 17 0,000 0,089704 0,12570053 ! organic cation transport GO:0015695 31 17 0,000 0,089704 0,12562737 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,089704 0,12555429 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,089704 0,12548129 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,089704 0,12540838 ! microspike assembly GO:0030035 36 17 0,000 0,089704 0,12533555 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,089704 0,12526281 ! bone development GO:0060348 189 91 1,000 0,09003041 0,12564569 ! response to protein stimulus GO:0051789 149 91 1,000 0,09003041 0,12557285 ! carbohydrate biosynthetic process GO:0016051 141 93 1,000 0,09339928 0,13019622 ! regulation of membrane potential GO:0042391 164 93 1,000 0,09339928 0,13012083 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,09472423 0,13189034 ! neuron maturation GO:0042551 42 18 0,000 0,09472423 0,13181406 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,09472423 0,13173787 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,09472423 0,13166176 ! phosphoinositide phosphorylation GO:0046854 33 18 0,000 0,09472423 0,13158574 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,09472423 0,13150981 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,09472423 0,13143397 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,09472423 0,13135822 ! memory GO:0007613 31 18 0,000 0,09472423 0,13128255 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,09472423 0,13120697 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,09472423 0,13113148 ! patterning of blood vessels GO:0001569 39 18 0,000 0,09472423 0,13105607 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,09472423 0,13098075 GO:0042744|hydrogen peroxide catabolic process, ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,09472423 0,13090552 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,09472423 0,13083037 ! glutamine metabolic process GO:0006541 29 18 0,000 0,09472423 0,13075531 ! response to retinoic acid GO:0032526 26 18 0,000 0,09472423 0,13068034 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,09472423 0,13060545 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,09472423 0,13053065 ! response to fungus GO:0009620 21 18 0,000 0,09472423 0,13045593 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,09472423 0,1303813 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,09472423 0,13030675 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,09472423 0,13023229 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,09472423 0,13015791 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,09472423 0,13008362 ! vitamin transport GO:0051180 27 18 0,000 0,09472423 0,13000942 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,09472423 0,1299353 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,09472423 0,12986126 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,09472423 0,12978731 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,09472423 0,12971344 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,09472423 0,12963965 ! nerve development GO:0021675 28 18 0,000 0,09472423 0,12956595 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,09472423 0,12949233 ! transcription initiation GO:0006352 153 94 1,000 0,09509734 0,12992856 ! forebrain development GO:0030900 188 95 1,000 0,09680428 0,13218564 ! regulation of Rho protein signal transduction GO:0035023 213 95 1,000 0,09680428 0,13211067 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 1,000 0,09851996 0,13437587 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! positive regulation of immune response GO:0050778 156 96 1,000 0,09851996 0,13429973 ! protein secretion GO:0009306 39 19 0,000 0,09971695 0,13585446 ! positive regulation of translation GO:0045727 30 19 0,000 0,09971695 0,13577758 ! negative regulation of defense response GO:0031348 25 19 0,000 0,09971695 0,13570078 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,09971695 0,13562407 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,09971695 0,13554745 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,09971695 0,13547091 ! lipid phosphorylation GO:0046834 35 19 0,000 0,09971695 0,13539446 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,09971695 0,1353181 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,09971695 0,13524182 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,09971695 0,13516562 ! bile acid metabolic process GO:0008206 29 19 0,000 0,09971695 0,13508952 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,09971695 0,1350135 ! cerebral cortex development GO:0021987 36 19 0,000 0,09971695 0,13493756 ! pigmentation during development GO:0048066 41 19 0,000 0,09971695 0,13486171 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,09971695 0,13478595 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,09971695 0,13471027 ! heme metabolic process GO:0042168 36 19 0,000 0,09971695 0,13463467 ! actin filament bundle formation GO:0051017 42 19 0,000 0,09971695 0,13455916 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,09971695 0,13448374 ! plasma membrane fusion GO:0045026 28 19 0,000 0,09971695 0,13440839 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,09971695 0,13433314 ! peptide cross-linking GO:0018149 37 19 0,000 0,09971695 0,13425797 ! protein export from nucleus GO:0006611 36 19 0,000 0,09971695 0,13418288 ! heart process GO:0003015 30 19 0,000 0,09971695 0,13410787 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,09971695 0,13403295 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,09971695 0,13395812 ! visual learning GO:0008542 36 19 0,000 0,09971695 0,13388336 ! G1 phase GO:0051318 40 19 0,000 0,09971695 0,13380869 ! cell-cell junction organization GO:0045216 35 19 0,000 0,09971695 0,1337341 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,09971695 0,1336596 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,09971695 0,13358518 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,09971695 0,13351084 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,09971695 0,13343659 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,09971695 0,13336241 ! cilium assembly GO:0042384 37 19 0,000 0,09971695 0,13328832 ! peptide hormone secretion GO:0030072 31 19 0,000 0,09971695 0,13321432 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 1,000 0,10024423 0,1338444 ! regulation of protein localization GO:0032880 176 97 1,000 0,10024423 0,13377017 ! response to virus GO:0009615 160 98 1,000 0,10197694 0,13600694 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 1,000 0,10197694 0,13593159 ! Golgi vesicle transport GO:0048193 207 99 1,000 0,10371795 0,13817574 ! skeletal muscle tissue development GO:0007519 186 99 1,000 0,10371795 0,13809927 GO:0060538|skeletal muscle organ development, ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,1046823 0,1393062 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,1046823 0,13922919 ! positive regulation of ossification GO:0045778 47 20 0,000 0,1046823 0,13915227 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,1046823 0,13907543 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,1046823 0,13899868 ! protein amino acid acetylation GO:0006473 39 20 0,000 0,1046823 0,13892201 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 0,000 0,1046823 0,13884543 ! cAMP metabolic process GO:0046058 36 20 0,000 0,1046823 0,13876893 ! response to vitamin GO:0033273 31 20 0,000 0,1046823 0,13869251 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,1046823 0,13861618 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 0,1046823 0,13853994 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,1046823 0,13846378 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,1046823 0,1383877 ! retinoid metabolic process GO:0001523 32 20 0,000 0,1046823 0,1383117 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,1046823 0,13823579 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,1046823 0,13815996 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,1046823 0,13808421 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,1046823 0,13800855 GO:0032392|DNA geometric change, ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 0,000 0,1046823 0,13793297 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,1046823 0,13785748 ! body fluid secretion GO:0007589 31 20 0,000 0,1046823 0,13778206 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,1046823 0,13770673 ! peptide secretion GO:0002790 35 20 0,000 0,1046823 0,13763148 ! stem cell differentiation GO:0048863 53 20 0,000 0,1046823 0,13755631 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,1046823 0,13748123 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,1046823 0,13740622 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,1046823 0,1373313 ! sensory perception of pain GO:0019233 30 20 0,000 0,1046823 0,13725646 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,1046823 0,1371817 ! diencephalon development GO:0021536 34 20 0,000 0,1046823 0,13710703 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,1046823 0,13703243 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,1046823 0,13695792 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,1046823 0,13688348 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,1046823 0,13680913 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,1046823 0,13673486 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,1046823 0,13666067 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,1046823 0,13658655 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,1046823 0,13651252 ! regulation of glucose import GO:0046324 29 20 0,000 0,1046823 0,13643857 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,1046823 0,1363647 ! actin filament-based movement GO:0030048 43 20 0,000 0,1046823 0,13629091 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,1046823 0,1362172 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,1046823 0,13614357 ! negative regulation of translation GO:0017148 29 20 0,000 0,1046823 0,13607002 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,1046823 0,13599655 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,10962042 0,14233499 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,10962042 0,14225822 ! hormone secretion GO:0046879 38 21 0,000 0,10962042 0,14218153 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,10962042 0,14210492 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,10962042 0,1420284 ! axis specification GO:0009798 38 21 0,000 0,10962042 0,14195196 ! ovarian follicle development GO:0001541 35 21 0,000 0,10962042 0,1418756 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,10962042 0,14179932 ! smooth muscle contraction GO:0006939 46 21 0,000 0,10962042 0,14172312 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,10962042 0,14164701 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,10962042 0,14157098 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,10962042 0,14149503 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,10962042 0,14141916 ! cytolysis GO:0019835 24 21 0,000 0,10962042 0,14134337 ! vasodilation GO:0042311 39 21 0,000 0,10962042 0,14126767 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,10962042 0,14119204 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,10962042 0,1411165 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,10962042 0,14104103 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,10962042 0,14096565 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,10962042 0,14089035 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,10962042 0,14081513 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,10962042 0,14073999 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,10962042 0,14066493 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,10962042 0,14058994 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,10962042 0,14051504 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,10962042 0,14044022 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,10962042 0,14036548 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,10962042 0,14029082 ! collagen catabolic process GO:0030574 28 21 0,000 0,10962042 0,14021623 ! sperm-egg recognition GO:0035036 21 21 0,000 0,10962042 0,14014173 ! gut development GO:0048565 39 21 0,000 0,10962042 0,1400673 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,11453147 0,14626472 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,11453147 0,14618712 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,11453147 0,14610961 GO:0034105|positive regulation of tissue remodeling, ! regulation of chemotaxis GO:0050920 40 22 0,000 0,11453147 0,14603218 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,11453147 0,14595483 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,11453147 0,14587757 ! regeneration GO:0031099 41 22 0,000 0,11453147 0,14580038 ! keratinization GO:0031424 28 22 0,000 0,11453147 0,14572328 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,11453147 0,14564626 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,11453147 0,14556932 ! sensory perception of taste GO:0050909 28 22 0,000 0,11453147 0,14549246 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,11453147 0,14541569 ! vacuolar transport GO:0007034 36 22 0,000 0,11453147 0,14533899 ! lysosome organization GO:0007040 41 22 0,000 0,11453147 0,14526237 ! central nervous system neuron development GO:0021954 46 22 0,000 0,11453147 0,14518584 ! fucose metabolic process GO:0006004 39 22 0,000 0,11453147 0,14510939 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,11453147 0,14503301 ! ureteric bud development GO:0001657 43 22 0,000 0,11453147 0,14495672 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,11453147 0,14488051 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,11453147 0,14480437 ! positive regulation of intracellular transport GO:0032388 37 22 0,000 0,11453147 0,14472832 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,11453147 0,14465235 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,11453147 0,14457646 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,11453147 0,14450064 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,11453147 0,14442491 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,11453147 0,14434925 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,11453147 0,14427368 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,11453147 0,14419818 ! protein stabilization GO:0050821 39 22 0,000 0,11453147 0,14412276 ! positive regulation of DNA replication GO:0045740 43 23 0,000 0,1194156 0,15019024 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,1194156 0,15011177 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,1194156 0,15003339 ! viral genome replication GO:0019079 41 23 0,000 0,1194156 0,14995508 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,1194156 0,14987686 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,1194156 0,14979871 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,1194156 0,14972065 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,1194156 0,14964267 GO:0006044|N-acetylglucosamine metabolic process, ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,1194156 0,14956477 ! visual behavior GO:0007632 42 23 0,000 0,1194156 0,14948696 ! regulation of cell-matrix adhesion GO:0001952 78 23 0,000 0,1194156 0,14940922 GO:0010810|regulation of cell-substrate adhesion, ! response to ethanol GO:0045471 46 23 0,000 0,1194156 0,14933157 ! peroxisome organization GO:0007031 37 23 0,000 0,1194156 0,14925399 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,1194156 0,1491765 ! vesicle targeting GO:0006903 43 23 0,000 0,1194156 0,14909908 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,1194156 0,14902175 GO:0051693|actin filament capping, ! sex determination GO:0007530 47 23 0,000 0,1194156 0,1489445 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,1194156 0,14886732 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,1194156 0,14879023 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,1194156 0,14871322 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,1194156 0,14863628 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,1194156 0,14855943 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,1194156 0,14848265 ! fatty acid transport GO:0015908 44 23 0,000 0,1194156 0,14840596 ! platelet activation GO:0030168 37 23 0,000 0,1194156 0,14832934 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,1194156 0,1482528 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,1194156 0,14817634 ! hormone transport GO:0009914 40 23 0,000 0,1194156 0,14809997 ! cell-cell recognition GO:0009988 25 23 0,000 0,1194156 0,14802366 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,1194156 0,14794744 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,1194156 0,1478713 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,1194156 0,14779523 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,1194156 0,14771925 ! positive regulation of fibroblast proliferation GO:0048146 43 24 0,000 0,12427295 0,15364887 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,12427295 0,15356996 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,12427295 0,15349112 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,12427295 0,15341237 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,12427295 0,1533337 ! vesicle docking GO:0048278 47 24 0,000 0,12427295 0,15325511 ! spinal cord development GO:0021510 47 24 0,000 0,12427295 0,15317659 ! vacuole organization GO:0007033 43 24 0,000 0,12427295 0,15309816 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,12427295 0,15301981 ! digestive system process GO:0022600 39 24 0,000 0,12427295 0,15294154 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,12427295 0,15286335 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,12427295 0,15278524 ! regulation of behavior GO:0050795 43 24 0,000 0,12427295 0,15270721 ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,12427295 0,15262925 ! membrane depolarization GO:0051899 39 24 0,000 0,12427295 0,15255138 ! pallium development GO:0021543 49 24 0,000 0,12427295 0,15247359 ! pentose metabolic process GO:0019321 35 24 0,000 0,12427295 0,15239588 ! regulation of oxidoreductase activity GO:0051341 46 24 0,000 0,12427295 0,15231824 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,12427295 0,15224069 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,12427295 0,15216321 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,12427295 0,15208581 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,12427295 0,1520085 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,12427295 0,15193126 GO:0033013|tetrapyrrole metabolic process, ! regulation of multi-organism process GO:0043900 36 24 0,000 0,12427295 0,15185409 ! regulation of amine transport GO:0051952 40 24 0,000 0,12427295 0,15177701 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,12910366 0,15759686 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,12910366 0,15751694 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 0,000 0,12910366 0,15743711 ! sperm motility GO:0030317 31 25 0,000 0,12910366 0,15735735 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,12910366 0,15727768 ! receptor metabolic process GO:0043112 46 25 0,000 0,12910366 0,15719808 ! chromosome condensation GO:0030261 45 25 0,000 0,12910366 0,15711857 ! osteoblast differentiation GO:0001649 60 25 0,000 0,12910366 0,15703914 ! coenzyme catabolic process GO:0009109 39 25 0,000 0,12910366 0,15695978 ! regulation of insulin secretion GO:0050796 37 25 0,000 0,12910366 0,15688051 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,12910366 0,15680132 ! interaction with host GO:0051701 62 25 0,000 0,12910366 0,1567222 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,12910366 0,15664317 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,12910366 0,15656422 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,12910366 0,15648534 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 0,000 0,12910366 0,15640655 ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,12910366 0,15632784 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,12910366 0,1562492 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,12910366 0,15617064 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,12910366 0,15609217 ! telomere organization GO:0032200 43 25 0,000 0,12910366 0,15601377 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,12910366 0,15593545 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,12910366 0,1558572 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,13390789 0,16157592 ! embryonic pattern specification GO:0009880 44 26 0,000 0,13390789 0,16149493 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,13390789 0,16141402 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,13390789 0,16133319 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,13390789 0,16125244 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,13390789 0,16117178 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,13390789 0,16109119 ! molting cycle process GO:0022404 50 26 0,000 0,13390789 0,16101068 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,13390789 0,16093026 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,13390789 0,16084991 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,13390789 0,16076965 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,13390789 0,16068947 ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,13390789 0,16060936 ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,13390789 0,16052934 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,13390789 0,16044939 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,13390789 0,16036953 GO:0045840|positive regulation of mitosis, ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,13390789 0,16028974 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,13390789 0,16021003 ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,13390789 0,16013041 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,13390789 0,16005086 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,13868577 0,16567923 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,13868577 0,16559701 ! iron ion transport GO:0006826 59 27 0,000 0,13868577 0,16551486 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 0,000 0,13868577 0,1654328 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,13868577 0,16535083 ! protein amino acid acylation GO:0043543 55 27 0,000 0,13868577 0,16526893 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,13868577 0,16518711 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,13868577 0,16510538 ! fat cell differentiation GO:0045444 50 27 0,000 0,13868577 0,16502372 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,13868577 0,16494215 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,13868577 0,16486066 ! autophagy GO:0006914 41 27 0,000 0,13868577 0,16477924 ! male gonad development GO:0008584 44 27 0,000 0,13868577 0,16469791 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,13868577 0,16461666 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,13868577 0,16453549 ! glutathione metabolic process GO:0006749 39 27 0,000 0,13868577 0,16445439 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,13868577 0,16437338 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,13868577 0,16429245 ! circadian rhythm GO:0007623 50 28 0,000 0,14343746 0,16983785 ! dendrite development GO:0016358 59 28 0,000 0,14343746 0,16975431 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,14343746 0,16967085 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,14343746 0,16958748 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,14343746 0,16950418 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,14343746 0,16942097 ! lipid oxidation GO:0034440 43 28 0,000 0,14343746 0,16933784 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,14343746 0,16925479 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,14343746 0,16917182 ! translational initiation GO:0006413 65 29 0,000 0,14816308 0,17465966 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,14816308 0,17457413 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,14816308 0,17448868 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,14816308 0,17440331 ! catechol metabolic process GO:0009712 54 29 0,000 0,14816308 0,17431803 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,14816308 0,17423283 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,14816308 0,17414772 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,14816308 0,17406268 ! cell fate determination GO:0001709 60 29 0,000 0,14816308 0,17397773 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,14816308 0,17389287 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,14816308 0,17380808 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,14816308 0,17372338 ! regulation of coagulation GO:0050818 46 29 0,000 0,14816308 0,17363876 ! phenol metabolic process GO:0018958 55 30 0,000 0,15286279 0,17905934 ! zinc ion transport GO:0006829 45 30 0,000 0,15286279 0,17897221 ! membrane docking GO:0022406 61 30 0,000 0,15286279 0,17888516 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,15286279 0,17879819 ! cell junction assembly GO:0034329 78 30 0,000 0,15286279 0,17871131 ! regulation of innate immune response GO:0045088 51 30 0,000 0,15286279 0,17862452 ! acute-phase response GO:0006953 49 30 0,000 0,15286279 0,17853781 ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,15286279 0,17845118 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,15286279 0,17836464 ! phospholipid transport GO:0015914 51 30 0,000 0,15286279 0,17827818 ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,15286279 0,1781918 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,15286279 0,17810551 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,15286279 0,1780193 ! eye morphogenesis GO:0048592 60 30 0,000 0,15286279 0,17793318 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,15753673 0,183285 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,15753673 0,18319641 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,15753673 0,18310791 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,15753673 0,1830195 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,15753673 0,18293117 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,15753673 0,18284292 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,15753673 0,18275476 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,15753673 0,18266669 ! ovulation cycle process GO:0022602 49 31 0,000 0,15753673 0,1825787 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,15753673 0,18249079 ! peptide transport GO:0015833 55 31 0,000 0,15753673 0,18240297 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,15753673 0,18231524 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,15753673 0,18222759 ! mesoderm formation GO:0001707 69 31 0,000 0,15753673 0,18214002 ! natural killer cell activation GO:0030101 45 31 0,000 0,15753673 0,18205253 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,15753673 0,18196514 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,15753673 0,18187782 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,15753673 0,18179059 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,15753673 0,18170344 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,16218504 0,18697518 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,16218504 0,18688563 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,16218504 0,18679617 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,16218504 0,18670679 ! cholesterol transport GO:0030301 56 32 0,000 0,16218504 0,1866175 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,16218504 0,1865283 ! spliceosome assembly GO:0000245 67 32 0,000 0,16218504 0,18643918 ! spindle organization GO:0007051 46 32 0,000 0,16218504 0,18635014 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,16218504 0,18626119 ! metanephros development GO:0001656 74 32 0,000 0,16218504 0,18617233 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,16218504 0,18608355 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,16218504 0,18599485 ! regulation of protein import into nucleus GO:0042306 63 32 0,000 0,16218504 0,18590624 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,16218504 0,18581771 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,16218504 0,18572927 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,16218504 0,18564091 ! ovulation cycle GO:0042698 51 32 0,000 0,16218504 0,18555264 ! BMP signaling pathway GO:0030509 64 32 0,000 0,16218504 0,18546445 ! hindbrain development GO:0030902 61 32 0,000 0,16218504 0,18537634 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,16218504 0,18528832 ! gene silencing GO:0016458 65 32 0,000 0,16218504 0,18520038 ! post-embryonic development GO:0009791 69 33 0,000 0,16680785 0,19038884 ! protein targeting to membrane GO:0006612 68 33 0,000 0,16680785 0,19029857 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,16680785 0,19020838 ! ceramide metabolic process GO:0006672 64 33 0,000 0,16680785 0,19011828 ! formation of primary germ layer GO:0001704 72 33 0,000 0,16680785 0,19002826 ! cell fate specification GO:0001708 52 33 0,000 0,16680785 0,18993833 ! sterol transport GO:0015918 57 33 0,000 0,16680785 0,18984848 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,16680785 0,18975872 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,16680785 0,18966904 ! adult locomotory behavior GO:0008344 59 33 0,000 0,16680785 0,18957944 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,16680785 0,18948994 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,17140531 0,19462065 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,17140531 0,19452885 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,17140531 0,19443714 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,17140531 0,19434551 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,17140531 0,19425396 ! mismatch repair GO:0006298 46 34 0,000 0,17140531 0,19416251 ! spermatid development GO:0007286 63 34 0,000 0,17140531 0,19407114 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,17140531 0,19397985 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,17140531 0,19388865 ! placenta development GO:0001890 53 34 0,000 0,17140531 0,19379754 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 0,000 0,17140531 0,19370651 ! regulation of muscle development GO:0048634 70 35 0,000 0,17597755 0,19878027 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,17597755 0,19868699 ! negative regulation of secretion GO:0051048 63 35 0,000 0,17597755 0,1985938 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,17597755 0,19850069 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,17597755 0,19840767 ! odontogenesis GO:0042476 66 35 0,000 0,17597755 0,19831474 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,17597755 0,1982219 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,17597755 0,19812914 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,17597755 0,19803647 ! calcium-mediated signaling GO:0019722 62 35 0,000 0,17597755 0,19794389 ! cytokine production GO:0001816 59 35 0,000 0,17597755 0,19785139 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,17597755 0,19775898 ! vesicle localization GO:0051648 64 35 0,000 0,17597755 0,19766666 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,18052471 0,20267963 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,18052471 0,2025851 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,18052471 0,20249065 ! cell junction organization GO:0034330 86 36 0,000 0,18052471 0,20239629 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,18052471 0,20230203 ! positive regulation of cell development GO:0010720 80 36 0,000 0,18052471 0,20220784 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,18052471 0,20211375 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,18052471 0,20201974 ! aerobic respiration GO:0009060 55 36 0,000 0,18052471 0,20192582 ! androgen receptor signaling pathway GO:0030521 74 36 0,000 0,18052471 0,20183199 ! embryonic organ development GO:0048568 57 36 0,000 0,18052471 0,20173825 ! RNA export from nucleus GO:0006405 56 37 0,000 0,18504693 0,20669587 ! meiosis I GO:0007127 65 37 0,000 0,18504693 0,20659996 ! sister chromatid segregation GO:0000819 58 37 0,000 0,18504693 0,20650413 ! organic anion transport GO:0015711 68 37 0,000 0,18504693 0,2064084 ! tissue remodeling GO:0048771 76 37 0,000 0,18504693 0,20631275 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,18504693 0,20621719 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,18504693 0,20612172 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,18504693 0,20602633 ! regulation of protein stability GO:0031647 73 37 0,000 0,18504693 0,20593104 ! glycogen metabolic process GO:0005977 61 37 0,000 0,18504693 0,20583583 ! pigment metabolic process GO:0042440 80 37 0,000 0,18504693 0,20574072 ! spermatid differentiation GO:0048515 66 37 0,000 0,18504693 0,20564569 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,18954434 0,21054649 GO:0006956|complement activation, ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,18954434 0,21044932 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,18954434 0,21035225 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,18954434 0,21025527 ! carbohydrate homeostasis GO:0033500 53 38 0,000 0,18954434 0,21015838 GO:0042593|glucose homeostasis, ! lipid homeostasis GO:0055088 67 38 0,000 0,18954434 0,21006158 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,18954434 0,20996486 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,18954434 0,20986824 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,18954434 0,20977171 ! glucan metabolic process GO:0044042 62 38 0,000 0,18954434 0,20967526 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,19401709 0,21452441 ! organic ether metabolic process GO:0018904 55 39 0,000 0,19401709 0,21442586 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,19401709 0,21432741 ! segmentation GO:0035282 67 39 0,000 0,19401709 0,21422905 ! RNA modification GO:0009451 57 39 0,000 0,19401709 0,21413078 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,19846529 0,2189397 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,19846529 0,21883936 ! feeding behavior GO:0007631 59 40 0,000 0,19846529 0,21873912 ! negative regulation of binding GO:0051100 72 40 0,000 0,19846529 0,21863896 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,2028891 0,22341014 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,2028891 0,22330794 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,2028891 0,22320584 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,2028891 0,22310382 ! positive regulation of transcription factor activity GO:0051091 62 42 0,000 0,20728863 0,22783757 GO:0090047|positive regulation of transcription regulator activity, ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,20728863 0,22773354 ! regulation of tube size GO:0035150 71 42 0,000 0,20728863 0,2276296 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,20728863 0,22752575 ! neuron migration GO:0001764 79 42 0,000 0,20728863 0,227422 ! regulation of protein secretion GO:0050708 71 42 0,000 0,20728863 0,22731834 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,21166403 0,23201078 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,21166403 0,23190512 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,21166403 0,23179957 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,21166403 0,23169411 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,21166403 0,23158875 ! glucose transport GO:0015758 65 43 0,000 0,21166403 0,23148348 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,21166403 0,23137831 ! phagocytosis GO:0006909 90 43 0,000 0,21166403 0,23127323 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,21166403 0,23116825 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,21601542 0,23581357 ! hexose transport GO:0008645 67 44 0,000 0,21601542 0,23570662 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,21601542 0,23559977 ! male sex differentiation GO:0046661 76 44 0,000 0,21601542 0,23549302 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,22034294 0,24010195 ! glycolysis GO:0006096 65 45 0,000 0,22034294 0,23999326 ! leukocyte migration GO:0050900 68 45 0,000 0,22034294 0,23988467 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,22034294 0,23977617 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,22034294 0,23966777 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,22034294 0,23955947 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,22034294 0,23945127 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,22034294 0,23934317 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,22034294 0,23923516 ! cell growth GO:0016049 84 45 0,000 0,22034294 0,23912725 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,22464671 0,243688 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,22464671 0,24357818 ! positive regulation of protein transport GO:0051222 72 46 0,000 0,22464671 0,24346846 ! positive regulation of defense response GO:0031349 76 47 0,000 0,22892687 0,24799552 ! endosome transport GO:0016197 108 47 0,000 0,22892687 0,24788391 ! positive regulation of DNA binding GO:0043388 73 47 0,000 0,22892687 0,2477724 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,22892687 0,24766099 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,22892687 0,24754969 ! JNK cascade GO:0007254 91 47 0,000 0,22892687 0,24743848 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,22892687 0,24732737 ! protein homooligomerization GO:0051260 76 47 0,000 0,22892687 0,24721636 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,23318354 0,25170014 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,23318354 0,25158727 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,23318354 0,2514745 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,23318354 0,25136183 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,23741686 0,25581055 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,23741686 0,25569604 ! regulation of ion transport GO:0043269 77 49 0,000 0,23741686 0,25558164 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,23741686 0,25546733 ! peptide metabolic process GO:0006518 76 49 0,000 0,23741686 0,25535313 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,23741686 0,25523903 ! endocrine system development GO:0035270 104 49 0,000 0,23741686 0,25512504 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,23741686 0,25501114 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,23741686 0,25489735 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,24162694 0,2593017 ! neuromuscular process GO:0050905 99 50 0,000 0,24162694 0,2591861 ! regulation of ossification GO:0030278 117 50 0,000 0,24162694 0,2590706 ! inner ear development GO:0048839 79 50 0,000 0,24162694 0,2589552 ! histone modification GO:0016570 91 50 0,000 0,24162694 0,2588399 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,24162694 0,25872471 ! positive regulation of binding GO:0051099 78 51 0,000 0,24581392 0,26309088 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,24581392 0,2629739 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,24581392 0,26285702 ! excretion GO:0007588 83 51 0,000 0,24581392 0,26274025 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,24581392 0,26262358 ! chromatin remodeling GO:0006338 109 51 0,000 0,24581392 0,26250701 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,24997792 0,26683535 ! covalent chromatin modification GO:0016569 101 52 0,000 0,24997792 0,26671702 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,24997792 0,2665988 ! amino acid activation GO:0043038 92 52 0,000 0,24997792 0,26648068 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,24997792 0,26636266 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,25411907 0,27065537 ! RNA catabolic process GO:0006401 93 53 0,000 0,25411907 0,27053561 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,25411907 0,27041596 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,25411907 0,27029641 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,25411907 0,27017697 ! activation of phospholipase C activity GO:0007202 103 54 0,000 0,25823749 0,27443437 GO:0010863|positive regulation of phospholipase C activity, ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,25823749 0,27431321 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,25823749 0,27419215 ! cell recognition GO:0008037 85 54 0,000 0,25823749 0,2740712 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,25823749 0,27395036 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,25823749 0,27382962 ! chloride transport GO:0006821 90 55 0,000 0,26233331 0,2780502 ! glucose catabolic process GO:0006007 82 55 0,000 0,26233331 0,27792776 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,26233331 0,27780544 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,26233331 0,27768322 ! positive regulation of phospholipase activity GO:0010518 104 55 0,000 0,26233331 0,2775611 ! gastrulation GO:0007369 112 55 0,000 0,26233331 0,2774391 ! heart morphogenesis GO:0003007 97 55 0,000 0,26233331 0,2773172 ! RNA elongation GO:0006354 79 55 0,000 0,26233331 0,27719541 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,26233331 0,27707373 ! sensory perception of smell GO:0007608 80 56 0,000 0,26640665 0,28125248 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,26640665 0,28112912 ! regulation of bone remodeling GO:0046850 137 57 0,000 0,27045763 0,28527885 ! lipid modification GO:0030258 97 57 0,000 0,27045763 0,28515384 ! regulation of phospholipase activity GO:0010517 106 57 0,000 0,27045763 0,28502893 ! regulation of tissue remodeling GO:0034103 140 58 0,000 0,27448637 0,28914808 ! regulation of endocytosis GO:0030100 91 58 0,000 0,27448637 0,28902154 ! adult behavior GO:0030534 99 58 0,000 0,27448637 0,28889511 ! positive regulation of lipase activity GO:0060193 108 58 0,000 0,27448637 0,28876879 ! positive regulation of secretion GO:0051047 95 59 0,000 0,278493 0,29285584 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,278493 0,2927279 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,278493 0,29260007 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,278493 0,29247235 ! establishment of organelle localization GO:0051656 109 59 0,000 0,278493 0,29234475 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,28247764 0,29639825 ! regulation of heart contraction GO:0008016 110 60 0,000 0,28247764 0,29626905 ! camera-type eye development GO:0043010 116 60 0,000 0,28247764 0,29613995 ! kidney development GO:0001822 122 60 0,000 0,28247764 0,29601097 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,2864404 0,30003291 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,2864404 0,29990235 ! mesoderm development GO:0007498 119 61 0,000 0,2864404 0,2997719 ! tRNA processing GO:0008033 89 61 0,000 0,2864404 0,29964156 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,2864404 0,29951134 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,29038141 0,30350029 ! regulation of mitosis GO:0007088 105 63 0,000 0,29430078 0,30746316 GO:0051783|regulation of nuclear division, ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,29430078 0,30732972 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,29430078 0,30719638 ! steroid hormone receptor signaling pathway GO:0030518 129 63 0,000 0,29430078 0,30706317 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,29819863 0,31099519 ! cell redox homeostasis GO:0045454 102 64 0,000 0,29819863 0,31086044 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,29819863 0,31072581 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,29819863 0,3105913 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,29819863 0,3104569 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,30207508 0,31435668 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,30207508 0,31422077 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,30207508 0,31408498 GO:0035113|embryonic appendage morphogenesis, ! myeloid cell differentiation GO:0030099 111 65 0,000 0,30207508 0,31394931 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,30593025 0,31781873 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,30593025 0,31768156 ! extracellular matrix organization GO:0030198 133 66 0,000 0,30593025 0,31754451 ! secondary metabolic process GO:0019748 116 66 0,000 0,30593025 0,31740758 ! cell projection assembly GO:0030031 120 66 0,000 0,30593025 0,31727077 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,30976425 0,32110848 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,30976425 0,32097019 ! lung development GO:0030324 144 67 0,000 0,30976425 0,32083202 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,30976425 0,32069397 ! hexose catabolic process GO:0019320 104 67 0,000 0,30976425 0,32055604 ! adaptive immune response GO:0002250 119 67 0,000 0,30976425 0,32041822 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! amino acid transport GO:0006865 125 68 0,000 0,3135772 0,32422293 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,3135772 0,32408365 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 0,000 0,3135772 0,3239445 ! regulation of lipase activity GO:0060191 130 68 0,000 0,3135772 0,32380547 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,31736921 0,32758058 ! urogenital system development GO:0001655 137 69 0,000 0,31736921 0,32744011 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,31736921 0,32729976 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,31736921 0,32715952 ! antigen processing and presentation GO:0019882 104 69 0,000 0,31736921 0,32701941 ! appendage morphogenesis GO:0035107 135 70 0,000 0,3211404 0,33076362 GO:0035108|limb morphogenesis, ! respiratory tube development GO:0030323 150 70 0,000 0,3211404 0,33062208 ! amine catabolic process GO:0009310 117 71 0,000 0,32489088 0,33434023 ! appendage development GO:0048736 136 71 0,000 0,32489088 0,33419729 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,32489088 0,33405447 ! acute inflammatory response GO:0002526 113 72 0,000 0,32862077 0,33774522 ! phosphoinositide metabolic process GO:0030384 128 72 0,000 0,32862077 0,33760101 ! carbohydrate transport GO:0008643 110 72 0,000 0,32862077 0,33745692 ! respiratory system development GO:0060541 153 72 0,000 0,32862077 0,33731296 ! regulation of blood pressure GO:0008217 125 73 0,000 0,33233017 0,34097501 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,33233017 0,34082966 ! fertilization GO:0009566 90 73 0,000 0,33233017 0,34068444 ! regulation of transcription factor activity GO:0051090 126 74 0,000 0,3360192 0,3443195 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 126 74 0,000 0,3360192 0,34417292 ! neurotransmitter transport GO:0006836 123 74 0,000 0,3360192 0,34402647 ! exocytosis GO:0006887 133 74 0,000 0,3360192 0,34388013 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,3360192 0,34373393 ! eye development GO:0001654 143 74 0,000 0,3360192 0,34358784 ! organelle localization GO:0051640 136 74 0,000 0,3360192 0,34344188 ! cell-matrix adhesion GO:0007160 163 75 0,000 0,33968797 0,34704427 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,33968797 0,34689697 ! rhythmic process GO:0048511 128 75 0,000 0,33968797 0,34674979 ! defense response to bacterium GO:0042742 89 76 0,000 0,34333659 0,35032563 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,34333659 0,35017712 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,34333659 0,35002874 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,34696516 0,35357822 ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,35057381 0,3571044 ! negative regulation of organelle organization GO:0010639 161 78 0,000 0,35057381 0,35695328 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,35416264 0,36045487 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,35416264 0,36030246 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,35416264 0,36015017 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,35773175 0,36362594 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,35773175 0,36347238 ! inorganic anion transport GO:0015698 138 80 0,000 0,35773175 0,36331895 ! response to hypoxia GO:0001666 171 81 0,000 0,36128126 0,36676907 ! digestion GO:0007586 112 81 0,000 0,36128126 0,36661438 ! cell-substrate adhesion GO:0031589 171 81 0,000 0,36128126 0,36645983 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,36128126 0,3663054 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,36481127 0,36972869 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,36481127 0,36957301 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,36481127 0,36941747 ! response to oxygen levels GO:0070482 176 83 0,000 0,36832188 0,3728155 ! regulation of lyase activity GO:0051339 160 83 0,000 0,36832188 0,37265872 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,37181321 0,37603303 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,37181321 0,37587503 ! nucleosome assembly GO:0006334 122 85 0,000 0,37528536 0,37922577 ! amine biosynthetic process GO:0009309 138 86 0,000 0,37873843 0,38255443 ! chromatin assembly GO:0031497 124 86 0,000 0,37873843 0,3823939 ! amine transport GO:0015837 155 86 0,000 0,37873843 0,3822335 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,38217253 0,38553757 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,38217253 0,38537598 ! cellular respiration GO:0045333 135 88 0,000 0,38558776 0,38865695 ! regulation of DNA binding GO:0051101 155 88 0,000 0,38558776 0,3884942 ! regulation of neurological system process GO:0031644 148 88 0,000 0,38558776 0,38833158 ! cellular defense response GO:0006968 114 89 0,000 0,38898422 0,3915883 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,39236202 0,39482352 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,39236202 0,39465846 ! sterol metabolic process GO:0016125 152 91 0,000 0,39572126 0,39787102 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,39572126 0,39770483 ! regulation of defense response GO:0031347 149 92 0,000 0,39906204 0,4008949 ! nucleosome organization GO:0034728 138 92 0,000 0,39906204 0,40072758 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,39906204 0,4005604 ! vitamin metabolic process GO:0006766 139 92 0,000 0,39906204 0,40039336 ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,40238446 0,40355858 ! negative regulation of multicellular organismal process GO:0051241 166 93 0,000 0,40238446 0,40339043 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,40568863 0,40653346 ! female pregnancy GO:0007565 164 94 0,000 0,40568863 0,40636421 ! mRNA transport GO:0051028 169 96 0,000 0,41224257 0,41275723 ! hormone metabolic process GO:0042445 157 97 0,000 0,41549256 0,41583823 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,41872468 0,41889878 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,42193903 0,42193903