pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6763-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! release of cytochrome c from mitochondria GO:0001836 31 14 3,000 7,126E-07 1,741E-03 ! neural plate morphogenesis GO:0001839 7 5 2,000 1,422E-06 1,737E-03 ! neural plate development GO:0001840 9 6 2,000 2,833E-06 2,307E-03 ! apoptotic mitochondrial changes GO:0008637 42 20 3,000 3,365E-06 2,055E-03 ! induction of apoptosis by intracellular signals GO:0008629 95 45 4,000 3,935E-06 1,923E-03 ! male meiosis GO:0007140 9 8 2,000 7,871E-06 3,205E-03 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 2,000 7,871E-06 2,747E-03 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 3,000 8,607E-06 2,628E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 2,000 1,176E-05 3,192E-03 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 2,000 1,674E-05 4,088E-03 ! protein sumoylation GO:0016925 17 10 2,000 1,674E-05 3,717E-03 ! establishment of cell polarity GO:0030010 21 12 2,000 3,044E-05 6,198E-03 ! negative regulation of protein kinase activity GO:0006469 144 69 4,000 3,268E-05 6,142E-03 ! negative regulation of kinase activity GO:0033673 145 70 4,000 3,505E-05 6,116E-03 ! response to X-ray GO:0010165 28 13 2,000 3,942E-05 6,421E-03 ! negative regulation of transferase activity GO:0051348 155 74 4,000 4,586E-05 7,002E-03 ! regulation of S phase GO:0033261 26 14 2,000 4,998E-05 7,183E-03 ! response to gamma radiation GO:0010332 30 14 2,000 4,998E-05 6,783E-03 ! mammary gland development GO:0030879 93 40 3,000 5,846E-05 7,517E-03 ! cytokinesis GO:0000910 84 42 3,000 7,102E-05 8,675E-03 ! centrosome cycle GO:0007098 26 18 2,000 1,103E-04 0,01283385 ! neural crest cell migration GO:0001755 41 18 2,000 1,103E-04 0,0122505 ! regulation of DNA metabolic process GO:0051052 188 97 4,000 1,664E-04 0,01767643 ! synapse organization GO:0050808 102 53 3,000 1,776E-04 0,01807804 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 2,000 2,05E-04 0,02003251 ! cell aging GO:0007569 48 22 2,000 2,05E-04 0,01926203 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 3,000 2,052E-04 0,01856338 ! glycerol metabolic process GO:0006071 40 23 2,000 2,348E-04 0,02048959 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 3,000 2,357E-04 0,01985406 ! regulation of actin filament length GO:0030832 118 58 3,000 2,521E-04 0,02052969 ! positive regulation of cytoskeleton organization GO:0051495 52 24 2,000 2,673E-04 0,02106882 ! negative regulation of phosphorylation GO:0042326 52 24 2,000 2,673E-04 0,02041042 ! 2-oxoglutarate metabolic process GO:0006103 10 5 1,000 2,725E-04 0,0201705 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 1,000 2,725E-04 0,01957725 ! Notch receptor processing GO:0007220 11 5 1,000 2,725E-04 0,0190179 ! negative regulation of survival gene product expression GO:0008634 9 5 1,000 2,725E-04 0,01848962 ! valine metabolic process GO:0006573 12 5 1,000 2,725E-04 0,0179899 ! polyol catabolic process GO:0046174 9 5 1,000 2,725E-04 0,01751648 GO:0019405|alditol catabolic process, ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 1,000 2,725E-04 0,01706734 ! negative regulation of T cell mediated immunity GO:0002710 15 5 1,000 2,725E-04 0,01664066 GO:0002707|negative regulation of lymphocyte mediated immunity, ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 1,000 2,725E-04 0,01623479 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 1,000 2,725E-04 0,01584825 ! inner cell mass cell proliferation GO:0001833 5 5 1,000 2,725E-04 0,01547968 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 1,000 2,725E-04 0,01512787 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of DNA replication GO:0008156 45 25 2,000 3,026E-04 0,01642955 ! regulation of cellular component size GO:0032535 125 61 3,000 3,063E-04 0,0162675 ! DNA damage response, signal transduction GO:0042770 136 62 3,000 3,261E-04 0,01694991 ! microtubule organizing center organization GO:0031023 42 26 2,000 3,408E-04 0,0173445 GO:0051297|centrosome organization, ! negative regulation of phosphorus metabolic process GO:0010563 56 26 2,000 3,408E-04 0,01699053 GO:0045936|negative regulation of phosphate metabolic process, ! neural crest cell development GO:0014032 59 26 2,000 3,408E-04 0,01665072 GO:0014033|neural crest cell differentiation, ! alditol metabolic process GO:0019400 44 26 2,000 3,408E-04 0,01632423 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 1,000 4,073E-04 0,01913422 ! activation of MAPKKK activity GO:0000185 12 6 1,000 4,073E-04 0,01877319 ! thymic T cell selection GO:0045061 16 6 1,000 4,073E-04 0,01842554 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 1,000 4,073E-04 0,01809053 ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 1,000 4,073E-04 0,01776749 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! response to UV-C GO:0010225 14 6 1,000 4,073E-04 0,01745578 ! negative regulation of neuroblast proliferation GO:0007406 25 6 1,000 4,073E-04 0,01715482 ! primary neural tube formation GO:0014020 61 29 2,000 4,734E-04 0,01960229 ! regulation of actin filament depolymerization GO:0030834 67 30 2,000 5,24E-04 0,02133467 ! regulation of helicase activity GO:0051095 16 7 1,000 5,682E-04 0,02275648 ! cytokinesis during cell cycle GO:0033205 14 7 1,000 5,682E-04 0,02238944 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 5,682E-04 0,02203405 ! oxaloacetate metabolic process GO:0006107 13 7 1,000 5,682E-04 0,02168977 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 1,000 5,682E-04 0,02135608 ! amyloid precursor protein catabolic process GO:0042987 15 7 1,000 5,682E-04 0,0210325 ! positive regulation of isotype switching GO:0045830 17 7 1,000 5,682E-04 0,02071859 GO:0045911|positive regulation of DNA recombination, ! vesicle fusion GO:0006906 20 7 1,000 5,682E-04 0,0204139 ! positive regulation of mitotic cell cycle GO:0045931 14 7 1,000 5,682E-04 0,02011805 ! centrosome duplication GO:0051298 14 7 1,000 5,682E-04 0,01983065 ! G1 DNA damage checkpoint GO:0031571 20 7 1,000 5,682E-04 0,01955134 ! anterograde axon cargo transport GO:0008089 18 7 1,000 5,682E-04 0,0192798 ! B cell lineage commitment GO:0002326 21 7 1,000 5,682E-04 0,01901569 ! T cell lineage commitment GO:0002360 16 7 1,000 5,682E-04 0,01875872 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 1,000 5,682E-04 0,0185086 GO:0002714|positive regulation of B cell mediated immunity, ! coenzyme A metabolic process GO:0015936 12 7 1,000 5,682E-04 0,01826507 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 1,000 5,682E-04 0,01802786 ! actin filament organization GO:0007015 167 72 3,000 5,773E-04 0,01808133 ! regulation of caspase activity GO:0043281 136 74 3,000 6,404E-04 0,01980423 ! axon guidance GO:0007411 162 75 3,000 6,737E-04 0,02057429 ! response to ionizing radiation GO:0010212 74 33 2,000 6,96E-04 0,02099259 ! regulation of actin cytoskeleton organization GO:0032956 167 76 3,000 7,083E-04 0,0211013 ! regulation of endopeptidase activity GO:0052548 141 77 3,000 7,44E-04 0,0218998 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 1,000 7,55E-04 0,02195775 ! regulation of lipid kinase activity GO:0043550 17 8 1,000 7,55E-04 0,02169942 ! succinate metabolic process GO:0006105 17 8 1,000 7,55E-04 0,02144711 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 1,000 7,55E-04 0,02120059 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 7,55E-04 0,02095967 ! ER overload response GO:0006983 13 8 1,000 7,55E-04 0,02072417 ! regulation of T cell differentiation in the thymus GO:0033081 14 8 1,000 7,55E-04 0,0204939 ! response to tumor cell GO:0002347 16 8 1,000 7,55E-04 0,02026869 ! ATP catabolic process GO:0006200 11 8 1,000 7,55E-04 0,02004838 ! blastocyst growth GO:0001832 19 8 1,000 7,55E-04 0,01983281 ! B cell receptor signaling pathway GO:0050853 22 8 1,000 7,55E-04 0,01962182 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 1,000 7,55E-04 0,01941527 ! regulation of actin filament-based process GO:0032970 170 79 3,000 8,194E-04 0,02085121 ! negative regulation of DNA metabolic process GO:0051053 65 35 2,000 8,285E-04 0,02086702 ! negative regulation of hydrolase activity GO:0051346 66 36 2,000 9,004E-04 0,02244492 ! regulation of peptidase activity GO:0052547 150 82 3,000 9,422E-04 0,02325107 ! middle ear morphogenesis GO:0042474 14 9 1,000 9,673E-04 0,02363229 ! amyloid precursor protein metabolic process GO:0042982 18 9 1,000 9,673E-04 0,0233983 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 1,000 9,673E-04 0,02316891 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! T cell selection GO:0045058 27 9 1,000 9,673E-04 0,02294397 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 1,000 9,673E-04 0,02272335 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 1,000 9,673E-04 0,02250694 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 1,000 9,673E-04 0,02229461 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 1,000 9,673E-04 0,02208625 GO:0002820|negative regulation of adaptive immune response, ! regulation of telomere maintenance GO:0032204 17 9 1,000 9,673E-04 0,02188175 ! neural tube formation GO:0001841 79 38 2,000 1,056E-03 0,02365943 ! cellular response to hormone stimulus GO:0032870 182 85 3,000 1,077E-03 0,02393029 ! mitochondrion organization GO:0007005 159 87 3,000 1,175E-03 0,02585852 ! positive regulation of B cell proliferation GO:0030890 18 10 1,000 1,205E-03 0,02628406 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 1,000 1,205E-03 0,02605146 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 1,000 1,205E-03 0,02582294 ! phosphagen metabolic process GO:0006599 17 10 1,000 1,205E-03 0,02559839 GO:0006600|creatine metabolic process, ! multicellular organism growth GO:0035264 19 10 1,000 1,205E-03 0,02537771 ! motor axon guidance GO:0008045 22 10 1,000 1,205E-03 0,02516081 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 1,000 1,205E-03 0,02494758 ! regulation of B cell differentiation GO:0045577 24 10 1,000 1,205E-03 0,02473794 ! negative regulation of immune effector process GO:0002698 23 10 1,000 1,205E-03 0,02453179 ! Rho protein signal transduction GO:0007266 88 40 2,000 1,227E-03 0,02476941 ! establishment or maintenance of cell polarity GO:0007163 96 41 2,000 1,319E-03 0,02640384 ! mesenchymal cell development GO:0014031 94 41 2,000 1,319E-03 0,02618917 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! embryonic epithelial tube formation GO:0001838 85 41 2,000 1,319E-03 0,02597797 ! gland development GO:0048732 220 91 3,000 1,388E-03 0,02712573 ! T cell differentiation GO:0030217 93 42 2,000 1,415E-03 0,02742629 ! regulation of T cell differentiation GO:0045580 78 42 2,000 1,415E-03 0,02721033 ! detection of mechanical stimulus GO:0050982 22 11 1,000 1,468E-03 0,02801213 ! keratinocyte proliferation GO:0043616 19 11 1,000 1,468E-03 0,02779498 ! negative regulation of proteolysis GO:0045861 25 11 1,000 1,468E-03 0,02758117 ! regulation of intracellular pH GO:0051453 21 11 1,000 1,468E-03 0,02737063 ! positive regulation of T cell mediated immunity GO:0002711 26 11 1,000 1,468E-03 0,02716327 ! purine ribonucleotide catabolic process GO:0009154 17 11 1,000 1,468E-03 0,02695904 ! nitric oxide metabolic process GO:0046209 17 11 1,000 1,468E-03 0,02675785 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 1,000 1,468E-03 0,02655964 GO:0006305|DNA alkylation, ! regulation of isotype switching GO:0045191 24 11 1,000 1,468E-03 0,02636435 ! apical protein localization GO:0045176 18 11 1,000 1,468E-03 0,02617191 ! oocyte development GO:0048599 20 11 1,000 1,468E-03 0,02598226 ! lysogeny GO:0030069 22 11 1,000 1,468E-03 0,02579534 GO:0019047|provirus integration, ! T cell receptor signaling pathway GO:0050852 29 11 1,000 1,468E-03 0,02561109 ! regulation of embryonic development GO:0045995 35 11 1,000 1,468E-03 0,02542945 ! positive regulation of MAP kinase activity GO:0043406 174 93 3,000 1,504E-03 0,02587409 ! regulation of T cell proliferation GO:0042129 80 43 2,000 1,515E-03 0,02587834 ! double-strand break repair GO:0006302 85 44 2,000 1,619E-03 0,02747297 ! regulation of epithelial cell proliferation GO:0050678 122 45 2,000 1,728E-03 0,02911994 ! polyol metabolic process GO:0019751 77 45 2,000 1,728E-03 0,02892049 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 1,000 1,755E-03 0,02916862 ! regulation of B cell proliferation GO:0030888 22 12 1,000 1,755E-03 0,02897154 ! T cell proliferation GO:0042098 32 12 1,000 1,755E-03 0,0287771 ! oligodendrocyte differentiation GO:0048709 17 12 1,000 1,755E-03 0,02858525 ! oocyte differentiation GO:0009994 21 12 1,000 1,755E-03 0,02839595 ! negative regulation of mast cell proliferation GO:0070667 24 12 1,000 1,755E-03 0,02820913 GO:0042130|negative regulation of T cell proliferation, ! pigmentation GO:0043473 103 46 2,000 1,842E-03 0,02940926 ! neural tube development GO:0021915 91 47 2,000 1,96E-03 0,03109053 ! double-strand break repair via homologous recombination GO:0000724 19 13 1,000 2,067E-03 0,03257983 GO:0000725|recombinational repair, ! organelle fusion GO:0048284 36 13 1,000 2,067E-03 0,03237099 ! positive regulation of cell growth GO:0030307 24 13 1,000 2,067E-03 0,03216481 ! ribonucleotide catabolic process GO:0009261 21 13 1,000 2,067E-03 0,03196123 ! cellular carbohydrate catabolic process GO:0044275 17 13 1,000 2,067E-03 0,03176022 ! asymmetric protein localization GO:0008105 24 13 1,000 2,067E-03 0,03156172 ! membrane protein proteolysis GO:0033619 33 13 1,000 2,067E-03 0,03136568 GO:0006509|membrane protein ectodomain proteolysis, ! nucleoside triphosphate catabolic process GO:0009143 22 13 1,000 2,067E-03 0,03117206 ! JAK-STAT cascade GO:0007259 82 48 2,000 2,082E-03 0,03121178 ! detection of stimulus involved in sensory perception GO:0050906 75 49 2,000 2,21E-03 0,0329177 ! regulation of lymphocyte differentiation GO:0045619 92 49 2,000 2,21E-03 0,03271819 ! regulation of mast cell proliferation GO:0070666 89 49 2,000 2,21E-03 0,0325211 ! activation of caspase activity GO:0006919 95 50 2,000 2,342E-03 0,03425771 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 1,000 2,403E-03 0,03494744 ! negative regulation of caspase activity GO:0043154 23 14 1,000 2,403E-03 0,03474065 ! bone mineralization GO:0030282 18 14 1,000 2,403E-03 0,03453629 ! T cell differentiation in the thymus GO:0033077 37 14 1,000 2,403E-03 0,03433433 ! regulation of cellular pH GO:0030641 27 14 1,000 2,403E-03 0,03413471 ! detection of abiotic stimulus GO:0009582 80 51 2,000 2,479E-03 0,03500156 ! negative regulation of immune system process GO:0002683 101 51 2,000 2,479E-03 0,0348004 ! response to estrogen stimulus GO:0043627 98 52 2,000 2,62E-03 0,03657909 ! Notch signaling pathway GO:0007219 111 52 2,000 2,62E-03 0,03637125 ! regulation of protein complex disassembly GO:0043244 127 52 2,000 2,62E-03 0,03616577 ! morphogenesis of embryonic epithelium GO:0016331 106 52 2,000 2,62E-03 0,03596259 ! regulation of mRNA processing GO:0050684 26 15 1,000 2,763E-03 0,03771529 ! glycoprotein catabolic process GO:0006516 33 15 1,000 2,763E-03 0,03750576 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 1,000 2,763E-03 0,03729854 ! G1/S transition checkpoint GO:0031575 37 15 1,000 2,763E-03 0,03709361 ! regulation of T cell mediated immunity GO:0002709 36 15 1,000 2,763E-03 0,03689091 ! synaptic transmission, cholinergic GO:0007271 24 15 1,000 2,763E-03 0,03669041 ! actin filament polymerization GO:0030041 27 15 1,000 2,763E-03 0,03649209 ! positive regulation of growth GO:0045927 96 53 2,000 2,767E-03 0,0363408 ! regulation of leukocyte proliferation GO:0070663 97 53 2,000 2,767E-03 0,03614646 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! epithelial tube morphogenesis GO:0060562 114 54 2,000 2,918E-03 0,03792313 ! response to UV GO:0009411 120 55 2,000 3,075E-03 0,03974578 ! positive regulation of cell size GO:0045793 29 16 1,000 3,147E-03 0,04046759 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 1,000 3,147E-03 0,04025571 ! heterophilic cell adhesion GO:0007157 43 16 1,000 3,147E-03 0,04004605 ! intermediate filament-based process GO:0045103 36 16 1,000 3,147E-03 0,03983856 ! negative regulation of immune response GO:0050777 38 16 1,000 3,147E-03 0,0396332 ! axon cargo transport GO:0008088 46 16 1,000 3,147E-03 0,03942996 ! biomineral formation GO:0031214 22 16 1,000 3,147E-03 0,03922878 ! neuromuscular synaptic transmission GO:0007274 34 16 1,000 3,147E-03 0,03902965 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 1,000 3,147E-03 0,03883253 ! negative regulation of leukocyte proliferation GO:0070664 32 16 1,000 3,147E-03 0,03863739 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 3,147E-03 0,03844421 ! regulation of protein catabolic process GO:0042176 126 56 2,000 3,236E-03 0,03933696 ! regulation of DNA replication GO:0006275 105 56 2,000 3,236E-03 0,03914223 ! positive regulation of caspase activity GO:0043280 108 57 2,000 3,403E-03 0,04095569 GO:0010952|positive regulation of peptidase activity, ! nucleotide-excision repair GO:0006289 91 57 2,000 3,403E-03 0,04075493 ! positive regulation of cell killing GO:0031343 36 17 1,000 3,555E-03 0,04236077 ! negative regulation of peptidase activity GO:0010466 28 17 1,000 3,555E-03 0,04215514 ! activation of MAPKK activity GO:0000186 43 17 1,000 3,555E-03 0,04195149 ! regulation of survival gene product expression GO:0045884 38 17 1,000 3,555E-03 0,0417498 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 1,000 3,555E-03 0,04155004 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 1,000 3,555E-03 0,04135218 GO:0002712|regulation of B cell mediated immunity, ! branched chain family amino acid metabolic process GO:0009081 37 17 1,000 3,555E-03 0,0411562 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 1,000 3,555E-03 0,04096207 ! aging GO:0007568 112 58 2,000 3,575E-03 0,04100424 ! positive regulation of organelle organization GO:0010638 108 58 2,000 3,575E-03 0,04081263 ! DNA integration GO:0015074 32 18 1,000 3,985E-03 0,04528263 ! negative regulation of protein catabolic process GO:0042177 42 18 1,000 3,985E-03 0,04507298 ! regulation of immunoglobulin production GO:0002637 49 18 1,000 3,985E-03 0,04486527 ! defense response to virus GO:0051607 43 18 1,000 3,985E-03 0,04465947 ! regulation of homeostatic process GO:0032844 148 62 2,000 4,315E-03 0,04813726 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 1,000 4,439E-03 0,04928928 ! neuromuscular junction development GO:0007528 43 19 1,000 4,439E-03 0,04906625 ! cellular pigmentation GO:0033059 37 19 1,000 4,439E-03 0,04884523 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 1,000 4,439E-03 0,0486262 ! skin development GO:0043588 42 20 1,000 4,915E-03 0,05360258 ! response to alkaloid GO:0043279 38 20 1,000 4,915E-03 0,05336435 ! purine nucleotide catabolic process GO:0006195 32 20 1,000 4,915E-03 0,05312822 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 1,000 4,915E-03 0,05289418 ! negative regulation of T cell activation GO:0050868 41 20 1,000 4,915E-03 0,05266218 ! negative regulation of cell growth GO:0030308 142 67 2,000 5,362E-03 0,0572042 ! activation of MAPK activity GO:0000187 124 67 2,000 5,362E-03 0,05695548 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 2,000 5,362E-03 0,05670892 ! regulation of cell killing GO:0031341 46 21 1,000 5,413E-03 0,05700502 ! cell structure disassembly during apoptosis GO:0006921 32 21 1,000 5,413E-03 0,05676037 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 1,000 5,413E-03 0,0565178 ! negative regulation of intracellular transport GO:0032387 44 21 1,000 5,413E-03 0,0562773 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 1,000 5,413E-03 0,05603884 ! negative regulation of ligase activity GO:0051352 116 68 2,000 5,588E-03 0,05760333 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! detection of external stimulus GO:0009581 102 68 2,000 5,588E-03 0,0573613 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 2,000 5,588E-03 0,05712129 ! negative regulation of cell size GO:0045792 144 69 2,000 5,82E-03 0,05924167 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 2,000 5,82E-03 0,05899585 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 2,000 5,82E-03 0,05875207 ! positive regulation of protein catabolic process GO:0045732 44 22 1,000 5,934E-03 0,05966091 ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 1,000 5,934E-03 0,0594164 ! microtubule-based transport GO:0010970 59 22 1,000 5,934E-03 0,05917388 ! cellular response to starvation GO:0009267 37 22 1,000 5,934E-03 0,05893334 ! actin polymerization or depolymerization GO:0008154 52 22 1,000 5,934E-03 0,05869474 ! apoptotic nuclear changes GO:0030262 34 22 1,000 5,934E-03 0,05845807 ! positive regulation of adaptive immune response GO:0002821 42 22 1,000 5,934E-03 0,0582233 ! sarcomere organization GO:0045214 32 22 1,000 5,934E-03 0,0579904 ! positive regulation of B cell activation GO:0050871 42 22 1,000 5,934E-03 0,05775937 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 1,000 6,477E-03 0,0627924 ! gluconeogenesis GO:0006094 38 23 1,000 6,477E-03 0,06254421 ! regulation of DNA recombination GO:0000018 51 23 1,000 6,477E-03 0,06229798 ! activation of pro-apoptotic gene products GO:0008633 51 23 1,000 6,477E-03 0,06205367 ! cellular response to reactive oxygen species GO:0034614 35 23 1,000 6,477E-03 0,06181127 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 1,000 6,477E-03 0,06157076 ! DNA modification GO:0006304 36 23 1,000 6,477E-03 0,06133211 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 2,000 6,549E-03 0,06177457 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 2,000 6,549E-03 0,06153698 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 1,000 7,042E-03 0,06591121 ! positive regulation of cell adhesion GO:0045785 61 24 1,000 7,042E-03 0,06565964 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 1,000 7,042E-03 0,06540999 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 1,000 7,042E-03 0,06516222 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 1,000 7,042E-03 0,06491633 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! purine ribonucleoside metabolic process GO:0046128 38 24 1,000 7,042E-03 0,06467228 GO:0042278|purine nucleoside metabolic process, ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 1,000 7,042E-03 0,06443006 GO:0002708|positive regulation of lymphocyte mediated immunity, ! oogenesis GO:0048477 44 24 1,000 7,042E-03 0,06418965 ! negative regulation of catabolic process GO:0009895 52 24 1,000 7,042E-03 0,06395103 ! lymphocyte differentiation GO:0030098 193 76 2,000 7,603E-03 0,06878958 ! protein import into nucleus, translocation GO:0000060 51 25 1,000 7,628E-03 0,06876175 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 1,000 7,628E-03 0,06850895 ! leukocyte adhesion GO:0007159 55 25 1,000 7,628E-03 0,068258 ! dicarboxylic acid metabolic process GO:0043648 48 25 1,000 7,628E-03 0,06800889 ! phototransduction GO:0007602 37 25 1,000 7,628E-03 0,06776158 ! regulation of alpha-beta T cell activation GO:0046634 48 25 1,000 7,628E-03 0,06751607 ! lymphocyte proliferation GO:0046651 55 25 1,000 7,628E-03 0,06727233 ! immunoglobulin production GO:0002377 62 25 1,000 7,628E-03 0,06703034 GO:0002440|production of molecular mediator of immune response, ! protein tetramerization GO:0051262 57 25 1,000 7,628E-03 0,06679009 ! positive regulation of ligase activity GO:0051351 130 77 2,000 7,881E-03 0,0687588 ! regulation of catabolic process GO:0009894 173 77 2,000 7,881E-03 0,0685141 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 1,000 8,235E-03 0,07134017 ! myelination GO:0042552 50 26 1,000 8,235E-03 0,07108808 ! initiation of viral infection GO:0019059 60 26 1,000 8,235E-03 0,07083777 ! pyruvate metabolic process GO:0006090 43 26 1,000 8,235E-03 0,07058922 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 1,000 8,235E-03 0,0703424 ! response to endoplasmic reticulum stress GO:0034976 46 26 1,000 8,235E-03 0,07009731 ! negative regulation of cell development GO:0010721 83 26 1,000 8,235E-03 0,06985391 GO:0050768|negative regulation of neurogenesis, ! response to estradiol stimulus GO:0032355 43 26 1,000 8,235E-03 0,0696122 ! positive regulation of MAPKKK cascade GO:0043410 50 26 1,000 8,235E-03 0,06937216 ! blastocyst development GO:0001824 50 26 1,000 8,235E-03 0,06913377 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 2,000 8,455E-03 0,07073484 ! response to steroid hormone stimulus GO:0048545 147 79 2,000 8,455E-03 0,07049342 ! activation of protein kinase activity GO:0032147 170 80 2,000 8,751E-03 0,07271271 ! insulin receptor signaling pathway GO:0008286 66 27 1,000 8,863E-03 0,07339906 ! mitochondrial membrane organization GO:0007006 60 27 1,000 8,863E-03 0,07315109 ! response to starvation GO:0042594 47 27 1,000 8,863E-03 0,07290479 ! response to toxin GO:0009636 49 27 1,000 8,863E-03 0,07266014 ! cellular response to oxidative stress GO:0034599 43 27 1,000 8,863E-03 0,07241713 ! regulation of chromosome organization GO:0033044 49 27 1,000 8,863E-03 0,07217574 ! cellular response to nutrient levels GO:0031669 45 27 1,000 8,863E-03 0,07193595 ! leukocyte proliferation GO:0070661 59 27 1,000 8,863E-03 0,07169776 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 55 27 1,000 8,863E-03 0,07146113 ! meiosis GO:0007126 143 81 2,000 9,052E-03 0,07274734 GO:0051327|M phase of meiotic cell cycle, ! meiotic cell cycle GO:0051321 144 82 2,000 9,36E-03 0,07497573 ! regulation of fibroblast proliferation GO:0048145 56 28 1,000 9,512E-03 0,07594198 ! neuron fate commitment GO:0048663 52 28 1,000 9,512E-03 0,07569461 ! negative regulation of protein modification process GO:0031400 66 28 1,000 9,512E-03 0,07544885 ! base-excision repair GO:0006284 41 28 1,000 9,512E-03 0,07520468 ! positive regulation of T cell differentiation GO:0045582 48 28 1,000 9,512E-03 0,07496208 ! peptidyl-tyrosine modification GO:0018212 57 28 1,000 9,512E-03 0,07472105 ! group transfer coenzyme metabolic process GO:0006752 53 28 1,000 9,512E-03 0,07448156 ! response to drug GO:0042493 149 83 2,000 9,675E-03 0,07551058 ! T cell activation GO:0042110 189 84 2,000 9,995E-03 0,07776079 ! regulation of ligase activity GO:0051340 147 84 2,000 9,995E-03 0,07751393 ! cellular iron ion homeostasis GO:0006879 57 29 1,000 0,01018171 0,07871496 ! ER-nuclear signaling pathway GO:0006984 52 29 1,000 0,01018171 0,07846665 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 1,000 0,01018171 0,0782199 ! response to organic cyclic substance GO:0014070 58 29 1,000 0,01018171 0,0779747 ! synaptogenesis GO:0007416 46 29 1,000 0,01018171 0,07773103 ! negative regulation of neuron differentiation GO:0045665 46 29 1,000 0,01018171 0,07748887 ! negative regulation of growth GO:0045926 168 85 2,000 0,01032087 0,07830399 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 1,000 0,01087155 0,08222664 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! myofibril assembly GO:0030239 50 30 1,000 0,01087155 0,08197285 GO:0055002|striated muscle cell development, ! immune response-activating signal transduction GO:0002757 58 30 1,000 0,01087155 0,08172063 GO:0002764|immune response-regulating signal transduction, ! positive regulation of multicellular organism growth GO:0040018 55 30 1,000 0,01087155 0,08146995 ! tissue homeostasis GO:0001894 50 30 1,000 0,01087155 0,0812208 GO:0048871|multicellular organismal homeostasis, ! regulation of B cell activation GO:0050864 55 30 1,000 0,01087155 0,08097318 ! iron ion homeostasis GO:0055072 60 31 1,000 0,01158146 0,08599851 ! detection of light stimulus GO:0009583 44 31 1,000 0,01158146 0,08573791 ! cellular response to extracellular stimulus GO:0031668 52 31 1,000 0,01158146 0,08547888 ! ensheathment of neurons GO:0007272 64 31 1,000 0,01158146 0,08522141 GO:0008366|axon ensheathment, ! negative regulation of leukocyte activation GO:0002695 60 31 1,000 0,01158146 0,08496549 ! response to heat GO:0009408 54 31 1,000 0,01158146 0,08471111 ! positive regulation of immune effector process GO:0002699 78 31 1,000 0,01158146 0,08445824 ! tube morphogenesis GO:0035239 194 89 2,000 0,01168729 0,08497632 ! regulation of cell cycle process GO:0010564 161 90 2,000 0,01204436 0,08731264 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 1,000 0,01231121 0,08898311 ! positive regulation of T cell proliferation GO:0042102 60 32 1,000 0,01231121 0,08872062 ! response to mechanical stimulus GO:0009612 60 32 1,000 0,01231121 0,08845968 ! muscle cell development GO:0055001 52 32 1,000 0,01231121 0,08820026 ! hexose biosynthetic process GO:0019319 53 32 1,000 0,01231121 0,08794237 ! peripheral nervous system development GO:0007422 68 32 1,000 0,01231121 0,08768598 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 1,000 0,01231121 0,08743108 ! positive regulation of catabolic process GO:0009896 72 32 1,000 0,01231121 0,08717765 ! regulation of cell adhesion GO:0030155 241 92 2,000 0,01277717 0,09021565 ! regulation of pH GO:0006885 56 33 1,000 0,01306058 0,09195099 ! positive regulation of gene-specific transcription GO:0043193 70 33 1,000 0,01306058 0,09168676 ! negative regulation of protein transport GO:0051224 74 33 1,000 0,01306058 0,09142405 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 2,000 0,01315294 0,09180752 GO:0010498|proteasomal protein catabolic process, ! glial cell differentiation GO:0010001 67 34 1,000 0,01382934 0,09625376 ! regulation of T cell activation GO:0050863 175 96 2,000 0,01431791 0,09937117 ! DNA damage checkpoint GO:0000077 78 35 1,000 0,01461726 0,10116141 ! leukocyte differentiation GO:0002521 232 98 2,000 0,01512606 0,10438687 ! interphase of mitotic cell cycle GO:0051329 224 98 2,000 0,01512606 0,10409283 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 1,000 0,01542414 0,105846 ! regulation of proteolysis GO:0030162 77 36 1,000 0,01542414 0,10554951 ! monosaccharide biosynthetic process GO:0046364 57 36 1,000 0,01542414 0,10525468 ! xenobiotic metabolic process GO:0006805 55 37 1,000 0,01624975 0,11057975 ! actomyosin structure organization GO:0031032 68 37 1,000 0,01624975 0,11027258 ! maintenance of protein location in cell GO:0032507 89 37 1,000 0,01624975 0,10996712 ! female gonad development GO:0008585 71 37 1,000 0,01624975 0,10966334 ! negative regulation of cell activation GO:0050866 69 37 1,000 0,01624975 0,10936124 ! positive regulation of DNA metabolic process GO:0051054 77 38 1,000 0,01709386 0,11472613 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 1,000 0,01709386 0,11441181 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 1,000 0,01709386 0,11409921 ! DNA integrity checkpoint GO:0031570 82 38 1,000 0,01709386 0,11378831 ! cellular response to insulin stimulus GO:0032869 85 38 1,000 0,01709386 0,1134791 ! mitotic cell cycle checkpoint GO:0007093 76 39 1,000 0,01795628 0,11888127 ! regulation of lymphocyte mediated immunity GO:0002706 79 39 1,000 0,01795628 0,11855997 ! nucleotide catabolic process GO:0009166 70 39 1,000 0,01795628 0,11824041 ! positive regulation of leukocyte proliferation GO:0070665 70 39 1,000 0,01795628 0,11792255 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! learning GO:0007612 82 40 1,000 0,01883678 0,12337332 ! development of primary female sexual characteristics GO:0046545 80 40 1,000 0,01883678 0,12304344 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 73 40 1,000 0,01883678 0,12271533 ! regulation of action potential in neuron GO:0019228 80 40 1,000 0,01883678 0,12238896 ! cellular amide metabolic process GO:0043603 73 41 1,000 0,01973515 0,12788585 ! gliogenesis GO:0042063 91 41 1,000 0,01973515 0,12754753 ! multicellular organismal metabolic process GO:0044236 64 41 1,000 0,01973515 0,12721099 ! monovalent inorganic cation homeostasis GO:0055067 72 41 1,000 0,01973515 0,12687622 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 1,000 0,01973515 0,12654321 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 95 41 1,000 0,01973515 0,12621195 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 1,000 0,02065118 0,1317254 ! ear morphogenesis GO:0042471 64 42 1,000 0,02065118 0,13138236 ! alcohol biosynthetic process GO:0046165 65 42 1,000 0,02065118 0,13104111 ! regulation of intracellular protein transport GO:0033157 86 42 1,000 0,02065118 0,13070163 ! ribonucleoside metabolic process GO:0009119 64 42 1,000 0,02065118 0,1303639 ! regulation of leukocyte mediated immunity GO:0002703 84 42 1,000 0,02065118 0,13002791 ! response to xenobiotic stimulus GO:0009410 63 42 1,000 0,02065118 0,12969364 ! calcium-dependent cell-cell adhesion GO:0016339 56 43 1,000 0,02158466 0,13520853 ! striated muscle cell differentiation GO:0051146 91 43 1,000 0,02158466 0,13486273 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 1,000 0,02158466 0,13451869 ! ion transmembrane transport GO:0034220 79 43 1,000 0,02158466 0,1341764 ! response to reactive oxygen species GO:0000302 75 44 1,000 0,02253539 0,13973085 ! striated muscle contraction GO:0006941 85 44 1,000 0,02253539 0,1393771 ! keratinocyte differentiation GO:0030216 81 45 1,000 0,02350316 0,14499549 ! biopolymer methylation GO:0043414 91 45 1,000 0,02350316 0,14463026 ! B cell differentiation GO:0030183 124 45 1,000 0,02350316 0,14426687 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 1,000 0,02350316 0,1439053 ! female gamete generation GO:0007292 71 45 1,000 0,02350316 0,14354554 ! developmental growth GO:0048589 88 45 1,000 0,02350316 0,14318757 ! maintenance of location in cell GO:0051651 101 45 1,000 0,02350316 0,14283138 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 1,000 0,02448776 0,14844567 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 1,000 0,02448776 0,14807823 ! regulation of gene-specific transcription GO:0032583 102 46 1,000 0,02448776 0,14771261 ! response to insulin stimulus GO:0032868 98 47 1,000 0,025489 0,15337348 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 0,02603154 0,15625317 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 0,02603154 0,1558702 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 0,02603154 0,1554891 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,02603154 0,15510986 ! positive regulation of helicase activity GO:0051096 12 5 0,000 0,02603154 0,15473246 ! neuron fate determination GO:0048664 7 5 0,000 0,02603154 0,1543569 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02603154 0,15398315 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 0,02603154 0,15361121 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 0,02603154 0,15324107 ! polyol transport GO:0015791 12 5 0,000 0,02603154 0,1528727 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,02603154 0,1525061 ! response to superoxide GO:0000303 10 5 0,000 0,02603154 0,15214125 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,02603154 0,15177814 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 0,02603154 0,15141677 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 0,02603154 0,15105711 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,02603154 0,15069915 ! female meiosis GO:0007143 10 5 0,000 0,02603154 0,15034289 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 0,02603154 0,14998831 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,02603154 0,14963539 ! hypothalamus development GO:0021854 9 5 0,000 0,02603154 0,14928414 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 0,02603154 0,14893453 ! cobalt ion transport GO:0006824 11 5 0,000 0,02603154 0,14858655 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 0,02603154 0,14824019 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 0,02603154 0,14789545 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,02603154 0,1475523 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,02603154 0,14721075 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 0,02603154 0,14687077 ! embryonic camera-type eye development GO:0031076 12 5 0,000 0,02603154 0,14653236 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,02603154 0,1461955 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02603154 0,14586019 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 0,02603154 0,14552641 ! transposition GO:0032196 9 5 0,000 0,02603154 0,14519416 ! negative chemotaxis GO:0050919 16 5 0,000 0,02603154 0,14486342 ! positive regulation of histone modification GO:0031058 6 5 0,000 0,02603154 0,14453419 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,02603154 0,14420644 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 0,02603154 0,14388019 ! behavioral response to pain GO:0048266 10 5 0,000 0,02603154 0,1435554 ! clathrin coat assembly GO:0048268 15 5 0,000 0,02603154 0,14323208 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02603154 0,14291021 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 0,02603154 0,14258978 ! micturition GO:0060073 9 5 0,000 0,02603154 0,14227079 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,02603154 0,14195322 ! copulation GO:0007620 9 5 0,000 0,02603154 0,14163707 ! glial cell fate commitment GO:0021781 14 5 0,000 0,02603154 0,14132232 ! protein maturation by protein folding GO:0022417 14 5 0,000 0,02603154 0,14100896 ! bioluminescence GO:0008218 9 5 0,000 0,02603154 0,140697 ! spermidine metabolic process GO:0008216 7 5 0,000 0,02603154 0,14038641 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,02603154 0,14007719 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,02603154 0,13976932 ! apoptotic cell clearance GO:0043277 23 5 0,000 0,02603154 0,13946281 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,02603154 0,13915764 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 0,02603154 0,1388538 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,02603154 0,13855129 ! grooming behavior GO:0007625 6 5 0,000 0,02603154 0,13825009 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 0,02603154 0,1379502 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,02603154 0,13765161 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 0,02603154 0,1373543 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02603154 0,13705828 ! response to protozoan GO:0001562 13 5 0,000 0,02603154 0,13676353 ! positive regulation of glycolysis GO:0045821 13 5 0,000 0,02603154 0,13647005 ! lymph vessel development GO:0001945 10 5 0,000 0,02603154 0,13617782 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 0,02603154 0,13588684 ! endochondral ossification GO:0001958 17 5 0,000 0,02603154 0,1355971 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,02603154 0,1353086 ! single strand break repair GO:0000012 8 5 0,000 0,02603154 0,13502132 ! parathyroid gland development GO:0060017 14 5 0,000 0,02603154 0,13473526 ! anagen GO:0042640 7 5 0,000 0,02603154 0,13445041 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,02603154 0,13416676 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,02603154 0,1338843 ! cytokine secretion GO:0050663 15 5 0,000 0,02603154 0,13360303 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 0,02603154 0,13332294 ! ceramide catabolic process GO:0046514 7 5 0,000 0,02603154 0,13304402 ! skeletal myofibril assembly GO:0014866 12 5 0,000 0,02603154 0,13276627 ! smooth muscle tissue development GO:0048745 32 5 0,000 0,02603154 0,13248967 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,02603154 0,13221422 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,02603154 0,13193992 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,02603154 0,13166675 ! cardiac muscle fiber development GO:0048739 12 5 0,000 0,02603154 0,13139472 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,02603154 0,1311238 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,02603154 0,130854 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 0,02603154 0,1305853 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,02603154 0,13031771 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 0,02603154 0,13005121 ! glycine biosynthetic process GO:0006545 7 5 0,000 0,02603154 0,1297858 ! microvillus organization GO:0032528 8 5 0,000 0,02603154 0,12952147 GO:0030033|microvillus assembly, ! endoplasmic reticulum organization GO:0007029 12 5 0,000 0,02603154 0,12925822 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 0,02603154 0,12899603 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 0,02603154 0,1287349 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 0,02603154 0,12847483 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 0,02603154 0,12821581 ! polyol biosynthetic process GO:0046173 6 5 0,000 0,02603154 0,12795783 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 0,02603154 0,12770089 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 0,02603154 0,12744497 ! muscle cell migration GO:0014812 8 5 0,000 0,02603154 0,12719008 ! mitochondrial fission GO:0000266 8 5 0,000 0,02603154 0,12693621 ! sister chromatid cohesion GO:0007062 15 5 0,000 0,02603154 0,12668335 ! response to tumor necrosis factor GO:0034612 10 5 0,000 0,02603154 0,1264315 ! mRNA transcription GO:0009299 10 5 0,000 0,02603154 0,12618064 ! nerve growth factor processing GO:0032455 9 5 0,000 0,02603154 0,12593078 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 0,02603154 0,1256819 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 0,02603154 0,12543401 ! anaerobic glycolysis GO:0019642 6 5 0,000 0,02603154 0,12518709 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,02603154 0,12494114 ! monocyte activation GO:0042117 10 5 0,000 0,02603154 0,12469616 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,02603154 0,12445214 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,02603154 0,12420907 ! response to food GO:0032094 6 5 0,000 0,02603154 0,12396694 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,02603154 0,12372576 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,02603154 0,12348552 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 0,02603154 0,12324621 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02603154 0,12300782 ! regulation of phospholipase A2 activity GO:0032429 15 5 0,000 0,02603154 0,12277035 ! forebrain neuron development GO:0021884 13 5 0,000 0,02603154 0,1225338 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,02603154 0,12229816 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 0,02603154 0,12206342 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 0,02603154 0,12182958 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,02603154 0,12159664 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02603154 0,12136458 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 0,02603154 0,12113341 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,02603154 0,12090312 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 0,02603154 0,1206737 ! lipid glycosylation GO:0030259 7 5 0,000 0,02603154 0,12044516 ! nucleobase transport GO:0015851 6 5 0,000 0,02603154 0,12021747 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02603154 0,11999065 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 0,02603154 0,11976467 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 0,02603154 0,11953955 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 0,02603154 0,11931528 ! basic amino acid transport GO:0015802 12 5 0,000 0,02603154 0,11909184 ! cellular glucose homeostasis GO:0001678 6 5 0,000 0,02603154 0,11886924 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 0,02603154 0,11864747 ! actin nucleation GO:0045010 11 5 0,000 0,02603154 0,11842652 ! depurination GO:0045007 5 5 0,000 0,02603154 0,1182064 ! depyrimidination GO:0045008 10 5 0,000 0,02603154 0,11798709 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,02603154 0,1177686 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02603154 0,11755091 ! G2/M transition checkpoint GO:0031576 8 5 0,000 0,02603154 0,11733403 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,02603154 0,11711794 ! zinc ion homeostasis GO:0055069 9 5 0,000 0,02603154 0,11690265 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 10 5 0,000 0,02603154 0,11668815 ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 0,02603154 0,11647444 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02603154 0,1162615 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,02603154 0,11604935 ! activated T cell proliferation GO:0050798 16 5 0,000 0,02603154 0,11583796 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,02603154 0,11562735 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 0,02603154 0,1154175 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,02603154 0,11520841 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02603154 0,11500008 ! gamma-delta T cell activation GO:0046629 6 5 0,000 0,02603154 0,11479249 ! response to arsenic GO:0046685 11 5 0,000 0,02603154 0,11458566 ! mast cell degranulation GO:0043303 7 5 0,000 0,02603154 0,11437957 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 0,02603154 0,11417422 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 0,02603154 0,11396961 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 0,02603154 0,11376573 ! response to mercury ion GO:0046689 8 5 0,000 0,02603154 0,11356258 ! response to cadmium ion GO:0046686 7 5 0,000 0,02603154 0,11336015 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 0,02603154 0,11315844 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 0,02603154 0,11295745 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 0,02603154 0,11275717 ! bile acid biosynthetic process GO:0006699 7 5 0,000 0,02603154 0,1125576 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 0,02603154 0,11235873 ! ganglioside catabolic process GO:0006689 12 5 0,000 0,02603154 0,11216057 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,02603154 0,1119631 ! decidualization GO:0046697 11 5 0,000 0,02603154 0,11176633 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 0,02603154 0,11157025 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 0,02603154 0,11137485 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 0,02603154 0,11118014 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 0,02603154 0,11098611 ! embryonic cleavage GO:0040016 6 5 0,000 0,02603154 0,11079276 ! peroxisome fission GO:0016559 5 5 0,000 0,02603154 0,11060007 ! histone demethylation GO:0016577 13 5 0,000 0,02603154 0,11040806 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 0,02603154 0,11021671 ! mitotic recombination GO:0006312 9 5 0,000 0,02603154 0,11002602 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 0,02603154 0,109836 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,02603154 0,10964662 ! metaphase plate congression GO:0051310 7 5 0,000 0,02603154 0,1094579 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02603154 0,10926983 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,02603154 0,10908241 ! enteric nervous system development GO:0048484 8 5 0,000 0,02603154 0,10889562 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 0,02603154 0,10870947 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 0,02603154 0,10852396 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 0,02603154 0,10833908 ! muscle cell proliferation GO:0033002 12 5 0,000 0,02603154 0,10815483 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,02603154 0,10797121 ! B cell homeostasis GO:0001782 13 5 0,000 0,02603154 0,10778821 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 0,02603154 0,10760582 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,02603154 0,10742406 ! metaphase GO:0051323 11 5 0,000 0,02603154 0,1072429 ! melatonin biosynthetic process GO:0030187 7 5 0,000 0,02603154 0,10706236 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 0,02603154 0,10688242 ! cellular response to nutrient GO:0031670 8 5 0,000 0,02603154 0,10670309 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,02603154 0,10652436 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 0,02603154 0,10634622 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 0,02603154 0,10616868 ! regulation of hair follicle development GO:0051797 10 5 0,000 0,02603154 0,10599174 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 0,02603154 0,10581538 ! response to redox state GO:0051775 6 5 0,000 0,02603154 0,1056396 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 0,02603154 0,10546441 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 0,02603154 0,1052898 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,02603154 0,10511577 ! brown fat cell differentiation GO:0050873 7 5 0,000 0,02603154 0,10494231 ! regulation of telomerase activity GO:0051972 7 5 0,000 0,02603154 0,10476943 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02603154 0,10459711 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 0,02603154 0,10442536 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02603154 0,10425417 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 0,02603154 0,10408354 ! striatum development GO:0021756 14 5 0,000 0,02603154 0,10391347 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,02603154 0,10374395 ! glial cell migration GO:0008347 10 5 0,000 0,02603154 0,10357499 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 0,02603154 0,10340657 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,02603154 0,1032387 ! T cell activation during immune response GO:0002286 9 5 0,000 0,02603154 0,10307138 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,02603154 0,1029046 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,02603154 0,10273836 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 0,02603154 0,10257265 ! neuroprotection GO:0043526 8 5 0,000 0,02603154 0,10240748 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,02603154 0,10224283 ! regulation of sensory perception GO:0051931 8 5 0,000 0,02603154 0,10207872 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,02603154 0,10191513 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,02603154 0,10175207 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 0,02603154 0,10158952 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 0,02603154 0,1014275 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,02603154 0,10126599 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 0,02603154 0,101105 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,02603154 0,10094451 ! protein insertion into membrane GO:0051205 17 5 0,000 0,02603154 0,10078454 ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 0,02603154 0,10062507 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,02603154 0,1004661 ! spindle assembly GO:0051225 6 5 0,000 0,02603154 0,10030764 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,02603154 0,10014967 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,02603154 0,0999922 ! protein palmitoylation GO:0018345 12 5 0,000 0,02603154 0,09983523 ! drug metabolic process GO:0017144 7 5 0,000 0,02603154 0,09967875 ! stem cell division GO:0017145 11 5 0,000 0,02603154 0,09952276 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,02603154 0,09936725 ! organ regeneration GO:0031100 7 5 0,000 0,02603154 0,09921223 ! carnitine metabolic process GO:0009437 8 5 0,000 0,02603154 0,0990577 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,02603154 0,09890364 ! positive regulation of cell cycle GO:0045787 96 48 1,000 0,02650668 0,10055251 ! mitochondrial transport GO:0006839 94 48 1,000 0,02650668 0,10039661 ! regulation of JAK-STAT cascade GO:0046425 76 48 1,000 0,02650668 0,1002412 ! cellular component disassembly GO:0022411 89 48 1,000 0,02650668 0,10008627 ! regulation of adaptive immune response GO:0002819 92 48 1,000 0,02650668 0,09993181 ! methylation GO:0032259 97 48 1,000 0,02650668 0,09977783 ! response to calcium ion GO:0051592 94 49 1,000 0,02754059 0,10351024 ! regulation of action potential GO:0001508 102 50 1,000 0,02859054 0,10729137 ! regulation of gene expression, epigenetic GO:0040029 116 50 1,000 0,02859054 0,10712681 ! epidermal cell differentiation GO:0009913 87 50 1,000 0,02859054 0,10696276 ! viral infectious cycle GO:0019058 104 51 1,000 0,02965633 0,11078045 ! response to temperature stimulus GO:0009266 84 51 1,000 0,02965633 0,11061132 ! DNA-dependent DNA replication GO:0006261 82 52 1,000 0,03073777 0,11447009 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,03115639 0,11585244 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,03115639 0,11567638 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 0,03115639 0,11550084 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 0,03115639 0,11532584 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,03115639 0,11515137 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 0,03115639 0,11497742 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 0,03115639 0,114804 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,03115639 0,11463111 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 0,03115639 0,11445873 ! response to oxygen radical GO:0000305 11 6 0,000 0,03115639 0,11428687 ! positive regulation of axon extension GO:0045773 13 6 0,000 0,03115639 0,11411552 ! myoblast cell fate commitment GO:0048625 18 6 0,000 0,03115639 0,11394469 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 0,03115639 0,11377437 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 0,03115639 0,11360456 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,03115639 0,11343525 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,03115639 0,11326645 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 0,03115639 0,11309815 ! forebrain regionalization GO:0021871 9 6 0,000 0,03115639 0,11293035 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,03115639 0,11276304 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,03115639 0,11259623 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 0,03115639 0,11242992 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,03115639 0,11226409 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 0,03115639 0,11209876 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,03115639 0,1119339 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 0,03115639 0,11176954 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 0,03115639 0,11160565 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,03115639 0,11144225 ! malate metabolic process GO:0006108 13 6 0,000 0,03115639 0,11127932 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 0,03115639 0,11111687 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 0,03115639 0,11095489 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 0,03115639 0,11079338 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 0,03115639 0,11063235 ! protein refolding GO:0042026 15 6 0,000 0,03115639 0,11047178 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,03115639 0,11031167 ! opsonization GO:0008228 8 6 0,000 0,03115639 0,11015203 ! mating behavior GO:0007617 7 6 0,000 0,03115639 0,10999285 ! erythrocyte maturation GO:0043249 8 6 0,000 0,03115639 0,10983413 ! embryonic hemopoiesis GO:0035162 16 6 0,000 0,03115639 0,10967587 ! protein amino acid dealkylation GO:0008214 15 6 0,000 0,03115639 0,10951806 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 0,03115639 0,10936071 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 0,03115639 0,10920381 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,03115639 0,10904736 ! response to interferon-gamma GO:0034341 16 6 0,000 0,03115639 0,10889135 ! toxin metabolic process GO:0009404 11 6 0,000 0,03115639 0,10873579 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,03115639 0,10858068 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 0,03115639 0,108426 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 0,03115639 0,10827177 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 0,03115639 0,10811798 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 13 6 0,000 0,03115639 0,10796462 ! cGMP-mediated signaling GO:0019934 14 6 0,000 0,03115639 0,10781169 ! dorsal spinal cord development GO:0021516 10 6 0,000 0,03115639 0,1076592 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 0,03115639 0,10750714 ! sphingoid catabolic process GO:0046521 8 6 0,000 0,03115639 0,10735551 ! protein lipoylation GO:0009249 10 6 0,000 0,03115639 0,1072043 ! transepithelial chloride transport GO:0030321 12 6 0,000 0,03115639 0,10705352 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 0,03115639 0,10690317 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,03115639 0,10675323 ! glutamate catabolic process GO:0006538 12 6 0,000 0,03115639 0,10660372 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 0,03115639 0,10645462 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,03115639 0,10630594 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 0,03115639 0,10615768 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,03115639 0,10600983 ! hyperosmotic response GO:0006972 10 6 0,000 0,03115639 0,10586238 ! L-serine biosynthetic process GO:0006564 7 6 0,000 0,03115639 0,10571535 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 0,03115639 0,10556873 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 0,03115639 0,10542251 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,03115639 0,1052767 ! urea metabolic process GO:0019627 7 6 0,000 0,03115639 0,10513129 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,03115639 0,10498628 ! neutrophil activation GO:0042119 7 6 0,000 0,03115639 0,10484167 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,03115639 0,10469746 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 0,03115639 0,10455365 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,03115639 0,10441023 ! paraxial mesoderm development GO:0048339 16 6 0,000 0,03115639 0,1042672 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 0,03115639 0,10412456 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,03115639 0,10398232 ! neuron apoptosis GO:0051402 15 6 0,000 0,03115639 0,10384046 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,03115639 0,10369898 ! T cell mediated immunity GO:0002456 17 6 0,000 0,03115639 0,1035579 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,03115639 0,10341719 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 0,03115639 0,10327687 ! carnitine transport GO:0015879 10 6 0,000 0,03115639 0,10313693 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,03115639 0,10299737 ! positive regulation of exocytosis GO:0045921 11 6 0,000 0,03115639 0,10285818 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 0,03115639 0,10271937 ! early endosome to late endosome transport GO:0045022 16 6 0,000 0,03115639 0,10258094 ! 5S class rRNA transcription GO:0042791 13 6 0,000 0,03115639 0,10244287 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! neuronal ion channel clustering GO:0045161 15 6 0,000 0,03115639 0,10230518 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 0,03115639 0,10216786 ! sodium ion homeostasis GO:0055078 12 6 0,000 0,03115639 0,1020309 ! establishment of spindle localization GO:0051293 16 6 0,000 0,03115639 0,10189432 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 0,03115639 0,10175809 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,03115639 0,10162224 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 0,000 0,03115639 0,10148674 ! astrocyte development GO:0014002 16 6 0,000 0,03115639 0,1013516 ! protein targeting to lysosome GO:0006622 12 6 0,000 0,03115639 0,10121683 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,03115639 0,10108241 ! interaction with symbiont GO:0051702 14 6 0,000 0,03115639 0,10094835 ! regulation of dendrite development GO:0050773 16 6 0,000 0,03115639 0,10081464 ! peptidyl-arginine modification GO:0018195 13 6 0,000 0,03115639 0,10068129 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 0,03115639 0,10054829 ! response to copper ion GO:0046688 10 6 0,000 0,03115639 0,10041564 ! response to exogenous dsRNA GO:0043330 13 6 0,000 0,03115639 0,10028334 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 0,03115639 0,10015139 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,03115639 0,10001978 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 0,03115639 0,09988852 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,03115639 0,09975761 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 0,03115639 0,09962704 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,03115639 0,0994968 ! nucleoside catabolic process GO:0009164 10 6 0,000 0,03115639 0,09936691 ! hair follicle maturation GO:0048820 8 6 0,000 0,03115639 0,09923736 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,03115639 0,09910814 ! Schwann cell development GO:0014044 15 6 0,000 0,03115639 0,09897926 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 0,03115639 0,09885072 ! response to pheromone GO:0019236 6 6 0,000 0,03115639 0,09872251 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 0,03115639 0,09859463 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 0,03115639 0,09846708 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 0,03115639 0,09833986 ! base conversion or substitution editing GO:0016553 6 6 0,000 0,03115639 0,09821297 ! subpallium development GO:0021544 15 6 0,000 0,03115639 0,09808641 ! neural tube patterning GO:0021532 8 6 0,000 0,03115639 0,09796017 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 0,03115639 0,09783426 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 0,03115639 0,09770867 ! maintenance of organ identity GO:0048496 9 6 0,000 0,03115639 0,0975834 ! G2 phase GO:0051319 16 6 0,000 0,03115639 0,09745846 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 0,03115639 0,09733383 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 0,03115639 0,09720952 ! oxygen homeostasis GO:0032364 10 6 0,000 0,03115639 0,09708553 ! establishment of planar polarity GO:0001736 7 6 0,000 0,03115639 0,09696185 ! regulation of mast cell activation GO:0033003 13 6 0,000 0,03115639 0,09683849 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,03115639 0,09671544 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 0,03115639 0,09659271 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,03115639 0,09647028 ! receptor internalization GO:0031623 11 6 0,000 0,03115639 0,09634817 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 0,03115639 0,09622637 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 0,03115639 0,09610487 ! neutrophil homeostasis GO:0001780 11 6 0,000 0,03115639 0,09598368 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,03115639 0,09586279 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 0,03115639 0,09574221 ! protein deubiquitination GO:0016579 16 6 0,000 0,03115639 0,09562193 ! protein destabilization GO:0031648 9 6 0,000 0,03115639 0,09550195 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 0,03115639 0,09538227 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,03115639 0,0952629 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 0,03115639 0,09514382 ! regulation of viral transcription GO:0046782 11 6 0,000 0,03115639 0,09502504 ! progesterone metabolic process GO:0042448 12 6 0,000 0,03115639 0,09490655 ! negative regulation of axon extension GO:0030517 24 6 0,000 0,03115639 0,09478836 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 0,03115639 0,09467047 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 0,03115639 0,09455286 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,03115639 0,09443555 ! determination of adult lifespan GO:0008340 17 6 0,000 0,03115639 0,09431853 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 0,03115639 0,0942018 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 0,03115639 0,09408536 ! catecholamine transport GO:0051937 9 6 0,000 0,03115639 0,0939692 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 0,03115639 0,09385334 ! sensory cilium assembly GO:0035058 10 6 0,000 0,03115639 0,09373775 ! organ or tissue specific immune response GO:0002251 8 6 0,000 0,03115639 0,09362245 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 0,03115639 0,09350744 ! maternal placenta development GO:0001893 12 6 0,000 0,03115639 0,09339271 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 0,03115639 0,09327825 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,03115639 0,09316408 ! negative regulation of B cell activation GO:0050869 14 6 0,000 0,03115639 0,09305019 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 0,03115639 0,09293657 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 0,03115639 0,09282324 ! positive regulation of coagulation GO:0050820 13 6 0,000 0,03115639 0,09271018 ! cellular anion homeostasis GO:0030002 11 6 0,000 0,03115639 0,09259739 GO:0055081|anion homeostasis, ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 1,000 0,03183467 0,0944983 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 1,000 0,03183467 0,09438362 ! vesicle organization GO:0016050 127 53 1,000 0,03183467 0,09426921 ! regulation of neuron apoptosis GO:0043523 117 53 1,000 0,03183467 0,09415509 ! regulation of angiogenesis GO:0045765 125 54 1,000 0,03294684 0,09732663 ! regulation of translational initiation GO:0006446 87 54 1,000 0,03294684 0,09720909 ! membrane fusion GO:0006944 122 54 1,000 0,03294684 0,09709182 ! regulation of cell shape GO:0008360 142 54 1,000 0,03294684 0,09697485 ! regulation of multicellular organism growth GO:0040014 90 55 1,000 0,03407408 0,10017206 ! cell maturation GO:0048469 107 55 1,000 0,03407408 0,10005166 ! skeletal muscle fiber development GO:0048741 130 56 1,000 0,03521621 0,10328116 ! tRNA transcription GO:0009304 17 7 0,000 0,03625442 0,10619849 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 0,03625442 0,10607131 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 0,03625442 0,10594443 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,03625442 0,10581785 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,03625442 0,10569157 ! sleep GO:0030431 16 7 0,000 0,03625442 0,1055656 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,03625442 0,10543993 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 0,03625442 0,10531455 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,03625442 0,10518948 ! prostate gland development GO:0030850 14 7 0,000 0,03625442 0,1050647 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,03625442 0,10494021 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,03625442 0,10481602 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,03625442 0,10469213 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,03625442 0,10456852 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,03625442 0,10444521 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,03625442 0,10432219 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,03625442 0,10419946 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,03625442 0,10407701 ! SMAD protein complex assembly GO:0007183 13 7 0,000 0,03625442 0,10395486 ! glycolipid transport GO:0046836 11 7 0,000 0,03625442 0,10383299 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,03625442 0,1037114 GO:0051923|sulfation, ! neuron adhesion GO:0007158 14 7 0,000 0,03625442 0,1035901 ! N-terminal protein amino acid acetylation GO:0006474 14 7 0,000 0,03625442 0,10346909 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,03625442 0,10334835 ! establishment of tissue polarity GO:0007164 8 7 0,000 0,03625442 0,1032279 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 0,03625442 0,10310773 ! mRNA stabilization GO:0048255 18 7 0,000 0,03625442 0,10298784 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 0,03625442 0,10286822 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 0,03625442 0,10274889 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 0,03625442 0,10262983 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 0,03625442 0,10251104 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,03625442 0,10239253 ! lipoprotein transport GO:0042953 14 7 0,000 0,03625442 0,1022743 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,03625442 0,10215633 ! rhythmic behavior GO:0007622 17 7 0,000 0,03625442 0,10203864 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 0,03625442 0,10192122 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 0,03625442 0,10180407 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,03625442 0,10168719 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 0,03625442 0,10157057 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,03625442 0,10145423 ! regulation of odontogenesis GO:0042481 14 7 0,000 0,03625442 0,10133815 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,03625442 0,10122233 ! mechanosensory behavior GO:0007638 16 7 0,000 0,03625442 0,10110678 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 0,03625442 0,10099149 ! positive regulation of heart rate GO:0010460 11 7 0,000 0,03625442 0,10087647 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,03625442 0,10076171 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,03625442 0,1006472 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,03625442 0,10053296 ! spinal cord patterning GO:0021511 14 7 0,000 0,03625442 0,10041898 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 0,03625442 0,10030525 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,03625442 0,10019179 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,03625442 0,10007858 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 0,03625442 0,09996562 ! adrenal gland development GO:0030325 17 7 0,000 0,03625442 0,09985292 ! cysteine metabolic process GO:0006534 13 7 0,000 0,03625442 0,09974047 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 0,03625442 0,09962828 ! ovulation GO:0030728 10 7 0,000 0,03625442 0,09951634 ! adenohypophysis development GO:0021984 11 7 0,000 0,03625442 0,09940465 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 0,03625442 0,09929321 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 0,03625442 0,09918202 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 0,03625442 0,09907107 ! microtubule nucleation GO:0007020 21 7 0,000 0,03625442 0,09896038 ! proline biosynthetic process GO:0006561 10 7 0,000 0,03625442 0,09884993 ! tryptophan metabolic process GO:0006568 11 7 0,000 0,03625442 0,09873973 ! thyroid hormone generation GO:0006590 13 7 0,000 0,03625442 0,09862978 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 0,03625442 0,09852007 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,03625442 0,0984106 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,03625442 0,09830138 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,03625442 0,09819239 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,03625442 0,09808365 ! galactose metabolic process GO:0006012 13 7 0,000 0,03625442 0,09797515 ! response to dietary excess GO:0002021 8 7 0,000 0,03625442 0,09786689 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,03625442 0,09775887 ! intracellular pH reduction GO:0051452 13 7 0,000 0,03625442 0,09765109 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,03625442 0,09754355 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 0,03625442 0,09743624 ! organ growth GO:0035265 15 7 0,000 0,03625442 0,09732916 ! nucleoside transport GO:0015858 11 7 0,000 0,03625442 0,09722233 ! nucleoside salvage GO:0043174 11 7 0,000 0,03625442 0,09711572 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 0,03625442 0,09700935 ! male sex determination GO:0030238 15 7 0,000 0,03625442 0,09690322 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,03625442 0,09679731 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 0,03625442 0,09669164 ! parturition GO:0007567 16 7 0,000 0,03625442 0,09658619 ! rRNA modification GO:0000154 14 7 0,000 0,03625442 0,09648098 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,03625442 0,096376 ! spindle checkpoint GO:0031577 16 7 0,000 0,03625442 0,09627124 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 0,03625442 0,09616671 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,03625442 0,09606241 ! monocyte differentiation GO:0030224 16 7 0,000 0,03625442 0,09595833 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,03625442 0,09585448 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,03625442 0,09575085 GO:0046676|negative regulation of insulin secretion, ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,03625442 0,09564745 ! fibrinolysis GO:0042730 11 7 0,000 0,03625442 0,09554427 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 0,000 0,03625442 0,09544131 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,03625442 0,09533858 ! eating behavior GO:0042755 8 7 0,000 0,03625442 0,09523606 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,03625442 0,09513377 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 0,03625442 0,09503169 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 0,03625442 0,09492984 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,03625442 0,0948282 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 0,03625442 0,09472678 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,03625442 0,09462558 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 0,03625442 0,09452459 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 0,03625442 0,09442382 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 0,03625442 0,09432326 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 0,03625442 0,09422291 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,03625442 0,09412278 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 0,03625442 0,09402287 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,03625442 0,09392316 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,03625442 0,09382366 ! histone ubiquitination GO:0016574 9 7 0,000 0,03625442 0,09372438 ! regulation of meiosis GO:0040020 12 7 0,000 0,03625442 0,09362531 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 0,03625442 0,09352644 ! regulation of lipid transport GO:0032368 14 7 0,000 0,03625442 0,09342778 ! membrane to membrane docking GO:0022614 14 7 0,000 0,03625442 0,09332934 ! transcription termination GO:0006353 14 7 0,000 0,03625442 0,09323109 ! anaphase GO:0051322 18 7 0,000 0,03625442 0,09313306 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 0,03625442 0,09303523 ! axonal fasciculation GO:0007413 19 7 0,000 0,03625442 0,09293761 ! negative regulation of nuclear division GO:0051784 15 7 0,000 0,03625442 0,09284019 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 0,03625442 0,09274297 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,03625442 0,09264596 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 0,03625442 0,09254915 ! diuresis GO:0030146 12 7 0,000 0,03625442 0,09245255 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,03625442 0,09235614 ! thiamin metabolic process GO:0006772 7 7 0,000 0,03625442 0,09225994 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,03625442 0,09216393 ! antibiotic transport GO:0042891 9 7 0,000 0,03625442 0,09206813 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,03625442 0,09197252 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 0,03625442 0,09187712 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 0,03625442 0,09178191 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 0,03625442 0,09168689 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,03625442 0,09159208 ! melanin biosynthetic process GO:0042438 10 7 0,000 0,03625442 0,09149746 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 0,03625442 0,09140303 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,03625442 0,0913088 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,03625442 0,09121477 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 0,03625442 0,09112093 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,03625442 0,09102728 ! endosome to lysosome transport GO:0008333 12 7 0,000 0,03625442 0,09093382 ! protein modification by small protein removal GO:0070646 19 7 0,000 0,03625442 0,09084055 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 0,03625442 0,09074748 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,03625442 0,0906546 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 0,03625442 0,0905619 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,03625442 0,0904694 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,03625442 0,09037708 ! muscle adaptation GO:0043500 13 7 0,000 0,03625442 0,09028495 ! embryonic heart tube development GO:0035050 14 7 0,000 0,03625442 0,09019301 ! retina homeostasis GO:0001895 12 7 0,000 0,03625442 0,09010126 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 0,03625442 0,09000969 ! protein amino acid prenylation GO:0018346 19 7 0,000 0,03625442 0,08991831 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 0,03625442 0,08982712 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 0,03625442 0,08973611 ! muscle fiber development GO:0048747 131 57 1,000 0,03637305 0,08993863 ! regulation of intracellular transport GO:0032386 108 57 1,000 0,03637305 0,08984769 ! positive regulation of cell migration GO:0030335 137 58 1,000 0,03754441 0,09264746 ! maintenance of location GO:0051235 124 58 1,000 0,03754441 0,09255397 ! nuclear export GO:0051168 110 59 1,000 0,0387301 0,09538068 ! DNA catabolic process GO:0006308 94 60 1,000 0,03992995 0,09823652 ! heterocycle catabolic process GO:0046700 100 60 1,000 0,03992995 0,09813769 ! proton transport GO:0015992 117 61 1,000 0,04114377 0,10101933 ! negative regulation of response to stimulus GO:0048585 106 61 1,000 0,04114377 0,1009179 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,04132576 0,10126263 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,04132576 0,10116116 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 0,000 0,04132576 0,1010599 ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 0,04132576 0,10095884 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 0,04132576 0,10085798 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,04132576 0,10075732 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,04132576 0,10065687 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,04132576 0,10055661 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,04132576 0,10045656 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,04132576 0,1003567 ! meiotic prophase I GO:0007128 14 8 0,000 0,04132576 0,10025704 ! response to zinc ion GO:0010043 12 8 0,000 0,04132576 0,10015758 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,04132576 0,10005831 ! oligopeptide transport GO:0006857 16 8 0,000 0,04132576 0,09995925 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,04132576 0,09986037 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,04132576 0,0997617 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,04132576 0,09966322 ! signal peptide processing GO:0006465 12 8 0,000 0,04132576 0,09956493 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,04132576 0,09946684 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,04132576 0,09936894 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,04132576 0,09927123 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,04132576 0,09917371 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,04132576 0,09907639 ! estrogen metabolic process GO:0008210 17 8 0,000 0,04132576 0,09897925 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,04132576 0,09888231 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,04132576 0,09878556 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,04132576 0,09868899 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,04132576 0,09859262 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,04132576 0,09849643 ! reflex GO:0060004 17 8 0,000 0,04132576 0,09840043 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,04132576 0,09830461 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,04132576 0,09820899 ! hemoglobin metabolic process GO:0020027 14 8 0,000 0,04132576 0,09811355 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,04132576 0,09801829 ! pigment granule organization GO:0048753 17 8 0,000 0,04132576 0,09792322 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,04132576 0,09782833 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,04132576 0,09773363 ! astrocyte differentiation GO:0048708 19 8 0,000 0,04132576 0,09763911 ! histidine catabolic process GO:0006548 10 8 0,000 0,04132576 0,09754477 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,04132576 0,09745062 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,04132576 0,09735664 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,04132576 0,09726285 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,04132576 0,09716924 ! regulation of pigmentation during development GO:0048070 25 8 0,000 0,04132576 0,09707581 ! melanin metabolic process GO:0006582 17 8 0,000 0,04132576 0,09698255 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,04132576 0,09688948 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,04132576 0,09679658 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,04132576 0,09670387 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,04132576 0,09661133 ! macrophage activation GO:0042116 13 8 0,000 0,04132576 0,09651897 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,04132576 0,09642678 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,04132576 0,09633477 ! positive regulation of insulin secretion GO:0032024 17 8 0,000 0,04132576 0,09624293 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,04132576 0,09615127 ! purine salvage GO:0043101 12 8 0,000 0,04132576 0,09605979 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,04132576 0,09596848 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,04132576 0,09587734 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,04132576 0,09578637 ! osteoblast development GO:0002076 17 8 0,000 0,04132576 0,09569558 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,04132576 0,09560496 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,04132576 0,09551451 ! Schwann cell differentiation GO:0014037 21 8 0,000 0,04132576 0,09542423 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,04132576 0,09533412 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,04132576 0,09524419 ! response to UV-B GO:0010224 17 8 0,000 0,04132576 0,09515442 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,04132576 0,09506482 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,04132576 0,09497539 ! intermediate filament organization GO:0045109 12 8 0,000 0,04132576 0,09488613 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,04132576 0,09479703 ! cellular extravasation GO:0045123 13 8 0,000 0,04132576 0,0947081 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,04132576 0,09461934 ! response to antibiotic GO:0046677 11 8 0,000 0,04132576 0,09453075 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,04132576 0,09444232 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,04132576 0,09435405 ! DNA topological change GO:0006265 12 8 0,000 0,04132576 0,09426596 ! response to tropane GO:0014073 15 8 0,000 0,04132576 0,09417802 GO:0042220|response to cocaine, ! melanosome transport GO:0032402 13 8 0,000 0,04132576 0,09409025 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,04132576 0,09400264 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,04132576 0,0939152 ! mast cell activation GO:0045576 14 8 0,000 0,04132576 0,09382792 ! multicellular organismal aging GO:0010259 20 8 0,000 0,04132576 0,0937408 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 0,04132576 0,09365384 ! gas homeostasis GO:0033483 14 8 0,000 0,04132576 0,09356704 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,04132576 0,09348041 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,04132576 0,09339393 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,04132576 0,09330761 ! nucleosome disassembly GO:0006337 14 8 0,000 0,04132576 0,09322146 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,04132576 0,09313546 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 0,04132576 0,09304962 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,04132576 0,09296394 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,04132576 0,09287842 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,04132576 0,09279305 ! intracellular lipid transport GO:0032365 16 8 0,000 0,04132576 0,09270784 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,04132576 0,09262279 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of respiratory burst GO:0060263 12 8 0,000 0,04132576 0,09253789 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,04132576 0,09245315 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 0,04132576 0,09236856 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,04132576 0,09228413 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 0,04132576 0,09219985 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,04132576 0,09211573 ! hormone catabolic process GO:0042447 17 8 0,000 0,04132576 0,09203176 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,04132576 0,09194794 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,04132576 0,09186427 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,04132576 0,09178076 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,04132576 0,0916974 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,04132576 0,09161419 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,04132576 0,09153113 ! adult feeding behavior GO:0008343 10 8 0,000 0,04132576 0,09144822 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,04132576 0,09136546 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,04132576 0,09128286 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,04132576 0,0912004 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,04132576 0,09111808 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,04132576 0,09103592 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,04132576 0,09095391 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,04132576 0,09087204 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,04132576 0,09079032 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,04132576 0,09070875 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,04132576 0,09062732 GO:0006043|glucosamine catabolic process, ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,04132576 0,09054604 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,04132576 0,09046491 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,04132576 0,09038392 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 0,04132576 0,09030308 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 0,04132576 0,09022238 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,04132576 0,09014182 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,04132576 0,09006141 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 0,04132576 0,08998114 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 0,04132576 0,08990101 ! viral reproductive process GO:0022415 132 62 1,000 0,04237139 0,09209368 ! nucleoside metabolic process GO:0009116 91 62 1,000 0,04237139 0,09201182 ! skeletal system morphogenesis GO:0048705 118 63 1,000 0,04361263 0,09462313 ! hydrogen transport GO:0006818 121 64 1,000 0,04486731 0,09725895 ! protein amino acid autophosphorylation GO:0046777 157 64 1,000 0,04486731 0,09717272 ! response to peptide hormone stimulus GO:0043434 129 64 1,000 0,04486731 0,09708665 ! positive regulation of cell motion GO:0051272 157 65 1,000 0,04613526 0,09974198 ! axon extension GO:0048675 16 9 0,000 0,04637056 0,10016206 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,04637056 0,10007358 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,04637056 0,09998525 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 0,04637056 0,09989708 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,04637056 0,09980907 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,04637056 0,09972121 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,04637056 0,0996335 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,04637056 0,09954595 ! reproductive behavior GO:0019098 22 9 0,000 0,04637056 0,09945855 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,04637056 0,09937131 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 0,04637056 0,09928421 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 0,04637056 0,09919728 ! UTP metabolic process GO:0046051 10 9 0,000 0,04637056 0,09911049 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,04637056 0,09902385 ! induction of positive chemotaxis GO:0050930 17 9 0,000 0,04637056 0,09893737 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,04637056 0,09885104 ! artery development GO:0060840 25 9 0,000 0,04637056 0,09876486 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,04637056 0,09867882 ! regulation of glycolysis GO:0006110 20 9 0,000 0,04637056 0,09859294 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,04637056 0,09850721 ! equilibrioception GO:0050957 20 9 0,000 0,04637056 0,09842162 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,04637056 0,09833619 ! chemosensory behavior GO:0007635 21 9 0,000 0,04637056 0,0982509 ! microtubule bundle formation GO:0001578 22 9 0,000 0,04637056 0,09816576 ! leukocyte degranulation GO:0043299 16 9 0,000 0,04637056 0,09808077 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,04637056 0,09799592 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,04637056 0,09791123 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,04637056 0,09782667 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,04637056 0,09774227 ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,04637056 0,09765801 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,04637056 0,09757389 ! protein targeting to ER GO:0045047 25 9 0,000 0,04637056 0,09748992 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,04637056 0,0974061 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 0,04637056 0,09732241 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,04637056 0,09723887 ! glycine catabolic process GO:0006546 15 9 0,000 0,04637056 0,09715548 ! endosome organization GO:0007032 20 9 0,000 0,04637056 0,09707223 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,04637056 0,09698912 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,04637056 0,09690615 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,04637056 0,09682332 ! mannose metabolic process GO:0006013 13 9 0,000 0,04637056 0,09674064 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,04637056 0,0966581 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,04637056 0,09657569 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,04637056 0,09649343 ! receptor clustering GO:0043113 20 9 0,000 0,04637056 0,09641131 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,04637056 0,09632933 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,04637056 0,09624748 ! retinol metabolic process GO:0042572 20 9 0,000 0,04637056 0,09616578 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,04637056 0,09608421 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,04637056 0,09600279 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,04637056 0,0959215 ! macrophage differentiation GO:0030225 15 9 0,000 0,04637056 0,09584035 ! oligodendrocyte development GO:0014003 11 9 0,000 0,04637056 0,09575933 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 0,04637056 0,09567845 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,04637056 0,09559771 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,04637056 0,09551711 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,04637056 0,09543664 ! response to amine stimulus GO:0014075 13 9 0,000 0,04637056 0,0953563 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,04637056 0,09527611 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,04637056 0,09519604 ! erythrocyte development GO:0048821 17 9 0,000 0,04637056 0,09511611 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,04637056 0,09503632 ! renal water homeostasis GO:0003091 15 9 0,000 0,04637056 0,09495665 ! postreplication repair GO:0006301 25 9 0,000 0,04637056 0,09487713 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,04637056 0,09479773 ! icosanoid secretion GO:0032309 15 9 0,000 0,04637056 0,09471847 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,04637056 0,09463934 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,04637056 0,09456034 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,04637056 0,09448148 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,04637056 0,09440274 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,04637056 0,09432414 ! sterol catabolic process GO:0016127 14 9 0,000 0,04637056 0,09424566 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,04637056 0,09416732 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,04637056 0,09408911 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,04637056 0,09401103 ! S phase GO:0051320 10 9 0,000 0,04637056 0,09393308 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,04637056 0,09385525 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 0,04637056 0,09377756 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,04637056 0,09369999 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,04637056 0,09362255 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,04637056 0,09354524 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,04637056 0,09346806 ! purine base metabolic process GO:0006144 25 9 0,000 0,04637056 0,09339101 ! pigment granule transport GO:0051904 17 9 0,000 0,04637056 0,09331408 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,04637056 0,09323728 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,04637056 0,0931606 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,04637056 0,09308405 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,04637056 0,09300763 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,04637056 0,09293133 ! mitochondrion localization GO:0051646 18 9 0,000 0,04637056 0,09285516 ! ear development GO:0043583 114 66 1,000 0,04741631 0,09487145 ! regulation of lipid metabolic process GO:0019216 132 66 1,000 0,04741631 0,09479381 ! gonad development GO:0008406 115 66 1,000 0,04741631 0,0947163 ! chromosome segregation GO:0007059 127 67 1,000 0,04871028 0,09722158 ! positive regulation of T cell activation GO:0050870 124 68 1,000 0,05001701 0,09974821 ! viral reproduction GO:0016032 142 68 1,000 0,05001701 0,09966685 ! developmental maturation GO:0021700 128 69 1,000 0,05133633 0,10221243 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,05138896 0,1022339 ! regulation of developmental growth GO:0048638 16 10 0,000 0,05138896 0,10215072 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 0,000 0,05138896 0,10206767 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,05138896 0,10198475 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,05138896 0,10190197 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,05138896 0,10181933 ! associative learning GO:0008306 21 10 0,000 0,05138896 0,10173682 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,05138896 0,10165444 ! phosphate transport GO:0006817 24 10 0,000 0,05138896 0,10157219 ! cell volume homeostasis GO:0006884 17 10 0,000 0,05138896 0,10149008 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,05138896 0,1014081 ! CTP metabolic process GO:0046036 11 10 0,000 0,05138896 0,10132626 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 0,05138896 0,10124454 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,05138896 0,10116296 ! GTP metabolic process GO:0046039 11 10 0,000 0,05138896 0,10108151 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,05138896 0,10100019 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,05138896 0,100919 ! social behavior GO:0035176 29 10 0,000 0,05138896 0,10083794 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,05138896 0,10075701 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,05138896 0,10067621 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,05138896 0,10059554 ! androgen metabolic process GO:0008209 17 10 0,000 0,05138896 0,100515 ! phospholipid efflux GO:0033700 19 10 0,000 0,05138896 0,10043458 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,05138896 0,1003543 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,05138896 0,10027415 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,05138896 0,10019412 ! lung alveolus development GO:0048286 26 10 0,000 0,05138896 0,10011422 ! pathogenesis GO:0009405 17 10 0,000 0,05138896 0,10003445 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,05138896 0,0999548 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 0,05138896 0,09987528 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,05138896 0,09979589 ! endoderm development GO:0007492 18 10 0,000 0,05138896 0,09971662 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,05138896 0,09963748 ! arginine catabolic process GO:0006527 17 10 0,000 0,05138896 0,09955847 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,05138896 0,09947958 ! proline metabolic process GO:0006560 13 10 0,000 0,05138896 0,09940082 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,05138896 0,09932218 GO:0005978|glycogen biosynthetic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,05138896 0,09924366 ! V(D)J recombination GO:0033151 34 10 0,000 0,05138896 0,09916527 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,05138896 0,099087 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,05138896 0,09900886 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,05138896 0,09893084 ! B cell proliferation GO:0042100 19 10 0,000 0,05138896 0,09885294 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,05138896 0,09877516 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,05138896 0,09869751 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,05138896 0,09861998 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,05138896 0,09854257 ! ruffle organization GO:0031529 17 10 0,000 0,05138896 0,09846528 ! epithelial cell development GO:0002064 21 10 0,000 0,05138896 0,09838811 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,05138896 0,09831107 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,05138896 0,09823414 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,05138896 0,09815733 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,05138896 0,09808065 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,05138896 0,09800408 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,05138896 0,09792764 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 13 10 0,000 0,05138896 0,09785131 ! regulation of bone resorption GO:0045124 25 10 0,000 0,05138896 0,0977751 ! protein heterooligomerization GO:0051291 17 10 0,000 0,05138896 0,09769901 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,05138896 0,09762304 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,05138896 0,09754719 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,05138896 0,09747145 ! segment specification GO:0007379 15 10 0,000 0,05138896 0,09739583 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,05138896 0,09732033 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 0,000 0,05138896 0,09724495 ! blastoderm segmentation GO:0007350 19 10 0,000 0,05138896 0,09716968 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,05138896 0,09709453 ! response to dsRNA GO:0043331 23 10 0,000 0,05138896 0,0970195 ! DNA ligation GO:0006266 18 10 0,000 0,05138896 0,09694458 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,05138896 0,09686978 ! melanosome localization GO:0032400 16 10 0,000 0,05138896 0,09679509 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,05138896 0,09672052 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,05138896 0,09664606 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,05138896 0,09657172 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,05138896 0,09649749 ! induction of an organ GO:0001759 17 10 0,000 0,05138896 0,09642337 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,05138896 0,09634937 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,05138896 0,09627548 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,05138896 0,09620171 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,05138896 0,09612805 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,05138896 0,0960545 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,05138896 0,09598106 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,05138896 0,09590774 ! salivary gland development GO:0007431 28 10 0,000 0,05138896 0,09583453 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,05138896 0,09576143 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,05138896 0,09568844 ! midbrain development GO:0030901 14 10 0,000 0,05138896 0,09561556 ! musculoskeletal movement GO:0050881 16 10 0,000 0,05138896 0,09554279 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,05138896 0,09547014 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,05138896 0,09539759 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,05138896 0,09532516 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,05138896 0,09525283 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,05138896 0,09518061 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,05138896 0,09510851 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,05138896 0,09503651 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,05138896 0,09496462 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 0,000 0,05138896 0,09489284 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 24 10 0,000 0,05138896 0,09482117 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,05138896 0,09474961 ! blastocyst formation GO:0001825 18 10 0,000 0,05138896 0,09467815 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,05138896 0,09460681 ! cerebellar cortex development GO:0021695 16 10 0,000 0,05138896 0,09453557 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,05138896 0,09446443 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,05138896 0,09439341 ! response to nicotine GO:0035094 20 10 0,000 0,05138896 0,09432249 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,05138896 0,09425167 ! germ cell development GO:0007281 133 70 1,000 0,05266806 0,09652519 ! activation of immune response GO:0002253 120 70 1,000 0,05266806 0,09645283 ! protein maturation by peptide bond cleavage GO:0051605 118 70 1,000 0,05266806 0,09638058 ! cell cycle checkpoint GO:0000075 145 71 1,000 0,05401206 0,09876606 ! B cell activation GO:0042113 179 72 1,000 0,05536814 0,10117005 ! regulation of MAPKKK cascade GO:0043408 157 72 1,000 0,05536814 0,10109444 ! negative regulation of muscle development GO:0048635 27 11 0,000 0,05638109 0,10286706 ! respiratory burst GO:0045730 17 11 0,000 0,05638109 0,1027903 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,05638109 0,10271365 ! neuron fate specification GO:0048665 18 11 0,000 0,05638109 0,10263711 ! telencephalon cell migration GO:0022029 23 11 0,000 0,05638109 0,10256068 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,05638109 0,10248437 ! thyroid gland development GO:0030878 26 11 0,000 0,05638109 0,10240818 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 0,000 0,05638109 0,10233209 ! synapsis GO:0007129 14 11 0,000 0,05638109 0,10225612 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,05638109 0,10218027 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,05638109 0,10210452 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 0,000 0,05638109 0,10202889 ! response to pain GO:0048265 27 11 0,000 0,05638109 0,10195337 ! blood vessel remodeling GO:0001974 30 11 0,000 0,05638109 0,10187796 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 0,000 0,05638109 0,10180266 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 23 11 0,000 0,05638109 0,10172747 ! bone resorption GO:0045453 16 11 0,000 0,05638109 0,1016524 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,05638109 0,10157743 ! peptide or protein amino-terminal blocking GO:0018409 22 11 0,000 0,05638109 0,10150258 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,05638109 0,10142783 ! melanocyte differentiation GO:0030318 20 11 0,000 0,05638109 0,1013532 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,05638109 0,10127868 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,05638109 0,10120426 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,05638109 0,10112996 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,05638109 0,10105576 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,05638109 0,10098167 ! UV protection GO:0009650 20 11 0,000 0,05638109 0,10090769 ! adult heart development GO:0007512 16 11 0,000 0,05638109 0,10083382 ! chondrocyte differentiation GO:0002062 27 11 0,000 0,05638109 0,10076006 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,05638109 0,1006864 ! macroautophagy GO:0016236 19 11 0,000 0,05638109 0,10061286 ! temperature homeostasis GO:0001659 18 11 0,000 0,05638109 0,10053942 ! behavioral fear response GO:0001662 27 11 0,000 0,05638109 0,10046608 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,05638109 0,10039286 ! negative regulation of ossification GO:0030279 27 11 0,000 0,05638109 0,10031974 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,05638109 0,10024672 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,05638109 0,10017382 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 0,05638109 0,10010102 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,05638109 0,10002832 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,05638109 0,09995573 ! regulation of organ growth GO:0046620 14 11 0,000 0,05638109 0,09988325 ! pigment granule localization GO:0051875 20 11 0,000 0,05638109 0,09981087 ! vasoconstriction GO:0042310 20 11 0,000 0,05638109 0,09973859 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,05638109 0,09966642 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,05638109 0,09959436 ! embryonic axis specification GO:0000578 19 11 0,000 0,05638109 0,0995224 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,05638109 0,09945054 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,05638109 0,09937879 ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,05638109 0,09930714 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,05638109 0,09923559 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,05638109 0,09916415 ! prophase GO:0051324 17 11 0,000 0,05638109 0,0990928 ! neuroblast proliferation GO:0007405 25 11 0,000 0,05638109 0,09902157 ! nucleosome positioning GO:0016584 15 11 0,000 0,05638109 0,09895043 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,05638109 0,0988794 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,05638109 0,09880846 ! acid secretion GO:0046717 20 11 0,000 0,05638109 0,09873763 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,05638109 0,0986669 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,05638109 0,09859628 ! positive regulation of leukocyte migration GO:0002687 28 11 0,000 0,05638109 0,09852575 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,05638109 0,09845532 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,05638109 0,098385 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,05638109 0,09831477 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 0,05638109 0,09824465 ! cholesterol efflux GO:0033344 21 11 0,000 0,05638109 0,09817462 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,05638109 0,0981047 ! negative regulation of glucose import GO:0046325 18 11 0,000 0,05638109 0,09803487 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 26 11 0,000 0,05638109 0,09796515 ! embryonic gut development GO:0048566 19 11 0,000 0,05638109 0,09789552 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,05638109 0,09782599 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,05638109 0,09775656 ! activation of innate immune response GO:0002218 16 11 0,000 0,05638109 0,09768723 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,05638109 0,097618 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,05638109 0,09754887 ! prepulse inhibition GO:0060134 18 11 0,000 0,05638109 0,09747983 ! sequestering of metal ion GO:0051238 15 11 0,000 0,05638109 0,09741089 ! nucleus localization GO:0051647 22 11 0,000 0,05638109 0,09734205 ! regulation of immune effector process GO:0002697 156 73 1,000 0,05673615 0,09788588 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 1,000 0,05811593 0,10019563 ! reproductive structure development GO:0048608 131 75 1,000 0,05950731 0,10252211 ! phosphoinositide-mediated signaling GO:0048015 141 75 1,000 0,05950731 0,10244986 ! learning or memory GO:0007611 161 76 1,000 0,06091014 0,10479117 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 1,000 0,06091014 0,10471743 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,06134708 0,10539446 ! positive regulation of cellular catabolic process GO:0031331 34 12 0,000 0,06134708 0,1053204 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,06134708 0,10524644 ! virus-host interaction GO:0019048 30 12 0,000 0,06134708 0,10517258 ! regulation of positive chemotaxis GO:0050926 22 12 0,000 0,06134708 0,10509883 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,06134708 0,10502518 ! protein complex disassembly GO:0043241 28 12 0,000 0,06134708 0,10495163 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,06134708 0,10487819 ! regulation of cell projection assembly GO:0060491 33 12 0,000 0,06134708 0,10480484 ! hippocampus development GO:0021766 29 12 0,000 0,06134708 0,10473161 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 0,000 0,06134708 0,10465847 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,06134708 0,10458543 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,06134708 0,1045125 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,06134708 0,10443967 ! ventral spinal cord development GO:0021517 25 12 0,000 0,06134708 0,10436694 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,06134708 0,10429431 ! drug transport GO:0015893 16 12 0,000 0,06134708 0,10422179 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,06134708 0,10414936 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,06134708 0,10407703 ! polyamine metabolic process GO:0006595 18 12 0,000 0,06134708 0,10400481 ! focal adhesion formation GO:0048041 37 12 0,000 0,06134708 0,10393268 ! mitotic spindle organization GO:0007052 23 12 0,000 0,06134708 0,10386066 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,06134708 0,10378873 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,06134708 0,1037169 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,06134708 0,10364518 ! lipid digestion GO:0044241 21 12 0,000 0,06134708 0,10357355 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,06134708 0,10350202 ! entry into host cell GO:0030260 34 12 0,000 0,06134708 0,10343059 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,06134708 0,10335926 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,06134708 0,10328803 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,06134708 0,10321689 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,06134708 0,10314585 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,06134708 0,10307492 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,06134708 0,10300407 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,06134708 0,10293333 ! snRNA metabolic process GO:0016073 30 12 0,000 0,06134708 0,10286268 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,06134708 0,10279213 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,06134708 0,10272168 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,06134708 0,10265132 ! cranial nerve development GO:0021545 23 12 0,000 0,06134708 0,10258106 ! fucose catabolic process GO:0019317 25 12 0,000 0,06134708 0,10251089 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,06134708 0,10244083 ! histone acetylation GO:0016573 27 12 0,000 0,06134708 0,10237085 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,06134708 0,10230097 ! autonomic nervous system development GO:0048483 24 12 0,000 0,06134708 0,10223119 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 0,06134708 0,1021615 ! zymogen activation GO:0031638 18 12 0,000 0,06134708 0,10209191 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,06134708 0,10202241 ! T cell homeostasis GO:0043029 28 12 0,000 0,06134708 0,10195301 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,06134708 0,1018837 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,06134708 0,10181449 ! regulation of leukocyte migration GO:0002685 29 12 0,000 0,06134708 0,10174537 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,06134708 0,10167634 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,06134708 0,10160741 ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 0,000 0,06134708 0,10153857 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,06134708 0,10146982 ! defense response to fungus GO:0050832 15 12 0,000 0,06134708 0,10140117 ! developmental induction GO:0031128 22 12 0,000 0,06134708 0,10133261 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 21 12 0,000 0,06134708 0,10126414 ! lamellipodium assembly GO:0030032 24 12 0,000 0,06134708 0,10119576 ! response to cold GO:0009409 17 12 0,000 0,06134708 0,10112748 ! regulation of synapse organization GO:0050807 18 12 0,000 0,06134708 0,10105929 ! localization within membrane GO:0051668 26 12 0,000 0,06134708 0,10099119 ! cytosolic calcium ion homeostasis GO:0051480 149 77 1,000 0,06232426 0,10253075 ! positive regulation of lymphocyte activation GO:0051251 142 78 1,000 0,06374951 0,10480488 ! blood coagulation GO:0007596 151 79 1,000 0,06518574 0,10709399 GO:0050817|coagulation, ! protein oligomerization GO:0051259 149 79 1,000 0,06518574 0,10702202 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,06628708 0,10875712 ! cGMP metabolic process GO:0046068 18 13 0,000 0,06628708 0,10868413 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,06628708 0,10861123 ! regulation of chemokine production GO:0032642 18 13 0,000 0,06628708 0,10853844 ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,06628708 0,10846574 ! peroxisomal transport GO:0043574 28 13 0,000 0,06628708 0,10839314 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,06628708 0,10832063 ! cartilage condensation GO:0001502 22 13 0,000 0,06628708 0,10824823 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,06628708 0,10817592 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,06628708 0,1081037 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,06628708 0,10803159 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,06628708 0,10795957 ! endocrine pancreas development GO:0031018 25 13 0,000 0,06628708 0,10788764 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,06628708 0,10781581 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,06628708 0,10774408 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,06628708 0,10767244 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,06628708 0,1076009 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,06628708 0,10752945 ! methionine metabolic process GO:0006555 31 13 0,000 0,06628708 0,10745809 ! plasma membrane organization GO:0007009 27 13 0,000 0,06628708 0,10738684 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,06628708 0,10731567 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,06628708 0,1072446 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,06628708 0,10717363 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! cytokine metabolic process GO:0042107 24 13 0,000 0,06628708 0,10710274 ! exocrine system development GO:0035272 34 13 0,000 0,06628708 0,10703196 ! monoamine transport GO:0015844 21 13 0,000 0,06628708 0,10696126 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 0,000 0,06628708 0,10689066 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! L-glutamate transport GO:0015813 30 13 0,000 0,06628708 0,10682015 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,06628708 0,10674974 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,06628708 0,10667941 ! protein homotetramerization GO:0051289 24 13 0,000 0,06628708 0,10660918 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,06628708 0,10653904 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,06628708 0,106469 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,06628708 0,10639905 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,06628708 0,10632918 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,06628708 0,10625941 ! regulation of monooxygenase activity GO:0032768 35 13 0,000 0,06628708 0,10618974 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,06628708 0,10612015 ! histone methylation GO:0016571 29 13 0,000 0,06628708 0,10605065 ! chromatin silencing GO:0006342 29 13 0,000 0,06628708 0,10598125 ! gland morphogenesis GO:0022612 31 13 0,000 0,06628708 0,10591193 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,06628708 0,10584271 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 0,06628708 0,10577358 ! regulation of epidermis development GO:0045682 19 13 0,000 0,06628708 0,10570454 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,06628708 0,10563558 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,06628708 0,10556672 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,06628708 0,10549795 ! spleen development GO:0048536 24 13 0,000 0,06628708 0,10542926 ! regulation of mRNA stability GO:0043488 32 13 0,000 0,06628708 0,10536067 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,06628708 0,10529216 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,06628708 0,10522375 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,06628708 0,10515542 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,06628708 0,10508718 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,06628708 0,10501903 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,06628708 0,10495097 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,06628708 0,104883 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,06628708 0,10481511 ! insulin secretion GO:0030073 24 13 0,000 0,06628708 0,10474731 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,06628708 0,1046796 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 0,06628708 0,10461198 ! acrosome reaction GO:0007340 19 13 0,000 0,06628708 0,10454445 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,06628708 0,104477 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,06628708 0,10440964 ! development of primary sexual characteristics GO:0045137 143 80 1,000 0,0666328 0,10488655 ! muscle cell differentiation GO:0042692 178 81 1,000 0,06809053 0,10711214 ! positive regulation of phosphorylation GO:0042327 149 81 1,000 0,06809053 0,10704322 ! protein import into nucleus GO:0006606 174 82 1,000 0,06955878 0,10928109 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 1,000 0,0710374 0,11153238 GO:0045937|positive regulation of phosphate metabolic process, ! nuclear import GO:0051170 177 83 1,000 0,0710374 0,11146074 ! rRNA transcription GO:0009303 28 14 0,000 0,07120122 0,11164608 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,07120122 0,11157447 GO:0046579|positive regulation of Ras protein signal transduction, ! water transport GO:0006833 21 14 0,000 0,07120122 0,11150294 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,07120122 0,11143151 ! non-recombinational repair GO:0000726 29 14 0,000 0,07120122 0,11136017 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,07120122 0,11128893 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,07120122 0,11121777 ! hair follicle morphogenesis GO:0031069 27 14 0,000 0,07120122 0,1111467 ! RNA polyadenylation GO:0043631 32 14 0,000 0,07120122 0,11107573 ! lipid localization GO:0010876 32 14 0,000 0,07120122 0,11100485 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 0,07120122 0,11093405 ! regulated secretory pathway GO:0045055 24 14 0,000 0,07120122 0,11086335 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,07120122 0,11079273 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,07120122 0,11072221 ! arginine metabolic process GO:0006525 21 14 0,000 0,07120122 0,11065178 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,07120122 0,11058143 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,07120122 0,11051118 ! regulation of heart rate GO:0002027 25 14 0,000 0,07120122 0,11044101 ! fear response GO:0042596 34 14 0,000 0,07120122 0,11037093 ! organic alcohol transport GO:0015850 29 14 0,000 0,07120122 0,11030095 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 0,000 0,07120122 0,11023105 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,07120122 0,11016124 ! neutral amino acid transport GO:0015804 28 14 0,000 0,07120122 0,11009151 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,07120122 0,11002188 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,07120122 0,10995233 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,07120122 0,10988288 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,07120122 0,10981351 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,07120122 0,10974422 ! ribosome assembly GO:0042255 18 14 0,000 0,07120122 0,10967503 ! cerebellum development GO:0021549 23 14 0,000 0,07120122 0,10960592 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,07120122 0,1095369 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,07120122 0,10946796 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,07120122 0,10939911 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,07120122 0,10933035 ! NADP metabolic process GO:0006739 24 14 0,000 0,07120122 0,10926168 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,07120122 0,10919309 ! oxygen transport GO:0015671 22 14 0,000 0,07120122 0,10912459 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,07120122 0,10905617 ! male genitalia development GO:0030539 26 14 0,000 0,07120122 0,10898784 ! regulation of RNA stability GO:0043487 33 14 0,000 0,07120122 0,10891959 ! regulation of axon extension GO:0030516 43 14 0,000 0,07120122 0,10885143 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,07120122 0,10878336 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 0,07120122 0,10871537 ! response to metal ion GO:0010038 158 84 1,000 0,07252625 0,11066935 ! response to nutrient GO:0007584 135 84 1,000 0,07252625 0,11060027 ! hemostasis GO:0007599 165 85 1,000 0,07402518 0,11281566 ! negative regulation of transport GO:0051051 164 85 1,000 0,07402518 0,11274533 ! regulation of neuron differentiation GO:0045664 187 85 1,000 0,07402518 0,11267508 ! positive regulation of cell activation GO:0050867 161 86 1,000 0,07553403 0,11490015 GO:0002696|positive regulation of leukocyte activation, ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,07608964 0,1156733 ! lactation GO:0007595 30 15 0,000 0,07608964 0,11560136 ! N-terminal protein amino acid modification GO:0031365 30 15 0,000 0,07608964 0,11552951 ! reproductive cellular process GO:0048610 22 15 0,000 0,07608964 0,11545776 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,07608964 0,11538609 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,07608964 0,11531451 ! superoxide anion generation GO:0042554 22 15 0,000 0,07608964 0,11524302 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,07608964 0,11517162 ! negative regulation of bone remodeling GO:0046851 34 15 0,000 0,07608964 0,1151003 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,07608964 0,11502908 ! copper ion transport GO:0006825 22 15 0,000 0,07608964 0,11495794 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,07608964 0,11488689 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,07608964 0,11481593 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,07608964 0,11474506 ! sulfate transport GO:0008272 27 15 0,000 0,07608964 0,11467427 ! response to cAMP GO:0051591 25 15 0,000 0,07608964 0,11460357 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,07608964 0,11453296 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,07608964 0,11446243 ! response to hexose stimulus GO:0009746 25 15 0,000 0,07608964 0,11439199 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,07608964 0,11432164 ! vesicle coating GO:0006901 38 15 0,000 0,07608964 0,11425138 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 0,07608964 0,1141812 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 0,07608964 0,1141111 ! regulation of exocytosis GO:0017157 26 15 0,000 0,07608964 0,1140411 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,07608964 0,11397118 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,07608964 0,11390134 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,07608964 0,11383159 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,07608964 0,11376193 ! regulation of vasodilation GO:0042312 27 15 0,000 0,07608964 0,11369235 ! histone deacetylation GO:0016575 24 15 0,000 0,07608964 0,11362285 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,07608964 0,11355344 ! water homeostasis GO:0030104 28 15 0,000 0,07608964 0,11348412 ! cofactor transport GO:0051181 30 15 0,000 0,07608964 0,11341488 ! muscle maintenance GO:0046716 26 15 0,000 0,07608964 0,11334573 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,07608964 0,11327665 ! intestinal absorption GO:0050892 31 15 0,000 0,07608964 0,11320767 ! dopamine metabolic process GO:0042417 35 15 0,000 0,07608964 0,11313876 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,07608964 0,11306994 ! heme biosynthetic process GO:0006783 33 15 0,000 0,07608964 0,11300121 ! cell killing GO:0001906 32 15 0,000 0,07608964 0,11293256 ! lymphocyte homeostasis GO:0002260 33 15 0,000 0,07608964 0,11286399 ! epithelial to mesenchymal transition GO:0001837 30 15 0,000 0,07608964 0,1127955 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,07608964 0,1127271 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,07608964 0,11265878 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,07608964 0,11259054 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,07608964 0,11252239 ! alcohol catabolic process GO:0046164 142 87 1,000 0,07705267 0,11387761 ! regulation of protein transport GO:0051223 165 87 1,000 0,07705267 0,11380876 GO:0070201|regulation of establishment of protein localization, ! one-carbon metabolic process GO:0006730 167 88 1,000 0,07858096 0,11599594 ! protein localization in nucleus GO:0034504 192 89 1,000 0,08011874 0,1181945 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,08095246 0,11935236 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,08095246 0,11928038 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,08095246 0,11920848 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,08095246 0,11913667 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,08095246 0,11906494 ! bone remodeling GO:0046849 28 16 0,000 0,08095246 0,1189933 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,08095246 0,11892175 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,08095246 0,11885028 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,08095246 0,1187789 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,08095246 0,1187076 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,08095246 0,11863639 ! startle response GO:0001964 28 16 0,000 0,08095246 0,11856527 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,08095246 0,11849423 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,08095246 0,11842327 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,08095246 0,1183524 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,08095246 0,11828162 ! protein polyubiquitination GO:0000209 41 16 0,000 0,08095246 0,11821092 ! glutamate metabolic process GO:0006536 25 16 0,000 0,08095246 0,1181403 ! pituitary gland development GO:0021983 30 16 0,000 0,08095246 0,11806977 ! response to osmotic stress GO:0006970 27 16 0,000 0,08095246 0,11799932 ! lysosomal transport GO:0007041 31 16 0,000 0,08095246 0,11792896 ! fructose metabolic process GO:0006000 25 16 0,000 0,08095246 0,11785868 ! L-amino acid transport GO:0015807 33 16 0,000 0,08095246 0,11778848 ! stem cell development GO:0048864 46 16 0,000 0,08095246 0,11771837 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,08095246 0,11764834 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,08095246 0,1175784 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,08095246 0,11750854 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,08095246 0,11743876 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,08095246 0,11736906 ! positive regulation of protein import into nucleus GO:0042307 34 16 0,000 0,08095246 0,11729945 ! DNA replication initiation GO:0006270 28 16 0,000 0,08095246 0,11722991 ! neuron recognition GO:0008038 40 16 0,000 0,08095246 0,11716047 ! mRNA splice site selection GO:0006376 44 16 0,000 0,08095246 0,1170911 ! tissue regeneration GO:0042246 27 16 0,000 0,08095246 0,11702181 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,08095246 0,11695261 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,08095246 0,11688349 ! negative regulation of tissue remodeling GO:0034104 37 16 0,000 0,08095246 0,11681445 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,08095246 0,11674549 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,08095246 0,11667662 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,08095246 0,11660782 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,08095246 0,11653911 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,08095246 0,11647047 ! peptide hormone processing GO:0016486 27 16 0,000 0,08095246 0,11640192 ! response to inorganic substance GO:0010035 173 90 1,000 0,08166589 0,11735869 ! oxidative phosphorylation GO:0006119 152 90 1,000 0,08166589 0,11728969 ! positive regulation of protein modification process GO:0031401 156 90 1,000 0,08166589 0,11722078 ! response to unfolded protein GO:0006986 139 90 1,000 0,08166589 0,11715195 ! ossification GO:0001503 205 91 1,000 0,08322225 0,11931454 ! bone development GO:0060348 206 92 1,000 0,0847877 0,1214876 ! metencephalon development GO:0022037 32 17 0,000 0,08578983 0,12285143 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,08578983 0,12277947 ! negative regulation of cell cycle process GO:0010948 35 17 0,000 0,08578983 0,12270758 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,08578983 0,12263578 ! signal complex assembly GO:0007172 47 17 0,000 0,08578983 0,12256406 ! filopodium assembly GO:0046847 42 17 0,000 0,08578983 0,12249243 ! endothelial cell migration GO:0043542 31 17 0,000 0,08578983 0,12242088 ! gene silencing by RNA GO:0031047 38 17 0,000 0,08578983 0,12234941 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,08578983 0,12227803 ! glial cell development GO:0021782 28 17 0,000 0,08578983 0,12220673 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,08578983 0,12213552 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,08578983 0,12206438 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 0,000 0,08578983 0,12199333 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,08578983 0,12192237 ! myoblast differentiation GO:0045445 50 17 0,000 0,08578983 0,12185148 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 0,000 0,08578983 0,12178068 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,08578983 0,12170996 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,08578983 0,12163932 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,08578983 0,12156876 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,08578983 0,12149829 ! negative regulation of microtubule depolymerization GO:0007026 50 17 0,000 0,08578983 0,1214279 GO:0031114|regulation of microtubule depolymerization, ! NAD metabolic process GO:0019674 33 17 0,000 0,08578983 0,12135758 ! membrane budding GO:0006900 42 17 0,000 0,08578983 0,12128735 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,08578983 0,12121721 ! regulation of protein binding GO:0043393 33 17 0,000 0,08578983 0,12114714 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,08578983 0,12107715 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,08578983 0,12100724 ! genitalia development GO:0048806 32 17 0,000 0,08578983 0,12093742 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,08578983 0,12086767 ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,08578983 0,12079801 ! neutrophil chemotaxis GO:0030593 29 17 0,000 0,08578983 0,12072843 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,08578983 0,12065892 ! steroid catabolic process GO:0006706 34 17 0,000 0,08578983 0,1205895 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,08578983 0,12052015 ! gas transport GO:0015669 26 17 0,000 0,08578983 0,12045089 ! organic cation transport GO:0015695 32 17 0,000 0,08578983 0,1203817 ! negative regulation of homeostatic process GO:0032845 36 17 0,000 0,08578983 0,1203126 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,08578983 0,12024357 ! regulation of cell morphogenesis GO:0022604 243 93 1,000 0,08636209 0,12097626 ! carbohydrate biosynthetic process GO:0016051 158 94 1,000 0,08794529 0,12312341 ! regulation of membrane potential GO:0042391 179 94 1,000 0,08794529 0,12305289 ! ATP biosynthetic process GO:0006754 197 95 1,000 0,08953716 0,12520852 ! positive regulation of protein complex assembly GO:0031334 34 18 0,000 0,09060187 0,12662492 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,09060187 0,12655252 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,09060187 0,1264802 ! limbic system development GO:0021761 40 18 0,000 0,09060187 0,12640797 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,09060187 0,12633582 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,09060187 0,12626375 ! adult walking behavior GO:0007628 36 18 0,000 0,09060187 0,12619177 ! patterning of blood vessels GO:0001569 43 18 0,000 0,09060187 0,12611986 ! heart looping GO:0001947 34 18 0,000 0,09060187 0,12604804 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,09060187 0,1259763 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,09060187 0,12590464 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,09060187 0,12583306 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,09060187 0,12576157 ! epidermis morphogenesis GO:0048730 43 18 0,000 0,09060187 0,12569015 ! glycine metabolic process GO:0006544 30 18 0,000 0,09060187 0,12561882 ! glutamine metabolic process GO:0006541 29 18 0,000 0,09060187 0,12554757 ! response to retinoic acid GO:0032526 31 18 0,000 0,09060187 0,12547639 ! cell-substrate junction assembly GO:0007044 56 18 0,000 0,09060187 0,1254053 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 0,000 0,09060187 0,12533429 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,09060187 0,12526336 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,09060187 0,12519251 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,09060187 0,12512174 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,09060187 0,12505105 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,09060187 0,12498044 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,09060187 0,12490991 GO:0046466|membrane lipid catabolic process, ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,09060187 0,12483946 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,09060187 0,12476909 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,09060187 0,12469879 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 0,000 0,09060187 0,12462858 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,09060187 0,12455845 ! detection of bacterium GO:0016045 22 18 0,000 0,09060187 0,12448839 ! nerve development GO:0021675 34 18 0,000 0,09060187 0,12441841 ! microspike assembly GO:0030035 46 18 0,000 0,09060187 0,12434852 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,09060187 0,1242787 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 0,000 0,09060187 0,12420896 ! sex differentiation GO:0007548 171 96 1,000 0,09113757 0,12487329 ! response to protein stimulus GO:0051789 158 96 1,000 0,09113757 0,1248033 ! transcription initiation GO:0006352 171 97 1,000 0,09274639 0,12693525 ! regulation of protein localization GO:0032880 188 97 1,000 0,09274639 0,12686418 ! forebrain development GO:0030900 210 98 1,000 0,09436348 0,1290039 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,09538871 0,13033256 ! positive regulation of translation GO:0045727 31 19 0,000 0,09538871 0,13025971 ! negative regulation of defense response GO:0031348 27 19 0,000 0,09538871 0,13018694 ! G1 phase of mitotic cell cycle GO:0000080 39 19 0,000 0,09538871 0,13011425 ! neuron maturation GO:0042551 46 19 0,000 0,09538871 0,13004164 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,09538871 0,12996911 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 0,09538871 0,12989667 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,09538871 0,1298243 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,09538871 0,12975202 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,09538871 0,12967981 ! inositol metabolic process GO:0006020 33 19 0,000 0,09538871 0,12960769 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,09538871 0,12953564 ! memory GO:0007613 34 19 0,000 0,09538871 0,12946368 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,09538871 0,12939179 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,09538871 0,12931999 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,09538871 0,12924826 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,09538871 0,12917662 ! cerebral cortex development GO:0021987 40 19 0,000 0,09538871 0,12910505 ! pigmentation during development GO:0048066 42 19 0,000 0,09538871 0,12903357 ! response to vitamin A GO:0033189 32 19 0,000 0,09538871 0,12896216 ! heme metabolic process GO:0042168 40 19 0,000 0,09538871 0,12889083 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,09538871 0,12881958 ! regulation of endothelial cell migration GO:0010594 45 19 0,000 0,09538871 0,12874841 ! response to fungus GO:0009620 26 19 0,000 0,09538871 0,12867732 ! peptide cross-linking GO:0018149 39 19 0,000 0,09538871 0,1286063 ! protein export from nucleus GO:0006611 40 19 0,000 0,09538871 0,12853537 ! heart process GO:0003015 32 19 0,000 0,09538871 0,12846451 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,09538871 0,12839373 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,09538871 0,12832303 ! visual learning GO:0008542 38 19 0,000 0,09538871 0,12825241 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,09538871 0,12818186 ! vitamin transport GO:0051180 31 19 0,000 0,09538871 0,12811139 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,09538871 0,128041 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,09538871 0,12797069 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,09538871 0,12790045 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,09538871 0,12783029 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,09538871 0,12776021 ! cilium assembly GO:0042384 38 19 0,000 0,09538871 0,1276902 ! peptide hormone secretion GO:0030072 32 19 0,000 0,09538871 0,12762027 ! skeletal muscle tissue development GO:0007519 223 100 1,000 0,09762196 0,13053664 GO:0060538|skeletal muscle organ development, ! positive regulation of immune response GO:0050778 175 100 1,000 0,09762196 0,13046523 ! protein secretion GO:0009306 45 20 0,000 0,10015049 0,13377127 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,10015049 0,13369817 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,10015049 0,13362515 ! positive regulation of ossification GO:0045778 50 20 0,000 0,10015049 0,13355221 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,10015049 0,13347935 ! phosphoinositide phosphorylation GO:0046854 40 20 0,000 0,10015049 0,13340657 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,10015049 0,13333387 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,10015049 0,13326125 ! protein amino acid acetylation GO:0006473 41 20 0,000 0,10015049 0,13318871 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 0,000 0,10015049 0,13311624 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,10015049 0,13304386 ! response to vitamin GO:0033273 36 20 0,000 0,10015049 0,13297155 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,10015049 0,13289932 ! regulation of carbohydrate metabolic process GO:0006109 37 20 0,000 0,10015049 0,13282717 GO:0010675|regulation of cellular carbohydrate metabolic process, ! forelimb morphogenesis GO:0035136 35 20 0,000 0,10015049 0,1327551 ! bile acid metabolic process GO:0008206 34 20 0,000 0,10015049 0,13268311 ! retinoid metabolic process GO:0001523 34 20 0,000 0,10015049 0,13261119 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 40 20 0,000 0,10015049 0,13253936 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,10015049 0,1324676 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,10015049 0,13239592 GO:0032392|DNA geometric change, ! cellular response to unfolded protein GO:0034620 35 20 0,000 0,10015049 0,13232431 GO:0030968|endoplasmic reticulum unfolded protein response, ! peptidyl-serine phosphorylation GO:0018105 44 20 0,000 0,10015049 0,13225279 ! actin filament bundle formation GO:0051017 47 20 0,000 0,10015049 0,13218134 ! body fluid secretion GO:0007589 33 20 0,000 0,10015049 0,13210996 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,10015049 0,13203867 ! peptide secretion GO:0002790 38 20 0,000 0,10015049 0,13196745 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,10015049 0,13189631 ! regulation of fatty acid metabolic process GO:0019217 45 20 0,000 0,10015049 0,13182524 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,10015049 0,13175426 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,10015049 0,13168334 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,10015049 0,13161251 ! cell-cell junction organization GO:0045216 43 20 0,000 0,10015049 0,13154175 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 0,000 0,10015049 0,13147107 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,10015049 0,13140046 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,10015049 0,13132993 ! regulation of glucose import GO:0046324 30 20 0,000 0,10015049 0,13125947 GO:0010827|regulation of glucose transport, ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,10015049 0,13118909 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,10015049 0,13111879 ! negative regulation of translation GO:0017148 32 20 0,000 0,10015049 0,13104856 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,10015049 0,1309784 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,10488734 0,13709994 ! hormone secretion GO:0046879 39 21 0,000 0,10488734 0,13702662 ! lipid phosphorylation GO:0046834 43 21 0,000 0,10488734 0,13695338 ! cAMP metabolic process GO:0046058 41 21 0,000 0,10488734 0,13688022 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,10488734 0,13680714 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,10488734 0,13673414 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,10488734 0,13666122 ! ovarian follicle development GO:0001541 39 21 0,000 0,10488734 0,13658837 ! smooth muscle contraction GO:0006939 48 21 0,000 0,10488734 0,1365156 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 0,000 0,10488734 0,13644291 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,10488734 0,13637029 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,10488734 0,13629775 ! plasma membrane fusion GO:0045026 33 21 0,000 0,10488734 0,13622529 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,10488734 0,13615291 GO:0006692|prostanoid metabolic process, ! regulation of vasoconstriction GO:0019229 40 21 0,000 0,10488734 0,1360806 ! sensory perception of pain GO:0019233 33 21 0,000 0,10488734 0,13600838 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,10488734 0,13593622 ! diencephalon development GO:0021536 36 21 0,000 0,10488734 0,13586415 ! collagen fibril organization GO:0030199 62 21 0,000 0,10488734 0,13579215 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,10488734 0,13572022 ! positive regulation of inflammatory response GO:0050729 41 21 0,000 0,10488734 0,13564837 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,10488734 0,1355766 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 0,10488734 0,13550491 ! collagen catabolic process GO:0030574 29 21 0,000 0,10488734 0,13543329 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,10488734 0,13536174 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,10488734 0,13529027 ! sperm-egg recognition GO:0035036 23 21 0,000 0,10488734 0,13521888 ! actin filament-based movement GO:0030048 47 21 0,000 0,10488734 0,13514756 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,10959939 0,1411446 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,10959939 0,14107024 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,10959939 0,14099595 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,10959939 0,14092174 GO:0034105|positive regulation of tissue remodeling, ! hindlimb morphogenesis GO:0035137 47 22 0,000 0,10959939 0,14084761 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,10959939 0,14077356 ! inactivation of MAPK activity GO:0000188 45 22 0,000 0,10959939 0,14069959 ! vacuolar transport GO:0007034 41 22 0,000 0,10959939 0,14062569 ! central nervous system neuron development GO:0021954 47 22 0,000 0,10959939 0,14055187 ! fucose metabolic process GO:0006004 44 22 0,000 0,10959939 0,14047813 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,10959939 0,14040446 ! ureteric bud development GO:0001657 50 22 0,000 0,10959939 0,14033088 ! stem cell differentiation GO:0048863 57 22 0,000 0,10959939 0,14025737 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,10959939 0,14018393 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 0,10959939 0,14011058 ! cytolysis GO:0019835 27 22 0,000 0,10959939 0,1400373 ! renal system process GO:0003014 42 22 0,000 0,10959939 0,13996409 ! vasodilation GO:0042311 40 22 0,000 0,10959939 0,13989097 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,10959939 0,13981792 ! positive regulation of locomotion GO:0040017 44 22 0,000 0,10959939 0,13974494 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! G1 phase GO:0051318 44 22 0,000 0,10959939 0,13967205 ! detection of chemical stimulus GO:0009593 42 22 0,000 0,10959939 0,13959922 ! positive regulation of intracellular transport GO:0032388 42 22 0,000 0,10959939 0,13952648 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,10959939 0,13945381 ! peptidyl-serine modification GO:0018209 50 22 0,000 0,10959939 0,13938121 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,10959939 0,13930869 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,10959939 0,13923625 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,10959939 0,13916388 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,10959939 0,13909159 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,10959939 0,13901937 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,10959939 0,13894723 ! gut development GO:0048565 44 22 0,000 0,10959939 0,13887516 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,10959939 0,13880317 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 0,000 0,10959939 0,13873125 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,10959939 0,1386594 ! protein stabilization GO:0050821 41 22 0,000 0,10959939 0,13858764 ! positive regulation of DNA replication GO:0045740 44 23 0,000 0,11428676 0,14444002 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,11428676 0,14436534 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,11428676 0,14429073 ! viral genome replication GO:0019079 44 23 0,000 0,11428676 0,1442162 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,11428676 0,14414175 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,11428676 0,14406737 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of chemotaxis GO:0050920 45 23 0,000 0,11428676 0,14399307 ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,11428676 0,14391885 ! regeneration GO:0031099 42 23 0,000 0,11428676 0,1438447 ! axis specification GO:0009798 43 23 0,000 0,11428676 0,14377063 ! visual behavior GO:0007632 46 23 0,000 0,11428676 0,14369664 ! regulation of cell-matrix adhesion GO:0001952 81 23 0,000 0,11428676 0,14362272 GO:0010810|regulation of cell-substrate adhesion, ! response to ethanol GO:0045471 47 23 0,000 0,11428676 0,14354888 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,11428676 0,14347511 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,11428676 0,14340142 ! peroxisome organization GO:0007031 43 23 0,000 0,11428676 0,14332781 ! lysosome organization GO:0007040 47 23 0,000 0,11428676 0,14325427 ! vesicle targeting GO:0006903 49 23 0,000 0,11428676 0,1431808 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,11428676 0,14310742 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,11428676 0,1430341 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,11428676 0,14296086 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,11428676 0,1428877 ! fatty acid transport GO:0015908 47 23 0,000 0,11428676 0,14281461 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,11428676 0,1427416 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,11428676 0,14266866 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,11428676 0,1425958 ! hormone transport GO:0009914 41 23 0,000 0,11428676 0,142523 ! cell-cell recognition GO:0009988 28 23 0,000 0,11428676 0,14245029 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,11428676 0,14237765 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,11428676 0,14230508 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,11428676 0,14223259 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,11894959 0,14796021 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 55 24 0,000 0,11894959 0,14788492 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,11894959 0,14780969 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,11894959 0,14773455 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,11894959 0,14765948 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,11894959 0,14758449 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 0,11894959 0,14750957 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,11894959 0,14743473 ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,11894959 0,14735997 ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,11894959 0,14728528 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,11894959 0,14721067 GO:0051693|actin filament capping, ! sex determination GO:0007530 48 24 0,000 0,11894959 0,14713613 ! regulation of viral reproduction GO:0050792 41 24 0,000 0,11894959 0,14706167 ! leukotriene metabolic process GO:0006691 47 24 0,000 0,11894959 0,14698728 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,11894959 0,14691297 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,11894959 0,14683874 ! membrane depolarization GO:0051899 45 24 0,000 0,11894959 0,14676458 ! pallium development GO:0021543 56 24 0,000 0,11894959 0,14669049 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,11894959 0,14661648 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,11894959 0,14654254 ! regulation of oxidoreductase activity GO:0051341 48 24 0,000 0,11894959 0,14646868 ! platelet activation GO:0030168 41 24 0,000 0,11894959 0,14639489 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,11894959 0,14632118 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,11894959 0,14624754 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,11894959 0,14617397 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,11894959 0,14610048 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,11894959 0,14602707 ! regulation of amine transport GO:0051952 41 24 0,000 0,11894959 0,14595372 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 0,000 0,11894959 0,14588045 ! positive regulation of fibroblast proliferation GO:0048146 48 25 0,000 0,12358801 0,15149298 ! myeloid leukocyte differentiation GO:0002573 46 25 0,000 0,12358801 0,151417 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,12358801 0,1513411 ! keratinization GO:0031424 37 25 0,000 0,12358801 0,15126528 ! vasculogenesis GO:0001570 49 25 0,000 0,12358801 0,15118954 ! vacuole organization GO:0007033 49 25 0,000 0,12358801 0,15111387 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,12358801 0,15103827 ! receptor metabolic process GO:0043112 53 25 0,000 0,12358801 0,15096275 ! chromosome condensation GO:0030261 48 25 0,000 0,12358801 0,15088731 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,12358801 0,15081194 ! regulation of behavior GO:0050795 48 25 0,000 0,12358801 0,15073665 ! interaction with host GO:0051701 66 25 0,000 0,12358801 0,15066143 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,12358801 0,15058629 ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,12358801 0,15051122 ! leukocyte homeostasis GO:0001776 50 25 0,000 0,12358801 0,15043622 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,12358801 0,15036131 ! liver development GO:0001889 55 25 0,000 0,12358801 0,15028646 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,12820213 0,1558198 ! molting cycle process GO:0022404 52 26 0,000 0,12820213 0,15574232 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,12820213 0,15566491 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,12820213 0,15558758 GO:0006479|protein amino acid methylation, ! regulation of transcription factor import into nucleus GO:0042990 58 26 0,000 0,12820213 0,15551033 ! spinal cord development GO:0021510 54 26 0,000 0,12820213 0,15543315 ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,12820213 0,15535605 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,12820213 0,15527903 ! digestive system process GO:0022600 49 26 0,000 0,12820213 0,15520208 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,12820213 0,15512521 ! regulation of cellular ketone metabolic process GO:0010565 51 26 0,000 0,12820213 0,15504842 ! osteoblast differentiation GO:0001649 63 26 0,000 0,12820213 0,1549717 ! coenzyme catabolic process GO:0009109 42 26 0,000 0,12820213 0,15489506 ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,12820213 0,15481849 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,12820213 0,154742 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,12820213 0,15466558 ! regulation of blood coagulation GO:0030193 46 26 0,000 0,12820213 0,15458924 ! positive regulation of nuclear division GO:0051785 41 26 0,000 0,12820213 0,15451298 GO:0045840|positive regulation of mitosis, ! regulation of osteoblast differentiation GO:0045667 68 26 0,000 0,12820213 0,15443679 ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,12820213 0,15436067 ! telomere organization GO:0032200 46 26 0,000 0,12820213 0,15428463 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,12820213 0,15420867 ! neural tube closure GO:0001843 58 26 0,000 0,12820213 0,15413278 GO:0060606|tube closure, ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,12820213 0,15405696 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,12820213 0,15398122 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,13279209 0,15941576 ! embryonic pattern specification GO:0009880 49 27 0,000 0,13279209 0,15933746 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,13279209 0,15925924 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,13279209 0,1591811 ! positive regulation of cell projection organization GO:0031346 66 27 0,000 0,13279209 0,15910303 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,13279209 0,15902504 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,13279209 0,15894712 ! iron ion transport GO:0006826 65 27 0,000 0,13279209 0,15886928 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,13279209 0,15879152 ! superoxide metabolic process GO:0006801 41 27 0,000 0,13279209 0,15871383 ! tube lumen formation GO:0035148 59 27 0,000 0,13279209 0,15863622 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,13279209 0,15855869 ! regulation of endothelial cell proliferation GO:0001936 60 27 0,000 0,13279209 0,15848123 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,13279209 0,15840385 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,13279209 0,15832654 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 0,000 0,13735801 0,16369055 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,13735801 0,16361074 ! protein amino acid acylation GO:0043543 59 28 0,000 0,13735801 0,16353101 ! vesicle docking GO:0048278 55 28 0,000 0,13735801 0,16345135 ! circadian rhythm GO:0007623 56 28 0,000 0,13735801 0,16337178 ! dendrite development GO:0016358 67 28 0,000 0,13735801 0,16329228 ! fat cell differentiation GO:0045444 57 28 0,000 0,13735801 0,16321285 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,13735801 0,16313351 ! sperm motility GO:0030317 37 28 0,000 0,13735801 0,16305424 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,13735801 0,16297505 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,13735801 0,16289594 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,13735801 0,1628169 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,13735801 0,16273794 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,13735801 0,16265905 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,13735801 0,16258025 ! glutathione metabolic process GO:0006749 42 28 0,000 0,13735801 0,16250151 ! lipid oxidation GO:0034440 48 28 0,000 0,13735801 0,16242286 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,13735801 0,16234428 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,13735801 0,16226578 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 0,000 0,14190002 0,16755039 ! translational initiation GO:0006413 66 29 0,000 0,14190002 0,16746945 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,14190002 0,16738858 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,14190002 0,1673078 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! autophagy GO:0006914 47 29 0,000 0,14190002 0,16722709 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,14190002 0,16714646 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,14190002 0,16706591 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 0,000 0,14190002 0,16698543 ! somitogenesis GO:0001756 52 29 0,000 0,14190002 0,16690504 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,14190002 0,16682472 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,14190002 0,16674447 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,14190002 0,16666431 ! phenol metabolic process GO:0018958 56 30 0,000 0,14641825 0,17188841 ! negative regulation of protein complex assembly GO:0031333 68 30 0,000 0,14641825 0,17180585 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,14641825 0,17172337 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,14641825 0,17164097 ! sensory perception of taste GO:0050909 41 30 0,000 0,14641825 0,17155865 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,14641825 0,1714764 ! acute-phase response GO:0006953 50 30 0,000 0,14641825 0,17139424 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,14641825 0,17131215 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,14641825 0,17123015 ! negative regulation of protein kinase cascade GO:0010741 72 30 0,000 0,14641825 0,17114822 ! determination of left/right symmetry GO:0007368 53 30 0,000 0,14641825 0,17106637 ! cell fate determination GO:0001709 64 30 0,000 0,14641825 0,1709846 ! phospholipid transport GO:0015914 65 30 0,000 0,14641825 0,1709029 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,14641825 0,17082129 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,14641825 0,17073975 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,14641825 0,17065829 ! negative regulation of transcription regulator activity GO:0090048 57 30 0,000 0,14641825 0,17057691 GO:0043433|negative regulation of transcription factor activity, ! regulation of coagulation GO:0050818 52 30 0,000 0,14641825 0,1704956 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,15091281 0,17564554 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,15091281 0,1755619 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,15091281 0,17547834 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,15091281 0,17539486 ! cell junction assembly GO:0034329 85 31 0,000 0,15091281 0,17531145 ! regulation of innate immune response GO:0045088 57 31 0,000 0,15091281 0,17522813 ! ovulation cycle process GO:0022602 55 31 0,000 0,15091281 0,17514489 ! peptide transport GO:0015833 60 31 0,000 0,15091281 0,17506172 ! male gonad development GO:0008584 56 31 0,000 0,15091281 0,17497864 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,15091281 0,17489563 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 0,000 0,15091281 0,1748127 ! natural killer cell activation GO:0030101 50 31 0,000 0,15091281 0,17472985 ! cofactor catabolic process GO:0051187 54 31 0,000 0,15091281 0,17464708 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,15091281 0,17456439 ! eye morphogenesis GO:0048592 65 31 0,000 0,15091281 0,17448177 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,15538383 0,17956608 ! collagen metabolic process GO:0032963 49 32 0,000 0,15538383 0,17948118 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,15538383 0,17939636 ! spindle organization GO:0007051 50 32 0,000 0,15538383 0,17931161 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,15538383 0,17922695 ! metanephros development GO:0001656 81 32 0,000 0,15538383 0,17914237 ! regulation of protein import into nucleus GO:0042306 69 32 0,000 0,15538383 0,17905787 ! mesoderm formation GO:0001707 73 32 0,000 0,15538383 0,17897345 ! ovulation cycle GO:0042698 57 32 0,000 0,15538383 0,17888911 ! BMP signaling pathway GO:0030509 71 32 0,000 0,15538383 0,17880485 ! hindbrain development GO:0030902 65 32 0,000 0,15538383 0,17872066 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,15538383 0,17863656 ! gene silencing GO:0016458 71 32 0,000 0,15538383 0,17855253 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,15983143 0,18357695 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,15983143 0,18349069 GO:0055092|sterol homeostasis, ! pigment biosynthetic process GO:0046148 73 33 0,000 0,15983143 0,1834045 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,15983143 0,18331839 ! triglyceride metabolic process GO:0006641 46 33 0,000 0,15983143 0,18323237 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,15983143 0,18314642 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,15983143 0,18306056 ! leukocyte chemotaxis GO:0030595 55 33 0,000 0,15983143 0,18297478 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,15983143 0,18288908 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,15983143 0,18280345 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,15983143 0,18271791 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,16425573 0,18768791 ! post-embryonic development GO:0009791 76 34 0,000 0,16425573 0,18760017 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,16425573 0,1875125 ! cholesterol transport GO:0030301 62 34 0,000 0,16425573 0,18742492 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,16425573 0,18733742 ! spliceosome assembly GO:0000245 75 34 0,000 0,16425573 0,18725 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,16425573 0,18716267 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,16425573 0,18707541 ! formation of primary germ layer GO:0001704 76 34 0,000 0,16425573 0,18698824 ! cell fate specification GO:0001708 56 34 0,000 0,16425573 0,18690114 ! negative regulation of MAP kinase activity GO:0043407 78 34 0,000 0,16425573 0,18681413 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,16425573 0,1867272 ! adult locomotory behavior GO:0008344 62 34 0,000 0,16425573 0,18664035 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 0,000 0,16425573 0,18655358 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,16865686 0,19146316 ! negative regulation of secretion GO:0051048 68 35 0,000 0,16865686 0,19137423 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,16865686 0,19128539 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,16865686 0,19119662 ! membrane docking GO:0022406 69 35 0,000 0,16865686 0,19110794 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,16865686 0,19101934 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,16865686 0,19093083 ! regulation of striated muscle tissue development GO:0016202 81 35 0,000 0,16865686 0,19084239 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,16865686 0,19075404 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,16865686 0,19066577 ! ceramide metabolic process GO:0006672 72 35 0,000 0,16865686 0,19057758 ! telencephalon development GO:0021537 81 35 0,000 0,16865686 0,19048947 ! sterol transport GO:0015918 63 35 0,000 0,16865686 0,19040144 ! calcium-mediated signaling GO:0019722 67 35 0,000 0,16865686 0,1903135 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,16865686 0,19022563 ! placenta development GO:0001890 53 35 0,000 0,16865686 0,19013785 ! vesicle localization GO:0051648 70 35 0,000 0,16865686 0,19005015 ! regulation of muscle development GO:0048634 82 36 0,000 0,17303494 0,19489367 ! mitotic sister chromatid segregation GO:0000070 63 36 0,000 0,17303494 0,19480385 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,17303494 0,19471412 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,17303494 0,19462448 ! negative regulation of DNA binding GO:0043392 67 36 0,000 0,17303494 0,19453491 ! positive regulation of cell development GO:0010720 85 36 0,000 0,17303494 0,19444543 ! protein targeting to membrane GO:0006612 75 36 0,000 0,17303494 0,19435603 ! aerobic respiration GO:0009060 56 36 0,000 0,17303494 0,19426671 ! cytokine production GO:0001816 68 36 0,000 0,17303494 0,19417748 ! embryonic organ development GO:0048568 67 36 0,000 0,17303494 0,19408832 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,17303494 0,19399925 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 0,000 0,17739009 0,19879082 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! regulation of smooth muscle cell proliferation GO:0048660 64 37 0,000 0,17739009 0,19869967 ! negative regulation of cell adhesion GO:0007162 94 37 0,000 0,17739009 0,19860861 ! sister chromatid segregation GO:0000819 65 37 0,000 0,17739009 0,19851763 ! odontogenesis GO:0042476 74 37 0,000 0,17739009 0,19842673 ! cell junction organization GO:0034330 96 37 0,000 0,17739009 0,19833592 ! tissue remodeling GO:0048771 78 37 0,000 0,17739009 0,19824519 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,17739009 0,19815454 ! androgen receptor signaling pathway GO:0030521 81 37 0,000 0,17739009 0,19806398 ! regulation of microtubule-based process GO:0032886 86 37 0,000 0,17739009 0,1979735 ! meiosis I GO:0007127 74 38 0,000 0,18172242 0,20271592 ! organic anion transport GO:0015711 82 38 0,000 0,18172242 0,2026234 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,18172242 0,20253096 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,18172242 0,20243861 ! neutral lipid metabolic process GO:0006638 54 38 0,000 0,18172242 0,20234634 GO:0006639|acylglycerol metabolic process, ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,18172242 0,20225415 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,18172242 0,20216205 ! regulation of protein stability GO:0031647 77 38 0,000 0,18172242 0,20207003 ! spermatid development GO:0007286 69 38 0,000 0,18172242 0,2019781 ! glycogen metabolic process GO:0005977 63 38 0,000 0,18172242 0,20188625 ! pigment metabolic process GO:0042440 87 38 0,000 0,18172242 0,20179448 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,18603205 0,20648628 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,18603205 0,20639251 ! negative regulation of binding GO:0051100 71 39 0,000 0,18603205 0,20629882 ! carbohydrate homeostasis GO:0033500 59 39 0,000 0,18603205 0,20620522 GO:0042593|glucose homeostasis, ! erythrocyte homeostasis GO:0034101 75 39 0,000 0,18603205 0,2061117 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,18603205 0,20601827 ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,18603205 0,20592492 ! glucan metabolic process GO:0044042 64 39 0,000 0,18603205 0,20583166 GO:0006073|cellular glucan metabolic process, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,19031911 0,21047967 GO:0006956|complement activation, ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,19031911 0,21038443 ! lipid homeostasis GO:0055088 75 40 0,000 0,19031911 0,21028928 ! mismatch repair GO:0006298 58 40 0,000 0,19031911 0,21019421 ! glycerol ether metabolic process GO:0006662 57 40 0,000 0,19031911 0,21009923 ! RNA export from nucleus GO:0006405 61 41 0,000 0,19458371 0,21471003 ! mRNA catabolic process GO:0006402 79 41 0,000 0,19458371 0,21461309 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,19458371 0,21451625 ! regulation of hormone secretion GO:0046883 69 41 0,000 0,19458371 0,21441949 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,19458371 0,21432282 ! feeding behavior GO:0007631 69 41 0,000 0,19458371 0,21422623 ! spermatid differentiation GO:0048515 73 41 0,000 0,19458371 0,21412973 ! RNA modification GO:0009451 64 41 0,000 0,19458371 0,21403332 ! organic ether metabolic process GO:0018904 59 42 0,000 0,19882597 0,21860119 ! regulation of protein secretion GO:0050708 77 42 0,000 0,19882597 0,21850285 ! dorsal/ventral pattern formation GO:0009953 75 42 0,000 0,19882597 0,2184046 ! positive regulation of transcription factor activity GO:0051091 71 43 0,000 0,203046 0,22293994 GO:0090047|positive regulation of transcription regulator activity, ! epithelial cell differentiation GO:0030855 83 43 0,000 0,203046 0,22283979 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,203046 0,22273973 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,203046 0,22263975 ! regulation of tube size GO:0035150 76 43 0,000 0,203046 0,22253987 GO:0050880|regulation of blood vessel size, ! glucose transport GO:0015758 66 43 0,000 0,203046 0,22244008 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,203046 0,22234037 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,203046 0,22224076 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,203046 0,22214123 ! segmentation GO:0035282 78 43 0,000 0,203046 0,2220418 ! neuron migration GO:0001764 85 43 0,000 0,203046 0,22194245 ! regulation of myeloid cell differentiation GO:0045637 105 43 0,000 0,203046 0,22184319 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,20724392 0,22632852 ! energy reserve metabolic process GO:0006112 76 44 0,000 0,20724392 0,22622739 ! negative regulation of protein complex disassembly GO:0043242 113 44 0,000 0,20724392 0,22612635 ! positive regulation of response to external stimulus GO:0032103 88 44 0,000 0,20724392 0,2260254 ! hexose transport GO:0008645 68 44 0,000 0,20724392 0,22592454 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 0,000 0,20724392 0,22582377 ! phagocytosis GO:0006909 105 44 0,000 0,20724392 0,22572309 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,20724392 0,2256225 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,21141985 0,23006623 ! branching morphogenesis of a tube GO:0048754 102 45 0,000 0,21141985 0,22996379 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,21141985 0,22986145 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,21141985 0,2297592 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,21557389 0,23416942 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,21557389 0,23406534 ! glycolysis GO:0006096 71 46 0,000 0,21557389 0,23396136 ! leukocyte migration GO:0050900 75 46 0,000 0,21557389 0,23385747 ! negative regulation of cell migration GO:0030336 122 46 0,000 0,21557389 0,23375367 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,21557389 0,23364996 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,21557389 0,23354635 ! cell growth GO:0016049 90 46 0,000 0,21557389 0,23344283 ! positive regulation of protein transport GO:0051222 80 46 0,000 0,21557389 0,2333394 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,21970617 0,2377069 ! positive regulation of defense response GO:0031349 88 48 0,000 0,2238168 0,24204712 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,2238168 0,24194002 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 0,000 0,2238168 0,24183301 ! endosome transport GO:0016197 127 48 0,000 0,2238168 0,2417261 ! positive regulation of DNA binding GO:0043388 83 48 0,000 0,2238168 0,24161928 ! vascular process in circulatory system GO:0003018 85 48 0,000 0,2238168 0,24151256 ! male sex differentiation GO:0046661 93 48 0,000 0,2238168 0,24140593 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,2238168 0,2412994 ! regulation of inflammatory response GO:0050727 84 48 0,000 0,2238168 0,24119296 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,22790589 0,24549122 ! JNK cascade GO:0007254 106 49 0,000 0,22790589 0,24538302 ! protein homooligomerization GO:0051260 84 49 0,000 0,22790589 0,24527493 ! regulation of ion transport GO:0043269 86 50 0,000 0,23197355 0,24954266 ! induction of apoptosis by extracellular signals GO:0008624 99 50 0,000 0,23197355 0,24943282 ! endocrine system development GO:0035270 109 50 0,000 0,23197355 0,24932309 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,23197355 0,24921345 ! regulation of ossification GO:0030278 123 50 0,000 0,23197355 0,2491039 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,23197355 0,24899445 GO:0019724|B cell mediated immunity, ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,23197355 0,2488851 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,23197355 0,24877585 ! regulation of cell projection organization GO:0031344 135 51 0,000 0,23601989 0,25300421 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,23601989 0,25289324 ! peptide metabolic process GO:0006518 80 51 0,000 0,23601989 0,25278237 ! positive regulation of binding GO:0051099 88 52 0,000 0,24004503 0,25698072 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,24004503 0,25686816 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,24004503 0,2567557 ! excretion GO:0007588 87 52 0,000 0,24004503 0,25664333 ! histone modification GO:0016570 104 52 0,000 0,24004503 0,25653106 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,24004503 0,25641889 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,24004503 0,25630682 ! morphogenesis of a branching structure GO:0001763 116 52 0,000 0,24004503 0,25619485 ! amino acid activation GO:0043038 98 52 0,000 0,24004503 0,25608297 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,24404908 0,2602409 ! inner ear development GO:0048839 89 53 0,000 0,24404908 0,26012735 ! chromatin remodeling GO:0006338 122 53 0,000 0,24404908 0,26001391 ! cartilage development GO:0051216 99 53 0,000 0,24404908 0,25990056 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,24803214 0,26402724 ! activation of phospholipase C activity GO:0007202 110 54 0,000 0,24803214 0,26391224 GO:0010863|positive regulation of phospholipase C activity, ! neuromuscular process GO:0050905 107 54 0,000 0,24803214 0,26379735 ! embryonic skeletal system development GO:0048706 101 54 0,000 0,24803214 0,26368256 ! regulation of muscle contraction GO:0006937 94 54 0,000 0,24803214 0,26356786 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,24803214 0,26345327 ! covalent chromatin modification GO:0016569 115 54 0,000 0,24803214 0,26333877 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,24803214 0,26322438 ! RNA catabolic process GO:0006401 103 55 0,000 0,25199432 0,26731313 ! positive regulation of phospholipase activity GO:0010518 111 55 0,000 0,25199432 0,26719711 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,25199432 0,26708119 ! cell recognition GO:0008037 98 55 0,000 0,25199432 0,26696537 ! regulation of protein polymerization GO:0032271 117 55 0,000 0,25199432 0,26684965 ! negative regulation of cell motion GO:0051271 142 55 0,000 0,25199432 0,26673403 ! negative regulation of cytoskeleton organization GO:0051494 139 56 0,000 0,25593574 0,27078866 ! glucose catabolic process GO:0006007 88 56 0,000 0,25593574 0,27067144 ! RNA elongation GO:0006354 90 56 0,000 0,25593574 0,27055432 ! chloride transport GO:0006821 102 57 0,000 0,25985651 0,27458021 ! regulation of bone remodeling GO:0046850 143 57 0,000 0,25985651 0,2744615 ! regulation of phospholipase activity GO:0010517 113 57 0,000 0,25985651 0,27434289 ! heart morphogenesis GO:0003007 105 57 0,000 0,25985651 0,27422438 ! cellular polysaccharide metabolic process GO:0044264 93 58 0,000 0,26375672 0,27822006 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,26375672 0,27809998 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,26375672 0,27798001 ! gastrulation GO:0007369 122 58 0,000 0,26375672 0,27786014 ! regulation of tissue remodeling GO:0034103 146 58 0,000 0,26375672 0,27774037 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,26375672 0,27762071 ! positive regulation of lipase activity GO:0060193 115 58 0,000 0,26375672 0,27750115 ! establishment of organelle localization GO:0051656 122 59 0,000 0,26763649 0,28146188 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,27149592 0,28539782 ! lipid modification GO:0030258 112 60 0,000 0,27149592 0,28527507 ! regulation of endocytosis GO:0030100 104 60 0,000 0,27149592 0,28515242 ! adult behavior GO:0030534 104 60 0,000 0,27149592 0,28502988 ! kidney development GO:0001822 133 60 0,000 0,27149592 0,28490745 ! positive regulation of secretion GO:0051047 110 61 0,000 0,27533512 0,28881224 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,27533512 0,28868829 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,27533512 0,28856444 ! cytokine-mediated signaling pathway GO:0019221 112 61 0,000 0,27533512 0,2884407 ! regulation of heart contraction GO:0008016 123 61 0,000 0,27533512 0,28831706 ! camera-type eye development GO:0043010 126 61 0,000 0,27533512 0,28819353 ! tRNA processing GO:0008033 102 62 0,000 0,2791542 0,29206583 ! regulation of protein complex assembly GO:0043254 132 63 0,000 0,28295326 0,29591388 ! regulation of mitosis GO:0007088 112 63 0,000 0,28295326 0,29578725 GO:0051783|regulation of nuclear division, ! mesoderm development GO:0007498 128 63 0,000 0,28295326 0,29566074 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,28295326 0,29553434 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,2867324 0,29935353 ! integrin-mediated signaling pathway GO:0007229 160 64 0,000 0,2867324 0,29922565 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,29049173 0,30301934 ! lymphocyte mediated immunity GO:0002449 122 65 0,000 0,29049173 0,30289001 ! multicellular organism reproduction GO:0032504 123 65 0,000 0,29049173 0,30276079 GO:0048609|reproductive process in a multicellular organism, ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,29049173 0,30263168 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,29049173 0,30250269 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,29423135 0,30626638 ! steroid hormone receptor signaling pathway GO:0030518 146 66 0,000 0,29423135 0,30613594 ! embryonic limb morphogenesis GO:0030326 139 67 0,000 0,29795137 0,3098745 GO:0035113|embryonic appendage morphogenesis, ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,29795137 0,30974264 ! secondary metabolic process GO:0019748 125 67 0,000 0,29795137 0,30961089 ! myeloid cell differentiation GO:0030099 126 67 0,000 0,29795137 0,30947925 ! regulation of cellular response to stress GO:0080135 142 68 0,000 0,30165188 0,31318978 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,30165188 0,31305673 ! hexose catabolic process GO:0019320 113 68 0,000 0,30165188 0,3129238 ! extracellular matrix organization GO:0030198 146 68 0,000 0,30165188 0,31279098 ! regulation of lipase activity GO:0060191 137 68 0,000 0,30165188 0,31265827 ! adaptive immune response GO:0002250 126 68 0,000 0,30165188 0,31252568 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! cell projection assembly GO:0030031 138 68 0,000 0,30165188 0,3123932 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,30533299 0,3160714 ! lung development GO:0030324 165 69 0,000 0,30533299 0,31593753 ! urogenital system development GO:0001655 149 69 0,000 0,30533299 0,31580377 ! homeostasis of number of cells GO:0048872 131 69 0,000 0,30533299 0,31567012 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,30533299 0,31553659 ! single fertilization GO:0007338 83 69 0,000 0,30533299 0,31540317 ! cell redox homeostasis GO:0045454 114 70 0,000 0,3089948 0,31905085 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,31263742 0,32267563 ! cAMP-mediated signaling GO:0019933 124 71 0,000 0,31263742 0,32253936 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 0,000 0,31263742 0,32240321 ! appendage morphogenesis GO:0035107 150 72 0,000 0,31626093 0,3260023 GO:0035108|limb morphogenesis, ! carbohydrate transport GO:0008643 114 72 0,000 0,31626093 0,3258648 ! respiratory tube development GO:0030323 171 72 0,000 0,31626093 0,32572742 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,31626093 0,32559016 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,31626093 0,32545301 ! appendage development GO:0048736 151 73 0,000 0,31986544 0,32902369 GO:0060173|limb development, ! humoral immune response GO:0006959 115 73 0,000 0,31986544 0,32888521 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,31986544 0,32874685 ! acute inflammatory response GO:0002526 118 74 0,000 0,32345105 0,33229222 ! amino acid transport GO:0006865 148 74 0,000 0,32345105 0,33215255 ! respiratory system development GO:0060541 175 74 0,000 0,32345105 0,33201299 ! organelle localization GO:0051640 155 74 0,000 0,32345105 0,33187354 ! regulation of transcription factor activity GO:0051090 137 75 0,000 0,32701785 0,33539237 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 143 75 0,000 0,32701785 0,33525162 ! leukocyte mediated immunity GO:0002443 136 75 0,000 0,32701785 0,335111 ! eye development GO:0001654 155 75 0,000 0,32701785 0,33497049 ! rhythmic process GO:0048511 142 75 0,000 0,32701785 0,3348301 ! cell-matrix adhesion GO:0007160 181 76 0,000 0,33056596 0,33832117 ! regulation of blood pressure GO:0008217 134 76 0,000 0,33056596 0,33817949 ! amine catabolic process GO:0009310 136 77 0,000 0,33409545 0,34164721 ! neurotransmitter transport GO:0006836 142 77 0,000 0,33409545 0,34150426 ! phosphoinositide metabolic process GO:0030384 146 77 0,000 0,33409545 0,34136144 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,33409545 0,34121873 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,33409545 0,34107614 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,33760644 0,34451651 ! antigen processing and presentation GO:0019882 117 78 0,000 0,33760644 0,34437266 ! fertilization GO:0009566 99 78 0,000 0,33760644 0,34422894 ! steroid biosynthetic process GO:0006694 146 79 0,000 0,34109901 0,34764493 ! regulation of synaptic transmission GO:0050804 159 79 0,000 0,34109901 0,34749995 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 0,000 0,34457327 0,35089308 ! negative regulation of organelle organization GO:0010639 181 80 0,000 0,34457327 0,35074687 ! response to hypoxia GO:0001666 178 81 0,000 0,3480293 0,35411728 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 0,000 0,3480293 0,35396985 ! cell-substrate adhesion GO:0031589 189 82 0,000 0,35146721 0,35731768 ! regulation of adenylate cyclase activity GO:0045761 165 83 0,000 0,35488709 0,36064441 ! exocytosis GO:0006887 153 83 0,000 0,35488709 0,36049445 ! response to oxygen levels GO:0070482 183 83 0,000 0,35488709 0,36034462 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,35488709 0,36019491 ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,35488709 0,36004533 ! inorganic anion transport GO:0015698 156 83 0,000 0,35488709 0,35989587 ! digestion GO:0007586 130 84 0,000 0,35828902 0,36319506 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,36167312 0,36647342 ! regulation of cyclase activity GO:0031279 168 85 0,000 0,36167312 0,36632149 ! regulation of transmission of nerve impulse GO:0051969 167 85 0,000 0,36167312 0,36616967 ! regulation of cAMP biosynthetic process GO:0030817 173 86 0,000 0,36503946 0,36942477 ! regulation of lyase activity GO:0051339 169 86 0,000 0,36503946 0,3692718 ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,36838814 0,37250506 ! nucleosome assembly GO:0006334 126 87 0,000 0,36838814 0,37235094 ! cellular respiration GO:0045333 143 88 0,000 0,37171926 0,37556251 ! amine biosynthetic process GO:0009309 146 88 0,000 0,37171926 0,37540726 ! sensory perception of smell GO:0007608 117 88 0,000 0,37171926 0,37525213 ! chromatin assembly GO:0031497 128 88 0,000 0,37171926 0,37509713 ! regulation of cAMP metabolic process GO:0030814 182 89 0,000 0,3750329 0,37828463 ! regulation of DNA binding GO:0051101 167 89 0,000 0,3750329 0,37812851 ! cellular defense response GO:0006968 123 89 0,000 0,3750329 0,37797252 ! regulation of neurological system process GO:0031644 175 89 0,000 0,3750329 0,37781665 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 0,000 0,38160813 0,38428221 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! defense response to bacterium GO:0042742 112 91 0,000 0,38160813 0,38412388 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,38486989 0,38724759 ! amine transport GO:0015837 181 93 0,000 0,38811454 0,39035151 ! vitamin metabolic process GO:0006766 153 93 0,000 0,38811454 0,39019087 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,39134217 0,39327392 ! female pregnancy GO:0007565 166 94 0,000 0,39134217 0,39311222 ! sterol metabolic process GO:0016125 166 94 0,000 0,39134217 0,39295064 ! regulation of defense response GO:0031347 171 95 0,000 0,39455286 0,39601176 ! nucleosome organization GO:0034728 143 95 0,000 0,39455286 0,39584913 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,39455286 0,39568663 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 0,000 0,39455286 0,39552426 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,39455286 0,39536203 ! negative regulation of multicellular organismal process GO:0051241 174 95 0,000 0,39455286 0,39519993 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,40092379 0,40141673 ! regulation of nucleotide metabolic process GO:0006140 197 98 0,000 0,4040842 0,40441528 ! mRNA transport GO:0051028 185 100 0,000 0,41035537 0,41052341 ! hormone metabolic process GO:0042445 171 100 0,000 0,41035537 0,41035537