pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6749-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 5,000 7,903E-09 1,902E-05 ! peptidyl-tyrosine modification GO:0018212 50 28 5,000 1,281E-08 1,541E-05 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 3,000 3,981E-08 3,193E-05 ! cellular response to insulin stimulus GO:0032869 82 37 5,000 7,564E-08 4,55E-05 ! positive regulation of inflammatory response GO:0050729 35 21 4,000 1,249E-07 6,011E-05 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 6,000 1,389E-07 5,571E-05 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 6,000 2,296E-07 7,891E-05 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 3,000 2,356E-07 7,085E-05 ! induction of apoptosis by intracellular signals GO:0008629 93 45 5,000 2,549E-07 6,814E-05 ! negative regulation of phosphorylation GO:0042326 47 24 4,000 2,572E-07 6,189E-05 ! response to insulin stimulus GO:0032868 95 46 5,000 2,917E-07 6,38E-05 ! negative regulation of glucose import GO:0046325 17 11 3,000 3,685E-07 7,388E-05 GO:0010829|negative regulation of glucose transport, ! negative regulation of phosphorus metabolic process GO:0010563 51 26 4,000 3,943E-07 7,298E-05 GO:0045936|negative regulation of phosphate metabolic process, ! positive regulation of phosphorylation GO:0042327 129 79 6,000 4,364E-07 7,5E-05 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 6,000 5,184E-07 8,315E-05 GO:0045937|positive regulation of phosphate metabolic process, ! cellular response to hormone stimulus GO:0032870 167 82 6,000 5,64E-07 8,48E-05 ! negative regulation of transport GO:0051051 153 84 6,000 6,653E-07 9,416E-05 ! ribosomal large subunit biogenesis GO:0042273 13 13 3,000 7,911E-07 1,057E-04 ! positive regulation of protein modification process GO:0031401 136 88 6,000 9,143E-07 1,158E-04 ! gland development GO:0048732 206 88 6,000 9,143E-07 1,1E-04 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 3,000 1,102E-06 1,263E-04 ! cytokine-mediated signaling pathway GO:0019221 97 59 5,000 1,317E-06 1,441E-04 ! response to peptide hormone stimulus GO:0043434 122 61 5,000 1,608E-06 1,682E-04 ! regulation of T cell proliferation GO:0042129 71 41 4,000 4,183E-06 4,193E-04 ! regulation of T cell differentiation GO:0045580 70 41 4,000 4,183E-06 4,025E-04 ! apoptotic mitochondrial changes GO:0008637 41 20 3,000 5,191E-06 4,804E-04 ! regulation of glucose import GO:0046324 29 20 3,000 5,191E-06 4,626E-04 GO:0010827|regulation of glucose transport, ! positive regulation of response to external stimulus GO:0032103 77 43 4,000 5,322E-06 4,573E-04 ! positive regulation of locomotion GO:0040017 39 21 3,000 6,383E-06 5,296E-04 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! regulation of chemotaxis GO:0050920 40 22 3,000 7,765E-06 6,228E-04 ! protein import into nucleus GO:0006606 158 80 5,000 7,933E-06 6,157E-04 ! positive regulation of defense response GO:0031349 76 47 4,000 8,321E-06 6,256E-04 ! nuclear import GO:0051170 161 81 5,000 8,526E-06 6,217E-04 ! regulation of inflammatory response GO:0050727 75 48 4,000 9,245E-06 6,542E-04 ! regulation of lymphocyte differentiation GO:0045619 81 48 4,000 9,245E-06 6,355E-04 ! regulation of mast cell proliferation GO:0070666 81 48 4,000 9,245E-06 6,178E-04 ! positive regulation of DNA replication GO:0045740 43 23 3,000 9,357E-06 6,085E-04 ! regulation of fat cell differentiation GO:0045598 15 8 2,000 1,094E-05 6,925E-04 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 2,000 1,094E-05 6,747E-04 ! protein import into nucleus, translocation GO:0000060 46 24 3,000 1,118E-05 6,723E-04 ! regulation of behavior GO:0050795 43 24 3,000 1,118E-05 6,559E-04 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 4,000 1,25E-05 7,162E-04 ! regulation of leukocyte proliferation GO:0070663 88 51 4,000 1,25E-05 6,996E-04 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! protein localization in nucleus GO:0034504 176 87 5,000 1,289E-05 7,047E-04 ! osteoblast differentiation GO:0001649 60 25 3,000 1,325E-05 7,082E-04 ! regulation of DNA binding GO:0051101 155 88 5,000 1,376E-05 7,198E-04 ! insulin receptor signaling pathway GO:0008286 64 26 3,000 1,558E-05 7,977E-04 ! induction of positive chemotaxis GO:0050930 15 9 2,000 1,633E-05 8,188E-04 ! regulation of fibroblast proliferation GO:0048145 52 27 3,000 1,821E-05 8,94E-04 ! regulation of DNA replication GO:0006275 101 56 4,000 1,985E-05 9,554E-04 ! regulation of T cell activation GO:0050863 158 94 5,000 2,008E-05 9,475E-04 ! negative regulation of protein modification process GO:0031400 60 28 3,000 2,115E-05 9,784E-04 ! positive regulation of cell migration GO:0030335 126 57 4,000 2,166E-05 9,833E-04 ! smoothened signaling pathway GO:0007224 16 10 2,000 2,323E-05 1,035E-03 ! regulation of smoothened signaling pathway GO:0008589 23 10 2,000 2,323E-05 1,016E-03 ! regulation of DNA metabolic process GO:0051052 178 97 5,000 2,402E-05 1,032E-03 ! kidney development GO:0001822 122 60 4,000 2,785E-05 1,176E-03 ! chondrocyte differentiation GO:0002062 24 11 2,000 3,181E-05 1,319E-03 ! neuroblast proliferation GO:0007405 24 11 2,000 3,181E-05 1,297E-03 ! regulation of protein import into nucleus GO:0042306 63 32 3,000 3,646E-05 1,462E-03 ! positive regulation of cell motion GO:0051272 146 64 4,000 3,816E-05 1,505E-03 ! leukocyte chemotaxis GO:0030595 50 33 3,000 4,13E-05 1,603E-03 GO:0060326|cell chemotaxis, ! regulation of positive chemotaxis GO:0050926 19 12 2,000 4,223E-05 1,613E-03 GO:0050927|positive regulation of positive chemotaxis, ! mRNA polyadenylation GO:0006378 23 12 2,000 4,223E-05 1,587E-03 ! autonomic nervous system development GO:0048483 24 12 2,000 4,223E-05 1,563E-03 ! negative regulation of mast cell proliferation GO:0070667 23 12 2,000 4,223E-05 1,539E-03 GO:0042130|negative regulation of T cell proliferation, ! odontogenesis GO:0042476 66 35 3,000 5,237E-05 1,88E-03 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 2,000 5,466E-05 1,934E-03 ! mRNA 3'-end processing GO:0031124 24 13 2,000 5,466E-05 1,906E-03 ! cytoplasmic sequestering of protein GO:0051220 24 13 2,000 5,466E-05 1,879E-03 ! cell cycle checkpoint GO:0000075 137 69 4,000 5,492E-05 1,861E-03 ! urogenital system development GO:0001655 137 69 4,000 5,492E-05 1,835E-03 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 3,000 5,864E-05 1,933E-03 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! negative regulation of DNA binding GO:0043392 68 37 3,000 6,545E-05 2,128E-03 ! RNA polyadenylation GO:0043631 30 14 2,000 6,926E-05 2,222E-03 ! actin cytoskeleton reorganization GO:0031532 33 14 2,000 6,926E-05 2,193E-03 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 2,000 6,926E-05 2,164E-03 ! release of cytochrome c from mitochondria GO:0001836 30 14 2,000 6,926E-05 2,137E-03 ! positive regulation of DNA metabolic process GO:0051054 72 38 3,000 7,282E-05 2,218E-03 ! mitotic cell cycle checkpoint GO:0007093 76 38 3,000 7,282E-05 2,19E-03 ! regulation of transcription factor activity GO:0051090 126 74 4,000 7,688E-05 2,284E-03 GO:0090046|regulation of transcription regulator activity, ! mammary gland development GO:0030879 86 39 3,000 8,077E-05 2,37E-03 ! regulation of the force of heart contraction GO:0002026 26 15 2,000 8,621E-05 2,499E-03 ! positive regulation of oxidoreductase activity GO:0051353 22 15 2,000 8,621E-05 2,469E-03 ! regulation of T-helper cell differentiation GO:0045622 26 15 2,000 8,621E-05 2,44E-03 ! negative regulation of binding GO:0051100 72 40 3,000 8,933E-05 2,499E-03 ! dorsal/ventral pattern formation GO:0009953 68 41 3,000 9,854E-05 2,725E-03 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 2,000 1,056E-04 2,888E-03 ! positive regulation of protein import into nucleus GO:0042307 30 16 2,000 1,056E-04 2,856E-03 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 2,000 1,056E-04 2,824E-03 ! negative regulation of leukocyte proliferation GO:0070664 31 16 2,000 1,056E-04 2,793E-03 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 2,000 1,056E-04 2,763E-03 ! regulation of intracellular protein transport GO:0033157 80 42 3,000 1,084E-04 2,805E-03 ! T cell activation GO:0042110 168 81 4,000 1,183E-04 3,028E-03 ! regulation of epithelial cell proliferation GO:0050678 111 43 3,000 1,19E-04 3,013E-03 ! negative regulation of cell cycle process GO:0010948 32 17 2,000 1,277E-04 3,201E-03 ! signal complex assembly GO:0007172 41 17 2,000 1,277E-04 3,168E-03 ! regulation of survival gene product expression GO:0045884 33 17 2,000 1,277E-04 3,136E-03 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 2,000 1,277E-04 3,104E-03 ! neutrophil chemotaxis GO:0030593 27 17 2,000 1,277E-04 3,073E-03 ! RNA 3'-end processing GO:0031123 34 17 2,000 1,277E-04 3,043E-03 ! negative regulation of growth GO:0045926 155 84 4,000 1,405E-04 3,315E-03 ! leukocyte migration GO:0050900 68 45 3,000 1,423E-04 3,325E-03 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 2,000 1,526E-04 3,531E-03 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 2,000 1,526E-04 3,497E-03 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 3,000 1,552E-04 3,522E-03 ! positive regulation of protein transport GO:0051222 72 46 3,000 1,552E-04 3,49E-03 ! regulation of protein transport GO:0051223 154 87 4,000 1,658E-04 3,694E-03 GO:0070201|regulation of establishment of protein localization, ! proximal/distal pattern formation GO:0009954 32 19 2,000 1,804E-04 3,983E-03 ! embryonic organ morphogenesis GO:0048562 26 19 2,000 1,804E-04 3,947E-03 ! activation of caspase activity GO:0006919 84 48 3,000 1,834E-04 3,974E-03 ! ossification GO:0001503 188 90 4,000 1,945E-04 4,178E-03 ! endocrine system development GO:0035270 104 49 3,000 1,987E-04 4,232E-03 ! bone development GO:0060348 189 91 4,000 2,048E-04 4,323E-03 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 2,000 2,114E-04 4,422E-03 ! regulation of carbohydrate metabolic process GO:0006109 38 20 2,000 2,114E-04 4,384E-03 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 2,000 2,114E-04 4,347E-03 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 2,000 2,114E-04 4,31E-03 ! negative regulation of T cell activation GO:0050868 40 20 2,000 2,114E-04 4,274E-03 ! regulation of defense response GO:0031347 149 92 4,000 2,156E-04 4,322E-03 ! positive regulation of MAP kinase activity GO:0043406 160 93 4,000 2,267E-04 4,508E-03 ! epithelial tube morphogenesis GO:0060562 98 51 3,000 2,323E-04 4,581E-03 ! inactivation of MAPK activity GO:0000188 39 21 2,000 2,455E-04 4,803E-03 ! cell structure disassembly during apoptosis GO:0006921 30 21 2,000 2,455E-04 4,764E-03 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 2,000 2,455E-04 4,726E-03 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 2,000 2,455E-04 4,689E-03 ! gut development GO:0048565 39 21 2,000 2,455E-04 4,652E-03 ! regulation of protein localization GO:0032880 176 97 4,000 2,759E-04 5,186E-03 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 2,000 2,831E-04 5,28E-03 ! apoptotic nuclear changes GO:0030262 32 22 2,000 2,831E-04 5,239E-03 ! ureteric bud development GO:0001657 43 22 2,000 2,831E-04 5,199E-03 ! positive regulation of intracellular transport GO:0032388 37 22 2,000 2,831E-04 5,16E-03 ! response to glucocorticoid stimulus GO:0051384 38 22 2,000 2,831E-04 5,121E-03 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 2,000 2,831E-04 5,083E-03 ! positive regulation of caspase activity GO:0043280 95 55 3,000 3,113E-04 5,548E-03 GO:0010952|positive regulation of peptidase activity, ! response to molecule of bacterial origin GO:0002237 34 23 2,000 3,241E-04 5,734E-03 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 1,000 3,395E-04 5,962E-03 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! regulation of collagen biosynthetic process GO:0032965 6 5 1,000 3,395E-04 5,919E-03 ! 2-oxoglutarate metabolic process GO:0006103 7 5 1,000 3,395E-04 5,876E-03 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 1,000 3,395E-04 5,834E-03 ! response to protozoan GO:0001562 10 5 1,000 3,395E-04 5,793E-03 ! positive regulation of glycolysis GO:0045821 14 5 1,000 3,395E-04 5,752E-03 ! parathyroid gland development GO:0060017 13 5 1,000 3,395E-04 5,712E-03 ! epithelial cell proliferation GO:0050673 9 5 1,000 3,395E-04 5,672E-03 ! negative regulation of survival gene product expression GO:0008634 8 5 1,000 3,395E-04 5,633E-03 ! neutrophil mediated immunity GO:0002446 7 5 1,000 3,395E-04 5,595E-03 ! valine metabolic process GO:0006573 10 5 1,000 3,395E-04 5,556E-03 ! positive regulation of filopodium assembly GO:0051491 14 5 1,000 3,395E-04 5,519E-03 GO:0051489|regulation of filopodium assembly, ! regulation of glycogen metabolic process GO:0070873 11 5 1,000 3,395E-04 5,482E-03 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 1,000 3,395E-04 5,445E-03 ! paraxial mesoderm development GO:0048339 14 5 1,000 3,395E-04 5,409E-03 ! early endosome to late endosome transport GO:0045022 12 5 1,000 3,395E-04 5,374E-03 ! meiotic chromosome segregation GO:0045132 7 5 1,000 3,395E-04 5,339E-03 ! positive regulation of chemokine production GO:0032722 8 5 1,000 3,395E-04 5,304E-03 ! enteric nervous system development GO:0048484 8 5 1,000 3,395E-04 5,27E-03 ! receptor biosynthetic process GO:0032800 7 5 1,000 3,395E-04 5,236E-03 ! stem cell division GO:0017145 11 5 1,000 3,395E-04 5,203E-03 GO:0048103|somatic stem cell division, ! cellular anion homeostasis GO:0030002 9 5 1,000 3,395E-04 5,17E-03 GO:0055081|anion homeostasis, ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 3,000 3,572E-04 5,406E-03 ! regulation of intracellular transport GO:0032386 101 57 3,000 3,572E-04 5,372E-03 ! maintenance of location GO:0051235 118 57 3,000 3,572E-04 5,339E-03 ! positive regulation of fibroblast proliferation GO:0048146 43 24 2,000 3,688E-04 5,478E-03 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 2,000 3,688E-04 5,444E-03 ! regulation of alpha-beta T cell activation GO:0046634 42 24 2,000 3,688E-04 5,411E-03 ! regulation of oxidoreductase activity GO:0051341 46 24 2,000 3,688E-04 5,378E-03 ! protein tetramerization GO:0051262 52 24 2,000 3,688E-04 5,346E-03 ! response to corticosteroid stimulus GO:0031960 41 24 2,000 3,688E-04 5,314E-03 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 2,000 4,173E-04 5,977E-03 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 2,000 4,173E-04 5,941E-03 ! receptor metabolic process GO:0043112 46 25 2,000 4,173E-04 5,906E-03 ! negative regulation of cell development GO:0010721 73 25 2,000 4,173E-04 5,872E-03 GO:0050768|negative regulation of neurogenesis, ! protein amino acid autophosphorylation GO:0046777 141 60 3,000 4,35E-04 6,085E-03 ! negative regulation of response to stimulus GO:0048585 100 60 3,000 4,35E-04 6,05E-03 ! regulation of transcription factor import into nucleus GO:0042990 54 26 2,000 4,697E-04 6,495E-03 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 2,000 4,697E-04 6,458E-03 ! positive regulation of actin filament polymerization GO:0030838 11 6 1,000 5,073E-04 6,934E-03 ! forebrain regionalization GO:0021871 8 6 1,000 5,073E-04 6,895E-03 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 1,000 5,073E-04 6,857E-03 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 1,000 5,073E-04 6,818E-03 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 1,000 5,073E-04 6,78E-03 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! cGMP-mediated signaling GO:0019934 13 6 1,000 5,073E-04 6,743E-03 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 1,000 5,073E-04 6,706E-03 GO:0033135|regulation of peptidyl-serine phosphorylation, ! positive regulation of muscle hypertrophy GO:0014742 10 6 1,000 5,073E-04 6,669E-03 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! male sex determination GO:0030238 15 6 1,000 5,073E-04 6,633E-03 ! regulation of immunoglobulin secretion GO:0051023 6 6 1,000 5,073E-04 6,597E-03 ! regulation of collagen metabolic process GO:0010712 9 6 1,000 5,073E-04 6,562E-03 ! establishment of spindle localization GO:0051293 12 6 1,000 5,073E-04 6,527E-03 GO:0051653|spindle localization, ! negative regulation of gliogenesis GO:0014014 18 6 1,000 5,073E-04 6,492E-03 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 1,000 5,073E-04 6,457E-03 ! response to exogenous dsRNA GO:0043330 10 6 1,000 5,073E-04 6,424E-03 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 1,000 5,073E-04 6,39E-03 ! negative regulation of multicellular organism growth GO:0040015 8 6 1,000 5,073E-04 6,357E-03 ! neutrophil homeostasis GO:0001780 10 6 1,000 5,073E-04 6,324E-03 ! salivary gland morphogenesis GO:0007435 13 6 1,000 5,073E-04 6,291E-03 ! negative regulation of neuroblast proliferation GO:0007406 21 6 1,000 5,073E-04 6,259E-03 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 1,000 5,073E-04 6,227E-03 GO:0045625|regulation of T-helper 1 cell differentiation, ! ectodermal gut morphogenesis GO:0048567 12 6 1,000 5,073E-04 6,195E-03 GO:0007439|ectodermal gut development, ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 1,000 5,073E-04 6,164E-03 ! organ or tissue specific immune response GO:0002251 7 6 1,000 5,073E-04 6,133E-03 ! negative regulation of B cell activation GO:0050869 13 6 1,000 5,073E-04 6,102E-03 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 2,000 5,262E-04 6,298E-03 ! regulation of chromosome organization GO:0033044 42 27 2,000 5,262E-04 6,267E-03 ! negative regulation of lymphocyte activation GO:0051250 53 27 2,000 5,262E-04 6,236E-03 ! positive regulation of T cell differentiation GO:0045582 42 28 2,000 5,868E-04 6,921E-03 ! regulation of cytokine biosynthetic process GO:0042035 95 65 3,000 5,903E-04 6,929E-03 ! extracellular matrix organization GO:0030198 133 66 3,000 6,256E-04 7,307E-03 ! actin filament organization GO:0007015 148 66 3,000 6,256E-04 7,271E-03 ! negative regulation of protein kinase activity GO:0006469 130 67 3,000 6,623E-04 7,661E-03 ! negative regulation of cell growth GO:0030308 132 67 3,000 6,623E-04 7,624E-03 ! lung development GO:0030324 144 67 3,000 6,623E-04 7,588E-03 ! positive regulation of T cell activation GO:0050870 109 67 3,000 6,623E-04 7,552E-03 ! negative regulation of kinase activity GO:0033673 131 68 3,000 7,005E-04 7,95E-03 ! regulation of helicase activity GO:0051095 15 7 1,000 7,074E-04 7,991E-03 ! cytokinesis during cell cycle GO:0033205 11 7 1,000 7,074E-04 7,953E-03 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 1,000 7,074E-04 7,916E-03 ! Golgi to plasma membrane transport GO:0006893 14 7 1,000 7,074E-04 7,88E-03 ! neuron adhesion GO:0007158 12 7 1,000 7,074E-04 7,844E-03 ! oxaloacetate metabolic process GO:0006107 10 7 1,000 7,074E-04 7,808E-03 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 1,000 7,074E-04 7,772E-03 ! lipoprotein transport GO:0042953 14 7 1,000 7,074E-04 7,737E-03 ! spinal cord patterning GO:0021511 13 7 1,000 7,074E-04 7,702E-03 ! regulation of granule cell precursor proliferation GO:0021936 13 7 1,000 7,074E-04 7,667E-03 GO:0021940|positive regulation of granule cell precursor proliferation, ! spindle checkpoint GO:0031577 15 7 1,000 7,074E-04 7,632E-03 ! G1 DNA damage checkpoint GO:0031571 21 7 1,000 7,074E-04 7,598E-03 ! B cell lineage commitment GO:0002326 21 7 1,000 7,074E-04 7,565E-03 ! cranial nerve morphogenesis GO:0021602 11 7 1,000 7,074E-04 7,531E-03 ! T cell lineage commitment GO:0002360 16 7 1,000 7,074E-04 7,498E-03 ! response to tumor cell GO:0002347 13 7 1,000 7,074E-04 7,465E-03 ! regulation of respiratory burst GO:0060263 11 7 1,000 7,074E-04 7,433E-03 ! axonal fasciculation GO:0007413 18 7 1,000 7,074E-04 7,4E-03 ! negative regulation of nuclear division GO:0051784 14 7 1,000 7,074E-04 7,368E-03 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 1,000 7,074E-04 7,336E-03 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 1,000 7,074E-04 7,305E-03 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 1,000 7,074E-04 7,274E-03 ! muscle adaptation GO:0043500 14 7 1,000 7,074E-04 7,243E-03 ! defense response to Gram-negative bacterium GO:0050829 9 7 1,000 7,074E-04 7,212E-03 ! negative regulation of leukocyte activation GO:0002695 56 30 2,000 7,21E-04 7,319E-03 ! regulation of B cell activation GO:0050864 50 30 2,000 7,21E-04 7,288E-03 ! negative regulation of cell size GO:0045792 134 69 3,000 7,402E-04 7,451E-03 ! respiratory tube development GO:0030323 150 70 3,000 7,815E-04 7,834E-03 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 2,000 7,948E-04 7,934E-03 ! positive regulation of T cell proliferation GO:0042102 52 31 2,000 7,948E-04 7,902E-03 ! negative regulation of transcription regulator activity GO:0090048 58 31 2,000 7,948E-04 7,869E-03 GO:0043433|negative regulation of transcription factor activity, ! regulation of caspase activity GO:0043281 122 72 3,000 8,689E-04 8,568E-03 ! negative regulation of transferase activity GO:0051348 140 72 3,000 8,689E-04 8,533E-03 ! respiratory system development GO:0060541 153 72 3,000 8,689E-04 8,498E-03 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 2,000 8,732E-04 8,506E-03 ! spindle organization GO:0007051 46 32 2,000 8,732E-04 8,472E-03 ! metanephros development GO:0001656 74 32 2,000 8,732E-04 8,438E-03 ! negative regulation of MAP kinase activity GO:0043407 69 32 2,000 8,732E-04 8,404E-03 ! peripheral nervous system development GO:0007422 64 32 2,000 8,732E-04 8,37E-03 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 2,000 8,732E-04 8,337E-03 ! regulation of blood pressure GO:0008217 125 73 3,000 9,151E-04 8,702E-03 ! axon guidance GO:0007411 139 73 3,000 9,151E-04 8,668E-03 ! succinate metabolic process GO:0006105 14 8 1,000 9,396E-04 8,865E-03 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 1,000 9,396E-04 8,831E-03 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 9,396E-04 8,796E-03 ! L-phenylalanine metabolic process GO:0006558 11 8 1,000 9,396E-04 8,762E-03 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 12 8 1,000 9,396E-04 8,728E-03 ! positive regulation of endothelial cell migration GO:0010595 19 8 1,000 9,396E-04 8,695E-03 ! regulation of muscle hypertrophy GO:0014743 12 8 1,000 9,396E-04 8,661E-03 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 1,000 9,396E-04 8,628E-03 ! cerebral cortex neuron differentiation GO:0021895 16 8 1,000 9,396E-04 8,596E-03 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 1,000 9,396E-04 8,563E-03 ! negative regulation of translational initiation GO:0045947 10 8 1,000 9,396E-04 8,531E-03 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 1,000 9,396E-04 8,499E-03 ! regulation of T-helper 1 type immune response GO:0002825 9 8 1,000 9,396E-04 8,467E-03 ! myeloid cell homeostasis GO:0002262 13 8 1,000 9,396E-04 8,435E-03 ! negative regulation of protein transport GO:0051224 69 33 2,000 9,564E-04 8,554E-03 ! regulation of endopeptidase activity GO:0052548 125 74 3,000 9,63E-04 8,581E-03 ! phosphoinositide-mediated signaling GO:0048015 131 75 3,000 1,013E-03 8,99E-03 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 2,000 1,044E-03 9,239E-03 ! positive regulation of lymphocyte activation GO:0051251 127 77 3,000 1,117E-03 9,846E-03 ! telencephalon development GO:0021537 68 35 2,000 1,137E-03 9,988E-03 ! protein oligomerization GO:0051259 139 78 3,000 1,172E-03 0,0102565 ! regulation of developmental growth GO:0048638 15 9 1,000 1,203E-03 0,01049016 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 1,203E-03 0,01045229 ! regulation of glycolysis GO:0006110 21 9 1,000 1,203E-03 0,01041469 ! keratinocyte proliferation GO:0043616 14 9 1,000 1,203E-03 0,01037736 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 1,000 1,203E-03 0,0103403 ! middle ear morphogenesis GO:0042474 14 9 1,000 1,203E-03 0,0103035 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 1,000 1,203E-03 0,01026697 ! phosphagen metabolic process GO:0006599 12 9 1,000 1,203E-03 0,01023069 GO:0006600|creatine metabolic process, ! receptor clustering GO:0043113 18 9 1,000 1,203E-03 0,01019466 ! regulation of Notch signaling pathway GO:0008593 22 9 1,000 1,203E-03 0,01015889 ! motor axon guidance GO:0008045 16 9 1,000 1,203E-03 0,01012337 ! protein heterooligomerization GO:0051291 16 9 1,000 1,203E-03 0,0100881 ! alpha-beta T cell differentiation GO:0046632 21 9 1,000 1,203E-03 0,01005307 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 1,000 1,203E-03 0,01001829 ! spinal cord motor neuron differentiation GO:0021522 15 9 1,000 1,203E-03 9,984E-03 ! cerebellum morphogenesis GO:0021587 14 9 1,000 1,203E-03 9,949E-03 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 1,000 1,203E-03 9,915E-03 ! S phase GO:0051320 9 9 1,000 1,203E-03 9,882E-03 GO:0000084|S phase of mitotic cell cycle, ! regulation of telomere maintenance GO:0032204 14 9 1,000 1,203E-03 9,848E-03 ! regulation of muscle adaptation GO:0043502 14 9 1,000 1,203E-03 9,815E-03 ! regulation of peptidase activity GO:0052547 134 79 3,000 1,229E-03 9,992E-03 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 3,000 1,229E-03 9,958E-03 ! positive regulation of JAK-STAT cascade GO:0046427 50 36 2,000 1,236E-03 9,975E-03 ! maintenance of protein location in cell GO:0032507 86 36 2,000 1,236E-03 9,942E-03 ! embryonic organ development GO:0048568 57 36 2,000 1,236E-03 9,909E-03 ! negative regulation of cell activation GO:0050866 65 36 2,000 1,236E-03 9,876E-03 ! regulation of adenylate cyclase activity GO:0045761 156 80 3,000 1,288E-03 0,01026165 ! meiosis I GO:0007127 65 37 2,000 1,339E-03 0,01063068 ! tissue remodeling GO:0048771 76 37 2,000 1,339E-03 0,01059572 ! regulation of protein stability GO:0031647 73 37 2,000 1,339E-03 0,01056098 ! regulation of cAMP biosynthetic process GO:0030817 161 82 3,000 1,412E-03 0,0110986 ! regulation of cyclase activity GO:0031279 159 82 3,000 1,412E-03 0,01106245 ! carbohydrate homeostasis GO:0033500 53 38 2,000 1,447E-03 0,01130576 GO:0042593|glucose homeostasis, ! nucleus organization GO:0006997 67 38 2,000 1,447E-03 0,01126917 ! embryonic epithelial tube formation GO:0001838 72 38 2,000 1,447E-03 0,01123282 ! positive regulation of leukocyte proliferation GO:0070665 62 38 2,000 1,447E-03 0,0111967 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of lyase activity GO:0051339 160 83 3,000 1,476E-03 0,01138446 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 1,000 1,498E-03 0,01151799 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 1,000 1,498E-03 0,01148131 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 1,000 1,498E-03 0,01144486 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 1,000 1,498E-03 0,01140864 ! regulation of chemokine biosynthetic process GO:0045073 12 10 1,000 1,498E-03 0,01137265 ! positive regulation of survival gene product expression GO:0045885 23 10 1,000 1,498E-03 0,01133689 ! myeloid leukocyte mediated immunity GO:0002444 14 10 1,000 1,498E-03 0,01130135 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 1,000 1,498E-03 0,01126603 ! regulation of gliogenesis GO:0014013 23 10 1,000 1,498E-03 0,01123094 GO:0045685|regulation of glial cell differentiation, ! alpha-beta T cell activation GO:0046631 23 10 1,000 1,498E-03 0,01119606 ! response to dsRNA GO:0043331 20 10 1,000 1,498E-03 0,0111614 ! positive regulation of interleukin-6 production GO:0032755 14 10 1,000 1,498E-03 0,01112695 ! hindbrain morphogenesis GO:0021575 19 10 1,000 1,498E-03 0,01109271 ! salivary gland development GO:0007431 27 10 1,000 1,498E-03 0,01105868 ! positive regulation of acute inflammatory response GO:0002675 16 10 1,000 1,498E-03 0,01102486 ! positive regulation of leukocyte migration GO:0002687 25 10 1,000 1,498E-03 0,01099125 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 1,000 1,498E-03 0,01095784 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 1,000 1,498E-03 0,01092464 ! cerebellar cortex development GO:0021695 15 10 1,000 1,498E-03 0,01089163 ! regulation of cAMP metabolic process GO:0030814 168 84 3,000 1,543E-03 0,01118266 ! regulation of ligase activity GO:0051340 142 84 3,000 1,543E-03 0,01114908 ! positive regulation of cell activation GO:0050867 145 85 3,000 1,612E-03 0,01161176 GO:0002696|positive regulation of leukocyte activation, ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 2,000 1,681E-03 0,01206952 ! maintenance of protein location GO:0045185 91 40 2,000 1,681E-03 0,0120336 ! cytokinesis GO:0000910 72 40 2,000 1,681E-03 0,01199789 ! tube morphogenesis GO:0035239 176 86 3,000 1,683E-03 0,01197953 ! mitochondrion organization GO:0007005 148 86 3,000 1,683E-03 0,01194419 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 3,000 1,756E-03 0,01242644 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! T cell differentiation GO:0030217 81 41 2,000 1,805E-03 0,01273836 ! neuron fate specification GO:0048665 17 11 1,000 1,824E-03 0,0128341 ! detection of mechanical stimulus GO:0050982 22 11 1,000 1,824E-03 0,01279669 ! blood vessel remodeling GO:0001974 29 11 1,000 1,824E-03 0,01275949 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 1,000 1,824E-03 0,0127225 GO:0010812|negative regulation of cell-substrate adhesion, ! ventral spinal cord development GO:0021517 21 11 1,000 1,824E-03 0,01268573 ! regulation of intracellular pH GO:0051453 19 11 1,000 1,824E-03 0,01264918 ! negative regulation of ossification GO:0030279 26 11 1,000 1,824E-03 0,01261283 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 1,000 1,824E-03 0,01257669 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 1,000 1,824E-03 0,01254075 ! regulation of leukocyte migration GO:0002685 26 11 1,000 1,824E-03 0,01250503 ! nitric oxide mediated signal transduction GO:0007263 23 11 1,000 1,824E-03 0,0124695 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 1,000 1,824E-03 0,01243418 ! thymus development GO:0048538 27 11 1,000 1,824E-03 0,01239905 ! embryonic gut development GO:0048566 15 11 1,000 1,824E-03 0,01236412 ! defense response to Gram-positive bacterium GO:0050830 13 11 1,000 1,824E-03 0,01232939 ! lamellipodium assembly GO:0030032 20 11 1,000 1,824E-03 0,01229486 ! regulation of embryonic development GO:0045995 27 11 1,000 1,824E-03 0,01226051 ! positive regulation of transcription factor activity GO:0051091 62 42 2,000 1,936E-03 0,01297452 GO:0090047|positive regulation of transcription regulator activity, ! neuron migration GO:0001764 79 42 2,000 1,936E-03 0,01293848 ! regulation of myeloid cell differentiation GO:0045637 98 42 2,000 1,936E-03 0,01290264 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 3,000 1,989E-03 0,01321666 ! regulation of cell cycle process GO:0010564 149 90 3,000 1,989E-03 0,01318025 ! neural tube development GO:0021915 77 43 2,000 2,072E-03 0,01369704 ! positive regulation of cellular catabolic process GO:0031331 31 12 1,000 2,181E-03 0,01437479 ! virus-host interaction GO:0019048 29 12 1,000 2,181E-03 0,01433551 ! regulation of B cell proliferation GO:0030888 20 12 1,000 2,181E-03 0,01429645 ! dopamine receptor signaling pathway GO:0007212 28 12 1,000 2,181E-03 0,0142576 ! regulation of cell projection assembly GO:0060491 30 12 1,000 2,181E-03 0,01421896 ! hippocampus development GO:0021766 26 12 1,000 2,181E-03 0,01418053 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 1,000 2,181E-03 0,01414231 ! tyrosine metabolic process GO:0006570 16 12 1,000 2,181E-03 0,01410429 ! focal adhesion formation GO:0048041 35 12 1,000 2,181E-03 0,01406648 ! regulation of interleukin-12 production GO:0032655 19 12 1,000 2,181E-03 0,01402887 ! cranial nerve development GO:0021545 20 12 1,000 2,181E-03 0,01399146 ! gland morphogenesis GO:0022612 29 12 1,000 2,181E-03 0,01395425 ! aromatic amino acid family catabolic process GO:0009074 18 12 1,000 2,181E-03 0,01391723 ! spleen development GO:0048536 22 12 1,000 2,181E-03 0,01388041 ! digestive tract morphogenesis GO:0048546 26 12 1,000 2,181E-03 0,01384379 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 2,000 2,214E-03 0,01401998 ! maintenance of location in cell GO:0051651 97 44 2,000 2,214E-03 0,01398318 ! regulation of nucleotide metabolic process GO:0006140 182 93 3,000 2,242E-03 0,0141181 ! negative regulation of multicellular organismal process GO:0051241 166 93 3,000 2,242E-03 0,01408124 ! regulation of JAK-STAT cascade GO:0046425 70 45 2,000 2,362E-03 0,01480123 ! detection of stimulus involved in sensory perception GO:0050906 66 45 2,000 2,362E-03 0,01476279 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 2,000 2,362E-03 0,01472454 ! interphase of mitotic cell cycle GO:0051329 209 95 3,000 2,422E-03 0,01505767 ! forebrain development GO:0030900 188 95 3,000 2,422E-03 0,01501886 ! leukocyte differentiation GO:0002521 202 96 3,000 2,516E-03 0,01556086 ! detection of stimulus GO:0051606 151 96 3,000 2,516E-03 0,01552096 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 2,000 2,516E-03 0,01548378 ! regulation of gene-specific transcription GO:0032583 96 46 2,000 2,516E-03 0,01544428 ! pigmentation GO:0043473 100 46 2,000 2,516E-03 0,01540498 ! regulation of chemokine production GO:0032642 18 13 1,000 2,567E-03 0,01567728 ! lipid localization GO:0010876 28 13 1,000 2,567E-03 0,01563759 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 1,000 2,567E-03 0,0155981 ! endocrine pancreas development GO:0031018 22 13 1,000 2,567E-03 0,01555881 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 1,000 2,567E-03 0,01551972 ! response to X-ray GO:0010165 25 13 1,000 2,567E-03 0,01548082 ! exocrine system development GO:0035272 32 13 1,000 2,567E-03 0,01544212 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 1,000 2,567E-03 0,01540361 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! nucleoside triphosphate catabolic process GO:0009143 21 13 1,000 2,567E-03 0,0153653 ! regulation of cellular pH GO:0030641 22 13 1,000 2,567E-03 0,01532717 ! regulation of acute inflammatory response GO:0002673 21 13 1,000 2,567E-03 0,01528923 ! positive regulation of protein polymerization GO:0032273 25 13 1,000 2,567E-03 0,01525148 ! positive regulation of DNA binding GO:0043388 73 47 2,000 2,676E-03 0,0158602 ! regulation of adaptive immune response GO:0002819 84 47 2,000 2,676E-03 0,01582124 ! interphase GO:0051325 213 98 3,000 2,711E-03 0,01598725 ! cellular component disassembly GO:0022411 86 48 2,000 2,843E-03 0,01672155 ! morphogenesis of embryonic epithelium GO:0016331 91 48 2,000 2,843E-03 0,01668077 ! cell cycle arrest GO:0007050 213 100 3,000 2,916E-03 0,01707251 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 1,000 2,984E-03 0,01742366 GO:0060675|ureteric bud morphogenesis, ! negative regulation of protein import into nucleus GO:0042308 30 14 1,000 2,984E-03 0,01738147 ! cerebellum development GO:0021549 21 14 1,000 2,984E-03 0,01733949 ! regulation of T-helper 2 type immune response GO:0002828 24 14 1,000 2,984E-03 0,01729771 ! response to gamma radiation GO:0010332 28 14 1,000 2,984E-03 0,01725613 ! male genitalia development GO:0030539 24 14 1,000 2,984E-03 0,01721474 ! induction of apoptosis by extracellular signals GO:0008624 89 49 2,000 3,015E-03 0,01735397 ! detection of abiotic stimulus GO:0009582 74 49 2,000 3,015E-03 0,01731255 ! regulation of ossification GO:0030278 117 50 2,000 3,194E-03 0,01829512 ! negative regulation of immune system process GO:0002683 95 50 2,000 3,194E-03 0,01825167 ! positive regulation of cytokine production GO:0001819 86 50 2,000 3,194E-03 0,01820842 ! positive regulation of binding GO:0051099 78 51 2,000 3,379E-03 0,01921813 ! chromatin remodeling GO:0006338 109 51 2,000 3,379E-03 0,01917281 ! negative regulation of bone remodeling GO:0046851 33 15 1,000 3,429E-03 0,01941419 ! sulfate transport GO:0008272 23 15 1,000 3,429E-03 0,01936862 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 1,000 3,429E-03 0,01932326 ! pituitary gland development GO:0021983 29 15 1,000 3,429E-03 0,01927811 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 1,000 3,429E-03 0,01923317 ! regulation of exocytosis GO:0017157 22 15 1,000 3,429E-03 0,01918844 ! G1/S transition checkpoint GO:0031575 40 15 1,000 3,429E-03 0,01914392 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 1,000 3,429E-03 0,01909961 ! regulation of angiogenesis GO:0045765 114 52 2,000 3,57E-03 0,01983852 ! regulation of muscle contraction GO:0006937 81 52 2,000 3,57E-03 0,01979281 ! positive regulation of growth GO:0045927 90 52 2,000 3,57E-03 0,01974731 ! cartilage development GO:0051216 90 52 2,000 3,57E-03 0,01970202 ! cell maturation GO:0048469 100 53 2,000 3,768E-03 0,02074726 ! regulation of neuron apoptosis GO:0043523 100 53 2,000 3,768E-03 0,02069989 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 3,904E-03 0,02139735 ! bone remodeling GO:0046849 27 16 1,000 3,904E-03 0,02134872 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 1,000 3,904E-03 0,02130031 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 1,000 3,904E-03 0,02125212 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 1,000 3,904E-03 0,02120415 ! neuron recognition GO:0008038 35 16 1,000 3,904E-03 0,02115639 ! negative regulation of tissue remodeling GO:0034104 36 16 1,000 3,904E-03 0,02110885 ! defense response to virus GO:0051607 37 16 1,000 3,904E-03 0,02106152 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 2,000 3,973E-03 0,02138443 ! aging GO:0007568 103 55 2,000 4,184E-03 0,02247122 ! regulation of multicellular organism growth GO:0040014 85 55 2,000 4,184E-03 0,02242117 ! positive regulation of organelle organization GO:0010638 100 56 2,000 4,402E-03 0,02353666 ! positive regulation of protein complex assembly GO:0031334 32 17 1,000 4,408E-03 0,02351424 ! metencephalon development GO:0022037 30 17 1,000 4,408E-03 0,02346222 ! negative regulation of hormone secretion GO:0046888 25 17 1,000 4,408E-03 0,02341042 ! endothelial cell migration GO:0043542 28 17 1,000 4,408E-03 0,02335886 ! limbic system development GO:0021761 36 17 1,000 4,408E-03 0,02330752 ! cell differentiation in spinal cord GO:0021515 30 17 1,000 4,408E-03 0,02325641 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 1,000 4,408E-03 0,02320552 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 1,000 4,408E-03 0,02315485 ! negative regulation of protein catabolic process GO:0042177 40 17 1,000 4,408E-03 0,02310441 ! genitalia development GO:0048806 30 17 1,000 4,408E-03 0,02305418 ! neural crest cell migration GO:0001755 37 17 1,000 4,408E-03 0,02300417 ! branched chain family amino acid metabolic process GO:0009081 33 17 1,000 4,408E-03 0,02295438 ! regulation of bone remodeling GO:0046850 137 57 2,000 4,627E-03 0,02404355 ! regulation of tissue remodeling GO:0034103 140 58 2,000 4,858E-03 0,02519235 ! neuron maturation GO:0042551 42 18 1,000 4,94E-03 0,02555837 ! positive regulation of anti-apoptosis GO:0045768 39 18 1,000 4,94E-03 0,02550352 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 1,000 4,94E-03 0,02544891 ! protein amino acid ADP-ribosylation GO:0006471 33 18 1,000 4,94E-03 0,02539453 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 1,000 4,94E-03 0,02534038 GO:0050886|endocrine process, ! epidermis morphogenesis GO:0048730 40 18 1,000 4,94E-03 0,02528647 ! cell-substrate junction assembly GO:0007044 54 18 1,000 4,94E-03 0,02523278 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 1,000 4,94E-03 0,02517932 ! long-chain fatty acid transport GO:0015909 31 18 1,000 4,94E-03 0,02512609 ! regulation of immunoglobulin production GO:0002637 43 18 1,000 4,94E-03 0,02507308 ! aromatic compound catabolic process GO:0019439 27 18 1,000 4,94E-03 0,0250203 ! nerve development GO:0021675 28 18 1,000 4,94E-03 0,02496773 ! skeletal system morphogenesis GO:0048705 105 59 2,000 5,097E-03 0,02570836 ! DNA catabolic process GO:0006308 86 59 2,000 5,097E-03 0,02565458 ! DNA damage response, signal transduction GO:0042770 128 60 2,000 5,342E-03 0,02683344 ! regulation of heart contraction GO:0008016 110 60 2,000 5,342E-03 0,02677754 ! positive regulation of translation GO:0045727 30 19 1,000 5,499E-03 0,02750885 ! skin development GO:0043588 36 19 1,000 5,499E-03 0,02745178 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 1,000 5,499E-03 0,02739494 ! pigmentation during development GO:0048066 41 19 1,000 5,499E-03 0,02733834 ! actin filament bundle formation GO:0051017 42 19 1,000 5,499E-03 0,02728197 ! neuromuscular junction development GO:0007528 34 19 1,000 5,499E-03 0,02722584 ! response to lipopolysaccharide GO:0032496 30 19 1,000 5,499E-03 0,02716993 ! regulation of endothelial cell migration GO:0010594 44 19 1,000 5,499E-03 0,02711426 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 1,000 5,499E-03 0,02705881 ! peptide hormone secretion GO:0030072 31 19 1,000 5,499E-03 0,02700359 ! regulation of homeostatic process GO:0032844 134 62 2,000 5,854E-03 0,02868527 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 1,000 6,087E-03 0,02976717 ! response to alkaloid GO:0043279 38 20 1,000 6,087E-03 0,02970679 ! pancreas development GO:0031016 35 20 1,000 6,087E-03 0,02964665 ! cellular response to starvation GO:0009267 33 20 1,000 6,087E-03 0,02958676 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 1,000 6,087E-03 0,02952711 ! peptide secretion GO:0002790 35 20 1,000 6,087E-03 0,0294677 ! regulation of interleukin-2 production GO:0032663 35 20 1,000 6,087E-03 0,02940853 ! diencephalon development GO:0021536 34 20 1,000 6,087E-03 0,02934959 ! detection of chemical stimulus GO:0009593 37 20 1,000 6,087E-03 0,02929089 ! camera-type eye morphogenesis GO:0048593 42 20 1,000 6,087E-03 0,02923243 ! negative regulation of translation GO:0017148 29 20 1,000 6,087E-03 0,0291742 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 1,000 6,087E-03 0,0291162 ! regulation of mitosis GO:0007088 105 63 2,000 6,12E-03 0,02921753 GO:0051783|regulation of nuclear division, ! detection of external stimulus GO:0009581 91 63 2,000 6,12E-03 0,02915967 ! embryonic limb morphogenesis GO:0030326 125 65 2,000 6,675E-03 0,03173844 GO:0035113|embryonic appendage morphogenesis, ! myeloid cell differentiation GO:0030099 111 65 2,000 6,675E-03 0,03167584 ! hormone secretion GO:0046879 38 21 1,000 6,702E-03 0,03174191 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 1,000 6,702E-03 0,03167954 ! cell aging GO:0007569 44 21 1,000 6,702E-03 0,03161743 ! regulation of vasoconstriction GO:0019229 39 21 1,000 6,702E-03 0,03155555 ! collagen fibril organization GO:0030199 59 21 1,000 6,702E-03 0,03149392 ! negative regulation of intracellular transport GO:0032387 41 21 1,000 6,702E-03 0,03143253 ! positive regulation of osteoblast differentiation GO:0045669 49 21 1,000 6,702E-03 0,03137138 ! developmental maturation GO:0021700 116 66 2,000 6,963E-03 0,03252955 ! activation of MAPK activity GO:0000187 115 67 2,000 7,258E-03 0,03384363 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 1,000 7,344E-03 0,03417654 ! glutamate signaling pathway GO:0007215 41 22 1,000 7,344E-03 0,03411056 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 1,000 7,344E-03 0,03404483 ! positive regulation of cytoskeleton organization GO:0051495 48 22 1,000 7,344E-03 0,03397936 ! vesicle docking during exocytosis GO:0006904 41 22 1,000 7,344E-03 0,03391414 ! renal system process GO:0003014 41 22 1,000 7,344E-03 0,03384917 ! positive regulation of B cell activation GO:0050871 38 22 1,000 7,344E-03 0,03378445 ! aromatic amino acid family metabolic process GO:0009072 32 22 1,000 7,344E-03 0,03371998 ! protein stabilization GO:0050821 39 22 1,000 7,344E-03 0,03365575 ! negative regulation of ligase activity GO:0051352 112 68 2,000 7,561E-03 0,03458465 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 2,000 7,561E-03 0,03451903 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 1,000 8,012E-03 0,03651095 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 8,012E-03 0,03644193 ! myeloid leukocyte differentiation GO:0002573 40 23 1,000 8,012E-03 0,03637318 ! regulation of anti-apoptosis GO:0045767 53 23 1,000 8,012E-03 0,03630468 ! regulation of cell-matrix adhesion GO:0001952 78 23 1,000 8,012E-03 0,03623644 GO:0010810|regulation of cell-substrate adhesion, ! activation of pro-apoptotic gene products GO:0008633 47 23 1,000 8,012E-03 0,03616845 ! sex determination GO:0007530 47 23 1,000 8,012E-03 0,03610072 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 1,000 8,012E-03 0,03603324 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 1,000 8,012E-03 0,03596601 ! regulation of interleukin-6 production GO:0032675 29 23 1,000 8,012E-03 0,03589904 ! synaptic vesicle transport GO:0048489 46 23 1,000 8,012E-03 0,03583231 ! fatty acid transport GO:0015908 44 23 1,000 8,012E-03 0,03576583 ! platelet activation GO:0030168 37 23 1,000 8,012E-03 0,0356996 ! regulation of bone mineralization GO:0030500 49 23 1,000 8,012E-03 0,03563361 ! hormone transport GO:0009914 40 23 1,000 8,012E-03 0,03556787 ! negative regulation of catabolic process GO:0009895 50 23 1,000 8,012E-03 0,03550236 ! appendage morphogenesis GO:0035107 135 70 2,000 8,188E-03 0,03621548 GO:0035108|limb morphogenesis, ! appendage development GO:0048736 136 71 2,000 8,513E-03 0,03758328 GO:0060173|limb development, ! regulation of cellular catabolic process GO:0031329 52 24 1,000 8,707E-03 0,03836929 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 1,000 8,707E-03 0,03829915 ! vesicle docking GO:0048278 47 24 1,000 8,707E-03 0,03822926 ! spinal cord development GO:0021510 47 24 1,000 8,707E-03 0,03815962 ! pallium development GO:0021543 49 24 1,000 8,707E-03 0,03809024 ! leukocyte homeostasis GO:0001776 44 24 1,000 8,707E-03 0,03802111 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 2,000 8,846E-03 0,03855535 ! myelination GO:0042552 45 25 1,000 9,428E-03 0,04101994 ! dicarboxylic acid metabolic process GO:0043648 42 25 1,000 9,428E-03 0,0409459 ! phototransduction GO:0007602 33 25 1,000 9,428E-03 0,04087212 ! negative regulation of DNA replication GO:0008156 42 25 1,000 9,428E-03 0,04079861 ! response to starvation GO:0042594 42 25 1,000 9,428E-03 0,04072536 ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 9,428E-03 0,04065238 ! neural crest cell development GO:0014032 54 25 1,000 9,428E-03 0,04057966 GO:0014033|neural crest cell differentiation, ! interaction with host GO:0051701 62 25 1,000 9,428E-03 0,04050719 ! regulation of biomineral formation GO:0070167 51 25 1,000 9,428E-03 0,04043499 ! positive regulation of protein secretion GO:0050714 36 25 1,000 9,428E-03 0,04036304 ! cellular response to nutrient levels GO:0031669 41 25 1,000 9,428E-03 0,04029135 ! meiosis GO:0007126 121 74 2,000 9,533E-03 0,04066705 GO:0051327|M phase of meiotic cell cycle, ! exocytosis GO:0006887 133 74 2,000 9,533E-03 0,04059508 ! meiotic cell cycle GO:0051321 122 75 2,000 9,888E-03 0,04203247 ! lymphocyte differentiation GO:0030098 167 75 2,000 9,888E-03 0,04195834 ! positive regulation of MAPKKK cascade GO:0043410 47 26 1,000 0,01017464 0,04309891 ! positive regulation of nuclear division GO:0051785 40 26 1,000 0,01017464 0,04302317 GO:0045840|positive regulation of mitosis, ! regulation of osteoblast differentiation GO:0045667 65 26 1,000 0,01017464 0,04294769 ! regulation of catabolic process GO:0009894 161 76 2,000 0,01025056 0,04319239 ! neuron fate commitment GO:0048663 48 27 1,000 0,01094652 0,04604426 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 1,000 0,01094652 0,04596391 ! positive regulation of cell projection organization GO:0031346 58 27 1,000 0,01094652 0,04588383 ! fat cell differentiation GO:0045444 50 27 1,000 0,01094652 0,04580403 ! mitochondrial membrane organization GO:0007006 57 27 1,000 0,01094652 0,04572451 ! base-excision repair GO:0006284 41 27 1,000 0,01094652 0,04564527 ! negative regulation of neuron differentiation GO:0045665 42 27 1,000 0,01094652 0,04556629 ! negative regulation of organelle organization GO:0010639 161 78 2,000 0,01099877 0,04570475 ! response to steroid hormone stimulus GO:0048545 137 78 2,000 0,01099877 0,04562595 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 1,000 0,01174342 0,0486311 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 0,01174342 0,04854754 ! regulation of systemic arterial blood pressure GO:0003073 54 28 1,000 0,01174342 0,04846427 ! response to metal ion GO:0010038 140 80 2,000 0,01177778 0,04852284 ! inorganic anion transport GO:0015698 138 80 2,000 0,01177778 0,0484399 ! regulation of neuron differentiation GO:0045664 167 81 2,000 0,0121789 0,05000413 ! regulation of pH GO:0006885 43 29 1,000 0,01256503 0,05150164 ! cellular iron ion homeostasis GO:0006879 51 29 1,000 0,01256503 0,05141405 ! regulation of production of molecular mediator of immune response GO:0002700 61 29 1,000 0,01256503 0,05132676 ! response to organic cyclic substance GO:0014070 55 29 1,000 0,01256503 0,05123977 ! detection of light stimulus GO:0009583 38 29 1,000 0,01256503 0,05115307 ! cellular response to extracellular stimulus GO:0031668 48 29 1,000 0,01256503 0,05106666 ! membrane docking GO:0022406 61 30 1,000 0,01341104 0,05441307 ! cell junction assembly GO:0034329 78 30 1,000 0,01341104 0,05432147 ! acute-phase response GO:0006953 49 30 1,000 0,01341104 0,05423017 ! positive regulation of multicellular organism growth GO:0040018 51 30 1,000 0,01341104 0,05413918 ! ensheathment of neurons GO:0007272 57 30 1,000 0,01341104 0,0540485 GO:0008366|axon ensheathment, ! neurotransmitter secretion GO:0007269 48 30 1,000 0,01341104 0,05395811 ! eye morphogenesis GO:0048592 60 30 1,000 0,01341104 0,05386803 ! peptide transport GO:0015833 55 31 1,000 0,01428112 0,0572673 ! iron ion homeostasis GO:0055072 54 31 1,000 0,01428112 0,05717202 ! mesoderm formation GO:0001707 69 31 1,000 0,01428112 0,05707705 ! response to inorganic substance GO:0010035 153 86 2,000 0,01430147 0,05706358 ! response to ionizing radiation GO:0010212 65 32 1,000 0,01517498 0,06044869 ! response to mechanical stimulus GO:0009612 57 32 1,000 0,01517498 0,06034878 ! hindbrain development GO:0030902 61 32 1,000 0,01517498 0,06024919 ! positive regulation of catabolic process GO:0009896 64 32 1,000 0,01517498 0,06014994 ! regulation of cell adhesion GO:0030155 212 89 2,000 0,0156693 0,06200712 ! DNA damage checkpoint GO:0000077 71 33 1,000 0,01609231 0,06357652 ! positive regulation of gene-specific transcription GO:0043193 65 33 1,000 0,01609231 0,0634723 ! formation of primary germ layer GO:0001704 72 33 1,000 0,01609231 0,06336842 ! cell fate specification GO:0001708 52 33 1,000 0,01609231 0,06326487 ! mesoderm morphogenesis GO:0048332 76 34 1,000 0,0170328 0,06685306 ! mismatch repair GO:0006298 46 34 1,000 0,0170328 0,06674418 ! placenta development GO:0001890 53 34 1,000 0,0170328 0,06663565 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 1,000 0,0170328 0,06652747 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 2,000 0,0176039 0,06864664 GO:0010498|proteasomal protein catabolic process, ! regulation of smooth muscle cell proliferation GO:0048660 59 35 1,000 0,01799616 0,07006271 ! negative regulation of secretion GO:0051048 63 35 1,000 0,01799616 0,06994952 ! negative regulation of DNA metabolic process GO:0051053 61 35 1,000 0,01799616 0,0698367 ! negative regulation of cell adhesion GO:0007162 81 35 1,000 0,01799616 0,06972424 ! embryonic skeletal system morphogenesis GO:0048704 59 35 1,000 0,01799616 0,06961214 ! negative regulation of hydrolase activity GO:0051346 62 35 1,000 0,01799616 0,06950041 ! calcium-mediated signaling GO:0019722 62 35 1,000 0,01799616 0,06938903 ! neural tube formation GO:0001841 67 35 1,000 0,01799616 0,06927801 ! mitotic sister chromatid segregation GO:0000070 57 36 1,000 0,01898208 0,07295667 ! cell junction organization GO:0034330 86 36 1,000 0,01898208 0,07284031 ! DNA integrity checkpoint GO:0031570 75 36 1,000 0,01898208 0,07272432 ! sister chromatid segregation GO:0000819 58 37 1,000 0,01999026 0,07646514 ! actomyosin structure organization GO:0031032 62 37 1,000 0,01999026 0,07634377 ! monovalent inorganic cation homeostasis GO:0055067 58 37 1,000 0,01999026 0,07622278 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 2,000 0,02074459 0,07897386 ! Golgi vesicle transport GO:0048193 207 99 2,000 0,02074459 0,07884909 ! lipid homeostasis GO:0055088 67 38 1,000 0,02102043 0,07977154 ! nucleotide catabolic process GO:0009166 61 38 1,000 0,02102043 0,07964591 ! learning GO:0007612 77 39 1,000 0,02207228 0,08349986 ! ear morphogenesis GO:0042471 60 39 1,000 0,02207228 0,08336878 ! development of primary male sexual characteristics GO:0046546 66 39 1,000 0,02207228 0,0832381 ! regulation of action potential in neuron GO:0019228 73 39 1,000 0,02207228 0,08310784 ! Rho protein signal transduction GO:0007266 74 39 1,000 0,02207228 0,08297798 ! regulation of hormone secretion GO:0046883 62 40 1,000 0,02314553 0,08687699 ! multicellular organismal metabolic process GO:0044236 57 40 1,000 0,02314553 0,08674167 ! mesenchymal cell development GO:0014031 87 40 1,000 0,02314553 0,08660677 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 1,000 0,0242399 0,09056087 ! cellular amide metabolic process GO:0043603 67 41 1,000 0,0242399 0,09042046 ! regulation of tube size GO:0035150 71 42 1,000 0,0253551 0,094434 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 1,000 0,0253551 0,09428805 ! regulation of protein secretion GO:0050708 71 42 1,000 0,0253551 0,09414254 ! epithelial cell differentiation GO:0030855 79 43 1,000 0,02649085 0,09820799 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 1,000 0,02649085 0,0980569 ! glucose transport GO:0015758 65 43 1,000 0,02649085 0,09790627 ! hexose transport GO:0008645 67 44 1,000 0,02764688 0,10202206 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 1,000 0,02764688 0,10186582 ! male sex differentiation GO:0046661 76 44 1,000 0,02764688 0,10171006 ! double-strand break repair GO:0006302 81 44 1,000 0,02764688 0,10155478 ! B cell differentiation GO:0030183 107 44 1,000 0,02764688 0,10139997 ! JAK-STAT cascade GO:0007259 71 44 1,000 0,02764688 0,10124563 ! developmental growth GO:0048589 82 44 1,000 0,02764688 0,10109177 ! regulation of actin filament polymerization GO:0030833 87 45 1,000 0,0288229 0,10523202 ! branching morphogenesis of a tube GO:0048754 97 45 1,000 0,0288229 0,10507258 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,02904393 0,10571813 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,02904393 0,10555844 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,02904393 0,10539923 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,02904393 0,10524049 ! neuron fate determination GO:0048664 7 5 0,000 0,02904393 0,10508224 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02904393 0,10492446 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,02904393 0,10476715 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,02904393 0,10461031 ! polyol transport GO:0015791 12 5 0,000 0,02904393 0,10445394 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,02904393 0,10429804 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,02904393 0,1041426 ! response to superoxide GO:0000303 10 5 0,000 0,02904393 0,10398763 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,02904393 0,10383312 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,02904393 0,10367906 GO:0045940|positive regulation of steroid metabolic process, ! tongue development GO:0043586 8 5 0,000 0,02904393 0,10352546 ! female meiosis GO:0007143 7 5 0,000 0,02904393 0,10337232 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,02904393 0,10321963 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,02904393 0,10306739 ! cobalt ion transport GO:0006824 11 5 0,000 0,02904393 0,10291559 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,02904393 0,10276425 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,02904393 0,10261334 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,02904393 0,10246288 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,02904393 0,10231287 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,02904393 0,10216329 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,02904393 0,10201414 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,02904393 0,10186543 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,02904393 0,10171716 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,02904393 0,10156931 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,02904393 0,1014219 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02904393 0,10127491 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! negative chemotaxis GO:0050919 14 5 0,000 0,02904393 0,10112835 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,02904393 0,10098221 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,02904393 0,10083649 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,02904393 0,10069119 ! behavioral response to pain GO:0048266 9 5 0,000 0,02904393 0,10054631 ! clathrin coat assembly GO:0048268 14 5 0,000 0,02904393 0,10040185 ! Notch receptor processing GO:0007220 8 5 0,000 0,02904393 0,1002578 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02904393 0,10011416 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,02904393 0,09997094 ! micturition GO:0060073 9 5 0,000 0,02904393 0,09982812 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,02904393 0,09968572 ! copulation GO:0007620 9 5 0,000 0,02904393 0,09954371 ! glial cell fate commitment GO:0021781 13 5 0,000 0,02904393 0,09940212 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,02904393 0,09926092 ! spermidine metabolic process GO:0008216 7 5 0,000 0,02904393 0,09912012 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,02904393 0,09897973 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,02904393 0,09883973 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,02904393 0,09870012 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,02904393 0,09856091 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,02904393 0,09842209 ! grooming behavior GO:0007625 6 5 0,000 0,02904393 0,09828367 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,02904393 0,09814563 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,02904393 0,09800798 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02904393 0,09787071 ! lymph vessel development GO:0001945 10 5 0,000 0,02904393 0,09773383 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,02904393 0,09759733 ! endochondral ossification GO:0001958 16 5 0,000 0,02904393 0,09746121 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,02904393 0,09732547 ! anagen GO:0042640 6 5 0,000 0,02904393 0,09719011 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,02904393 0,09705512 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,02904393 0,09692051 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,02904393 0,09678627 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,02904393 0,0966524 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,02904393 0,0965189 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,02904393 0,09638578 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,02904393 0,09625301 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,02904393 0,09612061 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,02904393 0,09598858 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,02904393 0,09585691 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,02904393 0,0957256 GO:0046516|hypusine metabolic process, ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,02904393 0,09559465 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,02904393 0,09546405 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,02904393 0,09533382 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,02904393 0,09520393 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,02904393 0,0950744 ! histidine catabolic process GO:0006548 6 5 0,000 0,02904393 0,09494523 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,02904393 0,0948164 ! microvillus organization GO:0032528 7 5 0,000 0,02904393 0,09468792 GO:0030033|microvillus assembly, ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,02904393 0,09455979 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,02904393 0,09443201 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,02904393 0,09430457 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,02904393 0,09417748 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,02904393 0,09405072 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,02904393 0,09392431 ! polyol catabolic process GO:0046174 7 5 0,000 0,02904393 0,09379824 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,02904393 0,0936725 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,02904393 0,0935471 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,02904393 0,09342204 ! muscle cell migration GO:0014812 8 5 0,000 0,02904393 0,09329731 ! mitochondrial fission GO:0000266 8 5 0,000 0,02904393 0,09317292 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,02904393 0,09304885 ! mRNA transcription GO:0009299 9 5 0,000 0,02904393 0,09292512 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,02904393 0,09280171 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,02904393 0,09267863 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,02904393 0,09255588 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,02904393 0,09243345 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,02904393 0,09231134 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,02904393 0,09218956 ! response to food GO:0032094 6 5 0,000 0,02904393 0,0920681 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,02904393 0,09194696 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,02904393 0,09182613 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of phospholipase A2 activity GO:0032429 13 5 0,000 0,02904393 0,09170563 ! forebrain neuron development GO:0021884 13 5 0,000 0,02904393 0,09158544 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,02904393 0,09146556 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,02904393 0,091346 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,02904393 0,09122675 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02904393 0,09110781 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,02904393 0,09098918 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,02904393 0,09087085 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02904393 0,09075284 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,02904393 0,09063513 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,02904393 0,09051773 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,02904393 0,09040063 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,02904393 0,09028383 ! basic amino acid transport GO:0015802 11 5 0,000 0,02904393 0,09016734 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,02904393 0,09005114 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,02904393 0,08993525 ! depyrimidination GO:0045008 10 5 0,000 0,02904393 0,08981965 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,02904393 0,08970435 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02904393 0,08958934 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,02904393 0,08947463 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,02904393 0,08936021 GO:0006882|cellular zinc ion homeostasis, ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,02904393 0,08924609 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02904393 0,08913225 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,02904393 0,08901871 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,02904393 0,08890545 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,02904393 0,08879249 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,02904393 0,08867981 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,02904393 0,08856741 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02904393 0,0884553 ! response to arsenic GO:0046685 10 5 0,000 0,02904393 0,08834347 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,02904393 0,08823193 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,02904393 0,08812066 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,02904393 0,08800968 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,02904393 0,08789898 ! response to cadmium ion GO:0046686 7 5 0,000 0,02904393 0,08778855 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,02904393 0,0876784 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,02904393 0,08756853 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,02904393 0,08745893 ! decidualization GO:0046697 11 5 0,000 0,02904393 0,08734961 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,02904393 0,08724056 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,02904393 0,08713178 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,02904393 0,08702327 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,02904393 0,08691503 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,02904393 0,08680706 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,02904393 0,08669936 ! neural tube patterning GO:0021532 7 5 0,000 0,02904393 0,08659193 ! embryonic cleavage GO:0040016 6 5 0,000 0,02904393 0,08648476 ! peroxisome fission GO:0016559 5 5 0,000 0,02904393 0,08637786 ! histone demethylation GO:0016577 10 5 0,000 0,02904393 0,08627122 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,02904393 0,08616484 ! mitotic recombination GO:0006312 9 5 0,000 0,02904393 0,08605873 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,02904393 0,08595287 ! metaphase plate congression GO:0051310 7 5 0,000 0,02904393 0,08584728 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02904393 0,08574195 GO:0032374|regulation of cholesterol transport, ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,02904393 0,08563687 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,02904393 0,08553205 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,02904393 0,08542749 ! muscle cell proliferation GO:0033002 11 5 0,000 0,02904393 0,08532318 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,02904393 0,08521913 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,02904393 0,08511533 ! plasminogen activation GO:0031639 5 5 0,000 0,02904393 0,08501178 ! B cell homeostasis GO:0001782 13 5 0,000 0,02904393 0,08490849 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,02904393 0,08480545 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,02904393 0,08470265 ! metaphase GO:0051323 8 5 0,000 0,02904393 0,08460011 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,02904393 0,08449781 ! cellular response to nutrient GO:0031670 8 5 0,000 0,02904393 0,08439576 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,02904393 0,08429395 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,02904393 0,08419239 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,02904393 0,08409108 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,02904393 0,08399001 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,02904393 0,08388918 ! response to redox state GO:0051775 5 5 0,000 0,02904393 0,08378859 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,02904393 0,08368825 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,02904393 0,08358814 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,02904393 0,08348828 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,02904393 0,08338865 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02904393 0,08328926 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,02904393 0,0831901 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02904393 0,08309119 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,02904393 0,0829925 ! striatum development GO:0021756 9 5 0,000 0,02904393 0,08289405 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,02904393 0,08279584 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,02904393 0,08269785 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,02904393 0,0826001 ! glial cell migration GO:0008347 11 5 0,000 0,02904393 0,08250258 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,02904393 0,08240529 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,02904393 0,08230823 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,02904393 0,0822114 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,02904393 0,08211479 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,02904393 0,08201841 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,02904393 0,08192226 ! neuroprotection GO:0043526 6 5 0,000 0,02904393 0,08182633 ! neural plate development GO:0001840 8 5 0,000 0,02904393 0,08173063 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,02904393 0,08163515 ! regulation of sensory perception GO:0051931 7 5 0,000 0,02904393 0,08153989 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,02904393 0,08144486 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,02904393 0,08135004 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,02904393 0,08125545 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,02904393 0,08116108 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,02904393 0,08106692 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,02904393 0,08097299 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,02904393 0,08087927 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,02904393 0,08078577 ! spindle assembly GO:0051225 6 5 0,000 0,02904393 0,08069248 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,02904393 0,08059941 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,02904393 0,08050655 GO:0022011|myelination in the peripheral nervous system, ! drug metabolic process GO:0017144 6 5 0,000 0,02904393 0,08041391 ! phospholipid scrambling GO:0017121 8 5 0,000 0,02904393 0,08032148 ! organ regeneration GO:0031100 7 5 0,000 0,02904393 0,08022926 ! carnitine metabolic process GO:0009437 7 5 0,000 0,02904393 0,08013726 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,02904393 0,08004546 ! epidermal cell differentiation GO:0009913 68 46 1,000 0,03001866 0,08263718 ! response to calcium ion GO:0051592 81 47 1,000 0,03123387 0,08588423 ! endosome transport GO:0016197 108 47 1,000 0,03123387 0,08578619 ! vascular process in circulatory system GO:0003018 80 47 1,000 0,03123387 0,08568837 ! JNK cascade GO:0007254 91 47 1,000 0,03123387 0,08559077 ! protein homooligomerization GO:0051260 76 47 1,000 0,03123387 0,0854934 ! positive regulation of cell cycle GO:0045787 89 48 1,000 0,03246828 0,08877123 ! mitochondrial transport GO:0006839 82 48 1,000 0,03246828 0,08867047 ! regulation of action potential GO:0001508 95 49 1,000 0,03372161 0,09198889 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 1,000 0,03372161 0,09188471 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,03475126 0,09458318 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,03475126 0,09447631 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,03475126 0,09436967 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,03475126 0,09426328 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,03475126 0,09415713 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,03475126 0,09405122 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,03475126 0,09394554 ! sleep GO:0030431 13 6 0,000 0,03475126 0,0938401 ! response to oxygen radical GO:0000305 11 6 0,000 0,03475126 0,0937349 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,03475126 0,09362993 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,03475126 0,0935252 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,03475126 0,09342071 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,03475126 0,09331644 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,03475126 0,09321241 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,03475126 0,09310861 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,03475126 0,09300504 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,03475126 0,0929017 ! male meiosis GO:0007140 7 6 0,000 0,03475126 0,09279859 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,03475126 0,09269571 ! response to zinc ion GO:0010043 9 6 0,000 0,03475126 0,09259306 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,03475126 0,09249063 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,03475126 0,09238843 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,03475126 0,09228646 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,03475126 0,09218471 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,03475126 0,09208318 ! malate metabolic process GO:0006108 11 6 0,000 0,03475126 0,09198188 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,03475126 0,0918808 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,03475126 0,09177995 ! protein refolding GO:0042026 15 6 0,000 0,03475126 0,09167931 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,03475126 0,0915789 ! opsonization GO:0008228 8 6 0,000 0,03475126 0,0914787 ! mating behavior GO:0007617 7 6 0,000 0,03475126 0,09137872 ! neuron remodeling GO:0016322 15 6 0,000 0,03475126 0,09127896 ! erythrocyte maturation GO:0043249 7 6 0,000 0,03475126 0,09117942 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,03475126 0,0910801 ! equilibrioception GO:0050957 14 6 0,000 0,03475126 0,09098099 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,03475126 0,0908821 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,03475126 0,09078342 ! photoreceptor cell development GO:0042461 10 6 0,000 0,03475126 0,09068496 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,03475126 0,09058671 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,03475126 0,09048867 ! response to interferon-gamma GO:0034341 15 6 0,000 0,03475126 0,09039084 ! toxin metabolic process GO:0009404 11 6 0,000 0,03475126 0,09029323 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,03475126 0,09019583 ! nuclear migration GO:0007097 12 6 0,000 0,03475126 0,09009863 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,03475126 0,09000165 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,03475126 0,08990487 ! thymic T cell selection GO:0045061 12 6 0,000 0,03475126 0,0898083 ! protein lipoylation GO:0009249 10 6 0,000 0,03475126 0,08971194 ! cysteine metabolic process GO:0006534 10 6 0,000 0,03475126 0,08961579 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,03475126 0,08951984 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,03475126 0,0894241 ! glutamate catabolic process GO:0006538 10 6 0,000 0,03475126 0,08932856 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,03475126 0,08923322 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,03475126 0,08913809 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,03475126 0,08904316 ! response to pH GO:0009268 10 6 0,000 0,03475126 0,08894844 ! hyperosmotic response GO:0006972 9 6 0,000 0,03475126 0,08885391 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,03475126 0,08875959 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,03475126 0,08866546 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,03475126 0,08857154 ! urea metabolic process GO:0019627 7 6 0,000 0,03475126 0,08847781 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,03475126 0,08838428 ! neutrophil activation GO:0042119 8 6 0,000 0,03475126 0,08829095 ! regulation of appetite GO:0032098 9 6 0,000 0,03475126 0,08819782 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,03475126 0,08810488 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,03475126 0,08801214 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,03475126 0,08791959 ! neuron apoptosis GO:0051402 9 6 0,000 0,03475126 0,08782724 ! nucleoside salvage GO:0043174 9 6 0,000 0,03475126 0,08773508 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,03475126 0,08764311 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,03475126 0,08755134 ! T cell mediated immunity GO:0002456 16 6 0,000 0,03475126 0,08745976 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,03475126 0,08736837 GO:0010543|regulation of platelet activation, ! carnitine transport GO:0015879 10 6 0,000 0,03475126 0,08727717 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,03475126 0,08718616 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,03475126 0,08709535 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,03475126 0,08700472 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,03475126 0,08691427 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,03475126 0,08682402 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,03475126 0,08673395 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,03475126 0,08664407 ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,03475126 0,08655438 ! neural nucleus development GO:0048857 14 6 0,000 0,03475126 0,08646487 ! response to UV-C GO:0010225 11 6 0,000 0,03475126 0,08637555 ! astrocyte development GO:0014002 15 6 0,000 0,03475126 0,08628641 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,03475126 0,08619745 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,03475126 0,08610868 ! interaction with symbiont GO:0051702 13 6 0,000 0,03475126 0,08602009 ! regulation of dendrite development GO:0050773 16 6 0,000 0,03475126 0,08593169 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,03475126 0,08584346 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,03475126 0,08575542 ! response to copper ion GO:0046688 10 6 0,000 0,03475126 0,08566755 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,03475126 0,08557987 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,03475126 0,08549236 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,03475126 0,08540504 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,03475126 0,08531789 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,03475126 0,08523092 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,03475126 0,08514413 ! hair follicle maturation GO:0048820 7 6 0,000 0,03475126 0,08505751 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,03475126 0,08497107 ! Schwann cell development GO:0014044 15 6 0,000 0,03475126 0,0848848 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,03475126 0,08479871 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,03475126 0,0847128 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,03475126 0,08462706 ! subpallium development GO:0021544 10 6 0,000 0,03475126 0,08454149 ! histone ubiquitination GO:0016574 8 6 0,000 0,03475126 0,08445609 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,03475126 0,08437087 ! maintenance of organ identity GO:0048496 9 6 0,000 0,03475126 0,08428582 ! G2 phase GO:0051319 16 6 0,000 0,03475126 0,08420094 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,03475126 0,08411623 ! establishment of planar polarity GO:0001736 7 6 0,000 0,03475126 0,08403169 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,03475126 0,08394732 ! membrane to membrane docking GO:0022614 14 6 0,000 0,03475126 0,08386312 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,03475126 0,08377909 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,03475126 0,08369523 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,03475126 0,08361153 ! receptor internalization GO:0031623 10 6 0,000 0,03475126 0,083528 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,03475126 0,08344464 GO:0031272|regulation of pseudopodium assembly, ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,03475126 0,08336145 GO:0043011|myeloid dendritic cell differentiation, ! protein deubiquitination GO:0016579 14 6 0,000 0,03475126 0,08327842 ! protein destabilization GO:0031648 9 6 0,000 0,03475126 0,08319555 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,03475126 0,08311285 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,03475126 0,08303032 ! regulation of viral transcription GO:0046782 10 6 0,000 0,03475126 0,08294795 ! progesterone metabolic process GO:0042448 10 6 0,000 0,03475126 0,08286574 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,03475126 0,08278369 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,03475126 0,08270181 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,03475126 0,08262009 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,03475126 0,08253853 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,03475126 0,08245713 ! determination of adult lifespan GO:0008340 15 6 0,000 0,03475126 0,08237589 ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,03475126 0,08229481 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,03475126 0,0822139 ! catecholamine transport GO:0051937 9 6 0,000 0,03475126 0,08213313 ! sensory cilium assembly GO:0035058 10 6 0,000 0,03475126 0,08205253 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,03475126 0,08197209 ! maternal placenta development GO:0001893 12 6 0,000 0,03475126 0,0818918 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,03475126 0,08181167 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,03475126 0,0817317 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,03475126 0,08165189 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,03475126 0,08157223 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,03475126 0,08149272 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,03475126 0,08141337 ! regulation of cell projection organization GO:0031344 121 50 1,000 0,03499361 0,08190139 ! embryonic skeletal system development GO:0048706 85 51 1,000 0,03628401 0,084839 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 1,000 0,03628401 0,08475664 ! morphogenesis of a branching structure GO:0001763 111 52 1,000 0,03759256 0,08772813 ! amino acid activation GO:0043038 92 52 1,000 0,03759256 0,08764313 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! synapse organization GO:0050808 85 52 1,000 0,03759256 0,08755828 ! regulation of translational initiation GO:0006446 82 53 1,000 0,038919 0,09056008 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 1,000 0,038919 0,09047258 ! regulation of protein polymerization GO:0032271 103 53 1,000 0,038919 0,09038525 ! response to UV GO:0009411 104 53 1,000 0,038919 0,09029809 ! activation of phospholipase C activity GO:0007202 103 54 1,000 0,04026308 0,09332657 GO:0010863|positive regulation of phospholipase C activity, ! cell recognition GO:0008037 85 54 1,000 0,04026308 0,09323675 ! tRNA transcription GO:0009304 14 7 0,000 0,04042523 0,09352222 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,04042523 0,09343238 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,04042523 0,09334272 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,04042523 0,09325322 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,04042523 0,0931639 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,04042523 0,09307475 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,04042523 0,09298577 ! prostate gland development GO:0030850 13 7 0,000 0,04042523 0,09289696 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,04042523 0,09280831 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,04042523 0,09271984 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,04042523 0,09263154 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,04042523 0,0925434 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,04042523 0,09245543 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,04042523 0,09236763 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,04042523 0,09227999 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 0,04042523 0,09219252 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,04042523 0,09210522 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,04042523 0,09201808 ! glycolipid transport GO:0046836 10 7 0,000 0,04042523 0,09193111 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,04042523 0,0918443 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,04042523 0,09175765 ! N-terminal protein amino acid acetylation GO:0006474 13 7 0,000 0,04042523 0,09167117 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,04042523 0,09158485 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,04042523 0,09149869 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,04042523 0,0914127 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,04042523 0,09132687 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,04042523 0,09124119 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,04042523 0,09115568 ! mRNA stabilization GO:0048255 18 7 0,000 0,04042523 0,09107033 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,04042523 0,09098514 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,04042523 0,09090011 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,04042523 0,09081523 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,04042523 0,09073052 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,04042523 0,09064596 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,04042523 0,09056156 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,04042523 0,09047731 ! rhythmic behavior GO:0007622 15 7 0,000 0,04042523 0,09039323 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,04042523 0,0903093 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,04042523 0,09022552 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,04042523 0,0901419 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,04042523 0,09005844 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,04042523 0,08997513 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,04042523 0,08989197 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,04042523 0,08980897 ! mechanosensory behavior GO:0007638 14 7 0,000 0,04042523 0,08972612 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,04042523 0,08964342 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,04042523 0,08956088 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,04042523 0,08947848 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,04042523 0,08939624 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,04042523 0,08931415 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,04042523 0,08923221 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,04042523 0,08915042 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,04042523 0,08906878 ! adrenal gland development GO:0030325 17 7 0,000 0,04042523 0,08898729 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,04042523 0,08890595 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,04042523 0,08882476 ! ovulation GO:0030728 9 7 0,000 0,04042523 0,08874372 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,04042523 0,08866282 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,04042523 0,08858207 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,04042523 0,08850147 ! microtubule nucleation GO:0007020 20 7 0,000 0,04042523 0,08842101 ! proline biosynthetic process GO:0006561 10 7 0,000 0,04042523 0,0883407 ! thyroid hormone generation GO:0006590 13 7 0,000 0,04042523 0,08826054 ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,04042523 0,08818052 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,04042523 0,08810065 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,04042523 0,08802092 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,04042523 0,08794133 ! galactose metabolic process GO:0006012 13 7 0,000 0,04042523 0,08786189 ! vesicle fusion GO:0006906 17 7 0,000 0,04042523 0,08778259 ! response to dietary excess GO:0002021 8 7 0,000 0,04042523 0,08770344 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,04042523 0,08762443 ! intracellular pH reduction GO:0051452 11 7 0,000 0,04042523 0,08754556 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,04042523 0,08746683 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,04042523 0,08738824 ! organ growth GO:0035265 15 7 0,000 0,04042523 0,0873098 ! purine salvage GO:0043101 10 7 0,000 0,04042523 0,08723149 ! nucleoside transport GO:0015858 8 7 0,000 0,04042523 0,08715333 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,04042523 0,0870753 ! parturition GO:0007567 14 7 0,000 0,04042523 0,08699742 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,04042523 0,08691967 ! rRNA modification GO:0000154 14 7 0,000 0,04042523 0,08684206 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,04042523 0,0867646 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,04042523 0,08668727 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,04042523 0,08661007 ! macrophage differentiation GO:0030225 11 7 0,000 0,04042523 0,08653302 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,04042523 0,0864561 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,04042523 0,08637932 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,04042523 0,08630267 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,04042523 0,08622616 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,04042523 0,08614979 ! fibrinolysis GO:0042730 10 7 0,000 0,04042523 0,08607355 ! eating behavior GO:0042755 7 7 0,000 0,04042523 0,08599745 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,04042523 0,08592148 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,04042523 0,08584564 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,04042523 0,08576994 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,04042523 0,08569437 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,04042523 0,08561894 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,04042523 0,08554363 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,04042523 0,08546846 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,04042523 0,08539343 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,04042523 0,08531852 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,04042523 0,08524374 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,04042523 0,0851691 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,04042523 0,08509459 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,04042523 0,0850202 ! regulation of meiosis GO:0040020 12 7 0,000 0,04042523 0,08494595 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,04042523 0,08487183 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,04042523 0,08479783 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,04042523 0,08472397 ! oxygen homeostasis GO:0032364 12 7 0,000 0,04042523 0,08465023 ! transcription termination GO:0006353 13 7 0,000 0,04042523 0,08457662 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,04042523 0,08450314 ! anaphase GO:0051322 17 7 0,000 0,04042523 0,08442979 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,04042523 0,08435656 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,04042523 0,08428346 ! diuresis GO:0030146 12 7 0,000 0,04042523 0,08421049 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,04042523 0,08413764 ! thiamin metabolic process GO:0006772 7 7 0,000 0,04042523 0,08406492 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,04042523 0,08399233 ! antibiotic transport GO:0042891 9 7 0,000 0,04042523 0,08391986 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,04042523 0,08384751 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,04042523 0,08377529 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,04042523 0,08370319 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,04042523 0,08363122 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,04042523 0,08355937 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,04042523 0,08348765 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,04042523 0,08341605 ! lymph node development GO:0048535 10 7 0,000 0,04042523 0,08334457 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,04042523 0,08327321 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,04042523 0,08320198 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,04042523 0,08313087 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,04042523 0,08305987 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,04042523 0,082989 ! adult feeding behavior GO:0008343 9 7 0,000 0,04042523 0,08291825 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,04042523 0,08284763 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,04042523 0,08277712 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,04042523 0,08270673 ! embryonic heart tube development GO:0035050 10 7 0,000 0,04042523 0,08263646 ! retina homeostasis GO:0001895 12 7 0,000 0,04042523 0,08256631 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,04042523 0,08249628 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,04042523 0,08242637 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,04042523 0,08235657 ! protein prenylation GO:0018342 18 7 0,000 0,04042523 0,0822869 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,04042523 0,08221734 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,04042523 0,0821479 ! positive regulation of phospholipase activity GO:0010518 104 55 1,000 0,04162455 0,08451365 ! regulation of protein catabolic process GO:0042176 116 55 1,000 0,04162455 0,08444239 ! gastrulation GO:0007369 112 55 1,000 0,04162455 0,08437125 ! heart morphogenesis GO:0003007 97 55 1,000 0,04162455 0,08430023 ! regulation of actin filament length GO:0030832 105 56 1,000 0,04300316 0,08701901 ! skeletal muscle fiber development GO:0048741 111 56 1,000 0,04300316 0,08694589 ! nucleotide-excision repair GO:0006289 83 56 1,000 0,04300316 0,08687289 ! muscle fiber development GO:0048747 112 57 1,000 0,04439866 0,08961677 ! regulation of phospholipase activity GO:0010517 106 57 1,000 0,04439866 0,08954165 ! positive regulation of lipase activity GO:0060193 108 58 1,000 0,04581082 0,09231225 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,04606604 0,09274887 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,04606604 0,09267132 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 0,000 0,04606604 0,0925939 ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,04606604 0,09251661 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,04606604 0,09243945 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,04606604 0,09236241 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,04606604 0,09228551 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,04606604 0,09220873 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,04606604 0,09213208 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,04606604 0,09205556 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,04606604 0,09197917 ! meiotic prophase I GO:0007128 13 8 0,000 0,04606604 0,0919029 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,04606604 0,09182676 ! oligopeptide transport GO:0006857 15 8 0,000 0,04606604 0,09175074 ! UTP metabolic process GO:0046051 8 8 0,000 0,04606604 0,09167485 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,04606604 0,09159909 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,04606604 0,09152345 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,04606604 0,09144793 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,04606604 0,09137254 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,04606604 0,09129728 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,04606604 0,09122214 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,04606604 0,09114712 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,04606604 0,09107222 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,04606604 0,09099745 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,04606604 0,0909228 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,04606604 0,09084828 ! reflex GO:0060004 16 8 0,000 0,04606604 0,09077387 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,04606604 0,09069959 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,04606604 0,09062543 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,04606604 0,09055139 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,04606604 0,09047747 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,04606604 0,09040367 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,04606604 0,09032999 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,04606604 0,09025643 ! pigment granule organization GO:0048753 16 8 0,000 0,04606604 0,09018299 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,04606604 0,09010967 ! astrocyte differentiation GO:0048708 18 8 0,000 0,04606604 0,09003647 ! histidine metabolic process GO:0006547 16 8 0,000 0,04606604 0,08996339 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,04606604 0,08989043 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,04606604 0,08981758 ! glycine catabolic process GO:0006546 13 8 0,000 0,04606604 0,08974486 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,04606604 0,08967225 ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,04606604 0,08959975 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,04606604 0,08952738 ! melanin metabolic process GO:0006582 15 8 0,000 0,04606604 0,08945512 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,04606604 0,08938298 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,04606604 0,08931096 ! macrophage activation GO:0042116 12 8 0,000 0,04606604 0,08923905 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,04606604 0,08916725 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,04606604 0,08909558 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,04606604 0,08902401 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,04606604 0,08895257 ! osteoblast development GO:0002076 16 8 0,000 0,04606604 0,08888123 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,04606604 0,08881001 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,04606604 0,08873891 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,04606604 0,08866792 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,04606604 0,08859704 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,04606604 0,08852628 ! response to UV-B GO:0010224 16 8 0,000 0,04606604 0,08845562 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,04606604 0,08838509 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,04606604 0,08831466 ! intermediate filament organization GO:0045109 12 8 0,000 0,04606604 0,08824434 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,04606604 0,08817414 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,04606604 0,08810405 ! cellular extravasation GO:0045123 12 8 0,000 0,04606604 0,08803407 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,04606604 0,0879642 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,04606604 0,08789445 ! response to antibiotic GO:0046677 11 8 0,000 0,04606604 0,0878248 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,04606604 0,08775526 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,04606604 0,08768584 ! DNA topological change GO:0006265 12 8 0,000 0,04606604 0,08761652 ! response to tropane GO:0014073 15 8 0,000 0,04606604 0,08754731 GO:0042220|response to cocaine, ! melanosome transport GO:0032402 13 8 0,000 0,04606604 0,08747821 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,04606604 0,08740922 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,04606604 0,08734034 ! mast cell activation GO:0045576 14 8 0,000 0,04606604 0,08727157 ! multicellular organismal aging GO:0010259 18 8 0,000 0,04606604 0,08720291 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,04606604 0,08713435 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,04606604 0,0870659 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,04606604 0,08699756 ! nucleosome disassembly GO:0006337 14 8 0,000 0,04606604 0,08692933 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,04606604 0,0868612 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,04606604 0,08679318 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,04606604 0,08672527 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,04606604 0,08665746 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,04606604 0,08658976 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,04606604 0,08652217 ! intracellular lipid transport GO:0032365 13 8 0,000 0,04606604 0,08645468 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,04606604 0,08638729 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of macrophage activation GO:0043030 15 8 0,000 0,04606604 0,08632001 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,04606604 0,08625284 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,04606604 0,08618577 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,04606604 0,0861188 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,04606604 0,08605194 ! hormone catabolic process GO:0042447 17 8 0,000 0,04606604 0,08598518 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,04606604 0,08591852 GO:0010828|positive regulation of glucose transport, ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,04606604 0,08585197 ! ATP catabolic process GO:0006200 11 8 0,000 0,04606604 0,08578552 ! blastocyst growth GO:0001832 19 8 0,000 0,04606604 0,08571918 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,04606604 0,08565293 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,04606604 0,08558679 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,04606604 0,08552075 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,04606604 0,08545482 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,04606604 0,08538898 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,04606604 0,08532325 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,04606604 0,08525761 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,04606604 0,08519208 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,04606604 0,08512665 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,04606604 0,08506132 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,04606604 0,08499609 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,04606604 0,08493096 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,04606604 0,08486592 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,04606604 0,08480099 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,04606604 0,08473616 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,04606604 0,08467143 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,04606604 0,08460679 ! positive regulation of secretion GO:0051047 95 59 1,000 0,04723938 0,08669561 ! regulation of cellular component size GO:0032535 109 59 1,000 0,04723938 0,08662953 ! establishment of organelle localization GO:0051656 109 59 1,000 0,04723938 0,08656355 ! regulation of neurotransmitter levels GO:0001505 97 60 1,000 0,04868411 0,08914305 ! camera-type eye development GO:0043010 116 60 1,000 0,04868411 0,08907526 ! regulation of protein complex assembly GO:0043254 117 61 1,000 0,05014478 0,09167806 ! mesoderm development GO:0007498 119 61 1,000 0,05014478 0,09160845 ! ear development GO:0043583 103 62 1,000 0,05162114 0,09423404 ! viral reproductive process GO:0022415 126 62 1,000 0,05162114 0,09416259 ! axon extension GO:0048675 15 9 0,000 0,05167388 0,09418739 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,05167388 0,09411609 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,05167388 0,09404489 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,05167388 0,09397381 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,05167388 0,09390283 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,05167388 0,09383196 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,05167388 0,0937612 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,05167388 0,09369054 ! phosphate transport GO:0006817 19 9 0,000 0,05167388 0,09361999 ! reproductive behavior GO:0019098 19 9 0,000 0,05167388 0,09354955 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,05167388 0,09347921 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,05167388 0,09340898 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,05167388 0,09333885 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,05167388 0,09326883 ! GTP metabolic process GO:0046039 9 9 0,000 0,05167388 0,09319891 ! RNA methylation GO:0001510 15 9 0,000 0,05167388 0,0931291 ! elastic fiber assembly GO:0048251 15 9 0,000 0,05167388 0,09305939 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,05167388 0,09298979 ! artery development GO:0060840 24 9 0,000 0,05167388 0,09292029 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,05167388 0,0928509 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,05167388 0,0927816 ! chemosensory behavior GO:0007635 20 9 0,000 0,05167388 0,09271241 ! microtubule bundle formation GO:0001578 21 9 0,000 0,05167388 0,09264333 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,05167388 0,09257435 ! leukocyte degranulation GO:0043299 16 9 0,000 0,05167388 0,09250547 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,05167388 0,09243669 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,05167388 0,09236802 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,05167388 0,09229944 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,05167388 0,09223097 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,05167388 0,0921626 ! protein targeting to ER GO:0045047 22 9 0,000 0,05167388 0,09209433 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,05167388 0,09202616 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,05167388 0,0919581 ! T cell selection GO:0045058 23 9 0,000 0,05167388 0,09189013 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,05167388 0,09182227 ! endosome organization GO:0007032 17 9 0,000 0,05167388 0,0917545 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,05167388 0,09168684 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,05167388 0,09161927 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,05167388 0,0915518 ! mannose metabolic process GO:0006013 13 9 0,000 0,05167388 0,09148444 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,05167388 0,09141717 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,05167388 0,09135 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,05167388 0,09128293 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,05167388 0,09121596 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,05167388 0,09114908 ! ruffle organization GO:0031529 15 9 0,000 0,05167388 0,09108231 ! retinol metabolic process GO:0042572 18 9 0,000 0,05167388 0,09101563 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,05167388 0,09094905 ! behavioral fear response GO:0001662 22 9 0,000 0,05167388 0,09088256 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,05167388 0,09081618 GO:0007351|tripartite regional subdivision, ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,05167388 0,09074989 GO:0030204|chondroitin sulfate metabolic process, ! oligodendrocyte development GO:0014003 10 9 0,000 0,05167388 0,0906837 ! segment specification GO:0007379 13 9 0,000 0,05167388 0,0906176 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,05167388 0,0905516 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,05167388 0,0904857 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,05167388 0,09041989 ! response to amine stimulus GO:0014075 13 9 0,000 0,05167388 0,09035418 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,05167388 0,09028856 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,05167388 0,09022304 ! erythrocyte development GO:0048821 15 9 0,000 0,05167388 0,09015761 ! gas homeostasis GO:0033483 16 9 0,000 0,05167388 0,09009228 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,05167388 0,09002704 ! renal water homeostasis GO:0003091 14 9 0,000 0,05167388 0,0899619 ! postreplication repair GO:0006301 22 9 0,000 0,05167388 0,08989685 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,05167388 0,0898319 ! icosanoid secretion GO:0032309 15 9 0,000 0,05167388 0,08976704 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,05167388 0,08970227 ! regulation of cell division GO:0051302 15 9 0,000 0,05167388 0,0896376 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,05167388 0,08957302 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,05167388 0,08950853 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,05167388 0,08944414 ! sterol catabolic process GO:0016127 11 9 0,000 0,05167388 0,08937983 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,05167388 0,08931562 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,05167388 0,08925151 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,05167388 0,08918748 GO:0002820|negative regulation of adaptive immune response, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,05167388 0,08912355 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,05167388 0,08905971 ! musculoskeletal movement GO:0050881 14 9 0,000 0,05167388 0,08899595 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,05167388 0,0889323 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,05167388 0,08886873 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,05167388 0,08880525 ! purine base metabolic process GO:0006144 21 9 0,000 0,05167388 0,08874186 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,05167388 0,08867857 ! pigment granule transport GO:0051904 17 9 0,000 0,05167388 0,08861536 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,05167388 0,08855224 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,05167388 0,08848922 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,05167388 0,08842628 ! mitochondrion localization GO:0051646 15 9 0,000 0,05167388 0,08836343 ! cellular amino acid catabolic process GO:0009063 101 63 1,000 0,05311297 0,0907598 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 1,000 0,05462003 0,09326884 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,05724893 0,0976886 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,05724893 0,09761937 ! positive regulation of B cell proliferation GO:0030890 16 10 0,000 0,05724893 0,09755023 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,05724893 0,09748119 ! synapsis GO:0007129 13 10 0,000 0,05724893 0,09741225 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,05724893 0,09734341 ! N-glycan processing GO:0006491 20 10 0,000 0,05724893 0,09727467 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,05724893 0,09720602 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,05724893 0,09713747 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,05724893 0,09706901 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,05724893 0,09700065 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,05724893 0,09693239 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 0,05724893 0,09686423 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,05724893 0,09679615 GO:0048200|Golgi transport vesicle coating, ! androgen metabolic process GO:0008209 17 10 0,000 0,05724893 0,09672818 ! phospholipid efflux GO:0033700 16 10 0,000 0,05724893 0,0966603 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,05724893 0,09659252 ! lung alveolus development GO:0048286 26 10 0,000 0,05724893 0,09652483 ! pathogenesis GO:0009405 13 10 0,000 0,05724893 0,09645723 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,05724893 0,09638973 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,05724893 0,09632233 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,05724893 0,09625502 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,05724893 0,0961878 ! endoderm development GO:0007492 16 10 0,000 0,05724893 0,09612068 ! arginine catabolic process GO:0006527 13 10 0,000 0,05724893 0,09605365 ! proline metabolic process GO:0006560 13 10 0,000 0,05724893 0,09598671 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,05724893 0,09591987 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,05724893 0,09585312 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,05724893 0,09578646 ! V(D)J recombination GO:0033151 28 10 0,000 0,05724893 0,09571989 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,05724893 0,09565342 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,05724893 0,09558704 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,05724893 0,09552075 ! B cell proliferation GO:0042100 18 10 0,000 0,05724893 0,09545456 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,05724893 0,09538845 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,05724893 0,09532244 ! multicellular organism growth GO:0035264 18 10 0,000 0,05724893 0,09525652 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,05724893 0,09519069 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,05724893 0,09512495 ! epithelial cell development GO:0002064 20 10 0,000 0,05724893 0,0950593 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,05724893 0,09499374 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,05724893 0,09492828 ! macroautophagy GO:0016236 17 10 0,000 0,05724893 0,0948629 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,05724893 0,09479761 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,05724893 0,09473241 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,05724893 0,0946673 ! copper ion homeostasis GO:0055070 13 10 0,000 0,05724893 0,09460229 ! regulation of bone resorption GO:0045124 25 10 0,000 0,05724893 0,09453736 ! brain morphogenesis GO:0048854 23 10 0,000 0,05724893 0,09447252 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,05724893 0,09440776 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,05724893 0,0943431 ! blastoderm segmentation GO:0007350 18 10 0,000 0,05724893 0,09427853 ! DNA ligation GO:0006266 19 10 0,000 0,05724893 0,09421404 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,05724893 0,09414964 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,05724893 0,09408533 ! melanosome localization GO:0032400 16 10 0,000 0,05724893 0,09402111 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,05724893 0,09395698 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,05724893 0,09389293 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,05724893 0,09382897 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,05724893 0,0937651 ! mRNA cleavage GO:0006379 17 10 0,000 0,05724893 0,09370131 ! protein sumoylation GO:0016925 15 10 0,000 0,05724893 0,09363761 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,05724893 0,093574 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,05724893 0,09351047 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,05724893 0,09344703 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,05724893 0,09338368 ! prophase GO:0051324 15 10 0,000 0,05724893 0,09332041 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,05724893 0,09325723 ! apical protein localization GO:0045176 15 10 0,000 0,05724893 0,09319413 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,05724893 0,09313112 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! midbrain development GO:0030901 13 10 0,000 0,05724893 0,09306819 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,05724893 0,09300535 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,05724893 0,0929426 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,05724893 0,09287992 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,05724893 0,09281734 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,05724893 0,09275483 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,05724893 0,09269241 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,05724893 0,09263008 ! oocyte development GO:0048599 17 10 0,000 0,05724893 0,09256783 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,05724893 0,09250566 ! blastocyst formation GO:0001825 17 10 0,000 0,05724893 0,09244358 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,05724893 0,09238157 ! activation of innate immune response GO:0002218 12 10 0,000 0,05724893 0,09231966 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,05724893 0,09225782 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,05724893 0,09219607 ! response to nicotine GO:0035094 20 10 0,000 0,05724893 0,0921344 ! establishment of cell polarity GO:0030010 16 10 0,000 0,05724893 0,09207281 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,05724893 0,09201131 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,05724893 0,09194989 ! localization within membrane GO:0051668 20 10 0,000 0,05724893 0,09188854 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 1,000 0,05767895 0,09251704 ! cell projection assembly GO:0030031 120 66 1,000 0,05767895 0,0924554 ! chromosome segregation GO:0007059 113 67 1,000 0,05923036 0,09487899 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 1,000 0,05923036 0,09481586 ! homeostasis of number of cells GO:0048872 114 67 1,000 0,05923036 0,09475282 ! adaptive immune response GO:0002250 119 67 1,000 0,05923036 0,09468986 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! viral reproduction GO:0016032 134 68 1,000 0,0607961 0,09712843 ! regulation of lipase activity GO:0060191 130 68 1,000 0,0607961 0,09706398 ! cAMP-mediated signaling GO:0019933 120 69 1,000 0,06237595 0,09952026 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 1,000 0,06237595 0,0994543 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,06279139 0,10005039 ! respiratory burst GO:0045730 17 11 0,000 0,06279139 0,09998418 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,06279139 0,09991805 ! telencephalon cell migration GO:0022029 20 11 0,000 0,06279139 0,09985201 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,06279139 0,09978606 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,06279139 0,09972019 ! thyroid gland development GO:0030878 26 11 0,000 0,06279139 0,09965442 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 0,000 0,06279139 0,09958872 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,06279139 0,09952312 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,06279139 0,0994576 ! response to pain GO:0048265 24 11 0,000 0,06279139 0,09939217 ! T cell proliferation GO:0042098 26 11 0,000 0,06279139 0,09932682 ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,06279139 0,09926156 ! bone resorption GO:0045453 16 11 0,000 0,06279139 0,09919639 ! peptide or protein amino-terminal blocking GO:0018409 21 11 0,000 0,06279139 0,0991313 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,06279139 0,09906629 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,06279139 0,09900137 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,06279139 0,09893654 ! melanocyte differentiation GO:0030318 21 11 0,000 0,06279139 0,09887179 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,06279139 0,09880713 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,06279139 0,09874255 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,06279139 0,09867805 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,06279139 0,09861364 GO:0043088|regulation of Cdc42 GTPase activity, ! lipid digestion GO:0044241 18 11 0,000 0,06279139 0,09854931 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,06279139 0,09848507 ! UV protection GO:0009650 19 11 0,000 0,06279139 0,09842091 ! adult heart development GO:0007512 14 11 0,000 0,06279139 0,09835683 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,06279139 0,09829284 ! temperature homeostasis GO:0001659 17 11 0,000 0,06279139 0,09822893 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,06279139 0,0981651 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,06279139 0,09810136 ! regulation of organ growth GO:0046620 13 11 0,000 0,06279139 0,0980377 ! pigment granule localization GO:0051875 20 11 0,000 0,06279139 0,09797412 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,06279139 0,09791063 ! vasoconstriction GO:0042310 18 11 0,000 0,06279139 0,09784721 ! embryonic axis specification GO:0000578 18 11 0,000 0,06279139 0,09778388 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,06279139 0,09772063 ! snRNA metabolic process GO:0016073 24 11 0,000 0,06279139 0,09765746 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,06279139 0,09759438 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,06279139 0,09753137 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,06279139 0,09746845 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,06279139 0,09740561 ! zymogen activation GO:0031638 15 11 0,000 0,06279139 0,09734284 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,06279139 0,09728016 ! nucleosome positioning GO:0016584 15 11 0,000 0,06279139 0,09721756 ! regulation of isotype switching GO:0045191 22 11 0,000 0,06279139 0,09715504 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,06279139 0,09709261 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,06279139 0,09703025 ! acid secretion GO:0046717 18 11 0,000 0,06279139 0,09696797 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,06279139 0,09690577 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,06279139 0,09684365 ! oocyte differentiation GO:0009994 18 11 0,000 0,06279139 0,09678161 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,06279139 0,09671965 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! cholesterol efflux GO:0033344 19 11 0,000 0,06279139 0,09665777 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,06279139 0,09659597 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,06279139 0,09653425 ! germ cell migration GO:0008354 25 11 0,000 0,06279139 0,0964726 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,06279139 0,09641104 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,06279139 0,09634955 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,06279139 0,09628814 ! defense response to fungus GO:0050832 13 11 0,000 0,06279139 0,09622681 ! developmental induction GO:0031128 19 11 0,000 0,06279139 0,09616556 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,06279139 0,09610439 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,06279139 0,09604329 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,06279139 0,09598227 ! sequestering of metal ion GO:0051238 14 11 0,000 0,06279139 0,09592133 ! nucleus localization GO:0051647 19 11 0,000 0,06279139 0,09586047 ! regulation of synapse organization GO:0050807 17 11 0,000 0,06279139 0,09579968 ! humoral immune response GO:0006959 109 71 1,000 0,06557714 0,09998644 ! B cell activation GO:0042113 160 71 1,000 0,06557714 0,09992311 ! regulation of MAPKKK cascade GO:0043408 142 71 1,000 0,06557714 0,09985987 ! regulation of immune effector process GO:0002697 137 71 1,000 0,06557714 0,09979671 ! amine catabolic process GO:0009310 117 71 1,000 0,06557714 0,09973363 ! acute inflammatory response GO:0002526 113 72 1,000 0,06719804 0,10213423 ! carbohydrate transport GO:0008643 110 72 1,000 0,06719804 0,10206975 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 1,000 0,06719804 0,10200535 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,06830146 0,10361495 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,06830146 0,10354966 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,06830146 0,10348445 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,06830146 0,10341932 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,06830146 0,10335428 ! cartilage condensation GO:0001502 20 12 0,000 0,06830146 0,10328932 ! mating GO:0007618 17 12 0,000 0,06830146 0,10322444 ! protein complex disassembly GO:0043241 27 12 0,000 0,06830146 0,10315964 GO:0043624|cellular protein complex disassembly, ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,06830146 0,10309492 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,06830146 0,10303028 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,06830146 0,10296573 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,06830146 0,10290125 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,06830146 0,10283686 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,06830146 0,10277255 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,06830146 0,10270831 ! drug transport GO:0015893 16 12 0,000 0,06830146 0,10264416 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,06830146 0,10258009 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,06830146 0,1025161 ! polyamine metabolic process GO:0006595 17 12 0,000 0,06830146 0,10245218 ! mitotic spindle organization GO:0007052 21 12 0,000 0,06830146 0,10238835 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,06830146 0,1023246 ! forebrain cell migration GO:0021885 21 12 0,000 0,06830146 0,10226092 ! asymmetric protein localization GO:0008105 20 12 0,000 0,06830146 0,10219733 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,06830146 0,10213381 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,06830146 0,10207037 ! entry into host cell GO:0030260 32 12 0,000 0,06830146 0,10200702 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,06830146 0,10194374 ! monoamine transport GO:0015844 18 12 0,000 0,06830146 0,10188054 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,06830146 0,10181741 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,06830146 0,10175437 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,06830146 0,1016914 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,06830146 0,10162851 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,06830146 0,1015657 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,06830146 0,10150297 ! protein homotetramerization GO:0051289 21 12 0,000 0,06830146 0,10144031 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,06830146 0,10137773 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,06830146 0,10131523 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,06830146 0,10125281 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,06830146 0,10119046 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,06830146 0,10112819 ! fucose catabolic process GO:0019317 22 12 0,000 0,06830146 0,10106599 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,06830146 0,10100387 ! histone acetylation GO:0016573 26 12 0,000 0,06830146 0,10094183 ! histone methylation GO:0016571 26 12 0,000 0,06830146 0,10087987 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,06830146 0,10081798 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,06830146 0,10075616 ! T cell homeostasis GO:0043029 25 12 0,000 0,06830146 0,10069443 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,06830146 0,10063276 ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,06830146 0,10057118 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,06830146 0,10050967 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,06830146 0,10044823 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,06830146 0,10038687 ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,06830146 0,10032558 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,06830146 0,10026437 ! response to cold GO:0009409 17 12 0,000 0,06830146 0,10020323 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,06830146 0,10014217 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,06830146 0,10008118 ! learning or memory GO:0007611 147 73 1,000 0,0688322 0,10079748 ! neurotransmitter transport GO:0006836 123 74 1,000 0,0704794 0,10314686 ! regulation of actin cytoskeleton organization GO:0032956 149 74 1,000 0,0704794 0,10308415 ! leukocyte mediated immunity GO:0002443 128 74 1,000 0,0704794 0,10302153 ! eye development GO:0001654 143 74 1,000 0,0704794 0,10295898 ! organelle localization GO:0051640 136 74 1,000 0,0704794 0,1028965 ! cell-matrix adhesion GO:0007160 163 75 1,000 0,07213944 0,10525621 ! regulation of vesicle-mediated transport GO:0060627 119 75 1,000 0,07213944 0,10519242 ! cGMP metabolic process GO:0046068 18 13 0,000 0,07377931 0,10751848 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,07377931 0,10745339 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,07377931 0,10738839 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,07377931 0,10732346 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,07377931 0,10725862 ! organelle fusion GO:0048284 32 13 0,000 0,07377931 0,10719385 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,07377931 0,10712915 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,07377931 0,10706454 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,07377931 0,107 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,07377931 0,10693555 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,07377931 0,10687117 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,07377931 0,10680686 ! methionine metabolic process GO:0006555 27 13 0,000 0,07377931 0,10674264 ! plasma membrane organization GO:0007009 24 13 0,000 0,07377931 0,10667849 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,07377931 0,10661442 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,07377931 0,10655042 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,07377931 0,10648651 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,07377931 0,10642267 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,07377931 0,1063589 ! cytokine metabolic process GO:0042107 22 13 0,000 0,07377931 0,10629521 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,07377931 0,1062316 ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,07377931 0,10616807 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,07377931 0,10610461 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,07377931 0,10604122 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,07377931 0,10597792 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,07377931 0,10591468 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,07377931 0,10585153 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,07377931 0,10578844 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,07377931 0,10572544 ! ribosome assembly GO:0042255 17 13 0,000 0,07377931 0,1056625 ! regulation of monooxygenase activity GO:0032768 33 13 0,000 0,07377931 0,10559965 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,07377931 0,10553687 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,07377931 0,10547416 ! chromatin silencing GO:0006342 26 13 0,000 0,07377931 0,10541152 ! regulation of epidermis development GO:0045682 19 13 0,000 0,07377931 0,10534897 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,07377931 0,10528648 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,07377931 0,10522407 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,07377931 0,10516173 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,07377931 0,10509947 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,07377931 0,10503728 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,07377931 0,10497517 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,07377931 0,10491313 ! embryonic placenta development GO:0001892 23 13 0,000 0,07377931 0,10485116 ! insulin secretion GO:0030073 23 13 0,000 0,07377931 0,10478926 ! actin filament polymerization GO:0030041 24 13 0,000 0,07377931 0,10472744 ! acrosome reaction GO:0007340 18 13 0,000 0,07377931 0,10466569 ! development of primary sexual characteristics GO:0045137 124 76 1,000 0,07381211 0,10465052 ! defense response to bacterium GO:0042742 89 76 1,000 0,07381211 0,10458889 ! regulation of actin filament-based process GO:0032970 152 77 1,000 0,07549721 0,10691365 ! positive regulation of ligase activity GO:0051351 124 77 1,000 0,07549721 0,10685076 ! blood coagulation GO:0007596 146 78 1,000 0,07719454 0,10918875 GO:0050817|coagulation, ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 1,000 0,07890389 0,11154099 ! activation of protein kinase activity GO:0032147 147 79 1,000 0,07890389 0,11147549 ! rRNA transcription GO:0009303 25 14 0,000 0,07922513 0,11186365 ! lactation GO:0007595 26 14 0,000 0,07922513 0,11179804 ! N-terminal protein amino acid modification GO:0031365 27 14 0,000 0,07922513 0,11173251 ! reproductive cellular process GO:0048610 20 14 0,000 0,07922513 0,11166705 ! tRNA modification GO:0006400 20 14 0,000 0,07922513 0,11160167 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,07922513 0,11153637 ! regulation of S phase GO:0033261 23 14 0,000 0,07922513 0,11147115 ! water transport GO:0006833 21 14 0,000 0,07922513 0,111406 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,07922513 0,11134092 ! non-recombinational repair GO:0000726 25 14 0,000 0,07922513 0,11127592 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,07922513 0,111211 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,07922513 0,11114616 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,07922513 0,11108139 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,07922513 0,11101669 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,07922513 0,11095207 ! palate development GO:0060021 31 14 0,000 0,07922513 0,11088753 ! regulated secretory pathway GO:0045055 23 14 0,000 0,07922513 0,11082306 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,07922513 0,11075866 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,07922513 0,11069434 ! arginine metabolic process GO:0006525 17 14 0,000 0,07922513 0,1106301 ! regulation of heart rate GO:0002027 24 14 0,000 0,07922513 0,11056593 ! organic alcohol transport GO:0015850 29 14 0,000 0,07922513 0,11050183 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,07922513 0,11043781 ! embryo implantation GO:0007566 30 14 0,000 0,07922513 0,11037386 ! neutral amino acid transport GO:0015804 26 14 0,000 0,07922513 0,11030999 ! L-amino acid transport GO:0015807 30 14 0,000 0,07922513 0,11024619 ! bone mineralization GO:0030282 17 14 0,000 0,07922513 0,11018246 ! stem cell development GO:0048864 43 14 0,000 0,07922513 0,11011881 GO:0019827|stem cell maintenance, ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,07922513 0,11005523 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,07922513 0,10999172 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,07922513 0,10992829 ! cofactor transport GO:0051181 26 14 0,000 0,07922513 0,10986493 ! NADP metabolic process GO:0006739 24 14 0,000 0,07922513 0,10980165 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,07922513 0,10973843 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,07922513 0,10967529 ! intestinal absorption GO:0050892 25 14 0,000 0,07922513 0,10961222 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,07922513 0,10954923 ! oxygen transport GO:0015671 21 14 0,000 0,07922513 0,10948631 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,07922513 0,10942346 ! regulation of RNA stability GO:0043487 32 14 0,000 0,07922513 0,10936068 ! regulation of axon extension GO:0030516 37 14 0,000 0,07922513 0,10929797 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,07922513 0,10923533 ! cell-substrate adhesion GO:0031589 171 81 1,000 0,08235789 0,11348974 ! response to drug GO:0042493 143 82 1,000 0,08410214 0,11582699 ! response to nutrient GO:0007584 125 82 1,000 0,08410214 0,11576073 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,08463911 0,11643322 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,08463911 0,11636669 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,08463911 0,11630023 ! superoxide anion generation GO:0042554 20 15 0,000 0,08463911 0,11623385 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,08463911 0,11616754 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,08463911 0,11610131 ! copper ion transport GO:0006825 20 15 0,000 0,08463911 0,11603516 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,08463911 0,11596908 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,08463911 0,11590308 ! response to cAMP GO:0051591 22 15 0,000 0,08463911 0,11583715 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,08463911 0,11577129 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,08463911 0,11570551 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,08463911 0,11563981 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,08463911 0,11557418 ! response to hexose stimulus GO:0009746 22 15 0,000 0,08463911 0,11550862 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,08463911 0,11544314 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,08463911 0,11537774 ! vesicle coating GO:0006901 33 15 0,000 0,08463911 0,1153124 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,08463911 0,11524714 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,08463911 0,11518196 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,08463911 0,11511685 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,08463911 0,11505181 ! regulation of vasodilation GO:0042312 26 15 0,000 0,08463911 0,11498685 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,08463911 0,11492195 ! histone deacetylation GO:0016575 20 15 0,000 0,08463911 0,11485714 ! mRNA splice site selection GO:0006376 38 15 0,000 0,08463911 0,11479239 ! tissue regeneration GO:0042246 26 15 0,000 0,08463911 0,11472772 ! water homeostasis GO:0030104 27 15 0,000 0,08463911 0,11466312 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,08463911 0,1145986 ! muscle maintenance GO:0046716 26 15 0,000 0,08463911 0,11453414 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,08463911 0,11446976 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,08463911 0,11440545 ! dopamine metabolic process GO:0042417 35 15 0,000 0,08463911 0,11434121 ! heme biosynthetic process GO:0006783 29 15 0,000 0,08463911 0,11427705 ! cell killing GO:0001906 29 15 0,000 0,08463911 0,11421296 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,08463911 0,11414894 ! detection of bacterium GO:0016045 18 15 0,000 0,08463911 0,11408499 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,08463911 0,11402111 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,08463911 0,1139573 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,08463911 0,11389357 ! peptide hormone processing GO:0016486 23 15 0,000 0,08463911 0,11382991 ! hemostasis GO:0007599 158 84 1,000 0,08762419 0,11777867 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,09002144 0,12093333 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,09002144 0,12086584 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,09002144 0,12079843 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,09002144 0,1207311 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,09002144 0,12066384 ! filopodium assembly GO:0046847 32 16 0,000 0,09002144 0,12059665 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,09002144 0,12052954 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,09002144 0,12046251 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,09002144 0,12039555 ! startle response GO:0001964 28 16 0,000 0,09002144 0,12032866 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,09002144 0,12026185 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,09002144 0,12019511 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,09002144 0,12012845 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,09002144 0,12006186 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,09002144 0,11999534 ! protein polyubiquitination GO:0000209 34 16 0,000 0,09002144 0,1199289 ! glutamate metabolic process GO:0006536 22 16 0,000 0,09002144 0,11986253 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,09002144 0,11979623 ! response to osmotic stress GO:0006970 25 16 0,000 0,09002144 0,11973001 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,09002144 0,11966386 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,09002144 0,11959778 ! fructose metabolic process GO:0006000 25 16 0,000 0,09002144 0,11953178 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,09002144 0,11946585 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,09002144 0,11939999 ! intermediate filament-based process GO:0045103 32 16 0,000 0,09002144 0,11933421 ! negative regulation of immune response GO:0050777 35 16 0,000 0,09002144 0,1192685 ! axon cargo transport GO:0008088 43 16 0,000 0,09002144 0,11920286 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,09002144 0,11913729 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,09002144 0,11907179 ! DNA replication initiation GO:0006270 27 16 0,000 0,09002144 0,11900637 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,09002144 0,11894101 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,09002144 0,11887573 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,09002144 0,11881053 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,09002144 0,11874539 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,09002144 0,11868032 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,09002144 0,11861533 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,09002144 0,1185504 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,09002144 0,11848555 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,09002144 0,11842077 ! nitrogen compound catabolic process GO:0044270 143 87 1,000 0,0929883 0,12225675 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,0953723 0,12532264 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,0953723 0,12525423 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,0953723 0,1251859 ! inositol metabolic process GO:0006020 28 17 0,000 0,0953723 0,12511764 ! gene silencing by RNA GO:0031047 36 17 0,000 0,0953723 0,12504946 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,0953723 0,12498135 ! glial cell development GO:0021782 27 17 0,000 0,0953723 0,12491331 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,0953723 0,12484535 ! adult walking behavior GO:0007628 33 17 0,000 0,0953723 0,12477746 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,0953723 0,12470965 ! heart looping GO:0001947 30 17 0,000 0,0953723 0,12464191 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,0953723 0,12457424 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,0953723 0,12450665 ! myoblast differentiation GO:0045445 45 17 0,000 0,0953723 0,12443913 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,0953723 0,12437168 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,0953723 0,12430431 ! glycine metabolic process GO:0006544 28 17 0,000 0,0953723 0,12423701 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,0953723 0,12416978 ! NAD metabolic process GO:0019674 29 17 0,000 0,0953723 0,12410263 ! membrane budding GO:0006900 37 17 0,000 0,0953723 0,12403554 ! DNA integration GO:0015074 29 17 0,000 0,0953723 0,12396853 ! regulation of protein binding GO:0043393 33 17 0,000 0,0953723 0,1239016 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,0953723 0,12383473 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,0953723 0,12376794 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,0953723 0,12370122 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,0953723 0,12363457 GO:0002712|regulation of B cell mediated immunity, ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,0953723 0,12356799 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,0953723 0,12350148 ! steroid catabolic process GO:0006706 31 17 0,000 0,0953723 0,12343505 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,0953723 0,12336869 ! gas transport GO:0015669 25 17 0,000 0,0953723 0,12330239 ! organic cation transport GO:0015695 31 17 0,000 0,0953723 0,12323617 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,0953723 0,12317002 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,0953723 0,12310395 ! microspike assembly GO:0030035 36 17 0,000 0,0953723 0,12303794 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,0953723 0,122972 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,0953723 0,12290614 ! sex differentiation GO:0007548 145 90 1,000 0,09844522 0,12679829 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,10069187 0,1296226 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,10069187 0,12955329 ! phosphoinositide phosphorylation GO:0046854 33 18 0,000 0,10069187 0,12948404 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,10069187 0,12941487 ! memory GO:0007613 31 18 0,000 0,10069187 0,12934578 ! negative regulation of ion transport GO:0043271 24 18 0,000 0,10069187 0,12927676 ! patterning of blood vessels GO:0001569 39 18 0,000 0,10069187 0,12920781 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,10069187 0,12913894 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,10069187 0,12907014 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,10069187 0,12900141 ! glutamine metabolic process GO:0006541 29 18 0,000 0,10069187 0,12893275 ! response to retinoic acid GO:0032526 26 18 0,000 0,10069187 0,12886417 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,10069187 0,12879566 ! response to fungus GO:0009620 21 18 0,000 0,10069187 0,12872723 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,10069187 0,12865887 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,10069187 0,12859058 ! vitamin transport GO:0051180 27 18 0,000 0,10069187 0,12852236 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,10069187 0,12845421 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,10069187 0,12838614 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,10069187 0,12831814 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,10069187 0,12825021 ! regulation of membrane potential GO:0042391 164 93 1,000 0,10399009 0,13238104 ! transcription initiation GO:0006352 153 94 1,000 0,1058571 0,13468651 ! protein secretion GO:0009306 39 19 0,000 0,10598034 0,13477204 ! negative regulation of defense response GO:0031348 25 19 0,000 0,10598034 0,13470084 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,10598034 0,13462972 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,10598034 0,13455868 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,10598034 0,13448771 ! lipid phosphorylation GO:0046834 35 19 0,000 0,10598034 0,13441681 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,10598034 0,13434599 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,10598034 0,13427525 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,10598034 0,13420458 ! bile acid metabolic process GO:0008206 29 19 0,000 0,10598034 0,13413398 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,10598034 0,13406346 ! cerebral cortex development GO:0021987 36 19 0,000 0,10598034 0,13399301 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,10598034 0,13392263 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,10598034 0,13385233 ! heme metabolic process GO:0042168 36 19 0,000 0,10598034 0,13378211 ! plasma membrane fusion GO:0045026 28 19 0,000 0,10598034 0,13371195 ! peptide cross-linking GO:0018149 37 19 0,000 0,10598034 0,13364187 ! protein export from nucleus GO:0006611 36 19 0,000 0,10598034 0,13357187 ! heart process GO:0003015 30 19 0,000 0,10598034 0,13350193 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,10598034 0,13343207 GO:0006692|prostanoid metabolic process, ! visual learning GO:0008542 36 19 0,000 0,10598034 0,13336229 ! cellular pigmentation GO:0033059 36 19 0,000 0,10598034 0,13329257 ! G1 phase GO:0051318 40 19 0,000 0,10598034 0,13322293 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,10598034 0,13315336 ! cell-cell junction organization GO:0045216 35 19 0,000 0,10598034 0,13308387 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,10598034 0,13301445 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,10598034 0,1329451 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,10598034 0,13287582 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,10598034 0,13280661 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,10598034 0,13273748 ! cilium assembly GO:0042384 37 19 0,000 0,10598034 0,13266841 ! mRNA transport GO:0051028 169 96 1,000 0,10961819 0,137151 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,11123788 0,13910516 ! positive regulation of ossification GO:0045778 47 20 0,000 0,11123788 0,1390329 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,11123788 0,13896072 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,11123788 0,1388886 ! protein amino acid acetylation GO:0006473 39 20 0,000 0,11123788 0,13881657 ! cAMP metabolic process GO:0046058 36 20 0,000 0,11123788 0,1387446 ! response to vitamin GO:0033273 31 20 0,000 0,11123788 0,13867271 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,11123788 0,1386009 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,11123788 0,13852916 ! retinoid metabolic process GO:0001523 32 20 0,000 0,11123788 0,13845749 GO:0016101|diterpenoid metabolic process, ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,11123788 0,1383859 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,11123788 0,13831439 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,11123788 0,13824294 GO:0032392|DNA geometric change, ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,11123788 0,13817157 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,11123788 0,13810028 ! body fluid secretion GO:0007589 31 20 0,000 0,11123788 0,13802905 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,11123788 0,13795791 ! stem cell differentiation GO:0048863 53 20 0,000 0,11123788 0,13788683 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,11123788 0,13781583 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,11123788 0,1377449 ! sensory perception of pain GO:0019233 30 20 0,000 0,11123788 0,13767404 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,11123788 0,13760326 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,11123788 0,13753255 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,11123788 0,13746191 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,11123788 0,13739134 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,11123788 0,13732085 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,11123788 0,13725043 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,11123788 0,13718008 ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,11123788 0,1371098 ! actin filament-based movement GO:0030048 43 20 0,000 0,11123788 0,1370396 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,11123788 0,13696947 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,11123788 0,13689941 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,11123788 0,13682942 ! response to virus GO:0009615 160 98 1,000 0,11341423 0,13943518 ! carboxylic acid catabolic process GO:0046395 156 98 1,000 0,11341423 0,13936397 GO:0016054|organic acid catabolic process, ! skeletal muscle tissue development GO:0007519 186 99 1,000 0,11532495 0,14163952 GO:0060538|skeletal muscle organ development, ! regulation of cell killing GO:0031341 42 21 0,000 0,11646468 0,14296633 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,11646468 0,14289343 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,11646468 0,1428206 ! glycerol metabolic process GO:0006071 34 21 0,000 0,11646468 0,14274784 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,11646468 0,14267516 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,11646468 0,14260255 ! axis specification GO:0009798 38 21 0,000 0,11646468 0,14253002 ! ovarian follicle development GO:0001541 35 21 0,000 0,11646468 0,14245755 ! smooth muscle contraction GO:0006939 46 21 0,000 0,11646468 0,14238517 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,11646468 0,14231285 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,11646468 0,14224061 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,11646468 0,14216845 ! cytolysis GO:0019835 24 21 0,000 0,11646468 0,14209635 ! vasodilation GO:0042311 39 21 0,000 0,11646468 0,14202433 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,11646468 0,14195239 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,11646468 0,14188051 ! oogenesis GO:0048477 36 21 0,000 0,11646468 0,14180871 ! DNA modification GO:0006304 34 21 0,000 0,11646468 0,14173698 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,11646468 0,14166532 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,11646468 0,14159374 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,11646468 0,14152223 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,11646468 0,14145079 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,11646468 0,14137942 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,11646468 0,14130812 ! collagen catabolic process GO:0030574 28 21 0,000 0,11646468 0,1412369 ! sperm-egg recognition GO:0035036 21 21 0,000 0,11646468 0,14116575 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,12166091 0,1473898 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,12166091 0,14731562 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,12166091 0,14724152 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,12166091 0,14716749 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,12166091 0,14709354 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,12166091 0,14701966 ! regeneration GO:0031099 41 22 0,000 0,12166091 0,14694585 ! keratinization GO:0031424 28 22 0,000 0,12166091 0,14687212 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,12166091 0,14679847 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,12166091 0,14672488 ! sensory perception of taste GO:0050909 28 22 0,000 0,12166091 0,14665137 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,12166091 0,14657794 ! vacuolar transport GO:0007034 36 22 0,000 0,12166091 0,14650457 ! lysosome organization GO:0007040 41 22 0,000 0,12166091 0,14643129 ! central nervous system neuron development GO:0021954 46 22 0,000 0,12166091 0,14635807 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,12166091 0,14628493 ! fucose metabolic process GO:0006004 39 22 0,000 0,12166091 0,14621186 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,12166091 0,14613886 GO:0060415|muscle tissue morphogenesis, ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,12166091 0,14606594 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,12166091 0,14599309 ! sarcomere organization GO:0045214 30 22 0,000 0,12166091 0,14592031 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,12166091 0,1458476 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,12166091 0,14577497 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,12166091 0,14570241 ! gluconeogenesis GO:0006094 33 23 0,000 0,12682675 0,15181351 ! viral genome replication GO:0019079 41 23 0,000 0,12682675 0,15173802 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,12682675 0,1516626 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,12682675 0,15158726 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,12682675 0,15151199 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,12682675 0,1514368 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,12682675 0,15136168 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,12682675 0,15128664 ! visual behavior GO:0007632 42 23 0,000 0,12682675 0,15121167 ! regulation of DNA recombination GO:0000018 48 23 0,000 0,12682675 0,15113678 ! response to ethanol GO:0045471 46 23 0,000 0,12682675 0,15106196 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,12682675 0,15098721 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! peroxisome organization GO:0007031 37 23 0,000 0,12682675 0,15091254 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,12682675 0,15083794 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,12682675 0,15076342 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,12682675 0,15068897 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,12682675 0,15061459 GO:0051693|actin filament capping, ! regulation of viral reproduction GO:0050792 38 23 0,000 0,12682675 0,15054028 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,12682675 0,15046605 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,12682675 0,1503919 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,12682675 0,15031781 ! cell-cell recognition GO:0009988 25 23 0,000 0,12682675 0,1502438 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,12682675 0,15016986 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,12682675 0,15009599 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,12682675 0,1500222 GO:0006099|tricarboxylic acid cycle, ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,13196238 0,15602039 GO:0016444|somatic cell DNA recombination, ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,13196238 0,15594375 ! vacuole organization GO:0007033 43 24 0,000 0,13196238 0,1558672 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,13196238 0,15579072 ! digestive system process GO:0022600 39 24 0,000 0,13196238 0,15571431 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,13196238 0,15563798 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,13196238 0,15556173 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,13196238 0,15548555 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,13196238 0,15540944 ! membrane depolarization GO:0051899 39 24 0,000 0,13196238 0,15533341 ! pentose metabolic process GO:0019321 35 24 0,000 0,13196238 0,15525745 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,13196238 0,15518157 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,13196238 0,15510576 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,13196238 0,15503002 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,13196238 0,15495436 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,13196238 0,15487877 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,13196238 0,15480326 ! regulation of amine transport GO:0051952 40 24 0,000 0,13196238 0,15472782 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 0,000 0,13706797 0,16063592 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,13706797 0,16055771 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,13706797 0,16047958 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 0,000 0,13706797 0,16040153 ! sperm motility GO:0030317 31 25 0,000 0,13706797 0,16032355 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,13706797 0,16024565 ! chromosome condensation GO:0030261 45 25 0,000 0,13706797 0,16016782 ! coenzyme catabolic process GO:0009109 39 25 0,000 0,13706797 0,16009007 ! regulation of insulin secretion GO:0050796 37 25 0,000 0,13706797 0,16001239 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,13706797 0,15993479 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,13706797 0,15985727 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,13706797 0,15977982 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 0,000 0,13706797 0,15970244 ! immunoglobulin production GO:0002377 55 25 0,000 0,13706797 0,15962514 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,13706797 0,15954792 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,13706797 0,15947077 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,13706797 0,15939369 ! telomere organization GO:0032200 43 25 0,000 0,13706797 0,15931669 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,13706797 0,15923976 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,13706797 0,15916291 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,14214371 0,16497721 ! embryonic pattern specification GO:0009880 44 26 0,000 0,14214371 0,16489767 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,14214371 0,1648182 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,14214371 0,1647388 ! initiation of viral infection GO:0019059 57 26 0,000 0,14214371 0,16465949 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,14214371 0,16458025 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,14214371 0,16450109 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,14214371 0,164422 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,14214371 0,16434299 ! molting cycle process GO:0022404 50 26 0,000 0,14214371 0,16426405 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,14214371 0,16418519 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,14214371 0,16410641 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,14214371 0,1640277 GO:0051297|centrosome organization, ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,14214371 0,16394907 ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,14214371 0,16387051 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,14214371 0,16379203 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,14214371 0,16371362 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,14214371 0,16363529 ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,14214371 0,16355703 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,14214371 0,16347885 ! blastocyst development GO:0001824 49 26 0,000 0,14214371 0,16340074 ! leukocyte proliferation GO:0070661 52 26 0,000 0,14214371 0,16332271 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,14214371 0,16324475 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,14214371 0,16316687 ! iron ion transport GO:0006826 59 27 0,000 0,14718975 0,16887866 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,14718975 0,16879816 ! protein amino acid acylation GO:0043543 55 27 0,000 0,14718975 0,16871774 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,14718975 0,1686374 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,14718975 0,16855714 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,14718975 0,16847695 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,14718975 0,16839684 ! autophagy GO:0006914 41 27 0,000 0,14718975 0,1683168 ! male gonad development GO:0008584 44 27 0,000 0,14718975 0,16823684 ! response to toxin GO:0009636 47 27 0,000 0,14718975 0,16815695 ! primary neural tube formation GO:0014020 51 27 0,000 0,14718975 0,16807715 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,14718975 0,16799741 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,14718975 0,16791775 ! glutathione metabolic process GO:0006749 39 27 0,000 0,14718975 0,16783817 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,14718975 0,16775867 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,14718975 0,16767924 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,15220628 0,17331203 ! circadian rhythm GO:0007623 50 28 0,000 0,15220628 0,17323005 ! dendrite development GO:0016358 59 28 0,000 0,15220628 0,17314814 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,15220628 0,17306631 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,15220628 0,17298456 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,15220628 0,17290289 ! synaptogenesis GO:0007416 42 28 0,000 0,15220628 0,17282129 ! lipid oxidation GO:0034440 43 28 0,000 0,15220628 0,17273977 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,15220628 0,17265833 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,15220628 0,17257696 ! translational initiation GO:0006413 65 29 0,000 0,15719347 0,17814766 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,15719347 0,17806379 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,15719347 0,17798 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,15719347 0,17789628 ! catechol metabolic process GO:0009712 54 29 0,000 0,15719347 0,17781264 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,15719347 0,17772908 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,15719347 0,1776456 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,15719347 0,1775622 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,15719347 0,17747888 GO:0002764|immune response-regulating signal transduction, ! cell fate determination GO:0001709 60 29 0,000 0,15719347 0,17739563 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,15719347 0,17731247 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,15719347 0,17722938 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,15719347 0,17714637 ! tissue homeostasis GO:0001894 48 29 0,000 0,15719347 0,17706343 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,15719347 0,17698058 ! phenol metabolic process GO:0018958 55 30 0,000 0,16215149 0,1824773 ! zinc ion transport GO:0006829 45 30 0,000 0,16215149 0,18239199 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,16215149 0,18230676 ! regulation of innate immune response GO:0045088 51 30 0,000 0,16215149 0,18222161 ! myofibril assembly GO:0030239 47 30 0,000 0,16215149 0,18213654 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,16215149 0,18205155 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,16215149 0,18196664 ! phospholipid transport GO:0015914 51 30 0,000 0,16215149 0,18188181 ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,16215149 0,18179705 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,16215149 0,18171238 ! response to heat GO:0009408 50 30 0,000 0,16215149 0,18162778 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,1670805 0,18706174 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,1670805 0,18697473 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,1670805 0,18688781 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,1670805 0,18680097 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,1670805 0,1867142 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,1670805 0,18662752 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,1670805 0,18654092 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,1670805 0,1864544 ! ovulation cycle process GO:0022602 49 31 0,000 0,1670805 0,18636795 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,1670805 0,18628159 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,1670805 0,18619531 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,1670805 0,18610911 ! natural killer cell activation GO:0030101 45 31 0,000 0,1670805 0,18602299 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,1670805 0,18593695 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,1670805 0,18585098 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,1670805 0,1857651 ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,1670805 0,1856793 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,17198068 0,19103671 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,17198068 0,19094855 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,17198068 0,19086047 ! cholesterol transport GO:0030301 56 32 0,000 0,17198068 0,19077248 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,17198068 0,19068457 ! spliceosome assembly GO:0000245 67 32 0,000 0,17198068 0,19059673 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,17198068 0,19050898 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,17198068 0,19042131 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,17198068 0,19033372 ! muscle cell development GO:0055001 49 32 0,000 0,17198068 0,19024621 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,17198068 0,19015878 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,17198068 0,19007143 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,17198068 0,18998416 ! ovulation cycle GO:0042698 51 32 0,000 0,17198068 0,18989697 ! BMP signaling pathway GO:0030509 64 32 0,000 0,17198068 0,18980987 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,17198068 0,18972284 ! gene silencing GO:0016458 65 32 0,000 0,17198068 0,18963589 ! post-embryonic development GO:0009791 69 33 0,000 0,17685219 0,19491817 ! protein targeting to membrane GO:0006612 68 33 0,000 0,17685219 0,19482892 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,17685219 0,19473975 ! ceramide metabolic process GO:0006672 64 33 0,000 0,17685219 0,19465067 ! sterol transport GO:0015918 57 33 0,000 0,17685219 0,19456167 ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,17685219 0,19447274 ! adult locomotory behavior GO:0008344 59 33 0,000 0,17685219 0,1943839 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,17685219 0,19429514 ! glial cell differentiation GO:0010001 63 34 0,000 0,1816952 0,19952471 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,1816952 0,19943369 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,1816952 0,19934275 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,1816952 0,19925189 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,1816952 0,19916112 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,1816952 0,19907042 ! spermatid development GO:0007286 63 34 0,000 0,1816952 0,19897981 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,1816952 0,19888929 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,1816952 0,19879884 ! regulation of muscle development GO:0048634 70 35 0,000 0,18650988 0,20397398 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,18650988 0,20388131 ! female gonad development GO:0008585 58 35 0,000 0,18650988 0,20378872 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,18650988 0,20369622 GO:0006639|acylglycerol metabolic process, ! cytokine production GO:0001816 59 35 0,000 0,18650988 0,20360379 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,18650988 0,20351146 ! vesicle localization GO:0051648 64 35 0,000 0,18650988 0,2034192 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,19129639 0,20854513 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,19129639 0,20845068 ! positive regulation of cell development GO:0010720 80 36 0,000 0,19129639 0,20835632 ! regulation of proteolysis GO:0030162 72 36 0,000 0,19129639 0,20826204 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,19129639 0,20816784 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,19129639 0,20807374 ! aerobic respiration GO:0009060 55 36 0,000 0,19129639 0,20797971 ! androgen receptor signaling pathway GO:0030521 74 36 0,000 0,19129639 0,20788577 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,19129639 0,20779192 ! RNA export from nucleus GO:0006405 56 37 0,000 0,19605489 0,21286465 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,19605489 0,21276863 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,19605489 0,21267271 ! organic anion transport GO:0015711 68 37 0,000 0,19605489 0,21257686 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,19605489 0,21248111 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,19605489 0,21238544 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,19605489 0,21228986 GO:0015986|ATP synthesis coupled proton transport, ! glycogen metabolic process GO:0005977 61 37 0,000 0,19605489 0,21219436 ! pigment metabolic process GO:0042440 80 37 0,000 0,19605489 0,21209895 ! spermatid differentiation GO:0048515 66 37 0,000 0,19605489 0,21200362 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,20078555 0,21702158 GO:0006956|complement activation, ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,20078555 0,21692413 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,20078555 0,21682677 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,20078555 0,21672949 ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,20078555 0,2166323 GO:0046660|female sex differentiation, ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,20078555 0,2165352 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,20078555 0,21643819 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,20078555 0,21634126 ! glucan metabolic process GO:0044042 62 38 0,000 0,20078555 0,21624442 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,20548853 0,22121047 ! organic ether metabolic process GO:0018904 55 39 0,000 0,20548853 0,22111154 ! segmentation GO:0035282 67 39 0,000 0,20548853 0,2210127 ! ion transmembrane transport GO:0034220 66 39 0,000 0,20548853 0,22091394 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,20548853 0,22081528 ! RNA modification GO:0009451 57 39 0,000 0,20548853 0,2207167 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,20548853 0,22061821 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,21016399 0,22553727 ! feeding behavior GO:0007631 59 40 0,000 0,21016399 0,22543672 ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,21016399 0,22533626 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,21481209 0,23021733 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,21481209 0,23011483 ! gliogenesis GO:0042063 88 41 0,000 0,21481209 0,23001242 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,21481209 0,2299101 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,21481209 0,22980787 ! female gamete generation GO:0007292 61 41 0,000 0,21481209 0,22970573 ! polyol metabolic process GO:0019751 66 41 0,000 0,21481209 0,22960369 ! response to reactive oxygen species GO:0000302 67 42 0,000 0,219433 0,23443863 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,219433 0,23433457 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,219433 0,23423061 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,219433 0,23412674 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,219433 0,23402296 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,22402686 0,2388164 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,22402686 0,23871064 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,22402686 0,23860497 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,22402686 0,23849939 ! striated muscle contraction GO:0006941 77 43 0,000 0,22402686 0,23839391 ! phagocytosis GO:0006909 90 43 0,000 0,22402686 0,23828851 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,22402686 0,23818322 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,22859383 0,24293143 ! biopolymer methylation GO:0043414 84 44 0,000 0,22859383 0,24282418 ! glycolysis GO:0006096 65 45 0,000 0,23313408 0,24753778 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,23313408 0,24742858 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,23313408 0,24731949 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,23313408 0,24721049 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,23313408 0,24710159 ! cell growth GO:0016049 84 45 0,000 0,23313408 0,24699278 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,23764776 0,25166396 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,23764776 0,25155324 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,24213502 0,25619035 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,24213502 0,25607774 ! methylation GO:0032259 90 47 0,000 0,24213502 0,25596522 ! Notch signaling pathway GO:0007219 96 48 0,000 0,24659601 0,26056654 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,24659601 0,26045215 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,24659601 0,26033787 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,24659601 0,26022369 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,25103089 0,26478752 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,25103089 0,26467149 ! regulation of ion transport GO:0043269 77 49 0,000 0,25103089 0,26455556 ! peptide metabolic process GO:0006518 76 49 0,000 0,25103089 0,26443973 ! response to temperature stimulus GO:0009266 76 49 0,000 0,25103089 0,264324 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,25103089 0,26420837 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,25103089 0,26409284 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,25103089 0,26397742 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,25103089 0,26386209 ! neuromuscular process GO:0050905 99 50 0,000 0,25543982 0,26837913 ! inner ear development GO:0048839 79 50 0,000 0,25543982 0,26826198 ! histone modification GO:0016570 91 50 0,000 0,25543982 0,26814494 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,25543982 0,268028 ! viral infectious cycle GO:0019058 99 51 0,000 0,25982293 0,27250827 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,25982293 0,27238953 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,25982293 0,2722709 ! excretion GO:0007588 83 51 0,000 0,25982293 0,27215236 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,25982293 0,27203393 ! vesicle organization GO:0016050 107 51 0,000 0,25982293 0,27191561 ! regulation of cell shape GO:0008360 125 51 0,000 0,25982293 0,27179738 ! membrane fusion GO:0006944 110 52 0,000 0,26418039 0,27623556 ! covalent chromatin modification GO:0016569 101 52 0,000 0,26418039 0,27611556 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,26851234 0,28052136 ! RNA catabolic process GO:0006401 93 53 0,000 0,26851234 0,28039961 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,26851234 0,28027796 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,26851234 0,28015642 ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,27281893 0,28452638 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,27281893 0,2844031 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,27281893 0,28427993 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,27281893 0,28415686 ! chloride transport GO:0006821 90 55 0,000 0,27710031 0,28849128 ! glucose catabolic process GO:0006007 82 55 0,000 0,27710031 0,2883665 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,27710031 0,28824183 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,27710031 0,28811726 ! RNA elongation GO:0006354 79 55 0,000 0,27710031 0,28799281 ! nuclear export GO:0051168 97 55 0,000 0,27710031 0,28786846 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,27710031 0,28774421 ! sensory perception of smell GO:0007608 80 56 0,000 0,28135662 0,29203798 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,28135662 0,29191204 ! proton transport GO:0015992 94 56 0,000 0,28135662 0,29178622 ! lipid modification GO:0030258 97 57 0,000 0,28558801 0,29604686 ! hydrogen transport GO:0006818 97 58 0,000 0,28979463 0,30027816 ! regulation of endocytosis GO:0030100 91 58 0,000 0,28979463 0,3001489 ! adult behavior GO:0030534 99 58 0,000 0,28979463 0,30001974 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,29397662 0,30421838 GO:0032313|regulation of Rab GTPase activity, ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,29397662 0,30408759 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,29813412 0,30825556 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,30226727 0,31239479 ! tRNA processing GO:0008033 89 61 0,000 0,30226727 0,31226065 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,30226727 0,31212664 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,30637623 0,31623389 ! gonad development GO:0008406 98 62 0,000 0,30637623 0,31609829 ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,31046112 0,3201755 ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,31046112 0,32003833 ! steroid hormone receptor signaling pathway GO:0030518 129 63 0,000 0,31046112 0,31990126 ! cell redox homeostasis GO:0045454 102 64 0,000 0,31452209 0,32394698 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,31452209 0,32380836 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,31452209 0,32366987 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,31452209 0,32353149 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,31855928 0,32754428 ! germ cell development GO:0007281 118 65 0,000 0,31855928 0,32740436 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,32257282 0,33138779 ! secondary metabolic process GO:0019748 116 66 0,000 0,32257282 0,33124635 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,32656286 0,33520061 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,32656286 0,33505767 ! hexose catabolic process GO:0019320 104 67 0,000 0,32656286 0,33491485 ! activation of immune response GO:0002253 105 67 0,000 0,32656286 0,33477215 ! amino acid transport GO:0006865 125 68 0,000 0,33052952 0,33869422 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,33052952 0,33855004 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 0,000 0,33052952 0,33840597 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,33052952 0,33826203 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,33447296 0,34215219 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,33447296 0,34200677 ! antigen processing and presentation GO:0019882 104 69 0,000 0,33447296 0,34186149 ! reproductive structure development GO:0048608 113 71 0,000 0,34229067 0,34970333 ! phosphoinositide metabolic process GO:0030384 128 72 0,000 0,34616521 0,35351167 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,35001706 0,35729361 ! fertilization GO:0009566 90 73 0,000 0,35001706 0,35714209 ! transition metal ion transport GO:0000041 126 74 0,000 0,35384634 0,36089627 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,35765319 0,3646244 ! rhythmic process GO:0048511 128 75 0,000 0,35765319 0,36446996 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,36143774 0,36817071 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,36143774 0,3680149 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,36143774 0,36785923 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,36520012 0,37153128 ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,36894045 0,37517782 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,37265887 0,378799 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,37265887 0,37863904 ! muscle cell differentiation GO:0042692 159 80 0,000 0,3763555 0,38223357 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,3763555 0,38207229 ! response to hypoxia GO:0001666 171 81 0,000 0,38003047 0,38564037 ! digestion GO:0007586 112 81 0,000 0,38003047 0,38547778 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,38003047 0,38531534 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,3836839 0,38885572 ! response to oxygen levels GO:0070482 176 83 0,000 0,38731593 0,39237142 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,39092668 0,39586262 ! response to unfolded protein GO:0006986 131 85 0,000 0,39451626 0,39932946 ! nucleosome assembly GO:0006334 122 85 0,000 0,39451626 0,39916153 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,39451626 0,39899375 ! amine biosynthetic process GO:0009309 138 86 0,000 0,39808481 0,40243363 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,39808481 0,40226461 ! chromatin assembly GO:0031497 124 86 0,000 0,39808481 0,40209574 ! alcohol catabolic process GO:0046164 130 86 0,000 0,39808481 0,401927 ! amine transport GO:0015837 155 86 0,000 0,39808481 0,40175841 ! cellular respiration GO:0045333 135 88 0,000 0,40515928 0,40872672 ! regulation of neurological system process GO:0031644 148 88 0,000 0,40515928 0,40855542 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,40515928 0,40838426 ! cellular defense response GO:0006968 114 89 0,000 0,40866545 0,41174585 ! regulation of cell morphogenesis GO:0022604 215 89 0,000 0,40866545 0,4115735 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,41215107 0,41491024 ! sterol metabolic process GO:0016125 152 91 0,000 0,41561626 0,41822364 ! response to protein stimulus GO:0051789 149 91 0,000 0,41561626 0,4180488 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,41561626 0,4178741 ! nucleosome organization GO:0034728 138 92 0,000 0,41906114 0,4211617 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,41906114 0,42098585 ! vitamin metabolic process GO:0006766 139 92 0,000 0,41906114 0,42081015 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,42248583 0,42407213 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,42589044 0,42731126 ! female pregnancy GO:0007565 164 94 0,000 0,42589044 0,42713314 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,42927509 0,43034828 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,4326399 0,43354086 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! positive regulation of immune response GO:0050778 156 96 0,000 0,4326399 0,43336036 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,43598498 0,43652928 ! protein ubiquitination GO:0016567 217 97 0,000 0,43598498 0,4363477 ! hormone metabolic process GO:0042445 157 97 0,000 0,43598498 0,43616626 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,43931045 0,43931045