pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6744-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! sarcomere organization GO:0045214 30 22 8,000 5,096E-16 1,226E-12 ! myofibril assembly GO:0030239 47 30 8,000 1,419E-14 1,707E-11 GO:0055002|striated muscle cell development, ! response to calcium ion GO:0051592 81 47 9,000 2,172E-14 1,742E-11 ! muscle cell development GO:0055001 49 32 8,000 2,759E-14 1,66E-11 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 8,000 1,199E-13 5,77E-11 ! actomyosin structure organization GO:0031032 62 37 8,000 1,199E-13 4,808E-11 ! response to metal ion GO:0010038 140 80 10,000 1,729E-13 5,943E-11 ! response to inorganic substance GO:0010035 153 86 10,000 3,939E-13 1,185E-10 ! striated muscle cell differentiation GO:0051146 82 43 8,000 5,304E-13 1,418E-10 ! muscle cell differentiation GO:0042692 159 80 8,000 1,876E-10 4,514E-08 ! negative regulation of phosphorylation GO:0042326 47 24 5,000 1,406E-09 3,076E-07 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 5,000 2,387E-09 4,785E-07 GO:0045936|negative regulation of phosphate metabolic process, ! positive regulation of locomotion GO:0040017 39 21 4,000 4,616E-08 8,543E-06 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! regulation of chemotaxis GO:0050920 40 22 4,000 5,95E-08 1,023E-05 ! induction of positive chemotaxis GO:0050930 15 9 3,000 6,374E-08 1,022E-05 ! sex determination GO:0007530 47 23 4,000 7,574E-08 1,139E-05 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 5,000 8,971E-08 1,27E-05 ! regulation of behavior GO:0050795 43 24 4,000 9,53E-08 1,274E-05 ! regulation of positive chemotaxis GO:0050926 19 12 3,000 2,476E-07 3,136E-05 GO:0050927|positive regulation of positive chemotaxis, ! C21-steroid hormone biosynthetic process GO:0006700 23 15 3,000 6,752E-07 8,122E-05 ! negative regulation of ligase activity GO:0051352 112 68 5,000 9,61E-07 1,101E-04 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! proximal/distal pattern formation GO:0009954 32 19 3,000 1,889E-06 2,066E-04 ! positive regulation of response to external stimulus GO:0032103 77 43 4,000 2,005E-06 2,098E-04 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 5,000 2,337E-06 2,342E-04 ! C21-steroid hormone metabolic process GO:0008207 33 20 3,000 2,352E-06 2,264E-04 ! apoptotic mitochondrial changes GO:0008637 41 20 3,000 2,352E-06 2,176E-04 ! induction of apoptosis by intracellular signals GO:0008629 93 45 4,000 2,525E-06 2,25E-04 ! digestion GO:0007586 112 81 5,000 2,707E-06 2,326E-04 ! pigmentation GO:0043473 100 46 4,000 2,822E-06 2,342E-04 ! positive regulation of inflammatory response GO:0050729 35 21 3,000 2,895E-06 2,321E-04 ! regulation of ligase activity GO:0051340 142 84 5,000 3,35E-06 2,6E-04 ! regulation of mast cell proliferation GO:0070666 81 48 4,000 3,498E-06 2,63E-04 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 3,000 3,525E-06 2,57E-04 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 2,000 3,772E-06 2,669E-04 ! regulation of leukocyte proliferation GO:0070663 88 51 4,000 4,744E-06 3,261E-04 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of T cell differentiation in the thymus GO:0033081 13 8 2,000 6,014E-06 4,019E-04 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 4,000 6,313E-06 4,105E-04 ! interphase of mitotic cell cycle GO:0051329 209 95 5,000 6,859E-06 4,343E-04 ! interphase GO:0051325 213 98 5,000 8,209E-06 5,065E-04 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 4,000 8,262E-06 4,97E-04 ! positive regulation of cell migration GO:0030335 126 57 4,000 8,262E-06 4,848E-04 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 2,000 1,28E-05 7,331E-04 ! regulation of smooth muscle cell migration GO:0014910 27 10 2,000 1,28E-05 7,16E-04 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 2,000 1,28E-05 6,997E-04 ! positive regulation of leukocyte migration GO:0002687 25 10 2,000 1,28E-05 6,842E-04 ! neurotransmitter secretion GO:0007269 48 30 3,000 1,281E-05 6,703E-04 ! regulation of B cell activation GO:0050864 50 30 3,000 1,281E-05 6,56E-04 ! positive regulation of cell motion GO:0051272 146 64 4,000 1,464E-05 7,34E-04 ! embryonic limb morphogenesis GO:0030326 125 65 4,000 1,58E-05 7,759E-04 GO:0035113|embryonic appendage morphogenesis, ! chondrocyte differentiation GO:0002062 24 11 2,000 1,753E-05 8,437E-04 ! regulation of leukocyte migration GO:0002685 26 11 2,000 1,753E-05 8,271E-04 ! negative regulation of glucose import GO:0046325 17 11 2,000 1,753E-05 8,112E-04 GO:0010829|negative regulation of glucose transport, ! negative regulation of protein kinase activity GO:0006469 130 67 4,000 1,833E-05 8,323E-04 ! negative regulation of cell growth GO:0030308 132 67 4,000 1,833E-05 8,169E-04 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 4,000 1,833E-05 8,021E-04 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 4,000 1,833E-05 7,877E-04 ! leukocyte chemotaxis GO:0030595 50 33 3,000 1,892E-05 7,987E-04 GO:0060326|cell chemotaxis, ! negative regulation of kinase activity GO:0033673 131 68 4,000 1,971E-05 8,178E-04 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 4,000 1,971E-05 8,039E-04 ! negative regulation of cell size GO:0045792 134 69 4,000 2,117E-05 8,49E-04 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 4,000 2,117E-05 8,351E-04 ! appendage morphogenesis GO:0035107 135 70 4,000 2,271E-05 8,814E-04 GO:0035108|limb morphogenesis, ! regulation of B cell proliferation GO:0030888 20 12 2,000 2,329E-05 8,896E-04 ! gland morphogenesis GO:0022612 29 12 2,000 2,329E-05 8,757E-04 ! negative regulation of mast cell proliferation GO:0070667 23 12 2,000 2,329E-05 8,623E-04 GO:0042130|negative regulation of T cell proliferation, ! regulation of smooth muscle cell proliferation GO:0048660 59 35 3,000 2,403E-05 8,76E-04 ! appendage development GO:0048736 136 71 4,000 2,434E-05 8,74E-04 GO:0060173|limb development, ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 4,000 2,605E-05 9,219E-04 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 4,000 2,605E-05 9,085E-04 ! negative regulation of transferase activity GO:0051348 140 72 4,000 2,605E-05 8,955E-04 ! hormone biosynthetic process GO:0042446 57 36 3,000 2,693E-05 9,127E-04 ! positive regulation of ligase activity GO:0051351 124 77 4,000 3,609E-05 1,206E-03 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 2,000 3,827E-05 1,261E-03 ! release of cytochrome c from mitochondria GO:0001836 30 14 2,000 3,827E-05 1,244E-03 ! positive regulation of phosphorylation GO:0042327 129 79 4,000 4,085E-05 1,31E-03 ! regulation of T cell proliferation GO:0042129 71 41 3,000 4,545E-05 1,439E-03 ! regulation of T cell differentiation GO:0045580 70 41 3,000 4,545E-05 1,42E-03 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 4,000 4,608E-05 1,422E-03 GO:0045937|positive regulation of phosphate metabolic process, ! negative regulation of bone remodeling GO:0046851 33 15 2,000 4,767E-05 1,452E-03 ! regulation of the force of heart contraction GO:0002026 26 15 2,000 4,767E-05 1,434E-03 ! negative regulation of growth GO:0045926 155 84 4,000 5,489E-05 1,63E-03 ! regulation of epithelial cell proliferation GO:0050678 111 43 3,000 5,497E-05 1,613E-03 ! embryonic forelimb morphogenesis GO:0035115 28 16 2,000 5,846E-05 1,695E-03 ! negative regulation of tissue remodeling GO:0034104 36 16 2,000 5,846E-05 1,675E-03 ! negative regulation of leukocyte proliferation GO:0070664 31 16 2,000 5,846E-05 1,655E-03 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! defense response to virus GO:0051607 37 16 2,000 5,846E-05 1,636E-03 ! leukocyte migration GO:0050900 68 45 3,000 6,587E-05 1,822E-03 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 2,000 7,074E-05 1,934E-03 ! neutrophil chemotaxis GO:0030593 27 17 2,000 7,074E-05 1,912E-03 ! negative regulation of homeostatic process GO:0032845 33 17 2,000 7,074E-05 1,891E-03 ! positive regulation of defense response GO:0031349 76 47 3,000 7,827E-05 2,07E-03 ! peptidyl-serine phosphorylation GO:0018105 38 18 2,000 8,459E-05 2,212E-03 ! regulation of inflammatory response GO:0050727 75 48 3,000 8,507E-05 2,201E-03 ! regulation of lymphocyte differentiation GO:0045619 81 48 3,000 8,507E-05 2,177E-03 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 4,000 8,925E-05 2,26E-03 GO:0010498|proteasomal protein catabolic process, ! forelimb morphogenesis GO:0035136 32 19 2,000 1,001E-04 2,509E-03 ! response to alkaloid GO:0043279 38 20 2,000 1,173E-04 2,911E-03 ! peptidyl-serine modification GO:0018209 43 20 2,000 1,173E-04 2,881E-03 ! regulation of glucose import GO:0046324 29 20 2,000 1,173E-04 2,852E-03 GO:0010827|regulation of glucose transport, ! negative regulation of T cell activation GO:0050868 40 20 2,000 1,173E-04 2,823E-03 ! negative regulation of translation GO:0017148 29 20 2,000 1,173E-04 2,795E-03 ! response to UV GO:0009411 104 53 3,000 1,257E-04 2,964E-03 ! cell cycle arrest GO:0007050 213 100 4,000 1,259E-04 2,94E-03 ! inactivation of MAPK activity GO:0000188 39 21 2,000 1,364E-04 3,156E-03 ! cell structure disassembly during apoptosis GO:0006921 30 21 2,000 1,364E-04 3,126E-03 ! collagen catabolic process GO:0030574 28 21 2,000 1,364E-04 3,096E-03 ! apoptotic nuclear changes GO:0030262 32 22 2,000 1,574E-04 3,539E-03 ! response to glucocorticoid stimulus GO:0051384 38 22 2,000 1,574E-04 3,507E-03 ! positive regulation of B cell activation GO:0050871 38 22 2,000 1,574E-04 3,474E-03 ! regulation of bone remodeling GO:0046850 137 57 3,000 1,67E-04 3,653E-03 ! regulation of tissue remodeling GO:0034103 140 58 3,000 1,787E-04 3,874E-03 ! regulation of cell-matrix adhesion GO:0001952 78 23 2,000 1,804E-04 3,875E-03 GO:0010810|regulation of cell-substrate adhesion, ! activation of pro-apoptotic gene products GO:0008633 47 23 2,000 1,804E-04 3,841E-03 ! regulation of neurotransmitter levels GO:0001505 97 60 3,000 2,039E-04 4,303E-03 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 2,000 2,054E-04 4,298E-03 ! response to corticosteroid stimulus GO:0031960 41 24 2,000 2,054E-04 4,261E-03 ! leukocyte homeostasis GO:0001776 44 24 2,000 2,054E-04 4,224E-03 ! negative regulation of bone resorption GO:0045779 10 5 1,000 2,28E-04 4,649E-03 ! regulation of collagen biosynthetic process GO:0032965 6 5 1,000 2,28E-04 4,61E-03 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 1,000 2,28E-04 4,572E-03 ! response to protozoan GO:0001562 10 5 1,000 2,28E-04 4,534E-03 ! epithelial cell proliferation GO:0050673 9 5 1,000 2,28E-04 4,497E-03 ! negative regulation of survival gene product expression GO:0008634 8 5 1,000 2,28E-04 4,46E-03 ! neutrophil mediated immunity GO:0002446 7 5 1,000 2,28E-04 4,425E-03 ! microvillus organization GO:0032528 7 5 1,000 2,28E-04 4,389E-03 GO:0030033|microvillus assembly, ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 2,28E-04 4,354E-03 ! peptidyl-threonine phosphorylation GO:0018107 20 5 1,000 2,28E-04 4,32E-03 ! homeostasis of number of cells within a tissue GO:0048873 12 5 1,000 2,28E-04 4,286E-03 ! meiotic chromosome segregation GO:0045132 7 5 1,000 2,28E-04 4,253E-03 ! neural tube patterning GO:0021532 7 5 1,000 2,28E-04 4,22E-03 ! positive regulation of chemokine production GO:0032722 8 5 1,000 2,28E-04 4,188E-03 ! B cell homeostasis GO:0001782 13 5 1,000 2,28E-04 4,156E-03 ! regulation of mitochondrial depolarization GO:0051900 13 5 1,000 2,28E-04 4,125E-03 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 1,000 2,28E-04 4,094E-03 ! hemopoietic progenitor cell differentiation GO:0002244 14 5 1,000 2,28E-04 4,064E-03 ! stem cell division GO:0017145 11 5 1,000 2,28E-04 4,034E-03 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 1,000 2,28E-04 4,005E-03 ! regulation of homeostatic process GO:0032844 134 62 3,000 2,315E-04 4,036E-03 ! vasculogenesis GO:0001570 46 25 2,000 2,326E-04 4,026E-03 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 2,000 2,937E-04 5,048E-03 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 2,000 2,937E-04 5,012E-03 ! multicellular organismal catabolic process GO:0044243 36 27 2,000 2,937E-04 4,977E-03 ! male gonad development GO:0008584 44 27 2,000 2,937E-04 4,942E-03 ! regulation of chromosome organization GO:0033044 42 27 2,000 2,937E-04 4,908E-03 ! negative regulation of lymphocyte activation GO:0051250 53 27 2,000 2,937E-04 4,874E-03 ! cellular hormone metabolic process GO:0034754 113 67 3,000 3,122E-04 5,145E-03 ! negative regulation of protein modification process GO:0031400 60 28 2,000 3,278E-04 5,366E-03 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 1,000 3,41E-04 5,543E-03 GO:0033135|regulation of peptidyl-serine phosphorylation, ! regulation of immunoglobulin secretion GO:0051023 6 6 1,000 3,41E-04 5,506E-03 ! regulation of collagen metabolic process GO:0010712 9 6 1,000 3,41E-04 5,469E-03 ! establishment of spindle localization GO:0051293 12 6 1,000 3,41E-04 5,433E-03 GO:0051653|spindle localization, ! neural nucleus development GO:0048857 14 6 1,000 3,41E-04 5,397E-03 ! regulation of myeloid cell apoptosis GO:0033032 13 6 1,000 3,41E-04 5,362E-03 ! neutrophil homeostasis GO:0001780 10 6 1,000 3,41E-04 5,327E-03 ! salivary gland morphogenesis GO:0007435 13 6 1,000 3,41E-04 5,293E-03 ! triglyceride catabolic process GO:0019433 10 6 1,000 3,41E-04 5,259E-03 ! organ or tissue specific immune response GO:0002251 7 6 1,000 3,41E-04 5,225E-03 ! negative regulation of B cell activation GO:0050869 13 6 1,000 3,41E-04 5,192E-03 ! negative regulation of leukocyte activation GO:0002695 56 30 2,000 4,034E-04 6,105E-03 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 3,000 4,113E-04 6,185E-03 ! collagen metabolic process GO:0032963 45 31 2,000 4,451E-04 6,651E-03 ! regulation of transcription factor activity GO:0051090 126 74 3,000 4,566E-04 6,782E-03 GO:0090046|regulation of transcription regulator activity, ! neurotransmitter transport GO:0006836 123 74 3,000 4,566E-04 6,74E-03 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 4,758E-04 6,981E-03 ! N-terminal protein amino acid acetylation GO:0006474 13 7 1,000 4,758E-04 6,939E-03 ! mRNA stabilization GO:0048255 18 7 1,000 4,758E-04 6,897E-03 GO:0043489|RNA stabilization, ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 1,000 4,758E-04 6,856E-03 ! glycerol ether catabolic process GO:0044269 12 7 1,000 4,758E-04 6,815E-03 GO:0046464|acylglycerol catabolic process, ! organ growth GO:0035265 15 7 1,000 4,758E-04 6,774E-03 ! B cell lineage commitment GO:0002326 21 7 1,000 4,758E-04 6,735E-03 ! T cell lineage commitment GO:0002360 16 7 1,000 4,758E-04 6,695E-03 ! peptidyl-threonine modification GO:0018210 25 7 1,000 4,758E-04 6,656E-03 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 1,000 4,758E-04 6,618E-03 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 1,000 4,758E-04 6,58E-03 ! regulation of protein homodimerization activity GO:0043496 18 7 1,000 4,758E-04 6,542E-03 ! defense response to Gram-negative bacterium GO:0050829 9 7 1,000 4,758E-04 6,505E-03 ! metanephros development GO:0001656 74 32 2,000 4,894E-04 6,653E-03 ! negative regulation of MAP kinase activity GO:0043407 69 32 2,000 4,894E-04 6,615E-03 ! hindbrain development GO:0030902 61 32 2,000 4,894E-04 6,578E-03 ! steroid biosynthetic process GO:0006694 131 76 3,000 5,054E-04 6,755E-03 ! response to steroid hormone stimulus GO:0048545 137 78 3,000 5,577E-04 7,414E-03 ! regulation of striated muscle tissue development GO:0016202 69 34 2,000 5,863E-04 7,751E-03 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 2,000 5,863E-04 7,708E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 6,324E-04 8,27E-03 ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 1,000 6,324E-04 8,225E-03 ! neutral lipid catabolic process GO:0046461 13 8 1,000 6,324E-04 8,181E-03 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 1,000 6,324E-04 8,137E-03 ! T-helper 1 type immune response GO:0042088 12 8 1,000 6,324E-04 8,094E-03 ! glycerolipid catabolic process GO:0046503 13 8 1,000 6,324E-04 8,051E-03 ! pigment granule organization GO:0048753 16 8 1,000 6,324E-04 8,009E-03 ! ER overload response GO:0006983 12 8 1,000 6,324E-04 7,967E-03 ! regulation of pigmentation during development GO:0048070 24 8 1,000 6,324E-04 7,925E-03 ! melanin metabolic process GO:0006582 15 8 1,000 6,324E-04 7,884E-03 ! positive regulation of endothelial cell migration GO:0010595 19 8 1,000 6,324E-04 7,844E-03 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 1,000 6,324E-04 7,803E-03 ! regulation of vascular permeability GO:0043114 12 8 1,000 6,324E-04 7,764E-03 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 1,000 6,324E-04 7,724E-03 ! response to UV-B GO:0010224 16 8 1,000 6,324E-04 7,685E-03 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 1,000 6,324E-04 7,647E-03 ! myeloid cell homeostasis GO:0002262 13 8 1,000 6,324E-04 7,608E-03 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 1,000 6,324E-04 7,571E-03 ! regulation of muscle development GO:0048634 70 35 2,000 6,39E-04 7,611E-03 ! response to hypoxia GO:0001666 171 81 3,000 6,433E-04 7,625E-03 ! negative regulation of cell activation GO:0050866 65 36 2,000 6,947E-04 8,193E-03 ! response to oxygen levels GO:0070482 176 83 3,000 7,053E-04 8,278E-03 ! negative regulation of transport GO:0051051 153 84 3,000 7,378E-04 8,617E-03 ! regulation of protein stability GO:0031647 73 37 2,000 7,533E-04 8,756E-03 ! mitochondrion organization GO:0007005 148 86 3,000 8,06E-04 9,323E-03 ! microtubule bundle formation GO:0001578 21 9 1,000 8,106E-04 9,331E-03 ! middle ear morphogenesis GO:0042474 14 9 1,000 8,106E-04 9,287E-03 ! T cell selection GO:0045058 23 9 1,000 8,106E-04 9,243E-03 ! behavioral fear response GO:0001662 22 9 1,000 8,106E-04 9,199E-03 GO:0002209|behavioral defense response, ! motor axon guidance GO:0008045 16 9 1,000 8,106E-04 9,156E-03 ! alpha-beta T cell differentiation GO:0046632 21 9 1,000 8,106E-04 9,113E-03 ! regulation of mitochondrial membrane potential GO:0051881 17 9 1,000 8,106E-04 9,071E-03 ! regulation of telomere maintenance GO:0032204 14 9 1,000 8,106E-04 9,029E-03 ! nucleus organization GO:0006997 67 38 2,000 8,15E-04 9,036E-03 ! positive regulation of leukocyte proliferation GO:0070665 62 38 2,000 8,15E-04 8,995E-03 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! positive regulation of protein modification process GO:0031401 136 88 3,000 8,785E-04 9,652E-03 ! regulation of DNA binding GO:0051101 155 88 3,000 8,785E-04 9,608E-03 ! gland development GO:0048732 206 88 3,000 8,785E-04 9,564E-03 ! development of primary male sexual characteristics GO:0046546 66 39 2,000 8,798E-04 9,535E-03 ! regulation of cell adhesion GO:0030155 212 89 3,000 9,165E-04 9,888E-03 ! multicellular organismal metabolic process GO:0044236 57 40 2,000 9,478E-04 0,01018048 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 1,01E-03 0,01080054 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 1,000 1,01E-03 0,01075275 ! lung alveolus development GO:0048286 26 10 1,000 1,01E-03 0,01070538 ! regulation of chemokine biosynthetic process GO:0045073 12 10 1,000 1,01E-03 0,01065843 ! negative regulation of striated muscle development GO:0045843 19 10 1,000 1,01E-03 0,01061188 ! myeloid leukocyte mediated immunity GO:0002444 14 10 1,000 1,01E-03 0,01056575 ! B cell proliferation GO:0042100 18 10 1,000 1,01E-03 0,01052001 ! regulation of bone resorption GO:0045124 25 10 1,000 1,01E-03 0,01047466 ! alpha-beta T cell activation GO:0046631 23 10 1,000 1,01E-03 0,01042971 ! positive regulation of interleukin-6 production GO:0032755 14 10 1,000 1,01E-03 0,01038514 ! salivary gland development GO:0007431 27 10 1,000 1,01E-03 0,01034094 ! positive regulation of acute inflammatory response GO:0002675 16 10 1,000 1,01E-03 0,01029713 ! midbrain development GO:0030901 13 10 1,000 1,01E-03 0,01025368 ! detection of calcium ion GO:0005513 23 10 1,000 1,01E-03 0,0102106 ! oocyte development GO:0048599 17 10 1,000 1,01E-03 0,01016787 ! response to nicotine GO:0035094 20 10 1,000 1,01E-03 0,01012551 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 1,000 1,01E-03 0,01008349 ! localization within membrane GO:0051668 20 10 1,000 1,01E-03 0,01004182 ! T cell differentiation GO:0030217 81 41 2,000 1,019E-03 0,01008983 ! regulation of defense response GO:0031347 149 92 3,000 1,037E-03 0,01022716 ! positive regulation of MAP kinase activity GO:0043406 160 93 3,000 1,08E-03 0,0106038 ! negative regulation of multicellular organismal process GO:0051241 166 93 3,000 1,08E-03 0,01056069 ! positive regulation of transcription factor activity GO:0051091 62 42 2,000 1,094E-03 0,0106525 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 2,000 1,094E-03 0,01060955 ! regulation of T cell activation GO:0050863 158 94 3,000 1,124E-03 0,01085684 ! neural tube development GO:0021915 77 43 2,000 1,171E-03 0,01127434 ! negative regulation of muscle development GO:0048635 20 11 1,000 1,231E-03 0,01179591 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 1,000 1,231E-03 0,0117491 ! detection of mechanical stimulus GO:0050982 22 11 1,000 1,231E-03 0,01170267 ! blood vessel remodeling GO:0001974 29 11 1,000 1,231E-03 0,01165659 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 1,000 1,231E-03 0,01161088 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 1,000 1,231E-03 0,01156552 ! peptide or protein amino-terminal blocking GO:0018409 21 11 1,000 1,231E-03 0,01152052 ! negative regulation of ossification GO:0030279 26 11 1,000 1,231E-03 0,01147587 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 1,000 1,231E-03 0,01143156 ! DNA methylation GO:0006306 19 11 1,000 1,231E-03 0,01138759 GO:0006305|DNA alkylation, ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 1,000 1,231E-03 0,01134396 ! oocyte differentiation GO:0009994 18 11 1,000 1,231E-03 0,01130067 ! thymus development GO:0048538 27 11 1,000 1,231E-03 0,0112577 ! defense response to Gram-positive bacterium GO:0050830 13 11 1,000 1,231E-03 0,01121505 ! male sex differentiation GO:0046661 76 44 2,000 1,253E-03 0,01137441 ! hormone metabolic process GO:0042445 157 97 3,000 1,263E-03 0,01141948 ! regulation of protein localization GO:0032880 176 97 3,000 1,263E-03 0,01137671 ! response to virus GO:0009615 160 98 3,000 1,311E-03 0,01177286 ! negative regulation of cell migration GO:0030336 115 46 2,000 1,426E-03 0,01275338 ! positive regulation of protein transport GO:0051222 72 46 2,000 1,426E-03 0,01270614 ! oligodendrocyte differentiation GO:0048709 16 12 1,000 1,472E-03 0,01306908 ! focal adhesion formation GO:0048041 35 12 1,000 1,472E-03 0,01302103 ! fear response GO:0042596 26 12 1,000 1,472E-03 0,01297333 ! histone acetylation GO:0016573 26 12 1,000 1,472E-03 0,01292598 ! peptidyl-lysine modification GO:0018205 21 12 1,000 1,472E-03 0,01287898 ! T cell homeostasis GO:0043029 25 12 1,000 1,472E-03 0,01283232 ! spleen development GO:0048536 22 12 1,000 1,472E-03 0,01278599 ! digestive tract morphogenesis GO:0048546 26 12 1,000 1,472E-03 0,01274 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 1,000 1,472E-03 0,01269434 ! positive regulation of DNA binding GO:0043388 73 47 2,000 1,518E-03 0,01304188 ! positive regulation of cell cycle GO:0045787 89 48 2,000 1,613E-03 0,01381327 ! cellular component disassembly GO:0022411 86 48 2,000 1,613E-03 0,01376429 ! activation of caspase activity GO:0006919 84 48 2,000 1,613E-03 0,01371565 ! induction of apoptosis by extracellular signals GO:0008624 89 49 2,000 1,712E-03 0,01450772 ! regulation of chemokine production GO:0032642 18 13 1,000 1,734E-03 0,01464024 ! endocrine pancreas development GO:0031018 22 13 1,000 1,734E-03 0,01458905 ! regulation of skeletal muscle fiber development GO:0048742 32 13 1,000 1,734E-03 0,01453822 ! plasma membrane organization GO:0007009 24 13 1,000 1,734E-03 0,01448774 ! Golgi organization GO:0007030 24 13 1,000 1,734E-03 0,0144376 ! exocrine system development GO:0035272 32 13 1,000 1,734E-03 0,01438782 ! negative regulation of mitotic cell cycle GO:0045930 33 13 1,000 1,734E-03 0,01433838 ! regulation of monooxygenase activity GO:0032768 33 13 1,000 1,734E-03 0,01428927 ! regulation of acute inflammatory response GO:0002673 21 13 1,000 1,734E-03 0,0142405 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 1,000 1,734E-03 0,01419207 ! regulation of mRNA stability GO:0043488 31 13 1,000 1,734E-03 0,01414396 ! actin filament polymerization GO:0030041 24 13 1,000 1,734E-03 0,01409618 ! regulation of ossification GO:0030278 117 50 2,000 1,815E-03 0,01470651 ! negative regulation of immune system process GO:0002683 95 50 2,000 1,815E-03 0,01465716 ! positive regulation of binding GO:0051099 78 51 2,000 1,922E-03 0,01546681 ! response to estrogen stimulus GO:0043627 93 51 2,000 1,922E-03 0,01541526 ! epithelial tube morphogenesis GO:0060562 98 51 2,000 1,922E-03 0,01536404 ! N-terminal protein amino acid modification GO:0031365 27 14 1,000 2,017E-03 0,01606799 ! hair follicle morphogenesis GO:0031069 26 14 1,000 2,017E-03 0,01601496 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 1,000 2,017E-03 0,01596228 GO:0060675|ureteric bud morphogenesis, ! T cell differentiation in the thymus GO:0033077 31 14 1,000 2,017E-03 0,01590994 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 1,000 2,017E-03 0,01585795 ! regulation of T-helper 2 type immune response GO:0002828 24 14 1,000 2,017E-03 0,01580629 ! response to gamma radiation GO:0010332 28 14 1,000 2,017E-03 0,01575498 ! regulation of RNA stability GO:0043487 32 14 1,000 2,017E-03 0,01570399 ! regulation of angiogenesis GO:0045765 114 52 2,000 2,033E-03 0,01577593 ! regulation of muscle contraction GO:0006937 81 52 2,000 2,033E-03 0,0157252 ! cartilage development GO:0051216 90 52 2,000 2,033E-03 0,0156748 ! regulation of skeletal muscle tissue development GO:0048641 35 15 1,000 2,32E-03 0,01783205 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 1,000 2,32E-03 0,01777526 ! regulation of exocytosis GO:0017157 22 15 1,000 2,32E-03 0,01771883 ! regulation of T-helper cell differentiation GO:0045622 26 15 1,000 2,32E-03 0,01766276 ! lymphocyte homeostasis GO:0002260 30 15 1,000 2,32E-03 0,01760704 ! positive regulation of caspase activity GO:0043280 95 55 2,000 2,388E-03 0,01806559 GO:0010952|positive regulation of peptidase activity, ! aging GO:0007568 103 55 2,000 2,388E-03 0,01800896 ! negative regulation of cell motion GO:0051271 134 55 2,000 2,388E-03 0,01795268 ! negative regulation of microtubule depolymerization GO:0007026 46 16 1,000 2,643E-03 0,01980898 GO:0031114|regulation of microtubule depolymerization, ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 1,000 2,643E-03 0,01974746 ! cytokine-mediated signaling pathway GO:0019221 97 59 2,000 2,918E-03 0,02173281 ! DNA catabolic process GO:0006308 86 59 2,000 2,918E-03 0,02166574 ! metencephalon development GO:0022037 30 17 1,000 2,986E-03 0,02210404 ! negative regulation of hormone secretion GO:0046888 25 17 1,000 2,986E-03 0,02203624 ! negative regulation of cell cycle process GO:0010948 32 17 1,000 2,986E-03 0,02196885 ! regulation of viral genome replication GO:0045069 28 17 1,000 2,986E-03 0,02190187 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 1,000 2,986E-03 0,0218353 ! regulation of survival gene product expression GO:0045884 33 17 1,000 2,986E-03 0,02176913 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 1,000 2,986E-03 0,02170337 ! regulation of protein binding GO:0043393 33 17 1,000 2,986E-03 0,02163799 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 1,000 2,986E-03 0,02157301 ! regulation of heart contraction GO:0008016 110 60 2,000 3,06E-03 0,02204593 ! protein amino acid autophosphorylation GO:0046777 141 60 2,000 3,06E-03 0,02198012 ! negative regulation of response to stimulus GO:0048585 100 60 2,000 3,06E-03 0,0219147 ! kidney development GO:0001822 122 60 2,000 3,06E-03 0,02184967 ! positive regulation of anti-apoptosis GO:0045768 39 18 1,000 3,348E-03 0,02383536 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 1,000 3,348E-03 0,02376504 ! epidermis morphogenesis GO:0048730 40 18 1,000 3,348E-03 0,02369515 ! cell-substrate junction assembly GO:0007044 54 18 1,000 3,348E-03 0,02362566 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 1,000 3,348E-03 0,02355658 ! regulation of immunoglobulin production GO:0002637 43 18 1,000 3,348E-03 0,0234879 ! ear development GO:0043583 103 62 2,000 3,359E-03 0,02349195 ! gonad development GO:0008406 98 62 2,000 3,359E-03 0,02342385 ! positive regulation of translation GO:0045727 30 19 1,000 3,731E-03 0,02594168 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 1,000 3,731E-03 0,02586692 ! pigmentation during development GO:0048066 41 19 1,000 3,731E-03 0,02579259 ! neuromuscular junction development GO:0007528 34 19 1,000 3,731E-03 0,02571869 ! regulation of endothelial cell migration GO:0010594 44 19 1,000 3,731E-03 0,02564521 ! cellular pigmentation GO:0033059 36 19 1,000 3,731E-03 0,02557214 ! peptide hormone secretion GO:0030072 31 19 1,000 3,731E-03 0,0254995 ! regulation of cytokine biosynthetic process GO:0042035 95 65 2,000 3,839E-03 0,02616423 ! germ cell development GO:0007281 118 65 2,000 3,839E-03 0,02609032 ! actin filament organization GO:0007015 148 66 2,000 4,007E-03 0,02716063 ! protein amino acid acetylation GO:0006473 39 20 1,000 4,132E-03 0,02792631 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 1,000 4,132E-03 0,02784808 ! pancreas development GO:0031016 35 20 1,000 4,132E-03 0,0277703 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 1,000 4,132E-03 0,02769294 ! actin polymerization or depolymerization GO:0008154 48 20 1,000 4,132E-03 0,02761602 ! peptide secretion GO:0002790 35 20 1,000 4,132E-03 0,02753952 ! detection of chemical stimulus GO:0009593 37 20 1,000 4,132E-03 0,02746344 ! lung development GO:0030324 144 67 2,000 4,181E-03 0,02771015 ! homeostasis of number of cells GO:0048872 114 67 2,000 4,181E-03 0,02763402 ! urogenital system development GO:0001655 137 69 2,000 4,541E-03 0,02993086 ! hormone secretion GO:0046879 38 21 1,000 4,553E-03 0,02992819 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 1,000 4,553E-03 0,02984664 ! hindlimb morphogenesis GO:0035137 43 21 1,000 4,553E-03 0,02976554 ! ovarian follicle development GO:0001541 35 21 1,000 4,553E-03 0,02968487 ! cell aging GO:0007569 44 21 1,000 4,553E-03 0,02960464 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 1,000 4,553E-03 0,02952484 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 1,000 4,553E-03 0,02944548 ! oogenesis GO:0048477 36 21 1,000 4,553E-03 0,02936653 ! DNA modification GO:0006304 34 21 1,000 4,553E-03 0,02928801 ! positive regulation of osteoblast differentiation GO:0045669 49 21 1,000 4,553E-03 0,02920991 ! response to cytokine stimulus GO:0034097 63 21 1,000 4,553E-03 0,02913223 ! gut development GO:0048565 39 21 1,000 4,553E-03 0,02905495 ! respiratory tube development GO:0030323 150 70 2,000 4,727E-03 0,03009033 ! reproductive structure development GO:0048608 113 71 2,000 4,919E-03 0,03122574 ! humoral immune response GO:0006959 109 71 2,000 4,919E-03 0,03114357 ! regeneration GO:0031099 41 22 1,000 4,992E-03 0,03152551 ! cellular response to reactive oxygen species GO:0034614 31 22 1,000 4,992E-03 0,03144298 ! ureteric bud development GO:0001657 43 22 1,000 4,992E-03 0,03136088 ! renal system process GO:0003014 41 22 1,000 4,992E-03 0,03127921 ! positive regulation of intracellular transport GO:0032388 37 22 1,000 4,992E-03 0,03119797 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 1,000 4,992E-03 0,03111714 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 1,000 4,992E-03 0,03103674 ! regulation of caspase activity GO:0043281 122 72 2,000 5,115E-03 0,03171668 ! respiratory system development GO:0060541 153 72 2,000 5,115E-03 0,03163515 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 5,45E-03 0,03362516 ! regulation of anti-apoptosis GO:0045767 53 23 1,000 5,45E-03 0,03353916 ! response to ethanol GO:0045471 46 23 1,000 5,45E-03 0,0334536 ! regulation of viral reproduction GO:0050792 38 23 1,000 5,45E-03 0,03336848 ! regulation of interleukin-6 production GO:0032675 29 23 1,000 5,45E-03 0,03328378 ! platelet activation GO:0030168 37 23 1,000 5,45E-03 0,03319952 ! hormone transport GO:0009914 40 23 1,000 5,45E-03 0,03311568 ! response to molecule of bacterial origin GO:0002237 34 23 1,000 5,45E-03 0,03303227 ! regulation of endopeptidase activity GO:0052548 125 74 2,000 5,521E-03 0,03337367 ! eye development GO:0001654 143 74 2,000 5,521E-03 0,03329003 ! lymphocyte differentiation GO:0030098 167 75 2,000 5,731E-03 0,03446998 ! positive regulation of fibroblast proliferation GO:0048146 43 24 1,000 5,927E-03 0,0355637 ! multicellular organismal response to stress GO:0033555 49 24 1,000 5,927E-03 0,03547524 ! regulation of alpha-beta T cell activation GO:0046634 42 24 1,000 5,927E-03 0,03538721 ! lymphocyte proliferation GO:0046651 48 24 1,000 5,927E-03 0,03529962 ! regulation of oxidoreductase activity GO:0051341 46 24 1,000 5,927E-03 0,03521246 ! development of primary sexual characteristics GO:0045137 124 76 2,000 5,945E-03 0,03523313 ! positive regulation of lymphocyte activation GO:0051251 127 77 2,000 6,165E-03 0,03644414 ! blood coagulation GO:0007596 146 78 2,000 6,389E-03 0,03767746 GO:0050817|coagulation, ! negative regulation of organelle organization GO:0010639 161 78 2,000 6,389E-03 0,03758534 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 1,000 6,422E-03 0,03768895 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 1,000 6,422E-03 0,03759725 ! myelination GO:0042552 45 25 1,000 6,422E-03 0,03750599 ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 6,422E-03 0,03741518 ! somitogenesis GO:0001756 43 25 1,000 6,422E-03 0,03732481 ! positive regulation of protein secretion GO:0050714 36 25 1,000 6,422E-03 0,03723487 ! neural tube closure GO:0001843 49 25 1,000 6,422E-03 0,03714536 GO:0060606|tube closure, ! regulation of peptidase activity GO:0052547 134 79 2,000 6,618E-03 0,03818614 ! molting cycle process GO:0022404 50 26 1,000 6,936E-03 0,03992258 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 1,000 6,936E-03 0,0398273 ! regulation of endothelial cell proliferation GO:0001936 57 26 1,000 6,936E-03 0,03973247 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 1,000 6,936E-03 0,0396381 ! cellular response to oxidative stress GO:0034599 39 26 1,000 6,936E-03 0,03954417 ! response to estradiol stimulus GO:0032355 40 26 1,000 6,936E-03 0,03945068 ! positive regulation of MAPKKK cascade GO:0043410 47 26 1,000 6,936E-03 0,03935764 ! positive regulation of nuclear division GO:0051785 40 26 1,000 6,936E-03 0,03926503 GO:0045840|positive regulation of mitosis, ! regulation of osteoblast differentiation GO:0045667 65 26 1,000 6,936E-03 0,03917286 ! leukocyte proliferation GO:0070661 52 26 1,000 6,936E-03 0,03908112 GO:0032943|mononuclear cell proliferation, ! T cell activation GO:0042110 168 81 2,000 7,091E-03 0,03986226 ! response to drug GO:0042493 143 82 2,000 7,335E-03 0,04113607 ! regulation of fibroblast proliferation GO:0048145 52 27 1,000 7,467E-03 0,04178165 ! protein amino acid acylation GO:0043543 55 27 1,000 7,467E-03 0,04168471 ! mitochondrial membrane organization GO:0007006 57 27 1,000 7,467E-03 0,04158822 ! response to toxin GO:0009636 47 27 1,000 7,467E-03 0,04149217 ! primary neural tube formation GO:0014020 51 27 1,000 7,467E-03 0,04139657 ! hemostasis GO:0007599 158 84 2,000 7,837E-03 0,04334605 ! dendrite development GO:0016358 59 28 1,000 8,016E-03 0,04423726 ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 8,016E-03 0,04413603 ! positive regulation of T cell differentiation GO:0045582 42 28 1,000 8,016E-03 0,04403526 ! peptidyl-tyrosine modification GO:0018212 50 28 1,000 8,016E-03 0,04393496 ! positive regulation of cell activation GO:0050867 145 85 2,000 8,095E-03 0,04426698 GO:0002696|positive regulation of leukocyte activation, ! tube morphogenesis GO:0035239 176 86 2,000 8,359E-03 0,04560404 ! cellular iron ion homeostasis GO:0006879 51 29 1,000 8,583E-03 0,04672219 ! regulation of production of molecular mediator of immune response GO:0002700 61 29 1,000 8,583E-03 0,04661672 ! response to organic cyclic substance GO:0014070 55 29 1,000 8,583E-03 0,04651173 ! cellular response to extracellular stimulus GO:0031668 48 29 1,000 8,583E-03 0,0464072 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 1,000 8,583E-03 0,04630315 ! negative regulation of neuron apoptosis GO:0043524 56 29 1,000 8,583E-03 0,04619957 ! tissue homeostasis GO:0001894 48 29 1,000 8,583E-03 0,04609644 GO:0048871|multicellular organismal homeostasis, ! regulation of protein transport GO:0051223 154 87 2,000 8,627E-03 0,04623011 GO:0070201|regulation of establishment of protein localization, ! cell junction assembly GO:0034329 78 30 1,000 9,167E-03 0,04901547 ! acute-phase response GO:0006953 49 30 1,000 9,167E-03 0,04890678 ! positive regulation of multicellular organism growth GO:0040018 51 30 1,000 9,167E-03 0,04879858 ! ensheathment of neurons GO:0007272 57 30 1,000 9,167E-03 0,04869086 GO:0008366|axon ensheathment, ! response to heat GO:0009408 50 30 1,000 9,167E-03 0,04858361 ! ossification GO:0001503 188 90 2,000 9,463E-03 0,05003901 ! regulation of cell cycle process GO:0010564 149 90 2,000 9,463E-03 0,04992928 ! sex differentiation GO:0007548 145 90 2,000 9,463E-03 0,04982002 ! bone development GO:0060348 189 91 2,000 9,752E-03 0,05122762 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 1,000 9,769E-03 0,05120757 ! ovulation cycle process GO:0022602 49 31 1,000 9,769E-03 0,05109625 ! positive regulation of T cell proliferation GO:0042102 52 31 1,000 9,769E-03 0,05098541 ! peptide transport GO:0015833 55 31 1,000 9,769E-03 0,05087505 ! triglyceride metabolic process GO:0006641 43 31 1,000 9,769E-03 0,05076517 ! iron ion homeostasis GO:0055072 54 31 1,000 9,769E-03 0,05065577 ! negative regulation of transcription regulator activity GO:0090048 58 31 1,000 9,769E-03 0,05054683 GO:0043433|negative regulation of transcription factor activity, ! regulation of membrane potential GO:0042391 164 93 2,000 0,01034415 0,05340779 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 1,000 0,01038767 0,05351761 ! response to hydrogen peroxide GO:0042542 50 32 1,000 0,01038767 0,05340326 ! spindle organization GO:0007051 46 32 1,000 0,01038767 0,05328939 ! response to ionizing radiation GO:0010212 65 32 1,000 0,01038767 0,05317601 ! response to mechanical stimulus GO:0009612 57 32 1,000 0,01038767 0,05306311 ! ovulation cycle GO:0042698 51 32 1,000 0,01038767 0,05295069 ! peripheral nervous system development GO:0007422 64 32 1,000 0,01038767 0,05283874 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 1,000 0,01038767 0,05272727 ! post-embryonic development GO:0009791 69 33 1,000 0,01102323 0,05583555 ! leukocyte differentiation GO:0002521 202 96 2,000 0,01127151 0,05697321 ! detection of stimulus GO:0051606 151 96 2,000 0,01127151 0,05685377 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 1,000 0,01167554 0,0587685 ! glial cell differentiation GO:0010001 63 34 1,000 0,01167554 0,05864581 ! skeletal muscle tissue development GO:0007519 186 99 2,000 0,01224538 0,06137995 GO:0060538|skeletal muscle organ development, ! negative regulation of secretion GO:0051048 63 35 1,000 0,01234442 0,06174775 ! negative regulation of cell adhesion GO:0007162 81 35 1,000 0,01234442 0,06161964 ! female gonad development GO:0008585 58 35 1,000 0,01234442 0,06149206 ! neutral lipid metabolic process GO:0006638 50 35 1,000 0,01234442 0,06136501 GO:0006639|acylglycerol metabolic process, ! calcium-mediated signaling GO:0019722 62 35 1,000 0,01234442 0,06123849 ! regulation of microtubule-based process GO:0032886 78 35 1,000 0,01234442 0,06111248 ! neural tube formation GO:0001841 67 35 1,000 0,01234442 0,060987 ! mitotic sister chromatid segregation GO:0000070 57 36 1,000 0,0130297 0,06424068 ! positive regulation of JAK-STAT cascade GO:0046427 50 36 1,000 0,0130297 0,06410931 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 1,000 0,0130297 0,06397847 ! cell junction organization GO:0034330 86 36 1,000 0,0130297 0,06384817 ! positive regulation of cell development GO:0010720 80 36 1,000 0,0130297 0,0637184 ! androgen receptor signaling pathway GO:0030521 74 36 1,000 0,0130297 0,06358915 ! meiosis I GO:0007127 65 37 1,000 0,01373121 0,06687709 ! sister chromatid segregation GO:0000819 58 37 1,000 0,01373121 0,06674198 ! tissue remodeling GO:0048771 76 37 1,000 0,01373121 0,06660742 ! negative regulation of DNA binding GO:0043392 68 37 1,000 0,01373121 0,0664734 ! glycerol ether metabolic process GO:0006662 53 37 1,000 0,01373121 0,06633992 ! glycogen metabolic process GO:0005977 61 37 1,000 0,01373121 0,06620697 ! pigment metabolic process GO:0042440 80 37 1,000 0,01373121 0,06607456 ! development of primary female sexual characteristics GO:0046545 67 38 1,000 0,01444877 0,06938872 GO:0046660|female sex differentiation, ! embryonic epithelial tube formation GO:0001838 72 38 1,000 0,01444877 0,06925049 ! glucan metabolic process GO:0044042 62 38 1,000 0,01444877 0,06911282 GO:0006073|cellular glucan metabolic process, ! mammary gland development GO:0030879 86 39 1,000 0,01518223 0,07247708 ! ear morphogenesis GO:0042471 60 39 1,000 0,01518223 0,07233356 ! organic ether metabolic process GO:0018904 55 39 1,000 0,01518223 0,07219061 ! segmentation GO:0035282 67 39 1,000 0,01518223 0,07204822 ! regulation of action potential in neuron GO:0019228 73 39 1,000 0,01518223 0,07190639 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 1,000 0,01593141 0,07530643 ! regulation of hormone secretion GO:0046883 62 40 1,000 0,01593141 0,07515877 ! negative regulation of binding GO:0051100 72 40 1,000 0,01593141 0,07501169 ! mesenchymal cell development GO:0014031 87 40 1,000 0,01593141 0,07486518 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! cytokinesis GO:0000910 72 40 1,000 0,01593141 0,07471925 ! gliogenesis GO:0042063 88 41 1,000 0,01669615 0,07815356 ! female gamete generation GO:0007292 61 41 1,000 0,01669615 0,07800181 ! dorsal/ventral pattern formation GO:0009953 68 41 1,000 0,01669615 0,07785064 ! negative regulation of protein complex disassembly GO:0043242 101 42 1,000 0,01747628 0,0813306 ! regulation of intracellular protein transport GO:0033157 80 42 1,000 0,01747628 0,08117359 ! neuron migration GO:0001764 79 42 1,000 0,01747628 0,08101718 ! regulation of protein secretion GO:0050708 71 42 1,000 0,01747628 0,08086138 ! epithelial cell differentiation GO:0030855 79 43 1,000 0,01827163 0,08437916 ! energy reserve metabolic process GO:0006112 74 43 1,000 0,01827163 0,08421752 ! biopolymer methylation GO:0043414 84 44 1,000 0,01908205 0,08778473 ! B cell differentiation GO:0030183 107 44 1,000 0,01908205 0,08761721 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 1,000 0,01908205 0,08745032 ! developmental growth GO:0048589 82 44 1,000 0,01908205 0,08728406 ! regulation of JAK-STAT cascade GO:0046425 70 45 1,000 0,01990738 0,09088643 ! detection of stimulus involved in sensory perception GO:0050906 66 45 1,000 0,01990738 0,09071429 ! branching morphogenesis of a tube GO:0048754 97 45 1,000 0,01990738 0,09054281 ! ATP synthesis coupled electron transport GO:0042773 64 45 1,000 0,01990738 0,09037198 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! regulation of nucleocytoplasmic transport GO:0046822 85 46 1,000 0,02074744 0,09400819 ! vascular process in circulatory system GO:0003018 80 47 1,000 0,0216021 0,0976967 ! regulation of adaptive immune response GO:0002819 84 47 1,000 0,0216021 0,09751341 ! methylation GO:0032259 90 47 1,000 0,0216021 0,0973308 ! protein homooligomerization GO:0051260 76 47 1,000 0,0216021 0,09714887 ! mitochondrial transport GO:0006839 82 48 1,000 0,02247118 0,10086875 ! morphogenesis of embryonic epithelium GO:0016331 91 48 1,000 0,02247118 0,10068091 ! regulation of action potential GO:0001508 95 49 1,000 0,02335453 0,10444422 ! regulation of protein complex disassembly GO:0043244 113 49 1,000 0,02335453 0,10425044 ! response to temperature stimulus GO:0009266 76 49 1,000 0,02335453 0,10405739 ! endocrine system development GO:0035270 104 49 1,000 0,02335453 0,10386505 ! detection of abiotic stimulus GO:0009582 74 49 1,000 0,02335453 0,10367341 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,02384366 0,10564983 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,02384366 0,10545562 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,02384366 0,10526212 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,02384366 0,10506934 ! neuron fate determination GO:0048664 7 5 0,000 0,02384366 0,10487725 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02384366 0,10468587 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,02384366 0,10449519 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,02384366 0,1043052 ! polyol transport GO:0015791 12 5 0,000 0,02384366 0,10411589 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,02384366 0,10392728 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,02384366 0,10373934 ! response to superoxide GO:0000303 10 5 0,000 0,02384366 0,10355209 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,02384366 0,10336551 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,02384366 0,1031796 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,02384366 0,10299436 ! female meiosis GO:0007143 7 5 0,000 0,02384366 0,10280978 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,02384366 0,10262586 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,02384366 0,1024426 ! cobalt ion transport GO:0006824 11 5 0,000 0,02384366 0,10226 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,02384366 0,10207804 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,02384366 0,10189673 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,02384366 0,10171606 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,02384366 0,10153603 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,02384366 0,10135664 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,02384366 0,10117788 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,02384366 0,10099975 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,02384366 0,10082225 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,02384366 0,10064536 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,02384366 0,1004691 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02384366 0,10029346 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,02384366 0,10011842 ! negative chemotaxis GO:0050919 14 5 0,000 0,02384366 0,099944 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,02384366 0,09977019 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,02384366 0,09959697 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,02384366 0,09942436 ! behavioral response to pain GO:0048266 9 5 0,000 0,02384366 0,09925235 ! clathrin coat assembly GO:0048268 14 5 0,000 0,02384366 0,09908093 ! Notch receptor processing GO:0007220 8 5 0,000 0,02384366 0,0989101 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02384366 0,09873986 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,02384366 0,0985702 ! micturition GO:0060073 9 5 0,000 0,02384366 0,09840113 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,02384366 0,09823263 ! copulation GO:0007620 9 5 0,000 0,02384366 0,09806471 ! glial cell fate commitment GO:0021781 13 5 0,000 0,02384366 0,09789737 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,02384366 0,09773059 ! spermidine metabolic process GO:0008216 7 5 0,000 0,02384366 0,09756438 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,02384366 0,09739874 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,02384366 0,09723366 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,02384366 0,09706913 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,02384366 0,09690516 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,02384366 0,09674175 ! grooming behavior GO:0007625 6 5 0,000 0,02384366 0,09657888 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,02384366 0,09641657 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,02384366 0,09625479 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02384366 0,09609356 ! positive regulation of glycolysis GO:0045821 14 5 0,000 0,02384366 0,09593287 ! lymph vessel development GO:0001945 10 5 0,000 0,02384366 0,09577272 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,02384366 0,0956131 ! endochondral ossification GO:0001958 16 5 0,000 0,02384366 0,09545401 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,02384366 0,09529544 ! parathyroid gland development GO:0060017 13 5 0,000 0,02384366 0,09513741 ! anagen GO:0042640 6 5 0,000 0,02384366 0,0949799 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,02384366 0,0948229 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,02384366 0,09466643 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,02384366 0,09451047 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,02384366 0,09435503 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,02384366 0,09420009 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,02384366 0,09404567 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,02384366 0,09389175 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,02384366 0,09373833 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,02384366 0,09358541 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,02384366 0,09343299 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,02384366 0,09328107 GO:0046516|hypusine metabolic process, ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,02384366 0,09312964 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,02384366 0,0929787 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,02384366 0,09282825 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,02384366 0,09267828 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,02384366 0,0925288 ! histidine catabolic process GO:0006548 6 5 0,000 0,02384366 0,0923798 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,02384366 0,09223128 ! valine metabolic process GO:0006573 10 5 0,000 0,02384366 0,09208324 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,02384366 0,09193567 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,02384366 0,09178857 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,02384366 0,09164194 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,02384366 0,09149579 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,02384366 0,09135009 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,02384366 0,09120486 ! polyol catabolic process GO:0046174 7 5 0,000 0,02384366 0,09106009 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,02384366 0,09091578 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,02384366 0,09077193 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,02384366 0,09062853 ! muscle cell migration GO:0014812 8 5 0,000 0,02384366 0,09048558 ! mitochondrial fission GO:0000266 8 5 0,000 0,02384366 0,09034308 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,02384366 0,09020103 ! mRNA transcription GO:0009299 9 5 0,000 0,02384366 0,09005943 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,02384366 0,08991827 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,02384366 0,08977755 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,02384366 0,08963728 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,02384366 0,08949744 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,02384366 0,08935803 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,02384366 0,08921906 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,02384366 0,08908052 ! response to food GO:0032094 6 5 0,000 0,02384366 0,08894241 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,02384366 0,08880473 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,02384366 0,08866748 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,02384366 0,08853064 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02384366 0,08839423 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,02384366 0,08825824 ! forebrain neuron development GO:0021884 13 5 0,000 0,02384366 0,08812267 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,02384366 0,08798751 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,02384366 0,08785277 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,02384366 0,08771844 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02384366 0,08758452 GO:0009251|glucan catabolic process, ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,02384366 0,087451 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02384366 0,0873179 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,02384366 0,08718519 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,02384366 0,08705289 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,02384366 0,086921 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,02384366 0,0867895 ! basic amino acid transport GO:0015802 11 5 0,000 0,02384366 0,0866584 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,02384366 0,08652769 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,02384366 0,08639738 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,02384366 0,08626745 ! depyrimidination GO:0045008 10 5 0,000 0,02384366 0,08613792 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,02384366 0,08600878 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02384366 0,08588003 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,02384366 0,08575166 GO:0006882|cellular zinc ion homeostasis, ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,02384366 0,08562367 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02384366 0,08549606 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,02384366 0,08536884 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,02384366 0,08524199 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,02384366 0,08511552 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,02384366 0,08498942 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,02384366 0,08486369 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02384366 0,08473834 ! response to arsenic GO:0046685 10 5 0,000 0,02384366 0,08461336 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,02384366 0,08448874 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,02384366 0,0843645 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,02384366 0,08424061 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,02384366 0,08411709 ! response to cadmium ion GO:0046686 7 5 0,000 0,02384366 0,08399393 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,02384366 0,08387114 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,02384366 0,0837487 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,02384366 0,08362661 ! decidualization GO:0046697 11 5 0,000 0,02384366 0,08350489 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,02384366 0,08338351 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,02384366 0,08326249 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,02384366 0,08314182 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,02384366 0,0830215 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,02384366 0,08290153 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,02384366 0,0827819 ! embryonic cleavage GO:0040016 6 5 0,000 0,02384366 0,08266262 ! peroxisome fission GO:0016559 5 5 0,000 0,02384366 0,08254368 ! histone demethylation GO:0016577 10 5 0,000 0,02384366 0,08242508 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,02384366 0,08230683 ! mitotic recombination GO:0006312 9 5 0,000 0,02384366 0,08218891 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,02384366 0,08207133 ! metaphase plate congression GO:0051310 7 5 0,000 0,02384366 0,08195408 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02384366 0,08183717 GO:0032374|regulation of cholesterol transport, ! enteric nervous system development GO:0048484 8 5 0,000 0,02384366 0,08172059 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,02384366 0,08160435 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,02384366 0,08148843 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,02384366 0,08137285 ! muscle cell proliferation GO:0033002 11 5 0,000 0,02384366 0,08125759 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,02384366 0,08114266 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,02384366 0,08102805 ! plasminogen activation GO:0031639 5 5 0,000 0,02384366 0,08091376 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,02384366 0,0807998 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,02384366 0,08068616 ! metaphase GO:0051323 8 5 0,000 0,02384366 0,08057283 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,02384366 0,08045983 ! cellular response to nutrient GO:0031670 8 5 0,000 0,02384366 0,08034714 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,02384366 0,08023477 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,02384366 0,08012271 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,02384366 0,08001096 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,02384366 0,07989952 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,02384366 0,0797884 ! response to redox state GO:0051775 5 5 0,000 0,02384366 0,07967758 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,02384366 0,07956707 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,02384366 0,07945687 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,02384366 0,07934697 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,02384366 0,07923737 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02384366 0,07912808 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,02384366 0,07901909 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02384366 0,0789104 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,02384366 0,078802 ! striatum development GO:0021756 9 5 0,000 0,02384366 0,07869391 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,02384366 0,07858611 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,02384366 0,0784786 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,02384366 0,07837139 ! glial cell migration GO:0008347 11 5 0,000 0,02384366 0,07826447 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,02384366 0,07815784 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,02384366 0,07805151 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,02384366 0,07794546 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,02384366 0,0778397 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,02384366 0,07773422 ! neuroprotection GO:0043526 6 5 0,000 0,02384366 0,07762904 ! neural plate development GO:0001840 8 5 0,000 0,02384366 0,07752413 ! regulation of sensory perception GO:0051931 7 5 0,000 0,02384366 0,07741951 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,02384366 0,07731517 GO:0046831|regulation of RNA export from nucleus, ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,02384366 0,07721111 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,02384366 0,07710734 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,02384366 0,07700384 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,02384366 0,07690061 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,02384366 0,07679767 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,02384366 0,076695 ! spindle assembly GO:0051225 6 5 0,000 0,02384366 0,0765926 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,02384366 0,07649048 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,02384366 0,07638863 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,02384366 0,07628704 ! drug metabolic process GO:0017144 6 5 0,000 0,02384366 0,07618573 ! organ regeneration GO:0031100 7 5 0,000 0,02384366 0,07608469 ! carnitine metabolic process GO:0009437 7 5 0,000 0,02384366 0,07598392 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,02384366 0,07588341 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,02384366 0,07578317 ! histone modification GO:0016570 91 50 1,000 0,02425199 0,07697927 ! regulation of gene expression, epigenetic GO:0040029 105 50 1,000 0,02425199 0,07687785 ! positive regulation of cytokine production GO:0001819 86 50 1,000 0,02425199 0,07677669 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 1,000 0,02516341 0,07955739 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 1,000 0,02516341 0,07945298 ! vesicle organization GO:0016050 107 51 1,000 0,02516341 0,07934885 ! regulation of cell shape GO:0008360 125 51 1,000 0,02516341 0,07924499 ! positive regulation of growth GO:0045927 90 52 1,000 0,02608864 0,08205135 ! covalent chromatin modification GO:0016569 101 52 1,000 0,02608864 0,08194423 ! morphogenesis of a branching structure GO:0001763 111 52 1,000 0,02608864 0,08183739 ! amino acid activation GO:0043038 92 52 1,000 0,02608864 0,08173083 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! synapse organization GO:0050808 85 52 1,000 0,02608864 0,08162455 ! respiratory electron transport chain GO:0022904 76 53 1,000 0,02702753 0,08445226 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 1,000 0,02702753 0,08434272 ! regulation of neuron apoptosis GO:0043523 100 53 1,000 0,02702753 0,08423347 ! activation of phospholipase C activity GO:0007202 103 54 1,000 0,02797992 0,08708886 GO:0010863|positive regulation of phospholipase C activity, ! negative regulation of cytoskeleton organization GO:0051494 124 54 1,000 0,02797992 0,08697634 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,02854421 0,08861595 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,02854421 0,08850175 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,02854421 0,08838785 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,02854421 0,08827424 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,02854421 0,08816092 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,02854421 0,08804789 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,02854421 0,08793516 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,02854421 0,08782271 ! sleep GO:0030431 13 6 0,000 0,02854421 0,08771055 ! response to oxygen radical GO:0000305 11 6 0,000 0,02854421 0,08759867 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,02854421 0,08748708 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,02854421 0,08737577 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,02854421 0,08726475 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,02854421 0,08715401 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,02854421 0,08704355 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,02854421 0,08693336 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,02854421 0,08682346 ! forebrain regionalization GO:0021871 8 6 0,000 0,02854421 0,08671384 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,02854421 0,08660449 ! male meiosis GO:0007140 7 6 0,000 0,02854421 0,08649541 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,02854421 0,08638661 ! response to zinc ion GO:0010043 9 6 0,000 0,02854421 0,08627809 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,02854421 0,08616983 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,02854421 0,08606185 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,02854421 0,08595414 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,02854421 0,0858467 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,02854421 0,08573952 ! malate metabolic process GO:0006108 11 6 0,000 0,02854421 0,08563262 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,02854421 0,08552597 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,02854421 0,0854196 ! protein refolding GO:0042026 15 6 0,000 0,02854421 0,08531349 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,02854421 0,08520764 ! opsonization GO:0008228 8 6 0,000 0,02854421 0,08510205 ! mating behavior GO:0007617 7 6 0,000 0,02854421 0,08499673 ! neuron remodeling GO:0016322 15 6 0,000 0,02854421 0,08489167 ! erythrocyte maturation GO:0043249 7 6 0,000 0,02854421 0,08478686 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,02854421 0,08468231 ! equilibrioception GO:0050957 14 6 0,000 0,02854421 0,08457803 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,02854421 0,08447399 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,02854421 0,08437022 ! photoreceptor cell development GO:0042461 10 6 0,000 0,02854421 0,0842667 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,02854421 0,08416343 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,02854421 0,08406041 ! response to interferon-gamma GO:0034341 15 6 0,000 0,02854421 0,08395765 ! toxin metabolic process GO:0009404 11 6 0,000 0,02854421 0,08385514 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,02854421 0,08375287 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,02854421 0,08365086 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,02854421 0,0835491 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,02854421 0,08344758 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,02854421 0,08334631 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,02854421 0,08324528 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,02854421 0,0831445 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,02854421 0,08304396 ! thymic T cell selection GO:0045061 12 6 0,000 0,02854421 0,08294367 ! protein lipoylation GO:0009249 10 6 0,000 0,02854421 0,08284362 ! cysteine metabolic process GO:0006534 10 6 0,000 0,02854421 0,0827438 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,02854421 0,08264423 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,02854421 0,0825449 ! glutamate catabolic process GO:0006538 10 6 0,000 0,02854421 0,08244581 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,02854421 0,08234695 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,02854421 0,08224833 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,02854421 0,08214995 ! response to pH GO:0009268 10 6 0,000 0,02854421 0,0820518 ! hyperosmotic response GO:0006972 9 6 0,000 0,02854421 0,08195389 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,02854421 0,08185621 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,02854421 0,08175876 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,02854421 0,08166154 ! urea metabolic process GO:0019627 7 6 0,000 0,02854421 0,08156456 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,02854421 0,0814678 ! neutrophil activation GO:0042119 8 6 0,000 0,02854421 0,08137128 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,02854421 0,08127498 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,02854421 0,08117891 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,02854421 0,08108307 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,02854421 0,08098745 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,02854421 0,08089206 ! neuron apoptosis GO:0051402 9 6 0,000 0,02854421 0,08079689 ! nucleoside salvage GO:0043174 9 6 0,000 0,02854421 0,08070195 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,02854421 0,08060723 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,02854421 0,08051273 ! T cell mediated immunity GO:0002456 16 6 0,000 0,02854421 0,08041845 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,02854421 0,08032439 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 0,02854421 0,08023056 ! carnitine transport GO:0015879 10 6 0,000 0,02854421 0,08013694 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,02854421 0,08004354 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,02854421 0,07995036 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,02854421 0,07985739 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,02854421 0,07976464 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,02854421 0,07967211 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,02854421 0,07957979 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,02854421 0,07948768 ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,02854421 0,07939579 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,02854421 0,07930411 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,02854421 0,07921264 ! response to UV-C GO:0010225 11 6 0,000 0,02854421 0,07912138 ! astrocyte development GO:0014002 15 6 0,000 0,02854421 0,07903033 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,02854421 0,07893949 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,02854421 0,07884886 ! interaction with symbiont GO:0051702 13 6 0,000 0,02854421 0,07875844 ! regulation of dendrite development GO:0050773 16 6 0,000 0,02854421 0,07866822 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,02854421 0,07857821 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,02854421 0,07848841 ! response to copper ion GO:0046688 10 6 0,000 0,02854421 0,07839881 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,02854421 0,07830942 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,02854421 0,07822022 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,02854421 0,07813124 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,02854421 0,07804245 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,02854421 0,07795387 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,02854421 0,07786548 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,02854421 0,0777773 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,02854421 0,07768932 ! hair follicle maturation GO:0048820 7 6 0,000 0,02854421 0,07760153 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,02854421 0,07751395 ! Schwann cell development GO:0014044 15 6 0,000 0,02854421 0,07742656 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,02854421 0,07733937 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,02854421 0,07725237 ! subpallium development GO:0021544 10 6 0,000 0,02854421 0,07716557 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,02854421 0,07707896 ! histone ubiquitination GO:0016574 8 6 0,000 0,02854421 0,07699255 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,02854421 0,07690634 ! maintenance of organ identity GO:0048496 9 6 0,000 0,02854421 0,07682031 ! G2 phase GO:0051319 16 6 0,000 0,02854421 0,07673448 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,02854421 0,07664884 ! establishment of planar polarity GO:0001736 7 6 0,000 0,02854421 0,07656339 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,02854421 0,07647813 ! membrane to membrane docking GO:0022614 14 6 0,000 0,02854421 0,07639306 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,02854421 0,07630817 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,02854421 0,07622348 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,02854421 0,07613898 ! receptor internalization GO:0031623 10 6 0,000 0,02854421 0,07605466 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,02854421 0,07597053 GO:0031272|regulation of pseudopodium assembly, ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,02854421 0,07588658 GO:0043011|myeloid dendritic cell differentiation, ! protein deubiquitination GO:0016579 14 6 0,000 0,02854421 0,07580282 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 0,02854421 0,07571925 ! protein destabilization GO:0031648 9 6 0,000 0,02854421 0,07563586 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,02854421 0,07555265 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,02854421 0,07546962 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,02854421 0,07538678 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,02854421 0,07530412 ! progesterone metabolic process GO:0042448 10 6 0,000 0,02854421 0,07522164 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,02854421 0,07513934 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,02854421 0,07505722 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,02854421 0,07497528 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,02854421 0,07489352 ! determination of adult lifespan GO:0008340 15 6 0,000 0,02854421 0,07481194 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,02854421 0,07473053 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,02854421 0,0746493 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,02854421 0,07456825 ! catecholamine transport GO:0051937 9 6 0,000 0,02854421 0,07448737 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,02854421 0,07440667 ! sensory cilium assembly GO:0035058 10 6 0,000 0,02854421 0,07432614 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,02854421 0,07424579 ! maternal placenta development GO:0001893 12 6 0,000 0,02854421 0,07416561 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,02854421 0,07408561 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,02854421 0,07400577 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,02854421 0,07392611 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,02854421 0,07384662 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,02854421 0,0737673 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,02854421 0,07368815 ! cellular polysaccharide metabolic process GO:0044264 86 55 1,000 0,02894566 0,07464444 ! positive regulation of phospholipase activity GO:0010518 104 55 1,000 0,02894566 0,07456452 ! regulation of multicellular organism growth GO:0040014 85 55 1,000 0,02894566 0,07448478 ! regulation of actin filament length GO:0030832 105 56 1,000 0,02992461 0,0769216 ! skeletal muscle fiber development GO:0048741 111 56 1,000 0,02992461 0,0768395 ! positive regulation of organelle organization GO:0010638 100 56 1,000 0,02992461 0,07675759 ! muscle fiber development GO:0048747 112 57 1,000 0,03091662 0,07921766 ! regulation of phospholipase activity GO:0010517 106 57 1,000 0,03091662 0,07913339 ! regulation of intracellular transport GO:0032386 101 57 1,000 0,03091662 0,07904929 ! positive regulation of lipase activity GO:0060193 108 58 1,000 0,03192153 0,08153207 ! positive regulation of secretion GO:0051047 95 59 1,000 0,03293922 0,08404216 ! regulation of cellular component size GO:0032535 109 59 1,000 0,03293922 0,08395313 ! skeletal system morphogenesis GO:0048705 105 59 1,000 0,03293922 0,08386429 ! establishment of organelle localization GO:0051656 109 59 1,000 0,03293922 0,08377564 ! tRNA transcription GO:0009304 14 7 0,000 0,03322227 0,08440631 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,03322227 0,08431727 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,03322227 0,08422842 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,03322227 0,08413976 ! regulation of helicase activity GO:0051095 15 7 0,000 0,03322227 0,08405128 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,03322227 0,083963 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,03322227 0,08387489 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,03322227 0,08378697 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,03322227 0,08369924 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,03322227 0,08361169 ! prostate gland development GO:0030850 13 7 0,000 0,03322227 0,08352432 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,03322227 0,08343713 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,03322227 0,08335013 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,03322227 0,0832633 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,03322227 0,08317666 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,03322227 0,0830902 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,03322227 0,08300392 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,03322227 0,08291781 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 0,03322227 0,08283189 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,03322227 0,08274614 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,03322227 0,08266057 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,03322227 0,08257518 ! glycolipid transport GO:0046836 10 7 0,000 0,03322227 0,08248996 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,03322227 0,08240492 GO:0051923|sulfation, ! neuron adhesion GO:0007158 12 7 0,000 0,03322227 0,08232005 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,03322227 0,08223536 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,03322227 0,08215084 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,03322227 0,0820665 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,03322227 0,08198233 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,03322227 0,08189833 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,03322227 0,08181451 ! pericardium development GO:0060039 14 7 0,000 0,03322227 0,08173085 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,03322227 0,08164737 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,03322227 0,08156405 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,03322227 0,08148091 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,03322227 0,08139793 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,03322227 0,08131513 ! lipoprotein transport GO:0042953 14 7 0,000 0,03322227 0,08123249 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,03322227 0,08115002 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,03322227 0,08106772 ! rhythmic behavior GO:0007622 15 7 0,000 0,03322227 0,08098558 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,03322227 0,08090362 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,03322227 0,08082181 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,03322227 0,08074017 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,03322227 0,0806587 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,03322227 0,08057739 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,03322227 0,08049625 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,03322227 0,08041526 ! mechanosensory behavior GO:0007638 14 7 0,000 0,03322227 0,08033444 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,03322227 0,08025379 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,03322227 0,08017329 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,03322227 0,08009296 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,03322227 0,08001278 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,03322227 0,07993277 ! spinal cord patterning GO:0021511 13 7 0,000 0,03322227 0,07985292 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,03322227 0,07977323 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,03322227 0,07969369 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,03322227 0,07961431 ! adrenal gland development GO:0030325 17 7 0,000 0,03322227 0,0795351 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,03322227 0,07945604 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,03322227 0,07937713 ! ovulation GO:0030728 9 7 0,000 0,03322227 0,07929838 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,03322227 0,07921979 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,03322227 0,07914136 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,03322227 0,07906308 ! microtubule nucleation GO:0007020 20 7 0,000 0,03322227 0,07898495 ! proline biosynthetic process GO:0006561 10 7 0,000 0,03322227 0,07890698 ! thyroid hormone generation GO:0006590 13 7 0,000 0,03322227 0,07882916 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,03322227 0,0787515 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,03322227 0,07867399 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,03322227 0,07859663 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,03322227 0,07851942 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,03322227 0,07844237 ! galactose metabolic process GO:0006012 13 7 0,000 0,03322227 0,07836546 ! vesicle fusion GO:0006906 17 7 0,000 0,03322227 0,07828871 ! response to dietary excess GO:0002021 8 7 0,000 0,03322227 0,07821211 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,03322227 0,07813565 ! intracellular pH reduction GO:0051452 11 7 0,000 0,03322227 0,07805935 GO:0045851|pH reduction, ! melanosome organization GO:0032438 9 7 0,000 0,03322227 0,07798319 ! purine salvage GO:0043101 10 7 0,000 0,03322227 0,07790718 ! nucleoside transport GO:0015858 8 7 0,000 0,03322227 0,07783133 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,03322227 0,07775561 ! parturition GO:0007567 14 7 0,000 0,03322227 0,07768005 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,03322227 0,07760463 ! rRNA modification GO:0000154 14 7 0,000 0,03322227 0,07752936 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,03322227 0,07745424 ! spindle checkpoint GO:0031577 15 7 0,000 0,03322227 0,07737926 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,03322227 0,07730442 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,03322227 0,07722973 ! macrophage differentiation GO:0030225 11 7 0,000 0,03322227 0,07715519 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,03322227 0,07708078 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,03322227 0,07700652 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,03322227 0,07693241 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,03322227 0,07685843 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 0,03322227 0,0767846 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,03322227 0,07671091 ! fibrinolysis GO:0042730 10 7 0,000 0,03322227 0,07663737 ! eating behavior GO:0042755 7 7 0,000 0,03322227 0,07656396 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,03322227 0,07649069 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,03322227 0,07641756 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,03322227 0,07634458 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,03322227 0,07627173 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,03322227 0,07619902 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,03322227 0,07612645 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,03322227 0,07605402 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,03322227 0,07598172 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,03322227 0,07590956 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,03322227 0,07583754 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,03322227 0,07576566 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,03322227 0,07569391 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,03322227 0,0756223 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,03322227 0,07555082 ! regulation of meiosis GO:0040020 12 7 0,000 0,03322227 0,07547948 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,03322227 0,07540828 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,03322227 0,0753372 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,03322227 0,07526626 ! oxygen homeostasis GO:0032364 12 7 0,000 0,03322227 0,07519546 ! transcription termination GO:0006353 13 7 0,000 0,03322227 0,07512479 ! response to tumor cell GO:0002347 13 7 0,000 0,03322227 0,07505425 ! regulation of respiratory burst GO:0060263 11 7 0,000 0,03322227 0,07498384 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,03322227 0,07491356 ! anaphase GO:0051322 17 7 0,000 0,03322227 0,07484342 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,03322227 0,07477341 ! axonal fasciculation GO:0007413 18 7 0,000 0,03322227 0,07470353 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,03322227 0,07463377 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,03322227 0,07456415 ! diuresis GO:0030146 12 7 0,000 0,03322227 0,07449466 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,03322227 0,0744253 ! thiamin metabolic process GO:0006772 7 7 0,000 0,03322227 0,07435607 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,03322227 0,07428696 ! antibiotic transport GO:0042891 9 7 0,000 0,03322227 0,07421799 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,03322227 0,07414914 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,03322227 0,07408042 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,03322227 0,07401183 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,03322227 0,07394336 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,03322227 0,07387502 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,03322227 0,07380681 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 10 7 0,000 0,03322227 0,07373872 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,03322227 0,07367076 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,03322227 0,07360292 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,03322227 0,07353521 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,03322227 0,07346762 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,03322227 0,07340016 ! adult feeding behavior GO:0008343 9 7 0,000 0,03322227 0,07333282 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,03322227 0,0732656 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,03322227 0,07319851 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,03322227 0,07313154 ! muscle adaptation GO:0043500 14 7 0,000 0,03322227 0,07306469 ! embryonic heart tube development GO:0035050 10 7 0,000 0,03322227 0,07299797 ! retina homeostasis GO:0001895 12 7 0,000 0,03322227 0,07293136 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,03322227 0,07286488 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,03322227 0,07279852 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,03322227 0,07273228 ! protein prenylation GO:0018342 18 7 0,000 0,03322227 0,07266616 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,03322227 0,07260016 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,03322227 0,07253428 ! camera-type eye development GO:0043010 116 60 1,000 0,03396952 0,07409852 ! response to peptide hormone stimulus GO:0043434 122 61 1,000 0,0350123 0,07630399 ! regulation of mitosis GO:0007088 105 63 1,000 0,03713473 0,08085626 GO:0051783|regulation of nuclear division, ! detection of external stimulus GO:0009581 91 63 1,000 0,03713473 0,08078315 ! steroid hormone receptor signaling pathway GO:0030518 129 63 1,000 0,03713473 0,08071018 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,03787795 0,08225123 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,03787795 0,08217706 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,03787795 0,08210302 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,03787795 0,08202912 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,03787795 0,08195536 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,03787795 0,08188172 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,03787795 0,08180822 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,03787795 0,08173485 ! meiotic prophase I GO:0007128 13 8 0,000 0,03787795 0,08166161 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,03787795 0,0815885 ! oligopeptide transport GO:0006857 15 8 0,000 0,03787795 0,08151553 ! UTP metabolic process GO:0046051 8 8 0,000 0,03787795 0,08144268 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,03787795 0,08136996 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,03787795 0,08129738 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,03787795 0,08122492 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,03787795 0,08115259 ! succinate metabolic process GO:0006105 14 8 0,000 0,03787795 0,08108039 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,03787795 0,08100832 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,03787795 0,08093637 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,03787795 0,08086456 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,03787795 0,08079287 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,03787795 0,08072131 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,03787795 0,08064987 ! reflex GO:0060004 16 8 0,000 0,03787795 0,08057857 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,03787795 0,08050738 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,03787795 0,08043633 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,03787795 0,08036539 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,03787795 0,08029459 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,03787795 0,08022391 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,03787795 0,08015335 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,03787795 0,08008292 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,03787795 0,08001261 ! astrocyte differentiation GO:0048708 18 8 0,000 0,03787795 0,07994242 ! histidine metabolic process GO:0006547 16 8 0,000 0,03787795 0,07987236 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,03787795 0,07980241 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,03787795 0,0797326 ! glycine catabolic process GO:0006546 13 8 0,000 0,03787795 0,0796629 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,03787795 0,07959333 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,03787795 0,07952387 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,03787795 0,07945454 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,03787795 0,07938533 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,03787795 0,07931624 ! macrophage activation GO:0042116 12 8 0,000 0,03787795 0,07924727 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,03787795 0,07917842 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,03787795 0,07910969 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,03787795 0,07904107 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,03787795 0,07897258 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,03787795 0,07890421 ! osteoblast development GO:0002076 16 8 0,000 0,03787795 0,07883595 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,03787795 0,07876781 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,03787795 0,07869979 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,03787795 0,07863189 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,03787795 0,0785641 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,03787795 0,07849643 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,03787795 0,07842888 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,03787795 0,07836144 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,03787795 0,07829412 ! intermediate filament organization GO:0045109 12 8 0,000 0,03787795 0,07822692 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,03787795 0,07815983 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,03787795 0,07809285 ! cellular extravasation GO:0045123 12 8 0,000 0,03787795 0,07802599 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,03787795 0,07795925 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,03787795 0,07789261 ! response to antibiotic GO:0046677 11 8 0,000 0,03787795 0,0778261 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,03787795 0,07775969 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,03787795 0,0776934 ! DNA topological change GO:0006265 12 8 0,000 0,03787795 0,07762722 ! response to tropane GO:0014073 15 8 0,000 0,03787795 0,07756116 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,03787795 0,0774952 ! melanosome transport GO:0032402 13 8 0,000 0,03787795 0,07742936 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,03787795 0,07736363 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,03787795 0,07729801 ! mast cell activation GO:0045576 14 8 0,000 0,03787795 0,07723251 ! multicellular organismal aging GO:0010259 18 8 0,000 0,03787795 0,07716711 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,03787795 0,07710183 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,03787795 0,07703665 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,03787795 0,07697159 ! nucleosome disassembly GO:0006337 14 8 0,000 0,03787795 0,07690663 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,03787795 0,07684179 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,03787795 0,07677705 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,03787795 0,07671242 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,03787795 0,0766479 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,03787795 0,07658349 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,03787795 0,07651919 ! intracellular lipid transport GO:0032365 13 8 0,000 0,03787795 0,076455 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,03787795 0,07639091 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,03787795 0,07632693 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,03787795 0,07626306 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,03787795 0,0761993 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,03787795 0,07613564 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,03787795 0,07607208 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,03787795 0,07600864 ! hormone catabolic process GO:0042447 17 8 0,000 0,03787795 0,0759453 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,03787795 0,07588206 GO:0010828|positive regulation of glucose transport, ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,03787795 0,07581893 ! ATP catabolic process GO:0006200 11 8 0,000 0,03787795 0,07575591 ! blastocyst growth GO:0001832 19 8 0,000 0,03787795 0,07569299 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,03787795 0,07563017 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,03787795 0,07556746 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,03787795 0,07550485 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,03787795 0,07544235 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,03787795 0,07537995 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,03787795 0,07531765 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,03787795 0,07525546 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,03787795 0,07519336 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,03787795 0,07513137 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,03787795 0,07506949 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,03787795 0,0750077 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,03787795 0,07494602 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,03787795 0,07488444 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,03787795 0,07482295 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,03787795 0,07476157 GO:0000076|DNA replication checkpoint, ! NAD biosynthetic process GO:0009435 13 8 0,000 0,03787795 0,07470029 ! multicellular organism reproduction GO:0032504 111 64 1,000 0,0382141 0,07530149 GO:0048609|reproductive process in a multicellular organism, ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 1,000 0,0382141 0,07523987 ! secondary metabolic process GO:0019748 116 66 1,000 0,04040844 0,07949526 ! cell projection assembly GO:0030031 120 66 1,000 0,04040844 0,07943031 ! chromosome segregation GO:0007059 113 67 1,000 0,04152314 0,08155483 ! positive regulation of T cell activation GO:0050870 109 67 1,000 0,04152314 0,08148831 ! adaptive immune response GO:0002250 119 67 1,000 0,04152314 0,0814219 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! regulation of developmental growth GO:0048638 15 9 0,000 0,04251138 0,08329183 ! axon extension GO:0048675 15 9 0,000 0,04251138 0,08322406 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,04251138 0,0831564 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,04251138 0,08308885 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,04251138 0,0830214 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,04251138 0,08295407 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,04251138 0,08288685 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,04251138 0,08281973 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,04251138 0,08275273 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,04251138 0,08268583 ! phosphate transport GO:0006817 19 9 0,000 0,04251138 0,08261904 ! reproductive behavior GO:0019098 19 9 0,000 0,04251138 0,08255236 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,04251138 0,08248578 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,04251138 0,08241932 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,04251138 0,08235296 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,04251138 0,0822867 ! GTP metabolic process GO:0046039 9 9 0,000 0,04251138 0,08222055 ! RNA methylation GO:0001510 15 9 0,000 0,04251138 0,08215451 ! elastic fiber assembly GO:0048251 15 9 0,000 0,04251138 0,08208858 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,04251138 0,08202275 ! artery development GO:0060840 24 9 0,000 0,04251138 0,08195703 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,04251138 0,08189141 ! regulation of glycolysis GO:0006110 21 9 0,000 0,04251138 0,0818259 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,04251138 0,08176049 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,04251138 0,08169518 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,04251138 0,08162998 ! chemosensory behavior GO:0007635 20 9 0,000 0,04251138 0,08156489 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,04251138 0,0814999 ! leukocyte degranulation GO:0043299 16 9 0,000 0,04251138 0,08143501 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,04251138 0,08137022 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,04251138 0,08130554 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,04251138 0,08124096 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,04251138 0,08117648 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,04251138 0,08111211 ! protein targeting to ER GO:0045047 22 9 0,000 0,04251138 0,08104784 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,04251138 0,08098367 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,04251138 0,0809196 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 0,000 0,04251138 0,08085563 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,04251138 0,08079176 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,04251138 0,080728 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,04251138 0,08066433 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,04251138 0,08060076 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,04251138 0,0805373 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,04251138 0,08047393 ! mannose metabolic process GO:0006013 13 9 0,000 0,04251138 0,08041067 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,04251138 0,0803475 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,04251138 0,08028444 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,04251138 0,08022147 ! receptor clustering GO:0043113 18 9 0,000 0,04251138 0,0801586 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,04251138 0,08009583 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,04251138 0,08003315 ! ruffle organization GO:0031529 15 9 0,000 0,04251138 0,07997058 ! retinol metabolic process GO:0042572 18 9 0,000 0,04251138 0,0799081 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,04251138 0,07984572 ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,04251138 0,07978344 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,04251138 0,07972126 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,04251138 0,07965917 GO:0030204|chondroitin sulfate metabolic process, ! protein heterooligomerization GO:0051291 16 9 0,000 0,04251138 0,07959718 ! oligodendrocyte development GO:0014003 10 9 0,000 0,04251138 0,07953528 ! segment specification GO:0007379 13 9 0,000 0,04251138 0,07947348 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,04251138 0,07941178 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,04251138 0,07935017 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,04251138 0,07928866 ! response to amine stimulus GO:0014075 13 9 0,000 0,04251138 0,07922724 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,04251138 0,07916592 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,04251138 0,07910469 ! erythrocyte development GO:0048821 15 9 0,000 0,04251138 0,07904356 ! gas homeostasis GO:0033483 16 9 0,000 0,04251138 0,07898253 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,04251138 0,07892158 ! renal water homeostasis GO:0003091 14 9 0,000 0,04251138 0,07886073 ! postreplication repair GO:0006301 22 9 0,000 0,04251138 0,07879998 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,04251138 0,07873932 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,04251138 0,07867875 ! icosanoid secretion GO:0032309 15 9 0,000 0,04251138 0,07861827 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,04251138 0,07855789 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,04251138 0,0784976 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,04251138 0,0784374 ! regulation of cell division GO:0051302 15 9 0,000 0,04251138 0,0783773 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,04251138 0,07831728 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,04251138 0,07825736 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,04251138 0,07819753 ! sterol catabolic process GO:0016127 11 9 0,000 0,04251138 0,07813779 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,04251138 0,07807815 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,04251138 0,07801859 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,04251138 0,07795912 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,04251138 0,07789975 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,04251138 0,07784046 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,04251138 0,07778127 ! musculoskeletal movement GO:0050881 14 9 0,000 0,04251138 0,07772217 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,04251138 0,07766315 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,04251138 0,07760423 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,04251138 0,07754539 ! purine base metabolic process GO:0006144 21 9 0,000 0,04251138 0,07748664 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,04251138 0,07742799 ! pigment granule transport GO:0051904 17 9 0,000 0,04251138 0,07736942 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,04251138 0,07731094 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,04251138 0,07725255 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,04251138 0,07719424 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,04251138 0,07713603 ! mitochondrion localization GO:0051646 15 9 0,000 0,04251138 0,0770779 ! amino acid transport GO:0006865 125 68 1,000 0,04264934 0,07726982 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 1,000 0,04264934 0,07721168 ! regulation of lipase activity GO:0060191 130 68 1,000 0,04264934 0,07715362 ! cell cycle checkpoint GO:0000075 137 69 1,000 0,04378692 0,07915201 ! B cell activation GO:0042113 160 71 1,000 0,04609564 0,08326284 ! regulation of MAPKKK cascade GO:0043408 142 71 1,000 0,04609564 0,08320038 ! regulation of immune effector process GO:0002697 137 71 1,000 0,04609564 0,08313801 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,04712264 0,08492664 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,04712264 0,08486307 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,04712264 0,0847996 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,04712264 0,08473622 ! synapsis GO:0007129 13 10 0,000 0,04712264 0,08467294 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,04712264 0,08460975 ! N-glycan processing GO:0006491 20 10 0,000 0,04712264 0,08454666 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,04712264 0,08448365 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,04712264 0,08442075 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,04712264 0,08435794 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,04712264 0,08429522 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,04712264 0,08423259 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,04712264 0,08417006 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,04712264 0,08410761 ! androgen metabolic process GO:0008209 17 10 0,000 0,04712264 0,08404527 ! phospholipid efflux GO:0033700 16 10 0,000 0,04712264 0,08398301 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,04712264 0,08392085 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,04712264 0,08385878 ! pathogenesis GO:0009405 13 10 0,000 0,04712264 0,0837968 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,04712264 0,08373491 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,04712264 0,08367311 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,04712264 0,0836114 ! endoderm development GO:0007492 16 10 0,000 0,04712264 0,08354979 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,04712264 0,08348827 ! arginine catabolic process GO:0006527 13 10 0,000 0,04712264 0,08342683 ! proline metabolic process GO:0006560 13 10 0,000 0,04712264 0,08336549 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,04712264 0,08330424 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,04712264 0,08324307 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,04712264 0,083182 ! V(D)J recombination GO:0033151 28 10 0,000 0,04712264 0,08312102 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,04712264 0,08306012 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,04712264 0,08299932 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,04712264 0,0829386 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,04712264 0,08287797 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,04712264 0,08281743 ! multicellular organism growth GO:0035264 18 10 0,000 0,04712264 0,08275698 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,04712264 0,08269662 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,04712264 0,08263634 ! epithelial cell development GO:0002064 20 10 0,000 0,04712264 0,08257616 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,04712264 0,08251606 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,04712264 0,08245605 ! macroautophagy GO:0016236 17 10 0,000 0,04712264 0,08239612 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,04712264 0,08233629 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,04712264 0,08227653 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,04712264 0,08221687 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,04712264 0,08215729 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 0,04712264 0,0820978 ! copper ion homeostasis GO:0055070 13 10 0,000 0,04712264 0,0820384 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,04712264 0,08197908 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,04712264 0,08191984 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,04712264 0,0818607 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,04712264 0,08180163 ! blastoderm segmentation GO:0007350 18 10 0,000 0,04712264 0,08174266 ! response to dsRNA GO:0043331 20 10 0,000 0,04712264 0,08168376 ! DNA ligation GO:0006266 19 10 0,000 0,04712264 0,08162496 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,04712264 0,08156623 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,04712264 0,0815076 ! melanosome localization GO:0032400 16 10 0,000 0,04712264 0,08144904 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,04712264 0,08139057 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,04712264 0,08133218 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,04712264 0,08127388 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,04712264 0,08121566 ! mRNA cleavage GO:0006379 17 10 0,000 0,04712264 0,08115753 ! protein sumoylation GO:0016925 15 10 0,000 0,04712264 0,08109947 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,04712264 0,0810415 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,04712264 0,08098362 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,04712264 0,08092581 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,04712264 0,08086809 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,04712264 0,08081045 ! prophase GO:0051324 15 10 0,000 0,04712264 0,0807529 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,04712264 0,08069542 ! apical protein localization GO:0045176 15 10 0,000 0,04712264 0,08063803 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,04712264 0,08058071 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,04712264 0,08052348 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,04712264 0,08046633 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,04712264 0,08040927 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,04712264 0,08035228 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,04712264 0,08029537 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,04712264 0,08023855 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,04712264 0,0801818 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 0,04712264 0,08012513 GO:0043470|regulation of carbohydrate catabolic process, ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,04712264 0,08006855 ! blastocyst formation GO:0001825 17 10 0,000 0,04712264 0,08001204 ! cerebellar cortex development GO:0021695 15 10 0,000 0,04712264 0,07995562 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,04712264 0,07989927 ! activation of innate immune response GO:0002218 12 10 0,000 0,04712264 0,079843 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,04712264 0,07978682 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,04712264 0,07973071 ! establishment of cell polarity GO:0030010 16 10 0,000 0,04712264 0,07967468 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,04712264 0,07961873 ! acute inflammatory response GO:0002526 113 72 1,000 0,04726652 0,07980579 ! learning or memory GO:0007611 147 73 1,000 0,04844824 0,08174367 ! axon guidance GO:0007411 139 73 1,000 0,04844824 0,08168638 ! meiosis GO:0007126 121 74 1,000 0,04964067 0,08363828 GO:0051327|M phase of meiotic cell cycle, ! regulation of actin cytoskeleton organization GO:0032956 149 74 1,000 0,04964067 0,08357975 ! leukocyte mediated immunity GO:0002443 128 74 1,000 0,04964067 0,0835213 ! organelle localization GO:0051640 136 74 1,000 0,04964067 0,08346294 ! cell-matrix adhesion GO:0007160 163 75 1,000 0,05084369 0,08542592 ! phosphoinositide-mediated signaling GO:0048015 131 75 1,000 0,05084369 0,0853663 ! regulation of vesicle-mediated transport GO:0060627 119 75 1,000 0,05084369 0,08530677 ! meiotic cell cycle GO:0051321 122 75 1,000 0,05084369 0,08524733 ! rhythmic process GO:0048511 128 75 1,000 0,05084369 0,08518796 ! respiratory burst GO:0045730 17 11 0,000 0,05171184 0,08658225 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,05171184 0,08652204 ! neuron fate specification GO:0048665 17 11 0,000 0,05171184 0,08646191 ! telencephalon cell migration GO:0022029 20 11 0,000 0,05171184 0,08640187 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,05171184 0,08634191 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,05171184 0,08628203 ! thyroid gland development GO:0030878 26 11 0,000 0,05171184 0,08622224 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,05171184 0,08616253 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,05171184 0,0861029 ! response to pain GO:0048265 24 11 0,000 0,05171184 0,08604336 ! T cell proliferation GO:0042098 26 11 0,000 0,05171184 0,08598389 ! bone resorption GO:0045453 16 11 0,000 0,05171184 0,08592451 ! ventral spinal cord development GO:0021517 21 11 0,000 0,05171184 0,08586521 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,05171184 0,085806 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,05171184 0,08574686 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,05171184 0,08568781 ! melanocyte differentiation GO:0030318 21 11 0,000 0,05171184 0,08562883 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,05171184 0,08556994 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,05171184 0,08551113 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,05171184 0,0854524 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,05171184 0,08539375 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,05171184 0,08533518 ! lipid digestion GO:0044241 18 11 0,000 0,05171184 0,08527669 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,05171184 0,08521828 ! UV protection GO:0009650 19 11 0,000 0,05171184 0,08515995 ! adult heart development GO:0007512 14 11 0,000 0,05171184 0,08510171 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,05171184 0,08504354 ! temperature homeostasis GO:0001659 17 11 0,000 0,05171184 0,08498545 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,05171184 0,08492744 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,05171184 0,0848695 ! regulation of organ growth GO:0046620 13 11 0,000 0,05171184 0,08481165 ! pigment granule localization GO:0051875 20 11 0,000 0,05171184 0,08475388 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,05171184 0,08469618 ! vasoconstriction GO:0042310 18 11 0,000 0,05171184 0,08463857 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,05171184 0,08458103 ! embryonic axis specification GO:0000578 18 11 0,000 0,05171184 0,08452357 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,05171184 0,08446619 ! snRNA metabolic process GO:0016073 24 11 0,000 0,05171184 0,08440888 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,05171184 0,08435166 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,05171184 0,08429451 GO:0006809|nitric oxide biosynthetic process, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,05171184 0,08423744 ! zymogen activation GO:0031638 15 11 0,000 0,05171184 0,08418044 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,05171184 0,08412353 ! neuroblast proliferation GO:0007405 24 11 0,000 0,05171184 0,08406668 ! nucleosome positioning GO:0016584 15 11 0,000 0,05171184 0,08400992 ! regulation of isotype switching GO:0045191 22 11 0,000 0,05171184 0,08395323 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,05171184 0,08389662 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,05171184 0,08384009 ! acid secretion GO:0046717 18 11 0,000 0,05171184 0,08378363 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,05171184 0,08372725 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,05171184 0,08367094 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,05171184 0,08361471 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,05171184 0,08355856 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! cholesterol efflux GO:0033344 19 11 0,000 0,05171184 0,08350248 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,05171184 0,08344647 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,05171184 0,08339055 ! germ cell migration GO:0008354 25 11 0,000 0,05171184 0,08333469 ! embryonic gut development GO:0048566 15 11 0,000 0,05171184 0,08327891 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,05171184 0,08322321 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,05171184 0,08316758 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,05171184 0,08311202 ! defense response to fungus GO:0050832 13 11 0,000 0,05171184 0,08305654 ! developmental induction GO:0031128 19 11 0,000 0,05171184 0,08300113 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,05171184 0,0829458 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,05171184 0,08289054 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,05171184 0,08283535 ! sequestering of metal ion GO:0051238 14 11 0,000 0,05171184 0,08278024 ! lamellipodium assembly GO:0030032 20 11 0,000 0,05171184 0,0827252 ! regulation of embryonic development GO:0045995 27 11 0,000 0,05171184 0,08267023 ! nucleus localization GO:0051647 19 11 0,000 0,05171184 0,08261533 ! regulation of synapse organization GO:0050807 17 11 0,000 0,05171184 0,08256051 ! defense response to bacterium GO:0042742 89 76 1,000 0,05205716 0,08305671 ! regulation of actin filament-based process GO:0032970 152 77 1,000 0,05328095 0,08495292 ! protein oligomerization GO:0051259 139 78 1,000 0,05451494 0,08686288 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,0562791 0,0896145 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,0562791 0,08955523 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,0562791 0,08949604 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 0,0562791 0,08943693 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,0562791 0,08937789 ! virus-host interaction GO:0019048 29 12 0,000 0,0562791 0,08931894 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,0562791 0,08926006 ! cartilage condensation GO:0001502 20 12 0,000 0,0562791 0,08920126 ! mating GO:0007618 17 12 0,000 0,0562791 0,08914253 ! protein complex disassembly GO:0043241 27 12 0,000 0,0562791 0,08908389 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,0562791 0,08902532 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,0562791 0,08896683 ! hippocampus development GO:0021766 26 12 0,000 0,0562791 0,08890841 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 0,0562791 0,08885007 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,0562791 0,08879181 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,0562791 0,08873362 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,0562791 0,08867551 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,0562791 0,08861748 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,0562791 0,08855952 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,0562791 0,08850164 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,0562791 0,08844383 ! drug transport GO:0015893 16 12 0,000 0,0562791 0,0883861 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,0562791 0,08832845 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,0562791 0,08827087 ! polyamine metabolic process GO:0006595 17 12 0,000 0,0562791 0,08821336 ! mitotic spindle organization GO:0007052 21 12 0,000 0,0562791 0,08815593 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,0562791 0,08809857 ! forebrain cell migration GO:0021885 21 12 0,000 0,0562791 0,08804129 ! asymmetric protein localization GO:0008105 20 12 0,000 0,0562791 0,08798409 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,0562791 0,08792695 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,0562791 0,0878699 ! entry into host cell GO:0030260 32 12 0,000 0,0562791 0,08781291 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! monoamine transport GO:0015844 18 12 0,000 0,0562791 0,087756 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,0562791 0,08769916 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,0562791 0,0876424 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,0562791 0,08758571 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,0562791 0,08752909 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,0562791 0,08747255 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,0562791 0,08741608 ! protein homotetramerization GO:0051289 21 12 0,000 0,0562791 0,08735968 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,0562791 0,08730336 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,0562791 0,08724711 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,0562791 0,08719093 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,0562791 0,08713482 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,0562791 0,08707878 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,0562791 0,08702282 ! cranial nerve development GO:0021545 20 12 0,000 0,0562791 0,08696693 ! fucose catabolic process GO:0019317 22 12 0,000 0,0562791 0,08691111 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,0562791 0,08685536 ! histone methylation GO:0016571 26 12 0,000 0,0562791 0,08679969 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,0562791 0,08674408 ! autonomic nervous system development GO:0048483 24 12 0,000 0,0562791 0,08668855 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,0562791 0,08663308 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,0562791 0,08657769 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,0562791 0,08652237 ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,0562791 0,08646712 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,0562791 0,08641194 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,0562791 0,08635683 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,0562791 0,08630179 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,0562791 0,08624682 ! response to cold GO:0009409 17 12 0,000 0,0562791 0,08619192 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,0562791 0,08613709 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,0562791 0,08608233 ! cellular lipid catabolic process GO:0044242 134 80 1,000 0,05701303 0,08714953 ! protein import into nucleus GO:0006606 158 80 1,000 0,05701303 0,08709419 ! cell-substrate adhesion GO:0031589 171 81 1,000 0,05827688 0,08896838 ! intracellular protein transmembrane transport GO:0065002 153 81 1,000 0,05827688 0,08891197 ! nuclear import GO:0051170 161 81 1,000 0,05827688 0,08885562 ! regulation of neuron differentiation GO:0045664 167 81 1,000 0,05827688 0,08879935 ! response to nutrient GO:0007584 125 82 1,000 0,05955043 0,09068249 ! cGMP metabolic process GO:0046068 18 13 0,000 0,06082451 0,09256405 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,06082451 0,09250554 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,06082451 0,0924471 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,06082451 0,09238874 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,06082451 0,09233045 ! lipid localization GO:0010876 28 13 0,000 0,06082451 0,09227223 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,06082451 0,09221409 ! organelle fusion GO:0048284 32 13 0,000 0,06082451 0,09215602 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,06082451 0,09209803 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,06082451 0,0920401 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,06082451 0,09198225 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,06082451 0,09192447 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,06082451 0,09186677 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,06082451 0,09180914 ! methionine metabolic process GO:0006555 27 13 0,000 0,06082451 0,09175158 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,06082451 0,09169409 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,06082451 0,09163667 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,06082451 0,09157933 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cell-cell junction assembly GO:0007043 27 13 0,000 0,06082451 0,09152205 ! response to X-ray GO:0010165 25 13 0,000 0,06082451 0,09146485 ! cytokine metabolic process GO:0042107 22 13 0,000 0,06082451 0,09140772 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,06082451 0,09135066 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 0,06082451 0,09129368 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,06082451 0,09123676 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,06082451 0,09117991 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,06082451 0,09112314 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,06082451 0,09106644 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,06082451 0,0910098 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,06082451 0,09095324 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,06082451 0,09089675 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,06082451 0,09084032 ! regulation of cellular pH GO:0030641 22 13 0,000 0,06082451 0,09078397 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,06082451 0,09072769 ! ribosome assembly GO:0042255 17 13 0,000 0,06082451 0,09067148 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,06082451 0,09061533 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,06082451 0,09055926 ! chromatin silencing GO:0006342 26 13 0,000 0,06082451 0,09050325 ! regulation of epidermis development GO:0045682 19 13 0,000 0,06082451 0,09044732 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,06082451 0,09039145 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,06082451 0,09033566 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,06082451 0,09027993 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,06082451 0,09022427 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,06082451 0,09016868 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,06082451 0,09011315 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,06082451 0,0900577 ! embryonic placenta development GO:0001892 23 13 0,000 0,06082451 0,09000231 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,06082451 0,089947 ! insulin secretion GO:0030073 23 13 0,000 0,06082451 0,08989175 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,06082451 0,08983656 ! acrosome reaction GO:0007340 18 13 0,000 0,06082451 0,08978145 ! one-carbon metabolic process GO:0006730 154 85 1,000 0,06342812 0,09356717 ! oxidative phosphorylation GO:0006119 133 86 1,000 0,06473929 0,09544285 ! amine transport GO:0015837 155 86 1,000 0,06473929 0,09538441 ! rRNA transcription GO:0009303 25 14 0,000 0,06534817 0,09622259 ! lactation GO:0007595 26 14 0,000 0,06534817 0,09616373 ! reproductive cellular process GO:0048610 20 14 0,000 0,06534817 0,09610495 ! tRNA modification GO:0006400 20 14 0,000 0,06534817 0,09604625 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,06534817 0,09598761 ! regulation of S phase GO:0033261 23 14 0,000 0,06534817 0,09592904 ! water transport GO:0006833 21 14 0,000 0,06534817 0,09587055 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,06534817 0,09581213 ! non-recombinational repair GO:0000726 25 14 0,000 0,06534817 0,09575378 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,06534817 0,0956955 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,06534817 0,09563729 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,06534817 0,09557915 ! RNA polyadenylation GO:0043631 30 14 0,000 0,06534817 0,09552108 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,06534817 0,09546309 ! palate development GO:0060021 31 14 0,000 0,06534817 0,09540516 ! regulated secretory pathway GO:0045055 23 14 0,000 0,06534817 0,0953473 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,06534817 0,09528952 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,06534817 0,0952318 ! arginine metabolic process GO:0006525 17 14 0,000 0,06534817 0,09517415 ! regulation of heart rate GO:0002027 24 14 0,000 0,06534817 0,09511658 ! organic alcohol transport GO:0015850 29 14 0,000 0,06534817 0,09505907 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,06534817 0,09500163 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,06534817 0,09494427 ! embryo implantation GO:0007566 30 14 0,000 0,06534817 0,09488697 ! neutral amino acid transport GO:0015804 26 14 0,000 0,06534817 0,09482974 ! L-amino acid transport GO:0015807 30 14 0,000 0,06534817 0,09477258 ! bone mineralization GO:0030282 17 14 0,000 0,06534817 0,09471548 ! stem cell development GO:0048864 43 14 0,000 0,06534817 0,09465846 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,06534817 0,09460151 ! cerebellum development GO:0021549 21 14 0,000 0,06534817 0,09454462 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,06534817 0,0944878 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,06534817 0,09443105 ! cofactor transport GO:0051181 26 14 0,000 0,06534817 0,09437437 ! NADP metabolic process GO:0006739 24 14 0,000 0,06534817 0,09431776 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,06534817 0,09426121 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,06534817 0,09420474 ! intestinal absorption GO:0050892 25 14 0,000 0,06534817 0,09414833 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,06534817 0,09409198 ! oxygen transport GO:0015671 21 14 0,000 0,06534817 0,09403571 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,06534817 0,0939795 ! male genitalia development GO:0030539 24 14 0,000 0,06534817 0,09392336 ! regulation of axon extension GO:0030516 37 14 0,000 0,06534817 0,09386729 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,06534817 0,09381128 ! protein localization in nucleus GO:0034504 176 87 1,000 0,06605957 0,09477599 ! cellular respiration GO:0045333 135 88 1,000 0,06738885 0,09662549 ! cellular defense response GO:0006968 114 89 1,000 0,068727 0,0984855 ! regulation of cell morphogenesis GO:0022604 215 89 1,000 0,068727 0,09842688 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,0698502 0,09997596 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,0698502 0,09991652 ! superoxide anion generation GO:0042554 20 15 0,000 0,0698502 0,09985715 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,0698502 0,09979785 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,0698502 0,09973862 ! copper ion transport GO:0006825 20 15 0,000 0,0698502 0,09967947 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,0698502 0,09962038 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,0698502 0,09956136 ! sulfate transport GO:0008272 23 15 0,000 0,0698502 0,09950242 ! response to cAMP GO:0051591 22 15 0,000 0,0698502 0,09944354 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,0698502 0,09938473 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,0698502 0,09932599 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,0698502 0,09926732 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,0698502 0,09920873 ! response to hexose stimulus GO:0009746 22 15 0,000 0,0698502 0,0991502 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,0698502 0,09909173 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,0698502 0,09903334 ! pituitary gland development GO:0021983 29 15 0,000 0,0698502 0,09897502 ! vesicle coating GO:0006901 33 15 0,000 0,0698502 0,09891676 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,0698502 0,09885858 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,0698502 0,09880046 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,0698502 0,09874241 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,0698502 0,09868443 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,0698502 0,09862651 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,0698502 0,09856867 ! regulation of vasodilation GO:0042312 26 15 0,000 0,0698502 0,09851089 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,0698502 0,09845318 ! histone deacetylation GO:0016575 20 15 0,000 0,0698502 0,09839554 ! mRNA splice site selection GO:0006376 38 15 0,000 0,0698502 0,09833796 ! tissue regeneration GO:0042246 26 15 0,000 0,0698502 0,09828046 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,0698502 0,09822302 ! water homeostasis GO:0030104 27 15 0,000 0,0698502 0,09816564 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,0698502 0,09810834 ! muscle maintenance GO:0046716 26 15 0,000 0,0698502 0,0980511 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,0698502 0,09799392 ! dopamine metabolic process GO:0042417 35 15 0,000 0,0698502 0,09793682 ! heme biosynthetic process GO:0006783 29 15 0,000 0,0698502 0,09787978 ! cell killing GO:0001906 29 15 0,000 0,0698502 0,09782281 ! detection of bacterium GO:0016045 18 15 0,000 0,0698502 0,0977659 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,0698502 0,09770906 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,0698502 0,09765228 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,0698502 0,09759558 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,0698502 0,09753893 ! peptide hormone processing GO:0016486 23 15 0,000 0,0698502 0,09748236 ! response to protein stimulus GO:0051789 149 91 1,000 0,07142947 0,09962858 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,07433069 0,10361509 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,07433069 0,10355509 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,07433069 0,10349516 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,07433069 0,1034353 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,07433069 0,10337551 ! bone remodeling GO:0046849 27 16 0,000 0,07433069 0,10331579 ! filopodium assembly GO:0046847 32 16 0,000 0,07433069 0,10325614 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,07433069 0,10319656 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,07433069 0,10313705 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,07433069 0,1030776 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,07433069 0,10301823 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,07433069 0,10295892 ! startle response GO:0001964 28 16 0,000 0,07433069 0,10289968 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,07433069 0,10284051 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,07433069 0,1027814 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,07433069 0,10272237 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,07433069 0,1026634 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,07433069 0,1026045 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,07433069 0,10254567 ! protein polyubiquitination GO:0000209 34 16 0,000 0,07433069 0,1024869 ! glutamate metabolic process GO:0006536 22 16 0,000 0,07433069 0,1024282 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,07433069 0,10236957 ! response to osmotic stress GO:0006970 25 16 0,000 0,07433069 0,10231101 ! lysosomal transport GO:0007041 26 16 0,000 0,07433069 0,10225251 ! fructose metabolic process GO:0006000 25 16 0,000 0,07433069 0,10219408 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,07433069 0,10213572 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,07433069 0,10207742 ! intermediate filament-based process GO:0045103 32 16 0,000 0,07433069 0,10201919 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,07433069 0,10196103 ! negative regulation of immune response GO:0050777 35 16 0,000 0,07433069 0,10190293 ! axon cargo transport GO:0008088 43 16 0,000 0,07433069 0,1018449 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,07433069 0,10178693 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,07433069 0,10172903 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 0,07433069 0,1016712 ! DNA replication initiation GO:0006270 27 16 0,000 0,07433069 0,10161343 ! neuron recognition GO:0008038 35 16 0,000 0,07433069 0,10155573 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,07433069 0,10149809 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,07433069 0,10144052 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,07433069 0,10138302 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,07433069 0,10132558 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,07433069 0,1012682 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,07433069 0,10121089 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,07433069 0,10115364 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,07433069 0,10109646 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,07433069 0,10103934 ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,07433069 0,10098229 ! female pregnancy GO:0007565 164 94 1,000 0,0755469 0,10257666 ! transcription initiation GO:0006352 153 94 1,000 0,0755469 0,10251881 ! mRNA transport GO:0051028 169 96 1,000 0,07833304 0,10623974 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,07878975 0,10679895 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,07878975 0,10673881 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,07878975 0,10667874 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,07878975 0,10661875 ! signal complex assembly GO:0007172 41 17 0,000 0,07878975 0,10655881 ! endothelial cell migration GO:0043542 28 17 0,000 0,07878975 0,10649895 ! inositol metabolic process GO:0006020 28 17 0,000 0,07878975 0,10643915 ! gene silencing by RNA GO:0031047 36 17 0,000 0,07878975 0,10637942 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,07878975 0,10631976 ! glial cell development GO:0021782 27 17 0,000 0,07878975 0,10626016 ! limbic system development GO:0021761 36 17 0,000 0,07878975 0,10620063 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,07878975 0,10614117 ! adult walking behavior GO:0007628 33 17 0,000 0,07878975 0,10608177 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,07878975 0,10602244 ! heart looping GO:0001947 30 17 0,000 0,07878975 0,10596318 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,07878975 0,10590398 ! myoblast differentiation GO:0045445 45 17 0,000 0,07878975 0,10584485 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,07878975 0,10578579 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,07878975 0,10572679 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,07878975 0,10566785 ! glycine metabolic process GO:0006544 28 17 0,000 0,07878975 0,10560899 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,07878975 0,10555018 ! NAD metabolic process GO:0019674 29 17 0,000 0,07878975 0,10549145 ! membrane budding GO:0006900 37 17 0,000 0,07878975 0,10543278 ! DNA integration GO:0015074 29 17 0,000 0,07878975 0,10537417 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,07878975 0,10531563 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,07878975 0,10525715 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,07878975 0,10519874 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,07878975 0,10514039 ! genitalia development GO:0048806 30 17 0,000 0,07878975 0,10508211 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,07878975 0,10502389 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,07878975 0,10496574 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,07878975 0,10490765 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,07878975 0,10484963 ! steroid catabolic process GO:0006706 31 17 0,000 0,07878975 0,10479167 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,07878975 0,10473377 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,07878975 0,10467594 ! gas transport GO:0015669 25 17 0,000 0,07878975 0,10461817 ! organic cation transport GO:0015695 31 17 0,000 0,07878975 0,10456047 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,07878975 0,10450283 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,07878975 0,10444525 ! microspike assembly GO:0030035 36 17 0,000 0,07878975 0,10438774 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,07878975 0,10433029 ! regulation of DNA metabolic process GO:0051052 178 97 1,000 0,07973814 0,10552803 ! protein ubiquitination GO:0016567 217 97 1,000 0,07973814 0,10547002 ! Golgi vesicle transport GO:0048193 207 99 1,000 0,08257184 0,10915816 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,08322747 0,10996447 ! neuron maturation GO:0042551 42 18 0,000 0,08322747 0,10990411 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,08322747 0,10984383 ! phosphoinositide phosphorylation GO:0046854 33 18 0,000 0,08322747 0,1097836 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,08322747 0,10972345 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,08322747 0,10966336 ! memory GO:0007613 31 18 0,000 0,08322747 0,10960333 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,08322747 0,10954338 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,08322747 0,10948348 ! patterning of blood vessels GO:0001569 39 18 0,000 0,08322747 0,10942366 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,08322747 0,1093639 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,08322747 0,1093042 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,08322747 0,10924457 ! glutamine metabolic process GO:0006541 29 18 0,000 0,08322747 0,109185 ! response to retinoic acid GO:0032526 26 18 0,000 0,08322747 0,1091255 ! response to fungus GO:0009620 21 18 0,000 0,08322747 0,10906606 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,08322747 0,10900669 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,08322747 0,10894738 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,08322747 0,10888814 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,08322747 0,10882896 ! vitamin transport GO:0051180 27 18 0,000 0,08322747 0,10876985 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,08322747 0,1087108 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,08322747 0,10865181 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,08322747 0,10859289 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,08322747 0,10853403 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,08322747 0,10847524 ! nerve development GO:0021675 28 18 0,000 0,08322747 0,10841651 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,08322747 0,10835784 ! protein secretion GO:0009306 39 19 0,000 0,08764396 0,11404617 ! negative regulation of defense response GO:0031348 25 19 0,000 0,08764396 0,11398453 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,08764396 0,11392295 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,08764396 0,11386143 ! skin development GO:0043588 36 19 0,000 0,08764396 0,11379999 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,08764396 0,11373861 ! lipid phosphorylation GO:0046834 35 19 0,000 0,08764396 0,11367729 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,08764396 0,11361604 ! bile acid metabolic process GO:0008206 29 19 0,000 0,08764396 0,11355486 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,08764396 0,11349374 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,08764396 0,11343269 ! cerebral cortex development GO:0021987 36 19 0,000 0,08764396 0,11337171 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,08764396 0,11331079 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,08764396 0,11324993 ! heme metabolic process GO:0042168 36 19 0,000 0,08764396 0,11318914 ! actin filament bundle formation GO:0051017 42 19 0,000 0,08764396 0,11312842 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,08764396 0,11306776 ! plasma membrane fusion GO:0045026 28 19 0,000 0,08764396 0,11300717 ! peptide cross-linking GO:0018149 37 19 0,000 0,08764396 0,11294664 ! protein export from nucleus GO:0006611 36 19 0,000 0,08764396 0,11288617 ! heart process GO:0003015 30 19 0,000 0,08764396 0,11282578 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,08764396 0,11276544 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,08764396 0,11270517 ! visual learning GO:0008542 36 19 0,000 0,08764396 0,11264497 ! G1 phase GO:0051318 40 19 0,000 0,08764396 0,11258482 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,08764396 0,11252475 ! cell-cell junction organization GO:0045216 35 19 0,000 0,08764396 0,11246473 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,08764396 0,11240478 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,08764396 0,1123449 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,08764396 0,11228508 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,08764396 0,11222532 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,08764396 0,11216562 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,08764396 0,11210599 ! cilium assembly GO:0042384 37 19 0,000 0,08764396 0,11204643 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,09203933 0,11760309 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,09203933 0,11754067 ! positive regulation of ossification GO:0045778 47 20 0,000 0,09203933 0,11747831 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,09203933 0,11741602 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,09203933 0,1173538 ! cAMP metabolic process GO:0046058 36 20 0,000 0,09203933 0,11729164 ! response to vitamin GO:0033273 31 20 0,000 0,09203933 0,11722955 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,09203933 0,11716752 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 0,09203933 0,11710556 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,09203933 0,11704367 ! retinoid metabolic process GO:0001523 32 20 0,000 0,09203933 0,11698184 GO:0016101|diterpenoid metabolic process, ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,09203933 0,11692007 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,09203933 0,11685837 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,09203933 0,11679674 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 0,000 0,09203933 0,11673517 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,09203933 0,11667367 ! body fluid secretion GO:0007589 31 20 0,000 0,09203933 0,11661223 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,09203933 0,11655085 ! stem cell differentiation GO:0048863 53 20 0,000 0,09203933 0,11648954 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,09203933 0,1164283 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,09203933 0,11636711 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,09203933 0,116306 ! sensory perception of pain GO:0019233 30 20 0,000 0,09203933 0,11624494 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,09203933 0,11618395 ! diencephalon development GO:0021536 34 20 0,000 0,09203933 0,11612303 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,09203933 0,11606217 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,09203933 0,11600137 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,09203933 0,11594064 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,09203933 0,11587997 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,09203933 0,11581936 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,09203933 0,11575882 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,09203933 0,11569834 ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,09203933 0,11563792 ! actin filament-based movement GO:0030048 43 20 0,000 0,09203933 0,11557757 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,09203933 0,11551728 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,09203933 0,11545705 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,09203933 0,11539688 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,09203933 0,11533678 ! regulation of cell killing GO:0031341 42 21 0,000 0,09641366 0,12075547 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,09641366 0,12069264 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,09641366 0,12062988 ! glycerol metabolic process GO:0006071 34 21 0,000 0,09641366 0,12056718 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,09641366 0,12050455 ! axis specification GO:0009798 38 21 0,000 0,09641366 0,12044198 ! smooth muscle contraction GO:0006939 46 21 0,000 0,09641366 0,12037948 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,09641366 0,12031704 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,09641366 0,12025467 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,09641366 0,12019236 ! cytolysis GO:0019835 24 21 0,000 0,09641366 0,12013012 ! vasodilation GO:0042311 39 21 0,000 0,09641366 0,12006794 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,09641366 0,12000583 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,09641366 0,11994378 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,09641366 0,11988179 ! collagen fibril organization GO:0030199 59 21 0,000 0,09641366 0,11981987 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,09641366 0,11975801 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,09641366 0,11969621 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,09641366 0,11963448 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,09641366 0,11957282 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,09641366 0,11951121 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,09641366 0,11944967 ! sperm-egg recognition GO:0035036 21 21 0,000 0,09641366 0,11938819 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,10076706 0,12471479 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,10076706 0,12465067 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,10076706 0,12458661 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,10076706 0,12452262 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,10076706 0,1244587 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,10076706 0,12439484 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,10076706 0,12433105 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,10076706 0,12426732 ! keratinization GO:0031424 28 22 0,000 0,10076706 0,12420366 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,10076706 0,12414007 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,10076706 0,12407654 ! sensory perception of taste GO:0050909 28 22 0,000 0,10076706 0,12401307 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,10076706 0,12394967 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,10076706 0,12388633 ! vacuolar transport GO:0007034 36 22 0,000 0,10076706 0,12382306 ! lysosome organization GO:0007040 41 22 0,000 0,10076706 0,12375985 ! central nervous system neuron development GO:0021954 46 22 0,000 0,10076706 0,12369671 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,10076706 0,12363363 ! fucose metabolic process GO:0006004 39 22 0,000 0,10076706 0,12357062 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,10076706 0,12350767 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,10076706 0,12344478 GO:0060415|muscle tissue morphogenesis, ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,10076706 0,12338196 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,10076706 0,1233192 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,10076706 0,12325651 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,10076706 0,12319388 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,10076706 0,12313131 ! protein stabilization GO:0050821 39 22 0,000 0,10076706 0,12306881 ! positive regulation of DNA replication GO:0045740 43 23 0,000 0,10509963 0,12829514 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,10509963 0,12823008 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,10509963 0,12816509 ! gluconeogenesis GO:0006094 33 23 0,000 0,10509963 0,12810016 ! viral genome replication GO:0019079 41 23 0,000 0,10509963 0,1280353 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,10509963 0,12797051 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,10509963 0,12790578 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,10509963 0,12784111 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,10509963 0,12777651 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,10509963 0,12771198 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,10509963 0,12764751 ! visual behavior GO:0007632 42 23 0,000 0,10509963 0,12758311 ! regulation of DNA recombination GO:0000018 48 23 0,000 0,10509963 0,12751877 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,10509963 0,1274545 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! peroxisome organization GO:0007031 37 23 0,000 0,10509963 0,12739029 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,10509963 0,12732614 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,10509963 0,12726206 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,10509963 0,12719805 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,10509963 0,1271341 GO:0051693|actin filament capping, ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,10509963 0,12707021 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,10509963 0,12700639 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,10509963 0,12694263 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,10509963 0,12687894 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,10509963 0,12681531 ! fatty acid transport GO:0015908 44 23 0,000 0,10509963 0,12675174 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,10509963 0,12668824 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,10509963 0,1266248 ! cell-cell recognition GO:0009988 25 23 0,000 0,10509963 0,12656142 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,10509963 0,12649811 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,10509963 0,12643486 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,10509963 0,12637167 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,10509963 0,12630855 GO:0006099|tricarboxylic acid cycle, ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,10941148 0,13142487 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,10941148 0,13135929 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,10941148 0,13129377 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,10941148 0,13122832 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,10941148 0,13116293 ! vesicle docking GO:0048278 47 24 0,000 0,10941148 0,13109761 ! spinal cord development GO:0021510 47 24 0,000 0,10941148 0,13103236 ! vacuole organization GO:0007033 43 24 0,000 0,10941148 0,13096717 ! digestive system process GO:0022600 39 24 0,000 0,10941148 0,13090204 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,10941148 0,13083698 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,10941148 0,13077199 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,10941148 0,13070706 ! membrane depolarization GO:0051899 39 24 0,000 0,10941148 0,13064219 ! pallium development GO:0021543 49 24 0,000 0,10941148 0,13057739 ! pentose metabolic process GO:0019321 35 24 0,000 0,10941148 0,13051265 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,10941148 0,13044797 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,10941148 0,13038336 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,10941148 0,13031882 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,10941148 0,13025433 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,10941148 0,13018992 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,10941148 0,13012556 ! regulation of amine transport GO:0051952 40 24 0,000 0,10941148 0,13006127 ! protein tetramerization GO:0051262 52 24 0,000 0,10941148 0,12999704 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,11370268 0,13502895 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,11370268 0,13496234 ! phototransduction GO:0007602 33 25 0,000 0,11370268 0,13489579 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,11370268 0,1348293 GO:0006479|protein amino acid methylation, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 0,000 0,11370268 0,13476289 ! sperm motility GO:0030317 31 25 0,000 0,11370268 0,13469653 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,11370268 0,13463025 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,11370268 0,13456402 ! receptor metabolic process GO:0043112 46 25 0,000 0,11370268 0,13449787 ! chromosome condensation GO:0030261 45 25 0,000 0,11370268 0,13443177 ! response to starvation GO:0042594 42 25 0,000 0,11370268 0,13436575 ! osteoblast differentiation GO:0001649 60 25 0,000 0,11370268 0,13429978 ! neural crest cell development GO:0014032 54 25 0,000 0,11370268 0,13423389 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,11370268 0,13416805 ! negative regulation of cell development GO:0010721 73 25 0,000 0,11370268 0,13410228 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,11370268 0,13403658 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,11370268 0,13397094 ! interaction with host GO:0051701 62 25 0,000 0,11370268 0,13390536 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,11370268 0,13383985 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,11370268 0,1337744 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,11370268 0,13370902 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! immunoglobulin production GO:0002377 55 25 0,000 0,11370268 0,1336437 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,11370268 0,13357845 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,11370268 0,13351325 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,11370268 0,13344813 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,11370268 0,13338306 ! telomere organization GO:0032200 43 25 0,000 0,11370268 0,13331806 GO:0000723|telomere maintenance, ! liver development GO:0001889 53 25 0,000 0,11370268 0,13325312 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,11797336 0,1381908 ! embryonic pattern specification GO:0009880 44 26 0,000 0,11797336 0,13812355 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,11797336 0,13805637 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,11797336 0,13798926 ! initiation of viral infection GO:0019059 57 26 0,000 0,11797336 0,13792221 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,11797336 0,13785522 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,11797336 0,1377883 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,11797336 0,13772145 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,11797336 0,13765466 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,11797336 0,13758793 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,11797336 0,13752127 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,11797336 0,13745467 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,11797336 0,13738814 GO:0051297|centrosome organization, ! insulin receptor signaling pathway GO:0008286 64 26 0,000 0,11797336 0,13732167 ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,11797336 0,13725527 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,11797336 0,13718893 ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,11797336 0,13712266 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,11797336 0,13705645 ! blastocyst development GO:0001824 49 26 0,000 0,11797336 0,1369903 ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,11797336 0,13692422 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,11797336 0,1368582 ! neuron fate commitment GO:0048663 48 27 0,000 0,12222359 0,14172047 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,12222359 0,1416522 ! iron ion transport GO:0006826 59 27 0,000 0,12222359 0,141584 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,12222359 0,14151586 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,12222359 0,1414478 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,12222359 0,14137979 ! fat cell differentiation GO:0045444 50 27 0,000 0,12222359 0,14131185 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,12222359 0,14124398 ! autophagy GO:0006914 41 27 0,000 0,12222359 0,14117617 ! base-excision repair GO:0006284 41 27 0,000 0,12222359 0,14110843 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,12222359 0,14104075 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,12222359 0,14097314 ! glutathione metabolic process GO:0006749 39 27 0,000 0,12222359 0,14090559 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,12222359 0,14083811 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,12222359 0,14077069 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,12222359 0,14070333 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,12645349 0,14550316 ! circadian rhythm GO:0007623 50 28 0,000 0,12645349 0,1454336 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,12645349 0,14536412 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,12645349 0,1452947 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,12645349 0,14522535 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,12645349 0,14515606 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,12645349 0,14508684 ! synaptogenesis GO:0007416 42 28 0,000 0,12645349 0,14501768 ! lipid oxidation GO:0034440 43 28 0,000 0,12645349 0,14494859 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,12645349 0,14487957 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,12645349 0,14481061 ! translational initiation GO:0006413 65 29 0,000 0,13066314 0,14956019 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,13066314 0,14948907 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,13066314 0,14941802 ! regulation of pH GO:0006885 43 29 0,000 0,13066314 0,14934704 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,13066314 0,14927613 ! catechol metabolic process GO:0009712 54 29 0,000 0,13066314 0,14920528 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,13066314 0,1491345 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,13066314 0,14906378 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,13066314 0,14899314 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,13066314 0,14892256 GO:0002764|immune response-regulating signal transduction, ! cell fate determination GO:0001709 60 29 0,000 0,13066314 0,14885205 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,13066314 0,1487816 ! detection of light stimulus GO:0009583 38 29 0,000 0,13066314 0,14871122 ! regulation of coagulation GO:0050818 46 29 0,000 0,13066314 0,14864091 ! phenol metabolic process GO:0018958 55 30 0,000 0,13485265 0,15333434 ! zinc ion transport GO:0006829 45 30 0,000 0,13485265 0,15326191 ! membrane docking GO:0022406 61 30 0,000 0,13485265 0,15318955 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,13485265 0,15311726 ! regulation of innate immune response GO:0045088 51 30 0,000 0,13485265 0,15304503 ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,13485265 0,15297288 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,13485265 0,15290079 ! phospholipid transport GO:0015914 51 30 0,000 0,13485265 0,15282877 ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,13485265 0,15275681 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,13485265 0,15268493 ! eye morphogenesis GO:0048592 60 30 0,000 0,13485265 0,15261311 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,1390221 0,15725772 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,1390221 0,15718382 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,1390221 0,15711 GO:0009799|determination of symmetry, ! inner ear morphogenesis GO:0042472 47 31 0,000 0,1390221 0,15703623 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,1390221 0,15696254 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,1390221 0,15688892 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,1390221 0,15681537 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,1390221 0,15674188 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,1390221 0,15666847 ! mesoderm formation GO:0001707 69 31 0,000 0,1390221 0,15659512 ! natural killer cell activation GO:0030101 45 31 0,000 0,1390221 0,15652184 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,1390221 0,15644863 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,1390221 0,15637549 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,1390221 0,15630242 ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,1390221 0,15622942 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,1431716 0,1608174 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,1431716 0,16074236 ! cholesterol transport GO:0030301 56 32 0,000 0,1431716 0,16066738 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,1431716 0,16059248 ! spliceosome assembly GO:0000245 67 32 0,000 0,1431716 0,16051765 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,1431716 0,16044288 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,1431716 0,16036819 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,1431716 0,16029357 ! regulation of protein import into nucleus GO:0042306 63 32 0,000 0,1431716 0,16021901 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,1431716 0,16014452 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,1431716 0,16007011 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,1431716 0,15999576 ! BMP signaling pathway GO:0030509 64 32 0,000 0,1431716 0,15992148 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,1431716 0,15984727 ! positive regulation of catabolic process GO:0009896 64 32 0,000 0,1431716 0,15977313 ! gene silencing GO:0016458 65 32 0,000 0,1431716 0,15969906 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,14730124 0,16422928 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,14730124 0,16415321 ! protein targeting to membrane GO:0006612 68 33 0,000 0,14730124 0,16407721 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,14730124 0,16400129 ! ceramide metabolic process GO:0006672 64 33 0,000 0,14730124 0,16392543 ! formation of primary germ layer GO:0001704 72 33 0,000 0,14730124 0,16384964 ! cell fate specification GO:0001708 52 33 0,000 0,14730124 0,16377393 ! sterol transport GO:0015918 57 33 0,000 0,14730124 0,16369828 ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,14730124 0,1636227 ! adult locomotory behavior GO:0008344 59 33 0,000 0,14730124 0,1635472 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,14730124 0,16347176 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,14730124 0,16339639 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,15141111 0,16787794 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,15141111 0,16780061 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,15141111 0,16772335 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,15141111 0,16764617 ! mismatch repair GO:0006298 46 34 0,000 0,15141111 0,16756905 ! spermatid development GO:0007286 63 34 0,000 0,15141111 0,16749201 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,15141111 0,16741504 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,15141111 0,16733814 ! placenta development GO:0001890 53 34 0,000 0,15141111 0,16726131 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 0,000 0,15141111 0,16718455 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,1555013 0,17162208 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,1555013 0,17154339 ! odontogenesis GO:0042476 66 35 0,000 0,1555013 0,17146477 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,1555013 0,17138623 ! telencephalon development GO:0021537 68 35 0,000 0,1555013 0,17130776 ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 0,1555013 0,17122935 ! cytokine production GO:0001816 59 35 0,000 0,1555013 0,17115102 ! vesicle localization GO:0051648 64 35 0,000 0,1555013 0,17107277 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,15957192 0,17547077 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! sphingoid metabolic process GO:0046519 70 36 0,000 0,15957192 0,17539061 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,15957192 0,17531052 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,15957192 0,17523051 ! regulation of proteolysis GO:0030162 72 36 0,000 0,15957192 0,17515057 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,15957192 0,1750707 ! aerobic respiration GO:0009060 55 36 0,000 0,15957192 0,1749909 ! embryonic organ development GO:0048568 57 36 0,000 0,15957192 0,17491118 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,15957192 0,17483153 ! RNA export from nucleus GO:0006405 56 37 0,000 0,16362305 0,17918847 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,16362305 0,17910694 ! organic anion transport GO:0015711 68 37 0,000 0,16362305 0,1790255 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,16362305 0,17894412 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,16362305 0,17886282 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,16362305 0,17878159 GO:0015986|ATP synthesis coupled proton transport, ! spermatid differentiation GO:0048515 66 37 0,000 0,16362305 0,17870044 ! cellular response to insulin stimulus GO:0032869 82 37 0,000 0,16362305 0,17861936 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,16765479 0,18293761 GO:0006956|complement activation, ! positive regulation of DNA metabolic process GO:0051054 72 38 0,000 0,16765479 0,18285468 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,16765479 0,18277183 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,16765479 0,18268905 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,16765479 0,18260635 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,16765479 0,18252372 ! carbohydrate homeostasis GO:0033500 53 38 0,000 0,16765479 0,18244117 GO:0042593|glucose homeostasis, ! lipid homeostasis GO:0055088 67 38 0,000 0,16765479 0,18235869 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,16765479 0,18227629 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,16765479 0,18219396 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,16765479 0,1821117 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,16765479 0,18202952 ! mRNA catabolic process GO:0006402 71 39 0,000 0,17166723 0,18630191 ! learning GO:0007612 77 39 0,000 0,17166723 0,18621792 ! ion transmembrane transport GO:0034220 66 39 0,000 0,17166723 0,186134 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,17166723 0,18605016 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,17166723 0,18596639 ! RNA modification GO:0009451 57 39 0,000 0,17166723 0,18588269 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,17166723 0,18579908 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,17566045 0,19003554 ! feeding behavior GO:0007631 59 40 0,000 0,17566045 0,18995013 ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,17566045 0,1898648 ! maintenance of protein location GO:0045185 91 40 0,000 0,17566045 0,18977954 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,17963456 0,19398597 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,17963456 0,19389895 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,17963456 0,193812 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,17963456 0,19372512 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,17963456 0,19363833 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,17963456 0,19355161 ! polyol metabolic process GO:0019751 66 41 0,000 0,17963456 0,19346497 ! regulation of tube size GO:0035150 71 42 0,000 0,18358964 0,19763609 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,18358964 0,19754771 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,18358964 0,1974594 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,18358964 0,19737117 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,18358964 0,19728302 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,18358964 0,19719494 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,18752578 0,2013329 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,18752578 0,2012431 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,18752578 0,20115338 ! glucose transport GO:0015758 65 43 0,000 0,18752578 0,20106374 ! striated muscle contraction GO:0006941 77 43 0,000 0,18752578 0,20097418 ! phagocytosis GO:0006909 90 43 0,000 0,18752578 0,2008847 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,18752578 0,2007953 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,19144308 0,2048986 ! hexose transport GO:0008645 67 44 0,000 0,19144308 0,20480749 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,19144308 0,20471646 ! double-strand break repair GO:0006302 81 44 0,000 0,19144308 0,20462552 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,19144308 0,20453466 ! maintenance of location in cell GO:0051651 97 44 0,000 0,19144308 0,20444387 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,19534162 0,20851461 ! glycolysis GO:0006096 65 45 0,000 0,19534162 0,20842214 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,19534162 0,20832976 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,19534162 0,20823745 ! icosanoid metabolic process GO:0006690 80 45 0,000 0,19534162 0,20814523 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,19534162 0,20805309 ! cell growth GO:0016049 84 45 0,000 0,19534162 0,20796103 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,19922149 0,21199774 ! regulation of gene-specific transcription GO:0032583 96 46 0,000 0,19922149 0,21190402 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,19922149 0,21181038 ! response to insulin stimulus GO:0032868 95 46 0,000 0,19922149 0,21171683 ! endosome transport GO:0016197 108 47 0,000 0,20308278 0,21572502 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,20308278 0,21562982 ! JNK cascade GO:0007254 91 47 0,000 0,20308278 0,2155347 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,20308278 0,21543967 ! Notch signaling pathway GO:0007219 96 48 0,000 0,20692558 0,21941954 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,20692558 0,21932288 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,20692558 0,21922631 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,20692558 0,21912982 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,21074998 0,22308158 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,21074998 0,22298348 ! regulation of ion transport GO:0043269 77 49 0,000 0,21074998 0,22288547 ! peptide metabolic process GO:0006518 76 49 0,000 0,21074998 0,22278754 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,21074998 0,2226897 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,21074998 0,22259194 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,21074998 0,22249427 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,21074998 0,22239668 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,21455606 0,22631384 ! neuromuscular process GO:0050905 99 50 0,000 0,21455606 0,22621467 ! inner ear development GO:0048839 79 50 0,000 0,21455606 0,22611558 ! viral infectious cycle GO:0019058 99 51 0,000 0,21834391 0,23000676 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,21834391 0,2299061 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,21834391 0,22980553 ! excretion GO:0007588 83 51 0,000 0,21834391 0,22970505 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,21834391 0,22960465 ! chromatin remodeling GO:0006338 109 51 0,000 0,21834391 0,22950435 ! membrane fusion GO:0006944 110 52 0,000 0,22211362 0,23336479 ! RNA catabolic process GO:0006401 93 53 0,000 0,22586528 0,2372029 ! regulation of translational initiation GO:0006446 82 53 0,000 0,22586528 0,23709941 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,22586528 0,23699601 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,22586528 0,2368927 ! cell maturation GO:0048469 100 53 0,000 0,22586528 0,23678948 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,22586528 0,23668635 ! cell recognition GO:0008037 85 54 0,000 0,22959896 0,24049417 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,22959896 0,24038951 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,22959896 0,24028495 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,22959896 0,24018048 ! chloride transport GO:0006821 90 55 0,000 0,23331476 0,24396146 ! glucose catabolic process GO:0006007 82 55 0,000 0,23331476 0,24385548 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,23331476 0,2437496 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,23331476 0,2436438 ! gastrulation GO:0007369 112 55 0,000 0,23331476 0,2435381 ! heart morphogenesis GO:0003007 97 55 0,000 0,23331476 0,24343249 ! RNA elongation GO:0006354 79 55 0,000 0,23331476 0,24332697 ! nuclear export GO:0051168 97 55 0,000 0,23331476 0,24322154 ! sensory perception of smell GO:0007608 80 56 0,000 0,23701277 0,24696956 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,23701277 0,24686265 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,23701277 0,24675583 ! regulation of DNA replication GO:0006275 101 56 0,000 0,23701277 0,2466491 ! proton transport GO:0015992 94 56 0,000 0,23701277 0,24654246 ! lipid modification GO:0030258 97 57 0,000 0,24069306 0,25026253 ! maintenance of location GO:0051235 118 57 0,000 0,24069306 0,25015442 ! hydrogen transport GO:0006818 97 58 0,000 0,24435571 0,2538514 ! regulation of endocytosis GO:0030100 91 58 0,000 0,24435571 0,25374184 ! adult behavior GO:0030534 99 58 0,000 0,24435571 0,25363238 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,24800083 0,25730487 GO:0032313|regulation of Rab GTPase activity, ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,24800083 0,25719396 ! DNA damage response, signal transduction GO:0042770 128 60 0,000 0,25162847 0,26084365 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,25162847 0,26073131 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,25523874 0,26435834 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,25523874 0,26424459 ! mesoderm development GO:0007498 119 61 0,000 0,25523874 0,26413093 ! tRNA processing GO:0008033 89 61 0,000 0,25523874 0,26401738 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,25523874 0,26390392 ! viral reproductive process GO:0022415 126 62 0,000 0,25883172 0,26750391 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,25883172 0,26738906 ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,26240747 0,27096669 ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,26240747 0,27085044 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,26240747 0,2707343 ! cell redox homeostasis GO:0045454 102 64 0,000 0,2659661 0,27428823 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,2659661 0,27417071 ! single fertilization GO:0007338 75 64 0,000 0,2659661 0,27405329 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,26950767 0,27758367 ! myeloid cell differentiation GO:0030099 111 65 0,000 0,26950767 0,2774649 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,27303228 0,28097334 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,27303228 0,28085321 ! extracellular matrix organization GO:0030198 133 66 0,000 0,27303228 0,28073319 ! developmental maturation GO:0021700 116 66 0,000 0,27303228 0,28061327 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,27653999 0,28409702 ! activation of MAPK activity GO:0000187 115 67 0,000 0,27653999 0,28397577 ! hexose catabolic process GO:0019320 104 67 0,000 0,27653999 0,28385462 ! activation of immune response GO:0002253 105 67 0,000 0,27653999 0,28373357 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,2800309 0,28719281 ! viral reproduction GO:0016032 134 68 0,000 0,2800309 0,28707045 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,2800309 0,28694818 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,28350507 0,29038451 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,28350507 0,29026094 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,28350507 0,29013748 ! antigen processing and presentation GO:0019882 104 69 0,000 0,28350507 0,29001412 ! amine catabolic process GO:0009310 117 71 0,000 0,29040356 0,29694473 ! phosphoinositide metabolic process GO:0030384 128 72 0,000 0,29382802 0,3003187 ! carbohydrate transport GO:0008643 110 72 0,000 0,29382802 0,30019118 ! regulation of blood pressure GO:0008217 125 73 0,000 0,29723607 0,30354414 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,29723607 0,30341536 ! fertilization GO:0009566 90 73 0,000 0,29723607 0,30328668 ! transition metal ion transport GO:0000041 126 74 0,000 0,30062779 0,30661741 ! exocytosis GO:0006887 133 74 0,000 0,30062779 0,30648749 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,30400325 0,30979747 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,30736253 0,31308817 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,30736253 0,31295567 ! regulation of catabolic process GO:0009894 161 76 0,000 0,30736253 0,31282329 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,31070571 0,31609215 ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,31403287 0,31934196 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,31734407 0,3225728 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,31734407 0,32243658 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,31734407 0,32230048 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,31734407 0,32216448 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,3206394 0,32537258 ! inorganic anion transport GO:0015698 138 80 0,000 0,3206394 0,32523541 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,32718274 0,33173269 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,32718274 0,33159295 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,32718274 0,33145333 ! cellular response to hormone stimulus GO:0032870 167 82 0,000 0,32718274 0,33131383 ! regulation of lyase activity GO:0051339 160 83 0,000 0,3304309 0,33446224 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,33366349 0,33759224 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,33366349 0,33745033 ! response to unfolded protein GO:0006986 131 85 0,000 0,33688057 0,34056078 ! nucleosome assembly GO:0006334 122 85 0,000 0,33688057 0,34041775 ! amine biosynthetic process GO:0009309 138 86 0,000 0,34008224 0,34350876 ! chromatin assembly GO:0031497 124 86 0,000 0,34008224 0,34336461 ! alcohol catabolic process GO:0046164 130 86 0,000 0,34008224 0,34322058 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,34326855 0,34629104 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,34326855 0,3461459 ! regulation of neurological system process GO:0031644 148 88 0,000 0,34643958 0,34919716 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,34643958 0,34905093 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,35273609 0,35524614 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,35273609 0,35509751 ! sterol metabolic process GO:0016125 152 91 0,000 0,35586172 0,35809423 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,35586172 0,35794452 ! nucleosome organization GO:0034728 138 92 0,000 0,35897236 0,36092248 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,35897236 0,36077172 ! vitamin metabolic process GO:0006766 139 92 0,000 0,35897236 0,36062109 ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,36206808 0,36357922 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,36206808 0,36342754 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,36514895 0,36636713 ! forebrain development GO:0030900 188 95 0,000 0,36821505 0,36928946 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,36821505 0,36913559 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,37126644 0,37203959 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! positive regulation of immune response GO:0050778 156 96 0,000 0,37126644 0,3718847 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,37430319 0,37477049 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,37732538 0,37763929 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,37732538 0,37748227 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,38033307 0,38033307