pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6735-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! phospholipid dephosphorylation GO:0046839 12 5 3,000 2,188E-10 5,263E-07 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 3,000 6,55E-10 7,879E-07 ! negative regulation of focal adhesion formation GO:0051895 20 7 3,000 1,525E-09 1,223E-06 ! regulation of focal adhesion formation GO:0051893 22 8 3,000 3,044E-09 1,831E-06 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 3,000 9,097E-09 4,377E-06 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 3,000 1,427E-08 5,721E-06 GO:0010812|negative regulation of cell-substrate adhesion, ! endothelial cell migration GO:0043542 28 17 3,000 1,017E-07 3,494E-05 ! inositol metabolic process GO:0006020 28 17 3,000 1,017E-07 3,058E-05 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 3,000 1,017E-07 2,718E-05 ! cardiac muscle tissue development GO:0048738 31 17 3,000 1,017E-07 2,446E-05 ! negative regulation of cell migration GO:0030336 115 46 4,000 1,376E-07 3,01E-05 ! negative regulation of cell motion GO:0051271 134 55 4,000 3,429E-07 6,874E-05 ! regulation of cell-matrix adhesion GO:0001952 78 23 3,000 3,738E-07 6,918E-05 GO:0010810|regulation of cell-substrate adhesion, ! acetyl-CoA catabolic process GO:0046356 36 23 3,000 3,738E-07 6,424E-05 GO:0006099|tricarboxylic acid cycle, ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 4,000 4,11E-07 6,592E-05 ! lipid modification GO:0030258 97 57 4,000 4,11E-07 6,18E-05 ! coenzyme catabolic process GO:0009109 39 25 3,000 5,318E-07 7,527E-05 ! acetyl-CoA metabolic process GO:0006084 39 26 3,000 6,273E-07 8,385E-05 ! negative regulation of protein kinase cascade GO:0010741 68 30 3,000 1,141E-06 1,445E-04 ! cofactor catabolic process GO:0051187 51 30 3,000 1,141E-06 1,372E-04 ! phosphoinositide metabolic process GO:0030384 128 72 4,000 1,332E-06 1,526E-04 ! negative regulation of cell adhesion GO:0007162 81 35 3,000 2,158E-06 2,36E-04 ! aerobic respiration GO:0009060 55 36 3,000 2,423E-06 2,534E-04 ! regulation of protein stability GO:0031647 73 37 3,000 2,711E-06 2,718E-04 ! cellular respiration GO:0045333 135 88 4,000 3,609E-06 3,473E-04 ! polyol metabolic process GO:0019751 66 41 3,000 4,124E-06 3,816E-04 ! glutathione metabolic process GO:0006749 39 27 2,000 4,855E-05 4,327E-03 ! Notch receptor processing GO:0007220 8 5 1,000 6,759E-05 5,808E-03 ! microvillus organization GO:0032528 7 5 1,000 6,759E-05 5,608E-03 GO:0030033|microvillus assembly, ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 6,759E-05 5,421E-03 ! regulation of cell adhesion GO:0030155 212 89 3,000 9,038E-05 7,015E-03 ! erythrocyte maturation GO:0043249 7 6 1,000 1,012E-04 7,61E-03 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 1,000 1,012E-04 7,379E-03 ! N-terminal protein amino acid acetylation GO:0006474 13 7 1,000 1,415E-04 0,01001026 ! amyloid precursor protein catabolic process GO:0042987 11 7 1,000 1,415E-04 9,724E-03 ! vesicle fusion GO:0006906 17 7 1,000 1,415E-04 9,454E-03 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 1,000 1,415E-04 9,199E-03 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 1,000 1,415E-04 8,957E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 1,883E-04 0,01161605 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 1,000 1,883E-04 0,01132564 ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 1,000 1,883E-04 0,01104941 ! pentose-phosphate shunt GO:0006098 16 9 1,000 2,417E-04 0,01384452 GO:0006740|NADPH regeneration, ! amyloid precursor protein metabolic process GO:0042982 14 9 1,000 2,417E-04 0,01352256 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 1,000 2,417E-04 0,01321523 ! retrograde transport, endosome to Golgi GO:0042147 24 9 1,000 2,417E-04 0,01292156 ! erythrocyte development GO:0048821 15 9 1,000 2,417E-04 0,01264065 ! peptide metabolic process GO:0006518 76 49 2,000 2,934E-04 0,01501892 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 1,000 3,016E-04 0,01511667 ! localization within membrane GO:0051668 20 10 1,000 3,016E-04 0,01480817 ! negative regulation of blood pressure GO:0045776 26 10 1,000 3,016E-04 0,014512 ! regulation of smooth muscle cell migration GO:0014910 27 10 1,000 3,016E-04 0,01422745 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 1,000 3,68E-04 0,01702568 ! peptide or protein amino-terminal blocking GO:0018409 21 11 1,000 3,68E-04 0,01670444 ! vasoconstriction GO:0042310 18 11 1,000 3,68E-04 0,0163951 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 1,000 3,68E-04 0,01609701 ! cell maturation GO:0048469 100 53 2,000 3,702E-04 0,01590697 ! glucose catabolic process GO:0006007 82 55 2,000 4,131E-04 0,01743598 ! positive regulation of blood pressure GO:0045777 17 12 1,000 4,408E-04 0,01828611 ! membrane protein proteolysis GO:0033619 25 12 1,000 4,408E-04 0,01797618 GO:0006509|membrane protein ectodomain proteolysis, ! histone acetylation GO:0016573 26 12 1,000 4,408E-04 0,01767657 ! peptidyl-lysine modification GO:0018205 21 12 1,000 4,408E-04 0,01738679 ! organelle fusion GO:0048284 32 13 1,000 5,201E-04 0,02018221 ! regulation of monooxygenase activity GO:0032768 33 13 1,000 5,201E-04 0,01986186 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 1,000 5,201E-04 0,01955152 ! N-terminal protein amino acid modification GO:0031365 27 14 1,000 6,057E-04 0,02242098 ! reproductive cellular process GO:0048610 20 14 1,000 6,057E-04 0,02208127 ! NADP metabolic process GO:0006739 24 14 1,000 6,057E-04 0,0217517 ! cell redox homeostasis GO:0045454 102 64 2,000 6,45E-04 0,02282071 ! glycoprotein catabolic process GO:0006516 26 15 1,000 6,977E-04 0,02432918 ! positive regulation of axonogenesis GO:0050772 28 15 1,000 6,977E-04 0,02398162 ! extracellular matrix organization GO:0030198 133 66 2,000 7,057E-04 0,02391495 ! developmental maturation GO:0021700 116 66 2,000 7,057E-04 0,02358279 ! hexose catabolic process GO:0019320 104 67 2,000 7,374E-04 0,02430425 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 1,000 9,006E-04 0,02928306 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 1,012E-03 0,03244895 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 1,000 1,012E-03 0,03202199 GO:0050886|endocrine process, ! monosaccharide catabolic process GO:0046365 115 76 2,000 1,064E-03 0,03324566 ! lipid phosphorylation GO:0046834 35 19 1,000 1,129E-03 0,03481234 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 1,000 1,129E-03 0,03437168 ! protein amino acid acetylation GO:0006473 39 20 1,000 1,252E-03 0,03764929 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 1,000 1,252E-03 0,03718449 ! D-ribose metabolic process GO:0006014 29 20 1,000 1,252E-03 0,03673102 ! negative regulation of translation GO:0017148 29 20 1,000 1,252E-03 0,03628848 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 1,000 1,381E-03 0,03956351 ! vasodilation GO:0042311 39 21 1,000 1,381E-03 0,03909806 ! cholesterol biosynthetic process GO:0006695 37 21 1,000 1,381E-03 0,03864343 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 1,000 1,517E-03 0,04194781 ! vesicle docking during exocytosis GO:0006904 41 22 1,000 1,517E-03 0,04147113 ! renal system process GO:0003014 41 22 1,000 1,517E-03 0,04100516 ! alcohol catabolic process GO:0046164 130 86 2,000 1,52E-03 0,04063597 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 1,000 1,658E-03 0,04384879 ! vesicle docking GO:0048278 47 24 1,000 1,806E-03 0,04723476 ! pentose metabolic process GO:0019321 35 24 1,000 1,806E-03 0,04672686 ! regulation of oxidoreductase activity GO:0051341 46 24 1,000 1,806E-03 0,04622977 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 1,000 1,96E-03 0,0496364 ! somitogenesis GO:0001756 43 25 1,000 1,96E-03 0,04911936 ! insulin receptor signaling pathway GO:0008286 64 26 1,000 2,12E-03 0,05257468 ! cellular response to oxidative stress GO:0034599 39 26 1,000 2,12E-03 0,0520382 ! water-soluble vitamin biosynthetic process GO:0042364 35 26 1,000 2,12E-03 0,05151256 ! Golgi vesicle transport GO:0048193 207 99 2,000 2,274E-03 0,05470045 ! positive regulation of cell projection organization GO:0031346 58 27 1,000 2,285E-03 0,05443938 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 1,000 2,285E-03 0,05390566 ! protein amino acid acylation GO:0043543 55 27 1,000 2,285E-03 0,05338231 ! negative regulation of protein modification process GO:0031400 60 28 1,000 2,457E-03 0,05683927 ! vitamin biosynthetic process GO:0009110 39 28 1,000 2,457E-03 0,05629794 ! regulation of systemic arterial blood pressure GO:0003073 54 28 1,000 2,457E-03 0,05576683 ! sterol biosynthetic process GO:0016126 52 29 1,000 2,634E-03 0,05923727 ! membrane docking GO:0022406 61 30 1,000 2,818E-03 0,06277419 ! nicotinamide metabolic process GO:0006769 52 30 1,000 2,818E-03 0,06219828 GO:0046496|nicotinamide nucleotide metabolic process, ! alkaloid metabolic process GO:0009820 53 31 1,000 3,007E-03 0,06577168 ! erythrocyte differentiation GO:0030218 55 31 1,000 3,007E-03 0,06517914 ! regulation of axonogenesis GO:0050770 75 32 1,000 3,202E-03 0,06878686 ! positive regulation of neurogenesis GO:0050769 67 33 1,000 3,403E-03 0,07245371 ! pyridine nucleotide metabolic process GO:0019362 55 33 1,000 3,403E-03 0,07181815 ! spermatid development GO:0007286 63 34 1,000 3,609E-03 0,07551507 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 1,000 3,822E-03 0,07926677 ! calcium-mediated signaling GO:0019722 62 35 1,000 3,822E-03 0,07858927 ! cytokine production GO:0001816 59 35 1,000 3,822E-03 0,07792326 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 1,000 4,04E-03 0,08167507 ! positive regulation of cell development GO:0010720 80 36 1,000 4,04E-03 0,08099444 ! androgen receptor signaling pathway GO:0030521 74 36 1,000 4,04E-03 0,08032507 ! monosaccharide biosynthetic process GO:0046364 52 36 1,000 4,04E-03 0,07966666 ! spermatid differentiation GO:0048515 66 37 1,000 4,263E-03 0,08339287 ! cellular response to insulin stimulus GO:0032869 82 37 1,000 4,263E-03 0,08272034 ! regulation of neuron projection development GO:0010975 91 38 1,000 4,492E-03 0,08647073 ! erythrocyte homeostasis GO:0034101 64 38 1,000 4,492E-03 0,08578445 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 1,000 4,492E-03 0,08510898 ! segmentation GO:0035282 67 39 1,000 4,727E-03 0,08885793 ! cellular amide metabolic process GO:0043603 67 41 1,000 5,214E-03 0,09723908 ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 5,465E-03 0,10114422 GO:0090047|positive regulation of transcription regulator activity, ! alcohol biosynthetic process GO:0046165 59 42 1,000 5,465E-03 0,10037213 ! regulation of tube size GO:0035150 71 42 1,000 5,465E-03 0,09961174 GO:0050880|regulation of blood vessel size, ! regulation of epithelial cell proliferation GO:0050678 111 43 1,000 5,722E-03 0,10350996 ! glycolysis GO:0006096 65 45 1,000 6,252E-03 0,11225516 ! ATP synthesis coupled electron transport GO:0042773 64 45 1,000 6,252E-03 0,11142364 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 1,000 6,252E-03 0,11060434 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 1,000 6,525E-03 0,11459373 ! response to insulin stimulus GO:0032868 95 46 1,000 6,525E-03 0,11376334 ! endosome transport GO:0016197 108 47 1,000 6,804E-03 0,11776528 ! positive regulation of DNA binding GO:0043388 73 47 1,000 6,804E-03 0,11692409 ! vascular process in circulatory system GO:0003018 80 47 1,000 6,804E-03 0,11609485 ! positive regulation of cell cycle GO:0045787 89 48 1,000 7,087E-03 0,12008605 ! Notch signaling pathway GO:0007219 96 48 1,000 7,087E-03 0,11924629 ! regulation of cell projection organization GO:0031344 121 50 1,000 7,671E-03 0,12816715 ! histone modification GO:0016570 91 50 1,000 7,671E-03 0,12728323 ! positive regulation of binding GO:0051099 78 51 1,000 7,97E-03 0,13134886 ! vesicle organization GO:0016050 107 51 1,000 7,97E-03 0,13045533 ! membrane fusion GO:0006944 110 52 1,000 8,275E-03 0,13452928 ! covalent chromatin modification GO:0016569 101 52 1,000 8,275E-03 0,1336264 ! respiratory electron transport chain GO:0022904 76 53 1,000 8,585E-03 0,13770798 ! response to UV GO:0009411 104 53 1,000 8,585E-03 0,13679601 ! activation of phospholipase C activity GO:0007202 103 54 1,000 8,9E-03 0,1408846 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of phospholipase activity GO:0010518 104 55 1,000 9,221E-03 0,14500031 ! gastrulation GO:0007369 112 55 1,000 9,221E-03 0,14405875 ! regulation of multicellular organism growth GO:0040014 85 55 1,000 9,221E-03 0,14312934 ! positive regulation of cell migration GO:0030335 126 57 1,000 9,877E-03 0,15232652 ! regulation of phospholipase activity GO:0010517 106 57 1,000 9,877E-03 0,15135629 ! positive regulation of lipase activity GO:0060193 108 58 1,000 0,01021201 0,15550697 ! protein amino acid autophosphorylation GO:0046777 141 60 1,000 0,01089798 0,16490903 ! response to peptide hormone stimulus GO:0043434 122 61 1,000 0,01124841 0,16914794 ! water-soluble vitamin metabolic process GO:0006767 95 62 1,000 0,01160377 0,17340783 ! steroid hormone receptor signaling pathway GO:0030518 129 63 1,000 0,01196402 0,17768791 ! positive regulation of cell motion GO:0051272 146 64 1,000 0,01232915 0,18198739 ! germ cell development GO:0007281 118 65 1,000 0,01269913 0,18630553 ! myeloid cell differentiation GO:0030099 111 65 1,000 0,01269913 0,18517641 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,01304775 0,1891138 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,01304775 0,18798138 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,01304775 0,18686244 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,01304775 0,18575675 ! neuron fate determination GO:0048664 7 5 0,000 0,01304775 0,18466406 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01304775 0,18358415 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,01304775 0,18251681 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,01304775 0,18146179 ! polyol transport GO:0015791 12 5 0,000 0,01304775 0,18041891 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,01304775 0,17938795 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,01304775 0,1783687 ! response to superoxide GO:0000303 10 5 0,000 0,01304775 0,17736096 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,01304775 0,17636455 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,01304775 0,17537928 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,01304775 0,17440495 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,01304775 0,17344138 ! female meiosis GO:0007143 7 5 0,000 0,01304775 0,17248841 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,01304775 0,17154585 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,01304775 0,17061354 ! cobalt ion transport GO:0006824 11 5 0,000 0,01304775 0,1696913 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,01304775 0,16877898 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,01304775 0,16787642 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,01304775 0,16698346 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,01304775 0,16609995 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,01304775 0,16522574 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,01304775 0,16436068 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,01304775 0,16350464 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,01304775 0,16265746 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,01304775 0,16181902 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01304775 0,16098918 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,01304775 0,16016781 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,01304775 0,15935477 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 0,01304775 0,15854995 ! negative chemotaxis GO:0050919 14 5 0,000 0,01304775 0,15775322 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,01304775 0,15696445 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,01304775 0,15618353 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,01304775 0,15541035 ! behavioral response to pain GO:0048266 9 5 0,000 0,01304775 0,15464478 ! clathrin coat assembly GO:0048268 14 5 0,000 0,01304775 0,15388672 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01304775 0,15313605 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,01304775 0,15239267 ! micturition GO:0060073 9 5 0,000 0,01304775 0,15165648 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,01304775 0,15092736 ! copulation GO:0007620 9 5 0,000 0,01304775 0,15020522 ! glial cell fate commitment GO:0021781 13 5 0,000 0,01304775 0,14948995 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,01304775 0,14878147 ! spermidine metabolic process GO:0008216 7 5 0,000 0,01304775 0,14807967 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,01304775 0,14738446 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,01304775 0,14669575 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,01304775 0,14601344 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,01304775 0,14533746 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,01304775 0,1446677 ! grooming behavior GO:0007625 6 5 0,000 0,01304775 0,14400408 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,01304775 0,14334653 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,01304775 0,14269496 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01304775 0,14204928 ! response to protozoan GO:0001562 10 5 0,000 0,01304775 0,14140942 ! positive regulation of glycolysis GO:0045821 14 5 0,000 0,01304775 0,14077529 ! lymph vessel development GO:0001945 10 5 0,000 0,01304775 0,14014683 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,01304775 0,13952396 ! endochondral ossification GO:0001958 16 5 0,000 0,01304775 0,1389066 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,01304775 0,13829467 ! parathyroid gland development GO:0060017 13 5 0,000 0,01304775 0,13768812 ! anagen GO:0042640 6 5 0,000 0,01304775 0,13708686 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,01304775 0,13649083 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,01304775 0,13589996 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,01304775 0,13531418 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,01304775 0,13473344 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,01304775 0,13415765 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,01304775 0,13358677 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,01304775 0,13302072 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,01304775 0,13245945 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,01304775 0,1319029 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,01304775 0,13135101 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,01304775 0,13080371 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,01304775 0,13026096 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,01304775 0,12972269 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,01304775 0,12918885 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,01304775 0,12865939 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,01304775 0,12813425 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 0,01304775 0,12761338 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,01304775 0,12709672 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,01304775 0,12658424 ! histidine catabolic process GO:0006548 6 5 0,000 0,01304775 0,12607587 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,01304775 0,12557156 ! valine metabolic process GO:0006573 10 5 0,000 0,01304775 0,12507128 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,01304775 0,12457496 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,01304775 0,12408257 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,01304775 0,12359406 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,01304775 0,12310937 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,01304775 0,12262848 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,01304775 0,12215132 ! polyol catabolic process GO:0046174 7 5 0,000 0,01304775 0,12167787 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,01304775 0,12120807 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,01304775 0,12074189 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,01304775 0,12027927 ! muscle cell migration GO:0014812 8 5 0,000 0,01304775 0,11982019 ! mitochondrial fission GO:0000266 8 5 0,000 0,01304775 0,1193646 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,01304775 0,11891246 ! mRNA transcription GO:0009299 9 5 0,000 0,01304775 0,11846374 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,01304775 0,11801839 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,01304775 0,11757637 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,01304775 0,11713765 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,01304775 0,1167022 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,01304775 0,11626996 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,01304775 0,11584092 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,01304775 0,11541504 ! response to food GO:0032094 6 5 0,000 0,01304775 0,11499227 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,01304775 0,11457259 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,01304775 0,11415597 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,01304775 0,11374236 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01304775 0,11333173 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,01304775 0,11292407 ! forebrain neuron development GO:0021884 13 5 0,000 0,01304775 0,11251932 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,01304775 0,11211747 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,01304775 0,11171847 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,01304775 0,11132231 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01304775 0,11092894 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,01304775 0,11053835 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,01304775 0,11015049 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01304775 0,10976535 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,01304775 0,10938289 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,01304775 0,10900309 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,01304775 0,10862592 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,01304775 0,10825135 ! basic amino acid transport GO:0015802 11 5 0,000 0,01304775 0,10787935 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,01304775 0,1075099 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,01304775 0,10714297 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01304775 0,10677854 ! depyrimidination GO:0045008 10 5 0,000 0,01304775 0,10641658 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,01304775 0,10605706 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01304775 0,10569997 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,01304775 0,10534527 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,01304775 0,10499294 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 0,01304775 0,10464297 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,01304775 0,10429532 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01304775 0,10394997 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,01304775 0,1036069 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,01304775 0,10326609 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,01304775 0,10292751 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,01304775 0,10259115 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,01304775 0,10225697 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01304775 0,10192497 ! response to arsenic GO:0046685 10 5 0,000 0,01304775 0,10159511 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,01304775 0,10126739 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,01304775 0,10094177 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,01304775 0,10061824 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,01304775 0,10029677 ! response to cadmium ion GO:0046686 7 5 0,000 0,01304775 0,09997736 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,01304775 0,09965997 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,01304775 0,09934459 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,01304775 0,0990312 ! decidualization GO:0046697 11 5 0,000 0,01304775 0,09871978 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,01304775 0,09841031 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,01304775 0,09810278 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,01304775 0,09779717 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,01304775 0,09749345 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,01304775 0,09719161 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,01304775 0,09689164 ! neural tube patterning GO:0021532 7 5 0,000 0,01304775 0,09659351 ! embryonic cleavage GO:0040016 6 5 0,000 0,01304775 0,09629721 ! peroxisome fission GO:0016559 5 5 0,000 0,01304775 0,09600272 ! histone demethylation GO:0016577 10 5 0,000 0,01304775 0,09571003 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,01304775 0,09541912 ! mitotic recombination GO:0006312 9 5 0,000 0,01304775 0,09512997 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,01304775 0,09484257 ! metaphase plate congression GO:0051310 7 5 0,000 0,01304775 0,0945569 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01304775 0,09427294 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,01304775 0,09399069 ! enteric nervous system development GO:0048484 8 5 0,000 0,01304775 0,09371012 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,01304775 0,09343122 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,01304775 0,09315398 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,01304775 0,09287837 ! muscle cell proliferation GO:0033002 11 5 0,000 0,01304775 0,0926044 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,01304775 0,09233203 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,01304775 0,09206126 ! plasminogen activation GO:0031639 5 5 0,000 0,01304775 0,09179208 ! B cell homeostasis GO:0001782 13 5 0,000 0,01304775 0,09152446 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,01304775 0,0912584 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,01304775 0,09099389 ! metaphase GO:0051323 8 5 0,000 0,01304775 0,0907309 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,01304775 0,09046943 ! cellular response to nutrient GO:0031670 8 5 0,000 0,01304775 0,09020946 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,01304775 0,08995098 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,01304775 0,08969397 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,01304775 0,08943843 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,01304775 0,08918435 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,01304775 0,0889317 ! response to redox state GO:0051775 5 5 0,000 0,01304775 0,08868048 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,01304775 0,08843068 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,01304775 0,08818228 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,01304775 0,08793527 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,01304775 0,08768964 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01304775 0,08744538 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,01304775 0,08720247 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01304775 0,08696092 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,01304775 0,08672069 ! striatum development GO:0021756 9 5 0,000 0,01304775 0,08648179 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,01304775 0,0862442 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,01304775 0,08600792 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,01304775 0,08577292 ! glial cell migration GO:0008347 11 5 0,000 0,01304775 0,08553921 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,01304775 0,08530677 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,01304775 0,08507558 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,01304775 0,08484565 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,01304775 0,08461696 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,01304775 0,08438949 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,01304775 0,08416325 ! neuroprotection GO:0043526 6 5 0,000 0,01304775 0,08393821 ! neural plate development GO:0001840 8 5 0,000 0,01304775 0,08371437 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,01304775 0,08349173 ! regulation of sensory perception GO:0051931 7 5 0,000 0,01304775 0,08327027 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,01304775 0,08304997 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,01304775 0,08283085 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,01304775 0,08261287 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,01304775 0,08239604 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,01304775 0,08218034 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,01304775 0,08196577 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,01304775 0,08175232 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,01304775 0,08153998 ! spindle assembly GO:0051225 6 5 0,000 0,01304775 0,08132873 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,01304775 0,08111858 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,01304775 0,08090951 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,01304775 0,08070152 ! drug metabolic process GO:0017144 6 5 0,000 0,01304775 0,08049459 ! stem cell division GO:0017145 11 5 0,000 0,01304775 0,08028872 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,01304775 0,0800839 ! organ regeneration GO:0031100 7 5 0,000 0,01304775 0,07988013 ! carnitine metabolic process GO:0009437 7 5 0,000 0,01304775 0,07967739 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,01304775 0,07947567 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,01304775 0,07927498 ! secondary metabolic process GO:0019748 116 66 1,000 0,01307392 0,07923391 ! cell projection assembly GO:0030031 120 66 1,000 0,01307392 0,07903483 ! lung development GO:0030324 144 67 1,000 0,01345351 0,08112567 ! chromosome segregation GO:0007059 113 67 1,000 0,01345351 0,08092286 ! homeostasis of number of cells GO:0048872 114 67 1,000 0,01345351 0,08072106 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 1,000 0,01345351 0,08052026 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 1,000 0,01383786 0,0826151 ! regulation of lipase activity GO:0060191 130 68 1,000 0,01383786 0,08241061 ! protein maturation by peptide bond cleavage GO:0051605 105 68 1,000 0,01383786 0,08220713 ! coenzyme biosynthetic process GO:0009108 102 69 1,000 0,01422694 0,08431041 ! respiratory tube development GO:0030323 150 70 1,000 0,01462074 0,08643121 ! respiratory system development GO:0060541 153 72 1,000 0,01542236 0,09094654 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,01563706 0,0919872 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,01563706 0,09176284 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,01563706 0,09153957 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,01563706 0,09131739 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,01563706 0,09109628 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,01563706 0,09087624 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,01563706 0,09065726 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,01563706 0,09043934 ! sleep GO:0030431 13 6 0,000 0,01563706 0,09022246 ! response to oxygen radical GO:0000305 11 6 0,000 0,01563706 0,09000661 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,01563706 0,0897918 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,01563706 0,08957801 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,01563706 0,08936524 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,01563706 0,08915347 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,01563706 0,08894271 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,01563706 0,08873293 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,01563706 0,08852415 ! forebrain regionalization GO:0021871 8 6 0,000 0,01563706 0,08831635 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,01563706 0,08810952 ! male meiosis GO:0007140 7 6 0,000 0,01563706 0,08790365 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,01563706 0,08769875 ! response to zinc ion GO:0010043 9 6 0,000 0,01563706 0,0874948 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,01563706 0,0872918 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,01563706 0,08708973 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,01563706 0,0868886 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,01563706 0,0866884 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,01563706 0,08648911 ! malate metabolic process GO:0006108 11 6 0,000 0,01563706 0,08629074 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,01563706 0,08609328 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,01563706 0,08589672 ! protein refolding GO:0042026 15 6 0,000 0,01563706 0,08570106 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,01563706 0,08550628 ! opsonization GO:0008228 8 6 0,000 0,01563706 0,08531239 ! mating behavior GO:0007617 7 6 0,000 0,01563706 0,08511938 ! neuron remodeling GO:0016322 15 6 0,000 0,01563706 0,08492723 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,01563706 0,08473596 ! equilibrioception GO:0050957 14 6 0,000 0,01563706 0,08454554 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,01563706 0,08435597 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,01563706 0,08416726 ! photoreceptor cell development GO:0042461 10 6 0,000 0,01563706 0,08397938 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,01563706 0,08379235 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,01563706 0,08360614 ! response to interferon-gamma GO:0034341 15 6 0,000 0,01563706 0,08342076 ! toxin metabolic process GO:0009404 11 6 0,000 0,01563706 0,0832362 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,01563706 0,08305246 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,01563706 0,08286952 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,01563706 0,08268739 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,01563706 0,08250606 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,01563706 0,08232552 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,01563706 0,08214577 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,01563706 0,08196681 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,01563706 0,08178862 ! thymic T cell selection GO:0045061 12 6 0,000 0,01563706 0,0816112 ! protein lipoylation GO:0009249 10 6 0,000 0,01563706 0,08143455 ! cysteine metabolic process GO:0006534 10 6 0,000 0,01563706 0,08125867 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,01563706 0,08108354 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,01563706 0,08090917 ! glutamate catabolic process GO:0006538 10 6 0,000 0,01563706 0,08073555 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,01563706 0,08056266 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,01563706 0,08039052 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,01563706 0,08021911 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,01563706 0,08004843 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,01563706 0,07987848 ! hyperosmotic response GO:0006972 9 6 0,000 0,01563706 0,07970925 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,01563706 0,07954073 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,01563706 0,07937292 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,01563706 0,07920582 ! urea metabolic process GO:0019627 7 6 0,000 0,01563706 0,07903942 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,01563706 0,07887372 ! neutrophil activation GO:0042119 8 6 0,000 0,01563706 0,07870871 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,01563706 0,07854439 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,01563706 0,07838076 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,01563706 0,07821781 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,01563706 0,07805553 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,01563706 0,07789392 ! neuron apoptosis GO:0051402 9 6 0,000 0,01563706 0,07773298 ! nucleoside salvage GO:0043174 9 6 0,000 0,01563706 0,07757271 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,01563706 0,0774131 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,01563706 0,07725414 ! T cell mediated immunity GO:0002456 16 6 0,000 0,01563706 0,07709583 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,01563706 0,07693817 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 0,01563706 0,07678115 ! carnitine transport GO:0015879 10 6 0,000 0,01563706 0,07662477 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,01563706 0,07646903 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01563706 0,07631392 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,01563706 0,07615944 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,01563706 0,07600558 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,01563706 0,07585235 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,01563706 0,07569973 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,01563706 0,07554772 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,01563706 0,07539632 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,01563706 0,07524553 ! establishment of spindle localization GO:0051293 12 6 0,000 0,01563706 0,07509534 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,01563706 0,07494575 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,01563706 0,07479675 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,01563706 0,07464834 ! neural nucleus development GO:0048857 14 6 0,000 0,01563706 0,07450052 ! response to UV-C GO:0010225 11 6 0,000 0,01563706 0,07435329 ! astrocyte development GO:0014002 15 6 0,000 0,01563706 0,07420664 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,01563706 0,07406056 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,01563706 0,07391506 ! interaction with symbiont GO:0051702 13 6 0,000 0,01563706 0,07377013 ! regulation of dendrite development GO:0050773 16 6 0,000 0,01563706 0,07362576 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,01563706 0,07348196 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,01563706 0,07333872 ! response to copper ion GO:0046688 10 6 0,000 0,01563706 0,07319604 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,01563706 0,07305391 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,01563706 0,07291233 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,01563706 0,0727713 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,01563706 0,07263082 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,01563706 0,07249088 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,01563706 0,07235147 ! hair follicle maturation GO:0048820 7 6 0,000 0,01563706 0,0722126 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,01563706 0,07207426 ! Schwann cell development GO:0014044 15 6 0,000 0,01563706 0,07193645 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,01563706 0,07179917 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,01563706 0,07166241 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,01563706 0,07152617 ! subpallium development GO:0021544 10 6 0,000 0,01563706 0,07139044 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,01563706 0,07125524 ! histone ubiquitination GO:0016574 8 6 0,000 0,01563706 0,07112054 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,01563706 0,07098635 ! maintenance of organ identity GO:0048496 9 6 0,000 0,01563706 0,07085266 ! G2 phase GO:0051319 16 6 0,000 0,01563706 0,07071948 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,01563706 0,0705868 ! establishment of planar polarity GO:0001736 7 6 0,000 0,01563706 0,07045461 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,01563706 0,07032292 ! membrane to membrane docking GO:0022614 14 6 0,000 0,01563706 0,07019172 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,01563706 0,07006101 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,01563706 0,06993079 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,01563706 0,06980105 ! receptor internalization GO:0031623 10 6 0,000 0,01563706 0,06967179 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,01563706 0,069543 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,01563706 0,06941469 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01563706 0,06928686 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,01563706 0,06915949 ! protein deubiquitination GO:0016579 14 6 0,000 0,01563706 0,0690326 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 0,01563706 0,06890616 ! protein destabilization GO:0031648 9 6 0,000 0,01563706 0,06878019 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,01563706 0,06865468 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,01563706 0,06852963 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,01563706 0,06840503 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,01563706 0,06828088 ! progesterone metabolic process GO:0042448 10 6 0,000 0,01563706 0,06815718 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,01563706 0,06803393 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,01563706 0,06791113 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,01563706 0,06778876 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,01563706 0,06766684 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,01563706 0,06754536 ! determination of adult lifespan GO:0008340 15 6 0,000 0,01563706 0,06742431 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,01563706 0,06730369 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,01563706 0,06718351 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,01563706 0,06706375 ! catecholamine transport GO:0051937 9 6 0,000 0,01563706 0,06694442 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,01563706 0,06682551 ! sensory cilium assembly GO:0035058 10 6 0,000 0,01563706 0,06670703 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,01563706 0,06658896 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,01563706 0,06647132 ! maternal placenta development GO:0001893 12 6 0,000 0,01563706 0,06635408 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,01563706 0,06623726 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,01563706 0,06612085 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,01563706 0,06600485 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,01563706 0,06588925 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,01563706 0,06577406 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,01563706 0,06565927 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,01563706 0,06554489 ! regulation of blood pressure GO:0008217 125 73 1,000 0,01583012 0,06623874 ! regulation of transcription factor activity GO:0051090 126 74 1,000 0,01624249 0,06784625 GO:0090046|regulation of transcription regulator activity, ! exocytosis GO:0006887 133 74 1,000 0,01624249 0,06772866 ! steroid biosynthetic process GO:0006694 131 76 1,000 0,01708094 0,07110163 ! tRNA transcription GO:0009304 14 7 0,000 0,01821966 0,07571071 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,01821966 0,07558017 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,01821966 0,07545009 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,01821966 0,07532045 ! regulation of helicase activity GO:0051095 15 7 0,000 0,01821966 0,07519125 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,01821966 0,0750625 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,01821966 0,07493419 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,01821966 0,07480631 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,01821966 0,07467888 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,01821966 0,07455187 ! prostate gland development GO:0030850 13 7 0,000 0,01821966 0,0744253 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,01821966 0,07429915 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,01821966 0,07417344 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,01821966 0,07404814 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,01821966 0,07392327 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01821966 0,07379882 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,01821966 0,07367479 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,01821966 0,07355117 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 0,01821966 0,07342797 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,01821966 0,07330518 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,01821966 0,07318281 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,01821966 0,07306083 ! glycolipid transport GO:0046836 10 7 0,000 0,01821966 0,07293927 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,01821966 0,07281811 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,01821966 0,07269735 ! neuron adhesion GO:0007158 12 7 0,000 0,01821966 0,07257699 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,01821966 0,07245703 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,01821966 0,07233746 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,01821966 0,07221829 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,01821966 0,07209951 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,01821966 0,07198112 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,01821966 0,07186312 ! mRNA stabilization GO:0048255 18 7 0,000 0,01821966 0,0717455 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,01821966 0,07162827 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,01821966 0,07151142 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,01821966 0,07139495 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,01821966 0,07127886 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,01821966 0,07116315 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,01821966 0,07104781 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,01821966 0,07093285 ! lipoprotein transport GO:0042953 14 7 0,000 0,01821966 0,07081826 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,01821966 0,07070403 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,01821966 0,07059018 ! rhythmic behavior GO:0007622 15 7 0,000 0,01821966 0,07047669 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,01821966 0,07036356 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,01821966 0,0702508 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,01821966 0,0701384 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,01821966 0,07002636 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,01821966 0,06991467 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,01821966 0,06980334 ! mechanosensory behavior GO:0007638 14 7 0,000 0,01821966 0,06969237 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,01821966 0,06958175 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,01821966 0,06947147 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,01821966 0,06936155 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01821966 0,06925198 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,01821966 0,06914274 ! spinal cord patterning GO:0021511 13 7 0,000 0,01821966 0,06903386 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,01821966 0,06892531 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,01821966 0,06881711 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,01821966 0,06870925 ! adrenal gland development GO:0030325 17 7 0,000 0,01821966 0,06860172 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,01821966 0,06849453 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,01821966 0,06838768 ! ovulation GO:0030728 9 7 0,000 0,01821966 0,06828115 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,01821966 0,06817496 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,01821966 0,0680691 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,01821966 0,06796357 ! microtubule nucleation GO:0007020 20 7 0,000 0,01821966 0,06785836 ! proline biosynthetic process GO:0006561 10 7 0,000 0,01821966 0,06775348 ! thyroid hormone generation GO:0006590 13 7 0,000 0,01821966 0,06764892 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,01821966 0,06754468 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,01821966 0,06744077 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,01821966 0,06733717 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,01821966 0,0672339 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,01821966 0,06713093 ! galactose metabolic process GO:0006012 13 7 0,000 0,01821966 0,06702829 ! response to dietary excess GO:0002021 8 7 0,000 0,01821966 0,06692595 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,01821966 0,06682393 ! intracellular pH reduction GO:0051452 11 7 0,000 0,01821966 0,06672222 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,01821966 0,06662082 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,01821966 0,06651973 ! organ growth GO:0035265 15 7 0,000 0,01821966 0,06641894 ! purine salvage GO:0043101 10 7 0,000 0,01821966 0,06631846 ! nucleoside transport GO:0015858 8 7 0,000 0,01821966 0,06621828 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,01821966 0,0661184 ! parturition GO:0007567 14 7 0,000 0,01821966 0,06601883 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,01821966 0,06591955 ! rRNA modification GO:0000154 14 7 0,000 0,01821966 0,06582057 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,01821966 0,06572189 ! spindle checkpoint GO:0031577 15 7 0,000 0,01821966 0,0656235 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,01821966 0,06552541 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,01821966 0,06542761 ! macrophage differentiation GO:0030225 11 7 0,000 0,01821966 0,0653301 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,01821966 0,06523289 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,01821966 0,06513596 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,01821966 0,06503932 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,01821966 0,06494296 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 0,01821966 0,06484689 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,01821966 0,06475111 ! fibrinolysis GO:0042730 10 7 0,000 0,01821966 0,06465561 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,01821966 0,06456038 ! eating behavior GO:0042755 7 7 0,000 0,01821966 0,06446544 ! B cell lineage commitment GO:0002326 21 7 0,000 0,01821966 0,06437078 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,01821966 0,06427639 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,01821966 0,06418228 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,01821966 0,06408845 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,01821966 0,06399489 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,01821966 0,0639016 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,01821966 0,06380859 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,01821966 0,06371584 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,01821966 0,06362337 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,01821966 0,06353116 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,01821966 0,06343922 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,01821966 0,06334754 ! regulation of meiosis GO:0040020 12 7 0,000 0,01821966 0,06325613 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,01821966 0,06316499 ! T cell lineage commitment GO:0002360 16 7 0,000 0,01821966 0,0630741 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,01821966 0,06298348 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,01821966 0,06289311 ! oxygen homeostasis GO:0032364 12 7 0,000 0,01821966 0,06280301 ! transcription termination GO:0006353 13 7 0,000 0,01821966 0,06271316 ! response to tumor cell GO:0002347 13 7 0,000 0,01821966 0,06262357 ! regulation of respiratory burst GO:0060263 11 7 0,000 0,01821966 0,06253424 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,01821966 0,06244516 ! anaphase GO:0051322 17 7 0,000 0,01821966 0,06235633 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,01821966 0,06226776 ! axonal fasciculation GO:0007413 18 7 0,000 0,01821966 0,06217943 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,01821966 0,06209136 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,01821966 0,06200354 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,01821966 0,06191596 ! diuresis GO:0030146 12 7 0,000 0,01821966 0,06182863 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,01821966 0,06174155 ! thiamin metabolic process GO:0006772 7 7 0,000 0,01821966 0,06165471 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,01821966 0,06156812 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,01821966 0,06148177 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,01821966 0,06139566 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,01821966 0,06130979 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,01821966 0,06122416 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,01821966 0,06113877 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,01821966 0,06105362 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,01821966 0,06096871 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,01821966 0,06088403 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,01821966 0,06079958 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,01821966 0,06071537 ! lymph node development GO:0048535 10 7 0,000 0,01821966 0,0606314 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,01821966 0,06054765 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,01821966 0,06046414 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,01821966 0,06038085 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,01821966 0,0602978 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,01821966 0,06021497 ! adult feeding behavior GO:0008343 9 7 0,000 0,01821966 0,06013237 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,01821966 0,06005 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,01821966 0,05996785 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,01821966 0,05988593 ! muscle adaptation GO:0043500 14 7 0,000 0,01821966 0,05980423 ! embryonic heart tube development GO:0035050 10 7 0,000 0,01821966 0,05972275 ! retina homeostasis GO:0001895 12 7 0,000 0,01821966 0,0596415 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,01821966 0,05956046 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,01821966 0,05947965 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,01821966 0,05939905 ! protein prenylation GO:0018342 18 7 0,000 0,01821966 0,05931867 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,01821966 0,05923851 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,01821966 0,05915857 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,01821966 0,05907884 ! positive regulation of phosphorylation GO:0042327 129 79 1,000 0,01837248 0,05949421 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 1,000 0,0192558 0,06227076 GO:0045937|positive regulation of phosphate metabolic process, ! response to hypoxia GO:0001666 171 81 1,000 0,0192558 0,06218717 ! regulation of neuron differentiation GO:0045664 167 81 1,000 0,0192558 0,06210381 ! cholesterol metabolic process GO:0008203 136 82 1,000 0,01970406 0,06346447 ! cellular response to hormone stimulus GO:0032870 167 82 1,000 0,01970406 0,06337963 ! response to oxygen levels GO:0070482 176 83 1,000 0,02015669 0,064749 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,02079557 0,06671219 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,02079557 0,06662335 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,02079557 0,06653476 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,02079557 0,0664464 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,02079557 0,06635828 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,02079557 0,06627038 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,02079557 0,06618272 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,02079557 0,0660953 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,02079557 0,0660081 ! meiotic prophase I GO:0007128 13 8 0,000 0,02079557 0,06592113 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,02079557 0,06583439 ! oligopeptide transport GO:0006857 15 8 0,000 0,02079557 0,06574788 ! UTP metabolic process GO:0046051 8 8 0,000 0,02079557 0,0656616 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,02079557 0,06557554 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,02079557 0,06548971 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,02079557 0,0654041 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,02079557 0,06531872 ! succinate metabolic process GO:0006105 14 8 0,000 0,02079557 0,06523356 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,02079557 0,06514862 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,02079557 0,0650639 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,02079557 0,0649794 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,02079557 0,06489512 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,02079557 0,06481106 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,02079557 0,06472722 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,02079557 0,06464359 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,02079557 0,06456018 ! reflex GO:0060004 16 8 0,000 0,02079557 0,06447698 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,02079557 0,064394 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,02079557 0,06431123 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,02079557 0,06422868 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,02079557 0,06414633 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,02079557 0,0640642 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,02079557 0,06398228 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,02079557 0,06390056 ! pigment granule organization GO:0048753 16 8 0,000 0,02079557 0,06381906 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,02079557 0,06373776 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,02079557 0,06365667 ! astrocyte differentiation GO:0048708 18 8 0,000 0,02079557 0,06357578 ! histidine metabolic process GO:0006547 16 8 0,000 0,02079557 0,0634951 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,02079557 0,06341463 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,02079557 0,06333435 ! glycine catabolic process GO:0006546 13 8 0,000 0,02079557 0,06325429 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,02079557 0,06317442 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,02079557 0,06309475 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 12 8 0,000 0,02079557 0,06301529 ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,02079557 0,06293602 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,02079557 0,06285696 ! melanin metabolic process GO:0006582 15 8 0,000 0,02079557 0,06277809 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,02079557 0,06269942 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,02079557 0,06262095 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,02079557 0,06254267 ! macrophage activation GO:0042116 12 8 0,000 0,02079557 0,06246459 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,02079557 0,06238671 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,02079557 0,06230902 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,02079557 0,06223152 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,02079557 0,06215421 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,02079557 0,0620771 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,02079557 0,06200017 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,02079557 0,06192344 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,02079557 0,0618469 ! osteoblast development GO:0002076 16 8 0,000 0,02079557 0,06177054 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,02079557 0,06169438 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,02079557 0,0616184 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,02079557 0,06154261 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,02079557 0,061467 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,02079557 0,06139158 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,02079557 0,06131635 ! response to UV-B GO:0010224 16 8 0,000 0,02079557 0,0612413 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,02079557 0,06116643 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,02079557 0,06109175 ! intermediate filament organization GO:0045109 12 8 0,000 0,02079557 0,06101724 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,02079557 0,06094292 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,02079557 0,06086878 ! cellular extravasation GO:0045123 12 8 0,000 0,02079557 0,06079482 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,02079557 0,06072104 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,02079557 0,06064744 ! response to antibiotic GO:0046677 11 8 0,000 0,02079557 0,06057402 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,02079557 0,06050077 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,02079557 0,0604277 ! DNA topological change GO:0006265 12 8 0,000 0,02079557 0,06035481 ! response to tropane GO:0014073 15 8 0,000 0,02079557 0,0602821 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,02079557 0,06020955 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 0,000 0,02079557 0,06013719 ! melanosome transport GO:0032402 13 8 0,000 0,02079557 0,06006499 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,02079557 0,05999297 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,02079557 0,05992113 ! mast cell activation GO:0045576 14 8 0,000 0,02079557 0,05984945 ! multicellular organismal aging GO:0010259 18 8 0,000 0,02079557 0,05977794 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,02079557 0,05970661 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,02079557 0,05963545 ! nucleosome disassembly GO:0006337 14 8 0,000 0,02079557 0,05956445 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,02079557 0,05949363 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,02079557 0,05942297 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,02079557 0,05935248 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,02079557 0,05928216 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,02079557 0,059212 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,02079557 0,05914201 ! intracellular lipid transport GO:0032365 13 8 0,000 0,02079557 0,05907218 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,02079557 0,05900252 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,02079557 0,05893303 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,02079557 0,05886369 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,02079557 0,05879452 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,02079557 0,05872552 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,02079557 0,05865667 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,02079557 0,05858799 ! hormone catabolic process GO:0042447 17 8 0,000 0,02079557 0,05851946 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,02079557 0,0584511 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,02079557 0,05838289 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,02079557 0,05831485 ! ATP catabolic process GO:0006200 11 8 0,000 0,02079557 0,05824696 ! blastocyst growth GO:0001832 19 8 0,000 0,02079557 0,05817923 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,02079557 0,05811166 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,02079557 0,05804425 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,02079557 0,05797699 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,02079557 0,05790988 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,02079557 0,05784294 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,02079557 0,05777614 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,02079557 0,0577095 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,02079557 0,05764302 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,02079557 0,05757669 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,02079557 0,05751051 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,02079557 0,05744448 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,02079557 0,0573786 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,02079557 0,05731287 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,02079557 0,0572473 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,02079557 0,05718187 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,02079557 0,0571166 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,02079557 0,05705147 ! oxidative phosphorylation GO:0006119 133 86 1,000 0,02154056 0,05902801 ! regulation of DNA binding GO:0051101 155 88 1,000 0,02248453 0,06154469 ! regulation of cell morphogenesis GO:0022604 215 89 1,000 0,02296286 0,06278255 ! regulation of developmental growth GO:0048638 15 9 0,000 0,02336481 0,06380899 ! axon extension GO:0048675 15 9 0,000 0,02336481 0,06373665 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,02336481 0,06366447 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,02336481 0,06359245 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,02336481 0,06352059 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,02336481 0,0634489 ! associative learning GO:0008306 20 9 0,000 0,02336481 0,06337737 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,02336481 0,06330599 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,02336481 0,06323478 ! phosphate transport GO:0006817 19 9 0,000 0,02336481 0,06316373 ! reproductive behavior GO:0019098 19 9 0,000 0,02336481 0,06309284 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,02336481 0,06302211 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,02336481 0,06295154 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,02336481 0,06288112 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,02336481 0,06281086 ! GTP metabolic process GO:0046039 9 9 0,000 0,02336481 0,06274076 ! RNA methylation GO:0001510 15 9 0,000 0,02336481 0,06267082 ! elastic fiber assembly GO:0048251 15 9 0,000 0,02336481 0,06260103 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,02336481 0,06253139 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,02336481 0,06246191 ! artery development GO:0060840 24 9 0,000 0,02336481 0,06239259 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,02336481 0,06232342 ! regulation of glycolysis GO:0006110 21 9 0,000 0,02336481 0,0622544 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,02336481 0,06218553 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,02336481 0,06211682 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,02336481 0,06204826 ! chemosensory behavior GO:0007635 20 9 0,000 0,02336481 0,06197985 ! microtubule bundle formation GO:0001578 21 9 0,000 0,02336481 0,06191159 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,02336481 0,06184348 ! leukocyte degranulation GO:0043299 16 9 0,000 0,02336481 0,06177552 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,02336481 0,06170771 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,02336481 0,06164005 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,02336481 0,06157253 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,02336481 0,06150517 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,02336481 0,06143795 ! protein targeting to ER GO:0045047 22 9 0,000 0,02336481 0,06137088 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,02336481 0,06130395 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,02336481 0,06123717 ! T cell selection GO:0045058 23 9 0,000 0,02336481 0,06117054 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,02336481 0,06110405 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,02336481 0,0610377 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,02336481 0,0609715 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,02336481 0,06090544 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,02336481 0,06083953 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,02336481 0,06077375 ! mannose metabolic process GO:0006013 13 9 0,000 0,02336481 0,06070812 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,02336481 0,06064264 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,02336481 0,06057729 ! receptor clustering GO:0043113 18 9 0,000 0,02336481 0,06051208 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,02336481 0,06044701 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,02336481 0,06038209 ! ruffle organization GO:0031529 15 9 0,000 0,02336481 0,0603173 ! retinol metabolic process GO:0042572 18 9 0,000 0,02336481 0,06025265 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,02336481 0,06018814 ! behavioral fear response GO:0001662 22 9 0,000 0,02336481 0,06012377 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,02336481 0,06005953 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,02336481 0,05999544 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,02336481 0,05993147 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 0,02336481 0,05986765 ! protein heterooligomerization GO:0051291 16 9 0,000 0,02336481 0,05980396 ! oligodendrocyte development GO:0014003 10 9 0,000 0,02336481 0,05974041 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,02336481 0,05967699 ! segment specification GO:0007379 13 9 0,000 0,02336481 0,0596137 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,02336481 0,05955055 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,02336481 0,05948754 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,02336481 0,05942465 ! response to amine stimulus GO:0014075 13 9 0,000 0,02336481 0,0593619 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,02336481 0,05929929 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,02336481 0,0592368 ! gas homeostasis GO:0033483 16 9 0,000 0,02336481 0,05917445 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,02336481 0,05911222 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,02336481 0,05905013 ! renal water homeostasis GO:0003091 14 9 0,000 0,02336481 0,05898817 ! postreplication repair GO:0006301 22 9 0,000 0,02336481 0,05892633 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,02336481 0,05886463 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,02336481 0,05880306 ! icosanoid secretion GO:0032309 15 9 0,000 0,02336481 0,05874161 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,02336481 0,0586803 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,02336481 0,05861911 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,02336481 0,05855804 ! regulation of cell division GO:0051302 15 9 0,000 0,02336481 0,05849711 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,02336481 0,0584363 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,02336481 0,05837562 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,02336481 0,05831507 ! sterol catabolic process GO:0016127 11 9 0,000 0,02336481 0,05825464 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,02336481 0,05819433 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,02336481 0,05813415 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,02336481 0,05807409 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,02336481 0,05801416 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,02336481 0,05795435 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,02336481 0,05789467 ! musculoskeletal movement GO:0050881 14 9 0,000 0,02336481 0,05783511 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,02336481 0,05777567 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,02336481 0,05771635 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,02336481 0,05765715 ! purine base metabolic process GO:0006144 21 9 0,000 0,02336481 0,05759808 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,02336481 0,05753912 ! pigment granule transport GO:0051904 17 9 0,000 0,02336481 0,05748029 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,02336481 0,05742158 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,02336481 0,05736298 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,02336481 0,05730451 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,02336481 0,05724615 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,02336481 0,05718792 ! mitochondrion localization GO:0051646 15 9 0,000 0,02336481 0,0571298 ! ossification GO:0001503 188 90 1,000 0,02344538 0,05726862 ! bone development GO:0060348 189 91 1,000 0,02393208 0,05839815 ! sterol metabolic process GO:0016125 152 91 1,000 0,02393208 0,05833898 ! cofactor biosynthetic process GO:0051188 139 91 1,000 0,02393208 0,05827993 ! vitamin metabolic process GO:0006766 139 92 1,000 0,02442291 0,0594151 ! positive regulation of MAP kinase activity GO:0043406 160 93 1,000 0,02491787 0,06055798 ! carbohydrate biosynthetic process GO:0016051 141 93 1,000 0,02491787 0,06049688 ! regulation of membrane potential GO:0042391 164 93 1,000 0,02491787 0,06043589 ! interphase of mitotic cell cycle GO:0051329 209 95 1,000 0,02592006 0,06280329 ! regulation of Rho protein signal transduction GO:0035023 213 95 1,000 0,02592006 0,0627401 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,02592739 0,06269477 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 0,000 0,02592739 0,06263182 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,02592739 0,062569 ! positive regulation of B cell proliferation GO:0030890 16 10 0,000 0,02592739 0,0625063 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,02592739 0,06244374 ! synapsis GO:0007129 13 10 0,000 0,02592739 0,06238129 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,02592739 0,06231897 ! N-glycan processing GO:0006491 20 10 0,000 0,02592739 0,06225678 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,02592739 0,06219471 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,02592739 0,06213276 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,02592739 0,06207094 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,02592739 0,06200924 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 0,02592739 0,06194766 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,02592739 0,0618862 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,02592739 0,06182487 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,02592739 0,06176366 ! androgen metabolic process GO:0008209 17 10 0,000 0,02592739 0,06170256 ! phospholipid efflux GO:0033700 16 10 0,000 0,02592739 0,06164159 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,02592739 0,06158074 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,02592739 0,06152001 ! lung alveolus development GO:0048286 26 10 0,000 0,02592739 0,0614594 ! pathogenesis GO:0009405 13 10 0,000 0,02592739 0,06139891 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,02592739 0,06133854 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,02592739 0,06127828 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,02592739 0,06121815 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,02592739 0,06115813 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,02592739 0,06109823 ! endoderm development GO:0007492 16 10 0,000 0,02592739 0,06103845 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,02592739 0,06097878 ! arginine catabolic process GO:0006527 13 10 0,000 0,02592739 0,06091923 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,02592739 0,0608598 ! proline metabolic process GO:0006560 13 10 0,000 0,02592739 0,06080048 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,02592739 0,06074128 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,02592739 0,06068219 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,02592739 0,06062322 ! V(D)J recombination GO:0033151 28 10 0,000 0,02592739 0,06056436 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,02592739 0,06050562 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,02592739 0,06044699 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,02592739 0,06038847 ! B cell proliferation GO:0042100 18 10 0,000 0,02592739 0,06033007 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,02592739 0,06027178 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,02592739 0,0602136 ! multicellular organism growth GO:0035264 18 10 0,000 0,02592739 0,06015554 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,02592739 0,06009758 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,02592739 0,06003974 ! epithelial cell development GO:0002064 20 10 0,000 0,02592739 0,05998201 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,02592739 0,05992439 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,02592739 0,05986688 ! macroautophagy GO:0016236 17 10 0,000 0,02592739 0,05980948 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,02592739 0,0597522 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,02592739 0,05969502 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,02592739 0,05963795 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,02592739 0,05958099 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 0,02592739 0,05952413 ! copper ion homeostasis GO:0055070 13 10 0,000 0,02592739 0,05946739 ! regulation of bone resorption GO:0045124 25 10 0,000 0,02592739 0,05941075 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,02592739 0,05935423 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,02592739 0,05929781 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,02592739 0,05924149 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,02592739 0,05918529 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,02592739 0,05912919 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,02592739 0,05907319 ! blastoderm segmentation GO:0007350 18 10 0,000 0,02592739 0,05901731 ! response to dsRNA GO:0043331 20 10 0,000 0,02592739 0,05896152 ! DNA ligation GO:0006266 19 10 0,000 0,02592739 0,05890585 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,02592739 0,05885028 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,02592739 0,05879481 ! melanosome localization GO:0032400 16 10 0,000 0,02592739 0,05873945 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,02592739 0,05868419 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,02592739 0,05862903 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,02592739 0,05857398 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,02592739 0,05851904 ! mRNA cleavage GO:0006379 17 10 0,000 0,02592739 0,05846419 ! protein sumoylation GO:0016925 15 10 0,000 0,02592739 0,05840945 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,02592739 0,05835481 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,02592739 0,05830027 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,02592739 0,05824584 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,02592739 0,0581915 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,02592739 0,05813727 ! salivary gland development GO:0007431 27 10 0,000 0,02592739 0,05808314 ! prophase GO:0051324 15 10 0,000 0,02592739 0,05802911 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,02592739 0,05797518 ! apical protein localization GO:0045176 15 10 0,000 0,02592739 0,05792135 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,02592739 0,05786762 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,02592739 0,05781399 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,02592739 0,05776046 ! midbrain development GO:0030901 13 10 0,000 0,02592739 0,05770702 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,02592739 0,05765369 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,02592739 0,05760045 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,02592739 0,05754732 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,02592739 0,05749428 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,02592739 0,05744134 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,02592739 0,05738849 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 0,02592739 0,05733575 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 0,02592739 0,0572831 ! oocyte development GO:0048599 17 10 0,000 0,02592739 0,05723054 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,02592739 0,05717809 ! blastocyst formation GO:0001825 17 10 0,000 0,02592739 0,05712573 ! cerebellar cortex development GO:0021695 15 10 0,000 0,02592739 0,05707346 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,02592739 0,05702129 ! activation of innate immune response GO:0002218 12 10 0,000 0,02592739 0,05696922 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,02592739 0,05691724 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,02592739 0,05686535 ! response to nicotine GO:0035094 20 10 0,000 0,02592739 0,05681356 ! establishment of cell polarity GO:0030010 16 10 0,000 0,02592739 0,05676187 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,02592739 0,05671027 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,02592739 0,05665876 ! interphase GO:0051325 213 98 1,000 0,02745364 0,05993962 ! skeletal muscle tissue development GO:0007519 186 99 1,000 0,02797282 0,06101777 GO:0060538|skeletal muscle organ development, ! negative regulation of muscle development GO:0048635 20 11 0,000 0,02848333 0,06207508 ! respiratory burst GO:0045730 17 11 0,000 0,02848333 0,0620189 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,02848333 0,06196283 ! neuron fate specification GO:0048665 17 11 0,000 0,02848333 0,06190685 ! telencephalon cell migration GO:0022029 20 11 0,000 0,02848333 0,06185098 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,02848333 0,06179521 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,02848333 0,06173954 ! thyroid gland development GO:0030878 26 11 0,000 0,02848333 0,06168397 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,02848333 0,0616285 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,02848333 0,06157312 ! response to pain GO:0048265 24 11 0,000 0,02848333 0,06151785 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,02848333 0,06146268 ! T cell proliferation GO:0042098 26 11 0,000 0,02848333 0,06140761 ! blood vessel remodeling GO:0001974 29 11 0,000 0,02848333 0,06135263 ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,02848333 0,06129775 ! bone resorption GO:0045453 16 11 0,000 0,02848333 0,06124297 ! ventral spinal cord development GO:0021517 21 11 0,000 0,02848333 0,06118829 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,02848333 0,06113371 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,02848333 0,06107922 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,02848333 0,06102483 ! melanocyte differentiation GO:0030318 21 11 0,000 0,02848333 0,06097054 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,02848333 0,06091634 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,02848333 0,06086225 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,02848333 0,06080824 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,02848333 0,06075433 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,02848333 0,06070052 ! lipid digestion GO:0044241 18 11 0,000 0,02848333 0,0606468 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,02848333 0,06059318 ! UV protection GO:0009650 19 11 0,000 0,02848333 0,06053965 ! adult heart development GO:0007512 14 11 0,000 0,02848333 0,06048622 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,02848333 0,06043288 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,02848333 0,06037964 ! temperature homeostasis GO:0001659 17 11 0,000 0,02848333 0,06032649 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,02848333 0,06027343 ! negative regulation of ossification GO:0030279 26 11 0,000 0,02848333 0,06022046 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,02848333 0,06016759 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,02848333 0,06011481 ! regulation of organ growth GO:0046620 13 11 0,000 0,02848333 0,06006213 ! pigment granule localization GO:0051875 20 11 0,000 0,02848333 0,06000953 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,02848333 0,05995703 ! embryonic axis specification GO:0000578 18 11 0,000 0,02848333 0,05990462 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,02848333 0,0598523 ! snRNA metabolic process GO:0016073 24 11 0,000 0,02848333 0,05980008 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,02848333 0,05974794 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,02848333 0,0596959 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,02848333 0,05964394 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,02848333 0,05959208 ! zymogen activation GO:0031638 15 11 0,000 0,02848333 0,0595403 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,02848333 0,05948862 ! neuroblast proliferation GO:0007405 24 11 0,000 0,02848333 0,05943702 ! nucleosome positioning GO:0016584 15 11 0,000 0,02848333 0,05938552 ! regulation of isotype switching GO:0045191 22 11 0,000 0,02848333 0,0593341 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,02848333 0,05928278 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,02848333 0,05923154 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,02848333 0,05918039 ! acid secretion GO:0046717 18 11 0,000 0,02848333 0,05912933 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,02848333 0,05907835 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,02848333 0,05902747 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,02848333 0,05897667 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,02848333 0,05892596 ! oocyte differentiation GO:0009994 18 11 0,000 0,02848333 0,05887533 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,02848333 0,0588248 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,02848333 0,05877435 ! cholesterol efflux GO:0033344 19 11 0,000 0,02848333 0,05872398 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,02848333 0,05867371 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,02848333 0,05862351 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,02848333 0,05857341 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,02848333 0,05852339 ! embryonic gut development GO:0048566 15 11 0,000 0,02848333 0,05847345 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,02848333 0,0584236 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,02848333 0,05837384 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,02848333 0,05832416 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,02848333 0,05827456 ! defense response to fungus GO:0050832 13 11 0,000 0,02848333 0,05822505 ! developmental induction GO:0031128 19 11 0,000 0,02848333 0,05817563 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,02848333 0,05812628 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,02848333 0,05807702 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,02848333 0,05802785 ! sequestering of metal ion GO:0051238 14 11 0,000 0,02848333 0,05797875 ! lamellipodium assembly GO:0030032 20 11 0,000 0,02848333 0,05792974 ! regulation of embryonic development GO:0045995 27 11 0,000 0,02848333 0,05788082 ! nucleus localization GO:0051647 19 11 0,000 0,02848333 0,05783197 ! regulation of synapse organization GO:0050807 17 11 0,000 0,02848333 0,05778321 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,03103265 0,0629019 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,03103265 0,06284895 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 0,03103265 0,06279609 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,03103265 0,06274332 ! virus-host interaction GO:0019048 29 12 0,000 0,03103265 0,06269064 ! regulation of B cell proliferation GO:0030888 20 12 0,000 0,03103265 0,06263805 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,03103265 0,06258554 ! cartilage condensation GO:0001502 20 12 0,000 0,03103265 0,06253312 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,03103265 0,0624808 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,03103265 0,06242855 ! protein complex disassembly GO:0043241 27 12 0,000 0,03103265 0,0623764 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,03103265 0,06232433 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,03103265 0,06227235 ! hippocampus development GO:0021766 26 12 0,000 0,03103265 0,06222046 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 0,03103265 0,06216865 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,03103265 0,06211693 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,03103265 0,0620653 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,03103265 0,06201375 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,03103265 0,06196228 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,03103265 0,0619109 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,03103265 0,06185961 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,03103265 0,0618084 ! drug transport GO:0015893 16 12 0,000 0,03103265 0,06175728 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,03103265 0,06170624 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,03103265 0,06165529 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,03103265 0,06160442 ! polyamine metabolic process GO:0006595 17 12 0,000 0,03103265 0,06155363 ! focal adhesion formation GO:0048041 35 12 0,000 0,03103265 0,06150293 ! mitotic spindle organization GO:0007052 21 12 0,000 0,03103265 0,06145231 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,03103265 0,06140177 ! forebrain cell migration GO:0021885 21 12 0,000 0,03103265 0,06135132 ! asymmetric protein localization GO:0008105 20 12 0,000 0,03103265 0,06130095 ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,03103265 0,06125066 ! entry into host cell GO:0030260 32 12 0,000 0,03103265 0,06120045 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,03103265 0,06115033 ! monoamine transport GO:0015844 18 12 0,000 0,03103265 0,06110029 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,03103265 0,06105033 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,03103265 0,06100045 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,03103265 0,06095065 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,03103265 0,06090094 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,03103265 0,0608513 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,03103265 0,06080175 ! protein homotetramerization GO:0051289 21 12 0,000 0,03103265 0,06075228 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,03103265 0,06070289 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,03103265 0,06065358 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,03103265 0,06060434 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,03103265 0,06055519 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,03103265 0,06050612 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,03103265 0,06045713 ! cranial nerve development GO:0021545 20 12 0,000 0,03103265 0,06040821 ! fucose catabolic process GO:0019317 22 12 0,000 0,03103265 0,06035938 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,03103265 0,06031062 ! histone methylation GO:0016571 26 12 0,000 0,03103265 0,06026195 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,03103265 0,06021335 ! autonomic nervous system development GO:0048483 24 12 0,000 0,03103265 0,06016483 ! gland morphogenesis GO:0022612 29 12 0,000 0,03103265 0,06011639 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,03103265 0,06006802 ! T cell homeostasis GO:0043029 25 12 0,000 0,03103265 0,06001974 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,03103265 0,05997153 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,03103265 0,0599234 ! spleen development GO:0048536 22 12 0,000 0,03103265 0,05987534 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,03103265 0,05982736 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,03103265 0,05977946 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,03103265 0,05973164 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,03103265 0,05968389 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,03103265 0,05963622 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 0,03103265 0,05958863 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,03103265 0,05954111 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,03103265 0,05949367 ! response to cold GO:0009409 17 12 0,000 0,03103265 0,0594463 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,03103265 0,05939901 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,03103265 0,05935179 ! cGMP metabolic process GO:0046068 18 13 0,000 0,03357536 0,06416388 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,03357536 0,06411295 ! regulation of chemokine production GO:0032642 18 13 0,000 0,03357536 0,06406211 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,03357536 0,06401135 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,03357536 0,06396067 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,03357536 0,06391007 ! lipid localization GO:0010876 28 13 0,000 0,03357536 0,06385954 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,03357536 0,0638091 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,03357536 0,06375874 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,03357536 0,06370846 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,03357536 0,06365825 ! endocrine pancreas development GO:0031018 22 13 0,000 0,03357536 0,06360813 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,03357536 0,06355808 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,03357536 0,06350811 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,03357536 0,06345823 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,03357536 0,06340842 ! methionine metabolic process GO:0006555 27 13 0,000 0,03357536 0,06335868 ! plasma membrane organization GO:0007009 24 13 0,000 0,03357536 0,06330903 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,03357536 0,06325945 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,03357536 0,06320995 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,03357536 0,06316053 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,03357536 0,06311119 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,03357536 0,06306192 ! response to X-ray GO:0010165 25 13 0,000 0,03357536 0,06301273 ! cytokine metabolic process GO:0042107 22 13 0,000 0,03357536 0,06296362 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,03357536 0,06291458 ! exocrine system development GO:0035272 32 13 0,000 0,03357536 0,06286562 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 0,03357536 0,06281674 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,03357536 0,06276793 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,03357536 0,06271919 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,03357536 0,06267054 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,03357536 0,06262196 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,03357536 0,06257345 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,03357536 0,06252502 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,03357536 0,06247666 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,03357536 0,06242838 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,03357536 0,06238017 ! regulation of cellular pH GO:0030641 22 13 0,000 0,03357536 0,06233204 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,03357536 0,06228398 ! ribosome assembly GO:0042255 17 13 0,000 0,03357536 0,062236 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,03357536 0,06218808 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,03357536 0,06214025 ! chromatin silencing GO:0006342 26 13 0,000 0,03357536 0,06209248 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,03357536 0,06204479 ! regulation of epidermis development GO:0045682 19 13 0,000 0,03357536 0,06199718 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,03357536 0,06194963 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,03357536 0,06190216 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,03357536 0,06185476 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,03357536 0,06180744 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,03357536 0,06176019 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,03357536 0,061713 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,03357536 0,06166589 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,03357536 0,06161886 ! embryonic placenta development GO:0001892 23 13 0,000 0,03357536 0,06157189 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,03357536 0,061525 ! insulin secretion GO:0030073 23 13 0,000 0,03357536 0,06147818 ! actin filament polymerization GO:0030041 24 13 0,000 0,03357536 0,06143142 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,03357536 0,06138474 ! acrosome reaction GO:0007340 18 13 0,000 0,03357536 0,06133813 ! rRNA transcription GO:0009303 25 14 0,000 0,03611149 0,06592128 ! lactation GO:0007595 26 14 0,000 0,03611149 0,0658713 ! tRNA modification GO:0006400 20 14 0,000 0,03611149 0,0658214 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,03611149 0,06577157 ! regulation of S phase GO:0033261 23 14 0,000 0,03611149 0,06572182 ! water transport GO:0006833 21 14 0,000 0,03611149 0,06567214 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,03611149 0,06562254 ! non-recombinational repair GO:0000726 25 14 0,000 0,03611149 0,06557301 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,03611149 0,06552356 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,03611149 0,06547418 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,03611149 0,06542488 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,03611149 0,06537565 ! RNA polyadenylation GO:0043631 30 14 0,000 0,03611149 0,0653265 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,03611149 0,06527742 ! palate development GO:0060021 31 14 0,000 0,03611149 0,06522841 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,03611149 0,06517948 ! regulated secretory pathway GO:0045055 23 14 0,000 0,03611149 0,06513062 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,03611149 0,06508183 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,03611149 0,06503312 ! arginine metabolic process GO:0006525 17 14 0,000 0,03611149 0,06498447 ! regulation of heart rate GO:0002027 24 14 0,000 0,03611149 0,06493591 ! organic alcohol transport GO:0015850 29 14 0,000 0,03611149 0,06488741 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,03611149 0,06483899 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,03611149 0,06479064 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,03611149 0,06474236 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,03611149 0,06469415 ! neutral amino acid transport GO:0015804 26 14 0,000 0,03611149 0,06464601 ! L-amino acid transport GO:0015807 30 14 0,000 0,03611149 0,06459795 ! bone mineralization GO:0030282 17 14 0,000 0,03611149 0,06454996 ! stem cell development GO:0048864 43 14 0,000 0,03611149 0,06450204 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,03611149 0,06445419 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,03611149 0,06440641 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,03611149 0,0643587 ! cerebellum development GO:0021549 21 14 0,000 0,03611149 0,06431106 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,03611149 0,06426349 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,03611149 0,064216 ! response to gamma radiation GO:0010332 28 14 0,000 0,03611149 0,06416857 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,03611149 0,06412121 ! cofactor transport GO:0051181 26 14 0,000 0,03611149 0,06407392 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,03611149 0,06402671 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,03611149 0,06397956 ! intestinal absorption GO:0050892 25 14 0,000 0,03611149 0,06393248 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,03611149 0,06388547 ! oxygen transport GO:0015671 21 14 0,000 0,03611149 0,06383853 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,03611149 0,06379166 ! male genitalia development GO:0030539 24 14 0,000 0,03611149 0,06374486 ! regulation of RNA stability GO:0043487 32 14 0,000 0,03611149 0,06369812 ! regulation of axon extension GO:0030516 37 14 0,000 0,03611149 0,06365146 ! release of cytochrome c from mitochondria GO:0001836 30 14 0,000 0,03611149 0,06360486 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,03611149 0,06355833 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,03864104 0,06796078 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,03864104 0,06791114 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,03864104 0,06786157 ! superoxide anion generation GO:0042554 20 15 0,000 0,03864104 0,06781207 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,03864104 0,06776265 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,03864104 0,06771329 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,03864104 0,06766401 ! copper ion transport GO:0006825 20 15 0,000 0,03864104 0,0676148 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,03864104 0,06756566 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,03864104 0,0675166 ! sulfate transport GO:0008272 23 15 0,000 0,03864104 0,0674676 ! response to cAMP GO:0051591 22 15 0,000 0,03864104 0,06741867 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,03864104 0,06736982 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,03864104 0,06732104 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,03864104 0,06727232 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,03864104 0,06722368 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,03864104 0,06717511 ! response to hexose stimulus GO:0009746 22 15 0,000 0,03864104 0,06712661 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,03864104 0,06707818 ! pituitary gland development GO:0021983 29 15 0,000 0,03864104 0,06702981 ! vesicle coating GO:0006901 33 15 0,000 0,03864104 0,06698152 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,03864104 0,0669333 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,03864104 0,06688514 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,03864104 0,06683706 ! regulation of exocytosis GO:0017157 22 15 0,000 0,03864104 0,06678905 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,03864104 0,0667411 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,03864104 0,06669322 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,03864104 0,06664541 ! regulation of vasodilation GO:0042312 26 15 0,000 0,03864104 0,06659767 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,03864104 0,06655 ! histone deacetylation GO:0016575 20 15 0,000 0,03864104 0,0665024 ! mRNA splice site selection GO:0006376 38 15 0,000 0,03864104 0,06645486 ! tissue regeneration GO:0042246 26 15 0,000 0,03864104 0,06640739 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,03864104 0,06635999 ! water homeostasis GO:0030104 27 15 0,000 0,03864104 0,06631266 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,03864104 0,0662654 ! muscle maintenance GO:0046716 26 15 0,000 0,03864104 0,0662182 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,03864104 0,06617107 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,03864104 0,06612401 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,03864104 0,06607701 ! dopamine metabolic process GO:0042417 35 15 0,000 0,03864104 0,06603008 ! heme biosynthetic process GO:0006783 29 15 0,000 0,03864104 0,06598322 ! cell killing GO:0001906 29 15 0,000 0,03864104 0,06593642 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,03864104 0,06588969 ! detection of bacterium GO:0016045 18 15 0,000 0,03864104 0,06584303 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,03864104 0,06579643 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,03864104 0,06574989 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,03864104 0,06570343 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,03864104 0,06565703 ! peptide hormone processing GO:0016486 23 15 0,000 0,03864104 0,06561069 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,04116404 0,06984534 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,04116404 0,06979612 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,04116404 0,06974696 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,04116404 0,06969788 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,04116404 0,06964887 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,04116404 0,06959992 ! bone remodeling GO:0046849 27 16 0,000 0,04116404 0,06955105 ! filopodium assembly GO:0046847 32 16 0,000 0,04116404 0,06950224 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,04116404 0,0694535 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,04116404 0,06940483 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,04116404 0,06935623 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,04116404 0,06930769 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,04116404 0,06925922 ! startle response GO:0001964 28 16 0,000 0,04116404 0,06921082 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,04116404 0,06916249 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,04116404 0,06911423 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,04116404 0,06906603 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,04116404 0,0690179 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,04116404 0,06896984 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,04116404 0,06892184 ! protein polyubiquitination GO:0000209 34 16 0,000 0,04116404 0,06887392 ! glutamate metabolic process GO:0006536 22 16 0,000 0,04116404 0,06882605 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,04116404 0,06877826 ! response to osmotic stress GO:0006970 25 16 0,000 0,04116404 0,06873053 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,04116404 0,06868286 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,04116404 0,06863527 ! fructose metabolic process GO:0006000 25 16 0,000 0,04116404 0,06858774 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,04116404 0,06854027 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,04116404 0,06849287 ! intermediate filament-based process GO:0045103 32 16 0,000 0,04116404 0,06844554 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,04116404 0,06839827 ! negative regulation of immune response GO:0050777 35 16 0,000 0,04116404 0,06835106 ! axon cargo transport GO:0008088 43 16 0,000 0,04116404 0,06830392 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,04116404 0,06825685 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,04116404 0,06820984 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 0,04116404 0,0681629 ! DNA replication initiation GO:0006270 27 16 0,000 0,04116404 0,06811602 ! neuron recognition GO:0008038 35 16 0,000 0,04116404 0,0680692 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,04116404 0,06802245 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,04116404 0,06797577 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,04116404 0,06792914 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,04116404 0,06788258 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,04116404 0,06783609 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,04116404 0,06778966 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,04116404 0,06774329 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,04116404 0,06769699 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,04116404 0,06765074 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,04116404 0,06760457 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,04116404 0,06755845 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 0,04116404 0,0675124 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,04116404 0,06746641 ! defense response to virus GO:0051607 37 16 0,000 0,04116404 0,06742048 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,04368051 0,0714934 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,04368051 0,0714448 ! metencephalon development GO:0022037 30 17 0,000 0,04368051 0,07139626 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,04368051 0,07134779 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,04368051 0,07129939 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,04368051 0,07125105 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,04368051 0,07120278 ! signal complex assembly GO:0007172 41 17 0,000 0,04368051 0,07115457 ! gene silencing by RNA GO:0031047 36 17 0,000 0,04368051 0,07110643 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,04368051 0,07105835 ! glial cell development GO:0021782 27 17 0,000 0,04368051 0,07101034 ! limbic system development GO:0021761 36 17 0,000 0,04368051 0,07096239 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,04368051 0,07091451 ! adult walking behavior GO:0007628 33 17 0,000 0,04368051 0,07086669 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,04368051 0,07081893 ! heart looping GO:0001947 30 17 0,000 0,04368051 0,07077125 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,04368051 0,07072362 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,04368051 0,07067606 ! myoblast differentiation GO:0045445 45 17 0,000 0,04368051 0,07062856 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,04368051 0,07058113 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,04368051 0,07053376 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,04368051 0,07048645 ! glycine metabolic process GO:0006544 28 17 0,000 0,04368051 0,07043921 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,04368051 0,07039203 ! NAD metabolic process GO:0019674 29 17 0,000 0,04368051 0,07034491 ! membrane budding GO:0006900 37 17 0,000 0,04368051 0,07029786 ! DNA integration GO:0015074 29 17 0,000 0,04368051 0,07025087 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,04368051 0,07020394 ! regulation of protein binding GO:0043393 33 17 0,000 0,04368051 0,07015708 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,04368051 0,07011027 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,04368051 0,07006353 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,04368051 0,07001685 ! genitalia development GO:0048806 30 17 0,000 0,04368051 0,06997024 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,04368051 0,06992369 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,04368051 0,06987719 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,04368051 0,06983076 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,04368051 0,0697844 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,04368051 0,06973809 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,04368051 0,06969184 ! steroid catabolic process GO:0006706 31 17 0,000 0,04368051 0,06964566 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,04368051 0,06959954 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,04368051 0,06955347 ! gas transport GO:0015669 25 17 0,000 0,04368051 0,06950747 ! organic cation transport GO:0015695 31 17 0,000 0,04368051 0,06946153 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,04368051 0,06941565 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,04368051 0,06936983 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,04368051 0,06932408 ! microspike assembly GO:0030035 36 17 0,000 0,04368051 0,06927838 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,04368051 0,06923274 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,04368051 0,06918716 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,04619045 0,07311462 ! neuron maturation GO:0042551 42 18 0,000 0,04619045 0,07306655 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,04619045 0,07301854 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,04619045 0,0729706 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,04619045 0,07292272 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,04619045 0,0728749 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,04619045 0,07282714 ! memory GO:0007613 31 18 0,000 0,04619045 0,07277945 ! negative regulation of ion transport GO:0043271 24 18 0,000 0,04619045 0,07273182 ! patterning of blood vessels GO:0001569 39 18 0,000 0,04619045 0,07268425 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,04619045 0,07263674 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,04619045 0,0725893 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,04619045 0,07254192 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,04619045 0,0724946 ! glutamine metabolic process GO:0006541 29 18 0,000 0,04619045 0,07244734 ! response to retinoic acid GO:0032526 26 18 0,000 0,04619045 0,07240014 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,04619045 0,07235301 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,04619045 0,07230593 ! response to fungus GO:0009620 21 18 0,000 0,04619045 0,07225892 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,04619045 0,07221197 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,04619045 0,07216508 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,04619045 0,07211825 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,04619045 0,07207148 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,04619045 0,07202477 ! vitamin transport GO:0051180 27 18 0,000 0,04619045 0,07197812 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,04619045 0,07193153 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,04619045 0,07188501 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,04619045 0,07183854 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,04619045 0,07179213 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,04619045 0,07174578 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,04619045 0,0716995 ! nerve development GO:0021675 28 18 0,000 0,04619045 0,07165327 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,04619045 0,0716071 ! protein secretion GO:0009306 39 19 0,000 0,04869389 0,07543946 ! positive regulation of translation GO:0045727 30 19 0,000 0,04869389 0,07539092 ! negative regulation of defense response GO:0031348 25 19 0,000 0,04869389 0,07534244 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,04869389 0,07529402 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,04869389 0,07524566 ! skin development GO:0043588 36 19 0,000 0,04869389 0,07519736 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,04869389 0,07514913 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,04869389 0,07510095 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,04869389 0,07505284 ! bile acid metabolic process GO:0008206 29 19 0,000 0,04869389 0,07500479 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,04869389 0,07495681 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,04869389 0,07490888 ! cerebral cortex development GO:0021987 36 19 0,000 0,04869389 0,07486101 ! pigmentation during development GO:0048066 41 19 0,000 0,04869389 0,07481321 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,04869389 0,07476547 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,04869389 0,07471779 ! heme metabolic process GO:0042168 36 19 0,000 0,04869389 0,07467016 ! actin filament bundle formation GO:0051017 42 19 0,000 0,04869389 0,0746226 ! neuromuscular junction development GO:0007528 34 19 0,000 0,04869389 0,0745751 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,04869389 0,07452766 ! plasma membrane fusion GO:0045026 28 19 0,000 0,04869389 0,07448029 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,04869389 0,07443297 ! peptide cross-linking GO:0018149 37 19 0,000 0,04869389 0,07438571 ! protein export from nucleus GO:0006611 36 19 0,000 0,04869389 0,07433851 ! heart process GO:0003015 30 19 0,000 0,04869389 0,07429137 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,04869389 0,07424429 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,04869389 0,07419727 ! visual learning GO:0008542 36 19 0,000 0,04869389 0,07415031 ! cellular pigmentation GO:0033059 36 19 0,000 0,04869389 0,07410341 ! G1 phase GO:0051318 40 19 0,000 0,04869389 0,07405657 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,04869389 0,07400978 ! cell-cell junction organization GO:0045216 35 19 0,000 0,04869389 0,07396306 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,04869389 0,0739164 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,04869389 0,07386979 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,04869389 0,07382324 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,04869389 0,07377676 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,04869389 0,07373033 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,04869389 0,07368395 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,04869389 0,07363764 ! cilium assembly GO:0042384 37 19 0,000 0,04869389 0,07359139 ! peptide hormone secretion GO:0030072 31 19 0,000 0,04869389 0,07354519 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,05119083 0,07726797 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,05119083 0,07721953 ! positive regulation of ossification GO:0045778 47 20 0,000 0,05119083 0,07717115 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,05119083 0,07712282 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,05119083 0,07707456 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 0,000 0,05119083 0,07702636 ! cAMP metabolic process GO:0046058 36 20 0,000 0,05119083 0,07697822 ! response to vitamin GO:0033273 31 20 0,000 0,05119083 0,07693014 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,05119083 0,07688212 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 0,05119083 0,07683415 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,05119083 0,07678625 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,05119083 0,07673841 ! response to alkaloid GO:0043279 38 20 0,000 0,05119083 0,07669063 ! retinoid metabolic process GO:0001523 32 20 0,000 0,05119083 0,07664291 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,05119083 0,07659524 ! apoptotic mitochondrial changes GO:0008637 41 20 0,000 0,05119083 0,07654764 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,05119083 0,07650009 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,05119083 0,07645261 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,05119083 0,07640518 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 0,000 0,05119083 0,07635781 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,05119083 0,0763105 ! body fluid secretion GO:0007589 31 20 0,000 0,05119083 0,07626325 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,05119083 0,07621606 ! peptide secretion GO:0002790 35 20 0,000 0,05119083 0,07616892 ! stem cell differentiation GO:0048863 53 20 0,000 0,05119083 0,07612185 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,05119083 0,07607483 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,05119083 0,07602787 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,05119083 0,07598097 ! sensory perception of pain GO:0019233 30 20 0,000 0,05119083 0,07593412 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,05119083 0,07588734 ! diencephalon development GO:0021536 34 20 0,000 0,05119083 0,07584061 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,05119083 0,07579394 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,05119083 0,07574732 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,05119083 0,07570077 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,05119083 0,07565427 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,05119083 0,07560783 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,05119083 0,07556144 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,05119083 0,07551511 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,05119083 0,07546884 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,05119083 0,07542263 ! regulation of glucose import GO:0046324 29 20 0,000 0,05119083 0,07537647 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,05119083 0,07533037 ! actin filament-based movement GO:0030048 43 20 0,000 0,05119083 0,07528432 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,05119083 0,07523833 ! negative regulation of T cell activation GO:0050868 40 20 0,000 0,05119083 0,0751924 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,05119083 0,07514652 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,05119083 0,0751007 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,05119083 0,07505494 ! regulation of cell killing GO:0031341 42 21 0,000 0,05368131 0,07865849 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,05368131 0,07861061 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,05368131 0,0785628 ! hormone secretion GO:0046879 38 21 0,000 0,05368131 0,07851504 ! glycerol metabolic process GO:0006071 34 21 0,000 0,05368131 0,07846734 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,05368131 0,0784197 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,05368131 0,07837211 ! axis specification GO:0009798 38 21 0,000 0,05368131 0,07832458 ! ovarian follicle development GO:0001541 35 21 0,000 0,05368131 0,07827711 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,05368131 0,0782297 ! smooth muscle contraction GO:0006939 46 21 0,000 0,05368131 0,07818235 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,05368131 0,07813505 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,05368131 0,07808781 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,05368131 0,07804063 ! cell aging GO:0007569 44 21 0,000 0,05368131 0,0779935 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,05368131 0,07794643 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,05368131 0,07789942 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,05368131 0,07785246 ! cytolysis GO:0019835 24 21 0,000 0,05368131 0,07780557 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,05368131 0,07775872 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,05368131 0,07771194 ! oogenesis GO:0048477 36 21 0,000 0,05368131 0,07766521 ! DNA modification GO:0006304 34 21 0,000 0,05368131 0,07761853 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,05368131 0,07757192 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,05368131 0,07752535 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,05368131 0,07747885 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,05368131 0,0774324 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,05368131 0,077386 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,05368131 0,07733966 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,05368131 0,07729338 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,05368131 0,07724715 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,05368131 0,07720098 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,05368131 0,07715486 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,05368131 0,0771088 ! collagen catabolic process GO:0030574 28 21 0,000 0,05368131 0,07706279 ! sperm-egg recognition GO:0035036 21 21 0,000 0,05368131 0,07701684 ! gut development GO:0048565 39 21 0,000 0,05368131 0,07697094 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,05616534 0,08048469 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,05616534 0,08043679 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,05616534 0,08038894 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,05616534 0,08034114 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,05616534 0,0802934 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,05616534 0,08024572 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,05616534 0,0801981 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,05616534 0,08015053 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,05616534 0,08010302 ! regeneration GO:0031099 41 22 0,000 0,05616534 0,08005557 ! keratinization GO:0031424 28 22 0,000 0,05616534 0,08000817 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,05616534 0,07996083 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,05616534 0,07991354 ! sensory perception of taste GO:0050909 28 22 0,000 0,05616534 0,07986631 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,05616534 0,07981914 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,05616534 0,07977202 ! vacuolar transport GO:0007034 36 22 0,000 0,05616534 0,07972496 ! lysosome organization GO:0007040 41 22 0,000 0,05616534 0,07967795 ! central nervous system neuron development GO:0021954 46 22 0,000 0,05616534 0,079631 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,05616534 0,0795841 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,05616534 0,07953726 ! fucose metabolic process GO:0006004 39 22 0,000 0,05616534 0,07949047 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,05616534 0,07944374 ! ureteric bud development GO:0001657 43 22 0,000 0,05616534 0,07939706 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,05616534 0,07935044 GO:0060415|muscle tissue morphogenesis, ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,05616534 0,07930387 ! positive regulation of intracellular transport GO:0032388 37 22 0,000 0,05616534 0,07925736 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,05616534 0,0792109 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,05616534 0,0791645 ! sarcomere organization GO:0045214 30 22 0,000 0,05616534 0,07911815 ! positive regulation of B cell activation GO:0050871 38 22 0,000 0,05616534 0,07907186 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,05616534 0,07902561 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,05616534 0,07897943 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,05616534 0,07893329 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,05616534 0,07888722 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,05616534 0,07884119 ! protein stabilization GO:0050821 39 22 0,000 0,05616534 0,07879522 ! positive regulation of DNA replication GO:0045740 43 23 0,000 0,05864292 0,08222312 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,05864292 0,08217523 ! positive regulation of cell adhesion GO:0045785 56 23 0,000 0,05864292 0,0821274 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,05864292 0,08207962 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,05864292 0,0820319 ! gluconeogenesis GO:0006094 33 23 0,000 0,05864292 0,08198424 ! viral genome replication GO:0019079 41 23 0,000 0,05864292 0,08193663 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,05864292 0,08188907 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,05864292 0,08184157 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,05864292 0,08179413 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,05864292 0,08174674 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,05864292 0,0816994 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,05864292 0,08165212 ! visual behavior GO:0007632 42 23 0,000 0,05864292 0,0816049 ! regulation of DNA recombination GO:0000018 48 23 0,000 0,05864292 0,08155773 ! response to ethanol GO:0045471 46 23 0,000 0,05864292 0,08151061 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,05864292 0,08146355 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,05864292 0,08141654 ! peroxisome organization GO:0007031 37 23 0,000 0,05864292 0,08136959 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,05864292 0,08132269 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,05864292 0,08127585 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,05864292 0,08122906 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,05864292 0,08118232 GO:0051693|actin filament capping, ! sex determination GO:0007530 47 23 0,000 0,05864292 0,08113564 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,05864292 0,08108901 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,05864292 0,08104243 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,05864292 0,08099591 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,05864292 0,08094944 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,05864292 0,08090302 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,05864292 0,08085666 ! fatty acid transport GO:0015908 44 23 0,000 0,05864292 0,08081035 ! platelet activation GO:0030168 37 23 0,000 0,05864292 0,08076409 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,05864292 0,08071789 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,05864292 0,08067174 ! hormone transport GO:0009914 40 23 0,000 0,05864292 0,08062564 ! cell-cell recognition GO:0009988 25 23 0,000 0,05864292 0,0805796 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,05864292 0,0805336 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,05864292 0,08048766 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,05864292 0,08044177 ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,05864292 0,08039594 ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,06111409 0,08373604 ! positive regulation of fibroblast proliferation GO:0048146 43 24 0,000 0,06111409 0,08368838 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,06111409 0,08364078 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,06111409 0,08359323 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,06111409 0,08354573 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,06111409 0,08349829 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,06111409 0,0834509 ! spinal cord development GO:0021510 47 24 0,000 0,06111409 0,08340357 ! vacuole organization GO:0007033 43 24 0,000 0,06111409 0,08335629 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,06111409 0,08330906 ! digestive system process GO:0022600 39 24 0,000 0,06111409 0,08326189 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,06111409 0,08321477 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,06111409 0,0831677 ! regulation of behavior GO:0050795 43 24 0,000 0,06111409 0,08312068 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,06111409 0,08307372 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,06111409 0,08302682 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,06111409 0,08297996 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 47 24 0,000 0,06111409 0,08293316 ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,06111409 0,08288641 ! membrane depolarization GO:0051899 39 24 0,000 0,06111409 0,08283971 ! pallium development GO:0021543 49 24 0,000 0,06111409 0,08279307 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,06111409 0,08274648 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,06111409 0,08269994 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,06111409 0,08265345 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,06111409 0,08260702 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,06111409 0,08256064 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,06111409 0,08251431 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,06111409 0,08246803 ! regulation of amine transport GO:0051952 40 24 0,000 0,06111409 0,0824218 ! protein tetramerization GO:0051262 52 24 0,000 0,06111409 0,08237563 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,06357885 0,08564989 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 0,000 0,06357885 0,08560196 ! myelination GO:0042552 45 25 0,000 0,06357885 0,08555408 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,06357885 0,08550626 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,06357885 0,08545849 ! phototransduction GO:0007602 33 25 0,000 0,06357885 0,08541078 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,06357885 0,08536311 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 0,000 0,06357885 0,08531551 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 0,000 0,06357885 0,08526795 ! sperm motility GO:0030317 31 25 0,000 0,06357885 0,08522045 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,06357885 0,085173 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,06357885 0,0851256 ! receptor metabolic process GO:0043112 46 25 0,000 0,06357885 0,08507825 ! chromosome condensation GO:0030261 45 25 0,000 0,06357885 0,08503096 ! response to starvation GO:0042594 42 25 0,000 0,06357885 0,08498372 ! osteoblast differentiation GO:0001649 60 25 0,000 0,06357885 0,08493654 ! response to endoplasmic reticulum stress GO:0034976 43 25 0,000 0,06357885 0,0848894 ! neural crest cell development GO:0014032 54 25 0,000 0,06357885 0,08484232 GO:0014033|neural crest cell differentiation, ! negative regulation of cell development GO:0010721 73 25 0,000 0,06357885 0,08479529 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,06357885 0,08474831 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,06357885 0,08470139 ! interaction with host GO:0051701 62 25 0,000 0,06357885 0,08465451 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,06357885 0,08460769 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,06357885 0,08456092 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! immunoglobulin production GO:0002377 55 25 0,000 0,06357885 0,0845142 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,06357885 0,08446753 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,06357885 0,08442092 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,06357885 0,08437435 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,06357885 0,08432784 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,06357885 0,08428138 ! telomere organization GO:0032200 43 25 0,000 0,06357885 0,08423497 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,06357885 0,08418861 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,06357885 0,0841423 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,06603722 0,08734774 ! embryonic pattern specification GO:0009880 44 26 0,000 0,06603722 0,08729975 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,06603722 0,08725181 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,06603722 0,08720392 ! initiation of viral infection GO:0019059 57 26 0,000 0,06603722 0,08715608 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,06603722 0,0871083 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,06603722 0,08706057 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,06603722 0,08701289 ! molting cycle process GO:0022404 50 26 0,000 0,06603722 0,08696527 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,06603722 0,08691769 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,06603722 0,08687017 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,06603722 0,0868227 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,06603722 0,08677528 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,06603722 0,08672791 GO:0051297|centrosome organization, ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,06603722 0,0866806 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 0,000 0,06603722 0,08663334 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 0,000 0,06603722 0,08658613 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,06603722 0,08653896 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,06603722 0,08649186 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,06603722 0,0864448 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,06603722 0,08639779 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,06603722 0,08635084 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,06603722 0,08630393 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,06603722 0,08625708 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,06603722 0,08621028 ! blastocyst development GO:0001824 49 26 0,000 0,06603722 0,08616352 ! leukocyte proliferation GO:0070661 52 26 0,000 0,06603722 0,08611682 GO:0032943|mononuclear cell proliferation, ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,06603722 0,08607017 ! regulation of fibroblast proliferation GO:0048145 52 27 0,000 0,06848921 0,08921768 ! neuron fate commitment GO:0048663 48 27 0,000 0,06848921 0,0891694 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,06848921 0,08912117 ! iron ion transport GO:0006826 59 27 0,000 0,06848921 0,089073 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,06848921 0,08902488 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,06848921 0,08897681 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,06848921 0,08892879 ! fat cell differentiation GO:0045444 50 27 0,000 0,06848921 0,08888082 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,06848921 0,08883291 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,06848921 0,08878505 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,06848921 0,08873724 ! autophagy GO:0006914 41 27 0,000 0,06848921 0,08868948 ! male gonad development GO:0008584 44 27 0,000 0,06848921 0,08864177 ! response to toxin GO:0009636 47 27 0,000 0,06848921 0,08859411 ! primary neural tube formation GO:0014020 51 27 0,000 0,06848921 0,08854651 ! base-excision repair GO:0006284 41 27 0,000 0,06848921 0,08849895 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,06848921 0,08845145 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,06848921 0,08840399 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,06848921 0,08835659 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,06848921 0,08830924 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,06848921 0,08826194 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,06848921 0,08821469 ! negative regulation of lymphocyte activation GO:0051250 53 27 0,000 0,06848921 0,08816749 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,07093485 0,09126698 ! circadian rhythm GO:0007623 50 28 0,000 0,07093485 0,0912182 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,07093485 0,09116948 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,07093485 0,0911208 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,07093485 0,09107218 ! ER-nuclear signaling pathway GO:0006984 48 28 0,000 0,07093485 0,09102361 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,07093485 0,09097508 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,07093485 0,09092662 ! synaptogenesis GO:0007416 42 28 0,000 0,07093485 0,0908782 ! peptidyl-tyrosine modification GO:0018212 50 28 0,000 0,07093485 0,09082983 ! lipid oxidation GO:0034440 43 28 0,000 0,07093485 0,09078152 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,07093485 0,09073326 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,07093485 0,09068505 ! translational initiation GO:0006413 65 29 0,000 0,07337416 0,0937537 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,07337416 0,09370394 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,07337416 0,09365423 ! regulation of pH GO:0006885 43 29 0,000 0,07337416 0,09360457 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,07337416 0,09355497 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,07337416 0,09350541 ! catechol metabolic process GO:0009712 54 29 0,000 0,07337416 0,09345591 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,07337416 0,09340647 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,07337416 0,09335707 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,07337416 0,09330773 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,07337416 0,09325844 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,07337416 0,0932092 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,07337416 0,09316001 ! cell fate determination GO:0001709 60 29 0,000 0,07337416 0,09311088 ! detection of light stimulus GO:0009583 38 29 0,000 0,07337416 0,09306179 ! cellular response to extracellular stimulus GO:0031668 48 29 0,000 0,07337416 0,09301276 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,07337416 0,09296378 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,07337416 0,09291485 ! tissue homeostasis GO:0001894 48 29 0,000 0,07337416 0,09286598 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,07337416 0,09281715 ! phenol metabolic process GO:0018958 55 30 0,000 0,07580713 0,09584444 ! zinc ion transport GO:0006829 45 30 0,000 0,07580713 0,0957941 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,07580713 0,09574381 ! cell junction assembly GO:0034329 78 30 0,000 0,07580713 0,09569358 ! regulation of innate immune response GO:0045088 51 30 0,000 0,07580713 0,0956434 ! acute-phase response GO:0006953 49 30 0,000 0,07580713 0,09559327 ! myofibril assembly GO:0030239 47 30 0,000 0,07580713 0,0955432 GO:0055002|striated muscle cell development, ! determination of left/right symmetry GO:0007368 47 30 0,000 0,07580713 0,09549317 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,07580713 0,0954432 ! phospholipid transport GO:0015914 51 30 0,000 0,07580713 0,09539329 ! ensheathment of neurons GO:0007272 57 30 0,000 0,07580713 0,09534342 GO:0008366|axon ensheathment, ! negative regulation of leukocyte activation GO:0002695 56 30 0,000 0,07580713 0,09529361 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,07580713 0,09524385 ! eye morphogenesis GO:0048592 60 30 0,000 0,07580713 0,09519414 ! regulation of B cell activation GO:0050864 50 30 0,000 0,07580713 0,09514448 ! response to heat GO:0009408 50 30 0,000 0,07580713 0,09509487 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,0782338 0,09808782 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,0782338 0,09803674 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,0782338 0,0979857 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,0782338 0,09793472 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,0782338 0,09788379 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,0782338 0,09783292 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,0782338 0,0977821 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,0782338 0,09773133 ! ovulation cycle process GO:0022602 49 31 0,000 0,0782338 0,09768061 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,0782338 0,09762994 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,0782338 0,09757933 ! peptide transport GO:0015833 55 31 0,000 0,0782338 0,09752877 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,0782338 0,09747827 ! iron ion homeostasis GO:0055072 54 31 0,000 0,0782338 0,09742781 ! mesoderm formation GO:0001707 69 31 0,000 0,0782338 0,09737741 ! natural killer cell activation GO:0030101 45 31 0,000 0,0782338 0,09732706 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,0782338 0,09727676 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,0782338 0,09722652 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,0782338 0,09717632 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,0782338 0,09712618 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,0782338 0,09707609 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,08065418 0,10002782 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,08065418 0,09997628 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,08065418 0,0999248 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,08065418 0,09987337 ! cholesterol transport GO:0030301 56 32 0,000 0,08065418 0,099822 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,08065418 0,09977068 ! spliceosome assembly GO:0000245 67 32 0,000 0,08065418 0,09971941 ! spindle organization GO:0007051 46 32 0,000 0,08065418 0,09966819 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,08065418 0,09961703 ! metanephros development GO:0001656 74 32 0,000 0,08065418 0,09956591 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,08065418 0,09951485 ! response to ionizing radiation GO:0010212 65 32 0,000 0,08065418 0,09946385 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,08065418 0,09941289 ! regulation of protein import into nucleus GO:0042306 63 32 0,000 0,08065418 0,09936199 ! muscle cell development GO:0055001 49 32 0,000 0,08065418 0,09931114 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,08065418 0,09926034 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,08065418 0,09920959 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,08065418 0,0991589 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,08065418 0,09910826 ! ovulation cycle GO:0042698 51 32 0,000 0,08065418 0,09905767 ! peripheral nervous system development GO:0007422 64 32 0,000 0,08065418 0,09900713 ! BMP signaling pathway GO:0030509 64 32 0,000 0,08065418 0,09895664 ! hindbrain development GO:0030902 61 32 0,000 0,08065418 0,0989062 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,08065418 0,09885582 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,08065418 0,09880548 ! positive regulation of catabolic process GO:0009896 64 32 0,000 0,08065418 0,0987552 ! gene silencing GO:0016458 65 32 0,000 0,08065418 0,09870497 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,08306829 0,10160768 ! post-embryonic development GO:0009791 69 33 0,000 0,08306829 0,10155605 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,08306829 0,10150447 ! protein targeting to membrane GO:0006612 68 33 0,000 0,08306829 0,10145294 ! ceramide metabolic process GO:0006672 64 33 0,000 0,08306829 0,10140147 ! formation of primary germ layer GO:0001704 72 33 0,000 0,08306829 0,10135005 ! cell fate specification GO:0001708 52 33 0,000 0,08306829 0,10129868 ! sterol transport GO:0015918 57 33 0,000 0,08306829 0,10124737 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,08306829 0,1011961 GO:0060326|cell chemotaxis, ! adult locomotory behavior GO:0008344 59 33 0,000 0,08306829 0,10114489 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,08306829 0,10109373 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,08306829 0,10104262 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,08547613 0,10391894 ! glial cell differentiation GO:0010001 63 34 0,000 0,08547613 0,10386645 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,08547613 0,10381402 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,08547613 0,10376164 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,08547613 0,10370932 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,08547613 0,10365704 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,08547613 0,10360482 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,08547613 0,10355266 ! mismatch repair GO:0006298 46 34 0,000 0,08547613 0,10350054 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,08547613 0,10344848 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,08547613 0,10339647 ! placenta development GO:0001890 53 34 0,000 0,08547613 0,10334451 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 0,000 0,08547613 0,1032926 ! regulation of muscle development GO:0048634 70 35 0,000 0,08787773 0,10614148 ! negative regulation of secretion GO:0051048 63 35 0,000 0,08787773 0,10608822 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,08787773 0,10603502 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,08787773 0,10598187 ! odontogenesis GO:0042476 66 35 0,000 0,08787773 0,10592877 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,08787773 0,10587573 ! female gonad development GO:0008585 58 35 0,000 0,08787773 0,10582274 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,08787773 0,1057698 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,08787773 0,10571691 ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 0,08787773 0,10566408 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,08787773 0,1056113 ! neural tube formation GO:0001841 67 35 0,000 0,08787773 0,10555858 ! vesicle localization GO:0051648 64 35 0,000 0,08787773 0,1055059 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,09027311 0,10832773 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,09027311 0,10827373 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,09027311 0,10821978 ! cell junction organization GO:0034330 86 36 0,000 0,09027311 0,10816589 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,09027311 0,10811205 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,09027311 0,10805826 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,09027311 0,10800453 ! regulation of proteolysis GO:0030162 72 36 0,000 0,09027311 0,10795084 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,09027311 0,10789722 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,09027311 0,10784364 ! embryonic organ development GO:0048568 57 36 0,000 0,09027311 0,10779012 ! negative regulation of cell activation GO:0050866 65 36 0,000 0,09027311 0,10773666 ! RNA export from nucleus GO:0006405 56 37 0,000 0,09266227 0,11053318 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,09266227 0,11047841 ! meiosis I GO:0007127 65 37 0,000 0,09266227 0,11042369 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,09266227 0,11036902 ! sister chromatid segregation GO:0000819 58 37 0,000 0,09266227 0,11031441 ! actomyosin structure organization GO:0031032 62 37 0,000 0,09266227 0,11025986 ! organic anion transport GO:0015711 68 37 0,000 0,09266227 0,11020535 ! tissue remodeling GO:0048771 76 37 0,000 0,09266227 0,1101509 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,09266227 0,11009651 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,09266227 0,11004217 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,09266227 0,10998788 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,09266227 0,10993364 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,09266227 0,10987946 GO:0015986|ATP synthesis coupled proton transport, ! glycogen metabolic process GO:0005977 61 37 0,000 0,09266227 0,10982533 ! pigment metabolic process GO:0042440 80 37 0,000 0,09266227 0,10977126 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,09504524 0,1125388 GO:0006956|complement activation, ! positive regulation of DNA metabolic process GO:0051054 72 38 0,000 0,09504524 0,11248345 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,09504524 0,11242815 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,09504524 0,1123729 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,09504524 0,11231771 ! carbohydrate homeostasis GO:0033500 53 38 0,000 0,09504524 0,11226257 GO:0042593|glucose homeostasis, ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,09504524 0,11220748 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 0,000 0,09504524 0,11215245 ! lipid homeostasis GO:0055088 67 38 0,000 0,09504524 0,11209747 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,09504524 0,11204255 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,09504524 0,11198768 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,09504524 0,11193287 ! positive regulation of leukocyte proliferation GO:0070665 62 38 0,000 0,09504524 0,11187811 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! glucan metabolic process GO:0044042 62 38 0,000 0,09504524 0,1118234 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,09742203 0,11456374 ! mammary gland development GO:0030879 86 39 0,000 0,09742203 0,11450777 ! learning GO:0007612 77 39 0,000 0,09742203 0,11445186 ! ear morphogenesis GO:0042471 60 39 0,000 0,09742203 0,114396 ! organic ether metabolic process GO:0018904 55 39 0,000 0,09742203 0,1143402 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,09742203 0,11428445 ! ion transmembrane transport GO:0034220 66 39 0,000 0,09742203 0,11422875 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,09742203 0,11417311 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,09742203 0,11411753 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,09742203 0,114062 ! RNA modification GO:0009451 57 39 0,000 0,09742203 0,11400652 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,09742203 0,11395109 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,09979265 0,11666721 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,09979265 0,11661055 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,09979265 0,11655394 ! feeding behavior GO:0007631 59 40 0,000 0,09979265 0,11649739 ! negative regulation of binding GO:0051100 72 40 0,000 0,09979265 0,1164409 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,09979265 0,11638445 ! mesenchymal cell development GO:0014031 87 40 0,000 0,09979265 0,11632806 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,09979265 0,11627173 ! maintenance of protein location GO:0045185 91 40 0,000 0,09979265 0,11621545 ! cytokinesis GO:0000910 72 40 0,000 0,09979265 0,11615923 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,10215713 0,11885399 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,10215713 0,11879655 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,10215713 0,11873916 ! gliogenesis GO:0042063 88 41 0,000 0,10215713 0,11868182 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,10215713 0,11862455 ! regulation of T cell proliferation GO:0042129 71 41 0,000 0,10215713 0,11856732 ! T cell differentiation GO:0030217 81 41 0,000 0,10215713 0,11851015 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,10215713 0,11845304 ! regulation of T cell differentiation GO:0045580 70 41 0,000 0,10215713 0,11839598 ! female gamete generation GO:0007292 61 41 0,000 0,10215713 0,11833898 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,10215713 0,11828203 ! response to reactive oxygen species GO:0000302 67 42 0,000 0,10451548 0,12095442 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,10451548 0,12089627 ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,10451548 0,12083817 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,10451548 0,12078013 ! regulation of intracellular protein transport GO:0033157 80 42 0,000 0,10451548 0,12072215 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,10451548 0,12066422 ! neuron migration GO:0001764 79 42 0,000 0,10451548 0,12060635 ! regulation of protein secretion GO:0050708 71 42 0,000 0,10451548 0,12054853 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,10451548 0,12049077 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,10686771 0,12314353 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,10686771 0,12308459 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,10686771 0,12302569 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,10686771 0,12296686 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,10686771 0,12290808 ! glucose transport GO:0015758 65 43 0,000 0,10686771 0,12284935 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,10686771 0,12279069 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,10686771 0,12273208 ! neural tube development GO:0021915 77 43 0,000 0,10686771 0,12267352 ! striated muscle contraction GO:0006941 77 43 0,000 0,10686771 0,12261502 ! phagocytosis GO:0006909 90 43 0,000 0,10686771 0,12255658 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,10686771 0,12249819 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,10921383 0,12512785 ! hexose transport GO:0008645 67 44 0,000 0,10921383 0,12506829 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,10921383 0,12500879 ! male sex differentiation GO:0046661 76 44 0,000 0,10921383 0,12494935 ! double-strand break repair GO:0006302 81 44 0,000 0,10921383 0,12488996 ! biopolymer methylation GO:0043414 84 44 0,000 0,10921383 0,12483063 ! B cell differentiation GO:0030183 107 44 0,000 0,10921383 0,12477136 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,10921383 0,12471214 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,10921383 0,12465298 ! developmental growth GO:0048589 82 44 0,000 0,10921383 0,12459387 ! maintenance of location in cell GO:0051651 97 44 0,000 0,10921383 0,12453483 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,11155388 0,12714288 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,11155388 0,12708268 ! leukocyte migration GO:0050900 68 45 0,000 0,11155388 0,12702254 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,11155388 0,12696245 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,11155388 0,12690242 ! induction of apoptosis by intracellular signals GO:0008629 93 45 0,000 0,11155388 0,12684245 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,11155388 0,12678253 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,11155388 0,12672267 ! icosanoid metabolic process GO:0006690 80 45 0,000 0,11155388 0,12666287 ! cell growth GO:0016049 84 45 0,000 0,11155388 0,12660313 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,11388785 0,12919103 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 0,000 0,11388785 0,12913014 ! regulation of gene-specific transcription GO:0032583 96 46 0,000 0,11388785 0,12906932 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,11388785 0,12900855 ! pigmentation GO:0043473 100 46 0,000 0,11388785 0,12894784 ! positive regulation of protein transport GO:0051222 72 46 0,000 0,11388785 0,12888719 ! positive regulation of defense response GO:0031349 76 47 0,000 0,11621577 0,13145987 ! response to calcium ion GO:0051592 81 47 0,000 0,11621577 0,13139809 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,11621577 0,13133637 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,11621577 0,13127471 ! JNK cascade GO:0007254 91 47 0,000 0,11621577 0,13121311 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,11621577 0,13115157 ! methylation GO:0032259 90 47 0,000 0,11621577 0,13109008 ! protein homooligomerization GO:0051260 76 47 0,000 0,11621577 0,13102865 ! mitochondrial transport GO:0006839 82 48 0,000 0,11853765 0,13358388 ! cellular component disassembly GO:0022411 86 48 0,000 0,11853765 0,13352134 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,11853765 0,13345886 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,11853765 0,13339644 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,11853765 0,13333407 ! activation of caspase activity GO:0006919 84 48 0,000 0,11853765 0,13327177 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,11853765 0,13320952 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,11853765 0,13314733 ! regulation of lymphocyte differentiation GO:0045619 81 48 0,000 0,11853765 0,1330852 ! regulation of mast cell proliferation GO:0070666 81 48 0,000 0,11853765 0,13302313 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,12085351 0,13555876 ! regulation of action potential GO:0001508 95 49 0,000 0,12085351 0,13549559 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,12085351 0,13543248 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,12085351 0,13536943 ! regulation of ion transport GO:0043269 77 49 0,000 0,12085351 0,13530644 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,12085351 0,13524351 ! response to temperature stimulus GO:0009266 76 49 0,000 0,12085351 0,13518063 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,12085351 0,13511781 ! endocrine system development GO:0035270 104 49 0,000 0,12085351 0,13505506 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,12085351 0,13499236 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,12085351 0,13492972 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,12085351 0,13486713 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,12085351 0,13480461 ! neuromuscular process GO:0050905 99 50 0,000 0,12316336 0,13731744 ! regulation of ossification GO:0030278 117 50 0,000 0,12316336 0,13725384 ! inner ear development GO:0048839 79 50 0,000 0,12316336 0,13719029 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,12316336 0,13712681 ! negative regulation of immune system process GO:0002683 95 50 0,000 0,12316336 0,13706338 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,12316336 0,13700002 ! viral infectious cycle GO:0019058 99 51 0,000 0,12546721 0,13949821 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,12546721 0,13943377 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,12546721 0,1393694 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,12546721 0,13930508 ! excretion GO:0007588 83 51 0,000 0,12546721 0,13924083 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,12546721 0,13917663 ! chromatin remodeling GO:0006338 109 51 0,000 0,12546721 0,1391125 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,12546721 0,13904842 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,12546721 0,1389844 ! regulation of leukocyte proliferation GO:0070663 88 51 0,000 0,12546721 0,13892044 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of cell shape GO:0008360 125 51 0,000 0,12546721 0,13885654 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,12546721 0,1387927 ! regulation of angiogenesis GO:0045765 114 52 0,000 0,1277651 0,14126968 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,1277651 0,14120479 ! positive regulation of growth GO:0045927 90 52 0,000 0,1277651 0,14113995 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,1277651 0,14107518 ! amino acid activation GO:0043038 92 52 0,000 0,1277651 0,14101047 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,1277651 0,14094581 ! synapse organization GO:0050808 85 52 0,000 0,1277651 0,14088122 ! RNA catabolic process GO:0006401 93 53 0,000 0,13005702 0,14334273 ! regulation of translational initiation GO:0006446 82 53 0,000 0,13005702 0,1432771 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,13005702 0,14321152 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,13005702 0,14314601 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,13005702 0,14308056 ! regulation of neuron apoptosis GO:0043523 100 53 0,000 0,13005702 0,14301516 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,13005702 0,14294983 ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,13234299 0,145396 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,13234299 0,14532963 ! cell recognition GO:0008037 85 54 0,000 0,13234299 0,14526333 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,13234299 0,1451971 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,13234299 0,14513092 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,13234299 0,1450648 ! chloride transport GO:0006821 90 55 0,000 0,13462303 0,14749682 ! positive regulation of caspase activity GO:0043280 95 55 0,000 0,13462303 0,14742968 GO:0010952|positive regulation of peptidase activity, ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,13462303 0,14736261 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,13462303 0,14729559 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,13462303 0,14722864 ! aging GO:0007568 103 55 0,000 0,13462303 0,14716175 ! heart morphogenesis GO:0003007 97 55 0,000 0,13462303 0,14709492 ! RNA elongation GO:0006354 79 55 0,000 0,13462303 0,14702815 ! nuclear export GO:0051168 97 55 0,000 0,13462303 0,14696144 ! regulation of actin filament length GO:0030832 105 56 0,000 0,13689716 0,14937622 ! sensory perception of smell GO:0007608 80 56 0,000 0,13689716 0,1493085 ! skeletal muscle fiber development GO:0048741 111 56 0,000 0,13689716 0,14924085 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,13689716 0,14917326 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,13689716 0,14910573 ! regulation of DNA replication GO:0006275 101 56 0,000 0,13689716 0,14903826 ! proton transport GO:0015992 94 56 0,000 0,13689716 0,14897085 ! positive regulation of organelle organization GO:0010638 100 56 0,000 0,13689716 0,14890351 ! regulation of bone remodeling GO:0046850 137 57 0,000 0,13916538 0,15130226 ! muscle fiber development GO:0048747 112 57 0,000 0,13916538 0,15123392 ! regulation of intracellular transport GO:0032386 101 57 0,000 0,13916538 0,15116565 ! maintenance of location GO:0051235 118 57 0,000 0,13916538 0,15109743 ! hydrogen transport GO:0006818 97 58 0,000 0,14142772 0,15348448 ! regulation of tissue remodeling GO:0034103 140 58 0,000 0,14142772 0,15341528 ! regulation of endocytosis GO:0030100 91 58 0,000 0,14142772 0,15334615 ! adult behavior GO:0030534 99 58 0,000 0,14142772 0,15327707 ! positive regulation of secretion GO:0051047 95 59 0,000 0,14368419 0,15565248 ! regulation of cellular component size GO:0032535 109 59 0,000 0,14368419 0,15558243 ! skeletal system morphogenesis GO:0048705 105 59 0,000 0,14368419 0,15551244 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,14368419 0,15544252 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,14368419 0,15537266 ! DNA catabolic process GO:0006308 86 59 0,000 0,14368419 0,15530286 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,14368419 0,15523312 ! establishment of organelle localization GO:0051656 109 59 0,000 0,14368419 0,15516345 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,1459348 0,15752317 ! DNA damage response, signal transduction GO:0042770 128 60 0,000 0,1459348 0,15745253 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,1459348 0,15738195 ! regulation of heart contraction GO:0008016 110 60 0,000 0,1459348 0,15731144 ! camera-type eye development GO:0043010 116 60 0,000 0,1459348 0,15724099 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,1459348 0,15717061 ! kidney development GO:0001822 122 60 0,000 0,1459348 0,15710029 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,14817958 0,15944547 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,14817958 0,15937419 ! mesoderm development GO:0007498 119 61 0,000 0,14817958 0,15930298 ! tRNA processing GO:0008033 89 61 0,000 0,14817958 0,15923183 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,14817958 0,15916074 ! ear development GO:0043583 103 62 0,000 0,15041853 0,16149352 ! viral reproductive process GO:0022415 126 62 0,000 0,15041853 0,16142149 ! gonad development GO:0008406 98 62 0,000 0,15041853 0,16134952 ! regulation of homeostatic process GO:0032844 134 62 0,000 0,15041853 0,16127762 ! regulation of mitosis GO:0007088 105 63 0,000 0,15265166 0,16359907 GO:0051783|regulation of nuclear division, ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,15265166 0,16352622 ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,15265166 0,16345345 ! detection of external stimulus GO:0009581 91 63 0,000 0,15265166 0,16338074 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,15265166 0,16330809 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,154879 0,16561728 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,154879 0,16554371 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,154879 0,1654702 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,154879 0,16539675 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,15710056 0,16769475 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,15710056 0,16762038 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,15710056 0,16754608 GO:0035113|embryonic appendage morphogenesis, ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,15931636 0,16983392 ! actin filament organization GO:0007015 148 66 0,000 0,15931636 0,16975871 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,15931636 0,16968356 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,1615264 0,17196129 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,1615264 0,17188524 ! negative regulation of protein kinase activity GO:0006469 130 67 0,000 0,1615264 0,17180925 ! negative regulation of cell growth GO:0030308 132 67 0,000 0,1615264 0,17173333 ! activation of MAPK activity GO:0000187 115 67 0,000 0,1615264 0,17165748 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,1615264 0,17158169 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,1615264 0,17150597 ! adaptive immune response GO:0002250 119 67 0,000 0,1615264 0,17143032 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,1615264 0,17135473 ! amino acid transport GO:0006865 125 68 0,000 0,16373071 0,17361661 ! negative regulation of kinase activity GO:0033673 131 68 0,000 0,16373071 0,17354013 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,16373071 0,17346371 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,16373071 0,17338736 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! viral reproduction GO:0016032 134 68 0,000 0,16373071 0,17331108 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,16373071 0,17323487 ! cell cycle checkpoint GO:0000075 137 69 0,000 0,16592929 0,1754839 ! negative regulation of cell size GO:0045792 134 69 0,000 0,16592929 0,1754068 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,16592929 0,17532977 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,16592929 0,1752528 ! urogenital system development GO:0001655 137 69 0,000 0,16592929 0,1751759 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,16592929 0,17509907 ! antigen processing and presentation GO:0019882 104 69 0,000 0,16592929 0,17502231 ! appendage morphogenesis GO:0035107 135 70 0,000 0,16812217 0,17725764 GO:0035108|limb morphogenesis, ! amine catabolic process GO:0009310 117 71 0,000 0,17030936 0,17948502 ! reproductive structure development GO:0048608 113 71 0,000 0,17030936 0,17940644 ! appendage development GO:0048736 136 71 0,000 0,17030936 0,17932793 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,17030936 0,17924948 ! B cell activation GO:0042113 160 71 0,000 0,17030936 0,1791711 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,17030936 0,17909279 ! regulation of immune effector process GO:0002697 137 71 0,000 0,17030936 0,17901455 ! acute inflammatory response GO:0002526 113 72 0,000 0,17249086 0,18122839 ! regulation of caspase activity GO:0043281 122 72 0,000 0,17249086 0,18114929 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 0,000 0,17249086 0,18107025 ! carbohydrate transport GO:0008643 110 72 0,000 0,17249086 0,18099129 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,17249086 0,18091239 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,17249086 0,18083356 ! negative regulation of transferase activity GO:0051348 140 72 0,000 0,17249086 0,1807548 ! learning or memory GO:0007611 147 73 0,000 0,17466671 0,1829552 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,17466671 0,18287559 ! axon guidance GO:0007411 139 73 0,000 0,17466671 0,18279604 ! fertilization GO:0009566 90 73 0,000 0,17466671 0,18271656 ! transition metal ion transport GO:0000041 126 74 0,000 0,1768369 0,18490638 ! neurotransmitter transport GO:0006836 123 74 0,000 0,1768369 0,18482606 ! meiosis GO:0007126 121 74 0,000 0,1768369 0,1847458 GO:0051327|M phase of meiotic cell cycle, ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,1768369 0,18466562 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,1768369 0,1845855 ! regulation of endopeptidase activity GO:0052548 125 74 0,000 0,1768369 0,18450546 ! eye development GO:0001654 143 74 0,000 0,1768369 0,18442548 ! organelle localization GO:0051640 136 74 0,000 0,1768369 0,18434557 ! cell-matrix adhesion GO:0007160 163 75 0,000 0,17900146 0,18652123 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,17900146 0,18644048 ! phosphoinositide-mediated signaling GO:0048015 131 75 0,000 0,17900146 0,18635981 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,17900146 0,1862792 ! meiotic cell cycle GO:0051321 122 75 0,000 0,17900146 0,18619867 ! rhythmic process GO:0048511 128 75 0,000 0,17900146 0,1861182 ! lymphocyte differentiation GO:0030098 167 75 0,000 0,17900146 0,1860378 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,1811604 0,18820031 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,1811604 0,18811909 ! defense response to bacterium GO:0042742 89 76 0,000 0,1811604 0,18803793 ! regulation of catabolic process GO:0009894 161 76 0,000 0,1811604 0,18795685 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,18331374 0,19010899 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,18331374 0,19002708 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,18331374 0,18994524 ! positive regulation of lymphocyte activation GO:0051251 127 77 0,000 0,18331374 0,18986347 ! blood coagulation GO:0007596 146 78 0,000 0,18546148 0,1920053 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,18546148 0,19192272 ! negative regulation of organelle organization GO:0010639 161 78 0,000 0,18546148 0,19184021 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,18546148 0,19175777 ! protein oligomerization GO:0051259 139 78 0,000 0,18546148 0,1916754 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,18760365 0,19380609 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,18760365 0,19372291 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,18760365 0,1936398 ! regulation of peptidase activity GO:0052547 134 79 0,000 0,18760365 0,19355676 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 0,000 0,18760365 0,1934738 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,18760365 0,19339091 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,18974025 0,19550966 ! response to metal ion GO:0010038 140 80 0,000 0,18974025 0,19542596 ! muscle cell differentiation GO:0042692 159 80 0,000 0,18974025 0,19534234 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,18974025 0,19525879 ! protein import into nucleus GO:0006606 158 80 0,000 0,18974025 0,19517531 ! inorganic anion transport GO:0015698 138 80 0,000 0,18974025 0,1950919 ! T cell activation GO:0042110 168 81 0,000 0,19187131 0,19719879 ! digestion GO:0007586 112 81 0,000 0,19187131 0,19711459 ! cell-substrate adhesion GO:0031589 171 81 0,000 0,19187131 0,19703046 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,19187131 0,1969464 ! nuclear import GO:0051170 161 81 0,000 0,19187131 0,19686242 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,19399683 0,19895838 ! response to drug GO:0042493 143 82 0,000 0,19399683 0,19887361 ! response to nutrient GO:0007584 125 82 0,000 0,19399683 0,19878891 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,19399683 0,19870429 ! regulation of lyase activity GO:0051339 160 83 0,000 0,19611683 0,20079025 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,19823133 0,20286881 ! hemostasis GO:0007599 158 84 0,000 0,19823133 0,20278256 ! negative regulation of transport GO:0051051 153 84 0,000 0,19823133 0,20269638 ! negative regulation of growth GO:0045926 155 84 0,000 0,19823133 0,20261027 ! regulation of ligase activity GO:0051340 142 84 0,000 0,19823133 0,20252423 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,19823133 0,20243827 ! response to unfolded protein GO:0006986 131 85 0,000 0,20034033 0,20450523 ! nucleosome assembly GO:0006334 122 85 0,000 0,20034033 0,20441851 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,20034033 0,20433185 ! positive regulation of cell activation GO:0050867 145 85 0,000 0,20034033 0,20424527 GO:0002696|positive regulation of leukocyte activation, ! amine biosynthetic process GO:0009309 138 86 0,000 0,20244386 0,20630238 ! response to inorganic substance GO:0010035 153 86 0,000 0,20244386 0,20621504 ! chromatin assembly GO:0031497 124 86 0,000 0,20244386 0,20612777 ! tube morphogenesis GO:0035239 176 86 0,000 0,20244386 0,20604058 ! mitochondrion organization GO:0007005 148 86 0,000 0,20244386 0,20595345 ! amine transport GO:0015837 155 86 0,000 0,20244386 0,20586641 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,20454192 0,20791207 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,20454192 0,20782427 ! protein localization in nucleus GO:0034504 176 87 0,000 0,20454192 0,20773654 ! regulation of protein transport GO:0051223 154 87 0,000 0,20454192 0,20764889 GO:0070201|regulation of establishment of protein localization, ! positive regulation of protein modification process GO:0031401 136 88 0,000 0,20663453 0,20968481 ! gland development GO:0048732 206 88 0,000 0,20663453 0,20959641 ! regulation of neurological system process GO:0031644 148 88 0,000 0,20663453 0,20950809 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,20663453 0,20941984 ! cellular defense response GO:0006968 114 89 0,000 0,20872171 0,21144608 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,21080347 0,21346513 ! regulation of cell cycle process GO:0010564 149 90 0,000 0,21080347 0,21337532 ! sex differentiation GO:0007548 145 90 0,000 0,21080347 0,2132856 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,21080347 0,21319594 ! response to protein stimulus GO:0051789 149 91 0,000 0,21287982 0,2152054 ! regulation of defense response GO:0031347 149 92 0,000 0,21495077 0,21720771 ! nucleosome organization GO:0034728 138 92 0,000 0,21495077 0,21711652 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,21495077 0,21702541 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,21701635 0,21901902 GO:0010498|proteasomal protein catabolic process, ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,21701635 0,21892718 ! negative regulation of multicellular organismal process GO:0051241 166 93 0,000 0,21701635 0,21883543 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,21907656 0,22082036 ! female pregnancy GO:0007565 164 94 0,000 0,21907656 0,22072789 ! transcription initiation GO:0006352 153 94 0,000 0,21907656 0,22063549 ! regulation of T cell activation GO:0050863 158 94 0,000 0,21907656 0,22054318 ! forebrain development GO:0030900 188 95 0,000 0,22113141 0,22251869 ! leukocyte differentiation GO:0002521 202 96 0,000 0,22318093 0,22448717 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,22318093 0,22439336 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,22318093 0,22429963 ! positive regulation of immune response GO:0050778 156 96 0,000 0,22318093 0,22420598 ! detection of stimulus GO:0051606 151 96 0,000 0,22318093 0,2241124 ! regulation of DNA metabolic process GO:0051052 178 97 0,000 0,22522512 0,22607077 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,22522512 0,2259765 ! protein ubiquitination GO:0016567 217 97 0,000 0,22522512 0,2258823 ! hormone metabolic process GO:0042445 157 97 0,000 0,22522512 0,22578819 ! regulation of protein localization GO:0032880 176 97 0,000 0,22522512 0,22569415 ! response to virus GO:0009615 160 98 0,000 0,227264 0,22764246 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,227264 0,22754773 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,227264 0,22745308 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,22929759 0,22939293 ! cell cycle arrest GO:0007050 213 100 0,000 0,23132589 0,23132589