pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6731-Wang-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! induction of apoptosis by intracellular signals GO:0008629 67 40 5,000 7,578E-07 1,743E-03 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 3,000 8,201E-07 9,431E-04 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 4,000 9,515E-07 7,295E-04 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 2,000 5,076E-06 2,919E-03 ! regulation of DNA metabolic process GO:0051052 135 85 6,000 5,585E-06 2,569E-03 ! meiosis GO:0007126 96 61 5,000 9,54E-06 3,657E-03 GO:0051327|M phase of meiotic cell cycle, ! hormone-mediated signaling GO:0009755 49 36 4,000 9,799E-06 3,22E-03 ! prostate gland development GO:0030850 9 6 2,000 1,009E-05 2,901E-03 ! male meiosis GO:0007140 7 6 2,000 1,009E-05 2,579E-03 ! regulation of protein export from nucleus GO:0046825 6 6 2,000 1,009E-05 2,321E-03 ! ER overload response GO:0006983 7 6 2,000 1,009E-05 2,11E-03 ! negative regulation of focal adhesion formation GO:0051895 16 6 2,000 1,009E-05 1,934E-03 ! blastocyst growth GO:0001832 15 6 2,000 1,009E-05 1,785E-03 ! meiotic cell cycle GO:0051321 97 62 5,000 1,049E-05 1,724E-03 ! double-strand break repair GO:0006302 67 40 4,000 1,667E-05 2,555E-03 ! G1 DNA damage checkpoint GO:0031571 18 7 2,000 1,756E-05 2,524E-03 ! regulation of focal adhesion formation GO:0051893 17 7 2,000 1,756E-05 2,375E-03 ! response to endoplasmic reticulum stress GO:0034976 25 21 3,000 2,181E-05 2,787E-03 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 3,000 2,649E-05 3,207E-03 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 2,000 2,792E-05 3,211E-03 ! cellular response to hormone stimulus GO:0032870 109 74 5,000 2,921E-05 3,199E-03 ! ER-nuclear signaling pathway GO:0006984 27 23 3,000 3,187E-05 3,332E-03 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 2,000 5,913E-05 5,913E-03 GO:0010812|negative regulation of cell-substrate adhesion, ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 2,000 5,913E-05 5,667E-03 ! response to X-ray GO:0010165 16 10 2,000 5,913E-05 5,44E-03 ! protein sumoylation GO:0016925 12 10 2,000 5,913E-05 5,231E-03 ! double-strand break repair via homologous recombination GO:0000724 16 11 2,000 8,082E-05 6,885E-03 GO:0000725|recombinational repair, ! oxygen transport GO:0015671 15 11 2,000 8,082E-05 6,639E-03 ! DNA damage response, signal transduction GO:0042770 96 56 4,000 8,724E-05 6,919E-03 ! response to gamma radiation GO:0010332 20 12 2,000 1,071E-04 8,213E-03 ! negative regulation of DNA metabolic process GO:0051053 48 32 3,000 1,223E-04 9,077E-03 ! regulation of protein stability GO:0031647 48 32 3,000 1,223E-04 8,793E-03 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 5,000 1,339E-04 9,331E-03 ! gas transport GO:0015669 18 13 2,000 1,384E-04 9,365E-03 ! regulation of intracellular protein transport GO:0033157 59 35 3,000 1,748E-04 0,01148881 ! inositol metabolic process GO:0006020 20 14 2,000 1,752E-04 0,01119098 ! G1/S transition checkpoint GO:0031575 33 14 2,000 1,752E-04 0,01088852 ! release of cytochrome c from mitochondria GO:0001836 23 14 2,000 1,752E-04 0,01060198 ! cardiac muscle tissue development GO:0048738 23 15 2,000 2,177E-04 0,01283651 ! endothelial cell migration GO:0043542 22 16 2,000 2,663E-04 0,01531298 ! fructose metabolic process GO:0006000 20 16 2,000 2,663E-04 0,0149395 ! oogenesis GO:0048477 23 16 2,000 2,663E-04 0,01458379 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 2,000 3,215E-04 0,01719511 ! energy reserve metabolic process GO:0006112 59 41 3,000 3,257E-04 0,0170256 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 3,000 3,578E-04 0,01828517 ! apoptotic mitochondrial changes GO:0008637 29 18 2,000 3,835E-04 0,01917478 ! gland development GO:0048732 148 77 4,000 3,941E-04 0,01928577 ! glycolysis GO:0006096 53 44 3,000 4,285E-04 0,02053289 ! reciprocal meiotic recombination GO:0007131 31 19 2,000 4,527E-04 0,02125007 ! apoptotic nuclear changes GO:0030262 24 19 2,000 4,527E-04 0,02082507 ! positive regulation of intracellular transport GO:0032388 29 19 2,000 4,527E-04 0,02041673 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 2,000 4,527E-04 0,0200241 ! cell maturation GO:0048469 60 45 3,000 4,674E-04 0,02028321 ! response to UV GO:0009411 75 46 3,000 5,087E-04 0,02166808 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 3,000 5,526E-04 0,02310866 ! regulation of DNA replication GO:0006275 75 48 3,000 5,991E-04 0,02460552 ! cell aging GO:0007569 32 21 2,000 6,141E-04 0,02477886 ! transcription initiation GO:0006352 118 85 4,000 6,215E-04 0,02464408 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 1,000 6,357E-04 0,02478247 ! glial cell fate commitment GO:0021781 12 5 1,000 6,357E-04 0,02436943 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 1,000 6,357E-04 0,02396993 ! positive regulation of viral genome replication GO:0045070 8 5 1,000 6,357E-04 0,02358332 ! regulation of retroviral genome replication GO:0045091 6 5 1,000 6,357E-04 0,02320898 ! negative regulation of survival gene product expression GO:0008634 6 5 1,000 6,357E-04 0,02284634 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 1,000 6,357E-04 0,02249486 ! regulation of appetite GO:0032098 5 5 1,000 6,357E-04 0,02215403 ! attachment of GPI anchor to protein GO:0016255 9 5 1,000 6,357E-04 0,02182337 ! early endosome to late endosome transport GO:0045022 11 5 1,000 6,357E-04 0,02150244 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 1,000 6,357E-04 0,02119081 ! monocyte differentiation GO:0030224 8 5 1,000 6,357E-04 0,02088808 ! centrosome duplication GO:0051298 5 5 1,000 6,357E-04 0,02059388 ! response to UV-C GO:0010225 6 5 1,000 6,357E-04 0,02030786 ! regulation of sterol transport GO:0032371 7 5 1,000 6,357E-04 0,02002967 GO:0032374|regulation of cholesterol transport, ! apical protein localization GO:0045176 6 5 1,000 6,357E-04 0,019759 ! spindle assembly GO:0051225 5 5 1,000 6,357E-04 0,01949554 ! receptor biosynthetic process GO:0032800 6 5 1,000 6,357E-04 0,01923902 ! RNA elongation GO:0006354 62 49 3,000 6,483E-04 0,0193646 ! regulation of intracellular transport GO:0032386 78 49 3,000 6,483E-04 0,01911633 ! Wnt receptor signaling pathway GO:0016055 130 87 4,000 6,911E-04 0,020121 ! regulation of cell-matrix adhesion GO:0001952 51 22 2,000 7,069E-04 0,02032228 GO:0010810|regulation of cell-substrate adhesion, ! blastocyst development GO:0001824 37 22 2,000 7,069E-04 0,02007139 ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 3,000 7,552E-04 0,02118176 ! regulation of protein catabolic process GO:0042176 77 51 3,000 7,552E-04 0,02092656 ! negative regulation of DNA replication GO:0008156 35 23 2,000 8,081E-04 0,02212684 ! nucleotide-excision repair GO:0006289 64 52 3,000 8,13E-04 0,02199967 ! fat cell differentiation GO:0045444 37 24 2,000 9,181E-04 0,02455451 ! receptor metabolic process GO:0043112 37 24 2,000 9,181E-04 0,02427228 ! base-excision repair GO:0006284 31 24 2,000 9,181E-04 0,02399646 ! glucose catabolic process GO:0006007 66 54 3,000 9,38E-04 0,02424067 ! regulation of helicase activity GO:0051095 11 6 1,000 9,485E-04 0,02424048 ! cytokinesis during cell cycle GO:0033205 9 6 1,000 9,485E-04 0,0239741 ! meiotic prophase I GO:0007128 9 6 1,000 9,485E-04 0,02371351 ! activation of caspase activity by cytochrome c GO:0008635 10 6 1,000 9,485E-04 0,02345853 ! response to dietary excess GO:0002021 7 6 1,000 9,485E-04 0,02320897 ! negative regulation of DNA recombination GO:0045910 9 6 1,000 9,485E-04 0,02296467 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 1,000 9,485E-04 0,02272545 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! eating behavior GO:0042755 6 6 1,000 9,485E-04 0,02249117 ! DNA topological change GO:0006265 8 6 1,000 9,485E-04 0,02226167 ! establishment of chromosome localization GO:0051303 9 6 1,000 9,485E-04 0,0220368 GO:0050000|chromosome localization, ! negative regulation of neuroblast proliferation GO:0007406 18 6 1,000 9,485E-04 0,02181643 ! adult feeding behavior GO:0008343 6 6 1,000 9,485E-04 0,02160043 ! catecholamine transport GO:0051937 7 6 1,000 9,485E-04 0,02138866 ! regulation of cellular ketone metabolic process GO:0010565 34 25 2,000 1,037E-03 0,02316061 ! in utero embryonic development GO:0001701 147 96 4,000 1,079E-03 0,023864 ! developmental maturation GO:0021700 75 57 3,000 1,15E-03 0,02518955 ! negative regulation of protein kinase cascade GO:0010741 51 26 2,000 1,166E-03 0,02529112 ! response to ionizing radiation GO:0010212 47 27 2,000 1,304E-03 0,02802107 ! negative regulation of protein transport GO:0051224 49 27 2,000 1,304E-03 0,02776161 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 1,000 1,321E-03 0,02787293 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 1,000 1,321E-03 0,02761954 GO:0016446|somatic hypermutation of immunoglobulin genes, ! regulation of gluconeogenesis GO:0006111 7 7 1,000 1,321E-03 0,02737071 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 1,000 1,321E-03 0,02712633 ! lipoprotein transport GO:0042953 9 7 1,000 1,321E-03 0,02688628 ! regulation of response to extracellular stimulus GO:0032104 10 7 1,000 1,321E-03 0,02665043 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 1,000 1,321E-03 0,02641869 ! asymmetric protein localization GO:0008105 8 7 1,000 1,321E-03 0,02619094 ! positive regulation of mitotic cell cycle GO:0045931 11 7 1,000 1,321E-03 0,02596709 ! B cell lineage commitment GO:0002326 17 7 1,000 1,321E-03 0,02574703 ! regulation of fat cell differentiation GO:0045598 9 7 1,000 1,321E-03 0,02553067 ! T cell lineage commitment GO:0002360 12 7 1,000 1,321E-03 0,02531791 ! regulation of lipid transport GO:0032368 13 7 1,000 1,321E-03 0,02510867 ! response to tumor cell GO:0002347 12 7 1,000 1,321E-03 0,02490286 ! phosphoinositide metabolic process GO:0030384 87 60 3,000 1,393E-03 0,02605531 ! neurotransmitter uptake GO:0001504 10 8 1,000 1,752E-03 0,03249563 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 1,000 1,752E-03 0,03223566 ! membrane hyperpolarization GO:0060081 10 8 1,000 1,752E-03 0,03197982 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 1,000 1,752E-03 0,03172801 ! middle ear morphogenesis GO:0042474 9 8 1,000 1,752E-03 0,03148014 ! multicellular organism growth GO:0035264 14 8 1,000 1,752E-03 0,03123611 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 1,000 1,752E-03 0,03099583 ! phosphoinositide 3-kinase cascade GO:0014065 23 8 1,000 1,752E-03 0,03075922 ! prophase GO:0051324 11 8 1,000 1,752E-03 0,0305262 ! regulation of telomere maintenance GO:0032204 10 8 1,000 1,752E-03 0,03029668 ! hexose catabolic process GO:0019320 82 64 3,000 1,771E-03 0,03039821 ! reproductive structure development GO:0048608 90 65 3,000 1,875E-03 0,03195274 ! protein oligomerization GO:0051259 100 65 3,000 1,875E-03 0,0317178 ! DNA damage checkpoint GO:0000077 53 31 2,000 1,957E-03 0,03284954 ! mammary gland development GO:0030879 57 31 2,000 1,957E-03 0,0326115 ! meiosis I GO:0007127 52 32 2,000 2,146E-03 0,0355168 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 1,000 2,241E-03 0,03680979 ! receptor clustering GO:0043113 15 9 1,000 2,241E-03 0,03654872 ! epithelial cell development GO:0002064 10 9 1,000 2,241E-03 0,03629134 ! motor axon guidance GO:0008045 14 9 1,000 2,241E-03 0,03603755 ! DNA ligation GO:0006266 14 9 1,000 2,241E-03 0,03578729 ! postreplication repair GO:0006301 11 9 1,000 2,241E-03 0,03554048 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 1,000 2,241E-03 0,03529706 ! oocyte differentiation GO:0009994 12 9 1,000 2,241E-03 0,03505694 GO:0048599|oocyte development, ! negative regulation of BMP signaling pathway GO:0030514 13 9 1,000 2,241E-03 0,03482007 ! negative regulation of cell adhesion GO:0007162 67 33 2,000 2,347E-03 0,03623288 ! carbohydrate homeostasis GO:0033500 39 33 2,000 2,347E-03 0,03599132 GO:0042593|glucose homeostasis, ! nucleus organization GO:0006997 49 33 2,000 2,347E-03 0,03575297 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 3,000 2,462E-03 0,03725986 ! regulation of catabolic process GO:0009894 106 70 3,000 2,462E-03 0,03701633 ! mitotic cell cycle checkpoint GO:0007093 63 34 2,000 2,559E-03 0,03822384 ! DNA integrity checkpoint GO:0031570 57 34 2,000 2,559E-03 0,03797723 ! female gamete generation GO:0007292 43 34 2,000 2,559E-03 0,03773379 ! polyol metabolic process GO:0019751 44 34 2,000 2,559E-03 0,03749344 ! phosphoinositide-mediated signaling GO:0048015 109 71 3,000 2,593E-03 0,03775033 ! monosaccharide catabolic process GO:0046365 91 71 3,000 2,593E-03 0,03751291 ! glycogen metabolic process GO:0005977 48 35 2,000 2,783E-03 0,04000394 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 1,000 2,786E-03 0,03979946 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 1,000 2,786E-03 0,03955378 ! mRNA polyadenylation GO:0006378 18 10 1,000 2,786E-03 0,03931112 ! positive regulation of viral reproduction GO:0048524 15 10 1,000 2,786E-03 0,03907142 ! cytoplasmic sequestering of protein GO:0051220 14 10 1,000 2,786E-03 0,03883462 ! glucan metabolic process GO:0044042 49 36 2,000 3,018E-03 0,04181709 GO:0006073|cellular glucan metabolic process, ! regulation of protein transport GO:0051223 114 76 3,000 3,32E-03 0,04572293 GO:0070201|regulation of establishment of protein localization, ! RNA polyadenylation GO:0043631 19 11 1,000 3,387E-03 0,04637107 ! detection of mechanical stimulus GO:0050982 15 11 1,000 3,387E-03 0,04609668 ! dopamine receptor signaling pathway GO:0007212 22 11 1,000 3,387E-03 0,04582552 ! regulation of mRNA processing GO:0050684 18 11 1,000 3,387E-03 0,04555754 ! regulation of intracellular pH GO:0051453 17 11 1,000 3,387E-03 0,04529267 ! actin cytoskeleton reorganization GO:0031532 21 11 1,000 3,387E-03 0,04503086 ! nitric oxide metabolic process GO:0046209 14 11 1,000 3,387E-03 0,04477206 GO:0006809|nitric oxide biosynthetic process, ! histone deacetylation GO:0016575 13 11 1,000 3,387E-03 0,04451622 ! chromatin silencing GO:0006342 19 11 1,000 3,387E-03 0,04426329 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 1,000 3,387E-03 0,04401321 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! negative regulation of mast cell proliferation GO:0070667 17 11 1,000 3,387E-03 0,04376595 GO:0042130|negative regulation of T cell proliferation, ! mRNA 3'-end processing GO:0031124 19 11 1,000 3,387E-03 0,04352145 ! regulation of steroid biosynthetic process GO:0050810 11 11 1,000 3,387E-03 0,04327966 ! pigmentation GO:0043473 74 38 2,000 3,524E-03 0,0447843 ! regulation of epithelial cell proliferation GO:0050678 71 39 2,000 3,796E-03 0,04796766 ! developmental growth GO:0048589 62 39 2,000 3,796E-03 0,04770554 ! alcohol catabolic process GO:0046164 104 80 3,000 3,993E-03 0,04990728 ! non-recombinational repair GO:0000726 19 12 1,000 4,043E-03 0,05026556 GO:0006303|double-strand break repair via nonhomologous end joining, ! monoamine transport GO:0015844 13 12 1,000 4,043E-03 0,04999531 ! immunoglobulin production during immune response GO:0002381 20 12 1,000 4,043E-03 0,04972796 ! regulation of fatty acid oxidation GO:0046320 18 12 1,000 4,043E-03 0,04946345 ! RNA 3'-end processing GO:0031123 20 12 1,000 4,043E-03 0,04920173 ! regulation of myeloid cell differentiation GO:0045637 69 40 2,000 4,079E-03 0,04938318 ! positive regulation of protein transport GO:0051222 55 40 2,000 4,079E-03 0,04912463 ! epithelial cell differentiation GO:0030855 55 41 2,000 4,376E-03 0,0524188 ! regulation of cell adhesion GO:0030155 159 83 3,000 4,554E-03 0,05426749 ! positive regulation of protein import into nucleus GO:0042307 23 13 1,000 4,753E-03 0,05635043 ! regulation of cellular pH GO:0030641 20 13 1,000 4,753E-03 0,05606145 ! cellular pigmentation GO:0033059 24 13 1,000 4,753E-03 0,05577542 ! rRNA metabolic process GO:0016072 107 85 3,000 4,956E-03 0,05786171 GO:0006364|rRNA processing, ! regulation of protein localization GO:0032880 132 85 3,000 4,956E-03 0,05756948 ! activation of caspase activity GO:0006919 65 43 2,000 5,007E-03 0,05786849 ! DNA-dependent DNA replication GO:0006261 59 43 2,000 5,007E-03 0,05757915 ! response to insulin stimulus GO:0032868 63 43 2,000 5,007E-03 0,05729268 ! cell cycle arrest GO:0007050 150 86 3,000 5,166E-03 0,05881802 ! negative regulation of cell migration GO:0030336 92 44 2,000 5,342E-03 0,06052382 ! regulation of S phase GO:0033261 18 14 1,000 5,516E-03 0,06219036 ! regulation of lipid biosynthetic process GO:0046890 16 14 1,000 5,516E-03 0,061887 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 1,000 5,516E-03 0,06158657 ! epidermis morphogenesis GO:0048730 29 14 1,000 5,516E-03 0,06128905 ! cellular response to starvation GO:0009267 21 14 1,000 5,516E-03 0,0609944 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 1,000 5,516E-03 0,06070256 ! DNA unwinding during replication GO:0006268 21 14 1,000 5,516E-03 0,0604135 ! synaptic transmission, cholinergic GO:0007271 21 14 1,000 5,516E-03 0,06012718 ! regulation of erythrocyte differentiation GO:0045646 27 14 1,000 5,516E-03 0,05984356 ! muscle maintenance GO:0046716 19 14 1,000 5,516E-03 0,0595626 ! positive regulation of cell cycle GO:0045787 77 45 2,000 5,69E-03 0,06115488 ! protein amino acid autophosphorylation GO:0046777 80 45 2,000 5,69E-03 0,06087044 ! reproductive developmental process GO:0003006 127 89 3,000 5,831E-03 0,06208501 ! protein modification by small protein conjugation GO:0032446 140 90 3,000 6,064E-03 0,06427576 ! embryonic hindlimb morphogenesis GO:0035116 25 15 1,000 6,331E-03 0,06679649 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 1,000 6,331E-03 0,06649149 ! regulation of neurotransmitter secretion GO:0046928 26 15 1,000 6,331E-03 0,06618925 ! bile acid metabolic process GO:0008206 22 15 1,000 6,331E-03 0,06588976 ! centrosome cycle GO:0007098 16 15 1,000 6,331E-03 0,06559295 ! regulation of survival gene product expression GO:0045884 20 15 1,000 6,331E-03 0,06529882 ! peptidyl-serine phosphorylation GO:0018105 23 15 1,000 6,331E-03 0,0650073 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 1,000 6,331E-03 0,06471838 ! dopamine metabolic process GO:0042417 30 15 1,000 6,331E-03 0,06443202 ! regulation of BMP signaling pathway GO:0030510 21 15 1,000 6,331E-03 0,06414818 ! negative regulation of leukocyte proliferation GO:0070664 25 15 1,000 6,331E-03 0,06386682 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 29 15 1,000 6,331E-03 0,06358793 ! covalent chromatin modification GO:0016569 75 47 2,000 6,426E-03 0,0642648 ! glycerophospholipid metabolic process GO:0006650 130 92 3,000 6,55E-03 0,06521825 ! cell fate commitment GO:0045165 141 92 3,000 6,55E-03 0,06493714 ! DNA recombination GO:0006310 146 92 3,000 6,55E-03 0,06465844 ! carbohydrate catabolic process GO:0016052 121 93 3,000 6,803E-03 0,06686251 ! positive regulation of caspase activity GO:0043280 72 48 2,000 6,815E-03 0,06669973 GO:0010952|positive regulation of peptidase activity, ! cellular polysaccharide metabolic process GO:0044264 63 48 2,000 6,815E-03 0,0664171 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 2,000 6,815E-03 0,06613686 ! regulation of glucose metabolic process GO:0010906 22 16 1,000 7,198E-03 0,06955616 ! protein amino acid deacetylation GO:0006476 20 16 1,000 7,198E-03 0,06926513 ! cellular response to unfolded protein GO:0034620 19 16 1,000 7,198E-03 0,06897653 GO:0030968|endoplasmic reticulum unfolded protein response, ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 1,000 7,198E-03 0,06869032 ! regulation of steroid metabolic process GO:0019218 21 16 1,000 7,198E-03 0,06840647 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 1,000 7,198E-03 0,06812497 ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 1,000 7,198E-03 0,06784577 ! regulation of cellular component biogenesis GO:0044087 158 96 3,000 7,598E-03 0,07132817 ! protein modification by small protein conjugation or removal GO:0070647 148 96 3,000 7,598E-03 0,07103821 ! response to light stimulus GO:0009416 153 96 3,000 7,598E-03 0,07075061 ! regulation of actin filament length GO:0030832 72 50 2,000 7,633E-03 0,070791 ! lipid modification GO:0030258 73 50 2,000 7,633E-03 0,0705067 ! adult behavior GO:0030534 80 51 2,000 8,063E-03 0,07417949 ! negative regulation of cell motion GO:0051271 104 51 2,000 8,063E-03 0,07388395 ! signal complex assembly GO:0007172 29 17 1,000 8,114E-03 0,07405964 ! regulation of viral genome replication GO:0045069 24 17 1,000 8,114E-03 0,07376692 ! DNA duplex unwinding GO:0032508 25 17 1,000 8,114E-03 0,0734765 GO:0032392|DNA geometric change, ! neuromuscular junction development GO:0007528 23 17 1,000 8,114E-03 0,07318835 ! negative regulation of protein catabolic process GO:0042177 26 17 1,000 8,114E-03 0,07290246 ! long-chain fatty acid transport GO:0015909 24 17 1,000 8,114E-03 0,0726188 ! negative regulation of intracellular transport GO:0032387 29 17 1,000 8,114E-03 0,07233733 ! peptidyl-serine modification GO:0018209 27 17 1,000 8,114E-03 0,07205803 ! regulation of cellular component size GO:0032535 74 52 2,000 8,507E-03 0,07525302 ! aging GO:0007568 79 52 2,000 8,507E-03 0,07496469 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 1,000 9,081E-03 0,07971624 ! positive regulation of anti-apoptosis GO:0045768 29 18 1,000 9,081E-03 0,07941313 ! transcription from RNA polymerase III promoter GO:0006383 32 18 1,000 9,081E-03 0,07911233 ! central nervous system neuron development GO:0021954 30 18 1,000 9,081E-03 0,07881379 ! cellular response to nutrient levels GO:0031669 27 18 1,000 9,081E-03 0,0785175 ! negative regulation of T cell activation GO:0050868 25 18 1,000 9,081E-03 0,07822342 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 1,000 9,081E-03 0,07793155 ! positive regulation of protein catabolic process GO:0045732 23 19 1,000 0,01009578 0,08632078 ! regulation of carbohydrate metabolic process GO:0006109 28 19 1,000 0,01009578 0,08600107 GO:0010675|regulation of cellular carbohydrate metabolic process, ! response to alkaloid GO:0043279 32 19 1,000 0,01009578 0,08568373 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 1,000 0,01009578 0,08536871 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 1,000 0,01009578 0,08505601 ! cell structure disassembly during apoptosis GO:0006921 24 19 1,000 0,01009578 0,08474558 ! response to starvation GO:0042594 30 19 1,000 0,01009578 0,08443742 ! regulation of fatty acid metabolic process GO:0019217 28 19 1,000 0,01009578 0,08413148 ! somatic diversification of immunoglobulins GO:0016445 29 19 1,000 0,01009578 0,08382776 ! protein stabilization GO:0050821 26 19 1,000 0,01009578 0,08352622 ! regulation of lipid metabolic process GO:0019216 84 56 2,000 0,01042425 0,08593469 ! chromosome segregation GO:0007059 83 57 2,000 0,01093949 0,0898601 ! response to peptide hormone stimulus GO:0043434 84 57 2,000 0,01093949 0,08954031 ! hindlimb morphogenesis GO:0035137 32 20 1,000 0,0111587 0,09101068 ! regulation of neurotransmitter transport GO:0051588 35 20 1,000 0,0111587 0,09068909 ! central nervous system neuron differentiation GO:0021953 33 20 1,000 0,0111587 0,09036976 ! chromosome condensation GO:0030261 31 20 1,000 0,0111587 0,09005267 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 1,000 0,01226866 0,09866405 GO:0016444|somatic cell DNA recombination, ! myeloid leukocyte differentiation GO:0002573 33 21 1,000 0,01226866 0,09832027 ! DNA catabolic process, endonucleolytic GO:0000737 26 21 1,000 0,01226866 0,09797888 ! regulation of DNA recombination GO:0000018 40 21 1,000 0,01226866 0,09763986 ! activation of pro-apoptotic gene products GO:0008633 36 21 1,000 0,01226866 0,09730317 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 1,000 0,01226866 0,09696879 ! regulation of insulin secretion GO:0050796 26 21 1,000 0,01226866 0,09663671 ! cholesterol biosynthetic process GO:0006695 29 21 1,000 0,01226866 0,09630689 ! fatty acid transport GO:0015908 30 21 1,000 0,01226866 0,09597932 ! immunoglobulin production GO:0002377 33 21 1,000 0,01226866 0,09565396 GO:0002440|production of molecular mediator of immune response, ! cellular response to extracellular stimulus GO:0031668 32 21 1,000 0,01226866 0,09533081 ! nerve-nerve synaptic transmission GO:0007270 36 21 1,000 0,01226866 0,09500983 ! regulation of homeostatic process GO:0032844 105 60 2,000 0,01257251 0,09703616 ! urogenital system development GO:0001655 101 61 2,000 0,01314616 0,10112432 ! fatty acid biosynthetic process GO:0006633 92 61 2,000 0,01314616 0,10078724 ! protein import into nucleus, translocation GO:0000060 36 22 1,000 0,01342484 0,10258183 ! regulation of fibroblast proliferation GO:0048145 35 22 1,000 0,01342484 0,10224216 ! regulation of anti-apoptosis GO:0045767 36 22 1,000 0,01342484 0,10190473 ! microtubule organizing center organization GO:0031023 28 22 1,000 0,01342484 0,10156951 GO:0051297|centrosome organization, ! barbed-end actin filament capping GO:0051016 33 22 1,000 0,01342484 0,1012365 GO:0051693|actin filament capping, ! membrane depolarization GO:0051899 35 22 1,000 0,01342484 0,10090566 ! protein tetramerization GO:0051262 39 22 1,000 0,01342484 0,10057698 ! positive regulation of cell adhesion GO:0045785 37 23 1,000 0,01462643 0,10922337 ! myelination GO:0042552 35 23 1,000 0,01462643 0,10886989 ! cellular iron ion homeostasis GO:0006879 37 23 1,000 0,01462643 0,1085187 ! regulation of transcription factor import into nucleus GO:0042990 46 23 1,000 0,01462643 0,10816976 ! regulation of viral reproduction GO:0050792 32 23 1,000 0,01462643 0,10782307 ! hydrogen peroxide metabolic process GO:0042743 30 23 1,000 0,01462643 0,10747858 ! cell fate determination GO:0001709 45 23 1,000 0,01462643 0,1071363 ! somatic diversification of immune receptors GO:0002200 35 23 1,000 0,01462643 0,10679618 ! negative regulation of catabolic process GO:0009895 34 23 1,000 0,01462643 0,10645822 ! cell cycle checkpoint GO:0000075 108 64 2,000 0,01495579 0,10851203 ! regulation of actin cytoskeleton organization GO:0032956 97 64 2,000 0,01495579 0,1081708 ! regulation of caspase activity GO:0043281 97 65 2,000 0,01558871 0,11239507 ! B cell activation GO:0042113 104 65 2,000 0,01558871 0,11204383 ! response to toxin GO:0009636 38 24 1,000 0,01587264 0,11372922 ! mitochondrial membrane organization GO:0007006 39 24 1,000 0,01587264 0,11337602 ! negative regulation of cell development GO:0010721 56 24 1,000 0,01587264 0,11302501 GO:0050768|negative regulation of neurogenesis, ! regulation of actin filament-based process GO:0032970 99 66 2,000 0,01623654 0,11525941 ! regulation of endopeptidase activity GO:0052548 99 67 2,000 0,01689933 0,11959527 ! negative regulation of actin filament depolymerization GO:0030835 36 25 1,000 0,01716268 0,12108641 ! negative regulation of actin filament polymerization GO:0030837 36 25 1,000 0,01716268 0,12071611 ! iron ion homeostasis GO:0055072 39 25 1,000 0,01716268 0,12034808 ! regulation of peptide secretion GO:0002791 34 25 1,000 0,01716268 0,11998228 ! regulation of chromosome organization GO:0033044 35 25 1,000 0,01716268 0,1196187 ! negative regulation of lymphocyte activation GO:0051250 37 25 1,000 0,01716268 0,11925731 ! regulation of pH GO:0006885 36 26 1,000 0,01849577 0,12813337 ! negative regulation of protein polymerization GO:0032272 38 26 1,000 0,01849577 0,12774859 ! regulation of actin filament depolymerization GO:0030834 39 27 1,000 0,01987115 0,13683725 ! catechol metabolic process GO:0009712 43 27 1,000 0,01987115 0,13642878 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 37 27 1,000 0,01987115 0,13602274 ! negative regulation of leukocyte activation GO:0002695 39 27 1,000 0,01987115 0,13561911 ! negative regulation of transcription regulator activity GO:0090048 47 27 1,000 0,01987115 0,13521787 GO:0043433|negative regulation of transcription factor activity, ! gene silencing GO:0016458 41 27 1,000 0,01987115 0,134819 ! regulation of peptidase activity GO:0052547 106 72 2,000 0,02043841 0,1382598 ! negative regulation of transport GO:0051051 116 73 2,000 0,02119137 0,14293299 ! regulation of blood pressure GO:0008217 107 73 2,000 0,02119137 0,14251506 ! mitochondrion organization GO:0007005 104 73 2,000 0,02119137 0,14209956 ! phenol metabolic process GO:0018958 44 28 1,000 0,02128805 0,14233288 ! negative regulation of protein complex assembly GO:0031333 42 28 1,000 0,02128805 0,14192032 ! negative regulation of response to external stimulus GO:0032102 37 28 1,000 0,02128805 0,14151015 ! GPI anchor metabolic process GO:0006505 40 28 1,000 0,02128805 0,14110234 ! response to organic cyclic substance GO:0014070 47 28 1,000 0,02128805 0,14069687 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 1,000 0,02128805 0,14029373 ! sterol biosynthetic process GO:0016126 40 28 1,000 0,02128805 0,13989289 ! ensheathment of neurons GO:0007272 43 28 1,000 0,02128805 0,13949433 GO:0008366|axon ensheathment, ! positive regulation of catabolic process GO:0009896 40 28 1,000 0,02128805 0,13909804 ! placenta development GO:0001890 37 28 1,000 0,02128805 0,138704 ! response to nutrient GO:0007584 104 75 2,000 0,02274252 0,14776214 ! response to hydrogen peroxide GO:0042542 42 29 1,000 0,02274572 0,14736666 ! mismatch repair GO:0006298 34 29 1,000 0,02274572 0,14695271 ! regulation of protein import into nucleus GO:0042306 53 29 1,000 0,02274572 0,14654108 ! tissue homeostasis GO:0001894 42 29 1,000 0,02274572 0,14613175 GO:0048871|multicellular organismal homeostasis, ! spindle organization GO:0007051 37 30 1,000 0,02424344 0,15532006 ! hindbrain development GO:0030902 45 30 1,000 0,02424344 0,15488862 ! adult locomotory behavior GO:0008344 47 30 1,000 0,02424344 0,15445956 ! negative regulation of cell activation GO:0050866 44 30 1,000 0,02424344 0,15403288 ! cholesterol metabolic process GO:0008203 109 77 2,000 0,02435398 0,15430893 ! sex differentiation GO:0007548 105 77 2,000 0,02435398 0,15388501 ! glial cell differentiation GO:0010001 55 31 1,000 0,02578045 0,16245217 ! xenobiotic metabolic process GO:0006805 44 31 1,000 0,02578045 0,16200831 ! maintenance of protein location in cell GO:0032507 60 31 1,000 0,02578045 0,16156687 ! positive regulation of gene-specific transcription GO:0043193 47 31 1,000 0,02578045 0,16112783 ! response to mechanical stimulus GO:0009612 43 31 1,000 0,02578045 0,16069117 ! forebrain development GO:0030900 131 80 2,000 0,02688413 0,16711755 ! monovalent inorganic cation homeostasis GO:0055067 45 32 1,000 0,02735605 0,16959278 ! peripheral nervous system development GO:0007422 53 32 1,000 0,02735605 0,16913689 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 1,000 0,02896952 0,17863245 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of DNA metabolic process GO:0051054 54 33 1,000 0,02896952 0,17815482 ! phosphoinositide biosynthetic process GO:0046489 47 33 1,000 0,02896952 0,17767975 ! ear morphogenesis GO:0042471 42 33 1,000 0,02896952 0,17720719 ! female gonad development GO:0008585 49 33 1,000 0,02896952 0,17673715 ! negative regulation of DNA binding GO:0043392 54 33 1,000 0,02896952 0,17626959 ! lipid homeostasis GO:0055088 55 33 1,000 0,02896952 0,1758045 ! regulation of proteolysis GO:0030162 50 33 1,000 0,02896952 0,17534185 ! negative regulation of hydrolase activity GO:0051346 50 33 1,000 0,02896952 0,17488164 ! cytokinesis GO:0000910 52 33 1,000 0,02896952 0,17442383 ! microtubule cytoskeleton organization GO:0000226 120 84 2,000 0,03046795 0,1829668 ! sterol metabolic process GO:0016125 120 84 2,000 0,03046795 0,18249033 ! mRNA catabolic process GO:0006402 48 34 1,000 0,03062016 0,18292563 ! feeding behavior GO:0007631 45 34 1,000 0,03062016 0,18245173 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 1,000 0,03062016 0,18198028 ! cellular response to insulin stimulus GO:0032869 52 34 1,000 0,03062016 0,18151126 ! regulation of membrane potential GO:0042391 128 85 2,000 0,03140131 0,1856633 ! keratinocyte differentiation GO:0030216 47 35 1,000 0,03230727 0,19053004 ! regulation of action potential in neuron GO:0019228 54 35 1,000 0,03230727 0,19004275 ! maintenance of protein location GO:0045185 65 35 1,000 0,03230727 0,18955795 ! protein homooligomerization GO:0051260 52 35 1,000 0,03230727 0,18907562 ! response to reactive oxygen species GO:0000302 55 36 1,000 0,03403016 0,19865322 ! regulation of hormone secretion GO:0046883 48 36 1,000 0,03403016 0,1981503 ! negative regulation of binding GO:0051100 58 36 1,000 0,03403016 0,19764992 ! development of primary female sexual characteristics GO:0046545 52 36 1,000 0,03403016 0,19715206 GO:0046660|female sex differentiation, ! response to xenobiotic stimulus GO:0009410 50 36 1,000 0,03403016 0,19665671 ! anatomical structure homeostasis GO:0060249 136 88 2,000 0,03429073 0,19766585 ! amino acid activation GO:0043038 52 37 1,000 0,03578816 0,20578191 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! leukocyte differentiation GO:0002521 143 90 2,000 0,03629108 0,20815335 ! hormone metabolic process GO:0042445 121 90 2,000 0,03629108 0,20763556 ! gliogenesis GO:0042063 71 38 1,000 0,03758059 0,21447981 ! monocarboxylic acid transport GO:0015718 62 38 1,000 0,03758059 0,21394892 ! regulation of T cell proliferation GO:0042129 58 38 1,000 0,03758059 0,21342065 ! maintenance of location in cell GO:0051651 69 38 1,000 0,03758059 0,21289499 ! regulation of cytoskeleton organization GO:0051493 154 93 2,000 0,03940192 0,22266442 ! polysaccharide metabolic process GO:0005976 129 93 2,000 0,03940192 0,22211868 ! negative regulation of protein complex disassembly GO:0043242 67 39 1,000 0,0394068 0,22160305 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 1,000 0,0394068 0,22106256 ! cell growth GO:0016049 61 39 1,000 0,0394068 0,22052469 ! synapse organization GO:0050808 55 39 1,000 0,0394068 0,21998944 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 0,03968637 0,2210137 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 0,03968637 0,22047985 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 0,03968637 0,21994858 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 0,03968637 0,21941985 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 0,03968637 0,21889367 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,03968637 0,21837 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 0,03968637 0,21784883 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 0,03968637 0,21733014 ! sleep GO:0030431 11 5 0,000 0,03968637 0,21681392 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,03968637 0,21630014 ! nucleotide-sugar transport GO:0015780 8 5 0,000 0,03968637 0,21578879 ! regulation of interferon-beta production GO:0032648 5 5 0,000 0,03968637 0,21527986 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 0,03968637 0,21477332 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 0,03968637 0,21426915 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 0,03968637 0,21376735 ! tongue development GO:0043586 6 5 0,000 0,03968637 0,21326789 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 0,03968637 0,21277077 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,03968637 0,21227595 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 0,03968637 0,21178343 ! cobalt ion transport GO:0006824 9 5 0,000 0,03968637 0,21129319 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 0,03968637 0,21080522 ! SMAD protein complex assembly GO:0007183 9 5 0,000 0,03968637 0,21031949 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 0,03968637 0,209836 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 0,03968637 0,20935472 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 0,03968637 0,20887565 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 0,03968637 0,20839876 ! embryonic camera-type eye development GO:0031076 8 5 0,000 0,03968637 0,20792405 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 0,03968637 0,2074515 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 0,03968637 0,20698109 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,03968637 0,2065128 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,03968637 0,20604663 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,03968637 0,20558257 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 0,03968637 0,20512058 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,03968637 0,20466067 ! malate metabolic process GO:0006108 7 5 0,000 0,03968637 0,20420282 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 0,03968637 0,20374701 ! behavioral response to pain GO:0048266 7 5 0,000 0,03968637 0,20329323 ! clathrin coat assembly GO:0048268 11 5 0,000 0,03968637 0,20284146 ! phototransduction, visible light GO:0007603 6 5 0,000 0,03968637 0,20239171 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,03968637 0,20194394 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 0,03968637 0,20149814 ! mating behavior GO:0007617 6 5 0,000 0,03968637 0,20105432 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,03968637 0,20061244 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 0,03968637 0,2001725 ! rhythmic behavior GO:0007622 12 5 0,000 0,03968637 0,19973448 ! copulation GO:0007620 7 5 0,000 0,03968637 0,19929838 ! protein maturation by protein folding GO:0022417 12 5 0,000 0,03968637 0,19886418 ! embryonic hemopoiesis GO:0035162 10 5 0,000 0,03968637 0,19843187 ! regulation of potassium ion transport GO:0043266 9 5 0,000 0,03968637 0,19800143 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 0,03968637 0,19757286 ! apoptotic cell clearance GO:0043277 13 5 0,000 0,03968637 0,19714613 ! lipoprotein particle clearance GO:0034381 9 5 0,000 0,03968637 0,19672125 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,03968637 0,19629819 ! response to protozoan GO:0001562 9 5 0,000 0,03968637 0,19587695 ! positive regulation of glycolysis GO:0045821 11 5 0,000 0,03968637 0,19545751 ! lymph vessel development GO:0001945 7 5 0,000 0,03968637 0,19503987 ! endochondral ossification GO:0001958 12 5 0,000 0,03968637 0,19462401 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 0,03968637 0,19420991 ! parathyroid gland development GO:0060017 8 5 0,000 0,03968637 0,19379758 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 0,03968637 0,19338699 ! anagen GO:0042640 6 5 0,000 0,03968637 0,19297814 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 0,03968637 0,19257101 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 0,03968637 0,1921656 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! nuclear migration GO:0007097 10 5 0,000 0,03968637 0,19176189 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 0,03968637 0,19135987 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 0,03968637 0,19095954 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 0,03968637 0,19056087 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 0,03968637 0,19016387 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 0,03968637 0,18976852 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 0,03968637 0,18937481 ! cardiac muscle fiber development GO:0048739 7 5 0,000 0,03968637 0,18898273 ! neutrophil mediated immunity GO:0002446 6 5 0,000 0,03968637 0,18859227 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 0,03968637 0,18820342 ! ovulation GO:0030728 6 5 0,000 0,03968637 0,18781617 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 0,03968637 0,18743051 GO:0033135|regulation of peptidyl-serine phosphorylation, ! microvillus organization GO:0032528 7 5 0,000 0,03968637 0,18704643 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 8 5 0,000 0,03968637 0,18666392 ! response to pH GO:0009268 9 5 0,000 0,03968637 0,18628298 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 0,03968637 0,18590358 ! proline biosynthetic process GO:0006561 6 5 0,000 0,03968637 0,18552573 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,03968637 0,18514941 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 0,03968637 0,18477461 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,03968637 0,18440133 ! polyol catabolic process GO:0046174 7 5 0,000 0,03968637 0,18402955 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,03968637 0,18365927 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,03968637 0,18329048 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,03968637 0,18292316 ! sister chromatid cohesion GO:0007062 9 5 0,000 0,03968637 0,18255732 ! nerve growth factor processing GO:0032455 7 5 0,000 0,03968637 0,18219293 ! urea metabolic process GO:0019627 6 5 0,000 0,03968637 0,18183 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 0,03968637 0,18146851 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 0,000 0,03968637 0,18110845 ! neutrophil activation GO:0042119 5 5 0,000 0,03968637 0,18074982 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 0,03968637 0,18039261 GO:0060177|regulation of angiotensin metabolic process, ! response to food GO:0032094 5 5 0,000 0,03968637 0,1800368 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 0,03968637 0,1796824 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,03968637 0,17932939 ! paraxial mesoderm development GO:0048339 9 5 0,000 0,03968637 0,17897776 ! forebrain neuron development GO:0021884 7 5 0,000 0,03968637 0,17862751 ! melanosome organization GO:0032438 7 5 0,000 0,03968637 0,17827863 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 0,03968637 0,17793111 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,03968637 0,17758494 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 0,03968637 0,17724011 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,03968637 0,17689663 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 14 5 0,000 0,03968637 0,17655447 ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 0,03968637 0,17621363 ! nucleoside transport GO:0015858 6 5 0,000 0,03968637 0,1758741 ! nucleoside salvage GO:0043174 7 5 0,000 0,03968637 0,17553588 GO:0006166|purine ribonucleoside salvage, ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,03968637 0,17519896 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 0,03968637 0,17486333 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 0,03968637 0,17452898 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,03968637 0,17419591 ! depyrimidination GO:0045008 8 5 0,000 0,03968637 0,17386411 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 0,03968637 0,17353357 ! 5S class rRNA transcription GO:0042791 8 5 0,000 0,03968637 0,17320429 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 0,03968637 0,17287625 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,03968637 0,17254945 ! neuronal ion channel clustering GO:0045161 7 5 0,000 0,03968637 0,17222388 ! sodium ion homeostasis GO:0055078 6 5 0,000 0,03968637 0,17189955 ! homeostasis of number of cells within a tissue GO:0048873 9 5 0,000 0,03968637 0,17157643 ! negative regulation of gliogenesis GO:0014014 16 5 0,000 0,03968637 0,17125452 GO:0045686|negative regulation of glial cell differentiation, ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 0,03968637 0,17093382 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 0,03968637 0,17061432 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 0,03968637 0,17029601 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 0,03968637 0,16997888 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 0,03968637 0,16966293 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 0,03968637 0,16934816 ! regulation of dendrite development GO:0050773 12 5 0,000 0,03968637 0,16903455 ! peptidyl-arginine modification GO:0018195 7 5 0,000 0,03968637 0,16872211 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,03968637 0,16841081 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 0,03968637 0,16810066 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 0,03968637 0,16779165 ! regulation of dopamine secretion GO:0014059 12 5 0,000 0,03968637 0,16748378 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 0,03968637 0,16717703 ! cranial nerve morphogenesis GO:0021602 6 5 0,000 0,03968637 0,16687141 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 0,03968637 0,1665669 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,03968637 0,1662635 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 0,03968637 0,1659612 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,03968637 0,16566 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 0,03968637 0,16535989 ! positive regulation of Rho GTPase activity GO:0032321 9 5 0,000 0,03968637 0,16506087 ! neural tube patterning GO:0021532 6 5 0,000 0,03968637 0,16476292 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 0,03968637 0,16446605 ! histone demethylation GO:0016577 9 5 0,000 0,03968637 0,16417025 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,03968637 0,16387551 ! positive regulation of chemokine production GO:0032722 7 5 0,000 0,03968637 0,16358183 ! enteric nervous system development GO:0048484 8 5 0,000 0,03968637 0,16328919 ! establishment of planar polarity GO:0001736 6 5 0,000 0,03968637 0,16299761 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 0,03968637 0,16270706 ! muscle cell proliferation GO:0033002 8 5 0,000 0,03968637 0,16241754 ! transcription termination GO:0006353 8 5 0,000 0,03968637 0,16212906 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 0,03968637 0,16184159 ! positive regulation of pseudopodium assembly GO:0031274 13 5 0,000 0,03968637 0,16155515 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 5 5 0,000 0,03968637 0,16126972 ! regulation of respiratory burst GO:0060263 8 5 0,000 0,03968637 0,16098529 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 0,03968637 0,16070186 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,03968637 0,16041944 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,03968637 0,160138 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 0,03968637 0,15985755 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 0,03968637 0,15957808 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 0,03968637 0,15929958 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 0,03968637 0,15902205 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,03968637 0,15874549 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 0,03968637 0,15846989 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 0,03968637 0,15819525 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 0,03968637 0,15792156 ! triglyceride catabolic process GO:0019433 6 5 0,000 0,03968637 0,15764881 ! glial cell migration GO:0008347 10 5 0,000 0,03968637 0,157377 ! determination of adult lifespan GO:0008340 8 5 0,000 0,03968637 0,15710613 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 0,03968637 0,15683618 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,03968637 0,15656717 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,03968637 0,15629907 ! somatic stem cell maintenance GO:0035019 13 5 0,000 0,03968637 0,1560319 ! cerebellar cortex formation GO:0021697 6 5 0,000 0,03968637 0,15576563 ! neural plate development GO:0001840 6 5 0,000 0,03968637 0,15550027 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 0,000 0,03968637 0,15523581 ! regulation of sensory perception GO:0051931 6 5 0,000 0,03968637 0,15497226 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 0,03968637 0,15470959 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 0,03968637 0,15444782 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 10 5 0,000 0,03968637 0,15418692 ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 0,03968637 0,15392691 ! sensory cilium assembly GO:0035058 6 5 0,000 0,03968637 0,15366778 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 0,03968637 0,15340951 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,03968637 0,15315211 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 0,03968637 0,15289558 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 0,03968637 0,1526399 GO:0022011|myelination in the peripheral nervous system, ! protein amino acid prenylation GO:0018346 9 5 0,000 0,03968637 0,15238507 ! organ regeneration GO:0031100 7 5 0,000 0,03968637 0,1521311 ! NAD biosynthetic process GO:0009435 7 5 0,000 0,03968637 0,15187797 ! carnitine metabolic process GO:0009437 5 5 0,000 0,03968637 0,15162568 GO:0006577|betaine metabolic process, ! positive regulation of microtubule polymerization GO:0031116 9 5 0,000 0,03968637 0,15137423 ! cellular anion homeostasis GO:0030002 6 5 0,000 0,03968637 0,15112361 GO:0055081|anion homeostasis, ! response to oxidative stress GO:0006979 141 94 2,000 0,0404681 0,15384566 ! regulation of actin filament polymerization GO:0030833 59 40 1,000 0,04126614 0,15662065 ! response to calcium ion GO:0051592 58 40 1,000 0,04126614 0,15636263 ! detection of stimulus involved in sensory perception GO:0050906 50 40 1,000 0,04126614 0,15610545 ! T cell differentiation GO:0030217 65 40 1,000 0,04126614 0,15584912 ! B cell differentiation GO:0030183 62 40 1,000 0,04126614 0,15559363 ! epidermal cell differentiation GO:0009913 53 40 1,000 0,04126614 0,15533898 ! angiogenesis GO:0001525 149 95 2,000 0,04154881 0,15614747 ! protein amino acid lipidation GO:0006497 62 41 1,000 0,04315795 0,16193031 ! endosome transport GO:0016197 71 41 1,000 0,04315795 0,16166658 ! regulation of T cell differentiation GO:0045580 59 41 1,000 0,04315795 0,16140371 ! mitochondrial transport GO:0006839 60 42 1,000 0,0450816 0,16832415 ! cellular component disassembly GO:0022411 64 42 1,000 0,0450816 0,16805134 ! branching morphogenesis of a tube GO:0048754 72 42 1,000 0,0450816 0,16777941 ! regulation of gene expression, epigenetic GO:0040029 72 42 1,000 0,0450816 0,16750836 ! regulation of cell shape GO:0008360 78 42 1,000 0,0450816 0,16723819 ! extracellular structure organization GO:0043062 156 99 2,000 0,04601587 0,17042914 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 1,000 0,04703646 0,17392904 ! regulation of gene-specific transcription GO:0032583 69 43 1,000 0,04703646 0,17364986 ! Ras protein signal transduction GO:0007265 162 100 2,000 0,0471684 0,17385789 ! tRNA transcription GO:0009304 11 6 0,000 0,04743394 0,1745569 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 0,04743394 0,17427805 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 8 6 0,000 0,04743394 0,1740001 ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 0,04743394 0,17372303 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,04743394 0,17344684 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 0,04743394 0,17317153 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 0,04743394 0,17289709 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 0,04743394 0,17262352 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 0,04743394 0,17235081 ! positive regulation of axon extension GO:0045773 8 6 0,000 0,04743394 0,17207896 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 0,04743394 0,17180797 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 0,04743394 0,17153783 ! forebrain neuron differentiation GO:0021879 9 6 0,000 0,04743394 0,17126854 GO:0021872|generation of neurons in the forebrain, ! regulation of lipid catabolic process GO:0050994 9 6 0,000 0,04743394 0,1710001 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 0,04743394 0,17073249 GO:0046463|acylglycerol biosynthetic process, ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 0,04743394 0,17046572 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 0,04743394 0,17019979 ! neuron adhesion GO:0007158 9 6 0,000 0,04743394 0,16993468 ! N-terminal protein amino acid acetylation GO:0006474 7 6 0,000 0,04743394 0,16967039 ! establishment of tissue polarity GO:0007164 7 6 0,000 0,04743394 0,16940693 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 0,04743394 0,16914428 ! signal peptide processing GO:0006465 8 6 0,000 0,04743394 0,16888245 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 0,04743394 0,16862143 ! mRNA stabilization GO:0048255 15 6 0,000 0,04743394 0,16836121 GO:0043489|RNA stabilization, ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 0,04743394 0,16810179 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 0,04743394 0,16784317 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 0,04743394 0,16758535 ! opsonization GO:0008228 8 6 0,000 0,04743394 0,16732832 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 0,04743394 0,16707207 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 0,04743394 0,16681661 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 0,04743394 0,16656193 ! protein amino acid dealkylation GO:0008214 11 6 0,000 0,04743394 0,16630802 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 0,04743394 0,16605489 ! photoreceptor cell development GO:0042461 10 6 0,000 0,04743394 0,16580253 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 0,04743394 0,16555093 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 0,04743394 0,16530009 ! mechanosensory behavior GO:0007638 8 6 0,000 0,04743394 0,16505002 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 0,04743394 0,1648007 ! negative regulation of endocytosis GO:0045806 8 6 0,000 0,04743394 0,16455213 ! response to interferon-gamma GO:0034341 12 6 0,000 0,04743394 0,16430431 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 0,04743394 0,16405724 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 0,04743394 0,1638109 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,04743394 0,16356531 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 0,04743394 0,16332045 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 0,04743394 0,16307633 ! cGMP-mediated signaling GO:0019934 10 6 0,000 0,04743394 0,16283293 ! activation of MAPKKK activity GO:0000185 10 6 0,000 0,04743394 0,16259026 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 0,04743394 0,16234831 ! thymic T cell selection GO:0045061 12 6 0,000 0,04743394 0,16210708 ! protein lipoylation GO:0009249 10 6 0,000 0,04743394 0,16186656 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 0,04743394 0,16162676 ! pigment granule organization GO:0048753 11 6 0,000 0,04743394 0,16138767 ! drug transport GO:0015893 6 6 0,000 0,04743394 0,16114928 ! cysteine metabolic process GO:0006534 7 6 0,000 0,04743394 0,1609116 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 0,04743394 0,16067461 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,04743394 0,16043833 ! histidine metabolic process GO:0006547 6 6 0,000 0,04743394 0,16020273 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 0,04743394 0,15996783 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 0,04743394 0,15973362 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 0,000 0,04743394 0,15950009 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! glycine catabolic process GO:0006546 9 6 0,000 0,04743394 0,15926724 ! adenohypophysis development GO:0021984 10 6 0,000 0,04743394 0,15903508 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 0,04743394 0,15880358 ! hyperosmotic response GO:0006972 8 6 0,000 0,04743394 0,15857276 ! microtubule nucleation GO:0007020 10 6 0,000 0,04743394 0,15834262 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 0,04743394 0,15811313 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 0,04743394 0,15788432 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 0,04743394 0,15765616 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 0,04743394 0,15742866 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 0,04743394 0,15720182 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 0,000 0,04743394 0,15697563 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 0,04743394 0,15675009 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 0,04743394 0,1565252 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 0,04743394 0,15630095 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 0,04743394 0,15607734 ! glycerol ether catabolic process GO:0044269 8 6 0,000 0,04743394 0,15585437 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 0,04743394 0,15563204 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,04743394 0,15541034 ! neuron apoptosis GO:0051402 8 6 0,000 0,04743394 0,15518928 ! organic alcohol transport GO:0015850 9 6 0,000 0,04743394 0,15496884 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 0,000 0,04743394 0,15474902 ! T cell mediated immunity GO:0002456 12 6 0,000 0,04743394 0,15452983 ! male sex determination GO:0030238 9 6 0,000 0,04743394 0,15431126 ! carnitine transport GO:0015879 8 6 0,000 0,04743394 0,15409331 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 0,04743394 0,15387597 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 0,04743394 0,15365924 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,04743394 0,15344313 ! positive regulation of exocytosis GO:0045921 6 6 0,000 0,04743394 0,15322762 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 0,04743394 0,15301271 ! parturition GO:0007567 12 6 0,000 0,04743394 0,15279841 ! negative regulation of translational initiation GO:0045947 7 6 0,000 0,04743394 0,1525847 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 0,04743394 0,1523716 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 0,04743394 0,15215908 ! spindle checkpoint GO:0031577 14 6 0,000 0,04743394 0,15194716 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 0,04743394 0,15173583 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 0,04743394 0,15152509 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 0,04743394 0,15131493 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 0,04743394 0,15110535 ! macrophage differentiation GO:0030225 10 6 0,000 0,04743394 0,15089635 ! astrocyte development GO:0014002 14 6 0,000 0,04743394 0,15068793 ! hyaluronan metabolic process GO:0030212 6 6 0,000 0,04743394 0,15048009 ! purine base biosynthetic process GO:0009113 14 6 0,000 0,04743394 0,15027281 ! interaction with symbiont GO:0051702 8 6 0,000 0,04743394 0,15006611 ! anterograde axon cargo transport GO:0008089 8 6 0,000 0,04743394 0,14985998 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,04743394 0,14965441 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 0,04743394 0,1494494 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 0,04743394 0,14924496 ! response to copper ion GO:0046688 9 6 0,000 0,04743394 0,14904107 ! response to exogenous dsRNA GO:0043330 8 6 0,000 0,04743394 0,14883774 ! enucleate erythrocyte differentiation GO:0043353 9 6 0,000 0,04743394 0,14863496 ! establishment of melanosome localization GO:0032401 9 6 0,000 0,04743394 0,14843274 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,04743394 0,14823106 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,04743394 0,14802994 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 0,04743394 0,14782935 ! nucleoside catabolic process GO:0009164 6 6 0,000 0,04743394 0,14762931 ! gas homeostasis GO:0033483 11 6 0,000 0,04743394 0,14742981 ! hair follicle maturation GO:0048820 7 6 0,000 0,04743394 0,14723085 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 0,04743394 0,14703243 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 0,04743394 0,14683454 ! Schwann cell development GO:0014044 14 6 0,000 0,04743394 0,14663718 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 0,04743394 0,14644035 ! dendrite morphogenesis GO:0048813 9 6 0,000 0,04743394 0,14624405 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,04743394 0,14604828 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 0,04743394 0,14585302 ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 0,04743394 0,14565829 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 0,04743394 0,14546408 ! histone ubiquitination GO:0016574 7 6 0,000 0,04743394 0,14527039 ! regulation of meiosis GO:0040020 10 6 0,000 0,04743394 0,14507721 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 0,04743394 0,14488454 GO:0000085|G2 phase of mitotic cell cycle, ! regulation of cell division GO:0051302 8 6 0,000 0,04743394 0,14469239 ! regulation of mast cell activation GO:0033003 6 6 0,000 0,04743394 0,14450074 ! membrane to membrane docking GO:0022614 12 6 0,000 0,04743394 0,14430961 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 0,04743394 0,14411897 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 0,04743394 0,14392884 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 0,04743394 0,14373921 ! receptor internalization GO:0031623 9 6 0,000 0,04743394 0,14355008 ! neutrophil homeostasis GO:0001780 6 6 0,000 0,04743394 0,14336145 ! coenzyme A metabolic process GO:0015936 9 6 0,000 0,04743394 0,14317331 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,04743394 0,14298566 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 0,000 0,04743394 0,14279851 ! protein deubiquitination GO:0016579 8 6 0,000 0,04743394 0,14261185 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 0,04743394 0,14242567 ! peptidyl-histidine modification GO:0018202 9 6 0,000 0,04743394 0,14223998 ! axonal fasciculation GO:0007413 9 6 0,000 0,04743394 0,14205477 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 0,04743394 0,14187004 ! thiamin metabolic process GO:0006772 6 6 0,000 0,04743394 0,1416858 ! midbrain development GO:0030901 6 6 0,000 0,04743394 0,14150203 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 0,04743394 0,14131873 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,04743394 0,14113591 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 0,04743394 0,14095357 ! progesterone metabolic process GO:0042448 8 6 0,000 0,04743394 0,14077169 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 0,04743394 0,14059029 ! glycolipid catabolic process GO:0019377 13 6 0,000 0,04743394 0,14040935 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 0,04743394 0,14022887 ! positive regulation of glucose import GO:0046326 6 6 0,000 0,04743394 0,14004886 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 0,04743394 0,13986931 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 0,04743394 0,13969022 ! pigment granule transport GO:0051904 12 6 0,000 0,04743394 0,13951159 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 0,04743394 0,13933341 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 0,04743394 0,13915569 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,04743394 0,13897842 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 0,04743394 0,13880161 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 0,04743394 0,13862524 ! negative regulation of B cell activation GO:0050869 9 6 0,000 0,04743394 0,13844932 ! protein prenylation GO:0018342 10 6 0,000 0,04743394 0,13827384 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,04743394 0,13809881 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 0,000 0,04743394 0,13792423 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 0,000 0,04743394 0,13775008 ! regulation of microtubule polymerization GO:0031113 11 6 0,000 0,04743394 0,13757637 ! positive regulation of coagulation GO:0050820 11 6 0,000 0,04743394 0,1374031 ! regulation of action potential GO:0001508 71 44 1,000 0,04902192 0,14182442 ! detection of abiotic stimulus GO:0009582 58 44 1,000 0,04902192 0,14164625 ! regulation of mast cell proliferation GO:0070666 64 44 1,000 0,04902192 0,14146853 ! RNA catabolic process GO:0006401 64 45 1,000 0,05103735 0,14710014 ! lipoprotein biosynthetic process GO:0042158 67 45 1,000 0,05103735 0,14691604 ! regulation of protein complex disassembly GO:0043244 77 46 1,000 0,05308216 0,15261122 ! histone modification GO:0016570 68 46 1,000 0,05308216 0,1524207 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 0,05511944 0,15807321 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 0,05511944 0,15787636 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 0,05511944 0,15767999 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 0,05511944 0,15748412 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,05511944 0,15728873 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 0,05511944 0,15709382 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,05511944 0,1568994 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 0,05511944 0,15670546 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 0,05511944 0,15651199 ! reproductive behavior GO:0019098 12 7 0,000 0,05511944 0,15631901 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 0,05511944 0,1561265 ! regulation of lipid kinase activity GO:0043550 12 7 0,000 0,05511944 0,15593446 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 0,05511944 0,15574289 ! regulation of smooth muscle cell migration GO:0014910 19 7 0,000 0,05511944 0,1555518 ! oligopeptide transport GO:0006857 11 7 0,000 0,05511944 0,15536117 ! protein amino acid sulfation GO:0006477 9 7 0,000 0,05511944 0,15517101 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 0,05511944 0,15498131 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! negative regulation of JAK-STAT cascade GO:0046426 15 7 0,000 0,05511944 0,15479208 ! RNA methylation GO:0001510 11 7 0,000 0,05511944 0,15460331 ! pericardium development GO:0060039 8 7 0,000 0,05511944 0,154415 ! macrophage chemotaxis GO:0048246 10 7 0,000 0,05511944 0,15422715 ! fibril organization GO:0043206 13 7 0,000 0,05511944 0,15403975 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 0,05511944 0,15385281 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 0,05511944 0,15366632 ! cerebral cortex cell migration GO:0021795 11 7 0,000 0,05511944 0,15348028 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,05511944 0,1532947 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,05511944 0,15310956 ! estrogen metabolic process GO:0008210 14 7 0,000 0,05511944 0,15292487 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 0,05511944 0,15274062 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 0,05511944 0,15255682 ! chemosensory behavior GO:0007635 9 7 0,000 0,05511944 0,15237345 ! microtubule bundle formation GO:0001578 8 7 0,000 0,05511944 0,15219053 ! T-helper 1 type immune response GO:0042088 11 7 0,000 0,05511944 0,15200805 ! leukocyte degranulation GO:0043299 10 7 0,000 0,05511944 0,15182601 ! bile acid and bile salt transport GO:0015721 9 7 0,000 0,05511944 0,1516444 ! reflex GO:0060004 12 7 0,000 0,05511944 0,15146322 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,05511944 0,15128248 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 0,05511944 0,15110216 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,05511944 0,15092228 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 0,05511944 0,15074282 ! glycerolipid catabolic process GO:0046503 9 7 0,000 0,05511944 0,15056379 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,05511944 0,15038519 ! spinal cord patterning GO:0021511 7 7 0,000 0,05511944 0,15020701 ! hemoglobin metabolic process GO:0020027 10 7 0,000 0,05511944 0,15002925 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 0,05511944 0,14985191 ! adrenal gland development GO:0030325 17 7 0,000 0,05511944 0,14967499 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 0,05511944 0,14949848 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 0,05511944 0,1493224 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 0,05511944 0,14914672 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 0,05511944 0,14897146 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 0,05511944 0,14879661 ! endosome organization GO:0007032 10 7 0,000 0,05511944 0,14862217 ! thyroid hormone generation GO:0006590 11 7 0,000 0,05511944 0,14844814 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 0,05511944 0,14827452 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 0,05511944 0,1481013 ! regulation of pigmentation during development GO:0048070 15 7 0,000 0,05511944 0,14792849 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,05511944 0,14775608 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 0,05511944 0,14758407 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,05511944 0,14741246 ! galactose metabolic process GO:0006012 10 7 0,000 0,05511944 0,14724125 ! vesicle fusion GO:0006906 15 7 0,000 0,05511944 0,14707043 ! intracellular pH reduction GO:0051452 10 7 0,000 0,05511944 0,14690002 GO:0045851|pH reduction, ! organ growth GO:0035265 11 7 0,000 0,05511944 0,14672999 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 0,05511944 0,14656036 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 0,000 0,05511944 0,14639113 ! Rac protein signal transduction GO:0016601 7 7 0,000 0,05511944 0,14622228 ! retinol metabolic process GO:0042572 9 7 0,000 0,05511944 0,14605382 ! behavioral fear response GO:0001662 13 7 0,000 0,05511944 0,14588575 GO:0002209|behavioral defense response, ! negative regulation of muscle contraction GO:0045932 12 7 0,000 0,05511944 0,14571806 ! rRNA modification GO:0000154 12 7 0,000 0,05511944 0,14555076 ! protein heterooligomerization GO:0051291 10 7 0,000 0,05511944 0,14538385 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,05511944 0,14521731 ! response to UV-B GO:0010224 11 7 0,000 0,05511944 0,14505116 ! protein retention in ER lumen GO:0006621 12 7 0,000 0,05511944 0,14488539 ! intermediate filament organization GO:0045109 11 7 0,000 0,05511944 0,14471999 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 0,05511944 0,14455498 ! cardiac muscle cell development GO:0055013 9 7 0,000 0,05511944 0,14439034 ! fibrinolysis GO:0042730 9 7 0,000 0,05511944 0,14422607 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 0,000 0,05511944 0,14406218 ! regulation of circadian rhythm GO:0042752 11 7 0,000 0,05511944 0,14389865 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 0,05511944 0,1437355 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 0,05511944 0,14357272 ! response to tropane GO:0014073 13 7 0,000 0,05511944 0,14341031 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! melanosome localization GO:0032400 10 7 0,000 0,05511944 0,14324826 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 0,05511944 0,14308659 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 0,05511944 0,14292527 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 0,05511944 0,14276432 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 0,05511944 0,14260373 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 0,05511944 0,1424435 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 0,05511944 0,14228363 ! mast cell activation GO:0045576 9 7 0,000 0,05511944 0,14212412 ! multicellular organismal aging GO:0010259 11 7 0,000 0,05511944 0,14196497 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 0,05511944 0,14180617 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 0,05511944 0,14164773 ! positive regulation of monooxygenase activity GO:0032770 11 7 0,000 0,05511944 0,14148964 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 0,05511944 0,1413319 ! establishment of nucleus localization GO:0040023 13 7 0,000 0,05511944 0,14117451 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 0,05511944 0,14101748 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 0,05511944 0,14086079 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 0,05511944 0,14070446 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 0,05511944 0,14054846 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 0,05511944 0,14039282 ! neuroblast proliferation GO:0007405 13 7 0,000 0,05511944 0,14023752 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 0,05511944 0,14008256 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 0,000 0,05511944 0,13992794 ! peptidyl-threonine modification GO:0018210 18 7 0,000 0,05511944 0,13977367 ! diuresis GO:0030146 12 7 0,000 0,05511944 0,13961973 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 0,05511944 0,13946613 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of epidermis development GO:0045684 11 7 0,000 0,05511944 0,13931287 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,05511944 0,13915995 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 0,05511944 0,13900736 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,05511944 0,13885511 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,05511944 0,13870319 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,05511944 0,1385516 ! regulation of synaptogenesis GO:0051963 10 7 0,000 0,05511944 0,13840034 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 0,05511944 0,13824942 ! dopamine biosynthetic process GO:0042416 15 7 0,000 0,05511944 0,13809882 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 0,05511944 0,13794855 ! lymph node development GO:0048535 9 7 0,000 0,05511944 0,1377986 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 0,05511944 0,13764898 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 0,05511944 0,13749969 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,05511944 0,13735072 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 0,05511944 0,13720207 ! endosome to lysosome transport GO:0008333 10 7 0,000 0,05511944 0,13705375 ! ATP catabolic process GO:0006200 10 7 0,000 0,05511944 0,13690574 ! establishment of pigment granule localization GO:0051905 13 7 0,000 0,05511944 0,13675805 ! trophectodermal cell differentiation GO:0001829 8 7 0,000 0,05511944 0,13661068 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 0,05511944 0,13646363 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 0,05511944 0,1363169 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 0,05511944 0,13617048 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 0,05511944 0,13602437 ! muscle adaptation GO:0043500 12 7 0,000 0,05511944 0,13587858 ! amino sugar catabolic process GO:0046348 9 7 0,000 0,05511944 0,1357331 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 0,05511944 0,13558793 ! retina homeostasis GO:0001895 9 7 0,000 0,05511944 0,13544307 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 0,05511944 0,13529852 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 0,05511944 0,13515428 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 0,05511944 0,13501035 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 0,05511944 0,13486672 ! behavioral response to nicotine GO:0035095 11 7 0,000 0,05511944 0,13472339 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 0,05511944 0,13458038 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,05511944 0,13443766 ! response to estrogen stimulus GO:0043627 74 47 1,000 0,05515575 0,13438371 ! negative regulation of immune system process GO:0002683 73 47 1,000 0,05515575 0,13424151 ! regulation of leukocyte proliferation GO:0070663 71 47 1,000 0,05515575 0,1340996 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of neuron apoptosis GO:0043523 77 47 1,000 0,05515575 0,133958 ! regulation of protein polymerization GO:0032271 71 47 1,000 0,05515575 0,13381669 ! immunoglobulin mediated immune response GO:0016064 66 48 1,000 0,05725752 0,13876955 GO:0019724|B cell mediated immunity, ! regulation of lymphocyte differentiation GO:0045619 69 48 1,000 0,05725752 0,13862348 ! regulation of angiogenesis GO:0045765 94 49 1,000 0,0593869 0,14362762 ! morphogenesis of a branching structure GO:0001763 86 49 1,000 0,0593869 0,14347676 ! germ cell development GO:0007281 68 49 1,000 0,0593869 0,1433262 ! maintenance of location GO:0051235 84 49 1,000 0,0593869 0,14317597 ! ear development GO:0043583 72 50 1,000 0,06154331 0,14821949 ! skeletal muscle fiber development GO:0048741 73 50 1,000 0,06154331 0,14806444 ! membrane fusion GO:0006944 80 50 1,000 0,06154331 0,14790973 ! negative regulation of cytoskeleton organization GO:0051494 84 50 1,000 0,06154331 0,14775533 ! regulation of multicellular organism growth GO:0040014 65 50 1,000 0,06154331 0,14760126 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 0,06274337 0,15032266 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,06274337 0,15016623 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 0,000 0,06274337 0,15001014 ! axon extension GO:0048675 11 8 0,000 0,06274337 0,14985436 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 0,000 0,06274337 0,14969891 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 0,06274337 0,14954378 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 0,000 0,06274337 0,14938898 GO:0046579|positive regulation of Ras protein signal transduction, ! associative learning GO:0008306 15 8 0,000 0,06274337 0,14923449 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,06274337 0,14908032 ! cell proliferation in forebrain GO:0021846 10 8 0,000 0,06274337 0,14892647 ! positive regulation of B cell proliferation GO:0030890 11 8 0,000 0,06274337 0,14877294 ! phosphate transport GO:0006817 10 8 0,000 0,06274337 0,14861972 ! N-glycan processing GO:0006491 12 8 0,000 0,06274337 0,14846682 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,06274337 0,14831424 ! UTP metabolic process GO:0046051 8 8 0,000 0,06274337 0,14816196 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 0,06274337 0,14801 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 0,06274337 0,14785835 GO:0046457|prostanoid biosynthetic process, ! induction of positive chemotaxis GO:0050930 14 8 0,000 0,06274337 0,14770701 ! succinate metabolic process GO:0006105 14 8 0,000 0,06274337 0,14755598 ! smoothened signaling pathway GO:0007224 8 8 0,000 0,06274337 0,14740526 ! keratinocyte proliferation GO:0043616 12 8 0,000 0,06274337 0,14725485 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,06274337 0,14710474 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 0,06274337 0,14695494 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,06274337 0,14680544 ! ganglioside metabolic process GO:0001573 15 8 0,000 0,06274337 0,14665625 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 0,000 0,06274337 0,14650736 ! pseudouridine synthesis GO:0001522 9 8 0,000 0,06274337 0,14635877 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,06274337 0,14621049 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,06274337 0,1460625 ! endothelial cell differentiation GO:0045446 14 8 0,000 0,06274337 0,14591481 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,06274337 0,14576743 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 0,000 0,06274337 0,14562033 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 0,000 0,06274337 0,14547354 ! astrocyte differentiation GO:0048708 16 8 0,000 0,06274337 0,14532704 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 0,06274337 0,14518084 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,06274337 0,14503493 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,06274337 0,14488931 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 0,06274337 0,14474398 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,06274337 0,14459895 ! melanin metabolic process GO:0006582 12 8 0,000 0,06274337 0,14445421 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 0,06274337 0,14430975 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,06274337 0,14416559 ! positive regulation of endothelial cell migration GO:0010595 18 8 0,000 0,06274337 0,14402171 ! macrophage activation GO:0042116 12 8 0,000 0,06274337 0,14387812 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,06274337 0,14373481 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,06274337 0,14359179 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 0,06274337 0,14344906 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,06274337 0,1433066 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 0,06274337 0,14316444 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 0,06274337 0,14302255 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 0,06274337 0,14288094 ! ruffle organization GO:0031529 11 8 0,000 0,06274337 0,14273962 ! osteoblast development GO:0002076 13 8 0,000 0,06274337 0,14259857 ! lens development in camera-type eye GO:0002088 10 8 0,000 0,06274337 0,1424578 ! positive regulation of vasodilation GO:0045909 12 8 0,000 0,06274337 0,14231731 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,06274337 0,14217709 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 0,06274337 0,14203716 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 0,06274337 0,14189749 ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 0,06274337 0,14175811 ! Schwann cell differentiation GO:0014037 17 8 0,000 0,06274337 0,14161899 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,06274337 0,14148015 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 0,06274337 0,14134158 ! regulation of gliogenesis GO:0014013 20 8 0,000 0,06274337 0,14120328 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 20 8 0,000 0,06274337 0,14106525 ! oligodendrocyte development GO:0014003 8 8 0,000 0,06274337 0,14092749 ! segment specification GO:0007379 10 8 0,000 0,06274337 0,14079 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 0,000 0,06274337 0,14065278 ! cellular extravasation GO:0045123 11 8 0,000 0,06274337 0,14051582 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 0,06274337 0,14037914 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 0,06274337 0,14024271 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 0,06274337 0,14010655 ! snRNA metabolic process GO:0016073 10 8 0,000 0,06274337 0,13997066 GO:0016180|snRNA processing, ! regulation of interleukin-4 production GO:0032673 16 8 0,000 0,06274337 0,13983503 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,06274337 0,13969966 ! regulation of mitochondrial membrane potential GO:0051881 11 8 0,000 0,06274337 0,13956456 ! nucleosome disassembly GO:0006337 12 8 0,000 0,06274337 0,13942971 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 0,06274337 0,13929513 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of Ras GTPase activity GO:0032320 20 8 0,000 0,06274337 0,1391608 ! protein import into peroxisome matrix GO:0016558 14 8 0,000 0,06274337 0,13902674 ! icosanoid secretion GO:0032309 12 8 0,000 0,06274337 0,13889293 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 11 8 0,000 0,06274337 0,13875938 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,06274337 0,13862608 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 0,06274337 0,13849304 ! cerebellum morphogenesis GO:0021587 9 8 0,000 0,06274337 0,13836026 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 0,06274337 0,13822773 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 0,06274337 0,13809546 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 0,06274337 0,13796343 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 0,06274337 0,13783166 ! sterol catabolic process GO:0016127 9 8 0,000 0,06274337 0,13770014 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 0,06274337 0,13756888 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 0,06274337 0,13743786 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 0,06274337 0,13730709 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 0,06274337 0,13717657 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,06274337 0,1370463 ! S phase GO:0051320 8 8 0,000 0,06274337 0,13691627 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 0,06274337 0,13678649 ! regulation of macrophage differentiation GO:0045649 14 8 0,000 0,06274337 0,13665696 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,06274337 0,13652767 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,06274337 0,13639863 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,06274337 0,13626983 ! hormone catabolic process GO:0042447 13 8 0,000 0,06274337 0,13614127 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,06274337 0,13601296 ! myeloid cell homeostasis GO:0002262 8 8 0,000 0,06274337 0,13588489 ! regulation of fibrinolysis GO:0051917 13 8 0,000 0,06274337 0,13575706 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 0,06274337 0,13562947 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,06274337 0,13550211 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,06274337 0,135375 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,06274337 0,13524813 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 0,06274337 0,13512149 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 0,06274337 0,13499509 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,06274337 0,13486893 ! lamellipodium assembly GO:0030032 9 8 0,000 0,06274337 0,134743 ! regulation of embryonic development GO:0045995 16 8 0,000 0,06274337 0,13461731 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,06274337 0,13449185 GO:0000076|DNA replication checkpoint, ! mitochondrion localization GO:0051646 12 8 0,000 0,06274337 0,13436662 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 0,000 0,06274337 0,13424163 ! muscle fiber development GO:0048747 74 51 1,000 0,06372618 0,13621767 ! establishment of organelle localization GO:0051656 85 52 1,000 0,06593495 0,14080816 ! glycerophospholipid biosynthetic process GO:0046474 75 53 1,000 0,06816907 0,14544422 ! regulation of neurotransmitter levels GO:0001505 73 53 1,000 0,06816907 0,14530942 ! skeletal system morphogenesis GO:0048705 78 53 1,000 0,06816907 0,14517488 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,07030622 0,1495877 ! regulation of developmental growth GO:0048638 13 9 0,000 0,07030622 0,14944944 ! positive regulation of glucose metabolic process GO:0010907 15 9 0,000 0,07030622 0,14931145 ! telencephalon cell migration GO:0022029 16 9 0,000 0,07030622 0,14917371 ! regulation of epithelial cell differentiation GO:0030856 13 9 0,000 0,07030622 0,14903622 ! pentose-phosphate shunt GO:0006098 12 9 0,000 0,07030622 0,14889899 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 0,07030622 0,148762 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 0,07030622 0,14862527 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,07030622 0,1484888 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! positive regulation of GTPase activity GO:0043547 21 9 0,000 0,07030622 0,14835257 ! SMAD protein nuclear translocation GO:0007184 15 9 0,000 0,07030622 0,14821659 ! GTP metabolic process GO:0046039 9 9 0,000 0,07030622 0,14808086 ! elastic fiber assembly GO:0048251 13 9 0,000 0,07030622 0,14794538 ! social behavior GO:0035176 14 9 0,000 0,07030622 0,14781014 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 0,07030622 0,14767516 ! artery development GO:0060840 19 9 0,000 0,07030622 0,14754042 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 0,07030622 0,14740592 ! regulation of glycolysis GO:0006110 15 9 0,000 0,07030622 0,14727167 ! response to pain GO:0048265 16 9 0,000 0,07030622 0,14713767 ! protein complex disassembly GO:0043241 17 9 0,000 0,07030622 0,14700391 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,07030622 0,14687039 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 0,07030622 0,14673711 ! lung alveolus development GO:0048286 17 9 0,000 0,07030622 0,14660408 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,07030622 0,14647128 ! negative regulation of striated muscle development GO:0045843 11 9 0,000 0,07030622 0,14633873 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,07030622 0,14620642 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,07030622 0,14607434 ! ventral spinal cord development GO:0021517 11 9 0,000 0,07030622 0,14594251 ! protein targeting to ER GO:0045047 19 9 0,000 0,07030622 0,14581091 ! T cell selection GO:0045058 18 9 0,000 0,07030622 0,14567955 ! endoderm development GO:0007492 12 9 0,000 0,07030622 0,14554842 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,07030622 0,14541753 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,07030622 0,14528688 ! arginine catabolic process GO:0006527 10 9 0,000 0,07030622 0,14515646 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 0,07030622 0,14502628 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 0,07030622 0,14489632 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 0,07030622 0,14476661 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,07030622 0,14463712 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 12 9 0,000 0,07030622 0,14450786 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 0,07030622 0,14437884 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 0,000 0,07030622 0,14425004 ! regulation of stress fiber formation GO:0051492 20 9 0,000 0,07030622 0,14412148 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,07030622 0,14399314 ! mannose metabolic process GO:0006013 9 9 0,000 0,07030622 0,14386503 ! substrate-bound cell migration GO:0006929 10 9 0,000 0,07030622 0,14373715 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 0,07030622 0,1436095 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,07030622 0,14348208 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 0,07030622 0,14335487 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,07030622 0,1432279 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 0,07030622 0,14310115 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 0,07030622 0,14297462 ! alpha-beta T cell differentiation GO:0046632 14 9 0,000 0,07030622 0,14284832 ! positive regulation of phagocytosis GO:0050766 11 9 0,000 0,07030622 0,14272224 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 0,000 0,07030622 0,14259638 ! blastoderm segmentation GO:0007350 11 9 0,000 0,07030622 0,14247075 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,07030622 0,14234533 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 0,07030622 0,14222014 ! response to amine stimulus GO:0014075 13 9 0,000 0,07030622 0,14209517 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 0,07030622 0,14197041 ! erythrocyte development GO:0048821 11 9 0,000 0,07030622 0,14184588 ! renal water homeostasis GO:0003091 14 9 0,000 0,07030622 0,14172156 ! mRNA cleavage GO:0006379 13 9 0,000 0,07030622 0,14159746 ! hindbrain morphogenesis GO:0021575 12 9 0,000 0,07030622 0,14147358 ! regulation of hormone metabolic process GO:0032350 15 9 0,000 0,07030622 0,14134991 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,07030622 0,14122646 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 0,07030622 0,14110323 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 0,07030622 0,14098021 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 0,07030622 0,1408574 ! acid secretion GO:0046717 14 9 0,000 0,07030622 0,14073481 ! musculoskeletal movement GO:0050881 11 9 0,000 0,07030622 0,14061243 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 0,07030622 0,14049027 ! methionine biosynthetic process GO:0009086 10 9 0,000 0,07030622 0,14036831 ! purine base metabolic process GO:0006144 18 9 0,000 0,07030622 0,14024657 ! thymus development GO:0048538 15 9 0,000 0,07030622 0,14012504 ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 0,07030622 0,14000372 ! spleen development GO:0048536 15 9 0,000 0,07030622 0,13988261 ! anterior/posterior axis specification GO:0009948 11 9 0,000 0,07030622 0,13976171 ! regulation of RNA splicing GO:0043484 14 9 0,000 0,07030622 0,13964102 ! detection of calcium ion GO:0005513 13 9 0,000 0,07030622 0,13952053 ! blastocyst formation GO:0001825 12 9 0,000 0,07030622 0,13940026 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,07030622 0,13928019 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 0,000 0,07030622 0,13916033 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 0,07030622 0,13904067 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,07030622 0,13892122 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,07030622 0,13880197 ! positive regulation of amine transport GO:0051954 15 9 0,000 0,07030622 0,13868293 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 0,07030622 0,13856409 ! prepulse inhibition GO:0060134 14 9 0,000 0,07030622 0,13844546 ! embryonic placenta development GO:0001892 12 9 0,000 0,07030622 0,13832703 ! positive regulation of protein polymerization GO:0032273 15 9 0,000 0,07030622 0,1382088 ! insulin secretion GO:0030073 17 9 0,000 0,07030622 0,13809078 ! sequestering of metal ion GO:0051238 11 9 0,000 0,07030622 0,13797295 ! response to nicotine GO:0035094 16 9 0,000 0,07030622 0,13785533 ! establishment of cell polarity GO:0030010 12 9 0,000 0,07030622 0,1377379 ! nucleus localization GO:0051647 15 9 0,000 0,07030622 0,13762068 ! regulation of synapse organization GO:0050807 12 9 0,000 0,07030622 0,13750366 ! localization within membrane GO:0051668 15 9 0,000 0,07030622 0,13738683 ! regulation of protein complex assembly GO:0043254 81 54 1,000 0,070428 0,13750798 ! DNA catabolic process GO:0006308 67 54 1,000 0,070428 0,13739135 ! detection of external stimulus GO:0009581 66 54 1,000 0,070428 0,13727491 ! negative regulation of response to stimulus GO:0048585 80 56 1,000 0,07501811 0,14609793 ! gonad development GO:0008406 79 57 1,000 0,07734824 0,15050843 ! negative regulation of muscle development GO:0048635 12 10 0,000 0,07780847 0,15127597 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,07780847 0,15114821 ! neuron fate specification GO:0048665 11 10 0,000 0,07780847 0,15102065 ! negative regulation of blood pressure GO:0045776 22 10 0,000 0,07780847 0,15089332 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 0,07780847 0,1507662 ! thyroid gland development GO:0030878 19 10 0,000 0,07780847 0,15063929 ! regulation of B cell proliferation GO:0030888 15 10 0,000 0,07780847 0,15051259 ! regulation of phosphatase activity GO:0010921 21 10 0,000 0,07780847 0,15038611 ! synapsis GO:0007129 13 10 0,000 0,07780847 0,15025984 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 0,07780847 0,15013379 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 0,07780847 0,15000794 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,07780847 0,14988231 GO:0007520|myoblast fusion, ! hair follicle morphogenesis GO:0031069 17 10 0,000 0,07780847 0,14975688 ! sulfate transport GO:0008272 12 10 0,000 0,07780847 0,14963167 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 0,07780847 0,14950666 GO:0048200|Golgi transport vesicle coating, ! regulation of cell projection assembly GO:0060491 20 10 0,000 0,07780847 0,14938187 ! androgen metabolic process GO:0008209 13 10 0,000 0,07780847 0,14925728 ! phospholipid efflux GO:0033700 16 10 0,000 0,07780847 0,1491329 ! hippocampus development GO:0021766 19 10 0,000 0,07780847 0,14900872 ! blood vessel remodeling GO:0001974 21 10 0,000 0,07780847 0,14888475 ! positive regulation of heart contraction GO:0045823 14 10 0,000 0,07780847 0,14876099 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 0,07780847 0,14863744 ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 0,07780847 0,14851409 ! pathogenesis GO:0009405 13 10 0,000 0,07780847 0,14839094 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,07780847 0,148268 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,07780847 0,14814526 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 0,07780847 0,14802273 ! peptide or protein amino-terminal blocking GO:0018409 14 10 0,000 0,07780847 0,14790039 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 0,07780847 0,14777826 ! melanocyte differentiation GO:0030318 15 10 0,000 0,07780847 0,14765633 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 0,07780847 0,1475346 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 0,07780847 0,14741308 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,07780847 0,14729175 ! B cell proliferation GO:0042100 14 10 0,000 0,07780847 0,14717062 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 0,07780847 0,14704969 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,07780847 0,14692896 ! forebrain cell migration GO:0021885 17 10 0,000 0,07780847 0,14680843 ! lipid digestion GO:0044241 15 10 0,000 0,07780847 0,14668809 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,07780847 0,14656796 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,07780847 0,14644802 ! UV protection GO:0009650 14 10 0,000 0,07780847 0,14632827 ! entry into host cell GO:0030260 20 10 0,000 0,07780847 0,14620872 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 16 10 0,000 0,07780847 0,14608937 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,07780847 0,14597021 ! negative regulation of ossification GO:0030279 19 10 0,000 0,07780847 0,14585124 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 0,07780847 0,14573247 ! regulation of bone resorption GO:0045124 24 10 0,000 0,07780847 0,14561389 ! alpha-beta T cell activation GO:0046631 16 10 0,000 0,07780847 0,14549551 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 0,07780847 0,14537732 ! regulation of organ growth GO:0046620 11 10 0,000 0,07780847 0,14525931 ! response to dsRNA GO:0043331 18 10 0,000 0,07780847 0,1451415 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 0,07780847 0,14502389 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,07780847 0,14490646 ! embryonic axis specification GO:0000578 12 10 0,000 0,07780847 0,14478922 ! regulation of B cell differentiation GO:0045577 16 10 0,000 0,07780847 0,14467217 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,07780847 0,14455531 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,07780847 0,14443864 ! cranial nerve development GO:0021545 12 10 0,000 0,07780847 0,14432216 ! fucose catabolic process GO:0019317 16 10 0,000 0,07780847 0,14420586 GO:0042355|L-fucose catabolic process, ! DNA methylation GO:0006306 15 10 0,000 0,07780847 0,14408975 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 0,07780847 0,14397383 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,07780847 0,1438581 ! zymogen activation GO:0031638 14 10 0,000 0,07780847 0,14374255 ! salivary gland development GO:0007431 22 10 0,000 0,07780847 0,14362719 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,07780847 0,14351201 ! glutathione biosynthetic process GO:0006750 11 10 0,000 0,07780847 0,14339702 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,07780847 0,14328221 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 0,07780847 0,14316758 ! positive regulation of leukocyte migration GO:0002687 23 10 0,000 0,07780847 0,14305314 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 0,07780847 0,14293888 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,07780847 0,1428248 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 0,07780847 0,1427109 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 0,000 0,07780847 0,14259719 GO:0043470|regulation of carbohydrate catabolic process, ! positive regulation of JNK cascade GO:0046330 14 10 0,000 0,07780847 0,14248366 ! detection of bacterium GO:0016045 10 10 0,000 0,07780847 0,14237031 ! embryonic gut development GO:0048566 11 10 0,000 0,07780847 0,14225713 ! activation of innate immune response GO:0002218 10 10 0,000 0,07780847 0,14214414 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 21 10 0,000 0,07780847 0,14203133 ! cardiac cell differentiation GO:0035051 16 10 0,000 0,07780847 0,1419187 ! developmental induction GO:0031128 13 10 0,000 0,07780847 0,14180624 GO:0045168|cell-cell signaling involved in cell fate specification, ! T cell receptor signaling pathway GO:0050852 18 10 0,000 0,07780847 0,14169396 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 0,07780847 0,14158186 ! negative regulation of immune effector process GO:0002698 16 10 0,000 0,07780847 0,14146994 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 1,000 0,08207607 0,14911134 ! lung development GO:0030324 94 59 1,000 0,08207607 0,14899365 ! actin filament organization GO:0007015 95 59 1,000 0,08207607 0,14887615 ! myeloid cell differentiation GO:0030099 85 59 1,000 0,08207607 0,14875883 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 1,000 0,08447274 0,15298213 ! embryonic limb morphogenesis GO:0030326 86 60 1,000 0,08447274 0,15286177 GO:0035113|embryonic appendage morphogenesis, ! glycerolipid biosynthetic process GO:0045017 85 60 1,000 0,08447274 0,15274159 ! rRNA transcription GO:0009303 17 11 0,000 0,0852506 0,15402701 ! respiratory burst GO:0045730 14 11 0,000 0,0852506 0,15390611 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 0,0852506 0,1537854 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 0,0852506 0,15366488 ! cortical cytoskeleton organization GO:0030865 20 11 0,000 0,0852506 0,15354455 ! virus-host interaction GO:0019048 17 11 0,000 0,0852506 0,1534244 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 0,000 0,0852506 0,15330445 ! filopodium assembly GO:0046847 19 11 0,000 0,0852506 0,15318468 ! Golgi vesicle budding GO:0048194 17 11 0,000 0,0852506 0,1530651 ! regulation of positive chemotaxis GO:0050926 17 11 0,000 0,0852506 0,1529457 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 14 11 0,000 0,0852506 0,15282649 ! T cell proliferation GO:0042098 20 11 0,000 0,0852506 0,15270747 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 0,0852506 0,15258863 ! positive regulation of endothelial cell proliferation GO:0001938 18 11 0,000 0,0852506 0,15246998 ! bone resorption GO:0045453 16 11 0,000 0,0852506 0,15235151 ! regulated secretory pathway GO:0045055 14 11 0,000 0,0852506 0,15223322 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 0,0852506 0,15211512 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 0,0852506 0,1519972 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 0,0852506 0,15187946 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 0,0852506 0,15176191 ! syncytium formation GO:0006949 15 11 0,000 0,0852506 0,15164454 ! plasma membrane organization GO:0007009 18 11 0,000 0,0852506 0,15152735 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,0852506 0,15141034 ! focal adhesion formation GO:0048041 24 11 0,000 0,0852506 0,15129351 ! mitotic spindle organization GO:0007052 15 11 0,000 0,0852506 0,15117686 ! cellular carbohydrate catabolic process GO:0044275 13 11 0,000 0,0852506 0,15106039 ! membrane protein proteolysis GO:0033619 18 11 0,000 0,0852506 0,1509441 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 0,0852506 0,15082799 ! adult heart development GO:0007512 11 11 0,000 0,0852506 0,15071206 ! chondrocyte differentiation GO:0002062 17 11 0,000 0,0852506 0,1505963 ! temperature homeostasis GO:0001659 16 11 0,000 0,0852506 0,15048073 ! L-glutamate transport GO:0015813 16 11 0,000 0,0852506 0,15036533 GO:0015800|acidic amino acid transport, ! regulation of vascular endothelial growth factor production GO:0010574 19 11 0,000 0,0852506 0,15025011 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,0852506 0,15013506 ! protein targeting to peroxisome GO:0006625 20 11 0,000 0,0852506 0,15002019 ! stem cell development GO:0048864 29 11 0,000 0,0852506 0,1499055 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 0,0852506 0,14979098 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 0,0852506 0,14967663 ! regulation of phagocytosis GO:0050764 14 11 0,000 0,0852506 0,14956246 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 0,0852506 0,14944847 ! vasoconstriction GO:0042310 15 11 0,000 0,0852506 0,14933464 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 0,0852506 0,149221 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,0852506 0,14910752 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 0,0852506 0,14899422 ! regulation of Rho GTPase activity GO:0032319 18 11 0,000 0,0852506 0,14888108 ! ribosome assembly GO:0042255 13 11 0,000 0,0852506 0,14876812 ! nucleosome positioning GO:0016584 13 11 0,000 0,0852506 0,14865534 ! T cell homeostasis GO:0043029 20 11 0,000 0,0852506 0,14854272 ! regulation of isotype switching GO:0045191 19 11 0,000 0,0852506 0,14843027 ! regulation of leukocyte migration GO:0002685 24 11 0,000 0,0852506 0,14831799 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 0,0852506 0,14820589 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,0852506 0,14809395 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 0,0852506 0,14798218 ! aromatic amino acid family catabolic process GO:0009074 13 11 0,000 0,0852506 0,14787058 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 0,0852506 0,14775915 ! male genitalia development GO:0030539 13 11 0,000 0,0852506 0,14764788 ! cholesterol efflux GO:0033344 19 11 0,000 0,0852506 0,14753679 ! digestive tract morphogenesis GO:0048546 15 11 0,000 0,0852506 0,14742586 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 21 11 0,000 0,0852506 0,14731509 ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 0,0852506 0,1472045 ! negative regulation of glucose import GO:0046325 14 11 0,000 0,0852506 0,14709406 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 18 11 0,000 0,0852506 0,1469838 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,0852506 0,1468737 ! defense response to fungus GO:0050832 12 11 0,000 0,0852506 0,14676376 ! lysogeny GO:0030069 18 11 0,000 0,0852506 0,14665399 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 0,0852506 0,14654439 ! acrosome reaction GO:0007340 13 11 0,000 0,0852506 0,14643494 ! lipoprotein metabolic process GO:0042157 89 61 1,000 0,08689059 0,14914057 ! extracellular matrix organization GO:0030198 103 61 1,000 0,08689059 0,14902935 ! neurotransmitter transport GO:0006836 81 62 1,000 0,08932913 0,15309761 ! negative regulation of cell growth GO:0030308 106 62 1,000 0,08932913 0,15298361 ! respiratory tube development GO:0030323 99 62 1,000 0,08932913 0,15286978 ! lymphocyte mediated immunity GO:0002449 88 62 1,000 0,08932913 0,15275613 ! organelle localization GO:0051640 96 62 1,000 0,08932913 0,15264264 ! regulation of transcription factor activity GO:0051090 97 63 1,000 0,09178786 0,1567276 GO:0090046|regulation of transcription regulator activity, ! cAMP-mediated signaling GO:0019933 97 63 1,000 0,09178786 0,15661133 ! lactation GO:0007595 20 12 0,000 0,0926331 0,15793635 ! reproductive cellular process GO:0048610 14 12 0,000 0,0926331 0,15781936 ! tRNA modification GO:0006400 14 12 0,000 0,0926331 0,15770255 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 0,0926331 0,1575859 ! positive regulation of blood pressure GO:0045777 16 12 0,000 0,0926331 0,15746943 ! positive regulation of cellular catabolic process GO:0031331 22 12 0,000 0,0926331 0,15735313 ! 'de novo' protein folding GO:0006458 18 12 0,000 0,0926331 0,157237 ! dicarboxylic acid transport GO:0006835 22 12 0,000 0,0926331 0,15712105 ! phospholipid catabolic process GO:0009395 14 12 0,000 0,0926331 0,15700526 ! peroxisomal transport GO:0043574 21 12 0,000 0,0926331 0,15688965 ! cartilage condensation GO:0001502 18 12 0,000 0,0926331 0,1567742 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 0,0926331 0,15665893 ! cytokine biosynthetic process GO:0042089 16 12 0,000 0,0926331 0,15654382 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,0926331 0,15642888 ! heart looping GO:0001947 15 12 0,000 0,0926331 0,15631412 ! palate development GO:0060021 15 12 0,000 0,0926331 0,15619952 ! positive regulation of cell growth GO:0030307 16 12 0,000 0,0926331 0,15608508 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 0,0926331 0,15597082 ! regulation of skeletal muscle fiber development GO:0048742 20 12 0,000 0,0926331 0,15585672 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,0926331 0,15574279 ! arginine metabolic process GO:0006525 13 12 0,000 0,0926331 0,15562903 ! glycoprotein catabolic process GO:0006516 19 12 0,000 0,0926331 0,15551543 ! methionine metabolic process GO:0006555 13 12 0,000 0,0926331 0,155402 ! tyrosine metabolic process GO:0006570 14 12 0,000 0,0926331 0,15528873 ! Golgi organization GO:0007030 18 12 0,000 0,0926331 0,15517563 ! cell-cell junction assembly GO:0007043 18 12 0,000 0,0926331 0,15506269 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 0,0926331 0,15494992 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,0926331 0,15483731 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 0,000 0,0926331 0,15472487 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! neutral amino acid transport GO:0015804 19 12 0,000 0,0926331 0,15461258 ! L-amino acid transport GO:0015807 20 12 0,000 0,0926331 0,15450046 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 0,0926331 0,15438851 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,0926331 0,15427671 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 0,0926331 0,15416508 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,0926331 0,15405361 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 0,0926331 0,1539423 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 0,0926331 0,15383115 ! cerebellum development GO:0021549 13 12 0,000 0,0926331 0,15372016 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,0926331 0,15360933 ! histone acetylation GO:0016573 23 12 0,000 0,0926331 0,15349866 ! histone methylation GO:0016571 15 12 0,000 0,0926331 0,15338815 ! autonomic nervous system development GO:0048483 23 12 0,000 0,0926331 0,1532778 ! gland morphogenesis GO:0022612 23 12 0,000 0,0926331 0,15316761 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 0,0926331 0,15305757 ! peptidyl-lysine modification GO:0018205 18 12 0,000 0,0926331 0,1529477 ! negative regulation of protein secretion GO:0050709 20 12 0,000 0,0926331 0,15283798 ! regulation of epidermis development GO:0045682 17 12 0,000 0,0926331 0,15272842 ! intestinal absorption GO:0050892 19 12 0,000 0,0926331 0,15261901 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 0,0926331 0,15250976 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,0926331 0,15240067 ! regulation of mRNA stability GO:0043488 27 12 0,000 0,0926331 0,15229174 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 0,000 0,0926331 0,15218296 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,0926331 0,15207433 ! microspike assembly GO:0030035 23 12 0,000 0,0926331 0,15196586 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 0,0926331 0,15185755 ! response to cold GO:0009409 14 12 0,000 0,0926331 0,15174939 ! negative regulation of cell size GO:0045792 108 64 1,000 0,09426631 0,15431496 ! appendage morphogenesis GO:0035107 93 64 1,000 0,09426631 0,15420521 GO:0035108|limb morphogenesis, ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 1,000 0,09426631 0,15409561 ! respiratory system development GO:0060541 100 64 1,000 0,09426631 0,15398616 ! adaptive immune response GO:0002250 94 64 1,000 0,09426631 0,15387688 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! appendage development GO:0048736 94 65 1,000 0,09676401 0,15784201 GO:0060173|limb development, ! axon guidance GO:0007411 99 66 1,000 0,0992805 0,16183214 ! N-terminal protein amino acid modification GO:0031365 18 13 0,000 0,09995644 0,16281857 ! positive regulation of protein complex assembly GO:0031334 19 13 0,000 0,09995644 0,16270334 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,09995644 0,16258827 ! cGMP metabolic process GO:0046068 16 13 0,000 0,09995644 0,16247337 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 17 13 0,000 0,09995644 0,16235863 ! water transport GO:0006833 17 13 0,000 0,09995644 0,16224405 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,09995644 0,16212963 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,09995644 0,16201538 ! lipid localization GO:0010876 24 13 0,000 0,09995644 0,16190128 GO:0019915|lipid storage, ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,09995644 0,16178735 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 0,09995644 0,16167357 ! organelle fusion GO:0048284 28 13 0,000 0,09995644 0,16155996 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,09995644 0,1614465 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! endocrine pancreas development GO:0031018 19 13 0,000 0,09995644 0,16133321 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 0,000 0,09995644 0,16122007 ! cell differentiation in spinal cord GO:0021515 16 13 0,000 0,09995644 0,16110709 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,09995644 0,16099427 ! response to hexose stimulus GO:0009746 19 13 0,000 0,09995644 0,16088161 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! induction of apoptosis via death domain receptors GO:0008625 15 13 0,000 0,09995644 0,1607691 ! glutamate metabolic process GO:0006536 18 13 0,000 0,09995644 0,16065676 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,09995644 0,16054457 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,09995644 0,16043253 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 0,09995644 0,16032065 ! NAD metabolic process GO:0019674 21 13 0,000 0,09995644 0,16020893 ! exocrine system development GO:0035272 27 13 0,000 0,09995644 0,16009737 ! negative regulation of mitotic cell cycle GO:0045930 23 13 0,000 0,09995644 0,15998596 ! bone mineralization GO:0030282 15 13 0,000 0,09995644 0,1598747 ! regulation of exocytosis GO:0017157 17 13 0,000 0,09995644 0,1597636 ! intermediate filament cytoskeleton organization GO:0045104 23 13 0,000 0,09995644 0,15965265 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 0,09995644 0,15954186 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,09995644 0,15943122 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 0,09995644 0,15932073 ! negative regulation of protein import into nucleus GO:0042308 25 13 0,000 0,09995644 0,1592104 ! genitalia development GO:0048806 15 13 0,000 0,09995644 0,15910022 ! regulation of monooxygenase activity GO:0032768 26 13 0,000 0,09995644 0,15899019 ! tissue regeneration GO:0042246 21 13 0,000 0,09995644 0,15888032 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 0,09995644 0,15877059 ! cofactor transport GO:0051181 19 13 0,000 0,09995644 0,15866102 ! NADP metabolic process GO:0006739 18 13 0,000 0,09995644 0,1585516 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,09995644 0,15844233 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 0,09995644 0,15833321 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,09995644 0,15822424 ! regulation of RNA stability GO:0043487 28 13 0,000 0,09995644 0,15811542 ! heme biosynthetic process GO:0006783 20 13 0,000 0,09995644 0,15800675 ! regulation of axon extension GO:0030516 23 13 0,000 0,09995644 0,15789823 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 0,000 0,09995644 0,15778986 ! lymphocyte homeostasis GO:0002260 24 13 0,000 0,09995644 0,15768163 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,09995644 0,15757356 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,09995644 0,15746563 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,09995644 0,15735785 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,09995644 0,15725022 ! development of primary sexual characteristics GO:0045137 92 68 1,000 0,10436798 0,16407816 ! intracellular protein transmembrane transport GO:0065002 102 68 1,000 0,10436798 0,16396608 ! rhythmic process GO:0048511 105 68 1,000 0,10436798 0,16385416 ! response to drug GO:0042493 108 69 1,000 0,10693807 0,1677746 ! regulation of skeletal muscle tissue development GO:0048641 22 14 0,000 0,10722109 0,16810396 ! G1 phase of mitotic cell cycle GO:0000080 23 14 0,000 0,10722109 0,16798945 ! superoxide anion generation GO:0042554 18 14 0,000 0,10722109 0,16787509 ! neuron maturation GO:0042551 21 14 0,000 0,10722109 0,16776089 ! myotube differentiation GO:0014902 21 14 0,000 0,10722109 0,16764685 ! phosphoinositide phosphorylation GO:0046854 21 14 0,000 0,10722109 0,16753296 ! negative regulation of bone remodeling GO:0046851 26 14 0,000 0,10722109 0,16741922 ! heterophilic cell adhesion GO:0007157 29 14 0,000 0,10722109 0,16730564 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,10722109 0,16719221 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,10722109 0,16707894 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,10722109 0,16696582 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,10722109 0,16685285 ! gene silencing by RNA GO:0031047 20 14 0,000 0,10722109 0,16674003 ! response to cAMP GO:0051591 19 14 0,000 0,10722109 0,16662737 ! limbic system development GO:0021761 25 14 0,000 0,10722109 0,16651486 ! startle response GO:0001964 21 14 0,000 0,10722109 0,1664025 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 0,000 0,10722109 0,1662903 ! activation of MAPKK activity GO:0000186 21 14 0,000 0,10722109 0,16617824 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,10722109 0,16606634 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 0,10722109 0,16595458 ! glycine metabolic process GO:0006544 22 14 0,000 0,10722109 0,16584298 ! pituitary gland development GO:0021983 23 14 0,000 0,10722109 0,16573153 ! negative regulation of microtubule depolymerization GO:0007026 31 14 0,000 0,10722109 0,16562022 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 20 14 0,000 0,10722109 0,16550907 ! regulation of heart rate GO:0002027 23 14 0,000 0,10722109 0,16539806 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,10722109 0,16528721 ! negative regulation of caspase activity GO:0043154 20 14 0,000 0,10722109 0,1651765 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 0,000 0,10722109 0,16506594 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 27 14 0,000 0,10722109 0,16495553 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 0,10722109 0,16484526 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 24 14 0,000 0,10722109 0,16473514 ! axon cargo transport GO:0008088 27 14 0,000 0,10722109 0,16462517 ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,10722109 0,16451535 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 0,10722109 0,16440567 ! T cell differentiation in the thymus GO:0033077 27 14 0,000 0,10722109 0,16429614 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,10722109 0,16418676 ! mRNA splice site selection GO:0006376 26 14 0,000 0,10722109 0,16407752 ! regulation of T-helper 2 type immune response GO:0002828 21 14 0,000 0,10722109 0,16396842 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,10722109 0,16385948 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 0,10722109 0,16375067 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,10722109 0,16364201 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 0,10722109 0,16353349 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 0,10722109 0,16342512 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 0,10722109 0,16331689 ! regulation of ATPase activity GO:0043462 18 14 0,000 0,10722109 0,16320881 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,10722109 0,16310087 ! cell killing GO:0001906 20 14 0,000 0,10722109 0,16299307 ! epithelial to mesenchymal transition GO:0001837 22 14 0,000 0,10722109 0,16288541 ! cilium assembly GO:0042384 20 14 0,000 0,10722109 0,16277789 ! peptide hormone secretion GO:0030072 23 14 0,000 0,10722109 0,16267052 ! response to metal ion GO:0010038 103 70 1,000 0,10952514 0,16605657 ! eye development GO:0001654 111 70 1,000 0,10952514 0,16594718 ! amine transport GO:0015837 101 70 1,000 0,10952514 0,16583793 ! positive regulation of phosphorylation GO:0042327 102 70 1,000 0,10952514 0,16572883 ! leukocyte mediated immunity GO:0002443 99 71 1,000 0,11212875 0,16955696 ! steroid biosynthetic process GO:0006694 94 71 1,000 0,11212875 0,16944555 ! lymphocyte differentiation GO:0030098 113 71 1,000 0,11212875 0,16933429 ! regulation of protein ubiquitination GO:0031396 19 15 0,000 0,11442752 0,17269245 ! positive regulation of cell size GO:0045793 20 15 0,000 0,11442752 0,1725792 ! metencephalon development GO:0022037 19 15 0,000 0,11442752 0,17246611 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,11442752 0,17235317 ! negative regulation of hormone secretion GO:0046888 20 15 0,000 0,11442752 0,17224037 ! negative regulation of cell cycle process GO:0010948 24 15 0,000 0,11442752 0,17212772 ! skin development GO:0043588 25 15 0,000 0,11442752 0,17201522 ! embryonic forelimb morphogenesis GO:0035115 17 15 0,000 0,11442752 0,17190287 ! lipid phosphorylation GO:0046834 23 15 0,000 0,11442752 0,17179066 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,11442752 0,1716786 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 0,11442752 0,17156668 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 0,11442752 0,17145491 ! adult walking behavior GO:0007628 25 15 0,000 0,11442752 0,17134329 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,11442752 0,17123181 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,11442752 0,17112047 ! myoblast differentiation GO:0045445 27 15 0,000 0,11442752 0,17100928 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,11442752 0,17089824 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 0,11442752 0,17078734 ! cerebral cortex development GO:0021987 29 15 0,000 0,11442752 0,17067658 ! response to osmotic stress GO:0006970 22 15 0,000 0,11442752 0,17056597 ! vesicle coating GO:0006901 25 15 0,000 0,11442752 0,1704555 ! regulation of the force of heart contraction GO:0002026 21 15 0,000 0,11442752 0,17034517 ! DNA integration GO:0015074 22 15 0,000 0,11442752 0,17023499 ! peptide secretion GO:0002790 27 15 0,000 0,11442752 0,17012494 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,11442752 0,17001504 ! regulation of vasodilation GO:0042312 24 15 0,000 0,11442752 0,16990529 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 0,11442752 0,16979567 ! neuron recognition GO:0008038 22 15 0,000 0,11442752 0,16968619 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,11442752 0,16957686 ! positive regulation of oxidoreductase activity GO:0051353 21 15 0,000 0,11442752 0,16946767 ! negative regulation of tissue remodeling GO:0034104 27 15 0,000 0,11442752 0,16935861 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,11442752 0,1692497 ! biomineral formation GO:0031214 18 15 0,000 0,11442752 0,16914093 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,11442752 0,1690323 ! regulation of T-helper cell differentiation GO:0045622 23 15 0,000 0,11442752 0,1689238 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,11442752 0,16881545 ! organic cation transport GO:0015695 19 15 0,000 0,11442752 0,16870724 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,11442752 0,16859916 GO:0033014|tetrapyrrole biosynthetic process, ! defense response to virus GO:0051607 27 15 0,000 0,11442752 0,16849122 ! peptide hormone processing GO:0016486 19 15 0,000 0,11442752 0,16838342 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 0,000 0,11442752 0,16827576 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 1,000 0,11474848 0,16863993 GO:0045937|positive regulation of phosphate metabolic process, ! negative regulation of organelle organization GO:0010639 115 72 1,000 0,11474848 0,16853224 ! regulation of synaptic transmission GO:0050804 109 72 1,000 0,11474848 0,16842469 ! tube morphogenesis GO:0035239 118 73 1,000 0,11738389 0,172183 ! response to steroid hormone stimulus GO:0048545 114 73 1,000 0,11738389 0,17207326 ! phospholipid biosynthetic process GO:0008654 102 74 1,000 0,12003457 0,17584682 ! protein import into nucleus GO:0006606 118 74 1,000 0,12003457 0,17573489 ! protein secretion GO:0009306 27 16 0,000 0,12157618 0,17787864 ! hormone secretion GO:0046879 25 16 0,000 0,12157618 0,17776555 ! bone remodeling GO:0046849 24 16 0,000 0,12157618 0,17765261 ! protein amino acid acetylation GO:0006473 28 16 0,000 0,12157618 0,17753982 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,12157618 0,17742717 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,12157618 0,17731466 ! glial cell development GO:0021782 24 16 0,000 0,12157618 0,17720229 ! patterning of blood vessels GO:0001569 24 16 0,000 0,12157618 0,17709007 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,12157618 0,17697798 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,12157618 0,17686604 ! protein polyubiquitination GO:0000209 26 16 0,000 0,12157618 0,17675424 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,12157618 0,17664259 ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 0,12157618 0,17653107 ! regulation of protein binding GO:0043393 27 16 0,000 0,12157618 0,17641969 ! regulation of dephosphorylation GO:0035303 33 16 0,000 0,12157618 0,17630846 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 0,000 0,12157618 0,17619736 ! protein export from nucleus GO:0006611 24 16 0,000 0,12157618 0,17608641 ! negative regulation of immune response GO:0050777 28 16 0,000 0,12157618 0,17597559 ! DNA replication initiation GO:0006270 25 16 0,000 0,12157618 0,17586492 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 0,000 0,12157618 0,17575438 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,12157618 0,17564398 ! diencephalon development GO:0021536 25 16 0,000 0,12157618 0,17553372 ! neural crest cell migration GO:0001755 24 16 0,000 0,12157618 0,1754236 ! G1 phase GO:0051318 27 16 0,000 0,12157618 0,17531361 ! neutrophil chemotaxis GO:0030593 21 16 0,000 0,12157618 0,17520377 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,12157618 0,17509406 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 0,12157618 0,17498449 ! steroid catabolic process GO:0006706 22 16 0,000 0,12157618 0,17487506 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,12157618 0,17476576 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 0,000 0,12157618 0,1746566 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,12157618 0,17454757 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,12157618 0,17443869 ! sperm-egg recognition GO:0035036 16 16 0,000 0,12157618 0,17432993 GO:0007339|binding of sperm to zona pellucida, ! nerve development GO:0021675 18 16 0,000 0,12157618 0,17422132 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 0,000 0,12157618 0,17411284 ! inner ear receptor cell differentiation GO:0060113 30 16 0,000 0,12157618 0,17400449 ! negative regulation of translation GO:0017148 22 16 0,000 0,12157618 0,17389628 ! blood coagulation GO:0007596 116 75 1,000 0,1227001 0,1753948 GO:0050817|coagulation, ! response to inorganic substance GO:0010035 115 75 1,000 0,1227001 0,17528586 ! negative regulation of growth GO:0045926 123 75 1,000 0,1227001 0,17517706 ! nuclear import GO:0051170 121 75 1,000 0,1227001 0,17506839 ! tRNA metabolic process GO:0006399 95 76 1,000 0,12538009 0,17878128 ! response to unfolded protein GO:0006986 99 76 1,000 0,12538009 0,17867051 ! regulation of cell morphogenesis GO:0022604 140 76 1,000 0,12538009 0,17855988 ! regulation of adenylate cyclase activity GO:0045761 131 77 1,000 0,12807412 0,18228371 ! regulation of DNA binding GO:0051101 119 77 1,000 0,12807412 0,18217098 ! protein ubiquitination GO:0016567 125 77 1,000 0,12807412 0,18205839 ! regulation of transmission of nerve impulse GO:0051969 116 77 1,000 0,12807412 0,18194593 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,12866754 0,18267614 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,12866754 0,18256345 ! negative regulation of defense response GO:0031348 19 17 0,000 0,12866754 0,18245089 ! positive regulation of hormone secretion GO:0046887 24 17 0,000 0,12866754 0,18233848 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 0,12866754 0,1822262 ! glycerol metabolic process GO:0006071 20 17 0,000 0,12866754 0,18211406 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,12866754 0,18200206 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,12866754 0,1818902 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,12866754 0,18177847 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,12866754 0,18166688 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 0,000 0,12866754 0,18155543 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,12866754 0,18144411 ! forelimb morphogenesis GO:0035136 19 17 0,000 0,12866754 0,18133294 ! memory GO:0007613 25 17 0,000 0,12866754 0,18122189 ! keratinization GO:0031424 17 17 0,000 0,12866754 0,18111099 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,12866754 0,18100021 ! negative regulation of peptidase activity GO:0010466 23 17 0,000 0,12866754 0,18088958 ! retinoid metabolic process GO:0001523 22 17 0,000 0,12866754 0,18077908 GO:0016101|diterpenoid metabolic process, ! inactivation of MAPK activity GO:0000188 27 17 0,000 0,12866754 0,18066871 ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,12866754 0,18055848 ! vacuolar transport GO:0007034 24 17 0,000 0,12866754 0,18044839 ! cell-substrate junction assembly GO:0007044 39 17 0,000 0,12866754 0,18033842 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 0,000 0,12866754 0,18022859 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,12866754 0,1801189 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,12866754 0,18000934 ! membrane budding GO:0006900 29 17 0,000 0,12866754 0,17989991 ! heme metabolic process GO:0042168 27 17 0,000 0,12866754 0,17979061 ! actin filament bundle formation GO:0051017 26 17 0,000 0,12866754 0,17968145 ! body fluid secretion GO:0007589 27 17 0,000 0,12866754 0,17957242 ! stem cell differentiation GO:0048863 36 17 0,000 0,12866754 0,17946352 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,12866754 0,17935476 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,12866754 0,17924612 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,12866754 0,17913762 ! sensory perception of pain GO:0019233 23 17 0,000 0,12866754 0,17902925 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,12866754 0,17892101 GO:0002712|regulation of B cell mediated immunity, ! synaptogenesis GO:0007416 24 17 0,000 0,12866754 0,1788129 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,12866754 0,17870492 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,12866754 0,17859707 ! cell-cell junction organization GO:0045216 25 17 0,000 0,12866754 0,17848936 ! regulation of immunoglobulin production GO:0002637 25 17 0,000 0,12866754 0,17838177 ! proximal/distal pattern formation GO:0009954 25 17 0,000 0,12866754 0,17827431 ! aromatic compound catabolic process GO:0019439 22 17 0,000 0,12866754 0,17816698 ! negative regulation of homeostatic process GO:0032845 28 17 0,000 0,12866754 0,17805978 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,12866754 0,17795271 ! negative regulation of coagulation GO:0050819 23 17 0,000 0,12866754 0,17784576 ! positive regulation of protein modification process GO:0031401 107 78 1,000 0,1307818 0,18065954 ! regulation of cyclase activity GO:0031279 132 78 1,000 0,1307818 0,1805511 ! regulation of cAMP biosynthetic process GO:0030817 136 79 1,000 0,13350273 0,18419693 ! T cell activation GO:0042110 134 79 1,000 0,13350273 0,1840865 ! regulation of lyase activity GO:0051339 133 79 1,000 0,13350273 0,18397621 ! positive regulation of DNA replication GO:0045740 29 18 0,000 0,13570206 0,18689506 ! positive regulation of translation GO:0045727 28 18 0,000 0,13570206 0,18678321 ! positive regulation of angiogenesis GO:0045766 35 18 0,000 0,13570206 0,1866715 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,13570206 0,18655992 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 0,13570206 0,18644847 ! cAMP metabolic process GO:0046058 33 18 0,000 0,13570206 0,18633716 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,13570206 0,18622598 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 0,13570206 0,18611493 ! axis specification GO:0009798 26 18 0,000 0,13570206 0,18600402 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,13570206 0,18589324 GO:0050886|endocrine process, ! mechanoreceptor differentiation GO:0042490 32 18 0,000 0,13570206 0,18578259 ! pancreas development GO:0031016 26 18 0,000 0,13570206 0,18567207 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,13570206 0,18556168 ! glutamine metabolic process GO:0006541 23 18 0,000 0,13570206 0,18545142 ! response to retinoic acid GO:0032526 25 18 0,000 0,13570206 0,1853413 ! pigmentation during development GO:0048066 31 18 0,000 0,13570206 0,1852313 ! positive regulation of cytoskeleton organization GO:0051495 33 18 0,000 0,13570206 0,18512144 ! fucose metabolic process GO:0006004 26 18 0,000 0,13570206 0,1850117 ! response to fungus GO:0009620 19 18 0,000 0,13570206 0,1849021 ! peptide cross-linking GO:0018149 31 18 0,000 0,13570206 0,18479263 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 0,000 0,13570206 0,18468328 ! heart process GO:0003015 27 18 0,000 0,13570206 0,18457407 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,13570206 0,18446498 GO:0006692|prostanoid metabolic process, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,13570206 0,18435602 ! visual learning GO:0008542 35 18 0,000 0,13570206 0,18424719 ! somitogenesis GO:0001756 24 18 0,000 0,13570206 0,18413849 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,13570206 0,18402992 ! detection of chemical stimulus GO:0009593 26 18 0,000 0,13570206 0,18392148 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,13570206 0,18381316 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,13570206 0,18370497 ! vitamin transport GO:0051180 24 18 0,000 0,13570206 0,18359691 ! hormone transport GO:0009914 27 18 0,000 0,13570206 0,18348897 ! negative regulation of neuron differentiation GO:0045665 24 18 0,000 0,13570206 0,18338117 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,13570206 0,18327349 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,13570206 0,18316593 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,13570206 0,1830585 ! cell-cell recognition GO:0009988 20 18 0,000 0,13570206 0,1829512 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,13570206 0,18284402 ! estrogen receptor signaling pathway GO:0030520 30 18 0,000 0,13570206 0,18273697 ! regulation of glucose import GO:0046324 21 18 0,000 0,13570206 0,18263004 GO:0010827|regulation of glucose transport, ! gut development GO:0048565 26 18 0,000 0,13570206 0,18252324 ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 0,000 0,13570206 0,18241657 ! protein localization in nucleus GO:0034504 133 80 1,000 0,13623654 0,18302807 ! regulation of cAMP metabolic process GO:0030814 141 81 1,000 0,13898285 0,18660861 ! hemostasis GO:0007599 125 81 1,000 0,13898285 0,18649974 ! mRNA transport GO:0051028 121 81 1,000 0,13898285 0,18639099 ! regulation of cell cycle process GO:0010564 122 81 1,000 0,13898285 0,18628237 ! response to protein stimulus GO:0051789 111 81 1,000 0,13898285 0,18617388 ! regulation of neurological system process GO:0031644 122 81 1,000 0,13898285 0,18606551 ! detection of stimulus GO:0051606 108 82 1,000 0,14174127 0,189648 ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,14268019 0,19079328 ! positive regulation of fibroblast proliferation GO:0048146 27 19 0,000 0,14268019 0,19068242 ! positive regulation of ossification GO:0045778 30 19 0,000 0,14268019 0,19057168 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,14268019 0,19046108 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 0,000 0,14268019 0,1903506 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 0,000 0,14268019 0,19024025 ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,14268019 0,19013003 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,14268019 0,19001994 ! regeneration GO:0031099 32 19 0,000 0,14268019 0,18990998 ! calcium-independent cell-cell adhesion GO:0016338 21 19 0,000 0,14268019 0,18980014 ! sensory perception of taste GO:0050909 23 19 0,000 0,14268019 0,18969043 ! smooth muscle contraction GO:0006939 36 19 0,000 0,14268019 0,18958084 ! peroxisome organization GO:0007031 29 19 0,000 0,14268019 0,18947138 ! digestive system process GO:0022600 30 19 0,000 0,14268019 0,18936205 ! cellular response to reactive oxygen species GO:0034614 27 19 0,000 0,14268019 0,18925285 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,14268019 0,18914377 ! response to vitamin A GO:0033189 26 19 0,000 0,14268019 0,18903481 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,14268019 0,18892599 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,14268019 0,18881728 ! sex determination GO:0007530 29 19 0,000 0,14268019 0,1887087 ! response to lipopolysaccharide GO:0032496 26 19 0,000 0,14268019 0,18860025 ! plasma membrane fusion GO:0045026 23 19 0,000 0,14268019 0,18849192 ! regulation of endothelial cell migration GO:0010594 40 19 0,000 0,14268019 0,18838372 ! cytolysis GO:0019835 20 19 0,000 0,14268019 0,18827564 ! renal system process GO:0003014 35 19 0,000 0,14268019 0,18816768 ! vasodilation GO:0042311 33 19 0,000 0,14268019 0,18805985 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,14268019 0,18795214 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,14268019 0,18784455 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,14268019 0,18773709 ! negative regulation of angiogenesis GO:0016525 36 19 0,000 0,14268019 0,18762975 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,14268019 0,18752254 ! sarcomere organization GO:0045214 23 19 0,000 0,14268019 0,18741544 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,14268019 0,18730847 ! aromatic amino acid family metabolic process GO:0009072 24 19 0,000 0,14268019 0,18720162 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,14268019 0,18709489 GO:0043450|alkene biosynthetic process, ! embryonic organ morphogenesis GO:0048562 23 19 0,000 0,14268019 0,18698828 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 0,14268019 0,1868818 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 0,000 0,14268019 0,18677543 ! regulation of nucleotide biosynthetic process GO:0030808 141 83 1,000 0,14451143 0,18906501 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! biogenic amine metabolic process GO:0006576 121 83 1,000 0,14451143 0,18895753 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,14960237 0,1955031 ! iron ion transport GO:0006826 37 20 0,000 0,14960237 0,19539208 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,14960237 0,19528119 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,14960237 0,19517043 GO:0006044|N-acetylglucosamine metabolic process, ! microtubule-based transport GO:0010970 37 20 0,000 0,14960237 0,19505978 ! response to vitamin GO:0033273 29 20 0,000 0,14960237 0,19494927 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,14960237 0,19483888 ! spinal cord development GO:0021510 31 20 0,000 0,14960237 0,19472861 ! response to ethanol GO:0045471 37 20 0,000 0,14960237 0,19461847 ! multicellular organismal response to stress GO:0033555 32 20 0,000 0,14960237 0,19450846 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 0,000 0,14960237 0,19439856 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,14960237 0,1942888 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,14960237 0,19417915 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 0,000 0,14960237 0,19406963 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,14960237 0,19396024 ! regulation of ARF GTPase activity GO:0032312 31 20 0,000 0,14960237 0,19385096 ! pallium development GO:0021543 38 20 0,000 0,14960237 0,19374181 ! DNA modification GO:0006304 28 20 0,000 0,14960237 0,19363279 ! positive regulation of locomotion GO:0040017 35 20 0,000 0,14960237 0,19352388 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 45 20 0,000 0,14960237 0,1934151 ! positive regulation of inflammatory response GO:0050729 30 20 0,000 0,14960237 0,19330644 ! positive regulation of osteoblast differentiation GO:0045669 33 20 0,000 0,14960237 0,1931979 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,14960237 0,19308948 ! positive regulation of B cell activation GO:0050871 31 20 0,000 0,14960237 0,19298119 ! collagen catabolic process GO:0030574 25 20 0,000 0,14960237 0,19287302 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,14960237 0,19276496 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 0,14960237 0,19265703 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,14960237 0,19254922 ! alditol metabolic process GO:0019400 24 20 0,000 0,14960237 0,19244153 ! actin filament-based movement GO:0030048 34 20 0,000 0,14960237 0,19233396 ! positive regulation of MAP kinase activity GO:0043406 121 85 1,000 0,15008555 0,19284736 ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 1,000 0,15288879 0,19633959 ! interphase of mitotic cell cycle GO:0051329 156 86 1,000 0,15288879 0,19623003 ! skeletal muscle tissue development GO:0007519 123 87 1,000 0,15570234 0,19972972 GO:0060538|skeletal muscle organ development, ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 0,000 0,15646906 0,20060136 ! regulation of cell killing GO:0031341 34 21 0,000 0,15646906 0,2004896 ! G2/M transition of mitotic cell cycle GO:0000086 33 21 0,000 0,15646906 0,20037797 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,15646906 0,20026646 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,15646906 0,20015508 GO:0009799|determination of symmetry, ! gluconeogenesis GO:0006094 25 21 0,000 0,15646906 0,20004382 ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,15646906 0,19993269 GO:0034105|positive regulation of tissue remodeling, ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,15646906 0,19982168 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,15646906 0,19971079 ! protein amino acid acylation GO:0043543 37 21 0,000 0,15646906 0,19960002 ! regulation of chemotaxis GO:0050920 36 21 0,000 0,15646906 0,19948938 ! vesicle docking GO:0048278 27 21 0,000 0,15646906 0,19937886 ! phototransduction GO:0007602 25 21 0,000 0,15646906 0,19926846 ! dendrite development GO:0016358 35 21 0,000 0,15646906 0,19915818 ! visual behavior GO:0007632 39 21 0,000 0,15646906 0,19904803 ! ovarian follicle development GO:0001541 30 21 0,000 0,15646906 0,198938 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,15646906 0,19882809 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,15646906 0,1987183 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,15646906 0,19860863 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 0,000 0,15646906 0,19849908 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 0,000 0,15646906 0,19838966 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 0,15646906 0,19828035 GO:0060415|muscle tissue morphogenesis, ! leukotriene metabolic process GO:0006691 28 21 0,000 0,15646906 0,19817117 ! regulation of vasoconstriction GO:0019229 31 21 0,000 0,15646906 0,1980621 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,15646906 0,19795316 ! platelet activation GO:0030168 28 21 0,000 0,15646906 0,19784433 ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 0,000 0,15646906 0,19773562 ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,15646906 0,19762704 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,15646906 0,19751857 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,15646906 0,19741022 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,15646906 0,19730199 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,15646906 0,19719388 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,15646906 0,19708589 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,15646906 0,19697802 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,15646906 0,19687026 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,15646906 0,19676262 ! acetyl-CoA catabolic process GO:0046356 31 21 0,000 0,15646906 0,1966551 GO:0006099|tricarboxylic acid cycle, ! regulation of multi-organism process GO:0043900 32 21 0,000 0,15646906 0,1965477 ! interphase GO:0051325 159 88 1,000 0,15852587 0,19902265 ! establishment of RNA localization GO:0051236 128 88 1,000 0,15852587 0,19891407 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! protein processing GO:0016485 114 88 1,000 0,15852587 0,19880561 ! regulation of neurogenesis GO:0050767 153 89 1,000 0,16135903 0,20224837 ! regulation of nucleotide metabolic process GO:0006140 150 89 1,000 0,16135903 0,20213821 ! regulation of T cell activation GO:0050863 128 89 1,000 0,16135903 0,20202818 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 0,000 0,16328069 0,20432295 ! viral genome replication GO:0019079 29 22 0,000 0,16328069 0,20421185 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,16328069 0,20410086 ! spliceosomal snRNP biogenesis GO:0000387 28 22 0,000 0,16328069 0,20399 ! leukocyte adhesion GO:0007159 38 22 0,000 0,16328069 0,20387925 ! molting cycle process GO:0022404 40 22 0,000 0,16328069 0,20376863 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! dicarboxylic acid metabolic process GO:0043648 33 22 0,000 0,16328069 0,20365813 ! glutamate signaling pathway GO:0007215 34 22 0,000 0,16328069 0,20354774 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,16328069 0,20343748 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 0,000 0,16328069 0,20332733 ! vasculogenesis GO:0001570 33 22 0,000 0,16328069 0,20321731 ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 0,000 0,16328069 0,2031074 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of smooth muscle contraction GO:0006940 36 22 0,000 0,16328069 0,20299761 ! lysosome organization GO:0007040 37 22 0,000 0,16328069 0,20288794 ! ureteric bud development GO:0001657 32 22 0,000 0,16328069 0,20277839 ! coenzyme catabolic process GO:0009109 33 22 0,000 0,16328069 0,20266896 ! regulation of behavior GO:0050795 38 22 0,000 0,16328069 0,20255965 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,16328069 0,20245045 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,16328069 0,20234137 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,16328069 0,20223241 ! leukocyte homeostasis GO:0001776 33 22 0,000 0,16328069 0,20212357 ! regulation of blood coagulation GO:0030193 34 22 0,000 0,16328069 0,20201484 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,16328069 0,20190623 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,16328069 0,20179773 ! neural tube closure GO:0001843 33 22 0,000 0,16328069 0,20168936 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,16328069 0,2015811 ! RNA localization GO:0006403 135 91 1,000 0,1670529 0,2061275 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 1,000 0,16991295 0,20954413 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 0,000 0,1700377 0,20958559 ! neuron fate commitment GO:0048663 32 23 0,000 0,1700377 0,20947333 ! embryonic pattern specification GO:0009880 31 23 0,000 0,1700377 0,20936119 ! acetyl-CoA metabolic process GO:0006084 33 23 0,000 0,1700377 0,20924918 ! vesicle targeting GO:0006903 32 23 0,000 0,1700377 0,20913728 ! response to corticosteroid stimulus GO:0031960 36 23 0,000 0,1700377 0,2090255 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 0,000 0,1700377 0,20891384 ! osteoblast differentiation GO:0001649 40 23 0,000 0,1700377 0,2088023 ! interaction with host GO:0051701 37 23 0,000 0,1700377 0,20869088 ! lymphocyte proliferation GO:0046651 36 23 0,000 0,1700377 0,20857958 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,1700377 0,2084684 ! cellular response to oxidative stress GO:0034599 33 23 0,000 0,1700377 0,20835733 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,1700377 0,20824639 ! negative regulation of phosphorylation GO:0042326 41 23 0,000 0,1700377 0,20813556 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,1700377 0,20802485 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,1700377 0,20791425 ! pentose metabolic process GO:0019321 31 23 0,000 0,1700377 0,20780378 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,1700377 0,20769342 ! spermatid development GO:0007286 33 23 0,000 0,1700377 0,20758318 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,1700377 0,20747306 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,1700377 0,20736305 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,1700377 0,20725316 ! telomere organization GO:0032200 32 23 0,000 0,1700377 0,20714339 GO:0000723|telomere maintenance, ! response to molecule of bacterial origin GO:0002237 30 23 0,000 0,1700377 0,20703373 ! regulation of amine transport GO:0051952 38 23 0,000 0,1700377 0,20692419 ! liver development GO:0001889 40 23 0,000 0,1700377 0,20681476 ! peptidyl-amino acid modification GO:0018193 147 93 1,000 0,17278133 0,21004073 ! positive regulation of cell projection organization GO:0031346 39 24 0,000 0,17674053 0,21474021 ! regulation of cellular catabolic process GO:0031329 36 24 0,000 0,17674053 0,21462683 ! initiation of viral infection GO:0019059 42 24 0,000 0,17674053 0,21451357 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,17674053 0,21440043 ! pyruvate metabolic process GO:0006090 29 24 0,000 0,17674053 0,21428741 ! superoxide metabolic process GO:0006801 32 24 0,000 0,17674053 0,21417451 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,17674053 0,21406173 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! insulin receptor signaling pathway GO:0008286 40 24 0,000 0,17674053 0,21394906 ! regulation of endothelial cell proliferation GO:0001936 46 24 0,000 0,17674053 0,21383652 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,17674053 0,21372409 ! sperm motility GO:0030317 27 24 0,000 0,17674053 0,21361178 ! vacuole organization GO:0007033 39 24 0,000 0,17674053 0,21349959 ! neural crest cell development GO:0014032 39 24 0,000 0,17674053 0,21338752 GO:0014033|neural crest cell differentiation, ! primary neural tube formation GO:0014020 35 24 0,000 0,17674053 0,21327556 ! regulation of alpha-beta T cell activation GO:0046634 35 24 0,000 0,17674053 0,21316372 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,17674053 0,213052 GO:0002708|positive regulation of lymphocyte mediated immunity, ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 0,000 0,17674053 0,2129404 ! regulation of oxidoreductase activity GO:0051341 39 24 0,000 0,17674053 0,21282891 ! glutathione metabolic process GO:0006749 29 24 0,000 0,17674053 0,21271754 ! regulation of osteoblast differentiation GO:0045667 37 24 0,000 0,17674053 0,21260629 ! neurotransmitter secretion GO:0007269 32 24 0,000 0,17674053 0,21249515 ! regulation of JUN kinase activity GO:0043506 34 24 0,000 0,17674053 0,21238413 ! regulation of binding GO:0051098 151 95 1,000 0,17854177 0,21443659 ! carboxylic acid transport GO:0046942 147 95 1,000 0,17854177 0,21432467 GO:0015849|organic acid transport, ! regulation of response to external stimulus GO:0032101 139 96 1,000 0,18143321 0,21768199 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 1,000 0,18143321 0,2175685 ! protein maturation GO:0051604 129 96 1,000 0,18143321 0,21745512 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,18338961 0,21968547 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,18338961 0,21957111 GO:0006479|protein amino acid methylation, ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,18338961 0,21945686 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,18338961 0,21934274 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 0,000 0,18338961 0,21922874 GO:0045936|negative regulation of phosphate metabolic process, ! peptide transport GO:0015833 43 25 0,000 0,18338961 0,21911485 ! male gonad development GO:0008584 33 25 0,000 0,18338961 0,21900109 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,18338961 0,21888744 ! phospholipid transport GO:0015914 35 25 0,000 0,18338961 0,21877391 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,18338961 0,21866049 ! positive regulation of MAPKKK cascade GO:0043410 36 25 0,000 0,18338961 0,2185472 ! detection of light stimulus GO:0009583 30 25 0,000 0,18338961 0,21843402 ! positive regulation of nuclear division GO:0051785 39 25 0,000 0,18338961 0,21832096 GO:0045840|positive regulation of mitosis, ! peptidyl-tyrosine modification GO:0018212 37 25 0,000 0,18338961 0,21820802 ! leukocyte proliferation GO:0070661 39 25 0,000 0,18338961 0,21809519 GO:0032943|mononuclear cell proliferation, ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,18998536 0,22582239 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 0,000 0,18998536 0,22570575 ! translational initiation GO:0006413 43 26 0,000 0,18998536 0,22558922 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 0,000 0,18998536 0,22547282 ! circadian rhythm GO:0007623 42 26 0,000 0,18998536 0,22535654 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,18998536 0,22524037 ! post-embryonic development GO:0009791 42 26 0,000 0,18998536 0,22512433 ! negative regulation of protein modification process GO:0031400 50 26 0,000 0,18998536 0,22500841 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,18998536 0,2248926 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,18998536 0,22477692 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 0,000 0,18998536 0,22466135 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,18998536 0,2245459 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,18998536 0,22443057 ! regulation of coagulation GO:0050818 39 26 0,000 0,18998536 0,22431536 ! protein import GO:0017038 156 99 1,000 0,1901488 0,22439314 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 1,000 0,1901488 0,22427807 ! regulation of translation GO:0006417 151 100 1,000 0,19306676 0,22760305 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 1,000 0,19306676 0,22748645 ! regulation of body fluid levels GO:0050878 154 100 1,000 0,19306676 0,22736997 ! protein localization in organelle GO:0033365 161 100 1,000 0,19306676 0,22725361 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,19652821 0,23120966 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,19652821 0,23109146 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,19652821 0,23097337 ! membrane docking GO:0022406 39 27 0,000 0,19652821 0,23085541 ! inner ear morphogenesis GO:0042472 35 27 0,000 0,19652821 0,23073757 ! acute-phase response GO:0006953 42 27 0,000 0,19652821 0,23061984 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,19652821 0,23050224 ! myofibril assembly GO:0030239 36 27 0,000 0,19652821 0,23038476 GO:0055002|striated muscle cell development, ! respiratory gaseous exchange GO:0007585 47 27 0,000 0,19652821 0,23026739 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 0,000 0,19652821 0,23015015 ! natural killer cell activation GO:0030101 35 27 0,000 0,19652821 0,23003302 ! lipid oxidation GO:0034440 38 27 0,000 0,19652821 0,22991602 GO:0019395|fatty acid oxidation, ! cofactor catabolic process GO:0051187 45 27 0,000 0,19652821 0,22979913 ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,19652821 0,22968236 ! negative regulation of neuron apoptosis GO:0043524 42 27 0,000 0,19652821 0,22956571 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 0,000 0,20301859 0,23702678 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,20301859 0,23690652 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,20301859 0,23678639 ! cell junction assembly GO:0034329 56 28 0,000 0,20301859 0,23666637 ! positive regulation of endocytosis GO:0045807 33 28 0,000 0,20301859 0,23654648 ! cholesterol homeostasis GO:0042632 46 28 0,000 0,20301859 0,23642671 GO:0055092|sterol homeostasis, ! complement activation, classical pathway GO:0006958 36 28 0,000 0,20301859 0,23630706 ! triglyceride metabolic process GO:0006641 34 28 0,000 0,20301859 0,23618754 ! erythrocyte differentiation GO:0030218 38 28 0,000 0,20301859 0,23606813 ! immune response-activating signal transduction GO:0002757 38 28 0,000 0,20301859 0,23594884 GO:0002764|immune response-regulating signal transduction, ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,20301859 0,23582968 ! positive regulation of T cell differentiation GO:0045582 39 28 0,000 0,20301859 0,23571063 ! mesoderm formation GO:0001707 46 28 0,000 0,20301859 0,2355917 ! positive regulation of multicellular organism growth GO:0040018 38 28 0,000 0,20301859 0,2354729 ! negative regulation of MAP kinase activity GO:0043407 54 28 0,000 0,20301859 0,23535421 ! BMP signaling pathway GO:0030509 40 28 0,000 0,20301859 0,23523565 ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,20301859 0,2351172 ! myeloid leukocyte activation GO:0002274 39 28 0,000 0,20301859 0,23499887 ! neural tube formation GO:0001841 41 28 0,000 0,20301859 0,23488066 ! regulation of B cell activation GO:0050864 42 28 0,000 0,20301859 0,23476257 ! regulation of innate immune response GO:0045088 38 29 0,000 0,20945691 0,24208587 ! ovulation cycle process GO:0022602 41 29 0,000 0,20945691 0,24196428 ! positive regulation of T cell proliferation GO:0042102 44 29 0,000 0,20945691 0,24184281 ! protein targeting to membrane GO:0006612 53 29 0,000 0,20945691 0,24172147 ! regulation of axonogenesis GO:0050770 51 29 0,000 0,20945691 0,24160024 ! muscle cell development GO:0055001 38 29 0,000 0,20945691 0,24147914 ! formation of primary germ layer GO:0001704 48 29 0,000 0,20945691 0,24135816 ! telencephalon development GO:0021537 52 29 0,000 0,20945691 0,2412373 ! hexose biosynthetic process GO:0019319 35 29 0,000 0,20945691 0,24111656 ! eye morphogenesis GO:0048592 51 29 0,000 0,20945691 0,24099594 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,20945691 0,24087544 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 0,000 0,21584358 0,24809607 ! collagen metabolic process GO:0032963 40 30 0,000 0,21584358 0,24797214 ! organic anion transport GO:0015711 51 30 0,000 0,21584358 0,24784834 ! cholesterol transport GO:0030301 46 30 0,000 0,21584358 0,24772467 GO:0015918|sterol transport, ! embryonic skeletal system morphogenesis GO:0048704 42 30 0,000 0,21584358 0,24760111 ! spliceosome assembly GO:0000245 49 30 0,000 0,21584358 0,24747768 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,21584358 0,24735437 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,21584358 0,24723119 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,21584358 0,24710813 ! ceramide metabolic process GO:0006672 43 30 0,000 0,21584358 0,24698519 ! ovulation cycle GO:0042698 43 30 0,000 0,21584358 0,24686237 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,21584358 0,24673968 ! embryonic epithelial tube formation GO:0001838 44 30 0,000 0,21584358 0,2466171 ! regulation of microtubule-based process GO:0032886 58 30 0,000 0,21584358 0,24649465 ! response to heat GO:0009408 41 30 0,000 0,21584358 0,24637232 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,21584358 0,24625011 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,21584358 0,24612803 ! negative regulation of secretion GO:0051048 49 31 0,000 0,22217902 0,25322683 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 0,000 0,22217902 0,2531014 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,22217902 0,25297611 ! odontogenesis GO:0042476 50 31 0,000 0,22217902 0,25285093 ! segmentation GO:0035282 41 31 0,000 0,22217902 0,25272588 ! regulation of striated muscle tissue development GO:0016202 47 31 0,000 0,22217902 0,25260096 ! mesoderm morphogenesis GO:0048332 49 31 0,000 0,22217902 0,25247615 ! metanephros development GO:0001656 58 31 0,000 0,22217902 0,25235147 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,22217902 0,25222692 ! cell fate specification GO:0001708 37 31 0,000 0,22217902 0,25210248 ! leukocyte chemotaxis GO:0030595 43 31 0,000 0,22217902 0,25197817 GO:0060326|cell chemotaxis, ! biogenic amine biosynthetic process GO:0042401 44 31 0,000 0,22217902 0,25185399 ! RNA modification GO:0009451 40 31 0,000 0,22217902 0,25172992 ! regulation of muscle development GO:0048634 48 32 0,000 0,22846363 0,25872297 ! mitotic sister chromatid segregation GO:0000070 45 32 0,000 0,22846363 0,25859564 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 0,000 0,22846363 0,25846844 ! regulation of synaptic plasticity GO:0048167 52 32 0,000 0,22846363 0,25834137 ! regulation of ARF protein signal transduction GO:0032012 51 32 0,000 0,22846363 0,25821442 ! neutral lipid metabolic process GO:0006638 41 32 0,000 0,22846363 0,25808759 GO:0006639|acylglycerol metabolic process, ! calcium-mediated signaling GO:0019722 50 32 0,000 0,22846363 0,2579609 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 0,000 0,22846363 0,25783432 ! cytokine production GO:0001816 44 32 0,000 0,22846363 0,25770787 ! monosaccharide biosynthetic process GO:0046364 38 32 0,000 0,22846363 0,25758154 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 0,000 0,22846363 0,25745534 ! vesicle localization GO:0051648 47 32 0,000 0,22846363 0,25732926 ! RNA export from nucleus GO:0006405 44 33 0,000 0,23469782 0,26422172 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,23469782 0,26409246 ! sister chromatid segregation GO:0000819 46 33 0,000 0,23469782 0,26396332 ! actomyosin structure organization GO:0031032 43 33 0,000 0,23469782 0,2638343 ! cell junction organization GO:0034330 63 33 0,000 0,23469782 0,26370541 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,23469782 0,26357665 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,23469782 0,26344801 ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 0,000 0,23469782 0,2633195 ! positive regulation of cell development GO:0010720 54 33 0,000 0,23469782 0,26319112 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,23469782 0,26306286 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,23469782 0,26293472 ! androgen receptor signaling pathway GO:0030521 54 33 0,000 0,23469782 0,26280671 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,23469782 0,26267882 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 0,000 0,24088199 0,26946915 ! regulation of neuron projection development GO:0010975 63 34 0,000 0,24088199 0,26933815 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 0,000 0,24088199 0,26920728 ! establishment or maintenance of cell polarity GO:0007163 61 34 0,000 0,24088199 0,26907653 ! development of primary male sexual characteristics GO:0046546 44 34 0,000 0,24088199 0,26894591 ! glycerol ether metabolic process GO:0006662 44 34 0,000 0,24088199 0,26881542 ! erythrocyte homeostasis GO:0034101 45 34 0,000 0,24088199 0,26868505 ! neuron migration GO:0001764 46 34 0,000 0,24088199 0,26855481 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,24088199 0,2684247 ! aerobic respiration GO:0009060 47 34 0,000 0,24088199 0,26829471 ! dorsal/ventral pattern formation GO:0009953 44 34 0,000 0,24088199 0,26816485 ! embryonic organ development GO:0048568 45 34 0,000 0,24088199 0,26803511 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 0,000 0,24088199 0,2679055 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,24701654 0,27459548 ! Notch signaling pathway GO:0007219 56 35 0,000 0,24701654 0,27446282 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,24701654 0,2743303 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,24701654 0,2741979 GO:0032313|regulation of Rab GTPase activity, ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,24701654 0,27406563 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,24701654 0,27393348 GO:0015986|ATP synthesis coupled proton transport, ! Rho protein signal transduction GO:0007266 51 35 0,000 0,24701654 0,27380147 ! pigment metabolic process GO:0042440 61 35 0,000 0,24701654 0,27366958 ! positive regulation of leukocyte proliferation GO:0070665 50 35 0,000 0,24701654 0,27353782 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! positive regulation of transcription factor activity GO:0051091 49 36 0,000 0,25310187 0,28014162 GO:0090047|positive regulation of transcription regulator activity, ! cellular amide metabolic process GO:0043603 52 36 0,000 0,25310187 0,28000687 ! organic ether metabolic process GO:0018904 46 36 0,000 0,25310187 0,27987226 ! tissue remodeling GO:0048771 62 36 0,000 0,25310187 0,27973777 ! neural tube development GO:0021915 50 36 0,000 0,25310187 0,27960341 ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,25310187 0,27946917 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 0,000 0,25913836 0,28599723 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,25913836 0,28586006 GO:0006956|complement activation, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,25913836 0,28572302 ! learning GO:0007612 67 37 0,000 0,25913836 0,28558611 ! ion transmembrane transport GO:0034220 56 37 0,000 0,25913836 0,28544934 ! ribonucleoside metabolic process GO:0009119 48 37 0,000 0,25913836 0,2853127 ! regulation of protein secretion GO:0050708 51 37 0,000 0,25913836 0,28517618 ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,25913836 0,2850398 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 0,000 0,26512641 0,29148697 ! striated muscle cell differentiation GO:0051146 54 38 0,000 0,26512641 0,2913477 ! alcohol biosynthetic process GO:0046165 45 38 0,000 0,26512641 0,29120856 ! phagocytosis GO:0006909 60 38 0,000 0,26512641 0,29106956 ! mesenchymal cell development GO:0014031 64 38 0,000 0,26512641 0,29093069 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 0,000 0,27106639 0,29730697 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,27106639 0,29716526 ! morphogenesis of embryonic epithelium GO:0016331 60 39 0,000 0,27106639 0,29702368 ! multicellular organismal metabolic process GO:0044236 50 39 0,000 0,27106639 0,29688224 ! male sex differentiation GO:0046661 53 39 0,000 0,27106639 0,29674094 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 0,000 0,27106639 0,29659977 ! chromatin remodeling GO:0006338 68 39 0,000 0,27106639 0,29645873 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,27106639 0,29631783 ! JNK cascade GO:0007254 54 39 0,000 0,27106639 0,29617706 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 0,000 0,27695871 0,30247152 ! regulation of tube size GO:0035150 60 40 0,000 0,27695871 0,30232797 GO:0050880|regulation of blood vessel size, ! positive regulation of response to external stimulus GO:0032103 65 40 0,000 0,27695871 0,30218455 ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 0,000 0,27695871 0,30204127 ! peptide metabolic process GO:0006518 56 40 0,000 0,27695871 0,30189812 ! inner ear development GO:0048839 57 40 0,000 0,27695871 0,30175511 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,27695871 0,30161223 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! JAK-STAT cascade GO:0007259 53 40 0,000 0,27695871 0,30146949 ! glucose transport GO:0015758 52 41 0,000 0,28280373 0,30768618 ! striated muscle contraction GO:0006941 62 41 0,000 0,28280373 0,3075407 ! positive regulation of DNA binding GO:0043388 57 41 0,000 0,28280373 0,30739536 ! regulation of leukocyte mediated immunity GO:0002703 62 41 0,000 0,28280373 0,30725015 ! biopolymer methylation GO:0043414 62 41 0,000 0,28280373 0,30710509 ! regulation of JNK cascade GO:0046328 58 41 0,000 0,28280373 0,30696016 ! receptor-mediated endocytosis GO:0006898 76 42 0,000 0,28860183 0,31310576 ! regulation of JAK-STAT cascade GO:0046425 61 42 0,000 0,28860183 0,31295814 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 0,000 0,28860183 0,31281065 ! hexose transport GO:0008645 54 42 0,000 0,28860183 0,31266331 GO:0015749|monosaccharide transport, ! embryonic skeletal system development GO:0048706 56 42 0,000 0,28860183 0,3125161 ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,28860183 0,31236904 ! excretion GO:0007588 63 42 0,000 0,28860183 0,31222211 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,28860183 0,31207532 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,28860183 0,31192867 ! positive regulation of binding GO:0051099 59 43 0,000 0,29435338 0,31799567 ! leukocyte migration GO:0050900 60 43 0,000 0,29435338 0,31784638 ! neuromuscular process GO:0050905 79 43 0,000 0,29435338 0,31769722 ! tRNA processing GO:0008033 49 43 0,000 0,29435338 0,31754821 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 0,000 0,29435338 0,31739934 ! vesicle organization GO:0016050 79 43 0,000 0,29435338 0,3172506 ! epithelial tube morphogenesis GO:0060562 65 43 0,000 0,29435338 0,31710201 ! methylation GO:0032259 64 43 0,000 0,29435338 0,31695355 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,30005877 0,3229458 ! regulation of cell projection organization GO:0031344 83 44 0,000 0,30005877 0,32279475 ! regulation of ion transport GO:0043269 57 44 0,000 0,30005877 0,32264384 ! cellular amino acid biosynthetic process GO:0008652 51 44 0,000 0,30005877 0,32249307 ! induction of apoptosis by extracellular signals GO:0008624 74 44 0,000 0,30005877 0,32234244 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 0,000 0,30005877 0,32219195 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,30005877 0,32204161 ! regulation of inflammatory response GO:0050727 60 44 0,000 0,30005877 0,3218914 ! positive regulation of defense response GO:0031349 59 45 0,000 0,30571835 0,32780988 ! regulation of translational initiation GO:0006446 64 45 0,000 0,30571835 0,32765713 ! vascular process in circulatory system GO:0003018 69 45 0,000 0,30571835 0,32750452 ! cell recognition GO:0008037 58 45 0,000 0,30571835 0,32735205 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,31133248 0,33320833 ! cell redox homeostasis GO:0045454 63 46 0,000 0,31133248 0,33305335 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,31133248 0,33289852 ! regulation of ossification GO:0030278 71 46 0,000 0,31133248 0,33274382 ! regulation of adaptive immune response GO:0002819 72 46 0,000 0,31133248 0,33258928 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,31690154 0,33838141 ! viral infectious cycle GO:0019058 71 47 0,000 0,31690154 0,33822438 ! endocrine system development GO:0035270 83 47 0,000 0,31690154 0,33806751 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,31690154 0,33791078 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,31690154 0,33775419 ! chloride transport GO:0006821 67 48 0,000 0,32242588 0,34348288 ! regulation of muscle contraction GO:0006937 69 48 0,000 0,32242588 0,34332386 ! response to temperature stimulus GO:0009266 62 48 0,000 0,32242588 0,34316498 ! gastrulation GO:0007369 73 48 0,000 0,32242588 0,34300626 ! heart morphogenesis GO:0003007 65 48 0,000 0,32242588 0,34284768 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 0,000 0,32242588 0,34268925 ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,32242588 0,34253096 ! regulation of endocytosis GO:0030100 63 48 0,000 0,32242588 0,34237282 ! nuclear export GO:0051168 69 48 0,000 0,32242588 0,34221483 ! positive regulation of cytokine production GO:0001819 73 48 0,000 0,32242588 0,34205698 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,32790586 0,34771023 ! sensory perception of smell GO:0007608 61 49 0,000 0,32790586 0,34754999 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,32790586 0,3473899 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,32790586 0,34722996 ! heterocycle catabolic process GO:0046700 72 49 0,000 0,32790586 0,34707017 ! integrin-mediated signaling pathway GO:0007229 81 49 0,000 0,32790586 0,34691053 ! cartilage development GO:0051216 70 49 0,000 0,32790586 0,34675103 ! positive regulation of growth GO:0045927 67 50 0,000 0,33334183 0,35233741 ! proton transport GO:0015992 75 50 0,000 0,33334183 0,35217557 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 0,000 0,33334183 0,35201387 ! positive regulation of secretion GO:0051047 71 51 0,000 0,33873415 0,35754407 ! hydrogen transport GO:0006818 77 51 0,000 0,33873415 0,35738006 ! activation of phospholipase C activity GO:0007202 87 51 0,000 0,33873415 0,3572162 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of cell migration GO:0030335 92 51 0,000 0,33873415 0,35705249 ! positive regulation of organelle organization GO:0010638 82 51 0,000 0,33873415 0,35688893 ! transition metal ion transport GO:0000041 74 52 0,000 0,34408315 0,36235863 ! positive regulation of phospholipase activity GO:0010518 88 52 0,000 0,34408315 0,36219279 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,34408315 0,3620271 ! regulation of bone remodeling GO:0046850 90 53 0,000 0,34938919 0,36744176 ! kidney development GO:0001822 90 53 0,000 0,34938919 0,36727383 ! single fertilization GO:0007338 59 53 0,000 0,34938919 0,36710605 ! cell projection assembly GO:0030031 76 53 0,000 0,34938919 0,36693842 ! amino acid transport GO:0006865 84 54 0,000 0,35465261 0,37229621 ! regulation of mitosis GO:0007088 84 54 0,000 0,35465261 0,37212637 GO:0051783|regulation of nuclear division, ! regulation of phospholipase activity GO:0010517 90 54 0,000 0,35465261 0,37195668 ! cytokine-mediated signaling pathway GO:0019221 76 54 0,000 0,35465261 0,37178715 ! regulation of tissue remodeling GO:0034103 91 54 0,000 0,35465261 0,37161777 ! cellular amino acid catabolic process GO:0009063 74 54 0,000 0,35465261 0,37144854 ! positive regulation of lipase activity GO:0060193 90 54 0,000 0,35465261 0,37127947 ! exocytosis GO:0006887 74 55 0,000 0,35987375 0,37657398 ! mesoderm development GO:0007498 76 55 0,000 0,35987375 0,37640273 ! nucleoside metabolic process GO:0009116 69 55 0,000 0,35987375 0,37623164 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,35987375 0,37606071 ! positive regulation of cell motion GO:0051272 99 56 0,000 0,36505294 0,38129962 ! negative regulation of protein kinase activity GO:0006469 99 57 0,000 0,37019052 0,38649033 ! carbohydrate transport GO:0008643 74 57 0,000 0,37019052 0,38631497 ! multicellular organism reproduction GO:0032504 83 57 0,000 0,37019052 0,38613977 GO:0048609|reproductive process in a multicellular organism, ! coenzyme biosynthetic process GO:0009108 67 57 0,000 0,37019052 0,38596473 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,37019052 0,38578985 ! camera-type eye development GO:0043010 88 57 0,000 0,37019052 0,38561513 ! secondary metabolic process GO:0019748 84 57 0,000 0,37019052 0,38544056 ! negative regulation of kinase activity GO:0033673 100 58 0,000 0,37528683 0,39057 ! viral reproductive process GO:0022415 87 58 0,000 0,37528683 0,39039335 ! regulation of cytokine biosynthetic process GO:0042035 76 58 0,000 0,37528683 0,39021687 ! steroid hormone receptor signaling pathway GO:0030518 96 58 0,000 0,37528683 0,39004054 ! protein maturation by peptide bond cleavage GO:0051605 76 58 0,000 0,37528683 0,38986437 ! activation of MAPK activity GO:0000187 84 59 0,000 0,38034219 0,39493771 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,38034219 0,39475949 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 0,000 0,38535692 0,39978391 ! regulation of heart contraction GO:0008016 91 60 0,000 0,38535692 0,39960366 ! regulation of vesicle-mediated transport GO:0060627 79 60 0,000 0,38535692 0,39942358 ! fertilization GO:0009566 68 60 0,000 0,38535692 0,39924366 ! regulation of cellular response to stress GO:0080135 85 61 0,000 0,39033136 0,40421528 ! cell-matrix adhesion GO:0007160 114 61 0,000 0,39033136 0,40403336 ! homeostasis of number of cells GO:0048872 84 61 0,000 0,39033136 0,40385161 ! negative regulation of ligase activity GO:0051352 91 61 0,000 0,39033136 0,40367002 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! negative regulation of transferase activity GO:0051348 105 61 0,000 0,39033136 0,4034886 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 0,000 0,39033136 0,40330734 ! amine catabolic process GO:0009310 90 62 0,000 0,39526582 0,40822245 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,39526582 0,40803923 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 0,000 0,39526582 0,40785617 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 0,000 0,40016063 0,41272173 ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 0,000 0,40016063 0,41253673 ! viral reproduction GO:0016032 92 63 0,000 0,40016063 0,4123519 ! regulation of lipase activity GO:0060191 109 63 0,000 0,40016063 0,41216724 ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,4050161 0,41698166 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 0,000 0,40983253 0,4217516 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 0,000 0,40983253 0,42156298 ! defense response to bacterium GO:0042742 73 65 0,000 0,40983253 0,42137453 ! regulation of MAPKKK cascade GO:0043408 101 65 0,000 0,40983253 0,42118625 ! positive regulation of T cell activation GO:0050870 94 65 0,000 0,40983253 0,42099814 ! activation of immune response GO:0002253 83 65 0,000 0,40983253 0,42081019 ! cell-substrate adhesion GO:0031589 121 66 0,000 0,41461026 0,42552592 ! antigen processing and presentation GO:0019882 96 66 0,000 0,41461026 0,42533613 ! regulation of Rho protein signal transduction GO:0035023 111 66 0,000 0,41461026 0,4251465 ! regulation of immune effector process GO:0002697 101 66 0,000 0,41461026 0,42495704 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,41934958 0,42962317 ! regulation of neuron differentiation GO:0045664 107 67 0,000 0,41934958 0,42943189 ! acute inflammatory response GO:0002526 92 68 0,000 0,42405079 0,43405288 ! learning or memory GO:0007611 123 68 0,000 0,42405079 0,4338598 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,42405079 0,43366689 ! regulation of Ras GTPase activity GO:0032318 110 68 0,000 0,42405079 0,43347414 ! inorganic anion transport GO:0015698 93 68 0,000 0,42405079 0,43328158 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,42871422 0,437852 ! activation of protein kinase activity GO:0032147 102 69 0,000 0,42871422 0,43765766 ! positive regulation of ligase activity GO:0051351 99 69 0,000 0,42871422 0,43746349 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 0,000 0,43334014 0,44198773 ! humoral immune response GO:0006959 86 70 0,000 0,43334014 0,44179181 ! muscle cell differentiation GO:0042692 104 71 0,000 0,43792888 0,44627223 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 0,000 0,43792888 0,44607459 ! response to hypoxia GO:0001666 132 72 0,000 0,44248072 0,45051157 ! cellular lipid catabolic process GO:0044242 105 73 0,000 0,44699595 0,45490738 ! response to oxygen levels GO:0070482 137 74 0,000 0,45147487 0,45926236 ! digestion GO:0007586 97 74 0,000 0,45147487 0,45905933 ! positive regulation of lymphocyte activation GO:0051251 108 74 0,000 0,45147487 0,45885648 ! regulation of ligase activity GO:0051340 114 75 0,000 0,45591777 0,46316735 ! cofactor biosynthetic process GO:0051188 92 75 0,000 0,45591777 0,46296286 ! amine biosynthetic process GO:0009309 97 76 0,000 0,46032494 0,46723185 ! one-carbon metabolic process GO:0006730 110 77 0,000 0,46469667 0,47146111 ! carbohydrate biosynthetic process GO:0016051 97 77 0,000 0,46469667 0,47125323 ! nitrogen compound catabolic process GO:0044270 114 78 0,000 0,46903322 0,47544134 ! cellular respiration GO:0045333 107 79 0,000 0,47333489 0,47959042 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,47333489 0,47937924 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,47333489 0,47916825 ! chromatin assembly GO:0031497 102 80 0,000 0,47760196 0,48327519 GO:0006334|nucleosome assembly, ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 0,000 0,47760196 0,48306267 GO:0010498|proteasomal protein catabolic process, ! regulation of GTPase activity GO:0043087 129 80 0,000 0,47760196 0,48285034 ! vitamin metabolic process GO:0006766 103 81 0,000 0,4818347 0,48691556 ! positive regulation of cell activation GO:0050867 120 81 0,000 0,4818347 0,48670172 GO:0002696|positive regulation of leukocyte activation, ! ossification GO:0001503 134 82 0,000 0,48603339 0,4907273 GO:0060348|bone development, ! regulation of defense response GO:0031347 117 84 0,000 0,49432968 0,49888471 ! protein-DNA complex assembly GO:0065004 107 84 0,000 0,49432968 0,4986659 ! Golgi vesicle transport GO:0048193 138 85 0,000 0,49842782 0,50257957 ! anterior/posterior pattern formation GO:0009952 124 85 0,000 0,49842782 0,50235933 ! negative regulation of multicellular organismal process GO:0051241 133 85 0,000 0,49842782 0,50213929 ! nucleosome organization GO:0034728 114 87 0,000 0,50652544 0,51007378 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 0,000 0,50652544 0,50985055 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cellular defense response GO:0006968 102 87 0,000 0,50652544 0,50962752 ! female pregnancy GO:0007565 130 87 0,000 0,50652544 0,50940468 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 0,000 0,51052543 0,51320301 ! carboxylic acid catabolic process GO:0046395 122 88 0,000 0,51052543 0,51297881 GO:0016054|organic acid catabolic process, ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 0,000 0,51449323 0,51673993 ! ATP metabolic process GO:0046034 137 91 0,000 0,52233327 0,52438522 ! response to virus GO:0009615 122 91 0,000 0,52233327 0,52415643 ! positive regulation of immune response GO:0050778 121 92 0,000 0,52620602 0,52781241 ! sulfur metabolic process GO:0006790 118 92 0,000 0,52620602 0,52758233 ! electron transport chain GO:0022900 123 94 0,000 0,53385824 0,53502133 ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,54510706 0,54605673 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! calcium ion transport GO:0006816 167 99 0,000 0,55245611 0,55317765 ! homophilic cell adhesion GO:0007156 149 100 0,000 0,55608631 0,55657028 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 0,000 0,55608631 0,55632819 ! divalent metal ion transport GO:0070838 171 100 0,000 0,55608631 0,55608631