pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6731-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! phospholipid dephosphorylation GO:0046839 12 5 3,000 7,965E-09 1,916E-05 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 3,000 2,378E-08 2,86E-05 ! negative regulation of focal adhesion formation GO:0051895 20 7 3,000 5,52E-08 4,427E-05 ! regulation of focal adhesion formation GO:0051893 22 8 3,000 1,098E-07 6,607E-05 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 3,000 3,263E-07 1,57E-04 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 3,000 3,263E-07 1,308E-04 ! induction of apoptosis by intracellular signals GO:0008629 93 45 5,000 4,112E-07 1,413E-04 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 4,000 4,788E-07 1,44E-04 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 3,000 5,101E-07 1,364E-04 GO:0010812|negative regulation of cell-substrate adhesion, ! regulation of DNA metabolic process GO:0051052 178 97 6,000 3,036E-06 7,305E-04 ! endothelial cell migration GO:0043542 28 17 3,000 3,57E-06 7,81E-04 ! inositol metabolic process GO:0006020 28 17 3,000 3,57E-06 7,159E-04 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 3,000 3,57E-06 6,608E-04 ! cardiac muscle tissue development GO:0048738 31 17 3,000 3,57E-06 6,136E-04 ! regulation of protein stability GO:0031647 73 37 4,000 3,692E-06 5,921E-04 ! male meiosis GO:0007140 7 6 2,000 5,03E-06 7,564E-04 ! hormone-mediated signaling GO:0009755 74 41 4,000 6,217E-06 8,798E-04 ! apoptotic mitochondrial changes GO:0008637 41 20 3,000 7,16E-06 9,571E-04 ! meiosis GO:0007126 121 74 5,000 8,023E-06 1,016E-03 GO:0051327|M phase of meiotic cell cycle, ! meiotic cell cycle GO:0051321 122 75 5,000 8,674E-06 1,044E-03 ! prostate gland development GO:0030850 13 7 2,000 8,761E-06 1,004E-03 ! regulation of protein export from nucleus GO:0046825 10 7 2,000 8,761E-06 9,582E-04 ! G1 DNA damage checkpoint GO:0031571 21 7 2,000 8,761E-06 9,165E-04 ! double-strand break repair GO:0006302 81 44 4,000 8,871E-06 8,893E-04 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 3,000 1,07E-05 1,03E-03 ! regulation of cell-matrix adhesion GO:0001952 78 23 3,000 1,289E-05 1,193E-03 GO:0010810|regulation of cell-substrate adhesion, ! ER overload response GO:0006983 12 8 2,000 1,395E-05 1,243E-03 ! blastocyst growth GO:0001832 19 8 2,000 1,395E-05 1,199E-03 ! cellular response to hormone stimulus GO:0032870 167 82 5,000 1,454E-05 1,206E-03 ! response to endoplasmic reticulum stress GO:0034976 43 25 3,000 1,823E-05 1,462E-03 ! ER-nuclear signaling pathway GO:0006984 48 28 3,000 2,908E-05 2,257E-03 ! protein sumoylation GO:0016925 15 10 2,000 2,962E-05 2,227E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 4,000 3,198E-05 2,332E-03 ! negative regulation of protein kinase cascade GO:0010741 68 30 3,000 3,853E-05 2,727E-03 ! DNA damage response, signal transduction GO:0042770 128 60 4,000 4,108E-05 2,824E-03 ! double-strand break repair via homologous recombination GO:0000724 19 13 2,000 6,96E-05 4,651E-03 GO:0000725|recombinational repair, ! response to X-ray GO:0010165 25 13 2,000 6,96E-05 4,526E-03 ! negative regulation of DNA metabolic process GO:0051053 61 35 3,000 7,181E-05 4,547E-03 ! negative regulation of cell adhesion GO:0007162 81 35 3,000 7,181E-05 4,43E-03 ! response to gamma radiation GO:0010332 28 14 2,000 8,816E-05 5,303E-03 ! oxygen transport GO:0015671 21 14 2,000 8,816E-05 5,174E-03 ! release of cytochrome c from mitochondria GO:0001836 30 14 2,000 8,816E-05 5,051E-03 ! phosphoinositide metabolic process GO:0030384 128 72 4,000 9,892E-05 5,535E-03 ! G1/S transition checkpoint GO:0031575 40 15 2,000 1,097E-04 5,998E-03 ! fructose metabolic process GO:0006000 25 16 2,000 1,344E-04 7,184E-03 ! polyol metabolic process GO:0019751 66 41 3,000 1,348E-04 7,05E-03 ! regulation of intracellular protein transport GO:0033157 80 42 3,000 1,482E-04 7,589E-03 ! gas transport GO:0015669 25 17 2,000 1,624E-04 8,14E-03 ! energy reserve metabolic process GO:0006112 74 43 3,000 1,626E-04 7,986E-03 ! glycolysis GO:0006096 65 45 3,000 1,944E-04 9,355E-03 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 3,000 2,119E-04 9,996E-03 ! negative regulation of cell migration GO:0030336 115 46 3,000 2,119E-04 9,803E-03 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 2,000 2,292E-04 0,01040701 ! gland development GO:0048732 206 88 4,000 2,551E-04 0,01136697 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 2,000 2,684E-04 0,01174304 ! regulation of cell adhesion GO:0030155 212 89 4,000 2,689E-04 0,01155398 ! reciprocal meiotic recombination GO:0007131 39 21 2,000 3,117E-04 0,01315759 ! cell aging GO:0007569 44 21 2,000 3,117E-04 0,01293073 ! oogenesis GO:0048477 36 21 2,000 3,117E-04 0,01271157 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 3,000 3,165E-04 0,01269212 ! transcription initiation GO:0006352 153 94 4,000 3,466E-04 0,01367164 ! apoptotic nuclear changes GO:0030262 32 22 2,000 3,592E-04 0,01394088 ! positive regulation of intracellular transport GO:0032388 37 22 2,000 3,592E-04 0,0137196 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 3,000 3,672E-04 0,01380503 ! cell maturation GO:0048469 100 53 3,000 3,672E-04 0,01359264 ! response to UV GO:0009411 104 53 3,000 3,672E-04 0,01338669 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 1,000 3,992E-04 0,01433698 ! glial cell fate commitment GO:0021781 13 5 1,000 3,992E-04 0,01412614 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 1,000 3,992E-04 0,01392141 ! positive regulation of viral genome replication GO:0045070 9 5 1,000 3,992E-04 0,01372253 ! regulation of retroviral genome replication GO:0045091 7 5 1,000 3,992E-04 0,01352926 ! negative regulation of survival gene product expression GO:0008634 8 5 1,000 3,992E-04 0,01334135 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 1,000 3,992E-04 0,01315859 ! regulation of response to food GO:0032095 7 5 1,000 3,992E-04 0,01298078 ! early endosome to late endosome transport GO:0045022 12 5 1,000 3,992E-04 0,0128077 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 1,000 3,992E-04 0,01263918 ! meiotic chromosome segregation GO:0045132 7 5 1,000 3,992E-04 0,01247503 ! mitotic recombination GO:0006312 9 5 1,000 3,992E-04 0,0123151 ! metaphase plate congression GO:0051310 7 5 1,000 3,992E-04 0,01215921 ! regulation of sterol transport GO:0032371 7 5 1,000 3,992E-04 0,01200722 GO:0032374|regulation of cholesterol transport, ! inner cell mass cell proliferation GO:0001833 5 5 1,000 3,992E-04 0,01185898 ! spindle assembly GO:0051225 6 5 1,000 3,992E-04 0,01171436 ! receptor biosynthetic process GO:0032800 7 5 1,000 3,992E-04 0,01157322 ! glucose catabolic process GO:0006007 82 55 3,000 4,235E-04 0,01212958 ! regulation of protein catabolic process GO:0042176 116 55 3,000 4,235E-04 0,01198688 ! RNA elongation GO:0006354 79 55 3,000 4,235E-04 0,01184749 ! negative regulation of cell motion GO:0051271 134 55 3,000 4,235E-04 0,01171131 ! regulation of actin filament length GO:0030832 105 56 3,000 4,538E-04 0,01240719 ! nucleotide-excision repair GO:0006289 83 56 3,000 4,538E-04 0,01226778 ! regulation of DNA replication GO:0006275 101 56 3,000 4,538E-04 0,01213147 ! lipid modification GO:0030258 97 57 3,000 4,856E-04 0,01283986 ! regulation of intracellular transport GO:0032386 101 57 3,000 4,856E-04 0,0127003 ! negative regulation of DNA replication GO:0008156 42 25 2,000 5,29E-04 0,01368658 ! receptor metabolic process GO:0043112 46 25 2,000 5,29E-04 0,01354097 ! regulation of cellular component size GO:0032535 109 59 3,000 5,54E-04 0,01403126 ! regulation of cellular ketone metabolic process GO:0010565 44 26 2,000 5,952E-04 0,01491819 ! blastocyst development GO:0001824 49 26 2,000 5,952E-04 0,0147644 ! positive regulation of actin filament polymerization GO:0030838 11 6 1,000 5,963E-04 0,01464097 ! regulation of appetite GO:0032098 9 6 1,000 5,963E-04 0,01449308 ! attachment of GPI anchor to protein GO:0016255 15 6 1,000 5,963E-04 0,01434815 ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 1,000 5,963E-04 0,01420609 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! monocyte differentiation GO:0030224 12 6 1,000 5,963E-04 0,01406681 ! response to UV-C GO:0010225 11 6 1,000 5,963E-04 0,01393024 ! negative regulation of neuroblast proliferation GO:0007406 21 6 1,000 5,963E-04 0,0137963 ! catecholamine transport GO:0051937 9 6 1,000 5,963E-04 0,0136649 ! fat cell differentiation GO:0045444 50 27 2,000 6,665E-04 0,0151286 ! base-excision repair GO:0006284 41 27 2,000 6,665E-04 0,01498721 ! regulation of helicase activity GO:0051095 15 7 1,000 8,314E-04 0,01852138 ! cytokinesis during cell cycle GO:0033205 11 7 1,000 8,314E-04 0,01835146 ! regulation of gluconeogenesis GO:0006111 7 7 1,000 8,314E-04 0,01818463 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 1,000 8,314E-04 0,0180208 ! lipoprotein transport GO:0042953 14 7 1,000 8,314E-04 0,0178599 ! synaptic transmission, dopaminergic GO:0001963 12 7 1,000 8,314E-04 0,01770185 ! response to dietary excess GO:0002021 8 7 1,000 8,314E-04 0,01754657 ! negative regulation of DNA recombination GO:0045910 15 7 1,000 8,314E-04 0,01739399 ! positive regulation of mitotic cell cycle GO:0045931 12 7 1,000 8,314E-04 0,01724404 ! centrosome duplication GO:0051298 13 7 1,000 8,314E-04 0,01709666 ! eating behavior GO:0042755 7 7 1,000 8,314E-04 0,01695177 ! B cell lineage commitment GO:0002326 21 7 1,000 8,314E-04 0,01680932 ! T cell lineage commitment GO:0002360 16 7 1,000 8,314E-04 0,01666924 ! regulation of lipid transport GO:0032368 14 7 1,000 8,314E-04 0,01653148 ! response to tumor cell GO:0002347 13 7 1,000 8,314E-04 0,01639597 ! protein modification by small protein removal GO:0070646 16 7 1,000 8,314E-04 0,01626267 ! adult feeding behavior GO:0008343 9 7 1,000 8,314E-04 0,01613152 ! developmental maturation GO:0021700 116 66 3,000 8,474E-04 0,01631137 ! hexose catabolic process GO:0019320 104 67 3,000 8,968E-04 0,0171244 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 1,104E-03 0,02091251 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 1,000 1,104E-03 0,02074913 GO:0016446|somatic hypermutation of immunoglobulin genes, ! meiotic prophase I GO:0007128 13 8 1,000 1,104E-03 0,02058829 ! neurotransmitter uptake GO:0001504 14 8 1,000 1,104E-03 0,02042991 ! membrane hyperpolarization GO:0060081 10 8 1,000 1,104E-03 0,02027396 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 1,000 1,104E-03 0,02012037 ! regulation of response to extracellular stimulus GO:0032104 13 8 1,000 1,104E-03 0,01996909 GO:0032107|regulation of response to nutrient levels, ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 1,104E-03 0,01982007 ! DNA topological change GO:0006265 12 8 1,000 1,104E-03 0,01967325 ! regulation of fat cell differentiation GO:0045598 15 8 1,000 1,104E-03 0,01952859 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 1,000 1,104E-03 0,01938605 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 1,000 1,104E-03 0,01924557 ! establishment of chromosome localization GO:0051303 12 8 1,000 1,104E-03 0,01910711 GO:0050000|chromosome localization, ! response to ionizing radiation GO:0010212 65 32 2,000 1,104E-03 0,01897428 ! reproductive structure development GO:0048608 113 71 3,000 1,115E-03 0,01901856 ! DNA damage checkpoint GO:0000077 71 33 2,000 1,209E-03 0,0204817 ! negative regulation of protein transport GO:0051224 69 33 2,000 1,209E-03 0,02033848 ! regulation of actin cytoskeleton organization GO:0032956 149 74 3,000 1,3E-03 0,02172832 ! phosphoinositide-mediated signaling GO:0048015 131 75 3,000 1,367E-03 0,02268183 ! middle ear morphogenesis GO:0042474 14 9 1,000 1,413E-03 0,02329038 ! receptor clustering GO:0043113 18 9 1,000 1,413E-03 0,02313194 ! motor axon guidance GO:0008045 16 9 1,000 1,413E-03 0,02297564 ! postreplication repair GO:0006301 22 9 1,000 1,413E-03 0,02282144 ! positive regulation of erythrocyte differentiation GO:0045648 29 9 1,000 1,413E-03 0,0226693 ! regulation of telomere maintenance GO:0032204 14 9 1,000 1,413E-03 0,02251917 ! monosaccharide catabolic process GO:0046365 115 76 3,000 1,436E-03 0,02272682 ! regulation of catabolic process GO:0009894 161 76 3,000 1,436E-03 0,02257828 ! regulation of actin filament-based process GO:0032970 152 77 3,000 1,507E-03 0,02354424 ! DNA integrity checkpoint GO:0031570 75 36 2,000 1,56E-03 0,02421338 ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 3,000 1,581E-03 0,02437808 ! protein oligomerization GO:0051259 139 78 3,000 1,581E-03 0,02422281 ! meiosis I GO:0007127 65 37 2,000 1,69E-03 0,02572905 ! glycogen metabolic process GO:0005977 61 37 2,000 1,69E-03 0,02556723 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 1,000 1,759E-03 0,02645424 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 1,000 1,759E-03 0,02628993 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 1,000 1,759E-03 0,02612765 ! multicellular organism growth GO:0035264 18 10 1,000 1,759E-03 0,02596736 ! epithelial cell development GO:0002064 20 10 1,000 1,759E-03 0,02580902 ! DNA ligation GO:0006266 19 10 1,000 1,759E-03 0,0256526 ! prophase GO:0051324 15 10 1,000 1,759E-03 0,02549807 ! apical protein localization GO:0045176 15 10 1,000 1,759E-03 0,02534538 ! negative regulation of BMP signaling pathway GO:0030514 19 10 1,000 1,759E-03 0,02519452 ! positive regulation of viral reproduction GO:0048524 18 10 1,000 1,759E-03 0,02504544 ! oocyte development GO:0048599 17 10 1,000 1,759E-03 0,02489811 ! mitotic cell cycle checkpoint GO:0007093 76 38 2,000 1,826E-03 0,02569046 ! carbohydrate homeostasis GO:0033500 53 38 2,000 1,826E-03 0,02554109 GO:0042593|glucose homeostasis, ! nucleus organization GO:0006997 67 38 2,000 1,826E-03 0,02539346 ! glucan metabolic process GO:0044042 62 38 2,000 1,826E-03 0,02524752 GO:0006073|cellular glucan metabolic process, ! mammary gland development GO:0030879 86 39 2,000 1,969E-03 0,02706849 ! detection of mechanical stimulus GO:0050982 22 11 1,000 2,141E-03 0,02927047 ! regulation of intracellular pH GO:0051453 19 11 1,000 2,141E-03 0,0291051 ! nitric oxide metabolic process GO:0046209 15 11 1,000 2,141E-03 0,02894159 GO:0006809|nitric oxide biosynthetic process, ! oocyte differentiation GO:0009994 18 11 1,000 2,141E-03 0,0287799 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 1,000 2,141E-03 0,02862002 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! mitochondrion organization GO:0007005 148 86 3,000 2,262E-03 0,03006925 ! alcohol catabolic process GO:0046164 130 86 3,000 2,262E-03 0,02990404 ! female gamete generation GO:0007292 61 41 2,000 2,275E-03 0,0299127 ! regulation of protein transport GO:0051223 154 87 3,000 2,359E-03 0,03085207 GO:0070201|regulation of establishment of protein localization, ! regulation of myeloid cell differentiation GO:0045637 98 42 2,000 2,439E-03 0,03171712 ! dopamine receptor signaling pathway GO:0007212 28 12 1,000 2,559E-03 0,03309699 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 1,000 2,559E-03 0,03292 ! asymmetric protein localization GO:0008105 20 12 1,000 2,559E-03 0,03274489 ! monoamine transport GO:0015844 18 12 1,000 2,559E-03 0,03257164 ! immunoglobulin production during immune response GO:0002381 23 12 1,000 2,559E-03 0,03240021 ! mRNA polyadenylation GO:0006378 23 12 1,000 2,559E-03 0,03223058 ! negative regulation of mast cell proliferation GO:0070667 23 12 1,000 2,559E-03 0,03206271 GO:0042130|negative regulation of T cell proliferation, ! regulation of steroid biosynthetic process GO:0050810 17 12 1,000 2,559E-03 0,03189658 ! epithelial cell differentiation GO:0030855 79 43 2,000 2,609E-03 0,03236285 ! regulation of epithelial cell proliferation GO:0050678 111 43 2,000 2,609E-03 0,03219689 ! developmental growth GO:0048589 82 44 2,000 2,787E-03 0,03421657 ! regulation of actin filament polymerization GO:0030833 87 45 2,000 2,973E-03 0,03630491 ! regulation of cellular pH GO:0030641 22 13 1,000 3,011E-03 0,03659027 ! chromatin silencing GO:0006342 26 13 1,000 3,011E-03 0,0364064 ! regulation of fatty acid oxidation GO:0046320 27 13 1,000 3,011E-03 0,03622437 ! mRNA 3'-end processing GO:0031124 24 13 1,000 3,011E-03 0,03604415 ! positive regulation of protein polymerization GO:0032273 25 13 1,000 3,011E-03 0,03586571 ! cytoplasmic sequestering of protein GO:0051220 24 13 1,000 3,011E-03 0,03568903 ! pigmentation GO:0043473 100 46 2,000 3,165E-03 0,0373308 ! response to insulin stimulus GO:0032868 95 46 2,000 3,165E-03 0,0371487 ! positive regulation of protein transport GO:0051222 72 46 2,000 3,165E-03 0,03696836 ! regulation of protein localization GO:0032880 176 97 3,000 3,496E-03 0,04063802 ! regulation of S phase GO:0033261 23 14 1,000 3,498E-03 0,04046634 ! non-recombinational repair GO:0000726 25 14 1,000 3,498E-03 0,04027272 GO:0006303|double-strand break repair via nonhomologous end joining, ! RNA polyadenylation GO:0043631 30 14 1,000 3,498E-03 0,04008095 ! regulation of mRNA processing GO:0050684 24 14 1,000 3,498E-03 0,03989099 ! actin cytoskeleton reorganization GO:0031532 33 14 1,000 3,498E-03 0,03970283 ! regulation of erythrocyte differentiation GO:0045646 44 14 1,000 3,498E-03 0,03951643 ! positive regulation of cell cycle GO:0045787 89 48 2,000 3,573E-03 0,04017098 ! activation of caspase activity GO:0006919 84 48 2,000 3,573E-03 0,03998413 ! DNA-dependent DNA replication GO:0006261 74 49 2,000 3,788E-03 0,04219772 ! cell cycle arrest GO:0007050 213 100 3,000 3,899E-03 0,0432292 ! embryonic hindlimb morphogenesis GO:0035116 33 15 1,000 4,02E-03 0,04436386 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 1,000 4,02E-03 0,04416128 ! histone deacetylation GO:0016575 20 15 1,000 4,02E-03 0,04396055 ! synaptic transmission, cholinergic GO:0007271 24 15 1,000 4,02E-03 0,04376163 ! muscle maintenance GO:0046716 26 15 1,000 4,02E-03 0,04356451 ! dopamine metabolic process GO:0042417 35 15 1,000 4,02E-03 0,04336915 ! covalent chromatin modification GO:0016569 101 52 2,000 4,481E-03 0,04813288 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 4,575E-03 0,04891891 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 1,000 4,575E-03 0,04870245 ! regulation of neurotransmitter secretion GO:0046928 33 16 1,000 4,575E-03 0,0484879 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 1,000 4,575E-03 0,04827524 ! positive regulation of protein import into nucleus GO:0042307 30 16 1,000 4,575E-03 0,04806443 ! negative regulation of leukocyte proliferation GO:0070664 31 16 1,000 4,575E-03 0,04785545 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 4,575E-03 0,04764829 ! regulation of protein polymerization GO:0032271 103 53 2,000 4,728E-03 0,04903302 ! positive regulation of protein complex assembly GO:0031334 32 17 1,000 5,163E-03 0,05331427 ! signal complex assembly GO:0007172 41 17 1,000 5,163E-03 0,05308643 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 1,000 5,163E-03 0,05286053 ! regulation of viral genome replication GO:0045069 28 17 1,000 5,163E-03 0,05263655 ! regulation of survival gene product expression GO:0045884 33 17 1,000 5,163E-03 0,05241445 ! negative regulation of protein catabolic process GO:0042177 40 17 1,000 5,163E-03 0,05219422 ! DNA unwinding during replication GO:0006268 27 17 1,000 5,163E-03 0,05197584 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 1,000 5,163E-03 0,05175927 ! RNA 3'-end processing GO:0031123 34 17 1,000 5,163E-03 0,0515445 ! positive regulation of caspase activity GO:0043280 95 55 2,000 5,246E-03 0,05215642 GO:0010952|positive regulation of peptidase activity, ! cellular polysaccharide metabolic process GO:0044264 86 55 2,000 5,246E-03 0,05194179 ! aging GO:0007568 103 55 2,000 5,246E-03 0,05172891 ! positive regulation of anti-apoptosis GO:0045768 39 18 1,000 5,784E-03 0,05680273 ! regulation of lipid biosynthetic process GO:0046890 25 18 1,000 5,784E-03 0,05657183 ! centrosome cycle GO:0007098 25 18 1,000 5,784E-03 0,05634279 ! epidermis morphogenesis GO:0048730 40 18 1,000 5,784E-03 0,0561156 ! peptidyl-serine phosphorylation GO:0018105 38 18 1,000 5,784E-03 0,05589024 ! regulation of steroid metabolic process GO:0019218 30 18 1,000 5,784E-03 0,05566668 ! long-chain fatty acid transport GO:0015909 31 18 1,000 5,784E-03 0,0554449 ! regulation of BMP signaling pathway GO:0030510 32 18 1,000 5,784E-03 0,05522488 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 1,000 5,784E-03 0,0550066 ! adult behavior GO:0030534 99 58 2,000 6,085E-03 0,05763658 ! bile acid metabolic process GO:0008206 29 19 1,000 6,438E-03 0,06074131 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 1,000 6,438E-03 0,06050404 ! cellular response to unfolded protein GO:0034620 33 19 1,000 6,438E-03 0,06026861 GO:0030968|endoplasmic reticulum unfolded protein response, ! neuromuscular junction development GO:0007528 34 19 1,000 6,438E-03 0,06003502 ! cellular pigmentation GO:0033059 36 19 1,000 6,438E-03 0,05980322 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 1,000 6,438E-03 0,05957321 ! protein amino acid autophosphorylation GO:0046777 141 60 2,000 6,686E-03 0,06163136 ! regulation of protein complex assembly GO:0043254 117 61 2,000 6,999E-03 0,06427302 ! response to peptide hormone stimulus GO:0043434 122 61 2,000 6,999E-03 0,06402864 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 1,000 7,123E-03 0,06491771 ! protein amino acid deacetylation GO:0006476 29 20 1,000 7,123E-03 0,06467273 ! transcription from RNA polymerase III promoter GO:0006383 41 20 1,000 7,123E-03 0,0644296 ! regulation of carbohydrate metabolic process GO:0006109 38 20 1,000 7,123E-03 0,06418829 GO:0010675|regulation of cellular carbohydrate metabolic process, ! response to alkaloid GO:0043279 38 20 1,000 7,123E-03 0,06394879 ! DNA duplex unwinding GO:0032508 31 20 1,000 7,123E-03 0,06371106 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 1,000 7,123E-03 0,06347509 ! regulation of fatty acid metabolic process GO:0019217 38 20 1,000 7,123E-03 0,06324087 ! peptidyl-serine modification GO:0018209 43 20 1,000 7,123E-03 0,06300836 ! negative regulation of T cell activation GO:0050868 40 20 1,000 7,123E-03 0,06277756 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 1,000 7,123E-03 0,06254845 ! regulation of homeostatic process GO:0032844 134 62 2,000 7,321E-03 0,06405065 ! regulation of lipid metabolic process GO:0019216 115 63 2,000 7,651E-03 0,06669967 ! hindlimb morphogenesis GO:0035137 43 21 1,000 7,84E-03 0,06809877 ! regulation of neurotransmitter transport GO:0051588 42 21 1,000 7,84E-03 0,06785381 ! cell structure disassembly during apoptosis GO:0006921 30 21 1,000 7,84E-03 0,0676106 ! cholesterol biosynthetic process GO:0006695 37 21 1,000 7,84E-03 0,06736914 ! negative regulation of intracellular transport GO:0032387 41 21 1,000 7,84E-03 0,06712939 ! positive regulation of protein catabolic process GO:0045732 38 22 1,000 8,588E-03 0,07327397 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 1,000 8,588E-03 0,07301505 ! central nervous system neuron development GO:0021954 46 22 1,000 8,588E-03 0,07275796 ! positive regulation of cytoskeleton organization GO:0051495 48 22 1,000 8,588E-03 0,07250267 ! activation of JUN kinase activity GO:0007257 42 22 1,000 8,588E-03 0,07224916 ! somatic diversification of immunoglobulins GO:0016445 50 22 1,000 8,588E-03 0,07199742 ! protein stabilization GO:0050821 39 22 1,000 8,588E-03 0,07174743 ! fatty acid biosynthetic process GO:0006633 124 66 2,000 8,695E-03 0,07238949 ! chromosome segregation GO:0007059 113 67 2,000 9,061E-03 0,07517267 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 9,367E-03 0,07744663 ! myeloid leukocyte differentiation GO:0002573 40 23 1,000 9,367E-03 0,0771814 ! regulation of anti-apoptosis GO:0045767 53 23 1,000 9,367E-03 0,07691798 ! regulation of DNA recombination GO:0000018 48 23 1,000 9,367E-03 0,07665635 ! activation of pro-apoptotic gene products GO:0008633 47 23 1,000 9,367E-03 0,0763965 ! barbed-end actin filament capping GO:0051016 50 23 1,000 9,367E-03 0,07613841 GO:0051693|actin filament capping, ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 1,000 9,367E-03 0,07588205 ! regulation of viral reproduction GO:0050792 38 23 1,000 9,367E-03 0,07562741 ! fatty acid transport GO:0015908 44 23 1,000 9,367E-03 0,07537447 ! nerve-nerve synaptic transmission GO:0007270 49 23 1,000 9,367E-03 0,07512323 ! negative regulation of catabolic process GO:0009895 50 23 1,000 9,367E-03 0,07487365 ! cell cycle checkpoint GO:0000075 137 69 2,000 9,818E-03 0,07822277 ! urogenital system development GO:0001655 137 69 2,000 9,818E-03 0,07796461 ! protein import into nucleus, translocation GO:0000060 46 24 1,000 0,01017601 0,08053775 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 1,000 0,01017601 0,08027369 GO:0016444|somatic cell DNA recombination, ! DNA catabolic process, endonucleolytic GO:0000737 35 24 1,000 0,01017601 0,08001136 ! central nervous system neuron differentiation GO:0021953 50 24 1,000 0,01017601 0,07975074 ! membrane depolarization GO:0051899 39 24 1,000 0,01017601 0,07949181 ! protein tetramerization GO:0051262 52 24 1,000 0,01017601 0,07923455 ! B cell activation GO:0042113 160 71 2,000 0,0106121 0,08236356 ! myelination GO:0042552 45 25 1,000 0,01101488 0,08521476 ! chromosome condensation GO:0030261 45 25 1,000 0,01101488 0,08494164 ! response to starvation GO:0042594 42 25 1,000 0,01101488 0,08467026 ! osteoblast differentiation GO:0001649 60 25 1,000 0,01101488 0,08440061 ! negative regulation of cell development GO:0010721 73 25 1,000 0,01101488 0,08413267 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 1,000 0,01101488 0,08386643 ! hydrogen peroxide metabolic process GO:0042743 33 25 1,000 0,01101488 0,08360187 ! immunoglobulin production GO:0002377 55 25 1,000 0,01101488 0,08333897 GO:0002440|production of molecular mediator of immune response, ! cellular response to nutrient levels GO:0031669 41 25 1,000 0,01101488 0,08307772 ! regulation of caspase activity GO:0043281 122 72 2,000 0,01102244 0,08287494 ! regulation of blood pressure GO:0008217 125 73 2,000 0,01144184 0,08576036 ! regulation of endopeptidase activity GO:0052548 125 74 2,000 0,01187035 0,08869587 ! eye development GO:0001654 143 74 2,000 0,01187035 0,08842127 ! negative regulation of actin filament depolymerization GO:0030835 55 26 1,000 0,01188318 0,08824361 ! negative regulation of actin filament polymerization GO:0030837 53 26 1,000 0,01188318 0,08797209 ! regulation of transcription factor import into nucleus GO:0042990 54 26 1,000 0,01188318 0,08770224 ! microtubule organizing center organization GO:0031023 39 26 1,000 0,01188318 0,08743403 GO:0051297|centrosome organization, ! somatic diversification of immune receptors GO:0002200 56 26 1,000 0,01188318 0,08716747 ! positive regulation of JUN kinase activity GO:0043507 51 26 1,000 0,01188318 0,08690252 ! regulation of fibroblast proliferation GO:0048145 52 27 1,000 0,01278051 0,09318155 ! mitochondrial membrane organization GO:0007006 57 27 1,000 0,01278051 0,09290004 ! response to toxin GO:0009636 47 27 1,000 0,01278051 0,09262022 ! regulation of chromosome organization GO:0033044 42 27 1,000 0,01278051 0,09234208 ! negative regulation of protein polymerization GO:0032272 55 27 1,000 0,01278051 0,09206561 ! negative regulation of lymphocyte activation GO:0051250 53 27 1,000 0,01278051 0,09179078 ! regulation of actin filament depolymerization GO:0030834 58 28 1,000 0,01370647 0,09814815 ! regulation of JUN kinase activity GO:0043506 58 28 1,000 0,01370647 0,09785691 ! regulation of peptidase activity GO:0052547 134 79 2,000 0,01415044 0,10072771 ! negative regulation of protein complex assembly GO:0031333 59 29 1,000 0,01466067 0,10405182 ! regulation of pH GO:0006885 43 29 1,000 0,01466067 0,10374578 ! cellular iron ion homeostasis GO:0006879 51 29 1,000 0,01466067 0,10344154 ! catechol metabolic process GO:0009712 54 29 1,000 0,01466067 0,10313908 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! regulation of peptide secretion GO:0002791 47 29 1,000 0,01466067 0,10283839 ! response to organic cyclic substance GO:0014070 55 29 1,000 0,01466067 0,10253944 ! cell fate determination GO:0001709 60 29 1,000 0,01466067 0,10224222 ! sterol biosynthetic process GO:0016126 52 29 1,000 0,01466067 0,10194672 ! cellular response to extracellular stimulus GO:0031668 48 29 1,000 0,01466067 0,10165293 ! tissue homeostasis GO:0001894 48 29 1,000 0,01466067 0,10136082 GO:0048871|multicellular organismal homeostasis, ! cholesterol metabolic process GO:0008203 136 82 2,000 0,01562942 0,10774896 ! response to nutrient GO:0007584 125 82 2,000 0,01562942 0,10744111 ! phenol metabolic process GO:0018958 55 30 1,000 0,0156427 0,10722602 ! ensheathment of neurons GO:0007272 57 30 1,000 0,0156427 0,1069214 GO:0008366|axon ensheathment, ! negative regulation of leukocyte activation GO:0002695 56 30 1,000 0,0156427 0,10661851 ! GPI anchor biosynthetic process GO:0006506 53 31 1,000 0,01665218 0,11317836 ! iron ion homeostasis GO:0055072 54 31 1,000 0,01665218 0,11285954 ! negative regulation of transcription regulator activity GO:0090048 58 31 1,000 0,01665218 0,11254252 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of transport GO:0051051 153 84 2,000 0,01666196 0,11229323 ! response to hydrogen peroxide GO:0042542 50 32 1,000 0,01768872 0,11888004 ! negative regulation of response to external stimulus GO:0032102 47 32 1,000 0,01768872 0,1185489 ! GPI anchor metabolic process GO:0006505 56 32 1,000 0,01768872 0,11821959 ! spindle organization GO:0007051 46 32 1,000 0,01768872 0,11789212 ! response to mechanical stimulus GO:0009612 57 32 1,000 0,01768872 0,11756645 ! regulation of protein import into nucleus GO:0042306 63 32 1,000 0,01768872 0,11724257 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 1,000 0,01768872 0,11692048 ! peripheral nervous system development GO:0007422 64 32 1,000 0,01768872 0,11660015 ! hindbrain development GO:0030902 61 32 1,000 0,01768872 0,11628157 ! positive regulation of catabolic process GO:0009896 64 32 1,000 0,01768872 0,11596472 ! gene silencing GO:0016458 65 32 1,000 0,01768872 0,1156496 ! positive regulation of gene-specific transcription GO:0043193 65 33 1,000 0,01875194 0,12226873 ! adult locomotory behavior GO:0008344 59 33 1,000 0,01875194 0,12193827 ! glial cell differentiation GO:0010001 63 34 1,000 0,01984146 0,12867533 ! xenobiotic metabolic process GO:0006805 51 34 1,000 0,01984146 0,12832943 ! mismatch repair GO:0006298 46 34 1,000 0,01984146 0,12798538 ! placenta development GO:0001890 53 34 1,000 0,01984146 0,12764317 ! sex differentiation GO:0007548 145 90 2,000 0,01998428 0,12821914 ! sterol metabolic process GO:0016125 152 91 2,000 0,02057087 0,13163166 ! female gonad development GO:0008585 58 35 1,000 0,0209569 0,13374618 ! negative regulation of hydrolase activity GO:0051346 62 35 1,000 0,0209569 0,13339236 ! positive regulation of MAP kinase activity GO:0043406 160 93 2,000 0,02177226 0,13821652 ! regulation of membrane potential GO:0042391 164 93 2,000 0,02177226 0,13785279 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 1,000 0,02209791 0,1395474 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! maintenance of protein location in cell GO:0032507 86 36 1,000 0,02209791 0,1391821 ! regulation of proteolysis GO:0030162 72 36 1,000 0,02209791 0,1388187 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 1,000 0,02209791 0,13845719 ! negative regulation of cell activation GO:0050866 65 36 1,000 0,02209791 0,13809756 ! forebrain development GO:0030900 188 95 2,000 0,0230113 0,14343312 ! monovalent inorganic cation homeostasis GO:0055067 58 37 1,000 0,02326409 0,14463413 ! negative regulation of DNA binding GO:0043392 68 37 1,000 0,02326409 0,14426137 ! cellular response to insulin stimulus GO:0032869 82 37 1,000 0,02326409 0,14389051 ! leukocyte differentiation GO:0002521 202 96 2,000 0,02364493 0,14587105 ! hormone metabolic process GO:0042445 157 97 2,000 0,02428798 0,14945491 ! positive regulation of DNA metabolic process GO:0051054 72 38 1,000 0,02445511 0,15009945 ! phosphoinositide biosynthetic process GO:0046489 67 38 1,000 0,02445511 0,14971752 ! development of primary female sexual characteristics GO:0046545 67 38 1,000 0,02445511 0,14933752 GO:0046660|female sex differentiation, ! lipid homeostasis GO:0055088 67 38 1,000 0,02445511 0,14895945 ! mRNA catabolic process GO:0006402 71 39 1,000 0,02567058 0,15596822 ! ear morphogenesis GO:0042471 60 39 1,000 0,02567058 0,15557536 ! regulation of action potential in neuron GO:0019228 73 39 1,000 0,02567058 0,15518446 ! response to xenobiotic stimulus GO:0009410 57 39 1,000 0,02567058 0,15479553 ! regulation of hormone secretion GO:0046883 62 40 1,000 0,02691016 0,16186462 ! feeding behavior GO:0007631 59 40 1,000 0,02691016 0,16146097 ! negative regulation of binding GO:0051100 72 40 1,000 0,02691016 0,16105932 ! maintenance of protein location GO:0045185 91 40 1,000 0,02691016 0,16065967 ! cytokinesis GO:0000910 72 40 1,000 0,02691016 0,160262 ! gliogenesis GO:0042063 88 41 1,000 0,0281735 0,16737143 ! regulation of T cell proliferation GO:0042129 71 41 1,000 0,0281735 0,16695919 ! T cell differentiation GO:0030217 81 41 1,000 0,0281735 0,16654897 ! keratinocyte differentiation GO:0030216 62 41 1,000 0,0281735 0,16614076 ! regulation of T cell differentiation GO:0045580 70 41 1,000 0,0281735 0,16573455 ! response to reactive oxygen species GO:0000302 67 42 1,000 0,02946023 0,17288126 ! negative regulation of protein complex disassembly GO:0043242 101 42 1,000 0,02946023 0,17246063 ! monocarboxylic acid transport GO:0015718 85 42 1,000 0,02946023 0,17204203 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 1,000 0,03077002 0,17925588 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,03147391 0,18291358 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,03147391 0,18247282 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,03147391 0,18203419 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,03147391 0,18159765 ! neuron fate determination GO:0048664 7 5 0,000 0,03147391 0,18116321 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,03147391 0,18073084 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,03147391 0,18030053 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,03147391 0,17987226 ! polyol transport GO:0015791 12 5 0,000 0,03147391 0,17944602 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,03147391 0,1790218 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,03147391 0,17859958 ! response to superoxide GO:0000303 10 5 0,000 0,03147391 0,17817934 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,03147391 0,17776108 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,03147391 0,17734478 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,03147391 0,17693042 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,03147391 0,176518 ! female meiosis GO:0007143 7 5 0,000 0,03147391 0,17610749 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,03147391 0,17569889 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,03147391 0,17529218 ! cobalt ion transport GO:0006824 11 5 0,000 0,03147391 0,17488735 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,03147391 0,17448438 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,03147391 0,17408327 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,03147391 0,17368399 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,03147391 0,17328655 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,03147391 0,17289092 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,03147391 0,17249709 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,03147391 0,17210505 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,03147391 0,17171479 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,03147391 0,17132629 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,03147391 0,17093955 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,03147391 0,17055455 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,03147391 0,17017128 ! negative chemotaxis GO:0050919 14 5 0,000 0,03147391 0,16978973 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,03147391 0,16940989 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,03147391 0,16903174 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,03147391 0,16865528 ! behavioral response to pain GO:0048266 9 5 0,000 0,03147391 0,16828049 ! clathrin coat assembly GO:0048268 14 5 0,000 0,03147391 0,16790736 ! Notch receptor processing GO:0007220 8 5 0,000 0,03147391 0,16753589 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,03147391 0,16716605 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,03147391 0,16679784 ! micturition GO:0060073 9 5 0,000 0,03147391 0,16643126 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,03147391 0,16606627 ! copulation GO:0007620 9 5 0,000 0,03147391 0,16570289 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,03147391 0,16534109 ! spermidine metabolic process GO:0008216 7 5 0,000 0,03147391 0,16498087 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,03147391 0,16462222 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,03147391 0,16426512 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,03147391 0,16390957 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,03147391 0,16355555 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,03147391 0,16320306 ! grooming behavior GO:0007625 6 5 0,000 0,03147391 0,16285209 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,03147391 0,16250262 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,03147391 0,16215465 ! response to protozoan GO:0001562 10 5 0,000 0,03147391 0,16180816 ! positive regulation of glycolysis GO:0045821 14 5 0,000 0,03147391 0,16146316 ! lymph vessel development GO:0001945 10 5 0,000 0,03147391 0,16111962 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,03147391 0,16077754 ! endochondral ossification GO:0001958 16 5 0,000 0,03147391 0,16043691 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,03147391 0,16009772 ! parathyroid gland development GO:0060017 13 5 0,000 0,03147391 0,15975996 ! anagen GO:0042640 6 5 0,000 0,03147391 0,15942362 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,03147391 0,1590887 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,03147391 0,15875518 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,03147391 0,15842306 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,03147391 0,15809232 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,03147391 0,15776296 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,03147391 0,15743497 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,03147391 0,15710834 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,03147391 0,15678307 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,03147391 0,15645913 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,03147391 0,15613654 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,03147391 0,15581527 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,03147391 0,15549532 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,03147391 0,15517668 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,03147391 0,15485935 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,03147391 0,15454331 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,03147391 0,15422856 ! histidine catabolic process GO:0006548 6 5 0,000 0,03147391 0,15391508 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,03147391 0,15360288 ! microvillus organization GO:0032528 7 5 0,000 0,03147391 0,15329195 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 0,03147391 0,15298227 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,03147391 0,15267383 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,03147391 0,15236664 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,03147391 0,15206069 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,03147391 0,15175595 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,03147391 0,15145244 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,03147391 0,15115014 ! polyol catabolic process GO:0046174 7 5 0,000 0,03147391 0,15084905 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,03147391 0,15054915 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,03147391 0,15025044 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,03147391 0,14995291 ! muscle cell migration GO:0014812 8 5 0,000 0,03147391 0,14965656 ! mitochondrial fission GO:0000266 8 5 0,000 0,03147391 0,14936138 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,03147391 0,14906736 ! mRNA transcription GO:0009299 9 5 0,000 0,03147391 0,1487745 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,03147391 0,14848279 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,03147391 0,14819221 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,03147391 0,14790278 GO:0051489|regulation of filopodium assembly, ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,03147391 0,14761447 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,03147391 0,14732728 GO:0060177|regulation of angiotensin metabolic process, ! response to food GO:0032094 6 5 0,000 0,03147391 0,14704121 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,03147391 0,14675624 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,03147391 0,14647238 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,03147391 0,14618962 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,03147391 0,14590794 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,03147391 0,14562735 ! regulation of phospholipase A2 activity GO:0032429 13 5 0,000 0,03147391 0,14534783 ! forebrain neuron development GO:0021884 13 5 0,000 0,03147391 0,14506939 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,03147391 0,14479201 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,03147391 0,14451569 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,03147391 0,14424042 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,03147391 0,1439662 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,03147391 0,14369302 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,03147391 0,14342087 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,03147391 0,14314976 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,03147391 0,14287966 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,03147391 0,14261059 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,03147391 0,14234252 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,03147391 0,14207546 ! basic amino acid transport GO:0015802 11 5 0,000 0,03147391 0,1418094 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,03147391 0,14154434 ! depyrimidination GO:0045008 10 5 0,000 0,03147391 0,14128026 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,03147391 0,14101717 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,03147391 0,14075506 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,03147391 0,14049392 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,03147391 0,14023374 GO:0006882|cellular zinc ion homeostasis, ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,03147391 0,13997453 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,03147391 0,13971628 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,03147391 0,13945897 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,03147391 0,13920261 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,03147391 0,13894719 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,03147391 0,13869271 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,03147391 0,13843916 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,03147391 0,13818654 ! response to arsenic GO:0046685 10 5 0,000 0,03147391 0,13793483 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,03147391 0,13768404 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,03147391 0,13743416 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,03147391 0,13718518 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,03147391 0,13693711 ! response to cadmium ion GO:0046686 7 5 0,000 0,03147391 0,13668993 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,03147391 0,13644364 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,03147391 0,13619824 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,03147391 0,13595372 ! decidualization GO:0046697 11 5 0,000 0,03147391 0,13571007 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,03147391 0,1354673 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,03147391 0,1352254 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,03147391 0,13498435 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,03147391 0,13474417 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,03147391 0,13450483 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,03147391 0,13426635 ! neural tube patterning GO:0021532 7 5 0,000 0,03147391 0,13402871 ! embryonic cleavage GO:0040016 6 5 0,000 0,03147391 0,13379191 ! peroxisome fission GO:0016559 5 5 0,000 0,03147391 0,13355595 ! histone demethylation GO:0016577 10 5 0,000 0,03147391 0,13332081 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,03147391 0,1330865 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,03147391 0,13285302 ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,03147391 0,13262035 ! enteric nervous system development GO:0048484 8 5 0,000 0,03147391 0,1323885 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,03147391 0,13215745 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,03147391 0,13192721 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,03147391 0,13169778 ! muscle cell proliferation GO:0033002 11 5 0,000 0,03147391 0,13146913 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,03147391 0,13124128 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,03147391 0,13101422 ! plasminogen activation GO:0031639 5 5 0,000 0,03147391 0,13078795 ! B cell homeostasis GO:0001782 13 5 0,000 0,03147391 0,13056245 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,03147391 0,13033773 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,03147391 0,13011378 ! metaphase GO:0051323 8 5 0,000 0,03147391 0,1298906 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,03147391 0,12966819 ! cellular response to nutrient GO:0031670 8 5 0,000 0,03147391 0,12944653 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,03147391 0,12922563 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,03147391 0,12900549 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,03147391 0,12878609 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,03147391 0,12856744 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,03147391 0,12834953 ! response to redox state GO:0051775 5 5 0,000 0,03147391 0,12813235 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,03147391 0,12791591 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,03147391 0,1277002 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,03147391 0,12748522 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,03147391 0,12727096 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,03147391 0,12705742 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,03147391 0,12684459 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,03147391 0,12663248 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,03147391 0,12642107 ! striatum development GO:0021756 9 5 0,000 0,03147391 0,12621037 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,03147391 0,12600037 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,03147391 0,12579107 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,03147391 0,12558246 ! glial cell migration GO:0008347 11 5 0,000 0,03147391 0,12537454 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,03147391 0,12516731 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,03147391 0,12496076 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,03147391 0,12475489 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,03147391 0,12454971 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,03147391 0,12434519 ! neuroprotection GO:0043526 6 5 0,000 0,03147391 0,12414135 ! neural plate development GO:0001840 8 5 0,000 0,03147391 0,12393817 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,03147391 0,12373566 ! regulation of sensory perception GO:0051931 7 5 0,000 0,03147391 0,1235338 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,03147391 0,12333261 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,03147391 0,12313207 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,03147391 0,12293218 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,03147391 0,12273294 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,03147391 0,12253434 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,03147391 0,12233638 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,03147391 0,12213907 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,03147391 0,12194239 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,03147391 0,12174634 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,03147391 0,12155092 GO:0022011|myelination in the peripheral nervous system, ! drug metabolic process GO:0017144 6 5 0,000 0,03147391 0,12135612 ! stem cell division GO:0017145 11 5 0,000 0,03147391 0,12116195 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,03147391 0,1209684 ! organ regeneration GO:0031100 7 5 0,000 0,03147391 0,12077547 ! carnitine metabolic process GO:0009437 7 5 0,000 0,03147391 0,12058315 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,03147391 0,12039145 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,03147391 0,12020035 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 1,000 0,03210253 0,1224068 ! B cell differentiation GO:0030183 107 44 1,000 0,03210253 0,12221312 ! maintenance of location in cell GO:0051651 97 44 1,000 0,03210253 0,12202005 ! detection of stimulus involved in sensory perception GO:0050906 66 45 1,000 0,03345741 0,1269693 ! branching morphogenesis of a tube GO:0048754 97 45 1,000 0,03345741 0,12676934 ! cell growth GO:0016049 84 45 1,000 0,03345741 0,12657002 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 1,000 0,03483433 0,13157206 ! regulation of gene-specific transcription GO:0032583 96 46 1,000 0,03483433 0,13136583 ! epidermal cell differentiation GO:0009913 68 46 1,000 0,03483433 0,13116025 ! response to calcium ion GO:0051592 81 47 1,000 0,03623295 0,13621326 ! endosome transport GO:0016197 108 47 1,000 0,03623295 0,13600076 ! JNK cascade GO:0007254 91 47 1,000 0,03623295 0,13578892 ! regulation of JNK cascade GO:0046328 94 47 1,000 0,03623295 0,13557774 ! protein homooligomerization GO:0051260 76 47 1,000 0,03623295 0,13536722 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,03764942 0,14044109 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,03764942 0,14022369 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,03764942 0,14000696 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,03764942 0,1397909 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,03764942 0,1395755 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,03764942 0,13936077 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,03764942 0,1391467 ! sleep GO:0030431 13 6 0,000 0,03764942 0,13893329 ! response to oxygen radical GO:0000305 11 6 0,000 0,03764942 0,13872052 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,03764942 0,13850841 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,03764942 0,13829695 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,03764942 0,13808613 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,03764942 0,13787596 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,03764942 0,13766642 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,03764942 0,13745752 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,03764942 0,13724925 ! forebrain regionalization GO:0021871 8 6 0,000 0,03764942 0,13704161 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,03764942 0,1368346 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,03764942 0,13662821 ! response to zinc ion GO:0010043 9 6 0,000 0,03764942 0,13642244 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,03764942 0,1362173 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,03764942 0,13601277 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,03764942 0,13580885 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,03764942 0,13560554 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,03764942 0,13540284 ! malate metabolic process GO:0006108 11 6 0,000 0,03764942 0,13520075 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,03764942 0,13499926 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,03764942 0,13479837 ! protein refolding GO:0042026 15 6 0,000 0,03764942 0,13459807 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,03764942 0,13439837 ! opsonization GO:0008228 8 6 0,000 0,03764942 0,13419926 ! mating behavior GO:0007617 7 6 0,000 0,03764942 0,13400074 ! neuron remodeling GO:0016322 15 6 0,000 0,03764942 0,13380281 ! erythrocyte maturation GO:0043249 7 6 0,000 0,03764942 0,13360546 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,03764942 0,13340869 ! equilibrioception GO:0050957 14 6 0,000 0,03764942 0,1332125 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,03764942 0,13301689 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,03764942 0,13282185 ! photoreceptor cell development GO:0042461 10 6 0,000 0,03764942 0,13262738 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,03764942 0,13243348 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,03764942 0,13224015 ! response to interferon-gamma GO:0034341 15 6 0,000 0,03764942 0,13204738 ! toxin metabolic process GO:0009404 11 6 0,000 0,03764942 0,13185517 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,03764942 0,13166352 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,03764942 0,13147243 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,03764942 0,13128189 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,03764942 0,1310919 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,03764942 0,13090246 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,03764942 0,13071357 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,03764942 0,13052522 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,03764942 0,13033741 ! thymic T cell selection GO:0045061 12 6 0,000 0,03764942 0,13015015 ! protein lipoylation GO:0009249 10 6 0,000 0,03764942 0,12996342 ! cysteine metabolic process GO:0006534 10 6 0,000 0,03764942 0,12977722 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,03764942 0,12959156 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,03764942 0,12940643 ! glutamate catabolic process GO:0006538 10 6 0,000 0,03764942 0,12922183 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,03764942 0,12903775 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,03764942 0,1288542 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,03764942 0,12867117 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,03764942 0,12848866 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,03764942 0,12830666 ! hyperosmotic response GO:0006972 9 6 0,000 0,03764942 0,12812518 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,03764942 0,12794421 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,03764942 0,12776376 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,03764942 0,12758381 ! urea metabolic process GO:0019627 7 6 0,000 0,03764942 0,12740436 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,03764942 0,12722542 ! neutrophil activation GO:0042119 8 6 0,000 0,03764942 0,12704699 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,03764942 0,12686905 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,03764942 0,12669161 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,03764942 0,12651467 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,03764942 0,12633822 ! neuron apoptosis GO:0051402 9 6 0,000 0,03764942 0,12616226 ! nucleoside salvage GO:0043174 9 6 0,000 0,03764942 0,12598679 GO:0006166|purine ribonucleoside salvage, ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,03764942 0,12581181 ! T cell mediated immunity GO:0002456 16 6 0,000 0,03764942 0,12563731 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,03764942 0,1254633 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 0,03764942 0,12528977 ! carnitine transport GO:0015879 10 6 0,000 0,03764942 0,12511672 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,03764942 0,12494414 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,03764942 0,12477204 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,03764942 0,12460042 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,03764942 0,12442926 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,03764942 0,12425858 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,03764942 0,12408836 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,03764942 0,12391861 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,03764942 0,12374932 ! establishment of spindle localization GO:0051293 12 6 0,000 0,03764942 0,12358049 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,03764942 0,12341213 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,03764942 0,12324422 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 14 6 0,000 0,03764942 0,12307677 ! astrocyte development GO:0014002 15 6 0,000 0,03764942 0,12290977 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,03764942 0,12274323 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,03764942 0,12257713 ! interaction with symbiont GO:0051702 13 6 0,000 0,03764942 0,12241149 ! regulation of dendrite development GO:0050773 16 6 0,000 0,03764942 0,12224629 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,03764942 0,12208154 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,03764942 0,12191723 ! response to copper ion GO:0046688 10 6 0,000 0,03764942 0,12175336 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,03764942 0,12158994 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,03764942 0,12142695 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,03764942 0,12126439 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,03764942 0,12110228 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,03764942 0,12094059 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,03764942 0,12077934 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,03764942 0,12061851 ! hair follicle maturation GO:0048820 7 6 0,000 0,03764942 0,12045811 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,03764942 0,12029814 ! Schwann cell development GO:0014044 15 6 0,000 0,03764942 0,1201386 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,03764942 0,11997947 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,03764942 0,11982077 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,03764942 0,11966249 ! subpallium development GO:0021544 10 6 0,000 0,03764942 0,11950462 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,03764942 0,11934717 ! histone ubiquitination GO:0016574 8 6 0,000 0,03764942 0,11919013 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,03764942 0,11903351 ! maintenance of organ identity GO:0048496 9 6 0,000 0,03764942 0,1188773 ! G2 phase GO:0051319 16 6 0,000 0,03764942 0,1187215 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,03764942 0,1185661 ! establishment of planar polarity GO:0001736 7 6 0,000 0,03764942 0,11841111 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,03764942 0,11825653 ! membrane to membrane docking GO:0022614 14 6 0,000 0,03764942 0,11810235 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,03764942 0,11794857 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,03764942 0,11779519 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,03764942 0,11764221 ! receptor internalization GO:0031623 10 6 0,000 0,03764942 0,11748963 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,03764942 0,11733744 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,03764942 0,11718564 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,03764942 0,11703424 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,03764942 0,11688323 ! protein deubiquitination GO:0016579 14 6 0,000 0,03764942 0,11673261 ! protein destabilization GO:0031648 9 6 0,000 0,03764942 0,11658237 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,03764942 0,11643252 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,03764942 0,11628306 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,03764942 0,11613398 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,03764942 0,11598528 ! progesterone metabolic process GO:0042448 10 6 0,000 0,03764942 0,11583696 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,03764942 0,11568902 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,03764942 0,11554146 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,03764942 0,11539427 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,03764942 0,11524746 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,03764942 0,11510102 ! determination of adult lifespan GO:0008340 15 6 0,000 0,03764942 0,11495495 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,03764942 0,11480926 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,03764942 0,11466393 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,03764942 0,11451897 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,03764942 0,11437437 ! sensory cilium assembly GO:0035058 10 6 0,000 0,03764942 0,11423014 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,03764942 0,11408628 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,03764942 0,11394277 ! maternal placenta development GO:0001893 12 6 0,000 0,03764942 0,11379963 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,03764942 0,11365684 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,03764942 0,11351441 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,03764942 0,11337234 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,03764942 0,11323063 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,03764942 0,11308927 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,03764942 0,11294826 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,03764942 0,1128076 ! mitochondrial transport GO:0006839 82 48 1,000 0,03765295 0,11267787 ! cellular component disassembly GO:0022411 86 48 1,000 0,03765295 0,11253789 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 1,000 0,03765295 0,11239827 ! regulation of lymphocyte differentiation GO:0045619 81 48 1,000 0,03765295 0,11225899 ! regulation of mast cell proliferation GO:0070666 81 48 1,000 0,03765295 0,11212006 ! protein amino acid lipidation GO:0006497 95 49 1,000 0,039094 0,1162672 ! regulation of action potential GO:0001508 95 49 1,000 0,039094 0,11612366 ! regulation of protein complex disassembly GO:0043244 113 49 1,000 0,039094 0,11598048 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 1,000 0,039094 0,11583764 ! immunoglobulin mediated immune response GO:0016064 83 49 1,000 0,039094 0,11569516 GO:0019724|B cell mediated immunity, ! detection of abiotic stimulus GO:0009582 74 49 1,000 0,039094 0,11555303 ! histone modification GO:0016570 91 50 1,000 0,04055578 0,11972662 ! regulation of gene expression, epigenetic GO:0040029 105 50 1,000 0,04055578 0,1195799 ! negative regulation of immune system process GO:0002683 95 50 1,000 0,04055578 0,11943353 ! response to estrogen stimulus GO:0043627 93 51 1,000 0,04203796 0,12364709 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 1,000 0,04203796 0,12349612 ! regulation of leukocyte proliferation GO:0070663 88 51 1,000 0,04203796 0,12334551 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of cell shape GO:0008360 125 51 1,000 0,04203796 0,12319528 ! regulation of angiogenesis GO:0045765 114 52 1,000 0,04354023 0,12744256 ! membrane fusion GO:0006944 110 52 1,000 0,04354023 0,12728771 ! morphogenesis of a branching structure GO:0001763 111 52 1,000 0,04354023 0,12713323 ! amino acid activation GO:0043038 92 52 1,000 0,04354023 0,12697913 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! synapse organization GO:0050808 85 52 1,000 0,04354023 0,1268254 ! tRNA transcription GO:0009304 14 7 0,000 0,04378576 0,12738638 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,04378576 0,12723253 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,04378576 0,12707905 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,04378576 0,12692595 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,04378576 0,12677321 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,04378576 0,12662084 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,04378576 0,12646883 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,04378576 0,12631719 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,04378576 0,12616591 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,04378576 0,12601499 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,04378576 0,12586444 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,04378576 0,12571424 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,04378576 0,1255644 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,04378576 0,12541492 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,04378576 0,1252658 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 0,04378576 0,12511702 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,04378576 0,12496861 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,04378576 0,12482054 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,04378576 0,12467282 ! glycolipid transport GO:0046836 10 7 0,000 0,04378576 0,12452545 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,04378576 0,12437844 GO:0051923|sulfation, ! neuron adhesion GO:0007158 12 7 0,000 0,04378576 0,12423176 ! N-terminal protein amino acid acetylation GO:0006474 13 7 0,000 0,04378576 0,12408544 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,04378576 0,12393945 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,04378576 0,12379381 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,04378576 0,12364851 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,04378576 0,12350356 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,04378576 0,12335894 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,04378576 0,12321466 ! mRNA stabilization GO:0048255 18 7 0,000 0,04378576 0,12307072 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,04378576 0,12292711 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,04378576 0,12278384 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,04378576 0,1226409 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,04378576 0,1224983 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,04378576 0,12235602 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,04378576 0,12221408 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,04378576 0,12207246 ! rhythmic behavior GO:0007622 15 7 0,000 0,04378576 0,12193117 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,04378576 0,12179021 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,04378576 0,12164958 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,04378576 0,12150927 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,04378576 0,12136928 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,04378576 0,12122961 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,04378576 0,12109027 ! mechanosensory behavior GO:0007638 14 7 0,000 0,04378576 0,12095125 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,04378576 0,12081254 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,04378576 0,12067415 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,04378576 0,12053608 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,04378576 0,12039833 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,04378576 0,12026088 ! spinal cord patterning GO:0021511 13 7 0,000 0,04378576 0,12012376 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,04378576 0,11998694 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,04378576 0,11985044 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,04378576 0,11971424 ! adrenal gland development GO:0030325 17 7 0,000 0,04378576 0,11957836 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,04378576 0,11944278 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,04378576 0,11930751 ! ovulation GO:0030728 9 7 0,000 0,04378576 0,11917255 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,04378576 0,11903789 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,04378576 0,11890354 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,04378576 0,11876949 ! microtubule nucleation GO:0007020 20 7 0,000 0,04378576 0,11863574 ! proline biosynthetic process GO:0006561 10 7 0,000 0,04378576 0,11850229 ! thyroid hormone generation GO:0006590 13 7 0,000 0,04378576 0,11836914 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,04378576 0,11823629 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,04378576 0,11810374 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,04378576 0,11797148 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,04378576 0,11783952 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,04378576 0,11770786 ! galactose metabolic process GO:0006012 13 7 0,000 0,04378576 0,11757649 ! vesicle fusion GO:0006906 17 7 0,000 0,04378576 0,11744541 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,04378576 0,11731463 ! intracellular pH reduction GO:0051452 11 7 0,000 0,04378576 0,11718413 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,04378576 0,11705393 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,04378576 0,11692401 ! organ growth GO:0035265 15 7 0,000 0,04378576 0,11679438 ! purine salvage GO:0043101 10 7 0,000 0,04378576 0,11666504 ! nucleoside transport GO:0015858 8 7 0,000 0,04378576 0,11653599 ! parturition GO:0007567 14 7 0,000 0,04378576 0,11640722 ! rRNA modification GO:0000154 14 7 0,000 0,04378576 0,11627874 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,04378576 0,11615053 ! spindle checkpoint GO:0031577 15 7 0,000 0,04378576 0,11602262 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,04378576 0,11589498 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,04378576 0,11576762 ! macrophage differentiation GO:0030225 11 7 0,000 0,04378576 0,11564054 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,04378576 0,11551374 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,04378576 0,11538722 GO:0046676|negative regulation of insulin secretion, ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,04378576 0,11526098 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,04378576 0,11513501 ! fibrinolysis GO:0042730 10 7 0,000 0,04378576 0,11500932 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,04378576 0,1148839 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,04378576 0,11475875 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,04378576 0,11463388 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,04378576 0,11450928 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,04378576 0,11438495 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,04378576 0,11426088 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,04378576 0,11413709 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,04378576 0,11401357 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,04378576 0,11389031 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,04378576 0,11376732 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,04378576 0,11364459 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,04378576 0,11352213 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,04378576 0,11339993 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,04378576 0,11327799 ! regulation of meiosis GO:0040020 12 7 0,000 0,04378576 0,11315632 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,04378576 0,11303491 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,04378576 0,11291376 GO:0002714|positive regulation of B cell mediated immunity, ! oxygen homeostasis GO:0032364 12 7 0,000 0,04378576 0,11279286 ! transcription termination GO:0006353 13 7 0,000 0,04378576 0,11267223 ! regulation of respiratory burst GO:0060263 11 7 0,000 0,04378576 0,11255185 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,04378576 0,11243173 ! anaphase GO:0051322 17 7 0,000 0,04378576 0,11231187 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,04378576 0,11219226 ! axonal fasciculation GO:0007413 18 7 0,000 0,04378576 0,11207291 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,04378576 0,11195381 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,04378576 0,11183496 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,04378576 0,11171637 ! diuresis GO:0030146 12 7 0,000 0,04378576 0,11159802 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,04378576 0,11147993 ! thiamin metabolic process GO:0006772 7 7 0,000 0,04378576 0,11136209 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,04378576 0,11124449 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,04378576 0,11112715 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,04378576 0,11101005 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,04378576 0,11089319 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,04378576 0,11077659 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,04378576 0,11066023 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,04378576 0,11054411 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,04378576 0,11042823 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,04378576 0,1103126 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,04378576 0,11019721 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,04378576 0,11008206 ! lymph node development GO:0048535 10 7 0,000 0,04378576 0,10996716 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,04378576 0,10985249 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,04378576 0,10973806 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,04378576 0,10962387 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,04378576 0,10950991 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,04378576 0,10939619 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,04378576 0,10928271 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,04378576 0,10916947 ! muscle adaptation GO:0043500 14 7 0,000 0,04378576 0,10905645 ! embryonic heart tube development GO:0035050 10 7 0,000 0,04378576 0,10894368 ! retina homeostasis GO:0001895 12 7 0,000 0,04378576 0,10883113 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,04378576 0,10871882 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,04378576 0,10860674 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,04378576 0,10849489 ! protein prenylation GO:0018342 18 7 0,000 0,04378576 0,10838327 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,04378576 0,10827188 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,04378576 0,10816071 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,04378576 0,10804978 ! lipoprotein biosynthetic process GO:0042158 101 53 1,000 0,04506227 0,11108589 ! regulation of neuron apoptosis GO:0043523 100 53 1,000 0,04506227 0,11097219 ! RNA catabolic process GO:0006401 93 53 1,000 0,04506227 0,11085872 ! negative regulation of cytoskeleton organization GO:0051494 124 54 1,000 0,04660379 0,11453392 ! regulation of multicellular organism growth GO:0040014 85 55 1,000 0,04816446 0,11824866 ! skeletal muscle fiber development GO:0048741 111 56 1,000 0,04974398 0,12200206 ! positive regulation of organelle organization GO:0010638 100 56 1,000 0,04974398 0,12187782 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,04988317 0,12209452 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,04988317 0,12197044 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,04988317 0,12184661 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,04988317 0,12172304 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,04988317 0,12159971 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,04988317 0,12147663 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,04988317 0,1213538 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,04988317 0,12123122 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,04988317 0,12110889 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,04988317 0,12098681 ! oligopeptide transport GO:0006857 15 8 0,000 0,04988317 0,12086497 ! UTP metabolic process GO:0046051 8 8 0,000 0,04988317 0,12074337 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,04988317 0,12062202 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,04988317 0,12050092 GO:0046457|prostanoid biosynthetic process, ! macrophage chemotaxis GO:0048246 12 8 0,000 0,04988317 0,12038005 ! succinate metabolic process GO:0006105 14 8 0,000 0,04988317 0,12025943 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,04988317 0,12013905 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,04988317 0,12001891 ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,04988317 0,11989901 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,04988317 0,11977935 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,04988317 0,11965993 ! reflex GO:0060004 16 8 0,000 0,04988317 0,11954075 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,04988317 0,1194218 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,04988317 0,11930309 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,04988317 0,11918462 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,04988317 0,11906638 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,04988317 0,11894838 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,04988317 0,11883061 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,04988317 0,11871307 ! pigment granule organization GO:0048753 16 8 0,000 0,04988317 0,11859576 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,04988317 0,11847869 ! astrocyte differentiation GO:0048708 18 8 0,000 0,04988317 0,11836185 ! histidine metabolic process GO:0006547 16 8 0,000 0,04988317 0,11824523 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,04988317 0,11812885 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,04988317 0,1180127 ! glycine catabolic process GO:0006546 13 8 0,000 0,04988317 0,11789677 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,04988317 0,11778107 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,04988317 0,1176656 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,04988317 0,11755036 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,04988317 0,11743534 ! melanin metabolic process GO:0006582 15 8 0,000 0,04988317 0,11732054 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,04988317 0,11720597 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,04988317 0,11709162 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,04988317 0,1169775 ! macrophage activation GO:0042116 12 8 0,000 0,04988317 0,1168636 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,04988317 0,11674992 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,04988317 0,11663646 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,04988317 0,11652322 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,04988317 0,1164102 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,04988317 0,1162974 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,04988317 0,11618481 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,04988317 0,11607245 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,04988317 0,1159603 ! osteoblast development GO:0002076 16 8 0,000 0,04988317 0,11584837 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,04988317 0,11573666 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,04988317 0,11562516 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,04988317 0,11551387 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,04988317 0,1154028 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,04988317 0,11529194 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,04988317 0,1151813 ! response to UV-B GO:0010224 16 8 0,000 0,04988317 0,11507087 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,04988317 0,11496064 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,04988317 0,11485063 ! intermediate filament organization GO:0045109 12 8 0,000 0,04988317 0,11474083 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,04988317 0,11463124 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,04988317 0,11452186 ! cellular extravasation GO:0045123 12 8 0,000 0,04988317 0,11441269 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,04988317 0,11430373 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,04988317 0,11419497 ! response to antibiotic GO:0046677 11 8 0,000 0,04988317 0,11408642 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,04988317 0,11397807 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,04988317 0,11386994 ! response to tropane GO:0014073 15 8 0,000 0,04988317 0,113762 GO:0042220|response to cocaine, ! melanosome transport GO:0032402 13 8 0,000 0,04988317 0,11365427 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,04988317 0,11354675 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,04988317 0,11343943 ! mast cell activation GO:0045576 14 8 0,000 0,04988317 0,11333231 ! multicellular organismal aging GO:0010259 18 8 0,000 0,04988317 0,11322539 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,04988317 0,11311867 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,04988317 0,11301216 ! nucleosome disassembly GO:0006337 14 8 0,000 0,04988317 0,11290584 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,04988317 0,11279973 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,04988317 0,11269381 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,04988317 0,1125881 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,04988317 0,11248258 ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,04988317 0,11237726 ! intracellular lipid transport GO:0032365 13 8 0,000 0,04988317 0,11227214 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,04988317 0,11216721 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,04988317 0,11206248 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,04988317 0,11195794 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,04988317 0,1118536 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,04988317 0,11174945 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,04988317 0,1116455 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,04988317 0,11154174 ! hormone catabolic process GO:0042447 17 8 0,000 0,04988317 0,11143817 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,04988317 0,1113348 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,04988317 0,11123162 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,04988317 0,11112862 ! ATP catabolic process GO:0006200 11 8 0,000 0,04988317 0,11102582 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,04988317 0,11092321 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,04988317 0,11082079 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,04988317 0,11071855 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,04988317 0,11061651 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,04988317 0,11051465 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,04988317 0,11041298 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,04988317 0,1103115 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,04988317 0,1102102 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,04988317 0,11010909 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,04988317 0,11000817 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,04988317 0,10990743 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,04988317 0,10980687 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,04988317 0,1097065 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,04988317 0,10960631 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,04988317 0,10950631 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,04988317 0,10940648 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,04988317 0,10930684 ! muscle fiber development GO:0048747 112 57 1,000 0,05134206 0,11240128 ! maintenance of location GO:0051235 118 57 1,000 0,05134206 0,11229909 ! skeletal system morphogenesis GO:0048705 105 59 1,000 0,0545927 0,11930066 ! DNA catabolic process GO:0006308 86 59 1,000 0,0545927 0,1191924 ! establishment of organelle localization GO:0051656 109 59 1,000 0,0545927 0,11908434 ! regulation of developmental growth GO:0048638 15 9 0,000 0,05594191 0,12191687 ! axon extension GO:0048675 15 9 0,000 0,05594191 0,12180654 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,05594191 0,12169641 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,05594191 0,12158647 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,05594191 0,12147674 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,05594191 0,1213672 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,05594191 0,12125786 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,05594191 0,12114872 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,05594191 0,12103977 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,05594191 0,12093102 ! phosphate transport GO:0006817 19 9 0,000 0,05594191 0,12082247 ! reproductive behavior GO:0019098 19 9 0,000 0,05594191 0,12071411 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,05594191 0,12060594 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,05594191 0,12049797 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,05594191 0,12039019 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,05594191 0,1202826 ! GTP metabolic process GO:0046039 9 9 0,000 0,05594191 0,1201752 ! RNA methylation GO:0001510 15 9 0,000 0,05594191 0,120068 ! elastic fiber assembly GO:0048251 15 9 0,000 0,05594191 0,11996099 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,05594191 0,11985417 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,05594191 0,11974753 ! artery development GO:0060840 24 9 0,000 0,05594191 0,11964109 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,05594191 0,11953484 ! regulation of glycolysis GO:0006110 21 9 0,000 0,05594191 0,11942877 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,05594191 0,1193229 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,05594191 0,11921721 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,05594191 0,11911171 ! chemosensory behavior GO:0007635 20 9 0,000 0,05594191 0,11900639 ! microtubule bundle formation GO:0001578 21 9 0,000 0,05594191 0,11890126 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,05594191 0,11879632 ! leukocyte degranulation GO:0043299 16 9 0,000 0,05594191 0,11869156 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,05594191 0,11858698 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,05594191 0,11848259 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,05594191 0,11837839 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,05594191 0,11827437 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,05594191 0,11817052 ! protein targeting to ER GO:0045047 22 9 0,000 0,05594191 0,11806687 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,05594191 0,11796339 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,05594191 0,11786009 ! T cell selection GO:0045058 23 9 0,000 0,05594191 0,11775698 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 0,000 0,05594191 0,11765404 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,05594191 0,11755129 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,05594191 0,11744872 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,05594191 0,11734632 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,05594191 0,1172441 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,05594191 0,11714206 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,05594191 0,1170402 ! mannose metabolic process GO:0006013 13 9 0,000 0,05594191 0,11693851 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,05594191 0,116837 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,05594191 0,11673567 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,05594191 0,11663451 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,05594191 0,11653353 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,05594191 0,11643272 ! ruffle organization GO:0031529 15 9 0,000 0,05594191 0,11633209 ! retinol metabolic process GO:0042572 18 9 0,000 0,05594191 0,11623163 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,05594191 0,11613134 ! behavioral fear response GO:0001662 22 9 0,000 0,05594191 0,11603123 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,05594191 0,11593129 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,05594191 0,11583152 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,05594191 0,11573192 GO:0030204|chondroitin sulfate metabolic process, ! protein heterooligomerization GO:0051291 16 9 0,000 0,05594191 0,1156325 ! oligodendrocyte development GO:0014003 10 9 0,000 0,05594191 0,11553324 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,05594191 0,11543416 ! segment specification GO:0007379 13 9 0,000 0,05594191 0,11533524 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,05594191 0,1152365 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,05594191 0,11513792 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,05594191 0,11503951 ! response to amine stimulus GO:0014075 13 9 0,000 0,05594191 0,11494127 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,05594191 0,1148432 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,05594191 0,11474529 ! erythrocyte development GO:0048821 15 9 0,000 0,05594191 0,11464755 ! gas homeostasis GO:0033483 16 9 0,000 0,05594191 0,11454998 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,05594191 0,11445257 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,05594191 0,11435533 ! renal water homeostasis GO:0003091 14 9 0,000 0,05594191 0,11425826 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,05594191 0,11416135 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,05594191 0,1140646 ! icosanoid secretion GO:0032309 15 9 0,000 0,05594191 0,11396802 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,05594191 0,1138716 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,05594191 0,11377534 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,05594191 0,11367925 ! regulation of cell division GO:0051302 15 9 0,000 0,05594191 0,11358331 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,05594191 0,11348754 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,05594191 0,11339194 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,05594191 0,11329649 ! sterol catabolic process GO:0016127 11 9 0,000 0,05594191 0,1132012 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,05594191 0,11310607 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,05594191 0,11301111 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,05594191 0,1129163 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,05594191 0,11282165 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,05594191 0,11272716 ! musculoskeletal movement GO:0050881 14 9 0,000 0,05594191 0,11263283 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,05594191 0,11253865 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,05594191 0,11244463 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,05594191 0,11235077 ! purine base metabolic process GO:0006144 21 9 0,000 0,05594191 0,11225707 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,05594191 0,11216352 ! pigment granule transport GO:0051904 17 9 0,000 0,05594191 0,11207013 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,05594191 0,11197689 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,05594191 0,11188381 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,05594191 0,11179089 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,05594191 0,11169811 ! mitochondrion localization GO:0051646 15 9 0,000 0,05594191 0,1116055 ! regulation of neurotransmitter levels GO:0001505 97 60 1,000 0,05624466 0,11211653 ! camera-type eye development GO:0043010 116 60 1,000 0,05624466 0,11202372 ! negative regulation of response to stimulus GO:0048585 100 60 1,000 0,05624466 0,11193106 ! glycerophospholipid biosynthetic process GO:0046474 105 61 1,000 0,05791401 0,11515793 ! ear development GO:0043583 103 62 1,000 0,05960045 0,11841344 ! gonad development GO:0008406 98 62 1,000 0,05960045 0,11831574 ! detection of external stimulus GO:0009581 91 63 1,000 0,06130369 0,12159661 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,06196221 0,12280154 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 0,000 0,06196221 0,12270047 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,06196221 0,12259956 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,06196221 0,12249882 ! positive regulation of B cell proliferation GO:0030890 16 10 0,000 0,06196221 0,12239825 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,06196221 0,12229784 ! synapsis GO:0007129 13 10 0,000 0,06196221 0,1221976 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,06196221 0,12209752 ! N-glycan processing GO:0006491 20 10 0,000 0,06196221 0,1219976 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,06196221 0,12189785 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,06196221 0,12179826 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,06196221 0,12169883 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,06196221 0,12159956 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,06196221 0,12150046 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,06196221 0,12140152 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,06196221 0,12130274 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,06196221 0,12120412 ! androgen metabolic process GO:0008209 17 10 0,000 0,06196221 0,12110566 ! phospholipid efflux GO:0033700 16 10 0,000 0,06196221 0,12100736 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,06196221 0,12090922 ! lung alveolus development GO:0048286 26 10 0,000 0,06196221 0,12081124 ! pathogenesis GO:0009405 13 10 0,000 0,06196221 0,12071341 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,06196221 0,12061575 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,06196221 0,12051824 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,06196221 0,12042089 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,06196221 0,1203237 ! endoderm development GO:0007492 16 10 0,000 0,06196221 0,12022667 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,06196221 0,12012979 ! arginine catabolic process GO:0006527 13 10 0,000 0,06196221 0,12003306 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,06196221 0,1199365 ! proline metabolic process GO:0006560 13 10 0,000 0,06196221 0,11984009 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,06196221 0,11974383 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,06196221 0,11964773 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,06196221 0,11955178 ! V(D)J recombination GO:0033151 28 10 0,000 0,06196221 0,11945598 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,06196221 0,11936034 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,06196221 0,11926485 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,06196221 0,11916952 ! B cell proliferation GO:0042100 18 10 0,000 0,06196221 0,11907433 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,06196221 0,1189793 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,06196221 0,11888442 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,06196221 0,11878969 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,06196221 0,11869512 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,06196221 0,11860069 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,06196221 0,11850641 ! macroautophagy GO:0016236 17 10 0,000 0,06196221 0,11841228 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,06196221 0,11831831 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,06196221 0,11822448 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,06196221 0,1181308 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,06196221 0,11803727 ! copper ion homeostasis GO:0055070 13 10 0,000 0,06196221 0,11794388 ! regulation of bone resorption GO:0045124 25 10 0,000 0,06196221 0,11785065 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,06196221 0,11775756 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,06196221 0,11766461 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,06196221 0,11757182 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,06196221 0,11747917 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,06196221 0,11738667 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,06196221 0,11729431 ! blastoderm segmentation GO:0007350 18 10 0,000 0,06196221 0,1172021 ! response to dsRNA GO:0043331 20 10 0,000 0,06196221 0,11711003 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,06196221 0,11701811 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,06196221 0,11692633 ! melanosome localization GO:0032400 16 10 0,000 0,06196221 0,11683469 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,06196221 0,1167432 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,06196221 0,11665185 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,06196221 0,11656065 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,06196221 0,11646958 ! mRNA cleavage GO:0006379 17 10 0,000 0,06196221 0,11637866 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,06196221 0,11628788 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,06196221 0,11619725 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,06196221 0,11610675 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,06196221 0,11601639 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,06196221 0,11592618 ! salivary gland development GO:0007431 27 10 0,000 0,06196221 0,1158361 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,06196221 0,11574617 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,06196221 0,11565637 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,06196221 0,11556672 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,06196221 0,1154772 ! midbrain development GO:0030901 13 10 0,000 0,06196221 0,11538782 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,06196221 0,11529858 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,06196221 0,11520948 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,06196221 0,11512051 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,06196221 0,11503169 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,06196221 0,114943 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 0,06196221 0,11485444 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 0,06196221 0,11476602 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,06196221 0,11467774 ! blastocyst formation GO:0001825 17 10 0,000 0,06196221 0,1145896 ! cerebellar cortex development GO:0021695 15 10 0,000 0,06196221 0,11450159 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,06196221 0,11441371 ! activation of innate immune response GO:0002218 12 10 0,000 0,06196221 0,11432597 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,06196221 0,11423836 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,06196221 0,11415089 ! response to nicotine GO:0035094 20 10 0,000 0,06196221 0,11406355 ! establishment of cell polarity GO:0030010 16 10 0,000 0,06196221 0,11397635 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,06196221 0,11388928 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,06196221 0,11380234 ! localization within membrane GO:0051668 20 10 0,000 0,06196221 0,11371553 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 1,000 0,06302347 0,11557506 ! lymphocyte mediated immunity GO:0002449 114 64 1,000 0,06302347 0,11548704 ! embryonic limb morphogenesis GO:0030326 125 65 1,000 0,06475951 0,11857791 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 1,000 0,06475951 0,11848774 ! myeloid cell differentiation GO:0030099 111 65 1,000 0,06475951 0,1183977 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 1,000 0,06651152 0,12150851 ! actin filament organization GO:0007015 148 66 1,000 0,06651152 0,12141632 ! extracellular matrix organization GO:0030198 133 66 1,000 0,06651152 0,12132427 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,06794431 0,12384395 ! respiratory burst GO:0045730 17 11 0,000 0,06794431 0,1237502 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,06794431 0,12365659 ! neuron fate specification GO:0048665 17 11 0,000 0,06794431 0,12356312 ! telencephalon cell migration GO:0022029 20 11 0,000 0,06794431 0,1234698 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,06794431 0,12337661 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,06794431 0,12328357 ! thyroid gland development GO:0030878 26 11 0,000 0,06794431 0,12319067 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 0,000 0,06794431 0,1230979 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,06794431 0,12300528 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,06794431 0,12291279 ! response to pain GO:0048265 24 11 0,000 0,06794431 0,12282045 ! T cell proliferation GO:0042098 26 11 0,000 0,06794431 0,12272824 ! blood vessel remodeling GO:0001974 29 11 0,000 0,06794431 0,12263617 ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,06794431 0,12254424 ! bone resorption GO:0045453 16 11 0,000 0,06794431 0,12245244 ! peptide or protein amino-terminal blocking GO:0018409 21 11 0,000 0,06794431 0,12236079 ! ventral spinal cord development GO:0021517 21 11 0,000 0,06794431 0,12226927 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,06794431 0,12217789 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,06794431 0,12208664 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,06794431 0,12199553 ! melanocyte differentiation GO:0030318 21 11 0,000 0,06794431 0,12190456 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,06794431 0,12181372 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,06794431 0,12172302 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,06794431 0,12163245 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,06794431 0,12154202 GO:0043088|regulation of Cdc42 GTPase activity, ! lipid digestion GO:0044241 18 11 0,000 0,06794431 0,12145172 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,06794431 0,12136155 ! UV protection GO:0009650 19 11 0,000 0,06794431 0,12127152 ! adult heart development GO:0007512 14 11 0,000 0,06794431 0,12118163 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,06794431 0,12109186 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,06794431 0,12100223 ! temperature homeostasis GO:0001659 17 11 0,000 0,06794431 0,12091273 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,06794431 0,12082336 ! negative regulation of ossification GO:0030279 26 11 0,000 0,06794431 0,12073413 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,06794431 0,12064503 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,06794431 0,12055606 ! regulation of organ growth GO:0046620 13 11 0,000 0,06794431 0,12046722 ! pigment granule localization GO:0051875 20 11 0,000 0,06794431 0,12037851 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,06794431 0,12028993 ! vasoconstriction GO:0042310 18 11 0,000 0,06794431 0,12020148 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,06794431 0,12011316 ! embryonic axis specification GO:0000578 18 11 0,000 0,06794431 0,12002497 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,06794431 0,11993691 ! snRNA metabolic process GO:0016073 24 11 0,000 0,06794431 0,11984898 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,06794431 0,11976118 ! DNA methylation GO:0006306 19 11 0,000 0,06794431 0,11967351 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,06794431 0,11958596 ! zymogen activation GO:0031638 15 11 0,000 0,06794431 0,11949855 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,06794431 0,11941126 ! neuroblast proliferation GO:0007405 24 11 0,000 0,06794431 0,1193241 ! nucleosome positioning GO:0016584 15 11 0,000 0,06794431 0,11923706 ! regulation of isotype switching GO:0045191 22 11 0,000 0,06794431 0,11915015 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,06794431 0,11906337 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,06794431 0,11897672 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,06794431 0,11889019 ! acid secretion GO:0046717 18 11 0,000 0,06794431 0,11880379 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,06794431 0,11871751 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,06794431 0,11863136 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,06794431 0,11854533 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,06794431 0,11845943 ! thymus development GO:0048538 27 11 0,000 0,06794431 0,11837365 ! cholesterol efflux GO:0033344 19 11 0,000 0,06794431 0,118288 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,06794431 0,11820247 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,06794431 0,11811706 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,06794431 0,11803178 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,06794431 0,11794662 ! embryonic gut development GO:0048566 15 11 0,000 0,06794431 0,11786158 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,06794431 0,11777667 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,06794431 0,11769187 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,06794431 0,1176072 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,06794431 0,11752265 ! defense response to fungus GO:0050832 13 11 0,000 0,06794431 0,11743823 ! developmental induction GO:0031128 19 11 0,000 0,06794431 0,11735392 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,06794431 0,11726974 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,06794431 0,11718567 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,06794431 0,11710173 ! sequestering of metal ion GO:0051238 14 11 0,000 0,06794431 0,1170179 ! lamellipodium assembly GO:0030032 20 11 0,000 0,06794431 0,1169342 ! regulation of embryonic development GO:0045995 27 11 0,000 0,06794431 0,11685062 ! nucleus localization GO:0051647 19 11 0,000 0,06794431 0,11676715 ! regulation of synapse organization GO:0050807 17 11 0,000 0,06794431 0,11668381 ! regulation of cellular response to stress GO:0080135 128 67 1,000 0,06827923 0,11717535 ! negative regulation of cell growth GO:0030308 132 67 1,000 0,06827923 0,11709183 ! activation of MAPK activity GO:0000187 115 67 1,000 0,06827923 0,11700843 ! lung development GO:0030324 144 67 1,000 0,06827923 0,11692515 ! adaptive immune response GO:0002250 119 67 1,000 0,06827923 0,11684199 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! negative regulation of cell size GO:0045792 134 69 1,000 0,07186071 0,12288335 ! cAMP-mediated signaling GO:0019933 120 69 1,000 0,07186071 0,12279608 ! glycerolipid biosynthetic process GO:0045017 118 69 1,000 0,07186071 0,12270893 ! appendage morphogenesis GO:0035107 135 70 1,000 0,07367395 0,12571597 GO:0035108|limb morphogenesis, ! respiratory tube development GO:0030323 150 70 1,000 0,07367395 0,12562687 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,07388846 0,12590343 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,07388846 0,12581433 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,07388846 0,12572535 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 0,07388846 0,1256365 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,07388846 0,12554777 ! virus-host interaction GO:0019048 29 12 0,000 0,07388846 0,12545917 ! regulation of B cell proliferation GO:0030888 20 12 0,000 0,07388846 0,1253707 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,07388846 0,12528234 ! cartilage condensation GO:0001502 20 12 0,000 0,07388846 0,12519412 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,07388846 0,12510601 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,07388846 0,12501804 ! protein complex disassembly GO:0043241 27 12 0,000 0,07388846 0,12493018 GO:0043624|cellular protein complex disassembly, ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,07388846 0,12484245 ! hippocampus development GO:0021766 26 12 0,000 0,07388846 0,12475484 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,07388846 0,12466735 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,07388846 0,12457999 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,07388846 0,12449275 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,07388846 0,12440563 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,07388846 0,12431863 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,07388846 0,12423176 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,07388846 0,124145 ! drug transport GO:0015893 16 12 0,000 0,07388846 0,12405837 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,07388846 0,12397186 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,07388846 0,12388547 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,07388846 0,1237992 ! polyamine metabolic process GO:0006595 17 12 0,000 0,07388846 0,12371305 ! focal adhesion formation GO:0048041 35 12 0,000 0,07388846 0,12362701 ! mitotic spindle organization GO:0007052 21 12 0,000 0,07388846 0,1235411 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,07388846 0,12345531 ! forebrain cell migration GO:0021885 21 12 0,000 0,07388846 0,12336964 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,07388846 0,12328408 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,07388846 0,12319865 ! entry into host cell GO:0030260 32 12 0,000 0,07388846 0,12311333 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,07388846 0,12302813 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,07388846 0,12294305 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,07388846 0,12285808 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,07388846 0,12277324 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,07388846 0,12268851 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,07388846 0,12260389 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,07388846 0,1225194 ! protein homotetramerization GO:0051289 21 12 0,000 0,07388846 0,12243502 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,07388846 0,12235075 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,07388846 0,12226661 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,07388846 0,12218257 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,07388846 0,12209866 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,07388846 0,12201486 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,07388846 0,12193117 ! cranial nerve development GO:0021545 20 12 0,000 0,07388846 0,1218476 ! fucose catabolic process GO:0019317 22 12 0,000 0,07388846 0,12176414 GO:0042355|L-fucose catabolic process, ! histone acetylation GO:0016573 26 12 0,000 0,07388846 0,1216808 ! histone methylation GO:0016571 26 12 0,000 0,07388846 0,12159757 ! autonomic nervous system development GO:0048483 24 12 0,000 0,07388846 0,12151445 ! gland morphogenesis GO:0022612 29 12 0,000 0,07388846 0,12143145 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,07388846 0,12134856 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,07388846 0,12126579 ! T cell homeostasis GO:0043029 25 12 0,000 0,07388846 0,12118313 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,07388846 0,12110058 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,07388846 0,12101814 ! spleen development GO:0048536 22 12 0,000 0,07388846 0,12093581 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,07388846 0,1208536 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,07388846 0,1207715 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,07388846 0,12068951 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,07388846 0,12060763 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,07388846 0,12052586 ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,07388846 0,1204442 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,07388846 0,12036266 ! response to cold GO:0009409 17 12 0,000 0,07388846 0,12028122 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,07388846 0,1201999 ! appendage development GO:0048736 136 71 1,000 0,07550183 0,12274148 GO:0060173|limb development, ! regulation of MAPKKK cascade GO:0043408 142 71 1,000 0,07550183 0,12265861 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 1,000 0,0773441 0,12556673 ! respiratory system development GO:0060541 153 72 1,000 0,0773441 0,12548206 ! lipoprotein metabolic process GO:0042157 131 73 1,000 0,0792005 0,12840728 ! axon guidance GO:0007411 139 73 1,000 0,0792005 0,12832081 ! cGMP metabolic process GO:0046068 18 13 0,000 0,07979491 0,12919687 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,07979491 0,12910998 ! regulation of chemokine production GO:0032642 18 13 0,000 0,07979491 0,12902322 ! peroxisomal transport GO:0043574 24 13 0,000 0,07979491 0,12893656 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,07979491 0,12885003 ! lipid localization GO:0010876 28 13 0,000 0,07979491 0,12876361 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,07979491 0,12867731 ! organelle fusion GO:0048284 32 13 0,000 0,07979491 0,12859112 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,07979491 0,12850505 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,07979491 0,12841909 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,07979491 0,12833325 ! endocrine pancreas development GO:0031018 22 13 0,000 0,07979491 0,12824752 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,07979491 0,12816191 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,07979491 0,12807641 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,07979491 0,12799103 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,07979491 0,12790576 ! methionine metabolic process GO:0006555 27 13 0,000 0,07979491 0,1278206 ! plasma membrane organization GO:0007009 24 13 0,000 0,07979491 0,12773556 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,07979491 0,12765063 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,07979491 0,12756581 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,07979491 0,1274811 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,07979491 0,12739651 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,07979491 0,12731203 ! cytokine metabolic process GO:0042107 22 13 0,000 0,07979491 0,12722766 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,07979491 0,12714341 ! exocrine system development GO:0035272 32 13 0,000 0,07979491 0,12705926 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 0,07979491 0,12697523 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,07979491 0,1268913 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,07979491 0,12680749 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,07979491 0,12672379 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,07979491 0,1266402 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,07979491 0,12655672 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,07979491 0,12647335 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,07979491 0,12639009 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,07979491 0,12630694 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,07979491 0,12622389 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,07979491 0,12614096 ! ribosome assembly GO:0042255 17 13 0,000 0,07979491 0,12605814 ! regulation of monooxygenase activity GO:0032768 33 13 0,000 0,07979491 0,12597542 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,07979491 0,12589282 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,07979491 0,12581032 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,07979491 0,12572793 ! regulation of epidermis development GO:0045682 19 13 0,000 0,07979491 0,12564564 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,07979491 0,12556347 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,07979491 0,1254814 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,07979491 0,12539944 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,07979491 0,12531759 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,07979491 0,12523584 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,07979491 0,1251542 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,07979491 0,12507267 ! embryonic placenta development GO:0001892 23 13 0,000 0,07979491 0,12499124 ! insulin secretion GO:0030073 23 13 0,000 0,07979491 0,12490992 ! actin filament polymerization GO:0030041 24 13 0,000 0,07979491 0,1248287 ! acrosome reaction GO:0007340 18 13 0,000 0,07979491 0,12474759 ! regulation of transcription factor activity GO:0051090 126 74 1,000 0,08107078 0,12665993 GO:0090046|regulation of transcription regulator activity, ! neurotransmitter transport GO:0006836 123 74 1,000 0,08107078 0,12657774 ! leukocyte mediated immunity GO:0002443 128 74 1,000 0,08107078 0,12649565 ! organelle localization GO:0051640 136 74 1,000 0,08107078 0,12641367 ! rhythmic process GO:0048511 128 75 1,000 0,08295469 0,12926748 ! lymphocyte differentiation GO:0030098 167 75 1,000 0,08295469 0,12918381 ! development of primary sexual characteristics GO:0045137 124 76 1,000 0,08485199 0,13205296 ! steroid biosynthetic process GO:0006694 131 76 1,000 0,08485199 0,1319676 ! rRNA transcription GO:0009303 25 14 0,000 0,08566387 0,13314424 ! lactation GO:0007595 26 14 0,000 0,08566387 0,13305828 ! N-terminal protein amino acid modification GO:0031365 27 14 0,000 0,08566387 0,13297244 ! reproductive cellular process GO:0048610 20 14 0,000 0,08566387 0,1328867 ! tRNA modification GO:0006400 20 14 0,000 0,08566387 0,13280108 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,08566387 0,13271557 ! water transport GO:0006833 21 14 0,000 0,08566387 0,13263017 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,08566387 0,13254487 ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,08566387 0,13245969 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,08566387 0,13237462 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,08566387 0,13228965 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,08566387 0,1322048 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,08566387 0,13212005 ! palate development GO:0060021 31 14 0,000 0,08566387 0,13203541 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,08566387 0,13195088 ! regulated secretory pathway GO:0045055 23 14 0,000 0,08566387 0,13186646 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,08566387 0,13178215 ! arginine metabolic process GO:0006525 17 14 0,000 0,08566387 0,13169794 ! regulation of heart rate GO:0002027 24 14 0,000 0,08566387 0,13161384 ! organic alcohol transport GO:0015850 29 14 0,000 0,08566387 0,13152985 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,08566387 0,13144597 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,08566387 0,13136219 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,08566387 0,13127852 ! neutral amino acid transport GO:0015804 26 14 0,000 0,08566387 0,13119496 ! L-amino acid transport GO:0015807 30 14 0,000 0,08566387 0,1311115 ! bone mineralization GO:0030282 17 14 0,000 0,08566387 0,13102815 ! stem cell development GO:0048864 43 14 0,000 0,08566387 0,1309449 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,08566387 0,13086176 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,08566387 0,13077873 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,08566387 0,1306958 ! cerebellum development GO:0021549 21 14 0,000 0,08566387 0,13061298 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,08566387 0,13053026 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,08566387 0,13044764 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,08566387 0,13036513 ! cofactor transport GO:0051181 26 14 0,000 0,08566387 0,13028273 ! NADP metabolic process GO:0006739 24 14 0,000 0,08566387 0,13020043 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,08566387 0,13011823 ! intestinal absorption GO:0050892 25 14 0,000 0,08566387 0,13003614 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,08566387 0,12995415 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,08566387 0,12987226 ! male genitalia development GO:0030539 24 14 0,000 0,08566387 0,12979048 ! regulation of RNA stability GO:0043487 32 14 0,000 0,08566387 0,1297088 ! regulation of axon extension GO:0030516 37 14 0,000 0,08566387 0,12962722 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,08566387 0,12954574 ! blood coagulation GO:0007596 146 78 1,000 0,08868574 0,13403134 GO:0050817|coagulation, ! negative regulation of organelle organization GO:0010639 161 78 1,000 0,08868574 0,13394721 ! response to steroid hormone stimulus GO:0048545 137 78 1,000 0,08868574 0,13386317 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 1,000 0,09062173 0,13669961 ! positive regulation of phosphorylation GO:0042327 129 79 1,000 0,09062173 0,13661396 ! regulation of synaptic transmission GO:0050804 134 79 1,000 0,09062173 0,13652841 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,0914956 0,13775871 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,0914956 0,13767256 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,0914956 0,13758651 ! superoxide anion generation GO:0042554 20 15 0,000 0,0914956 0,13750057 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,0914956 0,13741474 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,0914956 0,13732902 ! copper ion transport GO:0006825 20 15 0,000 0,0914956 0,1372434 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,0914956 0,13715789 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,0914956 0,13707249 ! sulfate transport GO:0008272 23 15 0,000 0,0914956 0,13698719 ! response to cAMP GO:0051591 22 15 0,000 0,0914956 0,136902 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,0914956 0,13681692 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,0914956 0,13673194 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,0914956 0,13664706 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,0914956 0,13656229 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,0914956 0,13647763 ! response to hexose stimulus GO:0009746 22 15 0,000 0,0914956 0,13639307 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,0914956 0,13630862 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,0914956 0,13622427 ! pituitary gland development GO:0021983 29 15 0,000 0,0914956 0,13614002 ! vesicle coating GO:0006901 33 15 0,000 0,0914956 0,13605588 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,0914956 0,13597185 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,0914956 0,13588791 ! regulation of exocytosis GO:0017157 22 15 0,000 0,0914956 0,13580408 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,0914956 0,13572036 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,0914956 0,13563673 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,0914956 0,13555321 ! regulation of vasodilation GO:0042312 26 15 0,000 0,0914956 0,1354698 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,0914956 0,13538648 ! mRNA splice site selection GO:0006376 38 15 0,000 0,0914956 0,13530327 ! tissue regeneration GO:0042246 26 15 0,000 0,0914956 0,13522016 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,0914956 0,13513715 ! water homeostasis GO:0030104 27 15 0,000 0,0914956 0,13505424 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,0914956 0,13497144 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,0914956 0,13488874 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,0914956 0,13480613 ! heme biosynthetic process GO:0006783 29 15 0,000 0,0914956 0,13472363 ! cell killing GO:0001906 29 15 0,000 0,0914956 0,13464123 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,0914956 0,13455894 ! detection of bacterium GO:0016045 18 15 0,000 0,0914956 0,13447674 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,0914956 0,13439464 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,0914956 0,13431264 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,0914956 0,13423074 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,0914956 0,13414894 ! peptide hormone processing GO:0016486 23 15 0,000 0,0914956 0,13406725 ! regulation of adenylate cyclase activity GO:0045761 156 80 1,000 0,09257013 0,13555917 ! response to metal ion GO:0010038 140 80 1,000 0,09257013 0,13547672 ! protein import into nucleus GO:0006606 158 80 1,000 0,09257013 0,13539436 ! T cell activation GO:0042110 168 81 1,000 0,09453071 0,13817794 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 1,000 0,09453071 0,13809404 GO:0045937|positive regulation of phosphate metabolic process, ! intracellular protein transmembrane transport GO:0065002 153 81 1,000 0,09453071 0,13801024 ! nuclear import GO:0051170 161 81 1,000 0,09453071 0,13792655 ! regulation of cAMP biosynthetic process GO:0030817 161 82 1,000 0,09650324 0,14071927 ! response to drug GO:0042493 143 82 1,000 0,09650324 0,14063404 ! regulation of cyclase activity GO:0031279 159 82 1,000 0,09650324 0,14054891 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,09729033 0,14160952 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,09729033 0,1415239 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,09729033 0,14143839 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,09729033 0,14135298 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,09729033 0,14126767 ! bone remodeling GO:0046849 27 16 0,000 0,09729033 0,14118247 ! filopodium assembly GO:0046847 32 16 0,000 0,09729033 0,14109737 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,09729033 0,14101237 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,09729033 0,14092747 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,09729033 0,14084268 ! startle response GO:0001964 28 16 0,000 0,09729033 0,14075799 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,09729033 0,14067339 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,09729033 0,14058891 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,09729033 0,14050452 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,09729033 0,14042023 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,09729033 0,14033605 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,09729033 0,14025196 ! protein polyubiquitination GO:0000209 34 16 0,000 0,09729033 0,14016798 ! glutamate metabolic process GO:0006536 22 16 0,000 0,09729033 0,1400841 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,09729033 0,14000032 ! response to osmotic stress GO:0006970 25 16 0,000 0,09729033 0,13991663 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,09729033 0,13983305 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,09729033 0,13974957 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,09729033 0,13966619 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,09729033 0,1395829 ! intermediate filament-based process GO:0045103 32 16 0,000 0,09729033 0,13949972 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,09729033 0,13941663 ! negative regulation of immune response GO:0050777 35 16 0,000 0,09729033 0,13933365 ! axon cargo transport GO:0008088 43 16 0,000 0,09729033 0,13925076 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,09729033 0,13916797 ! DNA replication initiation GO:0006270 27 16 0,000 0,09729033 0,13908528 ! neuron recognition GO:0008038 35 16 0,000 0,09729033 0,13900269 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,09729033 0,1389202 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,09729033 0,1388378 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,09729033 0,1387555 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,09729033 0,1386733 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,09729033 0,1385912 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,09729033 0,13850919 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,09729033 0,13842728 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,09729033 0,13834547 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,09729033 0,13826375 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,09729033 0,13818213 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,09729033 0,13810061 ! defense response to virus GO:0051607 37 16 0,000 0,09729033 0,13801918 ! regulation of lyase activity GO:0051339 160 83 1,000 0,09848749 0,13963518 ! regulation of cAMP metabolic process GO:0030814 168 84 1,000 0,10048324 0,14238084 ! hemostasis GO:0007599 158 84 1,000 0,10048324 0,14229704 ! negative regulation of growth GO:0045926 155 84 1,000 0,10048324 0,14221333 ! regulation of transmission of nerve impulse GO:0051969 141 84 1,000 0,10048324 0,14212973 ! response to unfolded protein GO:0006986 131 85 1,000 0,10249025 0,14488339 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,10304828 0,14558671 ! metencephalon development GO:0022037 30 17 0,000 0,10304828 0,14550128 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,10304828 0,14541594 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,10304828 0,1453307 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,10304828 0,14524556 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,10304828 0,14516052 ! gene silencing by RNA GO:0031047 36 17 0,000 0,10304828 0,14507558 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,10304828 0,14499074 ! glial cell development GO:0021782 27 17 0,000 0,10304828 0,144906 ! limbic system development GO:0021761 36 17 0,000 0,10304828 0,14482136 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,10304828 0,14473682 ! adult walking behavior GO:0007628 33 17 0,000 0,10304828 0,14465238 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,10304828 0,14456803 ! heart looping GO:0001947 30 17 0,000 0,10304828 0,14448378 ! myoblast differentiation GO:0045445 45 17 0,000 0,10304828 0,14439963 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,10304828 0,14431558 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,10304828 0,14423163 ! glycine metabolic process GO:0006544 28 17 0,000 0,10304828 0,14414778 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 0,000 0,10304828 0,14406402 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,10304828 0,14398036 ! NAD metabolic process GO:0019674 29 17 0,000 0,10304828 0,14389679 ! membrane budding GO:0006900 37 17 0,000 0,10304828 0,14381333 ! DNA integration GO:0015074 29 17 0,000 0,10304828 0,14372996 ! regulation of protein binding GO:0043393 33 17 0,000 0,10304828 0,14364668 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,10304828 0,14356351 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,10304828 0,14348042 ! genitalia development GO:0048806 30 17 0,000 0,10304828 0,14339744 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,10304828 0,14331455 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,10304828 0,14323176 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,10304828 0,14314906 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,10304828 0,14306646 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,10304828 0,14298395 ! steroid catabolic process GO:0006706 31 17 0,000 0,10304828 0,14290154 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,10304828 0,14281922 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,10304828 0,142737 ! organic cation transport GO:0015695 31 17 0,000 0,10304828 0,14265488 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,10304828 0,14257284 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,10304828 0,1424909 ! microspike assembly GO:0030035 36 17 0,000 0,10304828 0,14240906 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,10304828 0,14232731 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,10304828 0,14224565 ! response to inorganic substance GO:0010035 153 86 1,000 0,1045083 0,14417831 ! tube morphogenesis GO:0035239 176 86 1,000 0,1045083 0,14409569 ! amine transport GO:0015837 155 86 1,000 0,1045083 0,14401316 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 1,000 0,10653718 0,14672494 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! protein localization in nucleus GO:0034504 176 87 1,000 0,10653718 0,146641 ! positive regulation of protein modification process GO:0031401 136 88 1,000 0,10857667 0,14936276 ! regulation of DNA binding GO:0051101 155 88 1,000 0,10857667 0,14927741 ! regulation of neurological system process GO:0031644 148 88 1,000 0,10857667 0,14919216 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,1087697 0,14937209 ! neuron maturation GO:0042551 42 18 0,000 0,1087697 0,14928688 ! phosphoinositide phosphorylation GO:0046854 33 18 0,000 0,1087697 0,14920177 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,1087697 0,14911676 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,1087697 0,14903184 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,1087697 0,14894702 ! memory GO:0007613 31 18 0,000 0,1087697 0,14886229 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,1087697 0,14877766 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,1087697 0,14869313 ! patterning of blood vessels GO:0001569 39 18 0,000 0,1087697 0,14860869 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,1087697 0,14852435 GO:0042744|hydrogen peroxide catabolic process, ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,1087697 0,14844011 ! glutamine metabolic process GO:0006541 29 18 0,000 0,1087697 0,14835596 ! response to retinoic acid GO:0032526 26 18 0,000 0,1087697 0,1482719 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,1087697 0,14818794 ! response to fungus GO:0009620 21 18 0,000 0,1087697 0,14810408 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,1087697 0,14802031 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,1087697 0,14793664 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,1087697 0,14785306 ! vitamin transport GO:0051180 27 18 0,000 0,1087697 0,14776957 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,1087697 0,14768618 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,1087697 0,14760288 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,1087697 0,14751968 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,1087697 0,14743657 ! nerve development GO:0021675 28 18 0,000 0,1087697 0,14735355 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,1087697 0,14727063 ! regulation of cell morphogenesis GO:0022604 215 89 1,000 0,11062655 0,14970049 ! ossification GO:0001503 188 90 1,000 0,1126866 0,15240245 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 1,000 0,1126866 0,15231683 ! regulation of cell cycle process GO:0010564 149 90 1,000 0,1126866 0,1522313 ! protein secretion GO:0009306 39 19 0,000 0,11445482 0,15453327 ! positive regulation of translation GO:0045727 30 19 0,000 0,11445482 0,1544466 ! negative regulation of defense response GO:0031348 25 19 0,000 0,11445482 0,15436003 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,11445482 0,15427355 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,11445482 0,15418717 ! skin development GO:0043588 36 19 0,000 0,11445482 0,15410089 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,11445482 0,1540147 ! lipid phosphorylation GO:0046834 35 19 0,000 0,11445482 0,15392861 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,11445482 0,15384262 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,11445482 0,15375672 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,11445482 0,15367092 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,11445482 0,15358522 ! cerebral cortex development GO:0021987 36 19 0,000 0,11445482 0,1534996 ! pigmentation during development GO:0048066 41 19 0,000 0,11445482 0,15341409 ! response to vitamin A GO:0033189 27 19 0,000 0,11445482 0,15332867 ! heme metabolic process GO:0042168 36 19 0,000 0,11445482 0,15324334 ! actin filament bundle formation GO:0051017 42 19 0,000 0,11445482 0,15315811 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,11445482 0,15307298 ! plasma membrane fusion GO:0045026 28 19 0,000 0,11445482 0,15298794 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,11445482 0,15290299 ! peptide cross-linking GO:0018149 37 19 0,000 0,11445482 0,15281814 ! protein export from nucleus GO:0006611 36 19 0,000 0,11445482 0,15273338 ! heart process GO:0003015 30 19 0,000 0,11445482 0,15264872 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,11445482 0,15256415 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,11445482 0,15247967 ! visual learning GO:0008542 36 19 0,000 0,11445482 0,15239529 ! G1 phase GO:0051318 40 19 0,000 0,11445482 0,152311 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,11445482 0,15222681 ! cell-cell junction organization GO:0045216 35 19 0,000 0,11445482 0,1521427 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,11445482 0,15205869 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,11445482 0,15197477 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,11445482 0,15189095 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,11445482 0,15180722 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,11445482 0,15172358 ! cilium assembly GO:0042384 37 19 0,000 0,11445482 0,15164003 ! peptide hormone secretion GO:0030072 31 19 0,000 0,11445482 0,15155657 ! bone development GO:0060348 189 91 1,000 0,11475661 0,15187261 ! response to protein stimulus GO:0051789 149 91 1,000 0,11475661 0,15178912 ! phospholipid biosynthetic process GO:0008654 167 92 1,000 0,11683639 0,15445513 ! regulation of nucleotide metabolic process GO:0006140 182 93 1,000 0,11892571 0,15713083 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,12010385 0,15860037 ! positive regulation of ossification GO:0045778 47 20 0,000 0,12010385 0,15851337 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,12010385 0,15842646 ! protein amino acid acetylation GO:0006473 39 20 0,000 0,12010385 0,15833965 ! cAMP metabolic process GO:0046058 36 20 0,000 0,12010385 0,15825294 ! response to vitamin GO:0033273 31 20 0,000 0,12010385 0,15816632 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,12010385 0,1580798 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,12010385 0,15799337 ! retinoid metabolic process GO:0001523 32 20 0,000 0,12010385 0,15790703 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,12010385 0,15782079 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,12010385 0,15773465 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,12010385 0,15764859 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 0,000 0,12010385 0,15756263 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,12010385 0,15747677 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,12010385 0,157391 ! body fluid secretion GO:0007589 31 20 0,000 0,12010385 0,15730532 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,12010385 0,15721973 ! peptide secretion GO:0002790 35 20 0,000 0,12010385 0,15713424 ! stem cell differentiation GO:0048863 53 20 0,000 0,12010385 0,15704884 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,12010385 0,15696354 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,12010385 0,15687832 ! sensory perception of pain GO:0019233 30 20 0,000 0,12010385 0,1567932 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,12010385 0,15670817 ! diencephalon development GO:0021536 34 20 0,000 0,12010385 0,15662324 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,12010385 0,15653839 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,12010385 0,15645364 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,12010385 0,15636898 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,12010385 0,15628441 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,12010385 0,15619993 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,12010385 0,15611554 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,12010385 0,15603125 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,12010385 0,15594704 ! regulation of glucose import GO:0046324 29 20 0,000 0,12010385 0,15586293 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,12010385 0,15577891 ! actin filament-based movement GO:0030048 43 20 0,000 0,12010385 0,15569497 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,12010385 0,15561113 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,12010385 0,15552738 ! negative regulation of translation GO:0017148 29 20 0,000 0,12010385 0,15544372 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,12010385 0,15536015 ! biogenic amine metabolic process GO:0006576 155 94 1,000 0,12102437 0,15646676 ! regulation of T cell activation GO:0050863 158 94 1,000 0,12102437 0,15638273 ! interphase of mitotic cell cycle GO:0051329 209 95 1,000 0,12313218 0,15902095 ! mRNA transport GO:0051028 169 96 1,000 0,12524893 0,16166788 ! detection of stimulus GO:0051606 151 96 1,000 0,12524893 0,16158119 ! regulation of cell killing GO:0031341 42 21 0,000 0,12571704 0,16209818 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,12571704 0,16201135 ! hormone secretion GO:0046879 38 21 0,000 0,12571704 0,16192462 ! glycerol metabolic process GO:0006071 34 21 0,000 0,12571704 0,16183799 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,12571704 0,16175144 ! axis specification GO:0009798 38 21 0,000 0,12571704 0,16166499 ! ovarian follicle development GO:0001541 35 21 0,000 0,12571704 0,16157863 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,12571704 0,16149236 ! smooth muscle contraction GO:0006939 46 21 0,000 0,12571704 0,16140619 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,12571704 0,1613201 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,12571704 0,16123411 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,12571704 0,16114821 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,12571704 0,1610624 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,12571704 0,16097669 ! cytolysis GO:0019835 24 21 0,000 0,12571704 0,16089106 ! vasodilation GO:0042311 39 21 0,000 0,12571704 0,16080553 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,12571704 0,16072008 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,12571704 0,16063473 ! DNA modification GO:0006304 34 21 0,000 0,12571704 0,16054947 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,12571704 0,16046429 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,12571704 0,16037921 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,12571704 0,16029422 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,12571704 0,16020932 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,12571704 0,16012451 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,12571704 0,16003979 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,12571704 0,15995515 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,12571704 0,15987061 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,12571704 0,15978616 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,12571704 0,15970179 ! collagen catabolic process GO:0030574 28 21 0,000 0,12571704 0,15961752 ! sperm-egg recognition GO:0035036 21 21 0,000 0,12571704 0,15953333 ! gut development GO:0048565 39 21 0,000 0,12571704 0,15944923 ! protein ubiquitination GO:0016567 217 97 1,000 0,12737442 0,16146621 ! interphase GO:0051325 213 98 1,000 0,12950847 0,16408498 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,1312946 0,16626043 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,1312946 0,16617297 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,1312946 0,1660856 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,1312946 0,16599832 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,1312946 0,16591114 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,1312946 0,16582405 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,1312946 0,16573705 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,1312946 0,16565014 ! regeneration GO:0031099 41 22 0,000 0,1312946 0,16556332 ! keratinization GO:0031424 28 22 0,000 0,1312946 0,16547659 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,1312946 0,16538995 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,1312946 0,16530341 ! sensory perception of taste GO:0050909 28 22 0,000 0,1312946 0,16521695 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,1312946 0,16513059 ! vacuolar transport GO:0007034 36 22 0,000 0,1312946 0,16504431 ! lysosome organization GO:0007040 41 22 0,000 0,1312946 0,16495813 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,1312946 0,16487203 ! fucose metabolic process GO:0006004 39 22 0,000 0,1312946 0,16478603 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,1312946 0,16470011 ! ureteric bud development GO:0001657 43 22 0,000 0,1312946 0,16461428 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,1312946 0,16452855 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,1312946 0,1644429 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,1312946 0,16435734 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,1312946 0,16427187 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,1312946 0,16418649 ! sarcomere organization GO:0045214 30 22 0,000 0,1312946 0,1641012 ! positive regulation of B cell activation GO:0050871 38 22 0,000 0,1312946 0,164016 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,1312946 0,16393088 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,1312946 0,16384586 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,1312946 0,16376092 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 1,000 0,13165086 0,16412019 ! skeletal muscle tissue development GO:0007519 186 99 1,000 0,13165086 0,1640352 GO:0060538|skeletal muscle organ development, ! positive regulation of DNA replication GO:0045740 43 23 0,000 0,13683677 0,17040852 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,13683677 0,17032036 ! gluconeogenesis GO:0006094 33 23 0,000 0,13683677 0,1702323 ! viral genome replication GO:0019079 41 23 0,000 0,13683677 0,17014432 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,13683677 0,17005644 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,13683677 0,16996864 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,13683677 0,16988094 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,13683677 0,16979333 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,13683677 0,1697058 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,13683677 0,16961837 ! visual behavior GO:0007632 42 23 0,000 0,13683677 0,16953103 ! response to ethanol GO:0045471 46 23 0,000 0,13683677 0,16944378 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,13683677 0,16935661 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! peroxisome organization GO:0007031 37 23 0,000 0,13683677 0,16926954 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,13683677 0,16918256 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,13683677 0,16909566 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,13683677 0,16900886 ! sex determination GO:0007530 47 23 0,000 0,13683677 0,16892214 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,13683677 0,16883552 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,13683677 0,16874898 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,13683677 0,16866253 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,13683677 0,16857617 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,13683677 0,1684899 ! platelet activation GO:0030168 37 23 0,000 0,13683677 0,16840371 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,13683677 0,16831762 ! hormone transport GO:0009914 40 23 0,000 0,13683677 0,16823161 ! cell-cell recognition GO:0009988 25 23 0,000 0,13683677 0,16814569 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,13683677 0,16805986 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,13683677 0,16797411 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,13683677 0,16788845 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,13683677 0,16780288 ! positive regulation of fibroblast proliferation GO:0048146 43 24 0,000 0,14234376 0,17446718 ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,14234376 0,17437835 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,14234376 0,17428961 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,14234376 0,17420095 ! vesicle docking GO:0048278 47 24 0,000 0,14234376 0,17411239 ! spinal cord development GO:0021510 47 24 0,000 0,14234376 0,17402392 ! vacuole organization GO:0007033 43 24 0,000 0,14234376 0,17393554 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,14234376 0,17384725 ! digestive system process GO:0022600 39 24 0,000 0,14234376 0,17375904 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,14234376 0,17367093 ! regulation of behavior GO:0050795 43 24 0,000 0,14234376 0,17358291 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,14234376 0,17349497 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,14234376 0,17340713 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,14234376 0,17331937 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 47 24 0,000 0,14234376 0,1732317 ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,14234376 0,17314412 ! pallium development GO:0021543 49 24 0,000 0,14234376 0,17305663 ! pentose metabolic process GO:0019321 35 24 0,000 0,14234376 0,17296923 ! regulation of oxidoreductase activity GO:0051341 46 24 0,000 0,14234376 0,17288192 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,14234376 0,17279469 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,14234376 0,17270755 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,14234376 0,1726205 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,14234376 0,17253354 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,14234376 0,17244666 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,14234376 0,17235988 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,14234376 0,17227318 ! regulation of amine transport GO:0051952 40 24 0,000 0,14234376 0,17218656 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,14781579 0,17871598 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 0,000 0,14781579 0,17862622 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,14781579 0,17853654 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,14781579 0,17844696 ! phototransduction GO:0007602 33 25 0,000 0,14781579 0,17835747 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,14781579 0,17826807 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 0,000 0,14781579 0,17817876 ! sperm motility GO:0030317 31 25 0,000 0,14781579 0,17808953 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,14781579 0,1780004 ! neural crest cell development GO:0014032 54 25 0,000 0,14781579 0,17791135 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,14781579 0,1778224 ! interaction with host GO:0051701 62 25 0,000 0,14781579 0,17773353 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,14781579 0,17764475 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,14781579 0,17755606 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,14781579 0,17746746 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 0,000 0,14781579 0,17737895 ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,14781579 0,17729053 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,14781579 0,17720219 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,14781579 0,17711394 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,14781579 0,17702578 ! telomere organization GO:0032200 43 25 0,000 0,14781579 0,17693771 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,14781579 0,17684972 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,14781579 0,17676183 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,1532531 0,18317285 ! embryonic pattern specification GO:0009880 44 26 0,000 0,1532531 0,1830819 ! initiation of viral infection GO:0019059 57 26 0,000 0,1532531 0,18299104 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,1532531 0,18290027 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,1532531 0,18280959 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,1532531 0,182719 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,1532531 0,1826285 ! molting cycle process GO:0022404 50 26 0,000 0,1532531 0,18253809 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,1532531 0,18244777 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,1532531 0,18235754 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,1532531 0,1822674 ! insulin receptor signaling pathway GO:0008286 64 26 0,000 0,1532531 0,18217735 ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,1532531 0,18208738 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 0,000 0,1532531 0,18199751 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 0,000 0,1532531 0,18190772 GO:0045936|negative regulation of phosphate metabolic process, ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,1532531 0,18181802 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,1532531 0,18172841 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,1532531 0,18163889 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,1532531 0,18154946 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,1532531 0,18146011 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,1532531 0,18137086 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,1532531 0,18128169 ! leukocyte proliferation GO:0070661 52 26 0,000 0,1532531 0,1811926 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,1532531 0,18110361 ! neuron fate commitment GO:0048663 48 27 0,000 0,15865589 0,1873962 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,15865589 0,18730425 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,15865589 0,18721239 ! iron ion transport GO:0006826 59 27 0,000 0,15865589 0,18712062 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 0,000 0,15865589 0,18702894 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,15865589 0,18693735 ! protein amino acid acylation GO:0043543 55 27 0,000 0,15865589 0,18684585 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,15865589 0,18675444 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,15865589 0,18666311 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,15865589 0,18657188 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,15865589 0,18648074 ! autophagy GO:0006914 41 27 0,000 0,15865589 0,18638968 ! male gonad development GO:0008584 44 27 0,000 0,15865589 0,18629872 ! primary neural tube formation GO:0014020 51 27 0,000 0,15865589 0,18620784 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,15865589 0,18611705 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,15865589 0,18602635 ! glutathione metabolic process GO:0006749 39 27 0,000 0,15865589 0,18593574 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,15865589 0,18584521 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,15865589 0,18575478 ! circadian rhythm GO:0007623 50 28 0,000 0,16402439 0,19194682 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,16402439 0,19185351 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,16402439 0,19176029 ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,16402439 0,19166715 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,16402439 0,19157411 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,16402439 0,19148116 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,16402439 0,1913883 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,16402439 0,19129553 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,16402439 0,19120284 ! synaptogenesis GO:0007416 42 28 0,000 0,16402439 0,19111025 ! peptidyl-tyrosine modification GO:0018212 50 28 0,000 0,16402439 0,19101775 ! lipid oxidation GO:0034440 43 28 0,000 0,16402439 0,19092534 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,16402439 0,19083301 ! translational initiation GO:0006413 65 29 0,000 0,1693588 0,19694407 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,1693588 0,19684893 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,1693588 0,19675388 ! complement activation, classical pathway GO:0006958 48 29 0,000 0,1693588 0,19665892 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,1693588 0,19656405 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,1693588 0,19646928 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,1693588 0,19637459 ! detection of light stimulus GO:0009583 38 29 0,000 0,1693588 0,19628 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,1693588 0,1961855 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,1693588 0,19609109 ! regulation of coagulation GO:0050818 46 29 0,000 0,1693588 0,19599677 ! zinc ion transport GO:0006829 45 30 0,000 0,17465936 0,20203385 ! membrane docking GO:0022406 61 30 0,000 0,17465936 0,20193677 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,17465936 0,20183978 ! cell junction assembly GO:0034329 78 30 0,000 0,17465936 0,20174288 ! regulation of innate immune response GO:0045088 51 30 0,000 0,17465936 0,20164607 ! acute-phase response GO:0006953 49 30 0,000 0,17465936 0,20154936 ! myofibril assembly GO:0030239 47 30 0,000 0,17465936 0,20145274 GO:0055002|striated muscle cell development, ! determination of left/right symmetry GO:0007368 47 30 0,000 0,17465936 0,20135621 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,17465936 0,20125978 ! phospholipid transport GO:0015914 51 30 0,000 0,17465936 0,20116344 ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,17465936 0,20106719 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,17465936 0,20097103 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,17465936 0,20087496 ! eye morphogenesis GO:0048592 60 30 0,000 0,17465936 0,20077899 ! regulation of B cell activation GO:0050864 50 30 0,000 0,17465936 0,2006831 ! response to heat GO:0009408 50 30 0,000 0,17465936 0,20058731 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,17992627 0,2065375 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,17992627 0,20643901 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,17992627 0,20634061 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,17992627 0,2062423 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,17992627 0,20614409 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,17992627 0,20604598 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,17992627 0,20594795 GO:0055092|sterol homeostasis, ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,17992627 0,20585002 ! ovulation cycle process GO:0022602 49 31 0,000 0,17992627 0,20575218 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,17992627 0,20565444 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,17992627 0,20555679 ! peptide transport GO:0015833 55 31 0,000 0,17992627 0,20545923 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,17992627 0,20536176 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,17992627 0,20526439 ! mesoderm formation GO:0001707 69 31 0,000 0,17992627 0,20516711 ! natural killer cell activation GO:0030101 45 31 0,000 0,17992627 0,20506992 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,17992627 0,20497282 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,17992627 0,20487581 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,17992627 0,2047789 ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,17992627 0,20468208 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,18515973 0,21053607 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,18515973 0,21043662 ! cholesterol transport GO:0030301 56 32 0,000 0,18515973 0,21033726 ! spliceosome assembly GO:0000245 67 32 0,000 0,18515973 0,210238 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,18515973 0,21013883 ! metanephros development GO:0001656 74 32 0,000 0,18515973 0,21003976 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,18515973 0,20994077 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,18515973 0,20984188 ! muscle cell development GO:0055001 49 32 0,000 0,18515973 0,20974309 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,18515973 0,20964439 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,18515973 0,20954578 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,18515973 0,20944726 ! ovulation cycle GO:0042698 51 32 0,000 0,18515973 0,20934884 ! BMP signaling pathway GO:0030509 64 32 0,000 0,18515973 0,2092505 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,18515973 0,20915226 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,18515973 0,20905412 ! post-embryonic development GO:0009791 69 33 0,000 0,19035998 0,21482463 ! protein targeting to membrane GO:0006612 68 33 0,000 0,19035998 0,21472391 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,19035998 0,21462329 ! ceramide metabolic process GO:0006672 64 33 0,000 0,19035998 0,21452277 ! formation of primary germ layer GO:0001704 72 33 0,000 0,19035998 0,21442234 ! cell fate specification GO:0001708 52 33 0,000 0,19035998 0,214322 ! sterol transport GO:0015918 57 33 0,000 0,19035998 0,21422175 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,19035998 0,2141216 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,19035998 0,21402155 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,19035998 0,21392158 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,19552721 0,2196258 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,19552721 0,21952331 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,19552721 0,21942092 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,19552721 0,21931863 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,19552721 0,21921643 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,19552721 0,21911433 ! spermatid development GO:0007286 63 34 0,000 0,19552721 0,21901232 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,19552721 0,2189104 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,19552721 0,21880859 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 0,000 0,19552721 0,21870686 ! regulation of muscle development GO:0048634 70 35 0,000 0,20066163 0,22434567 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,20066163 0,22424146 ! negative regulation of secretion GO:0051048 63 35 0,000 0,20066163 0,22413736 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,20066163 0,22403335 ! odontogenesis GO:0042476 66 35 0,000 0,20066163 0,22392944 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,20066163 0,22382563 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,20066163 0,22372191 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,20066163 0,22361828 ! calcium-mediated signaling GO:0019722 62 35 0,000 0,20066163 0,22351476 ! cytokine production GO:0001816 59 35 0,000 0,20066163 0,22341133 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,20066163 0,22330799 ! neural tube formation GO:0001841 67 35 0,000 0,20066163 0,22320475 ! vesicle localization GO:0051648 64 35 0,000 0,20066163 0,22310161 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,20576345 0,22866829 ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,20576345 0,22856272 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,20576345 0,22845725 ! cell junction organization GO:0034330 86 36 0,000 0,20576345 0,22835187 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,20576345 0,22824659 ! positive regulation of cell development GO:0010720 80 36 0,000 0,20576345 0,22814141 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,20576345 0,22803632 ! aerobic respiration GO:0009060 55 36 0,000 0,20576345 0,22793133 ! androgen receptor signaling pathway GO:0030521 74 36 0,000 0,20576345 0,22782644 ! embryonic organ development GO:0048568 57 36 0,000 0,20576345 0,22772164 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,20576345 0,22761694 ! RNA export from nucleus GO:0006405 56 37 0,000 0,21083287 0,2331176 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,21083287 0,23301052 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,21083287 0,23290353 ! sister chromatid segregation GO:0000819 58 37 0,000 0,21083287 0,23279665 ! actomyosin structure organization GO:0031032 62 37 0,000 0,21083287 0,23268986 ! organic anion transport GO:0015711 68 37 0,000 0,21083287 0,23258317 ! tissue remodeling GO:0048771 76 37 0,000 0,21083287 0,23247658 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,21083287 0,23237008 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,21083287 0,23226369 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,21083287 0,23215739 GO:0015986|ATP synthesis coupled proton transport, ! pigment metabolic process GO:0042440 80 37 0,000 0,21083287 0,23205119 ! spermatid differentiation GO:0048515 66 37 0,000 0,21083287 0,23194508 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,21587011 0,23737819 GO:0006956|complement activation, ! regulation of neuron projection development GO:0010975 91 38 0,000 0,21587011 0,23726975 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,21587011 0,23716141 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,21587011 0,23705317 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,21587011 0,23694502 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,21587011 0,23683698 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,21587011 0,23672903 ! positive regulation of leukocyte proliferation GO:0070665 62 38 0,000 0,21587011 0,23662118 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,21587011 0,23651343 ! learning GO:0007612 77 39 0,000 0,22087536 0,24188717 ! organic ether metabolic process GO:0018904 55 39 0,000 0,22087536 0,24177712 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,22087536 0,24166718 ! segmentation GO:0035282 67 39 0,000 0,22087536 0,24155733 ! ion transmembrane transport GO:0034220 66 39 0,000 0,22087536 0,24144758 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,22087536 0,24133793 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,22087536 0,24122838 ! RNA modification GO:0009451 57 39 0,000 0,22087536 0,24111893 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,22584883 0,24643641 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,22584883 0,2463247 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,22584883 0,24621309 ! mesenchymal cell development GO:0014031 87 40 0,000 0,22584883 0,24610158 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,22584883 0,24599017 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,23079071 0,25125903 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,23079071 0,25114539 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,23079071 0,25103185 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,23079071 0,25091841 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,23079071 0,25080508 ! positive regulation of transcription factor activity GO:0051091 62 42 0,000 0,23570121 0,25602579 GO:0090047|positive regulation of transcription regulator activity, ! regulation of tube size GO:0035150 71 42 0,000 0,23570121 0,25591025 GO:0050880|regulation of blood vessel size, ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,23570121 0,25579482 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,23570121 0,25567949 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,23570121 0,25556427 ! neuron migration GO:0001764 79 42 0,000 0,23570121 0,25544915 ! regulation of protein secretion GO:0050708 71 42 0,000 0,23570121 0,25533414 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,24058053 0,26050258 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,24058053 0,2603854 ! glucose transport GO:0015758 65 43 0,000 0,24058053 0,26026832 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,24058053 0,26015135 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,24058053 0,26003448 ! neural tube development GO:0021915 77 43 0,000 0,24058053 0,25991771 ! striated muscle contraction GO:0006941 77 43 0,000 0,24058053 0,25980105 ! phagocytosis GO:0006909 90 43 0,000 0,24058053 0,2596845 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,24058053 0,25956805 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,24542885 0,26468033 ! hexose transport GO:0008645 67 44 0,000 0,24542885 0,26456174 GO:0015749|monosaccharide transport, ! male sex differentiation GO:0046661 76 44 0,000 0,24542885 0,26444327 ! biopolymer methylation GO:0043414 84 44 0,000 0,24542885 0,26432489 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,24542885 0,26420663 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,24542885 0,26408847 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,25024638 0,2691519 ! leukocyte migration GO:0050900 68 45 0,000 0,25024638 0,26903163 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,25024638 0,26891148 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,25024638 0,26879143 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,25024638 0,26867149 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,25024638 0,26855165 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,25024638 0,26843192 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,25503332 0,27344481 ! positive regulation of defense response GO:0031349 76 47 0,000 0,25978985 0,27842066 ! positive regulation of DNA binding GO:0043388 73 47 0,000 0,25978985 0,27829669 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,25978985 0,27817284 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,25978985 0,2780491 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,25978985 0,27792547 ! methylation GO:0032259 90 47 0,000 0,25978985 0,27780194 ! Notch signaling pathway GO:0007219 96 48 0,000 0,26451616 0,28273029 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,26451616 0,28260475 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,26451616 0,28247931 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,26451616 0,28235399 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,26451616 0,28222878 ! regulation of ion transport GO:0043269 77 49 0,000 0,26921246 0,28711222 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,26921246 0,28698501 ! peptide metabolic process GO:0006518 76 49 0,000 0,26921246 0,28685792 ! response to temperature stimulus GO:0009266 76 49 0,000 0,26921246 0,28673093 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,26921246 0,28660406 ! endocrine system development GO:0035270 104 49 0,000 0,26921246 0,2864773 ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,26921246 0,28635065 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,27387892 0,29118546 ! neuromuscular process GO:0050905 99 50 0,000 0,27387892 0,29105684 ! regulation of ossification GO:0030278 117 50 0,000 0,27387892 0,29092834 ! inner ear development GO:0048839 79 50 0,000 0,27387892 0,29079995 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,27387892 0,29067167 ! positive regulation of binding GO:0051099 78 51 0,000 0,27851574 0,29546247 ! viral infectious cycle GO:0019058 99 51 0,000 0,27851574 0,29533225 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,27851574 0,29520215 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,27851574 0,29507216 ! excretion GO:0007588 83 51 0,000 0,27851574 0,29494229 ! chromatin remodeling GO:0006338 109 51 0,000 0,27851574 0,29481253 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,27851574 0,29468288 ! vesicle organization GO:0016050 107 51 0,000 0,27851574 0,29455335 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,27851574 0,29442393 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,2831231 0,29916302 ! positive regulation of growth GO:0045927 90 52 0,000 0,2831231 0,29903169 ! cartilage development GO:0051216 90 52 0,000 0,2831231 0,29890048 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,2877012 0,30360047 ! regulation of translational initiation GO:0006446 82 53 0,000 0,2877012 0,30346737 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,2877012 0,30333439 ! activation of phospholipase C activity GO:0007202 103 54 0,000 0,29225021 0,30799562 GO:0010863|positive regulation of phospholipase C activity, ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,29225021 0,30786077 ! cell recognition GO:0008037 85 54 0,000 0,29225021 0,30772604 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,29225021 0,30759142 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,29225021 0,30745693 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,29225021 0,30732255 ! chloride transport GO:0006821 90 55 0,000 0,29677031 0,31193944 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,29677031 0,31180322 ! positive regulation of phospholipase activity GO:0010518 104 55 0,000 0,29677031 0,31166712 ! gastrulation GO:0007369 112 55 0,000 0,29677031 0,31153114 ! heart morphogenesis GO:0003007 97 55 0,000 0,29677031 0,31139528 ! nuclear export GO:0051168 97 55 0,000 0,29677031 0,31125953 ! sensory perception of smell GO:0007608 80 56 0,000 0,3012617 0,31583253 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,3012617 0,31569497 ! proton transport GO:0015992 94 56 0,000 0,3012617 0,31555753 ! regulation of bone remodeling GO:0046850 137 57 0,000 0,30572455 0,32009281 ! positive regulation of cell migration GO:0030335 126 57 0,000 0,30572455 0,31995357 ! regulation of phospholipase activity GO:0010517 106 57 0,000 0,30572455 0,31981446 ! hydrogen transport GO:0006818 97 58 0,000 0,31015904 0,32431233 ! regulation of tissue remodeling GO:0034103 140 58 0,000 0,31015904 0,32417144 ! regulation of endocytosis GO:0030100 91 58 0,000 0,31015904 0,32403068 ! positive regulation of lipase activity GO:0060193 108 58 0,000 0,31015904 0,32389004 ! positive regulation of secretion GO:0051047 95 59 0,000 0,31456536 0,32834892 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,31456536 0,32820653 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,31456536 0,32806426 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,31456536 0,32792212 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,31894368 0,33234235 ! regulation of heart contraction GO:0008016 110 60 0,000 0,31894368 0,33219848 ! kidney development GO:0001822 122 60 0,000 0,31894368 0,33205473 ! mesoderm development GO:0007498 119 61 0,000 0,32329417 0,33643849 ! tRNA processing GO:0008033 89 61 0,000 0,32329417 0,33629303 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,32329417 0,3361477 ! viral reproductive process GO:0022415 126 62 0,000 0,32761702 0,34049527 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,32761702 0,34034825 ! regulation of mitosis GO:0007088 105 63 0,000 0,3319124 0,34466173 GO:0051783|regulation of nuclear division, ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,3319124 0,34451304 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,3319124 0,34436448 ! steroid hormone receptor signaling pathway GO:0030518 129 63 0,000 0,3319124 0,34421605 ! cell redox homeostasis GO:0045454 102 64 0,000 0,33618047 0,34849212 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,33618047 0,34834204 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,33618047 0,34819209 ! positive regulation of cell motion GO:0051272 146 64 0,000 0,33618047 0,34804226 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,34042143 0,35228127 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,34042143 0,35212982 ! secondary metabolic process GO:0019748 116 66 0,000 0,34463543 0,35633555 ! cell projection assembly GO:0030031 120 66 0,000 0,34463543 0,35618249 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,34882264 0,36035521 ! negative regulation of protein kinase activity GO:0006469 130 67 0,000 0,34882264 0,36020055 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,34882264 0,36004602 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,34882264 0,35989163 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 0,000 0,34882264 0,35973737 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,34882264 0,35958324 ! activation of immune response GO:0002253 105 67 0,000 0,34882264 0,35942924 ! amino acid transport GO:0006865 125 68 0,000 0,35298324 0,36356065 ! negative regulation of kinase activity GO:0033673 131 68 0,000 0,35298324 0,36340508 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,35298324 0,36324965 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,35298324 0,36309435 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 0,000 0,35298324 0,36293918 ! viral reproduction GO:0016032 134 68 0,000 0,35298324 0,36278414 ! regulation of lipase activity GO:0060191 130 68 0,000 0,35298324 0,36262924 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,35298324 0,36247447 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,35298324 0,36231983 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,3571174 0,36640702 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,3571174 0,36625083 ! antigen processing and presentation GO:0019882 104 69 0,000 0,3571174 0,36609478 ! amine catabolic process GO:0009310 117 71 0,000 0,36530704 0,3743308 ! humoral immune response GO:0006959 109 71 0,000 0,36530704 0,37417145 ! regulation of immune effector process GO:0002697 137 71 0,000 0,36530704 0,37401222 ! acute inflammatory response GO:0002526 113 72 0,000 0,36936285 0,37800384 ! carbohydrate transport GO:0008643 110 72 0,000 0,36936285 0,37784312 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,36936285 0,37768254 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,36936285 0,3775221 ! negative regulation of transferase activity GO:0051348 140 72 0,000 0,36936285 0,37736179 ! learning or memory GO:0007611 147 73 0,000 0,37339288 0,38131718 ! fertilization GO:0009566 90 73 0,000 0,37339288 0,3811554 ! transition metal ion transport GO:0000041 126 74 0,000 0,3773973 0,38507968 ! exocytosis GO:0006887 133 74 0,000 0,3773973 0,38491645 ! cell-matrix adhesion GO:0007160 163 75 0,000 0,38137625 0,38880986 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,38137625 0,38864518 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,38137625 0,38848064 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,38532991 0,39234184 ! defense response to bacterium GO:0042742 89 76 0,000 0,38532991 0,39217587 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,38925843 0,39600667 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,38925843 0,3958393 ! positive regulation of lymphocyte activation GO:0051251 127 77 0,000 0,38925843 0,39567206 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,39704069 0,40341212 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,39704069 0,40324183 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 0,000 0,39704069 0,40307169 ! muscle cell differentiation GO:0042692 159 80 0,000 0,40089475 0,40681264 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,40089475 0,40664113 ! inorganic anion transport GO:0015698 138 80 0,000 0,40089475 0,40646977 ! response to hypoxia GO:0001666 171 81 0,000 0,4047243 0,41017972 ! digestion GO:0007586 112 81 0,000 0,4047243 0,41000702 ! cell-substrate adhesion GO:0031589 171 81 0,000 0,4047243 0,40983445 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,4047243 0,40966204 ! response to oxygen levels GO:0070482 176 83 0,000 0,4123105 0,41716529 ! regulation of ligase activity GO:0051340 142 84 0,000 0,41606745 0,42078953 ! nucleosome assembly GO:0006334 122 85 0,000 0,41980051 0,42438657 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,41980051 0,42420833 ! positive regulation of cell activation GO:0050867 145 85 0,000 0,41980051 0,42403024 GO:0002696|positive regulation of leukocyte activation, ! amine biosynthetic process GO:0009309 138 86 0,000 0,42350983 0,42759742 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,42350983 0,42741806 ! chromatin assembly GO:0031497 124 86 0,000 0,42350983 0,42723885 ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,42719556 0,43077641 ! cellular respiration GO:0045333 135 88 0,000 0,43085785 0,43428738 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,43085785 0,43410552 ! cellular defense response GO:0006968 114 89 0,000 0,43449684 0,4375887 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,43811269 0,44104566 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,44170553 0,44447658 ! regulation of defense response GO:0031347 149 92 0,000 0,44527552 0,44788165 ! nucleosome organization GO:0034728 138 92 0,000 0,44527552 0,44769449 ! vitamin metabolic process GO:0006766 139 92 0,000 0,44527552 0,44750748 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,4488228 0,4508842 GO:0010498|proteasomal protein catabolic process, ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,4488228 0,45069602 ! negative regulation of multicellular organismal process GO:0051241 166 93 0,000 0,4488228 0,45050799 ! female pregnancy GO:0007565 164 94 0,000 0,45234752 0,4538566 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,45584981 0,45717992 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,45932982 0,46047814 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! positive regulation of immune response GO:0050778 156 96 0,000 0,45932982 0,46028635 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,46278769 0,46355836 ! response to virus GO:0009615 160 98 0,000 0,46622355 0,46680561 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,46622355 0,46661143 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,46622355 0,46641741 GO:0016054|organic acid catabolic process, ! Golgi vesicle transport GO:0048193 207 99 0,000 0,46963756 0,46963756