pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6721-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! negative regulation of phosphorylation GO:0042326 52 24 5,000 6,457E-10 1,577E-06 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 5,000 1,097E-09 1,34E-06 GO:0045936|negative regulation of phosphate metabolic process, ! induction of apoptosis by intracellular signals GO:0008629 95 45 5,000 3,632E-08 2,958E-05 ! induction of positive chemotaxis GO:0050930 17 9 3,000 3,776E-08 2,306E-05 ! insulin receptor signaling pathway GO:0008286 66 27 4,000 9,376E-08 4,581E-05 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 4,000 1,138E-07 4,632E-05 ! regulation of positive chemotaxis GO:0050926 22 12 3,000 1,469E-07 5,127E-05 GO:0050927|positive regulation of positive chemotaxis, ! interphase of mitotic cell cycle GO:0051329 224 98 6,000 2,078E-07 6,345E-05 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 3,000 2,951E-07 8,011E-05 ! cellular response to insulin stimulus GO:0032869 85 38 4,000 5,616E-07 1,372E-04 ! single strand break repair GO:0000012 8 5 2,000 7,321E-07 1,626E-04 ! blood coagulation GO:0007596 151 79 5,000 1,102E-06 2,243E-04 GO:0050817|coagulation, ! apoptotic mitochondrial changes GO:0008637 42 20 3,000 1,401E-06 2,632E-04 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 4,000 1,492E-06 2,604E-04 ! response to insulin stimulus GO:0032868 98 47 4,000 1,664E-06 2,711E-04 ! hemostasis GO:0007599 165 85 5,000 1,698E-06 2,592E-04 ! apoptotic nuclear changes GO:0030262 34 22 3,000 2,101E-06 3,019E-04 ! positive regulation of locomotion GO:0040017 44 22 3,000 2,101E-06 2,851E-04 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! regulation of chemotaxis GO:0050920 45 23 3,000 2,535E-06 3,259E-04 ! N-terminal protein amino acid acetylation GO:0006474 14 7 2,000 2,547E-06 3,111E-04 ! fibrinolysis GO:0042730 11 7 2,000 2,547E-06 2,962E-04 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 2,000 2,547E-06 2,828E-04 ! regulation of behavior GO:0050795 48 25 3,000 3,597E-06 3,821E-04 ! ER overload response GO:0006983 13 8 2,000 4,062E-06 4,135E-04 ! regulation of T cell differentiation in the thymus GO:0033081 14 8 2,000 4,062E-06 3,969E-04 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 2,000 4,062E-06 3,817E-04 ! negative regulation of protein modification process GO:0031400 66 28 3,000 5,765E-06 5,217E-04 ! response to peptide hormone stimulus GO:0043434 129 64 4,000 7,81E-06 6,814E-04 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 2,000 8,65E-06 7,287E-04 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 2,000 8,65E-06 7,044E-04 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 2,000 8,65E-06 6,817E-04 ! negative regulation of protein kinase activity GO:0006469 144 69 4,000 1,132E-05 8,641E-04 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 4,000 1,132E-05 8,379E-04 ! peptide or protein amino-terminal blocking GO:0018409 22 11 2,000 1,186E-05 8,52E-04 ! chondrocyte differentiation GO:0002062 27 11 2,000 1,186E-05 8,276E-04 ! negative regulation of glucose import GO:0046325 18 11 2,000 1,186E-05 8,046E-04 GO:0010829|negative regulation of glucose transport, ! negative regulation of kinase activity GO:0033673 145 70 4,000 1,215E-05 8,021E-04 ! regulation of B cell proliferation GO:0030888 22 12 2,000 1,576E-05 1,013E-03 ! histone acetylation GO:0016573 27 12 2,000 1,576E-05 9,872E-04 ! peptidyl-lysine modification GO:0018205 21 12 2,000 1,576E-05 9,626E-04 ! negative regulation of mast cell proliferation GO:0070667 24 12 2,000 1,576E-05 9,391E-04 GO:0042130|negative regulation of T cell proliferation, ! negative regulation of transferase activity GO:0051348 155 74 4,000 1,595E-05 9,278E-04 ! regulation of protein stability GO:0031647 77 38 3,000 2,011E-05 1,143E-03 ! nucleus organization GO:0006997 73 40 3,000 2,474E-05 1,374E-03 ! positive regulation of phosphorylation GO:0042327 149 81 4,000 2,477E-05 1,345E-03 ! release of cytochrome c from mitochondria GO:0001836 31 14 2,000 2,591E-05 1,376E-03 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 4,000 2,789E-05 1,449E-03 GO:0045937|positive regulation of phosphate metabolic process, ! cellular response to hormone stimulus GO:0032870 182 85 4,000 3,129E-05 1,593E-03 ! N-terminal protein amino acid modification GO:0031365 30 15 2,000 3,229E-05 1,61E-03 ! regulation of the force of heart contraction GO:0002026 31 15 2,000 3,229E-05 1,578E-03 ! positive regulation of response to external stimulus GO:0032103 88 44 3,000 3,627E-05 1,737E-03 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 2,000 3,962E-05 1,862E-03 ! negative regulation of leukocyte proliferation GO:0070664 32 16 2,000 3,962E-05 1,826E-03 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! DNA fragmentation involved in apoptosis GO:0006309 27 17 2,000 4,796E-05 2,17E-03 ! neutrophil chemotaxis GO:0030593 29 17 2,000 4,796E-05 2,13E-03 ! negative regulation of blood coagulation GO:0030195 25 17 2,000 4,796E-05 2,092E-03 ! positive regulation of MAP kinase activity GO:0043406 174 93 4,000 4,825E-05 2,068E-03 ! positive regulation of cell cycle GO:0045787 96 48 3,000 5,131E-05 2,161E-03 ! negative regulation of multicellular organismal process GO:0051241 174 95 4,000 5,343E-05 2,212E-03 ! regulation of mast cell proliferation GO:0070666 89 49 3,000 5,569E-05 2,268E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 2,000 5,738E-05 2,298E-03 ! regulation of DNA metabolic process GO:0051052 188 97 4,000 5,903E-05 2,326E-03 ! activation of caspase activity GO:0006919 95 50 3,000 6,033E-05 2,34E-03 ! G1 phase of mitotic cell cycle GO:0000080 39 19 2,000 6,793E-05 2,593E-03 ! skeletal muscle tissue development GO:0007519 223 100 4,000 6,827E-05 2,566E-03 GO:0060538|skeletal muscle organ development, ! regulation of leukocyte proliferation GO:0070663 97 53 3,000 7,597E-05 2,812E-03 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! cartilage development GO:0051216 99 53 3,000 7,597E-05 2,77E-03 ! protein amino acid acetylation GO:0006473 41 20 2,000 7,967E-05 2,862E-03 ! regulation of glucose import GO:0046324 30 20 2,000 7,967E-05 2,821E-03 GO:0010827|regulation of glucose transport, ! negative regulation of T cell activation GO:0050868 41 20 2,000 7,967E-05 2,78E-03 ! negative regulation of coagulation GO:0050819 30 20 2,000 7,967E-05 2,741E-03 ! regulation of angiogenesis GO:0045765 125 54 3,000 8,177E-05 2,775E-03 ! response to UV GO:0009411 120 55 3,000 8,79E-05 2,942E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 2,000 9,266E-05 3,059E-03 ! cell structure disassembly during apoptosis GO:0006921 32 21 2,000 9,266E-05 3,018E-03 ! positive regulation of inflammatory response GO:0050729 41 21 2,000 9,266E-05 2,978E-03 ! regulation of DNA replication GO:0006275 105 56 3,000 9,435E-05 2,994E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 3,000 1,011E-04 3,168E-03 ! positive regulation of caspase activity GO:0043280 108 57 3,000 1,011E-04 3,128E-03 GO:0010952|positive regulation of peptidase activity, ! inactivation of MAPK activity GO:0000188 45 22 2,000 1,07E-04 3,266E-03 ! G1 phase GO:0051318 44 22 2,000 1,07E-04 3,226E-03 ! positive regulation of cell migration GO:0030335 137 58 3,000 1,083E-04 3,226E-03 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 2,000 1,397E-04 4,112E-03 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 2,000 1,397E-04 4,063E-03 ! platelet activation GO:0030168 41 24 2,000 1,397E-04 4,015E-03 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 2,000 1,583E-04 4,496E-03 ! protein tetramerization GO:0051262 57 25 2,000 1,583E-04 4,444E-03 ! protein amino acid autophosphorylation GO:0046777 157 64 3,000 1,59E-04 4,414E-03 ! positive regulation of cell motion GO:0051272 157 65 3,000 1,689E-04 4,636E-03 ! negative regulation of bone resorption GO:0045779 10 5 1,000 1,754E-04 4,762E-03 ! cell adhesion mediated by integrin GO:0033627 10 5 1,000 1,754E-04 4,71E-03 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 1,000 1,754E-04 4,659E-03 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 1,000 1,754E-04 4,609E-03 ! positive regulation of glycolysis GO:0045821 13 5 1,000 1,754E-04 4,56E-03 ! positive regulation of viral genome replication GO:0045070 9 5 1,000 1,754E-04 4,512E-03 ! negative regulation of survival gene product expression GO:0008634 9 5 1,000 1,754E-04 4,465E-03 ! microvillus organization GO:0032528 8 5 1,000 1,754E-04 4,419E-03 GO:0030033|microvillus assembly, ! muscle cell migration GO:0014812 8 5 1,000 1,754E-04 4,374E-03 ! regulation of phospholipase A2 activity GO:0032429 15 5 1,000 1,754E-04 4,329E-03 ! meiotic chromosome segregation GO:0045132 10 5 1,000 1,754E-04 4,286E-03 ! enteric nervous system development GO:0048484 8 5 1,000 1,754E-04 4,244E-03 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 1,000 1,754E-04 4,202E-03 ! protein insertion into membrane GO:0051205 17 5 1,000 1,754E-04 4,161E-03 ! stem cell division GO:0017145 11 5 1,000 1,754E-04 4,121E-03 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 1,000 1,754E-04 4,082E-03 ! myelination GO:0042552 50 26 2,000 1,784E-04 4,111E-03 ! response to endoplasmic reticulum stress GO:0034976 46 26 2,000 1,784E-04 4,072E-03 ! negative regulation of cell development GO:0010721 83 26 2,000 1,784E-04 4,034E-03 GO:0050768|negative regulation of neurogenesis, ! regulation of blood coagulation GO:0030193 46 26 2,000 1,784E-04 3,997E-03 ! positive regulation of nuclear division GO:0051785 41 26 2,000 1,784E-04 3,961E-03 GO:0045840|positive regulation of mitosis, ! negative regulation of cell growth GO:0030308 142 67 3,000 1,899E-04 4,18E-03 ! regulation of chromosome organization GO:0033044 49 27 2,000 2E-04 4,363E-03 ! negative regulation of lymphocyte activation GO:0051250 55 27 2,000 2E-04 4,324E-03 ! negative regulation of cell size GO:0045792 144 69 3,000 2,128E-04 4,561E-03 ! lung development GO:0030324 165 69 3,000 2,128E-04 4,521E-03 ! urogenital system development GO:0001655 149 69 3,000 2,128E-04 4,482E-03 ! regulation of fibroblast proliferation GO:0048145 56 28 2,000 2,233E-04 4,663E-03 ! protein amino acid acylation GO:0043543 59 28 2,000 2,233E-04 4,624E-03 ! ER-nuclear signaling pathway GO:0006984 52 29 2,000 2,483E-04 5,098E-03 ! respiratory tube development GO:0030323 171 72 3,000 2,508E-04 5,106E-03 ! regulation of smooth muscle cell differentiation GO:0051150 12 6 1,000 2,624E-04 5,299E-03 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 1,000 2,624E-04 5,255E-03 ! regulation of retroviral genome replication GO:0045091 8 6 1,000 2,624E-04 5,212E-03 ! regulation of immunoglobulin secretion GO:0051023 6 6 1,000 2,624E-04 5,17E-03 ! establishment of spindle localization GO:0051293 16 6 1,000 2,624E-04 5,129E-03 GO:0051653|spindle localization, ! negative regulation of gliogenesis GO:0014014 18 6 1,000 2,624E-04 5,088E-03 GO:0045686|negative regulation of glial cell differentiation, ! negative regulation of neuroblast proliferation GO:0007406 25 6 1,000 2,624E-04 5,048E-03 ! negative regulation of B cell activation GO:0050869 14 6 1,000 2,624E-04 5,009E-03 ! regulation of B cell activation GO:0050864 55 30 2,000 2,751E-04 5,209E-03 ! regulation of coagulation GO:0050818 52 30 2,000 2,751E-04 5,169E-03 ! regulation of caspase activity GO:0043281 136 74 3,000 2,787E-04 5,197E-03 ! respiratory system development GO:0060541 175 74 3,000 2,787E-04 5,158E-03 ! cell junction assembly GO:0034329 85 31 2,000 3,036E-04 5,577E-03 ! cellular response to extracellular stimulus GO:0031668 52 31 2,000 3,036E-04 5,535E-03 ! ensheathment of neurons GO:0007272 64 31 2,000 3,036E-04 5,494E-03 GO:0008366|axon ensheathment, ! negative regulation of leukocyte activation GO:0002695 60 31 2,000 3,036E-04 5,454E-03 ! regulation of endopeptidase activity GO:0052548 141 77 3,000 3,246E-04 5,788E-03 ! leukocyte chemotaxis GO:0030595 55 33 2,000 3,663E-04 6,484E-03 GO:0060326|cell chemotaxis, ! regulation of helicase activity GO:0051095 16 7 1,000 3,664E-04 6,44E-03 ! prostate gland development GO:0030850 14 7 1,000 3,664E-04 6,394E-03 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 3,664E-04 6,348E-03 ! mRNA stabilization GO:0048255 18 7 1,000 3,664E-04 6,303E-03 GO:0043489|RNA stabilization, ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 1,000 3,664E-04 6,259E-03 ! regulation of granule cell precursor proliferation GO:0021936 12 7 1,000 3,664E-04 6,216E-03 GO:0021940|positive regulation of granule cell precursor proliferation, ! attachment of GPI anchor to protein GO:0016255 16 7 1,000 3,664E-04 6,173E-03 ! male sex determination GO:0030238 15 7 1,000 3,664E-04 6,131E-03 ! wound healing, spreading of epidermal cells GO:0035313 16 7 1,000 3,664E-04 6,089E-03 ! G1 DNA damage checkpoint GO:0031571 20 7 1,000 3,664E-04 6,048E-03 ! B cell lineage commitment GO:0002326 21 7 1,000 3,664E-04 6,007E-03 ! T cell lineage commitment GO:0002360 16 7 1,000 3,664E-04 5,967E-03 ! response to hypoxia GO:0001666 178 81 3,000 3,939E-04 6,372E-03 ! response to hydrogen peroxide GO:0042542 56 34 2,000 4,005E-04 6,436E-03 ! negative regulation of MAP kinase activity GO:0043407 78 34 2,000 4,005E-04 6,394E-03 ! regulation of peptidase activity GO:0052547 150 82 3,000 4,127E-04 6,547E-03 ! response to oxygen levels GO:0070482 183 83 3,000 4,322E-04 6,812E-03 ! negative regulation of transport GO:0051051 164 85 3,000 4,731E-04 7,409E-03 ! negative regulation of growth GO:0045926 168 85 3,000 4,731E-04 7,362E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 1,000 4,872E-04 7,533E-03 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 1,000 4,872E-04 7,485E-03 ! negative regulation of muscle cell differentiation GO:0051148 17 8 1,000 4,872E-04 7,438E-03 ! T-helper 1 type immune response GO:0042088 12 8 1,000 4,872E-04 7,392E-03 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 4,872E-04 7,347E-03 ! positive regulation of endothelial cell migration GO:0010595 19 8 1,000 4,872E-04 7,302E-03 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 1,000 4,872E-04 7,257E-03 ! positive regulation of insulin secretion GO:0032024 17 8 1,000 4,872E-04 7,213E-03 ! cerebral cortex neuron differentiation GO:0021895 16 8 1,000 4,872E-04 7,17E-03 ! regulation of vascular permeability GO:0043114 12 8 1,000 4,872E-04 7,127E-03 ! DNA topological change GO:0006265 12 8 1,000 4,872E-04 7,084E-03 ! response to tumor cell GO:0002347 16 8 1,000 4,872E-04 7,042E-03 ! regulation of respiratory burst GO:0060263 12 8 1,000 4,872E-04 7,001E-03 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 1,000 4,872E-04 6,96E-03 ! cell junction organization GO:0034330 96 37 2,000 5,152E-04 7,317E-03 ! negative regulation of cell activation GO:0050866 69 37 2,000 5,152E-04 7,275E-03 ! mitochondrion organization GO:0007005 159 87 3,000 5,167E-04 7,255E-03 ! regulation of protein transport GO:0051223 165 87 3,000 5,167E-04 7,214E-03 GO:0070201|regulation of establishment of protein localization, ! tube morphogenesis GO:0035239 194 89 3,000 5,631E-04 7,817E-03 ! regulation of cell cycle process GO:0010564 161 90 3,000 5,874E-04 8,108E-03 ! carbohydrate homeostasis GO:0033500 59 39 2,000 6,022E-04 8,265E-03 GO:0042593|glucose homeostasis, ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 6,246E-04 8,525E-03 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 1,000 6,246E-04 8,477E-03 GO:0010469|regulation of receptor activity, ! regulation of glycolysis GO:0006110 20 9 1,000 6,246E-04 8,431E-03 ! middle ear morphogenesis GO:0042474 14 9 1,000 6,246E-04 8,384E-03 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 1,000 6,246E-04 8,339E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 1,000 6,246E-04 8,293E-03 ! retinol metabolic process GO:0042572 20 9 1,000 6,246E-04 8,248E-03 ! regulation of telomere maintenance GO:0032204 17 9 1,000 6,246E-04 8,204E-03 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 1,000 6,246E-04 8,16E-03 ! regulation of action potential in neuron GO:0019228 80 40 2,000 6,49E-04 8,434E-03 ! regulation of membrane potential GO:0042391 179 94 3,000 6,92E-04 8,945E-03 ! embryonic epithelial tube formation GO:0001838 85 41 2,000 6,981E-04 8,977E-03 ! T cell differentiation GO:0030217 93 42 2,000 7,495E-04 9,587E-03 ! regulation of T cell differentiation GO:0045580 78 42 2,000 7,495E-04 9,537E-03 ! regulation of protein secretion GO:0050708 77 42 2,000 7,495E-04 9,487E-03 ! regulation of protein localization GO:0032880 188 97 3,000 7,786E-04 9,805E-03 ! regulation of developmental growth GO:0048638 16 10 1,000 7,786E-04 9,755E-03 ! positive regulation of B cell proliferation GO:0030890 18 10 1,000 7,786E-04 9,705E-03 ! lung alveolus development GO:0048286 26 10 1,000 7,786E-04 9,656E-03 ! negative regulation of striated muscle development GO:0045843 26 10 1,000 7,786E-04 9,607E-03 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 1,000 7,786E-04 9,559E-03 ! motor axon guidance GO:0008045 22 10 1,000 7,786E-04 9,511E-03 ! regulation of bone resorption GO:0045124 25 10 1,000 7,786E-04 9,463E-03 ! protein heterooligomerization GO:0051291 17 10 1,000 7,786E-04 9,417E-03 ! regulation of gliogenesis GO:0014013 23 10 1,000 7,786E-04 9,37E-03 GO:0045685|regulation of glial cell differentiation, ! DNA ligation GO:0006266 18 10 1,000 7,786E-04 9,324E-03 ! musculoskeletal movement GO:0050881 16 10 1,000 7,786E-04 9,279E-03 GO:0050879|multicellular organismal movement, ! positive regulation of viral reproduction GO:0048524 19 10 1,000 7,786E-04 9,234E-03 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 1,000 7,786E-04 9,189E-03 GO:0043470|regulation of carbohydrate catabolic process, ! natural killer cell mediated immunity GO:0002228 19 10 1,000 7,786E-04 9,145E-03 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 1,000 7,786E-04 9,101E-03 ! regulation of T cell proliferation GO:0042129 80 43 2,000 8,033E-04 9,345E-03 ! neuron migration GO:0001764 85 43 2,000 8,033E-04 9,3E-03 ! response to reactive oxygen species GO:0000302 75 44 2,000 8,594E-04 9,903E-03 ! regulation of epithelial cell proliferation GO:0050678 122 45 2,000 9,179E-04 0,01052811 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 1,000 9,49E-04 0,01083373 ! negative regulation of muscle development GO:0048635 27 11 1,000 9,49E-04 0,01078334 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 1,000 9,49E-04 0,01073342 ! detection of mechanical stimulus GO:0050982 22 11 1,000 9,49E-04 0,01068396 ! blood vessel remodeling GO:0001974 30 11 1,000 9,49E-04 0,01063495 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 1,000 9,49E-04 0,01058639 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 23 11 1,000 9,49E-04 0,01053827 ! regulation of intracellular pH GO:0051453 21 11 1,000 9,49E-04 0,01049058 ! positive regulation of peptide secretion GO:0002793 24 11 1,000 9,49E-04 0,01044333 ! neuroblast proliferation GO:0007405 25 11 1,000 9,49E-04 0,0103965 ! positive regulation of leukocyte migration GO:0002687 28 11 1,000 9,49E-04 0,01035008 ! regulation of embryonic development GO:0045995 35 11 1,000 9,49E-04 0,01030408 ! regulation of gene-specific transcription GO:0032583 102 46 2,000 9,789E-04 0,01058211 ! leukocyte migration GO:0050900 75 46 2,000 9,789E-04 0,0105355 ! positive regulation of protein transport GO:0051222 80 46 2,000 9,789E-04 0,01048929 ! positive regulation of defense response GO:0031349 88 48 2,000 1,109E-03 0,01182614 ! cellular component disassembly GO:0022411 89 48 2,000 1,109E-03 0,01177472 ! regulation of inflammatory response GO:0050727 84 48 2,000 1,109E-03 0,01172375 ! positive regulation of cellular catabolic process GO:0031331 34 12 1,000 1,136E-03 0,01195863 ! virus-host interaction GO:0019048 30 12 1,000 1,136E-03 0,0119073 ! hippocampus development GO:0021766 29 12 1,000 1,136E-03 0,01185642 ! autonomic nervous system development GO:0048483 24 12 1,000 1,136E-03 0,01180596 ! regulation of leukocyte migration GO:0002685 29 12 1,000 1,136E-03 0,01175594 ! leukocyte mediated cytotoxicity GO:0001909 28 12 1,000 1,136E-03 0,01170634 ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 1,000 1,136E-03 0,01165715 ! localization within membrane GO:0051668 26 12 1,000 1,136E-03 0,01160838 ! regulation of lymphocyte differentiation GO:0045619 92 49 2,000 1,177E-03 0,01198306 ! regulation of action potential GO:0001508 102 50 2,000 1,249E-03 0,012656 ! induction of apoptosis by extracellular signals GO:0008624 99 50 2,000 1,249E-03 0,0126037 ! negative regulation of immune system process GO:0002683 101 51 2,000 1,322E-03 0,01329532 ! cartilage condensation GO:0001502 22 13 1,000 1,338E-03 0,01340068 ! endocrine pancreas development GO:0031018 25 13 1,000 1,338E-03 0,01334598 ! plasma membrane organization GO:0007009 27 13 1,000 1,338E-03 0,01329173 ! response to X-ray GO:0010165 28 13 1,000 1,338E-03 0,01323792 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 1,000 1,338E-03 0,01318454 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of monooxygenase activity GO:0032768 35 13 1,000 1,338E-03 0,01313159 ! regulation of mRNA stability GO:0043488 32 13 1,000 1,338E-03 0,01307906 ! morphogenesis of embryonic epithelium GO:0016331 106 52 2,000 1,399E-03 0,01361763 ! histone modification GO:0016570 104 52 2,000 1,399E-03 0,01356359 ! retina development in camera-type eye GO:0060041 28 14 1,000 1,557E-03 0,01503627 ! cell-cell junction assembly GO:0007043 32 14 1,000 1,557E-03 0,01497707 ! regulation of cellular pH GO:0030641 27 14 1,000 1,557E-03 0,01491833 ! response to gamma radiation GO:0010332 30 14 1,000 1,557E-03 0,01486006 ! regulation of RNA stability GO:0043487 33 14 1,000 1,557E-03 0,01480224 ! regulation of muscle contraction GO:0006937 94 54 2,000 1,561E-03 0,01477786 ! covalent chromatin modification GO:0016569 115 54 2,000 1,561E-03 0,01472081 ! epithelial tube morphogenesis GO:0060562 114 54 2,000 1,561E-03 0,01466419 ! negative regulation of bone remodeling GO:0046851 34 15 1,000 1,792E-03 0,01677125 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 1,000 1,792E-03 0,01670724 ! G1/S transition checkpoint GO:0031575 37 15 1,000 1,792E-03 0,01664371 ! cell killing GO:0001906 32 15 1,000 1,792E-03 0,01658067 ! heart morphogenesis GO:0003007 105 57 2,000 1,824E-03 0,01681629 ! aging GO:0007568 112 58 2,000 1,918E-03 0,01761263 ! positive regulation of organelle organization GO:0010638 108 58 2,000 1,918E-03 0,01754666 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 2,042E-03 0,01861491 ! heterophilic cell adhesion GO:0007157 43 16 1,000 2,042E-03 0,01854571 ! negative regulation of tissue remodeling GO:0034104 37 16 1,000 2,042E-03 0,01847702 ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 2,042E-03 0,01840884 ! DNA catabolic process GO:0006308 94 60 2,000 2,114E-03 0,01898485 ! regulation of heart contraction GO:0008016 123 61 2,000 2,216E-03 0,01983264 ! negative regulation of response to stimulus GO:0048585 106 61 2,000 2,216E-03 0,01976026 ! negative regulation of cell cycle process GO:0010948 35 17 1,000 2,308E-03 0,02050307 ! embryonic forelimb morphogenesis GO:0035115 31 17 1,000 2,308E-03 0,02042878 ! regulation of muscle cell differentiation GO:0051147 36 17 1,000 2,308E-03 0,02035503 ! activation of MAPKK activity GO:0000186 43 17 1,000 2,308E-03 0,02028181 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 1,000 2,308E-03 0,02020912 ! regulation of survival gene product expression GO:0045884 38 17 1,000 2,308E-03 0,02013694 ! cardiac muscle tissue development GO:0048738 34 17 1,000 2,308E-03 0,02006528 ! genitalia development GO:0048806 32 17 1,000 2,308E-03 0,01999413 ! negative regulation of homeostatic process GO:0032845 36 17 1,000 2,308E-03 0,01992348 ! regulation of homeostatic process GO:0032844 148 62 2,000 2,322E-03 0,01997239 ! regulation of mitosis GO:0007088 112 63 2,000 2,43E-03 0,02083333 GO:0051783|regulation of nuclear division, ! skeletal system morphogenesis GO:0048705 118 63 2,000 2,43E-03 0,02076048 ! integrin-mediated signaling pathway GO:0007229 160 64 2,000 2,542E-03 0,02163903 ! limbic system development GO:0021761 40 18 1,000 2,589E-03 0,02196394 ! regulation of viral genome replication GO:0045069 30 18 1,000 2,589E-03 0,02188794 ! response to retinoic acid GO:0032526 31 18 1,000 2,589E-03 0,02181247 ! cell-substrate junction assembly GO:0007044 56 18 1,000 2,589E-03 0,02173751 ! neural crest cell migration GO:0001755 41 18 1,000 2,589E-03 0,02166307 ! regulation of immunoglobulin production GO:0002637 49 18 1,000 2,589E-03 0,02158913 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 1,000 2,589E-03 0,0215157 ! neuron maturation GO:0042551 46 19 1,000 2,886E-03 0,02389926 ! positive regulation of hormone secretion GO:0046887 35 19 1,000 2,886E-03 0,02381852 ! memory GO:0007613 34 19 1,000 2,886E-03 0,02373832 ! response to vitamin A GO:0033189 32 19 1,000 2,886E-03 0,02365867 ! neuromuscular junction development GO:0007528 43 19 1,000 2,886E-03 0,02357954 ! regulation of endothelial cell migration GO:0010594 45 19 1,000 2,886E-03 0,02350094 ! vitamin transport GO:0051180 31 19 1,000 2,886E-03 0,02342286 ! embryonic organ morphogenesis GO:0048562 34 19 1,000 2,886E-03 0,02334531 ! activation of MAPK activity GO:0000187 124 67 2,000 2,896E-03 0,02335054 ! chromosome segregation GO:0007059 127 67 2,000 2,896E-03 0,02327373 ! single fertilization GO:0007338 83 69 2,000 3,148E-03 0,02521593 ! phosphoinositide phosphorylation GO:0046854 40 20 1,000 3,198E-03 0,02552948 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 1,000 3,198E-03 0,02544632 ! response to vitamin GO:0033273 36 20 1,000 3,198E-03 0,02536371 ! regulation of carbohydrate metabolic process GO:0006109 37 20 1,000 3,198E-03 0,02528162 GO:0010675|regulation of cellular carbohydrate metabolic process, ! forelimb morphogenesis GO:0035136 35 20 1,000 3,198E-03 0,02520007 ! response to alkaloid GO:0043279 38 20 1,000 3,198E-03 0,02511904 ! retinoid metabolic process GO:0001523 34 20 1,000 3,198E-03 0,02503853 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 40 20 1,000 3,198E-03 0,02495854 ! peptidyl-serine phosphorylation GO:0018105 44 20 1,000 3,198E-03 0,02487905 ! cell-cell junction organization GO:0045216 43 20 1,000 3,198E-03 0,02480007 ! cell cycle checkpoint GO:0000075 145 71 2,000 3,413E-03 0,02638736 ! lipid phosphorylation GO:0046834 43 21 1,000 3,525E-03 0,0271625 ! plasma membrane fusion GO:0045026 33 21 1,000 3,525E-03 0,02707708 ! negative regulation of angiogenesis GO:0016525 49 21 1,000 3,525E-03 0,0269922 ! vitamin A metabolic process GO:0006776 35 21 1,000 3,525E-03 0,02690785 ! camera-type eye morphogenesis GO:0048593 47 21 1,000 3,525E-03 0,02682403 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 1,000 3,525E-03 0,02674072 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 2,000 3,836E-03 0,02901133 ! hindlimb morphogenesis GO:0035137 47 22 1,000 3,866E-03 0,02915257 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 1,000 3,866E-03 0,02906287 ! cellular response to starvation GO:0009267 37 22 1,000 3,866E-03 0,02897372 ! ureteric bud development GO:0001657 50 22 1,000 3,866E-03 0,02888512 ! cell aging GO:0007569 48 22 1,000 3,866E-03 0,02879706 ! positive regulation of intracellular transport GO:0032388 42 22 1,000 3,866E-03 0,02870953 ! peptidyl-serine modification GO:0018209 50 22 1,000 3,866E-03 0,02862253 ! positive regulation of B cell activation GO:0050871 42 22 1,000 3,866E-03 0,02853606 ! terpenoid metabolic process GO:0006721 40 22 1,000 3,866E-03 0,0284501 ! gut development GO:0048565 44 22 1,000 3,866E-03 0,02836467 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 1,000 3,866E-03 0,02827974 ! regulation of transcription factor activity GO:0051090 137 75 2,000 3,983E-03 0,02904846 GO:0090046|regulation of transcription regulator activity, ! reproductive structure development GO:0048608 131 75 2,000 3,983E-03 0,028962 ! phosphoinositide-mediated signaling GO:0048015 141 75 2,000 3,983E-03 0,02887606 ! learning or memory GO:0007611 161 76 2,000 4,134E-03 0,02988211 ! lymphocyte differentiation GO:0030098 193 76 2,000 4,134E-03 0,02979396 ! positive regulation of DNA replication GO:0045740 44 23 1,000 4,223E-03 0,03034256 ! gluconeogenesis GO:0006094 38 23 1,000 4,223E-03 0,03025358 ! regulation of cell-matrix adhesion GO:0001952 81 23 1,000 4,223E-03 0,03016512 GO:0010810|regulation of cell-substrate adhesion, ! activation of pro-apoptotic gene products GO:0008633 51 23 1,000 4,223E-03 0,03007717 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 1,000 4,223E-03 0,02998974 ! phosphoinositide metabolic process GO:0030384 146 77 2,000 4,289E-03 0,03036948 ! regulation of catabolic process GO:0009894 173 77 2,000 4,289E-03 0,03028171 ! fertilization GO:0009566 99 78 2,000 4,447E-03 0,03130618 ! positive regulation of cell adhesion GO:0045785 61 24 1,000 4,594E-03 0,03225087 ! regulation of cellular catabolic process GO:0031329 55 24 1,000 4,594E-03 0,03215846 ! sex determination GO:0007530 48 24 1,000 4,594E-03 0,03206658 ! regulation of viral reproduction GO:0050792 41 24 1,000 4,594E-03 0,03197523 ! pallium development GO:0021543 56 24 1,000 4,594E-03 0,03188439 ! regulation of oxidoreductase activity GO:0051341 48 24 1,000 4,594E-03 0,03179406 ! protein oligomerization GO:0051259 149 79 2,000 4,608E-03 0,03180094 ! protein import into nucleus, translocation GO:0000060 51 25 1,000 4,98E-03 0,03426936 ! positive regulation of fibroblast proliferation GO:0048146 48 25 1,000 4,98E-03 0,0341731 ! leukocyte adhesion GO:0007159 55 25 1,000 4,98E-03 0,03407738 ! vasculogenesis GO:0001570 49 25 1,000 4,98E-03 0,03398219 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 1,000 4,98E-03 0,03388753 ! negative regulation of DNA replication GO:0008156 45 25 1,000 4,98E-03 0,0337934 ! chromosome condensation GO:0030261 48 25 1,000 4,98E-03 0,03369979 ! regulation of insulin secretion GO:0050796 42 25 1,000 4,98E-03 0,03360669 ! interaction with host GO:0051701 66 25 1,000 4,98E-03 0,03351411 ! positive regulation of protein secretion GO:0050714 41 25 1,000 4,98E-03 0,03342204 ! response to drug GO:0042493 149 83 2,000 5,289E-03 0,03539956 ! pyruvate metabolic process GO:0006090 43 26 1,000 5,38E-03 0,03591015 ! digestive system process GO:0022600 49 26 1,000 5,38E-03 0,0358123 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 1,000 5,38E-03 0,03571499 ! neural crest cell development GO:0014032 59 26 1,000 5,38E-03 0,0356182 GO:0014033|neural crest cell differentiation, ! neural tube closure GO:0001843 58 26 1,000 5,38E-03 0,03552193 GO:0060606|tube closure, ! T cell activation GO:0042110 189 84 2,000 5,468E-03 0,03600663 ! tube lumen formation GO:0035148 59 27 1,000 5,794E-03 0,03805234 ! regulation of endothelial cell proliferation GO:0001936 60 27 1,000 5,794E-03 0,03795033 ! mitochondrial membrane organization GO:0007006 60 27 1,000 5,794E-03 0,03784885 ! response to starvation GO:0042594 47 27 1,000 5,794E-03 0,03774792 ! cellular response to nutrient levels GO:0031669 45 27 1,000 5,794E-03 0,03764753 ! fat-soluble vitamin metabolic process GO:0006775 42 27 1,000 5,794E-03 0,03754767 ! base-excision repair GO:0006284 41 28 1,000 6,223E-03 0,04021795 ! peptidyl-tyrosine modification GO:0018212 57 28 1,000 6,223E-03 0,04011183 ! glutathione metabolic process GO:0006749 42 28 1,000 6,223E-03 0,04000627 ! regulation of DNA binding GO:0051101 167 89 2,000 6,418E-03 0,0411541 ! positive regulation of protein modification process GO:0031401 156 90 2,000 6,619E-03 0,04233222 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 1,000 6,665E-03 0,04251578 ! cellular iron ion homeostasis GO:0006879 57 29 1,000 6,665E-03 0,04240507 ! primary neural tube formation GO:0014020 61 29 1,000 6,665E-03 0,04229492 ! regulation of peptide secretion GO:0002791 52 29 1,000 6,665E-03 0,04218535 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 1,000 6,665E-03 0,04207635 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 1,000 6,665E-03 0,0419679 ! somitogenesis GO:0001756 52 29 1,000 6,665E-03 0,04186001 ! negative regulation of neuron differentiation GO:0045665 46 29 1,000 6,665E-03 0,04175268 ! ossification GO:0001503 205 91 2,000 6,824E-03 0,04263729 ! gland development GO:0048732 220 91 2,000 6,824E-03 0,04252853 ! bone development GO:0060348 206 92 2,000 7,033E-03 0,04371648 ! regulation of cell adhesion GO:0030155 241 92 2,000 7,033E-03 0,04360553 ! neurotransmitter secretion GO:0007269 55 30 1,000 7,122E-03 0,04404723 ! negative regulation of transcription regulator activity GO:0090048 57 30 1,000 7,122E-03 0,043936 GO:0043433|negative regulation of transcription factor activity, ! tissue homeostasis GO:0001894 50 30 1,000 7,122E-03 0,04382533 GO:0048871|multicellular organismal homeostasis, ! iron ion homeostasis GO:0055072 60 31 1,000 7,592E-03 0,04660153 ! eye morphogenesis GO:0048592 65 31 1,000 7,592E-03 0,04648473 ! regulation of defense response GO:0031347 171 95 2,000 7,681E-03 0,04690971 ! sex differentiation GO:0007548 171 96 2,000 7,904E-03 0,04815499 ! regulation of T cell activation GO:0050863 175 96 2,000 7,904E-03 0,0480352 ! spindle organization GO:0007051 50 32 1,000 8,076E-03 0,04895659 ! metanephros development GO:0001656 81 32 1,000 8,076E-03 0,04883541 ! response to mechanical stimulus GO:0009612 60 32 1,000 8,076E-03 0,04871483 ! hexose biosynthetic process GO:0019319 53 32 1,000 8,076E-03 0,04859484 ! peripheral nervous system development GO:0007422 68 32 1,000 8,076E-03 0,04847545 ! positive regulation of catabolic process GO:0009896 72 32 1,000 8,076E-03 0,04835663 ! leukocyte differentiation GO:0002521 232 98 2,000 8,363E-03 0,04995268 ! forebrain development GO:0030900 210 98 2,000 8,363E-03 0,04983085 ! regulation of pH GO:0006885 56 33 1,000 8,573E-03 0,05096022 ! positive regulation of gene-specific transcription GO:0043193 70 33 1,000 8,573E-03 0,05083653 ! response to ionizing radiation GO:0010212 74 33 1,000 8,573E-03 0,05071344 ! GPI anchor biosynthetic process GO:0006506 58 34 1,000 9,084E-03 0,05360519 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 1,000 9,084E-03 0,05347602 ! DNA damage checkpoint GO:0000077 78 35 1,000 9,608E-03 0,05642524 ! negative regulation of secretion GO:0051048 68 35 1,000 9,608E-03 0,05628993 ! negative regulation of DNA metabolic process GO:0051053 65 35 1,000 9,608E-03 0,05615526 ! GPI anchor metabolic process GO:0006505 61 35 1,000 9,608E-03 0,05602124 ! regulation of striated muscle tissue development GO:0016202 81 35 1,000 9,608E-03 0,05588785 ! telencephalon development GO:0021537 81 35 1,000 9,608E-03 0,0557551 ! calcium-mediated signaling GO:0019722 67 35 1,000 9,608E-03 0,05562298 ! regulation of muscle development GO:0048634 82 36 1,000 0,01014548 0,05859436 ! mitotic sister chromatid segregation GO:0000070 63 36 1,000 0,01014548 0,05845617 ! negative regulation of DNA binding GO:0043392 67 36 1,000 0,01014548 0,05831862 ! regulation of proteolysis GO:0030162 77 36 1,000 0,01014548 0,05818173 ! negative regulation of hydrolase activity GO:0051346 66 36 1,000 0,01014548 0,05804547 ! embryonic organ development GO:0048568 67 36 1,000 0,01014548 0,05790985 ! monosaccharide biosynthetic process GO:0046364 57 36 1,000 0,01014548 0,05777486 ! regulation of smooth muscle cell proliferation GO:0048660 64 37 1,000 0,01069579 0,06076699 ! negative regulation of cell adhesion GO:0007162 94 37 1,000 0,01069579 0,060626 ! sister chromatid segregation GO:0000819 65 37 1,000 0,01069579 0,06048566 ! tissue remodeling GO:0048771 78 37 1,000 0,01069579 0,06034597 ! androgen receptor signaling pathway GO:0030521 81 37 1,000 0,01069579 0,06020692 ! positive regulation of DNA metabolic process GO:0051054 77 38 1,000 0,01125902 0,06323168 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 1,000 0,01125902 0,06308665 ! meiosis I GO:0007127 74 38 1,000 0,01125902 0,06294229 ! DNA integrity checkpoint GO:0031570 82 38 1,000 0,01125902 0,06279858 ! glycogen metabolic process GO:0005977 63 38 1,000 0,01125902 0,06265553 ! neural tube formation GO:0001841 79 38 1,000 0,01125902 0,06251313 ! negative regulation of binding GO:0051100 71 39 1,000 0,01183506 0,06556247 ! mitotic cell cycle checkpoint GO:0007093 76 39 1,000 0,01183506 0,06541414 ! isoprenoid metabolic process GO:0006720 70 39 1,000 0,01183506 0,06526648 ! positive regulation of leukocyte proliferation GO:0070665 70 39 1,000 0,01183506 0,06511949 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! glucan metabolic process GO:0044042 64 39 1,000 0,01183506 0,06497315 GO:0006073|cellular glucan metabolic process, ! mammary gland development GO:0030879 93 40 1,000 0,0124238 0,06805232 ! development of primary female sexual characteristics GO:0046545 80 40 1,000 0,0124238 0,06790008 GO:0046660|female sex differentiation, ! phosphoinositide biosynthetic process GO:0046489 77 41 1,000 0,01302511 0,07102757 ! regulation of hormone secretion GO:0046883 69 41 1,000 0,01302511 0,07086938 ! mesenchymal cell development GO:0014031 94 41 1,000 0,01302511 0,07071189 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! monovalent inorganic cation homeostasis GO:0055067 72 41 1,000 0,01302511 0,0705551 ! ear morphogenesis GO:0042471 64 42 1,000 0,01363889 0,07371641 ! alcohol biosynthetic process GO:0046165 65 42 1,000 0,01363889 0,07355368 ! regulation of intracellular protein transport GO:0033157 86 42 1,000 0,01363889 0,07339166 ! cytokinesis GO:0000910 84 42 1,000 0,01363889 0,07323036 ! positive regulation of transcription factor activity GO:0051091 71 43 1,000 0,01426502 0,07642423 GO:0090047|positive regulation of transcription regulator activity, ! epithelial cell differentiation GO:0030855 83 43 1,000 0,01426502 0,076257 ! segmentation GO:0035282 78 43 1,000 0,01426502 0,0760905 ! energy reserve metabolic process GO:0006112 76 44 1,000 0,01490339 0,07932238 ! double-strand break repair GO:0006302 85 44 1,000 0,01490339 0,07914994 ! branching morphogenesis of a tube GO:0048754 102 45 1,000 0,01555387 0,0824254 ! B cell differentiation GO:0030183 124 45 1,000 0,01555387 0,08224699 ! developmental growth GO:0048589 88 45 1,000 0,01555387 0,08206935 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 1,000 0,01621637 0,08538058 ! pigmentation GO:0043473 103 46 1,000 0,01621637 0,08519697 ! cell growth GO:0016049 90 46 1,000 0,01621637 0,08501414 ! neural tube development GO:0021915 91 47 1,000 0,01689076 0,08836004 ! mitochondrial transport GO:0006839 94 48 1,000 0,01757695 0,09175317 ! positive regulation of DNA binding GO:0043388 83 48 1,000 0,01757695 0,09155754 ! vascular process in circulatory system GO:0003018 85 48 1,000 0,01757695 0,09136273 ! detection of stimulus involved in sensory perception GO:0050906 75 49 1,000 0,01827481 0,09478845 ! endocrine system development GO:0035270 109 50 1,000 0,01898424 0,09825952 ! peptide metabolic process GO:0006518 80 51 1,000 0,01970513 0,10177511 ! detection of abiotic stimulus GO:0009582 80 51 1,000 0,01970513 0,10156039 ! positive regulation of binding GO:0051099 88 52 1,000 0,02043737 0,10511261 ! morphogenesis of a branching structure GO:0001763 116 52 1,000 0,02043737 0,10489179 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 0,02092443 0,10716642 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 0,02092443 0,10694223 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 0,02092443 0,10671897 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,02092443 0,10649663 ! positive regulation of helicase activity GO:0051096 12 5 0,000 0,02092443 0,10627523 ! neuron fate determination GO:0048664 7 5 0,000 0,02092443 0,10605474 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02092443 0,10583517 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 0,02092443 0,1056165 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 0,02092443 0,10539873 ! polyol transport GO:0015791 12 5 0,000 0,02092443 0,10518186 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,02092443 0,10496588 ! response to superoxide GO:0000303 10 5 0,000 0,02092443 0,10475079 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 0,02092443 0,10453657 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 0,02092443 0,10432323 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,02092443 0,10411076 ! female meiosis GO:0007143 10 5 0,000 0,02092443 0,10389916 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,02092443 0,10368841 ! hypothalamus development GO:0021854 9 5 0,000 0,02092443 0,10347851 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 0,02092443 0,10326946 ! cobalt ion transport GO:0006824 11 5 0,000 0,02092443 0,10306126 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 0,02092443 0,10285389 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 0,02092443 0,10264736 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,02092443 0,10244165 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,02092443 0,10223677 ! embryonic camera-type eye development GO:0031076 12 5 0,000 0,02092443 0,1020327 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,02092443 0,10182945 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02092443 0,10162701 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 0,02092443 0,10142537 ! transposition GO:0032196 9 5 0,000 0,02092443 0,10122452 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 0,02092443 0,10102448 ! negative chemotaxis GO:0050919 16 5 0,000 0,02092443 0,10082522 ! positive regulation of histone modification GO:0031058 6 5 0,000 0,02092443 0,10062674 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,02092443 0,10042905 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 0,02092443 0,10023213 ! behavioral response to pain GO:0048266 10 5 0,000 0,02092443 0,10003598 ! clathrin coat assembly GO:0048268 15 5 0,000 0,02092443 0,0998406 ! Notch receptor processing GO:0007220 11 5 0,000 0,02092443 0,09964597 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02092443 0,09945211 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 0,02092443 0,099259 ! micturition GO:0060073 9 5 0,000 0,02092443 0,09906664 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,02092443 0,09887502 ! copulation GO:0007620 9 5 0,000 0,02092443 0,09868414 ! glial cell fate commitment GO:0021781 14 5 0,000 0,02092443 0,098494 ! protein maturation by protein folding GO:0022417 14 5 0,000 0,02092443 0,09830459 ! bioluminescence GO:0008218 9 5 0,000 0,02092443 0,0981159 ! spermidine metabolic process GO:0008216 7 5 0,000 0,02092443 0,09792794 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,02092443 0,0977407 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,02092443 0,09755417 ! apoptotic cell clearance GO:0043277 23 5 0,000 0,02092443 0,09736835 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,02092443 0,09718324 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 0,02092443 0,09699883 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,02092443 0,09681512 ! grooming behavior GO:0007625 6 5 0,000 0,02092443 0,09663211 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 0,02092443 0,09644978 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,02092443 0,09626814 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 0,02092443 0,09608719 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02092443 0,09590691 ! response to protozoan GO:0001562 13 5 0,000 0,02092443 0,09572731 ! lymph vessel development GO:0001945 10 5 0,000 0,02092443 0,09554838 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 0,02092443 0,09537012 ! endochondral ossification GO:0001958 17 5 0,000 0,02092443 0,09519252 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,02092443 0,09501558 ! parathyroid gland development GO:0060017 14 5 0,000 0,02092443 0,0948393 ! anagen GO:0042640 7 5 0,000 0,02092443 0,09466368 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,02092443 0,0944887 ! cytokine secretion GO:0050663 15 5 0,000 0,02092443 0,09431436 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 0,02092443 0,09414067 ! ceramide catabolic process GO:0046514 7 5 0,000 0,02092443 0,09396762 ! skeletal myofibril assembly GO:0014866 12 5 0,000 0,02092443 0,0937952 ! smooth muscle tissue development GO:0048745 32 5 0,000 0,02092443 0,09362342 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,02092443 0,09345226 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,02092443 0,09328172 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,02092443 0,09311181 ! cardiac muscle fiber development GO:0048739 12 5 0,000 0,02092443 0,09294252 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,02092443 0,09277384 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,02092443 0,09260577 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 0,02092443 0,09243831 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,02092443 0,09227145 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 0,02092443 0,0921052 ! glycine biosynthetic process GO:0006545 7 5 0,000 0,02092443 0,09193954 ! valine metabolic process GO:0006573 12 5 0,000 0,02092443 0,09177448 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 0,02092443 0,09161001 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 0,02092443 0,09144613 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 0,02092443 0,09128283 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 0,02092443 0,09112012 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 0,02092443 0,09095798 ! polyol catabolic process GO:0046174 9 5 0,000 0,02092443 0,09079642 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 0,02092443 0,09063543 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 0,02092443 0,09047502 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 0,02092443 0,09031517 ! mitochondrial fission GO:0000266 8 5 0,000 0,02092443 0,09015588 ! sister chromatid cohesion GO:0007062 15 5 0,000 0,02092443 0,08999716 ! response to tumor necrosis factor GO:0034612 10 5 0,000 0,02092443 0,08983899 ! mRNA transcription GO:0009299 10 5 0,000 0,02092443 0,08968138 ! nerve growth factor processing GO:0032455 9 5 0,000 0,02092443 0,08952432 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 0,02092443 0,08936781 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 0,02092443 0,08921184 ! anaerobic glycolysis GO:0019642 6 5 0,000 0,02092443 0,08905642 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,02092443 0,08890154 ! monocyte activation GO:0042117 10 5 0,000 0,02092443 0,0887472 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,02092443 0,08859339 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,02092443 0,08844011 ! response to food GO:0032094 6 5 0,000 0,02092443 0,08828737 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,02092443 0,08813515 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,02092443 0,08798345 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 0,02092443 0,08783228 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02092443 0,08768162 ! forebrain neuron development GO:0021884 13 5 0,000 0,02092443 0,08753148 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,02092443 0,08738185 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 0,02092443 0,08723274 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 0,02092443 0,08708413 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,02092443 0,08693603 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02092443 0,08678843 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 0,02092443 0,08664133 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,02092443 0,08649473 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 0,02092443 0,08634862 ! lipid glycosylation GO:0030259 7 5 0,000 0,02092443 0,08620301 ! nucleobase transport GO:0015851 6 5 0,000 0,02092443 0,08605789 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02092443 0,08591325 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 0,02092443 0,0857691 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 0,02092443 0,08562544 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 0,02092443 0,08548225 ! basic amino acid transport GO:0015802 12 5 0,000 0,02092443 0,08533954 ! cellular glucose homeostasis GO:0001678 6 5 0,000 0,02092443 0,08519731 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 0,02092443 0,08505555 ! actin nucleation GO:0045010 11 5 0,000 0,02092443 0,08491426 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,02092443 0,08477344 ! depurination GO:0045007 5 5 0,000 0,02092443 0,08463309 ! depyrimidination GO:0045008 10 5 0,000 0,02092443 0,0844932 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,02092443 0,08435377 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02092443 0,0842148 ! G2/M transition checkpoint GO:0031576 8 5 0,000 0,02092443 0,08407629 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,02092443 0,08393823 ! zinc ion homeostasis GO:0055069 9 5 0,000 0,02092443 0,08380063 GO:0006882|cellular zinc ion homeostasis, ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 0,02092443 0,08366348 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02092443 0,08352677 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,02092443 0,08339051 ! activated T cell proliferation GO:0050798 16 5 0,000 0,02092443 0,0832547 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,02092443 0,08311932 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 0,02092443 0,08298439 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,02092443 0,08284989 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02092443 0,08271583 ! gamma-delta T cell activation GO:0046629 6 5 0,000 0,02092443 0,0825822 ! response to arsenic GO:0046685 11 5 0,000 0,02092443 0,08244901 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 0,02092443 0,08231624 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,02092443 0,0821839 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 0,02092443 0,08205198 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 0,02092443 0,08192049 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 0,02092443 0,08178942 ! response to mercury ion GO:0046689 8 5 0,000 0,02092443 0,08165876 ! response to cadmium ion GO:0046686 7 5 0,000 0,02092443 0,08152852 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 0,02092443 0,0813987 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 0,02092443 0,08126929 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 0,02092443 0,08114029 ! bile acid biosynthetic process GO:0006699 7 5 0,000 0,02092443 0,0810117 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 0,02092443 0,08088352 ! ganglioside catabolic process GO:0006689 12 5 0,000 0,02092443 0,08075574 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,02092443 0,08062837 ! decidualization GO:0046697 11 5 0,000 0,02092443 0,08050139 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 0,02092443 0,08037482 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 0,02092443 0,08024864 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 0,02092443 0,08012286 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 0,02092443 0,07999747 ! embryonic cleavage GO:0040016 6 5 0,000 0,02092443 0,07987248 ! peroxisome fission GO:0016559 5 5 0,000 0,02092443 0,07974787 ! histone demethylation GO:0016577 13 5 0,000 0,02092443 0,07962365 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 0,02092443 0,07949982 ! mitotic recombination GO:0006312 9 5 0,000 0,02092443 0,07937637 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 0,02092443 0,07925331 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,02092443 0,07913063 ! metaphase plate congression GO:0051310 7 5 0,000 0,02092443 0,07900832 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02092443 0,0788864 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,02092443 0,07876485 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 0,02092443 0,07864367 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 0,02092443 0,07852286 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 0,02092443 0,07840243 ! muscle cell proliferation GO:0033002 12 5 0,000 0,02092443 0,07828237 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,02092443 0,07816267 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 0,02092443 0,07804334 ! B cell homeostasis GO:0001782 13 5 0,000 0,02092443 0,07792437 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 0,02092443 0,07780576 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,02092443 0,07768751 ! metaphase GO:0051323 11 5 0,000 0,02092443 0,07756963 ! melatonin biosynthetic process GO:0030187 7 5 0,000 0,02092443 0,0774521 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 0,02092443 0,07733492 ! cellular response to nutrient GO:0031670 8 5 0,000 0,02092443 0,0772181 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,02092443 0,07710164 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 0,02092443 0,07698552 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 0,02092443 0,07686975 ! regulation of hair follicle development GO:0051797 10 5 0,000 0,02092443 0,07675433 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 0,02092443 0,07663926 ! response to redox state GO:0051775 6 5 0,000 0,02092443 0,07652453 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 0,02092443 0,07641014 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 0,02092443 0,0762961 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,02092443 0,07618239 ! brown fat cell differentiation GO:0050873 7 5 0,000 0,02092443 0,07606902 ! regulation of telomerase activity GO:0051972 7 5 0,000 0,02092443 0,075956 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02092443 0,0758433 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 0,02092443 0,07573094 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02092443 0,07561891 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 0,02092443 0,07550722 ! striatum development GO:0021756 14 5 0,000 0,02092443 0,07539585 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 0,02092443 0,07528481 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,02092443 0,0751741 ! glial cell migration GO:0008347 10 5 0,000 0,02092443 0,07506371 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,02092443 0,07495364 ! neural plate morphogenesis GO:0001839 7 5 0,000 0,02092443 0,0748439 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 0,02092443 0,07473448 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,02092443 0,07462538 ! T cell activation during immune response GO:0002286 9 5 0,000 0,02092443 0,0745166 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,02092443 0,07440813 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,02092443 0,07429998 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 0,02092443 0,07419214 ! neuroprotection GO:0043526 8 5 0,000 0,02092443 0,07408462 ! regulation of sensory perception GO:0051931 8 5 0,000 0,02092443 0,0739774 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,02092443 0,0738705 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,02092443 0,0737639 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 0,02092443 0,07365761 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 0,02092443 0,07355163 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,02092443 0,07344596 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 0,02092443 0,07334058 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,02092443 0,07323551 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 0,02092443 0,07313074 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 0,02092443 0,07302626 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,02092443 0,07292209 ! spindle assembly GO:0051225 6 5 0,000 0,02092443 0,07281821 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,02092443 0,07271463 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,02092443 0,07261134 ! protein palmitoylation GO:0018345 12 5 0,000 0,02092443 0,07250835 ! drug metabolic process GO:0017144 7 5 0,000 0,02092443 0,07240564 ! organ regeneration GO:0031100 7 5 0,000 0,02092443 0,07230323 ! carnitine metabolic process GO:0009437 8 5 0,000 0,02092443 0,07220111 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,02092443 0,07209927 ! positive regulation of growth GO:0045927 96 53 1,000 0,02118085 0,07288003 ! chromatin remodeling GO:0006338 122 53 1,000 0,02118085 0,07277753 ! regulation of neuron apoptosis GO:0043523 117 53 1,000 0,02118085 0,07267532 ! synapse organization GO:0050808 102 53 1,000 0,02118085 0,07257339 ! protein amino acid lipidation GO:0006497 109 54 1,000 0,02193548 0,07505374 ! activation of phospholipase C activity GO:0007202 110 54 1,000 0,02193548 0,07494877 GO:0010863|positive regulation of phospholipase C activity, ! neuromuscular process GO:0050905 107 54 1,000 0,02193548 0,07484409 ! embryonic skeletal system development GO:0048706 101 54 1,000 0,02193548 0,07473971 ! membrane fusion GO:0006944 122 54 1,000 0,02193548 0,07463561 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 1,000 0,02193548 0,07453181 ! regulation of cell shape GO:0008360 142 54 1,000 0,02193548 0,07442829 ! positive regulation of phospholipase activity GO:0010518 111 55 1,000 0,02270113 0,07691937 ! cell maturation GO:0048469 107 55 1,000 0,02270113 0,07681283 ! skeletal muscle fiber development GO:0048741 130 56 1,000 0,02347771 0,07933064 ! regulation of protein catabolic process GO:0042176 126 56 1,000 0,02347771 0,07922107 ! regulation of bone remodeling GO:0046850 143 57 1,000 0,02426512 0,08176507 ! muscle fiber development GO:0048747 131 57 1,000 0,02426512 0,08165245 ! regulation of phospholipase activity GO:0010517 113 57 1,000 0,02426512 0,08154013 ! nucleotide-excision repair GO:0006289 91 57 1,000 0,02426512 0,08142813 ! regulation of intracellular transport GO:0032386 108 57 1,000 0,02426512 0,08131643 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,02505683 0,08385457 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,02505683 0,08373986 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 0,02505683 0,08362546 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 0,02505683 0,08351137 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,02505683 0,0833976 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 0,02505683 0,08328413 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 0,02505683 0,08317097 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,02505683 0,08305812 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 0,02505683 0,08294558 ! response to oxygen radical GO:0000305 11 6 0,000 0,02505683 0,08283334 ! positive regulation of axon extension GO:0045773 13 6 0,000 0,02505683 0,0827214 ! myoblast cell fate commitment GO:0048625 18 6 0,000 0,02505683 0,08260977 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 0,02505683 0,08249843 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 0,02505683 0,0823874 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,02505683 0,08227666 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,02505683 0,08216622 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 0,02505683 0,08205608 ! forebrain regionalization GO:0021871 9 6 0,000 0,02505683 0,08194623 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,02505683 0,08183668 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,02505683 0,08172742 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 0,02505683 0,08161845 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,02505683 0,08150977 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 0,02505683 0,08140138 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 0,02505683 0,08129327 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,02505683 0,08118546 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 0,02505683 0,08107793 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 0,02505683 0,08097068 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,02505683 0,08086372 ! malate metabolic process GO:0006108 13 6 0,000 0,02505683 0,08075704 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 0,02505683 0,08065064 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 0,02505683 0,08054452 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 0,02505683 0,08043868 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 0,02505683 0,08033312 ! protein refolding GO:0042026 15 6 0,000 0,02505683 0,08022783 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,02505683 0,08012282 ! opsonization GO:0008228 8 6 0,000 0,02505683 0,08001809 ! mating behavior GO:0007617 7 6 0,000 0,02505683 0,07991362 ! erythrocyte maturation GO:0043249 8 6 0,000 0,02505683 0,07980943 ! embryonic hemopoiesis GO:0035162 16 6 0,000 0,02505683 0,07970552 ! protein amino acid dealkylation GO:0008214 15 6 0,000 0,02505683 0,07960187 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 0,02505683 0,07949849 GO:0046530|photoreceptor cell differentiation, ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,02505683 0,07939538 ! response to interferon-gamma GO:0034341 16 6 0,000 0,02505683 0,07929253 ! toxin metabolic process GO:0009404 11 6 0,000 0,02505683 0,07918996 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,02505683 0,07908764 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 0,02505683 0,07898559 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 0,02505683 0,07888381 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 13 6 0,000 0,02505683 0,07878229 ! cGMP-mediated signaling GO:0019934 14 6 0,000 0,02505683 0,07868102 ! dorsal spinal cord development GO:0021516 10 6 0,000 0,02505683 0,07858002 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,02505683 0,07847928 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 0,02505683 0,07837879 ! thymic T cell selection GO:0045061 16 6 0,000 0,02505683 0,07827856 ! sphingoid catabolic process GO:0046521 8 6 0,000 0,02505683 0,07817859 ! protein lipoylation GO:0009249 10 6 0,000 0,02505683 0,07807887 ! transepithelial chloride transport GO:0030321 12 6 0,000 0,02505683 0,07797941 GO:0070633|transepithelial transport, ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,02505683 0,0778802 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 0,02505683 0,07778124 ! glutamate catabolic process GO:0006538 12 6 0,000 0,02505683 0,07768253 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 0,02505683 0,07758408 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,02505683 0,07748587 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 0,02505683 0,07738791 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,02505683 0,0772902 ! hyperosmotic response GO:0006972 10 6 0,000 0,02505683 0,07719273 ! L-serine biosynthetic process GO:0006564 7 6 0,000 0,02505683 0,07709551 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 0,02505683 0,07699854 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 0,02505683 0,0769018 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,02505683 0,07680531 ! urea metabolic process GO:0019627 7 6 0,000 0,02505683 0,07670907 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,02505683 0,07661306 ! neutrophil activation GO:0042119 7 6 0,000 0,02505683 0,07651729 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,02505683 0,07642177 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 0,02505683 0,07632648 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,02505683 0,07623143 ! paraxial mesoderm development GO:0048339 16 6 0,000 0,02505683 0,07613661 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 0,02505683 0,07604203 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,02505683 0,07594769 ! neuron apoptosis GO:0051402 15 6 0,000 0,02505683 0,07585358 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,02505683 0,0757597 ! T cell mediated immunity GO:0002456 17 6 0,000 0,02505683 0,07566605 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,02505683 0,07557264 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 0,02505683 0,07547945 ! carnitine transport GO:0015879 10 6 0,000 0,02505683 0,0753865 GO:0015838|betaine transport, ! positive regulation of exocytosis GO:0045921 11 6 0,000 0,02505683 0,07529377 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 0,02505683 0,07520127 ! early endosome to late endosome transport GO:0045022 16 6 0,000 0,02505683 0,075109 ! 5S class rRNA transcription GO:0042791 13 6 0,000 0,02505683 0,07501696 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,02505683 0,07492514 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 0,02505683 0,07483354 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 0,02505683 0,07474217 ! sodium ion homeostasis GO:0055078 12 6 0,000 0,02505683 0,07465102 ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 0,02505683 0,07456009 ! neural nucleus development GO:0048857 19 6 0,000 0,02505683 0,07446939 ! response to UV-C GO:0010225 14 6 0,000 0,02505683 0,0743789 ! astrocyte development GO:0014002 16 6 0,000 0,02505683 0,07428864 ! protein targeting to lysosome GO:0006622 12 6 0,000 0,02505683 0,07419859 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,02505683 0,07410876 ! interaction with symbiont GO:0051702 14 6 0,000 0,02505683 0,07401915 ! regulation of dendrite development GO:0050773 16 6 0,000 0,02505683 0,07392975 ! peptidyl-arginine modification GO:0018195 13 6 0,000 0,02505683 0,07384057 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 0,02505683 0,07375161 ! response to copper ion GO:0046688 10 6 0,000 0,02505683 0,07366286 ! response to exogenous dsRNA GO:0043330 13 6 0,000 0,02505683 0,07357432 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 0,02505683 0,073486 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,02505683 0,07339788 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 0,02505683 0,07330998 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,02505683 0,07322229 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 0,02505683 0,07313481 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,02505683 0,07304754 ! nucleoside catabolic process GO:0009164 10 6 0,000 0,02505683 0,07296047 ! hair follicle maturation GO:0048820 8 6 0,000 0,02505683 0,07287361 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,02505683 0,07278696 ! Schwann cell development GO:0014044 15 6 0,000 0,02505683 0,07270052 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 0,02505683 0,07261428 ! response to pheromone GO:0019236 6 6 0,000 0,02505683 0,07252824 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 0,02505683 0,07244241 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 0,02505683 0,07235678 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 0,02505683 0,07227135 ! base conversion or substitution editing GO:0016553 6 6 0,000 0,02505683 0,07218613 ! subpallium development GO:0021544 15 6 0,000 0,02505683 0,0721011 ! neural tube patterning GO:0021532 8 6 0,000 0,02505683 0,07201628 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 0,02505683 0,07193165 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 0,02505683 0,07184723 ! maintenance of organ identity GO:0048496 9 6 0,000 0,02505683 0,071763 ! G2 phase GO:0051319 16 6 0,000 0,02505683 0,07167896 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 0,02505683 0,07159513 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 0,02505683 0,07151149 ! oxygen homeostasis GO:0032364 10 6 0,000 0,02505683 0,07142805 ! establishment of planar polarity GO:0001736 7 6 0,000 0,02505683 0,0713448 ! regulation of mast cell activation GO:0033003 13 6 0,000 0,02505683 0,07126174 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,02505683 0,07117888 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 0,02505683 0,07109621 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,02505683 0,07101373 ! receptor internalization GO:0031623 11 6 0,000 0,02505683 0,07093144 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 0,02505683 0,07084935 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 0,02505683 0,07076744 ! neutrophil homeostasis GO:0001780 11 6 0,000 0,02505683 0,07068572 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,02505683 0,07060419 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 0,02505683 0,07052285 ! protein deubiquitination GO:0016579 16 6 0,000 0,02505683 0,0704417 ! protein destabilization GO:0031648 9 6 0,000 0,02505683 0,07036073 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 0,02505683 0,07027995 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,02505683 0,07019935 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 0,02505683 0,07011894 ! regulation of viral transcription GO:0046782 11 6 0,000 0,02505683 0,07003871 ! progesterone metabolic process GO:0042448 12 6 0,000 0,02505683 0,06995867 ! negative regulation of axon extension GO:0030517 24 6 0,000 0,02505683 0,06987881 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 0,02505683 0,06979913 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 0,02505683 0,06971963 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,02505683 0,06964031 ! determination of adult lifespan GO:0008340 17 6 0,000 0,02505683 0,06956118 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 0,02505683 0,06948222 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 0,02505683 0,06940344 ! neural plate development GO:0001840 9 6 0,000 0,02505683 0,06932484 ! catecholamine transport GO:0051937 9 6 0,000 0,02505683 0,06924642 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 0,02505683 0,06916818 ! sensory cilium assembly GO:0035058 10 6 0,000 0,02505683 0,06909011 ! organ or tissue specific immune response GO:0002251 8 6 0,000 0,02505683 0,06901222 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 0,02505683 0,0689345 ! maternal placenta development GO:0001893 12 6 0,000 0,02505683 0,06885696 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 0,02505683 0,06877959 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,02505683 0,0687024 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 0,02505683 0,06862538 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 0,02505683 0,06854853 ! positive regulation of coagulation GO:0050820 13 6 0,000 0,02505683 0,06847185 ! cellular anion homeostasis GO:0030002 11 6 0,000 0,02505683 0,06839535 GO:0055081|anion homeostasis, ! cellular polysaccharide metabolic process GO:0044264 93 58 1,000 0,02506324 0,06833648 ! lipoprotein biosynthetic process GO:0042158 115 58 1,000 0,02506324 0,0682603 ! regulation of tissue remodeling GO:0034103 146 58 1,000 0,02506324 0,06818429 ! positive regulation of lipase activity GO:0060193 115 58 1,000 0,02506324 0,06810844 ! establishment of organelle localization GO:0051656 122 59 1,000 0,02587197 0,07022804 ! regulation of neurotransmitter levels GO:0001505 113 60 1,000 0,02669122 0,07237143 ! lipid modification GO:0030258 112 60 1,000 0,02669122 0,0722912 ! kidney development GO:0001822 133 60 1,000 0,02669122 0,07221114 ! positive regulation of secretion GO:0051047 110 61 1,000 0,02752088 0,07437336 ! camera-type eye development GO:0043010 126 61 1,000 0,02752088 0,07429118 ! viral reproductive process GO:0022415 132 62 1,000 0,02836085 0,07647413 ! DNA damage response, signal transduction GO:0042770 136 62 1,000 0,02836085 0,07638982 ! tRNA transcription GO:0009304 17 7 0,000 0,0291719 0,07848784 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 0,0291719 0,0784015 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 0,0291719 0,07831534 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,0291719 0,07822937 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 0,0291719 0,0781436 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,0291719 0,07805801 ! sleep GO:0030431 16 7 0,000 0,0291719 0,0779726 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,0291719 0,07788739 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 0,0291719 0,07780236 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,0291719 0,07771751 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,0291719 0,07763285 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,0291719 0,07754838 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,0291719 0,07746409 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,0291719 0,07737998 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,0291719 0,07729605 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,0291719 0,07721231 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,0291719 0,07712874 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,0291719 0,07704536 ! SMAD protein complex assembly GO:0007183 13 7 0,000 0,0291719 0,07696216 ! glycolipid transport GO:0046836 11 7 0,000 0,0291719 0,07687914 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,0291719 0,07679629 GO:0051923|sulfation, ! neuron adhesion GO:0007158 14 7 0,000 0,0291719 0,07671363 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,0291719 0,07663114 ! establishment of tissue polarity GO:0007164 8 7 0,000 0,0291719 0,07654883 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 0,0291719 0,0764667 ! pericardium development GO:0060039 16 7 0,000 0,0291719 0,07638474 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 0,0291719 0,07630296 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 0,0291719 0,07622135 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 0,0291719 0,07613991 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 0,0291719 0,07605866 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,0291719 0,07597757 ! lipoprotein transport GO:0042953 14 7 0,000 0,0291719 0,07589666 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,0291719 0,07581591 ! rhythmic behavior GO:0007622 17 7 0,000 0,0291719 0,07573535 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 0,0291719 0,07565495 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 0,0291719 0,07557472 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,0291719 0,07549466 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 0,0291719 0,07541477 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,0291719 0,07533505 ! regulation of odontogenesis GO:0042481 14 7 0,000 0,0291719 0,0752555 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,0291719 0,07517612 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 0,0291719 0,0750969 ! mechanosensory behavior GO:0007638 16 7 0,000 0,0291719 0,07501785 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 0,0291719 0,07493897 ! positive regulation of isotype switching GO:0045830 17 7 0,000 0,0291719 0,07486025 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 0,0291719 0,0747817 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,0291719 0,07470331 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,0291719 0,07462509 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,0291719 0,07454703 ! spinal cord patterning GO:0021511 14 7 0,000 0,0291719 0,07446913 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 0,0291719 0,0743914 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,0291719 0,07431383 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,0291719 0,07423642 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 0,0291719 0,07415917 ! adrenal gland development GO:0030325 17 7 0,000 0,0291719 0,07408208 ! cysteine metabolic process GO:0006534 13 7 0,000 0,0291719 0,07400515 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 0,0291719 0,07392838 ! ovulation GO:0030728 10 7 0,000 0,0291719 0,07385177 ! adenohypophysis development GO:0021984 11 7 0,000 0,0291719 0,07377532 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 0,0291719 0,07369903 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 0,0291719 0,07362289 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 0,0291719 0,07354691 ! microtubule nucleation GO:0007020 21 7 0,000 0,0291719 0,07347109 ! proline biosynthetic process GO:0006561 10 7 0,000 0,0291719 0,07339543 ! tryptophan metabolic process GO:0006568 11 7 0,000 0,0291719 0,07331992 ! thyroid hormone generation GO:0006590 13 7 0,000 0,0291719 0,07324456 ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,0291719 0,07316936 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,0291719 0,07309432 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,0291719 0,07301943 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,0291719 0,07294469 ! galactose metabolic process GO:0006012 13 7 0,000 0,0291719 0,0728701 ! vesicle fusion GO:0006906 20 7 0,000 0,0291719 0,07279567 ! response to dietary excess GO:0002021 8 7 0,000 0,0291719 0,07272139 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,0291719 0,07264726 ! intracellular pH reduction GO:0051452 13 7 0,000 0,0291719 0,07257328 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,0291719 0,07249945 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 0,0291719 0,07242577 ! organ growth GO:0035265 15 7 0,000 0,0291719 0,07235224 ! nucleoside transport GO:0015858 11 7 0,000 0,0291719 0,07227886 ! nucleoside salvage GO:0043174 11 7 0,000 0,0291719 0,07220563 GO:0006166|purine ribonucleoside salvage, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,0291719 0,07213255 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 0,0291719 0,07205962 ! parturition GO:0007567 16 7 0,000 0,0291719 0,07198683 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 0,0291719 0,07191419 ! rRNA modification GO:0000154 14 7 0,000 0,0291719 0,07184169 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,0291719 0,07176935 ! spindle checkpoint GO:0031577 16 7 0,000 0,0291719 0,07169714 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,0291719 0,07162509 ! monocyte differentiation GO:0030224 16 7 0,000 0,0291719 0,07155317 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,0291719 0,0714814 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,0291719 0,07140978 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 0,0291719 0,0713383 ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,0291719 0,07126696 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,0291719 0,07119576 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,0291719 0,07112471 ! eating behavior GO:0042755 8 7 0,000 0,0291719 0,0710538 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,0291719 0,07098303 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 0,0291719 0,0709124 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 0,0291719 0,07084191 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,0291719 0,07077156 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 0,0291719 0,07070135 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,0291719 0,07063128 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 0,0291719 0,07056135 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 0,0291719 0,07049155 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 0,0291719 0,0704219 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 0,0291719 0,07035238 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,0291719 0,070283 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 0,0291719 0,07021375 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,0291719 0,07014465 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,0291719 0,07007567 ! histone ubiquitination GO:0016574 9 7 0,000 0,0291719 0,07000684 ! regulation of meiosis GO:0040020 12 7 0,000 0,0291719 0,06993814 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 0,0291719 0,06986957 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 0,0291719 0,06980114 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,0291719 0,06973284 ! membrane to membrane docking GO:0022614 14 7 0,000 0,0291719 0,06966467 ! transcription termination GO:0006353 14 7 0,000 0,0291719 0,06959664 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,0291719 0,06952874 ! anaphase GO:0051322 18 7 0,000 0,0291719 0,06946097 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 0,0291719 0,06939334 ! axonal fasciculation GO:0007413 19 7 0,000 0,0291719 0,06932584 ! negative regulation of nuclear division GO:0051784 15 7 0,000 0,0291719 0,06925846 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 0,0291719 0,06919122 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,0291719 0,06912411 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 0,0291719 0,06905713 ! diuresis GO:0030146 12 7 0,000 0,0291719 0,06899028 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,0291719 0,06892356 ! thiamin metabolic process GO:0006772 7 7 0,000 0,0291719 0,06885697 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,0291719 0,0687905 ! antibiotic transport GO:0042891 9 7 0,000 0,0291719 0,06872417 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,0291719 0,06865796 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 0,0291719 0,06859188 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 0,0291719 0,06852592 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 0,0291719 0,0684601 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,0291719 0,0683944 ! melanin biosynthetic process GO:0042438 10 7 0,000 0,0291719 0,06832882 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 0,0291719 0,06826337 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,0291719 0,06819805 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,0291719 0,06813285 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 0,0291719 0,06806777 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,0291719 0,06800282 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 0,0291719 0,067938 ! endosome to lysosome transport GO:0008333 12 7 0,000 0,0291719 0,0678733 ! protein modification by small protein removal GO:0070646 19 7 0,000 0,0291719 0,06780872 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 0,0291719 0,06774426 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,0291719 0,06767992 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 0,0291719 0,06761571 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,0291719 0,06755162 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,0291719 0,06748765 ! muscle adaptation GO:0043500 13 7 0,000 0,0291719 0,0674238 ! embryonic heart tube development GO:0035050 14 7 0,000 0,0291719 0,06736008 ! retina homeostasis GO:0001895 12 7 0,000 0,0291719 0,06729647 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 0,0291719 0,06723298 ! protein amino acid prenylation GO:0018346 19 7 0,000 0,0291719 0,06716961 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 0,0291719 0,06710637 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 0,0291719 0,06704324 ! glycerophospholipid biosynthetic process GO:0046474 116 64 1,000 0,03007132 0,06904533 ! lymphocyte mediated immunity GO:0002449 122 65 1,000 0,03094162 0,07097687 ! ear development GO:0043583 114 66 1,000 0,03182182 0,0729275 ! steroid hormone receptor signaling pathway GO:0030518 146 66 1,000 0,03182182 0,07285915 ! embryonic limb morphogenesis GO:0030326 139 67 1,000 0,03271185 0,07482682 GO:0035113|embryonic appendage morphogenesis, ! secondary metabolic process GO:0019748 125 67 1,000 0,03271185 0,07475682 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,03326972 0,07596069 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,03326972 0,07588976 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 0,03326972 0,07581897 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 0,03326972 0,07574831 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,03326972 0,07567778 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,03326972 0,07560738 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,03326972 0,07553711 ! male meiosis GO:0007140 9 8 0,000 0,03326972 0,07546698 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,03326972 0,07539697 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,03326972 0,07532709 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,03326972 0,07525735 ! meiotic prophase I GO:0007128 14 8 0,000 0,03326972 0,07518773 ! response to zinc ion GO:0010043 12 8 0,000 0,03326972 0,07511824 ! regulation of lipid kinase activity GO:0043550 17 8 0,000 0,03326972 0,07504888 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,03326972 0,07497964 ! oligopeptide transport GO:0006857 16 8 0,000 0,03326972 0,07491054 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,03326972 0,07484156 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,03326972 0,07477271 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,03326972 0,07470398 ! signal peptide processing GO:0006465 12 8 0,000 0,03326972 0,07463538 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,03326972 0,07456691 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,03326972 0,07449856 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,03326972 0,07443034 ! succinate metabolic process GO:0006105 17 8 0,000 0,03326972 0,07436224 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,03326972 0,07429427 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,03326972 0,07422642 ! estrogen metabolic process GO:0008210 17 8 0,000 0,03326972 0,0741587 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,03326972 0,0740911 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,03326972 0,07402362 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,03326972 0,07395626 ! reflex GO:0060004 17 8 0,000 0,03326972 0,07388903 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,03326972 0,07382192 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,03326972 0,07375493 ! hemoglobin metabolic process GO:0020027 14 8 0,000 0,03326972 0,07368806 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,03326972 0,07362132 ! pigment granule organization GO:0048753 17 8 0,000 0,03326972 0,07355469 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,03326972 0,07348819 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,03326972 0,0734218 ! astrocyte differentiation GO:0048708 19 8 0,000 0,03326972 0,07335554 ! histidine catabolic process GO:0006548 10 8 0,000 0,03326972 0,07328939 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,03326972 0,07322336 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,03326972 0,07315746 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,03326972 0,07309167 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,03326972 0,073026 ! regulation of pigmentation during development GO:0048070 25 8 0,000 0,03326972 0,07296044 ! melanin metabolic process GO:0006582 17 8 0,000 0,03326972 0,07289501 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,03326972 0,07282969 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,03326972 0,07276449 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,03326972 0,0726994 ! macrophage activation GO:0042116 13 8 0,000 0,03326972 0,07263444 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,03326972 0,07256958 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! purine salvage GO:0043101 12 8 0,000 0,03326972 0,07250485 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,03326972 0,07244023 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,03326972 0,07237572 ! osteoblast development GO:0002076 17 8 0,000 0,03326972 0,07231133 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,03326972 0,07224705 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,03326972 0,07218289 ! Schwann cell differentiation GO:0014037 21 8 0,000 0,03326972 0,07211884 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,03326972 0,07205491 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,03326972 0,07199108 ! response to UV-B GO:0010224 17 8 0,000 0,03326972 0,07192737 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,03326972 0,07186378 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,03326972 0,07180029 ! intermediate filament organization GO:0045109 12 8 0,000 0,03326972 0,07173692 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,03326972 0,07167366 ! cellular extravasation GO:0045123 13 8 0,000 0,03326972 0,07161051 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,03326972 0,07154748 ! response to antibiotic GO:0046677 11 8 0,000 0,03326972 0,07148455 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,03326972 0,07142173 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,03326972 0,07135903 ! response to tropane GO:0014073 15 8 0,000 0,03326972 0,07129643 GO:0042220|response to cocaine, ! melanosome transport GO:0032402 13 8 0,000 0,03326972 0,07123395 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,03326972 0,07117157 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,03326972 0,0711093 ! mast cell activation GO:0045576 14 8 0,000 0,03326972 0,07104714 ! multicellular organismal aging GO:0010259 20 8 0,000 0,03326972 0,07098509 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 0,03326972 0,07092315 ! gas homeostasis GO:0033483 14 8 0,000 0,03326972 0,07086132 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,03326972 0,07079959 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,03326972 0,07073798 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,03326972 0,07067646 ! nucleosome disassembly GO:0006337 14 8 0,000 0,03326972 0,07061506 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,03326972 0,07055376 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 0,03326972 0,07049257 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,03326972 0,07043148 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,03326972 0,07037051 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,03326972 0,07030963 ! intracellular lipid transport GO:0032365 16 8 0,000 0,03326972 0,07024886 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,03326972 0,0701882 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,03326972 0,07012764 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 0,03326972 0,07006718 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,03326972 0,07000683 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 0,03326972 0,06994659 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,03326972 0,06988644 ! hormone catabolic process GO:0042447 17 8 0,000 0,03326972 0,0698264 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,03326972 0,06976647 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,03326972 0,06970663 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,03326972 0,0696469 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,03326972 0,06958727 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,03326972 0,06952774 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,03326972 0,06946832 ! adult feeding behavior GO:0008343 10 8 0,000 0,03326972 0,069409 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,03326972 0,06934977 ! ATP catabolic process GO:0006200 11 8 0,000 0,03326972 0,06929065 ! blastocyst growth GO:0001832 19 8 0,000 0,03326972 0,06923163 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,03326972 0,06917271 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,03326972 0,06911389 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,03326972 0,06905517 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,03326972 0,06899655 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,03326972 0,06893803 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,03326972 0,0688796 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,03326972 0,06882128 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,03326972 0,06876306 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,03326972 0,06870493 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 0,03326972 0,0686469 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,03326972 0,06858897 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 0,03326972 0,06853114 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,03326972 0,06847341 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,03326972 0,06841577 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 0,03326972 0,06835823 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 0,03326972 0,06830078 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,03326972 0,06824344 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 0,03326972 0,06818619 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 0,03326972 0,06812903 ! negative regulation of ligase activity GO:0051352 116 68 1,000 0,03361158 0,06877144 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! detection of external stimulus GO:0009581 102 68 1,000 0,03361158 0,06871389 ! viral reproduction GO:0016032 142 68 1,000 0,03361158 0,06865644 ! regulation of lipase activity GO:0060191 137 68 1,000 0,03361158 0,06859908 ! adaptive immune response GO:0002250 126 68 1,000 0,03361158 0,06854182 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! cell projection assembly GO:0030031 138 68 1,000 0,03361158 0,06848465 ! cellular hormone metabolic process GO:0034754 120 69 1,000 0,03452094 0,07027888 ! developmental maturation GO:0021700 128 69 1,000 0,03452094 0,07022037 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 1,000 0,03636813 0,07391626 ! appendage morphogenesis GO:0035107 150 72 1,000 0,03730577 0,07575894 GO:0035108|limb morphogenesis, ! B cell activation GO:0042113 179 72 1,000 0,03730577 0,07569601 ! axon extension GO:0048675 16 9 0,000 0,03735036 0,07572359 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,03735036 0,07566081 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 0,03735036 0,07559812 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,03735036 0,07553554 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,03735036 0,07547306 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,03735036 0,07541069 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,03735036 0,07534842 ! reproductive behavior GO:0019098 22 9 0,000 0,03735036 0,07528625 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,03735036 0,07522418 ! Golgi to endosome transport GO:0006895 25 9 0,000 0,03735036 0,07516222 ! UTP metabolic process GO:0046051 10 9 0,000 0,03735036 0,07510035 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,03735036 0,07503859 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,03735036 0,07497694 ! artery development GO:0060840 25 9 0,000 0,03735036 0,07491538 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,03735036 0,07485392 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,03735036 0,07479257 ! equilibrioception GO:0050957 20 9 0,000 0,03735036 0,07473131 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,03735036 0,07467016 ! chemosensory behavior GO:0007635 21 9 0,000 0,03735036 0,0746091 ! microtubule bundle formation GO:0001578 22 9 0,000 0,03735036 0,07454815 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,03735036 0,07448729 ! leukocyte degranulation GO:0043299 16 9 0,000 0,03735036 0,07442653 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,03735036 0,07436588 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,03735036 0,07430532 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,03735036 0,07424486 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,03735036 0,0741845 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,03735036 0,07412423 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,03735036 0,07406407 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,03735036 0,074004 ! protein targeting to ER GO:0045047 25 9 0,000 0,03735036 0,07394403 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,03735036 0,07388415 ! T cell selection GO:0045058 27 9 0,000 0,03735036 0,07382438 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,03735036 0,0737647 ! glycine catabolic process GO:0006546 15 9 0,000 0,03735036 0,07370511 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,03735036 0,07364563 ! endosome organization GO:0007032 20 9 0,000 0,03735036 0,07358623 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,03735036 0,07352694 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,03735036 0,07346774 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,03735036 0,07340863 ! mannose metabolic process GO:0006013 13 9 0,000 0,03735036 0,07334962 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,03735036 0,07329071 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,03735036 0,07323189 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 0,03735036 0,07317316 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,03735036 0,07311453 ! receptor clustering GO:0043113 20 9 0,000 0,03735036 0,07305599 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,03735036 0,07299754 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,03735036 0,07293919 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,03735036 0,07288094 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,03735036 0,07282277 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,03735036 0,0727647 ! macrophage differentiation GO:0030225 15 9 0,000 0,03735036 0,07270672 ! oligodendrocyte development GO:0014003 11 9 0,000 0,03735036 0,07264883 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 0,03735036 0,07259104 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,03735036 0,07253333 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,03735036 0,07247572 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,03735036 0,0724182 ! response to amine stimulus GO:0014075 13 9 0,000 0,03735036 0,07236077 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,03735036 0,07230343 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,03735036 0,07224618 ! erythrocyte development GO:0048821 17 9 0,000 0,03735036 0,07218903 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,03735036 0,07213196 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,03735036 0,07207499 ! renal water homeostasis GO:0003091 15 9 0,000 0,03735036 0,0720181 ! postreplication repair GO:0006301 25 9 0,000 0,03735036 0,0719613 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,03735036 0,0719046 ! icosanoid secretion GO:0032309 15 9 0,000 0,03735036 0,07184798 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,03735036 0,07179145 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,03735036 0,07173501 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,03735036 0,07167866 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,03735036 0,0716224 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,03735036 0,07156622 ! sterol catabolic process GO:0016127 14 9 0,000 0,03735036 0,07151013 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,03735036 0,07145414 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,03735036 0,07139822 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,03735036 0,0713424 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,03735036 0,07128667 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 0,03735036 0,07123102 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,03735036 0,07117545 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 0,03735036 0,07111998 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,03735036 0,07106459 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,03735036 0,07100929 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,03735036 0,07095407 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,03735036 0,07089894 ! purine base metabolic process GO:0006144 25 9 0,000 0,03735036 0,07084389 ! pigment granule transport GO:0051904 17 9 0,000 0,03735036 0,07078893 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,03735036 0,07073406 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,03735036 0,07067927 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,03735036 0,07062456 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,03735036 0,07056994 ! mitochondrion localization GO:0051646 18 9 0,000 0,03735036 0,0705154 ! appendage development GO:0048736 151 73 1,000 0,03825265 0,07216311 GO:0060173|limb development, ! glycerolipid biosynthetic process GO:0045017 130 73 1,000 0,03825265 0,07210743 ! regulation of immune effector process GO:0002697 156 73 1,000 0,03825265 0,07205183 ! organelle localization GO:0051640 155 74 1,000 0,03920868 0,07379569 ! leukocyte mediated immunity GO:0002443 136 75 1,000 0,04017376 0,07555388 ! eye development GO:0001654 155 75 1,000 0,04017376 0,07549576 ! axon guidance GO:0007411 162 75 1,000 0,04017376 0,07543773 ! cell-matrix adhesion GO:0007160 181 76 1,000 0,0411478 0,07720742 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,04141389 0,07764707 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,04141389 0,07758752 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,04141389 0,07752807 ! associative learning GO:0008306 21 10 0,000 0,04141389 0,0774687 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,04141389 0,07740943 ! phosphate transport GO:0006817 24 10 0,000 0,04141389 0,07735025 ! cell volume homeostasis GO:0006884 17 10 0,000 0,04141389 0,07729116 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,04141389 0,07723216 ! CTP metabolic process GO:0046036 11 10 0,000 0,04141389 0,07717325 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 0,04141389 0,07711443 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,04141389 0,0770557 ! GTP metabolic process GO:0046039 11 10 0,000 0,04141389 0,07699705 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,04141389 0,0769385 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,04141389 0,07688004 ! social behavior GO:0035176 29 10 0,000 0,04141389 0,07682166 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,04141389 0,07676338 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,04141389 0,07670518 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,04141389 0,07664707 ! androgen metabolic process GO:0008209 17 10 0,000 0,04141389 0,07658905 ! phospholipid efflux GO:0033700 19 10 0,000 0,04141389 0,07653111 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,04141389 0,07647326 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,04141389 0,07641551 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,04141389 0,07635783 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,04141389 0,07630025 ! pathogenesis GO:0009405 17 10 0,000 0,04141389 0,07624275 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,04141389 0,07618534 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,04141389 0,07612801 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,04141389 0,07607077 ! endoderm development GO:0007492 18 10 0,000 0,04141389 0,07601362 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,04141389 0,07595655 ! arginine catabolic process GO:0006527 17 10 0,000 0,04141389 0,07589957 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,04141389 0,07584268 ! proline metabolic process GO:0006560 13 10 0,000 0,04141389 0,07578586 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,04141389 0,07572914 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 0,04141389 0,0756725 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,04141389 0,07561594 ! V(D)J recombination GO:0033151 34 10 0,000 0,04141389 0,07555947 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,04141389 0,07550308 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,04141389 0,07544678 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,04141389 0,07539056 ! B cell proliferation GO:0042100 19 10 0,000 0,04141389 0,07533442 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,04141389 0,07527837 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,04141389 0,0752224 ! multicellular organism growth GO:0035264 19 10 0,000 0,04141389 0,07516651 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,04141389 0,07511071 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,04141389 0,07505499 ! ruffle organization GO:0031529 17 10 0,000 0,04141389 0,07499935 ! epithelial cell development GO:0002064 21 10 0,000 0,04141389 0,0749438 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,04141389 0,07488833 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,04141389 0,07483294 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,04141389 0,07477763 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,04141389 0,0747224 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,04141389 0,07466725 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,04141389 0,07461219 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 13 10 0,000 0,04141389 0,07455721 ! brain morphogenesis GO:0048854 23 10 0,000 0,04141389 0,0745023 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,04141389 0,07444748 ! segment specification GO:0007379 15 10 0,000 0,04141389 0,07439274 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,04141389 0,07433808 ! blastoderm segmentation GO:0007350 19 10 0,000 0,04141389 0,0742835 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,04141389 0,074229 ! response to dsRNA GO:0043331 23 10 0,000 0,04141389 0,07417458 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,04141389 0,07412024 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,04141389 0,07406598 ! melanosome localization GO:0032400 16 10 0,000 0,04141389 0,0740118 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,04141389 0,0739577 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,04141389 0,07390367 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,04141389 0,07384973 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,04141389 0,07379586 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,04141389 0,07374208 ! induction of an organ GO:0001759 17 10 0,000 0,04141389 0,07368837 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,04141389 0,07363474 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,04141389 0,07358118 ! protein sumoylation GO:0016925 17 10 0,000 0,04141389 0,07352771 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,04141389 0,07347431 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,04141389 0,07342099 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,04141389 0,07336775 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,04141389 0,07331459 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,04141389 0,0732615 ! salivary gland development GO:0007431 28 10 0,000 0,04141389 0,07320849 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,04141389 0,07315555 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,04141389 0,07310269 ! midbrain development GO:0030901 14 10 0,000 0,04141389 0,07304991 ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,04141389 0,07299721 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,04141389 0,07294458 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,04141389 0,07289202 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,04141389 0,07283955 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,04141389 0,07278714 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,04141389 0,07273482 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,04141389 0,07268256 ! detection of calcium ion GO:0005513 24 10 0,000 0,04141389 0,07263039 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,04141389 0,07257828 ! blastocyst formation GO:0001825 18 10 0,000 0,04141389 0,07252626 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,04141389 0,0724743 ! cerebellar cortex development GO:0021695 16 10 0,000 0,04141389 0,07242243 ! positive regulation of amine transport GO:0051954 17 10 0,000 0,04141389 0,07237062 ! response to nicotine GO:0035094 20 10 0,000 0,04141389 0,07231889 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,04141389 0,07226723 ! neurotransmitter transport GO:0006836 142 77 1,000 0,0421307 0,0734656 ! lipoprotein metabolic process GO:0042157 147 78 1,000 0,04312239 0,07514122 ! positive regulation of lymphocyte activation GO:0051251 142 78 1,000 0,04312239 0,07508766 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 1,000 0,04412276 0,07677486 ! activation of protein kinase activity GO:0032147 170 80 1,000 0,04513173 0,0784746 ! development of primary sexual characteristics GO:0045137 143 80 1,000 0,04513173 0,07841878 ! negative regulation of organelle organization GO:0010639 181 80 1,000 0,04513173 0,07836305 ! respiratory burst GO:0045730 17 11 0,000 0,04546038 0,07887763 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,04546038 0,07882165 ! neuron fate specification GO:0048665 18 11 0,000 0,04546038 0,07876574 ! telencephalon cell migration GO:0022029 23 11 0,000 0,04546038 0,07870992 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,04546038 0,07865418 ! thyroid gland development GO:0030878 26 11 0,000 0,04546038 0,07859851 ! synapsis GO:0007129 14 11 0,000 0,04546038 0,07854293 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,04546038 0,07848742 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,04546038 0,07843199 ! response to pain GO:0048265 27 11 0,000 0,04546038 0,07837664 ! keratinocyte proliferation GO:0043616 19 11 0,000 0,04546038 0,07832137 ! bone resorption GO:0045453 16 11 0,000 0,04546038 0,07826617 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,04546038 0,07821106 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,04546038 0,07815602 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,04546038 0,07810105 ! melanocyte differentiation GO:0030318 20 11 0,000 0,04546038 0,07804617 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,04546038 0,07799136 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,04546038 0,07793663 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,04546038 0,07788198 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,04546038 0,0778274 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,04546038 0,0777729 ! UV protection GO:0009650 20 11 0,000 0,04546038 0,07771847 ! adult heart development GO:0007512 16 11 0,000 0,04546038 0,07766413 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,04546038 0,07760985 ! macroautophagy GO:0016236 19 11 0,000 0,04546038 0,07755566 ! temperature homeostasis GO:0001659 18 11 0,000 0,04546038 0,07750154 ! behavioral fear response GO:0001662 27 11 0,000 0,04546038 0,07744749 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,04546038 0,07739352 ! negative regulation of ossification GO:0030279 27 11 0,000 0,04546038 0,07733962 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,04546038 0,0772858 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,04546038 0,07723206 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,04546038 0,07717839 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,04546038 0,07712479 ! regulation of organ growth GO:0046620 14 11 0,000 0,04546038 0,07707127 ! pigment granule localization GO:0051875 20 11 0,000 0,04546038 0,07701782 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,04546038 0,07696445 ! vasoconstriction GO:0042310 20 11 0,000 0,04546038 0,07691115 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,04546038 0,07685792 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,04546038 0,07680477 ! embryonic axis specification GO:0000578 19 11 0,000 0,04546038 0,07675169 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,04546038 0,07669869 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,04546038 0,07664576 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,04546038 0,0765929 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,04546038 0,07654011 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,04546038 0,0764874 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,04546038 0,07643476 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,04546038 0,07638219 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,04546038 0,07632969 ! prophase GO:0051324 17 11 0,000 0,04546038 0,07627727 ! nucleosome positioning GO:0016584 15 11 0,000 0,04546038 0,07622491 ! regulation of isotype switching GO:0045191 24 11 0,000 0,04546038 0,07617263 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,04546038 0,07612042 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,04546038 0,07606829 ! apical protein localization GO:0045176 18 11 0,000 0,04546038 0,07601622 ! acid secretion GO:0046717 20 11 0,000 0,04546038 0,07596423 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,04546038 0,0759123 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,04546038 0,07586045 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,04546038 0,07580867 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,04546038 0,07575696 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,04546038 0,07570532 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 0,04546038 0,07565375 ! cholesterol efflux GO:0033344 21 11 0,000 0,04546038 0,07560225 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,04546038 0,07555082 ! oocyte development GO:0048599 20 11 0,000 0,04546038 0,07549946 ! germ cell migration GO:0008354 26 11 0,000 0,04546038 0,07544817 ! embryonic gut development GO:0048566 19 11 0,000 0,04546038 0,07539694 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,04546038 0,07534579 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,04546038 0,07529471 ! activation of innate immune response GO:0002218 16 11 0,000 0,04546038 0,0752437 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,04546038 0,07519276 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,04546038 0,07514188 ! lysogeny GO:0030069 22 11 0,000 0,04546038 0,07509107 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,04546038 0,07504034 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,04546038 0,07498967 ! sequestering of metal ion GO:0051238 15 11 0,000 0,04546038 0,07493907 ! nucleus localization GO:0051647 22 11 0,000 0,04546038 0,07488854 ! meiosis GO:0007126 143 81 1,000 0,0461492 0,07597204 GO:0051327|M phase of meiotic cell cycle, ! cell-substrate adhesion GO:0031589 189 82 1,000 0,0471751 0,0776086 ! protein import into nucleus GO:0006606 174 82 1,000 0,0471751 0,07755637 ! meiotic cell cycle GO:0051321 144 82 1,000 0,0471751 0,07750422 ! exocytosis GO:0006887 153 83 1,000 0,04820933 0,07915012 ! nuclear import GO:0051170 177 83 1,000 0,04820933 0,07909697 ! response to nutrient GO:0007584 135 84 1,000 0,0492518 0,08075311 ! digestion GO:0007586 130 84 1,000 0,0492518 0,08069895 ! regulation of ligase activity GO:0051340 147 84 1,000 0,0492518 0,08064487 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,0494899 0,08098045 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,0494899 0,08092625 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,0494899 0,08087212 ! mating GO:0007618 17 12 0,000 0,0494899 0,08081806 ! protein complex disassembly GO:0043241 28 12 0,000 0,0494899 0,08076407 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,0494899 0,08071016 ! regulation of cell projection assembly GO:0060491 33 12 0,000 0,0494899 0,08065632 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 0,000 0,0494899 0,08060255 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,0494899 0,08054885 ! T cell proliferation GO:0042098 32 12 0,000 0,0494899 0,08049522 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,0494899 0,08044166 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,0494899 0,08038818 ! ventral spinal cord development GO:0021517 25 12 0,000 0,0494899 0,08033476 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,0494899 0,08028142 ! drug transport GO:0015893 16 12 0,000 0,0494899 0,08022815 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,0494899 0,08017495 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,0494899 0,08012181 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,0494899 0,08006875 ! polyamine metabolic process GO:0006595 18 12 0,000 0,0494899 0,08001576 ! focal adhesion formation GO:0048041 37 12 0,000 0,0494899 0,07996284 ! mitotic spindle organization GO:0007052 23 12 0,000 0,0494899 0,07990999 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,0494899 0,07985721 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,0494899 0,0798045 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,0494899 0,07975186 ! lipid digestion GO:0044241 21 12 0,000 0,0494899 0,07969929 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,0494899 0,07964678 ! entry into host cell GO:0030260 34 12 0,000 0,0494899 0,07959435 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,0494899 0,07954199 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,0494899 0,07948969 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,0494899 0,07943746 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,0494899 0,0793853 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,0494899 0,07933321 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,0494899 0,07928119 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,0494899 0,07922924 ! snRNA metabolic process GO:0016073 30 12 0,000 0,0494899 0,07917735 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,0494899 0,07912554 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,0494899 0,07907379 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,0494899 0,0790221 ! cranial nerve development GO:0021545 23 12 0,000 0,0494899 0,07897049 ! fucose catabolic process GO:0019317 25 12 0,000 0,0494899 0,07891894 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,0494899 0,07886746 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,0494899 0,07881605 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 0,0494899 0,0787647 ! zymogen activation GO:0031638 18 12 0,000 0,0494899 0,07871342 ! T cell homeostasis GO:0043029 28 12 0,000 0,0494899 0,07866221 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,0494899 0,07861106 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,0494899 0,07855999 ! oocyte differentiation GO:0009994 21 12 0,000 0,0494899 0,07850897 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,0494899 0,07845803 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,0494899 0,07840715 ! defense response to fungus GO:0050832 15 12 0,000 0,0494899 0,07835633 ! developmental induction GO:0031128 22 12 0,000 0,0494899 0,07830558 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 21 12 0,000 0,0494899 0,0782549 ! lamellipodium assembly GO:0030032 24 12 0,000 0,0494899 0,07820428 ! response to cold GO:0009409 17 12 0,000 0,0494899 0,07815373 ! establishment of cell polarity GO:0030010 21 12 0,000 0,0494899 0,07810324 ! regulation of synapse organization GO:0050807 18 12 0,000 0,0494899 0,07805282 ! regulation of neuron differentiation GO:0045664 187 85 1,000 0,05030242 0,07928311 ! positive regulation of cell activation GO:0050867 161 86 1,000 0,05136112 0,08089956 GO:0002696|positive regulation of leukocyte activation, ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,05350252 0,08421821 ! cGMP metabolic process GO:0046068 18 13 0,000 0,05350252 0,08416398 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,05350252 0,08410982 ! regulation of chemokine production GO:0032642 18 13 0,000 0,05350252 0,08405573 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,05350252 0,08400171 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,05350252 0,08394776 ! peroxisomal transport GO:0043574 28 13 0,000 0,05350252 0,08389387 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,05350252 0,08384006 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,05350252 0,08378632 ! organelle fusion GO:0048284 36 13 0,000 0,05350252 0,08373264 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,05350252 0,08367904 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,05350252 0,0836255 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,05350252 0,08357203 ! positive regulation of cell growth GO:0030307 24 13 0,000 0,05350252 0,08351863 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,05350252 0,0834653 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,05350252 0,08341203 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,05350252 0,08335884 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,05350252 0,08330571 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,05350252 0,08325265 ! methionine metabolic process GO:0006555 31 13 0,000 0,05350252 0,08319965 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,05350252 0,08314673 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,05350252 0,08309387 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,05350252 0,08304108 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,05350252 0,08298835 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! cytokine metabolic process GO:0042107 24 13 0,000 0,05350252 0,0829357 ! cellular carbohydrate catabolic process GO:0044275 17 13 0,000 0,05350252 0,0828831 ! exocrine system development GO:0035272 34 13 0,000 0,05350252 0,08283058 ! asymmetric protein localization GO:0008105 24 13 0,000 0,05350252 0,08277812 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,05350252 0,08272573 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 0,05350252 0,08267341 ! L-glutamate transport GO:0015813 30 13 0,000 0,05350252 0,08262115 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,05350252 0,08256895 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,05350252 0,08251683 ! protein homotetramerization GO:0051289 24 13 0,000 0,05350252 0,08246477 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,05350252 0,08241277 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,05350252 0,08236084 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,05350252 0,08230898 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,05350252 0,08225718 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,05350252 0,08220544 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,05350252 0,08215377 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,05350252 0,08210217 ! histone methylation GO:0016571 29 13 0,000 0,05350252 0,08205063 ! chromatin silencing GO:0006342 29 13 0,000 0,05350252 0,08199916 ! gland morphogenesis GO:0022612 31 13 0,000 0,05350252 0,08194775 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,05350252 0,0818964 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 0,05350252 0,08184512 ! regulation of epidermis development GO:0045682 19 13 0,000 0,05350252 0,0817939 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,05350252 0,08174275 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,05350252 0,08169166 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,05350252 0,08164063 ! spleen development GO:0048536 24 13 0,000 0,05350252 0,08158967 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,05350252 0,08153877 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,05350252 0,08148794 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,05350252 0,08143717 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,05350252 0,08138646 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,05350252 0,08133582 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,05350252 0,08128523 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,05350252 0,08123471 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,05350252 0,08118426 ! insulin secretion GO:0030073 24 13 0,000 0,05350252 0,08113386 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,05350252 0,08108353 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 0,05350252 0,08103326 ! acrosome reaction GO:0007340 19 13 0,000 0,05350252 0,08098306 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,05350252 0,08093291 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,05350252 0,08088283 ! protein localization in nucleus GO:0034504 192 89 1,000 0,05458478 0,08246791 ! rRNA transcription GO:0009303 28 14 0,000 0,05749832 0,08681606 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,05749832 0,08676244 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 0,05749832 0,08670888 ! water transport GO:0006833 21 14 0,000 0,05749832 0,08665539 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,05749832 0,08660196 ! non-recombinational repair GO:0000726 29 14 0,000 0,05749832 0,0865486 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,05749832 0,08649531 ! hair follicle morphogenesis GO:0031069 27 14 0,000 0,05749832 0,08644208 ! RNA polyadenylation GO:0043631 32 14 0,000 0,05749832 0,08638892 ! lipid localization GO:0010876 32 14 0,000 0,05749832 0,08633582 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 0,05749832 0,08628279 ! regulated secretory pathway GO:0045055 24 14 0,000 0,05749832 0,08622982 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,05749832 0,08617692 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,05749832 0,08612409 ! arginine metabolic process GO:0006525 21 14 0,000 0,05749832 0,08607131 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,05749832 0,08601861 ! regulation of heart rate GO:0002027 25 14 0,000 0,05749832 0,08596596 ! fear response GO:0042596 34 14 0,000 0,05749832 0,08591339 ! organic alcohol transport GO:0015850 29 14 0,000 0,05749832 0,08586087 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,05749832 0,08580842 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 0,000 0,05749832 0,08575603 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,05749832 0,08570371 ! neutral amino acid transport GO:0015804 28 14 0,000 0,05749832 0,08565145 ! bone mineralization GO:0030282 18 14 0,000 0,05749832 0,08559926 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,05749832 0,08554713 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,05749832 0,08549506 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,05749832 0,08544306 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,05749832 0,08539112 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,05749832 0,08533924 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,05749832 0,08528742 ! ribosome assembly GO:0042255 18 14 0,000 0,05749832 0,08523567 ! cerebellum development GO:0021549 23 14 0,000 0,05749832 0,08518398 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,05749832 0,08513235 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,05749832 0,08508079 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,05749832 0,08502929 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,05749832 0,08497785 ! NADP metabolic process GO:0006739 24 14 0,000 0,05749832 0,08492647 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,05749832 0,08487516 ! oxygen transport GO:0015671 22 14 0,000 0,05749832 0,0848239 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,05749832 0,08477271 ! male genitalia development GO:0030539 26 14 0,000 0,05749832 0,08472158 ! regulation of axon extension GO:0030516 43 14 0,000 0,05749832 0,08467052 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,05749832 0,08461951 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 0,05749832 0,08456856 ! regulation of cell morphogenesis GO:0022604 243 93 1,000 0,05899082 0,08671154 ! vitamin metabolic process GO:0006766 153 93 1,000 0,05899082 0,0866594 ! carbohydrate biosynthetic process GO:0016051 158 94 1,000 0,06011104 0,08825197 ! phospholipid biosynthetic process GO:0008654 188 95 1,000 0,06123858 0,08985336 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,06147735 0,09014957 ! lactation GO:0007595 30 15 0,000 0,06147735 0,09009549 ! reproductive cellular process GO:0048610 22 15 0,000 0,06147735 0,09004147 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,06147735 0,08998752 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,06147735 0,08993364 ! superoxide anion generation GO:0042554 22 15 0,000 0,06147735 0,08987982 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,06147735 0,08982606 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,06147735 0,08977237 ! copper ion transport GO:0006825 22 15 0,000 0,06147735 0,08971874 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,06147735 0,08966518 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,06147735 0,08961168 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,06147735 0,08955824 ! sulfate transport GO:0008272 27 15 0,000 0,06147735 0,08950487 ! response to cAMP GO:0051591 25 15 0,000 0,06147735 0,08945156 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,06147735 0,08939832 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,06147735 0,08934514 ! regulation of mRNA processing GO:0050684 26 15 0,000 0,06147735 0,08929202 ! response to hexose stimulus GO:0009746 25 15 0,000 0,06147735 0,08923896 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,06147735 0,08918597 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,06147735 0,08913304 ! vesicle coating GO:0006901 38 15 0,000 0,06147735 0,08908018 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 0,06147735 0,08902737 ! regulation of exocytosis GO:0017157 26 15 0,000 0,06147735 0,08897463 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,06147735 0,08892195 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,06147735 0,08886934 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,06147735 0,08881678 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,06147735 0,08876429 ! regulation of vasodilation GO:0042312 27 15 0,000 0,06147735 0,08871186 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,06147735 0,08865949 ! histone deacetylation GO:0016575 24 15 0,000 0,06147735 0,08860718 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,06147735 0,08855494 ! water homeostasis GO:0030104 28 15 0,000 0,06147735 0,08850276 ! cofactor transport GO:0051181 30 15 0,000 0,06147735 0,08845063 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,06147735 0,08839857 ! muscle maintenance GO:0046716 26 15 0,000 0,06147735 0,08834657 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,06147735 0,08829464 ! intestinal absorption GO:0050892 31 15 0,000 0,06147735 0,08824276 ! dopamine metabolic process GO:0042417 35 15 0,000 0,06147735 0,08819094 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,06147735 0,08813919 ! heme biosynthetic process GO:0006783 33 15 0,000 0,06147735 0,08808749 ! lymphocyte homeostasis GO:0002260 33 15 0,000 0,06147735 0,08803586 ! epithelial to mesenchymal transition GO:0001837 30 15 0,000 0,06147735 0,08798429 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,06147735 0,08793277 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,06147735 0,08788132 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,06147735 0,08782993 ! actin filament polymerization GO:0030041 27 15 0,000 0,06147735 0,0877786 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,06147735 0,08772732 ! transcription initiation GO:0006352 171 97 1,000 0,06351528 0,0905825 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,06543971 0,09327258 ! positive regulation of cell size GO:0045793 29 16 0,000 0,06543971 0,09321819 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,06543971 0,09316387 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,06543971 0,09310961 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,06543971 0,09305541 ! bone remodeling GO:0046849 28 16 0,000 0,06543971 0,09300128 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 0,000 0,06543971 0,09294721 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,06543971 0,0928932 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,06543971 0,09283926 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,06543971 0,09278538 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,06543971 0,09273156 ! startle response GO:0001964 28 16 0,000 0,06543971 0,0926778 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,06543971 0,0926241 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,06543971 0,09257047 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,06543971 0,0925169 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,06543971 0,09246339 ! protein polyubiquitination GO:0000209 41 16 0,000 0,06543971 0,09240994 ! glutamate metabolic process GO:0006536 25 16 0,000 0,06543971 0,09235656 ! pituitary gland development GO:0021983 30 16 0,000 0,06543971 0,09230323 ! response to osmotic stress GO:0006970 27 16 0,000 0,06543971 0,09224997 ! lysosomal transport GO:0007041 31 16 0,000 0,06543971 0,09219677 ! fructose metabolic process GO:0006000 25 16 0,000 0,06543971 0,09214363 ! L-amino acid transport GO:0015807 33 16 0,000 0,06543971 0,09209055 ! stem cell development GO:0048864 46 16 0,000 0,06543971 0,09203754 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,06543971 0,09198458 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,06543971 0,09193169 ! intermediate filament-based process GO:0045103 36 16 0,000 0,06543971 0,09187885 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,06543971 0,09182608 ! negative regulation of immune response GO:0050777 38 16 0,000 0,06543971 0,09177337 ! axon cargo transport GO:0008088 46 16 0,000 0,06543971 0,09172071 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,06543971 0,09166812 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,06543971 0,09161559 ! positive regulation of protein import into nucleus GO:0042307 34 16 0,000 0,06543971 0,09156312 ! DNA replication initiation GO:0006270 28 16 0,000 0,06543971 0,09151071 ! neuron recognition GO:0008038 40 16 0,000 0,06543971 0,09145835 ! mRNA splice site selection GO:0006376 44 16 0,000 0,06543971 0,09140606 ! tissue regeneration GO:0042246 27 16 0,000 0,06543971 0,09135383 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,06543971 0,09130166 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,06543971 0,09124954 ! biomineral formation GO:0031214 22 16 0,000 0,06543971 0,09119749 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,06543971 0,0911455 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,06543971 0,09109356 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,06543971 0,09104169 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,06543971 0,09098987 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,06543971 0,09093811 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,06543971 0,09088641 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,06543971 0,09083477 ! peptide hormone processing GO:0016486 27 16 0,000 0,06543971 0,09078319 ! hormone metabolic process GO:0042445 171 100 1,000 0,06698322 0,09287173 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,06938544 0,09614783 ! metencephalon development GO:0022037 32 17 0,000 0,06938544 0,09609333 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,06938544 0,09603888 ! signal complex assembly GO:0007172 47 17 0,000 0,06938544 0,0959845 ! filopodium assembly GO:0046847 42 17 0,000 0,06938544 0,09593018 ! endothelial cell migration GO:0043542 31 17 0,000 0,06938544 0,09587592 ! gene silencing by RNA GO:0031047 38 17 0,000 0,06938544 0,09582172 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,06938544 0,09576759 ! glial cell development GO:0021782 28 17 0,000 0,06938544 0,09571351 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,06938544 0,0956595 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,06938544 0,09560554 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 0,000 0,06938544 0,09555165 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,06938544 0,09549782 ! myoblast differentiation GO:0045445 50 17 0,000 0,06938544 0,09544405 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,06938544 0,09539034 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,06938544 0,09533669 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,06938544 0,0952831 ! negative regulation of microtubule depolymerization GO:0007026 50 17 0,000 0,06938544 0,09522957 GO:0031114|regulation of microtubule depolymerization, ! NAD metabolic process GO:0019674 33 17 0,000 0,06938544 0,0951761 ! membrane budding GO:0006900 42 17 0,000 0,06938544 0,09512269 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,06938544 0,09506934 ! regulation of protein binding GO:0043393 33 17 0,000 0,06938544 0,09501605 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,06938544 0,09496282 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,06938544 0,09490965 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,06938544 0,09485654 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,06938544 0,09480348 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,06938544 0,09475049 ! steroid catabolic process GO:0006706 34 17 0,000 0,06938544 0,09469756 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,06938544 0,09464468 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,06938544 0,09459187 ! gas transport GO:0015669 26 17 0,000 0,06938544 0,09453911 ! organic cation transport GO:0015695 32 17 0,000 0,06938544 0,09448642 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,06938544 0,09443378 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,06938544 0,0943812 ! positive regulation of protein complex assembly GO:0031334 34 18 0,000 0,07331463 0,09967036 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,07331463 0,09961492 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,07331463 0,09955955 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,07331463 0,09950424 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,07331463 0,09944899 ! adult walking behavior GO:0007628 36 18 0,000 0,07331463 0,0993938 ! patterning of blood vessels GO:0001569 43 18 0,000 0,07331463 0,09933868 ! heart looping GO:0001947 34 18 0,000 0,07331463 0,09928361 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,07331463 0,0992286 ! centrosome cycle GO:0007098 26 18 0,000 0,07331463 0,09917366 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,07331463 0,09911878 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,07331463 0,09906396 ! epidermis morphogenesis GO:0048730 43 18 0,000 0,07331463 0,09900919 ! glycine metabolic process GO:0006544 30 18 0,000 0,07331463 0,09895449 ! glutamine metabolic process GO:0006541 29 18 0,000 0,07331463 0,09889985 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,07331463 0,09884527 ! DNA integration GO:0015074 32 18 0,000 0,07331463 0,09879075 ! negative regulation of protein catabolic process GO:0042177 42 18 0,000 0,07331463 0,09873629 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,07331463 0,09868189 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,07331463 0,09862755 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,07331463 0,09857327 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,07331463 0,09851905 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,07331463 0,09846489 GO:0046466|membrane lipid catabolic process, ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,07331463 0,09841079 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,07331463 0,09835674 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,07331463 0,09830276 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,07331463 0,09824884 ! detection of bacterium GO:0016045 22 18 0,000 0,07331463 0,09819497 ! nerve development GO:0021675 34 18 0,000 0,07331463 0,09814117 ! defense response to virus GO:0051607 43 18 0,000 0,07331463 0,09808742 ! microspike assembly GO:0030035 46 18 0,000 0,07331463 0,09803373 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,07331463 0,0979801 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 0,000 0,07331463 0,09792653 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,07722733 0,10309638 ! positive regulation of translation GO:0045727 31 19 0,000 0,07722733 0,10304007 ! negative regulation of defense response GO:0031348 27 19 0,000 0,07722733 0,10298383 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,07722733 0,10292764 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,07722733 0,10287152 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,07722733 0,10281546 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,07722733 0,10275946 ! inositol metabolic process GO:0006020 33 19 0,000 0,07722733 0,10270352 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,07722733 0,10264765 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,07722733 0,10259183 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,07722733 0,10253607 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,07722733 0,10248038 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,07722733 0,10242474 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 0,000 0,07722733 0,10236917 ! cerebral cortex development GO:0021987 40 19 0,000 0,07722733 0,10231365 ! pigmentation during development GO:0048066 42 19 0,000 0,07722733 0,1022582 ! heme metabolic process GO:0042168 40 19 0,000 0,07722733 0,1022028 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,07722733 0,10214747 ! response to fungus GO:0009620 26 19 0,000 0,07722733 0,10209219 ! peptide cross-linking GO:0018149 39 19 0,000 0,07722733 0,10203698 ! protein export from nucleus GO:0006611 40 19 0,000 0,07722733 0,10198182 ! heart process GO:0003015 32 19 0,000 0,07722733 0,10192673 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,07722733 0,10187169 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,07722733 0,10181672 ! visual learning GO:0008542 38 19 0,000 0,07722733 0,1017618 ! cellular pigmentation GO:0033059 37 19 0,000 0,07722733 0,10170694 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,07722733 0,10165214 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,07722733 0,1015974 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,07722733 0,10154272 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,07722733 0,1014881 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,07722733 0,10143353 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,07722733 0,10137903 ! cilium assembly GO:0042384 38 19 0,000 0,07722733 0,10132458 ! peptide hormone secretion GO:0030072 32 19 0,000 0,07722733 0,10127019 ! protein secretion GO:0009306 45 20 0,000 0,08112363 0,10632244 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,08112363 0,10626543 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,08112363 0,10620848 ! positive regulation of ossification GO:0045778 50 20 0,000 0,08112363 0,10615159 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,08112363 0,10609477 ! skin development GO:0043588 42 20 0,000 0,08112363 0,106038 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,08112363 0,1059813 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,08112363 0,10592465 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,08112363 0,10586807 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,08112363 0,10581154 ! bile acid metabolic process GO:0008206 34 20 0,000 0,08112363 0,10575508 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,08112363 0,10569868 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,08112363 0,10564234 GO:0032392|DNA geometric change, ! cellular response to unfolded protein GO:0034620 35 20 0,000 0,08112363 0,10558605 GO:0030968|endoplasmic reticulum unfolded protein response, ! actin filament bundle formation GO:0051017 47 20 0,000 0,08112363 0,10552983 ! body fluid secretion GO:0007589 33 20 0,000 0,08112363 0,10547367 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,08112363 0,10541757 ! peptide secretion GO:0002790 38 20 0,000 0,08112363 0,10536152 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,08112363 0,10530554 ! regulation of fatty acid metabolic process GO:0019217 45 20 0,000 0,08112363 0,10524961 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,08112363 0,10519375 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,08112363 0,10513794 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,08112363 0,1050822 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 0,000 0,08112363 0,10502651 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,08112363 0,10497088 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,08112363 0,10491531 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,08112363 0,1048598 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,08112363 0,10480435 ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,08112363 0,10474896 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,08112363 0,10469362 ! negative regulation of translation GO:0017148 32 20 0,000 0,08112363 0,10463834 ! regulation of cell killing GO:0031341 46 21 0,000 0,08500358 0,10958509 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,08500358 0,10952729 ! hormone secretion GO:0046879 39 21 0,000 0,08500358 0,10946956 ! cAMP metabolic process GO:0046058 41 21 0,000 0,08500358 0,10941188 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,08500358 0,10935426 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,08500358 0,10929671 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,08500358 0,10923922 ! ovarian follicle development GO:0001541 39 21 0,000 0,08500358 0,10918178 ! smooth muscle contraction GO:0006939 48 21 0,000 0,08500358 0,10912441 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,08500358 0,10906709 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,08500358 0,10900984 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,08500358 0,10895265 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,08500358 0,10889552 GO:0006692|prostanoid metabolic process, ! regulation of vasoconstriction GO:0019229 40 21 0,000 0,08500358 0,10883844 ! sensory perception of pain GO:0019233 33 21 0,000 0,08500358 0,10878143 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,08500358 0,10872448 ! diencephalon development GO:0021536 36 21 0,000 0,08500358 0,10866758 ! collagen fibril organization GO:0030199 62 21 0,000 0,08500358 0,10861075 ! negative regulation of intracellular transport GO:0032387 44 21 0,000 0,08500358 0,10855397 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 0,08500358 0,10849726 ! collagen catabolic process GO:0030574 29 21 0,000 0,08500358 0,1084406 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,08500358 0,108384 GO:0043450|alkene biosynthetic process, ! sperm-egg recognition GO:0035036 23 21 0,000 0,08500358 0,10832746 ! actin filament-based movement GO:0030048 47 21 0,000 0,08500358 0,10827098 ! positive regulation of protein catabolic process GO:0045732 44 22 0,000 0,08886726 0,11313325 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,08886726 0,11307433 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,08886726 0,11301547 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,08886726 0,11295667 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,08886726 0,11289793 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,08886726 0,11283925 ! microtubule-based transport GO:0010970 59 22 0,000 0,08886726 0,11278063 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,08886726 0,11272207 ! vacuolar transport GO:0007034 41 22 0,000 0,08886726 0,11266358 ! central nervous system neuron development GO:0021954 47 22 0,000 0,08886726 0,11260514 ! fucose metabolic process GO:0006004 44 22 0,000 0,08886726 0,11254677 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,08886726 0,11248845 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,08886726 0,1124302 ! stem cell differentiation GO:0048863 57 22 0,000 0,08886726 0,11237201 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,08886726 0,11231387 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 0,08886726 0,1122558 ! cytolysis GO:0019835 27 22 0,000 0,08886726 0,11219779 ! renal system process GO:0003014 42 22 0,000 0,08886726 0,11213983 ! vasodilation GO:0042311 40 22 0,000 0,08886726 0,11208194 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,08886726 0,11202411 ! detection of chemical stimulus GO:0009593 42 22 0,000 0,08886726 0,11196633 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,08886726 0,11190862 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,08886726 0,11185096 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,08886726 0,11179337 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,08886726 0,11173583 ! sarcomere organization GO:0045214 32 22 0,000 0,08886726 0,11167835 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,08886726 0,11162093 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,08886726 0,11156357 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,08886726 0,11150627 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,08886726 0,11144903 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,08886726 0,11139185 ! protein stabilization GO:0050821 41 22 0,000 0,08886726 0,11133473 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,09271473 0,11609538 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,09271473 0,11603591 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,09271473 0,11597649 ! glycerol metabolic process GO:0006071 40 23 0,000 0,09271473 0,11591714 ! viral genome replication GO:0019079 44 23 0,000 0,09271473 0,11585785 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,09271473 0,11579862 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,09271473 0,11573944 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,09271473 0,11568033 ! regeneration GO:0031099 42 23 0,000 0,09271473 0,11562128 ! axis specification GO:0009798 43 23 0,000 0,09271473 0,11556229 ! visual behavior GO:0007632 46 23 0,000 0,09271473 0,11550336 ! regulation of DNA recombination GO:0000018 51 23 0,000 0,09271473 0,11544449 ! response to ethanol GO:0045471 47 23 0,000 0,09271473 0,11538568 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,09271473 0,11532693 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,09271473 0,11526824 ! peroxisome organization GO:0007031 43 23 0,000 0,09271473 0,11520961 ! lysosome organization GO:0007040 47 23 0,000 0,09271473 0,11515104 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 0,09271473 0,11509253 ! vesicle targeting GO:0006903 49 23 0,000 0,09271473 0,11503407 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,09271473 0,11497568 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,09271473 0,11491735 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,09271473 0,11485907 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,09271473 0,11480086 ! DNA modification GO:0006304 36 23 0,000 0,09271473 0,1147427 ! fatty acid transport GO:0015908 47 23 0,000 0,09271473 0,1146846 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,09271473 0,11462656 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,09271473 0,11456858 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,09271473 0,11451066 ! hormone transport GO:0009914 41 23 0,000 0,09271473 0,1144528 ! cell-cell recognition GO:0009988 28 23 0,000 0,09271473 0,114395 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,09271473 0,11433725 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,09271473 0,11427956 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,09271473 0,11422193 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,09654607 0,11888208 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,09654607 0,11882219 GO:0016444|somatic cell DNA recombination, ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,09654607 0,11876236 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,09654607 0,11870259 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,09654607 0,11864288 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,09654607 0,11858323 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 0,09654607 0,11852364 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,09654607 0,11846411 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,09654607 0,11840464 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,09654607 0,11834523 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,09654607 0,11828588 GO:0042278|purine nucleoside metabolic process, ! positive regulation of cytoskeleton organization GO:0051495 52 24 0,000 0,09654607 0,11822659 ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,09654607 0,11816735 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,09654607 0,11810818 GO:0051693|actin filament capping, ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,09654607 0,11804907 GO:0002708|positive regulation of lymphocyte mediated immunity, ! leukotriene metabolic process GO:0006691 47 24 0,000 0,09654607 0,11799001 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,09654607 0,11793102 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,09654607 0,11787208 ! membrane depolarization GO:0051899 45 24 0,000 0,09654607 0,11781321 ! oogenesis GO:0048477 44 24 0,000 0,09654607 0,11775439 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,09654607 0,11769563 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,09654607 0,11763693 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,09654607 0,11757828 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,09654607 0,1175197 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,09654607 0,11746117 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,09654607 0,11740271 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,09654607 0,1173443 ! negative regulation of catabolic process GO:0009895 52 24 0,000 0,09654607 0,11728595 ! regulation of amine transport GO:0051952 41 24 0,000 0,09654607 0,11722765 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 0,000 0,09654607 0,11716942 ! myeloid leukocyte differentiation GO:0002573 46 25 0,000 0,10036133 0,12173919 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,10036133 0,12167877 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,10036133 0,12161841 ! phototransduction GO:0007602 37 25 0,000 0,10036133 0,12155812 ! keratinization GO:0031424 37 25 0,000 0,10036133 0,12149788 ! vacuole organization GO:0007033 49 25 0,000 0,10036133 0,1214377 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,10036133 0,12137759 ! receptor metabolic process GO:0043112 53 25 0,000 0,10036133 0,12131753 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,10036133 0,12125753 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,10036133 0,12119759 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,10036133 0,12113771 ! immunoglobulin production GO:0002377 62 25 0,000 0,10036133 0,12107789 GO:0002440|production of molecular mediator of immune response, ! leukocyte homeostasis GO:0001776 50 25 0,000 0,10036133 0,12101813 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,10036133 0,12095842 ! liver development GO:0001889 55 25 0,000 0,10036133 0,12089878 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,10416058 0,12541366 ! initiation of viral infection GO:0019059 60 26 0,000 0,10416058 0,12535188 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,10416058 0,12529016 ! molting cycle process GO:0022404 52 26 0,000 0,10416058 0,1252285 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,10416058 0,1251669 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,10416058 0,12510536 GO:0006479|protein amino acid methylation, ! regulation of transcription factor import into nucleus GO:0042990 58 26 0,000 0,10416058 0,12504389 ! microtubule organizing center organization GO:0031023 42 26 0,000 0,10416058 0,12498247 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,10416058 0,12492111 ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,10416058 0,12485982 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,10416058 0,12479858 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,10416058 0,12473741 ! regulation of cellular ketone metabolic process GO:0010565 51 26 0,000 0,10416058 0,12467629 ! osteoblast differentiation GO:0001649 63 26 0,000 0,10416058 0,12461523 ! coenzyme catabolic process GO:0009109 42 26 0,000 0,10416058 0,12455424 ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,10416058 0,1244933 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,10416058 0,12443242 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,10416058 0,12437161 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,10416058 0,12431085 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,10416058 0,12425015 ! regulation of osteoblast differentiation GO:0045667 68 26 0,000 0,10416058 0,12418951 ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,10416058 0,12412893 ! blastocyst development GO:0001824 50 26 0,000 0,10416058 0,12406841 ! telomere organization GO:0032200 46 26 0,000 0,10416058 0,12400795 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,10416058 0,12394754 ! alditol metabolic process GO:0019400 44 26 0,000 0,10416058 0,1238872 ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,10416058 0,12382691 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,10416058 0,12376669 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,1079439 0,12819978 ! embryonic pattern specification GO:0009880 49 27 0,000 0,1079439 0,12813749 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,1079439 0,12807526 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,1079439 0,12801308 ! positive regulation of cell projection organization GO:0031346 66 27 0,000 0,1079439 0,12795097 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,1079439 0,12788892 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,1079439 0,12782693 ! iron ion transport GO:0006826 65 27 0,000 0,1079439 0,127765 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,1079439 0,12770313 ! superoxide metabolic process GO:0006801 41 27 0,000 0,1079439 0,12764131 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,1079439 0,12757956 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,1079439 0,12751787 ! response to toxin GO:0009636 49 27 0,000 0,1079439 0,12745624 ! cellular response to oxidative stress GO:0034599 43 27 0,000 0,1079439 0,12739466 ! leukocyte proliferation GO:0070661 59 27 0,000 0,1079439 0,12733315 GO:0032943|mononuclear cell proliferation, ! neuron fate commitment GO:0048663 52 28 0,000 0,11171135 0,13171372 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,11171135 0,13165018 ! vesicle docking GO:0048278 55 28 0,000 0,11171135 0,13158671 ! circadian rhythm GO:0007623 56 28 0,000 0,11171135 0,13152329 ! dendrite development GO:0016358 67 28 0,000 0,11171135 0,13145994 ! fat cell differentiation GO:0045444 57 28 0,000 0,11171135 0,13139664 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,11171135 0,13133341 ! sperm motility GO:0030317 37 28 0,000 0,11171135 0,13127024 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,11171135 0,13120713 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,11171135 0,13114408 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,11171135 0,13108109 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,11171135 0,13101816 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,11171135 0,13095529 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,11171135 0,13089248 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,11171135 0,13082973 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,11171135 0,13076705 ! lipid oxidation GO:0034440 48 28 0,000 0,11171135 0,13070442 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,11171135 0,13064185 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,11171135 0,13057934 ! translational initiation GO:0006413 66 29 0,000 0,11546299 0,13490009 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,11546299 0,13483561 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,11546299 0,13477118 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! autophagy GO:0006914 47 29 0,000 0,11546299 0,13470682 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,11546299 0,13464252 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,11546299 0,13457829 ! synaptogenesis GO:0007416 46 29 0,000 0,11546299 0,13451411 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,11546299 0,13444999 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,11546299 0,13438594 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,11546299 0,13432195 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,11919889 0,13860204 ! phenol metabolic process GO:0018958 56 30 0,000 0,11919889 0,13853611 ! negative regulation of protein complex assembly GO:0031333 68 30 0,000 0,11919889 0,13847023 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,11919889 0,13840442 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,11919889 0,13833867 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,11919889 0,13827298 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,11919889 0,13820735 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,11919889 0,13814179 ! acute-phase response GO:0006953 50 30 0,000 0,11919889 0,13807629 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,11919889 0,13801085 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,11919889 0,13794547 ! myofibril assembly GO:0030239 50 30 0,000 0,11919889 0,13788016 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 72 30 0,000 0,11919889 0,13781491 ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,11919889 0,13774971 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,11919889 0,13768458 ! cell fate determination GO:0001709 64 30 0,000 0,11919889 0,13761952 ! positive regulation of multicellular organism growth GO:0040018 55 30 0,000 0,11919889 0,13755451 ! phospholipid transport GO:0015914 65 30 0,000 0,11919889 0,13748956 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,11919889 0,13742468 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,11919889 0,13735986 GO:0046496|nicotinamide nucleotide metabolic process, ! alkaloid metabolic process GO:0009820 57 31 0,000 0,12291912 0,14158011 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,12291912 0,14151339 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,12291912 0,14144673 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,12291912 0,14138014 ! regulation of innate immune response GO:0045088 57 31 0,000 0,12291912 0,14131361 ! ovulation cycle process GO:0022602 55 31 0,000 0,12291912 0,14124714 ! peptide transport GO:0015833 60 31 0,000 0,12291912 0,14118073 ! male gonad development GO:0008584 56 31 0,000 0,12291912 0,14111439 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,12291912 0,1410481 ! detection of light stimulus GO:0009583 44 31 0,000 0,12291912 0,14098188 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 0,000 0,12291912 0,14091573 ! natural killer cell activation GO:0030101 50 31 0,000 0,12291912 0,14084963 ! cofactor catabolic process GO:0051187 54 31 0,000 0,12291912 0,1407836 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,12291912 0,14071762 ! response to heat GO:0009408 54 31 0,000 0,12291912 0,14065171 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,12291912 0,14058587 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,12662374 0,14475517 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,12662374 0,14468746 ! collagen metabolic process GO:0032963 49 32 0,000 0,12662374 0,14461982 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,12662374 0,14455224 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,12662374 0,14448472 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,12662374 0,14441727 ! regulation of protein import into nucleus GO:0042306 69 32 0,000 0,12662374 0,14434988 ! muscle cell development GO:0055001 52 32 0,000 0,12662374 0,14428255 ! mesoderm formation GO:0001707 73 32 0,000 0,12662374 0,14421529 ! ovulation cycle GO:0042698 57 32 0,000 0,12662374 0,14414809 ! BMP signaling pathway GO:0030509 71 32 0,000 0,12662374 0,14408095 ! hindbrain development GO:0030902 65 32 0,000 0,12662374 0,14401387 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,12662374 0,14394686 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,12662374 0,1438799 ! gene silencing GO:0016458 71 32 0,000 0,12662374 0,14381302 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,13031281 0,14793411 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,13031281 0,1478654 GO:0055092|sterol homeostasis, ! pigment biosynthetic process GO:0046148 73 33 0,000 0,13031281 0,14779675 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,13031281 0,14772817 ! triglyceride metabolic process GO:0006641 46 33 0,000 0,13031281 0,14765965 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,13031281 0,14759119 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,13031281 0,1475228 ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,13031281 0,14745447 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,13031281 0,14738621 ! negative regulation of protein transport GO:0051224 74 33 0,000 0,13031281 0,147318 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,13031281 0,14724986 ! glial cell differentiation GO:0010001 67 34 0,000 0,13398641 0,15133093 ! post-embryonic development GO:0009791 76 34 0,000 0,13398641 0,151261 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,13398641 0,15119113 ! cholesterol transport GO:0030301 62 34 0,000 0,13398641 0,15112133 ! spliceosome assembly GO:0000245 75 34 0,000 0,13398641 0,15105159 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,13398641 0,15098192 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,13398641 0,15091231 ! formation of primary germ layer GO:0001704 76 34 0,000 0,13398641 0,15084277 ! cell fate specification GO:0001708 56 34 0,000 0,13398641 0,15077329 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,13398641 0,15070387 ! adult locomotory behavior GO:0008344 62 34 0,000 0,13398641 0,15063452 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,13764459 0,15467605 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,13764459 0,15460494 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,13764459 0,15453389 ! membrane docking GO:0022406 69 35 0,000 0,13764459 0,1544629 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,13764459 0,15439198 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,13764459 0,15432113 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,13764459 0,15425034 ! ceramide metabolic process GO:0006672 72 35 0,000 0,13764459 0,15417961 ! sterol transport GO:0015918 63 35 0,000 0,13764459 0,15410896 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,13764459 0,15403836 ! placenta development GO:0001890 53 35 0,000 0,13764459 0,15396783 ! vesicle localization GO:0051648 70 35 0,000 0,13764459 0,15389736 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,14128742 0,15789807 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,14128742 0,15782587 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,14128742 0,15775374 ! positive regulation of cell development GO:0010720 85 36 0,000 0,14128742 0,15768167 ! protein targeting to membrane GO:0006612 75 36 0,000 0,14128742 0,15760967 ! aerobic respiration GO:0009060 56 36 0,000 0,14128742 0,15753774 ! cytokine production GO:0001816 68 36 0,000 0,14128742 0,15746587 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,14128742 0,15739406 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 0,000 0,14491497 0,16136156 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,14491497 0,16128805 ! odontogenesis GO:0042476 74 37 0,000 0,14491497 0,1612146 ! actomyosin structure organization GO:0031032 68 37 0,000 0,14491497 0,16114123 ! maintenance of protein location in cell GO:0032507 89 37 0,000 0,14491497 0,16106791 ! female gonad development GO:0008585 71 37 0,000 0,14491497 0,16099467 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,14491497 0,16092149 ! regulation of microtubule-based process GO:0032886 86 37 0,000 0,14491497 0,16084837 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,14852729 0,164783 ! organic anion transport GO:0015711 82 38 0,000 0,14852729 0,16470821 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,14852729 0,16463347 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,14852729 0,16455881 ! neutral lipid metabolic process GO:0006638 54 38 0,000 0,14852729 0,16448421 GO:0006639|acylglycerol metabolic process, ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,14852729 0,16440969 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,14852729 0,16433523 ! spermatid development GO:0007286 69 38 0,000 0,14852729 0,16426083 ! pigment metabolic process GO:0042440 87 38 0,000 0,14852729 0,16418651 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,15212446 0,16808686 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,15212446 0,16801087 ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,15212446 0,16793495 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,15212446 0,1678591 ! erythrocyte homeostasis GO:0034101 75 39 0,000 0,15212446 0,16778332 ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,15212446 0,1677076 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,15570653 0,17157918 GO:0006956|complement activation, ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,15570653 0,17150182 ! learning GO:0007612 82 40 0,000 0,15570653 0,17142453 ! lipid homeostasis GO:0055088 75 40 0,000 0,15570653 0,17134732 ! mismatch repair GO:0006298 58 40 0,000 0,15570653 0,17127017 ! glycerol ether metabolic process GO:0006662 57 40 0,000 0,15570653 0,17119309 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,15570653 0,17111608 ! RNA export from nucleus GO:0006405 61 41 0,000 0,15927356 0,17495742 ! mRNA catabolic process GO:0006402 79 41 0,000 0,15927356 0,17487879 ! establishment or maintenance of cell polarity GO:0007163 96 41 0,000 0,15927356 0,17480023 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,15927356 0,17472174 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,15927356 0,17464332 ! gliogenesis GO:0042063 91 41 0,000 0,15927356 0,17456497 ! feeding behavior GO:0007631 69 41 0,000 0,15927356 0,17448669 ! multicellular organismal metabolic process GO:0044236 64 41 0,000 0,15927356 0,17440848 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,15927356 0,17433034 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 95 41 0,000 0,15927356 0,17425227 ! spermatid differentiation GO:0048515 73 41 0,000 0,15927356 0,17417427 ! RNA modification GO:0009451 64 41 0,000 0,15927356 0,17409633 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,16282563 0,17789938 ! organic ether metabolic process GO:0018904 59 42 0,000 0,16282563 0,17781985 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,16282563 0,17774039 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,16282563 0,17766101 ! dorsal/ventral pattern formation GO:0009953 75 42 0,000 0,16282563 0,1775817 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,16282563 0,17750246 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,16636278 0,18127756 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,16636278 0,18119674 ! regulation of tube size GO:0035150 76 43 0,000 0,16636278 0,18111599 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,16636278 0,18103531 ! glucose transport GO:0015758 66 43 0,000 0,16636278 0,18095471 ! striated muscle cell differentiation GO:0051146 91 43 0,000 0,16636278 0,18087418 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,16636278 0,18079372 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,16636278 0,18071333 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,16636278 0,18063301 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,16636278 0,18055277 ! ion transmembrane transport GO:0034220 79 43 0,000 0,16636278 0,18047259 ! regulation of myeloid cell differentiation GO:0045637 105 43 0,000 0,16636278 0,18039249 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,16988509 0,18413012 ! negative regulation of protein complex disassembly GO:0043242 113 44 0,000 0,16988509 0,18404846 ! hexose transport GO:0008645 68 44 0,000 0,16988509 0,18396688 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 0,000 0,16988509 0,18388537 ! striated muscle contraction GO:0006941 85 44 0,000 0,16988509 0,18380394 ! phagocytosis GO:0006909 105 44 0,000 0,16988509 0,18372257 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,16988509 0,18364128 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,17339262 0,18734992 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,17339262 0,1872671 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! keratinocyte differentiation GO:0030216 81 45 0,000 0,17339262 0,18718435 ! biopolymer methylation GO:0043414 91 45 0,000 0,17339262 0,18710167 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,17339262 0,18701906 ! female gamete generation GO:0007292 71 45 0,000 0,17339262 0,18693653 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,17339262 0,18685407 ! polyol metabolic process GO:0019751 77 45 0,000 0,17339262 0,18677168 ! maintenance of location in cell GO:0051651 101 45 0,000 0,17339262 0,18668937 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,17688543 0,19036612 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,17688543 0,1902823 ! glycolysis GO:0006096 71 46 0,000 0,17688543 0,19019855 ! negative regulation of cell migration GO:0030336 122 46 0,000 0,17688543 0,19011487 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,17688543 0,19003127 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,17688543 0,18994774 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,18036357 0,19359763 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,18382712 0,19722866 ! regulation of JAK-STAT cascade GO:0046425 76 48 0,000 0,18382712 0,19714208 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 0,000 0,18382712 0,19705557 ! endosome transport GO:0016197 127 48 0,000 0,18382712 0,19696914 ! male sex differentiation GO:0046661 93 48 0,000 0,18382712 0,19688279 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,18382712 0,19679652 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,18382712 0,19671031 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,18382712 0,19662419 ! methylation GO:0032259 97 48 0,000 0,18382712 0,19653814 ! response to calcium ion GO:0051592 94 49 0,000 0,18727612 0,20013805 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,18727612 0,20005053 ! JNK cascade GO:0007254 106 49 0,000 0,18727612 0,1999631 ! protein homooligomerization GO:0051260 84 49 0,000 0,18727612 0,19987574 ! regulation of ion transport GO:0043269 86 50 0,000 0,19071065 0,20345246 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,19071065 0,20336365 ! regulation of ossification GO:0030278 123 50 0,000 0,19071065 0,20327492 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,19071065 0,20318627 GO:0019724|B cell mediated immunity, ! regulation of gene expression, epigenetic GO:0040029 116 50 0,000 0,19071065 0,2030977 ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,19071065 0,2030092 ! epidermal cell differentiation GO:0009913 87 50 0,000 0,19071065 0,20292079 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,19071065 0,20283244 ! regulation of cell projection organization GO:0031344 135 51 0,000 0,19413076 0,20638009 ! viral infectious cycle GO:0019058 104 51 0,000 0,19413076 0,20629032 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,19413076 0,20620063 ! response to temperature stimulus GO:0009266 84 51 0,000 0,19413076 0,20611102 ! response to estrogen stimulus GO:0043627 98 52 0,000 0,19753652 0,20963584 ! Notch signaling pathway GO:0007219 111 52 0,000 0,19753652 0,20954481 ! regulation of protein complex disassembly GO:0043244 127 52 0,000 0,19753652 0,20945387 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,19753652 0,209363 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,19753652 0,20927221 ! excretion GO:0007588 87 52 0,000 0,19753652 0,20918149 ! DNA-dependent DNA replication GO:0006261 82 52 0,000 0,19753652 0,20909086 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,19753652 0,20900031 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,19753652 0,20890983 ! amino acid activation GO:0043038 98 52 0,000 0,19753652 0,20881943 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,20092797 0,21231273 ! inner ear development GO:0048839 89 53 0,000 0,20092797 0,21222094 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,20092797 0,21212923 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,20092797 0,2120376 ! vesicle organization GO:0016050 127 53 0,000 0,20092797 0,21194604 ! regulation of translational initiation GO:0006446 87 54 0,000 0,20430519 0,21541544 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,20430519 0,21532251 ! RNA catabolic process GO:0006401 103 55 0,000 0,20766823 0,21877252 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,20766823 0,21867822 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,20766823 0,21858401 ! cell recognition GO:0008037 98 55 0,000 0,20766823 0,21848987 ! regulation of multicellular organism growth GO:0040014 90 55 0,000 0,20766823 0,21839581 ! regulation of protein polymerization GO:0032271 117 55 0,000 0,20766823 0,21830184 ! negative regulation of cell motion GO:0051271 142 55 0,000 0,20766823 0,21820795 ! negative regulation of cytoskeleton organization GO:0051494 139 56 0,000 0,21101714 0,22163151 ! glucose catabolic process GO:0006007 88 56 0,000 0,21101714 0,22153626 ! RNA elongation GO:0006354 90 56 0,000 0,21101714 0,2214411 ! chloride transport GO:0006821 102 57 0,000 0,214352 0,22484411 ! regulation of actin filament length GO:0030832 118 58 0,000 0,21767286 0,22822952 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,21767286 0,22813161 ! gastrulation GO:0007369 122 58 0,000 0,21767286 0,22803379 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,21767286 0,22793604 ! maintenance of location GO:0051235 124 58 0,000 0,21767286 0,22783839 ! nuclear export GO:0051168 110 59 0,000 0,22097977 0,23120068 ! regulation of endocytosis GO:0030100 104 60 0,000 0,2242728 0,23454556 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,2242728 0,2344452 ! adult behavior GO:0030534 104 60 0,000 0,2242728 0,23434493 ! regulation of cellular component size GO:0032535 125 61 0,000 0,22755199 0,23766974 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,22755199 0,23756817 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,22755199 0,23746669 ! cytokine-mediated signaling pathway GO:0019221 112 61 0,000 0,22755199 0,2373653 ! proton transport GO:0015992 117 61 0,000 0,22755199 0,23726399 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,23081742 0,24056611 ! tRNA processing GO:0008033 102 62 0,000 0,23081742 0,24046352 ! regulation of protein complex assembly GO:0043254 132 63 0,000 0,23406914 0,24374719 ! mesoderm development GO:0007498 128 63 0,000 0,23406914 0,24364333 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,23406914 0,24353957 ! hydrogen transport GO:0006818 121 64 0,000 0,2373072 0,24680353 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,24053166 0,25005057 ! multicellular organism reproduction GO:0032504 123 65 0,000 0,24053166 0,24994421 GO:0048609|reproductive process in a multicellular organism, ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,24053166 0,24983795 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,24053166 0,24973177 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,24374258 0,252958 ! regulation of lipid metabolic process GO:0019216 132 66 0,000 0,24374258 0,25285059 ! gonad development GO:0008406 115 66 0,000 0,24374258 0,25274326 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,24694002 0,25595013 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,24694002 0,25584159 ! myeloid cell differentiation GO:0030099 126 67 0,000 0,24694002 0,25573313 ! regulation of cellular response to stress GO:0080135 142 68 0,000 0,25012402 0,25892076 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,25012402 0,25881109 ! hexose catabolic process GO:0019320 113 68 0,000 0,25012402 0,25870152 ! extracellular matrix organization GO:0030198 146 68 0,000 0,25012402 0,25859204 ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,25012402 0,25848265 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 0,000 0,25012402 0,25837336 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 0,000 0,25329466 0,26153797 ! homeostasis of number of cells GO:0048872 131 69 0,000 0,25329466 0,26142748 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,25329466 0,26131708 ! cell redox homeostasis GO:0045454 114 70 0,000 0,25645197 0,26446272 ! germ cell development GO:0007281 133 70 0,000 0,25645197 0,26435113 ! activation of immune response GO:0002253 120 70 0,000 0,25645197 0,26423963 ! protein maturation by peptide bond cleavage GO:0051605 118 70 0,000 0,25645197 0,26412823 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,25959603 0,26725373 ! cAMP-mediated signaling GO:0019933 124 71 0,000 0,25959603 0,26714115 ! carbohydrate transport GO:0008643 114 72 0,000 0,26272688 0,27024916 ! actin filament organization GO:0007015 167 72 0,000 0,26272688 0,27013542 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 0,000 0,26272688 0,27002178 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 0,000 0,26272688 0,26990823 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,26272688 0,26979477 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,26272688 0,26968141 ! regulation of MAPKKK cascade GO:0043408 157 72 0,000 0,26272688 0,26956815 ! humoral immune response GO:0006959 115 73 0,000 0,26584458 0,27265252 ! acute inflammatory response GO:0002526 118 74 0,000 0,26894918 0,27572087 ! amino acid transport GO:0006865 148 74 0,000 0,26894918 0,27560522 ! transition metal ion transport GO:0000041 143 75 0,000 0,27204074 0,2786564 ! rhythmic process GO:0048511 142 75 0,000 0,27204074 0,27853961 ! regulation of actin cytoskeleton organization GO:0032956 167 76 0,000 0,27511931 0,28157372 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,27511931 0,28145581 ! regulation of blood pressure GO:0008217 134 76 0,000 0,27511931 0,281338 ! amine catabolic process GO:0009310 136 77 0,000 0,27818495 0,2843539 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,27818495 0,28423498 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,27818495 0,28411615 ! positive regulation of ligase activity GO:0051351 130 77 0,000 0,27818495 0,28399742 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,27818495 0,28387879 ! antigen processing and presentation GO:0019882 117 78 0,000 0,28123771 0,28687421 ! regulation of actin filament-based process GO:0032970 170 79 0,000 0,28427764 0,28985404 ! steroid biosynthetic process GO:0006694 146 79 0,000 0,28427764 0,28973312 ! response to steroid hormone stimulus GO:0048545 147 79 0,000 0,28427764 0,2896123 ! regulation of synaptic transmission GO:0050804 159 79 0,000 0,28427764 0,28949157 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 0,000 0,28730481 0,29245235 ! muscle cell differentiation GO:0042692 178 81 0,000 0,29031925 0,29539772 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 0,000 0,29031925 0,29527474 ! regulation of adenylate cyclase activity GO:0045761 165 83 0,000 0,2963102 0,30124254 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,2963102 0,30111723 ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,2963102 0,30099202 ! inorganic anion transport GO:0015698 156 83 0,000 0,2963102 0,30086692 ! response to metal ion GO:0010038 158 84 0,000 0,29928681 0,30376305 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,30225091 0,30664409 ! regulation of cyclase activity GO:0031279 168 85 0,000 0,30225091 0,3065168 ! regulation of transmission of nerve impulse GO:0051969 167 85 0,000 0,30225091 0,30638961 ! regulation of cAMP biosynthetic process GO:0030817 173 86 0,000 0,30520255 0,30925335 ! regulation of lyase activity GO:0051339 169 86 0,000 0,30520255 0,30912514 ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,30814179 0,31197281 ! alcohol catabolic process GO:0046164 142 87 0,000 0,30814179 0,31184358 ! nucleosome assembly GO:0006334 126 87 0,000 0,30814179 0,31171445 ! cellular respiration GO:0045333 143 88 0,000 0,31106868 0,31454503 ! amine biosynthetic process GO:0009309 146 88 0,000 0,31106868 0,31441489 ! sensory perception of smell GO:0007608 117 88 0,000 0,31106868 0,31428486 ! chromatin assembly GO:0031497 128 88 0,000 0,31106868 0,31415494 ! one-carbon metabolic process GO:0006730 167 88 0,000 0,31106868 0,31402512 ! regulation of cAMP metabolic process GO:0030814 182 89 0,000 0,31398327 0,31683649 ! cellular defense response GO:0006968 123 89 0,000 0,31398327 0,31670567 ! regulation of neurological system process GO:0031644 175 89 0,000 0,31398327 0,31657496 ! response to inorganic substance GO:0010035 173 90 0,000 0,31688561 0,31936945 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,31688561 0,31923775 ! response to unfolded protein GO:0006986 139 90 0,000 0,31688561 0,31910616 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 0,000 0,31977576 0,32188388 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! defense response to bacterium GO:0042742 112 91 0,000 0,31977576 0,32175131 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,32265375 0,32451343 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 0,000 0,32551966 0,32726112 GO:0010498|proteasomal protein catabolic process, ! amine transport GO:0015837 181 93 0,000 0,32551966 0,3271265 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,32837351 0,32985875 ! female pregnancy GO:0007565 166 94 0,000 0,32837351 0,32972318 ! sterol metabolic process GO:0016125 166 94 0,000 0,32837351 0,32958771 ! nucleosome organization GO:0034728 143 95 0,000 0,33121537 0,33230355 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 0,000 0,33121537 0,33216714 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,33121537 0,33203084 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,33121537 0,33189465 ! response to protein stimulus GO:0051789 158 96 0,000 0,33404529 0,33459313 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,33686331 0,33727749 ! regulation of nucleotide metabolic process GO:0006140 197 98 0,000 0,33966949 0,33994779 ! mRNA transport GO:0051028 185 100 0,000 0,3452465 0,34538788 ! positive regulation of immune response GO:0050778 175 100 0,000 0,3452465 0,3452465