pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6707-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! apoptotic mitochondrial changes GO:0008637 42 20 5,000 3,268E-09 7,984E-06 ! urogenital system development GO:0001655 149 69 7,000 2,328E-08 2,844E-05 ! release of cytochrome c from mitochondria GO:0001836 31 14 4,000 2,618E-08 2,132E-05 ! metanephros development GO:0001656 81 32 5,000 7,138E-08 4,359E-05 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 3,000 1,413E-07 6,902E-05 ! kidney development GO:0001822 133 60 6,000 1,717E-07 6,993E-05 ! insulin receptor signaling pathway GO:0008286 66 27 4,000 9,825E-07 3,429E-04 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 3,000 1,956E-06 5,974E-04 GO:0060675|ureteric bud morphogenesis, ! response to gamma radiation GO:0010332 30 14 3,000 1,956E-06 5,31E-04 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 2,000 3,048E-06 7,446E-04 ! stem cell division GO:0017145 11 5 2,000 3,048E-06 6,769E-04 GO:0048103|somatic stem cell division, ! response to peptide hormone stimulus GO:0043434 129 64 5,000 4,927E-06 1,003E-03 ! cellular response to insulin stimulus GO:0032869 85 38 4,000 5,748E-06 1,08E-03 ! neural nucleus development GO:0048857 19 6 2,000 6,065E-06 1,058E-03 ! negative regulation of neuroblast proliferation GO:0007406 25 6 2,000 6,065E-06 9,878E-04 ! B cell lineage commitment GO:0002326 21 7 2,000 1,056E-05 1,612E-03 ! T cell lineage commitment GO:0002360 16 7 2,000 1,056E-05 1,518E-03 ! induction of apoptosis by intracellular signals GO:0008629 95 45 4,000 1,346E-05 1,827E-03 ! ureteric bud development GO:0001657 50 22 3,000 1,37E-05 1,761E-03 ! cell aging GO:0007569 48 22 3,000 1,37E-05 1,673E-03 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 4,000 1,502E-05 1,747E-03 ! regulation of gene-specific transcription GO:0032583 102 46 4,000 1,502E-05 1,668E-03 ! regulation of cell-matrix adhesion GO:0001952 81 23 3,000 1,649E-05 1,752E-03 GO:0010810|regulation of cell-substrate adhesion, ! response to insulin stimulus GO:0032868 98 47 4,000 1,672E-05 1,701E-03 ! regulation of T cell differentiation in the thymus GO:0033081 14 8 2,000 1,681E-05 1,643E-03 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 3,000 2,331E-05 2,191E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 2,000 2,509E-05 2,27E-03 ! cellular response to hormone stimulus GO:0032870 182 85 5,000 2,553E-05 2,227E-03 ! negative regulation of cell development GO:0010721 83 26 3,000 2,741E-05 2,309E-03 GO:0050768|negative regulation of neurogenesis, ! mitochondrion organization GO:0007005 159 87 5,000 2,914E-05 2,373E-03 ! positive regulation of growth GO:0045927 96 53 4,000 3,025E-05 2,384E-03 ! regulation of smooth muscle cell migration GO:0014910 27 10 2,000 3,567E-05 2,723E-03 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 2,000 3,567E-05 2,64E-03 ! regulation of gliogenesis GO:0014013 23 10 2,000 3,567E-05 2,563E-03 GO:0045685|regulation of glial cell differentiation, ! response to UV GO:0009411 120 55 4,000 3,627E-05 2,532E-03 ! gland development GO:0048732 220 91 5,000 3,761E-05 2,552E-03 ! aging GO:0007568 112 58 4,000 4,699E-05 3,103E-03 ! oocyte development GO:0048599 20 11 2,000 4,879E-05 3,137E-03 ! regulation of DNA metabolic process GO:0051052 188 97 5,000 5,391E-05 3,377E-03 ! focal adhesion formation GO:0048041 37 12 2,000 6,473E-05 3,954E-03 ! autonomic nervous system development GO:0048483 24 12 2,000 6,473E-05 3,857E-03 ! oocyte differentiation GO:0009994 21 12 2,000 6,473E-05 3,765E-03 ! negative regulation of mast cell proliferation GO:0070667 24 12 2,000 6,473E-05 3,678E-03 GO:0042130|negative regulation of T cell proliferation, ! response to ionizing radiation GO:0010212 74 33 3,000 7,227E-05 4,013E-03 ! double-strand break repair via homologous recombination GO:0000724 19 13 2,000 8,373E-05 4,546E-03 GO:0000725|recombinational repair, ! response to X-ray GO:0010165 28 13 2,000 8,373E-05 4,447E-03 ! germ cell development GO:0007281 133 70 4,000 1,162E-04 6,04E-03 ! regulation of protein stability GO:0031647 77 38 3,000 1,27E-04 6,461E-03 ! regulation of caspase activity GO:0043281 136 74 4,000 1,513E-04 7,543E-03 ! reproductive structure development GO:0048608 131 75 4,000 1,612E-04 7,877E-03 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 2,000 1,615E-04 7,736E-03 ! negative regulation of leukocyte proliferation GO:0070664 32 16 2,000 1,615E-04 7,588E-03 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 2,000 1,615E-04 7,444E-03 ! regulation of endopeptidase activity GO:0052548 141 77 4,000 1,825E-04 8,258E-03 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 2,000 1,951E-04 8,667E-03 ! protein oligomerization GO:0051259 149 79 4,000 2,059E-04 8,984E-03 ! double-strand break repair GO:0006302 85 44 3,000 2,262E-04 9,693E-03 ! cell-substrate junction assembly GO:0007044 56 18 2,000 2,33E-04 9,813E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 2,000 2,33E-04 9,647E-03 ! regulation of peptidase activity GO:0052547 150 82 4,000 2,452E-04 9,985E-03 ! branching morphogenesis of a tube GO:0048754 102 45 3,000 2,469E-04 9,888E-03 ! regulation of epithelial cell proliferation GO:0050678 122 45 3,000 2,469E-04 9,729E-03 ! negative regulation of cell migration GO:0030336 122 46 3,000 2,69E-04 0,0104307 ! pigmentation GO:0043473 103 46 3,000 2,69E-04 0,01026772 ! positive regulation of cell cycle GO:0045787 96 48 3,000 3,174E-04 0,0119276 ! response to alkaloid GO:0043279 38 20 2,000 3,222E-04 0,01192804 ! negative regulation of T cell activation GO:0050868 41 20 2,000 3,222E-04 0,01175001 ! activation of caspase activity GO:0006919 95 50 3,000 3,717E-04 0,01335211 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 2,000 3,741E-04 0,01324451 ! cell structure disassembly during apoptosis GO:0006921 32 21 2,000 3,741E-04 0,0130553 ! negative regulation of intracellular transport GO:0032387 44 21 2,000 3,741E-04 0,01287142 ! regulation of cell adhesion GO:0030155 241 92 4,000 4,184E-04 0,01419706 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 2,000 4,31E-04 0,01442304 ! apoptotic nuclear changes GO:0030262 34 22 2,000 4,31E-04 0,01422814 ! response to estrogen stimulus GO:0043627 98 52 3,000 4,323E-04 0,0140809 ! morphogenesis of a branching structure GO:0001763 116 52 3,000 4,323E-04 0,01389563 ! positive regulation of MAP kinase activity GO:0043406 174 93 4,000 4,398E-04 0,01395278 ! positive regulation of muscle development GO:0048636 15 5 1,000 4,517E-04 0,01414771 GO:0045844|positive regulation of striated muscle development, ! 2-oxoglutarate metabolic process GO:0006103 10 5 1,000 4,517E-04 0,01396862 ! positive regulation of glycolysis GO:0045821 13 5 1,000 4,517E-04 0,01379401 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 1,000 4,517E-04 0,01362372 ! smooth muscle tissue development GO:0048745 32 5 1,000 4,517E-04 0,01345757 ! negative regulation of survival gene product expression GO:0008634 9 5 1,000 4,517E-04 0,01329544 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 1,000 4,517E-04 0,01313716 ! microvillus organization GO:0032528 8 5 1,000 4,517E-04 0,0129826 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 12 5 1,000 4,517E-04 0,01283164 ! morphogenesis of an epithelial sheet GO:0002011 11 5 1,000 4,517E-04 0,01268415 ! regulation of phospholipase A2 activity GO:0032429 15 5 1,000 4,517E-04 0,01254001 ! peptidyl-threonine phosphorylation GO:0018107 20 5 1,000 4,517E-04 0,01239911 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 1,000 4,517E-04 0,01226135 ! homeostasis of number of cells within a tissue GO:0048873 12 5 1,000 4,517E-04 0,01212661 ! meiotic chromosome segregation GO:0045132 10 5 1,000 4,517E-04 0,01199479 ! forebrain morphogenesis GO:0048853 13 5 1,000 4,517E-04 0,01186582 ! response to cadmium ion GO:0046686 7 5 1,000 4,517E-04 0,01173959 ! mitotic recombination GO:0006312 9 5 1,000 4,517E-04 0,01161601 ! B cell homeostasis GO:0001782 13 5 1,000 4,517E-04 0,01149501 ! inner cell mass cell proliferation GO:0001833 5 5 1,000 4,517E-04 0,01137651 ! regulation of mitochondrial depolarization GO:0051900 14 5 1,000 4,517E-04 0,01126042 ! hemopoietic progenitor cell differentiation GO:0002244 14 5 1,000 4,517E-04 0,01114668 ! protein insertion into membrane GO:0051205 17 5 1,000 4,517E-04 0,01103521 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 1,000 4,517E-04 0,01092595 GO:0022011|myelination in the peripheral nervous system, ! phospholipid scrambling GO:0017121 8 5 1,000 4,517E-04 0,01081883 ! regulation of neuron apoptosis GO:0043523 117 53 3,000 4,651E-04 0,0110315 ! synapse organization GO:0050808 102 53 3,000 4,651E-04 0,01092542 ! activation of pro-apoptotic gene products GO:0008633 51 23 2,000 4,932E-04 0,011474 ! epithelial tube morphogenesis GO:0060562 114 54 3,000 4,997E-04 0,01151569 ! sex differentiation GO:0007548 171 96 4,000 5,088E-04 0,0116166 ! transcription initiation GO:0006352 171 97 4,000 5,335E-04 0,01206826 ! negative regulation of cell motion GO:0051271 142 55 3,000 5,36E-04 0,01201332 ! interphase of mitotic cell cycle GO:0051329 224 98 4,000 5,591E-04 0,0124177 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 2,000 5,608E-04 0,01234242 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 2,000 5,608E-04 0,01223222 ! sex determination GO:0007530 48 24 2,000 5,608E-04 0,01212397 ! oogenesis GO:0048477 44 24 2,000 5,608E-04 0,01201762 ! regulation of DNA replication GO:0006275 105 56 3,000 5,742E-04 0,0121977 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 3,000 6,143E-04 0,01293656 ! regulation of bone remodeling GO:0046850 143 57 3,000 6,143E-04 0,01282599 ! positive regulation of caspase activity GO:0043280 108 57 3,000 6,143E-04 0,01271729 GO:0010952|positive regulation of peptidase activity, ! negative regulation of DNA replication GO:0008156 45 25 2,000 6,341E-04 0,01301732 ! protein tetramerization GO:0051262 57 25 2,000 6,341E-04 0,01290885 ! positive regulation of cell migration GO:0030335 137 58 3,000 6,563E-04 0,01325037 ! regulation of tissue remodeling GO:0034103 146 58 3,000 6,563E-04 0,01314176 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 1,000 6,745E-04 0,01339734 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 1,000 6,745E-04 0,0132893 ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 1,000 6,745E-04 0,01318299 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! establishment of spindle localization GO:0051293 16 6 1,000 6,745E-04 0,01307836 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 11 6 1,000 6,745E-04 0,01297538 ! negative regulation of gliogenesis GO:0014014 18 6 1,000 6,745E-04 0,01287401 GO:0045686|negative regulation of glial cell differentiation, ! response to UV-C GO:0010225 14 6 1,000 6,745E-04 0,01277421 ! astrocyte development GO:0014002 16 6 1,000 6,745E-04 0,01267595 ! response to copper ion GO:0046688 10 6 1,000 6,745E-04 0,01257918 ! Schwann cell development GO:0014044 15 6 1,000 6,745E-04 0,01248389 ! regulation of myeloid cell apoptosis GO:0033032 14 6 1,000 6,745E-04 0,01239002 ! negative regulation of axon extension GO:0030517 24 6 1,000 6,745E-04 0,01229756 ! triglyceride catabolic process GO:0019433 10 6 1,000 6,745E-04 0,01220647 ! negative regulation of B cell activation GO:0050869 14 6 1,000 6,745E-04 0,01211671 ! metallo-sulfur cluster assembly GO:0031163 6 6 1,000 6,745E-04 0,01202827 GO:0016226|iron-sulfur cluster assembly, ! myelination GO:0042552 50 26 2,000 7,132E-04 0,01262594 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 2,000 7,132E-04 0,01253511 ! mitochondrial membrane organization GO:0007006 60 27 2,000 7,984E-04 0,01393146 ! regulation of chromosome organization GO:0033044 49 27 2,000 7,984E-04 0,01383266 ! negative regulation of lymphocyte activation GO:0051250 55 27 2,000 7,984E-04 0,01373524 ! DNA damage response, signal transduction GO:0042770 136 62 3,000 8,448E-04 0,01443324 ! regulation of homeostatic process GO:0032844 148 62 3,000 8,448E-04 0,01433301 ! peptidyl-tyrosine modification GO:0018212 57 28 2,000 8,897E-04 0,01499011 ! regulation of helicase activity GO:0051095 16 7 1,000 9,401E-04 0,01573084 ! cytokinesis during cell cycle GO:0033205 14 7 1,000 9,401E-04 0,01562383 ! prostate gland development GO:0030850 14 7 1,000 9,401E-04 0,01551826 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 9,401E-04 0,01541411 ! N-terminal protein amino acid acetylation GO:0006474 14 7 1,000 9,401E-04 0,01531135 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 1,000 9,401E-04 0,01520995 GO:0031958|corticosteroid receptor signaling pathway, ! oxaloacetate metabolic process GO:0006107 13 7 1,000 9,401E-04 0,01510989 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 1,000 9,401E-04 0,01501113 ! adrenal gland development GO:0030325 17 7 1,000 9,401E-04 0,01491365 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 1,000 9,401E-04 0,01481744 ! glycerol ether catabolic process GO:0044269 12 7 1,000 9,401E-04 0,01472245 GO:0046464|acylglycerol catabolic process, ! organ growth GO:0035265 15 7 1,000 9,401E-04 0,01462868 ! male sex determination GO:0030238 15 7 1,000 9,401E-04 0,01453609 ! positive regulation of mitotic cell cycle GO:0045931 14 7 1,000 9,401E-04 0,01444467 ! centrosome duplication GO:0051298 14 7 1,000 9,401E-04 0,01435439 ! G1 DNA damage checkpoint GO:0031571 20 7 1,000 9,401E-04 0,01426523 ! cranial nerve morphogenesis GO:0021602 12 7 1,000 9,401E-04 0,01417718 ! peptidyl-threonine modification GO:0018210 26 7 1,000 9,401E-04 0,0140902 ! regulation of protein homodimerization activity GO:0043496 18 7 1,000 9,401E-04 0,01400428 ! protein amino acid autophosphorylation GO:0046777 157 64 3,000 9,521E-04 0,01409755 ! cellular iron ion homeostasis GO:0006879 57 29 2,000 9,874E-04 0,01453183 ! response to organic cyclic substance GO:0014070 58 29 2,000 9,874E-04 0,01444481 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 2,000 9,874E-04 0,01435883 ! positive regulation of cell motion GO:0051272 157 65 3,000 1,009E-03 0,01458917 ! gonad development GO:0008406 115 66 3,000 1,069E-03 0,01535773 ! positive regulation of multicellular organism growth GO:0040018 55 30 2,000 1,092E-03 0,01559629 ! tissue homeostasis GO:0001894 50 30 2,000 1,092E-03 0,01550561 GO:0048871|multicellular organismal homeostasis, ! negative regulation of cell growth GO:0030308 142 67 3,000 1,131E-03 0,01596508 ! cell junction assembly GO:0034329 85 31 2,000 1,203E-03 0,01688511 ! male gonad development GO:0008584 56 31 2,000 1,203E-03 0,01678863 ! iron ion homeostasis GO:0055072 60 31 2,000 1,203E-03 0,01669324 ! ensheathment of neurons GO:0007272 64 31 2,000 1,203E-03 0,01659892 GO:0008366|axon ensheathment, ! negative regulation of leukocyte activation GO:0002695 60 31 2,000 1,203E-03 0,01650567 ! response to heat GO:0009408 54 31 2,000 1,203E-03 0,01641346 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 1,000 1,248E-03 0,01693655 ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 1,000 1,248E-03 0,01684298 ! generation of neurons in the forebrain GO:0021872 18 8 1,000 1,248E-03 0,01675044 ! male meiosis GO:0007140 9 8 1,000 1,248E-03 0,0166589 ! succinate metabolic process GO:0006105 17 8 1,000 1,248E-03 0,01656837 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 1,000 1,248E-03 0,01647881 ! glycerolipid catabolic process GO:0046503 14 8 1,000 1,248E-03 0,01639021 ! pigment granule organization GO:0048753 17 8 1,000 1,248E-03 0,01630256 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 1,248E-03 0,01621585 ! astrocyte differentiation GO:0048708 19 8 1,000 1,248E-03 0,01613005 ! ER overload response GO:0006983 13 8 1,000 1,248E-03 0,01604515 ! regulation of pigmentation during development GO:0048070 25 8 1,000 1,248E-03 0,01596115 ! melanin metabolic process GO:0006582 17 8 1,000 1,248E-03 0,01587802 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 1,000 1,248E-03 0,01579575 ! Schwann cell differentiation GO:0014037 21 8 1,000 1,248E-03 0,01571433 ! response to UV-B GO:0010224 17 8 1,000 1,248E-03 0,01563374 ! response to tumor cell GO:0002347 16 8 1,000 1,248E-03 0,01555398 ! regulation of respiratory burst GO:0060263 12 8 1,000 1,248E-03 0,01547502 ! blastocyst growth GO:0001832 19 8 1,000 1,248E-03 0,01539687 ! negative regulation of cell size GO:0045792 144 69 3,000 1,262E-03 0,01548976 ! negative regulation of protein kinase activity GO:0006469 144 69 3,000 1,262E-03 0,01541231 ! spindle organization GO:0007051 50 32 2,000 1,32E-03 0,01604878 ! peripheral nervous system development GO:0007422 68 32 2,000 1,32E-03 0,01596933 ! hindbrain development GO:0030902 65 32 2,000 1,32E-03 0,01589066 ! positive regulation of catabolic process GO:0009896 72 32 2,000 1,32E-03 0,01581277 ! negative regulation of kinase activity GO:0033673 145 70 3,000 1,331E-03 0,01586377 ! negative regulation of protein transport GO:0051224 74 33 2,000 1,445E-03 0,01713946 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 1,597E-03 0,01885067 ! neutral lipid catabolic process GO:0046461 14 9 1,000 1,597E-03 0,01876004 ! cellular copper ion homeostasis GO:0006878 12 9 1,000 1,597E-03 0,01867028 ! artery development GO:0060840 25 9 1,000 1,597E-03 0,01858137 GO:0048844|artery morphogenesis, ! regulation of glycolysis GO:0006110 20 9 1,000 1,597E-03 0,01849331 ! microtubule bundle formation GO:0001578 22 9 1,000 1,597E-03 0,01840608 ! middle ear morphogenesis GO:0042474 14 9 1,000 1,597E-03 0,01831966 ! T cell selection GO:0045058 27 9 1,000 1,597E-03 0,01823406 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 1,000 1,597E-03 0,01814925 ! regulation of mitochondrial membrane potential GO:0051881 19 9 1,000 1,597E-03 0,01806522 ! regulation of cell division GO:0051302 17 9 1,000 1,597E-03 0,01798197 ! regulation of telomere maintenance GO:0032204 17 9 1,000 1,597E-03 0,01789949 ! negative regulation of transferase activity GO:0051348 155 74 3,000 1,636E-03 0,01824611 ! organelle localization GO:0051640 155 74 3,000 1,636E-03 0,01816317 ! negative regulation of DNA metabolic process GO:0051053 65 35 2,000 1,717E-03 0,01897479 ! eye development GO:0001654 155 75 3,000 1,719E-03 0,01891365 ! negative regulation of hydrolase activity GO:0051346 66 36 2,000 1,863E-03 0,02041215 ! positive regulation of cell development GO:0010720 85 36 2,000 1,863E-03 0,02032102 ! regulation of catabolic process GO:0009894 173 77 3,000 1,894E-03 0,02055979 ! regulation of developmental growth GO:0048638 16 10 1,000 1,988E-03 0,02148596 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 1,000 1,988E-03 0,02139131 ! COPI coating of Golgi vesicle GO:0048205 23 10 1,000 1,988E-03 0,02129749 GO:0048200|Golgi transport vesicle coating, ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 1,000 1,988E-03 0,02120448 ! phosphagen metabolic process GO:0006599 17 10 1,000 1,988E-03 0,02111229 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 1,000 1,988E-03 0,0210209 ! B cell proliferation GO:0042100 19 10 1,000 1,988E-03 0,02093029 ! multicellular organism growth GO:0035264 19 10 1,000 1,988E-03 0,02084046 ! motor axon guidance GO:0008045 22 10 1,000 1,988E-03 0,0207514 ! copper ion homeostasis GO:0055070 13 10 1,000 1,988E-03 0,02066309 ! regulation of bone resorption GO:0045124 25 10 1,000 1,988E-03 0,02057554 ! protein heterooligomerization GO:0051291 17 10 1,000 1,988E-03 0,02048872 ! brain morphogenesis GO:0048854 23 10 1,000 1,988E-03 0,02040263 ! alpha-beta T cell differentiation GO:0046632 24 10 1,000 1,988E-03 0,02031727 ! induction of an organ GO:0001759 17 10 1,000 1,988E-03 0,02023261 ! negative regulation of MAPKKK cascade GO:0043409 20 10 1,000 1,988E-03 0,02014866 ! negative regulation of BMP signaling pathway GO:0030514 19 10 1,000 1,988E-03 0,0200654 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 1,000 1,988E-03 0,01998283 GO:0043470|regulation of carbohydrate catabolic process, ! natural killer cell mediated immunity GO:0002228 19 10 1,000 1,988E-03 0,01990093 GO:0042267|natural killer cell mediated cytotoxicity, ! response to nicotine GO:0035094 20 10 1,000 1,988E-03 0,0198197 ! cell junction organization GO:0034330 96 37 2,000 2,018E-03 0,02003631 ! female gonad development GO:0008585 71 37 2,000 2,018E-03 0,01995519 ! negative regulation of cell activation GO:0050866 69 37 2,000 2,018E-03 0,01987473 ! response to steroid hormone stimulus GO:0048545 147 79 3,000 2,08E-03 0,02041063 ! development of primary sexual characteristics GO:0045137 143 80 3,000 2,178E-03 0,02128658 ! positive regulation of DNA metabolic process GO:0051054 77 38 2,000 2,18E-03 0,02121446 ! meiosis I GO:0007127 74 38 2,000 2,18E-03 0,02113027 ! meiosis GO:0007126 143 81 3,000 2,279E-03 0,0220107 GO:0051327|M phase of meiotic cell cycle, ! response to hypoxia GO:0001666 178 81 3,000 2,279E-03 0,02192405 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 3,000 2,279E-03 0,02183807 ! meiotic cell cycle GO:0051321 144 82 3,000 2,384E-03 0,02274828 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 1,000 2,419E-03 0,02298992 ! Golgi vesicle budding GO:0048194 26 11 1,000 2,419E-03 0,02290081 ! detection of mechanical stimulus GO:0050982 22 11 1,000 2,419E-03 0,02281239 ! keratinocyte proliferation GO:0043616 19 11 1,000 2,419E-03 0,02272465 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 1,000 2,419E-03 0,02263758 GO:0010812|negative regulation of cell-substrate adhesion, ! peptide or protein amino-terminal blocking GO:0018409 22 11 1,000 2,419E-03 0,02255118 ! regulation of intracellular pH GO:0051453 21 11 1,000 2,419E-03 0,02246544 ! behavioral fear response GO:0001662 27 11 1,000 2,419E-03 0,02238034 GO:0002209|behavioral defense response, ! negative regulation of ossification GO:0030279 27 11 1,000 2,419E-03 0,02229588 ! alpha-beta T cell activation GO:0046631 26 11 1,000 2,419E-03 0,02221207 ! negative regulation of axonogenesis GO:0050771 37 11 1,000 2,419E-03 0,02212887 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 1,000 2,419E-03 0,0220463 ! DNA methylation GO:0006306 19 11 1,000 2,419E-03 0,02196435 GO:0006305|DNA alkylation, ! neuroblast proliferation GO:0007405 25 11 1,000 2,419E-03 0,021883 ! thymus development GO:0048538 29 11 1,000 2,419E-03 0,02180225 ! cardiac cell differentiation GO:0035051 36 11 1,000 2,419E-03 0,02172209 ! regulation of embryonic development GO:0045995 35 11 1,000 2,419E-03 0,02164253 ! response to drug GO:0042493 149 83 3,000 2,491E-03 0,02221284 ! response to oxygen levels GO:0070482 183 83 3,000 2,491E-03 0,02213207 ! mammary gland development GO:0030879 93 40 2,000 2,527E-03 0,02237142 ! learning GO:0007612 82 40 2,000 2,527E-03 0,02229066 ! development of primary female sexual characteristics GO:0046545 80 40 2,000 2,527E-03 0,02221047 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 73 40 2,000 2,527E-03 0,02213087 ! regulation of action potential in neuron GO:0019228 80 40 2,000 2,527E-03 0,02205183 ! mesenchymal cell development GO:0014031 94 41 2,000 2,713E-03 0,02359044 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! negative regulation of growth GO:0045926 168 85 3,000 2,716E-03 0,02353211 ! regulation of neuron differentiation GO:0045664 187 85 3,000 2,716E-03 0,02344896 ! positive regulation of cellular catabolic process GO:0031331 34 12 1,000 2,889E-03 0,02485374 ! virus-host interaction GO:0019048 30 12 1,000 2,889E-03 0,02476653 ! regulation of B cell proliferation GO:0030888 22 12 1,000 2,889E-03 0,02467994 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 1,000 2,889E-03 0,02459395 ! polyamine metabolic process GO:0006595 18 12 1,000 2,889E-03 0,02450855 ! mitotic spindle organization GO:0007052 23 12 1,000 2,889E-03 0,02442375 ! cranial nerve development GO:0021545 23 12 1,000 2,889E-03 0,02433953 ! histone acetylation GO:0016573 27 12 1,000 2,889E-03 0,02425588 ! peptidyl-lysine modification GO:0018205 21 12 1,000 2,889E-03 0,02417282 ! T cell homeostasis GO:0043029 28 12 1,000 2,889E-03 0,02409032 ! leukocyte mediated cytotoxicity GO:0001909 28 12 1,000 2,889E-03 0,02400838 ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 1,000 2,889E-03 0,02392699 ! developmental induction GO:0031128 22 12 1,000 2,889E-03 0,02384616 GO:0045168|cell-cell signaling involved in cell fate specification, ! localization within membrane GO:0051668 26 12 1,000 2,889E-03 0,02376587 ! regulation of intracellular protein transport GO:0033157 86 42 2,000 2,908E-03 0,02383696 ! T cell differentiation GO:0030217 93 42 2,000 2,908E-03 0,02375724 ! regulation of T cell differentiation GO:0045580 78 42 2,000 2,908E-03 0,02367804 ! cytokinesis GO:0000910 84 42 2,000 2,908E-03 0,02359938 ! one-carbon metabolic process GO:0006730 167 88 3,000 3,079E-03 0,02491061 ! development of primary male sexual characteristics GO:0046546 80 43 2,000 3,11E-03 0,0250769 ! regulation of T cell proliferation GO:0042129 80 43 2,000 3,11E-03 0,02499441 ! tube morphogenesis GO:0035239 194 89 3,000 3,207E-03 0,02569099 ! response to reactive oxygen species GO:0000302 75 44 2,000 3,321E-03 0,02651584 ! regulation of cell cycle process GO:0010564 161 90 3,000 3,339E-03 0,02657084 ! negative regulation of cell projection organization GO:0031345 42 13 1,000 3,399E-03 0,02696307 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 1,000 3,399E-03 0,02687581 ! endocrine pancreas development GO:0031018 25 13 1,000 3,399E-03 0,02678912 ! positive regulation of cell growth GO:0030307 24 13 1,000 3,399E-03 0,02670298 ! regulation of skeletal muscle fiber development GO:0048742 32 13 1,000 3,399E-03 0,02661739 ! plasma membrane organization GO:0007009 27 13 1,000 3,399E-03 0,02653235 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 1,000 3,399E-03 0,02644786 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 35 13 1,000 3,399E-03 0,02636389 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 1,000 3,399E-03 0,02628046 ! regulation of monooxygenase activity GO:0032768 35 13 1,000 3,399E-03 0,02619756 ! gland morphogenesis GO:0022612 31 13 1,000 3,399E-03 0,02611518 ! spleen development GO:0048536 24 13 1,000 3,399E-03 0,02603331 ! digestive tract morphogenesis GO:0048546 31 13 1,000 3,399E-03 0,02595196 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! ossification GO:0001503 205 91 3,000 3,474E-03 0,02644114 ! biopolymer methylation GO:0043414 91 45 2,000 3,541E-03 0,02686436 ! B cell differentiation GO:0030183 124 45 2,000 3,541E-03 0,02678118 ! female gamete generation GO:0007292 71 45 2,000 3,541E-03 0,02669853 ! developmental growth GO:0048589 88 45 2,000 3,541E-03 0,02661638 ! maintenance of location in cell GO:0051651 101 45 2,000 3,541E-03 0,02653473 ! bone development GO:0060348 206 92 3,000 3,613E-03 0,02699371 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 2,000 3,769E-03 0,02807313 ! cell growth GO:0016049 90 46 2,000 3,769E-03 0,0279878 ! regulation of membrane potential GO:0042391 179 94 3,000 3,902E-03 0,02888792 ! rRNA transcription GO:0009303 28 14 1,000 3,948E-03 0,02914066 ! regulation of S phase GO:0033261 26 14 1,000 3,948E-03 0,02905288 ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 1,000 3,948E-03 0,02896564 ! hair follicle morphogenesis GO:0031069 27 14 1,000 3,948E-03 0,02887891 ! fear response GO:0042596 34 14 1,000 3,948E-03 0,02879271 ! negative regulation of caspase activity GO:0043154 23 14 1,000 3,948E-03 0,02870702 ! bone mineralization GO:0030282 18 14 1,000 3,948E-03 0,02862183 ! negative regulation of protein import into nucleus GO:0042308 33 14 1,000 3,948E-03 0,02853715 ! T cell differentiation in the thymus GO:0033077 37 14 1,000 3,948E-03 0,02845297 ! regulation of cellular pH GO:0030641 27 14 1,000 3,948E-03 0,02836929 ! positive regulation of Ras GTPase activity GO:0032320 42 14 1,000 3,948E-03 0,02828609 ! positive regulation of bone mineralization GO:0030501 32 14 1,000 3,948E-03 0,02820338 ! regulation of axon extension GO:0030516 43 14 1,000 3,948E-03 0,02812116 ! mitochondrial transport GO:0006839 94 48 2,000 4,252E-03 0,03019732 ! cellular component disassembly GO:0022411 89 48 2,000 4,252E-03 0,03010979 ! male sex differentiation GO:0046661 93 48 2,000 4,252E-03 0,03002277 ! methylation GO:0032259 97 48 2,000 4,252E-03 0,02993624 ! regulation of protein localization GO:0032880 188 97 3,000 4,364E-03 0,03063878 ! regulation of lymphocyte differentiation GO:0045619 92 49 2,000 4,507E-03 0,03154894 ! regulation of mast cell proliferation GO:0070666 89 49 2,000 4,507E-03 0,0314588 ! protein homooligomerization GO:0051260 84 49 2,000 4,507E-03 0,03136918 ! regulation of skeletal muscle tissue development GO:0048641 35 15 1,000 4,535E-03 0,03147705 ! N-terminal protein amino acid modification GO:0031365 30 15 1,000 4,535E-03 0,03138788 ! negative regulation of bone remodeling GO:0046851 34 15 1,000 4,535E-03 0,03129922 ! positive regulation of GTPase activity GO:0043547 43 15 1,000 4,535E-03 0,03121105 ! regulation of mRNA processing GO:0050684 26 15 1,000 4,535E-03 0,03112338 ! vesicle coating GO:0006901 38 15 1,000 4,535E-03 0,0310362 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 1,000 4,535E-03 0,0309495 ! G1/S transition checkpoint GO:0031575 37 15 1,000 4,535E-03 0,03086329 ! positive regulation of biomineral formation GO:0070169 33 15 1,000 4,535E-03 0,03077756 ! cell killing GO:0001906 32 15 1,000 4,535E-03 0,03069231 ! lymphocyte homeostasis GO:0002260 33 15 1,000 4,535E-03 0,03060752 ! epithelial to mesenchymal transition GO:0001837 30 15 1,000 4,535E-03 0,0305232 ! regulation of action potential GO:0001508 102 50 2,000 4,771E-03 0,03202041 ! endocrine system development GO:0035270 109 50 2,000 4,771E-03 0,03193269 ! regulation of ossification GO:0030278 123 50 2,000 4,771E-03 0,03184544 ! regulation of gene expression, epigenetic GO:0040029 116 50 2,000 4,771E-03 0,03175867 ! response to temperature stimulus GO:0009266 84 51 2,000 5,044E-03 0,03348545 ! negative regulation of immune system process GO:0002683 101 51 2,000 5,044E-03 0,0333947 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 5,16E-03 0,03407136 ! positive regulation of cell size GO:0045793 29 16 1,000 5,16E-03 0,03397953 ! heterophilic cell adhesion GO:0007157 43 16 1,000 5,16E-03 0,03388818 ! negative regulation of tissue remodeling GO:0034104 37 16 1,000 5,16E-03 0,03379733 ! biomineral formation GO:0031214 22 16 1,000 5,16E-03 0,03370696 ! DNA-dependent DNA replication GO:0006261 82 52 2,000 5,326E-03 0,03469983 ! vesicle organization GO:0016050 127 53 2,000 5,618E-03 0,03650268 ! regulation of leukocyte proliferation GO:0070663 97 53 2,000 5,618E-03 0,03640585 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! metencephalon development GO:0022037 32 17 1,000 5,822E-03 0,03762883 ! negative regulation of cell cycle process GO:0010948 35 17 1,000 5,822E-03 0,03752955 ! glial cell development GO:0021782 28 17 1,000 5,822E-03 0,03743078 ! negative regulation of peptidase activity GO:0010466 28 17 1,000 5,822E-03 0,03733254 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 1,000 5,822E-03 0,03723481 ! regulation of survival gene product expression GO:0045884 38 17 1,000 5,822E-03 0,03713759 ! negative regulation of microtubule depolymerization GO:0007026 50 17 1,000 5,822E-03 0,03704088 GO:0031114|regulation of microtubule depolymerization, ! membrane budding GO:0006900 42 17 1,000 5,822E-03 0,03694467 ! regulation of protein binding GO:0043393 33 17 1,000 5,822E-03 0,03684896 ! DNA unwinding during replication GO:0006268 26 17 1,000 5,822E-03 0,03675374 ! branched chain family amino acid metabolic process GO:0009081 37 17 1,000 5,822E-03 0,03665901 ! negative regulation of homeostatic process GO:0032845 36 17 1,000 5,822E-03 0,03656478 ! regulation of angiogenesis GO:0045765 125 54 2,000 5,919E-03 0,03707835 ! regulation of multicellular organism growth GO:0040014 90 55 2,000 6,23E-03 0,03892397 ! regulation of viral genome replication GO:0045069 30 18 1,000 6,521E-03 0,04063906 ! centrosome cycle GO:0007098 26 18 1,000 6,521E-03 0,04053566 ! epidermis morphogenesis GO:0048730 43 18 1,000 6,521E-03 0,04043277 ! negative regulation of protein catabolic process GO:0042177 42 18 1,000 6,521E-03 0,04033041 ! regulation of BMP signaling pathway GO:0030510 33 18 1,000 6,521E-03 0,04022857 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 1,000 6,521E-03 0,04012724 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 1,000 6,521E-03 0,04002641 ! nerve development GO:0021675 34 18 1,000 6,521E-03 0,0399261 ! defense response to virus GO:0051607 43 18 1,000 6,521E-03 0,03982628 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 1,000 6,521E-03 0,03972696 ! regulation of protein catabolic process GO:0042176 126 56 2,000 6,55E-03 0,03980433 ! heart morphogenesis GO:0003007 105 57 2,000 6,88E-03 0,04170455 ! nucleotide-excision repair GO:0006289 91 57 2,000 6,88E-03 0,04160133 ! regulation of intracellular transport GO:0032386 108 57 2,000 6,88E-03 0,04149861 ! maintenance of location GO:0051235 124 58 2,000 7,219E-03 0,04343898 ! positive regulation of translation GO:0045727 31 19 1,000 7,256E-03 0,04355177 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 1,000 7,256E-03 0,04344502 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 1,000 7,256E-03 0,0433388 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 1,000 7,256E-03 0,0432331 ! cerebral cortex development GO:0021987 40 19 1,000 7,256E-03 0,04312791 ! neuromuscular junction development GO:0007528 43 19 1,000 7,256E-03 0,04302323 ! regulation of endothelial cell migration GO:0010594 45 19 1,000 7,256E-03 0,04291906 ! visual learning GO:0008542 38 19 1,000 7,256E-03 0,04281539 ! cellular pigmentation GO:0033059 37 19 1,000 7,256E-03 0,04271222 ! proximal/distal pattern formation GO:0009954 33 19 1,000 7,256E-03 0,04260954 ! establishment of organelle localization GO:0051656 122 59 2,000 7,568E-03 0,04433902 ! DNA catabolic process GO:0006308 94 60 2,000 7,927E-03 0,04633141 ! positive regulation of ossification GO:0045778 50 20 1,000 8,026E-03 0,04679619 ! skin development GO:0043588 42 20 1,000 8,026E-03 0,04668477 ! phosphoinositide phosphorylation GO:0046854 40 20 1,000 8,026E-03 0,04657388 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 1,000 8,026E-03 0,04646352 ! protein amino acid acetylation GO:0006473 41 20 1,000 8,026E-03 0,04635368 ! regulation of carbohydrate metabolic process GO:0006109 37 20 1,000 8,026E-03 0,04624435 GO:0010675|regulation of cellular carbohydrate metabolic process, ! pancreas development GO:0031016 40 20 1,000 8,026E-03 0,04613554 ! DNA duplex unwinding GO:0032508 30 20 1,000 8,026E-03 0,04602724 GO:0032392|DNA geometric change, ! peptidyl-serine phosphorylation GO:0018105 44 20 1,000 8,026E-03 0,04591945 ! actin filament bundle formation GO:0051017 47 20 1,000 8,026E-03 0,04581216 ! estrogen receptor signaling pathway GO:0030520 45 20 1,000 8,026E-03 0,04570537 ! negative regulation of translation GO:0017148 32 20 1,000 8,026E-03 0,04559908 ! camera-type eye development GO:0043010 126 61 2,000 8,296E-03 0,04702517 ! lipid phosphorylation GO:0046834 43 21 1,000 8,832E-03 0,04994298 ! ovarian follicle development GO:0001541 39 21 1,000 8,832E-03 0,04982764 ! ribosomal small subunit biogenesis GO:0042274 25 21 1,000 8,832E-03 0,04971283 ! collagen fibril organization GO:0030199 62 21 1,000 8,832E-03 0,04959854 ! positive regulation of osteoblast differentiation GO:0045669 52 21 1,000 8,832E-03 0,04948479 ! camera-type eye morphogenesis GO:0048593 47 21 1,000 8,832E-03 0,04937155 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 1,000 8,832E-03 0,04925883 ! skeletal system morphogenesis GO:0048705 118 63 2,000 9,064E-03 0,05044085 ! positive regulation of protein catabolic process GO:0045732 44 22 1,000 9,672E-03 0,05369913 ! reciprocal meiotic recombination GO:0007131 44 22 1,000 9,672E-03 0,05357736 ! positive regulation of bone remodeling GO:0046852 54 22 1,000 9,672E-03 0,05345614 GO:0034105|positive regulation of tissue remodeling, ! cellular response to starvation GO:0009267 37 22 1,000 9,672E-03 0,05333548 ! D-ribose metabolic process GO:0006014 36 22 1,000 9,672E-03 0,05321535 ! renal system process GO:0003014 42 22 1,000 9,672E-03 0,05309577 ! response to glucocorticoid stimulus GO:0051384 42 22 1,000 9,672E-03 0,05297672 ! peptidyl-serine modification GO:0018209 50 22 1,000 9,672E-03 0,0528582 ! response to cytokine stimulus GO:0034097 69 22 1,000 9,672E-03 0,05274021 ! gut development GO:0048565 44 22 1,000 9,672E-03 0,05262275 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 1,000 9,672E-03 0,05250581 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 1,000 9,672E-03 0,05238939 ! protein stabilization GO:0050821 41 22 1,000 9,672E-03 0,05227349 ! lymphocyte mediated immunity GO:0002449 122 65 2,000 9,872E-03 0,05323947 ! ear development GO:0043583 114 66 2,000 0,01029128 0,05537798 ! steroid hormone receptor signaling pathway GO:0030518 146 66 2,000 0,01029128 0,05525627 ! positive regulation of DNA replication GO:0045740 44 23 1,000 0,01054569 0,05649808 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 1,000 0,01054569 0,05637445 ! regeneration GO:0031099 42 23 1,000 0,01054569 0,05625136 ! visual behavior GO:0007632 46 23 1,000 0,01054569 0,05612881 ! response to ethanol GO:0045471 47 23 1,000 0,01054569 0,05600679 ! deoxyribonucleotide metabolic process GO:0009262 37 23 1,000 0,01054569 0,0558853 ! cellular response to reactive oxygen species GO:0034614 35 23 1,000 0,01054569 0,05576434 ! vesicle targeting GO:0006903 49 23 1,000 0,01054569 0,0556439 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 1,000 0,01054569 0,05552398 ! DNA modification GO:0006304 36 23 1,000 0,01054569 0,05540457 ! regulation of bone mineralization GO:0030500 54 23 1,000 0,01054569 0,05528568 ! activation of MAPK activity GO:0000187 124 67 2,000 0,01072069 0,05608276 ! regulation of cellular catabolic process GO:0031329 55 24 1,000 0,01145341 0,05978778 ! negative regulation of phosphorylation GO:0042326 52 24 1,000 0,01145341 0,0596603 ! pallium development GO:0021543 56 24 1,000 0,01145341 0,05953336 ! regulation of oxidoreductase activity GO:0051341 48 24 1,000 0,01145341 0,05940697 ! platelet activation GO:0030168 41 24 1,000 0,01145341 0,0592811 ! pyrimidine nucleoside metabolic process GO:0006213 34 24 1,000 0,01145341 0,05915577 ! negative regulation of catabolic process GO:0009895 52 24 1,000 0,01145341 0,05903097 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 1,000 0,01145341 0,0589067 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 1,000 0,01145341 0,05878294 ! positive regulation of cell adhesion GO:0045785 61 24 1,000 0,01145341 0,05865971 ! response to corticosteroid stimulus GO:0031960 46 24 1,000 0,01145341 0,05853699 ! regulation of viral reproduction GO:0050792 41 24 1,000 0,01145341 0,05841478 ! lung development GO:0030324 165 69 2,000 0,01161028 0,05909149 ! homeostasis of number of cells GO:0048872 131 69 2,000 0,01161028 0,05896864 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 2,000 0,01161028 0,0588463 ! protein import into nucleus, translocation GO:0000060 51 25 1,000 0,01239422 0,06268961 ! dicarboxylic acid metabolic process GO:0043648 48 25 1,000 0,01239422 0,06256009 ! vasculogenesis GO:0001570 49 25 1,000 0,01239422 0,0624311 ! interaction with host GO:0051701 66 25 1,000 0,01239422 0,06230264 ! lymphocyte proliferation GO:0046651 55 25 1,000 0,01239422 0,06217471 ! regulation of biomineral formation GO:0070167 56 25 1,000 0,01239422 0,0620473 ! leukocyte homeostasis GO:0001776 50 25 1,000 0,01239422 0,06192041 ! liver development GO:0001889 55 25 1,000 0,01239422 0,06179405 ! cell cycle checkpoint GO:0000075 145 71 2,000 0,01254115 0,06239927 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 2,000 0,01254115 0,06227244 ! respiratory tube development GO:0030323 171 72 2,000 0,01302216 0,06452971 ! actin filament organization GO:0007015 167 72 2,000 0,01302216 0,06439908 ! B cell activation GO:0042113 179 72 2,000 0,01302216 0,06426898 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 1,000 0,01336764 0,06584101 ! molting cycle process GO:0022404 52 26 1,000 0,01336764 0,06570853 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! protein amino acid alkylation GO:0008213 59 26 1,000 0,01336764 0,06557659 GO:0006479|protein amino acid methylation, ! regulation of transcription factor import into nucleus GO:0042990 58 26 1,000 0,01336764 0,06544517 ! microtubule organizing center organization GO:0031023 42 26 1,000 0,01336764 0,06531428 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 1,000 0,01336764 0,06518391 ! multicellular organismal response to stress GO:0033555 61 26 1,000 0,01336764 0,06505407 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 1,000 0,01336764 0,06492473 GO:0045936|negative regulation of phosphate metabolic process, ! osteoblast differentiation GO:0001649 63 26 1,000 0,01336764 0,06479591 ! response to endoplasmic reticulum stress GO:0034976 46 26 1,000 0,01336764 0,06466761 ! pentose metabolic process GO:0019321 43 26 1,000 0,01336764 0,0645398 ! response to estradiol stimulus GO:0032355 43 26 1,000 0,01336764 0,06441251 ! positive regulation of nuclear division GO:0051785 41 26 1,000 0,01336764 0,06428571 GO:0045840|positive regulation of mitosis, ! regulation of osteoblast differentiation GO:0045667 68 26 1,000 0,01336764 0,06415941 ! blastocyst development GO:0001824 50 26 1,000 0,01336764 0,06403361 ! humoral immune response GO:0006959 115 73 2,000 0,0135136 0,06460609 ! respiratory system development GO:0060541 175 74 2,000 0,01401548 0,06687464 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 1,000 0,01437318 0,06844772 ! regulation of endothelial cell proliferation GO:0001936 60 27 1,000 0,01437318 0,06831455 ! response to starvation GO:0042594 47 27 1,000 0,01437318 0,0681819 ! response to toxin GO:0009636 49 27 1,000 0,01437318 0,06804977 ! cellular response to oxidative stress GO:0034599 43 27 1,000 0,01437318 0,06791814 ! cellular response to nutrient levels GO:0031669 45 27 1,000 0,01437318 0,06778703 ! leukocyte proliferation GO:0070661 59 27 1,000 0,01437318 0,06765642 GO:0032943|mononuclear cell proliferation, ! regulation of transcription factor activity GO:0051090 137 75 2,000 0,01452785 0,06825293 GO:0090046|regulation of transcription regulator activity, ! leukocyte mediated immunity GO:0002443 136 75 2,000 0,01452785 0,06812193 ! axon guidance GO:0007411 162 75 2,000 0,01452785 0,06799143 ! cell-matrix adhesion GO:0007160 181 76 2,000 0,01505072 0,07030382 ! learning or memory GO:0007611 161 76 2,000 0,01505072 0,07016965 ! lymphocyte differentiation GO:0030098 193 76 2,000 0,01505072 0,070036 ! regulation of fibroblast proliferation GO:0048145 56 28 1,000 0,01541037 0,07157326 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 1,000 0,01541037 0,07143745 ! protein amino acid acylation GO:0043543 59 28 1,000 0,01541037 0,07130215 ! dendrite development GO:0016358 67 28 1,000 0,01541037 0,07116736 ! base-excision repair GO:0006284 41 28 1,000 0,01541037 0,07103308 ! translational initiation GO:0006413 66 29 1,000 0,01647874 0,0758146 ! ER-nuclear signaling pathway GO:0006984 52 29 1,000 0,01647874 0,07567209 ! somitogenesis GO:0001756 52 29 1,000 0,01647874 0,07553012 ! synaptogenesis GO:0007416 46 29 1,000 0,01647874 0,07538868 ! negative regulation of neuron differentiation GO:0045665 46 29 1,000 0,01647874 0,07524776 ! negative regulation of neuron apoptosis GO:0043524 69 29 1,000 0,01647874 0,07510738 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 2,000 0,01668258 0,07589485 ! negative regulation of organelle organization GO:0010639 181 80 2,000 0,01724768 0,07831985 ! complement activation, classical pathway GO:0006958 51 30 1,000 0,01757781 0,07967086 ! negative regulation of protein kinase cascade GO:0010741 72 30 1,000 0,01757781 0,07952332 ! negative regulation of transcription regulator activity GO:0090048 57 30 1,000 0,01757781 0,07937633 GO:0043433|negative regulation of transcription factor activity, ! regulation of B cell activation GO:0050864 55 30 1,000 0,01757781 0,07922988 ! positive regulation of phosphorylation GO:0042327 149 81 2,000 0,01782338 0,08018879 ! cell-substrate adhesion GO:0031589 189 82 2,000 0,01840969 0,08267441 ! ovulation cycle process GO:0022602 55 31 1,000 0,01870714 0,08385602 ! cellular response to extracellular stimulus GO:0031668 52 31 1,000 0,01870714 0,08370244 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 1,000 0,01870714 0,08354942 ! eye morphogenesis GO:0048592 65 31 1,000 0,01870714 0,08339696 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 2,000 0,01900663 0,08457778 GO:0045937|positive regulation of phosphate metabolic process, ! response to metal ion GO:0010038 158 84 2,000 0,0196142 0,08712273 ! T cell activation GO:0042110 189 84 2,000 0,0196142 0,08696461 ! response to nutrient GO:0007584 135 84 2,000 0,0196142 0,08680707 ! regulation of ligase activity GO:0051340 147 84 2,000 0,0196142 0,08665009 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 1,000 0,01986625 0,08760514 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 1,000 0,01986625 0,08744729 ! response to mechanical stimulus GO:0009612 60 32 1,000 0,01986625 0,08729001 ! regulation of protein import into nucleus GO:0042306 69 32 1,000 0,01986625 0,0871333 ! ovulation cycle GO:0042698 57 32 1,000 0,01986625 0,08697715 ! BMP signaling pathway GO:0030509 71 32 1,000 0,01986625 0,08682155 ! negative regulation of transport GO:0051051 164 85 2,000 0,02023242 0,08826392 ! regulation of pH GO:0006885 56 33 1,000 0,0210547 0,09168741 ! positive regulation of gene-specific transcription GO:0043193 70 33 1,000 0,0210547 0,09152426 ! triglyceride metabolic process GO:0006641 46 33 1,000 0,0210547 0,0913617 ! regulation of axonogenesis GO:0050770 86 33 1,000 0,0210547 0,09119971 ! positive regulation of neurogenesis GO:0050769 72 33 1,000 0,0210547 0,09103829 ! establishment of vesicle localization GO:0051650 67 33 1,000 0,0210547 0,09087745 ! regulation of protein transport GO:0051223 165 87 2,000 0,02150079 0,09263921 GO:0070201|regulation of establishment of protein localization, ! response to hydrogen peroxide GO:0042542 56 34 1,000 0,02227204 0,09579332 ! glial cell differentiation GO:0010001 67 34 1,000 0,02227204 0,09562496 ! post-embryonic development GO:0009791 76 34 1,000 0,02227204 0,0954572 ! cell fate specification GO:0001708 56 34 1,000 0,02227204 0,09529002 ! negative regulation of MAP kinase activity GO:0043407 78 34 1,000 0,02227204 0,09512343 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 1,000 0,02227204 0,09495742 ! regulation of DNA binding GO:0051101 167 89 2,000 0,02281178 0,09708916 ! response to inorganic substance GO:0010035 173 90 2,000 0,02348325 0,0997732 ! DNA damage checkpoint GO:0000077 78 35 1,000 0,02351783 0,09974665 ! regulation of striated muscle tissue development GO:0016202 81 35 1,000 0,02351783 0,09957378 ! telencephalon development GO:0021537 81 35 1,000 0,02351783 0,0994015 ! calcium-mediated signaling GO:0019722 67 35 1,000 0,02351783 0,09922982 ! biogenic amine biosynthetic process GO:0042401 65 35 1,000 0,02351783 0,09905874 ! vesicle localization GO:0051648 70 35 1,000 0,02351783 0,09888824 ! regulation of muscle development GO:0048634 82 36 1,000 0,02479163 0,10406522 ! mitotic sister chromatid segregation GO:0000070 63 36 1,000 0,02479163 0,10388672 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 1,000 0,02479163 0,10370884 ! negative regulation of DNA binding GO:0043392 67 36 1,000 0,02479163 0,10353156 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 1,000 0,02479163 0,10335488 ! regulation of smooth muscle cell proliferation GO:0048660 64 37 1,000 0,02609301 0,10859492 ! negative regulation of cell adhesion GO:0007162 94 37 1,000 0,02609301 0,10841024 ! sister chromatid segregation GO:0000819 65 37 1,000 0,02609301 0,10822618 ! odontogenesis GO:0042476 74 37 1,000 0,02609301 0,10804274 ! maintenance of protein location in cell GO:0032507 89 37 1,000 0,02609301 0,10785993 ! androgen receptor signaling pathway GO:0030521 81 37 1,000 0,02609301 0,10767773 ! regulation of microtubule-based process GO:0032886 86 37 1,000 0,02609301 0,10749615 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 1,000 0,02742153 0,11277912 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 1,000 0,02742153 0,11258957 ! embryonic skeletal system morphogenesis GO:0048704 68 38 1,000 0,02742153 0,11240066 ! neutral lipid metabolic process GO:0006638 54 38 1,000 0,02742153 0,11221239 GO:0006639|acylglycerol metabolic process, ! DNA integrity checkpoint GO:0031570 82 38 1,000 0,02742153 0,11202474 ! spermatid development GO:0007286 69 38 1,000 0,02742153 0,11183772 ! pigment metabolic process GO:0042440 87 38 1,000 0,02742153 0,11165133 ! response to protein stimulus GO:0051789 158 96 2,000 0,02773556 0,11274206 ! regulation of T cell activation GO:0050863 175 96 2,000 0,02773556 0,11255478 ! regulation of neuron projection development GO:0010975 102 39 1,000 0,02877677 0,11658649 ! negative regulation of binding GO:0051100 71 39 1,000 0,02877677 0,11639347 ! mitotic cell cycle checkpoint GO:0007093 76 39 1,000 0,02877677 0,11620108 ! carbohydrate homeostasis GO:0033500 59 39 1,000 0,02877677 0,11600933 GO:0042593|glucose homeostasis, ! erythrocyte homeostasis GO:0034101 75 39 1,000 0,02877677 0,11581821 ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 1,000 0,02877677 0,11562772 ! leukocyte differentiation GO:0002521 232 98 2,000 0,02923793 0,11728777 ! forebrain development GO:0030900 210 98 2,000 0,02923793 0,1170955 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 1,000 0,03015832 0,12058391 GO:0006956|complement activation, ! glycerol ether metabolic process GO:0006662 57 40 1,000 0,03015832 0,12038687 ! skeletal muscle tissue development GO:0007519 223 100 2,000 0,03078259 0,12267841 GO:0060538|skeletal muscle organ development, ! cellular amide metabolic process GO:0043603 73 41 1,000 0,03156575 0,12559466 ! gliogenesis GO:0042063 91 41 1,000 0,03156575 0,12539044 ! multicellular organismal metabolic process GO:0044236 64 41 1,000 0,03156575 0,12518688 ! monovalent inorganic cation homeostasis GO:0055067 72 41 1,000 0,03156575 0,12498399 ! maintenance of protein location GO:0045185 95 41 1,000 0,03156575 0,12478175 ! spermatid differentiation GO:0048515 73 41 1,000 0,03156575 0,12458016 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 1,000 0,03299865 0,13002533 ! ear morphogenesis GO:0042471 64 42 1,000 0,03299865 0,12981595 ! organic ether metabolic process GO:0018904 59 42 1,000 0,03299865 0,12960724 ! dorsal/ventral pattern formation GO:0009953 75 42 1,000 0,03299865 0,1293992 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 0,03344688 0,13094667 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 0,03344688 0,13073716 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,03344688 0,13052831 ! positive regulation of helicase activity GO:0051096 12 5 0,000 0,03344688 0,13032013 ! neuron fate determination GO:0048664 7 5 0,000 0,03344688 0,13011261 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,03344688 0,12990576 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 0,03344688 0,12969956 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 0,03344688 0,12949401 ! polyol transport GO:0015791 12 5 0,000 0,03344688 0,12928912 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,03344688 0,12908487 ! response to superoxide GO:0000303 10 5 0,000 0,03344688 0,12888126 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,03344688 0,1286783 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 0,03344688 0,12847598 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 0,03344688 0,12827429 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,03344688 0,12807323 ! female meiosis GO:0007143 10 5 0,000 0,03344688 0,1278728 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 0,03344688 0,127673 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,03344688 0,12747383 ! hypothalamus development GO:0021854 9 5 0,000 0,03344688 0,12727527 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 0,03344688 0,12707733 ! cobalt ion transport GO:0006824 11 5 0,000 0,03344688 0,12688 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 0,03344688 0,12668329 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 0,03344688 0,12648719 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,03344688 0,12629169 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,03344688 0,12609679 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 0,03344688 0,1259025 ! embryonic camera-type eye development GO:0031076 12 5 0,000 0,03344688 0,1257088 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,03344688 0,1255157 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,03344688 0,12532319 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 0,03344688 0,12513127 ! transposition GO:0032196 9 5 0,000 0,03344688 0,12493994 ! negative chemotaxis GO:0050919 16 5 0,000 0,03344688 0,12474919 ! positive regulation of histone modification GO:0031058 6 5 0,000 0,03344688 0,12455903 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,03344688 0,12436944 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 0,03344688 0,12418043 ! behavioral response to pain GO:0048266 10 5 0,000 0,03344688 0,12399199 ! clathrin coat assembly GO:0048268 15 5 0,000 0,03344688 0,12380412 ! Notch receptor processing GO:0007220 11 5 0,000 0,03344688 0,12361683 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,03344688 0,12343009 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 0,03344688 0,12324392 ! micturition GO:0060073 9 5 0,000 0,03344688 0,12305832 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,03344688 0,12287327 ! copulation GO:0007620 9 5 0,000 0,03344688 0,12268877 ! glial cell fate commitment GO:0021781 14 5 0,000 0,03344688 0,12250483 ! protein maturation by protein folding GO:0022417 14 5 0,000 0,03344688 0,12232144 ! bioluminescence GO:0008218 9 5 0,000 0,03344688 0,1221386 ! spermidine metabolic process GO:0008216 7 5 0,000 0,03344688 0,1219563 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,03344688 0,12177455 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,03344688 0,12159334 ! apoptotic cell clearance GO:0043277 23 5 0,000 0,03344688 0,12141266 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,03344688 0,12123253 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 0,03344688 0,12105292 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,03344688 0,12087385 ! grooming behavior GO:0007625 6 5 0,000 0,03344688 0,12069531 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 0,03344688 0,12051729 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,03344688 0,1203398 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 0,03344688 0,12016283 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,03344688 0,11998638 ! response to protozoan GO:0001562 13 5 0,000 0,03344688 0,11981044 ! lymph vessel development GO:0001945 10 5 0,000 0,03344688 0,11963502 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 0,03344688 0,11946012 ! endochondral ossification GO:0001958 17 5 0,000 0,03344688 0,11928573 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,03344688 0,11911184 ! single strand break repair GO:0000012 8 5 0,000 0,03344688 0,11893846 ! parathyroid gland development GO:0060017 14 5 0,000 0,03344688 0,11876558 ! anagen GO:0042640 7 5 0,000 0,03344688 0,11859321 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,03344688 0,11842134 ! cytokine secretion GO:0050663 15 5 0,000 0,03344688 0,11824996 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 0,03344688 0,11807908 ! ceramide catabolic process GO:0046514 7 5 0,000 0,03344688 0,11790869 ! skeletal myofibril assembly GO:0014866 12 5 0,000 0,03344688 0,11773879 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,03344688 0,11756938 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,03344688 0,11740046 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,03344688 0,11723203 ! cardiac muscle fiber development GO:0048739 12 5 0,000 0,03344688 0,11706407 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,03344688 0,1168966 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,03344688 0,1167296 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 0,03344688 0,11656308 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of RNA splicing GO:0033119 6 5 0,000 0,03344688 0,11639704 ! glycine biosynthetic process GO:0006545 7 5 0,000 0,03344688 0,11623147 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 0,03344688 0,11606637 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 0,03344688 0,11590173 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 0,03344688 0,11573757 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 0,03344688 0,11557386 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 0,03344688 0,11541062 ! polyol catabolic process GO:0046174 9 5 0,000 0,03344688 0,11524784 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 0,03344688 0,11508552 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 0,03344688 0,11492366 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 0,03344688 0,11476225 ! muscle cell migration GO:0014812 8 5 0,000 0,03344688 0,11460129 ! mitochondrial fission GO:0000266 8 5 0,000 0,03344688 0,11444079 ! sister chromatid cohesion GO:0007062 15 5 0,000 0,03344688 0,11428073 ! response to tumor necrosis factor GO:0034612 10 5 0,000 0,03344688 0,11412112 ! mRNA transcription GO:0009299 10 5 0,000 0,03344688 0,11396196 ! nerve growth factor processing GO:0032455 9 5 0,000 0,03344688 0,11380323 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 0,03344688 0,11364495 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 0,03344688 0,11348711 ! anaerobic glycolysis GO:0019642 6 5 0,000 0,03344688 0,11332971 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,03344688 0,11317274 ! monocyte activation GO:0042117 10 5 0,000 0,03344688 0,11301621 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,03344688 0,11286011 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,03344688 0,11270444 ! response to food GO:0032094 6 5 0,000 0,03344688 0,1125492 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,03344688 0,11239439 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 0,03344688 0,11224 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,03344688 0,11208604 ! forebrain neuron development GO:0021884 13 5 0,000 0,03344688 0,1119325 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,03344688 0,11177937 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 0,03344688 0,11162667 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 0,03344688 0,11147438 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,03344688 0,11132251 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,03344688 0,11117105 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 0,03344688 0,11102 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 0,03344688 0,11086936 ! lipid glycosylation GO:0030259 7 5 0,000 0,03344688 0,11071914 ! nucleobase transport GO:0015851 6 5 0,000 0,03344688 0,11056931 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,03344688 0,11041989 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 0,03344688 0,11027088 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 0,03344688 0,11012227 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 0,03344688 0,10997405 ! basic amino acid transport GO:0015802 12 5 0,000 0,03344688 0,10982624 ! cellular glucose homeostasis GO:0001678 6 5 0,000 0,03344688 0,10967882 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 0,03344688 0,1095318 ! actin nucleation GO:0045010 11 5 0,000 0,03344688 0,10938517 ! depurination GO:0045007 5 5 0,000 0,03344688 0,10923893 ! depyrimidination GO:0045008 10 5 0,000 0,03344688 0,10909309 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,03344688 0,10894763 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,03344688 0,10880256 ! G2/M transition checkpoint GO:0031576 8 5 0,000 0,03344688 0,10865787 GO:0031572|G2/M transition DNA damage checkpoint, ! zinc ion homeostasis GO:0055069 9 5 0,000 0,03344688 0,10851357 GO:0006882|cellular zinc ion homeostasis, ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 0,03344688 0,10836966 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,03344688 0,10822612 ! activated T cell proliferation GO:0050798 16 5 0,000 0,03344688 0,10808297 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,03344688 0,10794019 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 0,03344688 0,10779779 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,03344688 0,10765576 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,03344688 0,10751411 ! gamma-delta T cell activation GO:0046629 6 5 0,000 0,03344688 0,10737283 ! response to arsenic GO:0046685 11 5 0,000 0,03344688 0,10723192 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 0,03344688 0,10709138 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,03344688 0,10695121 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 0,03344688 0,1068114 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 0,03344688 0,10667196 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 0,03344688 0,10653288 ! response to mercury ion GO:0046689 8 5 0,000 0,03344688 0,10639417 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 0,03344688 0,10625582 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 0,03344688 0,10611782 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 0,03344688 0,10598018 ! bile acid biosynthetic process GO:0006699 7 5 0,000 0,03344688 0,1058429 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 0,03344688 0,10570598 ! ganglioside catabolic process GO:0006689 12 5 0,000 0,03344688 0,10556941 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,03344688 0,10543319 ! decidualization GO:0046697 11 5 0,000 0,03344688 0,10529732 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 0,03344688 0,1051618 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 0,03344688 0,10502663 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 0,03344688 0,10489181 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 0,03344688 0,10475734 ! embryonic cleavage GO:0040016 6 5 0,000 0,03344688 0,1046232 ! peroxisome fission GO:0016559 5 5 0,000 0,03344688 0,10448941 ! histone demethylation GO:0016577 13 5 0,000 0,03344688 0,10435597 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 0,03344688 0,10422286 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 0,03344688 0,10409009 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,03344688 0,10395766 ! metaphase plate congression GO:0051310 7 5 0,000 0,03344688 0,10382557 ! regulation of sterol transport GO:0032371 7 5 0,000 0,03344688 0,10369381 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,03344688 0,10356239 ! enteric nervous system development GO:0048484 8 5 0,000 0,03344688 0,10343129 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 0,03344688 0,10330053 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 0,03344688 0,1031701 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 0,03344688 0,10304 ! muscle cell proliferation GO:0033002 12 5 0,000 0,03344688 0,10291023 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,03344688 0,10278078 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 0,03344688 0,10265166 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 0,03344688 0,10252286 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,03344688 0,10239439 ! metaphase GO:0051323 11 5 0,000 0,03344688 0,10226624 ! melatonin biosynthetic process GO:0030187 7 5 0,000 0,03344688 0,1021384 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 0,03344688 0,10201089 ! cellular response to nutrient GO:0031670 8 5 0,000 0,03344688 0,10188369 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,03344688 0,10175681 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 0,03344688 0,10163025 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 0,03344688 0,101504 ! regulation of hair follicle development GO:0051797 10 5 0,000 0,03344688 0,10137807 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 0,03344688 0,10125244 ! response to redox state GO:0051775 6 5 0,000 0,03344688 0,10112713 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 0,03344688 0,10100213 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 0,03344688 0,10087743 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,03344688 0,10075305 ! brown fat cell differentiation GO:0050873 7 5 0,000 0,03344688 0,10062897 ! regulation of telomerase activity GO:0051972 7 5 0,000 0,03344688 0,10050519 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,03344688 0,10038172 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 0,03344688 0,10025855 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,03344688 0,10013569 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 0,03344688 0,10001312 ! striatum development GO:0021756 14 5 0,000 0,03344688 0,09989086 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 0,03344688 0,09976889 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,03344688 0,09964722 ! glial cell migration GO:0008347 10 5 0,000 0,03344688 0,09952585 ! neural plate morphogenesis GO:0001839 7 5 0,000 0,03344688 0,09940477 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,03344688 0,09928399 ! T cell activation during immune response GO:0002286 9 5 0,000 0,03344688 0,0991635 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,03344688 0,0990433 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,03344688 0,09892339 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 0,03344688 0,09880377 ! neuroprotection GO:0043526 8 5 0,000 0,03344688 0,09868445 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,03344688 0,09856541 ! regulation of sensory perception GO:0051931 8 5 0,000 0,03344688 0,09844665 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,03344688 0,09832819 GO:0046831|regulation of RNA export from nucleus, ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 0,03344688 0,09821 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 0,03344688 0,0980921 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,03344688 0,09797449 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 0,03344688 0,09785715 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,03344688 0,0977401 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 0,03344688 0,09762332 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 0,03344688 0,09750683 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,03344688 0,09739061 ! spindle assembly GO:0051225 6 5 0,000 0,03344688 0,09727467 ! receptor biosynthetic process GO:0032800 7 5 0,000 0,03344688 0,097159 ! protein palmitoylation GO:0018345 12 5 0,000 0,03344688 0,09704361 ! drug metabolic process GO:0017144 7 5 0,000 0,03344688 0,0969285 ! organ regeneration GO:0031100 7 5 0,000 0,03344688 0,09681365 ! carnitine metabolic process GO:0009437 8 5 0,000 0,03344688 0,09669908 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,03344688 0,09658478 ! positive regulation of transcription factor activity GO:0051091 71 43 1,000 0,03445662 0,09938315 GO:0090047|positive regulation of transcription regulator activity, ! epithelial cell differentiation GO:0030855 83 43 1,000 0,03445662 0,09926595 ! calcium-dependent cell-cell adhesion GO:0016339 56 43 1,000 0,03445662 0,09914903 ! glucose transport GO:0015758 66 43 1,000 0,03445662 0,09903239 ! segmentation GO:0035282 78 43 1,000 0,03445662 0,09891601 ! negative regulation of protein complex disassembly GO:0043242 113 44 1,000 0,03593926 0,10305118 ! hexose transport GO:0008645 68 44 1,000 0,03593926 0,10293037 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 1,000 0,03593926 0,10280985 ! receptor-mediated endocytosis GO:0006898 98 45 1,000 0,03744616 0,10699529 ! keratinocyte differentiation GO:0030216 81 45 1,000 0,03744616 0,10687029 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,04000135 0,11402951 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,04000135 0,11389661 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 0,04000135 0,11376402 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 0,04000135 0,11363173 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,04000135 0,11349976 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 0,04000135 0,11336809 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 0,04000135 0,11323672 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,04000135 0,11310566 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 0,04000135 0,1129749 ! response to oxygen radical GO:0000305 11 6 0,000 0,04000135 0,11284445 ! positive regulation of axon extension GO:0045773 13 6 0,000 0,04000135 0,11271429 ! myoblast cell fate commitment GO:0048625 18 6 0,000 0,04000135 0,11258444 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 0,04000135 0,11245488 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 0,04000135 0,11232562 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,04000135 0,11219666 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,04000135 0,11206799 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 0,04000135 0,11193962 ! forebrain regionalization GO:0021871 9 6 0,000 0,04000135 0,11181155 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,04000135 0,11168376 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,04000135 0,11155627 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 0,04000135 0,11142907 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,04000135 0,11130215 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 0,04000135 0,11117553 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,04000135 0,1110492 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 0,04000135 0,11092315 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 0,04000135 0,11079738 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,04000135 0,1106719 ! malate metabolic process GO:0006108 13 6 0,000 0,04000135 0,11054671 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 0,04000135 0,1104218 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 0,04000135 0,11029717 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 0,04000135 0,11017282 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 0,04000135 0,11004875 ! protein refolding GO:0042026 15 6 0,000 0,04000135 0,10992496 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,04000135 0,10980145 ! opsonization GO:0008228 8 6 0,000 0,04000135 0,10967822 ! mating behavior GO:0007617 7 6 0,000 0,04000135 0,10955526 ! erythrocyte maturation GO:0043249 8 6 0,000 0,04000135 0,10943258 ! embryonic hemopoiesis GO:0035162 16 6 0,000 0,04000135 0,10931017 ! protein amino acid dealkylation GO:0008214 15 6 0,000 0,04000135 0,10918804 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 0,04000135 0,10906617 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 0,04000135 0,10894458 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,04000135 0,10882326 ! response to interferon-gamma GO:0034341 16 6 0,000 0,04000135 0,10870222 ! toxin metabolic process GO:0009404 11 6 0,000 0,04000135 0,10858144 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,04000135 0,10846092 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 0,04000135 0,10834068 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 0,04000135 0,1082207 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 0,04000135 0,10810099 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 13 6 0,000 0,04000135 0,10798154 ! cGMP-mediated signaling GO:0019934 14 6 0,000 0,04000135 0,10786235 ! dorsal spinal cord development GO:0021516 10 6 0,000 0,04000135 0,10774343 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,04000135 0,10762477 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 0,04000135 0,10750637 ! thymic T cell selection GO:0045061 16 6 0,000 0,04000135 0,10738823 ! sphingoid catabolic process GO:0046521 8 6 0,000 0,04000135 0,10727035 ! protein lipoylation GO:0009249 10 6 0,000 0,04000135 0,10715273 ! transepithelial chloride transport GO:0030321 12 6 0,000 0,04000135 0,10703537 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 0,04000135 0,10691826 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 0,04000135 0,10680141 ! glutamate catabolic process GO:0006538 12 6 0,000 0,04000135 0,10668482 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 0,04000135 0,10656848 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,04000135 0,10645239 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 0,04000135 0,10633655 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,04000135 0,10622097 ! hyperosmotic response GO:0006972 10 6 0,000 0,04000135 0,10610564 ! L-serine biosynthetic process GO:0006564 7 6 0,000 0,04000135 0,10599055 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 0,04000135 0,10587572 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 0,04000135 0,10576114 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,04000135 0,1056468 ! urea metabolic process GO:0019627 7 6 0,000 0,04000135 0,10553271 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,04000135 0,10541887 ! neutrophil activation GO:0042119 7 6 0,000 0,04000135 0,10530527 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,04000135 0,10519192 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 0,04000135 0,10507881 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,04000135 0,10496594 ! paraxial mesoderm development GO:0048339 16 6 0,000 0,04000135 0,10485332 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 0,04000135 0,10474093 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,04000135 0,10462879 ! neuron apoptosis GO:0051402 15 6 0,000 0,04000135 0,10451689 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,04000135 0,10440523 ! T cell mediated immunity GO:0002456 17 6 0,000 0,04000135 0,1042938 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,04000135 0,10418261 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 0,04000135 0,10407166 ! carnitine transport GO:0015879 10 6 0,000 0,04000135 0,10396095 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,04000135 0,10385047 ! positive regulation of exocytosis GO:0045921 11 6 0,000 0,04000135 0,10374022 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 0,04000135 0,10363021 ! early endosome to late endosome transport GO:0045022 16 6 0,000 0,04000135 0,10352044 ! 5S class rRNA transcription GO:0042791 13 6 0,000 0,04000135 0,10341089 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! neuronal ion channel clustering GO:0045161 15 6 0,000 0,04000135 0,10330158 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 0,04000135 0,10319249 ! sodium ion homeostasis GO:0055078 12 6 0,000 0,04000135 0,10308364 ! protein targeting to lysosome GO:0006622 12 6 0,000 0,04000135 0,10297502 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,04000135 0,10286662 ! interaction with symbiont GO:0051702 14 6 0,000 0,04000135 0,10275846 ! regulation of dendrite development GO:0050773 16 6 0,000 0,04000135 0,10265052 ! peptidyl-arginine modification GO:0018195 13 6 0,000 0,04000135 0,1025428 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 0,04000135 0,10243532 ! response to exogenous dsRNA GO:0043330 13 6 0,000 0,04000135 0,10232805 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 0,04000135 0,10222102 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,04000135 0,1021142 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 0,04000135 0,10200761 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,04000135 0,10190124 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 0,04000135 0,1017951 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,04000135 0,10168917 ! nucleoside catabolic process GO:0009164 10 6 0,000 0,04000135 0,10158346 ! hair follicle maturation GO:0048820 8 6 0,000 0,04000135 0,10147798 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,04000135 0,10137271 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 0,04000135 0,10126766 ! response to pheromone GO:0019236 6 6 0,000 0,04000135 0,10116283 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 0,04000135 0,10105821 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 0,04000135 0,10095381 ! base conversion or substitution editing GO:0016553 6 6 0,000 0,04000135 0,10084963 ! subpallium development GO:0021544 15 6 0,000 0,04000135 0,10074566 ! neural tube patterning GO:0021532 8 6 0,000 0,04000135 0,10064191 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 0,04000135 0,10053837 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 0,04000135 0,10043504 ! maintenance of organ identity GO:0048496 9 6 0,000 0,04000135 0,10033192 ! G2 phase GO:0051319 16 6 0,000 0,04000135 0,10022902 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 0,04000135 0,10012632 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 0,04000135 0,10002384 ! oxygen homeostasis GO:0032364 10 6 0,000 0,04000135 0,09992157 ! establishment of planar polarity GO:0001736 7 6 0,000 0,04000135 0,0998195 ! regulation of mast cell activation GO:0033003 13 6 0,000 0,04000135 0,09971764 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,04000135 0,099616 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 0,04000135 0,09951455 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,04000135 0,09941332 ! receptor internalization GO:0031623 11 6 0,000 0,04000135 0,09931229 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 0,04000135 0,09921146 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 0,04000135 0,09911084 ! neutrophil homeostasis GO:0001780 11 6 0,000 0,04000135 0,09901043 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,04000135 0,09891021 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 0,04000135 0,0988102 ! protein deubiquitination GO:0016579 16 6 0,000 0,04000135 0,0987104 ! protein destabilization GO:0031648 9 6 0,000 0,04000135 0,09861079 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 0,04000135 0,09851138 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,04000135 0,09841218 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 0,04000135 0,09831317 ! regulation of viral transcription GO:0046782 11 6 0,000 0,04000135 0,09821436 ! progesterone metabolic process GO:0042448 12 6 0,000 0,04000135 0,09811575 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 0,04000135 0,09801734 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 0,04000135 0,09791913 ! determination of adult lifespan GO:0008340 17 6 0,000 0,04000135 0,09782111 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 0,04000135 0,09772329 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 0,04000135 0,09762567 ! neural plate development GO:0001840 9 6 0,000 0,04000135 0,09752824 ! catecholamine transport GO:0051937 9 6 0,000 0,04000135 0,097431 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 0,04000135 0,09733396 ! sensory cilium assembly GO:0035058 10 6 0,000 0,04000135 0,09723711 ! organ or tissue specific immune response GO:0002251 8 6 0,000 0,04000135 0,09714045 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 0,04000135 0,09704398 ! maternal placenta development GO:0001893 12 6 0,000 0,04000135 0,09694771 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 0,04000135 0,09685163 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,04000135 0,09675573 ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 0,04000135 0,09666003 ! positive regulation of coagulation GO:0050820 13 6 0,000 0,04000135 0,09656452 ! cellular anion homeostasis GO:0030002 11 6 0,000 0,04000135 0,09646919 GO:0055081|anion homeostasis, ! positive regulation of adenylate cyclase activity GO:0045762 104 48 1,000 0,04210854 0,10145086 ! regulation of JAK-STAT cascade GO:0046425 76 48 1,000 0,04210854 0,10135091 ! positive regulation of DNA binding GO:0043388 83 48 1,000 0,04210854 0,10125115 ! JAK-STAT cascade GO:0007259 82 48 1,000 0,04210854 0,10115159 ! detection of stimulus involved in sensory perception GO:0050906 75 49 1,000 0,04370861 0,10489207 ! positive regulation of cyclase activity GO:0031281 106 49 1,000 0,04370861 0,10478914 ! positive regulation of lyase activity GO:0051349 107 50 1,000 0,04533101 0,10857222 ! epidermal cell differentiation GO:0009913 87 50 1,000 0,04533101 0,10846588 ! immunoglobulin mediated immune response GO:0016064 89 50 1,000 0,04533101 0,10835975 GO:0019724|B cell mediated immunity, ! tRNA transcription GO:0009304 17 7 0,000 0,04651155 0,11107304 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 0,04651155 0,11096457 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 0,04651155 0,11085632 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,04651155 0,11074827 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,04651155 0,11064043 ! sleep GO:0030431 16 7 0,000 0,04651155 0,1105328 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,04651155 0,11042539 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 0,04651155 0,11031818 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,04651155 0,11021118 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,04651155 0,11010438 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,04651155 0,1099978 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,04651155 0,10989142 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,04651155 0,10978524 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,04651155 0,10967927 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,04651155 0,1095735 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,04651155 0,10946794 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,04651155 0,10936258 ! SMAD protein complex assembly GO:0007183 13 7 0,000 0,04651155 0,10925743 ! glycolipid transport GO:0046836 11 7 0,000 0,04651155 0,10915247 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,04651155 0,10904772 GO:0051923|sulfation, ! neuron adhesion GO:0007158 14 7 0,000 0,04651155 0,10894317 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,04651155 0,10883882 ! establishment of tissue polarity GO:0007164 8 7 0,000 0,04651155 0,10873466 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 0,04651155 0,10863071 ! mRNA stabilization GO:0048255 18 7 0,000 0,04651155 0,10852696 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 0,04651155 0,1084234 ! fibril organization GO:0043206 17 7 0,000 0,04651155 0,10832004 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 0,04651155 0,10821688 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,04651155 0,10811391 ! lipoprotein transport GO:0042953 14 7 0,000 0,04651155 0,10801114 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,04651155 0,10790857 ! rhythmic behavior GO:0007622 17 7 0,000 0,04651155 0,10780619 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 0,04651155 0,107704 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 0,04651155 0,10760201 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,04651155 0,10750021 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 0,04651155 0,1073986 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,04651155 0,10729719 ! regulation of odontogenesis GO:0042481 14 7 0,000 0,04651155 0,10719597 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,04651155 0,10709493 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 0,04651155 0,10699409 ! mechanosensory behavior GO:0007638 16 7 0,000 0,04651155 0,10689344 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 0,04651155 0,10679297 ! positive regulation of isotype switching GO:0045830 17 7 0,000 0,04651155 0,1066927 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 0,04651155 0,10659261 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,04651155 0,10649271 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,04651155 0,106393 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,04651155 0,10629347 ! spinal cord patterning GO:0021511 14 7 0,000 0,04651155 0,10619413 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 0,04651155 0,10609498 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,04651155 0,10599601 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,04651155 0,10589723 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 0,04651155 0,10579862 ! cysteine metabolic process GO:0006534 13 7 0,000 0,04651155 0,10570021 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 0,04651155 0,10560197 ! ovulation GO:0030728 10 7 0,000 0,04651155 0,10550392 ! adenohypophysis development GO:0021984 11 7 0,000 0,04651155 0,10540605 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 0,04651155 0,10530836 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 0,04651155 0,10521085 ! microtubule nucleation GO:0007020 21 7 0,000 0,04651155 0,10511353 ! proline biosynthetic process GO:0006561 10 7 0,000 0,04651155 0,10501638 ! tryptophan metabolic process GO:0006568 11 7 0,000 0,04651155 0,10491941 ! thyroid hormone generation GO:0006590 13 7 0,000 0,04651155 0,10482262 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 0,04651155 0,10472601 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,04651155 0,10462958 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,04651155 0,10453332 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,04651155 0,10443725 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,04651155 0,10434134 ! galactose metabolic process GO:0006012 13 7 0,000 0,04651155 0,10424562 ! vesicle fusion GO:0006906 20 7 0,000 0,04651155 0,10415007 ! response to dietary excess GO:0002021 8 7 0,000 0,04651155 0,10405469 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,04651155 0,10395949 ! intracellular pH reduction GO:0051452 13 7 0,000 0,04651155 0,10386446 GO:0045851|pH reduction, ! melanosome organization GO:0032438 10 7 0,000 0,04651155 0,10376961 ! nucleoside transport GO:0015858 11 7 0,000 0,04651155 0,10367493 ! nucleoside salvage GO:0043174 11 7 0,000 0,04651155 0,10358042 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 0,04651155 0,10348609 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,04651155 0,10339192 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 0,04651155 0,10329793 ! parturition GO:0007567 16 7 0,000 0,04651155 0,10320411 ! rRNA modification GO:0000154 14 7 0,000 0,04651155 0,10311046 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,04651155 0,10301697 ! spindle checkpoint GO:0031577 16 7 0,000 0,04651155 0,10292366 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 0,04651155 0,10283052 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,04651155 0,10273754 ! monocyte differentiation GO:0030224 16 7 0,000 0,04651155 0,10264474 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,04651155 0,1025521 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,04651155 0,10245962 GO:0046676|negative regulation of insulin secretion, ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,04651155 0,10236732 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,04651155 0,10227518 ! fibrinolysis GO:0042730 11 7 0,000 0,04651155 0,1021832 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 0,000 0,04651155 0,1020914 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,04651155 0,10199975 ! eating behavior GO:0042755 8 7 0,000 0,04651155 0,10190827 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,04651155 0,10181696 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 0,04651155 0,1017258 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 0,04651155 0,10163481 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,04651155 0,10154399 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 0,04651155 0,10145332 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,04651155 0,10136282 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 0,04651155 0,10127248 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 0,04651155 0,1011823 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 0,04651155 0,10109228 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,04651155 0,10100242 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 0,04651155 0,10091272 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,04651155 0,10082318 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,04651155 0,1007338 ! histone ubiquitination GO:0016574 9 7 0,000 0,04651155 0,10064457 ! regulation of meiosis GO:0040020 12 7 0,000 0,04651155 0,10055551 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 0,04651155 0,1004666 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 0,04651155 0,10037785 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,04651155 0,10028925 ! membrane to membrane docking GO:0022614 14 7 0,000 0,04651155 0,10020081 ! transcription termination GO:0006353 14 7 0,000 0,04651155 0,10011253 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,04651155 0,1000244 ! anaphase GO:0051322 18 7 0,000 0,04651155 0,09993643 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 0,04651155 0,09984861 ! axonal fasciculation GO:0007413 19 7 0,000 0,04651155 0,09976095 ! negative regulation of nuclear division GO:0051784 15 7 0,000 0,04651155 0,09967344 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 0,04651155 0,09958609 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,04651155 0,09949888 GO:0015991|ATP hydrolysis coupled proton transport, ! diuresis GO:0030146 12 7 0,000 0,04651155 0,09941183 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,04651155 0,09932493 ! thiamin metabolic process GO:0006772 7 7 0,000 0,04651155 0,09923819 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,04651155 0,09915159 ! antibiotic transport GO:0042891 9 7 0,000 0,04651155 0,09906515 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,04651155 0,09897885 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 0,04651155 0,09889271 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 0,04651155 0,09880672 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 0,04651155 0,09872087 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,04651155 0,09863518 ! melanin biosynthetic process GO:0042438 10 7 0,000 0,04651155 0,09854963 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 0,04651155 0,09846423 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,04651155 0,09837898 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 0,04651155 0,09829388 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,04651155 0,09820892 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 0,04651155 0,09812411 ! endosome to lysosome transport GO:0008333 12 7 0,000 0,04651155 0,09803945 ! protein modification by small protein removal GO:0070646 19 7 0,000 0,04651155 0,09795493 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 0,04651155 0,09787056 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,04651155 0,09778634 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 0,04651155 0,09770226 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,04651155 0,09761832 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,04651155 0,09753453 ! muscle adaptation GO:0043500 13 7 0,000 0,04651155 0,09745088 ! embryonic heart tube development GO:0035050 14 7 0,000 0,04651155 0,09736737 ! retina homeostasis GO:0001895 12 7 0,000 0,04651155 0,09728401 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 0,04651155 0,09720079 ! protein amino acid prenylation GO:0018346 19 7 0,000 0,04651155 0,09711771 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 0,04651155 0,09703478 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 0,04651155 0,09695198 ! regulation of cell projection organization GO:0031344 135 51 1,000 0,04697538 0,09783533 ! detection of abiotic stimulus GO:0009582 80 51 1,000 0,04697538 0,097752 ! positive regulation of binding GO:0051099 88 52 1,000 0,04864133 0,10113258 ! regulation of protein complex disassembly GO:0043244 127 52 1,000 0,04864133 0,10104658 ! histone modification GO:0016570 104 52 1,000 0,04864133 0,10096073 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 1,000 0,04864133 0,10087503 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 1,000 0,05032852 0,10428548 ! cartilage development GO:0051216 99 53 1,000 0,05032852 0,1041971 ! regulation of translational initiation GO:0006446 87 54 1,000 0,05203657 0,10764212 ! activation of phospholipase C activity GO:0007202 110 54 1,000 0,05203657 0,10755105 GO:0010863|positive regulation of phospholipase C activity, ! embryonic skeletal system development GO:0048706 101 54 1,000 0,05203657 0,10746014 ! covalent chromatin modification GO:0016569 115 54 1,000 0,05203657 0,10736938 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,05297779 0,10921919 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,05297779 0,1091271 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 0,05297779 0,10903517 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,05297779 0,10894339 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,05297779 0,10885176 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,05297779 0,10876029 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,05297779 0,10866897 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,05297779 0,10857781 ! meiotic prophase I GO:0007128 14 8 0,000 0,05297779 0,10848679 ! response to zinc ion GO:0010043 12 8 0,000 0,05297779 0,10839593 ! regulation of lipid kinase activity GO:0043550 17 8 0,000 0,05297779 0,10830522 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,05297779 0,10821467 ! oligopeptide transport GO:0006857 16 8 0,000 0,05297779 0,10812426 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,05297779 0,10803401 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,05297779 0,10794391 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,05297779 0,10785395 ! signal peptide processing GO:0006465 12 8 0,000 0,05297779 0,10776415 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,05297779 0,1076745 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,05297779 0,10758499 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,05297779 0,10749563 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,05297779 0,10740643 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,05297779 0,10731737 ! estrogen metabolic process GO:0008210 17 8 0,000 0,05297779 0,10722845 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,05297779 0,10713969 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,05297779 0,10705107 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,05297779 0,1069626 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,05297779 0,10687427 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,05297779 0,10678609 ! reflex GO:0060004 17 8 0,000 0,05297779 0,10669806 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,05297779 0,10661017 ! hemoglobin metabolic process GO:0020027 14 8 0,000 0,05297779 0,10652242 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,05297779 0,10643482 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,05297779 0,10634737 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,05297779 0,10626005 ! histidine catabolic process GO:0006548 10 8 0,000 0,05297779 0,10617288 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,05297779 0,10608586 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,05297779 0,10599897 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,05297779 0,10591223 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,05297779 0,10582563 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,05297779 0,10573917 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,05297779 0,10565285 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,05297779 0,10556668 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,05297779 0,10548064 ! macrophage activation GO:0042116 13 8 0,000 0,05297779 0,10539474 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,05297779 0,10530899 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! positive regulation of insulin secretion GO:0032024 17 8 0,000 0,05297779 0,10522337 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,05297779 0,10513789 ! purine salvage GO:0043101 12 8 0,000 0,05297779 0,10505255 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,05297779 0,10496735 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,05297779 0,10488229 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,05297779 0,10479736 ! osteoblast development GO:0002076 17 8 0,000 0,05297779 0,10471258 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,05297779 0,10462793 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,05297779 0,10454341 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,05297779 0,10445903 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,05297779 0,10437479 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,05297779 0,10429069 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,05297779 0,10420672 ! intermediate filament organization GO:0045109 12 8 0,000 0,05297779 0,10412288 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,05297779 0,10403918 ! cellular extravasation GO:0045123 13 8 0,000 0,05297779 0,10395562 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,05297779 0,10387219 ! response to antibiotic GO:0046677 11 8 0,000 0,05297779 0,10378889 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,05297779 0,10370572 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,05297779 0,10362269 ! DNA topological change GO:0006265 12 8 0,000 0,05297779 0,10353979 ! response to tropane GO:0014073 15 8 0,000 0,05297779 0,10345703 GO:0042220|response to cocaine, ! melanosome transport GO:0032402 13 8 0,000 0,05297779 0,1033744 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,05297779 0,10329189 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,05297779 0,10320952 ! mast cell activation GO:0045576 14 8 0,000 0,05297779 0,10312729 ! multicellular organismal aging GO:0010259 20 8 0,000 0,05297779 0,10304518 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 0,05297779 0,1029632 ! gas homeostasis GO:0033483 14 8 0,000 0,05297779 0,10288135 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,05297779 0,10279964 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,05297779 0,10271805 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,05297779 0,10263659 ! nucleosome disassembly GO:0006337 14 8 0,000 0,05297779 0,10255526 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,05297779 0,10247406 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 0,05297779 0,10239299 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,05297779 0,10231205 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,05297779 0,10223124 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,05297779 0,10215055 ! intracellular lipid transport GO:0032365 16 8 0,000 0,05297779 0,10206999 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,05297779 0,10198955 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,05297779 0,10190925 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 0,05297779 0,10182907 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,05297779 0,10174901 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 0,05297779 0,10166908 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,05297779 0,10158928 ! hormone catabolic process GO:0042447 17 8 0,000 0,05297779 0,1015096 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,05297779 0,10143005 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,05297779 0,10135062 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,05297779 0,10127132 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,05297779 0,10119214 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,05297779 0,10111308 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,05297779 0,10103415 ! adult feeding behavior GO:0008343 10 8 0,000 0,05297779 0,10095534 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,05297779 0,10087665 ! ATP catabolic process GO:0006200 11 8 0,000 0,05297779 0,10079809 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,05297779 0,10071964 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,05297779 0,10064132 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,05297779 0,10056313 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,05297779 0,10048505 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,05297779 0,10040709 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,05297779 0,10032926 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,05297779 0,10025154 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,05297779 0,10017395 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,05297779 0,10009648 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 0,05297779 0,10001912 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,05297779 0,09994189 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 0,05297779 0,09986477 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,05297779 0,09978777 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,05297779 0,0997109 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 0,05297779 0,09963414 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 0,05297779 0,0995575 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,05297779 0,09948097 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,05297779 0,09940457 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 0,05297779 0,09932828 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 0,05297779 0,0992521 ! positive regulation of phospholipase activity GO:0010518 111 55 1,000 0,05376513 0,10064997 ! cell maturation GO:0048469 107 55 1,000 0,05376513 0,10057291 ! skeletal muscle fiber development GO:0048741 130 56 1,000 0,05551384 0,10376459 ! negative regulation of cytoskeleton organization GO:0051494 139 56 1,000 0,05551384 0,10368526 ! RNA elongation GO:0006354 90 56 1,000 0,05551384 0,10360605 ! muscle fiber development GO:0048747 131 57 1,000 0,05728236 0,10682505 ! regulation of phospholipase activity GO:0010517 113 57 1,000 0,05728236 0,10674356 ! positive regulation of organelle organization GO:0010638 108 58 1,000 0,05907034 0,10999149 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 1,000 0,05907034 0,10990772 ! positive regulation of lipase activity GO:0060193 115 58 1,000 0,05907034 0,10982407 ! axon extension GO:0048675 16 9 0,000 0,05940036 0,11035367 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,05940036 0,11026981 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 0,05940036 0,11018609 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,05940036 0,11010249 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,05940036 0,11001901 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,05940036 0,10993566 ! reproductive behavior GO:0019098 22 9 0,000 0,05940036 0,10985244 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 0,05940036 0,10976935 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 0,05940036 0,10968638 ! UTP metabolic process GO:0046051 10 9 0,000 0,05940036 0,10960353 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,05940036 0,10952081 ! induction of positive chemotaxis GO:0050930 17 9 0,000 0,05940036 0,10943822 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,05940036 0,10935575 ! regulation of histone modification GO:0031056 14 9 0,000 0,05940036 0,1092734 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,05940036 0,10919118 ! equilibrioception GO:0050957 20 9 0,000 0,05940036 0,10910908 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,05940036 0,1090271 ! chemosensory behavior GO:0007635 21 9 0,000 0,05940036 0,10894525 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,05940036 0,10886352 ! leukocyte degranulation GO:0043299 16 9 0,000 0,05940036 0,10878192 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,05940036 0,10870043 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,05940036 0,10861907 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,05940036 0,10853783 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,05940036 0,10845671 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,05940036 0,10837571 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,05940036 0,10829483 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,05940036 0,10821408 ! protein targeting to ER GO:0045047 25 9 0,000 0,05940036 0,10813344 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,05940036 0,10805292 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 0,05940036 0,10797253 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,05940036 0,10789225 ! glycine catabolic process GO:0006546 15 9 0,000 0,05940036 0,10781209 ! endosome organization GO:0007032 20 9 0,000 0,05940036 0,10773205 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,05940036 0,10765213 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,05940036 0,10757233 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,05940036 0,10749265 ! mannose metabolic process GO:0006013 13 9 0,000 0,05940036 0,10741308 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,05940036 0,10733364 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,05940036 0,10725431 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 0,05940036 0,10717509 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,05940036 0,107096 ! receptor clustering GO:0043113 20 9 0,000 0,05940036 0,10701702 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,05940036 0,10693815 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,05940036 0,10685941 ! retinol metabolic process GO:0042572 20 9 0,000 0,05940036 0,10678078 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,05940036 0,10670226 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,05940036 0,10662386 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,05940036 0,10654558 ! macrophage differentiation GO:0030225 15 9 0,000 0,05940036 0,10646741 ! oligodendrocyte development GO:0014003 11 9 0,000 0,05940036 0,10638935 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 0,05940036 0,10631141 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,05940036 0,10623358 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,05940036 0,10615587 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,05940036 0,10607827 ! response to amine stimulus GO:0014075 13 9 0,000 0,05940036 0,10600079 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,05940036 0,10592341 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,05940036 0,10584615 ! erythrocyte development GO:0048821 17 9 0,000 0,05940036 0,10576901 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,05940036 0,10569197 ! renal water homeostasis GO:0003091 15 9 0,000 0,05940036 0,10561505 ! postreplication repair GO:0006301 25 9 0,000 0,05940036 0,10553824 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,05940036 0,10546154 ! icosanoid secretion GO:0032309 15 9 0,000 0,05940036 0,10538495 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,05940036 0,10530847 GO:0021696|cerebellar cortex morphogenesis, ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,05940036 0,10523211 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,05940036 0,10515585 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,05940036 0,10507971 ! sterol catabolic process GO:0016127 14 9 0,000 0,05940036 0,10500367 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,05940036 0,10492775 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,05940036 0,10485193 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,05940036 0,10477623 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,05940036 0,10470063 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 0,05940036 0,10462514 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,05940036 0,10454977 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 0,05940036 0,1044745 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,05940036 0,10439933 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,05940036 0,10432428 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,05940036 0,10424934 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,05940036 0,1041745 ! purine base metabolic process GO:0006144 25 9 0,000 0,05940036 0,10409977 ! pigment granule transport GO:0051904 17 9 0,000 0,05940036 0,10402514 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,05940036 0,10395063 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,05940036 0,10387622 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,05940036 0,10380191 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,05940036 0,10372772 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,05940036 0,10365363 ! mitochondrion localization GO:0051646 18 9 0,000 0,05940036 0,10357964 ! lipid modification GO:0030258 112 60 1,000 0,06270329 0,10926115 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,06577955 0,11453987 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,06577955 0,11445829 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,06577955 0,11437682 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,06577955 0,11429547 ! associative learning GO:0008306 21 10 0,000 0,06577955 0,11421424 ! positive regulation of B cell proliferation GO:0030890 18 10 0,000 0,06577955 0,11413312 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,06577955 0,11405212 ! phosphate transport GO:0006817 24 10 0,000 0,06577955 0,11397123 ! cell volume homeostasis GO:0006884 17 10 0,000 0,06577955 0,11389046 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,06577955 0,1138098 ! CTP metabolic process GO:0046036 11 10 0,000 0,06577955 0,11372925 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 0,06577955 0,11364882 ! GTP metabolic process GO:0046039 11 10 0,000 0,06577955 0,11356851 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,06577955 0,1134883 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,06577955 0,11340821 ! social behavior GO:0035176 29 10 0,000 0,06577955 0,11332823 ! smoothened signaling pathway GO:0007224 18 10 0,000 0,06577955 0,11324837 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,06577955 0,11316862 ! androgen metabolic process GO:0008209 17 10 0,000 0,06577955 0,11308898 ! phospholipid efflux GO:0033700 19 10 0,000 0,06577955 0,11300945 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,06577955 0,11293003 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,06577955 0,11285073 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,06577955 0,11277153 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,06577955 0,11269245 ! lung alveolus development GO:0048286 26 10 0,000 0,06577955 0,11261348 ! pathogenesis GO:0009405 17 10 0,000 0,06577955 0,11253462 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,06577955 0,11245587 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 0,06577955 0,11237723 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,06577955 0,1122987 ! endoderm development GO:0007492 18 10 0,000 0,06577955 0,11222028 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,06577955 0,11214197 ! arginine catabolic process GO:0006527 17 10 0,000 0,06577955 0,11206376 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,06577955 0,11198567 ! proline metabolic process GO:0006560 13 10 0,000 0,06577955 0,11190769 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,06577955 0,11182981 GO:0005978|glycogen biosynthetic process, ! V(D)J recombination GO:0033151 34 10 0,000 0,06577955 0,11175204 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,06577955 0,11167438 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,06577955 0,11159683 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,06577955 0,11151939 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,06577955 0,11144205 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,06577955 0,11136482 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,06577955 0,1112877 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,06577955 0,11121068 ! ruffle organization GO:0031529 17 10 0,000 0,06577955 0,11113377 ! epithelial cell development GO:0002064 21 10 0,000 0,06577955 0,11105697 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,06577955 0,11098027 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,06577955 0,11090368 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,06577955 0,1108272 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,06577955 0,11075082 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,06577955 0,11067454 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,06577955 0,11059837 GO:0030204|chondroitin sulfate metabolic process, ! segment specification GO:0007379 15 10 0,000 0,06577955 0,11052231 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,06577955 0,11044635 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 0,000 0,06577955 0,11037049 ! blastoderm segmentation GO:0007350 19 10 0,000 0,06577955 0,11029474 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,06577955 0,11021909 ! response to dsRNA GO:0043331 23 10 0,000 0,06577955 0,11014355 ! DNA ligation GO:0006266 18 10 0,000 0,06577955 0,11006811 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,06577955 0,10999277 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,06577955 0,10991754 ! melanosome localization GO:0032400 16 10 0,000 0,06577955 0,1098424 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,06577955 0,10976737 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,06577955 0,10969245 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,06577955 0,10961762 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,06577955 0,1095429 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,06577955 0,10946828 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,06577955 0,10939376 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,06577955 0,10931934 ! protein sumoylation GO:0016925 17 10 0,000 0,06577955 0,10924503 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,06577955 0,10917081 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,06577955 0,1090967 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,06577955 0,10902268 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,06577955 0,10894877 ! salivary gland development GO:0007431 28 10 0,000 0,06577955 0,10887496 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,06577955 0,10880124 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,06577955 0,10872763 ! midbrain development GO:0030901 14 10 0,000 0,06577955 0,10865412 ! musculoskeletal movement GO:0050881 16 10 0,000 0,06577955 0,1085807 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,06577955 0,10850738 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,06577955 0,10843417 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,06577955 0,10836105 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,06577955 0,10828803 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,06577955 0,10821511 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,06577955 0,10814229 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,06577955 0,10806956 ! detection of calcium ion GO:0005513 24 10 0,000 0,06577955 0,10799693 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,06577955 0,1079244 ! blastocyst formation GO:0001825 18 10 0,000 0,06577955 0,10785197 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,06577955 0,10777964 ! cerebellar cortex development GO:0021695 16 10 0,000 0,06577955 0,1077074 ! positive regulation of amine transport GO:0051954 17 10 0,000 0,06577955 0,10763526 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,06577955 0,10756321 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,06577955 0,10749126 ! viral reproductive process GO:0022415 132 62 1,000 0,06641001 0,10844896 ! nucleoside metabolic process GO:0009116 91 62 1,000 0,06641001 0,10837652 ! regulation of mitosis GO:0007088 112 63 1,000 0,0682902 0,11137047 GO:0051783|regulation of nuclear division, ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 1,000 0,07210264 0,11750951 ! multicellular organism reproduction GO:0032504 123 65 1,000 0,07210264 0,11743117 GO:0048609|reproductive process in a multicellular organism, ! negative regulation of muscle development GO:0048635 27 11 0,000 0,07211565 0,11737411 ! respiratory burst GO:0045730 17 11 0,000 0,07211565 0,11729596 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,07211565 0,11721792 ! neuron fate specification GO:0048665 18 11 0,000 0,07211565 0,11713999 ! telencephalon cell migration GO:0022029 23 11 0,000 0,07211565 0,11706215 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,07211565 0,11698442 ! thyroid gland development GO:0030878 26 11 0,000 0,07211565 0,11690679 ! synapsis GO:0007129 14 11 0,000 0,07211565 0,11682927 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,07211565 0,11675185 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 0,000 0,07211565 0,11667453 ! response to pain GO:0048265 27 11 0,000 0,07211565 0,11659731 ! blood vessel remodeling GO:0001974 30 11 0,000 0,07211565 0,1165202 ! positive regulation of endothelial cell proliferation GO:0001938 23 11 0,000 0,07211565 0,11644319 ! bone resorption GO:0045453 16 11 0,000 0,07211565 0,11636627 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,07211565 0,11628946 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,07211565 0,11621276 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,07211565 0,11613615 ! melanocyte differentiation GO:0030318 20 11 0,000 0,07211565 0,11605964 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,07211565 0,11598324 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,07211565 0,11590693 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,07211565 0,11583073 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,07211565 0,11575463 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,07211565 0,11567862 ! UV protection GO:0009650 20 11 0,000 0,07211565 0,11560272 ! adult heart development GO:0007512 16 11 0,000 0,07211565 0,11552691 ! chondrocyte differentiation GO:0002062 27 11 0,000 0,07211565 0,11545121 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,07211565 0,1153756 ! macroautophagy GO:0016236 19 11 0,000 0,07211565 0,11530009 ! temperature homeostasis GO:0001659 18 11 0,000 0,07211565 0,11522468 ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,07211565 0,11514937 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,07211565 0,11507416 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,07211565 0,11499905 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 0,07211565 0,11492403 ! regulation of organ growth GO:0046620 14 11 0,000 0,07211565 0,11484911 ! pigment granule localization GO:0051875 20 11 0,000 0,07211565 0,11477429 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,07211565 0,11469957 ! vasoconstriction GO:0042310 20 11 0,000 0,07211565 0,11462494 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,07211565 0,11455042 ! embryonic axis specification GO:0000578 19 11 0,000 0,07211565 0,11447598 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,07211565 0,11440165 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,07211565 0,11432741 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,07211565 0,11425327 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,07211565 0,11417922 GO:0006809|nitric oxide biosynthetic process, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,07211565 0,11410527 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,07211565 0,11403142 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,07211565 0,11395766 ! prophase GO:0051324 17 11 0,000 0,07211565 0,11388399 ! nucleosome positioning GO:0016584 15 11 0,000 0,07211565 0,11381043 ! regulation of isotype switching GO:0045191 24 11 0,000 0,07211565 0,11373695 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,07211565 0,11366357 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,07211565 0,11359029 ! apical protein localization GO:0045176 18 11 0,000 0,07211565 0,1135171 ! acid secretion GO:0046717 20 11 0,000 0,07211565 0,113444 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,07211565 0,113371 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,07211565 0,1132981 ! positive regulation of leukocyte migration GO:0002687 28 11 0,000 0,07211565 0,11322528 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,07211565 0,11315256 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,07211565 0,11307994 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,07211565 0,1130074 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! cholesterol efflux GO:0033344 21 11 0,000 0,07211565 0,11293496 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,07211565 0,11286261 ! negative regulation of glucose import GO:0046325 18 11 0,000 0,07211565 0,11279036 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 26 11 0,000 0,07211565 0,1127182 ! embryonic gut development GO:0048566 19 11 0,000 0,07211565 0,11264612 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,07211565 0,11257415 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,07211565 0,11250226 ! activation of innate immune response GO:0002218 16 11 0,000 0,07211565 0,11243047 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,07211565 0,11235876 ! lysogeny GO:0030069 22 11 0,000 0,07211565 0,11228715 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,07211565 0,11221563 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,07211565 0,1121442 ! sequestering of metal ion GO:0051238 15 11 0,000 0,07211565 0,11207286 ! nucleus localization GO:0051647 22 11 0,000 0,07211565 0,11200161 ! embryonic limb morphogenesis GO:0030326 139 67 1,000 0,07598235 0,11793195 GO:0035113|embryonic appendage morphogenesis, ! chromosome segregation GO:0007059 127 67 1,000 0,07598235 0,11785707 ! secondary metabolic process GO:0019748 125 67 1,000 0,07598235 0,11778229 ! myeloid cell differentiation GO:0030099 126 67 1,000 0,07598235 0,1177076 ! extracellular matrix organization GO:0030198 146 68 1,000 0,07794666 0,12067407 ! negative regulation of ligase activity GO:0051352 116 68 1,000 0,07794666 0,12059765 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! detection of external stimulus GO:0009581 102 68 1,000 0,07794666 0,12052132 ! viral reproduction GO:0016032 142 68 1,000 0,07794666 0,12044509 ! regulation of lipase activity GO:0060191 137 68 1,000 0,07794666 0,12036895 ! adaptive immune response GO:0002250 126 68 1,000 0,07794666 0,12029292 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! cell projection assembly GO:0030031 138 68 1,000 0,07794666 0,12021697 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,07840896 0,12085369 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,07840896 0,12077749 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,07840896 0,12070138 ! regulation of positive chemotaxis GO:0050926 22 12 0,000 0,07840896 0,12062537 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,07840896 0,12054946 ! protein complex disassembly GO:0043241 28 12 0,000 0,07840896 0,12047364 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,07840896 0,12039792 ! regulation of cell projection assembly GO:0060491 33 12 0,000 0,07840896 0,12032229 ! hippocampus development GO:0021766 29 12 0,000 0,07840896 0,12024676 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 0,000 0,07840896 0,12017132 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,07840896 0,12009598 ! T cell proliferation GO:0042098 32 12 0,000 0,07840896 0,12002073 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,07840896 0,11994558 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,07840896 0,11987052 ! ventral spinal cord development GO:0021517 25 12 0,000 0,07840896 0,11979555 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,07840896 0,11972068 ! drug transport GO:0015893 16 12 0,000 0,07840896 0,1196459 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,07840896 0,11957122 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,07840896 0,11949663 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,07840896 0,11942213 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,07840896 0,11934772 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,07840896 0,11927341 ! lipid digestion GO:0044241 21 12 0,000 0,07840896 0,11919919 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,07840896 0,11912506 ! entry into host cell GO:0030260 34 12 0,000 0,07840896 0,11905102 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,07840896 0,11897708 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,07840896 0,11890322 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,07840896 0,11882946 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,07840896 0,11875579 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,07840896 0,11868221 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,07840896 0,11860873 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,07840896 0,11853533 ! snRNA metabolic process GO:0016073 30 12 0,000 0,07840896 0,11846202 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,07840896 0,11838881 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,07840896 0,11831568 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,07840896 0,11824265 ! fucose catabolic process GO:0019317 25 12 0,000 0,07840896 0,1181697 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,07840896 0,11809685 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,07840896 0,11802409 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 0,07840896 0,11795141 ! zymogen activation GO:0031638 18 12 0,000 0,07840896 0,11787883 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,07840896 0,11780633 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,07840896 0,11773392 ! regulation of leukocyte migration GO:0002685 29 12 0,000 0,07840896 0,1176616 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,07840896 0,11758937 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,07840896 0,11751723 ! defense response to fungus GO:0050832 15 12 0,000 0,07840896 0,11744518 ! embryonic placenta development GO:0001892 21 12 0,000 0,07840896 0,11737322 ! lamellipodium assembly GO:0030032 24 12 0,000 0,07840896 0,11730134 ! response to cold GO:0009409 17 12 0,000 0,07840896 0,11722955 ! establishment of cell polarity GO:0030010 21 12 0,000 0,07840896 0,11715785 ! regulation of synapse organization GO:0050807 18 12 0,000 0,07840896 0,11708624 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 1,000 0,07992685 0,11927996 ! developmental maturation GO:0021700 128 69 1,000 0,07992685 0,11920714 ! activation of immune response GO:0002253 120 70 1,000 0,08192262 0,12210919 ! protein maturation by peptide bond cleavage GO:0051605 118 70 1,000 0,08192262 0,12203473 ! cGMP metabolic process GO:0046068 18 13 0,000 0,08465976 0,12603522 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,08465976 0,12595846 ! regulation of chemokine production GO:0032642 18 13 0,000 0,08465976 0,1258818 ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,08465976 0,12580523 ! peroxisomal transport GO:0043574 28 13 0,000 0,08465976 0,12572875 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,08465976 0,12565237 ! cartilage condensation GO:0001502 22 13 0,000 0,08465976 0,12557608 ! organelle fusion GO:0048284 36 13 0,000 0,08465976 0,12549988 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,08465976 0,12542377 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,08465976 0,12534776 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,08465976 0,12527183 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,08465976 0,125196 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,08465976 0,12512026 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,08465976 0,12504462 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,08465976 0,12496906 ! methionine metabolic process GO:0006555 31 13 0,000 0,08465976 0,1248936 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,08465976 0,12481822 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,08465976 0,12474294 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,08465976 0,12466775 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,08465976 0,12459265 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! cytokine metabolic process GO:0042107 24 13 0,000 0,08465976 0,12451764 ! cellular carbohydrate catabolic process GO:0044275 17 13 0,000 0,08465976 0,12444272 ! exocrine system development GO:0035272 34 13 0,000 0,08465976 0,12436789 ! asymmetric protein localization GO:0008105 24 13 0,000 0,08465976 0,12429315 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,08465976 0,1242185 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 0,08465976 0,12414394 ! L-glutamate transport GO:0015813 30 13 0,000 0,08465976 0,12406946 GO:0015800|acidic amino acid transport, ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,08465976 0,12399508 ! protein homotetramerization GO:0051289 24 13 0,000 0,08465976 0,12392079 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,08465976 0,12384659 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,08465976 0,12377247 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,08465976 0,12369844 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,08465976 0,12362451 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,08465976 0,12355066 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,08465976 0,12347689 ! histone methylation GO:0016571 29 13 0,000 0,08465976 0,12340322 ! chromatin silencing GO:0006342 29 13 0,000 0,08465976 0,12332963 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,08465976 0,12325614 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 0,08465976 0,12318273 ! regulation of epidermis development GO:0045682 19 13 0,000 0,08465976 0,1231094 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,08465976 0,12303617 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,08465976 0,12296302 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,08465976 0,12288996 ! regulation of mRNA stability GO:0043488 32 13 0,000 0,08465976 0,12281698 ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,08465976 0,12274409 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,08465976 0,12267129 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,08465976 0,12259858 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,08465976 0,12252595 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,08465976 0,1224534 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,08465976 0,12238095 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,08465976 0,12230857 ! insulin secretion GO:0030073 24 13 0,000 0,08465976 0,12223629 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,08465976 0,12216409 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 0,08465976 0,12209197 ! acrosome reaction GO:0007340 19 13 0,000 0,08465976 0,12201994 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,08465976 0,12194799 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,08465976 0,12187613 ! appendage morphogenesis GO:0035107 150 72 1,000 0,08595972 0,12367468 GO:0035108|limb morphogenesis, ! carbohydrate transport GO:0008643 114 72 1,000 0,08595972 0,12360188 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 1,000 0,08595972 0,12352918 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 1,000 0,08595972 0,12345656 ! regulation of MAPKKK cascade GO:0043408 157 72 1,000 0,08595972 0,12338402 ! appendage development GO:0048736 151 73 1,000 0,08800046 0,12623906 GO:0060173|limb development, ! acute inflammatory response GO:0002526 118 74 1,000 0,0900556 0,1291114 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 1,000 0,0900556 0,12903567 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,09086834 0,13012389 GO:0046579|positive regulation of Ras protein signal transduction, ! water transport GO:0006833 21 14 0,000 0,09086834 0,13004766 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,09086834 0,12997152 ! non-recombinational repair GO:0000726 29 14 0,000 0,09086834 0,12989547 GO:0006303|double-strand break repair via nonhomologous end joining, ! retina development in camera-type eye GO:0060041 28 14 0,000 0,09086834 0,12981951 ! RNA polyadenylation GO:0043631 32 14 0,000 0,09086834 0,12974363 ! lipid localization GO:0010876 32 14 0,000 0,09086834 0,12966785 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 0,09086834 0,12959215 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 0,000 0,09086834 0,12951654 ! regulated secretory pathway GO:0045055 24 14 0,000 0,09086834 0,12944102 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,09086834 0,12936559 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,09086834 0,12929025 ! arginine metabolic process GO:0006525 21 14 0,000 0,09086834 0,12921499 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,09086834 0,12913982 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,09086834 0,12906474 ! regulation of heart rate GO:0002027 25 14 0,000 0,09086834 0,12898975 ! organic alcohol transport GO:0015850 29 14 0,000 0,09086834 0,12891484 ! embryo implantation GO:0007566 30 14 0,000 0,09086834 0,12884002 ! neutral amino acid transport GO:0015804 28 14 0,000 0,09086834 0,12876529 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,09086834 0,12869064 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,09086834 0,12861608 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,09086834 0,12854161 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,09086834 0,12846722 ! ribosome assembly GO:0042255 18 14 0,000 0,09086834 0,12839292 ! cerebellum development GO:0021549 23 14 0,000 0,09086834 0,1283187 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,09086834 0,12824457 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,09086834 0,12817053 ! NADP metabolic process GO:0006739 24 14 0,000 0,09086834 0,12809657 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,09086834 0,1280227 ! oxygen transport GO:0015671 22 14 0,000 0,09086834 0,12794891 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,09086834 0,1278752 ! male genitalia development GO:0030539 26 14 0,000 0,09086834 0,12780159 ! regulation of RNA stability GO:0043487 33 14 0,000 0,09086834 0,12772805 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,09086834 0,1276546 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 0,09086834 0,12758124 ! phosphoinositide-mediated signaling GO:0048015 141 75 1,000 0,09212485 0,12927111 ! rhythmic process GO:0048511 142 75 1,000 0,09212485 0,1291969 ! phosphoinositide metabolic process GO:0030384 146 77 1,000 0,09630457 0,1349811 ! positive regulation of ligase activity GO:0051351 130 77 1,000 0,09630457 0,13490371 ! lactation GO:0007595 30 15 0,000 0,09703498 0,13584897 ! reproductive cellular process GO:0048610 22 15 0,000 0,09703498 0,13577117 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,09703498 0,13569345 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,09703498 0,13561582 ! superoxide anion generation GO:0042554 22 15 0,000 0,09703498 0,13553828 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,09703498 0,13546083 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,09703498 0,13538347 ! copper ion transport GO:0006825 22 15 0,000 0,09703498 0,1353062 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,09703498 0,13522901 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,09703498 0,13515191 ! sulfate transport GO:0008272 27 15 0,000 0,09703498 0,1350749 ! response to cAMP GO:0051591 25 15 0,000 0,09703498 0,13499798 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,09703498 0,13492115 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,09703498 0,1348444 ! response to hexose stimulus GO:0009746 25 15 0,000 0,09703498 0,13476774 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,09703498 0,13469117 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,09703498 0,13461468 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 0,09703498 0,13453828 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 0,09703498 0,13446197 ! regulation of exocytosis GO:0017157 26 15 0,000 0,09703498 0,13438575 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,09703498 0,13430961 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,09703498 0,13423355 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,09703498 0,13415759 ! regulation of vasodilation GO:0042312 27 15 0,000 0,09703498 0,13408171 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,09703498 0,13400591 ! histone deacetylation GO:0016575 24 15 0,000 0,09703498 0,1339302 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,09703498 0,13385458 ! water homeostasis GO:0030104 28 15 0,000 0,09703498 0,13377904 ! cofactor transport GO:0051181 30 15 0,000 0,09703498 0,13370359 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,09703498 0,13362822 ! muscle maintenance GO:0046716 26 15 0,000 0,09703498 0,13355293 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,09703498 0,13347773 ! intestinal absorption GO:0050892 31 15 0,000 0,09703498 0,13340262 ! dopamine metabolic process GO:0042417 35 15 0,000 0,09703498 0,13332759 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,09703498 0,13325265 ! heme biosynthetic process GO:0006783 33 15 0,000 0,09703498 0,13317778 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,09703498 0,13310301 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,09703498 0,13302831 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,09703498 0,13295371 ! actin filament polymerization GO:0030041 27 15 0,000 0,09703498 0,13287918 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,09703498 0,13280474 ! blood coagulation GO:0007596 151 79 1,000 0,10053738 0,13752118 GO:0050817|coagulation, ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 1,000 0,10267302 0,14036384 ! activation of protein kinase activity GO:0032147 170 80 1,000 0,10267302 0,14028534 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,10315996 0,14087188 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,10315996 0,14079318 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,10315996 0,14071457 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,10315996 0,14063605 ! bone remodeling GO:0046849 28 16 0,000 0,10315996 0,14055761 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,10315996 0,14047926 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,10315996 0,140401 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,10315996 0,14032282 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,10315996 0,14024474 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,10315996 0,14016674 ! startle response GO:0001964 28 16 0,000 0,10315996 0,14008882 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,10315996 0,140011 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,10315996 0,13993326 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,10315996 0,1398556 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,10315996 0,13977803 ! protein polyubiquitination GO:0000209 41 16 0,000 0,10315996 0,13970055 ! glutamate metabolic process GO:0006536 25 16 0,000 0,10315996 0,13962315 ! pituitary gland development GO:0021983 30 16 0,000 0,10315996 0,13954584 ! response to osmotic stress GO:0006970 27 16 0,000 0,10315996 0,13946862 ! lysosomal transport GO:0007041 31 16 0,000 0,10315996 0,13939148 ! fructose metabolic process GO:0006000 25 16 0,000 0,10315996 0,13931442 ! L-amino acid transport GO:0015807 33 16 0,000 0,10315996 0,13923745 ! stem cell development GO:0048864 46 16 0,000 0,10315996 0,13916057 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,10315996 0,13908377 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,10315996 0,13900706 ! intermediate filament-based process GO:0045103 36 16 0,000 0,10315996 0,13893043 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,10315996 0,13885388 ! negative regulation of immune response GO:0050777 38 16 0,000 0,10315996 0,13877742 ! axon cargo transport GO:0008088 46 16 0,000 0,10315996 0,13870104 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,10315996 0,13862475 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,10315996 0,13854854 ! positive regulation of protein import into nucleus GO:0042307 34 16 0,000 0,10315996 0,13847241 ! DNA replication initiation GO:0006270 28 16 0,000 0,10315996 0,13839637 ! neuron recognition GO:0008038 40 16 0,000 0,10315996 0,13832041 ! mRNA splice site selection GO:0006376 44 16 0,000 0,10315996 0,13824454 ! tissue regeneration GO:0042246 27 16 0,000 0,10315996 0,13816875 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,10315996 0,13809304 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,10315996 0,13801741 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,10315996 0,13794187 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,10315996 0,13786641 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,10315996 0,13779103 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,10315996 0,13771573 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,10315996 0,13764052 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,10315996 0,13756539 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,10315996 0,13749034 ! peptide hormone processing GO:0016486 27 16 0,000 0,10315996 0,13741537 ! protein import into nucleus GO:0006606 174 82 1,000 0,1069814 0,14242809 ! regulation of adenylate cyclase activity GO:0045761 165 83 1,000 0,10915361 0,14524089 ! cellular lipid catabolic process GO:0044242 150 83 1,000 0,10915361 0,14516183 ! nuclear import GO:0051170 177 83 1,000 0,10915361 0,14508285 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,10924357 0,14512346 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,10924357 0,14504459 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,10924357 0,14496581 ! signal complex assembly GO:0007172 47 17 0,000 0,10924357 0,14488711 ! filopodium assembly GO:0046847 42 17 0,000 0,10924357 0,14480849 ! endothelial cell migration GO:0043542 31 17 0,000 0,10924357 0,14472996 ! gene silencing by RNA GO:0031047 38 17 0,000 0,10924357 0,14465152 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,10924357 0,14457316 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,10924357 0,14449488 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,10924357 0,14441669 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,10924357 0,14433859 ! myoblast differentiation GO:0045445 50 17 0,000 0,10924357 0,14426057 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,10924357 0,14418263 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 0,000 0,10924357 0,14410478 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,10924357 0,14402701 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,10924357 0,14394933 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,10924357 0,14387172 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,10924357 0,14379421 ! NAD metabolic process GO:0019674 33 17 0,000 0,10924357 0,14371677 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,10924357 0,14363942 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,10924357 0,14356216 ! genitalia development GO:0048806 32 17 0,000 0,10924357 0,14348497 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,10924357 0,14340787 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,10924357 0,14333085 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,10924357 0,14325392 ! neutrophil chemotaxis GO:0030593 29 17 0,000 0,10924357 0,14317706 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,10924357 0,14310029 ! steroid catabolic process GO:0006706 34 17 0,000 0,10924357 0,14302361 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,10924357 0,142947 ! gas transport GO:0015669 26 17 0,000 0,10924357 0,14287048 ! organic cation transport GO:0015695 32 17 0,000 0,10924357 0,14279403 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,10924357 0,14271767 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,10924357 0,14264139 ! digestion GO:0007586 130 84 1,000 0,1113375 0,14529782 ! hemostasis GO:0007599 165 85 1,000 0,1135328 0,14808363 ! regulation of cyclase activity GO:0031279 168 85 1,000 0,1135328 0,14800461 ! positive regulation of protein complex assembly GO:0031334 34 18 0,000 0,11528608 0,15021008 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,11528608 0,15013001 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,11528608 0,15005003 ! limbic system development GO:0021761 40 18 0,000 0,11528608 0,14997013 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,11528608 0,14989032 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,11528608 0,14981059 ! adult walking behavior GO:0007628 36 18 0,000 0,11528608 0,14973094 ! patterning of blood vessels GO:0001569 43 18 0,000 0,11528608 0,14965138 ! heart looping GO:0001947 34 18 0,000 0,11528608 0,14957191 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,11528608 0,14949252 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,11528608 0,14941321 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,11528608 0,14933399 ! glycine metabolic process GO:0006544 30 18 0,000 0,11528608 0,14925485 ! glutamine metabolic process GO:0006541 29 18 0,000 0,11528608 0,1491758 ! response to retinoic acid GO:0032526 31 18 0,000 0,11528608 0,14909683 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,11528608 0,14901794 ! DNA integration GO:0015074 32 18 0,000 0,11528608 0,14893913 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,11528608 0,14886041 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,11528608 0,14878178 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,11528608 0,14870322 ! neural crest cell migration GO:0001755 41 18 0,000 0,11528608 0,14862475 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,11528608 0,14854636 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,11528608 0,14846806 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,11528608 0,14838983 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,11528608 0,14831169 GO:0033014|tetrapyrrole biosynthetic process, ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,11528608 0,14823363 ! detection of bacterium GO:0016045 22 18 0,000 0,11528608 0,14815566 ! microspike assembly GO:0030035 46 18 0,000 0,11528608 0,14807776 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,11528608 0,14799995 ! regulation of cAMP biosynthetic process GO:0030817 173 86 1,000 0,11573927 0,14850369 ! regulation of lyase activity GO:0051339 169 86 1,000 0,11573927 0,14842574 ! amine biosynthetic process GO:0009309 146 88 1,000 0,12018468 0,15404574 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,12128777 0,1553781 ! negative regulation of defense response GO:0031348 27 19 0,000 0,12128777 0,15529666 ! G1 phase of mitotic cell cycle GO:0000080 39 19 0,000 0,12128777 0,15521531 ! neuron maturation GO:0042551 46 19 0,000 0,12128777 0,15513405 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,12128777 0,15505287 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 0,12128777 0,15497178 ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,12128777 0,15489077 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,12128777 0,15480984 ! inositol metabolic process GO:0006020 33 19 0,000 0,12128777 0,154729 ! memory GO:0007613 34 19 0,000 0,12128777 0,15464824 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,12128777 0,15456757 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,12128777 0,15448698 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,12128777 0,15440648 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,12128777 0,15432606 ! pigmentation during development GO:0048066 42 19 0,000 0,12128777 0,15424572 ! response to vitamin A GO:0033189 32 19 0,000 0,12128777 0,15416547 ! heme metabolic process GO:0042168 40 19 0,000 0,12128777 0,1540853 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,12128777 0,15400522 ! response to fungus GO:0009620 26 19 0,000 0,12128777 0,15392521 ! peptide cross-linking GO:0018149 39 19 0,000 0,12128777 0,15384529 ! protein export from nucleus GO:0006611 40 19 0,000 0,12128777 0,15376546 ! heart process GO:0003015 32 19 0,000 0,12128777 0,1536857 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,12128777 0,15360603 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,12128777 0,15352644 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,12128777 0,15344694 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,12128777 0,15336751 ! vitamin transport GO:0051180 31 19 0,000 0,12128777 0,15328817 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,12128777 0,15320891 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,12128777 0,15312973 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,12128777 0,15305064 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,12128777 0,15297162 ! cilium assembly GO:0042384 38 19 0,000 0,12128777 0,15289269 ! peptide hormone secretion GO:0030072 32 19 0,000 0,12128777 0,15281384 ! regulation of cAMP metabolic process GO:0030814 182 89 1,000 0,12242314 0,15416481 ! protein localization in nucleus GO:0034504 192 89 1,000 0,12242314 0,15408539 ! positive regulation of protein modification process GO:0031401 156 90 1,000 0,12467177 0,15683478 ! response to unfolded protein GO:0006986 139 90 1,000 0,12467177 0,15675406 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 1,000 0,12693035 0,15951175 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! protein secretion GO:0009306 45 20 0,000 0,12724892 0,15982988 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,12724892 0,15974774 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,12724892 0,1596657 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,12724892 0,15958373 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,12724892 0,15950185 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 0,000 0,12724892 0,15942006 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,12724892 0,15933834 ! response to vitamin GO:0033273 36 20 0,000 0,12724892 0,15925672 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,12724892 0,15917517 ! forelimb morphogenesis GO:0035136 35 20 0,000 0,12724892 0,15909371 ! bile acid metabolic process GO:0008206 34 20 0,000 0,12724892 0,15901233 ! retinoid metabolic process GO:0001523 34 20 0,000 0,12724892 0,15893104 GO:0016101|diterpenoid metabolic process, ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,12724892 0,15884983 ! cellular response to unfolded protein GO:0034620 35 20 0,000 0,12724892 0,1587687 GO:0030968|endoplasmic reticulum unfolded protein response, ! body fluid secretion GO:0007589 33 20 0,000 0,12724892 0,15868765 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,12724892 0,15860669 ! peptide secretion GO:0002790 38 20 0,000 0,12724892 0,15852581 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,12724892 0,15844501 ! regulation of fatty acid metabolic process GO:0019217 45 20 0,000 0,12724892 0,15836429 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,12724892 0,15828366 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,12724892 0,15820311 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,12724892 0,15812264 ! cell-cell junction organization GO:0045216 43 20 0,000 0,12724892 0,15804225 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 0,000 0,12724892 0,15796195 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,12724892 0,15788172 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,12724892 0,15780158 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,12724892 0,15772152 ! regulation of glucose import GO:0046324 30 20 0,000 0,12724892 0,15764154 GO:0010827|regulation of glucose transport, ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,12724892 0,15756164 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,12724892 0,15748182 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,12724892 0,15740208 ! regulation of cell morphogenesis GO:0022604 243 93 1,000 0,13147635 0,16254895 ! regulation of cell killing GO:0031341 46 21 0,000 0,13316979 0,16455933 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,13316979 0,16447614 ! hormone secretion GO:0046879 39 21 0,000 0,13316979 0,16439302 ! cAMP metabolic process GO:0046058 41 21 0,000 0,13316979 0,16431 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,13316979 0,16422706 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,13316979 0,1641442 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,13316979 0,16406142 ! smooth muscle contraction GO:0006939 48 21 0,000 0,13316979 0,16397873 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,13316979 0,16389612 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,13316979 0,16381359 ! plasma membrane fusion GO:0045026 33 21 0,000 0,13316979 0,16373115 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,13316979 0,16364879 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,13316979 0,16356651 GO:0006692|prostanoid metabolic process, ! regulation of vasoconstriction GO:0019229 40 21 0,000 0,13316979 0,16348432 ! sensory perception of pain GO:0019233 33 21 0,000 0,13316979 0,16340221 ! diencephalon development GO:0021536 36 21 0,000 0,13316979 0,16332018 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,13316979 0,16323823 ! positive regulation of inflammatory response GO:0050729 41 21 0,000 0,13316979 0,16315637 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,13316979 0,16307458 ! collagen catabolic process GO:0030574 29 21 0,000 0,13316979 0,16299288 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,13316979 0,16291127 GO:0043450|alkene biosynthetic process, ! sperm-egg recognition GO:0035036 23 21 0,000 0,13316979 0,16282973 ! actin filament-based movement GO:0030048 47 21 0,000 0,13316979 0,16274827 ! female pregnancy GO:0007565 166 94 1,000 0,13376333 0,1633919 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 1,000 0,13605931 0,16611339 ! cofactor biosynthetic process GO:0051188 161 95 1,000 0,13605931 0,16603041 ! negative regulation of multicellular organismal process GO:0051241 174 95 1,000 0,13605931 0,16594752 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,13905066 0,16951136 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,13905066 0,16942681 ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,13905066 0,16934235 ! microtubule-based transport GO:0010970 59 22 0,000 0,13905066 0,16925798 ! hindlimb morphogenesis GO:0035137 47 22 0,000 0,13905066 0,16917368 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,13905066 0,16908948 ! inactivation of MAPK activity GO:0000188 45 22 0,000 0,13905066 0,16900535 ! vacuolar transport GO:0007034 41 22 0,000 0,13905066 0,16892131 ! central nervous system neuron development GO:0021954 47 22 0,000 0,13905066 0,16883735 ! fucose metabolic process GO:0006004 44 22 0,000 0,13905066 0,16875348 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,13905066 0,16866969 ! stem cell differentiation GO:0048863 57 22 0,000 0,13905066 0,16858598 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,13905066 0,16850236 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 0,13905066 0,16841882 ! cytolysis GO:0019835 27 22 0,000 0,13905066 0,16833536 ! vasodilation GO:0042311 40 22 0,000 0,13905066 0,16825198 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,13905066 0,16816869 ! positive regulation of locomotion GO:0040017 44 22 0,000 0,13905066 0,16808548 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! G1 phase GO:0051318 44 22 0,000 0,13905066 0,16800235 ! detection of chemical stimulus GO:0009593 42 22 0,000 0,13905066 0,16791931 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,13905066 0,16783634 ! positive regulation of intracellular transport GO:0032388 42 22 0,000 0,13905066 0,16775346 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,13905066 0,16767066 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,13905066 0,16758794 ! sarcomere organization GO:0045214 32 22 0,000 0,13905066 0,1675053 ! positive regulation of B cell activation GO:0050871 42 22 0,000 0,13905066 0,16742275 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,13905066 0,16734027 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,13905066 0,16725788 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,13905066 0,16717557 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,13905066 0,16709334 ! biogenic amine metabolic process GO:0006576 162 97 1,000 0,14067738 0,16896502 ! regulation of nucleotide metabolic process GO:0006140 197 98 1,000 0,14299904 0,17166912 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,14489179 0,17385592 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,14489179 0,17377057 ! gluconeogenesis GO:0006094 38 23 0,000 0,14489179 0,1736853 ! glycerol metabolic process GO:0006071 40 23 0,000 0,14489179 0,17360012 ! viral genome replication GO:0019079 44 23 0,000 0,14489179 0,17351502 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,14489179 0,17343001 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,14489179 0,17334508 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of chemotaxis GO:0050920 45 23 0,000 0,14489179 0,17326023 ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,14489179 0,17317546 ! axis specification GO:0009798 43 23 0,000 0,14489179 0,17309078 ! regulation of DNA recombination GO:0000018 51 23 0,000 0,14489179 0,17300618 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,14489179 0,17292167 ! peroxisome organization GO:0007031 43 23 0,000 0,14489179 0,17283723 ! lysosome organization GO:0007040 47 23 0,000 0,14489179 0,17275288 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,14489179 0,17266861 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,14489179 0,17258442 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,14489179 0,17250032 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,14489179 0,17241629 ! fatty acid transport GO:0015908 47 23 0,000 0,14489179 0,17233235 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,14489179 0,17224849 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,14489179 0,17216471 ! hormone transport GO:0009914 41 23 0,000 0,14489179 0,17208102 ! cell-cell recognition GO:0009988 28 23 0,000 0,14489179 0,1719974 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,14489179 0,17191387 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,14489179 0,17183041 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,14489179 0,17174704 ! positive regulation of immune response GO:0050778 175 100 1,000 0,14766649 0,17495114 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,15069346 0,17845086 GO:0016444|somatic cell DNA recombination, ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,15069346 0,1783644 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,15069346 0,17827803 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,15069346 0,17819174 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,15069346 0,17810553 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 0,15069346 0,1780194 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,15069346 0,17793336 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,15069346 0,1778474 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,15069346 0,17776153 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,15069346 0,17767574 GO:0042278|purine nucleoside metabolic process, ! positive regulation of cytoskeleton organization GO:0051495 52 24 0,000 0,15069346 0,17759003 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,15069346 0,1775044 GO:0051693|actin filament capping, ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,15069346 0,17741886 GO:0002708|positive regulation of lymphocyte mediated immunity, ! leukotriene metabolic process GO:0006691 47 24 0,000 0,15069346 0,17733339 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,15069346 0,17724801 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,15069346 0,17716272 ! membrane depolarization GO:0051899 45 24 0,000 0,15069346 0,1770775 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,15069346 0,17699237 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,15069346 0,17690732 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,15069346 0,17682235 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,15069346 0,17673746 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,15069346 0,17665265 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,15069346 0,17656793 GO:0033013|tetrapyrrole metabolic process, ! regulation of amine transport GO:0051952 41 24 0,000 0,15069346 0,17648328 ! positive regulation of fibroblast proliferation GO:0048146 48 25 0,000 0,15645593 0,18314415 ! myeloid leukocyte differentiation GO:0002573 46 25 0,000 0,15645593 0,18305644 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 0,000 0,15645593 0,18296881 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,15645593 0,18288126 ! leukocyte adhesion GO:0007159 55 25 0,000 0,15645593 0,1827938 ! phototransduction GO:0007602 37 25 0,000 0,15645593 0,18270642 ! keratinization GO:0031424 37 25 0,000 0,15645593 0,18261913 ! vacuole organization GO:0007033 49 25 0,000 0,15645593 0,18253192 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,15645593 0,18244479 ! receptor metabolic process GO:0043112 53 25 0,000 0,15645593 0,18235775 ! chromosome condensation GO:0030261 48 25 0,000 0,15645593 0,18227079 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,15645593 0,18218391 ! regulation of behavior GO:0050795 48 25 0,000 0,15645593 0,18209711 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,15645593 0,1820104 ! immunoglobulin production GO:0002377 62 25 0,000 0,15645593 0,18192377 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,15645593 0,18183722 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,15645593 0,18175075 ! initiation of viral infection GO:0019059 60 26 0,000 0,16217946 0,18831009 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,16217946 0,18822063 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,16217946 0,18813126 ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,16217946 0,18804197 ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,16217946 0,18795276 ! digestive system process GO:0022600 49 26 0,000 0,16217946 0,18786364 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,16217946 0,18777461 ! regulation of cellular ketone metabolic process GO:0010565 51 26 0,000 0,16217946 0,18768566 ! neural crest cell development GO:0014032 59 26 0,000 0,16217946 0,18759679 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,16217946 0,18750801 ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,16217946 0,18741931 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,16217946 0,1873307 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,16217946 0,18724217 ! regulation of blood coagulation GO:0030193 46 26 0,000 0,16217946 0,18715372 ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,16217946 0,18706536 ! telomere organization GO:0032200 46 26 0,000 0,16217946 0,18697708 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,16217946 0,18688888 ! neural tube closure GO:0001843 58 26 0,000 0,16217946 0,18680077 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 44 26 0,000 0,16217946 0,18671274 ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,16217946 0,18662479 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,16217946 0,18653692 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,16786432 0,19298472 ! embryonic pattern specification GO:0009880 49 27 0,000 0,16786432 0,19289395 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,16786432 0,19280326 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,16786432 0,19271266 ! positive regulation of cell projection organization GO:0031346 66 27 0,000 0,16786432 0,19262214 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,16786432 0,1925317 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,16786432 0,19244136 ! iron ion transport GO:0006826 65 27 0,000 0,16786432 0,19235109 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,16786432 0,19226091 ! superoxide metabolic process GO:0006801 41 27 0,000 0,16786432 0,19217082 ! tube lumen formation GO:0035148 59 27 0,000 0,16786432 0,19208081 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,16786432 0,19199088 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,16786432 0,19190104 ! neuron fate commitment GO:0048663 52 28 0,000 0,17351076 0,19826323 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,17351076 0,19817054 ! vesicle docking GO:0048278 55 28 0,000 0,17351076 0,19807794 ! circadian rhythm GO:0007623 56 28 0,000 0,17351076 0,19798542 ! negative regulation of protein modification process GO:0031400 66 28 0,000 0,17351076 0,19789299 ! fat cell differentiation GO:0045444 57 28 0,000 0,17351076 0,19780065 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,17351076 0,19770839 ! sperm motility GO:0030317 37 28 0,000 0,17351076 0,19761622 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,17351076 0,19752413 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,17351076 0,19743213 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,17351076 0,19734022 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,17351076 0,19724839 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,17351076 0,19715665 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,17351076 0,19706499 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,17351076 0,19697342 ! glutathione metabolic process GO:0006749 42 28 0,000 0,17351076 0,19688193 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,17351076 0,19679052 ! lipid oxidation GO:0034440 48 28 0,000 0,17351076 0,19669921 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,17351076 0,19660797 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,17351076 0,19651682 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 0,000 0,17911905 0,20277471 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,17911905 0,20268079 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,17911905 0,20258696 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! autophagy GO:0006914 47 29 0,000 0,17911905 0,20249321 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,17911905 0,20239955 ! primary neural tube formation GO:0014020 61 29 0,000 0,17911905 0,20230598 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,17911905 0,20221249 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,17911905 0,20211909 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,17911905 0,20202578 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,17911905 0,20193255 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,18468944 0,20811637 ! phenol metabolic process GO:0018958 56 30 0,000 0,18468944 0,20802042 ! negative regulation of protein complex assembly GO:0031333 68 30 0,000 0,18468944 0,20792456 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,18468944 0,20782878 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,18468944 0,2077331 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,18468944 0,2076375 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,18468944 0,20754199 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,18468944 0,20744657 ! acute-phase response GO:0006953 50 30 0,000 0,18468944 0,20735124 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,18468944 0,20725599 ! myofibril assembly GO:0030239 50 30 0,000 0,18468944 0,20716083 GO:0055002|striated muscle cell development, ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,18468944 0,20706576 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,18468944 0,20697078 ! cell fate determination GO:0001709 64 30 0,000 0,18468944 0,20687588 ! phospholipid transport GO:0015914 65 30 0,000 0,18468944 0,20678107 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,18468944 0,20668634 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,18468944 0,20659171 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,18468944 0,20649716 ! regulation of coagulation GO:0050818 52 30 0,000 0,18468944 0,20640269 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,19022218 0,2124887 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,19022218 0,21239158 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,19022218 0,21229456 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,19022218 0,21219762 ! regulation of innate immune response GO:0045088 57 31 0,000 0,19022218 0,21210077 ! peptide transport GO:0015833 60 31 0,000 0,19022218 0,21200401 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,19022218 0,21190733 ! detection of light stimulus GO:0009583 44 31 0,000 0,19022218 0,21181075 ! natural killer cell activation GO:0030101 50 31 0,000 0,19022218 0,21171425 ! cofactor catabolic process GO:0051187 54 31 0,000 0,19022218 0,21161784 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,19022218 0,21152152 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,19022218 0,21142529 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,19571753 0,21743426 ! collagen metabolic process GO:0032963 49 32 0,000 0,19571753 0,21733542 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,19571753 0,21723668 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,19571753 0,21713802 ! muscle cell development GO:0055001 52 32 0,000 0,19571753 0,21703946 ! mesoderm formation GO:0001707 73 32 0,000 0,19571753 0,21694098 ! hexose biosynthetic process GO:0019319 53 32 0,000 0,19571753 0,2168426 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,19571753 0,2167443 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,19571753 0,21664609 ! gene silencing GO:0016458 71 32 0,000 0,19571753 0,21654797 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,20117574 0,22248635 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,20117574 0,22238568 GO:0055092|sterol homeostasis, ! pigment biosynthetic process GO:0046148 73 33 0,000 0,20117574 0,22228509 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,20117574 0,2221846 ! leukocyte chemotaxis GO:0030595 55 33 0,000 0,20117574 0,2220842 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,20117574 0,22198389 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,20117574 0,22188368 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,20659707 0,22776022 ! cholesterol transport GO:0030301 62 34 0,000 0,20659707 0,22765748 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,20659707 0,22755484 ! spliceosome assembly GO:0000245 75 34 0,000 0,20659707 0,22745229 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,20659707 0,22734984 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,20659707 0,22724747 ! formation of primary germ layer GO:0001704 76 34 0,000 0,20659707 0,2271452 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,20659707 0,22704302 ! adult locomotory behavior GO:0008344 62 34 0,000 0,20659707 0,22694093 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,21198175 0,2327512 ! negative regulation of secretion GO:0051048 68 35 0,000 0,21198175 0,23264664 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,21198175 0,23254217 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,21198175 0,2324378 ! membrane docking GO:0022406 69 35 0,000 0,21198175 0,23233352 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,21198175 0,23222934 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,21198175 0,23212524 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,21198175 0,23202125 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,21198175 0,23191734 ! ceramide metabolic process GO:0006672 72 35 0,000 0,21198175 0,23181353 ! sterol transport GO:0015918 63 35 0,000 0,21198175 0,23170981 ! placenta development GO:0001890 53 35 0,000 0,21198175 0,23160618 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,21733004 0,23734345 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,21733004 0,2372374 ! protein targeting to membrane GO:0006612 75 36 0,000 0,21733004 0,23713144 ! regulation of proteolysis GO:0030162 77 36 0,000 0,21733004 0,23702558 ! aerobic respiration GO:0009060 56 36 0,000 0,21733004 0,23691981 ! cytokine production GO:0001816 68 36 0,000 0,21733004 0,23681413 ! embryonic organ development GO:0048568 67 36 0,000 0,21733004 0,23670856 ! monosaccharide biosynthetic process GO:0046364 57 36 0,000 0,21733004 0,23660307 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 0,000 0,22264218 0,24227833 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,22264218 0,24217046 ! actomyosin structure organization GO:0031032 68 37 0,000 0,22264218 0,24206268 ! tissue remodeling GO:0048771 78 37 0,000 0,22264218 0,241955 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,22264218 0,24184742 ! organic anion transport GO:0015711 82 38 0,000 0,22791841 0,24746875 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,22791841 0,24735881 ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,22791841 0,24724897 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,22791841 0,24713923 ! glycogen metabolic process GO:0005977 63 38 0,000 0,22791841 0,24702959 ! neural tube formation GO:0001841 79 38 0,000 0,22791841 0,24692004 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,23315898 0,25248555 ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,23315898 0,25237368 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,23315898 0,25226191 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,23315898 0,25215024 ! positive regulation of leukocyte proliferation GO:0070665 70 39 0,000 0,23315898 0,25203867 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! glucan metabolic process GO:0044042 64 39 0,000 0,23315898 0,2519272 GO:0006073|cellular glucan metabolic process, ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,23836413 0,25743748 ! lipid homeostasis GO:0055088 75 40 0,000 0,23836413 0,25732372 ! mismatch repair GO:0006298 58 40 0,000 0,23836413 0,25721006 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,23836413 0,2570965 ! RNA export from nucleus GO:0006405 61 41 0,000 0,24353409 0,26255683 ! mRNA catabolic process GO:0006402 79 41 0,000 0,24353409 0,26244101 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,24353409 0,2623253 ! regulation of hormone secretion GO:0046883 69 41 0,000 0,24353409 0,26220969 ! establishment or maintenance of cell polarity GO:0007163 96 41 0,000 0,24353409 0,26209418 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,24353409 0,26197877 ! feeding behavior GO:0007631 69 41 0,000 0,24353409 0,26186346 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,24353409 0,26174825 GO:0015986|ATP synthesis coupled proton transport, ! embryonic epithelial tube formation GO:0001838 85 41 0,000 0,24353409 0,26163315 ! RNA modification GO:0009451 64 41 0,000 0,24353409 0,26151814 ! alcohol biosynthetic process GO:0046165 65 42 0,000 0,2486691 0,26691503 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,2486691 0,26679781 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,2486691 0,26668069 ! regulation of protein secretion GO:0050708 77 42 0,000 0,2486691 0,26656367 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,2486691 0,26644676 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,2537694 0,27179248 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,2537694 0,27167337 ! regulation of tube size GO:0035150 76 43 0,000 0,2537694 0,27155437 GO:0050880|regulation of blood vessel size, ! striated muscle cell differentiation GO:0051146 91 43 0,000 0,2537694 0,27143548 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,2537694 0,27131669 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,2537694 0,271198 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,2537694 0,27107942 ! ion transmembrane transport GO:0034220 79 43 0,000 0,2537694 0,27096094 ! neuron migration GO:0001764 85 43 0,000 0,2537694 0,27084257 ! regulation of myeloid cell differentiation GO:0045637 105 43 0,000 0,2537694 0,2707243 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,25883521 0,27600804 ! energy reserve metabolic process GO:0006112 76 44 0,000 0,25883521 0,27588762 ! positive regulation of response to external stimulus GO:0032103 88 44 0,000 0,25883521 0,2757673 ! striated muscle contraction GO:0006941 85 44 0,000 0,25883521 0,27564709 ! phagocytosis GO:0006909 105 44 0,000 0,25883521 0,27552698 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,25883521 0,27540698 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,26386678 0,28063846 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,26386678 0,28051634 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,26386678 0,28039432 ! polyol metabolic process GO:0019751 77 45 0,000 0,26386678 0,28027241 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,26886434 0,28545657 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,26886434 0,28533257 ! glycolysis GO:0006096 71 46 0,000 0,26886434 0,28520867 ! leukocyte migration GO:0050900 75 46 0,000 0,26886434 0,28508488 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,26886434 0,2849612 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,26886434 0,28483763 ! positive regulation of protein transport GO:0051222 80 46 0,000 0,26886434 0,28471416 ! neural tube development GO:0021915 91 47 0,000 0,2738281 0,28984491 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,2738281 0,28971938 ! positive regulation of defense response GO:0031349 88 48 0,000 0,2787583 0,29480802 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 0,000 0,2787583 0,29468046 ! endosome transport GO:0016197 127 48 0,000 0,2787583 0,294553 ! vascular process in circulatory system GO:0003018 85 48 0,000 0,2787583 0,29442565 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,2787583 0,29429842 ! regulation of inflammatory response GO:0050727 84 48 0,000 0,2787583 0,29417129 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,2787583 0,29404427 ! response to calcium ion GO:0051592 94 49 0,000 0,28365517 0,29908053 ! JNK cascade GO:0007254 106 49 0,000 0,28365517 0,2989515 ! regulation of ion transport GO:0043269 86 50 0,000 0,28851893 0,30394642 ! induction of apoptosis by extracellular signals GO:0008624 99 50 0,000 0,28851893 0,30381541 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,28851893 0,30368451 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,28851893 0,30355372 ! viral infectious cycle GO:0019058 104 51 0,000 0,2933498 0,30850347 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,2933498 0,30837072 ! peptide metabolic process GO:0006518 80 51 0,000 0,2933498 0,30823809 ! Notch signaling pathway GO:0007219 111 52 0,000 0,29814801 0,31314513 ! morphogenesis of embryonic epithelium GO:0016331 106 52 0,000 0,29814801 0,31301056 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,29814801 0,31287611 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,29814801 0,31274177 ! excretion GO:0007588 87 52 0,000 0,29814801 0,31260754 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,29814801 0,31247344 ! amino acid activation GO:0043038 98 52 0,000 0,29814801 0,31233944 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,30291377 0,31719603 ! inner ear development GO:0048839 89 53 0,000 0,30291377 0,31706012 ! chromatin remodeling GO:0006338 122 53 0,000 0,30291377 0,31692434 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,30291377 0,31678867 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,3076473 0,32160135 ! neuromuscular process GO:0050905 107 54 0,000 0,3076473 0,32146379 ! regulation of muscle contraction GO:0006937 94 54 0,000 0,3076473 0,32132636 ! membrane fusion GO:0006944 122 54 0,000 0,3076473 0,32118904 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,3076473 0,32105184 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,3076473 0,32091475 ! regulation of cell shape GO:0008360 142 54 0,000 0,3076473 0,32077778 ! RNA catabolic process GO:0006401 103 55 0,000 0,31234882 0,32554103 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,31234882 0,3254022 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,31234882 0,3252635 ! cell recognition GO:0008037 98 55 0,000 0,31234882 0,32512491 ! regulation of protein polymerization GO:0032271 117 55 0,000 0,31234882 0,32498644 ! glucose catabolic process GO:0006007 88 56 0,000 0,31701855 0,32970469 ! chloride transport GO:0006821 102 57 0,000 0,32165669 0,33438608 ! regulation of actin filament length GO:0030832 118 58 0,000 0,32626347 0,33903091 ! cellular polysaccharide metabolic process GO:0044264 93 58 0,000 0,32626347 0,33888676 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,32626347 0,33874274 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,32626347 0,33859884 ! gastrulation GO:0007369 122 58 0,000 0,32626347 0,33845506 ! nuclear export GO:0051168 110 59 0,000 0,33083909 0,34305599 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,33538377 0,34762093 ! regulation of endocytosis GO:0030100 104 60 0,000 0,33538377 0,34747351 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,33538377 0,34732622 ! adult behavior GO:0030534 104 60 0,000 0,33538377 0,34717904 ! positive regulation of secretion GO:0051047 110 61 0,000 0,3398977 0,35170271 ! regulation of cellular component size GO:0032535 125 61 0,000 0,3398977 0,35155381 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,3398977 0,35140503 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,3398977 0,35125638 ! cytokine-mediated signaling pathway GO:0019221 112 61 0,000 0,3398977 0,35110786 ! regulation of heart contraction GO:0008016 123 61 0,000 0,3398977 0,35095946 ! proton transport GO:0015992 117 61 0,000 0,3398977 0,35081119 ! negative regulation of response to stimulus GO:0048585 106 61 0,000 0,3398977 0,35066304 ! tRNA processing GO:0008033 102 62 0,000 0,34438111 0,35513847 ! regulation of protein complex assembly GO:0043254 132 63 0,000 0,34883419 0,35957887 ! mesoderm development GO:0007498 128 63 0,000 0,34883419 0,35942721 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,34883419 0,35927568 ! hydrogen transport GO:0006818 121 64 0,000 0,35325714 0,36367771 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,35325714 0,36352452 ! integrin-mediated signaling pathway GO:0007229 160 64 0,000 0,35325714 0,36337145 ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,35765018 0,36773544 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,35765018 0,36758073 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,36201351 0,37190874 ! regulation of lipid metabolic process GO:0019216 132 66 0,000 0,36201351 0,37175241 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,36634731 0,37604474 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,36634731 0,3758868 ! regulation of cellular response to stress GO:0080135 142 68 0,000 0,3706518 0,38014372 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,3706518 0,3799842 ! hexose catabolic process GO:0019320 113 68 0,000 0,3706518 0,37982481 ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,3706518 0,37966555 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 0,000 0,3706518 0,37950643 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,37492717 0,38372311 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,37492717 0,38356242 ! single fertilization GO:0007338 83 69 0,000 0,37492717 0,38340187 ! cell redox homeostasis GO:0045454 114 70 0,000 0,37917361 0,38758206 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,38339132 0,3917294 ! cAMP-mediated signaling GO:0019933 124 71 0,000 0,38339132 0,39156563 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,3875805 0,39567871 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,3875805 0,39551343 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,39174133 0,39959252 ! regulation of immune effector process GO:0002697 156 73 0,000 0,39174133 0,39942574 ! amino acid transport GO:0006865 148 74 0,000 0,39587401 0,4034711 ! transition metal ion transport GO:0000041 143 75 0,000 0,39997873 0,40748459 ! regulation of actin cytoskeleton organization GO:0032956 167 76 0,000 0,40405568 0,41146645 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,40405568 0,41129501 ! regulation of blood pressure GO:0008217 134 76 0,000 0,40405568 0,41112371 ! amine catabolic process GO:0009310 136 77 0,000 0,40810503 0,41507102 ! neurotransmitter transport GO:0006836 142 77 0,000 0,40810503 0,41489829 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,40810503 0,41472571 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,40810503 0,41455326 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,40810503 0,41438096 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,41212699 0,41829091 ! antigen processing and presentation GO:0019882 117 78 0,000 0,41212699 0,41811721 ! fertilization GO:0009566 99 78 0,000 0,41212699 0,41794364 ! positive regulation of lymphocyte activation GO:0051251 142 78 0,000 0,41212699 0,41777022 ! regulation of actin filament-based process GO:0032970 170 79 0,000 0,41612173 0,4216447 ! steroid biosynthetic process GO:0006694 146 79 0,000 0,41612173 0,42146989 ! regulation of synaptic transmission GO:0050804 159 79 0,000 0,41612173 0,42129522 ! muscle cell differentiation GO:0042692 178 81 0,000 0,42403029 0,42912427 ! exocytosis GO:0006887 153 83 0,000 0,43183216 0,43683891 ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,43183216 0,4366581 ! inorganic anion transport GO:0015698 156 83 0,000 0,43183216 0,43647744 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,43952879 0,44407313 ! regulation of transmission of nerve impulse GO:0051969 167 85 0,000 0,43952879 0,44388956 ! positive regulation of cell activation GO:0050867 161 86 0,000 0,44333808 0,44755162 GO:0002696|positive regulation of leukocyte activation, ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,44712158 0,45118465 ! alcohol catabolic process GO:0046164 142 87 0,000 0,44712158 0,45099836 ! nucleosome assembly GO:0006334 126 87 0,000 0,44712158 0,45081223 ! cellular respiration GO:0045333 143 88 0,000 0,45087948 0,4544136 ! sensory perception of smell GO:0007608 117 88 0,000 0,45087948 0,45422621 ! chromatin assembly GO:0031497 128 88 0,000 0,45087948 0,45403898 ! cellular defense response GO:0006968 123 89 0,000 0,45461194 0,45760897 ! regulation of neurological system process GO:0031644 175 89 0,000 0,45461194 0,4574205 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,45831913 0,46096074 ! defense response to bacterium GO:0042742 112 91 0,000 0,46200123 0,46447284 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,4656584 0,467957 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 0,000 0,46929081 0,47141343 GO:0010498|proteasomal protein catabolic process, ! amine transport GO:0015837 181 93 0,000 0,46929081 0,47121967 ! vitamin metabolic process GO:0006766 153 93 0,000 0,46929081 0,47102607 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,47289864 0,47445231 ! sterol metabolic process GO:0016125 166 94 0,000 0,47289864 0,47425754 ! carbohydrate biosynthetic process GO:0016051 158 94 0,000 0,47289864 0,47406293 ! regulation of defense response GO:0031347 171 95 0,000 0,47648203 0,47745923 ! nucleosome organization GO:0034728 143 95 0,000 0,47648203 0,47726347 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,47648203 0,47706787 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,47648203 0,47687243 ! mRNA transport GO:0051028 185 100 0,000 0,49403837 0,49424067 ! hormone metabolic process GO:0042445 171 100 0,000 0,49403837 0,49403837