pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6700-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of mitochondrial membrane permeability GO:0046902 14 5 3,000 8,834E-09 2,125E-05 ! negative regulation of phosphorylation GO:0042326 47 24 5,000 8,855E-09 1,065E-05 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 5,000 1,498E-08 1,202E-05 GO:0045936|negative regulation of phosphate metabolic process, ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 4,000 2,172E-08 1,306E-05 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 3,000 6,12E-08 2,945E-05 ! gland development GO:0048732 206 88 7,000 1,194E-07 4,789E-05 ! induction of positive chemotaxis GO:0050930 15 9 3,000 2,181E-07 7,496E-05 ! negative regulation of protein kinase activity GO:0006469 130 67 6,000 2,873E-07 8,642E-05 ! negative regulation of kinase activity GO:0033673 131 68 6,000 3,186E-07 8,516E-05 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 3,000 3,616E-07 8,7E-05 ! negative regulation of transferase activity GO:0051348 140 72 6,000 4,735E-07 1,036E-04 ! induction of apoptosis by intracellular signals GO:0008629 93 45 5,000 4,78E-07 9,585E-05 ! negative regulation of glucose import GO:0046325 17 11 3,000 5,653E-07 1,046E-04 GO:0010829|negative regulation of glucose transport, ! regulation of positive chemotaxis GO:0050926 19 12 3,000 8,436E-07 1,45E-04 GO:0050927|positive regulation of positive chemotaxis, ! negative regulation of protein modification process GO:0031400 60 28 4,000 9,897E-07 1,588E-04 ! release of cytochrome c from mitochondria GO:0001836 30 14 3,000 1,689E-06 2,539E-04 ! negative regulation of bone remodeling GO:0046851 33 15 3,000 2,291E-06 3,242E-04 ! positive regulation of MAP kinase activity GO:0043406 160 93 6,000 2,712E-06 3,625E-04 ! regulation of membrane potential GO:0042391 164 93 6,000 2,712E-06 3,435E-04 ! L-serine biosynthetic process GO:0006564 6 5 2,000 2,73E-06 3,284E-04 ! negative regulation of tissue remodeling GO:0034104 36 16 3,000 3,039E-06 3,482E-04 ! defense response to virus GO:0051607 37 16 3,000 3,039E-06 3,323E-04 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 5,000 5,198E-06 5,437E-04 ! nuclear migration GO:0007097 12 6 2,000 5,434E-06 5,447E-04 ! positive regulation of pseudopodium assembly GO:0031274 14 6 2,000 5,434E-06 5,229E-04 GO:0031272|regulation of pseudopodium assembly, ! apoptotic mitochondrial changes GO:0008637 41 20 3,000 7,925E-06 7,334E-04 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 3,000 7,925E-06 7,062E-04 ! regulation of glucose import GO:0046324 29 20 3,000 7,925E-06 6,81E-04 GO:0010827|regulation of glucose transport, ! regulation of lipid kinase activity GO:0043550 13 7 2,000 9,463E-06 7,851E-04 ! macrophage differentiation GO:0030225 11 7 2,000 9,463E-06 7,589E-04 ! regulation of protein homodimerization activity GO:0043496 18 7 2,000 9,463E-06 7,344E-04 ! inactivation of MAPK activity GO:0000188 39 21 3,000 9,74E-06 7,323E-04 ! positive regulation of locomotion GO:0040017 39 21 3,000 9,74E-06 7,101E-04 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! regulation of chemotaxis GO:0050920 40 22 3,000 1,184E-05 8,381E-04 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 4,000 1,255E-05 8,625E-04 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 2,000 1,507E-05 1,007E-03 ! establishment of nucleus localization GO:0040023 16 8 2,000 1,507E-05 9,798E-04 ! response to hypoxia GO:0001666 171 81 5,000 1,567E-05 9,921E-04 ! regulation of behavior GO:0050795 43 24 3,000 1,703E-05 1,051E-03 ! response to oxygen levels GO:0070482 176 83 5,000 1,803E-05 1,084E-03 ! vasculogenesis GO:0001570 46 25 3,000 2,017E-05 1,184E-03 ! T cell selection GO:0045058 23 9 2,000 2,249E-05 1,288E-03 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 2,000 2,249E-05 1,259E-03 ! regulation of mitochondrial membrane potential GO:0051881 17 9 2,000 2,249E-05 1,23E-03 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 3,000 2,371E-05 1,268E-03 ! mitochondrial membrane organization GO:0007006 57 27 3,000 2,77E-05 1,449E-03 ! negative regulation of neuron differentiation GO:0045665 42 27 3,000 2,77E-05 1,418E-03 ! ossification GO:0001503 188 90 5,000 2,863E-05 1,435E-03 ! bone development GO:0060348 189 91 5,000 3,049E-05 1,497E-03 ! regulation of smooth muscle cell migration GO:0014910 27 10 2,000 3,198E-05 1,539E-03 ! L-serine metabolic process GO:0006563 18 10 2,000 3,198E-05 1,509E-03 ! positive regulation of B cell proliferation GO:0030890 16 10 2,000 3,198E-05 1,48E-03 ! peptidyl-tyrosine modification GO:0018212 50 28 3,000 3,215E-05 1,459E-03 ! positive regulation of cell migration GO:0030335 126 57 4,000 3,616E-05 1,611E-03 ! interphase of mitotic cell cycle GO:0051329 209 95 5,000 3,89E-05 1,702E-03 ! chondrocyte differentiation GO:0002062 24 11 2,000 4,376E-05 1,88E-03 ! negative regulation of ossification GO:0030279 26 11 2,000 4,376E-05 1,847E-03 ! thymus development GO:0048538 27 11 2,000 4,376E-05 1,815E-03 ! nucleus localization GO:0051647 19 11 2,000 4,376E-05 1,784E-03 ! interphase GO:0051325 213 98 5,000 4,635E-05 1,859E-03 ! protein amino acid autophosphorylation GO:0046777 141 60 4,000 4,642E-05 1,831E-03 ! negative regulation of response to stimulus GO:0048585 100 60 4,000 4,642E-05 1,801E-03 ! response to peptide hormone stimulus GO:0043434 122 61 4,000 5,03E-05 1,921E-03 ! negative regulation of MAP kinase activity GO:0043407 69 32 3,000 5,532E-05 2,08E-03 ! regulation of B cell proliferation GO:0030888 20 12 2,000 5,806E-05 2,149E-03 ! regulation of cell projection assembly GO:0060491 30 12 2,000 5,806E-05 2,117E-03 ! gland morphogenesis GO:0022612 29 12 2,000 5,806E-05 2,085E-03 ! positive regulation of cell motion GO:0051272 146 64 4,000 6,345E-05 2,245E-03 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 3,000 7,062E-05 2,462E-03 ! lipid localization GO:0010876 28 13 2,000 7,511E-05 2,582E-03 GO:0019915|lipid storage, ! organelle fusion GO:0048284 32 13 2,000 7,511E-05 2,545E-03 ! serine family amino acid biosynthetic process GO:0009070 17 13 2,000 7,511E-05 2,51E-03 ! T cell differentiation in the thymus GO:0033077 31 14 2,000 9,514E-05 3,136E-03 ! response to gamma radiation GO:0010332 28 14 2,000 9,514E-05 3,093E-03 ! tissue remodeling GO:0048771 76 37 3,000 9,904E-05 3,177E-03 ! cellular response to insulin stimulus GO:0032869 82 37 3,000 9,904E-05 3,135E-03 ! regulation of the force of heart contraction GO:0002026 26 15 2,000 1,184E-04 3,698E-03 ! mammary gland development GO:0030879 86 39 3,000 1,221E-04 3,766E-03 ! filopodium assembly GO:0046847 32 16 2,000 1,45E-04 4,415E-03 ! axon cargo transport GO:0008088 43 16 2,000 1,45E-04 4,36E-03 ! regulation of T cell differentiation GO:0045580 70 41 3,000 1,488E-04 4,419E-03 ! regulation of peptidase activity GO:0052547 134 79 4,000 1,733E-04 5,084E-03 ! positive regulation of phosphorylation GO:0042327 129 79 4,000 1,733E-04 5,022E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 2,000 1,752E-04 5,018E-03 ! regulation of protein binding GO:0043393 33 17 2,000 1,752E-04 4,959E-03 ! neutrophil chemotaxis GO:0030593 27 17 2,000 1,752E-04 4,901E-03 ! negative regulation of homeostatic process GO:0032845 33 17 2,000 1,752E-04 4,845E-03 ! microspike assembly GO:0030035 36 17 2,000 1,752E-04 4,79E-03 ! positive regulation of response to external stimulus GO:0032103 77 43 3,000 1,795E-04 4,852E-03 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 4,000 1,949E-04 5,21E-03 GO:0045937|positive regulation of phosphate metabolic process, ! regulation of neuron differentiation GO:0045664 167 81 4,000 1,949E-04 5,153E-03 ! response to retinoic acid GO:0032526 26 18 2,000 2,092E-04 5,471E-03 ! peptidyl-serine phosphorylation GO:0018105 38 18 2,000 2,092E-04 5,412E-03 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 2,000 2,092E-04 5,355E-03 ! negative regulation of cell migration GO:0030336 115 46 3,000 2,337E-04 5,919E-03 ! response to insulin stimulus GO:0032868 95 46 3,000 2,337E-04 5,857E-03 ! response to vitamin A GO:0033189 27 19 2,000 2,472E-04 6,132E-03 ! JNK cascade GO:0007254 91 47 3,000 2,542E-04 6,24E-03 ! mitochondrion organization GO:0007005 148 86 4,000 2,58E-04 6,271E-03 ! mitochondrial transport GO:0006839 82 48 3,000 2,758E-04 6,637E-03 ! regulation of lymphocyte differentiation GO:0045619 81 48 3,000 2,758E-04 6,571E-03 ! regulation of mast cell proliferation GO:0070666 81 48 3,000 2,758E-04 6,507E-03 ! response to vitamin GO:0033273 31 20 2,000 2,895E-04 6,762E-03 ! regulation of carbohydrate metabolic process GO:0006109 38 20 2,000 2,895E-04 6,697E-03 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 2,000 2,895E-04 6,633E-03 ! peptidyl-serine modification GO:0018209 43 20 2,000 2,895E-04 6,57E-03 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 3,000 2,988E-04 6,72E-03 ! response to temperature stimulus GO:0009266 76 49 3,000 2,988E-04 6,658E-03 ! cell structure disassembly during apoptosis GO:0006921 30 21 2,000 3,361E-04 7,419E-03 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 2,000 3,361E-04 7,351E-03 ! positive regulation of inflammatory response GO:0050729 35 21 2,000 3,361E-04 7,285E-03 ! regulation of leukocyte proliferation GO:0070663 88 51 3,000 3,489E-04 7,495E-03 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! negative regulation of multicellular organismal process GO:0051241 166 93 4,000 3,711E-04 7,902E-03 ! regulation of angiogenesis GO:0045765 114 52 3,000 3,761E-04 7,937E-03 ! regulation of muscle contraction GO:0006937 81 52 3,000 3,761E-04 7,868E-03 ! membrane fusion GO:0006944 110 52 3,000 3,761E-04 7,8E-03 ! microtubule-based transport GO:0010970 54 22 2,000 3,873E-04 7,964E-03 ! glutamate signaling pathway GO:0007215 41 22 2,000 3,873E-04 7,897E-03 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 2,000 3,873E-04 7,83E-03 ! positive regulation of B cell activation GO:0050871 38 22 2,000 3,873E-04 7,765E-03 ! response to UV GO:0009411 104 53 3,000 4,047E-04 8,047E-03 ! neuron fate determination GO:0048664 7 5 1,000 4,202E-04 8,287E-03 ! negative regulation of bone resorption GO:0045779 10 5 1,000 4,202E-04 8,22E-03 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 1,000 4,202E-04 8,154E-03 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 1,000 4,202E-04 8,088E-03 ! positive regulation of glycolysis GO:0045821 14 5 1,000 4,202E-04 8,024E-03 ! parathyroid gland development GO:0060017 13 5 1,000 4,202E-04 7,961E-03 ! epithelial cell proliferation GO:0050673 9 5 1,000 4,202E-04 7,899E-03 ! negative regulation of survival gene product expression GO:0008634 8 5 1,000 4,202E-04 7,838E-03 ! microvillus organization GO:0032528 7 5 1,000 4,202E-04 7,777E-03 GO:0030033|microvillus assembly, ! regulation of glycogen metabolic process GO:0070873 11 5 1,000 4,202E-04 7,718E-03 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 4,202E-04 7,66E-03 ! peptidyl-threonine phosphorylation GO:0018107 20 5 1,000 4,202E-04 7,602E-03 ! positive regulation of vasoconstriction GO:0045907 9 5 1,000 4,202E-04 7,545E-03 ! homeostasis of number of cells within a tissue GO:0048873 12 5 1,000 4,202E-04 7,489E-03 ! negative regulation of T cell mediated immunity GO:0002710 12 5 1,000 4,202E-04 7,434E-03 GO:0002707|negative regulation of lymphocyte mediated immunity, ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 1,000 4,202E-04 7,38E-03 ! B cell homeostasis GO:0001782 13 5 1,000 4,202E-04 7,326E-03 ! coenzyme A biosynthetic process GO:0015937 7 5 1,000 4,202E-04 7,274E-03 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 1,000 4,202E-04 7,222E-03 ! regulation of mitochondrial depolarization GO:0051900 13 5 1,000 4,202E-04 7,171E-03 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 1,000 4,202E-04 7,12E-03 ! regulation of sensory perception GO:0051931 7 5 1,000 4,202E-04 7,07E-03 GO:0051930|regulation of sensory perception of pain, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 1,000 4,202E-04 7,021E-03 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 1,000 4,202E-04 6,973E-03 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! phospholipid scrambling GO:0017121 8 5 1,000 4,202E-04 6,925E-03 ! cellular anion homeostasis GO:0030002 9 5 1,000 4,202E-04 6,878E-03 GO:0055081|anion homeostasis, ! leukocyte differentiation GO:0002521 202 96 4,000 4,296E-04 6,984E-03 ! myeloid leukocyte differentiation GO:0002573 40 23 2,000 4,432E-04 7,157E-03 ! response to ethanol GO:0045471 46 23 2,000 4,432E-04 7,11E-03 ! sex determination GO:0007530 47 23 2,000 4,432E-04 7,062E-03 ! negative regulation of cell motion GO:0051271 134 55 3,000 4,666E-04 7,385E-03 ! response to virus GO:0009615 160 98 4,000 4,723E-04 7,428E-03 ! regulation of alpha-beta T cell activation GO:0046634 42 24 2,000 5,041E-04 7,876E-03 ! lymphocyte proliferation GO:0046651 48 24 2,000 5,041E-04 7,825E-03 ! membrane depolarization GO:0051899 39 24 2,000 5,041E-04 7,775E-03 ! regulation of oxidoreductase activity GO:0051341 46 24 2,000 5,041E-04 7,726E-03 ! regulation of bone remodeling GO:0046850 137 57 3,000 5,349E-04 8,145E-03 ! osteoblast differentiation GO:0001649 60 25 2,000 5,701E-04 8,627E-03 ! interaction with host GO:0051701 62 25 2,000 5,701E-04 8,573E-03 ! regulation of tissue remodeling GO:0034103 140 58 3,000 5,716E-04 8,542E-03 ! sleep GO:0030431 13 6 1,000 6,276E-04 9,321E-03 ! thymic T cell selection GO:0045061 12 6 1,000 6,276E-04 9,264E-03 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 1,000 6,276E-04 9,208E-03 ! positive regulation of neuroblast proliferation GO:0002052 13 6 1,000 6,276E-04 9,152E-03 ! neuron apoptosis GO:0051402 9 6 1,000 6,276E-04 9,097E-03 ! male sex determination GO:0030238 15 6 1,000 6,276E-04 9,042E-03 ! negative regulation of gliogenesis GO:0014014 18 6 1,000 6,276E-04 8,988E-03 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 14 6 1,000 6,276E-04 8,935E-03 ! regulation of myeloid cell apoptosis GO:0033032 13 6 1,000 6,276E-04 8,883E-03 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 1,000 6,276E-04 8,831E-03 GO:0045625|regulation of T-helper 1 cell differentiation, ! positive regulation of microtubule polymerization GO:0031116 13 6 1,000 6,276E-04 8,779E-03 ! insulin receptor signaling pathway GO:0008286 64 26 2,000 6,414E-04 8,92E-03 ! regulation of endothelial cell proliferation GO:0001936 57 26 2,000 6,414E-04 8,869E-03 ! leukocyte proliferation GO:0070661 52 26 2,000 6,414E-04 8,818E-03 GO:0032943|mononuclear cell proliferation, ! regulation of protein complex assembly GO:0043254 117 61 3,000 6,924E-04 9,466E-03 ! positive regulation of cell projection organization GO:0031346 58 27 2,000 7,181E-04 9,761E-03 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 2,000 7,181E-04 9,706E-03 ! response to toxin GO:0009636 47 27 2,000 7,181E-04 9,652E-03 ! ear development GO:0043583 103 62 3,000 7,364E-04 9,844E-03 ! regulation of homeostatic process GO:0032844 134 62 3,000 7,364E-04 9,789E-03 ! regulation of lipid metabolic process GO:0019216 115 63 3,000 7,824E-04 0,01034291 ! positive regulation of T cell differentiation GO:0045582 42 28 2,000 8,004E-04 0,01052343 ! prostate gland development GO:0030850 13 7 1,000 8,749E-04 0,01144 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 8,749E-04 0,01137816 ! N-terminal protein amino acid acetylation GO:0006474 13 7 1,000 8,749E-04 0,01131699 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 1,000 8,749E-04 0,01125647 ! mRNA stabilization GO:0048255 18 7 1,000 8,749E-04 0,0111966 GO:0043489|RNA stabilization, ! sensory perception of temperature stimulus GO:0050951 11 7 1,000 8,749E-04 0,01113736 ! positive regulation of isotype switching GO:0045830 15 7 1,000 8,749E-04 0,01107874 GO:0045911|positive regulation of DNA recombination, ! vesicle fusion GO:0006906 17 7 1,000 8,749E-04 0,01102073 ! organ growth GO:0035265 15 7 1,000 8,749E-04 0,01096333 ! B cell lineage commitment GO:0002326 21 7 1,000 8,749E-04 0,01090653 ! T cell lineage commitment GO:0002360 16 7 1,000 8,749E-04 0,01085031 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 1,000 8,749E-04 0,01079467 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of respiratory burst GO:0060263 11 7 1,000 8,749E-04 0,01073959 ! coenzyme A metabolic process GO:0015936 12 7 1,000 8,749E-04 0,01068508 ! peptidyl-threonine modification GO:0018210 25 7 1,000 8,749E-04 0,01063111 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 1,000 8,749E-04 0,01057769 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 1,000 8,749E-04 0,0105248 ! regulation of microtubule polymerization GO:0031113 15 7 1,000 8,749E-04 0,01047244 ! negative regulation of protein complex assembly GO:0031333 59 29 2,000 8,885E-04 0,01058264 ! cell projection assembly GO:0030031 120 66 3,000 9,323E-04 0,01105003 ! regulation of B cell activation GO:0050864 50 30 2,000 9,825E-04 0,0115874 ! negative regulation of cell growth GO:0030308 132 67 3,000 9,865E-04 0,01157803 ! activation of MAPK activity GO:0000187 115 67 3,000 9,865E-04 0,01152182 ! lung development GO:0030324 144 67 3,000 9,865E-04 0,01146616 ! serine family amino acid metabolic process GO:0009069 49 31 2,000 1,083E-03 0,0125219 ! negative regulation of cell size GO:0045792 134 69 3,000 1,101E-03 0,01267936 ! urogenital system development GO:0001655 137 69 3,000 1,101E-03 0,01261898 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 1,161E-03 0,01324422 ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 1,000 1,161E-03 0,01318174 ! T-helper 1 type immune response GO:0042088 12 8 1,000 1,161E-03 0,01311986 ! pigment granule organization GO:0048753 16 8 1,000 1,161E-03 0,01305855 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 1,161E-03 0,01299781 ! ER overload response GO:0006983 12 8 1,000 1,161E-03 0,01293764 ! regulation of pigmentation during development GO:0048070 24 8 1,000 1,161E-03 0,01287802 ! melanin metabolic process GO:0006582 15 8 1,000 1,161E-03 0,01281894 ! positive regulation of endothelial cell migration GO:0010595 19 8 1,000 1,161E-03 0,01276041 ! cerebral cortex neuron differentiation GO:0021895 16 8 1,000 1,161E-03 0,01270241 ! regulation of vascular permeability GO:0043114 12 8 1,000 1,161E-03 0,01264493 ! response to UV-B GO:0010224 16 8 1,000 1,161E-03 0,01258797 ! regulation of fat cell differentiation GO:0045598 15 8 1,000 1,161E-03 0,01253152 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 1,000 1,161E-03 0,01247558 ! mitochondrion morphogenesis GO:0070584 14 8 1,000 1,161E-03 0,01242013 ! regulation of T-helper 1 type immune response GO:0002825 9 8 1,000 1,161E-03 0,01236517 ! B cell receptor signaling pathway GO:0050853 16 8 1,000 1,161E-03 0,0123107 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 1,000 1,161E-03 0,01225671 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 1,000 1,161E-03 0,01220319 ! respiratory tube development GO:0030323 150 70 3,000 1,162E-03 0,01215811 ! response to ionizing radiation GO:0010212 65 32 2,000 1,189E-03 0,01238192 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 2,000 1,189E-03 0,01232855 ! reproductive structure development GO:0048608 113 71 3,000 1,225E-03 0,01265371 ! regulation of MAPKKK cascade GO:0043408 142 71 3,000 1,225E-03 0,01259963 ! regulation of caspase activity GO:0043281 122 72 3,000 1,291E-03 0,0132168 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 3,000 1,291E-03 0,0131608 ! respiratory system development GO:0060541 153 72 3,000 1,291E-03 0,01310527 ! leukocyte chemotaxis GO:0030595 50 33 2,000 1,301E-03 0,01315621 GO:0060326|cell chemotaxis, ! regulation of striated muscle tissue development GO:0016202 69 34 2,000 1,421E-03 0,01430022 ! regulation of endopeptidase activity GO:0052548 125 74 3,000 1,429E-03 0,014328 ! regulation of developmental growth GO:0048638 15 9 1,000 1,487E-03 0,01484442 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 1,487E-03 0,01478308 ! regulation of epithelial cell differentiation GO:0030856 14 9 1,000 1,487E-03 0,01472224 ! regulation of glycolysis GO:0006110 21 9 1,000 1,487E-03 0,0146619 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 1,000 1,487E-03 0,01460206 ! behavioral fear response GO:0001662 22 9 1,000 1,487E-03 0,0145427 GO:0002209|behavioral defense response, ! regulation of Notch signaling pathway GO:0008593 22 9 1,000 1,487E-03 0,01448382 ! motor axon guidance GO:0008045 16 9 1,000 1,487E-03 0,01442542 ! protein heterooligomerization GO:0051291 16 9 1,000 1,487E-03 0,01436749 ! alpha-beta T cell differentiation GO:0046632 21 9 1,000 1,487E-03 0,01431002 ! response to amine stimulus GO:0014075 13 9 1,000 1,487E-03 0,01425301 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! gas homeostasis GO:0033483 16 9 1,000 1,487E-03 0,01419645 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 1,000 1,487E-03 0,01414033 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 1,000 1,487E-03 0,01408466 GO:0000084|S phase of mitotic cell cycle, ! cell-matrix adhesion GO:0007160 163 75 3,000 1,502E-03 0,01417287 ! regulation of muscle development GO:0048634 70 35 2,000 1,546E-03 0,01453233 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 2,000 1,546E-03 0,01447578 ! regulation of synaptic plasticity GO:0048167 64 35 2,000 1,546E-03 0,01441967 ! positive regulation of lymphocyte activation GO:0051251 127 77 3,000 1,656E-03 0,0153796 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 2,000 1,679E-03 0,01553486 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of cell development GO:0010720 80 36 2,000 1,679E-03 0,01547534 ! establishment or maintenance of cell polarity GO:0007163 83 37 2,000 1,818E-03 0,01669629 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 1,000 1,851E-03 0,01693022 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 1,000 1,851E-03 0,01686609 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 1,000 1,851E-03 0,01680244 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 1,000 1,851E-03 0,01673927 ! lung alveolus development GO:0048286 26 10 1,000 1,851E-03 0,01667658 ! pathogenesis GO:0009405 13 10 1,000 1,851E-03 0,01661435 ! negative regulation of striated muscle development GO:0045843 19 10 1,000 1,851E-03 0,01655259 ! B cell proliferation GO:0042100 18 10 1,000 1,851E-03 0,01649128 ! regulation of bone resorption GO:0045124 25 10 1,000 1,851E-03 0,01643043 ! regulation of gliogenesis GO:0014013 23 10 1,000 1,851E-03 0,01637002 GO:0045685|regulation of glial cell differentiation, ! alpha-beta T cell activation GO:0046631 23 10 1,000 1,851E-03 0,01631006 ! response to dsRNA GO:0043331 20 10 1,000 1,851E-03 0,01625054 ! DNA ligation GO:0006266 19 10 1,000 1,851E-03 0,01619144 ! regulation of B cell differentiation GO:0045577 19 10 1,000 1,851E-03 0,01613278 ! negative regulation of MAPKKK cascade GO:0043409 20 10 1,000 1,851E-03 0,01607454 ! positive regulation of leukocyte migration GO:0002687 25 10 1,000 1,851E-03 0,01601671 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 1,000 1,851E-03 0,01595931 GO:0043470|regulation of carbohydrate catabolic process, ! oocyte development GO:0048599 17 10 1,000 1,851E-03 0,01590231 ! response to nicotine GO:0035094 20 10 1,000 1,851E-03 0,01584572 ! negative regulation of immune effector process GO:0002698 20 10 1,000 1,851E-03 0,01578953 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 1,000 1,851E-03 0,01573373 ! localization within membrane GO:0051668 20 10 1,000 1,851E-03 0,01567833 ! positive regulation of DNA metabolic process GO:0051054 72 38 2,000 1,965E-03 0,0165848 ! positive regulation of leukocyte proliferation GO:0070665 62 38 2,000 1,965E-03 0,01652681 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! T cell activation GO:0042110 168 81 3,000 1,995E-03 0,01672106 ! cell-substrate adhesion GO:0031589 171 81 3,000 1,995E-03 0,016663 ! response to nutrient GO:0007584 125 82 3,000 2,086E-03 0,01736875 ! cellular response to hormone stimulus GO:0032870 167 82 3,000 2,086E-03 0,01730886 ! learning GO:0007612 77 39 2,000 2,118E-03 0,0175123 ! negative regulation of muscle development GO:0048635 20 11 1,000 2,252E-03 0,01855729 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 1,000 2,252E-03 0,01849396 ! T cell proliferation GO:0042098 26 11 1,000 2,252E-03 0,01843105 ! blood vessel remodeling GO:0001974 29 11 1,000 2,252E-03 0,01836857 ! positive regulation of endothelial cell proliferation GO:0001938 22 11 1,000 2,252E-03 0,01830652 ! peptide or protein amino-terminal blocking GO:0018409 21 11 1,000 2,252E-03 0,01824488 ! indolalkylamine metabolic process GO:0006586 17 11 1,000 2,252E-03 0,01818365 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! positive regulation of T cell mediated immunity GO:0002711 24 11 1,000 2,252E-03 0,01812284 ! neuroblast proliferation GO:0007405 24 11 1,000 2,252E-03 0,01806243 ! regulation of isotype switching GO:0045191 22 11 1,000 2,252E-03 0,01800242 ! regulation of leukocyte migration GO:0002685 26 11 1,000 2,252E-03 0,01794281 ! oocyte differentiation GO:0009994 18 11 1,000 2,252E-03 0,01788359 ! T cell receptor signaling pathway GO:0050852 23 11 1,000 2,252E-03 0,01782477 ! regulation of embryonic development GO:0045995 27 11 1,000 2,252E-03 0,01776632 ! negative regulation of transport GO:0051051 153 84 3,000 2,278E-03 0,01791388 ! negative regulation of growth GO:0045926 155 84 3,000 2,278E-03 0,01785553 ! positive regulation of cell activation GO:0050867 145 85 3,000 2,379E-03 0,0185822 GO:0002696|positive regulation of leukocyte activation, ! regulation of T cell proliferation GO:0042129 71 41 2,000 2,447E-03 0,01905356 ! T cell differentiation GO:0030217 81 41 2,000 2,447E-03 0,01899209 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 2,000 2,623E-03 0,02028989 ! positive regulation of cellular catabolic process GO:0031331 31 12 1,000 2,691E-03 0,02075172 ! virus-host interaction GO:0019048 29 12 1,000 2,691E-03 0,02068542 ! hippocampus development GO:0021766 26 12 1,000 2,691E-03 0,02061954 ! focal adhesion formation GO:0048041 35 12 1,000 2,691E-03 0,02055408 ! entry into host cell GO:0030260 32 12 1,000 2,691E-03 0,02048904 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 1,000 2,691E-03 0,0204244 ! histone acetylation GO:0016573 26 12 1,000 2,691E-03 0,02036018 ! peptidyl-lysine modification GO:0018205 21 12 1,000 2,691E-03 0,02029635 ! T cell homeostasis GO:0043029 25 12 1,000 2,691E-03 0,02023292 ! spleen development GO:0048536 22 12 1,000 2,691E-03 0,02016989 ! digestive tract morphogenesis GO:0048546 26 12 1,000 2,691E-03 0,02010725 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! negative regulation of mast cell proliferation GO:0070667 23 12 1,000 2,691E-03 0,020045 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 1,000 2,691E-03 0,01998314 ! response to cold GO:0009409 17 12 1,000 2,691E-03 0,01992165 ! positive regulation of protein modification process GO:0031401 136 88 3,000 2,698E-03 0,01991457 ! regulation of epithelial cell proliferation GO:0050678 111 43 2,000 2,806E-03 0,02064536 ! sex differentiation GO:0007548 145 90 3,000 2,927E-03 0,02147039 ! male sex differentiation GO:0046661 76 44 2,000 2,997E-03 0,02191621 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 2,000 2,997E-03 0,0218498 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 1,000 3,167E-03 0,02301772 ! regulation of skeletal muscle fiber development GO:0048742 32 13 1,000 3,167E-03 0,02294839 ! plasma membrane organization GO:0007009 24 13 1,000 3,167E-03 0,02287947 ! Golgi organization GO:0007030 24 13 1,000 3,167E-03 0,02281097 ! cellular carbohydrate catabolic process GO:0044275 15 13 1,000 3,167E-03 0,02274288 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 1,000 3,167E-03 0,02267519 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 1,000 3,167E-03 0,02260791 ! nucleoside triphosphate catabolic process GO:0009143 21 13 1,000 3,167E-03 0,02254102 ! regulation of monooxygenase activity GO:0032768 33 13 1,000 3,167E-03 0,02247453 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 1,000 3,167E-03 0,02240843 ! regulation of mRNA stability GO:0043488 31 13 1,000 3,167E-03 0,02234271 ! positive regulation of protein polymerization GO:0032273 25 13 1,000 3,167E-03 0,02227738 ! leukocyte migration GO:0050900 68 45 2,000 3,196E-03 0,02241575 ! pigmentation GO:0043473 100 46 2,000 3,402E-03 0,02379589 ! regulation of T cell activation GO:0050863 158 94 3,000 3,423E-03 0,02387405 ! forebrain development GO:0030900 188 95 3,000 3,556E-03 0,02472629 ! regulation of Rho protein signal transduction GO:0035023 213 95 3,000 3,556E-03 0,02465503 ! positive regulation of defense response GO:0031349 76 47 2,000 3,617E-03 0,02500637 ! regulation of adaptive immune response GO:0002819 84 47 2,000 3,617E-03 0,02493472 ! rRNA transcription GO:0009303 25 14 1,000 3,679E-03 0,02528721 ! N-terminal protein amino acid modification GO:0031365 27 14 1,000 3,679E-03 0,02521517 ! regulation of S phase GO:0033261 23 14 1,000 3,679E-03 0,02514354 ! hair follicle morphogenesis GO:0031069 26 14 1,000 3,679E-03 0,02507231 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 1,000 3,679E-03 0,02500148 GO:0060675|ureteric bud morphogenesis, ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 1,000 3,679E-03 0,02493106 ! regulation of RNA stability GO:0043487 32 14 1,000 3,679E-03 0,02486102 ! positive regulation of cell cycle GO:0045787 89 48 2,000 3,84E-03 0,02587708 ! cellular component disassembly GO:0022411 86 48 2,000 3,84E-03 0,0258048 ! activation of caspase activity GO:0006919 84 48 2,000 3,84E-03 0,02573292 ! regulation of inflammatory response GO:0050727 75 48 2,000 3,84E-03 0,02566144 ! induction of apoptosis by extracellular signals GO:0008624 89 49 2,000 4,071E-03 0,0271294 ! endocrine system development GO:0035270 104 49 2,000 4,071E-03 0,02705445 ! skeletal muscle tissue development GO:0007519 186 99 3,000 4,121E-03 0,0273115 GO:0060538|skeletal muscle organ development, ! regulation of skeletal muscle tissue development GO:0048641 35 15 1,000 4,226E-03 0,02793499 ! heterophilic cell adhesion GO:0007157 39 15 1,000 4,226E-03 0,02785845 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 1,000 4,226E-03 0,02778234 ! pituitary gland development GO:0021983 29 15 1,000 4,226E-03 0,02770664 ! regulation of vasodilation GO:0042312 26 15 1,000 4,226E-03 0,02763135 ! regulation of T cell mediated immunity GO:0002709 33 15 1,000 4,226E-03 0,02755646 ! positive regulation of oxidoreductase activity GO:0051353 22 15 1,000 4,226E-03 0,02748199 ! regulation of T-helper cell differentiation GO:0045622 26 15 1,000 4,226E-03 0,02740791 ! dopamine metabolic process GO:0042417 35 15 1,000 4,226E-03 0,02733423 ! lymphocyte homeostasis GO:0002260 30 15 1,000 4,226E-03 0,02726095 ! regulation of cell projection organization GO:0031344 121 50 2,000 4,31E-03 0,02772516 ! regulation of ossification GO:0030278 117 50 2,000 4,31E-03 0,02765123 ! inner ear development GO:0048839 79 50 2,000 4,31E-03 0,02757769 ! negative regulation of immune system process GO:0002683 95 50 2,000 4,31E-03 0,02750454 ! cellular amino acid biosynthetic process GO:0008652 75 51 2,000 4,557E-03 0,02900746 ! vesicle organization GO:0016050 107 51 2,000 4,557E-03 0,02893093 ! epithelial tube morphogenesis GO:0060562 98 51 2,000 4,557E-03 0,02885479 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 4,809E-03 0,03037042 ! embryonic forelimb morphogenesis GO:0035115 28 16 1,000 4,809E-03 0,03029091 ! bone remodeling GO:0046849 27 16 1,000 4,809E-03 0,03021182 ! startle response GO:0001964 28 16 1,000 4,809E-03 0,03013315 ! auditory receptor cell differentiation GO:0042491 32 16 1,000 4,809E-03 0,03005488 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 1,000 4,809E-03 0,02997702 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 1,000 4,809E-03 0,02989956 ! negative regulation of immune response GO:0050777 35 16 1,000 4,809E-03 0,0298225 ! neuron recognition GO:0008038 35 16 1,000 4,809E-03 0,02974583 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 1,000 4,809E-03 0,02966956 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 1,000 4,809E-03 0,02959368 ! negative regulation of leukocyte proliferation GO:0070664 31 16 1,000 4,809E-03 0,02951819 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of growth GO:0045927 90 52 2,000 4,813E-03 0,02946754 ! cartilage development GO:0051216 90 52 2,000 4,813E-03 0,02939275 ! synapse organization GO:0050808 85 52 2,000 4,813E-03 0,02931833 ! activation of phospholipase C activity GO:0007202 103 54 2,000 5,351E-03 0,03251081 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of cell killing GO:0031343 32 17 1,000 5,427E-03 0,03289105 ! positive regulation of protein complex assembly GO:0031334 32 17 1,000 5,427E-03 0,03280841 ! metencephalon development GO:0022037 30 17 1,000 5,427E-03 0,03272619 ! limbic system development GO:0021761 36 17 1,000 5,427E-03 0,03264437 ! regulation of viral genome replication GO:0045069 28 17 1,000 5,427E-03 0,03256296 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 1,000 5,427E-03 0,03248196 ! regulation of survival gene product expression GO:0045884 33 17 1,000 5,427E-03 0,03240136 ! negative regulation of protein catabolic process GO:0042177 40 17 1,000 5,427E-03 0,03232116 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 1,000 5,427E-03 0,03224135 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 1,000 5,427E-03 0,03216194 GO:0002712|regulation of B cell mediated immunity, ! antigen receptor-mediated signaling pathway GO:0050851 33 17 1,000 5,427E-03 0,03208292 ! positive regulation of caspase activity GO:0043280 95 55 2,000 5,633E-03 0,03321633 GO:0010952|positive regulation of peptidase activity, ! positive regulation of phospholipase activity GO:0010518 104 55 2,000 5,633E-03 0,03313512 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 6,079E-03 0,03567573 ! memory GO:0007613 31 18 1,000 6,079E-03 0,03558893 ! epidermis morphogenesis GO:0048730 40 18 1,000 6,079E-03 0,03550255 ! cell-substrate junction assembly GO:0007044 54 18 1,000 6,079E-03 0,03541658 ! response to fungus GO:0009620 21 18 1,000 6,079E-03 0,03533104 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 1,000 6,079E-03 0,0352459 ! regulation of immunoglobulin production GO:0002637 43 18 1,000 6,079E-03 0,03516118 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 2,000 6,223E-03 0,03590296 ! regulation of phospholipase activity GO:0010517 106 57 2,000 6,223E-03 0,03581706 ! positive regulation of lipase activity GO:0060193 108 58 2,000 6,531E-03 0,03750154 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 1,000 6,766E-03 0,0387569 ! lipid phosphorylation GO:0046834 35 19 1,000 6,766E-03 0,03866484 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 1,000 6,766E-03 0,03857321 ! forelimb morphogenesis GO:0035136 32 19 1,000 6,766E-03 0,03848202 ! regulation of postsynaptic membrane potential GO:0060078 32 19 1,000 6,766E-03 0,03839126 ! pigmentation during development GO:0048066 41 19 1,000 6,766E-03 0,03830093 ! neuromuscular junction development GO:0007528 34 19 1,000 6,766E-03 0,03821102 ! plasma membrane fusion GO:0045026 28 19 1,000 6,766E-03 0,03812154 ! regulation of endothelial cell migration GO:0010594 44 19 1,000 6,766E-03 0,03803247 ! visual learning GO:0008542 36 19 1,000 6,766E-03 0,03794381 ! cellular pigmentation GO:0033059 36 19 1,000 6,766E-03 0,03785557 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 1,000 6,766E-03 0,03776774 ! integrin-mediated signaling pathway GO:0007229 135 59 2,000 6,848E-03 0,03813955 ! establishment of organelle localization GO:0051656 109 59 2,000 6,848E-03 0,03805147 ! regulation of heart contraction GO:0008016 110 60 2,000 7,174E-03 0,03977214 ! protein amino acid acetylation GO:0006473 39 20 1,000 7,485E-03 0,04140039 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 1,000 7,485E-03 0,04130543 ! transcription from RNA polymerase III promoter GO:0006383 41 20 1,000 7,485E-03 0,04121091 ! response to alkaloid GO:0043279 38 20 1,000 7,485E-03 0,04111682 ! regulation of fatty acid metabolic process GO:0019217 38 20 1,000 7,485E-03 0,04102316 ! regulation of interleukin-2 production GO:0032663 35 20 1,000 7,485E-03 0,04092993 ! sensory perception of pain GO:0019233 30 20 1,000 7,485E-03 0,04083711 ! diencephalon development GO:0021536 34 20 1,000 7,485E-03 0,04074472 ! negative regulation of angiogenesis GO:0016525 45 20 1,000 7,485E-03 0,04065275 ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 1,000 7,485E-03 0,04056119 ! inner ear receptor cell differentiation GO:0060113 37 20 1,000 7,485E-03 0,04047004 ! negative regulation of T cell activation GO:0050868 40 20 1,000 7,485E-03 0,0403793 ! negative regulation of translation GO:0017148 29 20 1,000 7,485E-03 0,04028897 ! mesoderm development GO:0007498 119 61 2,000 7,509E-03 0,0403298 ! viral reproductive process GO:0022415 126 62 2,000 7,854E-03 0,04208542 ! gonad development GO:0008406 98 62 2,000 7,854E-03 0,0419919 ! regulation of cell killing GO:0031341 42 21 1,000 8,238E-03 0,04394623 ! hindlimb morphogenesis GO:0035137 43 21 1,000 8,238E-03 0,04384901 ! ovarian follicle development GO:0001541 35 21 1,000 8,238E-03 0,04375221 ! cell aging GO:0007569 44 21 1,000 8,238E-03 0,04365584 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 1,000 8,238E-03 0,04355989 ! regulation of vasoconstriction GO:0019229 39 21 1,000 8,238E-03 0,04346437 ! oogenesis GO:0048477 36 21 1,000 8,238E-03 0,04336926 ! response to cytokine stimulus GO:0034097 63 21 1,000 8,238E-03 0,04327457 ! gut development GO:0048565 39 21 1,000 8,238E-03 0,04318029 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 2,000 8,57E-03 0,04482602 ! myeloid cell differentiation GO:0030099 111 65 2,000 8,942E-03 0,04667078 ! regeneration GO:0031099 41 22 1,000 9,023E-03 0,04698819 ! calcium-independent cell-cell adhesion GO:0016338 30 22 1,000 9,023E-03 0,04688671 ! mechanoreceptor differentiation GO:0042490 40 22 1,000 9,023E-03 0,04678566 ! central nervous system neuron development GO:0021954 46 22 1,000 9,023E-03 0,04668504 ! positive regulation of cytoskeleton organization GO:0051495 48 22 1,000 9,023E-03 0,04658486 ! apoptotic nuclear changes GO:0030262 32 22 1,000 9,023E-03 0,04648511 ! ureteric bud development GO:0001657 43 22 1,000 9,023E-03 0,04638578 ! renal system process GO:0003014 41 22 1,000 9,023E-03 0,04628688 ! positive regulation of adaptive immune response GO:0002821 39 22 1,000 9,023E-03 0,0461884 ! positive regulation of intracellular transport GO:0032388 37 22 1,000 9,023E-03 0,04609033 ! response to glucocorticoid stimulus GO:0051384 38 22 1,000 9,023E-03 0,04599268 ! activation of JUN kinase activity GO:0007257 42 22 1,000 9,023E-03 0,04589545 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 1,000 9,023E-03 0,04579862 ! developmental maturation GO:0021700 116 66 2,000 9,324E-03 0,04722726 ! positive regulation of T cell activation GO:0050870 109 67 2,000 9,715E-03 0,04910343 ! positive regulation of DNA replication GO:0045740 43 23 1,000 9,84E-03 0,049632 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 9,84E-03 0,04952816 ! leukocyte adhesion GO:0007159 50 23 1,000 9,84E-03 0,04942476 ! visual behavior GO:0007632 42 23 1,000 9,84E-03 0,0493218 ! regulation of cell-matrix adhesion GO:0001952 78 23 1,000 9,84E-03 0,04921926 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 48 23 1,000 9,84E-03 0,04911714 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 1,000 9,84E-03 0,04901545 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 1,000 9,84E-03 0,04891418 ! purine ribonucleoside metabolic process GO:0046128 34 23 1,000 9,84E-03 0,04881332 GO:0042278|purine nucleoside metabolic process, ! regulation of viral reproduction GO:0050792 38 23 1,000 9,84E-03 0,04871288 ! platelet activation GO:0030168 37 23 1,000 9,84E-03 0,04861286 ! regulation of bone mineralization GO:0030500 49 23 1,000 9,84E-03 0,04851324 ! negative regulation of catabolic process GO:0009895 50 23 1,000 9,84E-03 0,04841403 ! acetyl-CoA catabolic process GO:0046356 36 23 1,000 9,84E-03 0,04831523 GO:0006099|tricarboxylic acid cycle, ! viral reproduction GO:0016032 134 68 2,000 0,01011479 0,04956455 ! regulation of lipase activity GO:0060191 130 68 2,000 0,01011479 0,04946381 ! positive regulation of fibroblast proliferation GO:0048146 43 24 1,000 0,01068845 0,05216312 ! regulation of cellular catabolic process GO:0031329 52 24 1,000 0,01068845 0,05205753 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 1,000 0,01068845 0,05195236 ! vesicle docking GO:0048278 47 24 1,000 0,01068845 0,05184762 ! multicellular organismal response to stress GO:0033555 49 24 1,000 0,01068845 0,0517433 ! central nervous system neuron differentiation GO:0021953 50 24 1,000 0,01068845 0,0516394 ! response to corticosteroid stimulus GO:0031960 41 24 1,000 0,01068845 0,05153591 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 1,000 0,01068845 0,05143284 GO:0002708|positive regulation of lymphocyte mediated immunity, ! pallium development GO:0021543 49 24 1,000 0,01068845 0,05133018 ! leukocyte homeostasis GO:0001776 44 24 1,000 0,01068845 0,05122793 ! protein tetramerization GO:0051262 52 24 1,000 0,01068845 0,05112608 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 1,000 0,01156831 0,05522491 ! myelination GO:0042552 45 25 1,000 0,01156831 0,05511555 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 1,000 0,01156831 0,05500663 ! regulation of smooth muscle contraction GO:0006940 43 25 1,000 0,01156831 0,05489813 ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 0,01156831 0,05479006 ! coenzyme catabolic process GO:0009109 39 25 1,000 0,01156831 0,05468242 ! negative regulation of cell development GO:0010721 73 25 1,000 0,01156831 0,0545752 GO:0050768|negative regulation of neurogenesis, ! regulation of biomineral formation GO:0070167 51 25 1,000 0,01156831 0,0544684 ! somitogenesis GO:0001756 43 25 1,000 0,01156831 0,05436202 ! immunoglobulin production GO:0002377 55 25 1,000 0,01156831 0,05425605 GO:0002440|production of molecular mediator of immune response, ! regulation of blood coagulation GO:0030193 40 25 1,000 0,01156831 0,05415049 ! neural tube closure GO:0001843 49 25 1,000 0,01156831 0,05404535 GO:0060606|tube closure, ! liver development GO:0001889 53 25 1,000 0,01156831 0,05394061 ! learning or memory GO:0007611 147 73 2,000 0,01225871 0,05704926 ! axon guidance GO:0007411 139 73 2,000 0,01225871 0,05693913 ! initiation of viral infection GO:0019059 57 26 1,000 0,01247889 0,0578501 ! acetyl-CoA metabolic process GO:0006084 39 26 1,000 0,01247889 0,05773885 ! molting cycle process GO:0022404 50 26 1,000 0,01247889 0,05762803 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 1,000 0,01247889 0,05751763 ! regulation of cellular ketone metabolic process GO:0010565 44 26 1,000 0,01247889 0,05740765 ! positive regulation of MAPKKK cascade GO:0043410 47 26 1,000 0,01247889 0,05729809 ! group transfer coenzyme metabolic process GO:0006752 47 26 1,000 0,01247889 0,05718895 ! positive regulation of JUN kinase activity GO:0043507 51 26 1,000 0,01247889 0,05708023 ! organelle localization GO:0051640 136 74 2,000 0,0127163 0,05805582 ! phosphoinositide-mediated signaling GO:0048015 131 75 2,000 0,01318356 0,06007507 ! lymphocyte differentiation GO:0030098 167 75 2,000 0,01318356 0,05996151 ! regulation of fibroblast proliferation GO:0048145 52 27 1,000 0,01341975 0,0609206 ! neuron fate commitment GO:0048663 48 27 1,000 0,01341975 0,06080587 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 1,000 0,01341975 0,06069158 ! protein amino acid acylation GO:0043543 55 27 1,000 0,01341975 0,06057771 ! male gonad development GO:0008584 44 27 1,000 0,01341975 0,06046427 ! primary neural tube formation GO:0014020 51 27 1,000 0,01341975 0,06035125 ! negative regulation of lymphocyte activation GO:0051250 53 27 1,000 0,01341975 0,06023865 ! development of primary sexual characteristics GO:0045137 124 76 2,000 0,01366052 0,06120522 ! regulation of catabolic process GO:0009894 161 76 2,000 0,01366052 0,06109145 ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 0,01439047 0,06423649 ! synaptogenesis GO:0007416 42 28 1,000 0,01439047 0,06411753 ! regulation of JUN kinase activity GO:0043506 58 28 1,000 0,01439047 0,06399901 ! protein oligomerization GO:0051259 139 78 2,000 0,01464364 0,0650048 ! regulation of synaptic transmission GO:0050804 134 79 2,000 0,01514985 0,06712808 ! catechol metabolic process GO:0009712 54 29 1,000 0,01539062 0,06806952 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! immune response-activating signal transduction GO:0002757 47 29 1,000 0,01539062 0,06794462 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 1,000 0,01539062 0,06782018 ! response to organic cyclic substance GO:0014070 55 29 1,000 0,01539062 0,0676962 ! cell fate determination GO:0001709 60 29 1,000 0,01539062 0,06757266 ! cellular response to extracellular stimulus GO:0031668 48 29 1,000 0,01539062 0,06744958 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 1,000 0,01539062 0,06732695 ! negative regulation of neuron apoptosis GO:0043524 56 29 1,000 0,01539062 0,06720476 ! tissue homeostasis GO:0001894 48 29 1,000 0,01539062 0,06708301 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 1,000 0,01539062 0,0669617 ! inorganic anion transport GO:0015698 138 80 2,000 0,01566586 0,0680362 ! regulation of adenylate cyclase activity GO:0045761 156 80 2,000 0,01566586 0,06791361 ! phenol metabolic process GO:0018958 55 30 1,000 0,01641977 0,07105389 ! membrane docking GO:0022406 61 30 1,000 0,01641977 0,07092632 ! cell junction assembly GO:0034329 78 30 1,000 0,01641977 0,07079922 ! negative regulation of protein kinase cascade GO:0010741 68 30 1,000 0,01641977 0,07067256 ! positive regulation of multicellular organism growth GO:0040018 51 30 1,000 0,01641977 0,07054636 ! ensheathment of neurons GO:0007272 57 30 1,000 0,01641977 0,07042061 GO:0008366|axon ensheathment, ! cofactor catabolic process GO:0051187 51 30 1,000 0,01641977 0,07029531 ! negative regulation of leukocyte activation GO:0002695 56 30 1,000 0,01641977 0,07017045 ! response to heat GO:0009408 50 30 1,000 0,01641977 0,07004603 ! regulation of cAMP biosynthetic process GO:0030817 161 82 2,000 0,01672733 0,07123176 ! regulation of cyclase activity GO:0031279 159 82 2,000 0,01672733 0,07110591 ! response to drug GO:0042493 143 82 2,000 0,01672733 0,0709805 ! regulation of lyase activity GO:0051339 160 83 2,000 0,01727282 0,0731662 ! inner ear morphogenesis GO:0042472 47 31 1,000 0,01747751 0,07390314 ! cholesterol homeostasis GO:0042632 53 31 1,000 0,01747751 0,07377349 GO:0055092|sterol homeostasis, ! ovulation cycle process GO:0022602 49 31 1,000 0,01747751 0,07364429 ! positive regulation of T cell proliferation GO:0042102 52 31 1,000 0,01747751 0,07351554 ! triglyceride metabolic process GO:0006641 43 31 1,000 0,01747751 0,07338724 ! positive regulation of immune effector process GO:0002699 67 31 1,000 0,01747751 0,07325938 ! regulation of cAMP metabolic process GO:0030814 168 84 2,000 0,01782817 0,07459927 ! regulation of transmission of nerve impulse GO:0051969 141 84 2,000 0,01782817 0,07446975 ! response to hydrogen peroxide GO:0042542 50 32 1,000 0,01856342 0,07740658 ! cholesterol transport GO:0030301 56 32 1,000 0,01856342 0,07727266 ! metanephros development GO:0001656 74 32 1,000 0,01856342 0,0771392 ! ovulation cycle GO:0042698 51 32 1,000 0,01856342 0,0770062 ! peripheral nervous system development GO:0007422 64 32 1,000 0,01856342 0,07687366 ! hindbrain development GO:0030902 61 32 1,000 0,01856342 0,07674158 ! positive regulation of catabolic process GO:0009896 64 32 1,000 0,01856342 0,07660994 ! amine biosynthetic process GO:0009309 138 86 2,000 0,0189685 0,0781476 ! tube morphogenesis GO:0035239 176 86 2,000 0,0189685 0,07801402 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 2,000 0,01955349 0,08028275 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! post-embryonic development GO:0009791 69 33 1,000 0,0196771 0,08065266 ! positive regulation of neurogenesis GO:0050769 67 33 1,000 0,0196771 0,08051549 ! sterol transport GO:0015918 57 33 1,000 0,0196771 0,08037879 ! regulation of neurological system process GO:0031644 148 88 2,000 0,02014838 0,08216439 ! regulation of cell adhesion GO:0030155 212 89 2,000 0,02075317 0,08448751 ! mismatch repair GO:0006298 46 34 1,000 0,02081814 0,08460886 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 2,000 0,02136786 0,08669659 ! female gonad development GO:0008585 58 35 1,000 0,02198613 0,08905494 ! neutral lipid metabolic process GO:0006638 50 35 1,000 0,02198613 0,08890527 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 1,000 0,02198613 0,0887561 ! calcium-mediated signaling GO:0019722 62 35 1,000 0,02198613 0,08860743 ! regulation of microtubule-based process GO:0032886 78 35 1,000 0,02198613 0,08845926 ! neural tube formation GO:0001841 67 35 1,000 0,02198613 0,08831158 ! regulation of defense response GO:0031347 149 92 2,000 0,02262698 0,0907342 ! cell junction organization GO:0034330 86 36 1,000 0,02318068 0,09279988 ! aerobic respiration GO:0009060 55 36 1,000 0,02318068 0,09264573 ! androgen receptor signaling pathway GO:0030521 74 36 1,000 0,02318068 0,09249209 ! negative regulation of cell activation GO:0050866 65 36 1,000 0,02318068 0,09233895 ! regulation of nucleotide metabolic process GO:0006140 182 93 2,000 0,02327141 0,09254711 ! glycerol ether metabolic process GO:0006662 53 37 1,000 0,0244014 0,09688081 ! regulation of protein stability GO:0031647 73 37 1,000 0,0244014 0,09672121 ! glycogen metabolic process GO:0005977 61 37 1,000 0,0244014 0,09656213 ! pigment metabolic process GO:0042440 80 37 1,000 0,0244014 0,09640357 ! carbohydrate homeostasis GO:0033500 53 38 1,000 0,02564789 0,10116202 GO:0042593|glucose homeostasis, ! development of primary female sexual characteristics GO:0046545 67 38 1,000 0,02564789 0,10099646 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 1,000 0,02564789 0,10083143 ! lipid homeostasis GO:0055088 67 38 1,000 0,02564789 0,10066694 ! nucleotide catabolic process GO:0009166 61 38 1,000 0,02564789 0,10050299 ! embryonic epithelial tube formation GO:0001838 72 38 1,000 0,02564789 0,10033957 ! glucan metabolic process GO:0044042 62 38 1,000 0,02564789 0,10017668 GO:0006073|cellular glucan metabolic process, ! regulation of DNA metabolic process GO:0051052 178 97 2,000 0,02594814 0,10118514 ! regulation of protein localization GO:0032880 176 97 2,000 0,02594814 0,10102141 ! ear morphogenesis GO:0042471 60 39 1,000 0,02691978 0,10463487 ! organic ether metabolic process GO:0018904 55 39 1,000 0,02691978 0,1044661 ! development of primary male sexual characteristics GO:0046546 66 39 1,000 0,02691978 0,10429788 ! segmentation GO:0035282 67 39 1,000 0,02691978 0,1041302 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 1,000 0,02691978 0,10396306 ! regulation of action potential in neuron GO:0019228 73 39 1,000 0,02691978 0,10379645 ! Rho protein signal transduction GO:0007266 74 39 1,000 0,02691978 0,10363037 ! mesenchymal cell development GO:0014031 87 40 1,000 0,02821667 0,10844936 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 1,000 0,02821667 0,1082764 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 1,000 0,02953819 0,113167 ! female gamete generation GO:0007292 61 41 1,000 0,02953819 0,11298709 ! dorsal/ventral pattern formation GO:0009953 68 41 1,000 0,02953819 0,11280774 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 1,000 0,02953819 0,11262897 ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 0,03088396 0,11757407 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 1,000 0,03088396 0,11738833 ! regulation of intracellular protein transport GO:0033157 80 42 1,000 0,03088396 0,11720318 ! regulation of leukocyte mediated immunity GO:0002703 79 42 1,000 0,03088396 0,11701861 ! neuron migration GO:0001764 79 42 1,000 0,03088396 0,11683461 ! energy reserve metabolic process GO:0006112 74 43 1,000 0,03225362 0,12182452 ! neural tube development GO:0021915 77 43 1,000 0,03225362 0,12163357 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,03228282 0,12155315 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,03228282 0,12136322 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,03228282 0,12117389 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,03228282 0,12098514 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,03228282 0,12079699 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,03228282 0,12060941 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,03228282 0,12042242 ! polyol transport GO:0015791 12 5 0,000 0,03228282 0,12023601 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,03228282 0,12005017 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,03228282 0,11986491 ! response to superoxide GO:0000303 10 5 0,000 0,03228282 0,11968022 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,03228282 0,1194961 GO:0045940|positive regulation of steroid metabolic process, ! tongue development GO:0043586 8 5 0,000 0,03228282 0,11931254 ! female meiosis GO:0007143 7 5 0,000 0,03228282 0,11912954 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,03228282 0,11894711 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,03228282 0,11876523 ! cobalt ion transport GO:0006824 11 5 0,000 0,03228282 0,11858391 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,03228282 0,11840314 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,03228282 0,11822293 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,03228282 0,11804326 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,03228282 0,11786413 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,03228282 0,11768555 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,03228282 0,11750751 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,03228282 0,11733 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,03228282 0,11715304 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,03228282 0,1169766 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,03228282 0,1168007 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,03228282 0,11662532 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,03228282 0,11645047 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,03228282 0,11627614 ! negative chemotaxis GO:0050919 14 5 0,000 0,03228282 0,11610234 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,03228282 0,11592905 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,03228282 0,11575628 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,03228282 0,11558402 ! behavioral response to pain GO:0048266 9 5 0,000 0,03228282 0,11541228 ! clathrin coat assembly GO:0048268 14 5 0,000 0,03228282 0,11524104 ! Notch receptor processing GO:0007220 8 5 0,000 0,03228282 0,11507031 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,03228282 0,11490009 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! micturition GO:0060073 9 5 0,000 0,03228282 0,11473037 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,03228282 0,11456115 ! copulation GO:0007620 9 5 0,000 0,03228282 0,11439243 ! glial cell fate commitment GO:0021781 13 5 0,000 0,03228282 0,11422421 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,03228282 0,11405648 ! spermidine metabolic process GO:0008216 7 5 0,000 0,03228282 0,11388924 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,03228282 0,11372249 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,03228282 0,11355623 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,03228282 0,11339046 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,03228282 0,11322516 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,03228282 0,11306035 ! grooming behavior GO:0007625 6 5 0,000 0,03228282 0,11289602 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,03228282 0,11273217 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,03228282 0,11256879 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,03228282 0,11240588 ! response to protozoan GO:0001562 10 5 0,000 0,03228282 0,11224344 ! lymph vessel development GO:0001945 10 5 0,000 0,03228282 0,11208148 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,03228282 0,11191997 ! endochondral ossification GO:0001958 16 5 0,000 0,03228282 0,11175894 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,03228282 0,11159837 ! anagen GO:0042640 6 5 0,000 0,03228282 0,11143825 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,03228282 0,1112786 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,03228282 0,1111194 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,03228282 0,11096066 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,03228282 0,11080237 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,03228282 0,11064453 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,03228282 0,11048714 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,03228282 0,1103302 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,03228282 0,11017371 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,03228282 0,11001765 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,03228282 0,10986204 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,03228282 0,10970687 GO:0046516|hypusine metabolic process, ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,03228282 0,10955213 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,03228282 0,10939783 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,03228282 0,10924397 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,03228282 0,10909054 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,03228282 0,10893754 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,03228282 0,10878496 ! histidine catabolic process GO:0006548 6 5 0,000 0,03228282 0,10863281 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,03228282 0,10848109 ! valine metabolic process GO:0006573 10 5 0,000 0,03228282 0,10832979 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,03228282 0,10817892 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,03228282 0,10802846 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,03228282 0,10787842 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,03228282 0,1077288 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,03228282 0,10757959 ! polyol catabolic process GO:0046174 7 5 0,000 0,03228282 0,10743079 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,03228282 0,10728241 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,03228282 0,10713443 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,03228282 0,10698686 ! muscle cell migration GO:0014812 8 5 0,000 0,03228282 0,1068397 ! mitochondrial fission GO:0000266 8 5 0,000 0,03228282 0,10669294 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,03228282 0,10654659 ! mRNA transcription GO:0009299 9 5 0,000 0,03228282 0,10640063 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,03228282 0,10625508 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,03228282 0,10610992 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,03228282 0,10596516 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,03228282 0,10582079 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,03228282 0,10567682 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,03228282 0,10553324 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,03228282 0,10539004 ! response to food GO:0032094 6 5 0,000 0,03228282 0,10524724 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,03228282 0,10510482 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,03228282 0,10496279 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,03228282 0,10482114 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,03228282 0,10467987 ! forebrain neuron development GO:0021884 13 5 0,000 0,03228282 0,10453898 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,03228282 0,10439847 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,03228282 0,10425834 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,03228282 0,10411858 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,03228282 0,1039792 GO:0009251|glucan catabolic process, ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,03228282 0,10384019 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,03228282 0,10370155 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,03228282 0,10356328 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,03228282 0,10342538 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,03228282 0,10328785 ! basic amino acid transport GO:0015802 11 5 0,000 0,03228282 0,10315068 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,03228282 0,10301388 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,03228282 0,10287743 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,03228282 0,10274135 ! depyrimidination GO:0045008 10 5 0,000 0,03228282 0,10260563 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,03228282 0,10247027 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,03228282 0,10233526 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,03228282 0,10220061 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 0,03228282 0,10206631 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,03228282 0,10193237 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,03228282 0,10179877 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,03228282 0,10166553 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,03228282 0,10153263 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,03228282 0,10140008 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,03228282 0,10126788 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,03228282 0,10113602 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,03228282 0,1010045 ! response to arsenic GO:0046685 10 5 0,000 0,03228282 0,10087333 ! mast cell degranulation GO:0043303 7 5 0,000 0,03228282 0,10074249 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,03228282 0,100612 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,03228282 0,10048184 ! response to cadmium ion GO:0046686 7 5 0,000 0,03228282 0,10035202 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,03228282 0,10022253 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,03228282 0,10009338 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,03228282 0,09996456 ! decidualization GO:0046697 11 5 0,000 0,03228282 0,09983607 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,03228282 0,09970791 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,03228282 0,09958008 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,03228282 0,09945258 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,03228282 0,0993254 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,03228282 0,09919855 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,03228282 0,09907202 ! neural tube patterning GO:0021532 7 5 0,000 0,03228282 0,09894581 ! embryonic cleavage GO:0040016 6 5 0,000 0,03228282 0,09881993 ! peroxisome fission GO:0016559 5 5 0,000 0,03228282 0,09869436 ! histone demethylation GO:0016577 10 5 0,000 0,03228282 0,09856911 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,03228282 0,09844419 ! mitotic recombination GO:0006312 9 5 0,000 0,03228282 0,09831957 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,03228282 0,09819528 ! metaphase plate congression GO:0051310 7 5 0,000 0,03228282 0,09807129 ! regulation of sterol transport GO:0032371 7 5 0,000 0,03228282 0,09794762 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,03228282 0,09782426 ! enteric nervous system development GO:0048484 8 5 0,000 0,03228282 0,09770121 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,03228282 0,09757847 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,03228282 0,09745604 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,03228282 0,09733391 ! muscle cell proliferation GO:0033002 11 5 0,000 0,03228282 0,09721209 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,03228282 0,09709058 ! plasminogen activation GO:0031639 5 5 0,000 0,03228282 0,09696937 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,03228282 0,09684846 ! metaphase GO:0051323 8 5 0,000 0,03228282 0,09672785 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,03228282 0,09660754 ! cellular response to nutrient GO:0031670 8 5 0,000 0,03228282 0,09648753 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,03228282 0,09636782 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,03228282 0,0962484 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,03228282 0,09612929 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,03228282 0,09601046 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,03228282 0,09589193 ! response to redox state GO:0051775 5 5 0,000 0,03228282 0,09577369 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,03228282 0,09565574 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,03228282 0,09553808 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,03228282 0,09542072 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,03228282 0,09530364 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,03228282 0,09518684 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,03228282 0,09507033 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,03228282 0,09495411 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,03228282 0,09483817 ! striatum development GO:0021756 9 5 0,000 0,03228282 0,09472252 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,03228282 0,09460714 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,03228282 0,09449205 ! glial cell migration GO:0008347 11 5 0,000 0,03228282 0,09437723 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,03228282 0,0942627 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,03228282 0,09414844 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,03228282 0,09403446 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,03228282 0,09392075 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,03228282 0,09380732 ! neuroprotection GO:0043526 6 5 0,000 0,03228282 0,09369416 ! neural plate development GO:0001840 8 5 0,000 0,03228282 0,09358128 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,03228282 0,09346867 GO:0046831|regulation of RNA export from nucleus, ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,03228282 0,09335633 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,03228282 0,09324425 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,03228282 0,09313245 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,03228282 0,09302091 ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,03228282 0,09290964 ! spindle assembly GO:0051225 6 5 0,000 0,03228282 0,09279864 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,03228282 0,0926879 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,03228282 0,09257743 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,03228282 0,09246722 ! drug metabolic process GO:0017144 6 5 0,000 0,03228282 0,09235727 ! stem cell division GO:0017145 11 5 0,000 0,03228282 0,09224758 GO:0048103|somatic stem cell division, ! organ regeneration GO:0031100 7 5 0,000 0,03228282 0,09213815 ! carnitine metabolic process GO:0009437 7 5 0,000 0,03228282 0,09202898 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,03228282 0,09192007 ! B cell differentiation GO:0030183 107 44 1,000 0,0336468 0,09569055 ! developmental growth GO:0048589 82 44 1,000 0,0336468 0,09557758 ! glycolysis GO:0006096 65 45 1,000 0,03506314 0,09948339 ! regulation of JAK-STAT cascade GO:0046425 70 45 1,000 0,03506314 0,09936621 ! detection of stimulus involved in sensory perception GO:0050906 66 45 1,000 0,03506314 0,09924931 ! branching morphogenesis of a tube GO:0048754 97 45 1,000 0,03506314 0,09913268 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 1,000 0,03506314 0,09901633 ! cell growth GO:0016049 84 45 1,000 0,03506314 0,09890025 ! positive regulation of protein transport GO:0051222 72 46 1,000 0,03650227 0,10283895 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 1,000 0,03650227 0,10271867 ! regulation of gene-specific transcription GO:0032583 96 46 1,000 0,03650227 0,10259867 ! positive regulation of DNA binding GO:0043388 73 47 1,000 0,03796384 0,10658227 ! vascular process in circulatory system GO:0003018 80 47 1,000 0,03796384 0,10645805 ! regulation of JNK cascade GO:0046328 94 47 1,000 0,03796384 0,10633412 ! protein homooligomerization GO:0051260 76 47 1,000 0,03796384 0,10621047 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,03861386 0,10790354 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,03861386 0,10777836 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,03861386 0,10765347 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,03861386 0,10752887 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,03861386 0,10740456 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,03861386 0,10728054 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,03861386 0,1071568 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,03861386 0,10703335 ! response to oxygen radical GO:0000305 11 6 0,000 0,03861386 0,10691018 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,03861386 0,10678729 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,03861386 0,10666469 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,03861386 0,10654237 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,03861386 0,10642033 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,03861386 0,10629856 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,03861386 0,10617708 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,03861386 0,10605587 ! forebrain regionalization GO:0021871 8 6 0,000 0,03861386 0,10593494 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,03861386 0,10581429 ! male meiosis GO:0007140 7 6 0,000 0,03861386 0,10569391 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,03861386 0,1055738 ! response to zinc ion GO:0010043 9 6 0,000 0,03861386 0,10545397 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,03861386 0,10533441 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,03861386 0,10521511 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,03861386 0,10509609 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,03861386 0,10497734 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,03861386 0,10485885 ! malate metabolic process GO:0006108 11 6 0,000 0,03861386 0,10474064 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,03861386 0,10462269 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,03861386 0,104505 ! protein refolding GO:0042026 15 6 0,000 0,03861386 0,10438758 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,03861386 0,10427042 ! opsonization GO:0008228 8 6 0,000 0,03861386 0,10415353 ! mating behavior GO:0007617 7 6 0,000 0,03861386 0,10403689 ! neuron remodeling GO:0016322 15 6 0,000 0,03861386 0,10392052 ! erythrocyte maturation GO:0043249 7 6 0,000 0,03861386 0,10380441 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,03861386 0,10368856 ! equilibrioception GO:0050957 14 6 0,000 0,03861386 0,10357296 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,03861386 0,10345762 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,03861386 0,10334254 ! photoreceptor cell development GO:0042461 10 6 0,000 0,03861386 0,10322772 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,03861386 0,10311315 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,03861386 0,10299883 ! response to interferon-gamma GO:0034341 15 6 0,000 0,03861386 0,10288477 ! toxin metabolic process GO:0009404 11 6 0,000 0,03861386 0,10277096 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,03861386 0,1026574 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,03861386 0,10254409 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,03861386 0,10243103 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,03861386 0,10231822 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,03861386 0,10220566 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,03861386 0,10209335 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,03861386 0,10198128 ! protein lipoylation GO:0009249 10 6 0,000 0,03861386 0,10186946 ! cysteine metabolic process GO:0006534 10 6 0,000 0,03861386 0,10175788 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,03861386 0,10164655 ! glutamate catabolic process GO:0006538 10 6 0,000 0,03861386 0,10153546 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,03861386 0,10142461 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,03861386 0,10131401 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,03861386 0,10120364 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,03861386 0,10109352 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,03861386 0,10098364 ! hyperosmotic response GO:0006972 9 6 0,000 0,03861386 0,10087399 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,03861386 0,10076458 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,03861386 0,10065541 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,03861386 0,10054648 ! urea metabolic process GO:0019627 7 6 0,000 0,03861386 0,10043778 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,03861386 0,10032931 ! neutrophil activation GO:0042119 8 6 0,000 0,03861386 0,10022108 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,03861386 0,10011309 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,03861386 0,10000532 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,03861386 0,09989779 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,03861386 0,09979049 ! nucleoside salvage GO:0043174 9 6 0,000 0,03861386 0,09968342 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,03861386 0,09957658 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,03861386 0,09946996 ! T cell mediated immunity GO:0002456 16 6 0,000 0,03861386 0,09936358 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,03861386 0,09925742 GO:0010543|regulation of platelet activation, ! carnitine transport GO:0015879 10 6 0,000 0,03861386 0,09915149 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,03861386 0,09904578 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,03861386 0,0989403 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,03861386 0,09883505 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,03861386 0,09873002 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,03861386 0,09862521 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,03861386 0,09852062 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,03861386 0,09841626 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,03861386 0,09831211 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,03861386 0,09820819 ! establishment of spindle localization GO:0051293 12 6 0,000 0,03861386 0,09810448 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,03861386 0,098001 ! monocyte differentiation GO:0030224 12 6 0,000 0,03861386 0,09789773 ! response to UV-C GO:0010225 11 6 0,000 0,03861386 0,09779468 ! astrocyte development GO:0014002 15 6 0,000 0,03861386 0,09769185 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,03861386 0,09758923 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,03861386 0,09748683 ! interaction with symbiont GO:0051702 13 6 0,000 0,03861386 0,09738464 ! regulation of dendrite development GO:0050773 16 6 0,000 0,03861386 0,09728267 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,03861386 0,09718091 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,03861386 0,09707936 ! response to copper ion GO:0046688 10 6 0,000 0,03861386 0,09697802 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,03861386 0,0968769 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,03861386 0,09677598 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,03861386 0,09667528 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,03861386 0,09657479 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,03861386 0,0964745 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,03861386 0,09637442 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,03861386 0,09627455 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,03861386 0,09617489 ! hair follicle maturation GO:0048820 7 6 0,000 0,03861386 0,09607543 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,03861386 0,09597618 ! Schwann cell development GO:0014044 15 6 0,000 0,03861386 0,09587714 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,03861386 0,09577829 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,03861386 0,09567966 ! subpallium development GO:0021544 10 6 0,000 0,03861386 0,09558122 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,03861386 0,09548299 ! histone ubiquitination GO:0016574 8 6 0,000 0,03861386 0,09538495 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,03861386 0,09528712 ! maintenance of organ identity GO:0048496 9 6 0,000 0,03861386 0,09518949 ! G2 phase GO:0051319 16 6 0,000 0,03861386 0,09509206 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,03861386 0,09499483 ! establishment of planar polarity GO:0001736 7 6 0,000 0,03861386 0,0948978 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,03861386 0,09480096 ! membrane to membrane docking GO:0022614 14 6 0,000 0,03861386 0,09470433 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,03861386 0,09460789 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,03861386 0,09451164 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,03861386 0,09441559 ! receptor internalization GO:0031623 10 6 0,000 0,03861386 0,09431974 ! neutrophil homeostasis GO:0001780 10 6 0,000 0,03861386 0,09422408 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,03861386 0,09412862 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,03861386 0,09403335 ! protein deubiquitination GO:0016579 14 6 0,000 0,03861386 0,09393827 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 0,03861386 0,09384338 ! protein destabilization GO:0031648 9 6 0,000 0,03861386 0,09374868 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,03861386 0,09365418 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,03861386 0,09355986 ! regulation of viral transcription GO:0046782 10 6 0,000 0,03861386 0,09346574 ! progesterone metabolic process GO:0042448 10 6 0,000 0,03861386 0,0933718 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,03861386 0,09327806 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,03861386 0,0931845 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,03861386 0,09309113 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,03861386 0,09299794 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,03861386 0,09290495 ! determination of adult lifespan GO:0008340 15 6 0,000 0,03861386 0,09281213 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,03861386 0,09271951 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,03861386 0,09262706 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,03861386 0,09253481 ! catecholamine transport GO:0051937 9 6 0,000 0,03861386 0,09244273 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,03861386 0,09235084 ! sensory cilium assembly GO:0035058 10 6 0,000 0,03861386 0,09225913 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,03861386 0,0921676 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,03861386 0,09207626 ! maternal placenta development GO:0001893 12 6 0,000 0,03861386 0,09198509 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,03861386 0,09189411 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,03861386 0,09180331 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,03861386 0,09171268 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,03861386 0,09162223 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,03861386 0,09153197 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,03861386 0,09144188 ! Notch signaling pathway GO:0007219 96 48 1,000 0,03944751 0,09332419 ! morphogenesis of embryonic epithelium GO:0016331 91 48 1,000 0,03944751 0,09323251 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 1,000 0,03944751 0,09314102 ! regulation of action potential GO:0001508 95 49 1,000 0,04095291 0,09660068 ! detection of abiotic stimulus GO:0009582 74 49 1,000 0,04095291 0,09650607 ! neuromuscular process GO:0050905 99 50 1,000 0,04247971 0,10000604 ! histone modification GO:0016570 91 50 1,000 0,04247971 0,09990829 ! positive regulation of binding GO:0051099 78 51 1,000 0,04402756 0,10344757 ! response to estrogen stimulus GO:0043627 93 51 1,000 0,04402756 0,10334665 ! viral infectious cycle GO:0019058 99 51 1,000 0,04402756 0,10324592 ! embryonic skeletal system development GO:0048706 85 51 1,000 0,04402756 0,10314539 ! chromatin remodeling GO:0006338 109 51 1,000 0,04402756 0,10304505 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 1,000 0,04402756 0,10294491 ! regulation of cell shape GO:0008360 125 51 1,000 0,04402756 0,10284496 ! tRNA transcription GO:0009304 14 7 0,000 0,04490369 0,10478979 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,04490369 0,10468825 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,04490369 0,10458691 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,04490369 0,10448576 ! regulation of helicase activity GO:0051095 15 7 0,000 0,04490369 0,10438481 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,04490369 0,10428405 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,04490369 0,10418349 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,04490369 0,10408312 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,04490369 0,10398294 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,04490369 0,10388296 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,04490369 0,10378317 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,04490369 0,10368357 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,04490369 0,10358416 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,04490369 0,10348494 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,04490369 0,10338591 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,04490369 0,10328707 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,04490369 0,10318842 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,04490369 0,10308996 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,04490369 0,10299168 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,04490369 0,1028936 ! glycolipid transport GO:0046836 10 7 0,000 0,04490369 0,1027957 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,04490369 0,10269798 GO:0051923|sulfation, ! neuron adhesion GO:0007158 12 7 0,000 0,04490369 0,10260045 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,04490369 0,10250311 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,04490369 0,10240595 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,04490369 0,10230897 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,04490369 0,10221218 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,04490369 0,10211557 ! pericardium development GO:0060039 14 7 0,000 0,04490369 0,10201915 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,04490369 0,1019229 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,04490369 0,10182684 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,04490369 0,10173096 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,04490369 0,10163526 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,04490369 0,10153973 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,04490369 0,10144439 ! lipoprotein transport GO:0042953 14 7 0,000 0,04490369 0,10134923 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,04490369 0,10125424 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,04490369 0,10115943 ! rhythmic behavior GO:0007622 15 7 0,000 0,04490369 0,1010648 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,04490369 0,10097035 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,04490369 0,10087607 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,04490369 0,10078197 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,04490369 0,10068805 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,04490369 0,1005943 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,04490369 0,10050072 ! mechanosensory behavior GO:0007638 14 7 0,000 0,04490369 0,10040732 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,04490369 0,10031409 ! positive regulation of heart rate GO:0010460 10 7 0,000 0,04490369 0,10022104 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,04490369 0,10012815 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,04490369 0,10003544 ! spinal cord patterning GO:0021511 13 7 0,000 0,04490369 0,0999429 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,04490369 0,09985053 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,04490369 0,09975833 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,04490369 0,09966631 ! adrenal gland development GO:0030325 17 7 0,000 0,04490369 0,09957445 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,04490369 0,09948276 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,04490369 0,09939124 ! ovulation GO:0030728 9 7 0,000 0,04490369 0,09929989 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,04490369 0,0992087 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,04490369 0,09911768 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,04490369 0,09902683 ! microtubule nucleation GO:0007020 20 7 0,000 0,04490369 0,09893615 ! proline biosynthetic process GO:0006561 10 7 0,000 0,04490369 0,09884563 ! thyroid hormone generation GO:0006590 13 7 0,000 0,04490369 0,09875528 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,04490369 0,09866509 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,04490369 0,09857507 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,04490369 0,09848521 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,04490369 0,09839552 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,04490369 0,09830598 ! galactose metabolic process GO:0006012 13 7 0,000 0,04490369 0,09821661 ! response to dietary excess GO:0002021 8 7 0,000 0,04490369 0,09812741 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,04490369 0,09803836 ! intracellular pH reduction GO:0051452 11 7 0,000 0,04490369 0,09794948 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,04490369 0,09786076 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,04490369 0,0977722 ! purine salvage GO:0043101 10 7 0,000 0,04490369 0,09768379 ! nucleoside transport GO:0015858 8 7 0,000 0,04490369 0,09759555 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,04490369 0,09750747 ! parturition GO:0007567 14 7 0,000 0,04490369 0,09741955 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,04490369 0,09733178 ! rRNA modification GO:0000154 14 7 0,000 0,04490369 0,09724417 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,04490369 0,09715672 ! spindle checkpoint GO:0031577 15 7 0,000 0,04490369 0,09706943 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,04490369 0,09698229 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,04490369 0,09689532 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,04490369 0,09680849 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,04490369 0,09672182 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,04490369 0,09663531 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,04490369 0,09654895 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 0,04490369 0,09646275 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,04490369 0,0963767 ! fibrinolysis GO:0042730 10 7 0,000 0,04490369 0,0962908 ! eating behavior GO:0042755 7 7 0,000 0,04490369 0,09620505 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,04490369 0,09611946 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,04490369 0,09603402 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,04490369 0,09594874 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,04490369 0,0958636 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,04490369 0,09577861 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,04490369 0,09569378 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,04490369 0,09560909 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,04490369 0,09552456 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,04490369 0,09544017 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,04490369 0,09535594 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,04490369 0,09527185 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,04490369 0,09518791 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,04490369 0,09510412 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,04490369 0,09502047 ! regulation of meiosis GO:0040020 12 7 0,000 0,04490369 0,09493697 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,04490369 0,09485362 ! regulation of lipid transport GO:0032368 14 7 0,000 0,04490369 0,09477042 ! oxygen homeostasis GO:0032364 12 7 0,000 0,04490369 0,09468736 ! transcription termination GO:0006353 13 7 0,000 0,04490369 0,09460445 ! response to tumor cell GO:0002347 13 7 0,000 0,04490369 0,09452168 ! anaphase GO:0051322 17 7 0,000 0,04490369 0,09443905 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,04490369 0,09435657 ! axonal fasciculation GO:0007413 18 7 0,000 0,04490369 0,09427424 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,04490369 0,09419205 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,04490369 0,09411 ! diuresis GO:0030146 12 7 0,000 0,04490369 0,09402809 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,04490369 0,09394633 ! thiamin metabolic process GO:0006772 7 7 0,000 0,04490369 0,09386471 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,04490369 0,09378323 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,04490369 0,09370189 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,04490369 0,09362069 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,04490369 0,09353963 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,04490369 0,09345872 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,04490369 0,09337794 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,04490369 0,0932973 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,04490369 0,0932168 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,04490369 0,09313645 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,04490369 0,09305622 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 10 7 0,000 0,04490369 0,09297614 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,04490369 0,0928962 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,04490369 0,09281639 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,04490369 0,09273672 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,04490369 0,09265718 ! adult feeding behavior GO:0008343 9 7 0,000 0,04490369 0,09257779 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,04490369 0,09249852 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,04490369 0,0924194 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,04490369 0,09234041 ! muscle adaptation GO:0043500 14 7 0,000 0,04490369 0,09226155 ! embryonic heart tube development GO:0035050 10 7 0,000 0,04490369 0,09218283 ! retina homeostasis GO:0001895 12 7 0,000 0,04490369 0,09210424 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,04490369 0,09202579 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,04490369 0,09194747 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,04490369 0,09186928 ! protein prenylation GO:0018342 18 7 0,000 0,04490369 0,09179123 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,04490369 0,09171331 ! covalent chromatin modification GO:0016569 101 52 1,000 0,04559613 0,0930486 ! morphogenesis of a branching structure GO:0001763 111 52 1,000 0,04559613 0,09296974 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 1,000 0,04718509 0,09612813 ! cell maturation GO:0048469 100 53 1,000 0,04718509 0,0960468 ! regulation of neuron apoptosis GO:0043523 100 53 1,000 0,04718509 0,09596561 ! regulation of protein polymerization GO:0032271 103 53 1,000 0,04718509 0,09588456 ! cell recognition GO:0008037 85 54 1,000 0,04879409 0,09907054 ! chloride transport GO:0006821 90 55 1,000 0,05042283 0,10229116 ! glucose catabolic process GO:0006007 82 55 1,000 0,05042283 0,10220499 ! cellular polysaccharide metabolic process GO:0044264 86 55 1,000 0,05042283 0,10211896 ! regulation of protein catabolic process GO:0042176 116 55 1,000 0,05042283 0,10203307 ! aging GO:0007568 103 55 1,000 0,05042283 0,10194733 ! heart morphogenesis GO:0003007 97 55 1,000 0,05042283 0,10186173 ! regulation of multicellular organism growth GO:0040014 85 55 1,000 0,05042283 0,10177628 ! nuclear export GO:0051168 97 55 1,000 0,05042283 0,10169096 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,05115258 0,1030763 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,05115258 0,10299004 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,05115258 0,10290393 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,05115258 0,10281796 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,05115258 0,10273213 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,05115258 0,10264645 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,05115258 0,10256091 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,05115258 0,10247552 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,05115258 0,10239026 ! meiotic prophase I GO:0007128 13 8 0,000 0,05115258 0,10230515 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,05115258 0,10222018 ! oligopeptide transport GO:0006857 15 8 0,000 0,05115258 0,10213535 ! UTP metabolic process GO:0046051 8 8 0,000 0,05115258 0,10205066 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,05115258 0,10196611 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,05115258 0,1018817 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,05115258 0,10179743 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,05115258 0,1017133 ! succinate metabolic process GO:0006105 14 8 0,000 0,05115258 0,10162931 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,05115258 0,10154546 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,05115258 0,10146175 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,05115258 0,10137817 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,05115258 0,10129473 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,05115258 0,10121143 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,05115258 0,10112826 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,05115258 0,10104524 ! reflex GO:0060004 16 8 0,000 0,05115258 0,10096234 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,05115258 0,10087959 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,05115258 0,10079697 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,05115258 0,10071448 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,05115258 0,10063213 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,05115258 0,10054992 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,05115258 0,10046783 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,05115258 0,10038589 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,05115258 0,10030407 ! astrocyte differentiation GO:0048708 18 8 0,000 0,05115258 0,10022239 ! histidine metabolic process GO:0006547 16 8 0,000 0,05115258 0,10014084 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,05115258 0,10005943 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,05115258 0,09997815 ! glycine catabolic process GO:0006546 13 8 0,000 0,05115258 0,09989699 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,05115258 0,09981598 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,05115258 0,09973509 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,05115258 0,09965433 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,05115258 0,0995737 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,05115258 0,09949321 ! macrophage activation GO:0042116 12 8 0,000 0,05115258 0,09941284 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,05115258 0,0993326 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,05115258 0,0992525 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,05115258 0,09917252 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,05115258 0,09909267 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,05115258 0,09901295 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,05115258 0,09893336 ! osteoblast development GO:0002076 16 8 0,000 0,05115258 0,09885389 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,05115258 0,09877456 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,05115258 0,09869535 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,05115258 0,09861626 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,05115258 0,09853731 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,05115258 0,09845848 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,05115258 0,09837977 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,05115258 0,0983012 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,05115258 0,09822274 ! intermediate filament organization GO:0045109 12 8 0,000 0,05115258 0,09814442 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,05115258 0,09806621 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,05115258 0,09798813 ! cellular extravasation GO:0045123 12 8 0,000 0,05115258 0,09791018 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,05115258 0,09783235 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,05115258 0,09775464 ! response to antibiotic GO:0046677 11 8 0,000 0,05115258 0,09767706 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,05115258 0,0975996 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,05115258 0,09752226 ! DNA topological change GO:0006265 12 8 0,000 0,05115258 0,09744505 ! response to tropane GO:0014073 15 8 0,000 0,05115258 0,09736796 GO:0042220|response to cocaine, ! melanosome transport GO:0032402 13 8 0,000 0,05115258 0,09729099 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,05115258 0,09721414 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,05115258 0,09713741 ! mast cell activation GO:0045576 14 8 0,000 0,05115258 0,0970608 ! multicellular organismal aging GO:0010259 18 8 0,000 0,05115258 0,09698432 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,05115258 0,09690795 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,05115258 0,09683171 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,05115258 0,09675558 ! nucleosome disassembly GO:0006337 14 8 0,000 0,05115258 0,09667957 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,05115258 0,09660369 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,05115258 0,09652792 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,05115258 0,09645227 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,05115258 0,09637674 GO:0050000|chromosome localization, ! intracellular lipid transport GO:0032365 13 8 0,000 0,05115258 0,09630133 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,05115258 0,09622603 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of macrophage activation GO:0043030 15 8 0,000 0,05115258 0,09615086 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,05115258 0,0960758 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,05115258 0,09600086 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,05115258 0,09592603 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,05115258 0,09585132 ! hormone catabolic process GO:0042447 17 8 0,000 0,05115258 0,09577673 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,05115258 0,09570225 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,05115258 0,09562789 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,05115258 0,09555365 ! ATP catabolic process GO:0006200 11 8 0,000 0,05115258 0,09547952 ! blastocyst growth GO:0001832 19 8 0,000 0,05115258 0,0954055 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,05115258 0,0953316 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,05115258 0,09525782 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,05115258 0,09518414 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,05115258 0,09511059 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,05115258 0,09503714 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,05115258 0,09496381 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,05115258 0,09489059 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,05115258 0,09481749 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,05115258 0,09474449 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,05115258 0,09467161 GO:0006043|glucosamine catabolic process, ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,05115258 0,09459884 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,05115258 0,09452619 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,05115258 0,09445364 GO:0000076|DNA replication checkpoint, ! NAD biosynthetic process GO:0009435 13 8 0,000 0,05115258 0,09438121 ! regulation of actin filament length GO:0030832 105 56 1,000 0,05207096 0,09600209 ! skeletal muscle fiber development GO:0048741 111 56 1,000 0,05207096 0,09592858 ! regulation of DNA replication GO:0006275 101 56 1,000 0,05207096 0,09585519 ! positive regulation of organelle organization GO:0010638 100 56 1,000 0,05207096 0,0957819 ! muscle fiber development GO:0048747 112 57 1,000 0,05373817 0,09877314 ! lipid modification GO:0030258 97 57 1,000 0,05373817 0,09869774 ! regulation of intracellular transport GO:0032386 101 57 1,000 0,05373817 0,09862246 ! maintenance of location GO:0051235 118 57 1,000 0,05373817 0,09854729 ! regulation of cellular component size GO:0032535 109 59 1,000 0,05712858 0,10468496 ! cytokine-mediated signaling pathway GO:0019221 97 59 1,000 0,05712858 0,10460529 ! DNA catabolic process GO:0006308 86 59 1,000 0,05712858 0,10452575 ! axon extension GO:0048675 15 9 0,000 0,05736078 0,10487086 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,05736078 0,10479123 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,05736078 0,10471172 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,05736078 0,10463233 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,05736078 0,10455307 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,05736078 0,10447392 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,05736078 0,10439489 ! phosphate transport GO:0006817 19 9 0,000 0,05736078 0,10431598 ! reproductive behavior GO:0019098 19 9 0,000 0,05736078 0,1042372 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,05736078 0,10415853 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,05736078 0,10407997 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,05736078 0,10400154 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,05736078 0,10392323 ! GTP metabolic process GO:0046039 9 9 0,000 0,05736078 0,10384503 ! RNA methylation GO:0001510 15 9 0,000 0,05736078 0,10376695 ! elastic fiber assembly GO:0048251 15 9 0,000 0,05736078 0,10368899 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,05736078 0,10361115 ! artery development GO:0060840 24 9 0,000 0,05736078 0,10353342 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,05736078 0,10345581 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,05736078 0,10337831 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,05736078 0,10330093 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,05736078 0,10322367 ! chemosensory behavior GO:0007635 20 9 0,000 0,05736078 0,10314652 ! microtubule bundle formation GO:0001578 21 9 0,000 0,05736078 0,10306949 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,05736078 0,10299257 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,05736078 0,10291577 ! leukocyte degranulation GO:0043299 16 9 0,000 0,05736078 0,10283908 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,05736078 0,10276251 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,05736078 0,10268605 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,05736078 0,1026097 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,05736078 0,10253347 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,05736078 0,10245735 ! protein targeting to ER GO:0045047 22 9 0,000 0,05736078 0,10238134 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,05736078 0,10230545 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,05736078 0,10222966 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,05736078 0,10215399 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,05736078 0,10207844 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,05736078 0,10200299 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,05736078 0,10192766 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,05736078 0,10185243 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,05736078 0,10177732 ! mannose metabolic process GO:0006013 13 9 0,000 0,05736078 0,10170232 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,05736078 0,10162743 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,05736078 0,10155265 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,05736078 0,10147798 ! receptor clustering GO:0043113 18 9 0,000 0,05736078 0,10140341 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,05736078 0,10132896 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,05736078 0,10125462 ! ruffle organization GO:0031529 15 9 0,000 0,05736078 0,10118039 ! retinol metabolic process GO:0042572 18 9 0,000 0,05736078 0,10110626 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,05736078 0,10103224 ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,05736078 0,10095834 GO:0007351|tripartite regional subdivision, ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,05736078 0,10088454 GO:0030204|chondroitin sulfate metabolic process, ! oligodendrocyte development GO:0014003 10 9 0,000 0,05736078 0,10081084 ! segment specification GO:0007379 13 9 0,000 0,05736078 0,10073726 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,05736078 0,10066378 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,05736078 0,10059041 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,05736078 0,10051715 ! establishment of melanosome localization GO:0032401 14 9 0,000 0,05736078 0,10044399 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,05736078 0,10037094 ! erythrocyte development GO:0048821 15 9 0,000 0,05736078 0,100298 ! renal water homeostasis GO:0003091 14 9 0,000 0,05736078 0,10022516 ! postreplication repair GO:0006301 22 9 0,000 0,05736078 0,10015243 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,05736078 0,1000798 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,05736078 0,10000728 ! icosanoid secretion GO:0032309 15 9 0,000 0,05736078 0,09993486 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,05736078 0,09986255 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,05736078 0,09979034 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,05736078 0,09971824 ! regulation of cell division GO:0051302 15 9 0,000 0,05736078 0,09964624 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,05736078 0,09957435 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,05736078 0,09950256 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,05736078 0,09943087 ! sterol catabolic process GO:0016127 11 9 0,000 0,05736078 0,09935928 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,05736078 0,0992878 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,05736078 0,09921642 ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,05736078 0,09914515 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,05736078 0,09907397 ! musculoskeletal movement GO:0050881 14 9 0,000 0,05736078 0,0990029 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,05736078 0,09893193 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,05736078 0,09886106 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,05736078 0,0987903 ! purine base metabolic process GO:0006144 21 9 0,000 0,05736078 0,09871963 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,05736078 0,09864907 ! pigment granule transport GO:0051904 17 9 0,000 0,05736078 0,0985786 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,05736078 0,09850824 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,05736078 0,09843798 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,05736078 0,09836782 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,05736078 0,09829775 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,05736078 0,09822779 ! mitochondrion localization GO:0051646 15 9 0,000 0,05736078 0,09815793 ! DNA damage response, signal transduction GO:0042770 128 60 1,000 0,05885114 0,10063671 ! nucleoside metabolic process GO:0009116 81 60 1,000 0,05885114 0,10056523 ! kidney development GO:0001822 122 60 1,000 0,05885114 0,10049386 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,06352858 0,10840408 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,06352858 0,10832726 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,06352858 0,10825054 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,06352858 0,10817393 ! synapsis GO:0007129 13 10 0,000 0,06352858 0,10809742 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,06352858 0,10802103 ! N-glycan processing GO:0006491 20 10 0,000 0,06352858 0,10794474 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,06352858 0,10786857 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,06352858 0,10779249 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,06352858 0,10771653 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,06352858 0,10764067 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,06352858 0,10756492 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,06352858 0,10748928 ! androgen metabolic process GO:0008209 17 10 0,000 0,06352858 0,10741374 ! phospholipid efflux GO:0033700 16 10 0,000 0,06352858 0,10733831 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,06352858 0,10726299 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,06352858 0,10718777 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,06352858 0,10711265 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,06352858 0,10703765 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,06352858 0,10696274 ! endoderm development GO:0007492 16 10 0,000 0,06352858 0,10688794 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,06352858 0,10681325 ! arginine catabolic process GO:0006527 13 10 0,000 0,06352858 0,10673866 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,06352858 0,10666417 ! proline metabolic process GO:0006560 13 10 0,000 0,06352858 0,10658979 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,06352858 0,10651551 GO:0005978|glycogen biosynthetic process, ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,06352858 0,10644134 ! V(D)J recombination GO:0033151 28 10 0,000 0,06352858 0,10636726 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,06352858 0,10629329 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,06352858 0,10621943 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,06352858 0,10614566 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,06352858 0,106072 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,06352858 0,10599844 ! multicellular organism growth GO:0035264 18 10 0,000 0,06352858 0,10592499 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,06352858 0,10585163 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,06352858 0,10577838 ! epithelial cell development GO:0002064 20 10 0,000 0,06352858 0,10570523 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,06352858 0,10563218 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,06352858 0,10555922 ! macroautophagy GO:0016236 17 10 0,000 0,06352858 0,10548638 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,06352858 0,10541363 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,06352858 0,10534098 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,06352858 0,10526843 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,06352858 0,10519598 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 0,06352858 0,10512363 ! copper ion homeostasis GO:0055070 13 10 0,000 0,06352858 0,10505138 ! brain morphogenesis GO:0048854 23 10 0,000 0,06352858 0,10497923 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,06352858 0,10490718 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,06352858 0,10483522 ! blastoderm segmentation GO:0007350 18 10 0,000 0,06352858 0,10476337 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,06352858 0,10469161 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,06352858 0,10461996 ! melanosome localization GO:0032400 16 10 0,000 0,06352858 0,1045484 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,06352858 0,10447694 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,06352858 0,10440557 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,06352858 0,10433431 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,06352858 0,10426314 ! mRNA cleavage GO:0006379 17 10 0,000 0,06352858 0,10419206 ! protein sumoylation GO:0016925 15 10 0,000 0,06352858 0,10412109 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,06352858 0,10405021 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,06352858 0,10397943 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,06352858 0,10390874 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,06352858 0,10383815 ! salivary gland development GO:0007431 27 10 0,000 0,06352858 0,10376766 ! prophase GO:0051324 15 10 0,000 0,06352858 0,10369726 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,06352858 0,10362695 ! apical protein localization GO:0045176 15 10 0,000 0,06352858 0,10355675 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,06352858 0,10348663 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,06352858 0,10341662 ! midbrain development GO:0030901 13 10 0,000 0,06352858 0,10334669 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,06352858 0,10327686 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,06352858 0,10320713 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,06352858 0,10313749 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,06352858 0,10306794 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,06352858 0,10299849 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,06352858 0,10292913 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,06352858 0,10285986 ! detection of calcium ion GO:0005513 23 10 0,000 0,06352858 0,10279069 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,06352858 0,10272161 ! blastocyst formation GO:0001825 17 10 0,000 0,06352858 0,10265262 ! cerebellar cortex development GO:0021695 15 10 0,000 0,06352858 0,10258373 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,06352858 0,10251493 ! activation of innate immune response GO:0002218 12 10 0,000 0,06352858 0,10244622 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,06352858 0,1023776 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,06352858 0,10230907 ! establishment of cell polarity GO:0030010 16 10 0,000 0,06352858 0,10224064 ! detection of external stimulus GO:0009581 91 63 1,000 0,06412461 0,10313089 ! steroid hormone receptor signaling pathway GO:0030518 129 63 1,000 0,06412461 0,103062 ! multicellular organism reproduction GO:0032504 111 64 1,000 0,06591669 0,10587153 GO:0048609|reproductive process in a multicellular organism, ! regulation of cytokine biosynthetic process GO:0042035 95 65 1,000 0,0677254 0,10870401 ! embryonic limb morphogenesis GO:0030326 125 65 1,000 0,0677254 0,10863154 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 1,000 0,0677254 0,10855916 ! actin filament organization GO:0007015 148 66 1,000 0,06955045 0,11141037 ! secondary metabolic process GO:0019748 116 66 1,000 0,06955045 0,11133625 ! respiratory burst GO:0045730 17 11 0,000 0,06965622 0,11143142 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,06965622 0,11135738 ! neuron fate specification GO:0048665 17 11 0,000 0,06965622 0,11128344 ! telencephalon cell migration GO:0022029 20 11 0,000 0,06965622 0,1112096 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,06965622 0,11113585 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,06965622 0,1110622 ! thyroid gland development GO:0030878 26 11 0,000 0,06965622 0,11098865 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,06965622 0,1109152 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,06965622 0,11084184 ! response to pain GO:0048265 24 11 0,000 0,06965622 0,11076858 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,06965622 0,11069542 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,06965622 0,11062235 GO:0010812|negative regulation of cell-substrate adhesion, ! bone resorption GO:0045453 16 11 0,000 0,06965622 0,11054938 ! ventral spinal cord development GO:0021517 21 11 0,000 0,06965622 0,11047651 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,06965622 0,11040373 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,06965622 0,11033105 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,06965622 0,11025846 ! melanocyte differentiation GO:0030318 21 11 0,000 0,06965622 0,11018597 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,06965622 0,11011357 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,06965622 0,11004127 GO:0010833|telomere maintenance via telomere lengthening, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,06965622 0,10996907 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,06965622 0,10989696 ! lipid digestion GO:0044241 18 11 0,000 0,06965622 0,10982494 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,06965622 0,10975302 ! UV protection GO:0009650 19 11 0,000 0,06965622 0,10968119 ! adult heart development GO:0007512 14 11 0,000 0,06965622 0,10960946 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,06965622 0,10953782 ! temperature homeostasis GO:0001659 17 11 0,000 0,06965622 0,10946627 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,06965622 0,10939482 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,06965622 0,10932346 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,06965622 0,10925219 ! regulation of organ growth GO:0046620 13 11 0,000 0,06965622 0,10918102 ! pigment granule localization GO:0051875 20 11 0,000 0,06965622 0,10910994 ! vasoconstriction GO:0042310 18 11 0,000 0,06965622 0,10903895 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,06965622 0,10896805 ! embryonic axis specification GO:0000578 18 11 0,000 0,06965622 0,10889725 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,06965622 0,10882653 ! snRNA metabolic process GO:0016073 24 11 0,000 0,06965622 0,10875591 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,06965622 0,10868538 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,06965622 0,10861495 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,06965622 0,1085446 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,06965622 0,10847434 ! zymogen activation GO:0031638 15 11 0,000 0,06965622 0,10840418 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,06965622 0,1083341 ! nucleosome positioning GO:0016584 15 11 0,000 0,06965622 0,10826412 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,06965622 0,10819423 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,06965622 0,10812443 ! acid secretion GO:0046717 18 11 0,000 0,06965622 0,10805471 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,06965622 0,10798509 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,06965622 0,10791556 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,06965622 0,10784611 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,06965622 0,10777676 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,06965622 0,10770749 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! cholesterol efflux GO:0033344 19 11 0,000 0,06965622 0,10763832 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,06965622 0,10756923 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,06965622 0,10750023 ! germ cell migration GO:0008354 25 11 0,000 0,06965622 0,10743132 ! embryonic gut development GO:0048566 15 11 0,000 0,06965622 0,1073625 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,06965622 0,10729376 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,06965622 0,10722512 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,06965622 0,10715656 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,06965622 0,10708809 ! defense response to fungus GO:0050832 13 11 0,000 0,06965622 0,10701971 ! developmental induction GO:0031128 19 11 0,000 0,06965622 0,10695141 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,06965622 0,1068832 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,06965622 0,10681508 ! sequestering of metal ion GO:0051238 14 11 0,000 0,06965622 0,10674704 ! lamellipodium assembly GO:0030032 20 11 0,000 0,06965622 0,1066791 ! regulation of synapse organization GO:0050807 17 11 0,000 0,06965622 0,10661123 ! regulation of cellular response to stress GO:0080135 128 67 1,000 0,07139155 0,10919776 ! homeostasis of number of cells GO:0048872 114 67 1,000 0,07139155 0,10912838 ! hexose catabolic process GO:0019320 104 67 1,000 0,07139155 0,10905909 ! adaptive immune response GO:0002250 119 67 1,000 0,07139155 0,10898989 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 1,000 0,07139155 0,10892078 ! amino acid transport GO:0006865 125 68 1,000 0,07324842 0,11168296 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 1,000 0,07324842 0,11161223 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 1,000 0,07324842 0,11154159 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 1,000 0,07512078 0,11432043 ! coenzyme biosynthetic process GO:0009108 102 69 1,000 0,07512078 0,11424816 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,07574397 0,11512317 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,07574397 0,11505049 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,07574397 0,11497791 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,07574397 0,11490541 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,07574397 0,11483301 ! cartilage condensation GO:0001502 20 12 0,000 0,07574397 0,11476069 ! mating GO:0007618 17 12 0,000 0,07574397 0,11468847 ! protein complex disassembly GO:0043241 27 12 0,000 0,07574397 0,11461634 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,07574397 0,1145443 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 0,07574397 0,11447235 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,07574397 0,11440049 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,07574397 0,11432872 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,07574397 0,11425704 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,07574397 0,11418545 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,07574397 0,11411395 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,07574397 0,11404254 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,07574397 0,11397122 ! drug transport GO:0015893 16 12 0,000 0,07574397 0,11389999 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,07574397 0,11382884 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,07574397 0,11375779 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,07574397 0,11368683 ! polyamine metabolic process GO:0006595 17 12 0,000 0,07574397 0,11361595 ! mitotic spindle organization GO:0007052 21 12 0,000 0,07574397 0,11354516 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,07574397 0,11347446 ! forebrain cell migration GO:0021885 21 12 0,000 0,07574397 0,11340385 ! asymmetric protein localization GO:0008105 20 12 0,000 0,07574397 0,11333332 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,07574397 0,11326288 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,07574397 0,11319253 ! monoamine transport GO:0015844 18 12 0,000 0,07574397 0,11312227 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,07574397 0,1130521 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,07574397 0,11298201 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,07574397 0,11291201 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,07574397 0,11284209 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,07574397 0,11277227 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,07574397 0,11270252 ! protein homotetramerization GO:0051289 21 12 0,000 0,07574397 0,11263287 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,07574397 0,1125633 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,07574397 0,11249382 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,07574397 0,11242442 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,07574397 0,11235511 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,07574397 0,11228588 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,07574397 0,11221674 ! cranial nerve development GO:0021545 20 12 0,000 0,07574397 0,11214768 ! fucose catabolic process GO:0019317 22 12 0,000 0,07574397 0,11207871 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,07574397 0,11200982 ! histone methylation GO:0016571 26 12 0,000 0,07574397 0,11194102 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,07574397 0,1118723 ! autonomic nervous system development GO:0048483 24 12 0,000 0,07574397 0,11180367 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,07574397 0,11173512 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,07574397 0,11166665 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,07574397 0,11159827 ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,07574397 0,11152998 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,07574397 0,11146176 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,07574397 0,11139363 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,07574397 0,11132558 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,07574397 0,11125762 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,07574397 0,11118974 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,07574397 0,11112194 ! appendage morphogenesis GO:0035107 135 70 1,000 0,07700834 0,11290802 GO:0035108|limb morphogenesis, ! appendage development GO:0048736 136 71 1,000 0,07891083 0,11562695 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 1,000 0,07891083 0,11555658 ! B cell activation GO:0042113 160 71 1,000 0,07891083 0,11548629 ! regulation of immune effector process GO:0002697 137 71 1,000 0,07891083 0,11541608 ! phosphoinositide metabolic process GO:0030384 128 72 1,000 0,08082797 0,1181483 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 1,000 0,08082797 0,11807657 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 1,000 0,08082797 0,11800492 ! cGMP metabolic process GO:0046068 18 13 0,000 0,08179208 0,11934005 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,08179208 0,11926772 ! regulation of chemokine production GO:0032642 18 13 0,000 0,08179208 0,11919548 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,08179208 0,11912333 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,08179208 0,11905126 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,08179208 0,11897929 ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,08179208 0,1189074 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,08179208 0,11883559 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,08179208 0,11876387 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,08179208 0,11869224 ! endocrine pancreas development GO:0031018 22 13 0,000 0,08179208 0,1186207 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,08179208 0,11854924 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,08179208 0,11847787 ! methionine metabolic process GO:0006555 27 13 0,000 0,08179208 0,11840658 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,08179208 0,11833538 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,08179208 0,11826427 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,08179208 0,11819324 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cell-cell junction assembly GO:0007043 27 13 0,000 0,08179208 0,11812229 ! response to X-ray GO:0010165 25 13 0,000 0,08179208 0,11805143 ! cytokine metabolic process GO:0042107 22 13 0,000 0,08179208 0,11798066 ! exocrine system development GO:0035272 32 13 0,000 0,08179208 0,11790997 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,08179208 0,11783937 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,08179208 0,11776885 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,08179208 0,11769841 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,08179208 0,11762806 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,08179208 0,11755779 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,08179208 0,11748761 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,08179208 0,11741751 ! regulation of cellular pH GO:0030641 22 13 0,000 0,08179208 0,11734749 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,08179208 0,11727756 ! ribosome assembly GO:0042255 17 13 0,000 0,08179208 0,11720771 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,08179208 0,11713794 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,08179208 0,11706826 ! chromatin silencing GO:0006342 26 13 0,000 0,08179208 0,11699866 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,08179208 0,11692914 ! regulation of epidermis development GO:0045682 19 13 0,000 0,08179208 0,1168597 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,08179208 0,11679035 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,08179208 0,11672108 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,08179208 0,11665189 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,08179208 0,11658278 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,08179208 0,11651376 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,08179208 0,11644482 ! embryonic placenta development GO:0001892 23 13 0,000 0,08179208 0,11637596 ! insulin secretion GO:0030073 23 13 0,000 0,08179208 0,11630718 ! actin filament polymerization GO:0030041 24 13 0,000 0,08179208 0,11623848 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,08179208 0,11616986 ! acrosome reaction GO:0007340 18 13 0,000 0,08179208 0,11610132 ! regulation of transcription factor activity GO:0051090 126 74 1,000 0,08470515 0,12016544 GO:0090046|regulation of transcription regulator activity, ! regulation of actin cytoskeleton organization GO:0032956 149 74 1,000 0,08470515 0,12009463 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 1,000 0,08666464 0,12280043 ! rhythmic process GO:0048511 128 75 1,000 0,08666464 0,12272815 ! lactation GO:0007595 26 14 0,000 0,08780081 0,12426397 ! reproductive cellular process GO:0048610 20 14 0,000 0,08780081 0,12419092 ! tRNA modification GO:0006400 20 14 0,000 0,08780081 0,12411795 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,08780081 0,12404507 ! water transport GO:0006833 21 14 0,000 0,08780081 0,12397228 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,08780081 0,12389956 ! non-recombinational repair GO:0000726 25 14 0,000 0,08780081 0,12382694 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,08780081 0,1237544 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,08780081 0,12368194 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,08780081 0,12360957 ! RNA polyadenylation GO:0043631 30 14 0,000 0,08780081 0,12353728 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,08780081 0,12346508 ! palate development GO:0060021 31 14 0,000 0,08780081 0,12339297 ! regulated secretory pathway GO:0045055 23 14 0,000 0,08780081 0,12332093 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,08780081 0,12324898 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,08780081 0,12317712 ! arginine metabolic process GO:0006525 17 14 0,000 0,08780081 0,12310534 ! regulation of heart rate GO:0002027 24 14 0,000 0,08780081 0,12303364 ! organic alcohol transport GO:0015850 29 14 0,000 0,08780081 0,12296202 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,08780081 0,12289049 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,08780081 0,12281904 ! embryo implantation GO:0007566 30 14 0,000 0,08780081 0,12274768 ! neutral amino acid transport GO:0015804 26 14 0,000 0,08780081 0,1226764 ! L-amino acid transport GO:0015807 30 14 0,000 0,08780081 0,1226052 ! bone mineralization GO:0030282 17 14 0,000 0,08780081 0,12253408 ! stem cell development GO:0048864 43 14 0,000 0,08780081 0,12246305 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,08780081 0,1223921 ! cerebellum development GO:0021549 21 14 0,000 0,08780081 0,12232123 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,08780081 0,12225044 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,08780081 0,12217973 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,08780081 0,12210911 ! cofactor transport GO:0051181 26 14 0,000 0,08780081 0,12203857 ! NADP metabolic process GO:0006739 24 14 0,000 0,08780081 0,1219681 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,08780081 0,12189772 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,08780081 0,12182743 ! intestinal absorption GO:0050892 25 14 0,000 0,08780081 0,12175721 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,08780081 0,12168707 ! oxygen transport GO:0015671 21 14 0,000 0,08780081 0,12161702 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,08780081 0,12154704 ! male genitalia development GO:0030539 24 14 0,000 0,08780081 0,12147715 ! regulation of axon extension GO:0030516 37 14 0,000 0,08780081 0,12140733 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,08780081 0,1213376 ! cytosolic calcium ion homeostasis GO:0051480 135 76 1,000 0,08863773 0,12242387 ! monosaccharide catabolic process GO:0046365 115 76 1,000 0,08863773 0,12235363 ! regulation of actin filament-based process GO:0032970 152 77 1,000 0,09062414 0,1250239 ! positive regulation of ligase activity GO:0051351 124 77 1,000 0,09062414 0,12495226 ! blood coagulation GO:0007596 146 78 1,000 0,09262363 0,127636 GO:0050817|coagulation, ! response to steroid hormone stimulus GO:0048545 137 78 1,000 0,09262363 0,12756294 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,09377043 0,12906845 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,09377043 0,12899465 ! superoxide anion generation GO:0042554 20 15 0,000 0,09377043 0,12892094 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,09377043 0,12884731 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,09377043 0,12877377 ! copper ion transport GO:0006825 20 15 0,000 0,09377043 0,12870031 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,09377043 0,12862694 ! sulfate transport GO:0008272 23 15 0,000 0,09377043 0,12855364 ! response to cAMP GO:0051591 22 15 0,000 0,09377043 0,12848044 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,09377043 0,12840731 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,09377043 0,12833427 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,09377043 0,12826131 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,09377043 0,12818843 ! response to hexose stimulus GO:0009746 22 15 0,000 0,09377043 0,12811564 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,09377043 0,12804293 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,09377043 0,1279703 ! vesicle coating GO:0006901 33 15 0,000 0,09377043 0,12789776 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,09377043 0,12782529 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,09377043 0,12775291 ! regulation of exocytosis GO:0017157 22 15 0,000 0,09377043 0,12768061 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,09377043 0,1276084 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,09377043 0,12753626 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,09377043 0,12746421 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,09377043 0,12739223 ! histone deacetylation GO:0016575 20 15 0,000 0,09377043 0,12732034 ! mRNA splice site selection GO:0006376 38 15 0,000 0,09377043 0,12724853 ! tissue regeneration GO:0042246 26 15 0,000 0,09377043 0,1271768 ! water homeostasis GO:0030104 27 15 0,000 0,09377043 0,12710515 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,09377043 0,12703358 ! muscle maintenance GO:0046716 26 15 0,000 0,09377043 0,1269621 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,09377043 0,12689069 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,09377043 0,12681936 ! heme biosynthetic process GO:0006783 29 15 0,000 0,09377043 0,12674811 ! cell killing GO:0001906 29 15 0,000 0,09377043 0,12667695 ! detection of bacterium GO:0016045 18 15 0,000 0,09377043 0,12660586 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,09377043 0,12653485 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,09377043 0,12646393 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,09377043 0,12639308 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,09377043 0,12632231 ! peptide hormone processing GO:0016486 23 15 0,000 0,09377043 0,12625162 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 1,000 0,09463593 0,12734567 ! response to metal ion GO:0010038 140 80 1,000 0,09666081 0,12999771 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,09970117 0,13401174 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,09970117 0,13393691 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,09970117 0,13386217 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,09970117 0,13378751 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,09970117 0,13371294 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,09970117 0,13363845 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,09970117 0,13356404 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,09970117 0,13348971 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,09970117 0,13341547 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,09970117 0,13334131 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,09970117 0,13326723 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,09970117 0,13319323 ! protein polyubiquitination GO:0000209 34 16 0,000 0,09970117 0,13311932 ! glutamate metabolic process GO:0006536 22 16 0,000 0,09970117 0,13304549 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,09970117 0,13297174 ! response to osmotic stress GO:0006970 25 16 0,000 0,09970117 0,13289807 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,09970117 0,13282448 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,09970117 0,13275097 ! fructose metabolic process GO:0006000 25 16 0,000 0,09970117 0,13267755 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,09970117 0,13260421 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,09970117 0,13253095 ! intermediate filament-based process GO:0045103 32 16 0,000 0,09970117 0,13245776 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,09970117 0,13238466 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,09970117 0,13231164 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,09970117 0,13223871 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 0,09970117 0,13216585 ! DNA replication initiation GO:0006270 27 16 0,000 0,09970117 0,13209307 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,09970117 0,13202037 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,09970117 0,13194775 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,09970117 0,13187521 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,09970117 0,13180275 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,09970117 0,13173037 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,09970117 0,13165807 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,09970117 0,13158585 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,09970117 0,13151371 ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,09970117 0,13144165 ! hemostasis GO:0007599 158 84 1,000 0,10488105 0,13819486 ! regulation of ligase activity GO:0051340 142 84 1,000 0,10488105 0,13811922 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,10559329 0,13898111 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,10559329 0,13890512 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,10559329 0,13882922 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,10559329 0,13875339 ! signal complex assembly GO:0007172 41 17 0,000 0,10559329 0,13867766 ! endothelial cell migration GO:0043542 28 17 0,000 0,10559329 0,138602 ! inositol metabolic process GO:0006020 28 17 0,000 0,10559329 0,13852643 ! gene silencing by RNA GO:0031047 36 17 0,000 0,10559329 0,13845094 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,10559329 0,13837553 ! glial cell development GO:0021782 27 17 0,000 0,10559329 0,1383002 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,10559329 0,13822495 ! adult walking behavior GO:0007628 33 17 0,000 0,10559329 0,13814979 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,10559329 0,13807471 ! heart looping GO:0001947 30 17 0,000 0,10559329 0,13799971 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,10559329 0,13792479 ! myoblast differentiation GO:0045445 45 17 0,000 0,10559329 0,13784995 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,10559329 0,1377752 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,10559329 0,13770052 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,10559329 0,13762593 ! glycine metabolic process GO:0006544 28 17 0,000 0,10559329 0,13755142 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,10559329 0,13747698 ! NAD metabolic process GO:0019674 29 17 0,000 0,10559329 0,13740263 ! membrane budding GO:0006900 37 17 0,000 0,10559329 0,13732836 ! DNA integration GO:0015074 29 17 0,000 0,10559329 0,13725417 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,10559329 0,13718006 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,10559329 0,13710603 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,10559329 0,13703207 ! genitalia development GO:0048806 30 17 0,000 0,10559329 0,1369582 ! neural crest cell migration GO:0001755 37 17 0,000 0,10559329 0,13688441 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,10559329 0,1368107 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,10559329 0,13673706 ! steroid catabolic process GO:0006706 31 17 0,000 0,10559329 0,13666351 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,10559329 0,13659004 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,10559329 0,13651664 ! gas transport GO:0015669 25 17 0,000 0,10559329 0,13644332 ! organic cation transport GO:0015695 31 17 0,000 0,10559329 0,13637008 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,10559329 0,13629692 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,10559329 0,13622384 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,10559329 0,13615084 ! response to inorganic substance GO:0010035 153 86 1,000 0,10906025 0,14054578 ! alcohol catabolic process GO:0046164 130 86 1,000 0,10906025 0,14047054 ! amine transport GO:0015837 155 86 1,000 0,10906025 0,14039538 ! regulation of protein transport GO:0051223 154 87 1,000 0,11116629 0,14303 GO:0070201|regulation of establishment of protein localization, ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,11144705 0,1433146 ! neuron maturation GO:0042551 42 18 0,000 0,11144705 0,14323804 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,11144705 0,14316156 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,11144705 0,14308517 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,11144705 0,14300886 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,11144705 0,14293263 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,11144705 0,14285648 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,11144705 0,14278041 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,11144705 0,14270442 ! patterning of blood vessels GO:0001569 39 18 0,000 0,11144705 0,14262851 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,11144705 0,14255269 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,11144705 0,14247694 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,11144705 0,14240128 ! glutamine metabolic process GO:0006541 29 18 0,000 0,11144705 0,14232569 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,11144705 0,14225019 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,11144705 0,14217477 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,11144705 0,14209942 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,11144705 0,14202416 ! vitamin transport GO:0051180 27 18 0,000 0,11144705 0,14194897 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,11144705 0,14187387 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,11144705 0,14179884 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,11144705 0,14172389 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,11144705 0,14164903 ! nerve development GO:0021675 28 18 0,000 0,11144705 0,14157424 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,11144705 0,14149953 ! cellular respiration GO:0045333 135 88 1,000 0,11328299 0,14375468 ! regulation of DNA binding GO:0051101 155 88 1,000 0,11328299 0,1436789 ! regulation of cell morphogenesis GO:0022604 215 89 1,000 0,11541011 0,14629964 ! protein secretion GO:0009306 39 19 0,000 0,11726269 0,14856979 ! positive regulation of translation GO:0045727 30 19 0,000 0,11726269 0,1484916 ! negative regulation of defense response GO:0031348 25 19 0,000 0,11726269 0,14841349 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,11726269 0,14833546 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,11726269 0,14825751 ! skin development GO:0043588 36 19 0,000 0,11726269 0,14817964 ! bile acid metabolic process GO:0008206 29 19 0,000 0,11726269 0,14810186 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,11726269 0,14802415 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,11726269 0,14794653 ! cerebral cortex development GO:0021987 36 19 0,000 0,11726269 0,14786899 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,11726269 0,14779153 GO:0030968|endoplasmic reticulum unfolded protein response, ! heme metabolic process GO:0042168 36 19 0,000 0,11726269 0,14771416 ! actin filament bundle formation GO:0051017 42 19 0,000 0,11726269 0,14763686 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,11726269 0,14755964 ! peptide cross-linking GO:0018149 37 19 0,000 0,11726269 0,14748251 ! protein export from nucleus GO:0006611 36 19 0,000 0,11726269 0,14740545 ! heart process GO:0003015 30 19 0,000 0,11726269 0,14732848 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,11726269 0,14725158 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,11726269 0,14717477 ! G1 phase GO:0051318 40 19 0,000 0,11726269 0,14709804 ! cell-cell junction organization GO:0045216 35 19 0,000 0,11726269 0,14702138 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,11726269 0,14694481 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,11726269 0,14686832 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,11726269 0,1467919 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,11726269 0,14671557 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,11726269 0,14663931 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,11726269 0,14656314 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,11726269 0,14648704 ! cilium assembly GO:0042384 37 19 0,000 0,11726269 0,14641102 ! peptide hormone secretion GO:0030072 31 19 0,000 0,11726269 0,14633508 ! regulation of cell cycle process GO:0010564 149 90 1,000 0,11754743 0,14661437 ! response to protein stimulus GO:0051789 149 91 1,000 0,11969474 0,1492153 ! cofactor biosynthetic process GO:0051188 139 91 1,000 0,11969474 0,14913803 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,12304046 0,1532274 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,12304046 0,15314814 ! positive regulation of ossification GO:0045778 47 20 0,000 0,12304046 0,15306895 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,12304046 0,15298984 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,12304046 0,15291082 ! cAMP metabolic process GO:0046058 36 20 0,000 0,12304046 0,15283188 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,12304046 0,15275302 ! retinoid metabolic process GO:0001523 32 20 0,000 0,12304046 0,15267424 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,12304046 0,15259554 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,12304046 0,15251692 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,12304046 0,15243839 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,12304046 0,15235993 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 0,000 0,12304046 0,15228156 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,12304046 0,15220326 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,12304046 0,15212505 ! body fluid secretion GO:0007589 31 20 0,000 0,12304046 0,15204692 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,12304046 0,15196886 ! peptide secretion GO:0002790 35 20 0,000 0,12304046 0,15189089 ! stem cell differentiation GO:0048863 53 20 0,000 0,12304046 0,151813 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,12304046 0,15173518 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,12304046 0,15165745 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,12304046 0,1515798 GO:0006626|protein targeting to mitochondrion, ! detection of chemical stimulus GO:0009593 37 20 0,000 0,12304046 0,15150222 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,12304046 0,15142473 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,12304046 0,15134731 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,12304046 0,15126998 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,12304046 0,15119272 ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,12304046 0,15111554 ! actin filament-based movement GO:0030048 43 20 0,000 0,12304046 0,15103844 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,12304046 0,15096142 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,12304046 0,15088448 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,12304046 0,15080761 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 1,000 0,1240184 0,15192885 GO:0010498|proteasomal protein catabolic process, ! biogenic amine metabolic process GO:0006576 155 94 1,000 0,12619433 0,1545158 ! female pregnancy GO:0007565 164 94 1,000 0,12619433 0,15443721 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,1287806 0,15752218 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,1287806 0,15744214 ! hormone secretion GO:0046879 38 21 0,000 0,1287806 0,15736218 ! glycerol metabolic process GO:0006071 34 21 0,000 0,1287806 0,1572823 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,1287806 0,1572025 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,1287806 0,15712278 ! axis specification GO:0009798 38 21 0,000 0,1287806 0,15704314 ! smooth muscle contraction GO:0006939 46 21 0,000 0,1287806 0,15696359 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,1287806 0,15688411 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,1287806 0,15680472 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,1287806 0,1567254 ! cytolysis GO:0019835 24 21 0,000 0,1287806 0,15664617 ! vasodilation GO:0042311 39 21 0,000 0,1287806 0,15656702 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,1287806 0,15648794 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,1287806 0,15640895 ! DNA modification GO:0006304 34 21 0,000 0,1287806 0,15633003 ! collagen fibril organization GO:0030199 59 21 0,000 0,1287806 0,1562512 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,1287806 0,15617244 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,1287806 0,15609377 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,1287806 0,15601517 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,1287806 0,15593665 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,1287806 0,15585821 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,1287806 0,15577985 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,1287806 0,15570157 ! collagen catabolic process GO:0030574 28 21 0,000 0,1287806 0,15562337 ! sperm-egg recognition GO:0035036 21 21 0,000 0,1287806 0,15554524 ! positive regulation of immune response GO:0050778 156 96 1,000 0,13057331 0,1576314 ! detection of stimulus GO:0051606 151 96 1,000 0,13057331 0,15755235 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,13448336 0,16218895 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,13448336 0,1621077 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,13448336 0,16202652 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,13448336 0,16194543 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,13448336 0,16186441 GO:0034105|positive regulation of tissue remodeling, ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,13448336 0,16178348 ! keratinization GO:0031424 28 22 0,000 0,13448336 0,16170263 ! sensory perception of taste GO:0050909 28 22 0,000 0,13448336 0,16162186 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,13448336 0,16154117 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,13448336 0,16146056 ! vacuolar transport GO:0007034 36 22 0,000 0,13448336 0,16138003 ! lysosome organization GO:0007040 41 22 0,000 0,13448336 0,16129958 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,13448336 0,16121921 ! fucose metabolic process GO:0006004 39 22 0,000 0,13448336 0,16113893 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,13448336 0,16105872 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,13448336 0,16097859 GO:0060415|muscle tissue morphogenesis, ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,13448336 0,16089854 ! sarcomere organization GO:0045214 30 22 0,000 0,13448336 0,16081857 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,13448336 0,16073868 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,13448336 0,16065887 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,13448336 0,16057914 ! protein stabilization GO:0050821 39 22 0,000 0,13448336 0,16049949 ! cell cycle arrest GO:0007050 213 100 1,000 0,13943396 0,16632529 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,14014898 0,16709536 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,14014898 0,1670126 ! gluconeogenesis GO:0006094 33 23 0,000 0,14014898 0,16692992 ! viral genome replication GO:0019079 41 23 0,000 0,14014898 0,16684732 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,14014898 0,16676481 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,14014898 0,16668237 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,14014898 0,16660002 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,14014898 0,16651775 GO:0006044|N-acetylglucosamine metabolic process, ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,14014898 0,16643556 ! peroxisome organization GO:0007031 37 23 0,000 0,14014898 0,16635345 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,14014898 0,16627142 ! vesicle targeting GO:0006903 43 23 0,000 0,14014898 0,16618947 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,14014898 0,16610761 GO:0051693|actin filament capping, ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,14014898 0,16602582 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,14014898 0,16594411 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,14014898 0,16586249 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,14014898 0,16578094 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,14014898 0,16569948 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,14014898 0,16561809 ! fatty acid transport GO:0015908 44 23 0,000 0,14014898 0,16553679 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,14014898 0,16545556 ! hormone transport GO:0009914 40 23 0,000 0,14014898 0,16537442 ! cell-cell recognition GO:0009988 25 23 0,000 0,14014898 0,16529335 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,14014898 0,16521237 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,14014898 0,16513146 ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,14014898 0,16505063 ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,1457777 0,17159547 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,1457777 0,17151156 GO:0016444|somatic cell DNA recombination, ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,1457777 0,17142773 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,1457777 0,17134398 ! spinal cord development GO:0021510 47 24 0,000 0,1457777 0,17126032 ! vacuole organization GO:0007033 43 24 0,000 0,1457777 0,17117674 ! digestive system process GO:0022600 39 24 0,000 0,1457777 0,17109324 ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,1457777 0,17100982 ! pentose metabolic process GO:0019321 35 24 0,000 0,1457777 0,17092648 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,1457777 0,17084322 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,1457777 0,17076005 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,1457777 0,17067695 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,1457777 0,17059394 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,1457777 0,170511 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,1457777 0,17042815 ! regulation of amine transport GO:0051952 40 24 0,000 0,1457777 0,17034538 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,15136975 0,17679399 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,15136975 0,17670821 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,15136975 0,17662252 ! phototransduction GO:0007602 33 25 0,000 0,15136975 0,1765369 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,15136975 0,17645137 GO:0006479|protein amino acid methylation, ! sperm motility GO:0030317 31 25 0,000 0,15136975 0,17636592 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,15136975 0,17628056 ! receptor metabolic process GO:0043112 46 25 0,000 0,15136975 0,17619527 ! chromosome condensation GO:0030261 45 25 0,000 0,15136975 0,17611007 ! response to starvation GO:0042594 42 25 0,000 0,15136975 0,17602495 ! neural crest cell development GO:0014032 54 25 0,000 0,15136975 0,17593992 GO:0014033|neural crest cell differentiation, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,15136975 0,17585496 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,15136975 0,17577009 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,15136975 0,1756853 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,15136975 0,17560059 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,15136975 0,17551596 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,15136975 0,17543142 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,15136975 0,17534696 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,15136975 0,17526257 ! telomere organization GO:0032200 43 25 0,000 0,15136975 0,17517827 GO:0000723|telomere maintenance, ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,15692539 0,18152042 ! embryonic pattern specification GO:0009880 44 26 0,000 0,15692539 0,1814332 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,15692539 0,18134605 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,15692539 0,18125899 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,15692539 0,18117202 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,15692539 0,18108512 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,15692539 0,18099831 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,15692539 0,18091159 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,15692539 0,18082494 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,15692539 0,18073838 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,15692539 0,18065191 GO:0051297|centrosome organization, ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,15692539 0,18056551 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,15692539 0,1804792 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,15692539 0,18039297 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,15692539 0,18030682 GO:0045840|positive regulation of mitosis, ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,15692539 0,18022076 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,15692539 0,18013477 ! blastocyst development GO:0001824 49 26 0,000 0,15692539 0,18004887 ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,15692539 0,17996305 ! iron ion transport GO:0006826 59 27 0,000 0,16244484 0,18620404 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,16244484 0,18611537 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,16244484 0,18602678 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,16244484 0,18593828 ! fat cell differentiation GO:0045444 50 27 0,000 0,16244484 0,18584987 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,16244484 0,18576154 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,16244484 0,18567329 ! autophagy GO:0006914 41 27 0,000 0,16244484 0,18558513 ! base-excision repair GO:0006284 41 27 0,000 0,16244484 0,18549705 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,16244484 0,18540905 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,16244484 0,18532114 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,16244484 0,18523331 ! glutathione metabolic process GO:0006749 39 27 0,000 0,16244484 0,18514556 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,16244484 0,1850579 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,16244484 0,18497031 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,16792833 0,19112373 ! circadian rhythm GO:0007623 50 28 0,000 0,16792833 0,19103336 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,16792833 0,19094308 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,16792833 0,19085289 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,16792833 0,19076278 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,16792833 0,19067275 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,16792833 0,19058281 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,16792833 0,19049296 ! lipid oxidation GO:0034440 43 28 0,000 0,16792833 0,19040319 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,16792833 0,1903135 ! translational initiation GO:0006413 65 29 0,000 0,17337611 0,19639497 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,17337611 0,19630255 ! regulation of pH GO:0006885 43 29 0,000 0,17337611 0,19621021 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,17337611 0,19611797 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,17337611 0,1960258 ! complement activation, classical pathway GO:0006958 48 29 0,000 0,17337611 0,19593373 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,17337611 0,19584174 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,17337611 0,19574984 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,17337611 0,19565803 ! detection of light stimulus GO:0009583 38 29 0,000 0,17337611 0,1955663 ! zinc ion transport GO:0006829 45 30 0,000 0,17878839 0,20157679 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,17878839 0,20148238 ! regulation of innate immune response GO:0045088 51 30 0,000 0,17878839 0,20138805 ! acute-phase response GO:0006953 49 30 0,000 0,17878839 0,20129381 ! myofibril assembly GO:0030239 47 30 0,000 0,17878839 0,20119966 GO:0055002|striated muscle cell development, ! determination of left/right symmetry GO:0007368 47 30 0,000 0,17878839 0,2011056 ! phospholipid transport GO:0015914 51 30 0,000 0,17878839 0,20101162 ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,17878839 0,20091774 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 48 30 0,000 0,17878839 0,20082394 ! eye morphogenesis GO:0048592 60 30 0,000 0,17878839 0,20073023 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,18416542 0,20667071 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,18416542 0,20657436 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,18416542 0,2064781 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,18416542 0,20638193 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,18416542 0,20628585 ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,18416542 0,20618986 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,18416542 0,20609396 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,18416542 0,20599814 ! peptide transport GO:0015833 55 31 0,000 0,18416542 0,20590242 ! iron ion homeostasis GO:0055072 54 31 0,000 0,18416542 0,20580679 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,18416542 0,20571124 ! mesoderm formation GO:0001707 69 31 0,000 0,18416542 0,20561578 ! natural killer cell activation GO:0030101 45 31 0,000 0,18416542 0,20552041 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,18416542 0,20542513 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,18416542 0,20532994 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,18416542 0,20523483 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,18950742 0,21109021 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,18950742 0,21099253 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,18950742 0,21089494 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,18950742 0,21079744 ! spliceosome assembly GO:0000245 67 32 0,000 0,18950742 0,21070003 ! spindle organization GO:0007051 46 32 0,000 0,18950742 0,21060271 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,18950742 0,21050548 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,18950742 0,21040833 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,18950742 0,21031128 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,18950742 0,21021432 ! regulation of protein import into nucleus GO:0042306 63 32 0,000 0,18950742 0,21011745 ! muscle cell development GO:0055001 49 32 0,000 0,18950742 0,21002066 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,18950742 0,20992397 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,18950742 0,20982736 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,18950742 0,20973085 ! BMP signaling pathway GO:0030509 64 32 0,000 0,18950742 0,20963442 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,18950742 0,20953808 ! gene silencing GO:0016458 65 32 0,000 0,18950742 0,20944183 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,19481462 0,21520844 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,19481462 0,21510967 ! protein targeting to membrane GO:0006612 68 33 0,000 0,19481462 0,215011 ! ceramide metabolic process GO:0006672 64 33 0,000 0,19481462 0,21491242 ! formation of primary germ layer GO:0001704 72 33 0,000 0,19481462 0,21481392 ! cell fate specification GO:0001708 52 33 0,000 0,19481462 0,21471552 ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,19481462 0,21461721 ! adult locomotory behavior GO:0008344 59 33 0,000 0,19481462 0,21451898 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,19481462 0,21442085 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,19481462 0,21432281 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,20008724 0,22002281 ! glial cell differentiation GO:0010001 63 34 0,000 0,20008724 0,21992229 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,20008724 0,21982187 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,20008724 0,21972154 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,20008724 0,21962131 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,20008724 0,21952116 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,20008724 0,2194211 ! spermatid development GO:0007286 63 34 0,000 0,20008724 0,21932114 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,20008724 0,21922127 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,20008724 0,21912149 ! placenta development GO:0001890 53 34 0,000 0,20008724 0,21902179 ! negative regulation of secretion GO:0051048 63 35 0,000 0,20532551 0,22465356 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,20532551 0,22455144 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,20532551 0,22444942 ! odontogenesis GO:0042476 66 35 0,000 0,20532551 0,22434749 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,20532551 0,22424565 ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 0,20532551 0,22414391 ! cytokine production GO:0001816 59 35 0,000 0,20532551 0,22404226 ! vesicle localization GO:0051648 64 35 0,000 0,20532551 0,2239407 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,21052965 0,22951261 ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,21052965 0,22940866 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,21052965 0,22930481 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,21052965 0,22920105 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,21052965 0,22909739 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,21052965 0,22899382 ! regulation of proteolysis GO:0030162 72 36 0,000 0,21052965 0,22889034 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,21052965 0,22878696 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,21052965 0,22868367 ! embryonic organ development GO:0048568 57 36 0,000 0,21052965 0,22858047 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,21052965 0,22847737 ! RNA export from nucleus GO:0006405 56 37 0,000 0,21569988 0,23398282 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,21569988 0,23387738 ! meiosis I GO:0007127 65 37 0,000 0,21569988 0,23377203 ! sister chromatid segregation GO:0000819 58 37 0,000 0,21569988 0,23366677 ! actomyosin structure organization GO:0031032 62 37 0,000 0,21569988 0,23356161 ! organic anion transport GO:0015711 68 37 0,000 0,21569988 0,23345655 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,21569988 0,23335157 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,21569988 0,2332467 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,21569988 0,23314191 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,21569988 0,23303723 GO:0015986|ATP synthesis coupled proton transport, ! spermatid differentiation GO:0048515 66 37 0,000 0,21569988 0,23293263 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,22083642 0,23837255 GO:0006956|complement activation, ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,22083642 0,23826566 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,22083642 0,23815886 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,22083642 0,23805216 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,22083642 0,23794555 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,22083642 0,23783904 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,22083642 0,23773263 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,22083642 0,2376263 ! mRNA catabolic process GO:0006402 71 39 0,000 0,22593949 0,24300867 ! ion transmembrane transport GO:0034220 66 39 0,000 0,22593949 0,24290009 ! RNA modification GO:0009451 57 39 0,000 0,22593949 0,2427916 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,22593949 0,24268322 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,2310093 0,24801802 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,2310093 0,2479074 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,2310093 0,24779687 ! feeding behavior GO:0007631 59 40 0,000 0,2310093 0,24768644 ! negative regulation of binding GO:0051100 72 40 0,000 0,2310093 0,24757612 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,2310093 0,24746589 ! maintenance of protein location GO:0045185 91 40 0,000 0,2310093 0,24735575 ! cytokinesis GO:0000910 72 40 0,000 0,2310093 0,24724572 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,23604608 0,25252417 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,23604608 0,25241194 ! gliogenesis GO:0042063 88 41 0,000 0,23604608 0,25229981 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,23604608 0,25218777 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,23604608 0,25207584 ! polyol metabolic process GO:0019751 66 41 0,000 0,23604608 0,25196401 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,24105003 0,2571913 ! regulation of tube size GO:0035150 71 42 0,000 0,24105003 0,2570773 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,24105003 0,25696339 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,24105003 0,25684959 ! regulation of protein secretion GO:0050708 71 42 0,000 0,24105003 0,25673589 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,24105003 0,25662229 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,24602138 0,26179895 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,24602138 0,26168322 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,24602138 0,26156758 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,24602138 0,26145205 ! glucose transport GO:0015758 65 43 0,000 0,24602138 0,26133661 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,24602138 0,26122129 ! striated muscle contraction GO:0006941 77 43 0,000 0,24602138 0,26110606 ! phagocytosis GO:0006909 90 43 0,000 0,24602138 0,26099093 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,24602138 0,26087591 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,25096032 0,26599583 ! hexose transport GO:0008645 67 44 0,000 0,25096032 0,2658787 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,25096032 0,26576168 ! double-strand break repair GO:0006302 81 44 0,000 0,25096032 0,26564476 ! biopolymer methylation GO:0043414 84 44 0,000 0,25096032 0,26552794 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,25096032 0,26541122 ! maintenance of location in cell GO:0051651 97 44 0,000 0,25096032 0,26529461 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,25586707 0,27036284 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,25586707 0,27024415 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,25586707 0,27012557 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,25586707 0,2700071 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,25586707 0,26988872 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,26074185 0,27491012 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,26074185 0,2747897 ! response to calcium ion GO:0051592 81 47 0,000 0,26558485 0,27977108 ! endosome transport GO:0016197 108 47 0,000 0,26558485 0,27964864 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,26558485 0,27952631 ! methylation GO:0032259 90 47 0,000 0,26558485 0,27940409 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,27039628 0,28434154 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,27039628 0,28421732 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,27517635 0,28911542 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,27517635 0,28898922 ! regulation of ion transport GO:0043269 77 49 0,000 0,27517635 0,28886313 ! peptide metabolic process GO:0006518 76 49 0,000 0,27517635 0,28873716 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,27517635 0,28861129 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,27517635 0,28848553 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,27517635 0,28835989 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,27517635 0,28823435 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,27992526 0,29308102 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,27992526 0,29295354 ! excretion GO:0007588 83 51 0,000 0,28464322 0,29776156 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,28464322 0,29763215 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,28464322 0,29750286 ! amino acid activation GO:0043038 92 52 0,000 0,28933041 0,30227051 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 76 53 0,000 0,29398705 0,30700211 ! RNA catabolic process GO:0006401 93 53 0,000 0,29398705 0,30686892 ! regulation of translational initiation GO:0006446 82 53 0,000 0,29398705 0,30673584 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,29398705 0,30660288 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,29398705 0,30647004 ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,29861334 0,31115794 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,29861334 0,31102324 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,29861334 0,31088866 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,29861334 0,31075419 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,29861334 0,31061984 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,30320946 0,31526446 ! gastrulation GO:0007369 112 55 0,000 0,30320946 0,31512827 ! RNA elongation GO:0006354 79 55 0,000 0,30320946 0,31499221 ! sensory perception of smell GO:0007608 80 56 0,000 0,30777561 0,31959781 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,30777561 0,31945993 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,30777561 0,31932217 ! proton transport GO:0015992 94 56 0,000 0,30777561 0,31918454 ! hydrogen transport GO:0006818 97 58 0,000 0,3168188 0,32842138 ! regulation of endocytosis GO:0030100 91 58 0,000 0,3168188 0,32827994 ! adult behavior GO:0030534 99 58 0,000 0,3168188 0,32813863 ! positive regulation of secretion GO:0051047 95 59 0,000 0,32129622 0,33263283 ! skeletal system morphogenesis GO:0048705 105 59 0,000 0,32129622 0,33248976 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,32129622 0,33234682 GO:0032313|regulation of Rab GTPase activity, ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,32574444 0,33680323 ! camera-type eye development GO:0043010 116 60 0,000 0,32574444 0,33665856 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,33016365 0,34107933 ! tRNA processing GO:0008033 89 61 0,000 0,33016365 0,34093294 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,33016365 0,34078668 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,33455405 0,34517026 ! regulation of mitosis GO:0007088 105 63 0,000 0,33891582 0,34952055 GO:0051783|regulation of nuclear division, ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,33891582 0,3493708 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,33891582 0,34922118 ! cell redox homeostasis GO:0045454 102 64 0,000 0,34324913 0,35353485 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,34324913 0,35338358 ! single fertilization GO:0007338 75 64 0,000 0,34324913 0,35323243 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,34755419 0,35750979 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,35183117 0,36175462 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,35183117 0,36160009 ! extracellular matrix organization GO:0030198 133 66 0,000 0,35183117 0,36144569 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,35608026 0,36565476 ! chromosome segregation GO:0007059 113 67 0,000 0,35608026 0,36549876 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,35608026 0,3653429 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,36030163 0,36951651 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,36030163 0,36935906 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,36030163 0,36920176 ! cell cycle checkpoint GO:0000075 137 69 0,000 0,36449547 0,37334018 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,36449547 0,37318132 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,36449547 0,37302258 ! antigen processing and presentation GO:0019882 104 69 0,000 0,36449547 0,37286398 ! amine catabolic process GO:0009310 117 71 0,000 0,37280125 0,38119839 ! acute inflammatory response GO:0002526 113 72 0,000 0,37691355 0,38523959 ! carbohydrate transport GO:0008643 110 72 0,000 0,37691355 0,38507601 ! regulation of blood pressure GO:0008217 125 73 0,000 0,38099902 0,38908474 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,38099902 0,38891966 ! fertilization GO:0009566 90 73 0,000 0,38099902 0,38875473 ! transition metal ion transport GO:0000041 126 74 0,000 0,38505784 0,39272962 ! neurotransmitter transport GO:0006836 123 74 0,000 0,38505784 0,3925632 ! meiosis GO:0007126 121 74 0,000 0,38505784 0,39239693 GO:0051327|M phase of meiotic cell cycle, ! exocytosis GO:0006887 133 74 0,000 0,38505784 0,39223081 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,38505784 0,39206482 ! eye development GO:0001654 143 74 0,000 0,38505784 0,39189897 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,38909018 0,39583551 ! meiotic cell cycle GO:0051321 122 75 0,000 0,38909018 0,39566821 ! defense response to bacterium GO:0042742 89 76 0,000 0,39309621 0,39957308 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,39309621 0,39940435 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,39707611 0,4032778 ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,40103004 0,40712163 ! negative regulation of organelle organization GO:0010639 161 78 0,000 0,40103004 0,40694992 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,40495817 0,41076279 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,40495817 0,4105897 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,40495817 0,41041674 ! muscle cell differentiation GO:0042692 159 80 0,000 0,40886066 0,41419737 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,40886066 0,41402305 ! protein import into nucleus GO:0006606 158 80 0,000 0,40886066 0,41384887 ! digestion GO:0007586 112 81 0,000 0,4127377 0,41759752 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,4127377 0,41742198 ! nuclear import GO:0051170 161 81 0,000 0,4127377 0,4172466 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,41658943 0,42096353 ! response to unfolded protein GO:0006986 131 85 0,000 0,42799447 0,43230676 ! nucleosome assembly GO:0006334 122 85 0,000 0,42799447 0,43212535 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,42799447 0,43194409 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,43174664 0,43554818 ! chromatin assembly GO:0031497 124 86 0,000 0,43174664 0,43536564 ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,43547432 0,4389406 ! protein localization in nucleus GO:0034504 176 87 0,000 0,43547432 0,43875679 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,43917767 0,44230283 ! cellular defense response GO:0006968 114 89 0,000 0,44285684 0,44582158 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,44651201 0,44931321 ! sterol metabolic process GO:0016125 152 91 0,000 0,45014331 0,45277793 ! nucleosome organization GO:0034728 138 92 0,000 0,45375091 0,45621591 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,45375091 0,45602535 ! vitamin metabolic process GO:0006766 139 92 0,000 0,45375091 0,45583494 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,45733496 0,4592437 ! transcription initiation GO:0006352 153 94 0,000 0,46089561 0,46262613 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,46794733 0,46950845 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,46794733 0,46931274 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,4714387 0,47261729 ! protein ubiquitination GO:0016567 217 97 0,000 0,4714387 0,47242045 ! hormone metabolic process GO:0042445 157 97 0,000 0,4714387 0,47222377 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,47490727 0,47550016 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,47490727 0,47530237 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,4783532 0,4785521 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,4783532 0,4783532