pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6695-VanDeVijver-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/vantveer-oligo_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! positive regulation of glucose metabolic process GO:0010907 5 5 2,000 4,03E-06 7,427E-03 ! prostate gland development GO:0030850 5 5 2,000 4,03E-06 3,714E-03 ! positive regulation of catabolic process GO:0009896 16 16 3,000 4,939E-06 3,034E-03 ! positive regulation of cell migration GO:0030335 36 36 4,000 6,399E-06 2,948E-03 ! regulation of fibroblast proliferation GO:0048145 17 17 3,000 6,423E-06 2,368E-03 ! cell junction assembly GO:0034329 18 17 3,000 6,423E-06 1,973E-03 ! ER overload response GO:0006983 6 6 2,000 8,017E-06 2,111E-03 ! regulation of cellular carbohydrate catabolic process GO:0043471 6 6 2,000 8,017E-06 1,847E-03 GO:0043470|regulation of carbohydrate catabolic process, GO:0006110|regulation of glycolysis, ! positive regulation of cell motion GO:0051272 39 39 4,000 9,607E-06 1,967E-03 ! regulation of cell migration GO:0030334 71 71 5,000 1,365E-05 2,515E-03 ! positive regulation of cellular catabolic process GO:0031331 7 7 2,000 1,396E-05 2,338E-03 ! positive regulation of carbohydrate metabolic process GO:0045913 7 7 2,000 1,396E-05 2,143E-03 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! cell junction organization GO:0034330 23 22 3,000 1,92E-05 2,722E-03 ! regulation of generation of precursor metabolites and energy GO:0043467 8 8 2,000 2,221E-05 2,924E-03 ! regulation of locomotion GO:0040012 79 79 5,000 2,53E-05 3,108E-03 ! regulation of cell motion GO:0051270 79 79 5,000 2,53E-05 2,914E-03 ! glucose homeostasis GO:0042593 24 24 3,000 2,758E-05 2,99E-03 GO:0033500|carbohydrate homeostasis, ! positive regulation of MAP kinase activity GO:0043406 50 49 4,000 3,006E-05 3,077E-03 ! regulation of gene-specific transcription GO:0032583 25 25 3,000 3,265E-05 3,167E-03 ! regulation of intracellular protein transport GO:0033157 25 25 3,000 3,265E-05 3,008E-03 ! regulation of nitric-oxide synthase activity GO:0050999 9 9 2,000 3,314E-05 2,908E-03 ! positive regulation of endothelial cell proliferation GO:0001938 9 9 2,000 3,314E-05 2,776E-03 ! positive regulation of protein kinase activity GO:0045860 89 86 5,000 4,11E-05 3,293E-03 ! regulation of nucleocytoplasmic transport GO:0046822 27 27 3,000 4,479E-05 3,439E-03 ! positive regulation of transferase activity GO:0051347 91 88 5,000 4,683E-05 3,453E-03 GO:0033674|positive regulation of kinase activity, ! regulation of glucose metabolic process GO:0010906 10 10 2,000 4,708E-05 3,338E-03 ! negative regulation of nucleocytoplasmic transport GO:0046823 10 10 2,000 4,708E-05 3,214E-03 ! cell-substrate junction assembly GO:0007044 11 10 2,000 4,708E-05 3,099E-03 ! regulation of erythrocyte differentiation GO:0045646 10 10 2,000 4,708E-05 2,992E-03 ! epithelial to mesenchymal transition GO:0001837 10 10 2,000 4,708E-05 2,893E-03 ! protein amino acid autophosphorylation GO:0046777 28 28 3,000 5,196E-05 3,089E-03 ! regulation of epithelial cell proliferation GO:0050678 29 29 3,000 5,994E-05 3,452E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 11 11 2,000 6,439E-05 3,596E-03 ! regulation of monooxygenase activity GO:0032768 11 11 2,000 6,439E-05 3,491E-03 ! regulation of cellular carbohydrate metabolic process GO:0010675 11 11 2,000 6,439E-05 3,391E-03 GO:0006109|regulation of carbohydrate metabolic process, ! regulation of intracellular transport GO:0032386 31 31 3,000 7,853E-05 4,02E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 13 13 2,000 1,104E-04 5,501E-03 ! response to endoplasmic reticulum stress GO:0034976 13 13 2,000 1,104E-04 5,356E-03 ! negative regulation of intracellular transport GO:0032387 13 13 2,000 1,104E-04 5,219E-03 ! protein tetramerization GO:0051262 13 13 2,000 1,104E-04 5,088E-03 ! regulation of angiogenesis GO:0045765 35 34 3,000 1,138E-04 5,116E-03 ! regulation of MAP kinase activity GO:0043405 67 66 4,000 1,279E-04 5,61E-03 ! positive regulation of epithelial cell proliferation GO:0050679 14 14 2,000 1,398E-04 5,992E-03 ! lung development GO:0030324 38 37 3,000 1,594E-04 6,677E-03 ! wound healing GO:0042060 74 70 4,000 1,692E-04 6,932E-03 ! positive regulation of fibroblast proliferation GO:0048146 15 15 2,000 1,738E-04 6,964E-03 ! insulin receptor signaling pathway GO:0008286 17 15 2,000 1,738E-04 6,816E-03 ! ER-nuclear signaling pathway GO:0006984 15 15 2,000 1,738E-04 6,674E-03 ! regulation of homeostatic process GO:0032844 38 38 3,000 1,772E-04 6,664E-03 ! respiratory system development GO:0060541 40 39 3,000 1,963E-04 7,236E-03 ! protein oligomerization GO:0051259 39 39 3,000 1,963E-04 7,094E-03 ! respiratory tube development GO:0030323 40 39 3,000 1,963E-04 6,958E-03 ! positive regulation of cell adhesion GO:0045785 17 17 2,000 2,57E-04 8,937E-03 ! tissue remodeling GO:0048771 17 17 2,000 2,57E-04 8,772E-03 ! regulation of oxidoreductase activity GO:0051341 17 17 2,000 2,57E-04 8,612E-03 ! cell morphogenesis involved in differentiation GO:0000904 82 77 4,000 2,655E-04 8,737E-03 ! regulation of cellular catabolic process GO:0031329 18 18 2,000 3,068E-04 9,919E-03 ! regulation of endothelial cell proliferation GO:0001936 19 19 2,000 3,623E-04 0,01151395 ! placenta development GO:0001890 19 19 2,000 3,623E-04 0,0113188 ! regulation of catabolic process GO:0009894 48 47 3,000 4,071E-04 0,01250621 ! positive regulation of gene-specific transcription GO:0043193 20 20 2,000 4,24E-04 0,01281108 ! regulation of anatomical structure morphogenesis GO:0022603 90 86 4,000 4,446E-04 0,01321613 ! heart development GO:0007507 90 87 4,000 4,69E-04 0,01372112 ! gland development GO:0048732 51 49 3,000 4,783E-04 0,01377306 ! cell cycle arrest GO:0007050 49 49 3,000 4,783E-04 0,01356117 ! G1/S transition of mitotic cell cycle GO:0000082 21 21 2,000 4,921E-04 0,01374046 ! cellular response to insulin stimulus GO:0032869 23 21 2,000 4,921E-04 0,01353538 ! negative regulation of protein transport GO:0051224 21 21 2,000 4,921E-04 0,01333633 ! hemoglobin biosynthetic process GO:0042541 5 5 1,000 5,522E-04 0,0147506 ! mRNA stabilization GO:0048255 5 5 1,000 5,522E-04 0,01453987 GO:0043489|RNA stabilization, ! neurotransmitter uptake GO:0001504 5 5 1,000 5,522E-04 0,01433509 ! memory GO:0007613 5 5 1,000 5,522E-04 0,01413599 ! heart looping GO:0001947 5 5 1,000 5,522E-04 0,01394234 ! endocrine pancreas development GO:0031018 5 5 1,000 5,522E-04 0,01375393 ! indolalkylamine metabolic process GO:0006586 5 5 1,000 5,522E-04 0,01357055 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phospholipase A2 activity GO:0032429 5 5 1,000 5,522E-04 0,01339199 ! regulation of vascular endothelial growth factor production GO:0010574 5 5 1,000 5,522E-04 0,01321807 ! wound healing, spreading of epidermal cells GO:0035313 5 5 1,000 5,522E-04 0,0130486 ! protein heterooligomerization GO:0051291 5 5 1,000 5,522E-04 0,01288343 ! positive regulation of monooxygenase activity GO:0032770 5 5 1,000 5,522E-04 0,01272239 ! T cell lineage commitment GO:0002360 5 5 1,000 5,522E-04 0,01256532 ! regulation of hormone metabolic process GO:0032350 5 5 1,000 5,522E-04 0,01241209 ! peptidyl-lysine modification GO:0018205 5 5 1,000 5,522E-04 0,01226254 ! negative regulation of neuroblast proliferation GO:0007406 5 5 1,000 5,522E-04 0,01211656 ! positive regulation of erythrocyte differentiation GO:0045648 5 5 1,000 5,522E-04 0,01197401 ! positive regulation of blood vessel endothelial cell migration GO:0043536 5 5 1,000 5,522E-04 0,01183478 ! interphase of mitotic cell cycle GO:0051329 52 51 3,000 5,579E-04 0,01181785 GO:0051325|interphase, ! response to hypoxia GO:0001666 53 53 3,000 6,465E-04 0,01353882 ! regulation of protein transport GO:0051223 53 53 3,000 6,465E-04 0,0133867 GO:0070201|regulation of establishment of protein localization, ! response to oxygen levels GO:0070482 55 54 3,000 6,943E-04 0,01421763 ! reproductive developmental process GO:0003006 56 56 3,000 7,974E-04 0,01614997 ! posttranscriptional regulation of gene expression GO:0010608 98 98 4,000 8,098E-04 0,01622172 ! N-terminal protein amino acid modification GO:0031365 6 6 1,000 8,244E-04 0,01633655 GO:0018409|peptide or protein amino-terminal blocking, ! virus-host interaction GO:0019048 6 6 1,000 8,244E-04 0,01616276 ! regulation of positive chemotaxis GO:0050926 6 6 1,000 8,244E-04 0,01599262 GO:0050927|positive regulation of positive chemotaxis, ! cytoplasmic sequestering of transcription factor GO:0042994 6 6 1,000 8,244E-04 0,01582603 ! focal adhesion formation GO:0048041 7 6 1,000 8,244E-04 0,01566288 ! negative regulation of T cell proliferation GO:0042130 6 6 1,000 8,244E-04 0,01550305 GO:0070667|negative regulation of mast cell proliferation, ! regulation of vascular permeability GO:0043114 6 6 1,000 8,244E-04 0,01534645 ! peptidyl-serine phosphorylation GO:0018105 6 6 1,000 8,244E-04 0,01519299 ! L-amino acid transport GO:0015807 6 6 1,000 8,244E-04 0,01504256 ! regulation of bone resorption GO:0045124 6 6 1,000 8,244E-04 0,01489509 ! G1 DNA damage checkpoint GO:0031571 6 6 1,000 8,244E-04 0,01475048 ! regulation of T cell differentiation in the thymus GO:0033081 6 6 1,000 8,244E-04 0,01460864 ! phosphoinositide 3-kinase cascade GO:0014065 6 6 1,000 8,244E-04 0,01446951 ! nitric oxide metabolic process GO:0046209 6 6 1,000 8,244E-04 0,01433301 GO:0006809|nitric oxide biosynthetic process, ! regulation of embryonic development GO:0045995 6 6 1,000 8,244E-04 0,01419906 ! localization within membrane GO:0051668 6 6 1,000 8,244E-04 0,01406758 ! heart morphogenesis GO:0003007 25 25 2,000 8,33E-04 0,01408419 ! regulation of protein localization GO:0032880 58 57 3,000 8,528E-04 0,01428903 ! response to insulin stimulus GO:0032868 28 26 2,000 9,366E-04 0,0155513 ! peptidyl-amino acid modification GO:0018193 61 59 3,000 9,718E-04 0,01599075 ! mesenchymal cell development GO:0014031 29 27 2,000 1,048E-03 0,01709425 GO:0060485|mesenchyme development, GO:0048762|mesenchymal cell differentiation, ! regulation of chemokine production GO:0032642 7 7 1,000 1,149E-03 0,01856782 ! axis specification GO:0009798 7 7 1,000 1,149E-03 0,01840636 ! hemoglobin metabolic process GO:0020027 7 7 1,000 1,149E-03 0,01824768 ! regulation of mRNA processing GO:0050684 7 7 1,000 1,149E-03 0,01809172 ! negative regulation of lymphocyte proliferation GO:0050672 7 7 1,000 1,149E-03 0,0179384 GO:0032945|negative regulation of mononuclear cell proliferation, GO:0070664|negative regulation of leukocyte proliferation, ! response to X-ray GO:0010165 7 7 1,000 1,149E-03 0,01778765 ! regulation of intracellular pH GO:0051453 7 7 1,000 1,149E-03 0,01763942 ! platelet activation GO:0030168 8 7 1,000 1,149E-03 0,01749364 ! response to gamma radiation GO:0010332 8 7 1,000 1,149E-03 0,01735025 ! synaptic transmission, cholinergic GO:0007271 7 7 1,000 1,149E-03 0,01720919 ! regulation of mRNA stability GO:0043488 7 7 1,000 1,149E-03 0,01707041 ! negative regulation of T cell activation GO:0050868 7 7 1,000 1,149E-03 0,01693385 ! positive regulation of cell cycle GO:0045787 29 29 2,000 1,295E-03 0,0189485 ! response to UV GO:0009411 29 29 2,000 1,295E-03 0,0187993 ! positive regulation of translation GO:0045727 8 8 1,000 1,524E-03 0,02194269 ! negative regulation of bone remodeling GO:0046851 8 8 1,000 1,524E-03 0,02177259 ! negative regulation of transcription factor import into nucleus GO:0042992 8 8 1,000 1,524E-03 0,02160511 ! pancreas development GO:0031016 8 8 1,000 1,524E-03 0,02144019 ! cell-cell junction assembly GO:0007043 8 8 1,000 1,524E-03 0,02127776 ! positive regulation of endothelial cell migration GO:0010595 8 8 1,000 1,524E-03 0,02111778 ! sex determination GO:0007530 8 8 1,000 1,524E-03 0,02096018 ! plasma membrane fusion GO:0045026 8 8 1,000 1,524E-03 0,02080492 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 8 8 1,000 1,524E-03 0,02065194 ! peptidyl-serine modification GO:0018209 8 8 1,000 1,524E-03 0,0205012 ! positive regulation of leukocyte migration GO:0002687 8 8 1,000 1,524E-03 0,02035264 ! regulation of RNA stability GO:0043487 8 8 1,000 1,524E-03 0,02020622 ! release of cytochrome c from mitochondria GO:0001836 9 8 1,000 1,524E-03 0,02006189 ! cytoplasmic sequestering of protein GO:0051220 8 8 1,000 1,524E-03 0,0199196 ! regulation of translational initiation GO:0006446 31 31 2,000 1,577E-03 0,02046421 ! B cell activation GO:0042113 31 31 2,000 1,577E-03 0,02032111 ! regulation of DNA replication GO:0006275 32 31 2,000 1,577E-03 0,02017999 ! regulation of myeloid cell differentiation GO:0045637 32 31 2,000 1,577E-03 0,02004082 ! regulation of cell size GO:0008361 68 68 3,000 1,654E-03 0,02087874 ! regulation of translation GO:0006417 69 69 3,000 1,746E-03 0,02189087 ! regulation of mitotic cell cycle GO:0007346 72 69 3,000 1,746E-03 0,02174296 ! positive regulation of cell size GO:0045793 9 9 1,000 1,95E-03 0,02411874 ! negative regulation of cell cycle process GO:0010948 9 9 1,000 1,95E-03 0,02395794 ! platelet-derived growth factor receptor signaling pathway GO:0048008 9 9 1,000 1,95E-03 0,02379928 ! L-glutamate transport GO:0015813 9 9 1,000 1,95E-03 0,02364271 GO:0015800|acidic amino acid transport, ! negative regulation of protein import into nucleus GO:0042308 9 9 1,000 1,95E-03 0,02348818 ! regulation of cellular pH GO:0030641 9 9 1,000 1,95E-03 0,02333566 ! histone acetylation GO:0016573 9 9 1,000 1,95E-03 0,02318511 ! positive regulation of oxidoreductase activity GO:0051353 9 9 1,000 1,95E-03 0,02303648 ! negative regulation of tissue remodeling GO:0034104 9 9 1,000 1,95E-03 0,02288976 ! regulation of leukocyte migration GO:0002685 9 9 1,000 1,95E-03 0,02274488 ! regulation of blood vessel endothelial cell migration GO:0043535 9 9 1,000 1,95E-03 0,02260183 ! regulation of bone remodeling GO:0046850 34 34 2,000 2,066E-03 0,02379551 ! response to peptide hormone stimulus GO:0043434 36 34 2,000 2,066E-03 0,02364771 ! regulation of tissue remodeling GO:0034103 35 35 2,000 2,247E-03 0,02556873 ! apoptotic mitochondrial changes GO:0008637 11 10 1,000 2,426E-03 0,02742589 ! neuromuscular junction development GO:0007528 10 10 1,000 2,426E-03 0,02725866 ! cytolysis GO:0019835 10 10 1,000 2,426E-03 0,02709346 ! positive regulation of neuron apoptosis GO:0043525 10 10 1,000 2,426E-03 0,02693024 ! negative regulation of homeostatic process GO:0032845 10 10 1,000 2,426E-03 0,02676899 ! regulation of mitosis GO:0007088 37 36 2,000 2,439E-03 0,0267544 GO:0051783|regulation of nuclear division, ! meiosis GO:0007126 37 37 2,000 2,64E-03 0,02878942 GO:0051327|M phase of meiotic cell cycle, ! negative regulation of growth GO:0045926 37 37 2,000 2,64E-03 0,02862007 ! adaptive immune response GO:0002250 37 37 2,000 2,64E-03 0,0284527 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! urogenital system development GO:0001655 38 38 2,000 2,851E-03 0,03054919 ! meiotic cell cycle GO:0051321 38 38 2,000 2,851E-03 0,0303726 ! G1 phase of mitotic cell cycle GO:0000080 12 11 1,000 2,95E-03 0,03124985 ! protein amino acid acetylation GO:0006473 11 11 1,000 2,95E-03 0,03107128 ! positive regulation of nucleocytoplasmic transport GO:0046824 11 11 1,000 2,95E-03 0,03089474 GO:0032388|positive regulation of intracellular transport, ! activation of MAPKK activity GO:0000186 12 11 1,000 2,95E-03 0,03072019 ! cellular response to starvation GO:0009267 11 11 1,000 2,95E-03 0,03054761 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 11 11 1,000 2,95E-03 0,03037695 ! G1/S transition checkpoint GO:0031575 12 11 1,000 2,95E-03 0,03020819 ! interaction with host GO:0051701 11 11 1,000 2,95E-03 0,03004129 ! negative regulation of angiogenesis GO:0016525 11 11 1,000 2,95E-03 0,02987623 ! muscle maintenance GO:0046716 12 11 1,000 2,95E-03 0,02971297 ! negative regulation of lymphocyte activation GO:0051250 11 11 1,000 2,95E-03 0,02955149 ! activation of MAPK activity GO:0000187 39 39 2,000 3,072E-03 0,03060639 ! response to unfolded protein GO:0006986 39 39 2,000 3,072E-03 0,03044184 ! MAPKKK cascade GO:0000165 82 81 3,000 3,144E-03 0,03098383 ! tube development GO:0035295 83 81 3,000 3,144E-03 0,03081902 ! positive regulation of protein catabolic process GO:0045732 12 12 1,000 3,523E-03 0,03435709 ! positive regulation of angiogenesis GO:0045766 12 12 1,000 3,523E-03 0,03417626 ! protein amino acid ADP-ribosylation GO:0006471 12 12 1,000 3,523E-03 0,03399733 ! heterophilic cell adhesion GO:0007157 12 12 1,000 3,523E-03 0,03382026 ! collagen metabolic process GO:0032963 12 12 1,000 3,523E-03 0,03364502 ! xenobiotic metabolic process GO:0006805 12 12 1,000 3,523E-03 0,0334716 ! regulation of chromosome organization GO:0033044 12 12 1,000 3,523E-03 0,03329995 ! somitogenesis GO:0001756 13 12 1,000 3,523E-03 0,03313005 ! G1 phase GO:0051318 13 12 1,000 3,523E-03 0,03296188 ! regulation of mitotic metaphase/anaphase transition GO:0030071 13 12 1,000 3,523E-03 0,0327954 ! cellular monovalent inorganic cation homeostasis GO:0030004 12 12 1,000 3,523E-03 0,0326306 ! regulation of cellular localization GO:0060341 86 85 3,000 3,742E-03 0,03448341 ! cell-substrate adhesion GO:0031589 43 42 2,000 3,798E-03 0,03482694 ! response to protein stimulus GO:0051789 42 42 2,000 3,798E-03 0,03465453 ! reproductive structure development GO:0048608 43 43 2,000 4,062E-03 0,03687397 ! mitochondrion organization GO:0007005 44 43 2,000 4,062E-03 0,03669321 ! positive regulation of DNA replication GO:0045740 14 13 1,000 4,144E-03 0,03725424 ! positive regulation of smooth muscle cell proliferation GO:0048661 13 13 1,000 4,144E-03 0,0370734 ! vasculogenesis GO:0001570 13 13 1,000 4,144E-03 0,0368943 ! mitochondrial membrane organization GO:0007006 13 13 1,000 4,144E-03 0,03671692 ! negative regulation of DNA replication GO:0008156 13 13 1,000 4,144E-03 0,03654124 ! multicellular organismal macromolecule metabolic process GO:0044259 13 13 1,000 4,144E-03 0,03636724 ! actin filament bundle formation GO:0051017 13 13 1,000 4,144E-03 0,03619488 ! cell aging GO:0007569 13 13 1,000 4,144E-03 0,03602415 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 13 13 1,000 4,144E-03 0,03585502 ! regulation of endothelial cell migration GO:0010594 13 13 1,000 4,144E-03 0,03568748 ! positive regulation of locomotion GO:0040017 13 13 1,000 4,144E-03 0,03552149 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, GO:0050920|regulation of chemotaxis, ! neural crest cell migration GO:0001755 14 13 1,000 4,144E-03 0,03535704 ! negative regulation of Wnt receptor signaling pathway GO:0030178 13 13 1,000 4,144E-03 0,0351941 ! negative regulation of leukocyte activation GO:0002695 13 13 1,000 4,144E-03 0,03503266 ! cell-cell junction organization GO:0045216 13 13 1,000 4,144E-03 0,03487269 ! regulation of cell-substrate adhesion GO:0010810 14 13 1,000 4,144E-03 0,03471418 GO:0001952|regulation of cell-matrix adhesion, ! activation of JUN kinase activity GO:0007257 13 13 1,000 4,144E-03 0,0345571 ! tissue homeostasis GO:0001894 13 13 1,000 4,144E-03 0,03440144 GO:0048871|multicellular organismal homeostasis, ! male gamete generation GO:0048232 90 88 3,000 4,239E-03 0,03503045 GO:0007283|spermatogenesis, ! regulation of DNA binding GO:0051101 47 45 2,000 4,621E-03 0,0380184 ! Wnt receptor signaling pathway GO:0016055 46 45 2,000 4,621E-03 0,03784943 ! cellular iron ion homeostasis GO:0006879 14 14 1,000 4,811E-03 0,03923465 ! protein amino acid acylation GO:0043543 14 14 1,000 4,811E-03 0,03906181 ! calcium-dependent cell-cell adhesion GO:0016339 14 14 1,000 4,811E-03 0,03889049 ! negative regulation of epithelial cell proliferation GO:0050680 14 14 1,000 4,811E-03 0,03872066 ! response to retinoic acid GO:0032526 14 14 1,000 4,811E-03 0,03855231 GO:0033189|response to vitamin A, ! peptide cross-linking GO:0018149 14 14 1,000 4,811E-03 0,03838542 ! regulation of behavior GO:0050795 14 14 1,000 4,811E-03 0,03821997 ! base-excision repair GO:0006284 14 14 1,000 4,811E-03 0,03805593 ! cellular response to hormone stimulus GO:0032870 48 46 2,000 4,917E-03 0,03872695 ! rhythmic process GO:0048511 47 47 2,000 5,225E-03 0,04097368 ! protein import into nucleus, translocation GO:0000060 15 15 1,000 5,525E-03 0,04314367 ! response to vitamin GO:0033273 15 15 1,000 5,525E-03 0,04296163 ! regulation of transcription factor import into nucleus GO:0042990 15 15 1,000 5,525E-03 0,04278112 ! complement activation, classical pathway GO:0006958 15 15 1,000 5,525E-03 0,04260212 ! response to starvation GO:0042594 15 15 1,000 5,525E-03 0,04242461 ! response to ionizing radiation GO:0010212 16 15 1,000 5,525E-03 0,04224858 ! positive regulation of myeloid cell differentiation GO:0045639 16 15 1,000 5,525E-03 0,042074 ! negative regulation of cell activation GO:0050866 15 15 1,000 5,525E-03 0,04190085 ! protein homooligomerization GO:0051260 15 15 1,000 5,525E-03 0,04172913 ! regulation of cell cycle process GO:0010564 50 48 2,000 5,543E-03 0,04169987 ! skeletal muscle tissue development GO:0007519 50 49 2,000 5,874E-03 0,04400517 GO:0060538|skeletal muscle organ development, ! regulation of DNA metabolic process GO:0051052 51 50 2,000 6,216E-03 0,04637825 ! negative regulation of transport GO:0051051 51 50 2,000 6,216E-03 0,04619124 ! anatomical structure homeostasis GO:0060249 51 50 2,000 6,216E-03 0,04600574 ! circadian rhythm GO:0007623 16 16 1,000 6,283E-03 0,04632176 ! positive regulation of mitosis GO:0045840 16 16 1,000 6,283E-03 0,04613721 GO:0051785|positive regulation of nuclear division, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 16 16 1,000 6,283E-03 0,04595413 ! segmentation GO:0035282 17 16 1,000 6,283E-03 0,04577249 ! iron ion homeostasis GO:0055072 16 16 1,000 6,283E-03 0,04559229 ! cellular response to nutrient levels GO:0031669 16 16 1,000 6,283E-03 0,04541349 ! regulation of JUN kinase activity GO:0043506 17 16 1,000 6,283E-03 0,0452361 GO:0043507|positive regulation of JUN kinase activity, ! response to xenobiotic stimulus GO:0009410 16 16 1,000 6,283E-03 0,04506008 ! negative regulation of transcription from RNA polymerase II promoter GO:0000122 103 100 3,000 6,67E-03 0,04764337 ! hemopoiesis GO:0030097 104 100 3,000 6,67E-03 0,04745942 ! response to light stimulus GO:0009416 53 52 2,000 6,935E-03 0,04915604 ! regulation of smooth muscle cell proliferation GO:0048660 17 17 1,000 7,087E-03 0,05004346 ! myelination GO:0042552 17 17 1,000 7,087E-03 0,04985246 ! leukocyte adhesion GO:0007159 17 17 1,000 7,087E-03 0,0496629 ! glucose transport GO:0015758 17 17 1,000 7,087E-03 0,04947479 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 17 17 1,000 7,087E-03 0,04928809 ! neural crest cell development GO:0014032 19 17 1,000 7,087E-03 0,0491028 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 18 17 1,000 7,087E-03 0,04891889 ! negative regulation of cell development GO:0010721 18 17 1,000 7,087E-03 0,04873636 GO:0050768|negative regulation of neurogenesis, ! cell recognition GO:0008037 18 17 1,000 7,087E-03 0,04855518 ! regulation of osteoblast differentiation GO:0045667 17 17 1,000 7,087E-03 0,04837535 ! embryonic organ development GO:0048568 17 17 1,000 7,087E-03 0,04819684 ! liver development GO:0001889 17 17 1,000 7,087E-03 0,04801965 ! hormone metabolic process GO:0042445 55 54 2,000 7,701E-03 0,0519903 ! cellular response to extracellular stimulus GO:0031668 18 18 1,000 7,935E-03 0,05336985 ! ensheathment of neurons GO:0007272 18 18 1,000 7,935E-03 0,05317578 GO:0008366|axon ensheathment, ! symbiosis, encompassing mutualism through parasitism GO:0044403 18 18 1,000 7,935E-03 0,05298312 ! meiosis I GO:0007127 18 18 1,000 7,935E-03 0,05279184 ! epidermal growth factor receptor signaling pathway GO:0007173 18 18 1,000 7,935E-03 0,05260194 ! hexose transport GO:0008645 18 18 1,000 7,935E-03 0,0524134 GO:0015749|monosaccharide transport, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 18 18 1,000 7,935E-03 0,05222621 ! negative regulation of DNA binding GO:0043392 19 18 1,000 7,935E-03 0,05204036 ! B cell differentiation GO:0030183 18 18 1,000 7,935E-03 0,05185581 ! in utero embryonic development GO:0001701 55 55 2,000 8,103E-03 0,05276689 ! regulation of cell adhesion GO:0030155 56 55 2,000 8,103E-03 0,05258109 ! DNA damage checkpoint GO:0000077 19 19 1,000 8,825E-03 0,05707076 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 19 19 1,000 8,825E-03 0,05687121 GO:0006956|complement activation, ! negative regulation of DNA metabolic process GO:0051053 19 19 1,000 8,825E-03 0,05667306 ! regulation of pH GO:0006885 19 19 1,000 8,825E-03 0,05647627 ! multicellular organismal metabolic process GO:0044236 19 19 1,000 8,825E-03 0,05628085 ! peptidyl-tyrosine phosphorylation GO:0018108 20 19 1,000 8,825E-03 0,05608678 ! cellular response to oxidative stress GO:0034599 19 19 1,000 8,825E-03 0,05589404 ! peripheral nervous system development GO:0007422 19 19 1,000 8,825E-03 0,05570263 ! hormone biosynthetic process GO:0042446 19 19 1,000 8,825E-03 0,05551252 ! biogenic amine biosynthetic process GO:0042401 20 19 1,000 8,825E-03 0,0553237 ! dorsal/ventral pattern formation GO:0009953 19 19 1,000 8,825E-03 0,05513616 ! regulation of cell shape GO:0008360 21 19 1,000 8,825E-03 0,05494989 ! response to heat GO:0009408 19 19 1,000 8,825E-03 0,05476487 ! regulation of binding GO:0051098 60 57 2,000 8,942E-03 0,05530113 ! negative regulation of binding GO:0051100 21 20 1,000 9,759E-03 0,06015243 ! peptidyl-tyrosine modification GO:0018212 21 20 1,000 9,759E-03 0,05995192 ! mitotic sister chromatid segregation GO:0000070 21 21 1,000 0,01073431 0,06572537 ! mammary gland development GO:0030879 23 21 1,000 0,01073431 0,06550773 ! organic anion transport GO:0015711 21 21 1,000 0,01073431 0,06529154 ! DNA integrity checkpoint GO:0031570 21 21 1,000 0,01073431 0,06507676 ! regulation of protein import into nucleus GO:0042306 21 21 1,000 0,01073431 0,0648634 ! regulation of action potential in neuron GO:0019228 21 21 1,000 0,01073431 0,06465142 ! negative regulation of hydrolase activity GO:0051346 21 21 1,000 0,01073431 0,06444083 ! regulation of protein amino acid phosphorylation GO:0001932 62 61 2,000 0,01076858 0,06443664 ! axonogenesis GO:0007409 66 62 2,000 0,01125657 0,0671387 ! positive regulation of transcription factor activity GO:0051091 22 22 1,000 0,01175107 0,06986201 GO:0090047|positive regulation of transcription regulator activity, ! positive regulation of DNA metabolic process GO:0051054 23 22 1,000 0,01175107 0,06963737 ! sister chromatid segregation GO:0000819 22 22 1,000 0,01175107 0,06941417 ! maintenance of protein location in cell GO:0032507 23 22 1,000 0,01175107 0,0691924 ! spindle organization GO:0007051 22 22 1,000 0,01175107 0,06897204 ! neuron migration GO:0001764 22 22 1,000 0,01175107 0,06875308 ! regulation of Wnt receptor signaling pathway GO:0030111 23 22 1,000 0,01175107 0,06853551 ! cytokinesis GO:0000910 23 22 1,000 0,01175107 0,06831931 ! positive regulation of protein metabolic process GO:0051247 64 64 2,000 0,01227054 0,0711151 ! regulation of hormone levels GO:0010817 66 65 2,000 0,01279662 0,07393158 ! epithelial cell differentiation GO:0030855 23 23 1,000 0,01280848 0,07376884 ! mitotic cell cycle checkpoint GO:0007093 24 23 1,000 0,01280848 0,07353903 ! endocrine system development GO:0035270 23 23 1,000 0,01280848 0,07331065 ! positive regulation of growth GO:0045927 23 23 1,000 0,01280848 0,07308368 ! monovalent inorganic cation homeostasis GO:0055067 23 23 1,000 0,01280848 0,07285811 ! calcium-mediated signaling GO:0019722 23 23 1,000 0,01280848 0,07263393 ! Rho protein signal transduction GO:0007266 24 23 1,000 0,01280848 0,07241113 ! regulation of JNK cascade GO:0046328 25 23 1,000 0,01280848 0,07218969 ! cell morphogenesis involved in neuron differentiation GO:0048667 72 67 2,000 0,01388723 0,07803098 GO:0048812|neuron projection morphogenesis, GO:0048858|cell projection morphogenesis, ! striated muscle tissue development GO:0014706 69 67 2,000 0,01388723 0,0777938 ! negative regulation of cell differentiation GO:0045596 68 67 2,000 0,01388723 0,07755806 ! mitochondrial transport GO:0006839 24 24 1,000 0,01390589 0,07742767 ! regulation of action potential GO:0001508 24 24 1,000 0,01390589 0,07719446 ! gliogenesis GO:0042063 24 24 1,000 0,01390589 0,07696264 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 26 24 1,000 0,01390589 0,07673222 ! T cell differentiation GO:0030217 24 24 1,000 0,01390589 0,07650316 ! maintenance of protein location GO:0045185 25 24 1,000 0,01390589 0,07627548 ! androgen receptor signaling pathway GO:0030521 24 24 1,000 0,01390589 0,07604914 ! glucan metabolic process GO:0044042 25 24 1,000 0,01390589 0,07582414 GO:0006073|cellular glucan metabolic process, GO:0005977|glycogen metabolic process, ! response to radiation GO:0009314 70 68 2,000 0,01445184 0,07856855 ! regionalization GO:0003002 70 69 2,000 0,01502938 0,08146805 ! response to nutrient levels GO:0031667 69 69 2,000 0,01502938 0,08122914 ! regulation of T cell proliferation GO:0042129 25 25 1,000 0,01504267 0,08106327 ! positive regulation of DNA binding GO:0043388 26 25 1,000 0,01504267 0,08082693 ! negative regulation of immune system process GO:0002683 25 25 1,000 0,01504267 0,08059197 ! positive regulation of cytokine production GO:0001819 25 25 1,000 0,01504267 0,08035837 ! cell part morphogenesis GO:0032990 75 70 2,000 0,01561987 0,08320065 ! muscle tissue development GO:0060537 72 70 2,000 0,01561987 0,08296088 ! positive regulation of binding GO:0051099 27 26 1,000 0,01621817 0,08589106 ! negative regulation of cell migration GO:0030336 26 26 1,000 0,01621817 0,08564496 ! induction of apoptosis by intracellular signals GO:0008629 26 26 1,000 0,01621817 0,08540026 ! regulation of T cell differentiation GO:0045580 26 26 1,000 0,01621817 0,08515695 ! double-strand break repair GO:0006302 27 26 1,000 0,01621817 0,08491503 ! maintenance of location in cell GO:0051651 27 26 1,000 0,01621817 0,08467448 ! synapse organization GO:0050808 26 26 1,000 0,01621817 0,08443528 ! positive regulation of hydrolase activity GO:0051345 72 72 2,000 0,01683988 0,08742505 ! response to extracellular stimulus GO:0009991 72 72 2,000 0,01683988 0,08717948 ! regulation of neurotransmitter levels GO:0001505 31 27 1,000 0,01743178 0,08999094 ! energy reserve metabolic process GO:0006112 28 27 1,000 0,01743178 0,08973957 ! learning or memory GO:0007611 28 27 1,000 0,01743178 0,0894896 ! activation of caspase activity GO:0006919 27 27 1,000 0,01743178 0,08924102 ! cell growth GO:0016049 27 27 1,000 0,01743178 0,08899381 ! stress-activated protein kinase signaling pathway GO:0031098 28 28 1,000 0,01868287 0,09511746 GO:0007254|JNK cascade, ! carbohydrate transport GO:0008643 28 28 1,000 0,01868287 0,09485543 ! keratinocyte differentiation GO:0030216 28 28 1,000 0,01868287 0,09459484 ! histone modification GO:0016570 28 28 1,000 0,01868287 0,09433567 ! regulation of mast cell proliferation GO:0070666 28 28 1,000 0,01868287 0,09407792 ! cartilage development GO:0051216 29 28 1,000 0,01868287 0,09382158 ! response to oxidative stress GO:0006979 76 75 2,000 0,01876782 0,09399209 ! viral reproductive process GO:0022415 29 29 1,000 0,01997082 0,09974587 ! branching morphogenesis of a tube GO:0048754 29 29 1,000 0,01997082 0,09947628 ! regulation of lymphocyte proliferation GO:0050670 29 29 1,000 0,01997082 0,09920815 GO:0032944|regulation of mononuclear cell proliferation, GO:0070663|regulation of leukocyte proliferation, ! covalent chromatin modification GO:0016569 29 29 1,000 0,01997082 0,09894146 ! positive regulation of protein transport GO:0051222 29 29 1,000 0,01997082 0,09867621 ! regulation of protein modification process GO:0031399 79 78 2,000 0,02081377 0,10256626 ! positive regulation of peptidase activity GO:0010952 30 30 1,000 0,02129504 0,10465803 GO:0043280|positive regulation of caspase activity, ! activation of phospholipase C activity GO:0007202 30 30 1,000 0,02129504 0,10437969 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of response to external stimulus GO:0032103 30 30 1,000 0,02129504 0,10410282 ! response to temperature stimulus GO:0009266 30 30 1,000 0,02129504 0,10382741 ! regulation of ossification GO:0030278 30 30 1,000 0,02129504 0,10355346 ! vascular process in circulatory system GO:0003018 31 30 1,000 0,02129504 0,10328095 ! immunoglobulin mediated immune response GO:0016064 30 30 1,000 0,02129504 0,10300987 GO:0019724|B cell mediated immunity, ! cellular amino acid derivative biosynthetic process GO:0042398 31 30 1,000 0,02129504 0,10274021 ! establishment of organelle localization GO:0051656 31 30 1,000 0,02129504 0,10247196 ! neuron projection development GO:0031175 85 80 2,000 0,02224349 0,10675715 ! skeletal muscle fiber development GO:0048741 31 31 1,000 0,02265493 0,10844942 ! membrane fusion GO:0006944 31 31 1,000 0,02265493 0,10816846 ! positive regulation of phospholipase activity GO:0010518 31 31 1,000 0,02265493 0,10788896 ! aging GO:0007568 32 31 1,000 0,02265493 0,10761089 ! epidermal cell differentiation GO:0009913 31 31 1,000 0,02265493 0,10733426 ! negative regulation of cell motion GO:0051271 31 31 1,000 0,02265493 0,10705904 ! lymphocyte activation GO:0046649 82 81 2,000 0,02297809 0,10830849 ! negative regulation of cell growth GO:0030308 32 32 1,000 0,02404988 0,11307124 ! muscle fiber development GO:0048747 32 32 1,000 0,02404988 0,11278353 ! regulation of phospholipase activity GO:0010517 32 32 1,000 0,02404988 0,11249728 ! cell maturation GO:0048469 32 32 1,000 0,02404988 0,11221247 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 32 32 1,000 0,02404988 0,11192911 ! morphogenesis of a branching structure GO:0001763 32 32 1,000 0,02404988 0,11164717 ! regulation of lymphocyte differentiation GO:0045619 32 32 1,000 0,02404988 0,11136665 ! positive regulation of lipase activity GO:0060193 32 32 1,000 0,02404988 0,11108754 ! protein maturation by peptide bond cleavage GO:0051605 32 32 1,000 0,02404988 0,11080982 ! maintenance of location GO:0051235 33 32 1,000 0,02404988 0,11053349 ! negative regulation of cell size GO:0045792 33 33 1,000 0,02547932 0,1168119 ! regulation of cellular response to stress GO:0080135 35 33 1,000 0,02547932 0,11652204 ! amino acid transport GO:0006865 33 33 1,000 0,02547932 0,11623362 ! activation of protein kinase activity GO:0032147 35 33 1,000 0,02547932 0,11594663 ! regulation of neuron apoptosis GO:0043523 34 33 1,000 0,02547932 0,11566104 ! nitrogen compound biosynthetic process GO:0044271 86 85 2,000 0,02604819 0,11795287 ! positive regulation of response to stimulus GO:0048584 86 85 2,000 0,02604819 0,11766377 ! cellular polysaccharide metabolic process GO:0044264 35 34 1,000 0,02694266 0,12140667 ! regulation of protein catabolic process GO:0042176 35 34 1,000 0,02694266 0,12111056 ! viral reproduction GO:0016032 34 34 1,000 0,02694266 0,12081588 ! acute inflammatory response GO:0002526 35 35 1,000 0,02843934 0,12721773 ! regulation of cyclin-dependent protein kinase activity GO:0000079 35 35 1,000 0,02843934 0,12690969 ! mesoderm development GO:0007498 35 35 1,000 0,02843934 0,12660315 ! regulation of cell morphogenesis GO:0022604 38 35 1,000 0,02843934 0,12629808 ! positive regulation of phosphorylation GO:0042327 35 35 1,000 0,02843934 0,12599448 ! positive regulation of phosphorus metabolic process GO:0010562 36 36 1,000 0,02996878 0,13245196 GO:0045937|positive regulation of phosphate metabolic process, ! positive regulation of organelle organization GO:0010638 36 36 1,000 0,02996878 0,13213509 ! integrin-mediated signaling pathway GO:0007229 36 36 1,000 0,02996878 0,13181973 ! regulation of lipase activity GO:0060191 36 36 1,000 0,02996878 0,13150587 ! activation of immune response GO:0002253 36 36 1,000 0,02996878 0,13119351 ! coagulation GO:0050817 39 36 1,000 0,02996878 0,13088262 GO:0007596|blood coagulation, ! negative regulation of cell cycle GO:0045786 92 91 2,000 0,03104773 0,13527416 ! regulation of transcription factor activity GO:0051090 38 37 1,000 0,03153043 0,13705326 GO:0090046|regulation of transcription regulator activity, ! negative regulation of protein kinase activity GO:0006469 37 37 1,000 0,03153043 0,13673078 ! response to drug GO:0042493 37 37 1,000 0,03153043 0,13640982 ! lymphocyte mediated immunity GO:0002449 37 37 1,000 0,03153043 0,13609036 ! DNA damage response, signal transduction GO:0042770 37 37 1,000 0,03153043 0,13577239 ! positive regulation of immune system process GO:0002684 92 92 2,000 0,03192684 0,13715888 ! neurotransmitter transport GO:0006836 40 38 1,000 0,03312373 0,14196985 ! cellular hormone metabolic process GO:0034754 39 38 1,000 0,03312373 0,14164045 ! negative regulation of kinase activity GO:0033673 38 38 1,000 0,03312373 0,14131258 ! cell-matrix adhesion GO:0007160 39 38 1,000 0,03312373 0,14098622 ! chromosome segregation GO:0007059 38 38 1,000 0,03312373 0,14066137 ! axon guidance GO:0007411 39 38 1,000 0,03312373 0,14033801 ! steroid hormone receptor signaling pathway GO:0030518 38 38 1,000 0,03312373 0,14001613 ! pattern specification process GO:0007389 96 94 2,000 0,03372417 0,14222802 ! hemostasis GO:0007599 42 39 1,000 0,03474813 0,1462119 ! nucleotide-excision repair GO:0006289 40 39 1,000 0,03474813 0,14587884 ! regulation of MAPKKK cascade GO:0043408 41 39 1,000 0,03474813 0,1455473 ! developmental maturation GO:0021700 39 39 1,000 0,03474813 0,14521726 ! lymphocyte differentiation GO:0030098 39 39 1,000 0,03474813 0,14488871 ! negative regulation of transferase activity GO:0051348 40 40 1,000 0,0364031 0,15144676 ! intracellular receptor-mediated signaling pathway GO:0030522 40 40 1,000 0,0364031 0,15110566 ! organelle localization GO:0051640 41 40 1,000 0,0364031 0,1507661 ! rRNA transcription GO:0009303 5 5 0,000 0,03723441 0,15386325 ! positive regulation of protein ubiquitination GO:0031398 5 5 0,000 0,03723441 0,15351904 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 5 5 0,000 0,03723441 0,15317636 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 5 5 0,000 0,03723441 0,15283521 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! neuron fate specification GO:0048665 5 5 0,000 0,03723441 0,15249558 ! reproductive cellular process GO:0048610 5 5 0,000 0,03723441 0,15215745 ! negative regulation of blood pressure GO:0045776 6 5 0,000 0,03723441 0,15182082 ! metencephalon development GO:0022037 5 5 0,000 0,03723441 0,15148567 ! water transport GO:0006833 5 5 0,000 0,03723441 0,15115201 GO:0042044|fluid transport, ! forebrain regionalization GO:0021871 5 5 0,000 0,03723441 0,1508198 ! DNA synthesis during DNA repair GO:0000731 5 5 0,000 0,03723441 0,15048906 ! positive regulation of B cell proliferation GO:0030890 5 5 0,000 0,03723441 0,15015976 ! glycerol metabolic process GO:0006071 5 5 0,000 0,03723441 0,1498319 ! regulation of cellular amine metabolic process GO:0033238 5 5 0,000 0,03723441 0,14950547 GO:0042053|regulation of dopamine metabolic process, GO:0042069|regulation of catecholamine metabolic process, ! meiotic prophase I GO:0007128 5 5 0,000 0,03723441 0,14918046 GO:0051324|prophase, ! cell volume homeostasis GO:0006884 5 5 0,000 0,03723441 0,14885686 ! regulation of epidermal growth factor receptor activity GO:0007176 5 5 0,000 0,03723441 0,14853465 GO:0010469|regulation of receptor activity, ! regulation of long-term neuronal synaptic plasticity GO:0048169 5 5 0,000 0,03723441 0,14821385 ! filopodium assembly GO:0046847 7 5 0,000 0,03723441 0,14789442 GO:0030035|microspike assembly, ! CTP metabolic process GO:0046036 5 5 0,000 0,03723441 0,14757637 GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0006241|CTP biosynthetic process, ! Golgi to endosome transport GO:0006895 5 5 0,000 0,03723441 0,14725968 ! GTP metabolic process GO:0046039 5 5 0,000 0,03723441 0,14694435 ! establishment of tissue polarity GO:0007164 5 5 0,000 0,03723441 0,14663036 ! positive regulation of cell-cell adhesion GO:0022409 5 5 0,000 0,03723441 0,14631772 ! regulation of neurotransmitter secretion GO:0046928 5 5 0,000 0,03723441 0,14600641 GO:0001956|positive regulation of neurotransmitter secretion, ! social behavior GO:0035176 5 5 0,000 0,03723441 0,14569641 ! macrophage chemotaxis GO:0048246 6 5 0,000 0,03723441 0,14538773 ! 2-oxoglutarate metabolic process GO:0006103 5 5 0,000 0,03723441 0,14508036 ! dopamine receptor signaling pathway GO:0007212 5 5 0,000 0,03723441 0,14477428 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 5 5 0,000 0,03723441 0,1444695 ! membrane hyperpolarization GO:0060081 5 5 0,000 0,03723441 0,14416599 ! response to lipid GO:0033993 5 5 0,000 0,03723441 0,14386375 ! erythrocyte maturation GO:0043249 5 5 0,000 0,03723441 0,14356278 ! hippocampus development GO:0021766 6 5 0,000 0,03723441 0,14326307 ! regulation of carbohydrate biosynthetic process GO:0043255 5 5 0,000 0,03723441 0,14296461 ! glucocorticoid metabolic process GO:0008211 5 5 0,000 0,03723441 0,14266738 ! middle ear morphogenesis GO:0042474 5 5 0,000 0,03723441 0,14237139 ! amyloid precursor protein catabolic process GO:0042987 5 5 0,000 0,03723441 0,14207663 ! mechanosensory behavior GO:0007638 5 5 0,000 0,03723441 0,14178308 ! negative regulation of endocytosis GO:0045806 5 5 0,000 0,03723441 0,14149074 ! response to interferon-gamma GO:0034341 5 5 0,000 0,03723441 0,14119961 ! pseudouridine synthesis GO:0001522 5 5 0,000 0,03723441 0,14090967 ! pH reduction GO:0045851 5 5 0,000 0,03723441 0,14062092 GO:0051452|intracellular pH reduction, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 5 5 0,000 0,03723441 0,14033335 ! lipopolysaccharide metabolic process GO:0008653 5 5 0,000 0,03723441 0,14004696 ! positive regulation of chemokine biosynthetic process GO:0045080 5 5 0,000 0,03723441 0,13976173 ! sphingoid biosynthetic process GO:0046520 5 5 0,000 0,03723441 0,13947766 GO:0046513|ceramide biosynthetic process, ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 5 5 0,000 0,03723441 0,13919475 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! thymic T cell selection GO:0045061 5 5 0,000 0,03723441 0,13891298 ! insulin-like growth factor receptor signaling pathway GO:0048009 5 5 0,000 0,03723441 0,13863234 ! photoreceptor cell maintenance GO:0045494 5 5 0,000 0,03723441 0,13835284 ! adrenal gland development GO:0030325 5 5 0,000 0,03723441 0,13807447 ! regulation of cardiac muscle hypertrophy GO:0010611 5 5 0,000 0,03723441 0,13779721 GO:0010612|regulation of cardiac muscle adaptation, GO:0014743|regulation of muscle hypertrophy, GO:0043502|regulation of muscle adaptation, ! melanocyte differentiation GO:0030318 5 5 0,000 0,03723441 0,13752106 GO:0050931|pigment cell differentiation, ! ovulation GO:0030728 5 5 0,000 0,03723441 0,13724602 ! astrocyte differentiation GO:0048708 5 5 0,000 0,03723441 0,13697208 ! mitochondrial respiratory chain complex assembly GO:0033108 5 5 0,000 0,03723441 0,13669922 GO:0032981|mitochondrial respiratory chain complex I assembly, GO:0010257|NADH dehydrogenase complex assembly, ! pituitary gland development GO:0021983 5 5 0,000 0,03723441 0,13642746 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 5 5 0,000 0,03723441 0,13615677 GO:0033135|regulation of peptidyl-serine phosphorylation, ! tyrosine metabolic process GO:0006570 5 5 0,000 0,03723441 0,13588715 ! cytoskeletal anchoring at plasma membrane GO:0007016 6 5 0,000 0,03723441 0,1356186 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 5 5 0,000 0,03723441 0,13535111 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, GO:0009164|nucleoside catabolic process, ! microtubule nucleation GO:0007020 5 5 0,000 0,03723441 0,13508467 ! regulation of interleukin-6 biosynthetic process GO:0045408 5 5 0,000 0,03723441 0,13481927 ! regulation of interleukin-8 biosynthetic process GO:0045414 5 5 0,000 0,03723441 0,13455492 ! muscle cell migration GO:0014812 5 5 0,000 0,03723441 0,13429161 ! phasic smooth muscle contraction GO:0014821 5 5 0,000 0,03723441 0,13402932 ! central nervous system neuron axonogenesis GO:0021955 6 5 0,000 0,03723441 0,13376805 GO:0021952|central nervous system projection neuron axonogenesis, ! sister chromatid cohesion GO:0007062 5 5 0,000 0,03723441 0,1335078 ! response to ATP GO:0033198 5 5 0,000 0,03723441 0,13324856 ! regulation of type I interferon production GO:0032479 5 5 0,000 0,03723441 0,13299033 ! regulation of appetite GO:0032098 5 5 0,000 0,03723441 0,1327331 GO:0032095|regulation of response to food, ! vesicle fusion GO:0006906 5 5 0,000 0,03723441 0,13247685 ! paraxial mesoderm development GO:0048339 5 5 0,000 0,03723441 0,1322216 ! regulation of the force of heart contraction GO:0002026 5 5 0,000 0,03723441 0,13196733 ! maintenance of protein location in nucleus GO:0051457 5 5 0,000 0,03723441 0,13171403 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,03723441 0,13146171 ! receptor clustering GO:0043113 5 5 0,000 0,03723441 0,13121035 ! neurotransmitter biosynthetic process GO:0042136 6 5 0,000 0,03723441 0,13095994 ! fear response GO:0042596 5 5 0,000 0,03723441 0,1307105 ! actin cytoskeleton reorganization GO:0031532 5 5 0,000 0,03723441 0,130462 ! lens development in camera-type eye GO:0002088 5 5 0,000 0,03723441 0,13021444 ! retinol metabolic process GO:0042572 5 5 0,000 0,03723441 0,12996782 ! corticosteroid receptor signaling pathway GO:0031958 5 5 0,000 0,03723441 0,12972214 GO:0042921|glucocorticoid receptor signaling pathway, ! temperature homeostasis GO:0001659 5 5 0,000 0,03723441 0,12947738 ! positive regulation of exocytosis GO:0045921 6 5 0,000 0,03723441 0,12923354 ! parturition GO:0007567 5 5 0,000 0,03723441 0,12899062 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,03723441 0,12874861 ! Schwann cell differentiation GO:0014037 5 5 0,000 0,03723441 0,12850751 ! acyl-CoA metabolic process GO:0006637 5 5 0,000 0,03723441 0,12826731 ! regulation of gliogenesis GO:0014013 5 5 0,000 0,03723441 0,128028 GO:0045685|regulation of glial cell differentiation, ! positive regulation of peptide secretion GO:0002793 5 5 0,000 0,03723441 0,12778959 ! response to UV-B GO:0010224 5 5 0,000 0,03723441 0,12755206 ! oligodendrocyte development GO:0014003 5 5 0,000 0,03723441 0,12731542 ! hyaluronan metabolic process GO:0030212 5 5 0,000 0,03723441 0,12707965 ! activated T cell proliferation GO:0050798 5 5 0,000 0,03723441 0,12684475 ! interaction with symbiont GO:0051702 5 5 0,000 0,03723441 0,12661072 ! cellular extravasation GO:0045123 5 5 0,000 0,03723441 0,12637755 ! positive regulation of axonogenesis GO:0050772 5 5 0,000 0,03723441 0,12614524 ! peptidyl-asparagine modification GO:0018196 5 5 0,000 0,03723441 0,12591378 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! positive regulation of phagocytosis GO:0050766 5 5 0,000 0,03723441 0,12568317 ! regulation of insulin receptor signaling pathway GO:0046626 5 5 0,000 0,03723441 0,1254534 ! antigen processing and presentation of exogenous antigen GO:0019884 5 5 0,000 0,03723441 0,12522447 ! enucleate erythrocyte differentiation GO:0043353 6 5 0,000 0,03723441 0,12499638 ! response to amine stimulus GO:0014075 5 5 0,000 0,03723441 0,12476911 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 5 5 0,000 0,03723441 0,12454267 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 5 5 0,000 0,03723441 0,12431705 ! synaptic vesicle exocytosis GO:0016079 6 5 0,000 0,03723441 0,12409224 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 5 5 0,000 0,03723441 0,12386825 ! glycosylceramide metabolic process GO:0006677 5 5 0,000 0,03723441 0,12364506 ! neuron recognition GO:0008038 5 5 0,000 0,03723441 0,12342268 ! negative regulation of focal adhesion formation GO:0051895 6 5 0,000 0,03723441 0,1232011 ! decidualization GO:0046697 5 5 0,000 0,03723441 0,12298031 ! hair follicle maturation GO:0048820 5 5 0,000 0,03723441 0,12276031 ! phosphatidylinositol biosynthetic process GO:0006661 5 5 0,000 0,03723441 0,12254109 ! regulation of mitochondrial membrane potential GO:0051881 5 5 0,000 0,03723441 0,12232266 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 0,03723441 0,122105 GO:0009155|purine deoxyribonucleotide catabolic process, ! regulation of interleukin-12 production GO:0032655 5 5 0,000 0,03723441 0,12188812 ! positive regulation of interleukin-6 production GO:0032755 5 5 0,000 0,03723441 0,121672 ! postreplication repair GO:0006301 5 5 0,000 0,03723441 0,12145666 ! spinal cord motor neuron differentiation GO:0021522 5 5 0,000 0,03723441 0,12124207 GO:0021517|ventral spinal cord development, ! cellular pigmentation GO:0033059 5 5 0,000 0,03723441 0,12102824 ! histone methylation GO:0016571 5 5 0,000 0,03723441 0,12081516 ! DNA methylation GO:0006306 5 5 0,000 0,03723441 0,12060283 GO:0006305|DNA alkylation, ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,03723441 0,12039125 ! positive regulation of immunoglobulin mediated immune response GO:0002891 5 5 0,000 0,03723441 0,1201804 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of interferon-gamma production GO:0032729 5 5 0,000 0,03723441 0,1199703 ! negative regulation of tumor necrosis factor production GO:0032720 5 5 0,000 0,03723441 0,11976093 ! intracellular cholesterol transport GO:0032367 5 5 0,000 0,03723441 0,11955228 GO:0032366|intracellular sterol transport, ! regulation of mast cell activation GO:0033003 5 5 0,000 0,03723441 0,11934437 ! morphogenesis of a polarized epithelium GO:0001738 5 5 0,000 0,03723441 0,11913717 ! regulation of transcription from RNA polymerase III promoter GO:0006359 5 5 0,000 0,03723441 0,11893069 ! regulation of inflammatory response to antigenic stimulus GO:0002861 5 5 0,000 0,03723441 0,11872493 ! sterol catabolic process GO:0016127 5 5 0,000 0,03723441 0,11851988 GO:0006707|cholesterol catabolic process, ! negative regulation of oxidoreductase activity GO:0051354 5 5 0,000 0,03723441 0,11831554 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 5 5 0,000 0,03723441 0,11811189 ! detection of biotic stimulus GO:0009595 5 5 0,000 0,03723441 0,11790895 ! regulation of immune response to tumor cell GO:0002837 5 5 0,000 0,03723441 0,11770671 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 5 5 0,000 0,03723441 0,11750516 ! zymogen activation GO:0031638 5 5 0,000 0,03723441 0,11730429 ! positive regulation of interleukin-1 beta secretion GO:0050718 5 5 0,000 0,03723441 0,11710411 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 5 5 0,000 0,03723441 0,11690462 GO:0002820|negative regulation of adaptive immune response, ! cellular response to nutrient GO:0031670 5 5 0,000 0,03723441 0,1167058 ! peptidyl-histidine modification GO:0018202 5 5 0,000 0,03723441 0,11650766 ! nucleosome positioning GO:0016584 5 5 0,000 0,03723441 0,11631019 ! regulation of isotype switching GO:0045191 5 5 0,000 0,03723441 0,11611339 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 5 5 0,000 0,03723441 0,11591725 ! negative regulation of neurological system process GO:0031645 5 5 0,000 0,03723441 0,11572177 ! regulation of myoblast differentiation GO:0045661 5 5 0,000 0,03723441 0,11552695 ! glutathione biosynthetic process GO:0006750 5 5 0,000 0,03723441 0,11533279 ! NADPH regeneration GO:0006740 5 5 0,000 0,03723441 0,11513928 GO:0006098|pentose-phosphate shunt, ! positive regulation of epidermis development GO:0045684 5 5 0,000 0,03723441 0,11494642 ! positive regulation of leukocyte chemotaxis GO:0002690 5 5 0,000 0,03723441 0,1147542 GO:0002688|regulation of leukocyte chemotaxis, ! musculoskeletal movement GO:0050881 5 5 0,000 0,03723441 0,11456262 GO:0050879|multicellular organismal movement, ! neuromuscular process controlling posture GO:0050884 5 5 0,000 0,03723441 0,11437168 ! sarcomere organization GO:0045214 5 5 0,000 0,03723441 0,11418138 ! regulation of epidermal cell differentiation GO:0045604 5 5 0,000 0,03723441 0,11399171 ! activation of NF-kappaB-inducing kinase activity GO:0007250 5 5 0,000 0,03723441 0,11380267 ! negative regulation of glucose transport GO:0010829 5 5 0,000 0,03723441 0,11361426 GO:0046325|negative regulation of glucose import, ! positive regulation of T-helper cell differentiation GO:0045624 5 5 0,000 0,03723441 0,11342646 GO:0045622|regulation of T-helper cell differentiation, ! oocyte differentiation GO:0009994 5 5 0,000 0,03723441 0,11323929 GO:0048599|oocyte development, ! dopamine biosynthetic process GO:0042416 5 5 0,000 0,03723441 0,11305274 ! regulation of protein homodimerization activity GO:0043496 6 5 0,000 0,03723441 0,11286679 ! spleen development GO:0048536 5 5 0,000 0,03723441 0,11268146 ! male genitalia development GO:0030539 5 5 0,000 0,03723441 0,11249674 ! nicotinamide nucleotide biosynthetic process GO:0019359 5 5 0,000 0,03723441 0,11231262 ! quaternary ammonium group transport GO:0015697 5 5 0,000 0,03723441 0,1121291 ! thyroid hormone metabolic process GO:0042403 5 5 0,000 0,03723441 0,11194618 ! leukocyte mediated cytotoxicity GO:0001909 5 5 0,000 0,03723441 0,11176386 ! positive regulation of viral reproduction GO:0048524 5 5 0,000 0,03723441 0,11158213 ! removal of superoxide radicals GO:0019430 6 5 0,000 0,03723441 0,11140099 ! myeloid cell homeostasis GO:0002262 5 5 0,000 0,03723441 0,11122044 ! regulation of fatty acid oxidation GO:0046320 5 5 0,000 0,03723441 0,11104047 ! regulation of Rac protein signal transduction GO:0035020 5 5 0,000 0,03723441 0,11086108 ! ATP catabolic process GO:0006200 5 5 0,000 0,03723441 0,11068228 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,03723441 0,11050404 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 5 5 0,000 0,03723441 0,11032638 ! blastocyst formation GO:0001825 5 5 0,000 0,03723441 0,11014929 ! regulation of fibrinolysis GO:0051917 5 5 0,000 0,03723441 0,10997277 ! embryonic gut development GO:0048566 5 5 0,000 0,03723441 0,10979682 ! negative regulation of organic acid transport GO:0032891 5 5 0,000 0,03723441 0,10962142 ! pyrimidine base metabolic process GO:0006206 5 5 0,000 0,03723441 0,10944659 ! activation of innate immune response GO:0002218 5 5 0,000 0,03723441 0,10927231 GO:0002758|innate immune response-activating signal transduction, ! catecholamine transport GO:0051937 5 5 0,000 0,03723441 0,10909859 ! negative regulation of blood vessel endothelial cell migration GO:0043537 5 5 0,000 0,03723441 0,10892541 ! regulation of NF-kappaB import into nucleus GO:0042345 5 5 0,000 0,03723441 0,10875279 ! muscle adaptation GO:0043500 5 5 0,000 0,03723441 0,10858071 ! positive regulation of actin filament bundle formation GO:0032233 5 5 0,000 0,03723441 0,10840918 ! embryonic heart tube development GO:0035050 5 5 0,000 0,03723441 0,10823819 ! cardiac cell differentiation GO:0035051 6 5 0,000 0,03723441 0,10806773 ! positive regulation of homeostatic process GO:0032846 5 5 0,000 0,03723441 0,10789782 ! defense response to fungus GO:0050832 5 5 0,000 0,03723441 0,10772843 ! lysogeny GO:0030069 5 5 0,000 0,03723441 0,10755958 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 5 5 0,000 0,03723441 0,10739125 ! B cell receptor signaling pathway GO:0050853 5 5 0,000 0,03723441 0,10722345 ! positive regulation of smooth muscle contraction GO:0045987 5 5 0,000 0,03723441 0,10705618 ! response to nicotine GO:0035094 5 5 0,000 0,03723441 0,10688942 ! establishment of cell polarity GO:0030010 5 5 0,000 0,03723441 0,10672319 ! mitochondrion localization GO:0051646 5 5 0,000 0,03723441 0,10655747 ! nucleus localization GO:0051647 5 5 0,000 0,03723441 0,10639226 ! regulation of synapse structure and activity GO:0050803 5 5 0,000 0,03723441 0,10622757 ! cell cycle checkpoint GO:0000075 42 41 1,000 0,03808809 0,10849514 ! regulation of caspase activity GO:0043281 41 41 1,000 0,03808809 0,10832771 ! leukocyte mediated immunity GO:0002443 41 41 1,000 0,03808809 0,10816079 ! anti-apoptosis GO:0006916 100 99 2,000 0,03844448 0,1090049 ! response to hormone stimulus GO:0009725 102 100 2,000 0,03942721 0,11161959 ! muscle organ development GO:0007517 102 100 2,000 0,03942721 0,1114484 ! regulation of endopeptidase activity GO:0052548 42 42 1,000 0,03980258 0,11233715 ! protein ubiquitination GO:0016567 43 42 1,000 0,03980258 0,11216539 ! forebrain development GO:0030900 43 42 1,000 0,03980258 0,11199414 ! one-carbon metabolic process GO:0006730 42 42 1,000 0,03980258 0,11182342 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 42 42 1,000 0,03980258 0,11165321 ! humoral immune response GO:0006959 44 44 1,000 0,04331797 0,12132982 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 45 44 1,000 0,04331797 0,12114571 ! protein import into nucleus GO:0006606 44 44 1,000 0,04331797 0,12096216 ! negative regulation of organelle organization GO:0010639 45 44 1,000 0,04331797 0,12077916 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 6 6 0,000 0,04451642 0,12393316 ! axon extension GO:0048675 7 6 0,000 0,04451642 0,12374623 ! oligosaccharide biosynthetic process GO:0009312 6 6 0,000 0,04451642 0,12355987 ! tRNA modification GO:0006400 6 6 0,000 0,04451642 0,12337406 ! somatic diversification of immune receptors via somatic mutation GO:0002566 6 6 0,000 0,04451642 0,12318882 GO:0016446|somatic hypermutation of immunoglobulin genes, ! 'de novo' posttranslational protein folding GO:0051084 6 6 0,000 0,04451642 0,12300413 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 6 6 0,000 0,04451642 0,12281999 ! negative regulation of cellular catabolic process GO:0031330 6 6 0,000 0,04451642 0,1226364 ! regulation of S phase GO:0033261 6 6 0,000 0,04451642 0,12245336 ! myotube differentiation GO:0014902 6 6 0,000 0,04451642 0,12227087 ! regulation of B cell proliferation GO:0030888 6 6 0,000 0,04451642 0,12208892 ! bone remodeling GO:0046849 6 6 0,000 0,04451642 0,12190751 ! N-glycan processing GO:0006491 6 6 0,000 0,04451642 0,12172664 ! regulation of lipid kinase activity GO:0043550 6 6 0,000 0,04451642 0,1215463 ! glycosaminoglycan catabolic process GO:0006027 6 6 0,000 0,04451642 0,1213665 ! negative regulation of JAK-STAT cascade GO:0046426 6 6 0,000 0,04451642 0,12118723 ! retina development in camera-type eye GO:0060041 6 6 0,000 0,04451642 0,12100849 ! RNA methylation GO:0001510 6 6 0,000 0,04451642 0,12083027 ! cartilage condensation GO:0001502 7 6 0,000 0,04451642 0,12065258 ! regulation of activated T cell proliferation GO:0046006 6 6 0,000 0,04451642 0,12047541 ! succinate metabolic process GO:0006105 7 6 0,000 0,04451642 0,12029876 ! artery development GO:0060840 6 6 0,000 0,04451642 0,12012263 GO:0048844|artery morphogenesis, ! positive regulation of neurotransmitter transport GO:0051590 6 6 0,000 0,04451642 0,11994701 ! bile acid metabolic process GO:0008206 6 6 0,000 0,04451642 0,1197719 ! androgen metabolic process GO:0008209 6 6 0,000 0,04451642 0,11959731 ! estrogen metabolic process GO:0008210 6 6 0,000 0,04451642 0,11942322 ! limbic system development GO:0021761 7 6 0,000 0,04451642 0,11924964 ! positive regulation of transcription factor import into nucleus GO:0042993 6 6 0,000 0,04451642 0,11907656 ! positive regulation of heart contraction GO:0045823 6 6 0,000 0,04451642 0,11890399 ! positive regulation of gene expression, epigenetic GO:0045815 6 6 0,000 0,04451642 0,11873191 ! pathogenesis GO:0009405 6 6 0,000 0,04451642 0,11856034 ! negative regulation of protein amino acid phosphorylation GO:0001933 6 6 0,000 0,04451642 0,11838925 ! positive regulation of cell growth GO:0030307 6 6 0,000 0,04451642 0,11821866 ! ribonucleoside triphosphate catabolic process GO:0009203 6 6 0,000 0,04451642 0,11804857 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! regulation of chemokine biosynthetic process GO:0045073 6 6 0,000 0,04451642 0,11787896 ! nerve growth factor receptor signaling pathway GO:0048011 6 6 0,000 0,04451642 0,11770983 ! inositol phosphate-mediated signaling GO:0048016 6 6 0,000 0,04451642 0,11754119 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 6 6 0,000 0,04451642 0,11737304 ! arginine metabolic process GO:0006525 6 6 0,000 0,04451642 0,11720536 GO:0006527|arginine catabolic process, ! regulation of catecholamine secretion GO:0050433 6 6 0,000 0,04451642 0,11703816 ! oligodendrocyte differentiation GO:0048709 6 6 0,000 0,04451642 0,11687144 ! glutamate catabolic process GO:0006538 7 6 0,000 0,04451642 0,1167052 ! telomere maintenance via telomerase GO:0007004 6 6 0,000 0,04451642 0,11653942 GO:0010833|telomere maintenance via telomere lengthening, ! L-phenylalanine metabolic process GO:0006558 6 6 0,000 0,04451642 0,11637412 GO:0006559|L-phenylalanine catabolic process, ! glucan biosynthetic process GO:0009250 6 6 0,000 0,04451642 0,11620928 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 6 6 0,000 0,04451642 0,11604491 ! V(D)J recombination GO:0033151 6 6 0,000 0,04451642 0,11588101 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 0,04451642 0,11571756 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 6 6 0,000 0,04451642 0,11555458 ! negative regulation of endothelial cell migration GO:0010596 6 6 0,000 0,04451642 0,11539206 ! regulation of heart rate GO:0002027 6 6 0,000 0,04451642 0,11522999 ! lipid digestion GO:0044241 6 6 0,000 0,04451642 0,11506838 ! asymmetric protein localization GO:0008105 6 6 0,000 0,04451642 0,11490722 ! retrograde transport, endosome to Golgi GO:0042147 6 6 0,000 0,04451642 0,11474651 ! phagocytosis, engulfment GO:0006911 6 6 0,000 0,04451642 0,11458625 ! Rac protein signal transduction GO:0016601 6 6 0,000 0,04451642 0,11442643 ! regulation of calcium ion transport into cytosol GO:0010522 6 6 0,000 0,04451642 0,11426707 ! ruffle organization GO:0031529 6 6 0,000 0,04451642 0,11410814 ! preassembly of GPI anchor in ER membrane GO:0016254 6 6 0,000 0,04451642 0,11394966 ! retinoic acid metabolic process GO:0042573 6 6 0,000 0,04451642 0,11379161 ! neutral amino acid transport GO:0015804 6 6 0,000 0,04451642 0,11363401 ! bone mineralization GO:0030282 6 6 0,000 0,04451642 0,11347684 GO:0031214|biomineral formation, ! rRNA modification GO:0000154 6 6 0,000 0,04451642 0,1133201 ! negative regulation of ossification GO:0030279 6 6 0,000 0,04451642 0,1131638 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 6 6 0,000 0,04451642 0,11300792 GO:0002717|positive regulation of natural killer cell mediated immunity, GO:0002715|regulation of natural killer cell mediated immunity, GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 7 6 0,000 0,04451642 0,11285248 ! purine base biosynthetic process GO:0009113 6 6 0,000 0,04451642 0,11269746 ! negative regulation of axonogenesis GO:0050771 7 6 0,000 0,04451642 0,11254287 ! regulation of phagocytosis GO:0050764 6 6 0,000 0,04451642 0,1123887 ! regulation of organ growth GO:0046620 6 6 0,000 0,04451642 0,11223496 ! regulation of circadian rhythm GO:0042752 6 6 0,000 0,04451642 0,11208163 ! positive regulation of T cell mediated immunity GO:0002711 6 6 0,000 0,04451642 0,11192872 ! response to dsRNA GO:0043331 6 6 0,000 0,04451642 0,11177623 ! DNA unwinding during replication GO:0006268 6 6 0,000 0,04451642 0,11162415 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 6 6 0,000 0,04451642 0,11147249 GO:0009147|pyrimidine nucleoside triphosphate metabolic process, ! genitalia development GO:0048806 6 6 0,000 0,04451642 0,11132124 ! sphingomyelin metabolic process GO:0006684 6 6 0,000 0,04451642 0,1111704 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 6 6 0,000 0,04451642 0,11101996 ! positive regulation of B cell differentiation GO:0045579 6 6 0,000 0,04451642 0,11086994 ! multicellular organismal aging GO:0010259 6 6 0,000 0,04451642 0,11072031 ! regulation of focal adhesion formation GO:0051893 7 6 0,000 0,04451642 0,1105711 ! respiratory chain complex IV assembly GO:0008535 6 6 0,000 0,04451642 0,11042228 ! erythrocyte development GO:0048821 6 6 0,000 0,04451642 0,11027386 ! renal water homeostasis GO:0003091 6 6 0,000 0,04451642 0,11012584 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 6 6 0,000 0,04451642 0,10997822 GO:0043372|positive regulation of CD4-positive, alpha beta T cell differentiation, ! ribosomal large subunit biogenesis GO:0042273 6 6 0,000 0,04451642 0,10983099 ! regulation of Rho GTPase activity GO:0032319 6 6 0,000 0,04451642 0,10968416 ! ribosome assembly GO:0042255 6 6 0,000 0,04451642 0,10953772 ! positive regulation of Ras GTPase activity GO:0032320 6 6 0,000 0,04451642 0,10939167 ! diencephalon development GO:0021536 6 6 0,000 0,04451642 0,10924601 ! fucose catabolic process GO:0019317 6 6 0,000 0,04451642 0,10910074 GO:0042355|L-fucose catabolic process, ! protein sumoylation GO:0016925 6 6 0,000 0,04451642 0,10895585 ! regulation of lipid transport GO:0032368 6 6 0,000 0,04451642 0,10881134 ! regulation of cell division GO:0051302 6 6 0,000 0,04451642 0,10866722 ! positive regulation of interleukin-1 secretion GO:0050716 6 6 0,000 0,04451642 0,10852348 ! cellular metabolic compound salvage GO:0043094 6 6 0,000 0,04451642 0,10838012 ! regulation of T-helper 2 type immune response GO:0002828 6 6 0,000 0,04451642 0,10823714 ! salivary gland morphogenesis GO:0007435 6 6 0,000 0,04451642 0,10809454 ! neuroblast proliferation GO:0007405 6 6 0,000 0,04451642 0,10795231 ! regulation of interleukin-1 beta secretion GO:0050706 6 6 0,000 0,04451642 0,10781045 ! nitric oxide mediated signal transduction GO:0007263 6 6 0,000 0,04451642 0,10766897 ! regulation of glucose transport GO:0010827 6 6 0,000 0,04451642 0,10752785 GO:0046324|regulation of glucose import, ! intestinal absorption GO:0050892 6 6 0,000 0,04451642 0,10738711 ! methionine biosynthetic process GO:0009086 6 6 0,000 0,04451642 0,10724674 ! glutamine family amino acid biosynthetic process GO:0009084 6 6 0,000 0,04451642 0,10710673 ! serine family amino acid biosynthetic process GO:0009070 6 6 0,000 0,04451642 0,10696708 ! thymus development GO:0048538 6 6 0,000 0,04451642 0,1068278 ! lymph node development GO:0048535 6 6 0,000 0,04451642 0,10668889 ! organic cation transport GO:0015695 6 6 0,000 0,04451642 0,10655033 ! negative regulation of BMP signaling pathway GO:0030514 6 6 0,000 0,04451642 0,10641213 ! regulation of RNA splicing GO:0043484 6 6 0,000 0,04451642 0,10627429 ! positive regulation of JNK cascade GO:0046330 7 6 0,000 0,04451642 0,10613681 ! sperm-egg recognition GO:0035036 7 6 0,000 0,04451642 0,10599968 GO:0007339|binding of sperm to zona pellucida, ! germ cell migration GO:0008354 6 6 0,000 0,04451642 0,10586291 ! establishment or maintenance of apical/basal cell polarity GO:0035088 6 6 0,000 0,04451642 0,10572649 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 6 6 0,000 0,04451642 0,10559042 ! alditol metabolic process GO:0019400 6 6 0,000 0,04451642 0,1054547 ! regulation of synaptic transmission, GABAergic GO:0032228 6 6 0,000 0,04451642 0,10531932 ! regulation of amino acid transport GO:0051955 6 6 0,000 0,04451642 0,1051843 ! maternal placenta development GO:0001893 6 6 0,000 0,04451642 0,10504962 ! negative regulation of immune effector process GO:0002698 6 6 0,000 0,04451642 0,10491529 ! amine biosynthetic process GO:0009309 46 45 1,000 0,04511784 0,10619691 ! homophilic cell adhesion GO:0007156 45 45 1,000 0,04511784 0,10606146 ! phosphoinositide-mediated signaling GO:0048015 45 45 1,000 0,04511784 0,10592635 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 46 45 1,000 0,04511784 0,10579158 ! nuclear import GO:0051170 45 45 1,000 0,04511784 0,10565716 ! protein processing GO:0016485 45 45 1,000 0,04511784 0,10552307 ! tube morphogenesis GO:0035239 47 46 1,000 0,04694515 0,10965768 ! regulation of peptidase activity GO:0052547 46 46 1,000 0,04694515 0,10951888 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 47 46 1,000 0,04694515 0,10938042 ! positive regulation of ligase activity GO:0051351 47 46 1,000 0,04694515 0,10924231 ! regulation of membrane potential GO:0042391 46 46 1,000 0,04694515 0,10910455 ! sex differentiation GO:0007548 47 47 1,000 0,0487994 0,11327115 ! amine transport GO:0015837 47 47 1,000 0,0487994 0,11312867 ! actin filament organization GO:0007015 50 48 1,000 0,0506801 0,11734098 ! regulation of ubiquitin-protein ligase activity GO:0051438 49 48 1,000 0,0506801 0,11719375 ! protein localization in nucleus GO:0034504 48 48 1,000 0,0506801 0,11704689 ! respiratory burst GO:0045730 7 7 0,000 0,0517444 0,11935535 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 7 7 0,000 0,0517444 0,11920615 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 7 7 0,000 0,0517444 0,11905733 ! negative regulation of cell projection organization GO:0031345 8 7 0,000 0,0517444 0,11890888 ! positive regulation of blood pressure GO:0045777 7 7 0,000 0,0517444 0,1187608 ! pteridine and derivative biosynthetic process GO:0042559 7 7 0,000 0,0517444 0,11861309 ! double-strand break repair via homologous recombination GO:0000724 7 7 0,000 0,0517444 0,11846574 GO:0000725|recombinational repair, ! positive regulation of GTPase activity GO:0043547 7 7 0,000 0,0517444 0,11831876 ! SMAD protein nuclear translocation GO:0007184 7 7 0,000 0,0517444 0,11817215 ! cellular protein complex disassembly GO:0043624 8 7 0,000 0,0517444 0,1180259 GO:0043241|protein complex disassembly, ! hair follicle morphogenesis GO:0031069 7 7 0,000 0,0517444 0,11788 ! gene silencing by RNA GO:0031047 7 7 0,000 0,0517444 0,11773447 ! regulation of receptor-mediated endocytosis GO:0048259 7 7 0,000 0,0517444 0,1175893 ! oxaloacetate metabolic process GO:0006107 7 7 0,000 0,0517444 0,11744449 ! regulation of neurotransmitter transport GO:0051588 7 7 0,000 0,0517444 0,11730003 ! keratinocyte proliferation GO:0043616 7 7 0,000 0,0517444 0,11715593 ! negative regulation of muscle cell differentiation GO:0051148 7 7 0,000 0,0517444 0,11701218 ! visual behavior GO:0007632 7 7 0,000 0,0517444 0,11686878 GO:0008542|visual learning, ! startle response GO:0001964 7 7 0,000 0,0517444 0,11672573 ! amyloid precursor protein metabolic process GO:0042982 7 7 0,000 0,0517444 0,11658304 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 8 7 0,000 0,0517444 0,11644069 ! positive regulation of lipid metabolic process GO:0045834 7 7 0,000 0,0517444 0,11629869 ! negative regulation of lipid metabolic process GO:0045833 7 7 0,000 0,0517444 0,11615703 ! regulation of interferon-gamma biosynthetic process GO:0045072 7 7 0,000 0,0517444 0,11601572 ! endothelial cell differentiation GO:0045446 7 7 0,000 0,0517444 0,11587475 ! negative regulation of striated muscle development GO:0045843 7 7 0,000 0,0517444 0,11573413 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 7 7 0,000 0,0517444 0,11559385 ! digestive system development GO:0055123 7 7 0,000 0,0517444 0,1154539 GO:0048546|digestive tract morphogenesis, GO:0048547|gut morphogenesis, ! regulation of exit from mitosis GO:0007096 7 7 0,000 0,0517444 0,1153143 ! protein targeting to ER GO:0045047 8 7 0,000 0,0517444 0,11517503 ! cell differentiation in spinal cord GO:0021515 7 7 0,000 0,0517444 0,1150361 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 7 7 0,000 0,0517444 0,1148975 ! endoderm development GO:0007492 7 7 0,000 0,0517444 0,11475923 ! regulation of defense response to virus GO:0050688 7 7 0,000 0,0517444 0,1146213 ! glycolipid biosynthetic process GO:0009247 7 7 0,000 0,0517444 0,1144837 GO:0006688|glycosphingolipid biosynthetic process, ! response to hexose stimulus GO:0009746 7 7 0,000 0,0517444 0,11434643 GO:0034284|response to monosaccharide stimulus, GO:0009749|response to glucose stimulus, ! membrane protein ectodomain proteolysis GO:0006509 7 7 0,000 0,0517444 0,11420949 GO:0033619|membrane protein proteolysis, ! positive regulation of survival gene product expression GO:0045885 7 7 0,000 0,0517444 0,11407287 ! regulation of skeletal muscle fiber development GO:0048742 7 7 0,000 0,0517444 0,11393659 ! cardiac muscle tissue development GO:0048738 7 7 0,000 0,0517444 0,11380062 ! nucleotide-sugar metabolic process GO:0009225 7 7 0,000 0,0517444 0,11366499 ! complement activation, alternative pathway GO:0006957 7 7 0,000 0,0517444 0,11352967 ! arachidonic acid secretion GO:0050482 7 7 0,000 0,0517444 0,11339468 GO:0032309|icosanoid secretion, ! polyamine biosynthetic process GO:0006596 7 7 0,000 0,0517444 0,11326 ! UV protection GO:0009650 7 7 0,000 0,0517444 0,11312565 ! DNA integration GO:0015074 7 7 0,000 0,0517444 0,11299162 ! myofibril assembly GO:0030239 7 7 0,000 0,0517444 0,1128579 GO:0055002|striated muscle cell development, ! positive regulation of muscle contraction GO:0045933 7 7 0,000 0,0517444 0,1127245 ! negative regulation of muscle contraction GO:0045932 7 7 0,000 0,0517444 0,11259141 ! chondroitin sulfate biosynthetic process GO:0030206 7 7 0,000 0,0517444 0,11245864 GO:0030204|chondroitin sulfate metabolic process, ! regulation of exocytosis GO:0017157 8 7 0,000 0,0517444 0,11232618 ! phosphatidylcholine biosynthetic process GO:0006656 7 7 0,000 0,0517444 0,11219403 ! heparan sulfate proteoglycan metabolic process GO:0030201 7 7 0,000 0,0517444 0,11206219 GO:0015012|heparan sulfate proteoglycan biosynthetic process, ! stem cell development GO:0048864 7 7 0,000 0,0517444 0,11193066 GO:0019827|stem cell maintenance, ! alpha-beta T cell differentiation GO:0046632 7 7 0,000 0,0517444 0,11179944 ! negative regulation of myeloid leukocyte differentiation GO:0002762 7 7 0,000 0,0517444 0,11166853 ! NLS-bearing substrate import into nucleus GO:0006607 7 7 0,000 0,0517444 0,11153792 ! axon cargo transport GO:0008088 7 7 0,000 0,0517444 0,11140762 ! eating behavior GO:0042755 7 7 0,000 0,0517444 0,11127762 ! RNA-dependent DNA replication GO:0006278 7 7 0,000 0,0517444 0,11114793 ! purine nucleoside triphosphate catabolic process GO:0009146 7 7 0,000 0,0517444 0,11101854 ! regulation of interleukin-8 production GO:0032677 7 7 0,000 0,0517444 0,11088945 ! purine ribonucleotide catabolic process GO:0009154 7 7 0,000 0,0517444 0,11076065 ! ribosomal small subunit biogenesis GO:0042274 7 7 0,000 0,0517444 0,11063216 ! cranial nerve development GO:0021545 7 7 0,000 0,0517444 0,11050397 ! protein import into peroxisome matrix GO:0016558 7 7 0,000 0,0517444 0,11037607 ! induction of an organ GO:0001759 7 7 0,000 0,0517444 0,11024847 ! leukocyte activation during immune response GO:0002366 7 7 0,000 0,0517444 0,11012116 GO:0002263|cell activation during immune response, ! response to estradiol stimulus GO:0032355 7 7 0,000 0,0517444 0,10999414 ! autonomic nervous system development GO:0048483 7 7 0,000 0,0517444 0,10986742 ! intracellular lipid transport GO:0032365 7 7 0,000 0,0517444 0,10974099 ! detection of chemical stimulus GO:0009593 8 7 0,000 0,0517444 0,10961485 ! negative regulation of cytokine secretion GO:0050710 7 7 0,000 0,0517444 0,109489 ! regulation of interleukin-1 secretion GO:0050704 7 7 0,000 0,0517444 0,10936344 ! natural killer cell activation GO:0030101 7 7 0,000 0,0517444 0,10923817 ! NADP metabolic process GO:0006739 7 7 0,000 0,0517444 0,10911318 ! neuromuscular synaptic transmission GO:0007274 7 7 0,000 0,0517444 0,10898848 ! ubiquinone metabolic process GO:0006743 7 7 0,000 0,0517444 0,10886407 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, GO:0042375|quinone cofactor metabolic process, ! regulation of macrophage differentiation GO:0045649 8 7 0,000 0,0517444 0,10873994 ! positive regulation of acute inflammatory response GO:0002675 7 7 0,000 0,0517444 0,10861609 ! regulation of osteoclast differentiation GO:0045670 7 7 0,000 0,0517444 0,10849252 ! negative regulation of cell-substrate adhesion GO:0010812 8 7 0,000 0,0517444 0,10836923 GO:0001953|negative regulation of cell-matrix adhesion, ! multicellular organismal water homeostasis GO:0050891 7 7 0,000 0,0517444 0,10824622 ! regulation of ATPase activity GO:0043462 7 7 0,000 0,0517444 0,1081235 ! cell-cell recognition GO:0009988 8 7 0,000 0,0517444 0,10800105 ! hormone catabolic process GO:0042447 7 7 0,000 0,0517444 0,10787887 ! dopamine metabolic process GO:0042417 7 7 0,000 0,0517444 0,10775698 ! cAMP biosynthetic process GO:0006171 7 7 0,000 0,0517444 0,10763535 ! oxygen transport GO:0015671 7 7 0,000 0,0517444 0,10751401 ! pyridine nucleotide biosynthetic process GO:0019363 7 7 0,000 0,0517444 0,10739293 ! biogenic amine catabolic process GO:0042402 7 7 0,000 0,0517444 0,10727213 ! regulation of axon extension GO:0030516 7 7 0,000 0,0517444 0,1071516 ! cell killing GO:0001906 7 7 0,000 0,0517444 0,10703134 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 7 7 0,000 0,0517444 0,10691135 ! adult feeding behavior GO:0008343 7 7 0,000 0,0517444 0,10679163 ! pyrimidine nucleotide catabolic process GO:0006244 7 7 0,000 0,0517444 0,10667217 ! positive regulation of protein polymerization GO:0032273 7 7 0,000 0,0517444 0,10655299 ! T cell receptor signaling pathway GO:0050852 7 7 0,000 0,0517444 0,10643407 ! response to cold GO:0009409 7 7 0,000 0,0517444 0,10631541 ! leukocyte differentiation GO:0002521 50 49 1,000 0,05258675 0,10792581 ! ossification GO:0001503 50 49 1,000 0,05258675 0,10780576 GO:0060348|bone development, ! response to nutrient GO:0007584 49 49 1,000 0,05258675 0,10768598 ! regulation of ligase activity GO:0051340 50 49 1,000 0,05258675 0,10756646 ! regulation of neurogenesis GO:0050767 51 50 1,000 0,05451888 0,11139501 ! chromatin assembly GO:0031497 50 50 1,000 0,05451888 0,11127164 GO:0006334|nucleosome assembly, ! T cell activation GO:0042110 51 50 1,000 0,05451888 0,11114856 ! anterior/posterior pattern formation GO:0009952 51 50 1,000 0,05451888 0,11102574 ! biogenic amine metabolic process GO:0006576 52 51 1,000 0,05647601 0,11488442 ! protein modification by small protein conjugation GO:0032446 52 51 1,000 0,05647601 0,11475775 ! positive regulation of immune response GO:0050778 51 51 1,000 0,05647601 0,11463137 ! protein-DNA complex assembly GO:0065004 51 51 1,000 0,05647601 0,11450526 ! protein maturation GO:0051604 51 51 1,000 0,05647601 0,11437943 ! cell fate commitment GO:0045165 52 52 1,000 0,05845766 0,11826286 ! regulation of body fluid levels GO:0050878 55 52 1,000 0,05845766 0,11813319 ! regulation of skeletal muscle tissue development GO:0048641 8 8 0,000 0,05891874 0,11893455 ! negative regulation of muscle development GO:0048635 8 8 0,000 0,05891874 0,11880443 ! very-long-chain fatty acid metabolic process GO:0000038 8 8 0,000 0,05891874 0,11867459 ! positive regulation of cell killing GO:0031343 8 8 0,000 0,05891874 0,11854503 ! superoxide anion generation GO:0042554 8 8 0,000 0,05891874 0,11841575 ! sulfur amino acid biosynthetic process GO:0000097 8 8 0,000 0,05891874 0,11828676 ! cGMP metabolic process GO:0046068 8 8 0,000 0,05891874 0,11815805 GO:0006182|cGMP biosynthetic process, ! thyroid gland development GO:0030878 8 8 0,000 0,05891874 0,11802962 ! 'de novo' protein folding GO:0006458 8 8 0,000 0,05891874 0,11790146 ! dicarboxylic acid transport GO:0006835 8 8 0,000 0,05891874 0,11777359 ! phosphoinositide phosphorylation GO:0046854 8 8 0,000 0,05891874 0,11764599 ! embryonic hindlimb morphogenesis GO:0035116 8 8 0,000 0,05891874 0,11751866 ! zinc ion transport GO:0006829 8 8 0,000 0,05891874 0,11739162 ! embryonic forelimb morphogenesis GO:0035115 8 8 0,000 0,05891874 0,11726484 ! folic acid and derivative biosynthetic process GO:0009396 8 8 0,000 0,05891874 0,11713835 ! regulation of neuronal synaptic plasticity GO:0048168 8 8 0,000 0,05891874 0,11701212 ! cardiac muscle contraction GO:0060048 8 8 0,000 0,05891874 0,11688616 ! lipid localization GO:0010876 8 8 0,000 0,05891874 0,11676048 GO:0019915|lipid storage, ! response to pain GO:0048265 8 8 0,000 0,05891874 0,11663507 ! response to cAMP GO:0051591 8 8 0,000 0,05891874 0,11650992 ! COPI coating of Golgi vesicle GO:0048205 8 8 0,000 0,05891874 0,11638504 GO:0048200|Golgi transport vesicle coating, ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 8 0,000 0,05891874 0,11626043 ! negative regulation of ion transport GO:0043271 8 8 0,000 0,05891874 0,11613609 ! regulation of response to extracellular stimulus GO:0032104 8 8 0,000 0,05891874 0,11601201 GO:0032107|regulation of response to nutrient levels, ! adult walking behavior GO:0007628 8 8 0,000 0,05891874 0,1158882 ! sensory perception of taste GO:0050909 8 8 0,000 0,05891874 0,11576465 ! organelle fusion GO:0048284 8 8 0,000 0,05891874 0,11564137 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 8 8 0,000 0,05891874 0,11551835 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! T cell selection GO:0045058 8 8 0,000 0,05891874 0,11539559 ! negative regulation of proteolysis GO:0045861 8 8 0,000 0,05891874 0,11527308 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 8 8 0,000 0,05891874 0,11515084 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 8 8 0,000 0,05891874 0,11502886 ! sperm motility GO:0030317 8 8 0,000 0,05891874 0,11490714 ! regulation of striated muscle contraction GO:0006942 8 8 0,000 0,05891874 0,11478567 ! DNA duplex unwinding GO:0032508 8 8 0,000 0,05891874 0,11466446 GO:0032392|DNA geometric change, ! glycine metabolic process GO:0006544 8 8 0,000 0,05891874 0,11454351 ! ribonucleotide catabolic process GO:0009261 8 8 0,000 0,05891874 0,11442281 ! negative regulation of microtubule depolymerization GO:0007026 8 8 0,000 0,05891874 0,11430236 GO:0031114|regulation of microtubule depolymerization, ! phosphagen metabolic process GO:0006599 8 8 0,000 0,05891874 0,11418217 GO:0006600|creatine metabolic process, ! polyamine metabolic process GO:0006595 8 8 0,000 0,05891874 0,11406223 ! Golgi organization GO:0007030 8 8 0,000 0,05891874 0,11394255 ! regulation of stress fiber formation GO:0051492 9 8 0,000 0,05891874 0,11382311 ! fructose metabolic process GO:0006000 8 8 0,000 0,05891874 0,11370392 ! mannose metabolic process GO:0006013 9 8 0,000 0,05891874 0,11358499 ! NAD metabolic process GO:0019674 8 8 0,000 0,05891874 0,1134663 ! negative regulation of mitotic cell cycle GO:0045930 9 8 0,000 0,05891874 0,11334786 ! response to fungus GO:0009620 8 8 0,000 0,05891874 0,11322966 ! stem cell differentiation GO:0048863 8 8 0,000 0,05891874 0,11311171 ! alpha-beta T cell activation GO:0046631 8 8 0,000 0,05891874 0,11299401 ! positive regulation of myeloid leukocyte differentiation GO:0002763 9 8 0,000 0,05891874 0,11287656 ! embryonic digit morphogenesis GO:0042733 8 8 0,000 0,05891874 0,11275934 ! regulation of cytokine production during immune response GO:0002718 8 8 0,000 0,05891874 0,11264237 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 0,05891874 0,11252564 ! regulation of vasodilation GO:0042312 8 8 0,000 0,05891874 0,11240916 ! vasoconstriction GO:0042310 8 8 0,000 0,05891874 0,11229291 ! regulation of T cell mediated immunity GO:0002709 8 8 0,000 0,05891874 0,11217691 ! muscle cell development GO:0055001 8 8 0,000 0,05891874 0,11206114 ! nucleoside triphosphate catabolic process GO:0009143 8 8 0,000 0,05891874 0,11194561 ! regulation of fatty acid metabolic process GO:0019217 8 8 0,000 0,05891874 0,11183033 ! sensory perception of pain GO:0019233 8 8 0,000 0,05891874 0,11171527 ! gastrulation with mouth forming second GO:0001702 8 8 0,000 0,05891874 0,11160046 ! immunoglobulin production during immune response GO:0002381 8 8 0,000 0,05891874 0,11148588 GO:0002208|somatic diversification of immunoglobulins during immune response, GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! mRNA cleavage GO:0006379 8 8 0,000 0,05891874 0,11137153 ! chromatin silencing GO:0006342 8 8 0,000 0,05891874 0,11125742 ! tissue regeneration GO:0042246 8 8 0,000 0,05891874 0,11114355 ! salivary gland development GO:0007431 8 8 0,000 0,05891874 0,1110299 ! negative regulation of blood coagulation GO:0030195 9 8 0,000 0,05891874 0,11091649 ! T cell homeostasis GO:0043029 8 8 0,000 0,05891874 0,11080331 ! peptide biosynthetic process GO:0043043 9 8 0,000 0,05891874 0,11069036 ! water homeostasis GO:0030104 8 8 0,000 0,05891874 0,11057764 ! cofactor transport GO:0051181 8 8 0,000 0,05891874 0,11046515 ! regulation of acute inflammatory response GO:0002673 8 8 0,000 0,05891874 0,11035289 ! acid secretion GO:0046717 8 8 0,000 0,05891874 0,11024086 ! C21-steroid hormone biosynthetic process GO:0006700 8 8 0,000 0,05891874 0,11012905 ! protein-chromophore linkage GO:0018298 9 8 0,000 0,05891874 0,11001747 ! regulation of immunoglobulin production GO:0002637 8 8 0,000 0,05891874 0,10990612 ! branched chain family amino acid metabolic process GO:0009081 8 8 0,000 0,05891874 0,10979499 ! catecholamine biosynthetic process GO:0042423 8 8 0,000 0,05891874 0,10968409 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 8 8 0,000 0,05891874 0,10957341 ! aromatic compound biosynthetic process GO:0019438 8 8 0,000 0,05891874 0,10946295 ! regulation of organic acid transport GO:0032890 8 8 0,000 0,05891874 0,10935271 ! positive regulation of calcium ion transport GO:0051928 8 8 0,000 0,05891874 0,1092427 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 8 8 0,000 0,05891874 0,10913291 ! regulation of multi-organism process GO:0043900 8 8 0,000 0,05891874 0,10902334 ! positive regulation of amine transport GO:0051954 8 8 0,000 0,05891874 0,10891399 ! developmental induction GO:0031128 8 8 0,000 0,05891874 0,10880486 GO:0045168|cell-cell signaling involved in cell fate specification, ! peptide hormone secretion GO:0030072 8 8 0,000 0,05891874 0,10869594 ! positive regulation of calcium-mediated signaling GO:0050850 8 8 0,000 0,05891874 0,10858725 ! actin filament polymerization GO:0030041 9 8 0,000 0,05891874 0,10847877 ! peptide hormone processing GO:0016486 8 8 0,000 0,05891874 0,1083705 ! positive regulation of synaptic transmission GO:0050806 8 8 0,000 0,05891874 0,10826246 ! regulation of steroid biosynthetic process GO:0050810 8 8 0,000 0,05891874 0,10815463 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 53 53 1,000 0,06046338 0,1108796 ! regulation of T cell activation GO:0050863 53 53 1,000 0,06046338 0,11076938 ! protein amino acid dephosphorylation GO:0006470 55 54 1,000 0,06249269 0,11437341 ! negative regulation of multicellular organismal process GO:0051241 55 54 1,000 0,06249269 0,11425995 ! nucleosome organization GO:0034728 55 55 1,000 0,06454515 0,11789564 ! microtubule cytoskeleton organization GO:0000226 55 55 1,000 0,06454515 0,11777892 ! protein modification by small protein conjugation or removal GO:0070647 56 55 1,000 0,06454515 0,11766242 ! lactation GO:0007595 10 9 0,000 0,06603985 0,12026822 ! embryonic pattern specification GO:0009880 10 9 0,000 0,06603985 0,1201495 ! positive regulation of cell projection organization GO:0031346 9 9 0,000 0,06603985 0,12003101 ! regulation of membrane protein ectodomain proteolysis GO:0051043 9 9 0,000 0,06603985 0,11991275 ! positive regulation of protein complex assembly GO:0031334 9 9 0,000 0,06603985 0,11979472 ! cortical actin cytoskeleton organization GO:0030866 10 9 0,000 0,06603985 0,11967693 ! viral genome replication GO:0019079 9 9 0,000 0,06603985 0,11955937 ! phospholipid catabolic process GO:0009395 9 9 0,000 0,06603985 0,11944204 ! copper ion transport GO:0006825 9 9 0,000 0,06603985 0,11932494 ! lipid phosphorylation GO:0046834 9 9 0,000 0,06603985 0,11920807 ! aminoglycan catabolic process GO:0006026 9 9 0,000 0,06603985 0,11909143 ! Golgi vesicle budding GO:0048194 9 9 0,000 0,06603985 0,11897501 ! regulation of cell-cell adhesion GO:0022407 9 9 0,000 0,06603985 0,11885883 ! RNA polyadenylation GO:0043631 9 9 0,000 0,06603985 0,11874287 GO:0006378|mRNA polyadenylation, ! gamma-aminobutyric acid signaling pathway GO:0007214 9 9 0,000 0,06603985 0,11862713 ! regulation of postsynaptic membrane potential GO:0060078 9 9 0,000 0,06603985 0,11851163 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 9 9 0,000 0,06603985 0,11839634 ! negative regulation of cytokine biosynthetic process GO:0042036 9 9 0,000 0,06603985 0,11828128 ! phospholipid efflux GO:0033700 9 9 0,000 0,06603985 0,11816645 ! response to alkaloid GO:0043279 10 9 0,000 0,06603985 0,11805183 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 9 9 0,000 0,06603985 0,11793744 ! cytokine biosynthetic process GO:0042089 9 9 0,000 0,06603985 0,11782327 GO:0042107|cytokine metabolic process, ! negative regulation of gene expression, epigenetic GO:0045814 9 9 0,000 0,06603985 0,11770932 ! regulation of interleukin-2 biosynthetic process GO:0045076 9 9 0,000 0,06603985 0,11759559 ! response to ethanol GO:0045471 9 9 0,000 0,06603985 0,11748209 ! pyrimidine ribonucleotide metabolic process GO:0009218 9 9 0,000 0,06603985 0,11736879 ! activation of pro-apoptotic gene products GO:0008633 9 9 0,000 0,06603985 0,11725572 ! methionine metabolic process GO:0006555 9 9 0,000 0,06603985 0,11714287 ! glutamine metabolic process GO:0006541 9 9 0,000 0,06603985 0,11703023 ! cerebral cortex development GO:0021987 9 9 0,000 0,06603985 0,11691781 ! response to osmotic stress GO:0006970 9 9 0,000 0,06603985 0,1168056 ! pigmentation during development GO:0048066 9 9 0,000 0,06603985 0,11669361 ! reverse cholesterol transport GO:0043691 9 9 0,000 0,06603985 0,11658184 ! central nervous system neuron development GO:0021954 10 9 0,000 0,06603985 0,11647028 ! pyrimidine ribonucleoside metabolic process GO:0046131 9 9 0,000 0,06603985 0,11635893 ! nucleobase biosynthetic process GO:0046112 9 9 0,000 0,06603985 0,11624779 ! substrate-bound cell migration GO:0006929 9 9 0,000 0,06603985 0,11613687 ! neurotransmitter metabolic process GO:0042133 11 9 0,000 0,06603985 0,11602616 ! negative regulation of caspase activity GO:0043154 9 9 0,000 0,06603985 0,11591566 ! branching involved in ureteric bud morphogenesis GO:0001658 9 9 0,000 0,06603985 0,11580537 GO:0060675|ureteric bud morphogenesis, ! peptide secretion GO:0002790 9 9 0,000 0,06603985 0,11569529 ! regulation of dephosphorylation GO:0035303 9 9 0,000 0,06603985 0,11558541 ! cotranslational protein targeting to membrane GO:0006613 10 9 0,000 0,06603985 0,11547575 ! positive regulation of alpha-beta T cell differentiation GO:0046638 9 9 0,000 0,06603985 0,11536629 ! ventricular cardiac muscle morphogenesis GO:0055010 9 9 0,000 0,06603985 0,11525705 ! behavioral interaction between organisms GO:0051705 9 9 0,000 0,06603985 0,115148 ! positive regulation of protein import into nucleus GO:0042307 9 9 0,000 0,06603985 0,11503917 ! DNA replication initiation GO:0006270 9 9 0,000 0,06603985 0,11493054 ! prostaglandin metabolic process GO:0006693 9 9 0,000 0,06603985 0,11482211 GO:0006692|prostanoid metabolic process, ! T cell differentiation in the thymus GO:0033077 9 9 0,000 0,06603985 0,11471389 ! DNA fragmentation involved in apoptosis GO:0006309 9 9 0,000 0,06603985 0,11460588 ! regulation of immunoglobulin mediated immune response GO:0002889 9 9 0,000 0,06603985 0,11449806 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 10 9 0,000 0,06603985 0,11439045 ! positive regulation of cytokine secretion GO:0050715 9 9 0,000 0,06603985 0,11428304 ! negative regulation of inflammatory response GO:0050728 9 9 0,000 0,06603985 0,11417584 ! negative regulation of protein secretion GO:0050709 9 9 0,000 0,06603985 0,11406883 ! positive regulation of transmission of nerve impulse GO:0051971 9 9 0,000 0,06603985 0,11396202 ! collagen catabolic process GO:0030574 9 9 0,000 0,06603985 0,11385542 ! aromatic amino acid family catabolic process GO:0009074 9 9 0,000 0,06603985 0,11374901 ! purine base metabolic process GO:0006144 9 9 0,000 0,06603985 0,1136428 ! gas transport GO:0015669 9 9 0,000 0,06603985 0,11353679 ! cholesterol efflux GO:0033344 9 9 0,000 0,06603985 0,11343098 ! regulation of leukocyte mediated cytotoxicity GO:0001910 9 9 0,000 0,06603985 0,11332536 ! estrogen receptor signaling pathway GO:0030520 9 9 0,000 0,06603985 0,11321994 ! somatic recombination of immunoglobulin gene segments GO:0016447 9 9 0,000 0,06603985 0,11311472 ! regulation of actin filament bundle formation GO:0032231 10 9 0,000 0,06603985 0,11300969 ! defense response to virus GO:0051607 9 9 0,000 0,06603985 0,11290486 ! regulation of calcium-mediated signaling GO:0050848 9 9 0,000 0,06603985 0,11280022 ! actin filament-based movement GO:0030048 9 9 0,000 0,06603985 0,11269578 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 9 9 0,000 0,06603985 0,11259153 ! extracellular structure organization GO:0043062 56 56 1,000 0,0666203 0,11347616 ! regulation of nervous system development GO:0051960 57 56 1,000 0,0666203 0,11337138 ! innate immune response GO:0045087 58 58 1,000 0,07083691 0,12043581 ! dephosphorylation GO:0016311 60 59 1,000 0,07297749 0,12396084 ! carboxylic acid transport GO:0046942 59 59 1,000 0,07297749 0,1238467 GO:0015849|organic acid transport, ! regulation of cell development GO:0060284 60 59 1,000 0,07297749 0,12373276 ! cellular aromatic compound metabolic process GO:0006725 60 59 1,000 0,07297749 0,12361904 ! protein localization in organelle GO:0033365 59 59 1,000 0,07297749 0,12350552 ! immune effector process GO:0002252 59 59 1,000 0,07297749 0,12339222 ! protein import into nucleus, docking GO:0000059 10 10 0,000 0,0731081 0,12349974 ! regulation of protein ubiquitination GO:0031396 10 10 0,000 0,0731081 0,12338665 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 10 10 0,000 0,0731081 0,12327376 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 10 10 0,000 0,0731081 0,12316108 ! ER-associated protein catabolic process GO:0030433 10 10 0,000 0,0731081 0,1230486 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of cell killing GO:0031341 10 10 0,000 0,0731081 0,12293633 ! neuron maturation GO:0042551 10 10 0,000 0,0731081 0,12282427 ! pteridine and derivative metabolic process GO:0042558 10 10 0,000 0,0731081 0,1227124 ! positive regulation of anti-apoptosis GO:0045768 10 10 0,000 0,0731081 0,12260075 GO:0045767|regulation of anti-apoptosis, ! cortical cytoskeleton organization GO:0030865 11 10 0,000 0,0731081 0,12248929 ! regulation of lipid biosynthetic process GO:0046890 10 10 0,000 0,0731081 0,12237804 ! reciprocal meiotic recombination GO:0007131 10 10 0,000 0,0731081 0,12226699 ! hormone secretion GO:0046879 10 10 0,000 0,0731081 0,12215614 ! glucosamine metabolic process GO:0006041 10 10 0,000 0,0731081 0,12204549 GO:0006044|N-acetylglucosamine metabolic process, ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 10 10 0,000 0,0731081 0,12193504 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! inositol metabolic process GO:0006020 10 10 0,000 0,0731081 0,12182479 ! cAMP metabolic process GO:0046058 10 10 0,000 0,0731081 0,12171474 ! vesicle targeting, to, from or within Golgi GO:0048199 10 10 0,000 0,0731081 0,12160489 ! transcription from RNA polymerase III promoter GO:0006383 10 10 0,000 0,0731081 0,12149524 ! forelimb morphogenesis GO:0035136 10 10 0,000 0,0731081 0,12138578 ! glial cell development GO:0021782 10 10 0,000 0,0731081 0,12127653 ! phototransduction GO:0007602 11 10 0,000 0,0731081 0,12116746 ! calcium-independent cell-cell adhesion GO:0016338 10 10 0,000 0,0731081 0,1210586 ! auditory receptor cell differentiation GO:0042491 10 10 0,000 0,0731081 0,12094993 ! fat cell differentiation GO:0045444 10 10 0,000 0,0731081 0,12084145 ! myoblast differentiation GO:0045445 10 10 0,000 0,0731081 0,12073317 ! centrosome cycle GO:0007098 10 10 0,000 0,0731081 0,12062509 ! inactivation of MAPK activity GO:0000188 10 10 0,000 0,0731081 0,12051719 ! positive regulation of proteolysis GO:0045862 10 10 0,000 0,0731081 0,12040949 ! response to carbohydrate stimulus GO:0009743 10 10 0,000 0,0731081 0,12030198 ! regulation of survival gene product expression GO:0045884 10 10 0,000 0,0731081 0,12019467 ! induction of apoptosis via death domain receptors GO:0008625 10 10 0,000 0,0731081 0,12008754 ! epidermis morphogenesis GO:0048730 10 10 0,000 0,0731081 0,11998061 ! protein polyubiquitination GO:0000209 10 10 0,000 0,0731081 0,11987386 ! glutamate metabolic process GO:0006536 11 10 0,000 0,0731081 0,11976731 ! plasma membrane organization GO:0007009 10 10 0,000 0,0731081 0,11966094 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 10 10 0,000 0,0731081 0,11955477 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! lysosomal transport GO:0007041 10 10 0,000 0,0731081 0,11944878 ! cellular response to unfolded protein GO:0034620 10 10 0,000 0,0731081 0,11934298 GO:0030968|endoplasmic reticulum unfolded protein response, ! central nervous system neuron differentiation GO:0021953 11 10 0,000 0,0731081 0,11923736 ! purine ribonucleoside metabolic process GO:0046128 10 10 0,000 0,0731081 0,11913194 GO:0042278|purine nucleoside metabolic process, ! vesicle coating GO:0006901 10 10 0,000 0,0731081 0,1190267 ! exocrine system development GO:0035272 10 10 0,000 0,0731081 0,11892164 ! cell structure disassembly during apoptosis GO:0006921 10 10 0,000 0,0731081 0,11881677 ! embryo implantation GO:0007566 11 10 0,000 0,0731081 0,11871209 ! regulation of protein binding GO:0043393 11 10 0,000 0,0731081 0,11860759 ! protein targeting to peroxisome GO:0006625 10 10 0,000 0,0731081 0,11850327 ! protein targeting to mitochondrion GO:0006626 10 10 0,000 0,0731081 0,11839914 GO:0070585|protein localization in mitochondrion, ! regulation of alpha-beta T cell differentiation GO:0046637 10 10 0,000 0,0731081 0,11829519 ! intermediate filament cytoskeleton organization GO:0045104 10 10 0,000 0,0731081 0,11819142 ! protein export from nucleus GO:0006611 10 10 0,000 0,0731081 0,11808784 ! negative regulation of immune response GO:0050777 10 10 0,000 0,0731081 0,11798443 ! positive regulation of biomineral formation GO:0070169 10 10 0,000 0,0731081 0,11788121 GO:0030501|positive regulation of bone mineralization, ! mismatch repair GO:0006298 10 10 0,000 0,0731081 0,11777816 ! regulation of B cell differentiation GO:0045577 10 10 0,000 0,0731081 0,1176753 ! histone deacetylation GO:0016575 10 10 0,000 0,0731081 0,11757262 ! mRNA splice site selection GO:0006376 11 10 0,000 0,0731081 0,11747011 ! synaptic vesicle transport GO:0048489 11 10 0,000 0,0731081 0,11736779 ! gland morphogenesis GO:0022612 10 10 0,000 0,0731081 0,11726564 ! positive regulation of neurological system process GO:0031646 10 10 0,000 0,0731081 0,11716367 ! sphingolipid biosynthetic process GO:0030148 10 10 0,000 0,0731081 0,11706188 GO:0046467|membrane lipid biosynthetic process, ! sphingolipid catabolic process GO:0030149 10 10 0,000 0,0731081 0,11696026 GO:0046466|membrane lipid catabolic process, ! nerve-nerve synaptic transmission GO:0007270 10 10 0,000 0,0731081 0,11685882 ! regulation of epidermis development GO:0045682 10 10 0,000 0,0731081 0,11675756 ! folic acid and derivative metabolic process GO:0006760 10 10 0,000 0,0731081 0,11665647 ! negative regulation of neuron differentiation GO:0045665 10 10 0,000 0,0731081 0,11655555 ! aspartate family amino acid biosynthetic process GO:0009067 10 10 0,000 0,0731081 0,11645481 ! regulation of BMP signaling pathway GO:0030510 10 10 0,000 0,0731081 0,11635425 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 10 10 0,000 0,0731081 0,11625386 ! lymphocyte homeostasis GO:0002260 10 10 0,000 0,0731081 0,11615364 ! nerve development GO:0021675 10 10 0,000 0,0731081 0,11605359 ! gut development GO:0048565 10 10 0,000 0,0731081 0,11595372 ! embryonic organ morphogenesis GO:0048562 10 10 0,000 0,0731081 0,11585402 ! mRNA 3'-end processing GO:0031124 10 10 0,000 0,0731081 0,11575448 ! antigen receptor-mediated signaling pathway GO:0050851 10 10 0,000 0,0731081 0,11565512 ! negative regulation of coagulation GO:0050819 11 10 0,000 0,0731081 0,11555593 ! protein stabilization GO:0050821 10 10 0,000 0,0731081 0,11545692 ! potassium ion transport GO:0006813 60 60 1,000 0,07513902 0,11856268 ! proteasomal protein catabolic process GO:0010498 62 61 1,000 0,07732107 0,12190139 GO:0043161|proteasomal ubiquitin-dependent protein catabolic process, ! positive regulation of cellular protein metabolic process GO:0032270 61 61 1,000 0,07732107 0,1217972 ! morphogenesis of an epithelium GO:0002009 63 62 1,000 0,07952322 0,12515909 GO:0060429|epithelium development, ! protein import GO:0017038 62 62 1,000 0,07952322 0,1250523 ! regulation of lymphocyte activation GO:0051249 62 62 1,000 0,07952322 0,12494569 ! protein secretion GO:0009306 11 11 0,000 0,08012387 0,12578219 ! oligosaccharide metabolic process GO:0009311 11 11 0,000 0,08012387 0,12567514 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 11 11 0,000 0,08012387 0,12556828 ! myeloid leukocyte differentiation GO:0002573 12 11 0,000 0,08012387 0,12546159 ! negative regulation of defense response GO:0031348 11 11 0,000 0,08012387 0,12535509 ! determination of bilateral symmetry GO:0009855 11 11 0,000 0,08012387 0,12524877 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! positive regulation of hormone secretion GO:0046887 11 11 0,000 0,08012387 0,12514262 ! phosphatidylinositol metabolic process GO:0046488 11 11 0,000 0,08012387 0,12503666 ! skin development GO:0043588 11 11 0,000 0,08012387 0,12493088 ! cellular component assembly involved in morphogenesis GO:0010927 11 11 0,000 0,08012387 0,12482527 ! signal complex assembly GO:0007172 11 11 0,000 0,08012387 0,12471984 ! microtubule-based transport GO:0010970 11 11 0,000 0,08012387 0,12461459 ! endothelial cell migration GO:0043542 11 11 0,000 0,08012387 0,12450952 ! peroxisomal transport GO:0043574 11 11 0,000 0,08012387 0,12440463 ! protein amino acid methylation GO:0006479 11 11 0,000 0,08012387 0,12429991 GO:0008213|protein amino acid alkylation, ! heart contraction GO:0060047 11 11 0,000 0,08012387 0,12419537 GO:0003015|heart process, ! detection of light stimulus involved in sensory perception GO:0050962 12 11 0,000 0,08012387 0,124091 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 11 11 0,000 0,08012387 0,12398681 ! T cell proliferation GO:0042098 11 11 0,000 0,08012387 0,1238828 ! regulation of transmembrane transporter activity GO:0022898 11 11 0,000 0,08012387 0,12377896 GO:0032412|regulation of ion transmembrane transporter activity, GO:0032409|regulation of transporter activity, ! negative regulation of endothelial cell proliferation GO:0001937 11 11 0,000 0,08012387 0,12367529 ! regulation of viral genome replication GO:0045069 11 11 0,000 0,08012387 0,12357179 ! spinal cord development GO:0021510 11 11 0,000 0,08012387 0,12346847 ! smooth muscle contraction GO:0006939 11 11 0,000 0,08012387 0,12336533 ! cellular macromolecular complex disassembly GO:0034623 12 11 0,000 0,08012387 0,12326235 ! digestive system process GO:0022600 11 11 0,000 0,08012387 0,12315955 ! mitotic spindle organization GO:0007052 11 11 0,000 0,08012387 0,12305691 ! fucose metabolic process GO:0006004 11 11 0,000 0,08012387 0,12295445 ! membrane budding GO:0006900 11 11 0,000 0,08012387 0,12285216 ! apoptotic nuclear changes GO:0030262 11 11 0,000 0,08012387 0,12275004 ! monoamine transport GO:0015844 11 11 0,000 0,08012387 0,12264809 ! regulation of cellular ketone metabolic process GO:0010565 11 11 0,000 0,08012387 0,1225463 ! response to lipopolysaccharide GO:0032496 11 11 0,000 0,08012387 0,12244469 ! body fluid secretion GO:0007589 11 11 0,000 0,08012387 0,12234324 ! positive regulation of alpha-beta T cell activation GO:0046635 11 11 0,000 0,08012387 0,12224197 ! intermediate filament-based process GO:0045103 11 11 0,000 0,08012387 0,12214086 ! cardiac muscle tissue morphogenesis GO:0055008 11 11 0,000 0,08012387 0,12203991 GO:0060415|muscle tissue morphogenesis, ! membrane depolarization GO:0051899 11 11 0,000 0,08012387 0,12193914 ! regulation of interleukin-2 production GO:0032663 11 11 0,000 0,08012387 0,12183853 ! regulation of ARF GTPase activity GO:0032312 11 11 0,000 0,08012387 0,12173808 ! oogenesis GO:0048477 11 11 0,000 0,08012387 0,1216378 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 11 11 0,000 0,08012387 0,12153769 ! vitamin transport GO:0051180 11 11 0,000 0,08012387 0,12143774 ! vitamin A metabolic process GO:0006776 11 11 0,000 0,08012387 0,12133796 ! hindbrain development GO:0030902 11 11 0,000 0,08012387 0,12123834 ! steroid catabolic process GO:0006706 11 11 0,000 0,08012387 0,12113888 ! endocrine process GO:0050886 11 11 0,000 0,08012387 0,12103959 GO:0001990|regulation of systemic arterial blood pressure by hormone, ! aromatic amino acid family metabolic process GO:0009072 11 11 0,000 0,08012387 0,12094045 ! proximal/distal pattern formation GO:0009954 11 11 0,000 0,08012387 0,12084149 ! somatic diversification of immunoglobulins GO:0016445 11 11 0,000 0,08012387 0,12074268 ! RNA 3'-end processing GO:0031123 11 11 0,000 0,08012387 0,12064403 ! negative regulation of cellular component organization GO:0051129 65 63 1,000 0,08174505 0,1229846 ! regulation of response to external stimulus GO:0032101 65 64 1,000 0,08398617 0,12625327 ! angiogenesis GO:0001525 65 64 1,000 0,08398617 0,12615037 ! anion transport GO:0006820 65 65 1,000 0,08624615 0,12943946 ! positive regulation of cellular component organization GO:0051130 65 65 1,000 0,08624615 0,12933414 ! translational initiation GO:0006413 12 12 0,000 0,08708756 0,13048973 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 12 12 0,000 0,08708756 0,13038373 ! initiation of viral infection GO:0019059 12 12 0,000 0,08708756 0,1302779 ! DNA catabolic process, endonucleolytic GO:0000737 12 12 0,000 0,08708756 0,13017224 ! iron ion transport GO:0006826 13 12 0,000 0,08708756 0,13006675 ! phosphatidylcholine metabolic process GO:0046470 12 12 0,000 0,08708756 0,12996143 ! amino sugar metabolic process GO:0006040 12 12 0,000 0,08708756 0,12985628 ! post-Golgi vesicle-mediated transport GO:0006892 12 12 0,000 0,08708756 0,12975131 ! hindlimb morphogenesis GO:0035137 12 12 0,000 0,08708756 0,1296465 ! glutamate signaling pathway GO:0007215 12 12 0,000 0,08708756 0,12954186 ! C21-steroid hormone metabolic process GO:0008207 13 12 0,000 0,08708756 0,12943739 ! regulation of muscle cell differentiation GO:0051147 13 12 0,000 0,08708756 0,12933309 ! cellular response to hydrogen peroxide GO:0070301 12 12 0,000 0,08708756 0,12922896 GO:0042744|hydrogen peroxide catabolic process, ! negative regulation of peptidase activity GO:0010466 12 12 0,000 0,08708756 0,12912499 ! actomyosin structure organization GO:0031032 12 12 0,000 0,08708756 0,1290212 ! microtubule organizing center organization GO:0031023 12 12 0,000 0,08708756 0,12891756 GO:0051297|centrosome organization, ! positive regulation of endocytosis GO:0045807 12 12 0,000 0,08708756 0,1288141 ! retinoid metabolic process GO:0001523 12 12 0,000 0,08708756 0,1287108 GO:0016101|diterpenoid metabolic process, ! mitotic chromosome condensation GO:0007076 12 12 0,000 0,08708756 0,12860767 ! positive regulation of innate immune response GO:0045089 12 12 0,000 0,08708756 0,1285047 ! GPI anchor biosynthetic process GO:0006506 12 12 0,000 0,08708756 0,12840189 GO:0006505|GPI anchor metabolic process, ! glycoprotein catabolic process GO:0006516 13 12 0,000 0,08708756 0,12829925 ! acute-phase response GO:0006953 12 12 0,000 0,08708756 0,12819678 ! deoxyribonucleotide catabolic process GO:0009264 12 12 0,000 0,08708756 0,12809447 ! vacuolar transport GO:0007034 12 12 0,000 0,08708756 0,12799232 ! polysaccharide catabolic process GO:0000272 12 12 0,000 0,08708756 0,12789033 ! vesicle docking during exocytosis GO:0006904 12 12 0,000 0,08708756 0,12778851 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 12 12 0,000 0,08708756 0,12768685 ! barbed-end actin filament capping GO:0051016 12 12 0,000 0,08708756 0,12758535 GO:0051693|actin filament capping, ! osteoblast differentiation GO:0001649 12 12 0,000 0,08708756 0,12748401 ! male gonad development GO:0008584 12 12 0,000 0,08708756 0,12738283 ! regulation of insulin secretion GO:0050796 12 12 0,000 0,08708756 0,12728181 ! regulation of alpha-beta T cell activation GO:0046634 12 12 0,000 0,08708756 0,12718096 ! renal system process GO:0003014 12 12 0,000 0,08708756 0,12708026 ! regulation of tumor necrosis factor production GO:0032680 12 12 0,000 0,08708756 0,12697972 ! regulation of steroid metabolic process GO:0019218 12 12 0,000 0,08708756 0,12687934 ! fibroblast growth factor receptor signaling pathway GO:0008543 12 12 0,000 0,08708756 0,12677912 ! regulation of interleukin-6 production GO:0032675 12 12 0,000 0,08708756 0,12667906 ! pallium development GO:0021543 13 12 0,000 0,08708756 0,12657915 ! cell fate determination GO:0001709 12 12 0,000 0,08708756 0,12647941 ! positive regulation of multicellular organism growth GO:0040018 12 12 0,000 0,08708756 0,12637982 ! regulation of response to biotic stimulus GO:0002831 12 12 0,000 0,08708756 0,12628038 ! positive regulation of adaptive immune response GO:0002821 12 12 0,000 0,08708756 0,12618111 ! detection of light stimulus GO:0009583 13 12 0,000 0,08708756 0,12608199 ! synaptogenesis GO:0007416 12 12 0,000 0,08708756 0,12598302 ! fat-soluble vitamin metabolic process GO:0006775 12 12 0,000 0,08708756 0,12588421 ! hormone transport GO:0009914 12 12 0,000 0,08708756 0,12578555 ! neurotransmitter secretion GO:0007269 14 12 0,000 0,08708756 0,12568705 ! heme biosynthetic process GO:0006783 12 12 0,000 0,08708756 0,12558871 ! spermatid differentiation GO:0048515 13 12 0,000 0,08708756 0,12549051 GO:0007286|spermatid development, ! aromatic compound catabolic process GO:0019439 13 12 0,000 0,08708756 0,12539247 ! pyrimidine nucleotide biosynthetic process GO:0006221 12 12 0,000 0,08708756 0,12529459 ! neural tube closure GO:0001843 13 12 0,000 0,08708756 0,12519685 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! negative regulation of translation GO:0017148 12 12 0,000 0,08708756 0,12509927 ! regulation of microtubule polymerization or depolymerization GO:0031110 12 12 0,000 0,08708756 0,12500184 ! DNA packaging GO:0006323 66 66 1,000 0,08852461 0,12696565 ! polysaccharide metabolic process GO:0005976 69 66 1,000 0,08852461 0,12686692 ! Ras protein signal transduction GO:0007265 69 67 1,000 0,09082115 0,13005701 ! chromatin assembly or disassembly GO:0006333 68 68 1,000 0,09313537 0,13326745 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 13 13 0,000 0,09399953 0,13439964 GO:0016444|somatic cell DNA recombination, ! negative regulation of actin filament polymerization GO:0030837 13 13 0,000 0,09399953 0,13429546 ! phenol metabolic process GO:0018958 13 13 0,000 0,09399953 0,13419143 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, GO:0009712|catechol metabolic process, ! G2/M transition of mitotic cell cycle GO:0000086 13 13 0,000 0,09399953 0,13408757 ! gluconeogenesis GO:0006094 13 13 0,000 0,09399953 0,13398387 ! negative regulation of hormone secretion GO:0046888 13 13 0,000 0,09399953 0,13388032 ! 2'-deoxyribonucleotide metabolic process GO:0009394 13 13 0,000 0,09399953 0,13377694 GO:0019692|deoxyribose phosphate metabolic process, ! intra-Golgi vesicle-mediated transport GO:0006891 13 13 0,000 0,09399953 0,13367372 ! glycosaminoglycan biosynthetic process GO:0006024 13 13 0,000 0,09399953 0,13357065 ! positive regulation of JAK-STAT cascade GO:0046427 13 13 0,000 0,09399953 0,13346775 ! regeneration GO:0031099 13 13 0,000 0,09399953 0,133365 ! keratinization GO:0031424 13 13 0,000 0,09399953 0,13326241 ! post-embryonic development GO:0009791 14 13 0,000 0,09399953 0,13315998 ! negative regulation of protein modification process GO:0031400 13 13 0,000 0,09399953 0,13305771 ! patterning of blood vessels GO:0001569 13 13 0,000 0,09399953 0,13295559 ! regulation of DNA recombination GO:0000018 13 13 0,000 0,09399953 0,13285363 ! regulation of innate immune response GO:0045088 13 13 0,000 0,09399953 0,13275183 ! response to corticosteroid stimulus GO:0031960 13 13 0,000 0,09399953 0,13265018 GO:0051384|response to glucocorticoid stimulus, ! multicellular organismal catabolic process GO:0044243 13 13 0,000 0,09399953 0,13254869 ! autophagy GO:0006914 13 13 0,000 0,09399953 0,13244735 ! receptor metabolic process GO:0043112 14 13 0,000 0,09399953 0,13234617 ! negative regulation of protein catabolic process GO:0042177 13 13 0,000 0,09399953 0,13224514 ! ureteric bud development GO:0001657 13 13 0,000 0,09399953 0,13214427 ! coenzyme catabolic process GO:0009109 13 13 0,000 0,09399953 0,13204355 GO:0046356|acetyl-CoA catabolic process, GO:0006099|tricarboxylic acid cycle, ! negative regulation of protein kinase cascade GO:0010741 13 13 0,000 0,09399953 0,13194298 ! purine nucleoside monophosphate metabolic process GO:0009126 13 13 0,000 0,09399953 0,13184257 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of peptide secretion GO:0002791 13 13 0,000 0,09399953 0,13174231 ! regulation of viral reproduction GO:0050792 13 13 0,000 0,09399953 0,1316422 ! nucleobase metabolic process GO:0009112 13 13 0,000 0,09399953 0,13154225 ! regulation of axonogenesis GO:0050770 14 13 0,000 0,09399953 0,13144244 ! positive regulation of neurogenesis GO:0050769 13 13 0,000 0,09399953 0,13134279 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 14 13 0,000 0,09399953 0,13124329 ! nucleotide-excision repair, DNA gap filling GO:0006297 13 13 0,000 0,09399953 0,13114394 ! vasodilation GO:0042311 14 13 0,000 0,09399953 0,13104473 ! positive regulation of leukocyte mediated immunity GO:0002705 13 13 0,000 0,09399953 0,13094568 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 13 13 0,000 0,09399953 0,13084678 ! glycosphingolipid metabolic process GO:0006687 13 13 0,000 0,09399953 0,13074803 GO:0006664|glycolipid metabolic process, ! neutrophil chemotaxis GO:0030593 14 13 0,000 0,09399953 0,13064943 ! long-chain fatty acid transport GO:0015909 13 13 0,000 0,09399953 0,13055097 ! immunoglobulin production GO:0002377 13 13 0,000 0,09399953 0,13045266 GO:0002440|production of molecular mediator of immune response, ! negative regulation of myeloid cell differentiation GO:0045638 13 13 0,000 0,09399953 0,13035451 ! response to cytokine stimulus GO:0034097 13 13 0,000 0,09399953 0,1302565 ! terpenoid metabolic process GO:0006721 13 13 0,000 0,09399953 0,13015863 ! alkene biosynthetic process GO:0043450 13 13 0,000 0,09399953 0,13006091 GO:0019370|leukotriene biosynthetic process, ! purine nucleotide catabolic process GO:0006195 13 13 0,000 0,09399953 0,12996334 ! porphyrin biosynthetic process GO:0006779 13 13 0,000 0,09399953 0,12986592 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of cytokine production GO:0001818 13 13 0,000 0,09399953 0,12976864 ! camera-type eye morphogenesis GO:0048593 13 13 0,000 0,09399953 0,12967151 ! pyrimidine nucleoside metabolic process GO:0006213 13 13 0,000 0,09399953 0,12957452 ! blastocyst development GO:0001824 13 13 0,000 0,09399953 0,12947768 ! telomere organization GO:0032200 13 13 0,000 0,09399953 0,12938098 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 13 13 0,000 0,09399953 0,12928443 ! regulation of amine transport GO:0051952 13 13 0,000 0,09399953 0,12918802 ! inner ear receptor cell differentiation GO:0060113 13 13 0,000 0,09399953 0,12909176 ! regulation of leukocyte activation GO:0002694 69 69 1,000 0,09546689 0,13100929 ! positive regulation of transport GO:0051050 71 70 1,000 0,09781533 0,13413218 ! growth GO:0040007 70 70 1,000 0,09781533 0,13403246 ! negative regulation of signal transduction GO:0009968 71 71 1,000 0,10018032 0,13717112 ! regulation of cell activation GO:0050865 71 71 1,000 0,10018032 0,13706928 ! neuron fate commitment GO:0048663 14 14 0,000 0,10086017 0,13789711 ! sulfur amino acid metabolic process GO:0000096 14 14 0,000 0,10086017 0,13779489 ! regulation of interferon-gamma production GO:0032649 14 14 0,000 0,10086017 0,13769282 ! pyruvate metabolic process GO:0006090 14 14 0,000 0,10086017 0,1375909 ! cellular aldehyde metabolic process GO:0006081 14 14 0,000 0,10086017 0,13748913 ! acetyl-CoA metabolic process GO:0006084 14 14 0,000 0,10086017 0,13738751 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 14 14 0,000 0,10086017 0,13728604 ! regulation of neuron projection development GO:0010975 15 14 0,000 0,10086017 0,13718472 ! protein amino acid deacetylation GO:0006476 14 14 0,000 0,10086017 0,13708356 ! aminoglycan biosynthetic process GO:0006023 14 14 0,000 0,10086017 0,13698254 ! vesicle docking GO:0048278 14 14 0,000 0,10086017 0,13688166 ! superoxide metabolic process GO:0006801 15 14 0,000 0,10086017 0,13678094 ! macromolecular complex disassembly GO:0032984 15 14 0,000 0,10086017 0,13668037 ! mechanoreceptor differentiation GO:0042490 14 14 0,000 0,10086017 0,13657994 ! isoprenoid biosynthetic process GO:0008299 14 14 0,000 0,10086017 0,13647966 ! hair cycle GO:0042633 14 14 0,000 0,10086017 0,13637953 GO:0022404|molting cycle process, GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042303|molting cycle, ! immune response-activating cell surface receptor signaling pathway GO:0002429 14 14 0,000 0,10086017 0,13627955 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! multicellular organismal response to stress GO:0033555 14 14 0,000 0,10086017 0,13617971 ! lysosome organization GO:0007040 14 14 0,000 0,10086017 0,13608002 ! actin polymerization or depolymerization GO:0008154 15 14 0,000 0,10086017 0,13598047 ! D-ribose metabolic process GO:0006014 14 14 0,000 0,10086017 0,13588107 ! negative regulation of phosphorus metabolic process GO:0010563 14 14 0,000 0,10086017 0,13578181 GO:0045936|negative regulation of phosphate metabolic process, ! peptide transport GO:0015833 14 14 0,000 0,10086017 0,1356827 ! primary neural tube formation GO:0014020 15 14 0,000 0,10086017 0,13558373 ! vitamin biosynthetic process GO:0009110 14 14 0,000 0,10086017 0,13548491 ! response to organic cyclic substance GO:0014070 15 14 0,000 0,10086017 0,13538624 ! leukotriene metabolic process GO:0006691 14 14 0,000 0,10086017 0,1352877 ! regulation of vasoconstriction GO:0019229 14 14 0,000 0,10086017 0,13518931 ! formation of primary germ layer GO:0001704 14 14 0,000 0,10086017 0,13509106 GO:0001707|mesoderm formation, ! DNA modification GO:0006304 14 14 0,000 0,10086017 0,13499296 ! collagen fibril organization GO:0030199 14 14 0,000 0,10086017 0,13489499 ! proteoglycan biosynthetic process GO:0030166 14 14 0,000 0,10086017 0,13479717 ! regulation of blood coagulation GO:0030193 15 14 0,000 0,10086017 0,13469949 ! positive regulation of inflammatory response GO:0050729 14 14 0,000 0,10086017 0,13460196 ! group transfer coenzyme metabolic process GO:0006752 14 14 0,000 0,10086017 0,13450456 ! positive regulation of osteoblast differentiation GO:0045669 14 14 0,000 0,10086017 0,1344073 ! neuromuscular process controlling balance GO:0050885 14 14 0,000 0,10086017 0,13431019 ! aspartate family amino acid metabolic process GO:0009066 14 14 0,000 0,10086017 0,13421321 ! response to molecule of bacterial origin GO:0002237 14 14 0,000 0,10086017 0,13411638 ! negative regulation of protein polymerization GO:0032272 14 14 0,000 0,10086017 0,13401968 ! regulation of cytokine production GO:0001817 72 72 1,000 0,10256147 0,13618213 ! negative regulation of actin filament depolymerization GO:0030835 15 15 0,000 0,10766986 0,14286216 ! positive regulation of ossification GO:0045778 15 15 0,000 0,10766986 0,14275938 GO:0046852|positive regulation of bone remodeling, GO:0034105|positive regulation of tissue remodeling, ! negative regulation of protein complex assembly GO:0031333 15 15 0,000 0,10766986 0,14265675 ! protein amino acid O-linked glycosylation GO:0006493 15 15 0,000 0,10766986 0,14255427 ! cellular polysaccharide biosynthetic process GO:0033692 15 15 0,000 0,10766986 0,14245193 ! proteoglycan metabolic process GO:0006029 15 15 0,000 0,10766986 0,14234974 ! striated muscle cell differentiation GO:0051146 16 15 0,000 0,10766986 0,1422477 ! odontogenesis of dentine-containing tooth GO:0042475 15 15 0,000 0,10766986 0,1421458 ! detection of stimulus involved in sensory perception GO:0050906 16 15 0,000 0,10766986 0,14204405 ! ovarian follicle development GO:0001541 15 15 0,000 0,10766986 0,14194245 ! antigen processing and presentation of peptide antigen GO:0048002 15 15 0,000 0,10766986 0,14184099 ! regulation of smooth muscle contraction GO:0006940 15 15 0,000 0,10766986 0,14173967 ! deoxyribonucleotide metabolic process GO:0009262 15 15 0,000 0,10766986 0,1416385 ! heme metabolic process GO:0042168 15 15 0,000 0,10766986 0,14153748 ! mesoderm morphogenesis GO:0048332 15 15 0,000 0,10766986 0,1414366 ! chromosome condensation GO:0030261 15 15 0,000 0,10766986 0,14133586 ! response to mechanical stimulus GO:0009612 15 15 0,000 0,10766986 0,14123526 ! hydrogen peroxide metabolic process GO:0042743 15 15 0,000 0,10766986 0,14113481 ! regulation of biomineral formation GO:0070167 15 15 0,000 0,10766986 0,1410345 GO:0030500|regulation of bone mineralization, ! regulation of production of molecular mediator of immune response GO:0002700 15 15 0,000 0,10766986 0,14093433 ! cyclic nucleotide biosynthetic process GO:0009190 15 15 0,000 0,10766986 0,14083431 ! cholesterol biosynthetic process GO:0006695 15 15 0,000 0,10766986 0,14073443 ! phospholipid transport GO:0015914 15 15 0,000 0,10766986 0,14063469 ! leukocyte homeostasis GO:0001776 15 15 0,000 0,10766986 0,14053509 ! regulation of cytokine secretion GO:0050707 15 15 0,000 0,10766986 0,14043563 ! glutathione metabolic process GO:0006749 16 15 0,000 0,10766986 0,14033631 ! nicotinamide metabolic process GO:0006769 15 15 0,000 0,10766986 0,14023713 GO:0046496|nicotinamide nucleotide metabolic process, ! positive regulation of B cell activation GO:0050871 15 15 0,000 0,10766986 0,1401381 ! cellular alkene metabolic process GO:0043449 15 15 0,000 0,10766986 0,1400392 ! negative regulation of transcription factor activity GO:0043433 16 15 0,000 0,10766986 0,13994044 GO:0090048|negative regulation of transcription regulator activity, ! somatic diversification of immune receptors GO:0002200 15 15 0,000 0,10766986 0,13984182 ! positive regulation of immune effector process GO:0002699 15 15 0,000 0,10766986 0,13974334 ! negative regulation of cell communication GO:0010648 76 76 1,000 0,11224051 0,14557302 ! positive regulation of multicellular organismal process GO:0051240 76 76 1,000 0,11224051 0,14547065 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 16 16 0,000 0,11442895 0,14820278 ! negative regulation of adenylate cyclase activity GO:0007194 16 16 0,000 0,11442895 0,1480987 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! alkaloid metabolic process GO:0009820 16 16 0,000 0,11442895 0,14799477 ! regulation of synaptic plasticity GO:0048167 16 16 0,000 0,11442895 0,14789099 ! spliceosomal snRNP biogenesis GO:0000387 16 16 0,000 0,11442895 0,14778735 ! learning GO:0007612 16 16 0,000 0,11442895 0,14768386 ! inner ear morphogenesis GO:0042472 16 16 0,000 0,11442895 0,14758051 ! vacuole organization GO:0007033 16 16 0,000 0,11442895 0,14747731 ! cellular response to reactive oxygen species GO:0034614 16 16 0,000 0,11442895 0,14737425 ! positive regulation of cytoskeleton organization GO:0051495 16 16 0,000 0,11442895 0,14727133 ! vesicle targeting GO:0006903 17 16 0,000 0,11442895 0,14716856 ! fatty acid beta-oxidation GO:0006635 16 16 0,000 0,11442895 0,14706593 ! triglyceride metabolic process GO:0006641 16 16 0,000 0,11442895 0,14696345 ! positive regulation of cell development GO:0010720 16 16 0,000 0,11442895 0,14686111 ! regulation of myeloid leukocyte differentiation GO:0002761 17 16 0,000 0,11442895 0,14675891 ! lymphocyte proliferation GO:0046651 16 16 0,000 0,11442895 0,14665685 ! regulation of systemic arterial blood pressure GO:0003073 17 16 0,000 0,11442895 0,14655493 ! cell fate specification GO:0001708 16 16 0,000 0,11442895 0,14645316 ! pentose metabolic process GO:0019321 16 16 0,000 0,11442895 0,14635153 ! fatty acid transport GO:0015908 16 16 0,000 0,11442895 0,14625003 ! positive regulation of MAPKKK cascade GO:0043410 17 16 0,000 0,11442895 0,14614868 ! regulation of microtubule cytoskeleton organization GO:0070507 16 16 0,000 0,11442895 0,14604747 ! cofactor catabolic process GO:0051187 16 16 0,000 0,11442895 0,1459464 ! ethanolamine and derivative metabolic process GO:0042439 17 16 0,000 0,11442895 0,14584547 ! polyol metabolic process GO:0019751 16 16 0,000 0,11442895 0,14574468 ! serine family amino acid metabolic process GO:0009069 16 16 0,000 0,11442895 0,14564403 ! glutamine family amino acid catabolic process GO:0009065 17 16 0,000 0,11442895 0,14554351 ! porphyrin metabolic process GO:0006778 16 16 0,000 0,11442895 0,14544314 GO:0033013|tetrapyrrole metabolic process, ! embryonic epithelial tube formation GO:0001838 17 16 0,000 0,11442895 0,1453429 GO:0001841|neural tube formation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 17 16 0,000 0,11442895 0,1452428 ! regulation of coagulation GO:0050818 17 16 0,000 0,11442895 0,14514284 ! regulation of immune response GO:0050776 78 78 1,000 0,11716771 0,14851451 ! nuclear transport GO:0051169 79 79 1,000 0,11965201 0,15155922 GO:0006913|nucleocytoplasmic transport, ! positive regulation of NF-kappaB transcription factor activity GO:0051092 17 17 0,000 0,12113782 0,15333585 ! regulation of actin filament depolymerization GO:0030834 17 17 0,000 0,12113782 0,15323061 ! phosphoinositide biosynthetic process GO:0046489 17 17 0,000 0,12113782 0,15312551 ! regulation of transmembrane transport GO:0034762 17 17 0,000 0,12113782 0,15302056 ! nucleotide-excision repair, DNA damage removal GO:0000718 18 17 0,000 0,12113782 0,15291575 ! dicarboxylic acid metabolic process GO:0043648 18 17 0,000 0,12113782 0,15281109 ! sensory perception of smell GO:0007608 17 17 0,000 0,12113782 0,15270657 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 17 17 0,000 0,12113782 0,15260219 ! embryonic skeletal system morphogenesis GO:0048704 17 17 0,000 0,12113782 0,15249795 ! cellular carbohydrate biosynthetic process GO:0034637 17 17 0,000 0,12113782 0,15239386 ! development of primary male sexual characteristics GO:0046546 17 17 0,000 0,12113782 0,1522899 ! immune response-activating signal transduction GO:0002757 17 17 0,000 0,12113782 0,15218609 GO:0002764|immune response-regulating signal transduction, ! positive regulation of protein secretion GO:0050714 17 17 0,000 0,12113782 0,15208243 ! pyridine nucleotide metabolic process GO:0019362 17 17 0,000 0,12113782 0,1519789 ! pigmentation GO:0043473 17 17 0,000 0,12113782 0,15187551 ! myeloid leukocyte activation GO:0002274 18 17 0,000 0,12113782 0,15177226 ! adult locomotory behavior GO:0008344 17 17 0,000 0,12113782 0,15166916 ! regulation of calcium ion transport GO:0051924 17 17 0,000 0,12113782 0,15156619 ! gene silencing GO:0016458 17 17 0,000 0,12113782 0,15146337 ! mRNA export from nucleus GO:0006406 18 18 0,000 0,12779684 0,15968106 ! regulation of cell projection organization GO:0031344 19 18 0,000 0,12779684 0,15957288 ! icosanoid biosynthetic process GO:0046456 18 18 0,000 0,12779684 0,15946484 ! regulation of metal ion transport GO:0010959 18 18 0,000 0,12779684 0,15935695 ! membrane docking GO:0022406 18 18 0,000 0,12779684 0,1592492 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 18 18 0,000 0,12779684 0,1591416 ! mononuclear cell proliferation GO:0032943 18 18 0,000 0,12779684 0,15903414 GO:0070661|leukocyte proliferation, ! response to calcium ion GO:0051592 18 18 0,000 0,12779684 0,15892683 ! negative regulation of response to external stimulus GO:0032102 18 18 0,000 0,12779684 0,15881967 ! cholesterol homeostasis GO:0042632 18 18 0,000 0,12779684 0,15871265 GO:0055092|sterol homeostasis, ! striated muscle contraction GO:0006941 18 18 0,000 0,12779684 0,15860577 ! neutral lipid metabolic process GO:0006638 18 18 0,000 0,12779684 0,15849904 GO:0006639|acylglycerol metabolic process, ! ceramide metabolic process GO:0006672 18 18 0,000 0,12779684 0,15839245 GO:0046519|sphingoid metabolic process, ! ribonucleoside monophosphate metabolic process GO:0009161 18 18 0,000 0,12779684 0,158286 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! telencephalon development GO:0021537 19 18 0,000 0,12779684 0,1581797 ! hexose biosynthetic process GO:0019319 18 18 0,000 0,12779684 0,15807354 ! negative regulation of MAP kinase activity GO:0043407 18 18 0,000 0,12779684 0,15796752 ! BMP signaling pathway GO:0030509 18 18 0,000 0,12779684 0,15786164 ! regulation of microtubule-based process GO:0032886 18 18 0,000 0,12779684 0,15775591 ! negative regulation of catabolic process GO:0009895 18 18 0,000 0,12779684 0,15765031 ! establishment of vesicle localization GO:0051650 19 18 0,000 0,12779684 0,15754486 ! blood vessel morphogenesis GO:0048514 84 83 1,000 0,12971943 0,15980809 ! cellular amino acid derivative metabolic process GO:0006575 87 84 1,000 0,1322672 0,16283797 ! activation of adenylate cyclase activity GO:0007190 19 19 0,000 0,13440636 0,1653611 ! glial cell differentiation GO:0010001 19 19 0,000 0,13440636 0,16525078 ! regulation of JAK-STAT cascade GO:0046425 19 19 0,000 0,13440636 0,16514062 ! feeding behavior GO:0007631 19 19 0,000 0,13440636 0,1650306 ! peroxisome organization GO:0007031 19 19 0,000 0,13440636 0,16492072 ! positive regulation of T cell proliferation GO:0042102 19 19 0,000 0,13440636 0,16481099 ! regulation of striated muscle tissue development GO:0016202 20 19 0,000 0,13440636 0,16470141 ! metanephros development GO:0001656 19 19 0,000 0,13440636 0,16459198 ! ribonucleoside metabolic process GO:0009119 19 19 0,000 0,13440636 0,16448269 ! regulation of lymphocyte mediated immunity GO:0002706 19 19 0,000 0,13440636 0,16437354 ! positive regulation of T cell differentiation GO:0045582 19 19 0,000 0,13440636 0,16426454 ! nuclear-transcribed mRNA catabolic process GO:0000956 19 19 0,000 0,13440636 0,16415568 ! regulation of protein stability GO:0031647 19 19 0,000 0,13440636 0,16404697 ! eye morphogenesis GO:0048592 19 19 0,000 0,13440636 0,1639384 ! vesicle localization GO:0051648 20 19 0,000 0,13440636 0,16382998 ! positive regulation of cell differentiation GO:0045597 87 85 1,000 0,13482669 0,1642337 ! regulation of muscle development GO:0048634 21 20 0,000 0,14096676 0,17159956 ! negative regulation of cell adhesion GO:0007162 21 20 0,000 0,14096676 0,17148629 ! establishment or maintenance of cell polarity GO:0007163 21 20 0,000 0,14096676 0,17137317 ! organic ether metabolic process GO:0018904 20 20 0,000 0,14096676 0,17126021 GO:0006662|glycerol ether metabolic process, ! cytoskeleton-dependent intracellular transport GO:0030705 20 20 0,000 0,14096676 0,17114739 ! neural tube development GO:0021915 21 20 0,000 0,14096676 0,17103471 ! nucleus organization GO:0006997 20 20 0,000 0,14096676 0,17092219 ! phagocytosis GO:0006909 21 20 0,000 0,14096676 0,17080982 ! unsaturated fatty acid biosynthetic process GO:0006636 20 20 0,000 0,14096676 0,17069759 ! protein targeting to membrane GO:0006612 22 20 0,000 0,14096676 0,17058551 ! cyclic nucleotide metabolic process GO:0009187 20 20 0,000 0,14096676 0,17047358 ! chromatin remodeling GO:0006338 20 20 0,000 0,14096676 0,17036179 ! detection of abiotic stimulus GO:0009582 21 20 0,000 0,14096676 0,17025015 ! lipid oxidation GO:0034440 20 20 0,000 0,14096676 0,17013866 GO:0019395|fatty acid oxidation, ! female gamete generation GO:0007292 20 20 0,000 0,14096676 0,17002731 ! negative regulation of neuron apoptosis GO:0043524 21 20 0,000 0,14096676 0,16991611 ! monosaccharide biosynthetic process GO:0046364 20 20 0,000 0,14096676 0,16980505 ! RNA modification GO:0009451 20 20 0,000 0,14096676 0,16969414 ! single fertilization GO:0007338 21 20 0,000 0,14096676 0,16958338 ! regulation of B cell activation GO:0050864 20 20 0,000 0,14096676 0,16947275 ! cellular di-, tri-valent inorganic cation homeostasis GO:0030005 89 89 1,000 0,14517572 0,17441907 ! mRNA catabolic process GO:0006402 21 21 0,000 0,14747838 0,17707013 ! positive regulation of adenylate cyclase activity GO:0045762 21 21 0,000 0,14747838 0,17695485 GO:0051349|positive regulation of lyase activity, GO:0031281|positive regulation of cyclase activity, ! protein amino acid lipidation GO:0006497 21 21 0,000 0,14747838 0,17683972 ! receptor-mediated endocytosis GO:0006898 21 21 0,000 0,14747838 0,17672474 ! Notch signaling pathway GO:0007219 22 21 0,000 0,14747838 0,17660991 ! morphogenesis of embryonic epithelium GO:0016331 22 21 0,000 0,14747838 0,17649523 ! ear morphogenesis GO:0042471 21 21 0,000 0,14747838 0,1763807 ! cholesterol transport GO:0030301 21 21 0,000 0,14747838 0,17626631 GO:0015918|sterol transport, ! spliceosome assembly GO:0000245 22 21 0,000 0,14747838 0,17615208 ! regulation of Rab protein signal transduction GO:0032483 21 21 0,000 0,14747838 0,17603799 GO:0032313|regulation of Rab GTPase activity, ! regulation of leukocyte mediated immunity GO:0002703 21 21 0,000 0,14747838 0,17592405 ! regulation of multicellular organism growth GO:0040014 21 21 0,000 0,14747838 0,17581025 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 21 21 0,000 0,14747838 0,17569661 ! regulation of proteolysis GO:0030162 21 21 0,000 0,14747838 0,17558311 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 21 21 0,000 0,14747838 0,17546976 ! brain development GO:0007420 91 90 1,000 0,14778922 0,17572615 ! di-, tri-valent inorganic cation homeostasis GO:0055066 91 91 1,000 0,15041262 0,17873015 ! DNA replication GO:0006260 91 91 1,000 0,15041262 0,17861499 ! energy derivation by oxidation of organic compounds GO:0015980 94 92 1,000 0,15304564 0,18162467 ! RNA export from nucleus GO:0006405 22 22 0,000 0,15394158 0,18257036 ! cellular amide metabolic process GO:0043603 22 22 0,000 0,15394158 0,18245295 ! regulation of ion transport GO:0043269 22 22 0,000 0,15394158 0,18233569 ! odontogenesis GO:0042476 22 22 0,000 0,15394158 0,18221859 ! positive regulation of lymphocyte proliferation GO:0050671 22 22 0,000 0,15394158 0,18210163 GO:0032946|positive regulation of mononuclear cell proliferation, GO:0070665|positive regulation of leukocyte proliferation, GO:0070668|positive regulation of mast cell proliferation, ! hormone-mediated signaling GO:0009755 22 22 0,000 0,15394158 0,18198482 ! embryonic skeletal system development GO:0048706 22 22 0,000 0,15394158 0,18186817 ! ovulation cycle process GO:0022602 22 22 0,000 0,15394158 0,18175166 ! pigment biosynthetic process GO:0046148 22 22 0,000 0,15394158 0,1816353 ! cell chemotaxis GO:0060326 23 22 0,000 0,15394158 0,18151909 GO:0030595|leukocyte chemotaxis, ! respiratory gaseous exchange GO:0007585 22 22 0,000 0,15394158 0,18140303 ! erythrocyte differentiation GO:0030218 23 22 0,000 0,15394158 0,18128712 ! male sex differentiation GO:0046661 22 22 0,000 0,15394158 0,18117135 ! sterol biosynthetic process GO:0016126 22 22 0,000 0,15394158 0,18105574 ! biopolymer methylation GO:0043414 22 22 0,000 0,15394158 0,18094027 GO:0032259|methylation, ! regulation of adaptive immune response GO:0002819 22 22 0,000 0,15394158 0,18082495 ! detection of external stimulus GO:0009581 23 22 0,000 0,15394158 0,18070977 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 22 22 0,000 0,15394158 0,18059474 ! positive regulation of lymphocyte differentiation GO:0045621 22 22 0,000 0,15394158 0,18047986 ! fatty acid catabolic process GO:0009062 23 22 0,000 0,15394158 0,18036512 ! aerobic respiration GO:0009060 22 22 0,000 0,15394158 0,18025053 ! cytokine production GO:0001816 22 22 0,000 0,15394158 0,18013609 ! pyrimidine nucleotide metabolic process GO:0006220 22 22 0,000 0,15394158 0,18002179 ! tissue morphogenesis GO:0048729 94 93 1,000 0,15568798 0,18194861 ! regulation of response to stress GO:0080134 97 94 1,000 0,15833937 0,18492995 ! blood vessel development GO:0001568 95 94 1,000 0,15833937 0,18481283 ! epidermis development GO:0008544 94 94 1,000 0,15833937 0,18469586 ! response to hydrogen peroxide GO:0042542 24 23 0,000 0,16035672 0,1869307 ! viral infectious cycle GO:0019058 23 23 0,000 0,16035672 0,18681254 ! regulation of hormone secretion GO:0046883 23 23 0,000 0,16035672 0,18669453 ! response to estrogen stimulus GO:0043627 23 23 0,000 0,16035672 0,18657667 ! negative regulation of protein complex disassembly GO:0043242 23 23 0,000 0,16035672 0,18645896 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 23 23 0,000 0,16035672 0,18634139 ! induction of apoptosis by extracellular signals GO:0008624 23 23 0,000 0,16035672 0,18622397 ! regulation of ARF protein signal transduction GO:0032012 23 23 0,000 0,16035672 0,1861067 ! lipoprotein biosynthetic process GO:0042158 23 23 0,000 0,16035672 0,18598958 ! female gonad development GO:0008585 23 23 0,000 0,16035672 0,18587261 ! lipid homeostasis GO:0055088 23 23 0,000 0,16035672 0,18575578 ! cell projection assembly GO:0030031 25 23 0,000 0,16035672 0,1856391 ! regulation of cell growth GO:0001558 97 96 1,000 0,16366816 0,18935368 ! vasculature development GO:0001944 97 96 1,000 0,16366816 0,18923489 ! cellular amino acid biosynthetic process GO:0008652 24 24 0,000 0,16672415 0,19264741 ! heterocycle biosynthetic process GO:0018130 24 24 0,000 0,16672415 0,1925267 ! nucleotide catabolic process GO:0009166 24 24 0,000 0,16672415 0,19240614 ! erythrocyte homeostasis GO:0034101 25 24 0,000 0,16672415 0,19228574 ! ovulation cycle GO:0042698 24 24 0,000 0,16672415 0,19216549 ! fertilization GO:0009566 25 24 0,000 0,16672415 0,19204538 ! oxidoreduction coenzyme metabolic process GO:0006733 24 24 0,000 0,16672415 0,19192543 ! epithelial tube morphogenesis GO:0060562 25 24 0,000 0,16672415 0,19180563 ! glycoprotein metabolic process GO:0009100 99 98 1,000 0,16902981 0,19433684 ! blood circulation GO:0008015 99 98 1,000 0,16902981 0,19421568 GO:0003013|circulatory system process, ! ectoderm development GO:0007398 99 99 1,000 0,1717223 0,19718641 ! regulation of actin filament polymerization GO:0030833 25 25 0,000 0,17304421 0,19858063 ! negative regulation of secretion GO:0051048 26 25 0,000 0,17304421 0,19845705 ! protein amino acid N-linked glycosylation GO:0006487 25 25 0,000 0,17304421 0,19833364 ! sensory perception of chemical stimulus GO:0007606 25 25 0,000 0,17304421 0,19821037 ! cellular component disassembly GO:0022411 26 25 0,000 0,17304421 0,19808726 ! endosome transport GO:0016197 25 25 0,000 0,17304421 0,1979643 ! alcohol biosynthetic process GO:0046165 25 25 0,000 0,17304421 0,19784149 ! development of primary female sexual characteristics GO:0046545 25 25 0,000 0,17304421 0,19771884 GO:0046660|female sex differentiation, ! polysaccharide biosynthetic process GO:0000271 25 25 0,000 0,17304421 0,19759634 ! excretion GO:0007588 25 25 0,000 0,17304421 0,19747399 ! generation of a signal involved in cell-cell signaling GO:0003001 27 25 0,000 0,17304421 0,19735179 ! gastrulation GO:0007369 25 25 0,000 0,17304421 0,19722974 ! icosanoid metabolic process GO:0006690 25 25 0,000 0,17304421 0,19710784 ! regulation of endocytosis GO:0030100 25 25 0,000 0,17304421 0,19698609 ! JAK-STAT cascade GO:0007259 26 25 0,000 0,17304421 0,1968645 ! positive regulation of defense response GO:0031349 26 26 0,000 0,17931726 0,2038752 ! glycolysis GO:0006096 26 26 0,000 0,17931726 0,20374951 ! transforming growth factor beta receptor signaling pathway GO:0007179 26 26 0,000 0,17931726 0,20362397 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 26 26 0,000 0,17931726 0,20349859 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 26 26 0,000 0,17931726 0,20337336 ! cellular defense response GO:0006968 26 26 0,000 0,17931726 0,20324828 ! positive regulation of cytokine biosynthetic process GO:0042108 26 26 0,000 0,17931726 0,20312336 ! regulation of protein secretion GO:0050708 26 26 0,000 0,17931726 0,20299859 ! germ cell development GO:0007281 27 26 0,000 0,17931726 0,20287397 ! regulation of blood vessel size GO:0050880 27 26 0,000 0,17931726 0,20274951 GO:0035150|regulation of tube size, ! pigment metabolic process GO:0042440 26 26 0,000 0,17931726 0,2026252 ! chloride transport GO:0006821 27 27 0,000 0,18554362 0,20953241 ! monocarboxylic acid transport GO:0015718 27 27 0,000 0,18554362 0,2094041 ! cAMP-mediated signaling GO:0019933 27 27 0,000 0,18554362 0,20927594 ! peptide metabolic process GO:0006518 29 27 0,000 0,18554362 0,20914795 ! inner ear development GO:0048839 27 27 0,000 0,18554362 0,20902011 ! defense response to bacterium GO:0042742 27 27 0,000 0,18554362 0,20889242 ! isoprenoid metabolic process GO:0006720 27 27 0,000 0,18554362 0,20876489 ! glutamine family amino acid metabolic process GO:0009064 28 27 0,000 0,18554362 0,20863752 ! tRNA aminoacylation for protein translation GO:0006418 28 28 0,000 0,19172365 0,2154553 GO:0043038|amino acid activation, GO:0043039|tRNA aminoacylation, ! neuromuscular process GO:0050905 28 28 0,000 0,19172365 0,215324 ! regulation of muscle contraction GO:0006937 28 28 0,000 0,19172365 0,21519286 ! unsaturated fatty acid metabolic process GO:0033559 28 28 0,000 0,19172365 0,21506189 ! sulfur compound biosynthetic process GO:0044272 28 28 0,000 0,19172365 0,21493107 ! developmental growth GO:0048589 28 28 0,000 0,19172365 0,21480042 ! glycerophospholipid biosynthetic process GO:0046474 30 29 0,000 0,19785768 0,22153809 ! phosphoinositide metabolic process GO:0030384 29 29 0,000 0,19785768 0,22140358 ! leukocyte migration GO:0050900 30 29 0,000 0,19785768 0,22126924 ! antigen processing and presentation GO:0019882 29 29 0,000 0,19785768 0,22113505 ! DNA-dependent DNA replication GO:0006261 29 29 0,000 0,19785768 0,22100103 ! tRNA processing GO:0008033 29 29 0,000 0,19785768 0,22086717 ! regulation of gene expression, epigenetic GO:0040029 29 29 0,000 0,19785768 0,22073347 ! adult behavior GO:0030534 30 29 0,000 0,19785768 0,22059994 ! regulation of protein polymerization GO:0032271 29 29 0,000 0,19785768 0,22046657 ! transition metal ion transport GO:0000041 31 30 0,000 0,20394604 0,22711333 ! RNA catabolic process GO:0006401 30 30 0,000 0,20394604 0,22697618 ! response to reactive oxygen species GO:0000302 31 30 0,000 0,20394604 0,2268392 ! ER to Golgi vesicle-mediated transport GO:0006888 30 30 0,000 0,20394604 0,22670239 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 30 30 0,000 0,20394604 0,22656574 ! neuropeptide signaling pathway GO:0007218 30 30 0,000 0,20394604 0,22642925 ! regulation of protein complex disassembly GO:0043244 30 30 0,000 0,20394604 0,22629293 ! positive regulation of protein amino acid phosphorylation GO:0001934 30 30 0,000 0,20394604 0,22615678 ! skeletal system morphogenesis GO:0048705 31 30 0,000 0,20394604 0,22602078 ! regulation of inflammatory response GO:0050727 30 30 0,000 0,20394604 0,22588495 ! water-soluble vitamin metabolic process GO:0006767 30 30 0,000 0,20394604 0,22574929 ! vesicle organization GO:0016050 30 30 0,000 0,20394604 0,22561378 ! negative regulation of cytoskeleton organization GO:0051494 32 31 0,000 0,20998908 0,2321595 ! lipoprotein metabolic process GO:0042157 31 31 0,000 0,20998908 0,23202031 ! ion transmembrane transport GO:0034220 31 31 0,000 0,20998908 0,23188129 GO:0015985|energy coupled proton transport, down electrochemical gradient, GO:0015986|ATP synthesis coupled proton transport, ! glycerolipid biosynthetic process GO:0045017 32 31 0,000 0,20998908 0,23174244 ! digestion GO:0007586 31 31 0,000 0,20998908 0,23160376 ! nucleoside metabolic process GO:0009116 31 31 0,000 0,20998908 0,23146524 ! regulation of heart contraction GO:0008016 31 31 0,000 0,20998908 0,23132688 ! sphingolipid metabolic process GO:0006665 31 31 0,000 0,20998908 0,2311887 ! camera-type eye development GO:0043010 31 31 0,000 0,20998908 0,23105067 ! extracellular matrix organization GO:0030198 31 31 0,000 0,20998908 0,23091282 ! ribonucleoprotein complex assembly GO:0022618 32 31 0,000 0,20998908 0,23077512 ! cell redox homeostasis GO:0045454 32 32 0,000 0,21598712 0,23722543 ! glucose catabolic process GO:0006007 32 32 0,000 0,21598712 0,23708414 ! lipid modification GO:0030258 32 32 0,000 0,21598712 0,23694301 ! glycosaminoglycan metabolic process GO:0030203 34 32 0,000 0,21598712 0,23680206 ! regulation of vesicle-mediated transport GO:0060627 33 32 0,000 0,21598712 0,23666127 ! nuclear export GO:0051168 32 32 0,000 0,21598712 0,23652066 ! kidney development GO:0001822 32 32 0,000 0,21598712 0,2363802 ! regulation of protein complex assembly GO:0043254 33 33 0,000 0,22194049 0,24275153 ! membrane lipid metabolic process GO:0006643 33 33 0,000 0,22194049 0,24260755 ! regulation of actin polymerization or depolymerization GO:0008064 33 33 0,000 0,22194049 0,24246374 ! regulation of neuron differentiation GO:0045664 34 33 0,000 0,22194049 0,2423201 ! regulation of synaptic transmission GO:0050804 33 33 0,000 0,22194049 0,24217663 ! regulation of actin filament length GO:0030832 34 34 0,000 0,22784951 0,24847731 ! response to metal ion GO:0010038 34 34 0,000 0,22784951 0,24833037 ! ear development GO:0043583 34 34 0,000 0,22784951 0,2481836 ! muscle cell differentiation GO:0042692 35 34 0,000 0,22784951 0,24803701 ! coenzyme biosynthetic process GO:0009108 34 34 0,000 0,22784951 0,24789059 ! nucleoside monophosphate biosynthetic process GO:0009124 34 34 0,000 0,22784951 0,24774434 ! regulation of lipid metabolic process GO:0019216 34 34 0,000 0,22784951 0,24759826 ! secondary metabolic process GO:0019748 34 34 0,000 0,22784951 0,24745236 ! negative regulation of response to stimulus GO:0048585 34 34 0,000 0,22784951 0,24730663 ! detection of stimulus GO:0051606 36 34 0,000 0,22784951 0,24716107 ! regulation of cellular component size GO:0032535 35 35 0,000 0,23371452 0,25337404 ! regulation of cytokine biosynthetic process GO:0042035 35 35 0,000 0,23371452 0,25322508 ! multicellular organism reproduction GO:0032504 36 35 0,000 0,23371452 0,2530763 GO:0048609|reproductive process in a multicellular organism, ! inorganic anion transport GO:0015698 35 35 0,000 0,23371452 0,25292769 ! response to steroid hormone stimulus GO:0048545 35 35 0,000 0,23371452 0,25277926 ! regulation of immune effector process GO:0002697 35 35 0,000 0,23371452 0,252631 ! hydrogen transport GO:0006818 36 36 0,000 0,23953583 0,2587717 GO:0015992|proton transport, ! response to inorganic substance GO:0010035 36 36 0,000 0,23953583 0,25862011 ! aminoglycan metabolic process GO:0006022 38 36 0,000 0,23953583 0,25846869 ! oxygen and reactive oxygen species metabolic process GO:0006800 37 36 0,000 0,23953583 0,25831745 ! embryonic limb morphogenesis GO:0030326 36 36 0,000 0,23953583 0,25816639 GO:0035113|embryonic appendage morphogenesis, ! female pregnancy GO:0007565 37 36 0,000 0,23953583 0,2580155 ! RNA elongation from RNA polymerase II promoter GO:0006368 36 36 0,000 0,23953583 0,25786479 ! heterocycle catabolic process GO:0046700 36 36 0,000 0,23953583 0,25771426 ! regulation of transmission of nerve impulse GO:0051969 36 36 0,000 0,23953583 0,2575639 ! gonad development GO:0008406 36 36 0,000 0,23953583 0,25741372 ! regulation of adenylate cyclase activity GO:0045761 37 37 0,000 0,24531375 0,26346926 GO:0031279|regulation of cyclase activity, GO:0051339|regulation of lyase activity, ! eye development GO:0001654 37 37 0,000 0,24531375 0,26331581 ! ATP synthesis coupled electron transport GO:0042773 37 37 0,000 0,24531375 0,26316254 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! cellular amino acid catabolic process GO:0009063 38 37 0,000 0,24531375 0,26300945 ! regulation of Rho protein signal transduction GO:0035023 37 37 0,000 0,24531375 0,26285654 ! positive regulation of secretion GO:0051047 39 38 0,000 0,25104862 0,26884521 ! exocytosis GO:0006887 40 38 0,000 0,25104862 0,26868909 ! hexose catabolic process GO:0019320 38 38 0,000 0,25104862 0,26853314 ! RNA elongation GO:0006354 38 38 0,000 0,25104862 0,26837738 ! regulation of neurological system process GO:0031644 38 38 0,000 0,25104862 0,2682218 ! regulation of cAMP biosynthetic process GO:0030817 39 39 0,000 0,25674074 0,27414437 ! positive regulation of protein modification process GO:0031401 39 39 0,000 0,25674074 0,27398563 ! nucleoside monophosphate metabolic process GO:0009123 39 39 0,000 0,25674074 0,27382707 ! fatty acid biosynthetic process GO:0006633 39 39 0,000 0,25674074 0,2736687 ! cytokine-mediated signaling pathway GO:0019221 39 39 0,000 0,25674074 0,27351051 ! intracellular protein transmembrane transport GO:0065002 39 39 0,000 0,25674074 0,2733525 ! positive regulation of T cell activation GO:0050870 39 39 0,000 0,25674074 0,27319468 ! limb development GO:0060173 39 39 0,000 0,25674074 0,27303703 GO:0048736|appendage development, GO:0035107|appendage morphogenesis, ! regulation of cAMP metabolic process GO:0030814 40 40 0,000 0,26239042 0,2788844 ! DNA catabolic process GO:0006308 41 40 0,000 0,26239042 0,27872366 ! myeloid cell differentiation GO:0030099 42 40 0,000 0,26239042 0,2785631 ! regulation of nucleotide biosynthetic process GO:0030808 41 41 0,000 0,26799798 0,28435249 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! amine catabolic process GO:0009310 42 41 0,000 0,26799798 0,28418888 ! elevation of cytosolic calcium ion concentration GO:0007204 41 41 0,000 0,26799798 0,28402546 ! phospholipid biosynthetic process GO:0008654 42 41 0,000 0,26799798 0,28386223 ! regulation of Ras GTPase activity GO:0032318 41 41 0,000 0,26799798 0,28369918 ! monosaccharide catabolic process GO:0046365 41 41 0,000 0,26799798 0,28353632 ! respiratory electron transport chain GO:0022904 43 42 0,000 0,27356372 0,28925871 ! regulation of cyclic nucleotide metabolic process GO:0030799 42 42 0,000 0,27356372 0,28909285 ! cytosolic calcium ion homeostasis GO:0051480 42 42 0,000 0,27356372 0,28892718 ! development of primary sexual characteristics GO:0045137 42 42 0,000 0,27356372 0,2887617 ! negative regulation of ligase activity GO:0051352 43 42 0,000 0,27356372 0,28859641 GO:0051444|negative regulation of ubiquitin-protein ligase activity, GO:0051436|negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 43 43 0,000 0,27908795 0,29425577 ! alcohol catabolic process GO:0046164 43 43 0,000 0,27908795 0,29408753 ! homeostasis of number of cells GO:0048872 44 43 0,000 0,27908795 0,29391948 ! regulation of nucleotide metabolic process GO:0006140 43 43 0,000 0,27908795 0,29375162 ! mRNA transport GO:0051028 44 44 0,000 0,28457097 0,29935177 ! vitamin metabolic process GO:0006766 44 44 0,000 0,28457097 0,29918101 ! positive regulation of lymphocyte activation GO:0051251 44 44 0,000 0,28457097 0,29901044 ! regulation of actin cytoskeleton organization GO:0032956 46 45 0,000 0,29001309 0,30455506 ! steroid biosynthetic process GO:0006694 46 45 0,000 0,29001309 0,30438162 ! regulation of actin filament-based process GO:0032970 47 46 0,000 0,2954146 0,30987428 ! cyclic-nucleotide-mediated signaling GO:0019935 46 46 0,000 0,2954146 0,30969801 ! transcription initiation from RNA polymerase II promoter GO:0006367 46 46 0,000 0,2954146 0,30952195 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 47 47 0,000 0,3007758 0,31496011 ! regulation of blood pressure GO:0008217 48 47 0,000 0,3007758 0,31478126 ! calcium ion transport GO:0006816 48 48 0,000 0,30609699 0,32016841 ! glycerophospholipid metabolic process GO:0006650 49 48 0,000 0,30609699 0,31998681 ! DNA recombination GO:0006310 48 48 0,000 0,30609699 0,31980541 ! cellular lipid catabolic process GO:0044242 50 49 0,000 0,31137845 0,32513908 ! divalent metal ion transport GO:0070838 49 49 0,000 0,31137845 0,32495497 ! response to bacterium GO:0009617 50 49 0,000 0,31137845 0,32477107 ! cofactor biosynthetic process GO:0051188 49 49 0,000 0,31137845 0,32458738 ! positive regulation of cell activation GO:0050867 49 49 0,000 0,31137845 0,32440389 GO:0002696|positive regulation of leukocyte activation, ! regulation of defense response GO:0031347 50 50 0,000 0,31662048 0,32967884 ! RNA transport GO:0050658 50 50 0,000 0,31662048 0,32949269 GO:0050657|nucleic acid transport, GO:0051236|establishment of RNA localization, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 50 50 0,000 0,31662048 0,32930674 ! nitrogen compound catabolic process GO:0044270 51 50 0,000 0,31662048 0,32912101 ! transcription initiation GO:0006352 50 50 0,000 0,31662048 0,32893548 ! rRNA metabolic process GO:0016072 51 51 0,000 0,32182337 0,33415238 GO:0006364|rRNA processing, ! ATP biosynthetic process GO:0006754 51 51 0,000 0,32182337 0,33396423 ! RNA localization GO:0006403 52 52 0,000 0,3269874 0,33913212 ! cholesterol metabolic process GO:0008203 52 52 0,000 0,3269874 0,33894139 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 52 52 0,000 0,3269874 0,33875086 ! regulation of GTPase activity GO:0043087 53 52 0,000 0,3269874 0,33856055 ! sodium ion transport GO:0006814 53 53 0,000 0,33211287 0,34367435 ! tRNA metabolic process GO:0006399 53 53 0,000 0,33211287 0,34348149 ! carbohydrate biosynthetic process GO:0016051 53 53 0,000 0,33211287 0,34328885 ! carbohydrate catabolic process GO:0016052 53 53 0,000 0,33211287 0,34309642 ! response to virus GO:0009615 54 54 0,000 0,33720004 0,34815668 ! sulfur metabolic process GO:0006790 55 54 0,000 0,33720004 0,34796174 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 55 55 0,000 0,3422492 0,35297442 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! ribonucleoside triphosphate biosynthetic process GO:0009201 56 56 0,000 0,34726064 0,35794259 ! ATP metabolic process GO:0046034 57 57 0,000 0,35223462 0,36286663 ! nucleoside triphosphate biosynthetic process GO:0009142 57 57 0,000 0,35223462 0,36266391 ! sterol metabolic process GO:0016125 59 59 0,000 0,36207132 0,37258372 ! negative regulation of cellular protein metabolic process GO:0032269 60 60 0,000 0,36693458 0,37737747 ! protein polymerization GO:0051258 65 60 0,000 0,36693458 0,377167 ! cellular respiration GO:0045333 62 61 0,000 0,37176147 0,38191549 ! carboxylic acid catabolic process GO:0046395 63 61 0,000 0,37176147 0,38170272 GO:0016054|organic acid catabolic process, ! lipid transport GO:0006869 62 62 0,000 0,37655226 0,38640635 ! purine ribonucleoside triphosphate metabolic process GO:0009205 62 62 0,000 0,37655226 0,38619133 ! regulation of cellular component biogenesis GO:0044087 63 62 0,000 0,37655226 0,38597654 ! di-, tri-valent inorganic cation transport GO:0015674 63 62 0,000 0,37655226 0,38576199 ! regulation of secretion GO:0051046 65 63 0,000 0,38130721 0,39041622 ! glucose metabolic process GO:0006006 63 63 0,000 0,38130721 0,39019944 ! ribonucleoside triphosphate metabolic process GO:0009199 63 63 0,000 0,38130721 0,3899829 ! purine nucleoside triphosphate metabolic process GO:0009144 63 63 0,000 0,38130721 0,38976661 ! glycerolipid metabolic process GO:0046486 65 64 0,000 0,38602659 0,39437196 ! regulation of cytoskeleton organization GO:0051493 66 64 0,000 0,38602659 0,39415347 ! protein amino acid glycosylation GO:0006486 66 66 0,000 0,39535968 0,40345952 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! nucleoside triphosphate metabolic process GO:0009141 66 66 0,000 0,39535968 0,40323624 ! negative regulation of protein metabolic process GO:0051248 66 66 0,000 0,39535968 0,40301321 ! Golgi vesicle transport GO:0048193 67 67 0,000 0,3999739 0,40749138 ! muscle contraction GO:0006936 67 67 0,000 0,3999739 0,40726624 ! purine ribonucleotide biosynthetic process GO:0009152 68 68 0,000 0,40455358 0,41170196 ! sensory perception of sound GO:0007605 71 69 0,000 0,40909897 0,41609791 GO:0050954|sensory perception of mechanical stimulus, ! carboxylic acid biosynthetic process GO:0046394 70 70 0,000 0,41361033 0,42045441 GO:0016053|organic acid biosynthetic process, ! translational elongation GO:0006414 71 71 0,000 0,4180879 0,42477178 ! oxidative phosphorylation GO:0006119 71 71 0,000 0,4180879 0,42453774 ! calcium ion homeostasis GO:0055074 71 71 0,000 0,4180879 0,42430397 GO:0006874|cellular calcium ion homeostasis, ! ribosome biogenesis GO:0042254 71 71 0,000 0,4180879 0,42407045 ! secretion by cell GO:0032940 75 72 0,000 0,42253194 0,42834233 ! muscle system process GO:0003012 72 72 0,000 0,42253194 0,42810685 ! sensory organ development GO:0007423 72 72 0,000 0,42253194 0,42787163 ! electron transport chain GO:0022900 75 74 0,000 0,43132038 0,43653128 ! coenzyme metabolic process GO:0006732 75 74 0,000 0,43132038 0,43629169 ! ribonucleotide biosynthetic process GO:0009260 75 75 0,000 0,43566527 0,44044492 ! purine ribonucleotide metabolic process GO:0009150 75 75 0,000 0,43566527 0,44020345 ! cellular metal ion homeostasis GO:0006875 77 77 0,000 0,44425761 0,44863932 ! microtubule-based movement GO:0007018 82 78 0,000 0,44850553 0,4526811 ! positive regulation of protein kinase cascade GO:0010740 79 78 0,000 0,44850553 0,45243332 ! metal ion homeostasis GO:0055065 78 78 0,000 0,44850553 0,45218582 ! glycoprotein biosynthetic process GO:0009101 80 80 0,000 0,45690605 0,46040342 ! lipid catabolic process GO:0016042 82 81 0,000 0,46105912 0,46433441 ! ribonucleotide metabolic process GO:0009259 83 83 0,000 0,46927204 0,47234755 ! ncRNA processing GO:0034470 83 83 0,000 0,46927204 0,47208972 ! organophosphate metabolic process GO:0019637 87 86 0,000 0,48136175 0,48398784 GO:0006644|phospholipid metabolic process, ! hexose metabolic process GO:0019318 87 86 0,000 0,48136175 0,48372394 ! purine nucleotide biosynthetic process GO:0006164 88 88 0,000 0,48927107 0,49140413 ! chemotaxis GO:0006935 90 89 0,000 0,49318124 0,49506156 GO:0042330|taxis, ! regulation of Ras protein signal transduction GO:0046578 90 90 0,000 0,49706205 0,49868555 ! visual perception GO:0007601 93 92 0,000 0,50473644 0,50610949 GO:0050953|sensory perception of light stimulus, ! fatty acid metabolic process GO:0006631 93 92 0,000 0,50473644 0,50583429 ! cofactor metabolic process GO:0051186 95 94 0,000 0,51229594 0,5131312 ! endocytosis GO:0006897 99 98 0,000 0,527077 0,5276496 GO:0010324|membrane invagination, ! regulation of system process GO:0044057 98 98 0,000 0,527077 0,52736314 ! response to other organism GO:0051707 101 100 0,000 0,53430187 0,53430187