pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6695-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! indolalkylamine biosynthetic process GO:0046219 7 5 3,000 4,763E-09 1,146E-05 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! indolalkylamine metabolic process GO:0006586 17 11 3,000 3,062E-07 3,684E-04 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of fibroblast proliferation GO:0048145 52 27 4,000 3,83E-07 3,072E-04 ! positive regulation of glycolysis GO:0045821 14 5 2,000 1,722E-06 1,036E-03 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 4,000 5,966E-06 2,871E-03 ! prostate gland development GO:0030850 13 7 2,000 5,976E-06 2,396E-03 ! regulation of protein export from nucleus GO:0046825 10 7 2,000 5,976E-06 2,054E-03 ! positive regulation of fibroblast proliferation GO:0048146 43 24 3,000 9,314E-06 2,801E-03 ! ER overload response GO:0006983 12 8 2,000 9,522E-06 2,545E-03 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 2,000 9,522E-06 2,291E-03 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 2,000 9,522E-06 2,083E-03 ! insulin receptor signaling pathway GO:0008286 64 26 3,000 1,299E-05 2,604E-03 ! positive regulation of glucose metabolic process GO:0010907 18 9 2,000 1,422E-05 2,632E-03 ! regulation of glycolysis GO:0006110 21 9 2,000 1,422E-05 2,444E-03 ! interphase of mitotic cell cycle GO:0051329 209 95 5,000 1,643E-05 2,635E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 4,000 1,734E-05 2,607E-03 ! positive regulation of cell migration GO:0030335 126 57 4,000 1,734E-05 2,454E-03 ! interphase GO:0051325 213 98 5,000 1,962E-05 2,623E-03 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 2,000 2,024E-05 2,562E-03 GO:0043470|regulation of carbohydrate catabolic process, ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 2,000 2,024E-05 2,434E-03 ! cell cycle arrest GO:0007050 213 100 5,000 2,202E-05 2,523E-03 ! cell junction assembly GO:0034329 78 30 3,000 2,34E-05 2,559E-03 ! regulation of homeostatic process GO:0032844 134 62 4,000 2,62E-05 2,741E-03 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 2,000 2,771E-05 2,778E-03 ! positive regulation of endothelial cell proliferation GO:0001938 22 11 2,000 2,771E-05 2,667E-03 ! positive regulation of catabolic process GO:0009896 64 32 3,000 3,043E-05 2,816E-03 ! positive regulation of cell motion GO:0051272 146 64 4,000 3,059E-05 2,726E-03 ! positive regulation of cellular catabolic process GO:0031331 31 12 2,000 3,679E-05 3,162E-03 ! biogenic amine biosynthetic process GO:0042401 62 34 3,000 3,891E-05 3,228E-03 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 2,000 4,763E-05 3,82E-03 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of monooxygenase activity GO:0032768 33 13 2,000 4,763E-05 3,697E-03 ! cell junction organization GO:0034330 86 36 3,000 4,899E-05 3,683E-03 ! hormone biosynthetic process GO:0042446 57 36 3,000 4,899E-05 3,572E-03 ! cellular response to insulin stimulus GO:0032869 82 37 3,000 5,469E-05 3,87E-03 ! regulation of erythrocyte differentiation GO:0045646 44 14 2,000 6,037E-05 4,15E-03 ! release of cytochrome c from mitochondria GO:0001836 30 14 2,000 6,037E-05 4,035E-03 ! carbohydrate homeostasis GO:0033500 53 38 3,000 6,086E-05 3,957E-03 GO:0042593|glucose homeostasis, ! rhythmic process GO:0048511 128 75 4,000 6,589E-05 4,172E-03 ! epithelial to mesenchymal transition GO:0001837 28 15 2,000 7,516E-05 4,637E-03 ! regulation of intracellular protein transport GO:0033157 80 42 3,000 9,068E-05 5,454E-03 ! neuron migration GO:0001764 79 42 3,000 9,068E-05 5,321E-03 ! regulation of glucose metabolic process GO:0010906 28 16 2,000 9,212E-05 5,277E-03 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 2,000 9,212E-05 5,154E-03 ! positive regulation of neuron apoptosis GO:0043525 32 16 2,000 9,212E-05 5,037E-03 ! regulation of epithelial cell proliferation GO:0050678 111 43 3,000 9,955E-05 5,322E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 2,000 1,114E-04 5,827E-03 ! induction of apoptosis by intracellular signals GO:0008629 93 45 3,000 1,191E-04 6,099E-03 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 3,000 1,299E-04 6,512E-03 ! regulation of gene-specific transcription GO:0032583 96 46 3,000 1,299E-04 6,379E-03 ! response to insulin stimulus GO:0032868 95 46 3,000 1,299E-04 6,252E-03 ! cell-substrate junction assembly GO:0007044 54 18 2,000 1,331E-04 6,281E-03 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 2,000 1,331E-04 6,16E-03 ! peptide cross-linking GO:0018149 37 19 2,000 1,574E-04 7,147E-03 ! positive regulation of MAP kinase activity GO:0043406 160 93 4,000 1,829E-04 8,151E-03 ! regulation of carbohydrate metabolic process GO:0006109 38 20 2,000 1,845E-04 8,069E-03 GO:0010675|regulation of cellular carbohydrate metabolic process, ! apoptotic mitochondrial changes GO:0008637 41 20 2,000 1,845E-04 7,925E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 2,000 1,845E-04 7,786E-03 ! regulation of angiogenesis GO:0045765 114 52 3,000 2,1E-04 8,71E-03 ! negative regulation of intracellular transport GO:0032387 41 21 2,000 2,143E-04 8,74E-03 ! hormone metabolic process GO:0042445 157 97 4,000 2,228E-04 8,934E-03 ! response to UV GO:0009411 104 53 3,000 2,261E-04 8,919E-03 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 3,000 2,431E-04 9,436E-03 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 2,000 2,471E-04 9,438E-03 ! positive regulation of cell adhesion GO:0045785 56 23 2,000 2,83E-04 0,01064037 ! regulation of intracellular transport GO:0032386 101 57 3,000 2,998E-04 0,0110956 ! hemoglobin biosynthetic process GO:0042541 7 5 1,000 3,096E-04 0,01128535 ! negative regulation of bone resorption GO:0045779 10 5 1,000 3,096E-04 0,01111692 ! cell adhesion mediated by integrin GO:0033627 8 5 1,000 3,096E-04 0,01095343 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 1,000 3,096E-04 0,01079469 ! negative regulation of survival gene product expression GO:0008634 8 5 1,000 3,096E-04 0,01064048 ! mRNA transcription GO:0009299 9 5 1,000 3,096E-04 0,01049061 ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 3,096E-04 0,01034491 ! meiotic chromosome segregation GO:0045132 7 5 1,000 3,096E-04 0,0102032 ! positive regulation of chemokine production GO:0032722 8 5 1,000 3,096E-04 0,01006532 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 1,000 3,096E-04 9,931E-03 ! regulation of cellular catabolic process GO:0031329 52 24 2,000 3,221E-04 0,01019823 ! regulation of oxidoreductase activity GO:0051341 46 24 2,000 3,221E-04 0,01006579 ! protein tetramerization GO:0051262 52 24 2,000 3,221E-04 9,937E-03 ! response to endoplasmic reticulum stress GO:0034976 43 25 2,000 3,646E-04 0,01110297 ! protein amino acid autophosphorylation GO:0046777 141 60 3,000 3,652E-04 0,01098467 ! response to peptide hormone stimulus GO:0043434 122 61 3,000 3,892E-04 0,01155996 ! regulation of endothelial cell proliferation GO:0001936 57 26 2,000 4,104E-04 0,01204228 ! regulation of chromosome organization GO:0033044 42 27 2,000 4,598E-04 0,01332933 ! regulation of hormone biosynthetic process GO:0046885 10 6 1,000 4,626E-04 0,01325149 ! male meiosis GO:0007140 7 6 1,000 4,626E-04 0,01309559 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 1,000 4,626E-04 0,01294332 ! embryonic hemopoiesis GO:0035162 14 6 1,000 4,626E-04 0,01279454 ! activation of MAPKKK activity GO:0000185 12 6 1,000 4,626E-04 0,01264915 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 1,000 4,626E-04 0,01250702 ! male sex determination GO:0030238 15 6 1,000 4,626E-04 0,01236806 ! establishment of spindle localization GO:0051293 12 6 1,000 4,626E-04 0,01223214 GO:0051653|spindle localization, ! negative regulation of neuroblast proliferation GO:0007406 21 6 1,000 4,626E-04 0,01209919 ! negative regulation of osteoblast differentiation GO:0045668 17 6 1,000 4,626E-04 0,01196909 ! ER-nuclear signaling pathway GO:0006984 48 28 2,000 5,129E-04 0,01312769 ! cellular hormone metabolic process GO:0034754 113 67 3,000 5,569E-04 0,01410366 ! lung development GO:0030324 144 67 3,000 5,569E-04 0,01395674 ! cellular iron ion homeostasis GO:0006879 51 29 2,000 5,697E-04 0,01413127 ! cellular response to extracellular stimulus GO:0031668 48 29 2,000 5,697E-04 0,01398708 ! regulation of helicase activity GO:0051095 15 7 1,000 6,453E-04 0,01568307 ! neuron adhesion GO:0007158 12 7 1,000 6,453E-04 0,01552624 ! N-terminal protein amino acid acetylation GO:0006474 13 7 1,000 6,453E-04 0,01537252 ! mRNA stabilization GO:0048255 18 7 1,000 6,453E-04 0,0152218 GO:0043489|RNA stabilization, ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 1,000 6,453E-04 0,01507402 ! wound healing, spreading of epidermal cells GO:0035313 14 7 1,000 6,453E-04 0,01492908 ! G1 DNA damage checkpoint GO:0031571 21 7 1,000 6,453E-04 0,0147869 ! B cell lineage commitment GO:0002326 21 7 1,000 6,453E-04 0,0146474 ! positive regulation of monooxygenase activity GO:0032770 12 7 1,000 6,453E-04 0,01451051 ! T cell lineage commitment GO:0002360 16 7 1,000 6,453E-04 0,01437615 ! oxygen homeostasis GO:0032364 12 7 1,000 6,453E-04 0,01424426 ! response to tumor cell GO:0002347 13 7 1,000 6,453E-04 0,01411476 ! regulation of respiratory burst GO:0060263 11 7 1,000 6,453E-04 0,0139876 ! axonal fasciculation GO:0007413 18 7 1,000 6,453E-04 0,01386271 ! respiratory tube development GO:0030323 150 70 3,000 6,575E-04 0,01400011 ! B cell activation GO:0042113 160 71 3,000 6,938E-04 0,01464203 ! iron ion homeostasis GO:0055072 54 31 2,000 6,951E-04 0,0145426 ! respiratory system development GO:0060541 153 72 3,000 7,314E-04 0,01516996 ! learning or memory GO:0007611 147 73 3,000 7,704E-04 0,01584323 ! positive regulation of gene-specific transcription GO:0043193 65 33 2,000 8,368E-04 0,01706201 ! negative regulation of protein transport GO:0051224 69 33 2,000 8,368E-04 0,01691864 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 8,572E-04 0,01718774 ! neurotransmitter uptake GO:0001504 14 8 1,000 8,572E-04 0,01704569 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 1,000 8,572E-04 0,01690598 ! T-helper 1 type immune response GO:0042088 12 8 1,000 8,572E-04 0,01676853 ! hemoglobin metabolic process GO:0020027 13 8 1,000 8,572E-04 0,0166333 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 8,572E-04 0,01650023 ! positive regulation of endothelial cell migration GO:0010595 19 8 1,000 8,572E-04 0,01636928 ! regulation of vascular permeability GO:0043114 12 8 1,000 8,572E-04 0,01624039 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 1,000 8,572E-04 0,01611351 ! regulation of catabolic process GO:0009894 161 76 3,000 8,964E-04 0,01671857 ! placenta development GO:0001890 53 34 2,000 9,14E-04 0,01691612 ! protein oligomerization GO:0051259 139 78 3,000 9,88E-04 0,01814586 ! regulation of developmental growth GO:0048638 15 9 1,000 1,098E-03 0,02001549 ! induction of positive chemotaxis GO:0050930 15 9 1,000 1,098E-03 0,019865 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 1,000 1,098E-03 0,01971676 ! microtubule bundle formation GO:0001578 21 9 1,000 1,098E-03 0,01957071 ! middle ear morphogenesis GO:0042474 14 9 1,000 1,098E-03 0,0194268 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 1,000 1,098E-03 0,019285 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 1,000 1,098E-03 0,01914525 ! motor axon guidance GO:0008045 16 9 1,000 1,098E-03 0,01900752 ! protein heterooligomerization GO:0051291 16 9 1,000 1,098E-03 0,01887175 ! gas homeostasis GO:0033483 16 9 1,000 1,098E-03 0,01873791 ! positive regulation of erythrocyte differentiation GO:0045648 29 9 1,000 1,098E-03 0,01860595 ! regulation of telomere maintenance GO:0032204 14 9 1,000 1,098E-03 0,01847584 ! response to hypoxia GO:0001666 171 81 3,000 1,137E-03 0,01900507 ! tissue remodeling GO:0048771 76 37 2,000 1,172E-03 0,01945145 ! cellular response to hormone stimulus GO:0032870 167 82 3,000 1,191E-03 0,0196207 ! response to oxygen levels GO:0070482 176 83 3,000 1,245E-03 0,02038532 ! negative regulation of growth GO:0045926 155 84 3,000 1,302E-03 0,02116797 ! learning GO:0007612 77 39 2,000 1,368E-03 0,02208232 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 1,000 1,368E-03 0,0219359 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 1,000 1,368E-03 0,02179063 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 1,368E-03 0,02164727 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 1,000 1,368E-03 0,02150578 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 1,000 1,368E-03 0,02136613 ! lung alveolus development GO:0048286 26 10 1,000 1,368E-03 0,02122829 ! negative regulation of striated muscle development GO:0045843 19 10 1,000 1,368E-03 0,02109221 ! epithelial cell development GO:0002064 20 10 1,000 1,368E-03 0,02095786 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 1,000 1,368E-03 0,02082522 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 1,000 1,368E-03 0,02069424 ! regulation of bone resorption GO:0045124 25 10 1,000 1,368E-03 0,0205649 ! positive regulation of leukocyte migration GO:0002687 25 10 1,000 1,368E-03 0,02043717 ! localization within membrane GO:0051668 20 10 1,000 1,368E-03 0,02031102 ! amine biosynthetic process GO:0009309 138 86 3,000 1,421E-03 0,02097039 ! mitochondrion organization GO:0007005 148 86 3,000 1,421E-03 0,02084252 ! mesenchymal cell development GO:0014031 87 40 2,000 1,472E-03 0,02146953 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! regulation of protein transport GO:0051223 154 87 3,000 1,483E-03 0,02149042 GO:0070201|regulation of establishment of protein localization, ! gland development GO:0048732 206 88 3,000 1,547E-03 0,0222822 ! negative regulation of muscle development GO:0048635 20 11 1,000 1,665E-03 0,0238498 ! detection of mechanical stimulus GO:0050982 22 11 1,000 1,665E-03 0,02370868 ! blood vessel remodeling GO:0001974 29 11 1,000 1,665E-03 0,02356921 ! peptide or protein amino-terminal blocking GO:0018409 21 11 1,000 1,665E-03 0,02343138 ! regulation of intracellular pH GO:0051453 19 11 1,000 1,665E-03 0,02329515 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 1,000 1,665E-03 0,0231605 ! nitric oxide metabolic process GO:0046209 15 11 1,000 1,665E-03 0,02302739 GO:0006809|nitric oxide biosynthetic process, ! regulation of leukocyte migration GO:0002685 26 11 1,000 1,665E-03 0,02289581 ! T cell receptor signaling pathway GO:0050852 23 11 1,000 1,665E-03 0,02276572 ! regulation of embryonic development GO:0045995 27 11 1,000 1,665E-03 0,0226371 ! regulation of myeloid cell differentiation GO:0045637 98 42 2,000 1,697E-03 0,02293547 ! biogenic amine metabolic process GO:0006576 155 94 3,000 1,971E-03 0,02648853 ! virus-host interaction GO:0019048 29 12 1,000 1,991E-03 0,02661341 ! regulation of B cell proliferation GO:0030888 20 12 1,000 1,991E-03 0,02646638 ! regulation of positive chemotaxis GO:0050926 19 12 1,000 1,991E-03 0,02632096 GO:0050927|positive regulation of positive chemotaxis, ! focal adhesion formation GO:0048041 35 12 1,000 1,991E-03 0,02617713 ! L-glutamate transport GO:0015813 22 12 1,000 1,991E-03 0,02603486 GO:0015800|acidic amino acid transport, ! histone acetylation GO:0016573 26 12 1,000 1,991E-03 0,02589413 ! regulation of hormone metabolic process GO:0032350 26 12 1,000 1,991E-03 0,02575492 ! peptidyl-lysine modification GO:0018205 21 12 1,000 1,991E-03 0,02561719 ! negative regulation of mast cell proliferation GO:0070667 23 12 1,000 1,991E-03 0,02548093 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 1,000 1,991E-03 0,02534611 ! regulation of DNA metabolic process GO:0051052 178 97 3,000 2,21E-03 0,02798814 ! regulation of protein localization GO:0032880 176 97 3,000 2,21E-03 0,02784161 ! regulation of chemokine production GO:0032642 18 13 1,000 2,344E-03 0,02937792 ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 1,000 2,344E-03 0,02922571 ! endocrine pancreas development GO:0031018 22 13 1,000 2,344E-03 0,02907506 ! cell-cell junction assembly GO:0007043 27 13 1,000 2,344E-03 0,02892596 ! response to X-ray GO:0010165 25 13 1,000 2,344E-03 0,02877837 ! regulation of cellular pH GO:0030641 22 13 1,000 2,344E-03 0,02863229 ! regulation of mRNA stability GO:0043488 31 13 1,000 2,344E-03 0,02848768 ! embryonic placenta development GO:0001892 23 13 1,000 2,344E-03 0,02834453 ! cytoplasmic sequestering of protein GO:0051220 24 13 1,000 2,344E-03 0,02820281 ! positive regulation of cell cycle GO:0045787 89 48 2,000 2,494E-03 0,02985761 ! activation of caspase activity GO:0006919 84 48 2,000 2,494E-03 0,0297098 ! regulation of mast cell proliferation GO:0070666 81 48 2,000 2,494E-03 0,02956344 ! N-terminal protein amino acid modification GO:0031365 27 14 1,000 2,725E-03 0,03213944 ! regulation of mRNA processing GO:0050684 24 14 1,000 2,725E-03 0,03198266 ! L-amino acid transport GO:0015807 30 14 1,000 2,725E-03 0,0318274 ! bone mineralization GO:0030282 17 14 1,000 2,725E-03 0,03167365 ! negative regulation of protein import into nucleus GO:0042308 30 14 1,000 2,725E-03 0,03152137 ! response to gamma radiation GO:0010332 28 14 1,000 2,725E-03 0,03137055 ! regulation of RNA stability GO:0043487 32 14 1,000 2,725E-03 0,03122117 ! regulation of leukocyte proliferation GO:0070663 88 51 2,000 2,967E-03 0,03382783 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of cell shape GO:0008360 125 51 2,000 2,967E-03 0,03366826 ! positive regulation of cell size GO:0045793 27 15 1,000 3,133E-03 0,03538643 ! negative regulation of bone remodeling GO:0046851 33 15 1,000 3,133E-03 0,03522107 ! heterophilic cell adhesion GO:0007157 39 15 1,000 3,133E-03 0,03505725 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 1,000 3,133E-03 0,03489495 ! G1/S transition checkpoint GO:0031575 40 15 1,000 3,133E-03 0,03473414 ! positive regulation of oxidoreductase activity GO:0051353 22 15 1,000 3,133E-03 0,03457481 ! synaptic transmission, cholinergic GO:0007271 24 15 1,000 3,133E-03 0,03441694 ! muscle maintenance GO:0046716 26 15 1,000 3,133E-03 0,03426049 ! regulation of translational initiation GO:0006446 82 53 2,000 3,31E-03 0,03603495 ! regulation of neuron apoptosis GO:0043523 100 53 2,000 3,31E-03 0,03587263 ! cell recognition GO:0008037 85 54 2,000 3,49E-03 0,03765815 ! G1 phase of mitotic cell cycle GO:0000080 35 16 1,000 3,567E-03 0,0383143 ! embryonic forelimb morphogenesis GO:0035115 28 16 1,000 3,567E-03 0,03814402 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 1,000 3,567E-03 0,03797524 ! activation of MAPKK activity GO:0000186 35 16 1,000 3,567E-03 0,03780795 ! negative regulation of microtubule depolymerization GO:0007026 46 16 1,000 3,567E-03 0,03764212 GO:0031114|regulation of microtubule depolymerization, ! DNA replication initiation GO:0006270 27 16 1,000 3,567E-03 0,03747775 ! neuron recognition GO:0008038 35 16 1,000 3,567E-03 0,0373148 ! negative regulation of tissue remodeling GO:0034104 36 16 1,000 3,567E-03 0,03715327 ! biomineral formation GO:0031214 20 16 1,000 3,567E-03 0,03699312 ! negative regulation of leukocyte proliferation GO:0070664 31 16 1,000 3,567E-03 0,03683435 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of caspase activity GO:0043280 95 55 2,000 3,677E-03 0,03780348 GO:0010952|positive regulation of peptidase activity, ! heart morphogenesis GO:0003007 97 55 2,000 3,677E-03 0,03764261 ! regulation of DNA replication GO:0006275 101 56 2,000 3,869E-03 0,03944325 ! negative regulation of cell cycle process GO:0010948 32 17 1,000 4,028E-03 0,04089024 ! heart looping GO:0001947 30 17 1,000 4,028E-03 0,04071844 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 1,000 4,028E-03 0,04054807 ! regulation of survival gene product expression GO:0045884 33 17 1,000 4,028E-03 0,04037912 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 1,000 4,028E-03 0,04021157 ! neural crest cell migration GO:0001755 37 17 1,000 4,028E-03 0,0400454 ! negative regulation of homeostatic process GO:0032845 33 17 1,000 4,028E-03 0,03988061 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 1,000 4,028E-03 0,03971716 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 1,000 4,028E-03 0,03955505 ! regulation of bone remodeling GO:0046850 137 57 2,000 4,067E-03 0,03977921 ! regulation of tissue remodeling GO:0034103 140 58 2,000 4,272E-03 0,04160883 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 4,515E-03 0,04379969 ! protein amino acid ADP-ribosylation GO:0006471 33 18 1,000 4,515E-03 0,04362379 ! memory GO:0007613 31 18 1,000 4,515E-03 0,04344929 ! response to retinoic acid GO:0032526 26 18 1,000 4,515E-03 0,04327619 ! peptidyl-serine phosphorylation GO:0018105 38 18 1,000 4,515E-03 0,04310446 ! positive regulation of translation GO:0045727 30 19 1,000 5,027E-03 0,04780901 ! positive regulation of angiogenesis GO:0045766 44 19 1,000 5,027E-03 0,04762078 ! lipid phosphorylation GO:0046834 35 19 1,000 5,027E-03 0,04743404 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 1,000 5,027E-03 0,04724875 ! response to vitamin A GO:0033189 27 19 1,000 5,027E-03 0,0470649 ! actin filament bundle formation GO:0051017 42 19 1,000 5,027E-03 0,04688248 ! plasma membrane fusion GO:0045026 28 19 1,000 5,027E-03 0,04670146 ! regulation of endothelial cell migration GO:0010594 44 19 1,000 5,027E-03 0,04652184 ! forelimb morphogenesis GO:0035136 32 19 1,000 5,027E-03 0,0463436 ! neuromuscular junction development GO:0007528 34 19 1,000 5,027E-03 0,04616671 ! G1 phase GO:0051318 40 19 1,000 5,027E-03 0,04599118 ! cell-cell junction organization GO:0045216 35 19 1,000 5,027E-03 0,04581697 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 1,000 5,027E-03 0,04564407 ! regulation of mitosis GO:0007088 105 63 2,000 5,386E-03 0,04872015 GO:0051783|regulation of nuclear division, ! protein amino acid acetylation GO:0006473 39 20 1,000 5,565E-03 0,05015105 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 1,000 5,565E-03 0,04996392 ! response to vitamin GO:0033273 31 20 1,000 5,565E-03 0,04977818 ! response to alkaloid GO:0043279 38 20 1,000 5,565E-03 0,04959382 ! pancreas development GO:0031016 35 20 1,000 5,565E-03 0,04941082 ! cellular response to starvation GO:0009267 33 20 1,000 5,565E-03 0,04922916 ! negative regulation of angiogenesis GO:0016525 45 20 1,000 5,565E-03 0,04904883 ! peptidyl-serine modification GO:0018209 43 20 1,000 5,565E-03 0,04886982 ! negative regulation of T cell activation GO:0050868 40 20 1,000 5,565E-03 0,04869211 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 1,000 5,565E-03 0,04851569 ! hindlimb morphogenesis GO:0035137 43 21 1,000 6,129E-03 0,05323307 ! axis specification GO:0009798 38 21 1,000 6,129E-03 0,05304159 ! cell structure disassembly during apoptosis GO:0006921 30 21 1,000 6,129E-03 0,05285147 ! cell aging GO:0007569 44 21 1,000 6,129E-03 0,05266272 ! cytolysis GO:0019835 24 21 1,000 6,129E-03 0,05247531 ! positive regulation of locomotion GO:0040017 39 21 1,000 6,129E-03 0,05228923 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 1,000 6,129E-03 0,05210446 ! negative regulation of protein kinase activity GO:0006469 130 67 2,000 6,393E-03 0,05415767 ! negative regulation of cell growth GO:0030308 132 67 2,000 6,393E-03 0,05396764 ! activation of MAPK activity GO:0000187 115 67 2,000 6,393E-03 0,05377894 ! adaptive immune response GO:0002250 119 67 2,000 6,393E-03 0,05359156 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 2,000 6,393E-03 0,05340548 ! negative regulation of kinase activity GO:0033673 131 68 2,000 6,661E-03 0,05545066 ! positive regulation of protein catabolic process GO:0045732 38 22 1,000 6,717E-03 0,0557264 ! regulation of chemotaxis GO:0050920 40 22 1,000 6,717E-03 0,0555349 ! glutamate signaling pathway GO:0007215 41 22 1,000 6,717E-03 0,05534472 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 1,000 6,717E-03 0,05515583 ! apoptotic nuclear changes GO:0030262 32 22 1,000 6,717E-03 0,05496822 ! positive regulation of intracellular transport GO:0032388 37 22 1,000 6,717E-03 0,05478189 ! positive regulation of B cell activation GO:0050871 38 22 1,000 6,717E-03 0,05459681 ! activation of JUN kinase activity GO:0007257 42 22 1,000 6,717E-03 0,05441299 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 1,000 6,717E-03 0,05423039 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 1,000 6,717E-03 0,05404902 ! cell cycle checkpoint GO:0000075 137 69 2,000 6,935E-03 0,05561855 ! negative regulation of cell size GO:0045792 134 69 2,000 6,935E-03 0,05543377 ! urogenital system development GO:0001655 137 69 2,000 6,935E-03 0,05525022 ! positive regulation of DNA replication GO:0045740 43 23 1,000 7,33E-03 0,05820103 ! leukocyte adhesion GO:0007159 50 23 1,000 7,33E-03 0,05800958 ! regulation of cell-matrix adhesion GO:0001952 78 23 1,000 7,33E-03 0,05781938 GO:0010810|regulation of cell-substrate adhesion, ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 1,000 7,33E-03 0,05763043 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 1,000 7,33E-03 0,05744271 ! sex determination GO:0007530 47 23 1,000 7,33E-03 0,05725621 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 1,000 7,33E-03 0,05707091 ! platelet activation GO:0030168 37 23 1,000 7,33E-03 0,05688681 ! reproductive structure development GO:0048608 113 71 2,000 7,504E-03 0,05805198 ! acute inflammatory response GO:0002526 113 72 2,000 7,798E-03 0,06013661 ! regulation of caspase activity GO:0043281 122 72 2,000 7,798E-03 0,05994448 ! negative regulation of transferase activity GO:0051348 140 72 2,000 7,798E-03 0,05975357 ! protein import into nucleus, translocation GO:0000060 46 24 1,000 7,967E-03 0,0608496 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 1,000 7,967E-03 0,06065704 ! regulation of behavior GO:0050795 43 24 1,000 7,967E-03 0,06046569 ! negative regulation of phosphorylation GO:0042326 47 24 1,000 7,967E-03 0,06027555 ! axon guidance GO:0007411 139 73 2,000 8,099E-03 0,06108869 ! meiosis GO:0007126 121 74 2,000 8,407E-03 0,0632133 GO:0051327|M phase of meiotic cell cycle, ! regulation of endopeptidase activity GO:0052548 125 74 2,000 8,407E-03 0,06301638 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 1,000 8,628E-03 0,06446616 ! myelination GO:0042552 45 25 1,000 8,628E-03 0,06426657 ! vasculogenesis GO:0001570 46 25 1,000 8,628E-03 0,06406822 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 1,000 8,628E-03 0,06387108 ! negative regulation of DNA replication GO:0008156 42 25 1,000 8,628E-03 0,06367516 ! response to starvation GO:0042594 42 25 1,000 8,628E-03 0,06348044 ! neural crest cell development GO:0014032 54 25 1,000 8,628E-03 0,0632869 GO:0014033|neural crest cell differentiation, ! negative regulation of cell development GO:0010721 73 25 1,000 8,628E-03 0,06309454 GO:0050768|negative regulation of neurogenesis, ! interaction with host GO:0051701 62 25 1,000 8,628E-03 0,06290334 ! somitogenesis GO:0001756 43 25 1,000 8,628E-03 0,0627133 ! cellular response to nutrient levels GO:0031669 41 25 1,000 8,628E-03 0,0625244 ! neural tube closure GO:0001843 49 25 1,000 8,628E-03 0,06233664 GO:0060606|tube closure, ! liver development GO:0001889 53 25 1,000 8,628E-03 0,06215001 ! meiotic cell cycle GO:0051321 122 75 2,000 8,722E-03 0,06264358 ! tube lumen formation GO:0035148 50 26 1,000 9,312E-03 0,0666835 ! regulation of transcription factor import into nucleus GO:0042990 54 26 1,000 9,312E-03 0,06648562 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 1,000 9,312E-03 0,06628892 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 1,000 9,312E-03 0,06609338 GO:0045936|negative regulation of phosphate metabolic process, ! cellular response to oxidative stress GO:0034599 39 26 1,000 9,312E-03 0,06589899 ! positive regulation of nuclear division GO:0051785 40 26 1,000 9,312E-03 0,06570573 GO:0045840|positive regulation of mitosis, ! regulation of osteoblast differentiation GO:0045667 65 26 1,000 9,312E-03 0,06551361 ! positive regulation of JUN kinase activity GO:0043507 51 26 1,000 9,312E-03 0,06532261 ! negative regulation of organelle organization GO:0010639 161 78 2,000 9,708E-03 0,06789711 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 1,000 0,01002062 0,0698829 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 1,000 0,01002062 0,06968093 ! protein amino acid acylation GO:0043543 55 27 1,000 0,01002062 0,06948012 ! mitochondrial membrane organization GO:0007006 57 27 1,000 0,01002062 0,06928046 ! response to toxin GO:0009636 47 27 1,000 0,01002062 0,06908195 ! primary neural tube formation GO:0014020 51 27 1,000 0,01002062 0,06888457 ! base-excision repair GO:0006284 41 27 1,000 0,01002062 0,06868832 ! negative regulation of lymphocyte activation GO:0051250 53 27 1,000 0,01002062 0,06849318 ! regulation of peptidase activity GO:0052547 134 79 2,000 0,01004994 0,06849906 ! circadian rhythm GO:0007623 50 28 1,000 0,01075198 0,07307701 ! dendrite development GO:0016358 59 28 1,000 0,01075198 0,07287116 ! peptidyl-tyrosine modification GO:0018212 50 28 1,000 0,01075198 0,07266647 ! regulation of JUN kinase activity GO:0043506 58 28 1,000 0,01075198 0,07246292 ! cell-substrate adhesion GO:0031589 171 81 2,000 0,01075541 0,07228356 ! regulation of pH GO:0006885 43 29 1,000 0,01150622 0,07711412 ! complement activation, classical pathway GO:0006958 48 29 1,000 0,01150622 0,07689991 ! immune response-activating signal transduction GO:0002757 47 29 1,000 0,01150622 0,07668689 GO:0002764|immune response-regulating signal transduction, ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 1,000 0,01150622 0,07647505 ! tissue homeostasis GO:0001894 48 29 1,000 0,01150622 0,07626438 GO:0048871|multicellular organismal homeostasis, ! negative regulation of transport GO:0051051 153 84 2,000 0,01186616 0,07843402 ! response to unfolded protein GO:0006986 131 85 2,000 0,01225051 0,0807527 ! acute-phase response GO:0006953 49 30 1,000 0,01228306 0,08074605 ! ensheathment of neurons GO:0007272 57 30 1,000 0,01228306 0,08052603 GO:0008366|axon ensheathment, ! negative regulation of leukocyte activation GO:0002695 56 30 1,000 0,01228306 0,08030721 ! regulation of B cell activation GO:0050864 50 30 1,000 0,01228306 0,08008957 ! response to heat GO:0009408 50 30 1,000 0,01228306 0,07987312 ! tube morphogenesis GO:0035239 176 86 2,000 0,01264195 0,08198528 ! collagen metabolic process GO:0032963 45 31 1,000 0,01308223 0,08461252 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 1,000 0,01308223 0,08438567 ! regulation of DNA binding GO:0051101 155 88 2,000 0,01344616 0,08650126 ! regulation of cell morphogenesis GO:0022604 215 89 2,000 0,01385897 0,08891916 ! regulation of cell adhesion GO:0030155 212 89 2,000 0,01385897 0,08868267 ! spindle organization GO:0007051 46 32 1,000 0,01390346 0,08873137 ! response to ionizing radiation GO:0010212 65 32 1,000 0,01390346 0,08849663 ! response to mechanical stimulus GO:0009612 57 32 1,000 0,01390346 0,08826313 ! regulation of protein import into nucleus GO:0042306 63 32 1,000 0,01390346 0,08803086 ! peripheral nervous system development GO:0007422 64 32 1,000 0,01390346 0,0877998 ! ossification GO:0001503 188 90 2,000 0,01427893 0,08993485 ! regulation of cell cycle process GO:0010564 149 90 2,000 0,01427893 0,08970003 ! bone development GO:0060348 189 91 2,000 0,01470606 0,09214268 ! response to protein stimulus GO:0051789 149 91 2,000 0,01470606 0,09190335 ! DNA damage checkpoint GO:0000077 71 33 1,000 0,01474647 0,09191712 ! xenobiotic metabolic process GO:0006805 51 34 1,000 0,015611 0,09705444 ! regulation of striated muscle tissue development GO:0016202 69 34 1,000 0,015611 0,09680429 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 1,000 0,015611 0,09655544 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 1,000 0,015611 0,09630786 ! regulation of muscle development GO:0048634 70 35 1,000 0,01649678 0,10151217 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 1,000 0,01649678 0,10125321 ! negative regulation of DNA metabolic process GO:0051053 61 35 1,000 0,01649678 0,10099557 ! negative regulation of hydrolase activity GO:0051346 62 35 1,000 0,01649678 0,10073923 ! calcium-mediated signaling GO:0019722 62 35 1,000 0,01649678 0,1004842 ! regulation of microtubule-based process GO:0032886 78 35 1,000 0,01649678 0,10023045 ! neural tube formation GO:0001841 67 35 1,000 0,01649678 0,09997798 ! positive regulation of immune response GO:0050778 156 96 2,000 0,01694973 0,10246493 ! mitotic sister chromatid segregation GO:0000070 57 36 1,000 0,01740356 0,10494475 ! maintenance of protein location in cell GO:0032507 86 36 1,000 0,01740356 0,10468238 ! DNA integrity checkpoint GO:0031570 75 36 1,000 0,01740356 0,10442133 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 1,000 0,01740356 0,10416158 ! androgen receptor signaling pathway GO:0030521 74 36 1,000 0,01740356 0,10390311 ! embryonic organ development GO:0048568 57 36 1,000 0,01740356 0,10364592 ! negative regulation of cell activation GO:0050866 65 36 1,000 0,01740356 0,10339001 ! meiosis I GO:0007127 65 37 1,000 0,01833106 0,10863183 ! sister chromatid segregation GO:0000819 58 37 1,000 0,01833106 0,10836493 ! organic anion transport GO:0015711 68 37 1,000 0,01833106 0,10809933 ! monovalent inorganic cation homeostasis GO:0055067 58 37 1,000 0,01833106 0,10783502 ! negative regulation of DNA binding GO:0043392 68 37 1,000 0,01833106 0,10757201 ! glycogen metabolic process GO:0005977 61 37 1,000 0,01833106 0,10731028 ! skeletal muscle tissue development GO:0007519 186 99 2,000 0,01838271 0,10735144 GO:0060538|skeletal muscle organ development, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 1,000 0,01927903 0,1123132 GO:0006956|complement activation, ! positive regulation of DNA metabolic process GO:0051054 72 38 1,000 0,01927903 0,11204191 ! mitotic cell cycle checkpoint GO:0007093 76 38 1,000 0,01927903 0,11177193 ! nucleus organization GO:0006997 67 38 1,000 0,01927903 0,11150325 ! embryonic epithelial tube formation GO:0001838 72 38 1,000 0,01927903 0,11123585 ! positive regulation of leukocyte proliferation GO:0070665 62 38 1,000 0,01927903 0,11096974 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! glucan metabolic process GO:0044042 62 38 1,000 0,01927903 0,11070489 GO:0006073|cellular glucan metabolic process, ! mammary gland development GO:0030879 86 39 1,000 0,02024722 0,11598765 ! ear morphogenesis GO:0042471 60 39 1,000 0,02024722 0,11571215 ! segmentation GO:0035282 67 39 1,000 0,02024722 0,11543795 ! regulation of action potential in neuron GO:0019228 73 39 1,000 0,02024722 0,11516505 ! Rho protein signal transduction GO:0007266 74 39 1,000 0,02024722 0,11489343 ! response to xenobiotic stimulus GO:0009410 57 39 1,000 0,02024722 0,11462309 ! feeding behavior GO:0007631 59 40 1,000 0,02123537 0,11993499 ! negative regulation of binding GO:0051100 72 40 1,000 0,02123537 0,11965411 ! multicellular organismal metabolic process GO:0044236 57 40 1,000 0,02123537 0,11937455 ! maintenance of protein location GO:0045185 91 40 1,000 0,02123537 0,11909628 ! cytokinesis GO:0000910 72 40 1,000 0,02123537 0,11881932 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 1,000 0,02224323 0,12416988 ! gliogenesis GO:0042063 88 41 1,000 0,02224323 0,12388245 ! regulation of T cell proliferation GO:0042129 71 41 1,000 0,02224323 0,12359635 ! T cell differentiation GO:0030217 81 41 1,000 0,02224323 0,12331157 ! keratinocyte differentiation GO:0030216 62 41 1,000 0,02224323 0,12302809 ! regulation of T cell differentiation GO:0045580 70 41 1,000 0,02224323 0,12274592 ! dorsal/ventral pattern formation GO:0009953 68 41 1,000 0,02224323 0,12246503 ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 0,02327055 0,12782866 GO:0090047|positive regulation of transcription regulator activity, ! negative regulation of protein complex disassembly GO:0043242 101 42 1,000 0,02327055 0,12753748 ! epithelial cell differentiation GO:0030855 79 43 1,000 0,02431709 0,13297027 ! energy reserve metabolic process GO:0006112 74 43 1,000 0,02431709 0,13266875 ! glucose transport GO:0015758 65 43 1,000 0,02431709 0,13236859 ! positive regulation of response to external stimulus GO:0032103 77 43 1,000 0,02431709 0,13206979 ! neural tube development GO:0021915 77 43 1,000 0,02431709 0,13177234 ! hexose transport GO:0008645 67 44 1,000 0,02538259 0,13723711 GO:0015749|monosaccharide transport, ! double-strand break repair GO:0006302 81 44 1,000 0,02538259 0,13692941 ! B cell differentiation GO:0030183 107 44 1,000 0,02538259 0,13662308 ! maintenance of location in cell GO:0051651 97 44 1,000 0,02538259 0,13631811 ! detection of stimulus involved in sensory perception GO:0050906 66 45 1,000 0,02646682 0,14182442 ! branching morphogenesis of a tube GO:0048754 97 45 1,000 0,02646682 0,14150925 ! cell growth GO:0016049 84 45 1,000 0,02646682 0,14119549 ! epidermal cell differentiation GO:0009913 68 46 1,000 0,02756953 0,14675284 ! pigmentation GO:0043473 100 46 1,000 0,02756953 0,14642889 ! positive regulation of protein transport GO:0051222 72 46 1,000 0,02756953 0,14610636 ! negative regulation of cell migration GO:0030336 115 46 1,000 0,02756953 0,14578524 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,02774594 0,14639636 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,02774594 0,14607602 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,02774594 0,14575708 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,02774594 0,14543952 ! neuron fate determination GO:0048664 7 5 0,000 0,02774594 0,14512335 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02774594 0,14480855 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,02774594 0,14449511 ! polyol transport GO:0015791 12 5 0,000 0,02774594 0,14418303 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,02774594 0,14387229 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,02774594 0,14356288 ! response to superoxide GO:0000303 10 5 0,000 0,02774594 0,14325481 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,02774594 0,14294805 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,02774594 0,14264261 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,02774594 0,14233847 ! female meiosis GO:0007143 7 5 0,000 0,02774594 0,14203562 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,02774594 0,14173406 ! cobalt ion transport GO:0006824 11 5 0,000 0,02774594 0,14143377 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,02774594 0,14113476 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,02774594 0,14083701 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,02774594 0,14054051 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,02774594 0,14024525 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,02774594 0,13995124 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,02774594 0,13965845 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,02774594 0,13936689 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,02774594 0,13907654 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,02774594 0,1387874 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,02774594 0,13849946 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02774594 0,13821271 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,02774594 0,13792715 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,02774594 0,13764276 ! negative chemotaxis GO:0050919 14 5 0,000 0,02774594 0,13735955 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,02774594 0,1370775 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,02774594 0,1367966 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,02774594 0,13651685 ! behavioral response to pain GO:0048266 9 5 0,000 0,02774594 0,13623825 ! clathrin coat assembly GO:0048268 14 5 0,000 0,02774594 0,13596078 ! Notch receptor processing GO:0007220 8 5 0,000 0,02774594 0,13568443 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02774594 0,13540921 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,02774594 0,1351351 ! micturition GO:0060073 9 5 0,000 0,02774594 0,1348621 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,02774594 0,1345902 ! copulation GO:0007620 9 5 0,000 0,02774594 0,1343194 ! glial cell fate commitment GO:0021781 13 5 0,000 0,02774594 0,13404968 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,02774594 0,13378104 ! spermidine metabolic process GO:0008216 7 5 0,000 0,02774594 0,13351348 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,02774594 0,13324699 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,02774594 0,13298156 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,02774594 0,13271718 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,02774594 0,13245385 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,02774594 0,13219157 ! grooming behavior GO:0007625 6 5 0,000 0,02774594 0,13193032 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,02774594 0,1316701 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,02774594 0,13141091 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02774594 0,13115273 ! response to protozoan GO:0001562 10 5 0,000 0,02774594 0,13089557 ! lymph vessel development GO:0001945 10 5 0,000 0,02774594 0,13063941 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,02774594 0,13038426 ! endochondral ossification GO:0001958 16 5 0,000 0,02774594 0,1301301 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,02774594 0,12987693 ! parathyroid gland development GO:0060017 13 5 0,000 0,02774594 0,12962474 ! anagen GO:0042640 6 5 0,000 0,02774594 0,12937353 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,02774594 0,12912329 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,02774594 0,12887402 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,02774594 0,1286257 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,02774594 0,12837835 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,02774594 0,12813194 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,02774594 0,12788648 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,02774594 0,12764195 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,02774594 0,12739836 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,02774594 0,1271557 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,02774594 0,12691396 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,02774594 0,12667313 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,02774594 0,12643322 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,02774594 0,12619422 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,02774594 0,12595611 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,02774594 0,12571891 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,02774594 0,1254826 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,02774594 0,12524717 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,02774594 0,12501262 ! histidine catabolic process GO:0006548 6 5 0,000 0,02774594 0,12477895 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,02774594 0,12454616 ! microvillus organization GO:0032528 7 5 0,000 0,02774594 0,12431423 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 0,02774594 0,12408316 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,02774594 0,12385295 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,02774594 0,12362359 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,02774594 0,12339508 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,02774594 0,12316742 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,02774594 0,12294059 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,02774594 0,1227146 ! polyol catabolic process GO:0046174 7 5 0,000 0,02774594 0,12248943 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,02774594 0,12226509 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,02774594 0,12204157 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,02774594 0,12181887 ! muscle cell migration GO:0014812 8 5 0,000 0,02774594 0,12159698 ! mitochondrial fission GO:0000266 8 5 0,000 0,02774594 0,12137589 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,02774594 0,12115561 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,02774594 0,12093612 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,02774594 0,12071743 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,02774594 0,12049953 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,02774594 0,12028242 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,02774594 0,12006608 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,02774594 0,11985052 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,02774594 0,11963574 ! response to food GO:0032094 6 5 0,000 0,02774594 0,11942172 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,02774594 0,11920847 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,02774594 0,11899597 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,02774594 0,11878424 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02774594 0,11857325 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,02774594 0,11836302 ! forebrain neuron development GO:0021884 13 5 0,000 0,02774594 0,11815352 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,02774594 0,11794477 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,02774594 0,11773676 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,02774594 0,11752947 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02774594 0,11732292 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,02774594 0,11711709 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,02774594 0,11691198 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02774594 0,11670759 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,02774594 0,11650391 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,02774594 0,11630094 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,02774594 0,11609868 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,02774594 0,11589712 ! basic amino acid transport GO:0015802 11 5 0,000 0,02774594 0,11569626 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,02774594 0,11549609 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,02774594 0,11529662 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,02774594 0,11509783 ! depyrimidination GO:0045008 10 5 0,000 0,02774594 0,11489973 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,02774594 0,1147023 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02774594 0,11450556 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,02774594 0,11430949 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,02774594 0,11411409 GO:0006882|cellular zinc ion homeostasis, ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,02774594 0,11391935 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02774594 0,11372528 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,02774594 0,11353187 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,02774594 0,11333912 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,02774594 0,11314702 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,02774594 0,11295557 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,02774594 0,11276476 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02774594 0,1125746 ! response to arsenic GO:0046685 10 5 0,000 0,02774594 0,11238509 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,02774594 0,1121962 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,02774594 0,11200795 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,02774594 0,11182034 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,02774594 0,11163335 ! response to cadmium ion GO:0046686 7 5 0,000 0,02774594 0,11144698 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,02774594 0,11126123 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,02774594 0,11107611 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,02774594 0,1108916 ! decidualization GO:0046697 11 5 0,000 0,02774594 0,1107077 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,02774594 0,11052441 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,02774594 0,11034172 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,02774594 0,11015964 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,02774594 0,10997816 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,02774594 0,10979727 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,02774594 0,10961698 ! neural tube patterning GO:0021532 7 5 0,000 0,02774594 0,10943728 ! embryonic cleavage GO:0040016 6 5 0,000 0,02774594 0,10925817 ! peroxisome fission GO:0016559 5 5 0,000 0,02774594 0,10907964 ! histone demethylation GO:0016577 10 5 0,000 0,02774594 0,1089017 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,02774594 0,10872433 ! mitotic recombination GO:0006312 9 5 0,000 0,02774594 0,10854755 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,02774594 0,10837133 ! metaphase plate congression GO:0051310 7 5 0,000 0,02774594 0,10819569 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02774594 0,10802062 GO:0032374|regulation of cholesterol transport, ! enteric nervous system development GO:0048484 8 5 0,000 0,02774594 0,10784611 ! lymphocyte costimulation GO:0031294 6 5 0,000 0,02774594 0,10767216 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,02774594 0,10749878 ! muscle cell proliferation GO:0033002 11 5 0,000 0,02774594 0,10732595 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,02774594 0,10715368 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,02774594 0,10698196 ! plasminogen activation GO:0031639 5 5 0,000 0,02774594 0,10681079 ! B cell homeostasis GO:0001782 13 5 0,000 0,02774594 0,10664016 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,02774594 0,10647008 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,02774594 0,10630054 ! metaphase GO:0051323 8 5 0,000 0,02774594 0,10613154 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,02774594 0,10596308 ! cellular response to nutrient GO:0031670 8 5 0,000 0,02774594 0,10579515 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,02774594 0,10562775 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,02774594 0,10546089 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,02774594 0,10529454 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,02774594 0,10512873 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,02774594 0,10496343 ! response to redox state GO:0051775 5 5 0,000 0,02774594 0,10479865 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,02774594 0,10463439 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,02774594 0,10447064 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,02774594 0,10430741 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,02774594 0,10414468 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02774594 0,10398246 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,02774594 0,10382075 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02774594 0,10365954 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,02774594 0,10349882 ! striatum development GO:0021756 9 5 0,000 0,02774594 0,10333861 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,02774594 0,10317889 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,02774594 0,10301966 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,02774594 0,10286093 ! glial cell migration GO:0008347 11 5 0,000 0,02774594 0,10270268 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,02774594 0,10254492 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,02774594 0,10238764 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,02774594 0,10223084 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,02774594 0,10207453 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,02774594 0,10191869 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,02774594 0,10176332 ! neuroprotection GO:0043526 6 5 0,000 0,02774594 0,10160843 ! neural plate development GO:0001840 8 5 0,000 0,02774594 0,10145401 ! regulation of sensory perception GO:0051931 7 5 0,000 0,02774594 0,10130006 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,02774594 0,10114658 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,02774594 0,10099356 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,02774594 0,100841 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,02774594 0,1006889 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,02774594 0,10053726 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,02774594 0,10038608 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,02774594 0,10023535 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,02774594 0,10008507 ! spindle assembly GO:0051225 6 5 0,000 0,02774594 0,09993524 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,02774594 0,09978586 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,02774594 0,09963693 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,02774594 0,09948844 ! drug metabolic process GO:0017144 6 5 0,000 0,02774594 0,09934039 ! stem cell division GO:0017145 11 5 0,000 0,02774594 0,09919278 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,02774594 0,09904561 ! organ regeneration GO:0031100 7 5 0,000 0,02774594 0,09889888 ! carnitine metabolic process GO:0009437 7 5 0,000 0,02774594 0,09875258 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,02774594 0,09860671 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,02774594 0,09846127 ! positive regulation of DNA binding GO:0043388 73 47 1,000 0,02869048 0,10166319 ! vascular process in circulatory system GO:0003018 80 47 1,000 0,02869048 0,10151368 ! JNK cascade GO:0007254 91 47 1,000 0,02869048 0,10136462 ! regulation of JNK cascade GO:0046328 94 47 1,000 0,02869048 0,10121599 ! protein homooligomerization GO:0051260 76 47 1,000 0,02869048 0,10106779 ! mitochondrial transport GO:0006839 82 48 1,000 0,02982945 0,10492639 ! cellular component disassembly GO:0022411 86 48 1,000 0,02982945 0,10477321 ! morphogenesis of embryonic epithelium GO:0016331 91 48 1,000 0,02982945 0,10462048 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 1,000 0,02982945 0,10446819 ! regulation of lymphocyte differentiation GO:0045619 81 48 1,000 0,02982945 0,10431635 ! regulation of action potential GO:0001508 95 49 1,000 0,03098618 0,10820429 ! regulation of protein complex disassembly GO:0043244 113 49 1,000 0,03098618 0,10804747 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 1,000 0,03098618 0,10789111 ! response to temperature stimulus GO:0009266 76 49 1,000 0,03098618 0,10773519 ! endocrine system development GO:0035270 104 49 1,000 0,03098618 0,10757973 ! DNA-dependent DNA replication GO:0006261 74 49 1,000 0,03098618 0,10742472 ! immunoglobulin mediated immune response GO:0016064 83 49 1,000 0,03098618 0,10727015 GO:0019724|B cell mediated immunity, ! detection of abiotic stimulus GO:0009582 74 49 1,000 0,03098618 0,10711603 ! regulation of ossification GO:0030278 117 50 1,000 0,03216046 0,11101587 ! histone modification GO:0016570 91 50 1,000 0,03216046 0,11085682 ! negative regulation of immune system process GO:0002683 95 50 1,000 0,03216046 0,11069823 ! positive regulation of cytokine production GO:0001819 86 50 1,000 0,03216046 0,11054009 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,0332026 0,11395929 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,0332026 0,11379696 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,0332026 0,11363508 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,0332026 0,11347367 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,0332026 0,11331271 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,0332026 0,11315222 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,0332026 0,11299217 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,0332026 0,11283258 ! sleep GO:0030431 13 6 0,000 0,0332026 0,11267343 ! response to oxygen radical GO:0000305 11 6 0,000 0,0332026 0,11251474 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,0332026 0,11235649 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,0332026 0,11219869 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,0332026 0,11204132 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,0332026 0,1118844 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,0332026 0,11172792 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,0332026 0,11157188 ! forebrain regionalization GO:0021871 8 6 0,000 0,0332026 0,11141627 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,0332026 0,11126109 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,0332026 0,11110635 ! response to zinc ion GO:0010043 9 6 0,000 0,0332026 0,11095203 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,0332026 0,11079815 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,0332026 0,11064469 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,0332026 0,11049165 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,0332026 0,11033904 ! malate metabolic process GO:0006108 11 6 0,000 0,0332026 0,11018685 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,0332026 0,11003507 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,0332026 0,10988372 ! protein refolding GO:0042026 15 6 0,000 0,0332026 0,10973278 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,0332026 0,10958225 ! opsonization GO:0008228 8 6 0,000 0,0332026 0,10943214 ! mating behavior GO:0007617 7 6 0,000 0,0332026 0,10928244 ! neuron remodeling GO:0016322 15 6 0,000 0,0332026 0,10913315 ! erythrocyte maturation GO:0043249 7 6 0,000 0,0332026 0,10898426 ! equilibrioception GO:0050957 14 6 0,000 0,0332026 0,10883578 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,0332026 0,10868771 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,0332026 0,10854003 ! photoreceptor cell development GO:0042461 10 6 0,000 0,0332026 0,10839276 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,0332026 0,10824589 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,0332026 0,10809941 ! response to interferon-gamma GO:0034341 15 6 0,000 0,0332026 0,10795333 ! toxin metabolic process GO:0009404 11 6 0,000 0,0332026 0,10780764 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,0332026 0,10766235 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,0332026 0,10751745 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,0332026 0,10737294 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,0332026 0,10722881 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,0332026 0,10708507 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,0332026 0,10694172 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,0332026 0,10679875 ! thymic T cell selection GO:0045061 12 6 0,000 0,0332026 0,10665616 ! protein lipoylation GO:0009249 10 6 0,000 0,0332026 0,10651395 ! cysteine metabolic process GO:0006534 10 6 0,000 0,0332026 0,10637212 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,0332026 0,10623067 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,0332026 0,10608959 ! glutamate catabolic process GO:0006538 10 6 0,000 0,0332026 0,10594889 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,0332026 0,10580856 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,0332026 0,1056686 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,0332026 0,10552901 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,0332026 0,10538979 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,0332026 0,10525094 ! hyperosmotic response GO:0006972 9 6 0,000 0,0332026 0,10511245 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,0332026 0,10497433 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,0332026 0,10483657 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,0332026 0,10469917 ! urea metabolic process GO:0019627 7 6 0,000 0,0332026 0,10456213 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,0332026 0,10442544 ! neutrophil activation GO:0042119 8 6 0,000 0,0332026 0,10428912 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,0332026 0,10415315 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,0332026 0,10401753 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,0332026 0,10388227 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,0332026 0,10374736 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,0332026 0,10361279 ! neuron apoptosis GO:0051402 9 6 0,000 0,0332026 0,10347858 ! nucleoside salvage GO:0043174 9 6 0,000 0,0332026 0,10334471 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,0332026 0,10321119 ! T cell mediated immunity GO:0002456 16 6 0,000 0,0332026 0,10307802 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,0332026 0,10294519 GO:0010543|regulation of platelet activation, ! carnitine transport GO:0015879 10 6 0,000 0,0332026 0,10281269 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,0332026 0,10268054 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,0332026 0,10254873 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,0332026 0,10241726 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,0332026 0,10228613 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,0332026 0,10215532 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,0332026 0,10202486 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,0332026 0,10189472 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,0332026 0,10176492 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,0332026 0,10163545 ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,0332026 0,10150631 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,0332026 0,10137749 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,0332026 0,101249 ! neural nucleus development GO:0048857 14 6 0,000 0,0332026 0,10112084 ! response to UV-C GO:0010225 11 6 0,000 0,0332026 0,100993 ! astrocyte development GO:0014002 15 6 0,000 0,0332026 0,10086548 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,0332026 0,10073829 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,0332026 0,10061142 ! interaction with symbiont GO:0051702 13 6 0,000 0,0332026 0,10048486 ! regulation of dendrite development GO:0050773 16 6 0,000 0,0332026 0,10035862 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,0332026 0,1002327 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,0332026 0,1001071 ! response to copper ion GO:0046688 10 6 0,000 0,0332026 0,09998181 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,0332026 0,09985683 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,0332026 0,09973216 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,0332026 0,09960781 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,0332026 0,09948377 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,0332026 0,09936003 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,0332026 0,0992366 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,0332026 0,09911348 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,0332026 0,09899066 ! hair follicle maturation GO:0048820 7 6 0,000 0,0332026 0,09886815 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,0332026 0,09874594 ! Schwann cell development GO:0014044 15 6 0,000 0,0332026 0,09862403 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,0332026 0,09850242 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,0332026 0,09838111 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,0332026 0,0982601 ! subpallium development GO:0021544 10 6 0,000 0,0332026 0,09813939 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,0332026 0,09801897 ! histone ubiquitination GO:0016574 8 6 0,000 0,0332026 0,09789885 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,0332026 0,09777903 ! maintenance of organ identity GO:0048496 9 6 0,000 0,0332026 0,09765949 ! G2 phase GO:0051319 16 6 0,000 0,0332026 0,09754025 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,0332026 0,0974213 ! establishment of planar polarity GO:0001736 7 6 0,000 0,0332026 0,09730264 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,0332026 0,09718426 ! membrane to membrane docking GO:0022614 14 6 0,000 0,0332026 0,09706618 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,0332026 0,09694838 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,0332026 0,09683087 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,0332026 0,09671364 ! receptor internalization GO:0031623 10 6 0,000 0,0332026 0,09659669 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,0332026 0,09648003 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,0332026 0,09636365 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,0332026 0,09624755 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,0332026 0,09613173 ! protein deubiquitination GO:0016579 14 6 0,000 0,0332026 0,09601618 ! protein destabilization GO:0031648 9 6 0,000 0,0332026 0,09590092 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,0332026 0,09578593 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,0332026 0,09567121 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,0332026 0,09555677 ! progesterone metabolic process GO:0042448 10 6 0,000 0,0332026 0,09544261 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,0332026 0,09532872 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,0332026 0,09521509 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,0332026 0,09510174 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,0332026 0,09498866 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,0332026 0,09487585 ! determination of adult lifespan GO:0008340 15 6 0,000 0,0332026 0,0947633 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,0332026 0,09465102 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,0332026 0,09453901 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,0332026 0,09442726 ! catecholamine transport GO:0051937 9 6 0,000 0,0332026 0,09431578 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,0332026 0,09420456 ! sensory cilium assembly GO:0035058 10 6 0,000 0,0332026 0,0940936 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,0332026 0,0939829 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,0332026 0,09387246 ! maternal placenta development GO:0001893 12 6 0,000 0,0332026 0,09376228 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,0332026 0,09365236 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,0332026 0,0935427 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,0332026 0,09343329 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,0332026 0,09332414 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,0332026 0,09321524 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,0332026 0,0931066 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,0332026 0,09299821 ! positive regulation of binding GO:0051099 78 51 1,000 0,03335204 0,09330816 ! epithelial tube morphogenesis GO:0060562 98 51 1,000 0,03335204 0,09319979 ! membrane fusion GO:0006944 110 52 1,000 0,03456071 0,09646528 ! positive regulation of growth GO:0045927 90 52 1,000 0,03456071 0,0963535 ! covalent chromatin modification GO:0016569 101 52 1,000 0,03456071 0,09624198 ! morphogenesis of a branching structure GO:0001763 111 52 1,000 0,03456071 0,09613071 ! cartilage development GO:0051216 90 52 1,000 0,03456071 0,09601971 ! synapse organization GO:0050808 85 52 1,000 0,03456071 0,09590896 ! cell maturation GO:0048469 100 53 1,000 0,03578623 0,09919547 ! activation of phospholipase C activity GO:0007202 103 54 1,000 0,03702838 0,10252046 GO:0010863|positive regulation of phospholipase C activity, ! negative regulation of cytoskeleton organization GO:0051494 124 54 1,000 0,03702838 0,10240262 ! cellular polysaccharide metabolic process GO:0044264 86 55 1,000 0,03828694 0,10576162 ! positive regulation of phospholipase activity GO:0010518 104 55 1,000 0,03828694 0,10564033 ! regulation of protein catabolic process GO:0042176 116 55 1,000 0,03828694 0,10551932 ! aging GO:0007568 103 55 1,000 0,03828694 0,10539859 ! negative regulation of cell motion GO:0051271 134 55 1,000 0,03828694 0,10527813 ! tRNA transcription GO:0009304 14 7 0,000 0,03862882 0,10609696 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,03862882 0,10597598 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,03862882 0,10585528 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,03862882 0,10573485 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,03862882 0,1056147 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,03862882 0,10549482 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,03862882 0,10537521 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,03862882 0,10525587 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,03862882 0,10513681 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,03862882 0,10501801 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,03862882 0,10489948 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,03862882 0,10478121 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,03862882 0,10466322 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,03862882 0,10454549 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,03862882 0,10442802 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,03862882 0,10431082 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 0,03862882 0,10419388 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,03862882 0,1040772 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,03862882 0,10396078 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,03862882 0,10384462 ! glycolipid transport GO:0046836 10 7 0,000 0,03862882 0,10372872 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,03862882 0,10361308 GO:0051923|sulfation, ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,03862882 0,1034977 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,03862882 0,10338258 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,03862882 0,10326771 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,03862882 0,10315309 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,03862882 0,10303873 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,03862882 0,10292463 ! pericardium development GO:0060039 14 7 0,000 0,03862882 0,10281077 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,03862882 0,10269717 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,03862882 0,10258382 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,03862882 0,10247071 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,03862882 0,10235786 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,03862882 0,10224526 ! lipoprotein transport GO:0042953 14 7 0,000 0,03862882 0,1021329 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,03862882 0,10202079 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,03862882 0,10190892 ! rhythmic behavior GO:0007622 15 7 0,000 0,03862882 0,1017973 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,03862882 0,10168593 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,03862882 0,10157479 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,03862882 0,10146391 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,03862882 0,10135326 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,03862882 0,10124285 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,03862882 0,10113268 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,03862882 0,10102276 ! mechanosensory behavior GO:0007638 14 7 0,000 0,03862882 0,10091307 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,03862882 0,10080362 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,03862882 0,10069441 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,03862882 0,10058543 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,03862882 0,10047669 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,03862882 0,10036818 ! spinal cord patterning GO:0021511 13 7 0,000 0,03862882 0,10025991 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,03862882 0,10015187 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,03862882 0,10004407 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,03862882 0,09993649 ! adrenal gland development GO:0030325 17 7 0,000 0,03862882 0,09982915 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,03862882 0,09972204 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,03862882 0,09961515 ! ovulation GO:0030728 9 7 0,000 0,03862882 0,0995085 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,03862882 0,09940207 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,03862882 0,09929587 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,03862882 0,0991899 ! microtubule nucleation GO:0007020 20 7 0,000 0,03862882 0,09908415 ! proline biosynthetic process GO:0006561 10 7 0,000 0,03862882 0,09897863 ! thyroid hormone generation GO:0006590 13 7 0,000 0,03862882 0,09887334 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,03862882 0,09876826 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,03862882 0,09866342 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,03862882 0,09855879 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,03862882 0,09845438 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,03862882 0,0983502 ! galactose metabolic process GO:0006012 13 7 0,000 0,03862882 0,09824623 ! vesicle fusion GO:0006906 17 7 0,000 0,03862882 0,09814249 ! response to dietary excess GO:0002021 8 7 0,000 0,03862882 0,09803896 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,03862882 0,09793566 ! intracellular pH reduction GO:0051452 11 7 0,000 0,03862882 0,09783257 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,03862882 0,09772969 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,03862882 0,09762703 ! organ growth GO:0035265 15 7 0,000 0,03862882 0,09752459 ! purine salvage GO:0043101 10 7 0,000 0,03862882 0,09742237 ! nucleoside transport GO:0015858 8 7 0,000 0,03862882 0,09732035 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,03862882 0,09721855 ! parturition GO:0007567 14 7 0,000 0,03862882 0,09711697 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,03862882 0,09701559 ! rRNA modification GO:0000154 14 7 0,000 0,03862882 0,09691443 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,03862882 0,09681348 ! spindle checkpoint GO:0031577 15 7 0,000 0,03862882 0,09671273 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,03862882 0,0966122 ! macrophage differentiation GO:0030225 11 7 0,000 0,03862882 0,09651188 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,03862882 0,09641176 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,03862882 0,09631185 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,03862882 0,09621215 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,03862882 0,09611265 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,03862882 0,09601336 ! fibrinolysis GO:0042730 10 7 0,000 0,03862882 0,09591428 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,03862882 0,0958154 ! eating behavior GO:0042755 7 7 0,000 0,03862882 0,09571672 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,03862882 0,09561825 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,03862882 0,09551998 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,03862882 0,09542191 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,03862882 0,09532404 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,03862882 0,09522637 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,03862882 0,0951289 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,03862882 0,09503163 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,03862882 0,09493456 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,03862882 0,09483769 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,03862882 0,09474102 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,03862882 0,09464454 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,03862882 0,09454826 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,03862882 0,09445217 ! regulation of meiosis GO:0040020 12 7 0,000 0,03862882 0,09435628 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,03862882 0,09426059 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,03862882 0,09416508 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,03862882 0,09406977 ! transcription termination GO:0006353 13 7 0,000 0,03862882 0,09397466 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,03862882 0,09387973 ! anaphase GO:0051322 17 7 0,000 0,03862882 0,093785 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,03862882 0,09369046 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,03862882 0,09359611 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,03862882 0,09350195 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,03862882 0,09340798 ! diuresis GO:0030146 12 7 0,000 0,03862882 0,09331419 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,03862882 0,0932206 ! thiamin metabolic process GO:0006772 7 7 0,000 0,03862882 0,09312719 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,03862882 0,09303397 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,03862882 0,09294094 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,03862882 0,09284809 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,03862882 0,09275543 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,03862882 0,09266295 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,03862882 0,09257065 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,03862882 0,09247854 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,03862882 0,09238662 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,03862882 0,09229487 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,03862882 0,09220331 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,03862882 0,09211193 ! lymph node development GO:0048535 10 7 0,000 0,03862882 0,09202073 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,03862882 0,09192971 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,03862882 0,09183887 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,03862882 0,09174821 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,03862882 0,09165773 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,03862882 0,09156743 ! adult feeding behavior GO:0008343 9 7 0,000 0,03862882 0,0914773 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,03862882 0,09138735 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,03862882 0,09129758 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,03862882 0,09120799 ! muscle adaptation GO:0043500 14 7 0,000 0,03862882 0,09111857 ! embryonic heart tube development GO:0035050 10 7 0,000 0,03862882 0,09102932 ! retina homeostasis GO:0001895 12 7 0,000 0,03862882 0,09094025 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,03862882 0,09085136 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,03862882 0,09076263 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,03862882 0,09067409 ! protein prenylation GO:0018342 18 7 0,000 0,03862882 0,09058571 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,03862882 0,0904975 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,03862882 0,09040947 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,03862882 0,09032161 ! skeletal muscle fiber development GO:0048741 111 56 1,000 0,03956168 0,09241301 ! nucleotide-excision repair GO:0006289 83 56 1,000 0,03956168 0,09232337 ! positive regulation of organelle organization GO:0010638 100 56 1,000 0,03956168 0,09223391 ! muscle fiber development GO:0048747 112 57 1,000 0,04085239 0,09515086 ! lipid modification GO:0030258 97 57 1,000 0,04085239 0,09505884 ! regulation of phospholipase activity GO:0010517 106 57 1,000 0,04085239 0,09496699 ! maintenance of location GO:0051235 118 57 1,000 0,04085239 0,09487533 ! positive regulation of lipase activity GO:0060193 108 58 1,000 0,04215884 0,09781502 ! skeletal system morphogenesis GO:0048705 105 59 1,000 0,04348084 0,10078506 ! DNA catabolic process GO:0006308 86 59 1,000 0,04348084 0,10068806 ! integrin-mediated signaling pathway GO:0007229 135 59 1,000 0,04348084 0,10059124 ! establishment of organelle localization GO:0051656 109 59 1,000 0,04348084 0,10049461 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,04402476 0,10165409 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,04402476 0,10155663 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,04402476 0,10145936 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,04402476 0,10136226 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,04402476 0,10126536 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,04402476 0,10116864 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,04402476 0,10107211 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,04402476 0,10097575 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,04402476 0,10087959 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,04402476 0,1007836 ! meiotic prophase I GO:0007128 13 8 0,000 0,04402476 0,1006878 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,04402476 0,10059218 ! oligopeptide transport GO:0006857 15 8 0,000 0,04402476 0,10049674 ! UTP metabolic process GO:0046051 8 8 0,000 0,04402476 0,10040149 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,04402476 0,10030641 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,04402476 0,10021151 GO:0046457|prostanoid biosynthetic process, ! macrophage chemotaxis GO:0048246 12 8 0,000 0,04402476 0,10011679 ! succinate metabolic process GO:0006105 14 8 0,000 0,04402476 0,10002225 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,04402476 0,09992789 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,04402476 0,09983371 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,04402476 0,09973971 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,04402476 0,09964588 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,04402476 0,09955222 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,04402476 0,09945875 ! reflex GO:0060004 16 8 0,000 0,04402476 0,09936545 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,04402476 0,09927232 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,04402476 0,09917937 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,04402476 0,09908659 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,04402476 0,09899399 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,04402476 0,09890156 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,04402476 0,0988093 ! pigment granule organization GO:0048753 16 8 0,000 0,04402476 0,09871721 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,04402476 0,0986253 ! astrocyte differentiation GO:0048708 18 8 0,000 0,04402476 0,09853355 ! histidine metabolic process GO:0006547 16 8 0,000 0,04402476 0,09844198 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,04402476 0,09835057 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,04402476 0,09825934 ! glycine catabolic process GO:0006546 13 8 0,000 0,04402476 0,09816827 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,04402476 0,09807738 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,04402476 0,09798665 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,04402476 0,09789609 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,04402476 0,09780569 ! melanin metabolic process GO:0006582 15 8 0,000 0,04402476 0,09771547 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,04402476 0,09762541 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,04402476 0,09753551 ! macrophage activation GO:0042116 12 8 0,000 0,04402476 0,09744578 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,04402476 0,09735622 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,04402476 0,09726682 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,04402476 0,09717758 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,04402476 0,09708851 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,04402476 0,0969996 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,04402476 0,09691086 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,04402476 0,09682227 ! osteoblast development GO:0002076 16 8 0,000 0,04402476 0,09673385 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,04402476 0,09664559 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,04402476 0,09655749 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,04402476 0,09646955 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,04402476 0,09638177 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,04402476 0,09629415 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,04402476 0,09620669 ! response to UV-B GO:0010224 16 8 0,000 0,04402476 0,09611939 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,04402476 0,09603225 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,04402476 0,09594526 ! intermediate filament organization GO:0045109 12 8 0,000 0,04402476 0,09585843 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,04402476 0,09577176 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,04402476 0,09568525 ! cellular extravasation GO:0045123 12 8 0,000 0,04402476 0,09559889 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,04402476 0,09551268 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,04402476 0,09542664 ! response to antibiotic GO:0046677 11 8 0,000 0,04402476 0,09534074 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,04402476 0,09525501 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,04402476 0,09516942 ! DNA topological change GO:0006265 12 8 0,000 0,04402476 0,09508399 ! response to tropane GO:0014073 15 8 0,000 0,04402476 0,09499871 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,04402476 0,09491359 ! melanosome transport GO:0032402 13 8 0,000 0,04402476 0,09482862 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,04402476 0,0947438 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,04402476 0,09465913 ! mast cell activation GO:0045576 14 8 0,000 0,04402476 0,09457461 ! multicellular organismal aging GO:0010259 18 8 0,000 0,04402476 0,09449025 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,04402476 0,09440603 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,04402476 0,09432197 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,04402476 0,09423805 ! nucleosome disassembly GO:0006337 14 8 0,000 0,04402476 0,09415428 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,04402476 0,09407066 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,04402476 0,09398719 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,04402476 0,09390387 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,04402476 0,0938207 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,04402476 0,09373767 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,04402476 0,09365479 ! intracellular lipid transport GO:0032365 13 8 0,000 0,04402476 0,09357206 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,04402476 0,09348947 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,04402476 0,09340703 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,04402476 0,09332473 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,04402476 0,09324258 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,04402476 0,09316057 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,04402476 0,09307871 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,04402476 0,09299699 ! hormone catabolic process GO:0042447 17 8 0,000 0,04402476 0,09291541 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,04402476 0,09283398 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,04402476 0,09275269 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,04402476 0,09267154 ! ATP catabolic process GO:0006200 11 8 0,000 0,04402476 0,09259053 ! blastocyst growth GO:0001832 19 8 0,000 0,04402476 0,09250967 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,04402476 0,09242894 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,04402476 0,09234836 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,04402476 0,09226792 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,04402476 0,09218761 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,04402476 0,09210745 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,04402476 0,09202743 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,04402476 0,09194754 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,04402476 0,09186779 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,04402476 0,09178819 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,04402476 0,09170872 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,04402476 0,09162938 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,04402476 0,09155019 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,04402476 0,09147113 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,04402476 0,09139221 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,04402476 0,09131342 GO:0000076|DNA replication checkpoint, ! NAD biosynthetic process GO:0009435 13 8 0,000 0,04402476 0,09123477 ! regulation of neurotransmitter levels GO:0001505 97 60 1,000 0,04481815 0,09279903 ! DNA damage response, signal transduction GO:0042770 128 60 1,000 0,04481815 0,09271923 ! mesoderm development GO:0007498 119 61 1,000 0,04617057 0,09543505 ! ear development GO:0043583 103 62 1,000 0,0475379 0,09817698 ! viral reproductive process GO:0022415 126 62 1,000 0,0475379 0,09809278 ! detection of external stimulus GO:0009581 91 63 1,000 0,04891992 0,10085803 ! steroid hormone receptor signaling pathway GO:0030518 129 63 1,000 0,04891992 0,10077168 ! axon extension GO:0048675 15 9 0,000 0,04939059 0,1016542 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,04939059 0,10156731 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,04939059 0,10148058 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,04939059 0,10139399 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,04939059 0,10130755 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,04939059 0,10122126 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,04939059 0,10113511 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,04939059 0,10104911 ! phosphate transport GO:0006817 19 9 0,000 0,04939059 0,10096326 ! reproductive behavior GO:0019098 19 9 0,000 0,04939059 0,10087755 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,04939059 0,10079199 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,04939059 0,10070657 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,04939059 0,1006213 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,04939059 0,10053617 ! GTP metabolic process GO:0046039 9 9 0,000 0,04939059 0,10045119 ! RNA methylation GO:0001510 15 9 0,000 0,04939059 0,10036635 ! elastic fiber assembly GO:0048251 15 9 0,000 0,04939059 0,10028165 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,04939059 0,1001971 ! artery development GO:0060840 24 9 0,000 0,04939059 0,10011269 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,04939059 0,10002842 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,04939059 0,09994429 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,04939059 0,0998603 ! chemosensory behavior GO:0007635 20 9 0,000 0,04939059 0,09977645 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,04939059 0,09969275 ! leukocyte degranulation GO:0043299 16 9 0,000 0,04939059 0,09960918 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,04939059 0,09952576 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,04939059 0,09944247 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,04939059 0,09935933 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,04939059 0,09927632 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,04939059 0,09919345 ! protein targeting to ER GO:0045047 22 9 0,000 0,04939059 0,09911072 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,04939059 0,09902813 ! T cell selection GO:0045058 23 9 0,000 0,04939059 0,09894568 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,04939059 0,09886336 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,04939059 0,09878118 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,04939059 0,09869913 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,04939059 0,09861723 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,04939059 0,09853545 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,04939059 0,09845382 ! mannose metabolic process GO:0006013 13 9 0,000 0,04939059 0,09837232 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,04939059 0,09829095 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,04939059 0,09820972 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,04939059 0,09812862 ! receptor clustering GO:0043113 18 9 0,000 0,04939059 0,09804765 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,04939059 0,09796682 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,04939059 0,09788613 ! ruffle organization GO:0031529 15 9 0,000 0,04939059 0,09780556 ! retinol metabolic process GO:0042572 18 9 0,000 0,04939059 0,09772513 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,04939059 0,09764483 ! behavioral fear response GO:0001662 22 9 0,000 0,04939059 0,09756466 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,04939059 0,09748462 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,04939059 0,09740472 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,04939059 0,09732494 GO:0030204|chondroitin sulfate metabolic process, ! oligodendrocyte development GO:0014003 10 9 0,000 0,04939059 0,0972453 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,04939059 0,09716579 ! segment specification GO:0007379 13 9 0,000 0,04939059 0,0970864 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,04939059 0,09700715 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,04939059 0,09692802 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,04939059 0,09684903 ! response to amine stimulus GO:0014075 13 9 0,000 0,04939059 0,09677016 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,04939059 0,09669142 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,04939059 0,09661281 ! erythrocyte development GO:0048821 15 9 0,000 0,04939059 0,09653433 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,04939059 0,09645597 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,04939059 0,09637774 ! renal water homeostasis GO:0003091 14 9 0,000 0,04939059 0,09629964 ! postreplication repair GO:0006301 22 9 0,000 0,04939059 0,09622167 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,04939059 0,09614382 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,04939059 0,09606609 ! icosanoid secretion GO:0032309 15 9 0,000 0,04939059 0,0959885 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,04939059 0,09591102 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,04939059 0,09583368 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,04939059 0,09575645 ! regulation of cell division GO:0051302 15 9 0,000 0,04939059 0,09567935 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,04939059 0,09560238 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,04939059 0,09552553 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,04939059 0,0954488 ! sterol catabolic process GO:0016127 11 9 0,000 0,04939059 0,0953722 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,04939059 0,09529572 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,04939059 0,09521936 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,04939059 0,09514312 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,04939059 0,09506701 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,04939059 0,09499101 ! musculoskeletal movement GO:0050881 14 9 0,000 0,04939059 0,09491514 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,04939059 0,09483939 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,04939059 0,09476376 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,04939059 0,09468825 ! purine base metabolic process GO:0006144 21 9 0,000 0,04939059 0,09461286 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,04939059 0,0945376 ! pigment granule transport GO:0051904 17 9 0,000 0,04939059 0,09446245 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,04939059 0,09438742 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,04939059 0,09431251 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,04939059 0,09423771 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,04939059 0,09416304 ! mitochondrion localization GO:0051646 15 9 0,000 0,04939059 0,09408849 ! lymphocyte mediated immunity GO:0002449 114 64 1,000 0,05031642 0,09577635 ! embryonic limb morphogenesis GO:0030326 125 65 1,000 0,05172721 0,09838393 GO:0035113|embryonic appendage morphogenesis, ! actin filament organization GO:0007015 148 66 1,000 0,05315208 0,10101414 ! developmental maturation GO:0021700 116 66 1,000 0,05315208 0,10093442 ! regulation of cellular response to stress GO:0080135 128 67 1,000 0,05459083 0,10358481 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 1,000 0,05459083 0,10350319 ! chromosome segregation GO:0007059 113 67 1,000 0,05459083 0,10342169 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,05472648 0,1035971 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,05472648 0,10351565 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,05472648 0,10343434 ! synapsis GO:0007129 13 10 0,000 0,05472648 0,10335315 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,05472648 0,10327209 ! N-glycan processing GO:0006491 20 10 0,000 0,05472648 0,10319115 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,05472648 0,10311034 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,05472648 0,10302966 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,05472648 0,10294911 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,05472648 0,10286868 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,05472648 0,10278838 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,05472648 0,1027082 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,05472648 0,10262814 ! androgen metabolic process GO:0008209 17 10 0,000 0,05472648 0,10254822 ! phospholipid efflux GO:0033700 16 10 0,000 0,05472648 0,10246841 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,05472648 0,10238873 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,05472648 0,10230918 ! pathogenesis GO:0009405 13 10 0,000 0,05472648 0,10222974 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,05472648 0,10215043 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,05472648 0,10207125 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,05472648 0,10199218 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,05472648 0,10191324 ! endoderm development GO:0007492 16 10 0,000 0,05472648 0,10183442 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,05472648 0,10175573 ! arginine catabolic process GO:0006527 13 10 0,000 0,05472648 0,10167715 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,05472648 0,1015987 ! proline metabolic process GO:0006560 13 10 0,000 0,05472648 0,10152036 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,05472648 0,10144215 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,05472648 0,10136406 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,05472648 0,10128608 ! V(D)J recombination GO:0033151 28 10 0,000 0,05472648 0,10120823 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,05472648 0,1011305 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,05472648 0,10105289 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,05472648 0,10097539 ! B cell proliferation GO:0042100 18 10 0,000 0,05472648 0,10089802 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,05472648 0,10082076 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,05472648 0,10074362 ! multicellular organism growth GO:0035264 18 10 0,000 0,05472648 0,1006666 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,05472648 0,10058969 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,05472648 0,10051291 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,05472648 0,10043624 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,05472648 0,10035969 ! macroautophagy GO:0016236 17 10 0,000 0,05472648 0,10028325 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,05472648 0,10020693 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,05472648 0,10013073 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,05472648 0,10005464 ! copper ion homeostasis GO:0055070 13 10 0,000 0,05472648 0,09997867 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,05472648 0,09990281 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,05472648 0,09982707 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,05472648 0,09975145 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,05472648 0,09967593 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,05472648 0,09960054 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,05472648 0,09952525 ! blastoderm segmentation GO:0007350 18 10 0,000 0,05472648 0,09945008 ! response to dsRNA GO:0043331 20 10 0,000 0,05472648 0,09937503 ! DNA ligation GO:0006266 19 10 0,000 0,05472648 0,09930008 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,05472648 0,09922525 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,05472648 0,09915053 ! melanosome localization GO:0032400 16 10 0,000 0,05472648 0,09907593 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,05472648 0,09900144 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,05472648 0,09892705 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,05472648 0,09885278 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,05472648 0,09877863 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,05472648 0,09870458 ! mRNA cleavage GO:0006379 17 10 0,000 0,05472648 0,09863064 ! protein sumoylation GO:0016925 15 10 0,000 0,05472648 0,09855682 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,05472648 0,0984831 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,05472648 0,0984095 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,05472648 0,098336 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,05472648 0,09826262 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,05472648 0,09818934 ! salivary gland development GO:0007431 27 10 0,000 0,05472648 0,09811618 ! prophase GO:0051324 15 10 0,000 0,05472648 0,09804312 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,05472648 0,09797017 ! apical protein localization GO:0045176 15 10 0,000 0,05472648 0,09789733 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,05472648 0,0978246 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,05472648 0,09775197 ! midbrain development GO:0030901 13 10 0,000 0,05472648 0,09767946 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,05472648 0,09760705 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,05472648 0,09753475 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,05472648 0,09746255 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,05472648 0,09739047 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,05472648 0,09731848 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,05472648 0,09724661 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,05472648 0,09717484 ! detection of calcium ion GO:0005513 23 10 0,000 0,05472648 0,09710318 ! oocyte development GO:0048599 17 10 0,000 0,05472648 0,09703162 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,05472648 0,09696017 ! blastocyst formation GO:0001825 17 10 0,000 0,05472648 0,09688882 ! cerebellar cortex development GO:0021695 15 10 0,000 0,05472648 0,09681758 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,05472648 0,09674644 ! activation of innate immune response GO:0002218 12 10 0,000 0,05472648 0,09667541 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,05472648 0,09660448 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,05472648 0,09653366 ! response to nicotine GO:0035094 20 10 0,000 0,05472648 0,09646294 ! establishment of cell polarity GO:0030010 16 10 0,000 0,05472648 0,09639232 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,05472648 0,09632181 ! amino acid transport GO:0006865 125 68 1,000 0,05604327 0,09856732 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 1,000 0,05604327 0,09849532 ! viral reproduction GO:0016032 134 68 1,000 0,05604327 0,09842343 ! regulation of lipase activity GO:0060191 130 68 1,000 0,05604327 0,09835164 ! protein maturation by peptide bond cleavage GO:0051605 105 68 1,000 0,05604327 0,09827995 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 1,000 0,05604327 0,09820837 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 1,000 0,05750918 0,10070386 ! appendage morphogenesis GO:0035107 135 70 1,000 0,05898839 0,10321896 GO:0035108|limb morphogenesis, ! respiratory burst GO:0045730 17 11 0,000 0,0600326 0,10496978 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,0600326 0,10489355 ! neuron fate specification GO:0048665 17 11 0,000 0,0600326 0,10481743 ! telencephalon cell migration GO:0022029 20 11 0,000 0,0600326 0,10474142 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,0600326 0,10466552 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,0600326 0,10458973 ! thyroid gland development GO:0030878 26 11 0,000 0,0600326 0,10451405 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,0600326 0,10443848 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,0600326 0,10436302 ! response to pain GO:0048265 24 11 0,000 0,0600326 0,10428767 ! T cell proliferation GO:0042098 26 11 0,000 0,0600326 0,10421243 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,0600326 0,10413729 GO:0010812|negative regulation of cell-substrate adhesion, ! bone resorption GO:0045453 16 11 0,000 0,0600326 0,10406227 ! ventral spinal cord development GO:0021517 21 11 0,000 0,0600326 0,10398735 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,0600326 0,10391254 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,0600326 0,10383783 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,0600326 0,10376324 ! melanocyte differentiation GO:0030318 21 11 0,000 0,0600326 0,10368875 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,0600326 0,10361436 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,0600326 0,10354009 GO:0010833|telomere maintenance via telomere lengthening, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,0600326 0,10346592 GO:0043088|regulation of Cdc42 GTPase activity, ! lipid digestion GO:0044241 18 11 0,000 0,0600326 0,10339186 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,0600326 0,1033179 ! UV protection GO:0009650 19 11 0,000 0,0600326 0,10324405 ! adult heart development GO:0007512 14 11 0,000 0,0600326 0,1031703 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,0600326 0,10309666 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,0600326 0,10302313 ! temperature homeostasis GO:0001659 17 11 0,000 0,0600326 0,1029497 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,0600326 0,10287637 ! negative regulation of ossification GO:0030279 26 11 0,000 0,0600326 0,10280315 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,0600326 0,10273003 ! regulation of organ growth GO:0046620 13 11 0,000 0,0600326 0,10265702 ! pigment granule localization GO:0051875 20 11 0,000 0,0600326 0,10258411 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,0600326 0,1025113 ! vasoconstriction GO:0042310 18 11 0,000 0,0600326 0,1024386 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,0600326 0,102366 ! embryonic axis specification GO:0000578 18 11 0,000 0,0600326 0,1022935 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,0600326 0,10222111 ! snRNA metabolic process GO:0016073 24 11 0,000 0,0600326 0,10214881 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,0600326 0,10207662 ! DNA methylation GO:0006306 19 11 0,000 0,0600326 0,10200454 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,0600326 0,10193255 ! zymogen activation GO:0031638 15 11 0,000 0,0600326 0,10186067 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,0600326 0,10178888 ! neuroblast proliferation GO:0007405 24 11 0,000 0,0600326 0,1017172 ! nucleosome positioning GO:0016584 15 11 0,000 0,0600326 0,10164562 ! regulation of isotype switching GO:0045191 22 11 0,000 0,0600326 0,10157414 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,0600326 0,10150276 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,0600326 0,10143148 ! acid secretion GO:0046717 18 11 0,000 0,0600326 0,1013603 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,0600326 0,10128922 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,0600326 0,10121824 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,0600326 0,10114736 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,0600326 0,10107657 ! oocyte differentiation GO:0009994 18 11 0,000 0,0600326 0,10100589 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,0600326 0,10093531 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,0600326 0,10086482 ! cholesterol efflux GO:0033344 19 11 0,000 0,0600326 0,10079443 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,0600326 0,10072415 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,0600326 0,10065395 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,0600326 0,10058386 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,0600326 0,10051386 ! embryonic gut development GO:0048566 15 11 0,000 0,0600326 0,10044397 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,0600326 0,10037417 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,0600326 0,10030446 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,0600326 0,10023485 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,0600326 0,10016534 ! defense response to fungus GO:0050832 13 11 0,000 0,0600326 0,10009593 ! developmental induction GO:0031128 19 11 0,000 0,0600326 0,10002661 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,0600326 0,09995739 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,0600326 0,09988826 ! sequestering of metal ion GO:0051238 14 11 0,000 0,0600326 0,09981923 ! lamellipodium assembly GO:0030032 20 11 0,000 0,0600326 0,09975029 ! nucleus localization GO:0051647 19 11 0,000 0,0600326 0,09968145 ! regulation of synapse organization GO:0050807 17 11 0,000 0,0600326 0,09961271 ! appendage development GO:0048736 136 71 1,000 0,0604807 0,10028709 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 1,000 0,0604807 0,10021802 ! regulation of MAPKKK cascade GO:0043408 142 71 1,000 0,0604807 0,10014905 ! phosphoinositide metabolic process GO:0030384 128 72 1,000 0,06198591 0,10257091 ! carbohydrate transport GO:0008643 110 72 1,000 0,06198591 0,10250042 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 1,000 0,06198591 0,10243002 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 1,000 0,06198591 0,10235972 ! regulation of transcription factor activity GO:0051090 126 74 1,000 0,0650343 0,10731997 GO:0090046|regulation of transcription regulator activity, ! neurotransmitter transport GO:0006836 123 74 1,000 0,0650343 0,10724642 ! leukocyte mediated immunity GO:0002443 128 74 1,000 0,0650343 0,10717296 ! organelle localization GO:0051640 136 74 1,000 0,0650343 0,1070996 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,0653091 0,10747859 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,0653091 0,10740512 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,0653091 0,10733176 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,0653091 0,1072585 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,0653091 0,10718533 ! cartilage condensation GO:0001502 20 12 0,000 0,0653091 0,10711227 ! mating GO:0007618 17 12 0,000 0,0653091 0,1070393 ! protein complex disassembly GO:0043241 27 12 0,000 0,0653091 0,10696644 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,0653091 0,10689367 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,0653091 0,106821 ! hippocampus development GO:0021766 26 12 0,000 0,0653091 0,10674844 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 0,0653091 0,10667597 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,0653091 0,10660359 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,0653091 0,10653132 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,0653091 0,10645914 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,0653091 0,10638707 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,0653091 0,10631509 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,0653091 0,1062432 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,0653091 0,10617142 ! drug transport GO:0015893 16 12 0,000 0,0653091 0,10609973 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,0653091 0,10602814 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,0653091 0,10595664 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,0653091 0,10588524 ! polyamine metabolic process GO:0006595 17 12 0,000 0,0653091 0,10581394 ! mitotic spindle organization GO:0007052 21 12 0,000 0,0653091 0,10574273 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,0653091 0,10567162 ! forebrain cell migration GO:0021885 21 12 0,000 0,0653091 0,1056006 ! asymmetric protein localization GO:0008105 20 12 0,000 0,0653091 0,10552968 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,0653091 0,10545886 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,0653091 0,10538813 ! entry into host cell GO:0030260 32 12 0,000 0,0653091 0,10531749 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,0653091 0,10524695 ! monoamine transport GO:0015844 18 12 0,000 0,0653091 0,1051765 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,0653091 0,10510615 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,0653091 0,10503589 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,0653091 0,10496573 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,0653091 0,10489566 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,0653091 0,10482568 ! protein homotetramerization GO:0051289 21 12 0,000 0,0653091 0,1047558 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,0653091 0,10468601 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,0653091 0,10461631 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,0653091 0,1045467 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,0653091 0,10447719 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,0653091 0,10440777 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,0653091 0,10433844 ! cranial nerve development GO:0021545 20 12 0,000 0,0653091 0,10426921 ! fucose catabolic process GO:0019317 22 12 0,000 0,0653091 0,10420006 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,0653091 0,10413101 ! histone methylation GO:0016571 26 12 0,000 0,0653091 0,10406205 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,0653091 0,10399318 ! autonomic nervous system development GO:0048483 24 12 0,000 0,0653091 0,1039244 ! gland morphogenesis GO:0022612 29 12 0,000 0,0653091 0,10385572 ! T cell homeostasis GO:0043029 25 12 0,000 0,0653091 0,10378712 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,0653091 0,10371861 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,0653091 0,1036502 ! spleen development GO:0048536 22 12 0,000 0,0653091 0,10358187 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,0653091 0,10351363 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,0653091 0,10344549 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,0653091 0,10337743 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,0653091 0,10330947 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,0653091 0,10324159 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,0653091 0,1031738 ! response to cold GO:0009409 17 12 0,000 0,0653091 0,1031061 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,0653091 0,10303849 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,0653091 0,10297097 ! cell-matrix adhesion GO:0007160 163 75 1,000 0,06657709 0,10490143 ! phosphoinositide-mediated signaling GO:0048015 131 75 1,000 0,06657709 0,10483278 ! lymphocyte differentiation GO:0030098 167 75 1,000 0,06657709 0,10476422 ! positive regulation of ligase activity GO:0051351 124 77 1,000 0,06969898 0,10960506 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 0,06969898 0,10953347 ! cGMP metabolic process GO:0046068 18 13 0,000 0,07055616 0,11080818 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,07055616 0,11073589 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,07055616 0,11066371 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,07055616 0,11059161 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,07055616 0,11051961 ! lipid localization GO:0010876 28 13 0,000 0,07055616 0,11044771 GO:0019915|lipid storage, ! organelle fusion GO:0048284 32 13 0,000 0,07055616 0,11037589 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,07055616 0,11030418 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,07055616 0,11023255 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,07055616 0,11016102 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,07055616 0,11008958 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,07055616 0,11001823 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,07055616 0,10994697 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,07055616 0,10987581 ! methionine metabolic process GO:0006555 27 13 0,000 0,07055616 0,10980474 ! plasma membrane organization GO:0007009 24 13 0,000 0,07055616 0,10973376 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,07055616 0,10966287 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,07055616 0,10959208 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,07055616 0,10952137 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,07055616 0,10945076 ! cytokine metabolic process GO:0042107 22 13 0,000 0,07055616 0,10938024 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,07055616 0,1093098 ! exocrine system development GO:0035272 32 13 0,000 0,07055616 0,10923946 ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,07055616 0,10916921 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,07055616 0,10909905 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,07055616 0,10902898 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,07055616 0,108959 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,07055616 0,10888911 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,07055616 0,10881931 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,07055616 0,1087496 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,07055616 0,10867998 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,07055616 0,10861045 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,07055616 0,108541 ! ribosome assembly GO:0042255 17 13 0,000 0,07055616 0,10847165 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,07055616 0,10840238 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,07055616 0,1083332 ! chromatin silencing GO:0006342 26 13 0,000 0,07055616 0,10826411 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,07055616 0,10819511 ! regulation of epidermis development GO:0045682 19 13 0,000 0,07055616 0,10812619 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,07055616 0,10805737 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,07055616 0,10798863 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,07055616 0,10791998 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,07055616 0,10785141 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,07055616 0,10778294 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,07055616 0,10771455 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,07055616 0,10764624 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,07055616 0,10757803 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,07055616 0,1075099 ! insulin secretion GO:0030073 23 13 0,000 0,07055616 0,10744185 ! actin filament polymerization GO:0030041 24 13 0,000 0,07055616 0,10737389 ! acrosome reaction GO:0007340 18 13 0,000 0,07055616 0,10730602 ! blood coagulation GO:0007596 146 78 1,000 0,0712777 0,10833489 GO:0050817|coagulation, ! activation of protein kinase activity GO:0032147 147 79 1,000 0,07286803 0,11068212 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 1,000 0,07286803 0,11061228 ! positive regulation of phosphorylation GO:0042327 129 79 1,000 0,07286803 0,11054254 ! protein import into nucleus GO:0006606 158 80 1,000 0,07446979 0,11290127 ! rRNA transcription GO:0009303 25 14 0,000 0,07577394 0,11480611 ! lactation GO:0007595 26 14 0,000 0,07577394 0,11473386 ! reproductive cellular process GO:0048610 20 14 0,000 0,07577394 0,1146617 ! tRNA modification GO:0006400 20 14 0,000 0,07577394 0,11458963 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,07577394 0,11451765 ! regulation of S phase GO:0033261 23 14 0,000 0,07577394 0,11444576 ! water transport GO:0006833 21 14 0,000 0,07577394 0,11437397 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,07577394 0,11430226 ! non-recombinational repair GO:0000726 25 14 0,000 0,07577394 0,11423064 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,07577394 0,11415911 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,07577394 0,11408767 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,07577394 0,11401632 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,07577394 0,11394506 ! RNA polyadenylation GO:0043631 30 14 0,000 0,07577394 0,11387389 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,07577394 0,11380281 ! palate development GO:0060021 31 14 0,000 0,07577394 0,11373182 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,07577394 0,11366091 ! regulated secretory pathway GO:0045055 23 14 0,000 0,07577394 0,11359009 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,07577394 0,11351937 ! arginine metabolic process GO:0006525 17 14 0,000 0,07577394 0,11344872 ! regulation of heart rate GO:0002027 24 14 0,000 0,07577394 0,11337817 ! organic alcohol transport GO:0015850 29 14 0,000 0,07577394 0,11330771 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,07577394 0,11323733 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,07577394 0,11316704 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,07577394 0,11309684 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,07577394 0,11302672 ! neutral amino acid transport GO:0015804 26 14 0,000 0,07577394 0,11295669 ! stem cell development GO:0048864 43 14 0,000 0,07577394 0,11288675 GO:0019827|stem cell maintenance, ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,07577394 0,11281689 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,07577394 0,11274712 ! cerebellum development GO:0021549 21 14 0,000 0,07577394 0,11267744 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,07577394 0,11260784 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,07577394 0,11253833 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,07577394 0,11246891 ! cofactor transport GO:0051181 26 14 0,000 0,07577394 0,11239957 ! NADP metabolic process GO:0006739 24 14 0,000 0,07577394 0,11233031 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,07577394 0,11226115 ! intestinal absorption GO:0050892 25 14 0,000 0,07577394 0,11219206 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,07577394 0,11212306 ! oxygen transport GO:0015671 21 14 0,000 0,07577394 0,11205415 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,07577394 0,11198532 ! male genitalia development GO:0030539 24 14 0,000 0,07577394 0,11191658 ! regulation of axon extension GO:0030516 37 14 0,000 0,07577394 0,11184791 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,07577394 0,11177934 ! T cell activation GO:0042110 168 81 1,000 0,07608281 0,11216621 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 1,000 0,07608281 0,11209752 GO:0045937|positive regulation of phosphate metabolic process, ! digestion GO:0007586 112 81 1,000 0,07608281 0,11202892 ! nuclear import GO:0051170 161 81 1,000 0,07608281 0,1119604 ! regulation of neuron differentiation GO:0045664 167 81 1,000 0,07608281 0,11189196 ! response to drug GO:0042493 143 82 1,000 0,07770692 0,11421066 ! response to nutrient GO:0007584 125 82 1,000 0,07770692 0,11414093 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,0809626 0,11885053 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,0809626 0,11877806 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! superoxide anion generation GO:0042554 20 15 0,000 0,0809626 0,11870568 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,0809626 0,11863338 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,0809626 0,11856118 ! copper ion transport GO:0006825 20 15 0,000 0,0809626 0,11848906 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,0809626 0,11841703 ! sulfate transport GO:0008272 23 15 0,000 0,0809626 0,11834509 ! response to cAMP GO:0051591 22 15 0,000 0,0809626 0,11827323 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,0809626 0,11820147 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,0809626 0,11812978 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,0809626 0,11805819 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,0809626 0,11798668 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,0809626 0,11791526 ! response to hexose stimulus GO:0009746 22 15 0,000 0,0809626 0,11784393 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,0809626 0,11777268 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,0809626 0,11770152 ! pituitary gland development GO:0021983 29 15 0,000 0,0809626 0,11763044 ! vesicle coating GO:0006901 33 15 0,000 0,0809626 0,11755945 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,0809626 0,11748855 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,0809626 0,11741773 ! regulation of exocytosis GO:0017157 22 15 0,000 0,0809626 0,117347 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,0809626 0,11727635 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,0809626 0,11720579 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,0809626 0,11713531 ! regulation of vasodilation GO:0042312 26 15 0,000 0,0809626 0,11706491 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,0809626 0,1169946 ! histone deacetylation GO:0016575 20 15 0,000 0,0809626 0,11692438 ! mRNA splice site selection GO:0006376 38 15 0,000 0,0809626 0,11685424 ! tissue regeneration GO:0042246 26 15 0,000 0,0809626 0,11678418 ! water homeostasis GO:0030104 27 15 0,000 0,0809626 0,11671421 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,0809626 0,11664432 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,0809626 0,11657452 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,0809626 0,11650479 ! dopamine metabolic process GO:0042417 35 15 0,000 0,0809626 0,11643516 ! heme biosynthetic process GO:0006783 29 15 0,000 0,0809626 0,1163656 ! cell killing GO:0001906 29 15 0,000 0,0809626 0,11629613 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,0809626 0,11622674 ! detection of bacterium GO:0016045 18 15 0,000 0,0809626 0,11615743 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,0809626 0,11608821 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,0809626 0,11601907 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,0809626 0,11595001 ! peptide hormone processing GO:0016486 23 15 0,000 0,0809626 0,11588103 ! hemostasis GO:0007599 158 84 1,000 0,08098768 0,11584802 ! regulation of ligase activity GO:0051340 142 84 1,000 0,08098768 0,11577918 ! nucleosome assembly GO:0006334 122 85 1,000 0,082644 0,11807688 ! one-carbon metabolic process GO:0006730 154 85 1,000 0,082644 0,1180068 ! positive regulation of cell activation GO:0050867 145 85 1,000 0,082644 0,11793681 GO:0002696|positive regulation of leukocyte activation, ! chromatin assembly GO:0031497 124 86 1,000 0,08431071 0,12024397 ! amine transport GO:0015837 155 86 1,000 0,08431071 0,12017274 ! protein localization in nucleus GO:0034504 176 87 1,000 0,08598766 0,12249042 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,0861223 0,12260962 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,0861223 0,12253711 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,0861223 0,12246469 ! bone remodeling GO:0046849 27 16 0,000 0,0861223 0,12239235 ! filopodium assembly GO:0046847 32 16 0,000 0,0861223 0,1223201 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,0861223 0,12224794 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,0861223 0,12217586 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,0861223 0,12210386 ! startle response GO:0001964 28 16 0,000 0,0861223 0,12203195 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,0861223 0,12196013 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,0861223 0,12188839 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,0861223 0,12181673 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,0861223 0,12174516 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,0861223 0,12167367 ! protein polyubiquitination GO:0000209 34 16 0,000 0,0861223 0,12160226 ! glutamate metabolic process GO:0006536 22 16 0,000 0,0861223 0,12153094 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,0861223 0,1214597 ! response to osmotic stress GO:0006970 25 16 0,000 0,0861223 0,12138855 ! lysosomal transport GO:0007041 26 16 0,000 0,0861223 0,12131748 ! fructose metabolic process GO:0006000 25 16 0,000 0,0861223 0,12124649 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,0861223 0,12117559 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,0861223 0,12110477 ! intermediate filament-based process GO:0045103 32 16 0,000 0,0861223 0,12103403 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,0861223 0,12096337 ! negative regulation of immune response GO:0050777 35 16 0,000 0,0861223 0,1208928 ! axon cargo transport GO:0008088 43 16 0,000 0,0861223 0,12082231 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,0861223 0,1207519 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,0861223 0,12068157 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 0,0861223 0,12061132 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,0861223 0,12054116 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,0861223 0,12047108 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,0861223 0,12040108 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,0861223 0,12033116 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,0861223 0,12026132 GO:0046466|membrane lipid catabolic process, ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,0861223 0,12019156 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,0861223 0,12012189 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,0861223 0,12005229 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,0861223 0,11998278 ! defense response to virus GO:0051607 37 16 0,000 0,0861223 0,11991334 ! sex differentiation GO:0007548 145 90 1,000 0,09107824 0,12674045 ! protein-DNA complex assembly GO:0065004 130 90 1,000 0,09107824 0,12666719 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,0912532 0,12683721 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,0912532 0,12676398 ! metencephalon development GO:0022037 30 17 0,000 0,0912532 0,12669083 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,0912532 0,12661777 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,0912532 0,12654479 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,0912532 0,12647189 ! signal complex assembly GO:0007172 41 17 0,000 0,0912532 0,12639908 ! endothelial cell migration GO:0043542 28 17 0,000 0,0912532 0,12632636 ! inositol metabolic process GO:0006020 28 17 0,000 0,0912532 0,12625371 ! gene silencing by RNA GO:0031047 36 17 0,000 0,0912532 0,12618115 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,0912532 0,12610868 ! glial cell development GO:0021782 27 17 0,000 0,0912532 0,12603629 ! limbic system development GO:0021761 36 17 0,000 0,0912532 0,12596398 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,0912532 0,12589175 ! adult walking behavior GO:0007628 33 17 0,000 0,0912532 0,1258196 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,0912532 0,12574754 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,0912532 0,12567556 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,0912532 0,12560367 ! myoblast differentiation GO:0045445 45 17 0,000 0,0912532 0,12553185 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,0912532 0,12546012 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,0912532 0,12538847 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,0912532 0,1253169 ! glycine metabolic process GO:0006544 28 17 0,000 0,0912532 0,12524541 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,0912532 0,12517401 ! NAD metabolic process GO:0019674 29 17 0,000 0,0912532 0,12510268 ! membrane budding GO:0006900 37 17 0,000 0,0912532 0,12503144 ! DNA integration GO:0015074 29 17 0,000 0,0912532 0,12496028 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,0912532 0,1248892 ! regulation of protein binding GO:0043393 33 17 0,000 0,0912532 0,1248182 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,0912532 0,12474728 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,0912532 0,12467644 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,0912532 0,12460568 ! genitalia development GO:0048806 30 17 0,000 0,0912532 0,124535 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,0912532 0,1244644 GO:0002712|regulation of B cell mediated immunity, ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,0912532 0,12439389 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,0912532 0,12432345 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,0912532 0,12425309 ! steroid catabolic process GO:0006706 31 17 0,000 0,0912532 0,12418281 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,0912532 0,12411261 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,0912532 0,12404249 ! gas transport GO:0015669 25 17 0,000 0,0912532 0,12397245 ! organic cation transport GO:0015695 31 17 0,000 0,0912532 0,12390249 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,0912532 0,12383261 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,0912532 0,1237628 ! microspike assembly GO:0030035 36 17 0,000 0,0912532 0,12369308 ! nucleosome organization GO:0034728 138 92 1,000 0,09452011 0,12804921 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 1,000 0,09625502 0,13032615 GO:0010498|proteasomal protein catabolic process, ! regulation of membrane potential GO:0042391 164 93 1,000 0,09625502 0,13025285 ! negative regulation of multicellular organismal process GO:0051241 166 93 1,000 0,09625502 0,13017964 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,09635547 0,13024228 ! neuron maturation GO:0042551 42 18 0,000 0,09635547 0,13016915 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,09635547 0,13009611 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,09635547 0,13002314 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,09635547 0,12995026 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,09635547 0,12987746 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,09635547 0,12980474 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,09635547 0,1297321 ! patterning of blood vessels GO:0001569 39 18 0,000 0,09635547 0,12965954 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,09635547 0,12958707 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,09635547 0,12951467 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,09635547 0,12944236 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,09635547 0,12937012 ! glutamine metabolic process GO:0006541 29 18 0,000 0,09635547 0,12929797 ! response to fungus GO:0009620 21 18 0,000 0,09635547 0,1292259 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,09635547 0,12915391 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,09635547 0,12908199 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,09635547 0,12901016 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,09635547 0,12893841 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,09635547 0,12886674 ! vitamin transport GO:0051180 27 18 0,000 0,09635547 0,12879515 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,09635547 0,12872363 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,09635547 0,1286522 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,09635547 0,12858084 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,09635547 0,12850957 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,09635547 0,12843837 ! nerve development GO:0021675 28 18 0,000 0,09635547 0,12836725 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,09635547 0,12829622 ! transcription initiation GO:0006352 153 94 1,000 0,09799903 0,13041242 ! regulation of T cell activation GO:0050863 158 94 1,000 0,09799903 0,13034033 ! forebrain development GO:0030900 188 95 1,000 0,09975198 0,13259849 ! regulation of Rho protein signal transduction GO:0035023 213 95 1,000 0,09975198 0,13252527 ! protein secretion GO:0009306 39 19 0,000 0,10142926 0,13467925 ! negative regulation of defense response GO:0031348 25 19 0,000 0,10142926 0,13460496 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,10142926 0,13453076 ! skin development GO:0043588 36 19 0,000 0,10142926 0,13445664 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,10142926 0,1343826 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,10142926 0,13430864 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,10142926 0,13423476 ! bile acid metabolic process GO:0008206 29 19 0,000 0,10142926 0,13416096 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,10142926 0,13408725 ! cerebral cortex development GO:0021987 36 19 0,000 0,10142926 0,13401362 ! pigmentation during development GO:0048066 41 19 0,000 0,10142926 0,13394006 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,10142926 0,13386659 GO:0030968|endoplasmic reticulum unfolded protein response, ! heme metabolic process GO:0042168 36 19 0,000 0,10142926 0,1337932 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,10142926 0,13371989 ! protein export from nucleus GO:0006611 36 19 0,000 0,10142926 0,13364666 ! heart process GO:0003015 30 19 0,000 0,10142926 0,13357351 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,10142926 0,13350043 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,10142926 0,13342744 ! visual learning GO:0008542 36 19 0,000 0,10142926 0,13335453 ! cellular pigmentation GO:0033059 36 19 0,000 0,10142926 0,1332817 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,10142926 0,13320895 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,10142926 0,13313628 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,10142926 0,13306368 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,10142926 0,13299117 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,10142926 0,13291873 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,10142926 0,13284638 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,10142926 0,1327741 ! cilium assembly GO:0042384 37 19 0,000 0,10142926 0,1327019 ! peptide hormone secretion GO:0030072 31 19 0,000 0,10142926 0,13262978 ! leukocyte differentiation GO:0002521 202 96 1,000 0,10151373 0,13266814 ! detection of stimulus GO:0051606 151 96 1,000 0,10151373 0,13259611 ! protein ubiquitination GO:0016567 217 97 1,000 0,10328412 0,13483538 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,10647472 0,13892526 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,10647472 0,13884997 ! positive regulation of ossification GO:0045778 47 20 0,000 0,10647472 0,13877475 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,10647472 0,13869961 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,10647472 0,13862456 ! cAMP metabolic process GO:0046058 36 20 0,000 0,10647472 0,13854959 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,10647472 0,1384747 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,10647472 0,13839988 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,10647472 0,13832515 ! retinoid metabolic process GO:0001523 32 20 0,000 0,10647472 0,13825051 GO:0016101|diterpenoid metabolic process, ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,10647472 0,13817594 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,10647472 0,13810145 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,10647472 0,13802704 GO:0032392|DNA geometric change, ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,10647472 0,13795271 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,10647472 0,13787846 ! body fluid secretion GO:0007589 31 20 0,000 0,10647472 0,1378043 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,10647472 0,13773021 ! peptide secretion GO:0002790 35 20 0,000 0,10647472 0,1376562 ! stem cell differentiation GO:0048863 53 20 0,000 0,10647472 0,13758227 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,10647472 0,13750842 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,10647472 0,13743465 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,10647472 0,13736096 ! sensory perception of pain GO:0019233 30 20 0,000 0,10647472 0,13728735 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,10647472 0,13721381 ! diencephalon development GO:0021536 34 20 0,000 0,10647472 0,13714036 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,10647472 0,13706698 GO:0006626|protein targeting to mitochondrion, ! detection of chemical stimulus GO:0009593 37 20 0,000 0,10647472 0,13699368 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,10647472 0,13692046 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,10647472 0,13684732 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,10647472 0,13677426 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,10647472 0,13670127 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,10647472 0,13662837 ! regulation of glucose import GO:0046324 29 20 0,000 0,10647472 0,13655554 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,10647472 0,13648278 ! actin filament-based movement GO:0030048 43 20 0,000 0,10647472 0,13641011 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,10647472 0,13633751 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,10647472 0,13626499 ! negative regulation of translation GO:0017148 29 20 0,000 0,10647472 0,13619255 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,10647472 0,13612018 ! regulation of cell killing GO:0031341 42 21 0,000 0,11149203 0,14245875 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,11149203 0,14238313 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,11149203 0,1423076 ! hormone secretion GO:0046879 38 21 0,000 0,11149203 0,14223214 ! glycerol metabolic process GO:0006071 34 21 0,000 0,11149203 0,14215677 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,11149203 0,14208147 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,11149203 0,14200626 ! ovarian follicle development GO:0001541 35 21 0,000 0,11149203 0,14193112 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,11149203 0,14185606 ! smooth muscle contraction GO:0006939 46 21 0,000 0,11149203 0,14178109 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,11149203 0,14170619 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,11149203 0,14163137 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,11149203 0,14155663 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,11149203 0,14148197 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,11149203 0,14140739 ! vasodilation GO:0042311 39 21 0,000 0,11149203 0,14133289 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,11149203 0,14125846 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,11149203 0,14118411 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,11149203 0,14110985 ! oogenesis GO:0048477 36 21 0,000 0,11149203 0,14103566 ! DNA modification GO:0006304 34 21 0,000 0,11149203 0,14096154 ! collagen fibril organization GO:0030199 59 21 0,000 0,11149203 0,14088751 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,11149203 0,14081355 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,11149203 0,14073967 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,11149203 0,14066587 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,11149203 0,14059215 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,11149203 0,1405185 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,11149203 0,14044493 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,11149203 0,14037144 ! collagen catabolic process GO:0030574 28 21 0,000 0,11149203 0,14029802 ! sperm-egg recognition GO:0035036 21 21 0,000 0,11149203 0,14022468 ! gut development GO:0048565 39 21 0,000 0,11149203 0,14015142 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,11648132 0,14634677 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,11648132 0,14627039 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,11648132 0,14619409 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,11648132 0,14611786 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,11648132 0,14604172 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,11648132 0,14596566 ! regeneration GO:0031099 41 22 0,000 0,11648132 0,14588967 ! keratinization GO:0031424 28 22 0,000 0,11648132 0,14581377 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,11648132 0,14573794 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,11648132 0,1456622 ! sensory perception of taste GO:0050909 28 22 0,000 0,11648132 0,14558653 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,11648132 0,14551094 ! vacuolar transport GO:0007034 36 22 0,000 0,11648132 0,14543542 ! lysosome organization GO:0007040 41 22 0,000 0,11648132 0,14535999 ! central nervous system neuron development GO:0021954 46 22 0,000 0,11648132 0,14528464 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,11648132 0,14520936 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,11648132 0,14513416 ! fucose metabolic process GO:0006004 39 22 0,000 0,11648132 0,14505904 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,11648132 0,144984 ! ureteric bud development GO:0001657 43 22 0,000 0,11648132 0,14490903 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,11648132 0,14483414 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,11648132 0,14475933 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,11648132 0,1446846 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,11648132 0,14460994 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,11648132 0,14453536 ! sarcomere organization GO:0045214 30 22 0,000 0,11648132 0,14446086 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,11648132 0,14438643 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,11648132 0,14431208 ! protein stabilization GO:0050821 39 22 0,000 0,11648132 0,14423781 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,12144277 0,15030417 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,12144277 0,15022689 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,12144277 0,15014969 ! gluconeogenesis GO:0006094 33 23 0,000 0,12144277 0,15007257 ! viral genome replication GO:0019079 41 23 0,000 0,12144277 0,14999553 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,12144277 0,14991857 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,12144277 0,14984169 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,12144277 0,14976489 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,12144277 0,14968817 GO:0006044|N-acetylglucosamine metabolic process, ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,12144277 0,14961152 ! visual behavior GO:0007632 42 23 0,000 0,12144277 0,14953495 ! regulation of DNA recombination GO:0000018 48 23 0,000 0,12144277 0,14945846 ! response to ethanol GO:0045471 46 23 0,000 0,12144277 0,14938205 ! peroxisome organization GO:0007031 37 23 0,000 0,12144277 0,14930572 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,12144277 0,14922947 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,12144277 0,14915329 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,12144277 0,14907719 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,12144277 0,14900117 GO:0051693|actin filament capping, ! regulation of viral reproduction GO:0050792 38 23 0,000 0,12144277 0,14892523 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,12144277 0,14884936 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,12144277 0,14877357 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,12144277 0,14869786 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,12144277 0,14862223 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,12144277 0,14854667 ! fatty acid transport GO:0015908 44 23 0,000 0,12144277 0,14847119 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,12144277 0,14839578 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,12144277 0,14832046 ! hormone transport GO:0009914 40 23 0,000 0,12144277 0,1482452 ! cell-cell recognition GO:0009988 25 23 0,000 0,12144277 0,14817003 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,12144277 0,14809493 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,12144277 0,14801991 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,12144277 0,14794496 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,12144277 0,14787009 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,12144277 0,14779529 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,12637651 0,15372189 GO:0016444|somatic cell DNA recombination, ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,12637651 0,15364421 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,12637651 0,15356661 ! vesicle docking GO:0048278 47 24 0,000 0,12637651 0,15348909 ! spinal cord development GO:0021510 47 24 0,000 0,12637651 0,15341165 ! vacuole organization GO:0007033 43 24 0,000 0,12637651 0,15333429 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,12637651 0,153257 ! digestive system process GO:0022600 39 24 0,000 0,12637651 0,15317979 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,12637651 0,15310266 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,12637651 0,15302561 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,12637651 0,15294864 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,12637651 0,15287174 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,12637651 0,15279492 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,12637651 0,15271818 ! membrane depolarization GO:0051899 39 24 0,000 0,12637651 0,15264151 ! pallium development GO:0021543 49 24 0,000 0,12637651 0,15256492 ! pentose metabolic process GO:0019321 35 24 0,000 0,12637651 0,15248841 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,12637651 0,15241198 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,12637651 0,15233562 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,12637651 0,15225934 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,12637651 0,15218313 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,12637651 0,152107 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,12637651 0,15203095 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,12637651 0,15195497 ! regulation of amine transport GO:0051952 40 24 0,000 0,12637651 0,15187907 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,13128272 0,15769656 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,13128272 0,15761787 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,13128272 0,15753926 ! phototransduction GO:0007602 33 25 0,000 0,13128272 0,15746073 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,13128272 0,15738227 GO:0006479|protein amino acid methylation, ! sperm motility GO:0030317 31 25 0,000 0,13128272 0,15730389 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,13128272 0,15722559 ! receptor metabolic process GO:0043112 46 25 0,000 0,13128272 0,15714737 ! chromosome condensation GO:0030261 45 25 0,000 0,13128272 0,15706923 ! osteoblast differentiation GO:0001649 60 25 0,000 0,13128272 0,15699116 ! coenzyme catabolic process GO:0009109 39 25 0,000 0,13128272 0,15691317 ! regulation of insulin secretion GO:0050796 37 25 0,000 0,13128272 0,15683526 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,13128272 0,15675743 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,13128272 0,15667967 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,13128272 0,15660199 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,13128272 0,15652439 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! immunoglobulin production GO:0002377 55 25 0,000 0,13128272 0,15644686 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,13128272 0,15636941 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,13128272 0,15629204 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,13128272 0,15621475 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,13128272 0,15613753 ! telomere organization GO:0032200 43 25 0,000 0,13128272 0,15606038 GO:0000723|telomere maintenance, ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,13616153 0,16178007 ! embryonic pattern specification GO:0009880 44 26 0,000 0,13616153 0,16170022 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,13616153 0,16162044 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,13616153 0,16154075 ! initiation of viral infection GO:0019059 57 26 0,000 0,13616153 0,16146113 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,13616153 0,1613816 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,13616153 0,16130214 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,13616153 0,16122276 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,13616153 0,16114345 ! molting cycle process GO:0022404 50 26 0,000 0,13616153 0,16106423 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,13616153 0,16098508 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,13616153 0,16090601 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,13616153 0,16082702 GO:0051297|centrosome organization, ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,13616153 0,16074811 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,13616153 0,16066927 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,13616153 0,16059051 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,13616153 0,16051183 ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,13616153 0,16043322 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,13616153 0,16035469 ! blastocyst development GO:0001824 49 26 0,000 0,13616153 0,16027624 ! leukocyte proliferation GO:0070661 52 26 0,000 0,13616153 0,16019787 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,13616153 0,16011957 ! neuron fate commitment GO:0048663 48 27 0,000 0,1410131 0,16574378 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,1410131 0,16566285 ! iron ion transport GO:0006826 59 27 0,000 0,1410131 0,165582 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,1410131 0,16550123 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,1410131 0,16542054 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,1410131 0,16533992 ! fat cell differentiation GO:0045444 50 27 0,000 0,1410131 0,16525939 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,1410131 0,16517893 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,1410131 0,16509855 ! autophagy GO:0006914 41 27 0,000 0,1410131 0,16501825 ! male gonad development GO:0008584 44 27 0,000 0,1410131 0,16493803 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,1410131 0,16485788 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,1410131 0,16477782 ! glutathione metabolic process GO:0006749 39 27 0,000 0,1410131 0,16469783 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,1410131 0,16461792 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,1410131 0,16453808 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,1410131 0,16445833 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,14583759 0,17000254 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,14583759 0,16992021 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,14583759 0,16983797 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,14583759 0,1697558 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,14583759 0,16967371 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,14583759 0,16959171 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,14583759 0,16950978 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,14583759 0,16942793 ! synaptogenesis GO:0007416 42 28 0,000 0,14583759 0,16934616 ! lipid oxidation GO:0034440 43 28 0,000 0,14583759 0,16926447 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,14583759 0,16918285 ! translational initiation GO:0006413 65 29 0,000 0,15063514 0,17466416 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,15063514 0,17458003 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,15063514 0,17449598 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,15063514 0,174412 ! catechol metabolic process GO:0009712 54 29 0,000 0,15063514 0,17432811 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,15063514 0,1742443 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,15063514 0,17416057 ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,15063514 0,17407692 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,15063514 0,17399335 ! cell fate determination GO:0001709 60 29 0,000 0,15063514 0,17390986 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,15063514 0,17382645 ! detection of light stimulus GO:0009583 38 29 0,000 0,15063514 0,17374312 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,15063514 0,17365987 ! regulation of coagulation GO:0050818 46 29 0,000 0,15063514 0,1735767 ! phenol metabolic process GO:0018958 55 30 0,000 0,1554059 0,17898832 ! zinc ion transport GO:0006829 45 30 0,000 0,1554059 0,17890268 ! membrane docking GO:0022406 61 30 0,000 0,1554059 0,17881712 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,1554059 0,17873164 ! regulation of innate immune response GO:0045088 51 30 0,000 0,1554059 0,17864625 ! myofibril assembly GO:0030239 47 30 0,000 0,1554059 0,17856093 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,1554059 0,1784757 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,1554059 0,17839055 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,1554059 0,17830548 ! phospholipid transport GO:0015914 51 30 0,000 0,1554059 0,17822049 ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,1554059 0,17813559 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,1554059 0,17805076 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,1554059 0,17796601 ! eye morphogenesis GO:0048592 60 30 0,000 0,1554059 0,17788135 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,16015002 0,18322442 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,16015002 0,18313733 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,16015002 0,18305033 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,16015002 0,18296341 GO:0009799|determination of symmetry, ! inner ear morphogenesis GO:0042472 47 31 0,000 0,16015002 0,18287658 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,16015002 0,18278982 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,16015002 0,18270315 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,16015002 0,18261656 ! ovulation cycle process GO:0022602 49 31 0,000 0,16015002 0,18253006 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,16015002 0,18244363 ! peptide transport GO:0015833 55 31 0,000 0,16015002 0,18235729 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,16015002 0,18227103 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,16015002 0,18218485 ! mesoderm formation GO:0001707 69 31 0,000 0,16015002 0,18209875 ! natural killer cell activation GO:0030101 45 31 0,000 0,16015002 0,18201273 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,16015002 0,18192679 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,16015002 0,18184094 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,16015002 0,18175517 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,16015002 0,18166947 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,16015002 0,18158386 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,16486765 0,18684483 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,16486765 0,18675686 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,16486765 0,18666897 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,16486765 0,18658117 ! cholesterol transport GO:0030301 56 32 0,000 0,16486765 0,18649345 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,16486765 0,18640581 ! spliceosome assembly GO:0000245 67 32 0,000 0,16486765 0,18631826 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,16486765 0,18623078 ! metanephros development GO:0001656 74 32 0,000 0,16486765 0,18614339 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,16486765 0,18605608 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,16486765 0,18596886 ! muscle cell development GO:0055001 49 32 0,000 0,16486765 0,18588171 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,16486765 0,18579465 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,16486765 0,18570766 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,16486765 0,18562076 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,16486765 0,18553394 ! ovulation cycle GO:0042698 51 32 0,000 0,16486765 0,1854472 ! BMP signaling pathway GO:0030509 64 32 0,000 0,16486765 0,18536055 ! hindbrain development GO:0030902 61 32 0,000 0,16486765 0,18527397 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,16486765 0,18518747 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,16486765 0,18510106 ! gene silencing GO:0016458 65 32 0,000 0,16486765 0,18501473 ! post-embryonic development GO:0009791 69 33 0,000 0,16955894 0,19019059 ! protein targeting to membrane GO:0006612 68 33 0,000 0,16955894 0,19010196 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,16955894 0,19001342 ! ceramide metabolic process GO:0006672 64 33 0,000 0,16955894 0,18992496 ! formation of primary germ layer GO:0001704 72 33 0,000 0,16955894 0,18983658 ! cell fate specification GO:0001708 52 33 0,000 0,16955894 0,18974828 ! sterol transport GO:0015918 57 33 0,000 0,16955894 0,18966007 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,16955894 0,18957194 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,16955894 0,18948389 ! adult locomotory behavior GO:0008344 59 33 0,000 0,16955894 0,18939592 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,16955894 0,18930803 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,17422403 0,19442626 ! glial cell differentiation GO:0010001 63 34 0,000 0,17422403 0,19433612 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,17422403 0,19424607 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,17422403 0,1941561 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,17422403 0,19406621 ! mismatch repair GO:0006298 46 34 0,000 0,17422403 0,19397641 ! spermatid development GO:0007286 63 34 0,000 0,17422403 0,19388668 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,17422403 0,19379705 ! negative regulation of secretion GO:0051048 63 35 0,000 0,17886306 0,19886531 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,17886306 0,19877346 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,17886306 0,19868169 ! odontogenesis GO:0042476 66 35 0,000 0,17886306 0,19859 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,17886306 0,1984984 ! female gonad development GO:0008585 58 35 0,000 0,17886306 0,19840689 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,17886306 0,19831545 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,17886306 0,19822411 ! cytokine production GO:0001816 59 35 0,000 0,17886306 0,19813284 ! vesicle localization GO:0051648 64 35 0,000 0,17886306 0,19804166 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,18347619 0,20305599 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,18347619 0,20296263 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,18347619 0,20286936 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,18347619 0,20277617 ! positive regulation of cell development GO:0010720 80 36 0,000 0,18347619 0,20268307 ! regulation of proteolysis GO:0030162 72 36 0,000 0,18347619 0,20259005 ! aerobic respiration GO:0009060 55 36 0,000 0,18347619 0,20249712 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,18347619 0,20240427 ! RNA export from nucleus GO:0006405 56 37 0,000 0,18806356 0,20736981 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,18806356 0,20727482 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,18806356 0,20717991 ! actomyosin structure organization GO:0031032 62 37 0,000 0,18806356 0,20708509 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,18806356 0,20699036 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,18806356 0,20689571 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,18806356 0,20680115 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,18806356 0,20670668 ! pigment metabolic process GO:0042440 80 37 0,000 0,18806356 0,20661229 ! spermatid differentiation GO:0048515 66 37 0,000 0,18806356 0,20651799 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,1926253 0,21143087 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,1926253 0,21133446 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,1926253 0,21123814 ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,1926253 0,2111419 GO:0046660|female sex differentiation, ! lipid homeostasis GO:0055088 67 38 0,000 0,1926253 0,21104575 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,1926253 0,21094969 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,1926253 0,21085372 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,1926253 0,21075783 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,1926253 0,21066204 ! mRNA catabolic process GO:0006402 71 39 0,000 0,19716157 0,21552509 ! organic ether metabolic process GO:0018904 55 39 0,000 0,19716157 0,21542722 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,19716157 0,21532943 ! ion transmembrane transport GO:0034220 66 39 0,000 0,19716157 0,21523173 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,19716157 0,21513412 ! RNA modification GO:0009451 57 39 0,000 0,19716157 0,2150366 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,2016725 0,21985683 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,2016725 0,21975726 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,2016725 0,21965778 ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,2016725 0,21955838 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,20615823 0,22434043 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,20615823 0,22423901 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,20615823 0,22413768 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,20615823 0,22403645 ! female gamete generation GO:0007292 61 41 0,000 0,20615823 0,2239353 ! polyol metabolic process GO:0019751 66 41 0,000 0,20615823 0,22383425 ! response to reactive oxygen species GO:0000302 67 42 0,000 0,2106189 0,22857424 ! regulation of tube size GO:0035150 71 42 0,000 0,2106189 0,22847118 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,2106189 0,22836822 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,2106189 0,22826535 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,2106189 0,22816258 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,2106189 0,22805989 ! regulation of protein secretion GO:0050708 71 42 0,000 0,2106189 0,2279573 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,21505466 0,23265356 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,21505466 0,23254899 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,21505466 0,23244452 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,21505466 0,23234015 ! striated muscle contraction GO:0006941 77 43 0,000 0,21505466 0,23223587 ! phagocytosis GO:0006909 90 43 0,000 0,21505466 0,23213168 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,21505466 0,23202758 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,21946564 0,23668056 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,21946564 0,23657452 ! male sex differentiation GO:0046661 76 44 0,000 0,21946564 0,23646857 ! biopolymer methylation GO:0043414 84 44 0,000 0,21946564 0,23636272 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,21946564 0,23625697 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,21946564 0,23615131 ! developmental growth GO:0048589 82 44 0,000 0,21946564 0,23604574 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,22385198 0,24065588 ! glycolysis GO:0006096 65 45 0,000 0,22385198 0,24054839 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,22385198 0,24044101 ! leukocyte migration GO:0050900 68 45 0,000 0,22385198 0,24033371 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,22385198 0,24022652 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,22385198 0,24011942 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,22385198 0,24001241 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,22385198 0,2399055 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,22385198 0,23979869 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,22821381 0,24436245 ! positive regulation of defense response GO:0031349 76 47 0,000 0,23255127 0,24889607 ! response to calcium ion GO:0051592 81 47 0,000 0,23255127 0,2487854 ! endosome transport GO:0016197 108 47 0,000 0,23255127 0,24867483 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,23255127 0,24856435 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,23255127 0,24845398 ! methylation GO:0032259 90 47 0,000 0,23255127 0,2483437 ! Notch signaling pathway GO:0007219 96 48 0,000 0,2368645 0,25283762 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,2368645 0,25272549 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,2368645 0,25261347 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,2368645 0,25250155 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,24115363 0,25695998 ! regulation of ion transport GO:0043269 77 49 0,000 0,24115363 0,25684623 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,24115363 0,25673258 ! peptide metabolic process GO:0006518 76 49 0,000 0,24115363 0,25661904 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,24115363 0,25650559 ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,24115363 0,25639224 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,2454188 0,26081167 ! neuromuscular process GO:0050905 99 50 0,000 0,2454188 0,26069653 ! inner ear development GO:0048839 79 50 0,000 0,2454188 0,26058148 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,2454188 0,26046653 ! viral infectious cycle GO:0019058 99 51 0,000 0,24966013 0,2648511 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,24966013 0,26473437 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,24966013 0,26461775 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,24966013 0,26450123 ! excretion GO:0007588 83 51 0,000 0,24966013 0,26438481 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,24966013 0,26426849 ! chromatin remodeling GO:0006338 109 51 0,000 0,24966013 0,26415228 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,24966013 0,26403617 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,24966013 0,26392016 ! vesicle organization GO:0016050 107 51 0,000 0,24966013 0,26380425 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,25387777 0,26814307 ! amino acid activation GO:0043038 92 52 0,000 0,25387777 0,26802541 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 76 53 0,000 0,25807184 0,2723337 ! RNA catabolic process GO:0006401 93 53 0,000 0,25807184 0,27221431 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,25807184 0,27209502 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,25807184 0,27197584 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,25807184 0,27185676 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,25807184 0,27173779 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,26224247 0,27600848 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,26224247 0,27588779 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,26224247 0,27576721 ! chloride transport GO:0006821 90 55 0,000 0,26638979 0,28000605 ! glucose catabolic process GO:0006007 82 55 0,000 0,26638979 0,27988378 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,26638979 0,27976161 ! gastrulation GO:0007369 112 55 0,000 0,26638979 0,27963955 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,26638979 0,2795176 ! RNA elongation GO:0006354 79 55 0,000 0,26638979 0,27939575 ! nuclear export GO:0051168 97 55 0,000 0,26638979 0,27927401 ! regulation of actin filament length GO:0030832 105 56 0,000 0,27051394 0,2834741 ! sensory perception of smell GO:0007608 80 56 0,000 0,27051394 0,28335069 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,27051394 0,28322739 ! proton transport GO:0015992 94 56 0,000 0,27051394 0,2831042 ! hydrogen transport GO:0006818 97 58 0,000 0,27869322 0,29153734 ! regulation of endocytosis GO:0030100 91 58 0,000 0,27869322 0,29141064 ! adult behavior GO:0030534 99 58 0,000 0,27869322 0,29128405 ! positive regulation of secretion GO:0051047 95 59 0,000 0,28274861 0,29539433 ! regulation of cellular component size GO:0032535 109 59 0,000 0,28274861 0,29526612 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,28274861 0,29513802 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,28274861 0,29501004 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,28678133 0,29908794 ! regulation of heart contraction GO:0008016 110 60 0,000 0,28678133 0,29895835 ! camera-type eye development GO:0043010 116 60 0,000 0,28678133 0,29882887 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,28678133 0,29869951 ! kidney development GO:0001822 122 60 0,000 0,28678133 0,29857026 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,2907915 0,30261434 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,2907915 0,30248351 ! tRNA processing GO:0008033 89 61 0,000 0,2907915 0,30235279 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,2907915 0,30222219 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,29477927 0,30623442 ! gonad development GO:0008406 98 62 0,000 0,29477927 0,30610225 ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,29874474 0,31008622 ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,29874474 0,3099525 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,29874474 0,3098189 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,30268805 0,31377313 ! cell redox homeostasis GO:0045454 102 64 0,000 0,30268805 0,313638 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,30268805 0,31350299 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,30268805 0,31336809 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,30660931 0,31729118 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,30660931 0,31715477 ! germ cell development GO:0007281 118 65 0,000 0,30660931 0,31701848 ! myeloid cell differentiation GO:0030099 111 65 0,000 0,30660931 0,3168823 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,31050865 0,3207745 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,31050865 0,32063683 ! extracellular matrix organization GO:0030198 133 66 0,000 0,31050865 0,32049928 ! secondary metabolic process GO:0019748 116 66 0,000 0,31050865 0,32036184 ! cell projection assembly GO:0030031 120 66 0,000 0,31050865 0,32022453 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,3143862 0,32408449 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,3143862 0,32394569 ! hexose catabolic process GO:0019320 104 67 0,000 0,3143862 0,32380702 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,3143862 0,32366846 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,31824206 0,32749803 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,31824206 0,32735802 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,32207637 0,33116057 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,32207637 0,33101911 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,32207637 0,33087777 ! antigen processing and presentation GO:0019882 104 69 0,000 0,32207637 0,33073655 ! amine catabolic process GO:0009310 117 71 0,000 0,32968079 0,33840101 ! regulation of immune effector process GO:0002697 137 71 0,000 0,32968079 0,33825671 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 0,000 0,33345114 0,3419793 ! regulation of blood pressure GO:0008217 125 73 0,000 0,33720041 0,34567711 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,33720041 0,34552989 ! fertilization GO:0009566 90 73 0,000 0,33720041 0,34538279 ! transition metal ion transport GO:0000041 126 74 0,000 0,34092871 0,34905297 ! exocytosis GO:0006887 133 74 0,000 0,34092871 0,3489045 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,34092871 0,34875615 ! eye development GO:0001654 143 74 0,000 0,34092871 0,34860794 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,34463616 0,3522492 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,34463616 0,35209962 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,34832289 0,35571514 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,34832289 0,35556422 ! defense response to bacterium GO:0042742 89 76 0,000 0,34832289 0,35541343 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,34832289 0,35526276 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,34832289 0,35511223 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,35198899 0,3586978 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,35198899 0,35854594 ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,35563459 0,36210615 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,35563459 0,36195297 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,3592598 0,36548799 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,3592598 0,36533351 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,3592598 0,36517917 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,36286474 0,36868774 ! response to metal ion GO:0010038 140 80 0,000 0,36286474 0,36853211 ! muscle cell differentiation GO:0042692 159 80 0,000 0,36286474 0,36837661 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,36286474 0,36822124 ! inorganic anion transport GO:0015698 138 80 0,000 0,36286474 0,36806601 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,36644951 0,37154552 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,37001424 0,37500179 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,37001424 0,3748439 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,37001424 0,37468613 ! regulation of lyase activity GO:0051339 160 83 0,000 0,37355902 0,37811654 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,37708398 0,38152399 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,37708398 0,38136362 ! response to inorganic substance GO:0010035 153 86 0,000 0,38407484 0,38827062 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,38407484 0,38810755 ! alcohol catabolic process GO:0046164 130 86 0,000 0,38407484 0,38794462 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,38754097 0,3912814 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,38754097 0,39111728 ! cellular respiration GO:0045333 135 88 0,000 0,39098771 0,39443037 ! positive regulation of protein modification process GO:0031401 136 88 0,000 0,39098771 0,39426506 ! regulation of neurological system process GO:0031644 148 88 0,000 0,39098771 0,39409989 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,39098771 0,39393486 ! cellular defense response GO:0006968 114 89 0,000 0,39441517 0,39722181 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,39782345 0,4004867 ! sterol metabolic process GO:0016125 152 91 0,000 0,40121266 0,40372968 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,40121266 0,4035609 ! regulation of defense response GO:0031347 149 92 0,000 0,40458291 0,40678081 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,40458291 0,40661089 ! vitamin metabolic process GO:0006766 139 92 0,000 0,40458291 0,40644112 ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,4079343 0,40963686 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,4079343 0,40946597 ! female pregnancy GO:0007565 164 94 0,000 0,41126694 0,41263897 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,41787637 0,41909568 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,41787637 0,41892106 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,42115337 0,42203041 ! response to virus GO:0009615 160 98 0,000 0,42441204 0,4251188 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,42441204 0,42494189 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,42441204 0,42476512 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,42765246 0,42783028 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,42765246 0,42765246