pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6695-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! melatonin biosynthetic process GO:0030187 7 5 3,000 3,538E-09 8,643E-06 GO:0030186|melatonin metabolic process, ! indolalkylamine biosynthetic process GO:0046219 8 6 3,000 1,057E-08 1,291E-05 GO:0042435|indole derivative biosynthetic process, ! regulation of fibroblast proliferation GO:0048145 56 28 4,000 3,227E-07 2,628E-04 ! indolalkylamine metabolic process GO:0006586 19 13 3,000 4,896E-07 2,99E-04 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! positive regulation of glycolysis GO:0045821 13 5 2,000 1,377E-06 6,727E-04 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 4,000 4,171E-06 1,698E-03 ! prostate gland development GO:0030850 14 7 2,000 4,781E-06 1,669E-03 ! regulation of protein export from nucleus GO:0046825 10 7 2,000 4,781E-06 1,46E-03 ! ER overload response GO:0006983 13 8 2,000 7,621E-06 2,069E-03 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 2,000 7,621E-06 1,862E-03 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 2,000 7,621E-06 1,693E-03 ! positive regulation of fibroblast proliferation GO:0048146 48 25 3,000 8,25E-06 1,679E-03 ! insulin receptor signaling pathway GO:0008286 66 27 3,000 1,135E-05 2,133E-03 ! positive regulation of glucose metabolic process GO:0010907 18 9 2,000 1,139E-05 1,987E-03 ! regulation of glycolysis GO:0006110 20 9 2,000 1,139E-05 1,855E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 4,000 1,217E-05 1,857E-03 ! interphase of mitotic cell cycle GO:0051329 224 98 5,000 1,297E-05 1,864E-03 ! positive regulation of cell migration GO:0030335 137 58 4,000 1,326E-05 1,799E-03 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 2,000 1,621E-05 2,084E-03 GO:0043470|regulation of carbohydrate catabolic process, ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 2,000 1,621E-05 1,98E-03 ! regulation of homeostatic process GO:0032844 148 62 4,000 1,841E-05 2,142E-03 ! cell junction assembly GO:0034329 85 31 3,000 2,002E-05 2,224E-03 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 2,000 2,22E-05 2,358E-03 ! positive regulation of endothelial cell proliferation GO:0001938 23 11 2,000 2,22E-05 2,26E-03 ! positive regulation of catabolic process GO:0009896 72 32 3,000 2,279E-05 2,227E-03 ! positive regulation of cell motion GO:0051272 157 65 4,000 2,32E-05 2,18E-03 ! positive regulation of cellular catabolic process GO:0031331 34 12 2,000 2,948E-05 2,668E-03 ! biogenic amine biosynthetic process GO:0042401 65 35 3,000 3,279E-05 2,861E-03 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 2,000 3,818E-05 3,216E-03 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of monooxygenase activity GO:0032768 35 13 2,000 3,818E-05 3,109E-03 ! regulation of erythrocyte differentiation GO:0045646 47 13 2,000 3,818E-05 3,009E-03 ! cell junction organization GO:0034330 96 37 3,000 4,102E-05 3,132E-03 ! hormone biosynthetic process GO:0042446 62 37 3,000 4,102E-05 3,037E-03 ! cellular response to insulin stimulus GO:0032869 85 38 3,000 4,566E-05 3,281E-03 ! rhythmic process GO:0048511 142 75 4,000 4,649E-05 3,245E-03 ! release of cytochrome c from mitochondria GO:0001836 31 14 2,000 4,841E-05 3,285E-03 ! carbohydrate homeostasis GO:0033500 59 39 3,000 5,067E-05 3,346E-03 GO:0042593|glucose homeostasis, ! epithelial to mesenchymal transition GO:0001837 30 15 2,000 6,028E-05 3,875E-03 ! regulation of intracellular protein transport GO:0033157 86 42 3,000 6,812E-05 4,267E-03 ! regulation of glucose metabolic process GO:0010906 28 16 2,000 7,39E-05 4,514E-03 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 2,000 7,39E-05 4,404E-03 ! positive regulation of neuron apoptosis GO:0043525 32 16 2,000 7,39E-05 4,299E-03 ! neuron migration GO:0001764 85 43 3,000 7,48E-05 4,25E-03 ! regulation of epithelial cell proliferation GO:0050678 122 45 3,000 8,958E-05 4,974E-03 ! induction of apoptosis by intracellular signals GO:0008629 95 45 3,000 8,958E-05 4,863E-03 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 3,000 9,771E-05 5,19E-03 ! regulation of gene-specific transcription GO:0032583 102 46 3,000 9,771E-05 5,079E-03 ! response to insulin stimulus GO:0032868 98 47 3,000 1,064E-04 5,414E-03 ! cell-substrate junction assembly GO:0007044 56 18 2,000 1,069E-04 5,328E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 2,000 1,069E-04 5,222E-03 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 2,000 1,069E-04 5,119E-03 ! peptide cross-linking GO:0018149 39 19 2,000 1,264E-04 5,939E-03 ! positive regulation of MAP kinase activity GO:0043406 174 93 4,000 1,298E-04 5,983E-03 ! regulation of carbohydrate metabolic process GO:0006109 37 20 2,000 1,482E-04 6,703E-03 GO:0010675|regulation of cellular carbohydrate metabolic process, ! apoptotic mitochondrial changes GO:0008637 42 20 2,000 1,482E-04 6,581E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 2,000 1,722E-04 7,512E-03 ! negative regulation of intracellular transport GO:0032387 44 21 2,000 1,722E-04 7,38E-03 ! hormone metabolic process GO:0042445 171 100 4,000 1,826E-04 7,692E-03 ! regulation of angiogenesis GO:0045765 125 54 3,000 1,833E-04 7,591E-03 ! regulation of translational initiation GO:0006446 87 54 3,000 1,833E-04 7,464E-03 ! response to UV GO:0009411 120 55 3,000 1,969E-04 7,886E-03 ! regulation of intracellular transport GO:0032386 108 57 3,000 2,262E-04 8,914E-03 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 3,000 2,42E-04 9,384E-03 ! positive regulation of cell adhesion GO:0045785 61 24 2,000 2,59E-04 9,888E-03 ! regulation of cellular catabolic process GO:0031329 55 24 2,000 2,59E-04 9,736E-03 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 2,000 2,59E-04 9,589E-03 ! regulation of oxidoreductase activity GO:0051341 48 24 2,000 2,59E-04 9,446E-03 ! hemoglobin biosynthetic process GO:0042541 8 5 1,000 2,667E-04 9,581E-03 ! negative regulation of bone resorption GO:0045779 10 5 1,000 2,667E-04 9,442E-03 ! cell adhesion mediated by integrin GO:0033627 10 5 1,000 2,667E-04 9,307E-03 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 1,000 2,667E-04 9,176E-03 ! negative regulation of survival gene product expression GO:0008634 9 5 1,000 2,667E-04 9,049E-03 ! mRNA transcription GO:0009299 10 5 1,000 2,667E-04 8,925E-03 ! regulation of phospholipase A2 activity GO:0032429 15 5 1,000 2,667E-04 8,804E-03 ! meiotic chromosome segregation GO:0045132 10 5 1,000 2,667E-04 8,687E-03 ! positive regulation of chemokine production GO:0032722 8 5 1,000 2,667E-04 8,572E-03 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 1,000 2,667E-04 8,461E-03 ! protein insertion into membrane GO:0051205 17 5 1,000 2,667E-04 8,353E-03 ! protein tetramerization GO:0051262 57 25 2,000 2,932E-04 9,068E-03 ! response to endoplasmic reticulum stress GO:0034976 46 26 2,000 3,302E-04 0,01008436 ! protein amino acid autophosphorylation GO:0046777 157 64 3,000 3,537E-04 0,0106679 ! response to peptide hormone stimulus GO:0043434 129 64 3,000 3,537E-04 0,0105378 ! regulation of endothelial cell proliferation GO:0001936 60 27 2,000 3,701E-04 0,01089308 ! regulation of chromosome organization GO:0033044 49 27 2,000 3,701E-04 0,0107634 ! regulation of hormone biosynthetic process GO:0046885 10 6 1,000 3,986E-04 0,01145765 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 1,000 3,986E-04 0,01132442 ! embryonic hemopoiesis GO:0035162 16 6 1,000 3,986E-04 0,01119425 ! activation of MAPKKK activity GO:0000185 12 6 1,000 3,986E-04 0,01106705 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 1,000 3,986E-04 0,0109427 ! establishment of spindle localization GO:0051293 16 6 1,000 3,986E-04 0,01082111 GO:0051653|spindle localization, ! oxygen homeostasis GO:0032364 10 6 1,000 3,986E-04 0,0107022 ! negative regulation of neuroblast proliferation GO:0007406 25 6 1,000 3,986E-04 0,01058587 ! negative regulation of osteoblast differentiation GO:0045668 17 6 1,000 3,986E-04 0,01047204 ! cellular iron ion homeostasis GO:0006879 57 29 2,000 4,588E-04 0,01192396 ! ER-nuclear signaling pathway GO:0006984 52 29 2,000 4,588E-04 0,01179845 ! cellular hormone metabolic process GO:0034754 120 69 3,000 4,716E-04 0,01200179 ! lung development GO:0030324 165 69 3,000 4,716E-04 0,01187806 ! respiratory tube development GO:0030323 171 72 3,000 5,545E-04 0,01382251 ! B cell activation GO:0042113 179 72 3,000 5,545E-04 0,01368289 ! regulation of helicase activity GO:0051095 16 7 1,000 5,562E-04 0,01358787 ! neuron adhesion GO:0007158 14 7 1,000 5,562E-04 0,01345334 ! N-terminal protein amino acid acetylation GO:0006474 14 7 1,000 5,562E-04 0,01332145 ! mRNA stabilization GO:0048255 18 7 1,000 5,562E-04 0,01319211 GO:0043489|RNA stabilization, ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 1,000 5,562E-04 0,01306526 ! male sex determination GO:0030238 15 7 1,000 5,562E-04 0,01294083 ! wound healing, spreading of epidermal cells GO:0035313 16 7 1,000 5,562E-04 0,01281875 ! G1 DNA damage checkpoint GO:0031571 20 7 1,000 5,562E-04 0,01269895 ! B cell lineage commitment GO:0002326 21 7 1,000 5,562E-04 0,01258137 ! positive regulation of monooxygenase activity GO:0032770 12 7 1,000 5,562E-04 0,01246594 ! T cell lineage commitment GO:0002360 16 7 1,000 5,562E-04 0,01235261 ! axonal fasciculation GO:0007413 19 7 1,000 5,562E-04 0,01224133 ! iron ion homeostasis GO:0055072 60 31 2,000 5,601E-04 0,01221716 ! cellular response to extracellular stimulus GO:0031668 52 31 2,000 5,601E-04 0,01210905 ! respiratory system development GO:0060541 175 74 3,000 6,152E-04 0,01318277 ! positive regulation of gene-specific transcription GO:0043193 70 33 2,000 6,747E-04 0,01433229 ! negative regulation of protein transport GO:0051224 74 33 2,000 6,747E-04 0,01420874 ! learning or memory GO:0007611 161 76 3,000 6,804E-04 0,01420698 ! regulation of catabolic process GO:0009894 173 77 3,000 7,148E-04 0,01479858 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 1,000 7,391E-04 0,01517236 ! male meiosis GO:0007140 9 8 1,000 7,391E-04 0,01504592 ! neurotransmitter uptake GO:0001504 18 8 1,000 7,391E-04 0,01492157 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 1,000 7,391E-04 0,01479927 ! T-helper 1 type immune response GO:0042088 12 8 1,000 7,391E-04 0,01467895 ! hemoglobin metabolic process GO:0020027 14 8 1,000 7,391E-04 0,01456057 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 7,391E-04 0,01444408 ! positive regulation of endothelial cell migration GO:0010595 19 8 1,000 7,391E-04 0,01432945 ! regulation of vascular permeability GO:0043114 12 8 1,000 7,391E-04 0,01421662 ! regulation of T cell differentiation in the thymus GO:0033081 14 8 1,000 7,391E-04 0,01410555 ! gas homeostasis GO:0033483 14 8 1,000 7,391E-04 0,01399621 ! response to tumor cell GO:0002347 16 8 1,000 7,391E-04 0,01388854 ! regulation of respiratory burst GO:0060263 12 8 1,000 7,391E-04 0,01378252 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 1,000 7,391E-04 0,01367811 ! protein oligomerization GO:0051259 149 79 3,000 7,872E-04 0,01446016 ! placenta development GO:0001890 53 35 2,000 8,032E-04 0,01464286 ! response to hypoxia GO:0001666 178 81 3,000 8,647E-04 0,01564793 ! tissue remodeling GO:0048771 78 37 2,000 9,462E-04 0,01699757 ! induction of positive chemotaxis GO:0050930 17 9 1,000 9,47E-04 0,01688629 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 1,000 9,47E-04 0,01676393 ! microtubule bundle formation GO:0001578 22 9 1,000 9,47E-04 0,01664332 ! middle ear morphogenesis GO:0042474 14 9 1,000 9,47E-04 0,01652444 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 1,000 9,47E-04 0,01640725 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 1,000 9,47E-04 0,0162917 ! regulation of telomere maintenance GO:0032204 17 9 1,000 9,47E-04 0,01617778 ! response to oxygen levels GO:0070482 183 83 3,000 9,474E-04 0,01607291 ! negative regulation of growth GO:0045926 168 85 3,000 1,036E-03 0,01744655 ! cellular response to hormone stimulus GO:0032870 182 85 3,000 1,036E-03 0,01732705 ! mitochondrion organization GO:0007005 159 87 3,000 1,129E-03 0,01876655 ! regulation of protein transport GO:0051223 165 87 3,000 1,129E-03 0,01863975 GO:0070201|regulation of establishment of protein localization, ! amine biosynthetic process GO:0009309 146 88 3,000 1,178E-03 0,01931828 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 1,000 1,18E-03 0,01921253 ! regulation of developmental growth GO:0048638 16 10 1,000 1,18E-03 0,0190853 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 1,000 1,18E-03 0,01895974 ! positive regulation of B cell proliferation GO:0030890 18 10 1,000 1,18E-03 0,01883582 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 1,000 1,18E-03 0,01871351 ! lung alveolus development GO:0048286 26 10 1,000 1,18E-03 0,01859277 ! negative regulation of striated muscle development GO:0045843 26 10 1,000 1,18E-03 0,01847359 ! epithelial cell development GO:0002064 21 10 1,000 1,18E-03 0,01835592 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 1,000 1,18E-03 0,01823975 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 1,000 1,18E-03 0,01812503 ! motor axon guidance GO:0008045 22 10 1,000 1,18E-03 0,01801175 ! regulation of bone resorption GO:0045124 25 10 1,000 1,18E-03 0,01789988 ! protein heterooligomerization GO:0051291 17 10 1,000 1,18E-03 0,01778938 ! learning GO:0007612 82 40 2,000 1,19E-03 0,01782799 ! mesenchymal cell development GO:0014031 94 41 2,000 1,279E-03 0,0190454 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! gland development GO:0048732 220 91 3,000 1,334E-03 0,01975417 ! negative regulation of muscle development GO:0048635 27 11 1,000 1,437E-03 0,02114607 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 1,000 1,437E-03 0,02101944 ! detection of mechanical stimulus GO:0050982 22 11 1,000 1,437E-03 0,02089433 ! blood vessel remodeling GO:0001974 30 11 1,000 1,437E-03 0,02077069 ! peptide or protein amino-terminal blocking GO:0018409 22 11 1,000 1,437E-03 0,02064851 ! regulation of intracellular pH GO:0051453 21 11 1,000 1,437E-03 0,02052776 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 1,000 1,437E-03 0,02040841 ! nitric oxide metabolic process GO:0046209 17 11 1,000 1,437E-03 0,02029044 GO:0006809|nitric oxide biosynthetic process, ! positive regulation of leukocyte migration GO:0002687 28 11 1,000 1,437E-03 0,02017383 ! T cell receptor signaling pathway GO:0050852 29 11 1,000 1,437E-03 0,02005855 ! regulation of embryonic development GO:0045995 35 11 1,000 1,437E-03 0,01994458 ! regulation of myeloid cell differentiation GO:0045637 105 43 2,000 1,469E-03 0,02027413 ! regulation of DNA metabolic process GO:0051052 188 97 3,000 1,688E-03 0,02317234 ! biogenic amine metabolic process GO:0006576 162 97 3,000 1,688E-03 0,02304288 ! regulation of protein localization GO:0032880 188 97 3,000 1,688E-03 0,02291487 ! virus-host interaction GO:0019048 30 12 1,000 1,718E-03 0,02319277 ! regulation of B cell proliferation GO:0030888 22 12 1,000 1,718E-03 0,02306533 ! regulation of positive chemotaxis GO:0050926 22 12 1,000 1,718E-03 0,02293929 GO:0050927|positive regulation of positive chemotaxis, ! focal adhesion formation GO:0048041 37 12 1,000 1,718E-03 0,02281462 ! histone acetylation GO:0016573 27 12 1,000 1,718E-03 0,0226913 ! regulation of hormone metabolic process GO:0032350 28 12 1,000 1,718E-03 0,02256931 ! peptidyl-lysine modification GO:0018205 21 12 1,000 1,718E-03 0,02244861 ! regulation of leukocyte migration GO:0002685 29 12 1,000 1,718E-03 0,02232921 ! negative regulation of mast cell proliferation GO:0070667 24 12 1,000 1,718E-03 0,02221106 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 1,000 1,718E-03 0,02209416 ! embryonic placenta development GO:0001892 21 12 1,000 1,718E-03 0,02197849 ! localization within membrane GO:0051668 26 12 1,000 1,718E-03 0,02186401 ! positive regulation of cell cycle GO:0045787 96 48 2,000 2,02E-03 0,02556713 ! regulation of chemokine production GO:0032642 18 13 1,000 2,024E-03 0,02548549 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 1,000 2,024E-03 0,02535479 ! endocrine pancreas development GO:0031018 25 13 1,000 2,024E-03 0,02522543 ! response to X-ray GO:0010165 28 13 1,000 2,024E-03 0,02509738 ! L-glutamate transport GO:0015813 30 13 1,000 2,024E-03 0,02497063 GO:0015800|acidic amino acid transport, ! regulation of mRNA stability GO:0043488 32 13 1,000 2,024E-03 0,02484515 ! cytoplasmic sequestering of protein GO:0051220 25 13 1,000 2,024E-03 0,02472092 ! regulation of mast cell proliferation GO:0070666 89 49 2,000 2,143E-03 0,02605124 ! activation of caspase activity GO:0006919 95 50 2,000 2,272E-03 0,02747214 ! cell-cell junction assembly GO:0007043 32 14 1,000 2,353E-03 0,02831776 ! bone mineralization GO:0030282 18 14 1,000 2,353E-03 0,02817895 ! negative regulation of protein import into nucleus GO:0042308 33 14 1,000 2,353E-03 0,02804149 ! regulation of cellular pH GO:0030641 27 14 1,000 2,353E-03 0,02790536 ! response to gamma radiation GO:0010332 30 14 1,000 2,353E-03 0,02777055 ! regulation of RNA stability GO:0043487 33 14 1,000 2,353E-03 0,02763704 ! regulation of leukocyte proliferation GO:0070663 97 53 2,000 2,684E-03 0,03137502 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of neuron apoptosis GO:0043523 117 53 2,000 2,684E-03 0,03122562 ! N-terminal protein amino acid modification GO:0031365 30 15 1,000 2,706E-03 0,03132813 ! negative regulation of bone remodeling GO:0046851 34 15 1,000 2,706E-03 0,03118035 ! regulation of mRNA processing GO:0050684 26 15 1,000 2,706E-03 0,03103397 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 1,000 2,706E-03 0,03088895 ! G1/S transition checkpoint GO:0031575 37 15 1,000 2,706E-03 0,03074528 ! positive regulation of oxidoreductase activity GO:0051353 22 15 1,000 2,706E-03 0,03060294 ! synaptic transmission, cholinergic GO:0007271 24 15 1,000 2,706E-03 0,03046191 ! muscle maintenance GO:0046716 26 15 1,000 2,706E-03 0,03032218 ! regulation of cell shape GO:0008360 142 54 2,000 2,831E-03 0,03158339 ! cell recognition GO:0008037 98 55 2,000 2,983E-03 0,03312752 ! positive regulation of cell size GO:0045793 29 16 1,000 3,082E-03 0,03406679 ! heterophilic cell adhesion GO:0007157 43 16 1,000 3,082E-03 0,03391334 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 1,000 3,082E-03 0,03376126 ! L-amino acid transport GO:0015807 33 16 1,000 3,082E-03 0,03361054 ! DNA replication initiation GO:0006270 28 16 1,000 3,082E-03 0,03346116 ! neuron recognition GO:0008038 40 16 1,000 3,082E-03 0,0333131 ! negative regulation of tissue remodeling GO:0034104 37 16 1,000 3,082E-03 0,03316635 ! biomineral formation GO:0031214 22 16 1,000 3,082E-03 0,03302088 ! negative regulation of leukocyte proliferation GO:0070664 32 16 1,000 3,082E-03 0,03287669 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! regulation of DNA replication GO:0006275 105 56 2,000 3,14E-03 0,03335383 ! regulation of bone remodeling GO:0046850 143 57 2,000 3,302E-03 0,0349215 ! positive regulation of caspase activity GO:0043280 108 57 2,000 3,302E-03 0,03477098 GO:0010952|positive regulation of peptidase activity, ! heart morphogenesis GO:0003007 105 57 2,000 3,302E-03 0,03462175 ! regulation of tissue remodeling GO:0034103 146 58 2,000 3,469E-03 0,03621637 ! negative regulation of cell cycle process GO:0010948 35 17 1,000 3,481E-03 0,03618501 ! embryonic forelimb morphogenesis GO:0035115 31 17 1,000 3,481E-03 0,03603168 ! activation of MAPKK activity GO:0000186 43 17 1,000 3,481E-03 0,03587965 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 1,000 3,481E-03 0,03572889 ! regulation of survival gene product expression GO:0045884 38 17 1,000 3,481E-03 0,0355794 ! negative regulation of microtubule depolymerization GO:0007026 50 17 1,000 3,481E-03 0,03543115 GO:0031114|regulation of microtubule depolymerization, ! DNA fragmentation involved in apoptosis GO:0006309 27 17 1,000 3,481E-03 0,03528413 ! negative regulation of homeostatic process GO:0032845 36 17 1,000 3,481E-03 0,03513833 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 1,000 3,481E-03 0,03499373 ! heart looping GO:0001947 34 18 1,000 3,902E-03 0,03907285 ! response to retinoic acid GO:0032526 31 18 1,000 3,902E-03 0,03891337 ! neural crest cell migration GO:0001755 41 18 1,000 3,902E-03 0,03875519 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 1,000 3,902E-03 0,03859829 ! positive regulation of translation GO:0045727 31 19 1,000 4,347E-03 0,0428188 ! G1 phase of mitotic cell cycle GO:0000080 39 19 1,000 4,347E-03 0,04264684 ! protein amino acid ADP-ribosylation GO:0006471 37 19 1,000 4,347E-03 0,04247625 ! memory GO:0007613 34 19 1,000 4,347E-03 0,04230702 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 1,000 4,347E-03 0,04213914 ! response to vitamin A GO:0033189 32 19 1,000 4,347E-03 0,04197258 ! neuromuscular junction development GO:0007528 43 19 1,000 4,347E-03 0,04180733 ! regulation of endothelial cell migration GO:0010594 45 19 1,000 4,347E-03 0,04164338 ! regulation of mitosis GO:0007088 112 63 2,000 4,381E-03 0,04180338 GO:0051783|regulation of nuclear division, ! positive regulation of angiogenesis GO:0045766 50 20 1,000 4,813E-03 0,04575386 ! phosphoinositide phosphorylation GO:0046854 40 20 1,000 4,813E-03 0,04557652 ! protein amino acid acetylation GO:0006473 41 20 1,000 4,813E-03 0,04540055 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 1,000 4,813E-03 0,04522593 ! response to vitamin GO:0033273 36 20 1,000 4,813E-03 0,04505265 ! forelimb morphogenesis GO:0035136 35 20 1,000 4,813E-03 0,04488069 ! response to alkaloid GO:0043279 38 20 1,000 4,813E-03 0,04471005 ! pancreas development GO:0031016 40 20 1,000 4,813E-03 0,04454069 ! peptidyl-serine phosphorylation GO:0018105 44 20 1,000 4,813E-03 0,04437261 ! actin filament bundle formation GO:0051017 47 20 1,000 4,813E-03 0,0442058 ! cell-cell junction organization GO:0045216 43 20 1,000 4,813E-03 0,04404023 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 1,000 4,813E-03 0,0438759 ! negative regulation of T cell activation GO:0050868 41 20 1,000 4,813E-03 0,0437128 ! negative regulation of cell growth GO:0030308 142 67 2,000 5,205E-03 0,04709476 ! activation of MAPK activity GO:0000187 124 67 2,000 5,205E-03 0,04692098 ! lipid phosphorylation GO:0046834 43 21 1,000 5,302E-03 0,04761847 ! cell structure disassembly during apoptosis GO:0006921 32 21 1,000 5,302E-03 0,04744404 ! plasma membrane fusion GO:0045026 33 21 1,000 5,302E-03 0,04727089 ! negative regulation of angiogenesis GO:0016525 49 21 1,000 5,302E-03 0,047099 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 1,000 5,302E-03 0,04692835 ! adaptive immune response GO:0002250 126 68 2,000 5,425E-03 0,04784174 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! negative regulation of cell size GO:0045792 144 69 2,000 5,65E-03 0,04964806 ! negative regulation of protein kinase activity GO:0006469 144 69 2,000 5,65E-03 0,04947011 ! urogenital system development GO:0001655 149 69 2,000 5,65E-03 0,04929343 ! positive regulation of protein catabolic process GO:0045732 44 22 1,000 5,812E-03 0,05052998 ! hindlimb morphogenesis GO:0035137 47 22 1,000 5,812E-03 0,0503508 ! glutamate signaling pathway GO:0007215 48 22 1,000 5,812E-03 0,05017288 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 1,000 5,812E-03 0,04999621 ! cellular response to starvation GO:0009267 37 22 1,000 5,812E-03 0,04982079 ! apoptotic nuclear changes GO:0030262 34 22 1,000 5,812E-03 0,04964659 ! cell aging GO:0007569 48 22 1,000 5,812E-03 0,04947361 ! cytolysis GO:0019835 27 22 1,000 5,812E-03 0,04930182 ! positive regulation of locomotion GO:0040017 44 22 1,000 5,812E-03 0,04913123 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! G1 phase GO:0051318 44 22 1,000 5,812E-03 0,04896181 ! positive regulation of intracellular transport GO:0032388 42 22 1,000 5,812E-03 0,04879356 ! peptidyl-serine modification GO:0018209 50 22 1,000 5,812E-03 0,04862645 ! positive regulation of B cell activation GO:0050871 42 22 1,000 5,812E-03 0,04846049 ! activation of JUN kinase activity GO:0007257 47 22 1,000 5,812E-03 0,04829566 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 1,000 5,812E-03 0,04813195 ! negative regulation of kinase activity GO:0033673 145 70 2,000 5,88E-03 0,04853268 ! activation of immune response GO:0002253 120 70 2,000 5,88E-03 0,04836927 ! cell cycle checkpoint GO:0000075 145 71 2,000 6,117E-03 0,05014357 ! positive regulation of DNA replication GO:0045740 44 23 1,000 6,344E-03 0,05183366 ! regulation of chemotaxis GO:0050920 45 23 1,000 6,344E-03 0,05166088 ! axis specification GO:0009798 43 23 1,000 6,344E-03 0,05148925 ! regulation of cell-matrix adhesion GO:0001952 81 23 1,000 6,344E-03 0,05131875 GO:0010810|regulation of cell-substrate adhesion, ! activation of pro-apoptotic gene products GO:0008633 51 23 1,000 6,344E-03 0,05114938 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 1,000 6,344E-03 0,05098113 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 1,000 6,344E-03 0,05081398 ! acute inflammatory response GO:0002526 118 74 2,000 6,859E-03 0,05475986 ! regulation of caspase activity GO:0043281 136 74 2,000 6,859E-03 0,05458149 ! negative regulation of transferase activity GO:0051348 155 74 2,000 6,859E-03 0,05440428 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 1,000 6,897E-03 0,05452966 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 1,000 6,897E-03 0,05435376 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! sex determination GO:0007530 48 24 1,000 6,897E-03 0,05417899 ! negative regulation of phosphorylation GO:0042326 52 24 1,000 6,897E-03 0,05400534 ! platelet activation GO:0030168 41 24 1,000 6,897E-03 0,05383279 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 1,000 6,897E-03 0,05366135 ! reproductive structure development GO:0048608 131 75 2,000 7,118E-03 0,05520262 ! axon guidance GO:0007411 162 75 2,000 7,118E-03 0,05502793 ! protein import into nucleus, translocation GO:0000060 51 25 1,000 7,471E-03 0,05757905 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 1,000 7,471E-03 0,05739798 ! leukocyte adhesion GO:0007159 55 25 1,000 7,471E-03 0,05721805 ! vasculogenesis GO:0001570 49 25 1,000 7,471E-03 0,05703924 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 1,000 7,471E-03 0,05686155 ! negative regulation of DNA replication GO:0008156 45 25 1,000 7,471E-03 0,05668496 ! regulation of behavior GO:0050795 48 25 1,000 7,471E-03 0,05650947 ! interaction with host GO:0051701 66 25 1,000 7,471E-03 0,05633505 ! liver development GO:0001889 55 25 1,000 7,471E-03 0,05616171 ! regulation of endopeptidase activity GO:0052548 141 77 2,000 7,653E-03 0,05734812 ! myelination GO:0042552 50 26 1,000 8,066E-03 0,06026414 ! regulation of transcription factor import into nucleus GO:0042990 58 26 1,000 8,066E-03 0,06008041 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 1,000 8,066E-03 0,0598978 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 1,000 8,066E-03 0,05971629 GO:0045936|negative regulation of phosphate metabolic process, ! neural crest cell development GO:0014032 59 26 1,000 8,066E-03 0,05953588 GO:0014033|neural crest cell differentiation, ! negative regulation of cell development GO:0010721 83 26 1,000 8,066E-03 0,05935655 GO:0050768|negative regulation of neurogenesis, ! positive regulation of nuclear division GO:0051785 41 26 1,000 8,066E-03 0,0591783 GO:0045840|positive regulation of mitosis, ! regulation of osteoblast differentiation GO:0045667 68 26 1,000 8,066E-03 0,05900112 ! neural tube closure GO:0001843 58 26 1,000 8,066E-03 0,058825 GO:0060606|tube closure, ! positive regulation of JUN kinase activity GO:0043507 59 26 1,000 8,066E-03 0,05864992 ! negative regulation of organelle organization GO:0010639 181 80 2,000 8,498E-03 0,06160717 ! tube lumen formation GO:0035148 59 27 1,000 8,682E-03 0,06275312 ! mitochondrial membrane organization GO:0007006 60 27 1,000 8,682E-03 0,06256801 ! response to starvation GO:0042594 47 27 1,000 8,682E-03 0,06238398 ! response to toxin GO:0009636 49 27 1,000 8,682E-03 0,06220104 ! cellular response to oxidative stress GO:0034599 43 27 1,000 8,682E-03 0,06201917 ! cellular response to nutrient levels GO:0031669 45 27 1,000 8,682E-03 0,06183835 ! negative regulation of lymphocyte activation GO:0051250 55 27 1,000 8,682E-03 0,06165859 ! meiosis GO:0007126 143 81 2,000 8,792E-03 0,06225765 GO:0051327|M phase of meiotic cell cycle, ! regulation of peptidase activity GO:0052547 150 82 2,000 9,092E-03 0,06419234 ! cell-substrate adhesion GO:0031589 189 82 2,000 9,092E-03 0,06400735 ! meiotic cell cycle GO:0051321 144 82 2,000 9,092E-03 0,06382342 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 1,000 9,318E-03 0,06522791 ! protein amino acid acylation GO:0043543 59 28 1,000 9,318E-03 0,06504154 ! circadian rhythm GO:0007623 56 28 1,000 9,318E-03 0,06485624 ! dendrite development GO:0016358 67 28 1,000 9,318E-03 0,06467199 ! base-excision repair GO:0006284 41 28 1,000 9,318E-03 0,06448878 ! peptidyl-tyrosine modification GO:0018212 57 28 1,000 9,318E-03 0,06430661 ! regulation of JUN kinase activity GO:0043506 67 28 1,000 9,318E-03 0,06412546 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 1,000 9,975E-03 0,06844881 ! primary neural tube formation GO:0014020 61 29 1,000 9,975E-03 0,06825707 ! somitogenesis GO:0001756 52 29 1,000 9,975E-03 0,06806641 ! negative regulation of transport GO:0051051 164 85 2,000 0,01002554 0,06822397 ! acute-phase response GO:0006953 50 30 1,000 0,01065072 0,07227698 ! complement activation, classical pathway GO:0006958 51 30 1,000 0,01065072 0,07207677 ! immune response-activating signal transduction GO:0002757 58 30 1,000 0,01065072 0,07187766 GO:0002764|immune response-regulating signal transduction, ! tissue homeostasis GO:0001894 50 30 1,000 0,01065072 0,07167965 GO:0048871|multicellular organismal homeostasis, ! regulation of B cell activation GO:0050864 55 30 1,000 0,01065072 0,07148273 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 1,000 0,01134663 0,07594468 ! ensheathment of neurons GO:0007272 64 31 1,000 0,01134663 0,07573719 GO:0008366|axon ensheathment, ! negative regulation of leukocyte activation GO:0002695 60 31 1,000 0,01134663 0,07553082 ! response to heat GO:0009408 54 31 1,000 0,01134663 0,07532557 ! tube morphogenesis GO:0035239 194 89 2,000 0,0113547 0,07517491 ! regulation of DNA binding GO:0051101 167 89 2,000 0,0113547 0,07497173 ! response to unfolded protein GO:0006986 139 90 2,000 0,01170208 0,07705711 ! regulation of cell cycle process GO:0010564 161 90 2,000 0,01170208 0,07684997 ! ossification GO:0001503 205 91 2,000 0,01205553 0,0789589 ! collagen metabolic process GO:0032963 49 32 1,000 0,01206202 0,07879017 ! spindle organization GO:0007051 50 32 1,000 0,01206202 0,07858006 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 1,000 0,01206202 0,07837107 ! response to mechanical stimulus GO:0009612 60 32 1,000 0,01206202 0,07816319 ! regulation of protein import into nucleus GO:0042306 69 32 1,000 0,01206202 0,07795641 ! peripheral nervous system development GO:0007422 68 32 1,000 0,01206202 0,07775072 ! bone development GO:0060348 206 92 2,000 0,01241507 0,07981584 ! regulation of cell adhesion GO:0030155 241 92 2,000 0,01241507 0,07960635 ! regulation of cell morphogenesis GO:0022604 243 93 2,000 0,01278071 0,08173634 ! regulation of pH GO:0006885 56 33 1,000 0,01279669 0,08162485 ! response to ionizing radiation GO:0010212 74 33 1,000 0,01279669 0,08141228 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 1,000 0,01355041 0,08598353 ! response to protein stimulus GO:0051789 158 96 2,000 0,0139144 0,08806444 ! DNA damage checkpoint GO:0000077 78 35 1,000 0,01432297 0,09041609 ! negative regulation of DNA metabolic process GO:0051053 65 35 1,000 0,01432297 0,09018305 ! regulation of striated muscle tissue development GO:0016202 81 35 1,000 0,01432297 0,08995122 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 1,000 0,01432297 0,08972058 ! calcium-mediated signaling GO:0019722 67 35 1,000 0,01432297 0,08949111 ! regulation of muscle development GO:0048634 82 36 1,000 0,01511416 0,09419359 ! mitotic sister chromatid segregation GO:0000070 63 36 1,000 0,01511416 0,09395391 ! negative regulation of DNA binding GO:0043392 67 36 1,000 0,01511416 0,09371545 ! negative regulation of hydrolase activity GO:0051346 66 36 1,000 0,01511416 0,0934782 ! embryonic organ development GO:0048568 67 36 1,000 0,01511416 0,09324214 ! skeletal muscle tissue development GO:0007519 223 100 2,000 0,01551222 0,09545684 GO:0060538|skeletal muscle organ development, ! positive regulation of immune response GO:0050778 175 100 2,000 0,01551222 0,095217 ! regulation of smooth muscle cell proliferation GO:0048660 64 37 1,000 0,01592375 0,09749807 ! xenobiotic metabolic process GO:0006805 55 37 1,000 0,01592375 0,09725432 ! sister chromatid segregation GO:0000819 65 37 1,000 0,01592375 0,09701179 ! maintenance of protein location in cell GO:0032507 89 37 1,000 0,01592375 0,09677047 ! androgen receptor signaling pathway GO:0030521 81 37 1,000 0,01592375 0,09653034 ! regulation of microtubule-based process GO:0032886 86 37 1,000 0,01592375 0,09629141 ! negative regulation of cell activation GO:0050866 69 37 1,000 0,01592375 0,09605365 ! positive regulation of DNA metabolic process GO:0051054 77 38 1,000 0,01675155 0,10079811 ! meiosis I GO:0007127 74 38 1,000 0,01675155 0,10055045 ! organic anion transport GO:0015711 82 38 1,000 0,01675155 0,100304 ! DNA integrity checkpoint GO:0031570 82 38 1,000 0,01675155 0,10005876 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 1,000 0,01675155 0,09981471 ! glycogen metabolic process GO:0005977 63 38 1,000 0,01675155 0,09957186 ! neural tube formation GO:0001841 79 38 1,000 0,01675155 0,09933018 ! negative regulation of binding GO:0051100 71 39 1,000 0,01759733 0,10409271 ! mitotic cell cycle checkpoint GO:0007093 76 39 1,000 0,01759733 0,10384128 ! positive regulation of leukocyte proliferation GO:0070665 70 39 1,000 0,01759733 0,10359106 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! glucan metabolic process GO:0044042 64 39 1,000 0,01759733 0,10334204 GO:0006073|cellular glucan metabolic process, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 1,000 0,0184609 0,10815346 GO:0006956|complement activation, ! mammary gland development GO:0030879 93 40 1,000 0,0184609 0,10789471 ! nucleus organization GO:0006997 73 40 1,000 0,0184609 0,10763721 ! regulation of action potential in neuron GO:0019228 80 40 1,000 0,0184609 0,10738093 ! Rho protein signal transduction GO:0007266 88 40 1,000 0,0184609 0,10712587 ! gliogenesis GO:0042063 91 41 1,000 0,01934205 0,11197307 ! feeding behavior GO:0007631 69 41 1,000 0,01934205 0,11170835 ! multicellular organismal metabolic process GO:0044236 64 41 1,000 0,01934205 0,11144489 ! monovalent inorganic cation homeostasis GO:0055067 72 41 1,000 0,01934205 0,11118267 ! maintenance of protein location GO:0045185 95 41 1,000 0,01934205 0,11092168 ! embryonic epithelial tube formation GO:0001838 85 41 1,000 0,01934205 0,11066191 ! ear morphogenesis GO:0042471 64 42 1,000 0,02024057 0,11553206 ! T cell differentiation GO:0030217 93 42 1,000 0,02024057 0,11526275 ! regulation of T cell differentiation GO:0045580 78 42 1,000 0,02024057 0,1149947 ! dorsal/ventral pattern formation GO:0009953 75 42 1,000 0,02024057 0,11472789 ! cytokinesis GO:0000910 84 42 1,000 0,02024057 0,11446232 ! response to xenobiotic stimulus GO:0009410 63 42 1,000 0,02024057 0,11419797 ! positive regulation of transcription factor activity GO:0051091 71 43 1,000 0,02115626 0,1190893 GO:0090047|positive regulation of transcription regulator activity, ! epithelial cell differentiation GO:0030855 83 43 1,000 0,02115626 0,11881553 ! calcium-dependent cell-cell adhesion GO:0016339 56 43 1,000 0,02115626 0,11854301 ! glucose transport GO:0015758 66 43 1,000 0,02115626 0,11827175 ! regulation of T cell proliferation GO:0042129 80 43 1,000 0,02115626 0,11800172 ! segmentation GO:0035282 78 43 1,000 0,02115626 0,11773293 ! energy reserve metabolic process GO:0006112 76 44 1,000 0,02208893 0,12264374 ! negative regulation of protein complex disassembly GO:0043242 113 44 1,000 0,02208893 0,12236564 ! positive regulation of response to external stimulus GO:0032103 88 44 1,000 0,02208893 0,12208879 ! hexose transport GO:0008645 68 44 1,000 0,02208893 0,12181319 GO:0015749|monosaccharide transport, ! double-strand break repair GO:0006302 85 44 1,000 0,02208893 0,12153884 ! branching morphogenesis of a tube GO:0048754 102 45 1,000 0,02303836 0,12647799 ! keratinocyte differentiation GO:0030216 81 45 1,000 0,02303836 0,12619441 ! B cell differentiation GO:0030183 124 45 1,000 0,02303836 0,12591209 ! maintenance of location in cell GO:0051651 101 45 1,000 0,02303836 0,12563104 ! negative regulation of cell migration GO:0030336 122 46 1,000 0,02400436 0,13060724 ! pigmentation GO:0043473 103 46 1,000 0,02400436 0,13031701 ! cell growth GO:0016049 90 46 1,000 0,02400436 0,13002805 ! positive regulation of protein transport GO:0051222 80 46 1,000 0,02400436 0,12974038 ! neural tube development GO:0021915 91 47 1,000 0,02498674 0,13475189 ! regulation of JNK cascade GO:0046328 104 47 1,000 0,02498674 0,13445508 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 0,02575602 0,13829003 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 0,02575602 0,13798676 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 0,02575602 0,13768482 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,02575602 0,1373842 ! positive regulation of helicase activity GO:0051096 12 5 0,000 0,02575602 0,13708489 ! neuron fate determination GO:0048664 7 5 0,000 0,02575602 0,13678687 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02575602 0,13649016 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 0,02575602 0,13619472 ! polyol transport GO:0015791 12 5 0,000 0,02575602 0,13590057 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,02575602 0,13560768 ! response to superoxide GO:0000303 10 5 0,000 0,02575602 0,13531605 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 0,02575602 0,13502567 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 0,02575602 0,13473654 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,02575602 0,13444864 ! female meiosis GO:0007143 10 5 0,000 0,02575602 0,13416197 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,02575602 0,13387652 ! hypothalamus development GO:0021854 9 5 0,000 0,02575602 0,13359228 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 0,02575602 0,13330924 ! cobalt ion transport GO:0006824 11 5 0,000 0,02575602 0,1330274 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 0,02575602 0,13274676 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 0,02575602 0,13246729 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,02575602 0,132189 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,02575602 0,13191187 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 0,02575602 0,1316359 ! embryonic camera-type eye development GO:0031076 12 5 0,000 0,02575602 0,13136109 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,02575602 0,13108742 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02575602 0,13081489 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 0,02575602 0,13054349 ! transposition GO:0032196 9 5 0,000 0,02575602 0,13027321 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 0,02575602 0,13000405 ! negative chemotaxis GO:0050919 16 5 0,000 0,02575602 0,129736 ! positive regulation of histone modification GO:0031058 6 5 0,000 0,02575602 0,12946906 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,02575602 0,12920321 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 0,02575602 0,12893845 ! behavioral response to pain GO:0048266 10 5 0,000 0,02575602 0,12867477 ! clathrin coat assembly GO:0048268 15 5 0,000 0,02575602 0,12841217 ! Notch receptor processing GO:0007220 11 5 0,000 0,02575602 0,12815064 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02575602 0,12789017 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 0,02575602 0,12763076 ! micturition GO:0060073 9 5 0,000 0,02575602 0,12737239 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,02575602 0,12711508 ! copulation GO:0007620 9 5 0,000 0,02575602 0,12685879 ! glial cell fate commitment GO:0021781 14 5 0,000 0,02575602 0,12660355 ! protein maturation by protein folding GO:0022417 14 5 0,000 0,02575602 0,12634932 ! bioluminescence GO:0008218 9 5 0,000 0,02575602 0,12609612 ! spermidine metabolic process GO:0008216 7 5 0,000 0,02575602 0,12584392 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,02575602 0,12559274 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,02575602 0,12534255 ! apoptotic cell clearance GO:0043277 23 5 0,000 0,02575602 0,12509336 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,02575602 0,12484516 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 0,02575602 0,12459795 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,02575602 0,1243517 ! grooming behavior GO:0007625 6 5 0,000 0,02575602 0,12410643 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 0,02575602 0,12386213 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,02575602 0,12361879 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 0,02575602 0,1233764 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02575602 0,12313496 ! response to protozoan GO:0001562 13 5 0,000 0,02575602 0,12289446 ! lymph vessel development GO:0001945 10 5 0,000 0,02575602 0,1226549 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 0,02575602 0,12241627 ! endochondral ossification GO:0001958 17 5 0,000 0,02575602 0,12217857 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,02575602 0,12194179 ! single strand break repair GO:0000012 8 5 0,000 0,02575602 0,12170592 ! parathyroid gland development GO:0060017 14 5 0,000 0,02575602 0,12147097 ! anagen GO:0042640 7 5 0,000 0,02575602 0,12123692 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,02575602 0,12100377 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,02575602 0,12077152 ! cytokine secretion GO:0050663 15 5 0,000 0,02575602 0,12054016 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 0,02575602 0,12030968 ! ceramide catabolic process GO:0046514 7 5 0,000 0,02575602 0,12008008 ! skeletal myofibril assembly GO:0014866 12 5 0,000 0,02575602 0,11985136 ! smooth muscle tissue development GO:0048745 32 5 0,000 0,02575602 0,1196235 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,02575602 0,11939651 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,02575602 0,11917038 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,02575602 0,11894511 ! cardiac muscle fiber development GO:0048739 12 5 0,000 0,02575602 0,11872068 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,02575602 0,1184971 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,02575602 0,11827437 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 0,02575602 0,11805246 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,02575602 0,11783139 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 0,02575602 0,11761114 ! glycine biosynthetic process GO:0006545 7 5 0,000 0,02575602 0,11739172 ! microvillus organization GO:0032528 8 5 0,000 0,02575602 0,11717311 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 12 5 0,000 0,02575602 0,11695532 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 0,02575602 0,11673833 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 0,02575602 0,11652215 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 0,02575602 0,11630677 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 0,02575602 0,11609218 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 0,02575602 0,11587838 ! polyol catabolic process GO:0046174 9 5 0,000 0,02575602 0,11566537 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 0,02575602 0,11545314 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 0,02575602 0,11524169 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 0,02575602 0,11503101 ! muscle cell migration GO:0014812 8 5 0,000 0,02575602 0,1148211 ! mitochondrial fission GO:0000266 8 5 0,000 0,02575602 0,11461195 ! sister chromatid cohesion GO:0007062 15 5 0,000 0,02575602 0,11440357 ! response to tumor necrosis factor GO:0034612 10 5 0,000 0,02575602 0,11419594 ! nerve growth factor processing GO:0032455 9 5 0,000 0,02575602 0,11398906 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 0,02575602 0,11378293 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 0,02575602 0,11357755 ! anaerobic glycolysis GO:0019642 6 5 0,000 0,02575602 0,1133729 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,02575602 0,113169 ! monocyte activation GO:0042117 10 5 0,000 0,02575602 0,11296582 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,02575602 0,11276337 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,02575602 0,11256165 ! response to food GO:0032094 6 5 0,000 0,02575602 0,11236065 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,02575602 0,11216036 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,02575602 0,11196079 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 0,02575602 0,11176192 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02575602 0,11156376 ! forebrain neuron development GO:0021884 13 5 0,000 0,02575602 0,1113663 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,02575602 0,11116954 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 0,02575602 0,11097348 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 0,02575602 0,1107781 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,02575602 0,11058341 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02575602 0,11038941 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 0,02575602 0,11019608 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,02575602 0,11000343 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 0,02575602 0,10981145 ! lipid glycosylation GO:0030259 7 5 0,000 0,02575602 0,10962014 ! nucleobase transport GO:0015851 6 5 0,000 0,02575602 0,1094295 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02575602 0,10923952 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 0,02575602 0,10905019 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 0,02575602 0,10886153 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 0,02575602 0,10867351 ! basic amino acid transport GO:0015802 12 5 0,000 0,02575602 0,10848614 ! cellular glucose homeostasis GO:0001678 6 5 0,000 0,02575602 0,10829942 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 0,02575602 0,10811334 ! actin nucleation GO:0045010 11 5 0,000 0,02575602 0,10792789 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,02575602 0,10774309 ! depurination GO:0045007 5 5 0,000 0,02575602 0,10755891 ! depyrimidination GO:0045008 10 5 0,000 0,02575602 0,10737536 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,02575602 0,10719244 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02575602 0,10701014 ! G2/M transition checkpoint GO:0031576 8 5 0,000 0,02575602 0,10682846 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,02575602 0,10664739 ! zinc ion homeostasis GO:0055069 9 5 0,000 0,02575602 0,10646694 GO:0006882|cellular zinc ion homeostasis, ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 0,02575602 0,1062871 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02575602 0,10610786 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,02575602 0,10592923 ! activated T cell proliferation GO:0050798 16 5 0,000 0,02575602 0,1057512 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,02575602 0,10557376 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 0,02575602 0,10539692 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,02575602 0,10522067 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02575602 0,10504501 ! gamma-delta T cell activation GO:0046629 6 5 0,000 0,02575602 0,10486994 ! response to arsenic GO:0046685 11 5 0,000 0,02575602 0,10469544 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 0,02575602 0,10452153 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,02575602 0,1043482 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 0,02575602 0,10417543 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 0,02575602 0,10400324 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 0,02575602 0,10383162 ! response to mercury ion GO:0046689 8 5 0,000 0,02575602 0,10366056 ! response to cadmium ion GO:0046686 7 5 0,000 0,02575602 0,10349007 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 0,02575602 0,10332014 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 0,02575602 0,10315076 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 0,02575602 0,10298193 ! bile acid biosynthetic process GO:0006699 7 5 0,000 0,02575602 0,10281366 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 0,02575602 0,10264594 ! ganglioside catabolic process GO:0006689 12 5 0,000 0,02575602 0,10247877 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,02575602 0,10231213 ! decidualization GO:0046697 11 5 0,000 0,02575602 0,10214604 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 0,02575602 0,10198049 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 0,02575602 0,10181547 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 0,02575602 0,10165099 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 0,02575602 0,10148704 ! embryonic cleavage GO:0040016 6 5 0,000 0,02575602 0,10132361 ! peroxisome fission GO:0016559 5 5 0,000 0,02575602 0,10116071 ! histone demethylation GO:0016577 13 5 0,000 0,02575602 0,10099833 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 0,02575602 0,10083648 ! mitotic recombination GO:0006312 9 5 0,000 0,02575602 0,10067514 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 0,02575602 0,10051432 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,02575602 0,10035401 ! metaphase plate congression GO:0051310 7 5 0,000 0,02575602 0,10019421 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02575602 0,10003492 GO:0032374|regulation of cholesterol transport, ! enteric nervous system development GO:0048484 8 5 0,000 0,02575602 0,09987613 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 0,02575602 0,09971785 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 0,02575602 0,09956007 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 0,02575602 0,09940278 ! muscle cell proliferation GO:0033002 12 5 0,000 0,02575602 0,099246 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,02575602 0,0990897 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 0,02575602 0,0989339 ! B cell homeostasis GO:0001782 13 5 0,000 0,02575602 0,09877859 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 0,02575602 0,09862377 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,02575602 0,09846942 ! metaphase GO:0051323 11 5 0,000 0,02575602 0,09831557 ! positive regulation of blood coagulation GO:0030194 12 5 0,000 0,02575602 0,09816219 ! cellular response to nutrient GO:0031670 8 5 0,000 0,02575602 0,09800929 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,02575602 0,09785686 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 0,02575602 0,09770491 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 0,02575602 0,09755343 ! regulation of hair follicle development GO:0051797 10 5 0,000 0,02575602 0,09740242 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 0,02575602 0,09725187 ! response to redox state GO:0051775 6 5 0,000 0,02575602 0,09710179 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 0,02575602 0,09695218 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 0,02575602 0,09680302 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,02575602 0,09665432 ! brown fat cell differentiation GO:0050873 7 5 0,000 0,02575602 0,09650608 ! regulation of telomerase activity GO:0051972 7 5 0,000 0,02575602 0,09635829 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02575602 0,09621095 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 0,02575602 0,09606406 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02575602 0,09591763 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 0,02575602 0,09577163 ! striatum development GO:0021756 14 5 0,000 0,02575602 0,09562608 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 0,02575602 0,09548097 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,02575602 0,09533631 ! glial cell migration GO:0008347 10 5 0,000 0,02575602 0,09519208 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,02575602 0,09504828 ! neural plate morphogenesis GO:0001839 7 5 0,000 0,02575602 0,09490492 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 0,02575602 0,09476199 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,02575602 0,09461949 ! T cell activation during immune response GO:0002286 9 5 0,000 0,02575602 0,09447742 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,02575602 0,09433578 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,02575602 0,09419455 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 0,02575602 0,09405376 ! neuroprotection GO:0043526 8 5 0,000 0,02575602 0,09391338 ! regulation of sensory perception GO:0051931 8 5 0,000 0,02575602 0,09377342 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,02575602 0,09363387 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,02575602 0,09349474 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 0,02575602 0,09335603 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 0,02575602 0,09321772 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,02575602 0,09307983 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 0,02575602 0,09294234 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,02575602 0,09280525 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 0,02575602 0,09266857 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 0,02575602 0,0925323 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,02575602 0,09239642 ! spindle assembly GO:0051225 6 5 0,000 0,02575602 0,09226094 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,02575602 0,09212586 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,02575602 0,09199117 ! protein palmitoylation GO:0018345 12 5 0,000 0,02575602 0,09185688 ! drug metabolic process GO:0017144 7 5 0,000 0,02575602 0,09172298 ! stem cell division GO:0017145 11 5 0,000 0,02575602 0,09158946 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,02575602 0,09145634 ! organ regeneration GO:0031100 7 5 0,000 0,02575602 0,0913236 ! carnitine metabolic process GO:0009437 8 5 0,000 0,02575602 0,09119125 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,02575602 0,09105928 ! mitochondrial transport GO:0006839 94 48 1,000 0,0259853 0,09173713 ! cellular component disassembly GO:0022411 89 48 1,000 0,0259853 0,09160475 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 1,000 0,0259853 0,09147275 ! positive regulation of DNA binding GO:0043388 83 48 1,000 0,0259853 0,09134114 ! vascular process in circulatory system GO:0003018 85 48 1,000 0,0259853 0,0912099 ! detection of stimulus involved in sensory perception GO:0050906 75 49 1,000 0,02699985 0,09463506 ! regulation of lymphocyte differentiation GO:0045619 92 49 1,000 0,02699985 0,09449948 ! JNK cascade GO:0007254 106 49 1,000 0,02699985 0,09436428 ! protein homooligomerization GO:0051260 84 49 1,000 0,02699985 0,09422948 ! regulation of action potential GO:0001508 102 50 1,000 0,0280302 0,09768584 ! endocrine system development GO:0035270 109 50 1,000 0,0280302 0,09754668 ! regulation of ossification GO:0030278 123 50 1,000 0,0280302 0,09740792 ! immunoglobulin mediated immune response GO:0016064 89 50 1,000 0,0280302 0,09726956 GO:0019724|B cell mediated immunity, ! epidermal cell differentiation GO:0009913 87 50 1,000 0,0280302 0,09713159 ! positive regulation of cytokine production GO:0001819 94 50 1,000 0,0280302 0,09699401 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 1,000 0,02907615 0,10047105 ! response to temperature stimulus GO:0009266 84 51 1,000 0,02907615 0,10032914 ! detection of abiotic stimulus GO:0009582 80 51 1,000 0,02907615 0,10018764 ! negative regulation of immune system process GO:0002683 101 51 1,000 0,02907615 0,10004653 ! positive regulation of binding GO:0051099 88 52 1,000 0,03013752 0,10355269 ! regulation of protein complex disassembly GO:0043244 127 52 1,000 0,03013752 0,10340725 ! morphogenesis of embryonic epithelium GO:0016331 106 52 1,000 0,03013752 0,10326222 ! DNA-dependent DNA replication GO:0006261 82 52 1,000 0,03013752 0,1031176 ! histone modification GO:0016570 104 52 1,000 0,03013752 0,10297338 ! morphogenesis of a branching structure GO:0001763 116 52 1,000 0,03013752 0,10282956 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,0308275 0,10503706 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,0308275 0,10489077 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 0,0308275 0,10474489 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 0,0308275 0,10459941 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,0308275 0,10445433 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 0,0308275 0,10430966 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 0,0308275 0,10416539 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,0308275 0,10402151 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 0,0308275 0,10387803 ! response to oxygen radical GO:0000305 11 6 0,000 0,0308275 0,10373495 ! positive regulation of axon extension GO:0045773 13 6 0,000 0,0308275 0,10359226 ! myoblast cell fate commitment GO:0048625 18 6 0,000 0,0308275 0,10344997 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 0,0308275 0,10330806 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 0,0308275 0,10316654 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,0308275 0,10302541 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 0,0308275 0,10288466 ! forebrain regionalization GO:0021871 9 6 0,000 0,0308275 0,1027443 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,0308275 0,10260433 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,0308275 0,10246473 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 0,0308275 0,10232551 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,0308275 0,10218667 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 0,0308275 0,1020482 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,0308275 0,10191011 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 0,0308275 0,1017724 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 0,0308275 0,10163505 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,0308275 0,10149808 ! malate metabolic process GO:0006108 13 6 0,000 0,0308275 0,10136147 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 0,0308275 0,10122523 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 0,0308275 0,10108936 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 0,0308275 0,10095385 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 0,0308275 0,10081871 ! protein refolding GO:0042026 15 6 0,000 0,0308275 0,10068392 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,0308275 0,1005495 ! opsonization GO:0008228 8 6 0,000 0,0308275 0,10041543 ! mating behavior GO:0007617 7 6 0,000 0,0308275 0,10028172 ! erythrocyte maturation GO:0043249 8 6 0,000 0,0308275 0,10014837 ! protein amino acid dealkylation GO:0008214 15 6 0,000 0,0308275 0,10001537 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 0,0308275 0,09988273 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 0,0308275 0,09975043 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,0308275 0,09961849 ! response to interferon-gamma GO:0034341 16 6 0,000 0,0308275 0,09948689 ! toxin metabolic process GO:0009404 11 6 0,000 0,0308275 0,09935564 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,0308275 0,09922474 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 0,0308275 0,09909418 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 0,0308275 0,09896396 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 0,0308275 0,09883409 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 13 6 0,000 0,0308275 0,09870455 ! cGMP-mediated signaling GO:0019934 14 6 0,000 0,0308275 0,09857536 ! dorsal spinal cord development GO:0021516 10 6 0,000 0,0308275 0,0984465 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 0,0308275 0,09831798 ! thymic T cell selection GO:0045061 16 6 0,000 0,0308275 0,0981898 ! sphingoid catabolic process GO:0046521 8 6 0,000 0,0308275 0,09806195 ! protein lipoylation GO:0009249 10 6 0,000 0,0308275 0,09793443 ! transepithelial chloride transport GO:0030321 12 6 0,000 0,0308275 0,09780724 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 0,0308275 0,09768038 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,0308275 0,09755385 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 0,0308275 0,09742765 ! glutamate catabolic process GO:0006538 12 6 0,000 0,0308275 0,09730178 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 0,0308275 0,09717623 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,0308275 0,097051 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 0,0308275 0,09692609 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,0308275 0,09680151 ! hyperosmotic response GO:0006972 10 6 0,000 0,0308275 0,09667725 ! L-serine biosynthetic process GO:0006564 7 6 0,000 0,0308275 0,0965533 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 0,0308275 0,09642967 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 0,0308275 0,09630636 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,0308275 0,09618336 ! urea metabolic process GO:0019627 7 6 0,000 0,0308275 0,09606068 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,0308275 0,09593831 ! neutrophil activation GO:0042119 7 6 0,000 0,0308275 0,09581625 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,0308275 0,0956945 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 0,0308275 0,09557306 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,0308275 0,09545193 ! paraxial mesoderm development GO:0048339 16 6 0,000 0,0308275 0,09533111 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 0,0308275 0,09521059 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,0308275 0,09509037 ! neuron apoptosis GO:0051402 15 6 0,000 0,0308275 0,09497046 ! T cell mediated immunity GO:0002456 17 6 0,000 0,0308275 0,09485085 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,0308275 0,09473154 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 0,0308275 0,09461253 ! carnitine transport GO:0015879 10 6 0,000 0,0308275 0,09449382 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,0308275 0,09437541 ! positive regulation of exocytosis GO:0045921 11 6 0,000 0,0308275 0,09425729 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 0,0308275 0,09413947 ! early endosome to late endosome transport GO:0045022 16 6 0,000 0,0308275 0,09402194 ! 5S class rRNA transcription GO:0042791 13 6 0,000 0,0308275 0,09390471 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,0308275 0,09378776 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 0,0308275 0,09367111 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 0,0308275 0,09355475 ! sodium ion homeostasis GO:0055078 12 6 0,000 0,0308275 0,09343868 ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 0,0308275 0,09332289 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,0308275 0,09320739 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 0,000 0,0308275 0,09309218 ! response to UV-C GO:0010225 14 6 0,000 0,0308275 0,09297725 ! astrocyte development GO:0014002 16 6 0,000 0,0308275 0,09286261 ! protein targeting to lysosome GO:0006622 12 6 0,000 0,0308275 0,09274824 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,0308275 0,09263416 ! interaction with symbiont GO:0051702 14 6 0,000 0,0308275 0,09252036 ! regulation of dendrite development GO:0050773 16 6 0,000 0,0308275 0,09240684 ! peptidyl-arginine modification GO:0018195 13 6 0,000 0,0308275 0,0922936 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 0,0308275 0,09218063 ! response to copper ion GO:0046688 10 6 0,000 0,0308275 0,09206794 ! response to exogenous dsRNA GO:0043330 13 6 0,000 0,0308275 0,09195552 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 0,0308275 0,09184338 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,0308275 0,09173152 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 0,0308275 0,09161992 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,0308275 0,0915086 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 0,0308275 0,09139754 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,0308275 0,09128676 ! nucleoside catabolic process GO:0009164 10 6 0,000 0,0308275 0,09117624 ! hair follicle maturation GO:0048820 8 6 0,000 0,0308275 0,09106599 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,0308275 0,09095601 ! Schwann cell development GO:0014044 15 6 0,000 0,0308275 0,09084629 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 0,0308275 0,09073684 ! response to pheromone GO:0019236 6 6 0,000 0,0308275 0,09062765 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 0,0308275 0,09051872 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 0,0308275 0,09041005 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 0,0308275 0,09030165 ! base conversion or substitution editing GO:0016553 6 6 0,000 0,0308275 0,0901935 ! subpallium development GO:0021544 15 6 0,000 0,0308275 0,09008562 ! neural tube patterning GO:0021532 8 6 0,000 0,0308275 0,08997799 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 0,0308275 0,08987061 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 0,0308275 0,0897635 ! maintenance of organ identity GO:0048496 9 6 0,000 0,0308275 0,08965664 ! G2 phase GO:0051319 16 6 0,000 0,0308275 0,08955003 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,0308275 0,08944368 ! establishment of planar polarity GO:0001736 7 6 0,000 0,0308275 0,08933757 ! regulation of mast cell activation GO:0033003 13 6 0,000 0,0308275 0,08923172 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,0308275 0,08912612 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 0,0308275 0,08902077 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,0308275 0,08891567 ! receptor internalization GO:0031623 11 6 0,000 0,0308275 0,08881082 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 0,0308275 0,08870621 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 0,0308275 0,08860185 ! neutrophil homeostasis GO:0001780 11 6 0,000 0,0308275 0,08849774 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,0308275 0,08839387 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 0,0308275 0,08829024 ! protein deubiquitination GO:0016579 16 6 0,000 0,0308275 0,08818686 ! protein destabilization GO:0031648 9 6 0,000 0,0308275 0,08808371 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 0,0308275 0,08798081 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 0,0308275 0,08787815 ! regulation of viral transcription GO:0046782 11 6 0,000 0,0308275 0,08777573 ! progesterone metabolic process GO:0042448 12 6 0,000 0,0308275 0,08767354 ! negative regulation of axon extension GO:0030517 24 6 0,000 0,0308275 0,0875716 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 0,0308275 0,08746989 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 0,0308275 0,08736842 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,0308275 0,08726718 ! determination of adult lifespan GO:0008340 17 6 0,000 0,0308275 0,08716617 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 0,0308275 0,0870654 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 0,0308275 0,08696487 ! neural plate development GO:0001840 9 6 0,000 0,0308275 0,08686456 ! catecholamine transport GO:0051937 9 6 0,000 0,0308275 0,08676449 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 0,0308275 0,08666464 ! sensory cilium assembly GO:0035058 10 6 0,000 0,0308275 0,08656503 ! organ or tissue specific immune response GO:0002251 8 6 0,000 0,0308275 0,08646564 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 0,0308275 0,08636648 ! maternal placenta development GO:0001893 12 6 0,000 0,0308275 0,08626755 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 0,0308275 0,08616885 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,0308275 0,08607037 ! negative regulation of B cell activation GO:0050869 14 6 0,000 0,0308275 0,08597212 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 0,0308275 0,08587409 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 0,0308275 0,08577628 ! positive regulation of coagulation GO:0050820 13 6 0,000 0,0308275 0,0856787 ! cellular anion homeostasis GO:0030002 11 6 0,000 0,0308275 0,08558133 GO:0055081|anion homeostasis, ! positive regulation of growth GO:0045927 96 53 1,000 0,03121412 0,08655631 ! cartilage development GO:0051216 99 53 1,000 0,03121412 0,08645817 ! synapse organization GO:0050808 102 53 1,000 0,03121412 0,08636026 ! activation of phospholipase C activity GO:0007202 110 54 1,000 0,03230577 0,08927942 GO:0010863|positive regulation of phospholipase C activity, ! membrane fusion GO:0006944 122 54 1,000 0,03230577 0,08917853 ! covalent chromatin modification GO:0016569 115 54 1,000 0,03230577 0,08907788 ! epithelial tube morphogenesis GO:0060562 114 54 1,000 0,03230577 0,08897746 ! positive regulation of phospholipase activity GO:0010518 111 55 1,000 0,03341228 0,09192141 ! cell maturation GO:0048469 107 55 1,000 0,03341228 0,09181801 ! negative regulation of cell motion GO:0051271 142 55 1,000 0,03341228 0,09171484 ! skeletal muscle fiber development GO:0048741 130 56 1,000 0,03453347 0,09468606 ! negative regulation of cytoskeleton organization GO:0051494 139 56 1,000 0,03453347 0,09457991 ! regulation of protein catabolic process GO:0042176 126 56 1,000 0,03453347 0,09447399 ! muscle fiber development GO:0048747 131 57 1,000 0,03566916 0,09747177 ! nucleotide-excision repair GO:0006289 91 57 1,000 0,03566916 0,09736286 ! regulation of phospholipase activity GO:0010517 113 57 1,000 0,03566916 0,0972542 ! tRNA transcription GO:0009304 17 7 0,000 0,03587271 0,09770016 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 0,03587271 0,09759136 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 0,03587271 0,0974828 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,03587271 0,09737449 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 0,03587271 0,09726641 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,03587271 0,09715858 ! sleep GO:0030431 16 7 0,000 0,03587271 0,09705098 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,03587271 0,09694363 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 0,03587271 0,09683651 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,03587271 0,09672962 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,03587271 0,09662298 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,03587271 0,09651656 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,03587271 0,09641038 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,03587271 0,09630444 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,03587271 0,09619873 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,03587271 0,09609324 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,03587271 0,09598799 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,03587271 0,09588298 ! SMAD protein complex assembly GO:0007183 13 7 0,000 0,03587271 0,09577818 ! glycolipid transport GO:0046836 11 7 0,000 0,03587271 0,09567362 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,03587271 0,09556929 GO:0051923|sulfation, ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,03587271 0,09546518 ! establishment of tissue polarity GO:0007164 8 7 0,000 0,03587271 0,0953613 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 0,03587271 0,09525765 ! pericardium development GO:0060039 16 7 0,000 0,03587271 0,09515422 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 0,03587271 0,09505102 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 0,03587271 0,09494804 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 0,03587271 0,09484528 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 0,03587271 0,09474275 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,03587271 0,09464043 ! lipoprotein transport GO:0042953 14 7 0,000 0,03587271 0,09453834 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,03587271 0,09443646 ! rhythmic behavior GO:0007622 17 7 0,000 0,03587271 0,09433481 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 0,03587271 0,09423338 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 0,03587271 0,09413216 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,03587271 0,09403116 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 0,03587271 0,09393037 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,03587271 0,09382981 ! regulation of odontogenesis GO:0042481 14 7 0,000 0,03587271 0,09372945 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,03587271 0,09362932 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 0,03587271 0,09352939 ! mechanosensory behavior GO:0007638 16 7 0,000 0,03587271 0,09342968 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 0,03587271 0,09333018 ! positive regulation of isotype switching GO:0045830 17 7 0,000 0,03587271 0,09323089 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 0,03587271 0,09313182 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,03587271 0,09303295 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,03587271 0,09293429 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,03587271 0,09283585 ! spinal cord patterning GO:0021511 14 7 0,000 0,03587271 0,09273761 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 0,03587271 0,09263958 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,03587271 0,09254175 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,03587271 0,09244413 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 0,03587271 0,09234672 ! adrenal gland development GO:0030325 17 7 0,000 0,03587271 0,09224951 ! cysteine metabolic process GO:0006534 13 7 0,000 0,03587271 0,09215251 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 0,03587271 0,09205571 ! ovulation GO:0030728 10 7 0,000 0,03587271 0,09195912 ! adenohypophysis development GO:0021984 11 7 0,000 0,03587271 0,09186272 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 0,03587271 0,09176653 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 0,03587271 0,09167054 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 0,03587271 0,09157475 ! microtubule nucleation GO:0007020 21 7 0,000 0,03587271 0,09147916 ! proline biosynthetic process GO:0006561 10 7 0,000 0,03587271 0,09138377 ! tryptophan metabolic process GO:0006568 11 7 0,000 0,03587271 0,09128858 ! thyroid hormone generation GO:0006590 13 7 0,000 0,03587271 0,09119359 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 0,03587271 0,09109879 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,03587271 0,09100419 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,03587271 0,09090979 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,03587271 0,09081558 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,03587271 0,09072157 ! galactose metabolic process GO:0006012 13 7 0,000 0,03587271 0,09062776 ! vesicle fusion GO:0006906 20 7 0,000 0,03587271 0,09053413 ! response to dietary excess GO:0002021 8 7 0,000 0,03587271 0,0904407 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,03587271 0,09034746 ! intracellular pH reduction GO:0051452 13 7 0,000 0,03587271 0,09025442 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,03587271 0,09016156 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 0,03587271 0,0900689 ! organ growth GO:0035265 15 7 0,000 0,03587271 0,08997643 ! nucleoside transport GO:0015858 11 7 0,000 0,03587271 0,08988414 ! nucleoside salvage GO:0043174 11 7 0,000 0,03587271 0,08979205 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 0,03587271 0,08970014 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,03587271 0,08960842 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 0,03587271 0,08951689 ! parturition GO:0007567 16 7 0,000 0,03587271 0,08942555 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 0,03587271 0,08933439 ! rRNA modification GO:0000154 14 7 0,000 0,03587271 0,08924342 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,03587271 0,08915263 ! spindle checkpoint GO:0031577 16 7 0,000 0,03587271 0,08906203 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,03587271 0,08897161 ! monocyte differentiation GO:0030224 16 7 0,000 0,03587271 0,08888138 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,03587271 0,08879133 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,03587271 0,08870146 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 0,03587271 0,08861177 ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,03587271 0,08852226 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,03587271 0,08843294 ! fibrinolysis GO:0042730 11 7 0,000 0,03587271 0,08834379 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 0,000 0,03587271 0,08825482 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,03587271 0,08816604 ! eating behavior GO:0042755 8 7 0,000 0,03587271 0,08807743 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,03587271 0,087989 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 0,03587271 0,08790074 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 0,03587271 0,08781266 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,03587271 0,08772476 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 0,03587271 0,08763704 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,03587271 0,08754949 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 0,03587271 0,08746211 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 0,03587271 0,08737491 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 0,03587271 0,08728789 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 0,03587271 0,08720103 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,03587271 0,08711435 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 0,03587271 0,08702784 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,03587271 0,08694151 ! histone ubiquitination GO:0016574 9 7 0,000 0,03587271 0,08685534 ! regulation of meiosis GO:0040020 12 7 0,000 0,03587271 0,08676935 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 0,03587271 0,08668352 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 0,03587271 0,08659786 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,03587271 0,08651238 ! membrane to membrane docking GO:0022614 14 7 0,000 0,03587271 0,08642706 ! transcription termination GO:0006353 14 7 0,000 0,03587271 0,08634191 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,03587271 0,08625693 ! anaphase GO:0051322 18 7 0,000 0,03587271 0,08617211 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 0,03587271 0,08608746 ! negative regulation of nuclear division GO:0051784 15 7 0,000 0,03587271 0,08600298 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 0,03587271 0,08591867 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,03587271 0,08583451 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 0,03587271 0,08575053 ! diuresis GO:0030146 12 7 0,000 0,03587271 0,08566671 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,03587271 0,08558305 ! thiamin metabolic process GO:0006772 7 7 0,000 0,03587271 0,08549955 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,03587271 0,08541622 ! antibiotic transport GO:0042891 9 7 0,000 0,03587271 0,08533305 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,03587271 0,08525004 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 0,03587271 0,08516719 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 0,03587271 0,0850845 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 0,03587271 0,08500198 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,03587271 0,08491961 ! melanin biosynthetic process GO:0042438 10 7 0,000 0,03587271 0,0848374 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 0,03587271 0,08475536 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,03587271 0,08467347 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,03587271 0,08459174 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 0,03587271 0,08451016 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,03587271 0,08442875 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 0,03587271 0,08434749 ! endosome to lysosome transport GO:0008333 12 7 0,000 0,03587271 0,08426638 ! protein modification by small protein removal GO:0070646 19 7 0,000 0,03587271 0,08418544 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 0,03587271 0,08410464 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,03587271 0,08402401 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 0,03587271 0,08394352 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,03587271 0,0838632 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,03587271 0,08378302 ! muscle adaptation GO:0043500 13 7 0,000 0,03587271 0,083703 ! embryonic heart tube development GO:0035050 14 7 0,000 0,03587271 0,08362313 ! retina homeostasis GO:0001895 12 7 0,000 0,03587271 0,08354341 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 0,03587271 0,08346385 ! protein amino acid prenylation GO:0018346 19 7 0,000 0,03587271 0,08338443 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 0,03587271 0,08330517 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 0,03587271 0,08322606 ! cellular polysaccharide metabolic process GO:0044264 93 58 1,000 0,03681917 0,08534083 ! aging GO:0007568 112 58 1,000 0,03681917 0,08525994 ! positive regulation of organelle organization GO:0010638 108 58 1,000 0,03681917 0,0851792 ! positive regulation of lipase activity GO:0060193 115 58 1,000 0,03681917 0,08509861 ! maintenance of location GO:0051235 124 58 1,000 0,03681917 0,08501818 ! establishment of organelle localization GO:0051656 122 59 1,000 0,03798332 0,08762346 ! regulation of neurotransmitter levels GO:0001505 113 60 1,000 0,03916143 0,09025602 ! lipid modification GO:0030258 112 60 1,000 0,03916143 0,09017095 ! DNA catabolic process GO:0006308 94 60 1,000 0,03916143 0,09008604 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,04089181 0,09397807 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,04089181 0,09388974 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 0,04089181 0,09380158 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 0,04089181 0,09371359 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,04089181 0,09362576 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,04089181 0,0935381 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,04089181 0,0934506 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,04089181 0,09336326 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,04089181 0,09327608 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,04089181 0,09318907 ! meiotic prophase I GO:0007128 14 8 0,000 0,04089181 0,09310222 ! response to zinc ion GO:0010043 12 8 0,000 0,04089181 0,09301554 ! regulation of lipid kinase activity GO:0043550 17 8 0,000 0,04089181 0,09292901 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,04089181 0,09284265 ! oligopeptide transport GO:0006857 16 8 0,000 0,04089181 0,09275644 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,04089181 0,0926704 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,04089181 0,09258451 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,04089181 0,09249878 ! signal peptide processing GO:0006465 12 8 0,000 0,04089181 0,09241322 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,04089181 0,09232781 GO:0046457|prostanoid biosynthetic process, ! macrophage chemotaxis GO:0048246 12 8 0,000 0,04089181 0,09224255 ! succinate metabolic process GO:0006105 17 8 0,000 0,04089181 0,09215746 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,04089181 0,09207252 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,04089181 0,09198774 ! estrogen metabolic process GO:0008210 17 8 0,000 0,04089181 0,09190312 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,04089181 0,09181865 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,04089181 0,09173433 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,04089181 0,09165017 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,04089181 0,09156617 ! reflex GO:0060004 17 8 0,000 0,04089181 0,09148231 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,04089181 0,09139861 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,04089181 0,09131507 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,04089181 0,09123168 ! pigment granule organization GO:0048753 17 8 0,000 0,04089181 0,09114844 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,04089181 0,09106535 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,04089181 0,09098241 ! astrocyte differentiation GO:0048708 19 8 0,000 0,04089181 0,09089962 ! histidine catabolic process GO:0006548 10 8 0,000 0,04089181 0,09081699 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,04089181 0,0907345 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,04089181 0,09065217 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,04089181 0,09056998 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,04089181 0,09048794 ! regulation of pigmentation during development GO:0048070 25 8 0,000 0,04089181 0,09040605 ! melanin metabolic process GO:0006582 17 8 0,000 0,04089181 0,09032431 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,04089181 0,09024272 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,04089181 0,09016127 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,04089181 0,09007997 ! macrophage activation GO:0042116 13 8 0,000 0,04089181 0,08999882 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,04089181 0,08991781 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,04089181 0,08983695 ! positive regulation of insulin secretion GO:0032024 17 8 0,000 0,04089181 0,08975623 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,04089181 0,08967566 ! purine salvage GO:0043101 12 8 0,000 0,04089181 0,08959523 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,04089181 0,08951495 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,04089181 0,08943481 ! osteoblast development GO:0002076 17 8 0,000 0,04089181 0,08935482 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,04089181 0,08927497 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,04089181 0,08919526 ! Schwann cell differentiation GO:0014037 21 8 0,000 0,04089181 0,08911569 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,04089181 0,08903626 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,04089181 0,08895698 ! response to UV-B GO:0010224 17 8 0,000 0,04089181 0,08887783 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,04089181 0,08879883 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,04089181 0,08871997 ! intermediate filament organization GO:0045109 12 8 0,000 0,04089181 0,08864125 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,04089181 0,08856267 ! cellular extravasation GO:0045123 13 8 0,000 0,04089181 0,08848422 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,04089181 0,08840592 ! response to antibiotic GO:0046677 11 8 0,000 0,04089181 0,08832775 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,04089181 0,08824972 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,04089181 0,08817183 ! DNA topological change GO:0006265 12 8 0,000 0,04089181 0,08809408 ! response to tropane GO:0014073 15 8 0,000 0,04089181 0,08801646 GO:0042220|response to cocaine, ! melanosome transport GO:0032402 13 8 0,000 0,04089181 0,08793898 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,04089181 0,08786164 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,04089181 0,08778443 ! mast cell activation GO:0045576 14 8 0,000 0,04089181 0,08770736 ! multicellular organismal aging GO:0010259 20 8 0,000 0,04089181 0,08763043 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 0,04089181 0,08755363 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,04089181 0,08747696 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,04089181 0,08740043 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,04089181 0,08732403 ! nucleosome disassembly GO:0006337 14 8 0,000 0,04089181 0,08724776 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,04089181 0,08717163 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 0,04089181 0,08709563 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,04089181 0,08701976 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,04089181 0,08694403 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,04089181 0,08686842 ! intracellular lipid transport GO:0032365 16 8 0,000 0,04089181 0,08679295 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,04089181 0,08671761 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,04089181 0,0866424 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,04089181 0,08656732 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 0,04089181 0,08649237 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,04089181 0,08641755 ! hormone catabolic process GO:0042447 17 8 0,000 0,04089181 0,08634286 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,04089181 0,0862683 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,04089181 0,08619386 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,04089181 0,08611956 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,04089181 0,08604538 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,04089181 0,08597133 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,04089181 0,08589741 ! adult feeding behavior GO:0008343 10 8 0,000 0,04089181 0,08582361 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,04089181 0,08574995 ! ATP catabolic process GO:0006200 11 8 0,000 0,04089181 0,0856764 ! blastocyst growth GO:0001832 19 8 0,000 0,04089181 0,08560299 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,04089181 0,0855297 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,04089181 0,08545653 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,04089181 0,08538349 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,04089181 0,08531058 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,04089181 0,08523779 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,04089181 0,08516512 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,04089181 0,08509258 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,04089181 0,08502016 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,04089181 0,08494786 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 0,04089181 0,08487569 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,04089181 0,08480364 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 0,04089181 0,08473171 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,04089181 0,0846599 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,04089181 0,08458822 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 0,04089181 0,08451665 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 0,04089181 0,08444521 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,04089181 0,08437389 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 0,04089181 0,08430269 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 0,04089181 0,08423161 ! viral reproductive process GO:0022415 132 62 1,000 0,04155885 0,08553351 ! DNA damage response, signal transduction GO:0042770 136 62 1,000 0,04155885 0,08546151 ! mesoderm development GO:0007498 128 63 1,000 0,04277781 0,08789419 ! skeletal system morphogenesis GO:0048705 118 63 1,000 0,04277781 0,08782033 ! integrin-mediated signaling pathway GO:0007229 160 64 1,000 0,04401005 0,09027418 ! lymphocyte mediated immunity GO:0002449 122 65 1,000 0,04525538 0,09275075 ! axon extension GO:0048675 16 9 0,000 0,04588491 0,09396215 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,04588491 0,09388345 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 0,04588491 0,09380489 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,04588491 0,09372646 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,04588491 0,09364816 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,04588491 0,09356999 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,04588491 0,09349195 ! reproductive behavior GO:0019098 22 9 0,000 0,04588491 0,09341404 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,04588491 0,09333626 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 0,04588491 0,09325861 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 0,04588491 0,09318108 ! UTP metabolic process GO:0046051 10 9 0,000 0,04588491 0,09310369 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,04588491 0,09302643 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,04588491 0,09294929 ! artery development GO:0060840 25 9 0,000 0,04588491 0,09287228 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,04588491 0,0927954 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,04588491 0,09271865 ! equilibrioception GO:0050957 20 9 0,000 0,04588491 0,09264202 ! chemosensory behavior GO:0007635 21 9 0,000 0,04588491 0,09256552 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,04588491 0,09248915 ! leukocyte degranulation GO:0043299 16 9 0,000 0,04588491 0,0924129 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,04588491 0,09233677 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,04588491 0,09226078 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,04588491 0,0921849 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,04588491 0,09210916 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,04588491 0,09203353 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,04588491 0,09195803 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,04588491 0,09188266 ! protein targeting to ER GO:0045047 25 9 0,000 0,04588491 0,09180741 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,04588491 0,09173228 ! T cell selection GO:0045058 27 9 0,000 0,04588491 0,09165727 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,04588491 0,09158239 ! glycine catabolic process GO:0006546 15 9 0,000 0,04588491 0,09150763 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,04588491 0,09143299 ! endosome organization GO:0007032 20 9 0,000 0,04588491 0,09135847 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,04588491 0,09128408 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,04588491 0,0912098 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,04588491 0,09113565 ! mannose metabolic process GO:0006013 13 9 0,000 0,04588491 0,09106161 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,04588491 0,0909877 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,04588491 0,0909139 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 0,04588491 0,09084023 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,04588491 0,09076668 ! receptor clustering GO:0043113 20 9 0,000 0,04588491 0,09069324 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,04588491 0,09061992 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,04588491 0,09054672 ! retinol metabolic process GO:0042572 20 9 0,000 0,04588491 0,09047364 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,04588491 0,09040068 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,04588491 0,09032784 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,04588491 0,09025511 ! macrophage differentiation GO:0030225 15 9 0,000 0,04588491 0,0901825 ! oligodendrocyte development GO:0014003 11 9 0,000 0,04588491 0,09011 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 0,04588491 0,09003763 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,04588491 0,08996536 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,04588491 0,08989322 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,04588491 0,08982119 ! response to amine stimulus GO:0014075 13 9 0,000 0,04588491 0,08974927 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,04588491 0,08967748 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,04588491 0,08960579 ! erythrocyte development GO:0048821 17 9 0,000 0,04588491 0,08953422 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,04588491 0,08946276 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,04588491 0,08939142 ! renal water homeostasis GO:0003091 15 9 0,000 0,04588491 0,08932019 ! postreplication repair GO:0006301 25 9 0,000 0,04588491 0,08924908 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,04588491 0,08917808 ! icosanoid secretion GO:0032309 15 9 0,000 0,04588491 0,08910719 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,04588491 0,08903641 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,04588491 0,08896575 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,04588491 0,0888952 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,04588491 0,08882476 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,04588491 0,08875443 ! sterol catabolic process GO:0016127 14 9 0,000 0,04588491 0,08868421 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,04588491 0,08861411 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,04588491 0,08854411 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,04588491 0,08847423 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,04588491 0,08840445 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 0,04588491 0,08833479 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,04588491 0,08826523 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 0,04588491 0,08819579 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,04588491 0,08812645 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,04588491 0,08805722 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,04588491 0,0879881 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,04588491 0,08791909 ! purine base metabolic process GO:0006144 25 9 0,000 0,04588491 0,08785019 ! pigment granule transport GO:0051904 17 9 0,000 0,04588491 0,0877814 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,04588491 0,08771271 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,04588491 0,08764413 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,04588491 0,08757566 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,04588491 0,08750729 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,04588491 0,08743904 ! mitochondrion localization GO:0051646 18 9 0,000 0,04588491 0,08737088 ! steroid hormone receptor signaling pathway GO:0030518 146 66 1,000 0,04651365 0,08849911 ! ear development GO:0043583 114 66 1,000 0,04651365 0,08843024 ! embryonic limb morphogenesis GO:0030326 139 67 1,000 0,04778469 0,09077605 GO:0035113|embryonic appendage morphogenesis, ! chromosome segregation GO:0007059 127 67 1,000 0,04778469 0,09070552 ! regulation of cellular response to stress GO:0080135 142 68 1,000 0,04906833 0,09306983 ! detection of external stimulus GO:0009581 102 68 1,000 0,04906833 0,09299762 ! viral reproduction GO:0016032 142 68 1,000 0,04906833 0,09292553 ! regulation of lipase activity GO:0060191 137 68 1,000 0,04906833 0,09285355 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 1,000 0,04906833 0,09278168 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 1,000 0,05036441 0,09515874 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 1,000 0,05036441 0,09508521 ! developmental maturation GO:0021700 128 69 1,000 0,05036441 0,09501178 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,05085217 0,0958579 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,05085217 0,09578399 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,05085217 0,0957102 ! associative learning GO:0008306 21 10 0,000 0,05085217 0,09563652 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,05085217 0,09556295 ! phosphate transport GO:0006817 24 10 0,000 0,05085217 0,0954895 ! cell volume homeostasis GO:0006884 17 10 0,000 0,05085217 0,09541616 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,05085217 0,09534293 ! CTP metabolic process GO:0046036 11 10 0,000 0,05085217 0,09526982 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 0,05085217 0,09519681 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,05085217 0,09512392 ! GTP metabolic process GO:0046039 11 10 0,000 0,05085217 0,09505114 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,05085217 0,09497847 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,05085217 0,09490591 ! social behavior GO:0035176 29 10 0,000 0,05085217 0,09483347 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,05085217 0,09476113 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,05085217 0,0946889 ! androgen metabolic process GO:0008209 17 10 0,000 0,05085217 0,09461679 ! phospholipid efflux GO:0033700 19 10 0,000 0,05085217 0,09454478 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,05085217 0,09447288 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,05085217 0,09440109 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,05085217 0,09432942 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,05085217 0,09425785 ! pathogenesis GO:0009405 17 10 0,000 0,05085217 0,09418638 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,05085217 0,09411503 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,05085217 0,09404379 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,05085217 0,09397265 ! endoderm development GO:0007492 18 10 0,000 0,05085217 0,09390162 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,05085217 0,0938307 ! arginine catabolic process GO:0006527 17 10 0,000 0,05085217 0,09375988 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,05085217 0,09368917 ! proline metabolic process GO:0006560 13 10 0,000 0,05085217 0,09361857 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,05085217 0,09354807 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 0,05085217 0,09347768 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,05085217 0,0934074 ! V(D)J recombination GO:0033151 34 10 0,000 0,05085217 0,09333722 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,05085217 0,09326715 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,05085217 0,09319718 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,05085217 0,09312732 ! B cell proliferation GO:0042100 19 10 0,000 0,05085217 0,09305756 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,05085217 0,0929879 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,05085217 0,09291835 ! multicellular organism growth GO:0035264 19 10 0,000 0,05085217 0,09284891 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,05085217 0,09277957 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,05085217 0,09271033 ! ruffle organization GO:0031529 17 10 0,000 0,05085217 0,09264119 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,05085217 0,09257216 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,05085217 0,09250323 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,05085217 0,0924344 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,05085217 0,09236568 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,05085217 0,09229706 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 13 10 0,000 0,05085217 0,09222854 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,05085217 0,09216012 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,05085217 0,0920918 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,05085217 0,09202359 ! segment specification GO:0007379 15 10 0,000 0,05085217 0,09195547 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,05085217 0,09188746 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 0,000 0,05085217 0,09181954 ! blastoderm segmentation GO:0007350 19 10 0,000 0,05085217 0,09175173 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,05085217 0,09168401 ! response to dsRNA GO:0043331 23 10 0,000 0,05085217 0,0916164 ! DNA ligation GO:0006266 18 10 0,000 0,05085217 0,09154889 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,05085217 0,09148147 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,05085217 0,09141416 ! melanosome localization GO:0032400 16 10 0,000 0,05085217 0,09134694 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,05085217 0,09127982 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,05085217 0,0912128 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,05085217 0,09114588 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,05085217 0,09107906 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,05085217 0,09101234 ! induction of an organ GO:0001759 17 10 0,000 0,05085217 0,09094571 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,05085217 0,09087918 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,05085217 0,09081275 ! protein sumoylation GO:0016925 17 10 0,000 0,05085217 0,09074641 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,05085217 0,09068018 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,05085217 0,09061403 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,05085217 0,09054799 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,05085217 0,09048204 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,05085217 0,09041619 ! salivary gland development GO:0007431 28 10 0,000 0,05085217 0,09035043 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,05085217 0,09028477 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,05085217 0,0902192 ! midbrain development GO:0030901 14 10 0,000 0,05085217 0,09015373 ! musculoskeletal movement GO:0050881 16 10 0,000 0,05085217 0,09008835 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,05085217 0,09002307 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,05085217 0,08995789 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,05085217 0,08989279 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,05085217 0,08982779 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,05085217 0,08976289 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,05085217 0,08969808 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,05085217 0,08963336 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,05085217 0,08956874 ! detection of calcium ion GO:0005513 24 10 0,000 0,05085217 0,08950421 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,05085217 0,08943977 ! blastocyst formation GO:0001825 18 10 0,000 0,05085217 0,08937542 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,05085217 0,08931117 ! cerebellar cortex development GO:0021695 16 10 0,000 0,05085217 0,08924701 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,05085217 0,08918294 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,05085217 0,08911897 ! response to nicotine GO:0035094 20 10 0,000 0,05085217 0,08905508 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,05085217 0,08899129 ! protein maturation by peptide bond cleavage GO:0051605 118 70 1,000 0,05167277 0,09036261 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 1,000 0,05299324 0,09260549 ! appendage morphogenesis GO:0035107 150 72 1,000 0,05432566 0,09486604 GO:0035108|limb morphogenesis, ! carbohydrate transport GO:0008643 114 72 1,000 0,05432566 0,09479828 ! actin filament organization GO:0007015 167 72 1,000 0,05432566 0,09473061 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 1,000 0,05432566 0,09466304 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 1,000 0,05432566 0,09459557 ! regulation of MAPKKK cascade GO:0043408 157 72 1,000 0,05432566 0,0945282 ! appendage development GO:0048736 151 73 1,000 0,05566988 0,09679823 GO:0060173|limb development, ! humoral immune response GO:0006959 115 73 1,000 0,05566988 0,09672938 ! respiratory burst GO:0045730 17 11 0,000 0,0557937 0,09687562 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,0557937 0,09680682 ! neuron fate specification GO:0048665 18 11 0,000 0,0557937 0,09673811 ! telencephalon cell migration GO:0022029 23 11 0,000 0,0557937 0,0966695 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,0557937 0,09660099 ! thyroid gland development GO:0030878 26 11 0,000 0,0557937 0,09653258 ! synapsis GO:0007129 14 11 0,000 0,0557937 0,09646426 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,0557937 0,09639604 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,0557937 0,09632791 ! response to pain GO:0048265 27 11 0,000 0,0557937 0,09625989 ! keratinocyte proliferation GO:0043616 19 11 0,000 0,0557937 0,09619195 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 0,000 0,0557937 0,09612412 GO:0010812|negative regulation of cell-substrate adhesion, ! bone resorption GO:0045453 16 11 0,000 0,0557937 0,09605638 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,0557937 0,09598873 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,0557937 0,09592118 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,0557937 0,09585373 ! melanocyte differentiation GO:0030318 20 11 0,000 0,0557937 0,09578637 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,0557937 0,0957191 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,0557937 0,09565193 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,0557937 0,09558485 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,0557937 0,09551787 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,0557937 0,09545098 ! UV protection GO:0009650 20 11 0,000 0,0557937 0,09538418 ! adult heart development GO:0007512 16 11 0,000 0,0557937 0,09531748 ! chondrocyte differentiation GO:0002062 27 11 0,000 0,0557937 0,09525087 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,0557937 0,09518436 ! macroautophagy GO:0016236 19 11 0,000 0,0557937 0,09511793 ! temperature homeostasis GO:0001659 18 11 0,000 0,0557937 0,0950516 ! behavioral fear response GO:0001662 27 11 0,000 0,0557937 0,09498537 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,0557937 0,09491922 ! negative regulation of ossification GO:0030279 27 11 0,000 0,0557937 0,09485317 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,0557937 0,0947872 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 0,0557937 0,09472133 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,0557937 0,09465556 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,0557937 0,09458987 ! regulation of organ growth GO:0046620 14 11 0,000 0,0557937 0,09452427 ! pigment granule localization GO:0051875 20 11 0,000 0,0557937 0,09445877 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,0557937 0,09439335 ! vasoconstriction GO:0042310 20 11 0,000 0,0557937 0,09432803 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,0557937 0,09426279 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,0557937 0,09419765 ! embryonic axis specification GO:0000578 19 11 0,000 0,0557937 0,0941326 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,0557937 0,09406763 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,0557937 0,09400276 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,0557937 0,09393797 ! DNA methylation GO:0006306 19 11 0,000 0,0557937 0,09387328 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,0557937 0,09380867 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,0557937 0,09374415 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,0557937 0,09367972 ! prophase GO:0051324 17 11 0,000 0,0557937 0,09361538 ! neuroblast proliferation GO:0007405 25 11 0,000 0,0557937 0,09355113 ! nucleosome positioning GO:0016584 15 11 0,000 0,0557937 0,09348697 ! regulation of isotype switching GO:0045191 24 11 0,000 0,0557937 0,09342289 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,0557937 0,0933589 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,0557937 0,093295 ! apical protein localization GO:0045176 18 11 0,000 0,0557937 0,09323119 ! acid secretion GO:0046717 20 11 0,000 0,0557937 0,09316746 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,0557937 0,09310382 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,0557937 0,09304027 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,0557937 0,09297681 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,0557937 0,09291343 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,0557937 0,09285014 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 0,0557937 0,09278693 ! cholesterol efflux GO:0033344 21 11 0,000 0,0557937 0,09272381 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,0557937 0,09266077 ! oocyte development GO:0048599 20 11 0,000 0,0557937 0,09259783 ! negative regulation of glucose import GO:0046325 18 11 0,000 0,0557937 0,09253496 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 26 11 0,000 0,0557937 0,09247218 ! embryonic gut development GO:0048566 19 11 0,000 0,0557937 0,09240949 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,0557937 0,09234688 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,0557937 0,09228436 ! activation of innate immune response GO:0002218 16 11 0,000 0,0557937 0,09222192 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,0557937 0,09215957 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,0557937 0,0920973 ! lysogeny GO:0030069 22 11 0,000 0,0557937 0,09203511 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,0557937 0,09197301 ! sequestering of metal ion GO:0051238 15 11 0,000 0,0557937 0,09191099 ! nucleus localization GO:0051647 22 11 0,000 0,0557937 0,09184906 ! amino acid transport GO:0006865 148 74 1,000 0,05702574 0,09381406 ! organelle localization GO:0051640 155 74 1,000 0,05702574 0,09375093 ! regulation of transcription factor activity GO:0051090 137 75 1,000 0,05839308 0,09593429 GO:0090046|regulation of transcription regulator activity, ! phosphoinositide-mediated signaling GO:0048015 141 75 1,000 0,05839308 0,09586982 ! leukocyte mediated immunity GO:0002443 136 75 1,000 0,05839308 0,09580543 ! cell-matrix adhesion GO:0007160 181 76 1,000 0,05977175 0,09800159 ! lymphocyte differentiation GO:0030098 193 76 1,000 0,05977175 0,09793586 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,06070964 0,09940593 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,06070964 0,09933935 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,06070964 0,09927286 ! mating GO:0007618 17 12 0,000 0,06070964 0,09920645 ! protein complex disassembly GO:0043241 28 12 0,000 0,06070964 0,09914014 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,06070964 0,09907391 ! regulation of cell projection assembly GO:0060491 33 12 0,000 0,06070964 0,09900777 ! hippocampus development GO:0021766 29 12 0,000 0,06070964 0,09894173 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 0,000 0,06070964 0,09887576 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,06070964 0,09880989 ! T cell proliferation GO:0042098 32 12 0,000 0,06070964 0,09874411 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,06070964 0,09867841 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,06070964 0,0986128 ! ventral spinal cord development GO:0021517 25 12 0,000 0,06070964 0,09854727 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,06070964 0,09848184 ! drug transport GO:0015893 16 12 0,000 0,06070964 0,09841649 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,06070964 0,09835122 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,06070964 0,09828605 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,06070964 0,09822096 ! polyamine metabolic process GO:0006595 18 12 0,000 0,06070964 0,09815595 ! mitotic spindle organization GO:0007052 23 12 0,000 0,06070964 0,09809104 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,06070964 0,0980262 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,06070964 0,09796146 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,06070964 0,0978968 ! lipid digestion GO:0044241 21 12 0,000 0,06070964 0,09783222 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,06070964 0,09776773 ! entry into host cell GO:0030260 34 12 0,000 0,06070964 0,09770332 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,06070964 0,097639 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,06070964 0,09757477 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,06070964 0,09751062 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,06070964 0,09744655 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,06070964 0,09738256 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,06070964 0,09731867 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,06070964 0,09725485 ! snRNA metabolic process GO:0016073 30 12 0,000 0,06070964 0,09719112 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,06070964 0,09712747 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,06070964 0,0970639 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,06070964 0,09700042 ! cranial nerve development GO:0021545 23 12 0,000 0,06070964 0,09693702 ! fucose catabolic process GO:0019317 25 12 0,000 0,06070964 0,09687371 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,06070964 0,09681047 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,06070964 0,09674732 ! autonomic nervous system development GO:0048483 24 12 0,000 0,06070964 0,09668425 ! zymogen activation GO:0031638 18 12 0,000 0,06070964 0,09662127 ! T cell homeostasis GO:0043029 28 12 0,000 0,06070964 0,09655836 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,06070964 0,09649554 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,06070964 0,0964328 ! oocyte differentiation GO:0009994 21 12 0,000 0,06070964 0,09637014 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,06070964 0,09630756 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,06070964 0,09624507 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,06070964 0,09618265 ! defense response to fungus GO:0050832 15 12 0,000 0,06070964 0,09612031 ! developmental induction GO:0031128 22 12 0,000 0,06070964 0,09605806 GO:0045168|cell-cell signaling involved in cell fate specification, ! lamellipodium assembly GO:0030032 24 12 0,000 0,06070964 0,09599589 ! response to cold GO:0009409 17 12 0,000 0,06070964 0,09593379 ! establishment of cell polarity GO:0030010 21 12 0,000 0,06070964 0,09587178 ! regulation of synapse organization GO:0050807 18 12 0,000 0,06070964 0,09580985 ! neurotransmitter transport GO:0006836 142 77 1,000 0,06116159 0,09646079 ! phosphoinositide metabolic process GO:0030384 146 77 1,000 0,06116159 0,09639855 ! positive regulation of ligase activity GO:0051351 130 77 1,000 0,06116159 0,0963364 ! positive regulation of lymphocyte activation GO:0051251 142 78 1,000 0,06256245 0,09847942 ! blood coagulation GO:0007596 151 79 1,000 0,06397419 0,10063679 GO:0050817|coagulation, ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 1,000 0,06397419 0,10057203 ! activation of protein kinase activity GO:0032147 170 80 1,000 0,06539664 0,10274212 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,06560012 0,10299557 ! cGMP metabolic process GO:0046068 18 13 0,000 0,06560012 0,10292942 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,06560012 0,10286335 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,06560012 0,10279737 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,06560012 0,10273147 ! peroxisomal transport GO:0043574 28 13 0,000 0,06560012 0,10266566 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,06560012 0,10259994 ! cartilage condensation GO:0001502 22 13 0,000 0,06560012 0,10253429 ! organelle fusion GO:0048284 36 13 0,000 0,06560012 0,10246873 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,06560012 0,10240326 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,06560012 0,10233787 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,06560012 0,10227256 ! positive regulation of cell growth GO:0030307 24 13 0,000 0,06560012 0,10220733 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,06560012 0,10214219 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,06560012 0,10207713 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,06560012 0,10201216 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,06560012 0,10194727 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,06560012 0,10188245 ! methionine metabolic process GO:0006555 31 13 0,000 0,06560012 0,10181773 ! plasma membrane organization GO:0007009 27 13 0,000 0,06560012 0,10175308 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,06560012 0,10168852 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,06560012 0,10162403 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,06560012 0,10155963 ! cytokine metabolic process GO:0042107 24 13 0,000 0,06560012 0,10149531 ! cellular carbohydrate catabolic process GO:0044275 17 13 0,000 0,06560012 0,10143108 ! exocrine system development GO:0035272 34 13 0,000 0,06560012 0,10136692 ! asymmetric protein localization GO:0008105 24 13 0,000 0,06560012 0,10130285 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,06560012 0,10123885 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 0,06560012 0,10117494 ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,06560012 0,1011111 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,06560012 0,10104735 ! protein homotetramerization GO:0051289 24 13 0,000 0,06560012 0,10098368 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,06560012 0,10092009 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,06560012 0,10085658 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,06560012 0,10079315 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,06560012 0,10072979 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,06560012 0,10066652 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,06560012 0,10060333 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,06560012 0,10054021 ! histone methylation GO:0016571 29 13 0,000 0,06560012 0,10047718 ! chromatin silencing GO:0006342 29 13 0,000 0,06560012 0,10041422 ! gland morphogenesis GO:0022612 31 13 0,000 0,06560012 0,10035135 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,06560012 0,10028855 ! regulation of epidermis development GO:0045682 19 13 0,000 0,06560012 0,10022583 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,06560012 0,10016319 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,06560012 0,10010063 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,06560012 0,10003814 ! spleen development GO:0048536 24 13 0,000 0,06560012 0,09997573 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,06560012 0,0999134 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,06560012 0,09985115 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,06560012 0,09978898 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,06560012 0,09972688 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,06560012 0,09966486 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,06560012 0,09960292 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,06560012 0,09954106 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,06560012 0,09947927 ! insulin secretion GO:0030073 24 13 0,000 0,06560012 0,09941756 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,06560012 0,09935592 ! acrosome reaction GO:0007340 19 13 0,000 0,06560012 0,09929436 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,06560012 0,09923288 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,06560012 0,09917147 ! positive regulation of phosphorylation GO:0042327 149 81 1,000 0,06682967 0,10096777 ! protein import into nucleus GO:0006606 174 82 1,000 0,06827312 0,10308482 ! response to drug GO:0042493 149 83 1,000 0,06972686 0,10521477 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 1,000 0,06972686 0,10514982 GO:0045937|positive regulation of phosphate metabolic process, ! nuclear import GO:0051170 177 83 1,000 0,06972686 0,10508496 ! rRNA transcription GO:0009303 28 14 0,000 0,07046528 0,10613236 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,07046528 0,10606697 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 0,07046528 0,10600165 ! water transport GO:0006833 21 14 0,000 0,07046528 0,10593642 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,07046528 0,10587127 ! non-recombinational repair GO:0000726 29 14 0,000 0,07046528 0,1058062 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,07046528 0,10574121 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,07046528 0,1056763 ! hair follicle morphogenesis GO:0031069 27 14 0,000 0,07046528 0,10561146 ! RNA polyadenylation GO:0043631 32 14 0,000 0,07046528 0,10554671 ! lipid localization GO:0010876 32 14 0,000 0,07046528 0,10548204 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 0,07046528 0,10541744 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 0,000 0,07046528 0,10535293 ! regulated secretory pathway GO:0045055 24 14 0,000 0,07046528 0,10528849 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,07046528 0,10522414 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,07046528 0,10515986 ! arginine metabolic process GO:0006525 21 14 0,000 0,07046528 0,10509566 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,07046528 0,10503153 ! regulation of heart rate GO:0002027 25 14 0,000 0,07046528 0,10496749 ! fear response GO:0042596 34 14 0,000 0,07046528 0,10490353 ! organic alcohol transport GO:0015850 29 14 0,000 0,07046528 0,10483964 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,07046528 0,10477583 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 0,000 0,07046528 0,1047121 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,07046528 0,10464844 ! neutral amino acid transport GO:0015804 28 14 0,000 0,07046528 0,10458486 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,07046528 0,10452136 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,07046528 0,10445794 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,07046528 0,10439459 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,07046528 0,10433132 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,07046528 0,10426813 ! ribosome assembly GO:0042255 18 14 0,000 0,07046528 0,10420502 ! cerebellum development GO:0021549 23 14 0,000 0,07046528 0,10414198 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,07046528 0,10407901 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,07046528 0,10401612 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,07046528 0,10395331 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,07046528 0,10389058 ! NADP metabolic process GO:0006739 24 14 0,000 0,07046528 0,10382792 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,07046528 0,10376533 ! oxygen transport GO:0015671 22 14 0,000 0,07046528 0,10370282 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,07046528 0,10364039 ! male genitalia development GO:0030539 26 14 0,000 0,07046528 0,10357803 ! regulation of axon extension GO:0030516 43 14 0,000 0,07046528 0,10351575 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,07046528 0,10345354 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 0,07046528 0,1033914 ! T cell activation GO:0042110 189 84 1,000 0,07119073 0,10439312 ! response to nutrient GO:0007584 135 84 1,000 0,07119073 0,1043305 ! digestion GO:0007586 130 84 1,000 0,07119073 0,10426795 ! regulation of ligase activity GO:0051340 147 84 1,000 0,07119073 0,10420548 ! hemostasis GO:0007599 165 85 1,000 0,07266459 0,10629915 ! regulation of neuron differentiation GO:0045664 187 85 1,000 0,07266459 0,10623554 ! positive regulation of cell activation GO:0050867 161 86 1,000 0,07414829 0,10833988 GO:0002696|positive regulation of leukocyte activation, ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,07530525 0,10996457 ! lactation GO:0007595 30 15 0,000 0,07530525 0,10989888 ! reproductive cellular process GO:0048610 22 15 0,000 0,07530525 0,10983326 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,07530525 0,10976773 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,07530525 0,10970228 ! superoxide anion generation GO:0042554 22 15 0,000 0,07530525 0,1096369 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,07530525 0,1095716 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,07530525 0,10950638 ! copper ion transport GO:0006825 22 15 0,000 0,07530525 0,10944124 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,07530525 0,10937617 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,07530525 0,10931118 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,07530525 0,10924627 ! sulfate transport GO:0008272 27 15 0,000 0,07530525 0,10918143 ! response to cAMP GO:0051591 25 15 0,000 0,07530525 0,10911668 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,07530525 0,109052 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,07530525 0,10898739 ! response to hexose stimulus GO:0009746 25 15 0,000 0,07530525 0,10892286 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,07530525 0,10885841 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,07530525 0,10879404 ! vesicle coating GO:0006901 38 15 0,000 0,07530525 0,10872974 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 0,07530525 0,10866552 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 0,07530525 0,10860137 ! regulation of exocytosis GO:0017157 26 15 0,000 0,07530525 0,1085373 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,07530525 0,1084733 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,07530525 0,10840938 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,07530525 0,10834553 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,07530525 0,10828176 ! regulation of vasodilation GO:0042312 27 15 0,000 0,07530525 0,10821807 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,07530525 0,10815445 ! histone deacetylation GO:0016575 24 15 0,000 0,07530525 0,1080909 ! water homeostasis GO:0030104 28 15 0,000 0,07530525 0,10802743 ! cofactor transport GO:0051181 30 15 0,000 0,07530525 0,10796404 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,07530525 0,10790071 ! intestinal absorption GO:0050892 31 15 0,000 0,07530525 0,10783747 ! dopamine metabolic process GO:0042417 35 15 0,000 0,07530525 0,10777429 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,07530525 0,10771119 ! heme biosynthetic process GO:0006783 33 15 0,000 0,07530525 0,10764817 ! cell killing GO:0001906 32 15 0,000 0,07530525 0,10758521 ! lymphocyte homeostasis GO:0002260 33 15 0,000 0,07530525 0,10752234 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,07530525 0,10745953 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,07530525 0,1073968 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,07530525 0,10733414 ! actin filament polymerization GO:0030041 27 15 0,000 0,07530525 0,10727156 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,07530525 0,10720904 ! nucleosome assembly GO:0006334 126 87 1,000 0,07564171 0,10762534 ! chromatin assembly GO:0031497 128 88 1,000 0,0771447 0,10969994 ! one-carbon metabolic process GO:0006730 167 88 1,000 0,0771447 0,10963612 ! protein localization in nucleus GO:0034504 192 89 1,000 0,07865711 0,11172053 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,08012015 0,11373243 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,08012015 0,11366638 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,08012015 0,11360041 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,08012015 0,11353452 ! bone remodeling GO:0046849 28 16 0,000 0,08012015 0,1134687 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,08012015 0,11340296 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,08012015 0,1133373 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,08012015 0,11327171 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,08012015 0,1132062 ! startle response GO:0001964 28 16 0,000 0,08012015 0,11314076 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,08012015 0,1130754 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,08012015 0,11301011 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,08012015 0,1129449 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,08012015 0,11287977 ! protein polyubiquitination GO:0000209 41 16 0,000 0,08012015 0,11281471 ! glutamate metabolic process GO:0006536 25 16 0,000 0,08012015 0,11274972 ! pituitary gland development GO:0021983 30 16 0,000 0,08012015 0,11268481 ! response to osmotic stress GO:0006970 27 16 0,000 0,08012015 0,11261997 ! lysosomal transport GO:0007041 31 16 0,000 0,08012015 0,11255521 ! fructose metabolic process GO:0006000 25 16 0,000 0,08012015 0,11249053 ! stem cell development GO:0048864 46 16 0,000 0,08012015 0,11242591 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,08012015 0,11236137 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,08012015 0,11229691 ! intermediate filament-based process GO:0045103 36 16 0,000 0,08012015 0,11223252 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,08012015 0,1121682 ! negative regulation of immune response GO:0050777 38 16 0,000 0,08012015 0,11210396 ! axon cargo transport GO:0008088 46 16 0,000 0,08012015 0,11203979 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,08012015 0,11197569 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,08012015 0,11191167 ! positive regulation of protein import into nucleus GO:0042307 34 16 0,000 0,08012015 0,11184772 ! mRNA splice site selection GO:0006376 44 16 0,000 0,08012015 0,11178385 ! tissue regeneration GO:0042246 27 16 0,000 0,08012015 0,11172004 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,08012015 0,11165631 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,08012015 0,11159265 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,08012015 0,11152907 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,08012015 0,11146555 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,08012015 0,11140211 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,08012015 0,11133875 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,08012015 0,11127545 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,08012015 0,11121222 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,08012015 0,11114907 ! peptide hormone processing GO:0016486 27 16 0,000 0,08012015 0,11108599 ! protein-DNA complex assembly GO:0065004 134 92 1,000 0,08324955 0,11535942 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 1,000 0,08479832 0,11743894 GO:0010498|proteasomal protein catabolic process, ! amine transport GO:0015837 181 93 1,000 0,08479832 0,11737241 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,08491011 0,11746058 ! metencephalon development GO:0022037 32 17 0,000 0,08491011 0,11739411 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,08491011 0,11732771 ! signal complex assembly GO:0007172 47 17 0,000 0,08491011 0,11726139 ! filopodium assembly GO:0046847 42 17 0,000 0,08491011 0,11719514 ! endothelial cell migration GO:0043542 31 17 0,000 0,08491011 0,11712896 ! gene silencing by RNA GO:0031047 38 17 0,000 0,08491011 0,11706286 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,08491011 0,11699684 ! glial cell development GO:0021782 28 17 0,000 0,08491011 0,11693089 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,08491011 0,11686501 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,08491011 0,11679921 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,08491011 0,11673348 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 0,000 0,08491011 0,11666782 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,08491011 0,11660224 ! myoblast differentiation GO:0045445 50 17 0,000 0,08491011 0,11653674 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,08491011 0,1164713 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,08491011 0,11640594 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,08491011 0,11634066 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,08491011 0,11627544 ! NAD metabolic process GO:0019674 33 17 0,000 0,08491011 0,1162103 ! membrane budding GO:0006900 42 17 0,000 0,08491011 0,11614524 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,08491011 0,11608024 ! regulation of protein binding GO:0043393 33 17 0,000 0,08491011 0,11601532 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,08491011 0,11595047 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,08491011 0,11588569 ! genitalia development GO:0048806 32 17 0,000 0,08491011 0,11582099 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,08491011 0,11575636 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,08491011 0,1156918 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,08491011 0,11562731 ! neutrophil chemotaxis GO:0030593 29 17 0,000 0,08491011 0,11556289 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,08491011 0,11549855 ! steroid catabolic process GO:0006706 34 17 0,000 0,08491011 0,11543427 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,08491011 0,11537007 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,08491011 0,11530594 ! gas transport GO:0015669 26 17 0,000 0,08491011 0,11524188 ! organic cation transport GO:0015695 32 17 0,000 0,08491011 0,1151779 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,08491011 0,11511398 ! regulation of membrane potential GO:0042391 179 94 1,000 0,08635584 0,11700905 ! nucleosome organization GO:0034728 143 95 1,000 0,08792198 0,11906507 ! negative regulation of multicellular organismal process GO:0051241 174 95 1,000 0,08792198 0,11899911 ! sex differentiation GO:0007548 171 96 1,000 0,08949661 0,12106324 ! regulation of T cell activation GO:0050863 175 96 1,000 0,08949661 0,12099624 ! positive regulation of protein complex assembly GO:0031334 34 18 0,000 0,08967526 0,12117072 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,08967526 0,12110374 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,08967526 0,12103683 ! limbic system development GO:0021761 40 18 0,000 0,08967526 0,12097 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,08967526 0,12090324 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,08967526 0,12083655 ! adult walking behavior GO:0007628 36 18 0,000 0,08967526 0,12076994 ! patterning of blood vessels GO:0001569 43 18 0,000 0,08967526 0,1207034 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,08967526 0,12063693 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,08967526 0,12057054 ! centrosome cycle GO:0007098 26 18 0,000 0,08967526 0,12050422 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,08967526 0,12043797 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,08967526 0,12037179 ! epidermis morphogenesis GO:0048730 43 18 0,000 0,08967526 0,12030569 ! glycine metabolic process GO:0006544 30 18 0,000 0,08967526 0,12023966 ! glutamine metabolic process GO:0006541 29 18 0,000 0,08967526 0,1201737 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,08967526 0,12010782 ! DNA integration GO:0015074 32 18 0,000 0,08967526 0,12004201 ! negative regulation of protein catabolic process GO:0042177 42 18 0,000 0,08967526 0,11997627 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,08967526 0,1199106 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,08967526 0,119845 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,08967526 0,11977948 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,08967526 0,11971402 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,08967526 0,11964864 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,08967526 0,11958333 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,08967526 0,11951809 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,08967526 0,11945292 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,08967526 0,11938783 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,08967526 0,1193228 ! detection of bacterium GO:0016045 22 18 0,000 0,08967526 0,11925785 ! nerve development GO:0021675 34 18 0,000 0,08967526 0,11919296 ! defense response to virus GO:0051607 43 18 0,000 0,08967526 0,11912815 ! microspike assembly GO:0030035 46 18 0,000 0,08967526 0,1190634 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,08967526 0,11899873 ! transcription initiation GO:0006352 171 97 1,000 0,0910796 0,12079666 ! leukocyte differentiation GO:0002521 232 98 1,000 0,09267082 0,12284038 ! forebrain development GO:0030900 210 98 1,000 0,09267082 0,12277376 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,09441574 0,12501769 ! negative regulation of defense response GO:0031348 27 19 0,000 0,09441574 0,12494997 ! neuron maturation GO:0042551 46 19 0,000 0,09441574 0,12488232 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,09441574 0,12481474 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 0,09441574 0,12474724 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,09441574 0,12467981 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,09441574 0,12461245 ! inositol metabolic process GO:0006020 33 19 0,000 0,09441574 0,12454516 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,09441574 0,12447795 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,09441574 0,12441081 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,09441574 0,12434374 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,09441574 0,12427675 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,09441574 0,12420982 ! cerebral cortex development GO:0021987 40 19 0,000 0,09441574 0,12414297 ! pigmentation during development GO:0048066 42 19 0,000 0,09441574 0,12407619 ! heme metabolic process GO:0042168 40 19 0,000 0,09441574 0,12400948 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,09441574 0,12394285 ! response to fungus GO:0009620 26 19 0,000 0,09441574 0,12387628 ! protein export from nucleus GO:0006611 40 19 0,000 0,09441574 0,12380979 ! heart process GO:0003015 32 19 0,000 0,09441574 0,12374337 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,09441574 0,12367702 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,09441574 0,12361074 ! visual learning GO:0008542 38 19 0,000 0,09441574 0,12354453 ! cellular pigmentation GO:0033059 37 19 0,000 0,09441574 0,12347839 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,09441574 0,12341233 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,09441574 0,12334633 ! vitamin transport GO:0051180 31 19 0,000 0,09441574 0,12328041 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,09441574 0,12321455 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,09441574 0,12314877 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,09441574 0,12308305 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,09441574 0,12301741 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,09441574 0,12295183 ! cilium assembly GO:0042384 38 19 0,000 0,09441574 0,12288633 ! peptide hormone secretion GO:0030072 32 19 0,000 0,09441574 0,1228209 ! protein secretion GO:0009306 45 20 0,000 0,09913166 0,12888698 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,09913166 0,12881842 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,09913166 0,12874994 ! positive regulation of ossification GO:0045778 50 20 0,000 0,09913166 0,12868153 ! skin development GO:0043588 42 20 0,000 0,09913166 0,12861319 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,09913166 0,12854492 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,09913166 0,12847673 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,09913166 0,12840861 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,09913166 0,12834056 ! bile acid metabolic process GO:0008206 34 20 0,000 0,09913166 0,12827258 ! retinoid metabolic process GO:0001523 34 20 0,000 0,09913166 0,12820468 GO:0016101|diterpenoid metabolic process, ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,09913166 0,12813684 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,09913166 0,12806908 GO:0032392|DNA geometric change, ! cellular response to unfolded protein GO:0034620 35 20 0,000 0,09913166 0,12800139 GO:0030968|endoplasmic reticulum unfolded protein response, ! body fluid secretion GO:0007589 33 20 0,000 0,09913166 0,12793377 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,09913166 0,12786623 ! peptide secretion GO:0002790 38 20 0,000 0,09913166 0,12779875 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,09913166 0,12773135 ! regulation of fatty acid metabolic process GO:0019217 45 20 0,000 0,09913166 0,12766401 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,09913166 0,12759675 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,09913166 0,12752956 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,09913166 0,12746244 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,09913166 0,12739539 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,09913166 0,12732841 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,09913166 0,1272615 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,09913166 0,12719466 ! regulation of glucose import GO:0046324 30 20 0,000 0,09913166 0,12712789 GO:0010827|regulation of glucose transport, ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,09913166 0,12706119 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,09913166 0,12699457 ! negative regulation of translation GO:0017148 32 20 0,000 0,09913166 0,12692801 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,09913166 0,12686152 ! regulation of cell killing GO:0031341 46 21 0,000 0,10382315 0,13279579 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,10382315 0,1327263 ! hormone secretion GO:0046879 39 21 0,000 0,10382315 0,13265688 ! cAMP metabolic process GO:0046058 41 21 0,000 0,10382315 0,13258754 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,10382315 0,13251826 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,10382315 0,13244906 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,10382315 0,13237994 ! ovarian follicle development GO:0001541 39 21 0,000 0,10382315 0,13231088 ! smooth muscle contraction GO:0006939 48 21 0,000 0,10382315 0,1322419 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,10382315 0,13217298 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,10382315 0,13210414 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,10382315 0,13203538 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,10382315 0,13196668 GO:0006692|prostanoid metabolic process, ! regulation of vasoconstriction GO:0019229 40 21 0,000 0,10382315 0,13189805 ! sensory perception of pain GO:0019233 33 21 0,000 0,10382315 0,1318295 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,10382315 0,13176102 ! diencephalon development GO:0021536 36 21 0,000 0,10382315 0,1316926 ! collagen fibril organization GO:0030199 62 21 0,000 0,10382315 0,13162426 ! positive regulation of inflammatory response GO:0050729 41 21 0,000 0,10382315 0,13155599 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,10382315 0,13148779 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 0,10382315 0,13141967 ! collagen catabolic process GO:0030574 29 21 0,000 0,10382315 0,13135161 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,10382315 0,13128362 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,10382315 0,1312157 ! sperm-egg recognition GO:0035036 23 21 0,000 0,10382315 0,13114786 ! actin filament-based movement GO:0030048 47 21 0,000 0,10382315 0,13108008 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,10849034 0,13690181 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,10849034 0,13683114 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,10849034 0,13676053 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,10849034 0,13669 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,10849034 0,13661954 ! microtubule-based transport GO:0010970 59 22 0,000 0,10849034 0,13654916 ! inactivation of MAPK activity GO:0000188 45 22 0,000 0,10849034 0,13647884 ! vacuolar transport GO:0007034 41 22 0,000 0,10849034 0,1364086 ! central nervous system neuron development GO:0021954 47 22 0,000 0,10849034 0,13633843 ! fucose metabolic process GO:0006004 44 22 0,000 0,10849034 0,13626833 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,10849034 0,13619831 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,10849034 0,13612836 ! ureteric bud development GO:0001657 50 22 0,000 0,10849034 0,13605848 ! stem cell differentiation GO:0048863 57 22 0,000 0,10849034 0,13598867 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,10849034 0,13591893 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 0,10849034 0,13584926 ! renal system process GO:0003014 42 22 0,000 0,10849034 0,13577967 ! vasodilation GO:0042311 40 22 0,000 0,10849034 0,13571014 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,10849034 0,13564069 ! detection of chemical stimulus GO:0009593 42 22 0,000 0,10849034 0,13557131 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,10849034 0,135502 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,10849034 0,13543276 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,10849034 0,13536359 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,10849034 0,13529449 ! sarcomere organization GO:0045214 32 22 0,000 0,10849034 0,13522546 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,10849034 0,13515651 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,10849034 0,13508762 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,10849034 0,1350188 ! gut development GO:0048565 44 22 0,000 0,10849034 0,13495006 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,10849034 0,13488138 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,10849034 0,13481277 ! protein stabilization GO:0050821 41 22 0,000 0,10849034 0,13474424 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,11313336 0,14043943 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,11313336 0,14036811 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,11313336 0,14029685 ! gluconeogenesis GO:0006094 38 23 0,000 0,11313336 0,14022567 ! glycerol metabolic process GO:0006071 40 23 0,000 0,11313336 0,14015457 ! viral genome replication GO:0019079 44 23 0,000 0,11313336 0,14008353 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,11313336 0,14001257 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,11313336 0,13994167 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,11313336 0,13987085 ! regeneration GO:0031099 42 23 0,000 0,11313336 0,1398001 ! visual behavior GO:0007632 46 23 0,000 0,11313336 0,13972943 ! regulation of DNA recombination GO:0000018 51 23 0,000 0,11313336 0,13965882 ! response to ethanol GO:0045471 47 23 0,000 0,11313336 0,13958828 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,11313336 0,13951782 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,11313336 0,13944743 ! peroxisome organization GO:0007031 43 23 0,000 0,11313336 0,13937711 ! lysosome organization GO:0007040 47 23 0,000 0,11313336 0,13930686 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 0,11313336 0,13923668 ! vesicle targeting GO:0006903 49 23 0,000 0,11313336 0,13916657 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,11313336 0,13909653 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,11313336 0,13902656 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,11313336 0,13895666 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,11313336 0,13888684 ! DNA modification GO:0006304 36 23 0,000 0,11313336 0,13881708 ! fatty acid transport GO:0015908 47 23 0,000 0,11313336 0,13874739 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,11313336 0,13867777 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,11313336 0,13860823 ! hormone transport GO:0009914 41 23 0,000 0,11313336 0,13853875 ! cell-cell recognition GO:0009988 28 23 0,000 0,11313336 0,13846934 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,11313336 0,1384 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,11313336 0,13833073 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,11313336 0,13826153 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,11775233 0,14383447 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,11775233 0,14376259 GO:0016444|somatic cell DNA recombination, ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,11775233 0,14369078 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,11775233 0,14361904 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,11775233 0,14354738 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,11775233 0,14347578 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 0,11775233 0,14340426 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,11775233 0,14333281 ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,11775233 0,14326142 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,11775233 0,14319011 GO:0042278|purine nucleoside metabolic process, ! positive regulation of cytoskeleton organization GO:0051495 52 24 0,000 0,11775233 0,14311888 ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,11775233 0,14304771 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,11775233 0,14297661 GO:0051693|actin filament capping, ! regulation of viral reproduction GO:0050792 41 24 0,000 0,11775233 0,14290558 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,11775233 0,14283463 GO:0002708|positive regulation of lymphocyte mediated immunity, ! leukotriene metabolic process GO:0006691 47 24 0,000 0,11775233 0,14276374 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,11775233 0,14269293 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,11775233 0,14262218 ! membrane depolarization GO:0051899 45 24 0,000 0,11775233 0,14255151 ! pallium development GO:0021543 56 24 0,000 0,11775233 0,1424809 ! oogenesis GO:0048477 44 24 0,000 0,11775233 0,14241037 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,11775233 0,1423399 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,11775233 0,14226951 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,11775233 0,14219918 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,11775233 0,14212892 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,11775233 0,14205874 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,11775233 0,14198862 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,11775233 0,14191857 ! negative regulation of catabolic process GO:0009895 52 24 0,000 0,11775233 0,14184859 ! regulation of amine transport GO:0051952 41 24 0,000 0,11775233 0,14177868 ! myeloid leukocyte differentiation GO:0002573 46 25 0,000 0,12234737 0,14723873 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,12234737 0,14716623 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,12234737 0,14709381 ! phototransduction GO:0007602 37 25 0,000 0,12234737 0,14702146 ! keratinization GO:0031424 37 25 0,000 0,12234737 0,14694918 ! vacuole organization GO:0007033 49 25 0,000 0,12234737 0,14687696 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,12234737 0,14680482 ! receptor metabolic process GO:0043112 53 25 0,000 0,12234737 0,14673276 ! chromosome condensation GO:0030261 48 25 0,000 0,12234737 0,14666076 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,12234737 0,14658883 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,12234737 0,14651697 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,12234737 0,14644518 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,12234737 0,14637347 ! immunoglobulin production GO:0002377 62 25 0,000 0,12234737 0,14630182 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,12234737 0,14623025 ! leukocyte homeostasis GO:0001776 50 25 0,000 0,12234737 0,14615874 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,12234737 0,1460873 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,12691861 0,1514715 ! initiation of viral infection GO:0019059 60 26 0,000 0,12691861 0,15139754 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,12691861 0,15132365 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,12691861 0,15124983 ! molting cycle process GO:0022404 52 26 0,000 0,12691861 0,15117609 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,12691861 0,15110241 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,12691861 0,15102881 GO:0006479|protein amino acid methylation, ! microtubule organizing center organization GO:0031023 42 26 0,000 0,12691861 0,15095528 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,12691861 0,15088183 ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,12691861 0,15080844 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,12691861 0,15073513 ! digestive system process GO:0022600 49 26 0,000 0,12691861 0,15066188 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,12691861 0,15058871 ! regulation of cellular ketone metabolic process GO:0010565 51 26 0,000 0,12691861 0,15051561 ! osteoblast differentiation GO:0001649 63 26 0,000 0,12691861 0,15044258 ! coenzyme catabolic process GO:0009109 42 26 0,000 0,12691861 0,15036962 ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,12691861 0,15029673 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,12691861 0,15022391 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,12691861 0,15015116 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,12691861 0,15007849 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,12691861 0,15000588 ! regulation of blood coagulation GO:0030193 46 26 0,000 0,12691861 0,14993334 ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,12691861 0,14986088 ! blastocyst development GO:0001824 50 26 0,000 0,12691861 0,14978848 ! telomere organization GO:0032200 46 26 0,000 0,12691861 0,14971615 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,12691861 0,1496439 ! alditol metabolic process GO:0019400 44 26 0,000 0,12691861 0,14957171 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,12691861 0,14949959 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,13146616 0,1547816 ! embryonic pattern specification GO:0009880 49 27 0,000 0,13146616 0,15470705 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,13146616 0,15463256 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,13146616 0,15455815 ! positive regulation of cell projection organization GO:0031346 66 27 0,000 0,13146616 0,1544838 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,13146616 0,15440953 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,13146616 0,15433533 ! iron ion transport GO:0006826 65 27 0,000 0,13146616 0,15426121 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,13146616 0,15418715 ! superoxide metabolic process GO:0006801 41 27 0,000 0,13146616 0,15411316 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,13146616 0,15403925 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,13146616 0,1539654 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,13146616 0,15389163 ! leukocyte proliferation GO:0070661 59 27 0,000 0,13146616 0,15381793 GO:0032943|mononuclear cell proliferation, ! neuron fate commitment GO:0048663 52 28 0,000 0,13599016 0,15903492 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,13599016 0,15895883 ! vesicle docking GO:0048278 55 28 0,000 0,13599016 0,15888281 ! negative regulation of protein modification process GO:0031400 66 28 0,000 0,13599016 0,15880686 ! fat cell differentiation GO:0045444 57 28 0,000 0,13599016 0,15873098 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,13599016 0,15865518 ! sperm motility GO:0030317 37 28 0,000 0,13599016 0,15857945 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,13599016 0,15850379 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,13599016 0,15842821 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,13599016 0,15835269 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,13599016 0,15827725 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,13599016 0,15820188 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,13599016 0,15812658 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,13599016 0,15805136 ! glutathione metabolic process GO:0006749 42 28 0,000 0,13599016 0,1579762 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,13599016 0,15790112 ! lipid oxidation GO:0034440 48 28 0,000 0,13599016 0,15782611 GO:0019395|fatty acid oxidation, ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,13599016 0,15775116 ! translational initiation GO:0006413 66 29 0,000 0,14049071 0,16289455 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,14049071 0,16281727 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,14049071 0,16274007 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! autophagy GO:0006914 47 29 0,000 0,14049071 0,16266295 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,14049071 0,16258589 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,14049071 0,16250891 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,14049071 0,162432 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,14049071 0,16235516 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 0,000 0,14049071 0,1622784 ! synaptogenesis GO:0007416 46 29 0,000 0,14049071 0,16220171 ! negative regulation of neuron differentiation GO:0045665 46 29 0,000 0,14049071 0,16212509 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,14049071 0,16204854 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,14049071 0,16197207 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,14049071 0,16189567 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,14496796 0,16697629 ! phenol metabolic process GO:0018958 56 30 0,000 0,14496796 0,1668976 ! negative regulation of protein complex assembly GO:0031333 68 30 0,000 0,14496796 0,16681899 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,14496796 0,16674045 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,14496796 0,16666198 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,14496796 0,16658359 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,14496796 0,16650527 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,14496796 0,16642703 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,14496796 0,16634886 ! myofibril assembly GO:0030239 50 30 0,000 0,14496796 0,16627076 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 72 30 0,000 0,14496796 0,16619273 ! determination of left/right symmetry GO:0007368 53 30 0,000 0,14496796 0,16611478 ! cell fate determination GO:0001709 64 30 0,000 0,14496796 0,1660369 ! positive regulation of multicellular organism growth GO:0040018 55 30 0,000 0,14496796 0,1659591 ! phospholipid transport GO:0015914 65 30 0,000 0,14496796 0,16588137 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,14496796 0,16580371 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,14496796 0,16572612 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,14496796 0,1656486 ! negative regulation of transcription regulator activity GO:0090048 57 30 0,000 0,14496796 0,16557116 GO:0043433|negative regulation of transcription factor activity, ! regulation of coagulation GO:0050818 52 30 0,000 0,14496796 0,16549379 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,149422 0,17049881 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,149422 0,17041921 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,149422 0,17033968 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,149422 0,17026024 ! regulation of innate immune response GO:0045088 57 31 0,000 0,149422 0,17018086 ! ovulation cycle process GO:0022602 55 31 0,000 0,149422 0,17010156 ! peptide transport GO:0015833 60 31 0,000 0,149422 0,17002233 ! male gonad development GO:0008584 56 31 0,000 0,149422 0,16994318 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,149422 0,1698641 ! detection of light stimulus GO:0009583 44 31 0,000 0,149422 0,16978509 ! natural killer cell activation GO:0030101 50 31 0,000 0,149422 0,16970616 ! cofactor catabolic process GO:0051187 54 31 0,000 0,149422 0,1696273 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,149422 0,16954851 ! eye morphogenesis GO:0048592 65 31 0,000 0,149422 0,1694698 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,149422 0,16939116 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,15385297 0,17433339 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,15385297 0,17425257 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,15385297 0,17417182 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,15385297 0,17409115 ! metanephros development GO:0001656 81 32 0,000 0,15385297 0,17401055 ! muscle cell development GO:0055001 52 32 0,000 0,15385297 0,17393003 ! mesoderm formation GO:0001707 73 32 0,000 0,15385297 0,17384958 ! hexose biosynthetic process GO:0019319 53 32 0,000 0,15385297 0,17376921 ! ovulation cycle GO:0042698 57 32 0,000 0,15385297 0,17368891 ! BMP signaling pathway GO:0030509 71 32 0,000 0,15385297 0,17360868 ! hindbrain development GO:0030902 65 32 0,000 0,15385297 0,17352853 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,15385297 0,17344845 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,15385297 0,17336845 ! gene silencing GO:0016458 71 32 0,000 0,15385297 0,17328852 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,15826098 0,17817123 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,15826098 0,17808916 GO:0055092|sterol homeostasis, ! pigment biosynthetic process GO:0046148 73 33 0,000 0,15826098 0,17800716 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,15826098 0,17792525 ! triglyceride metabolic process GO:0006641 46 33 0,000 0,15826098 0,1778434 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,15826098 0,17776164 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,15826098 0,17767995 ! leukocyte chemotaxis GO:0030595 55 33 0,000 0,15826098 0,17759833 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,15826098 0,17751679 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,15826098 0,17743532 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,15826098 0,17735393 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,16264614 0,18218456 ! glial cell differentiation GO:0010001 67 34 0,000 0,16264614 0,18210107 ! post-embryonic development GO:0009791 76 34 0,000 0,16264614 0,18201765 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,16264614 0,18193431 ! cholesterol transport GO:0030301 62 34 0,000 0,16264614 0,18185104 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,16264614 0,18176785 ! spliceosome assembly GO:0000245 75 34 0,000 0,16264614 0,18168474 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,16264614 0,1816017 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,16264614 0,18151874 ! formation of primary germ layer GO:0001704 76 34 0,000 0,16264614 0,18143586 ! cell fate specification GO:0001708 56 34 0,000 0,16264614 0,18135305 ! negative regulation of MAP kinase activity GO:0043407 78 34 0,000 0,16264614 0,18127031 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,16264614 0,18118766 ! adult locomotory behavior GO:0008344 62 34 0,000 0,16264614 0,18110507 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,16700859 0,1858779 ! negative regulation of secretion GO:0051048 68 35 0,000 0,16700859 0,18579325 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,16700859 0,18570869 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,16700859 0,1856242 ! membrane docking GO:0022406 69 35 0,000 0,16700859 0,18553978 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,16700859 0,18545545 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,16700859 0,18537119 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,16700859 0,185287 ! ceramide metabolic process GO:0006672 72 35 0,000 0,16700859 0,1852029 ! telencephalon development GO:0021537 81 35 0,000 0,16700859 0,18511887 ! sterol transport GO:0015918 63 35 0,000 0,16700859 0,18503491 ! vesicle localization GO:0051648 70 35 0,000 0,16700859 0,18495104 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,17134843 0,18967114 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,17134843 0,18958524 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,17134843 0,18949942 ! positive regulation of cell development GO:0010720 85 36 0,000 0,17134843 0,18941367 ! protein targeting to membrane GO:0006612 75 36 0,000 0,17134843 0,189328 ! regulation of proteolysis GO:0030162 77 36 0,000 0,17134843 0,18924241 ! aerobic respiration GO:0009060 56 36 0,000 0,17134843 0,1891569 ! cytokine production GO:0001816 68 36 0,000 0,17134843 0,18907146 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,17134843 0,1889861 ! monosaccharide biosynthetic process GO:0046364 57 36 0,000 0,17134843 0,18890082 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 0,000 0,17566578 0,19357308 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! negative regulation of cell adhesion GO:0007162 94 37 0,000 0,17566578 0,1934858 ! odontogenesis GO:0042476 74 37 0,000 0,17566578 0,19339861 ! actomyosin structure organization GO:0031032 68 37 0,000 0,17566578 0,19331149 ! female gonad development GO:0008585 71 37 0,000 0,17566578 0,19322445 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,17996076 0,19785965 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,17996076 0,19777064 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,17996076 0,19768172 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,17996076 0,19759287 ! neutral lipid metabolic process GO:0006638 54 38 0,000 0,17996076 0,19750411 GO:0006639|acylglycerol metabolic process, ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,17996076 0,19741542 ! regulation of protein stability GO:0031647 77 38 0,000 0,17996076 0,19732681 ! spermatid development GO:0007286 69 38 0,000 0,17996076 0,19723829 ! pigment metabolic process GO:0042440 87 38 0,000 0,17996076 0,19714984 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,18423348 0,20174021 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,18423348 0,20164982 ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,18423348 0,20155952 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,18423348 0,20146929 ! erythrocyte homeostasis GO:0034101 75 39 0,000 0,18423348 0,20137915 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,18423348 0,20128909 ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,18423348 0,20119911 ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,18848406 0,20574914 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,18848406 0,20565724 GO:0046660|female sex differentiation, ! lipid homeostasis GO:0055088 75 40 0,000 0,18848406 0,20556543 ! mismatch repair GO:0006298 58 40 0,000 0,18848406 0,2054737 ! glycerol ether metabolic process GO:0006662 57 40 0,000 0,18848406 0,20538205 ! RNA export from nucleus GO:0006405 61 41 0,000 0,19271261 0,20989608 ! mRNA catabolic process GO:0006402 79 41 0,000 0,19271261 0,20980255 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,19271261 0,20970909 ! regulation of hormone secretion GO:0046883 69 41 0,000 0,19271261 0,20961572 ! establishment or maintenance of cell polarity GO:0007163 96 41 0,000 0,19271261 0,20952244 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,19271261 0,20942923 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,19271261 0,20933611 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,19271261 0,20924307 GO:0015986|ATP synthesis coupled proton transport, ! spermatid differentiation GO:0048515 73 41 0,000 0,19271261 0,20915012 ! RNA modification GO:0009451 64 41 0,000 0,19271261 0,20905724 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,19691925 0,21352584 ! organic ether metabolic process GO:0018904 59 42 0,000 0,19691925 0,21343111 ! alcohol biosynthetic process GO:0046165 65 42 0,000 0,19691925 0,21333646 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,19691925 0,2132419 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,19691925 0,21314742 ! regulation of protein secretion GO:0050708 77 42 0,000 0,19691925 0,21305302 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,20110408 0,2174844 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,20110408 0,21738817 ! regulation of tube size GO:0035150 76 43 0,000 0,20110408 0,21729203 GO:0050880|regulation of blood vessel size, ! striated muscle cell differentiation GO:0051146 91 43 0,000 0,20110408 0,21719596 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,20110408 0,21709999 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,20110408 0,21700409 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,20110408 0,21690829 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,20110408 0,21681256 ! ion transmembrane transport GO:0034220 79 43 0,000 0,20110408 0,21671693 ! response to reactive oxygen species GO:0000302 75 44 0,000 0,20526722 0,22110574 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,20526722 0,2210083 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 0,000 0,20526722 0,22091094 ! striated muscle contraction GO:0006941 85 44 0,000 0,20526722 0,22081366 ! phagocytosis GO:0006909 105 44 0,000 0,20526722 0,22071647 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,20526722 0,22061937 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,20940879 0,22497171 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,20940879 0,22487282 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! biopolymer methylation GO:0043414 91 45 0,000 0,20940879 0,22477402 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,20940879 0,22467531 ! female gamete generation GO:0007292 71 45 0,000 0,20940879 0,22457668 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,20940879 0,22447814 ! polyol metabolic process GO:0019751 77 45 0,000 0,20940879 0,22437968 ! developmental growth GO:0048589 88 45 0,000 0,20940879 0,22428131 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,21352889 0,22859381 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,21352889 0,22849368 ! glycolysis GO:0006096 71 46 0,000 0,21352889 0,22839364 ! leukocyte migration GO:0050900 75 46 0,000 0,21352889 0,22829369 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,21352889 0,22819382 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,21352889 0,22809404 ! positive regulation of defense response GO:0031349 88 48 0,000 0,22170513 0,23672449 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,22170513 0,23662107 ! regulation of JAK-STAT cascade GO:0046425 76 48 0,000 0,22170513 0,23651774 ! endosome transport GO:0016197 127 48 0,000 0,22170513 0,2364145 ! male sex differentiation GO:0046661 93 48 0,000 0,22170513 0,23631135 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,22170513 0,2362083 ! regulation of inflammatory response GO:0050727 84 48 0,000 0,22170513 0,23610533 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,22170513 0,23600245 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,22170513 0,23589966 ! methylation GO:0032259 97 48 0,000 0,22170513 0,23579696 ! response to calcium ion GO:0051592 94 49 0,000 0,22576149 0,24000666 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,22576149 0,23990227 ! regulation of ion transport GO:0043269 86 50 0,000 0,22979682 0,24408419 ! induction of apoptosis by extracellular signals GO:0008624 99 50 0,000 0,22979682 0,24397811 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,22979682 0,24387212 ! regulation of gene expression, epigenetic GO:0040029 116 50 0,000 0,22979682 0,24376623 ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,22979682 0,24366043 ! regulation of cell projection organization GO:0031344 135 51 0,000 0,23381123 0,24780948 ! viral infectious cycle GO:0019058 104 51 0,000 0,23381123 0,24770201 ! peptide metabolic process GO:0006518 80 51 0,000 0,23381123 0,24759464 ! response to estrogen stimulus GO:0043627 98 52 0,000 0,23780483 0,25171456 ! Notch signaling pathway GO:0007219 111 52 0,000 0,23780483 0,25160555 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,23780483 0,25149663 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,23780483 0,2513878 ! excretion GO:0007588 87 52 0,000 0,23780483 0,25127907 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,23780483 0,25117043 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,23780483 0,25106189 ! amino acid activation GO:0043038 98 52 0,000 0,23780483 0,25095344 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,24177773 0,25503584 ! inner ear development GO:0048839 89 53 0,000 0,24177773 0,25492577 ! chromatin remodeling GO:0006338 122 53 0,000 0,24177773 0,25481579 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,24177773 0,25470591 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,24177773 0,25459612 ! vesicle organization GO:0016050 127 53 0,000 0,24177773 0,25448643 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,24573003 0,25853509 ! neuromuscular process GO:0050905 107 54 0,000 0,24573003 0,25842379 ! embryonic skeletal system development GO:0048706 101 54 0,000 0,24573003 0,2583126 ! regulation of muscle contraction GO:0006937 94 54 0,000 0,24573003 0,25820149 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,24573003 0,25809049 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,24573003 0,25797958 ! RNA catabolic process GO:0006401 103 55 0,000 0,24966184 0,2619948 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,24966184 0,2618823 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,24966184 0,26176991 ! regulation of multicellular organism growth GO:0040014 90 55 0,000 0,24966184 0,26165761 ! regulation of protein polymerization GO:0032271 117 55 0,000 0,24966184 0,26154541 ! glucose catabolic process GO:0006007 88 56 0,000 0,25357327 0,26552915 ! RNA elongation GO:0006354 90 56 0,000 0,25357327 0,26541538 ! chloride transport GO:0006821 102 57 0,000 0,25746441 0,26937283 ! regulation of actin filament length GO:0030832 118 58 0,000 0,26133538 0,2733058 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,26133538 0,27318885 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,26133538 0,273072 ! gastrulation GO:0007369 122 58 0,000 0,26133538 0,27295525 ! nuclear export GO:0051168 110 59 0,000 0,26518628 0,27685901 ! regulation of endocytosis GO:0030100 104 60 0,000 0,26901721 0,28073859 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,26901721 0,28061872 ! adult behavior GO:0030534 104 60 0,000 0,26901721 0,28049895 ! kidney development GO:0001822 133 60 0,000 0,26901721 0,28037929 ! positive regulation of secretion GO:0051047 110 61 0,000 0,27282827 0,28423005 ! regulation of cellular component size GO:0032535 125 61 0,000 0,27282827 0,2841089 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,27282827 0,28398785 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,27282827 0,2838669 ! cytokine-mediated signaling pathway GO:0019221 112 61 0,000 0,27282827 0,28374605 ! regulation of heart contraction GO:0008016 123 61 0,000 0,27282827 0,28362531 ! camera-type eye development GO:0043010 126 61 0,000 0,27282827 0,28350467 ! proton transport GO:0015992 117 61 0,000 0,27282827 0,28338413 ! negative regulation of response to stimulus GO:0048585 106 61 0,000 0,27282827 0,2832637 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,27661958 0,28707801 ! tRNA processing GO:0008033 102 62 0,000 0,27661958 0,2869561 ! regulation of protein complex assembly GO:0043254 132 63 0,000 0,28039122 0,29074522 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,28039122 0,29062187 ! hydrogen transport GO:0006818 121 64 0,000 0,2841433 0,29438596 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,2841433 0,29426116 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,28787592 0,29800037 ! multicellular organism reproduction GO:0032504 123 65 0,000 0,28787592 0,29787416 GO:0048609|reproductive process in a multicellular organism, ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,28787592 0,29774804 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,28787592 0,29762204 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,29158919 0,3013335 ! regulation of lipid metabolic process GO:0019216 132 66 0,000 0,29158919 0,30120608 ! gonad development GO:0008406 115 66 0,000 0,29158919 0,30107878 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,2952832 0,3047642 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,2952832 0,30463549 ! secondary metabolic process GO:0019748 125 67 0,000 0,2952832 0,3045069 ! myeloid cell differentiation GO:0030099 126 67 0,000 0,2952832 0,30437842 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,29895805 0,30803649 ! hexose catabolic process GO:0019320 113 68 0,000 0,29895805 0,30790662 ! extracellular matrix organization GO:0030198 146 68 0,000 0,29895805 0,30777687 ! negative regulation of ligase activity GO:0051352 116 68 0,000 0,29895805 0,30764722 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,29895805 0,30751769 ! cell projection assembly GO:0030031 138 68 0,000 0,29895805 0,30738826 ! homeostasis of number of cells GO:0048872 131 69 0,000 0,30261383 0,31101624 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,30261383 0,31088545 ! single fertilization GO:0007338 83 69 0,000 0,30261383 0,31075477 ! cell redox homeostasis GO:0045454 114 70 0,000 0,30625066 0,3143573 ! germ cell development GO:0007281 133 70 0,000 0,30625066 0,31422527 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,30986863 0,31780397 ! cAMP-mediated signaling GO:0019933 124 71 0,000 0,30986863 0,3176706 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,31346782 0,32122562 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,31346782 0,32109094 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,31704835 0,32462243 ! regulation of immune effector process GO:0002697 156 73 0,000 0,31704835 0,32448643 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 0,000 0,3206103 0,32799454 ! transition metal ion transport GO:0000041 143 75 0,000 0,32415378 0,33148082 ! eye development GO:0001654 155 75 0,000 0,32415378 0,33134213 ! regulation of actin cytoskeleton organization GO:0032956 167 76 0,000 0,32767887 0,33480531 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,32767887 0,33466534 ! regulation of blood pressure GO:0008217 134 76 0,000 0,32767887 0,33452548 ! amine catabolic process GO:0009310 136 77 0,000 0,33118568 0,33796433 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,33118568 0,33782322 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,33118568 0,33768223 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,33118568 0,33754135 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,33467429 0,34095467 ! antigen processing and presentation GO:0019882 117 78 0,000 0,33467429 0,34081254 ! fertilization GO:0009566 99 78 0,000 0,33467429 0,34067054 ! regulation of actin filament-based process GO:0032970 170 79 0,000 0,33814481 0,34405988 ! steroid biosynthetic process GO:0006694 146 79 0,000 0,33814481 0,34391664 ! response to steroid hormone stimulus GO:0048545 147 79 0,000 0,33814481 0,34377352 ! regulation of synaptic transmission GO:0050804 159 79 0,000 0,33814481 0,34363052 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 0,000 0,34159731 0,34699469 ! development of primary sexual characteristics GO:0045137 143 80 0,000 0,34159731 0,34685047 ! muscle cell differentiation GO:0042692 178 81 0,000 0,34503191 0,35019234 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 0,000 0,34503191 0,35004691 ! regulation of adenylate cyclase activity GO:0045761 165 83 0,000 0,35184773 0,35681362 ! exocytosis GO:0006887 153 83 0,000 0,35184773 0,35666556 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,35184773 0,35651763 ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,35184773 0,35636982 ! inorganic anion transport GO:0015698 156 83 0,000 0,35184773 0,35622213 ! response to metal ion GO:0010038 158 84 0,000 0,35522914 0,3594966 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,35859301 0,36275061 ! regulation of cyclase activity GO:0031279 168 85 0,000 0,35859301 0,36260046 ! regulation of transmission of nerve impulse GO:0051969 167 85 0,000 0,35859301 0,36245044 ! regulation of cAMP biosynthetic process GO:0030817 173 86 0,000 0,36193941 0,36568155 ! regulation of lyase activity GO:0051339 169 86 0,000 0,36193941 0,36553038 ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,36526846 0,36874002 ! alcohol catabolic process GO:0046164 142 87 0,000 0,36526846 0,36858771 ! cellular respiration GO:0045333 143 88 0,000 0,36858022 0,37177601 ! sensory perception of smell GO:0007608 117 88 0,000 0,36858022 0,37162257 ! regulation of cAMP metabolic process GO:0030814 182 89 0,000 0,3718748 0,37478967 ! cellular defense response GO:0006968 123 89 0,000 0,3718748 0,37463511 ! regulation of neurological system process GO:0031644 175 89 0,000 0,3718748 0,37448069 ! response to inorganic substance GO:0010035 173 90 0,000 0,37515229 0,37762548 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,37515229 0,37746995 ! positive regulation of protein modification process GO:0031401 156 90 0,000 0,37515229 0,37731455 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 0,000 0,37841276 0,38043719 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! defense response to bacterium GO:0042742 112 91 0,000 0,37841276 0,3802807 ! vitamin metabolic process GO:0006766 153 93 0,000 0,38488303 0,38662387 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,388093 0,38968812 ! female pregnancy GO:0007565 166 94 0,000 0,388093 0,38952802 ! sterol metabolic process GO:0016125 166 94 0,000 0,388093 0,38936805 ! carbohydrate biosynthetic process GO:0016051 158 94 0,000 0,388093 0,38920821 ! regulation of defense response GO:0031347 171 95 0,000 0,39128631 0,39224967 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,39128631 0,39208878 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 0,000 0,39128631 0,39192802 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,39128631 0,3917674 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,39128631 0,3916069 ! regulation of nucleotide metabolic process GO:0006140 197 98 0,000 0,40076713 0,40093124 ! mRNA transport GO:0051028 185 100 0,000 0,40700593 0,40700593