pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6693-VanDeVijver-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/vantveer-oligo_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! androgen receptor signaling pathway GO:0030521 24 24 4,000 3,691E-07 6,803E-04 ! positive regulation of MAP kinase activity GO:0043406 50 49 5,000 6,283E-07 5,79E-04 ! positive regulation of protein kinase activity GO:0045860 89 86 6,000 1,151E-06 7,07E-04 ! positive regulation of transferase activity GO:0051347 91 88 6,000 1,347E-06 6,204E-04 GO:0033674|positive regulation of kinase activity, ! actin cytoskeleton reorganization GO:0031532 5 5 2,000 2,592E-06 9,553E-04 ! regulation of MAP kinase activity GO:0043405 67 66 5,000 3,757E-06 1,154E-03 ! steroid hormone receptor signaling pathway GO:0030518 38 38 4,000 4,073E-06 1,072E-03 ! intracellular receptor-mediated signaling pathway GO:0030522 40 40 4,000 5,287E-06 1,218E-03 ! negative regulation of protein transport GO:0051224 21 21 3,000 8,814E-06 1,805E-03 ! cytoplasmic sequestering of protein GO:0051220 8 8 2,000 1,431E-05 2,638E-03 ! regulation of intracellular protein transport GO:0033157 25 25 3,000 1,828E-05 3,062E-03 ! regulation of nucleocytoplasmic transport GO:0046822 27 27 3,000 2,512E-05 3,858E-03 ! negative regulation of nucleocytoplasmic transport GO:0046823 10 10 2,000 3,039E-05 4,309E-03 ! response to UV GO:0009411 29 29 3,000 3,367E-05 4,432E-03 ! regulation of protein amino acid phosphorylation GO:0001932 62 61 4,000 4,317E-05 5,304E-03 ! regulation of intracellular transport GO:0032386 31 31 3,000 4,418E-05 5,089E-03 ! G1 phase GO:0051318 13 12 2,000 5,521E-05 5,986E-03 ! regulation of protein catabolic process GO:0042176 35 34 3,000 6,419E-05 6,572E-03 ! negative regulation of protein catabolic process GO:0042177 13 13 2,000 7,145E-05 6,931E-03 ! cell aging GO:0007569 13 13 2,000 7,145E-05 6,584E-03 ! negative regulation of intracellular transport GO:0032387 13 13 2,000 7,145E-05 6,271E-03 ! activation of JUN kinase activity GO:0007257 13 13 2,000 7,145E-05 5,986E-03 ! response to radiation GO:0009314 70 68 4,000 7,311E-05 5,859E-03 ! negative regulation of protein kinase activity GO:0006469 37 37 3,000 9,012E-05 6,92E-03 ! positive regulation of epithelial cell proliferation GO:0050679 14 14 2,000 9,052E-05 6,673E-03 ! base-excision repair GO:0006284 14 14 2,000 9,052E-05 6,417E-03 ! negative regulation of kinase activity GO:0033673 38 38 3,000 1,002E-04 6,842E-03 ! activation of MAPK activity GO:0000187 39 39 3,000 1,112E-04 7,317E-03 ! regulation of transcription factor import into nucleus GO:0042990 15 15 2,000 1,126E-04 7,158E-03 ! response to ionizing radiation GO:0010212 16 15 2,000 1,126E-04 6,919E-03 ! negative regulation of transferase activity GO:0051348 40 40 3,000 1,229E-04 7,308E-03 ! regulation of JUN kinase activity GO:0043506 17 16 2,000 1,38E-04 7,948E-03 GO:0043507|positive regulation of JUN kinase activity, ! regulation of protein modification process GO:0031399 79 78 4,000 1,411E-04 7,878E-03 ! MAPKKK cascade GO:0000165 82 81 4,000 1,687E-04 9,145E-03 ! negative regulation of DNA binding GO:0043392 19 18 2,000 1,992E-04 0,01049151 ! negative regulation of catabolic process GO:0009895 18 18 2,000 1,992E-04 0,01020008 ! regulation of catabolic process GO:0009894 48 47 3,000 2,32E-04 0,0115585 ! DNA recombination GO:0006310 48 48 3,000 2,519E-04 0,0122191 ! cell cycle arrest GO:0007050 49 49 3,000 2,73E-04 0,01290247 ! negative regulation of binding GO:0051100 21 20 2,000 2,758E-04 0,01270823 ! negative regulation of transport GO:0051051 51 50 3,000 2,954E-04 0,01327692 ! regulation of neurogenesis GO:0050767 51 50 3,000 2,954E-04 0,0129608 ! interphase of mitotic cell cycle GO:0051329 52 51 3,000 3,19E-04 0,01367151 GO:0051325|interphase, ! G1/S transition of mitotic cell cycle GO:0000082 21 21 2,000 3,203E-04 0,01341689 ! regulation of protein import into nucleus GO:0042306 21 21 2,000 3,203E-04 0,01311873 ! response to light stimulus GO:0009416 53 52 3,000 3,439E-04 0,0137791 ! maintenance of protein location in cell GO:0032507 23 22 2,000 3,692E-04 0,01447734 ! regulation of protein transport GO:0051223 53 53 3,000 3,702E-04 0,01421508 GO:0070201|regulation of establishment of protein localization, ! regulation of cell growth GO:0001558 97 96 4,000 3,743E-04 0,01407648 ! DNA synthesis during DNA repair GO:0000731 5 5 1,000 4,132E-04 0,01522886 ! mRNA stabilization GO:0048255 5 5 1,000 4,132E-04 0,01493026 GO:0043489|RNA stabilization, ! 2-oxoglutarate metabolic process GO:0006103 5 5 1,000 4,132E-04 0,01464314 ! dopamine receptor signaling pathway GO:0007212 5 5 1,000 4,132E-04 0,01436685 ! insulin-like growth factor receptor signaling pathway GO:0048009 5 5 1,000 4,132E-04 0,0141008 ! regulation of phospholipase A2 activity GO:0032429 5 5 1,000 4,132E-04 0,01384442 ! receptor clustering GO:0043113 5 5 1,000 4,132E-04 0,0135972 ! enucleate erythrocyte differentiation GO:0043353 6 5 1,000 4,132E-04 0,01335865 ! DNA methylation GO:0006306 5 5 1,000 4,132E-04 0,01312833 GO:0006305|DNA alkylation, ! T cell lineage commitment GO:0002360 5 5 1,000 4,132E-04 0,01290581 ! negative regulation of neuroblast proliferation GO:0007406 5 5 1,000 4,132E-04 0,01269072 ! positive regulation of viral reproduction GO:0048524 5 5 1,000 4,132E-04 0,01248267 ! pyrimidine base metabolic process GO:0006206 5 5 1,000 4,132E-04 0,01228134 ! positive regulation of blood vessel endothelial cell migration GO:0043536 5 5 1,000 4,132E-04 0,0120864 ! lysogeny GO:0030069 5 5 1,000 4,132E-04 0,01189755 GO:0019047|provirus integration, ! regulation of JNK cascade GO:0046328 25 23 2,000 4,226E-04 0,01198353 ! regulation of nervous system development GO:0051960 57 56 3,000 4,578E-04 0,01278335 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 26 24 2,000 4,808E-04 0,01322602 ! maintenance of protein location GO:0045185 25 24 2,000 4,808E-04 0,01303152 ! regulation of protein localization GO:0032880 58 57 3,000 4,9E-04 0,01308793 ! regulation of cell development GO:0060284 60 59 3,000 5,592E-04 0,01472352 ! double-strand break repair GO:0006302 27 26 2,000 6,12E-04 0,01588684 ! maintenance of location in cell GO:0051651 27 26 2,000 6,12E-04 0,01566619 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 6 6 1,000 6,172E-04 0,01558096 ! regulation of lipid kinase activity GO:0043550 6 6 1,000 6,172E-04 0,01537041 ! cartilage condensation GO:0001502 7 6 1,000 6,172E-04 0,01516547 ! regulation of positive chemotaxis GO:0050926 6 6 1,000 6,172E-04 0,01496592 GO:0050927|positive regulation of positive chemotaxis, ! succinate metabolic process GO:0006105 7 6 1,000 6,172E-04 0,01477156 ! cytoplasmic sequestering of transcription factor GO:0042994 6 6 1,000 6,172E-04 0,01458218 ! positive regulation of transcription factor import into nucleus GO:0042993 6 6 1,000 6,172E-04 0,0143976 ! ER overload response GO:0006983 6 6 1,000 6,172E-04 0,01421763 ! V(D)J recombination GO:0033151 6 6 1,000 6,172E-04 0,0140421 ! negative regulation of T cell proliferation GO:0042130 6 6 1,000 6,172E-04 0,01387085 GO:0070667|negative regulation of mast cell proliferation, ! regulation of vascular permeability GO:0043114 6 6 1,000 6,172E-04 0,01370374 ! regulation of bone resorption GO:0045124 6 6 1,000 6,172E-04 0,0135406 ! G1 DNA damage checkpoint GO:0031571 6 6 1,000 6,172E-04 0,0133813 ! regulation of T cell differentiation in the thymus GO:0033081 6 6 1,000 6,172E-04 0,0132257 ! phosphoinositide 3-kinase cascade GO:0014065 6 6 1,000 6,172E-04 0,01307368 ! multicellular organismal aging GO:0010259 6 6 1,000 6,172E-04 0,01292511 ! nitric oxide metabolic process GO:0046209 6 6 1,000 6,172E-04 0,01277989 GO:0006809|nitric oxide biosynthetic process, ! localization within membrane GO:0051668 6 6 1,000 6,172E-04 0,01263789 ! stress-activated protein kinase signaling pathway GO:0031098 28 28 2,000 7,641E-04 0,01547589 GO:0007254|JNK cascade, ! protein amino acid autophosphorylation GO:0046777 28 28 2,000 7,641E-04 0,01530768 ! regulation of epithelial cell proliferation GO:0050678 29 29 2,000 8,484E-04 0,01681337 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 7 7 1,000 8,604E-04 0,01686966 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 7 7 1,000 8,604E-04 0,01669209 ! oxaloacetate metabolic process GO:0006107 7 7 1,000 8,604E-04 0,01651821 ! axis specification GO:0009798 7 7 1,000 8,604E-04 0,01634792 ! regulation of mRNA processing GO:0050684 7 7 1,000 8,604E-04 0,01618111 ! negative regulation of lymphocyte proliferation GO:0050672 7 7 1,000 8,604E-04 0,01601766 GO:0032945|negative regulation of mononuclear cell proliferation, GO:0070664|negative regulation of leukocyte proliferation, ! response to X-ray GO:0010165 7 7 1,000 8,604E-04 0,01585748 ! regulation of intracellular pH GO:0051453 7 7 1,000 8,604E-04 0,01570048 ! DNA integration GO:0015074 7 7 1,000 8,604E-04 0,01554655 ! platelet activation GO:0030168 8 7 1,000 8,604E-04 0,01539562 ! response to gamma radiation GO:0010332 8 7 1,000 8,604E-04 0,01524758 ! synaptic transmission, cholinergic GO:0007271 7 7 1,000 8,604E-04 0,01510237 ! regulation of macrophage differentiation GO:0045649 8 7 1,000 8,604E-04 0,01495989 ! regulation of mRNA stability GO:0043488 7 7 1,000 8,604E-04 0,01482008 ! negative regulation of T cell activation GO:0050868 7 7 1,000 8,604E-04 0,01468286 ! regulation of mitotic cell cycle GO:0007346 72 69 3,000 1,013E-03 0,01712614 ! aging GO:0007568 32 31 2,000 1,034E-03 0,01732764 ! regulation of DNA replication GO:0006275 32 31 2,000 1,034E-03 0,01717153 ! negative regulation of cell growth GO:0030308 32 32 2,000 1,136E-03 0,01869318 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 32 32 2,000 1,136E-03 0,01852775 ! maintenance of location GO:0051235 33 32 2,000 1,136E-03 0,01836523 ! negative regulation of bone remodeling GO:0046851 8 8 1,000 1,142E-03 0,01830902 ! negative regulation of transcription factor import into nucleus GO:0042992 8 8 1,000 1,142E-03 0,01815118 ! negative regulation of proteolysis GO:0045861 8 8 1,000 1,142E-03 0,01799604 ! phosphagen metabolic process GO:0006599 8 8 1,000 1,142E-03 0,01784354 GO:0006600|creatine metabolic process, ! cell-cell junction assembly GO:0007043 8 8 1,000 1,142E-03 0,01769359 ! positive regulation of endothelial cell migration GO:0010595 8 8 1,000 1,142E-03 0,01754614 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 8 8 1,000 1,142E-03 0,01740113 ! positive regulation of myeloid leukocyte differentiation GO:0002763 9 8 1,000 1,142E-03 0,0172585 ! positive regulation of leukocyte migration GO:0002687 8 8 1,000 1,142E-03 0,01711819 ! branched chain family amino acid metabolic process GO:0009081 8 8 1,000 1,142E-03 0,01698014 ! regulation of RNA stability GO:0043487 8 8 1,000 1,142E-03 0,0168443 ! release of cytochrome c from mitochondria GO:0001836 9 8 1,000 1,142E-03 0,01671061 ! positive regulation of hydrolase activity GO:0051345 72 72 3,000 1,188E-03 0,01724448 ! negative regulation of cell size GO:0045792 33 33 2,000 1,244E-03 0,01791024 ! regulation of cellular response to stress GO:0080135 35 33 2,000 1,244E-03 0,0177714 ! activation of protein kinase activity GO:0032147 35 33 2,000 1,244E-03 0,0176347 ! response to oxidative stress GO:0006979 76 75 3,000 1,384E-03 0,01947159 ! positive regulation of cell projection organization GO:0031346 9 9 1,000 1,463E-03 0,02042322 ! regulation of membrane protein ectodomain proteolysis GO:0051043 9 9 1,000 1,463E-03 0,02026966 ! regulation of nitric-oxide synthase activity GO:0050999 9 9 1,000 1,463E-03 0,02011839 ! positive regulation of endothelial cell proliferation GO:0001938 9 9 1,000 1,463E-03 0,01996937 ! platelet-derived growth factor receptor signaling pathway GO:0048008 9 9 1,000 1,463E-03 0,01982253 ! glutamine metabolic process GO:0006541 9 9 1,000 1,463E-03 0,01967784 ! nucleobase biosynthetic process GO:0046112 9 9 1,000 1,463E-03 0,01953525 ! negative regulation of protein import into nucleus GO:0042308 9 9 1,000 1,463E-03 0,01939471 ! positive regulation of protein import into nucleus GO:0042307 9 9 1,000 1,463E-03 0,01925617 ! regulation of cellular pH GO:0030641 9 9 1,000 1,463E-03 0,01911961 ! negative regulation of tissue remodeling GO:0034104 9 9 1,000 1,463E-03 0,01898496 ! regulation of leukocyte migration GO:0002685 9 9 1,000 1,463E-03 0,0188522 ! regulation of blood vessel endothelial cell migration GO:0043535 9 9 1,000 1,463E-03 0,01872128 ! positive regulation of phosphorylation GO:0042327 35 35 2,000 1,479E-03 0,01879382 ! positive regulation of protein kinase cascade GO:0010740 79 78 3,000 1,601E-03 0,02021352 ! positive regulation of cell migration GO:0030335 36 36 2,000 1,606E-03 0,02013136 ! positive regulation of phosphorus metabolic process GO:0010562 36 36 2,000 1,606E-03 0,01999534 GO:0045937|positive regulation of phosphate metabolic process, ! response to drug GO:0042493 37 37 2,000 1,739E-03 0,02151524 ! negative regulation of growth GO:0045926 37 37 2,000 1,739E-03 0,02137181 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 10 10 1,000 1,821E-03 0,02222402 ! neuron maturation GO:0042551 10 10 1,000 1,821E-03 0,02207781 ! apoptotic mitochondrial changes GO:0008637 11 10 1,000 1,821E-03 0,02193351 ! induction of apoptosis via death domain receptors GO:0008625 10 10 1,000 1,821E-03 0,02179108 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 10 10 1,000 1,821E-03 0,02165049 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! neuromuscular junction development GO:0007528 10 10 1,000 1,821E-03 0,02151171 ! epithelial to mesenchymal transition GO:0001837 10 10 1,000 1,821E-03 0,02137469 ! positive regulation of neuron apoptosis GO:0043525 10 10 1,000 1,821E-03 0,02123941 ! negative regulation of homeostatic process GO:0032845 10 10 1,000 1,821E-03 0,02110583 ! protein stabilization GO:0050821 10 10 1,000 1,821E-03 0,02097392 ! regulation of MAPKKK cascade GO:0043408 41 39 2,000 2,027E-03 0,02320726 ! protein oligomerization GO:0051259 39 39 2,000 2,027E-03 0,02306401 ! positive regulation of cell motion GO:0051272 39 39 2,000 2,027E-03 0,02292251 ! regulation of cellular localization GO:0060341 86 85 3,000 2,199E-03 0,02470848 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 11 11 1,000 2,216E-03 0,02475471 ! G1 phase of mitotic cell cycle GO:0000080 12 11 1,000 2,216E-03 0,02460559 ! signal complex assembly GO:0007172 11 11 1,000 2,216E-03 0,02445825 ! positive regulation of nucleocytoplasmic transport GO:0046824 11 11 1,000 2,216E-03 0,02431267 GO:0032388|positive regulation of intracellular transport, ! regulation of viral genome replication GO:0045069 11 11 1,000 2,216E-03 0,0241688 ! activation of MAPKK activity GO:0000186 12 11 1,000 2,216E-03 0,02402663 ! cellular response to starvation GO:0009267 11 11 1,000 2,216E-03 0,02388613 ! positive regulation of nitric oxide biosynthetic process GO:0045429 11 11 1,000 2,216E-03 0,02374725 ! apoptotic nuclear changes GO:0030262 11 11 1,000 2,216E-03 0,02360999 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 11 11 1,000 2,216E-03 0,0234743 ! G1/S transition checkpoint GO:0031575 12 11 1,000 2,216E-03 0,02334016 ! regulation of monooxygenase activity GO:0032768 11 11 1,000 2,216E-03 0,02320754 ! negative regulation of lymphocyte activation GO:0051250 11 11 1,000 2,216E-03 0,02307643 ! cell cycle checkpoint GO:0000075 42 41 2,000 2,343E-03 0,02426217 ! cell-substrate adhesion GO:0031589 43 42 2,000 2,512E-03 0,02586441 ! positive regulation of protein catabolic process GO:0045732 12 12 1,000 2,648E-03 0,02711712 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 12 12 1,000 2,648E-03 0,0269673 ! initiation of viral infection GO:0019059 12 12 1,000 2,648E-03 0,02681913 ! protein amino acid ADP-ribosylation GO:0006471 12 12 1,000 2,648E-03 0,02667258 ! xenobiotic metabolic process GO:0006805 12 12 1,000 2,648E-03 0,02652762 ! fibroblast growth factor receptor signaling pathway GO:0008543 12 12 1,000 2,648E-03 0,02638422 ! positive regulation of multicellular organism growth GO:0040018 12 12 1,000 2,648E-03 0,02624237 ! pyrimidine nucleotide biosynthetic process GO:0006221 12 12 1,000 2,648E-03 0,02610204 ! cellular monovalent inorganic cation homeostasis GO:0030004 12 12 1,000 2,648E-03 0,0259632 ! negative regulation of cell cycle GO:0045786 92 91 3,000 2,821E-03 0,02750616 ! DNA replication GO:0006260 91 91 3,000 2,821E-03 0,02736139 ! regulation of DNA binding GO:0051101 47 45 2,000 3,063E-03 0,02955487 ! phosphoinositide-mediated signaling GO:0048015 45 45 2,000 3,063E-03 0,02940094 ! positive regulation of smooth muscle cell proliferation GO:0048661 13 13 1,000 3,117E-03 0,02976481 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 13 13 1,000 3,117E-03 0,02961138 GO:0016444|somatic cell DNA recombination, ! G2/M transition of mitotic cell cycle GO:0000086 13 13 1,000 3,117E-03 0,02945953 ! positive regulation of JAK-STAT cascade GO:0046427 13 13 1,000 3,117E-03 0,02930923 ! vasculogenesis GO:0001570 13 13 1,000 3,117E-03 0,02916045 ! mitochondrial membrane organization GO:0007006 13 13 1,000 3,117E-03 0,02901317 ! regulation of nitric oxide biosynthetic process GO:0045428 13 13 1,000 3,117E-03 0,02886738 ! negative regulation of DNA replication GO:0008156 13 13 1,000 3,117E-03 0,02872304 ! receptor metabolic process GO:0043112 14 13 1,000 3,117E-03 0,02858014 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 13 13 1,000 3,117E-03 0,02843866 ! regulation of endothelial cell migration GO:0010594 13 13 1,000 3,117E-03 0,02829856 ! response to endoplasmic reticulum stress GO:0034976 13 13 1,000 3,117E-03 0,02815985 ! regulation of viral reproduction GO:0050792 13 13 1,000 3,117E-03 0,02802248 ! nucleobase metabolic process GO:0009112 13 13 1,000 3,117E-03 0,02788645 ! positive regulation of neurogenesis GO:0050769 13 13 1,000 3,117E-03 0,02775173 ! positive regulation of locomotion GO:0040017 13 13 1,000 3,117E-03 0,02761831 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, GO:0050920|regulation of chemotaxis, ! negative regulation of Wnt receptor signaling pathway GO:0030178 13 13 1,000 3,117E-03 0,02748617 ! negative regulation of leukocyte activation GO:0002695 13 13 1,000 3,117E-03 0,02735528 ! cell-cell junction organization GO:0045216 13 13 1,000 3,117E-03 0,02722563 ! telomere organization GO:0032200 13 13 1,000 3,117E-03 0,02709721 GO:0000723|telomere maintenance, ! tissue homeostasis GO:0001894 13 13 1,000 3,117E-03 0,02696999 GO:0048871|multicellular organismal homeostasis, ! protein tetramerization GO:0051262 13 13 1,000 3,117E-03 0,02684397 ! calcium-dependent cell-cell adhesion GO:0016339 14 14 1,000 3,621E-03 0,03104297 ! regulation of behavior GO:0050795 14 14 1,000 3,621E-03 0,03089925 ! DNA modification GO:0006304 14 14 1,000 3,621E-03 0,03075686 ! actin filament organization GO:0007015 50 48 2,000 3,683E-03 0,03113432 ! ossification GO:0001503 50 49 2,000 3,905E-03 0,03286353 GO:0060348|bone development, ! negative regulation of transcription from RNA polymerase II promoter GO:0000122 103 100 3,000 3,966E-03 0,03322109 ! regulation of DNA metabolic process GO:0051052 51 50 2,000 4,136E-03 0,03448759 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 50 50 2,000 4,136E-03 0,03433224 ! anatomical structure homeostasis GO:0060249 51 50 2,000 4,136E-03 0,03417828 ! protein import into nucleus, translocation GO:0000060 15 15 1,000 4,161E-03 0,03423709 ! striated muscle cell differentiation GO:0051146 16 15 1,000 4,161E-03 0,03408493 ! ER-nuclear signaling pathway GO:0006984 15 15 1,000 4,161E-03 0,03393411 ! chromosome condensation GO:0030261 15 15 1,000 4,161E-03 0,03378462 ! response to starvation GO:0042594 15 15 1,000 4,161E-03 0,03363644 ! positive regulation of myeloid cell differentiation GO:0045639 16 15 1,000 4,161E-03 0,03348956 ! negative regulation of transcription factor activity GO:0043433 16 15 1,000 4,161E-03 0,03334395 GO:0090048|negative regulation of transcription regulator activity, ! somatic diversification of immune receptors GO:0002200 15 15 1,000 4,161E-03 0,0331996 ! negative regulation of cell activation GO:0050866 15 15 1,000 4,161E-03 0,0330565 ! protein homooligomerization GO:0051260 15 15 1,000 4,161E-03 0,03291463 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 52 52 2,000 4,621E-03 0,03639368 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 16 16 1,000 4,736E-03 0,03714197 ! negative regulation of adenylate cyclase activity GO:0007194 16 16 1,000 4,736E-03 0,03698459 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! regulation of synaptic plasticity GO:0048167 16 16 1,000 4,736E-03 0,03682854 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 16 16 1,000 4,736E-03 0,0366738 ! cellular response to reactive oxygen species GO:0034614 16 16 1,000 4,736E-03 0,03652035 ! positive regulation of cell development GO:0010720 16 16 1,000 4,736E-03 0,03636818 ! regulation of myeloid leukocyte differentiation GO:0002761 17 16 1,000 4,736E-03 0,03621728 ! cellular response to nutrient levels GO:0031669 16 16 1,000 4,736E-03 0,03606762 ! positive regulation of catabolic process GO:0009896 16 16 1,000 4,736E-03 0,03591919 ! response to xenobiotic stimulus GO:0009410 16 16 1,000 4,736E-03 0,03577198 ! protein amino acid dephosphorylation GO:0006470 55 54 2,000 5,139E-03 0,03865961 ! regulation of fibroblast proliferation GO:0048145 17 17 1,000 5,345E-03 0,04004536 ! regulation of smooth muscle cell proliferation GO:0048660 17 17 1,000 5,345E-03 0,03988323 ! positive regulation of cell adhesion GO:0045785 17 17 1,000 5,345E-03 0,03972241 ! myelination GO:0042552 17 17 1,000 5,345E-03 0,03956288 ! dicarboxylic acid metabolic process GO:0043648 18 17 1,000 5,345E-03 0,03940463 ! cell junction assembly GO:0034329 18 17 1,000 5,345E-03 0,03924764 ! tissue remodeling GO:0048771 17 17 1,000 5,345E-03 0,0390919 ! response to toxin GO:0009636 18 17 1,000 5,345E-03 0,03893738 ! negative regulation of cell development GO:0010721 18 17 1,000 5,345E-03 0,03878409 GO:0050768|negative regulation of neurogenesis, ! regulation of oxidoreductase activity GO:0051341 17 17 1,000 5,345E-03 0,03863199 ! myeloid leukocyte activation GO:0002274 18 17 1,000 5,345E-03 0,03848109 ! liver development GO:0001889 17 17 1,000 5,345E-03 0,03833135 ! regulation of cell adhesion GO:0030155 56 55 2,000 5,411E-03 0,03865361 ! regulation of binding GO:0051098 60 57 2,000 5,98E-03 0,04255573 ! regulation of cell projection organization GO:0031344 19 18 1,000 5,988E-03 0,04244866 ! epidermal growth factor receptor signaling pathway GO:0007173 18 18 1,000 5,988E-03 0,04228603 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 18 18 1,000 5,988E-03 0,04212463 ! B cell differentiation GO:0030183 18 18 1,000 5,988E-03 0,04196446 ! cellular response to extracellular stimulus GO:0031668 18 18 1,000 5,988E-03 0,0418055 ! ensheathment of neurons GO:0007272 18 18 1,000 5,988E-03 0,04164775 GO:0008366|axon ensheathment, ! dephosphorylation GO:0016311 60 59 2,000 6,584E-03 0,04562071 ! DNA damage checkpoint GO:0000077 19 19 1,000 6,665E-03 0,04600755 ! negative regulation of DNA metabolic process GO:0051053 19 19 1,000 6,665E-03 0,04583588 ! regulation of pH GO:0006885 19 19 1,000 6,665E-03 0,04566549 ! regulation of JAK-STAT cascade GO:0046425 19 19 1,000 6,665E-03 0,04549636 ! regulation of endothelial cell proliferation GO:0001936 19 19 1,000 6,665E-03 0,04532847 ! multicellular organismal metabolic process GO:0044236 19 19 1,000 6,665E-03 0,04516182 ! peptidyl-tyrosine phosphorylation GO:0018108 20 19 1,000 6,665E-03 0,0449964 ! cellular response to oxidative stress GO:0034599 19 19 1,000 6,665E-03 0,04483218 ! peripheral nervous system development GO:0007422 19 19 1,000 6,665E-03 0,04466915 ! regulation of protein stability GO:0031647 19 19 1,000 6,665E-03 0,04450731 ! dorsal/ventral pattern formation GO:0009953 19 19 1,000 6,665E-03 0,04434663 ! regulation of cell shape GO:0008360 21 19 1,000 6,665E-03 0,04418711 ! placenta development GO:0001890 19 19 1,000 6,665E-03 0,04402873 ! response to heat GO:0009408 19 19 1,000 6,665E-03 0,04387149 ! negative regulation of cell adhesion GO:0007162 21 20 1,000 7,375E-03 0,04837162 ! nucleus organization GO:0006997 20 20 1,000 7,375E-03 0,04820009 ! positive regulation of gene-specific transcription GO:0043193 20 20 1,000 7,375E-03 0,04802977 ! peptidyl-tyrosine modification GO:0018212 21 20 1,000 7,375E-03 0,04786065 ! mammary gland development GO:0030879 23 21 1,000 8,118E-03 0,05249497 ! DNA integrity checkpoint GO:0031570 21 21 1,000 8,118E-03 0,05231142 ! regulation of action potential in neuron GO:0019228 21 21 1,000 8,118E-03 0,05212915 ! regulation of multicellular organism growth GO:0040014 21 21 1,000 8,118E-03 0,05194815 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 21 21 1,000 8,118E-03 0,0517684 ! regulation of proteolysis GO:0030162 21 21 1,000 8,118E-03 0,05158988 ! negative regulation of hydrolase activity GO:0051346 21 21 1,000 8,118E-03 0,0514126 ! angiogenesis GO:0001525 65 64 2,000 8,249E-03 0,05206755 ! positive regulation of protein metabolic process GO:0051247 64 64 2,000 8,249E-03 0,05188985 ! cellular amide metabolic process GO:0043603 22 22 1,000 8,893E-03 0,05574534 ! cell junction organization GO:0034330 23 22 1,000 8,893E-03 0,05555637 ! erythrocyte differentiation GO:0030218 23 22 1,000 8,893E-03 0,05536868 ! biopolymer methylation GO:0043414 22 22 1,000 8,893E-03 0,05518225 GO:0032259|methylation, ! regulation of Wnt receptor signaling pathway GO:0030111 23 22 1,000 8,893E-03 0,05499708 ! cytokinesis GO:0000910 23 22 1,000 8,893E-03 0,05481314 ! pyrimidine nucleotide metabolic process GO:0006220 22 22 1,000 8,893E-03 0,05463043 ! negative regulation of protein metabolic process GO:0051248 66 66 2,000 8,979E-03 0,05497576 ! striated muscle tissue development GO:0014706 69 67 2,000 9,357E-03 0,05710283 ! viral infectious cycle GO:0019058 23 23 1,000 9,699E-03 0,05899609 ! mitotic cell cycle checkpoint GO:0007093 24 23 1,000 9,699E-03 0,05880202 ! induction of apoptosis by extracellular signals GO:0008624 23 23 1,000 9,699E-03 0,05860923 ! positive regulation of growth GO:0045927 23 23 1,000 9,699E-03 0,0584177 ! monovalent inorganic cation homeostasis GO:0055067 23 23 1,000 9,699E-03 0,05822741 ! calcium-mediated signaling GO:0019722 23 23 1,000 9,699E-03 0,05803836 ! regulation of cell size GO:0008361 68 68 2,000 9,745E-03 0,05812113 ! mitochondrial transport GO:0006839 24 24 1,000 0,01053735 0,06264623 ! regulation of action potential GO:0001508 24 24 1,000 0,01053735 0,06244479 ! T cell differentiation GO:0030217 24 24 1,000 0,01053735 0,06224465 ! erythrocyte homeostasis GO:0034101 25 24 1,000 0,01053735 0,06204578 ! wound healing GO:0042060 74 70 2,000 0,0105478 0,06190952 ! muscle tissue development GO:0060537 72 70 2,000 0,0105478 0,06171298 ! regulation of cell migration GO:0030334 71 71 2,000 0,01096339 0,06394156 ! regulation of gene-specific transcription GO:0032583 25 25 1,000 0,01140634 0,06631511 ! endosome transport GO:0016197 25 25 1,000 0,01140634 0,06610658 ! regulation of T cell proliferation GO:0042129 25 25 1,000 0,01140634 0,06589934 ! negative regulation of immune system process GO:0002683 25 25 1,000 0,01140634 0,06569341 ! JAK-STAT cascade GO:0007259 26 25 1,000 0,01140634 0,06548876 ! transforming growth factor beta receptor signaling pathway GO:0007179 26 26 1,000 0,01230587 0,07043391 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 26 26 1,000 0,01230587 0,07021585 ! induction of apoptosis by intracellular signals GO:0008629 26 26 1,000 0,01230587 0,06999913 ! regulation of T cell differentiation GO:0045580 26 26 1,000 0,01230587 0,06978375 ! synapse organization GO:0050808 26 26 1,000 0,01230587 0,06956969 ! cAMP-mediated signaling GO:0019933 27 27 1,000 0,01323551 0,07459646 ! activation of caspase activity GO:0006919 27 27 1,000 0,01323551 0,07436903 ! mesenchymal cell development GO:0014031 29 27 1,000 0,01323551 0,07414298 GO:0060485|mesenchyme development, GO:0048762|mesenchymal cell differentiation, ! glutamine family amino acid metabolic process GO:0009064 28 27 1,000 0,01323551 0,07391831 ! cell morphogenesis involved in differentiation GO:0000904 82 77 2,000 0,01365579 0,07603513 ! regulation of mast cell proliferation GO:0070666 28 28 1,000 0,01419484 0,07879849 ! cartilage development GO:0051216 29 28 1,000 0,01419484 0,07856186 ! regulation of locomotion GO:0040012 79 79 2,000 0,01462979 0,08072665 ! regulation of cell motion GO:0051270 79 79 2,000 0,01462979 0,08048567 ! positive regulation of cell cycle GO:0045787 29 29 1,000 0,01518347 0,08328313 ! viral reproductive process GO:0022415 29 29 1,000 0,01518347 0,083036 ! regulation of lymphocyte proliferation GO:0050670 29 29 1,000 0,01518347 0,08279033 GO:0032944|regulation of mononuclear cell proliferation, GO:0070663|regulation of leukocyte proliferation, ! DNA-dependent DNA replication GO:0006261 29 29 1,000 0,01518347 0,08254611 ! regulation of gene expression, epigenetic GO:0040029 29 29 1,000 0,01518347 0,08230333 ! positive regulation of protein transport GO:0051222 29 29 1,000 0,01518347 0,08206197 ! response to reactive oxygen species GO:0000302 31 30 1,000 0,01620097 0,08730524 ! positive regulation of peptidase activity GO:0010952 30 30 1,000 0,01620097 0,08705071 GO:0043280|positive regulation of caspase activity, ! activation of phospholipase C activity GO:0007202 30 30 1,000 0,01620097 0,08679766 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of response to external stimulus GO:0032103 30 30 1,000 0,01620097 0,08654607 ! positive regulation of protein amino acid phosphorylation GO:0001934 30 30 1,000 0,01620097 0,08629594 ! skeletal system morphogenesis GO:0048705 31 30 1,000 0,01620097 0,08604724 ! response to temperature stimulus GO:0009266 30 30 1,000 0,01620097 0,08579998 ! vascular process in circulatory system GO:0003018 31 30 1,000 0,01620097 0,08555414 ! blood vessel morphogenesis GO:0048514 84 83 2,000 0,01669385 0,08790504 ! skeletal muscle fiber development GO:0048741 31 31 1,000 0,01724696 0,09055881 ! B cell activation GO:0042113 31 31 1,000 0,01724696 0,09030154 ! positive regulation of phospholipase activity GO:0010518 31 31 1,000 0,01724696 0,09004573 ! regulation of myeloid cell differentiation GO:0045637 32 31 1,000 0,01724696 0,08979136 ! nitrogen compound biosynthetic process GO:0044271 86 85 2,000 0,01778425 0,0923278 ! positive regulation of cell differentiation GO:0045597 87 85 2,000 0,01778425 0,09206845 ! muscle fiber development GO:0048747 32 32 1,000 0,01832102 0,09458163 ! regulation of phospholipase activity GO:0010517 32 32 1,000 0,01832102 0,09431744 ! cell maturation GO:0048469 32 32 1,000 0,01832102 0,09405471 ! regulation of lymphocyte differentiation GO:0045619 32 32 1,000 0,01832102 0,09379345 ! positive regulation of lipase activity GO:0060193 32 32 1,000 0,01832102 0,09353364 ! regulation of anatomical structure morphogenesis GO:0022603 90 86 2,000 0,0183441 0,09339275 ! regulation of neuron differentiation GO:0045664 34 33 1,000 0,01942277 0,09861203 ! regulation of neuron apoptosis GO:0043523 34 33 1,000 0,01942277 0,09834112 ! regulation of synaptic transmission GO:0050804 33 33 1,000 0,01942277 0,09807169 ! male gamete generation GO:0048232 90 88 2,000 0,01949317 0,09815825 GO:0007283|spermatogenesis, ! regulation of angiogenesis GO:0045765 35 34 1,000 0,02055182 0,10320707 ! regulation of bone remodeling GO:0046850 34 34 1,000 0,02055182 0,10292662 ! response to metal ion GO:0010038 34 34 1,000 0,02055182 0,10264768 ! muscle cell differentiation GO:0042692 35 34 1,000 0,02055182 0,10237026 ! regulation of lipid metabolic process GO:0019216 34 34 1,000 0,02055182 0,10209433 ! viral reproduction GO:0016032 34 34 1,000 0,02055182 0,10181988 ! regulation of cyclin-dependent protein kinase activity GO:0000079 35 35 1,000 0,02170777 0,10725848 ! regulation of cell morphogenesis GO:0022604 38 35 1,000 0,02170777 0,10697169 ! regulation of tissue remodeling GO:0034103 35 35 1,000 0,02170777 0,10668643 ! response to inorganic substance GO:0010035 36 36 1,000 0,02289024 0,11219871 ! regulation of mitosis GO:0007088 37 36 1,000 0,02289024 0,1119011 GO:0051783|regulation of nuclear division, ! integrin-mediated signaling pathway GO:0007229 36 36 1,000 0,02289024 0,11160506 ! regulation of transmission of nerve impulse GO:0051969 36 36 1,000 0,02289024 0,11131059 ! regulation of lipase activity GO:0060191 36 36 1,000 0,02289024 0,11101767 ! coagulation GO:0050817 39 36 1,000 0,02289024 0,11072628 GO:0007596|blood coagulation, ! regulation of response to stress GO:0080134 97 94 2,000 0,02317604 0,11181529 ! blood vessel development GO:0001568 95 94 2,000 0,02317604 0,11152334 ! regulation of adenylate cyclase activity GO:0045761 37 37 1,000 0,02409886 0,11566197 GO:0031279|regulation of cyclase activity, GO:0051339|regulation of lyase activity, ! regulation of transcription factor activity GO:0051090 38 37 1,000 0,02409886 0,11536155 GO:0090046|regulation of transcription regulator activity, ! lung development GO:0030324 38 37 1,000 0,02409886 0,11506268 ! DNA damage response, signal transduction GO:0042770 37 37 1,000 0,02409886 0,11476536 ! regulation of Rho protein signal transduction GO:0035023 37 37 1,000 0,02409886 0,11446958 ! adaptive immune response GO:0002250 37 37 1,000 0,02409886 0,11417531 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! vasculature development GO:0001944 97 96 2,000 0,02448235 0,11569481 ! cell-matrix adhesion GO:0007160 39 38 1,000 0,02533324 0,11940963 ! chromosome segregation GO:0007059 38 38 1,000 0,02533324 0,11910502 ! axon guidance GO:0007411 39 38 1,000 0,02533324 0,11880195 ! regulation of neurological system process GO:0031644 38 38 1,000 0,02533324 0,11850042 ! regulation of homeostatic process GO:0032844 38 38 1,000 0,02533324 0,11820042 ! posttranscriptional regulation of gene expression GO:0010608 98 98 2,000 0,02582803 0,12020468 ! regulation of cAMP biosynthetic process GO:0030817 39 39 1,000 0,02659302 0,12345325 ! hemostasis GO:0007599 42 39 1,000 0,02659302 0,12314306 ! positive regulation of protein modification process GO:0031401 39 39 1,000 0,02659302 0,12283443 ! respiratory tube development GO:0030323 40 39 1,000 0,02659302 0,12252735 ! nucleotide-excision repair GO:0006289 40 39 1,000 0,02659302 0,12222179 ! respiratory system development GO:0060541 40 39 1,000 0,02659302 0,12191776 ! developmental maturation GO:0021700 39 39 1,000 0,02659302 0,12161523 ! lymphocyte differentiation GO:0030098 39 39 1,000 0,02659302 0,12131421 ! response to hormone stimulus GO:0009725 102 100 2,000 0,02721304 0,12383614 ! muscle organ development GO:0007517 102 100 2,000 0,02721304 0,12353113 ! hemopoiesis GO:0030097 104 100 2,000 0,02721304 0,12322761 ! regulation of cAMP metabolic process GO:0030814 40 40 1,000 0,02787783 0,12592851 ! myeloid cell differentiation GO:0030099 42 40 1,000 0,02787783 0,12562062 ! regulation of nucleotide biosynthetic process GO:0030808 41 41 1,000 0,02918729 0,13120043 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! regulation of caspase activity GO:0043281 41 41 1,000 0,02918729 0,13088121 ! regulation of cyclic nucleotide metabolic process GO:0030799 42 42 1,000 0,03052105 0,13652985 ! regulation of endopeptidase activity GO:0052548 42 42 1,000 0,03052105 0,13619927 ! protein ubiquitination GO:0016567 43 42 1,000 0,03052105 0,13587028 ! one-carbon metabolic process GO:0006730 42 42 1,000 0,03052105 0,13554289 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 43 43 1,000 0,03187875 0,14123207 ! mitochondrion organization GO:0007005 44 43 1,000 0,03187875 0,14089338 ! homeostasis of number of cells GO:0048872 44 43 1,000 0,03187875 0,14055632 ! regulation of nucleotide metabolic process GO:0006140 43 43 1,000 0,03187875 0,14022086 ! rRNA transcription GO:0009303 5 5 0,000 0,03228773 0,14168165 ! positive regulation of protein ubiquitination GO:0031398 5 5 0,000 0,03228773 0,14134512 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 5 5 0,000 0,03228773 0,14101018 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 5 5 0,000 0,03228773 0,14067682 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! neuron fate specification GO:0048665 5 5 0,000 0,03228773 0,14034504 ! hemoglobin biosynthetic process GO:0042541 5 5 0,000 0,03228773 0,14001481 ! reproductive cellular process GO:0048610 5 5 0,000 0,03228773 0,13968614 ! positive regulation of glucose metabolic process GO:0010907 5 5 0,000 0,03228773 0,139359 ! negative regulation of blood pressure GO:0045776 6 5 0,000 0,03228773 0,1390334 ! prostate gland development GO:0030850 5 5 0,000 0,03228773 0,13870931 ! metencephalon development GO:0022037 5 5 0,000 0,03228773 0,13838673 ! water transport GO:0006833 5 5 0,000 0,03228773 0,13806565 GO:0042044|fluid transport, ! forebrain regionalization GO:0021871 5 5 0,000 0,03228773 0,13774605 ! positive regulation of B cell proliferation GO:0030890 5 5 0,000 0,03228773 0,13742793 ! glycerol metabolic process GO:0006071 5 5 0,000 0,03228773 0,13711128 ! regulation of cellular amine metabolic process GO:0033238 5 5 0,000 0,03228773 0,13679608 GO:0042053|regulation of dopamine metabolic process, GO:0042069|regulation of catecholamine metabolic process, ! meiotic prophase I GO:0007128 5 5 0,000 0,03228773 0,13648233 GO:0051324|prophase, ! cell volume homeostasis GO:0006884 5 5 0,000 0,03228773 0,13617001 ! regulation of epidermal growth factor receptor activity GO:0007176 5 5 0,000 0,03228773 0,13585912 GO:0010469|regulation of receptor activity, ! regulation of long-term neuronal synaptic plasticity GO:0048169 5 5 0,000 0,03228773 0,13554965 ! filopodium assembly GO:0046847 7 5 0,000 0,03228773 0,13524158 GO:0030035|microspike assembly, ! CTP metabolic process GO:0046036 5 5 0,000 0,03228773 0,13493491 GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0006241|CTP biosynthetic process, ! Golgi to endosome transport GO:0006895 5 5 0,000 0,03228773 0,13462963 ! GTP metabolic process GO:0046039 5 5 0,000 0,03228773 0,13432572 ! establishment of tissue polarity GO:0007164 5 5 0,000 0,03228773 0,13402319 ! positive regulation of cell-cell adhesion GO:0022409 5 5 0,000 0,03228773 0,13372201 ! regulation of neurotransmitter secretion GO:0046928 5 5 0,000 0,03228773 0,13342219 GO:0001956|positive regulation of neurotransmitter secretion, ! neurotransmitter uptake GO:0001504 5 5 0,000 0,03228773 0,1331237 ! social behavior GO:0035176 5 5 0,000 0,03228773 0,13282655 ! macrophage chemotaxis GO:0048246 6 5 0,000 0,03228773 0,13253072 ! memory GO:0007613 5 5 0,000 0,03228773 0,13223621 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 5 5 0,000 0,03228773 0,131943 ! membrane hyperpolarization GO:0060081 5 5 0,000 0,03228773 0,1316511 ! response to lipid GO:0033993 5 5 0,000 0,03228773 0,13136047 ! erythrocyte maturation GO:0043249 5 5 0,000 0,03228773 0,13107113 ! hippocampus development GO:0021766 6 5 0,000 0,03228773 0,13078307 ! regulation of carbohydrate biosynthetic process GO:0043255 5 5 0,000 0,03228773 0,13049626 ! glucocorticoid metabolic process GO:0008211 5 5 0,000 0,03228773 0,13021071 ! middle ear morphogenesis GO:0042474 5 5 0,000 0,03228773 0,12992641 ! amyloid precursor protein catabolic process GO:0042987 5 5 0,000 0,03228773 0,12964334 ! mechanosensory behavior GO:0007638 5 5 0,000 0,03228773 0,12936151 ! heart looping GO:0001947 5 5 0,000 0,03228773 0,1290809 ! negative regulation of endocytosis GO:0045806 5 5 0,000 0,03228773 0,1288015 ! response to interferon-gamma GO:0034341 5 5 0,000 0,03228773 0,12852332 ! pseudouridine synthesis GO:0001522 5 5 0,000 0,03228773 0,12824633 ! endocrine pancreas development GO:0031018 5 5 0,000 0,03228773 0,12797053 ! pH reduction GO:0045851 5 5 0,000 0,03228773 0,12769591 GO:0051452|intracellular pH reduction, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 5 5 0,000 0,03228773 0,12742247 ! lipopolysaccharide metabolic process GO:0008653 5 5 0,000 0,03228773 0,1271502 ! positive regulation of chemokine biosynthetic process GO:0045080 5 5 0,000 0,03228773 0,12687909 ! sphingoid biosynthetic process GO:0046520 5 5 0,000 0,03228773 0,12660914 GO:0046513|ceramide biosynthetic process, ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 5 5 0,000 0,03228773 0,12634033 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! thymic T cell selection GO:0045061 5 5 0,000 0,03228773 0,12607266 ! photoreceptor cell maintenance GO:0045494 5 5 0,000 0,03228773 0,12580612 ! adrenal gland development GO:0030325 5 5 0,000 0,03228773 0,12554071 ! regulation of cardiac muscle hypertrophy GO:0010611 5 5 0,000 0,03228773 0,12527641 GO:0010612|regulation of cardiac muscle adaptation, GO:0014743|regulation of muscle hypertrophy, GO:0043502|regulation of muscle adaptation, ! melanocyte differentiation GO:0030318 5 5 0,000 0,03228773 0,12501322 GO:0050931|pigment cell differentiation, ! ovulation GO:0030728 5 5 0,000 0,03228773 0,12475114 ! astrocyte differentiation GO:0048708 5 5 0,000 0,03228773 0,12449016 ! mitochondrial respiratory chain complex assembly GO:0033108 5 5 0,000 0,03228773 0,12423026 GO:0032981|mitochondrial respiratory chain complex I assembly, GO:0010257|NADH dehydrogenase complex assembly, ! pituitary gland development GO:0021983 5 5 0,000 0,03228773 0,12397145 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 5 5 0,000 0,03228773 0,12371371 GO:0033135|regulation of peptidyl-serine phosphorylation, ! tyrosine metabolic process GO:0006570 5 5 0,000 0,03228773 0,12345704 ! cytoskeletal anchoring at plasma membrane GO:0007016 6 5 0,000 0,03228773 0,12320144 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 5 5 0,000 0,03228773 0,12294689 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, GO:0009164|nucleoside catabolic process, ! microtubule nucleation GO:0007020 5 5 0,000 0,03228773 0,12269339 ! regulation of interleukin-6 biosynthetic process GO:0045408 5 5 0,000 0,03228773 0,12244094 ! regulation of interleukin-8 biosynthetic process GO:0045414 5 5 0,000 0,03228773 0,12218952 ! indolalkylamine metabolic process GO:0006586 5 5 0,000 0,03228773 0,12193913 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! muscle cell migration GO:0014812 5 5 0,000 0,03228773 0,12168976 ! phasic smooth muscle contraction GO:0014821 5 5 0,000 0,03228773 0,12144142 ! central nervous system neuron axonogenesis GO:0021955 6 5 0,000 0,03228773 0,12119408 GO:0021952|central nervous system projection neuron axonogenesis, ! sister chromatid cohesion GO:0007062 5 5 0,000 0,03228773 0,12094775 ! response to ATP GO:0033198 5 5 0,000 0,03228773 0,12070242 ! regulation of type I interferon production GO:0032479 5 5 0,000 0,03228773 0,12045809 ! regulation of appetite GO:0032098 5 5 0,000 0,03228773 0,12021474 GO:0032095|regulation of response to food, ! vesicle fusion GO:0006906 5 5 0,000 0,03228773 0,11997237 ! paraxial mesoderm development GO:0048339 5 5 0,000 0,03228773 0,11973098 ! regulation of the force of heart contraction GO:0002026 5 5 0,000 0,03228773 0,11949055 ! maintenance of protein location in nucleus GO:0051457 5 5 0,000 0,03228773 0,11925109 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,03228773 0,11901259 ! neurotransmitter biosynthetic process GO:0042136 6 5 0,000 0,03228773 0,11877504 ! fear response GO:0042596 5 5 0,000 0,03228773 0,11853844 ! lens development in camera-type eye GO:0002088 5 5 0,000 0,03228773 0,11830277 ! retinol metabolic process GO:0042572 5 5 0,000 0,03228773 0,11806805 ! corticosteroid receptor signaling pathway GO:0031958 5 5 0,000 0,03228773 0,11783425 GO:0042921|glucocorticoid receptor signaling pathway, ! temperature homeostasis GO:0001659 5 5 0,000 0,03228773 0,11760137 ! positive regulation of exocytosis GO:0045921 6 5 0,000 0,03228773 0,11736942 ! parturition GO:0007567 5 5 0,000 0,03228773 0,11713838 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,03228773 0,11690824 ! regulation of vascular endothelial growth factor production GO:0010574 5 5 0,000 0,03228773 0,11667901 ! Schwann cell differentiation GO:0014037 5 5 0,000 0,03228773 0,11645068 ! acyl-CoA metabolic process GO:0006637 5 5 0,000 0,03228773 0,11622323 ! wound healing, spreading of epidermal cells GO:0035313 5 5 0,000 0,03228773 0,11599668 ! protein heterooligomerization GO:0051291 5 5 0,000 0,03228773 0,115771 ! regulation of gliogenesis GO:0014013 5 5 0,000 0,03228773 0,1155462 GO:0045685|regulation of glial cell differentiation, ! positive regulation of peptide secretion GO:0002793 5 5 0,000 0,03228773 0,11532228 ! response to UV-B GO:0010224 5 5 0,000 0,03228773 0,11509922 ! oligodendrocyte development GO:0014003 5 5 0,000 0,03228773 0,11487702 ! hyaluronan metabolic process GO:0030212 5 5 0,000 0,03228773 0,11465567 ! activated T cell proliferation GO:0050798 5 5 0,000 0,03228773 0,11443518 ! interaction with symbiont GO:0051702 5 5 0,000 0,03228773 0,11421554 ! cellular extravasation GO:0045123 5 5 0,000 0,03228773 0,11399673 ! positive regulation of axonogenesis GO:0050772 5 5 0,000 0,03228773 0,11377877 ! peptidyl-asparagine modification GO:0018196 5 5 0,000 0,03228773 0,11356163 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! positive regulation of phagocytosis GO:0050766 5 5 0,000 0,03228773 0,11334532 ! regulation of insulin receptor signaling pathway GO:0046626 5 5 0,000 0,03228773 0,11312984 ! antigen processing and presentation of exogenous antigen GO:0019884 5 5 0,000 0,03228773 0,11291517 ! response to amine stimulus GO:0014075 5 5 0,000 0,03228773 0,11270132 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 5 5 0,000 0,03228773 0,11248827 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 5 5 0,000 0,03228773 0,11227603 ! synaptic vesicle exocytosis GO:0016079 6 5 0,000 0,03228773 0,11206459 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 5 5 0,000 0,03228773 0,11185394 ! glycosylceramide metabolic process GO:0006677 5 5 0,000 0,03228773 0,11164408 ! neuron recognition GO:0008038 5 5 0,000 0,03228773 0,11143501 ! negative regulation of focal adhesion formation GO:0051895 6 5 0,000 0,03228773 0,11122672 ! decidualization GO:0046697 5 5 0,000 0,03228773 0,11101921 ! hair follicle maturation GO:0048820 5 5 0,000 0,03228773 0,11081247 ! phosphatidylinositol biosynthetic process GO:0006661 5 5 0,000 0,03228773 0,1106065 ! regulation of mitochondrial membrane potential GO:0051881 5 5 0,000 0,03228773 0,11040129 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 0,03228773 0,11019684 GO:0009155|purine deoxyribonucleotide catabolic process, ! regulation of interleukin-12 production GO:0032655 5 5 0,000 0,03228773 0,10999315 ! positive regulation of interleukin-6 production GO:0032755 5 5 0,000 0,03228773 0,10979021 ! positive regulation of monooxygenase activity GO:0032770 5 5 0,000 0,03228773 0,10958802 ! postreplication repair GO:0006301 5 5 0,000 0,03228773 0,10938657 ! spinal cord motor neuron differentiation GO:0021522 5 5 0,000 0,03228773 0,10918586 GO:0021517|ventral spinal cord development, ! cellular pigmentation GO:0033059 5 5 0,000 0,03228773 0,10898589 ! histone methylation GO:0016571 5 5 0,000 0,03228773 0,10878665 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,03228773 0,10858813 ! positive regulation of immunoglobulin mediated immune response GO:0002891 5 5 0,000 0,03228773 0,10839034 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of interferon-gamma production GO:0032729 5 5 0,000 0,03228773 0,10819326 ! negative regulation of tumor necrosis factor production GO:0032720 5 5 0,000 0,03228773 0,10799691 ! intracellular cholesterol transport GO:0032367 5 5 0,000 0,03228773 0,10780126 GO:0032366|intracellular sterol transport, ! regulation of mast cell activation GO:0033003 5 5 0,000 0,03228773 0,10760632 ! morphogenesis of a polarized epithelium GO:0001738 5 5 0,000 0,03228773 0,10741208 ! regulation of hormone metabolic process GO:0032350 5 5 0,000 0,03228773 0,10721855 ! regulation of transcription from RNA polymerase III promoter GO:0006359 5 5 0,000 0,03228773 0,10702571 ! regulation of inflammatory response to antigenic stimulus GO:0002861 5 5 0,000 0,03228773 0,10683356 ! sterol catabolic process GO:0016127 5 5 0,000 0,03228773 0,10664211 GO:0006707|cholesterol catabolic process, ! negative regulation of oxidoreductase activity GO:0051354 5 5 0,000 0,03228773 0,10645133 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 5 5 0,000 0,03228773 0,10626124 ! detection of biotic stimulus GO:0009595 5 5 0,000 0,03228773 0,10607183 ! regulation of immune response to tumor cell GO:0002837 5 5 0,000 0,03228773 0,10588309 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 5 5 0,000 0,03228773 0,10569502 ! zymogen activation GO:0031638 5 5 0,000 0,03228773 0,10550762 ! positive regulation of interleukin-1 beta secretion GO:0050718 5 5 0,000 0,03228773 0,10532088 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 5 5 0,000 0,03228773 0,1051348 GO:0002820|negative regulation of adaptive immune response, ! cellular response to nutrient GO:0031670 5 5 0,000 0,03228773 0,10494937 ! peptidyl-lysine modification GO:0018205 5 5 0,000 0,03228773 0,1047646 ! peptidyl-histidine modification GO:0018202 5 5 0,000 0,03228773 0,10458048 ! nucleosome positioning GO:0016584 5 5 0,000 0,03228773 0,10439701 ! regulation of isotype switching GO:0045191 5 5 0,000 0,03228773 0,10421418 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 5 5 0,000 0,03228773 0,10403198 ! negative regulation of neurological system process GO:0031645 5 5 0,000 0,03228773 0,10385043 ! regulation of myoblast differentiation GO:0045661 5 5 0,000 0,03228773 0,1036695 ! glutathione biosynthetic process GO:0006750 5 5 0,000 0,03228773 0,10348921 ! NADPH regeneration GO:0006740 5 5 0,000 0,03228773 0,10330954 GO:0006098|pentose-phosphate shunt, ! positive regulation of erythrocyte differentiation GO:0045648 5 5 0,000 0,03228773 0,10313049 ! positive regulation of epidermis development GO:0045684 5 5 0,000 0,03228773 0,10295207 ! positive regulation of leukocyte chemotaxis GO:0002690 5 5 0,000 0,03228773 0,10277426 GO:0002688|regulation of leukocyte chemotaxis, ! musculoskeletal movement GO:0050881 5 5 0,000 0,03228773 0,10259706 GO:0050879|multicellular organismal movement, ! neuromuscular process controlling posture GO:0050884 5 5 0,000 0,03228773 0,10242047 ! sarcomere organization GO:0045214 5 5 0,000 0,03228773 0,10224449 ! regulation of epidermal cell differentiation GO:0045604 5 5 0,000 0,03228773 0,10206912 ! activation of NF-kappaB-inducing kinase activity GO:0007250 5 5 0,000 0,03228773 0,10189434 ! negative regulation of glucose transport GO:0010829 5 5 0,000 0,03228773 0,10172016 GO:0046325|negative regulation of glucose import, ! positive regulation of T-helper cell differentiation GO:0045624 5 5 0,000 0,03228773 0,10154658 GO:0045622|regulation of T-helper cell differentiation, ! oocyte differentiation GO:0009994 5 5 0,000 0,03228773 0,10137359 GO:0048599|oocyte development, ! dopamine biosynthetic process GO:0042416 5 5 0,000 0,03228773 0,10120118 ! regulation of protein homodimerization activity GO:0043496 6 5 0,000 0,03228773 0,10102936 ! spleen development GO:0048536 5 5 0,000 0,03228773 0,10085813 ! male genitalia development GO:0030539 5 5 0,000 0,03228773 0,10068747 ! nicotinamide nucleotide biosynthetic process GO:0019359 5 5 0,000 0,03228773 0,10051739 ! quaternary ammonium group transport GO:0015697 5 5 0,000 0,03228773 0,10034788 ! thyroid hormone metabolic process GO:0042403 5 5 0,000 0,03228773 0,10017895 ! leukocyte mediated cytotoxicity GO:0001909 5 5 0,000 0,03228773 0,10001058 ! removal of superoxide radicals GO:0019430 6 5 0,000 0,03228773 0,09984278 ! myeloid cell homeostasis GO:0002262 5 5 0,000 0,03228773 0,09967554 ! regulation of fatty acid oxidation GO:0046320 5 5 0,000 0,03228773 0,09950885 ! regulation of Rac protein signal transduction GO:0035020 5 5 0,000 0,03228773 0,09934273 ! ATP catabolic process GO:0006200 5 5 0,000 0,03228773 0,09917716 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,03228773 0,09901214 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 5 5 0,000 0,03228773 0,09884767 ! blastocyst formation GO:0001825 5 5 0,000 0,03228773 0,09868374 ! regulation of fibrinolysis GO:0051917 5 5 0,000 0,03228773 0,09852036 ! embryonic gut development GO:0048566 5 5 0,000 0,03228773 0,09835751 ! negative regulation of organic acid transport GO:0032891 5 5 0,000 0,03228773 0,09819521 ! activation of innate immune response GO:0002218 5 5 0,000 0,03228773 0,09803343 GO:0002758|innate immune response-activating signal transduction, ! catecholamine transport GO:0051937 5 5 0,000 0,03228773 0,0978722 ! negative regulation of blood vessel endothelial cell migration GO:0043537 5 5 0,000 0,03228773 0,09771149 ! regulation of NF-kappaB import into nucleus GO:0042345 5 5 0,000 0,03228773 0,0975513 ! muscle adaptation GO:0043500 5 5 0,000 0,03228773 0,09739164 ! positive regulation of actin filament bundle formation GO:0032233 5 5 0,000 0,03228773 0,09723251 ! embryonic heart tube development GO:0035050 5 5 0,000 0,03228773 0,09707389 ! cardiac cell differentiation GO:0035051 6 5 0,000 0,03228773 0,09691579 ! positive regulation of homeostatic process GO:0032846 5 5 0,000 0,03228773 0,0967582 ! defense response to fungus GO:0050832 5 5 0,000 0,03228773 0,09660113 ! prepulse inhibition GO:0060134 5 5 0,000 0,03228773 0,09644456 ! B cell receptor signaling pathway GO:0050853 5 5 0,000 0,03228773 0,0962885 ! positive regulation of smooth muscle contraction GO:0045987 5 5 0,000 0,03228773 0,09613295 ! response to nicotine GO:0035094 5 5 0,000 0,03228773 0,0959779 ! establishment of cell polarity GO:0030010 5 5 0,000 0,03228773 0,09582334 ! mitochondrion localization GO:0051646 5 5 0,000 0,03228773 0,09566928 ! nucleus localization GO:0051647 5 5 0,000 0,03228773 0,09551572 ! regulation of synapse structure and activity GO:0050803 5 5 0,000 0,03228773 0,09536265 ! protein import into nucleus GO:0006606 44 44 1,000 0,03326004 0,09807719 ! homophilic cell adhesion GO:0007156 45 45 1,000 0,03466455 0,10205554 ! nuclear import GO:0051170 45 45 1,000 0,03466455 0,10189278 ! Wnt receptor signaling pathway GO:0016055 46 45 1,000 0,03466455 0,10173053 ! cyclic-nucleotide-mediated signaling GO:0019935 46 46 1,000 0,03609195 0,10575114 ! regulation of peptidase activity GO:0052547 46 46 1,000 0,03609195 0,10558329 ! cellular response to hormone stimulus GO:0032870 48 46 1,000 0,03609195 0,10541596 ! regulation of membrane potential GO:0042391 46 46 1,000 0,03609195 0,10524916 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 47 47 1,000 0,03754189 0,10930444 ! axon extension GO:0048675 7 6 0,000 0,03862185 0,11227141 ! oligosaccharide biosynthetic process GO:0009312 6 6 0,000 0,03862185 0,1120946 ! N-terminal protein amino acid modification GO:0031365 6 6 0,000 0,03862185 0,11191835 GO:0018409|peptide or protein amino-terminal blocking, ! tRNA modification GO:0006400 6 6 0,000 0,03862185 0,11174266 ! somatic diversification of immune receptors via somatic mutation GO:0002566 6 6 0,000 0,03862185 0,11156751 GO:0016446|somatic hypermutation of immunoglobulin genes, ! 'de novo' posttranslational protein folding GO:0051084 6 6 0,000 0,03862185 0,11139291 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 6 6 0,000 0,03862185 0,11121886 ! negative regulation of cellular catabolic process GO:0031330 6 6 0,000 0,03862185 0,11104535 ! virus-host interaction GO:0019048 6 6 0,000 0,03862185 0,11087239 ! regulation of S phase GO:0033261 6 6 0,000 0,03862185 0,11069996 ! myotube differentiation GO:0014902 6 6 0,000 0,03862185 0,11052806 ! regulation of B cell proliferation GO:0030888 6 6 0,000 0,03862185 0,1103567 ! bone remodeling GO:0046849 6 6 0,000 0,03862185 0,11018587 ! N-glycan processing GO:0006491 6 6 0,000 0,03862185 0,11001557 ! glycosaminoglycan catabolic process GO:0006027 6 6 0,000 0,03862185 0,10984579 ! negative regulation of JAK-STAT cascade GO:0046426 6 6 0,000 0,03862185 0,10967654 ! retina development in camera-type eye GO:0060041 6 6 0,000 0,03862185 0,1095078 ! RNA methylation GO:0001510 6 6 0,000 0,03862185 0,10933959 ! regulation of activated T cell proliferation GO:0046006 6 6 0,000 0,03862185 0,10917189 ! artery development GO:0060840 6 6 0,000 0,03862185 0,1090047 GO:0048844|artery morphogenesis, ! positive regulation of neurotransmitter transport GO:0051590 6 6 0,000 0,03862185 0,10883803 ! bile acid metabolic process GO:0008206 6 6 0,000 0,03862185 0,10867187 ! androgen metabolic process GO:0008209 6 6 0,000 0,03862185 0,10850621 ! estrogen metabolic process GO:0008210 6 6 0,000 0,03862185 0,10834105 ! limbic system development GO:0021761 7 6 0,000 0,03862185 0,1081764 ! positive regulation of heart contraction GO:0045823 6 6 0,000 0,03862185 0,10801225 ! positive regulation of gene expression, epigenetic GO:0045815 6 6 0,000 0,03862185 0,10784859 ! pathogenesis GO:0009405 6 6 0,000 0,03862185 0,10768543 ! negative regulation of protein amino acid phosphorylation GO:0001933 6 6 0,000 0,03862185 0,10752277 ! positive regulation of cell growth GO:0030307 6 6 0,000 0,03862185 0,10736059 ! ribonucleoside triphosphate catabolic process GO:0009203 6 6 0,000 0,03862185 0,1071989 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! regulation of chemokine biosynthetic process GO:0045073 6 6 0,000 0,03862185 0,1070377 ! nerve growth factor receptor signaling pathway GO:0048011 6 6 0,000 0,03862185 0,10687698 ! inositol phosphate-mediated signaling GO:0048016 6 6 0,000 0,03862185 0,10671675 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 6 6 0,000 0,03862185 0,10655699 ! arginine metabolic process GO:0006525 6 6 0,000 0,03862185 0,10639772 GO:0006527|arginine catabolic process, ! regulation of catecholamine secretion GO:0050433 6 6 0,000 0,03862185 0,10623891 ! oligodendrocyte differentiation GO:0048709 6 6 0,000 0,03862185 0,10608058 ! glutamate catabolic process GO:0006538 7 6 0,000 0,03862185 0,10592273 ! telomere maintenance via telomerase GO:0007004 6 6 0,000 0,03862185 0,10576534 GO:0010833|telomere maintenance via telomere lengthening, ! L-phenylalanine metabolic process GO:0006558 6 6 0,000 0,03862185 0,10560842 GO:0006559|L-phenylalanine catabolic process, ! glucan biosynthetic process GO:0009250 6 6 0,000 0,03862185 0,10545196 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 6 6 0,000 0,03862185 0,10529596 ! focal adhesion formation GO:0048041 7 6 0,000 0,03862185 0,10514043 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 0,03862185 0,10498536 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 6 6 0,000 0,03862185 0,10483074 ! negative regulation of endothelial cell migration GO:0010596 6 6 0,000 0,03862185 0,10467658 ! regulation of heart rate GO:0002027 6 6 0,000 0,03862185 0,10452287 ! lipid digestion GO:0044241 6 6 0,000 0,03862185 0,10436961 ! asymmetric protein localization GO:0008105 6 6 0,000 0,03862185 0,1042168 ! retrograde transport, endosome to Golgi GO:0042147 6 6 0,000 0,03862185 0,10406443 ! phagocytosis, engulfment GO:0006911 6 6 0,000 0,03862185 0,10391251 ! Rac protein signal transduction GO:0016601 6 6 0,000 0,03862185 0,10376104 ! regulation of calcium ion transport into cytosol GO:0010522 6 6 0,000 0,03862185 0,10361 ! ruffle organization GO:0031529 6 6 0,000 0,03862185 0,10345941 ! peptidyl-serine phosphorylation GO:0018105 6 6 0,000 0,03862185 0,10330925 ! preassembly of GPI anchor in ER membrane GO:0016254 6 6 0,000 0,03862185 0,10315952 ! retinoic acid metabolic process GO:0042573 6 6 0,000 0,03862185 0,10301023 ! neutral amino acid transport GO:0015804 6 6 0,000 0,03862185 0,10286138 ! L-amino acid transport GO:0015807 6 6 0,000 0,03862185 0,10271295 ! bone mineralization GO:0030282 6 6 0,000 0,03862185 0,10256495 GO:0031214|biomineral formation, ! rRNA modification GO:0000154 6 6 0,000 0,03862185 0,10241737 ! negative regulation of ossification GO:0030279 6 6 0,000 0,03862185 0,10227022 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 6 6 0,000 0,03862185 0,10212349 GO:0002717|positive regulation of natural killer cell mediated immunity, GO:0002715|regulation of natural killer cell mediated immunity, GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 7 6 0,000 0,03862185 0,10197718 ! purine base biosynthetic process GO:0009113 6 6 0,000 0,03862185 0,10183129 ! negative regulation of axonogenesis GO:0050771 7 6 0,000 0,03862185 0,10168582 ! regulation of phagocytosis GO:0050764 6 6 0,000 0,03862185 0,10154076 ! regulation of organ growth GO:0046620 6 6 0,000 0,03862185 0,10139611 ! regulation of circadian rhythm GO:0042752 6 6 0,000 0,03862185 0,10125188 ! positive regulation of T cell mediated immunity GO:0002711 6 6 0,000 0,03862185 0,10110806 ! response to dsRNA GO:0043331 6 6 0,000 0,03862185 0,10096464 ! DNA unwinding during replication GO:0006268 6 6 0,000 0,03862185 0,10082163 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 6 6 0,000 0,03862185 0,10067903 GO:0009147|pyrimidine nucleoside triphosphate metabolic process, ! genitalia development GO:0048806 6 6 0,000 0,03862185 0,10053682 ! sphingomyelin metabolic process GO:0006684 6 6 0,000 0,03862185 0,10039502 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 6 6 0,000 0,03862185 0,10025362 ! positive regulation of B cell differentiation GO:0045579 6 6 0,000 0,03862185 0,10011262 ! regulation of focal adhesion formation GO:0051893 7 6 0,000 0,03862185 0,09997201 ! respiratory chain complex IV assembly GO:0008535 6 6 0,000 0,03862185 0,0998318 ! erythrocyte development GO:0048821 6 6 0,000 0,03862185 0,09969198 ! renal water homeostasis GO:0003091 6 6 0,000 0,03862185 0,09955255 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 6 6 0,000 0,03862185 0,09941351 GO:0043372|positive regulation of CD4-positive, alpha beta T cell differentiation, ! ribosomal large subunit biogenesis GO:0042273 6 6 0,000 0,03862185 0,09927486 ! regulation of Rho GTPase activity GO:0032319 6 6 0,000 0,03862185 0,09913659 ! ribosome assembly GO:0042255 6 6 0,000 0,03862185 0,09899871 ! positive regulation of Ras GTPase activity GO:0032320 6 6 0,000 0,03862185 0,09886121 ! diencephalon development GO:0021536 6 6 0,000 0,03862185 0,09872409 ! fucose catabolic process GO:0019317 6 6 0,000 0,03862185 0,09858736 GO:0042355|L-fucose catabolic process, ! protein sumoylation GO:0016925 6 6 0,000 0,03862185 0,098451 ! regulation of lipid transport GO:0032368 6 6 0,000 0,03862185 0,09831502 ! regulation of cell division GO:0051302 6 6 0,000 0,03862185 0,09817941 ! positive regulation of interleukin-1 secretion GO:0050716 6 6 0,000 0,03862185 0,09804418 ! cellular metabolic compound salvage GO:0043094 6 6 0,000 0,03862185 0,09790931 ! regulation of T-helper 2 type immune response GO:0002828 6 6 0,000 0,03862185 0,09777482 ! salivary gland morphogenesis GO:0007435 6 6 0,000 0,03862185 0,0976407 ! neuroblast proliferation GO:0007405 6 6 0,000 0,03862185 0,09750695 ! regulation of interleukin-1 beta secretion GO:0050706 6 6 0,000 0,03862185 0,09737356 ! nitric oxide mediated signal transduction GO:0007263 6 6 0,000 0,03862185 0,09724054 ! regulation of glucose transport GO:0010827 6 6 0,000 0,03862185 0,09710787 GO:0046324|regulation of glucose import, ! intestinal absorption GO:0050892 6 6 0,000 0,03862185 0,09697557 ! methionine biosynthetic process GO:0009086 6 6 0,000 0,03862185 0,09684364 ! glutamine family amino acid biosynthetic process GO:0009084 6 6 0,000 0,03862185 0,09671205 ! serine family amino acid biosynthetic process GO:0009070 6 6 0,000 0,03862185 0,09658083 ! thymus development GO:0048538 6 6 0,000 0,03862185 0,09644996 ! lymph node development GO:0048535 6 6 0,000 0,03862185 0,09631945 ! organic cation transport GO:0015695 6 6 0,000 0,03862185 0,09618929 ! negative regulation of BMP signaling pathway GO:0030514 6 6 0,000 0,03862185 0,09605948 ! regulation of RNA splicing GO:0043484 6 6 0,000 0,03862185 0,09593002 ! regulation of cellular carbohydrate catabolic process GO:0043471 6 6 0,000 0,03862185 0,0958009 GO:0043470|regulation of carbohydrate catabolic process, GO:0006110|regulation of glycolysis, ! positive regulation of JNK cascade GO:0046330 7 6 0,000 0,03862185 0,09567214 ! sperm-egg recognition GO:0035036 7 6 0,000 0,03862185 0,09554372 GO:0007339|binding of sperm to zona pellucida, ! germ cell migration GO:0008354 6 6 0,000 0,03862185 0,09541565 ! establishment or maintenance of apical/basal cell polarity GO:0035088 6 6 0,000 0,03862185 0,09528791 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 6 6 0,000 0,03862185 0,09516052 ! alditol metabolic process GO:0019400 6 6 0,000 0,03862185 0,09503347 ! regulation of synaptic transmission, GABAergic GO:0032228 6 6 0,000 0,03862185 0,09490676 ! regulation of amino acid transport GO:0051955 6 6 0,000 0,03862185 0,09478039 ! maternal placenta development GO:0001893 6 6 0,000 0,03862185 0,09465435 ! regulation of embryonic development GO:0045995 6 6 0,000 0,03862185 0,09452865 ! negative regulation of immune effector process GO:0002698 6 6 0,000 0,03862185 0,09440328 ! regulation of cell cycle process GO:0010564 50 48 1,000 0,03901403 0,09523557 ! protein localization in nucleus GO:0034504 48 48 1,000 0,03901403 0,0951096 ! leukocyte differentiation GO:0002521 50 49 1,000 0,04050803 0,09862126 ! gland development GO:0048732 51 49 1,000 0,04050803 0,09849115 ! skeletal muscle tissue development GO:0007519 50 49 1,000 0,04050803 0,09836139 GO:0060538|skeletal muscle organ development, ! T cell activation GO:0042110 51 50 1,000 0,04202355 0,1019071 ! protein modification by small protein conjugation GO:0032446 52 51 1,000 0,04356026 0,10549483 ! respiratory burst GO:0045730 7 7 0,000 0,04491542 0,10863402 ! negative regulation of cell projection organization GO:0031345 8 7 0,000 0,04491542 0,10849165 ! positive regulation of blood pressure GO:0045777 7 7 0,000 0,04491542 0,10834964 ! positive regulation of cellular catabolic process GO:0031331 7 7 0,000 0,04491542 0,10820801 ! pteridine and derivative biosynthetic process GO:0042559 7 7 0,000 0,04491542 0,10806674 ! regulation of chemokine production GO:0032642 7 7 0,000 0,04491542 0,10792585 ! double-strand break repair via homologous recombination GO:0000724 7 7 0,000 0,04491542 0,10778532 GO:0000725|recombinational repair, ! positive regulation of GTPase activity GO:0043547 7 7 0,000 0,04491542 0,10764516 ! SMAD protein nuclear translocation GO:0007184 7 7 0,000 0,04491542 0,10750536 ! cellular protein complex disassembly GO:0043624 8 7 0,000 0,04491542 0,10736592 GO:0043241|protein complex disassembly, ! hair follicle morphogenesis GO:0031069 7 7 0,000 0,04491542 0,10722685 ! gene silencing by RNA GO:0031047 7 7 0,000 0,04491542 0,10708813 ! regulation of receptor-mediated endocytosis GO:0048259 7 7 0,000 0,04491542 0,10694978 ! regulation of neurotransmitter transport GO:0051588 7 7 0,000 0,04491542 0,10681178 ! keratinocyte proliferation GO:0043616 7 7 0,000 0,04491542 0,10667413 ! negative regulation of muscle cell differentiation GO:0051148 7 7 0,000 0,04491542 0,10653684 ! visual behavior GO:0007632 7 7 0,000 0,04491542 0,1063999 GO:0008542|visual learning, ! startle response GO:0001964 7 7 0,000 0,04491542 0,10626332 ! amyloid precursor protein metabolic process GO:0042982 7 7 0,000 0,04491542 0,10612708 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 8 7 0,000 0,04491542 0,1059912 ! positive regulation of lipid metabolic process GO:0045834 7 7 0,000 0,04491542 0,10585566 ! negative regulation of lipid metabolic process GO:0045833 7 7 0,000 0,04491542 0,10572047 ! regulation of interferon-gamma biosynthetic process GO:0045072 7 7 0,000 0,04491542 0,10558562 ! endothelial cell differentiation GO:0045446 7 7 0,000 0,04491542 0,10545112 ! negative regulation of striated muscle development GO:0045843 7 7 0,000 0,04491542 0,10531695 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 7 7 0,000 0,04491542 0,10518313 ! digestive system development GO:0055123 7 7 0,000 0,04491542 0,10504965 GO:0048546|digestive tract morphogenesis, GO:0048547|gut morphogenesis, ! hemoglobin metabolic process GO:0020027 7 7 0,000 0,04491542 0,10491651 ! regulation of exit from mitosis GO:0007096 7 7 0,000 0,04491542 0,1047837 ! protein targeting to ER GO:0045047 8 7 0,000 0,04491542 0,10465123 ! cell differentiation in spinal cord GO:0021515 7 7 0,000 0,04491542 0,1045191 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 7 7 0,000 0,04491542 0,1043873 ! endoderm development GO:0007492 7 7 0,000 0,04491542 0,10425583 ! regulation of defense response to virus GO:0050688 7 7 0,000 0,04491542 0,10412469 ! glycolipid biosynthetic process GO:0009247 7 7 0,000 0,04491542 0,10399388 GO:0006688|glycosphingolipid biosynthetic process, ! response to hexose stimulus GO:0009746 7 7 0,000 0,04491542 0,1038634 GO:0034284|response to monosaccharide stimulus, GO:0009749|response to glucose stimulus, ! membrane protein ectodomain proteolysis GO:0006509 7 7 0,000 0,04491542 0,10373324 GO:0033619|membrane protein proteolysis, ! positive regulation of survival gene product expression GO:0045885 7 7 0,000 0,04491542 0,10360341 ! regulation of skeletal muscle fiber development GO:0048742 7 7 0,000 0,04491542 0,10347391 ! cardiac muscle tissue development GO:0048738 7 7 0,000 0,04491542 0,10334473 ! nucleotide-sugar metabolic process GO:0009225 7 7 0,000 0,04491542 0,10321587 ! complement activation, alternative pathway GO:0006957 7 7 0,000 0,04491542 0,10308733 ! arachidonic acid secretion GO:0050482 7 7 0,000 0,04491542 0,10295911 GO:0032309|icosanoid secretion, ! polyamine biosynthetic process GO:0006596 7 7 0,000 0,04491542 0,10283121 ! UV protection GO:0009650 7 7 0,000 0,04491542 0,10270363 ! myofibril assembly GO:0030239 7 7 0,000 0,04491542 0,10257636 GO:0055002|striated muscle cell development, ! positive regulation of carbohydrate metabolic process GO:0045913 7 7 0,000 0,04491542 0,10244941 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! positive regulation of muscle contraction GO:0045933 7 7 0,000 0,04491542 0,10232278 ! negative regulation of muscle contraction GO:0045932 7 7 0,000 0,04491542 0,10219645 ! chondroitin sulfate biosynthetic process GO:0030206 7 7 0,000 0,04491542 0,10207044 GO:0030204|chondroitin sulfate metabolic process, ! regulation of exocytosis GO:0017157 8 7 0,000 0,04491542 0,10194474 ! phosphatidylcholine biosynthetic process GO:0006656 7 7 0,000 0,04491542 0,10181934 ! heparan sulfate proteoglycan metabolic process GO:0030201 7 7 0,000 0,04491542 0,10169426 GO:0015012|heparan sulfate proteoglycan biosynthetic process, ! stem cell development GO:0048864 7 7 0,000 0,04491542 0,10156948 GO:0019827|stem cell maintenance, ! alpha-beta T cell differentiation GO:0046632 7 7 0,000 0,04491542 0,10144501 ! negative regulation of myeloid leukocyte differentiation GO:0002762 7 7 0,000 0,04491542 0,10132084 ! NLS-bearing substrate import into nucleus GO:0006607 7 7 0,000 0,04491542 0,10119698 ! axon cargo transport GO:0008088 7 7 0,000 0,04491542 0,10107341 ! eating behavior GO:0042755 7 7 0,000 0,04491542 0,10095015 ! RNA-dependent DNA replication GO:0006278 7 7 0,000 0,04491542 0,10082719 ! purine nucleoside triphosphate catabolic process GO:0009146 7 7 0,000 0,04491542 0,10070453 ! regulation of interleukin-8 production GO:0032677 7 7 0,000 0,04491542 0,10058217 ! purine ribonucleotide catabolic process GO:0009154 7 7 0,000 0,04491542 0,1004601 ! ribosomal small subunit biogenesis GO:0042274 7 7 0,000 0,04491542 0,10033833 ! cranial nerve development GO:0021545 7 7 0,000 0,04491542 0,10021686 ! protein import into peroxisome matrix GO:0016558 7 7 0,000 0,04491542 0,10009568 ! induction of an organ GO:0001759 7 7 0,000 0,04491542 0,09997479 ! leukocyte activation during immune response GO:0002366 7 7 0,000 0,04491542 0,09985419 GO:0002263|cell activation during immune response, ! response to estradiol stimulus GO:0032355 7 7 0,000 0,04491542 0,09973389 ! autonomic nervous system development GO:0048483 7 7 0,000 0,04491542 0,09961387 ! intracellular lipid transport GO:0032365 7 7 0,000 0,04491542 0,09949414 ! detection of chemical stimulus GO:0009593 8 7 0,000 0,04491542 0,0993747 ! negative regulation of cytokine secretion GO:0050710 7 7 0,000 0,04491542 0,09925555 ! regulation of interleukin-1 secretion GO:0050704 7 7 0,000 0,04491542 0,09913668 ! natural killer cell activation GO:0030101 7 7 0,000 0,04491542 0,09901809 ! NADP metabolic process GO:0006739 7 7 0,000 0,04491542 0,09889979 ! neuromuscular synaptic transmission GO:0007274 7 7 0,000 0,04491542 0,09878177 ! ubiquinone metabolic process GO:0006743 7 7 0,000 0,04491542 0,09866404 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, GO:0042375|quinone cofactor metabolic process, ! positive regulation of acute inflammatory response GO:0002675 7 7 0,000 0,04491542 0,09854658 ! regulation of osteoclast differentiation GO:0045670 7 7 0,000 0,04491542 0,0984294 ! negative regulation of cell-substrate adhesion GO:0010812 8 7 0,000 0,04491542 0,0983125 GO:0001953|negative regulation of cell-matrix adhesion, ! multicellular organismal water homeostasis GO:0050891 7 7 0,000 0,04491542 0,09819588 ! regulation of ATPase activity GO:0043462 7 7 0,000 0,04491542 0,09807953 ! cell-cell recognition GO:0009988 8 7 0,000 0,04491542 0,09796346 ! hormone catabolic process GO:0042447 7 7 0,000 0,04491542 0,09784767 ! dopamine metabolic process GO:0042417 7 7 0,000 0,04491542 0,09773214 ! cAMP biosynthetic process GO:0006171 7 7 0,000 0,04491542 0,09761689 ! oxygen transport GO:0015671 7 7 0,000 0,04491542 0,09750192 ! pyridine nucleotide biosynthetic process GO:0019363 7 7 0,000 0,04491542 0,09738721 ! biogenic amine catabolic process GO:0042402 7 7 0,000 0,04491542 0,09727277 ! regulation of axon extension GO:0030516 7 7 0,000 0,04491542 0,0971586 ! cell killing GO:0001906 7 7 0,000 0,04491542 0,0970447 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 7 7 0,000 0,04491542 0,09693106 ! adult feeding behavior GO:0008343 7 7 0,000 0,04491542 0,09681769 ! pyrimidine nucleotide catabolic process GO:0006244 7 7 0,000 0,04491542 0,09670459 ! positive regulation of protein polymerization GO:0032273 7 7 0,000 0,04491542 0,09659175 ! T cell receptor signaling pathway GO:0050852 7 7 0,000 0,04491542 0,09647917 ! response to cold GO:0009409 7 7 0,000 0,04491542 0,09636685 ! cell fate commitment GO:0045165 52 52 1,000 0,04511784 0,09668858 ! regulation of body fluid levels GO:0050878 55 52 1,000 0,04511784 0,09657628 ! response to hypoxia GO:0001666 53 53 1,000 0,04669596 0,09983834 ! regulation of T cell activation GO:0050863 53 53 1,000 0,04669596 0,09972266 ! response to oxygen levels GO:0070482 55 54 1,000 0,0482943 0,10301665 ! sulfur metabolic process GO:0006790 55 54 1,000 0,0482943 0,10289756 ! negative regulation of multicellular organismal process GO:0051241 55 54 1,000 0,0482943 0,10277874 ! in utero embryonic development GO:0001701 55 55 1,000 0,04991253 0,10610011 ! protein modification by small protein conjugation or removal GO:0070647 56 55 1,000 0,04991253 0,10597787 ! regulation of skeletal muscle tissue development GO:0048641 8 8 0,000 0,05116871 0,10852005 ! negative regulation of muscle development GO:0048635 8 8 0,000 0,05116871 0,10839532 ! very-long-chain fatty acid metabolic process GO:0000038 8 8 0,000 0,05116871 0,10827087 ! positive regulation of translation GO:0045727 8 8 0,000 0,05116871 0,1081467 ! positive regulation of cell killing GO:0031343 8 8 0,000 0,05116871 0,10802282 ! superoxide anion generation GO:0042554 8 8 0,000 0,05116871 0,10789923 ! sulfur amino acid biosynthetic process GO:0000097 8 8 0,000 0,05116871 0,10777591 ! cGMP metabolic process GO:0046068 8 8 0,000 0,05116871 0,10765288 GO:0006182|cGMP biosynthetic process, ! thyroid gland development GO:0030878 8 8 0,000 0,05116871 0,10753013 ! 'de novo' protein folding GO:0006458 8 8 0,000 0,05116871 0,10740766 ! dicarboxylic acid transport GO:0006835 8 8 0,000 0,05116871 0,10728547 ! phosphoinositide phosphorylation GO:0046854 8 8 0,000 0,05116871 0,10716355 ! embryonic hindlimb morphogenesis GO:0035116 8 8 0,000 0,05116871 0,10704191 ! zinc ion transport GO:0006829 8 8 0,000 0,05116871 0,10692055 ! embryonic forelimb morphogenesis GO:0035115 8 8 0,000 0,05116871 0,10679946 ! folic acid and derivative biosynthetic process GO:0009396 8 8 0,000 0,05116871 0,10667865 ! regulation of neuronal synaptic plasticity GO:0048168 8 8 0,000 0,05116871 0,10655811 ! cardiac muscle contraction GO:0060048 8 8 0,000 0,05116871 0,10643784 ! lipid localization GO:0010876 8 8 0,000 0,05116871 0,10631784 GO:0019915|lipid storage, ! response to pain GO:0048265 8 8 0,000 0,05116871 0,10619811 ! response to cAMP GO:0051591 8 8 0,000 0,05116871 0,10607866 ! COPI coating of Golgi vesicle GO:0048205 8 8 0,000 0,05116871 0,10595947 GO:0048200|Golgi transport vesicle coating, ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 8 0,000 0,05116871 0,10584054 ! negative regulation of ion transport GO:0043271 8 8 0,000 0,05116871 0,10572189 ! regulation of response to extracellular stimulus GO:0032104 8 8 0,000 0,05116871 0,1056035 GO:0032107|regulation of response to nutrient levels, ! adult walking behavior GO:0007628 8 8 0,000 0,05116871 0,10548537 ! sensory perception of taste GO:0050909 8 8 0,000 0,05116871 0,10536751 ! organelle fusion GO:0048284 8 8 0,000 0,05116871 0,10524992 ! pancreas development GO:0031016 8 8 0,000 0,05116871 0,10513258 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 8 8 0,000 0,05116871 0,10501551 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! T cell selection GO:0045058 8 8 0,000 0,05116871 0,10489869 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 8 8 0,000 0,05116871 0,10478214 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 8 8 0,000 0,05116871 0,10466584 ! sperm motility GO:0030317 8 8 0,000 0,05116871 0,10454981 ! regulation of striated muscle contraction GO:0006942 8 8 0,000 0,05116871 0,10443402 ! DNA duplex unwinding GO:0032508 8 8 0,000 0,05116871 0,1043185 GO:0032392|DNA geometric change, ! glycine metabolic process GO:0006544 8 8 0,000 0,05116871 0,10420323 ! ribonucleotide catabolic process GO:0009261 8 8 0,000 0,05116871 0,10408822 ! negative regulation of microtubule depolymerization GO:0007026 8 8 0,000 0,05116871 0,10397346 GO:0031114|regulation of microtubule depolymerization, ! polyamine metabolic process GO:0006595 8 8 0,000 0,05116871 0,10385895 ! Golgi organization GO:0007030 8 8 0,000 0,05116871 0,10374469 ! regulation of stress fiber formation GO:0051492 9 8 0,000 0,05116871 0,10363069 ! fructose metabolic process GO:0006000 8 8 0,000 0,05116871 0,10351693 ! mannose metabolic process GO:0006013 9 8 0,000 0,05116871 0,10340343 ! NAD metabolic process GO:0019674 8 8 0,000 0,05116871 0,10329017 ! sex determination GO:0007530 8 8 0,000 0,05116871 0,10317716 ! negative regulation of mitotic cell cycle GO:0045930 9 8 0,000 0,05116871 0,1030644 ! plasma membrane fusion GO:0045026 8 8 0,000 0,05116871 0,10295188 ! response to fungus GO:0009620 8 8 0,000 0,05116871 0,10283961 ! stem cell differentiation GO:0048863 8 8 0,000 0,05116871 0,10272759 ! alpha-beta T cell activation GO:0046631 8 8 0,000 0,05116871 0,1026158 ! embryonic digit morphogenesis GO:0042733 8 8 0,000 0,05116871 0,10250427 ! regulation of cytokine production during immune response GO:0002718 8 8 0,000 0,05116871 0,10239297 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 0,05116871 0,10228191 ! regulation of vasodilation GO:0042312 8 8 0,000 0,05116871 0,1021711 ! vasoconstriction GO:0042310 8 8 0,000 0,05116871 0,10206052 ! regulation of T cell mediated immunity GO:0002709 8 8 0,000 0,05116871 0,10195019 ! muscle cell development GO:0055001 8 8 0,000 0,05116871 0,10184009 ! nucleoside triphosphate catabolic process GO:0009143 8 8 0,000 0,05116871 0,10173023 ! regulation of fatty acid metabolic process GO:0019217 8 8 0,000 0,05116871 0,10162061 ! sensory perception of pain GO:0019233 8 8 0,000 0,05116871 0,10151122 ! gastrulation with mouth forming second GO:0001702 8 8 0,000 0,05116871 0,10140207 ! immunoglobulin production during immune response GO:0002381 8 8 0,000 0,05116871 0,10129315 GO:0002208|somatic diversification of immunoglobulins during immune response, GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! mRNA cleavage GO:0006379 8 8 0,000 0,05116871 0,10118447 ! chromatin silencing GO:0006342 8 8 0,000 0,05116871 0,10107602 ! tissue regeneration GO:0042246 8 8 0,000 0,05116871 0,1009678 ! salivary gland development GO:0007431 8 8 0,000 0,05116871 0,10085981 ! negative regulation of blood coagulation GO:0030195 9 8 0,000 0,05116871 0,10075206 ! T cell homeostasis GO:0043029 8 8 0,000 0,05116871 0,10064453 ! peptide biosynthetic process GO:0043043 9 8 0,000 0,05116871 0,10053723 ! peptidyl-serine modification GO:0018209 8 8 0,000 0,05116871 0,10043016 ! water homeostasis GO:0030104 8 8 0,000 0,05116871 0,10032332 ! cofactor transport GO:0051181 8 8 0,000 0,05116871 0,10021671 ! regulation of acute inflammatory response GO:0002673 8 8 0,000 0,05116871 0,10011032 ! acid secretion GO:0046717 8 8 0,000 0,05116871 0,10000416 ! C21-steroid hormone biosynthetic process GO:0006700 8 8 0,000 0,05116871 0,09989822 ! protein-chromophore linkage GO:0018298 9 8 0,000 0,05116871 0,09979251 ! regulation of immunoglobulin production GO:0002637 8 8 0,000 0,05116871 0,09968702 ! catecholamine biosynthetic process GO:0042423 8 8 0,000 0,05116871 0,09958176 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 8 8 0,000 0,05116871 0,09947671 ! regulation of generation of precursor metabolites and energy GO:0043467 8 8 0,000 0,05116871 0,09937189 ! aromatic compound biosynthetic process GO:0019438 8 8 0,000 0,05116871 0,09926729 ! regulation of organic acid transport GO:0032890 8 8 0,000 0,05116871 0,09916291 ! positive regulation of calcium ion transport GO:0051928 8 8 0,000 0,05116871 0,09905874 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 8 8 0,000 0,05116871 0,0989548 ! regulation of multi-organism process GO:0043900 8 8 0,000 0,05116871 0,09885107 ! positive regulation of amine transport GO:0051954 8 8 0,000 0,05116871 0,09874756 ! developmental induction GO:0031128 8 8 0,000 0,05116871 0,09864427 GO:0045168|cell-cell signaling involved in cell fate specification, ! peptide hormone secretion GO:0030072 8 8 0,000 0,05116871 0,0985412 ! positive regulation of calcium-mediated signaling GO:0050850 8 8 0,000 0,05116871 0,09843833 ! actin filament polymerization GO:0030041 9 8 0,000 0,05116871 0,09833569 ! peptide hormone processing GO:0016486 8 8 0,000 0,05116871 0,09823325 ! positive regulation of synaptic transmission GO:0050806 8 8 0,000 0,05116871 0,09813103 ! regulation of steroid biosynthetic process GO:0050810 8 8 0,000 0,05116871 0,09802903 ! extracellular structure organization GO:0043062 56 56 1,000 0,05155035 0,09865762 ! peptidyl-amino acid modification GO:0018193 61 59 1,000 0,05657819 0,10816763 ! cellular aromatic compound metabolic process GO:0006725 60 59 1,000 0,05657819 0,10805554 ! protein localization in organelle GO:0033365 59 59 1,000 0,05657819 0,10794368 ! lactation GO:0007595 10 9 0,000 0,05738195 0,10936394 ! embryonic pattern specification GO:0009880 10 9 0,000 0,05738195 0,10925096 ! positive regulation of cell size GO:0045793 9 9 0,000 0,05738195 0,10913822 ! positive regulation of protein complex assembly GO:0031334 9 9 0,000 0,05738195 0,1090257 ! cortical actin cytoskeleton organization GO:0030866 10 9 0,000 0,05738195 0,10891342 ! negative regulation of cell cycle process GO:0010948 9 9 0,000 0,05738195 0,10880137 ! viral genome replication GO:0019079 9 9 0,000 0,05738195 0,10868955 ! phospholipid catabolic process GO:0009395 9 9 0,000 0,05738195 0,10857796 ! copper ion transport GO:0006825 9 9 0,000 0,05738195 0,1084666 ! lipid phosphorylation GO:0046834 9 9 0,000 0,05738195 0,10835546 ! aminoglycan catabolic process GO:0006026 9 9 0,000 0,05738195 0,10824456 ! Golgi vesicle budding GO:0048194 9 9 0,000 0,05738195 0,10813388 ! regulation of cell-cell adhesion GO:0022407 9 9 0,000 0,05738195 0,10802342 ! RNA polyadenylation GO:0043631 9 9 0,000 0,05738195 0,1079132 GO:0006378|mRNA polyadenylation, ! gamma-aminobutyric acid signaling pathway GO:0007214 9 9 0,000 0,05738195 0,10780319 ! regulation of postsynaptic membrane potential GO:0060078 9 9 0,000 0,05738195 0,10769341 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 9 9 0,000 0,05738195 0,10758386 ! negative regulation of cytokine biosynthetic process GO:0042036 9 9 0,000 0,05738195 0,10747452 ! phospholipid efflux GO:0033700 9 9 0,000 0,05738195 0,10736541 ! response to alkaloid GO:0043279 10 9 0,000 0,05738195 0,10725652 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 9 9 0,000 0,05738195 0,10714785 ! cytokine biosynthetic process GO:0042089 9 9 0,000 0,05738195 0,1070394 GO:0042107|cytokine metabolic process, ! negative regulation of gene expression, epigenetic GO:0045814 9 9 0,000 0,05738195 0,10693117 ! regulation of interleukin-2 biosynthetic process GO:0045076 9 9 0,000 0,05738195 0,10682316 ! response to ethanol GO:0045471 9 9 0,000 0,05738195 0,10671537 ! pyrimidine ribonucleotide metabolic process GO:0009218 9 9 0,000 0,05738195 0,10660779 ! activation of pro-apoptotic gene products GO:0008633 9 9 0,000 0,05738195 0,10650043 ! methionine metabolic process GO:0006555 9 9 0,000 0,05738195 0,10639329 ! cerebral cortex development GO:0021987 9 9 0,000 0,05738195 0,10628636 ! response to osmotic stress GO:0006970 9 9 0,000 0,05738195 0,10617965 ! pigmentation during development GO:0048066 9 9 0,000 0,05738195 0,10607315 ! reverse cholesterol transport GO:0043691 9 9 0,000 0,05738195 0,10596687 ! central nervous system neuron development GO:0021954 10 9 0,000 0,05738195 0,10586079 ! pyrimidine ribonucleoside metabolic process GO:0046131 9 9 0,000 0,05738195 0,10575493 ! substrate-bound cell migration GO:0006929 9 9 0,000 0,05738195 0,10564928 ! neurotransmitter metabolic process GO:0042133 11 9 0,000 0,05738195 0,10554384 ! negative regulation of caspase activity GO:0043154 9 9 0,000 0,05738195 0,10543862 ! branching involved in ureteric bud morphogenesis GO:0001658 9 9 0,000 0,05738195 0,1053336 GO:0060675|ureteric bud morphogenesis, ! L-glutamate transport GO:0015813 9 9 0,000 0,05738195 0,10522879 GO:0015800|acidic amino acid transport, ! peptide secretion GO:0002790 9 9 0,000 0,05738195 0,10512419 ! regulation of dephosphorylation GO:0035303 9 9 0,000 0,05738195 0,10501979 ! cotranslational protein targeting to membrane GO:0006613 10 9 0,000 0,05738195 0,10491561 ! positive regulation of alpha-beta T cell differentiation GO:0046638 9 9 0,000 0,05738195 0,10481163 ! ventricular cardiac muscle morphogenesis GO:0055010 9 9 0,000 0,05738195 0,10470785 ! behavioral interaction between organisms GO:0051705 9 9 0,000 0,05738195 0,10460428 ! DNA replication initiation GO:0006270 9 9 0,000 0,05738195 0,10450092 ! prostaglandin metabolic process GO:0006693 9 9 0,000 0,05738195 0,10439776 GO:0006692|prostanoid metabolic process, ! T cell differentiation in the thymus GO:0033077 9 9 0,000 0,05738195 0,1042948 ! histone acetylation GO:0016573 9 9 0,000 0,05738195 0,10419205 ! DNA fragmentation involved in apoptosis GO:0006309 9 9 0,000 0,05738195 0,1040895 ! regulation of immunoglobulin mediated immune response GO:0002889 9 9 0,000 0,05738195 0,10398715 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 10 9 0,000 0,05738195 0,103885 ! positive regulation of oxidoreductase activity GO:0051353 9 9 0,000 0,05738195 0,10378305 ! positive regulation of cytokine secretion GO:0050715 9 9 0,000 0,05738195 0,10368131 ! negative regulation of inflammatory response GO:0050728 9 9 0,000 0,05738195 0,10357976 ! negative regulation of protein secretion GO:0050709 9 9 0,000 0,05738195 0,10347841 ! positive regulation of transmission of nerve impulse GO:0051971 9 9 0,000 0,05738195 0,10337725 ! collagen catabolic process GO:0030574 9 9 0,000 0,05738195 0,1032763 ! aromatic amino acid family catabolic process GO:0009074 9 9 0,000 0,05738195 0,10317554 ! purine base metabolic process GO:0006144 9 9 0,000 0,05738195 0,10307498 ! gas transport GO:0015669 9 9 0,000 0,05738195 0,10297462 ! cholesterol efflux GO:0033344 9 9 0,000 0,05738195 0,10287445 ! regulation of leukocyte mediated cytotoxicity GO:0001910 9 9 0,000 0,05738195 0,10277447 ! estrogen receptor signaling pathway GO:0030520 9 9 0,000 0,05738195 0,10267469 ! somatic recombination of immunoglobulin gene segments GO:0016447 9 9 0,000 0,05738195 0,1025751 ! regulation of actin filament bundle formation GO:0032231 10 9 0,000 0,05738195 0,10247571 ! defense response to virus GO:0051607 9 9 0,000 0,05738195 0,10237651 ! regulation of calcium-mediated signaling GO:0050848 9 9 0,000 0,05738195 0,1022775 ! actin filament-based movement GO:0030048 9 9 0,000 0,05738195 0,10217868 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 9 9 0,000 0,05738195 0,10208005 ! negative regulation of cellular protein metabolic process GO:0032269 60 60 1,000 0,05829124 0,10359765 ! positive regulation of cellular protein metabolic process GO:0032270 61 61 1,000 0,06002235 0,10657147 ! axonogenesis GO:0007409 66 62 1,000 0,06177121 0,10957106 ! regulation of cellular component biogenesis GO:0044087 63 62 1,000 0,06177121 0,10946571 ! protein import GO:0017038 62 62 1,000 0,06177121 0,10936055 ! regulation of lymphocyte activation GO:0051249 62 62 1,000 0,06177121 0,1092556 ! protein import into nucleus, docking GO:0000059 10 10 0,000 0,0635554 0,11230356 ! regulation of protein ubiquitination GO:0031396 10 10 0,000 0,0635554 0,11219599 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 10 10 0,000 0,0635554 0,11208862 ! regulation of glucose metabolic process GO:0010906 10 10 0,000 0,0635554 0,11198146 ! ER-associated protein catabolic process GO:0030433 10 10 0,000 0,0635554 0,11187451 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of cell killing GO:0031341 10 10 0,000 0,0635554 0,11176776 ! pteridine and derivative metabolic process GO:0042558 10 10 0,000 0,0635554 0,11166121 ! positive regulation of anti-apoptosis GO:0045768 10 10 0,000 0,0635554 0,11155487 GO:0045767|regulation of anti-apoptosis, ! cortical cytoskeleton organization GO:0030865 11 10 0,000 0,0635554 0,11144873 ! regulation of lipid biosynthetic process GO:0046890 10 10 0,000 0,0635554 0,11134279 ! reciprocal meiotic recombination GO:0007131 10 10 0,000 0,0635554 0,11123705 ! hormone secretion GO:0046879 10 10 0,000 0,0635554 0,11113151 ! glucosamine metabolic process GO:0006041 10 10 0,000 0,0635554 0,11102617 GO:0006044|N-acetylglucosamine metabolic process, ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 10 10 0,000 0,0635554 0,11092103 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! inositol metabolic process GO:0006020 10 10 0,000 0,0635554 0,11081609 ! cAMP metabolic process GO:0046058 10 10 0,000 0,0635554 0,11071135 ! vesicle targeting, to, from or within Golgi GO:0048199 10 10 0,000 0,0635554 0,11060681 ! transcription from RNA polymerase III promoter GO:0006383 10 10 0,000 0,0635554 0,11050246 ! forelimb morphogenesis GO:0035136 10 10 0,000 0,0635554 0,11039831 ! glial cell development GO:0021782 10 10 0,000 0,0635554 0,11029436 ! phototransduction GO:0007602 11 10 0,000 0,0635554 0,1101906 ! calcium-independent cell-cell adhesion GO:0016338 10 10 0,000 0,0635554 0,11008704 ! auditory receptor cell differentiation GO:0042491 10 10 0,000 0,0635554 0,10998367 ! fat cell differentiation GO:0045444 10 10 0,000 0,0635554 0,1098805 ! myoblast differentiation GO:0045445 10 10 0,000 0,0635554 0,10977752 ! centrosome cycle GO:0007098 10 10 0,000 0,0635554 0,10967473 ! inactivation of MAPK activity GO:0000188 10 10 0,000 0,0635554 0,10957213 ! positive regulation of proteolysis GO:0045862 10 10 0,000 0,0635554 0,10946973 ! response to carbohydrate stimulus GO:0009743 10 10 0,000 0,0635554 0,10936752 ! regulation of survival gene product expression GO:0045884 10 10 0,000 0,0635554 0,10926549 ! epidermis morphogenesis GO:0048730 10 10 0,000 0,0635554 0,10916366 ! protein polyubiquitination GO:0000209 10 10 0,000 0,0635554 0,10906202 ! glutamate metabolic process GO:0006536 11 10 0,000 0,0635554 0,10896057 ! plasma membrane organization GO:0007009 10 10 0,000 0,0635554 0,1088593 ! cell-substrate junction assembly GO:0007044 11 10 0,000 0,0635554 0,10875823 ! lysosomal transport GO:0007041 10 10 0,000 0,0635554 0,10865734 ! cellular response to unfolded protein GO:0034620 10 10 0,000 0,0635554 0,10855664 GO:0030968|endoplasmic reticulum unfolded protein response, ! central nervous system neuron differentiation GO:0021953 11 10 0,000 0,0635554 0,10845612 ! purine ribonucleoside metabolic process GO:0046128 10 10 0,000 0,0635554 0,10835579 GO:0042278|purine nucleoside metabolic process, ! vesicle coating GO:0006901 10 10 0,000 0,0635554 0,10825565 ! exocrine system development GO:0035272 10 10 0,000 0,0635554 0,10815569 ! cell structure disassembly during apoptosis GO:0006921 10 10 0,000 0,0635554 0,10805591 ! embryo implantation GO:0007566 11 10 0,000 0,0635554 0,10795632 ! regulation of protein binding GO:0043393 11 10 0,000 0,0635554 0,10785692 ! protein targeting to peroxisome GO:0006625 10 10 0,000 0,0635554 0,10775769 ! protein targeting to mitochondrion GO:0006626 10 10 0,000 0,0635554 0,10765865 GO:0070585|protein localization in mitochondrion, ! regulation of alpha-beta T cell differentiation GO:0046637 10 10 0,000 0,0635554 0,10755979 ! intermediate filament cytoskeleton organization GO:0045104 10 10 0,000 0,0635554 0,10746111 ! protein export from nucleus GO:0006611 10 10 0,000 0,0635554 0,10736261 ! negative regulation of immune response GO:0050777 10 10 0,000 0,0635554 0,1072643 ! cytolysis GO:0019835 10 10 0,000 0,0635554 0,10716616 ! positive regulation of biomineral formation GO:0070169 10 10 0,000 0,0635554 0,1070682 GO:0030501|positive regulation of bone mineralization, ! mismatch repair GO:0006298 10 10 0,000 0,0635554 0,10697042 ! regulation of B cell differentiation GO:0045577 10 10 0,000 0,0635554 0,10687282 ! histone deacetylation GO:0016575 10 10 0,000 0,0635554 0,1067754 ! mRNA splice site selection GO:0006376 11 10 0,000 0,0635554 0,10667815 ! synaptic vesicle transport GO:0048489 11 10 0,000 0,0635554 0,10658108 ! gland morphogenesis GO:0022612 10 10 0,000 0,0635554 0,10648419 ! positive regulation of neurological system process GO:0031646 10 10 0,000 0,0635554 0,10638748 ! sphingolipid biosynthetic process GO:0030148 10 10 0,000 0,0635554 0,10629093 GO:0046467|membrane lipid biosynthetic process, ! sphingolipid catabolic process GO:0030149 10 10 0,000 0,0635554 0,10619457 GO:0046466|membrane lipid catabolic process, ! nerve-nerve synaptic transmission GO:0007270 10 10 0,000 0,0635554 0,10609838 ! regulation of erythrocyte differentiation GO:0045646 10 10 0,000 0,0635554 0,10600236 ! regulation of epidermis development GO:0045682 10 10 0,000 0,0635554 0,10590652 ! folic acid and derivative metabolic process GO:0006760 10 10 0,000 0,0635554 0,10581085 ! negative regulation of neuron differentiation GO:0045665 10 10 0,000 0,0635554 0,10571535 ! aspartate family amino acid biosynthetic process GO:0009067 10 10 0,000 0,0635554 0,10562003 ! regulation of BMP signaling pathway GO:0030510 10 10 0,000 0,0635554 0,10552487 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 10 10 0,000 0,0635554 0,10542989 ! lymphocyte homeostasis GO:0002260 10 10 0,000 0,0635554 0,10533508 ! nerve development GO:0021675 10 10 0,000 0,0635554 0,10524044 ! gut development GO:0048565 10 10 0,000 0,0635554 0,10514597 ! embryonic organ morphogenesis GO:0048562 10 10 0,000 0,0635554 0,10505167 ! mRNA 3'-end processing GO:0031124 10 10 0,000 0,0635554 0,10495754 ! antigen receptor-mediated signaling pathway GO:0050851 10 10 0,000 0,0635554 0,10486357 ! negative regulation of coagulation GO:0050819 11 10 0,000 0,0635554 0,10476978 ! regulation of response to external stimulus GO:0032101 65 64 1,000 0,06532101 0,10758412 ! positive regulation of cellular component organization GO:0051130 65 65 1,000 0,06712138 0,11045063 ! DNA packaging GO:0006323 66 66 1,000 0,06893834 0,1133393 ! protein secretion GO:0009306 11 11 0,000 0,06968932 0,11447185 ! oligosaccharide metabolic process GO:0009311 11 11 0,000 0,06968932 0,11436992 ! myeloid leukocyte differentiation GO:0002573 12 11 0,000 0,06968932 0,11426817 ! negative regulation of defense response GO:0031348 11 11 0,000 0,06968932 0,11416659 ! determination of bilateral symmetry GO:0009855 11 11 0,000 0,06968932 0,1140652 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! positive regulation of hormone secretion GO:0046887 11 11 0,000 0,06968932 0,11396399 ! phosphatidylinositol metabolic process GO:0046488 11 11 0,000 0,06968932 0,11386296 ! skin development GO:0043588 11 11 0,000 0,06968932 0,11376211 ! cellular component assembly involved in morphogenesis GO:0010927 11 11 0,000 0,06968932 0,11366143 ! microtubule-based transport GO:0010970 11 11 0,000 0,06968932 0,11356094 ! endothelial cell migration GO:0043542 11 11 0,000 0,06968932 0,11346062 ! peroxisomal transport GO:0043574 11 11 0,000 0,06968932 0,11336048 ! protein amino acid methylation GO:0006479 11 11 0,000 0,06968932 0,11326051 GO:0008213|protein amino acid alkylation, ! protein amino acid acetylation GO:0006473 11 11 0,000 0,06968932 0,11316072 ! heart contraction GO:0060047 11 11 0,000 0,06968932 0,11306111 GO:0003015|heart process, ! detection of light stimulus involved in sensory perception GO:0050962 12 11 0,000 0,06968932 0,11296167 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 11 11 0,000 0,06968932 0,11286241 ! T cell proliferation GO:0042098 11 11 0,000 0,06968932 0,11276332 ! regulation of transmembrane transporter activity GO:0022898 11 11 0,000 0,06968932 0,1126644 GO:0032412|regulation of ion transmembrane transporter activity, GO:0032409|regulation of transporter activity, ! negative regulation of endothelial cell proliferation GO:0001937 11 11 0,000 0,06968932 0,11256566 ! spinal cord development GO:0021510 11 11 0,000 0,06968932 0,11246709 ! smooth muscle contraction GO:0006939 11 11 0,000 0,06968932 0,11236869 ! cellular macromolecular complex disassembly GO:0034623 12 11 0,000 0,06968932 0,11227047 ! digestive system process GO:0022600 11 11 0,000 0,06968932 0,11217242 ! mitotic spindle organization GO:0007052 11 11 0,000 0,06968932 0,11207454 ! fucose metabolic process GO:0006004 11 11 0,000 0,06968932 0,11197683 ! membrane budding GO:0006900 11 11 0,000 0,06968932 0,11187928 ! monoamine transport GO:0015844 11 11 0,000 0,06968932 0,11178191 ! regulation of cellular ketone metabolic process GO:0010565 11 11 0,000 0,06968932 0,11168471 ! response to lipopolysaccharide GO:0032496 11 11 0,000 0,06968932 0,11158768 ! body fluid secretion GO:0007589 11 11 0,000 0,06968932 0,11149081 ! positive regulation of alpha-beta T cell activation GO:0046635 11 11 0,000 0,06968932 0,11139412 ! intermediate filament-based process GO:0045103 11 11 0,000 0,06968932 0,11129759 ! cardiac muscle tissue morphogenesis GO:0055008 11 11 0,000 0,06968932 0,11120123 GO:0060415|muscle tissue morphogenesis, ! interaction with host GO:0051701 11 11 0,000 0,06968932 0,11110503 ! membrane depolarization GO:0051899 11 11 0,000 0,06968932 0,111009 ! regulation of interleukin-2 production GO:0032663 11 11 0,000 0,06968932 0,11091314 ! regulation of ARF GTPase activity GO:0032312 11 11 0,000 0,06968932 0,11081744 ! oogenesis GO:0048477 11 11 0,000 0,06968932 0,11072191 ! negative regulation of angiogenesis GO:0016525 11 11 0,000 0,06968932 0,11062654 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 11 11 0,000 0,06968932 0,11053134 ! regulation of cellular carbohydrate metabolic process GO:0010675 11 11 0,000 0,06968932 0,1104363 GO:0006109|regulation of carbohydrate metabolic process, ! vitamin transport GO:0051180 11 11 0,000 0,06968932 0,11034142 ! muscle maintenance GO:0046716 12 11 0,000 0,06968932 0,11024671 ! vitamin A metabolic process GO:0006776 11 11 0,000 0,06968932 0,11015216 ! hindbrain development GO:0030902 11 11 0,000 0,06968932 0,11005777 ! steroid catabolic process GO:0006706 11 11 0,000 0,06968932 0,10996354 ! endocrine process GO:0050886 11 11 0,000 0,06968932 0,10986948 GO:0001990|regulation of systemic arterial blood pressure by hormone, ! aromatic amino acid family metabolic process GO:0009072 11 11 0,000 0,06968932 0,10977557 ! proximal/distal pattern formation GO:0009954 11 11 0,000 0,06968932 0,10968183 ! somatic diversification of immunoglobulins GO:0016445 11 11 0,000 0,06968932 0,10958824 ! RNA 3'-end processing GO:0031123 11 11 0,000 0,06968932 0,10949482 ! cell morphogenesis involved in neuron differentiation GO:0048667 72 67 1,000 0,07077161 0,11110057 GO:0048812|neuron projection morphogenesis, GO:0048858|cell projection morphogenesis, ! negative regulation of cell differentiation GO:0045596 68 67 1,000 0,07077161 0,11100602 ! Ras protein signal transduction GO:0007265 69 67 1,000 0,07077161 0,11091163 ! regionalization GO:0003002 70 69 1,000 0,07448596 0,1166335 ! response to nutrient levels GO:0031667 69 69 1,000 0,07448596 0,11653449 ! regulation of leukocyte activation GO:0002694 69 69 1,000 0,07448596 0,11643565 ! translational initiation GO:0006413 12 12 0,000 0,07578395 0,11836425 ! positive regulation of angiogenesis GO:0045766 12 12 0,000 0,07578395 0,11826402 ! DNA catabolic process, endonucleolytic GO:0000737 12 12 0,000 0,07578395 0,11816397 ! iron ion transport GO:0006826 13 12 0,000 0,07578395 0,11806409 ! phosphatidylcholine metabolic process GO:0046470 12 12 0,000 0,07578395 0,11796437 ! amino sugar metabolic process GO:0006040 12 12 0,000 0,07578395 0,11786482 ! post-Golgi vesicle-mediated transport GO:0006892 12 12 0,000 0,07578395 0,11776544 ! heterophilic cell adhesion GO:0007157 12 12 0,000 0,07578395 0,11766623 ! collagen metabolic process GO:0032963 12 12 0,000 0,07578395 0,11756718 ! hindlimb morphogenesis GO:0035137 12 12 0,000 0,07578395 0,1174683 ! glutamate signaling pathway GO:0007215 12 12 0,000 0,07578395 0,11736959 ! C21-steroid hormone metabolic process GO:0008207 13 12 0,000 0,07578395 0,11727104 ! regulation of muscle cell differentiation GO:0051147 13 12 0,000 0,07578395 0,11717266 ! cellular response to hydrogen peroxide GO:0070301 12 12 0,000 0,07578395 0,11707444 GO:0042744|hydrogen peroxide catabolic process, ! negative regulation of peptidase activity GO:0010466 12 12 0,000 0,07578395 0,11697639 ! actomyosin structure organization GO:0031032 12 12 0,000 0,07578395 0,1168785 ! microtubule organizing center organization GO:0031023 12 12 0,000 0,07578395 0,11678078 GO:0051297|centrosome organization, ! positive regulation of endocytosis GO:0045807 12 12 0,000 0,07578395 0,11668322 ! retinoid metabolic process GO:0001523 12 12 0,000 0,07578395 0,11658582 GO:0016101|diterpenoid metabolic process, ! mitotic chromosome condensation GO:0007076 12 12 0,000 0,07578395 0,11648858 ! positive regulation of innate immune response GO:0045089 12 12 0,000 0,07578395 0,11639151 ! GPI anchor biosynthetic process GO:0006506 12 12 0,000 0,07578395 0,1162946 GO:0006505|GPI anchor metabolic process, ! glycoprotein catabolic process GO:0006516 13 12 0,000 0,07578395 0,11619785 ! acute-phase response GO:0006953 12 12 0,000 0,07578395 0,11610126 ! deoxyribonucleotide catabolic process GO:0009264 12 12 0,000 0,07578395 0,11600483 ! vacuolar transport GO:0007034 12 12 0,000 0,07578395 0,11590856 ! polysaccharide catabolic process GO:0000272 12 12 0,000 0,07578395 0,11581245 ! vesicle docking during exocytosis GO:0006904 12 12 0,000 0,07578395 0,1157165 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 12 12 0,000 0,07578395 0,11562071 ! barbed-end actin filament capping GO:0051016 12 12 0,000 0,07578395 0,11552507 GO:0051693|actin filament capping, ! osteoblast differentiation GO:0001649 12 12 0,000 0,07578395 0,1154296 ! male gonad development GO:0008584 12 12 0,000 0,07578395 0,11533428 ! regulation of insulin secretion GO:0050796 12 12 0,000 0,07578395 0,11523912 ! regulation of alpha-beta T cell activation GO:0046634 12 12 0,000 0,07578395 0,11514412 ! renal system process GO:0003014 12 12 0,000 0,07578395 0,11504927 ! regulation of tumor necrosis factor production GO:0032680 12 12 0,000 0,07578395 0,11495458 ! regulation of steroid metabolic process GO:0019218 12 12 0,000 0,07578395 0,11486004 ! regulation of interleukin-6 production GO:0032675 12 12 0,000 0,07578395 0,11476566 ! pallium development GO:0021543 13 12 0,000 0,07578395 0,11467144 ! cell fate determination GO:0001709 12 12 0,000 0,07578395 0,11457737 ! regulation of chromosome organization GO:0033044 12 12 0,000 0,07578395 0,11448345 ! somitogenesis GO:0001756 13 12 0,000 0,07578395 0,11438969 ! regulation of response to biotic stimulus GO:0002831 12 12 0,000 0,07578395 0,11429608 ! positive regulation of adaptive immune response GO:0002821 12 12 0,000 0,07578395 0,11420263 ! detection of light stimulus GO:0009583 13 12 0,000 0,07578395 0,11410932 ! synaptogenesis GO:0007416 12 12 0,000 0,07578395 0,11401617 ! fat-soluble vitamin metabolic process GO:0006775 12 12 0,000 0,07578395 0,11392318 ! hormone transport GO:0009914 12 12 0,000 0,07578395 0,11383033 ! neurotransmitter secretion GO:0007269 14 12 0,000 0,07578395 0,11373763 ! heme biosynthetic process GO:0006783 12 12 0,000 0,07578395 0,11364509 ! spermatid differentiation GO:0048515 13 12 0,000 0,07578395 0,11355269 GO:0007286|spermatid development, ! aromatic compound catabolic process GO:0019439 13 12 0,000 0,07578395 0,11346045 ! neural tube closure GO:0001843 13 12 0,000 0,07578395 0,11336835 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! regulation of mitotic metaphase/anaphase transition GO:0030071 13 12 0,000 0,07578395 0,11327641 ! negative regulation of translation GO:0017148 12 12 0,000 0,07578395 0,11318461 ! regulation of microtubule polymerization or depolymerization GO:0031110 12 12 0,000 0,07578395 0,11309297 ! positive regulation of transport GO:0051050 71 70 1,000 0,0763665 0,11387011 ! cell part morphogenesis GO:0032990 75 70 1,000 0,0763665 0,11377806 ! negative regulation of signal transduction GO:0009968 71 71 1,000 0,07826224 0,11650833 ! regulation of cell activation GO:0050865 71 71 1,000 0,07826224 0,11641429 ! response to extracellular stimulus GO:0009991 72 72 1,000 0,08017292 0,11916024 ! positive regulation of DNA replication GO:0045740 14 13 0,000 0,08183953 0,12153928 ! negative regulation of actin filament polymerization GO:0030837 13 13 0,000 0,08183953 0,12144142 ! phenol metabolic process GO:0018958 13 13 0,000 0,08183953 0,12134372 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, GO:0009712|catechol metabolic process, ! gluconeogenesis GO:0006094 13 13 0,000 0,08183953 0,12124618 ! negative regulation of hormone secretion GO:0046888 13 13 0,000 0,08183953 0,12114879 ! 2'-deoxyribonucleotide metabolic process GO:0009394 13 13 0,000 0,08183953 0,12105156 GO:0019692|deoxyribose phosphate metabolic process, ! intra-Golgi vesicle-mediated transport GO:0006891 13 13 0,000 0,08183953 0,12095449 ! glycosaminoglycan biosynthetic process GO:0006024 13 13 0,000 0,08183953 0,12085757 ! regeneration GO:0031099 13 13 0,000 0,08183953 0,12076081 ! keratinization GO:0031424 13 13 0,000 0,08183953 0,1206642 ! post-embryonic development GO:0009791 14 13 0,000 0,08183953 0,12056774 ! negative regulation of protein modification process GO:0031400 13 13 0,000 0,08183953 0,12047144 ! patterning of blood vessels GO:0001569 13 13 0,000 0,08183953 0,1203753 ! regulation of DNA recombination GO:0000018 13 13 0,000 0,08183953 0,1202793 ! regulation of innate immune response GO:0045088 13 13 0,000 0,08183953 0,12018346 ! multicellular organismal macromolecule metabolic process GO:0044259 13 13 0,000 0,08183953 0,12008778 ! response to corticosteroid stimulus GO:0031960 13 13 0,000 0,08183953 0,11999224 GO:0051384|response to glucocorticoid stimulus, ! multicellular organismal catabolic process GO:0044243 13 13 0,000 0,08183953 0,11989686 ! autophagy GO:0006914 13 13 0,000 0,08183953 0,11980163 ! actin filament bundle formation GO:0051017 13 13 0,000 0,08183953 0,11970654 ! ureteric bud development GO:0001657 13 13 0,000 0,08183953 0,11961161 ! coenzyme catabolic process GO:0009109 13 13 0,000 0,08183953 0,11951684 GO:0046356|acetyl-CoA catabolic process, GO:0006099|tricarboxylic acid cycle, ! negative regulation of protein kinase cascade GO:0010741 13 13 0,000 0,08183953 0,11942221 ! purine nucleoside monophosphate metabolic process GO:0009126 13 13 0,000 0,08183953 0,11932773 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of peptide secretion GO:0002791 13 13 0,000 0,08183953 0,1192334 ! regulation of axonogenesis GO:0050770 14 13 0,000 0,08183953 0,11913922 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 14 13 0,000 0,08183953 0,11904518 ! nucleotide-excision repair, DNA gap filling GO:0006297 13 13 0,000 0,08183953 0,1189513 ! vasodilation GO:0042311 14 13 0,000 0,08183953 0,11885756 ! positive regulation of leukocyte mediated immunity GO:0002705 13 13 0,000 0,08183953 0,11876397 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 13 13 0,000 0,08183953 0,11867053 ! glycosphingolipid metabolic process GO:0006687 13 13 0,000 0,08183953 0,11857724 GO:0006664|glycolipid metabolic process, ! neural crest cell migration GO:0001755 14 13 0,000 0,08183953 0,11848409 ! neutrophil chemotaxis GO:0030593 14 13 0,000 0,08183953 0,11839109 ! long-chain fatty acid transport GO:0015909 13 13 0,000 0,08183953 0,11829823 ! immunoglobulin production GO:0002377 13 13 0,000 0,08183953 0,11820552 GO:0002440|production of molecular mediator of immune response, ! regulation of cell-substrate adhesion GO:0010810 14 13 0,000 0,08183953 0,11811296 GO:0001952|regulation of cell-matrix adhesion, ! negative regulation of myeloid cell differentiation GO:0045638 13 13 0,000 0,08183953 0,11802054 ! response to cytokine stimulus GO:0034097 13 13 0,000 0,08183953 0,11792826 ! terpenoid metabolic process GO:0006721 13 13 0,000 0,08183953 0,11783613 ! alkene biosynthetic process GO:0043450 13 13 0,000 0,08183953 0,11774414 GO:0019370|leukotriene biosynthetic process, ! purine nucleotide catabolic process GO:0006195 13 13 0,000 0,08183953 0,1176523 ! porphyrin biosynthetic process GO:0006779 13 13 0,000 0,08183953 0,1175606 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of cytokine production GO:0001818 13 13 0,000 0,08183953 0,11746904 ! camera-type eye morphogenesis GO:0048593 13 13 0,000 0,08183953 0,11737762 ! pyrimidine nucleoside metabolic process GO:0006213 13 13 0,000 0,08183953 0,11728635 ! blastocyst development GO:0001824 13 13 0,000 0,08183953 0,11719522 ! water-soluble vitamin biosynthetic process GO:0042364 13 13 0,000 0,08183953 0,11710423 ! regulation of amine transport GO:0051952 13 13 0,000 0,08183953 0,11701338 ! inner ear receptor cell differentiation GO:0060113 13 13 0,000 0,08183953 0,11692267 ! neuron fate commitment GO:0048663 14 14 0,000 0,0878563 0,12542151 ! sulfur amino acid metabolic process GO:0000096 14 14 0,000 0,0878563 0,12532443 ! regulation of interferon-gamma production GO:0032649 14 14 0,000 0,0878563 0,12522751 ! pyruvate metabolic process GO:0006090 14 14 0,000 0,0878563 0,12513073 ! cellular aldehyde metabolic process GO:0006081 14 14 0,000 0,0878563 0,12503411 ! acetyl-CoA metabolic process GO:0006084 14 14 0,000 0,0878563 0,12493763 ! cellular iron ion homeostasis GO:0006879 14 14 0,000 0,0878563 0,1248413 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 14 14 0,000 0,0878563 0,12474512 ! protein amino acid acylation GO:0043543 14 14 0,000 0,0878563 0,12464909 ! regulation of neuron projection development GO:0010975 15 14 0,000 0,0878563 0,12455321 ! protein amino acid deacetylation GO:0006476 14 14 0,000 0,0878563 0,12445747 ! aminoglycan biosynthetic process GO:0006023 14 14 0,000 0,0878563 0,12436188 ! vesicle docking GO:0048278 14 14 0,000 0,0878563 0,12426644 ! superoxide metabolic process GO:0006801 15 14 0,000 0,0878563 0,12417114 ! macromolecular complex disassembly GO:0032984 15 14 0,000 0,0878563 0,12407599 ! mechanoreceptor differentiation GO:0042490 14 14 0,000 0,0878563 0,12398099 ! isoprenoid biosynthetic process GO:0008299 14 14 0,000 0,0878563 0,12388613 ! hair cycle GO:0042633 14 14 0,000 0,0878563 0,12379141 GO:0022404|molting cycle process, GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042303|molting cycle, ! negative regulation of epithelial cell proliferation GO:0050680 14 14 0,000 0,0878563 0,12369684 ! immune response-activating cell surface receptor signaling pathway GO:0002429 14 14 0,000 0,0878563 0,12360242 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! response to retinoic acid GO:0032526 14 14 0,000 0,0878563 0,12350814 GO:0033189|response to vitamin A, ! multicellular organismal response to stress GO:0033555 14 14 0,000 0,0878563 0,123414 ! lysosome organization GO:0007040 14 14 0,000 0,0878563 0,12332001 ! actin polymerization or depolymerization GO:0008154 15 14 0,000 0,0878563 0,12322616 ! D-ribose metabolic process GO:0006014 14 14 0,000 0,0878563 0,12313245 ! negative regulation of phosphorus metabolic process GO:0010563 14 14 0,000 0,0878563 0,12303888 GO:0045936|negative regulation of phosphate metabolic process, ! peptide transport GO:0015833 14 14 0,000 0,0878563 0,12294546 ! primary neural tube formation GO:0014020 15 14 0,000 0,0878563 0,12285218 ! peptide cross-linking GO:0018149 14 14 0,000 0,0878563 0,12275904 ! vitamin biosynthetic process GO:0009110 14 14 0,000 0,0878563 0,12266604 ! response to organic cyclic substance GO:0014070 15 14 0,000 0,0878563 0,12257318 ! leukotriene metabolic process GO:0006691 14 14 0,000 0,0878563 0,12248046 ! regulation of vasoconstriction GO:0019229 14 14 0,000 0,0878563 0,12238788 ! formation of primary germ layer GO:0001704 14 14 0,000 0,0878563 0,12229545 GO:0001707|mesoderm formation, ! collagen fibril organization GO:0030199 14 14 0,000 0,0878563 0,12220315 ! proteoglycan biosynthetic process GO:0030166 14 14 0,000 0,0878563 0,12211099 ! regulation of blood coagulation GO:0030193 15 14 0,000 0,0878563 0,12201897 ! positive regulation of inflammatory response GO:0050729 14 14 0,000 0,0878563 0,12192709 ! group transfer coenzyme metabolic process GO:0006752 14 14 0,000 0,0878563 0,12183534 ! positive regulation of osteoblast differentiation GO:0045669 14 14 0,000 0,0878563 0,12174374 ! neuromuscular process controlling balance GO:0050885 14 14 0,000 0,0878563 0,12165227 ! aspartate family amino acid metabolic process GO:0009066 14 14 0,000 0,0878563 0,12156094 ! response to molecule of bacterial origin GO:0002237 14 14 0,000 0,0878563 0,12146974 ! negative regulation of protein polymerization GO:0032272 14 14 0,000 0,0878563 0,12137869 ! negative regulation of cell communication GO:0010648 76 76 1,000 0,08795976 0,12143058 ! positive regulation of multicellular organismal process GO:0051240 76 76 1,000 0,08795976 0,12133969 ! positive regulation of fibroblast proliferation GO:0048146 15 15 0,000 0,09383453 0,12934707 ! negative regulation of actin filament depolymerization GO:0030835 15 15 0,000 0,09383453 0,1292504 ! positive regulation of ossification GO:0045778 15 15 0,000 0,09383453 0,12915387 GO:0046852|positive regulation of bone remodeling, GO:0034105|positive regulation of tissue remodeling, ! negative regulation of protein complex assembly GO:0031333 15 15 0,000 0,09383453 0,12905749 ! protein amino acid O-linked glycosylation GO:0006493 15 15 0,000 0,09383453 0,12896125 ! cellular polysaccharide biosynthetic process GO:0033692 15 15 0,000 0,09383453 0,12886515 ! proteoglycan metabolic process GO:0006029 15 15 0,000 0,09383453 0,1287692 ! response to vitamin GO:0033273 15 15 0,000 0,09383453 0,12867339 ! odontogenesis of dentine-containing tooth GO:0042475 15 15 0,000 0,09383453 0,12857772 ! detection of stimulus involved in sensory perception GO:0050906 16 15 0,000 0,09383453 0,12848219 ! insulin receptor signaling pathway GO:0008286 17 15 0,000 0,09383453 0,12838681 ! ovarian follicle development GO:0001541 15 15 0,000 0,09383453 0,12829157 ! antigen processing and presentation of peptide antigen GO:0048002 15 15 0,000 0,09383453 0,12819647 ! regulation of smooth muscle contraction GO:0006940 15 15 0,000 0,09383453 0,1281015 ! deoxyribonucleotide metabolic process GO:0009262 15 15 0,000 0,09383453 0,12800669 ! complement activation, classical pathway GO:0006958 15 15 0,000 0,09383453 0,12791201 ! heme metabolic process GO:0042168 15 15 0,000 0,09383453 0,12781747 ! mesoderm morphogenesis GO:0048332 15 15 0,000 0,09383453 0,12772307 ! response to mechanical stimulus GO:0009612 15 15 0,000 0,09383453 0,12762881 ! hydrogen peroxide metabolic process GO:0042743 15 15 0,000 0,09383453 0,12753468 ! regulation of biomineral formation GO:0070167 15 15 0,000 0,09383453 0,1274407 GO:0030500|regulation of bone mineralization, ! regulation of production of molecular mediator of immune response GO:0002700 15 15 0,000 0,09383453 0,12734686 ! cyclic nucleotide biosynthetic process GO:0009190 15 15 0,000 0,09383453 0,12725315 ! cholesterol biosynthetic process GO:0006695 15 15 0,000 0,09383453 0,12715958 ! phospholipid transport GO:0015914 15 15 0,000 0,09383453 0,12706615 ! leukocyte homeostasis GO:0001776 15 15 0,000 0,09383453 0,12697286 ! regulation of cytokine secretion GO:0050707 15 15 0,000 0,09383453 0,1268797 ! glutathione metabolic process GO:0006749 16 15 0,000 0,09383453 0,12678668 ! nicotinamide metabolic process GO:0006769 15 15 0,000 0,09383453 0,1266938 GO:0046496|nicotinamide nucleotide metabolic process, ! positive regulation of B cell activation GO:0050871 15 15 0,000 0,09383453 0,12660105 ! cellular alkene metabolic process GO:0043449 15 15 0,000 0,09383453 0,12650844 ! positive regulation of immune effector process GO:0002699 15 15 0,000 0,09383453 0,12641596 ! nuclear transport GO:0051169 79 79 1,000 0,09394397 0,12647096 GO:0006913|nucleocytoplasmic transport, ! neuron projection development GO:0031175 85 80 1,000 0,09596481 0,12909719 ! tube development GO:0035295 83 81 1,000 0,09799829 0,13173657 ! lymphocyte activation GO:0046649 82 81 1,000 0,09799829 0,13164056 ! alkaloid metabolic process GO:0009820 16 16 0,000 0,09977443 0,13392882 ! spliceosomal snRNP biogenesis GO:0000387 16 16 0,000 0,09977443 0,13383135 ! learning GO:0007612 16 16 0,000 0,09977443 0,13373402 ! circadian rhythm GO:0007623 16 16 0,000 0,09977443 0,13363683 ! inner ear morphogenesis GO:0042472 16 16 0,000 0,09977443 0,13353978 ! positive regulation of mitosis GO:0045840 16 16 0,000 0,09977443 0,13344287 GO:0051785|positive regulation of nuclear division, ! vacuole organization GO:0007033 16 16 0,000 0,09977443 0,1333461 ! positive regulation of cytoskeleton organization GO:0051495 16 16 0,000 0,09977443 0,13324948 ! vesicle targeting GO:0006903 17 16 0,000 0,09977443 0,13315299 ! segmentation GO:0035282 17 16 0,000 0,09977443 0,13305664 ! fatty acid beta-oxidation GO:0006635 16 16 0,000 0,09977443 0,13296043 ! triglyceride metabolic process GO:0006641 16 16 0,000 0,09977443 0,13286436 ! iron ion homeostasis GO:0055072 16 16 0,000 0,09977443 0,13276843 ! lymphocyte proliferation GO:0046651 16 16 0,000 0,09977443 0,13267264 ! regulation of systemic arterial blood pressure GO:0003073 17 16 0,000 0,09977443 0,13257698 ! cell fate specification GO:0001708 16 16 0,000 0,09977443 0,13248147 ! pentose metabolic process GO:0019321 16 16 0,000 0,09977443 0,13238609 ! fatty acid transport GO:0015908 16 16 0,000 0,09977443 0,13229085 ! positive regulation of MAPKKK cascade GO:0043410 17 16 0,000 0,09977443 0,13219574 ! regulation of microtubule cytoskeleton organization GO:0070507 16 16 0,000 0,09977443 0,13210077 ! cofactor catabolic process GO:0051187 16 16 0,000 0,09977443 0,13200594 ! ethanolamine and derivative metabolic process GO:0042439 17 16 0,000 0,09977443 0,13191125 ! polyol metabolic process GO:0019751 16 16 0,000 0,09977443 0,13181669 ! serine family amino acid metabolic process GO:0009069 16 16 0,000 0,09977443 0,13172226 ! glutamine family amino acid catabolic process GO:0009065 17 16 0,000 0,09977443 0,13162797 ! porphyrin metabolic process GO:0006778 16 16 0,000 0,09977443 0,13153382 GO:0033013|tetrapyrrole metabolic process, ! embryonic epithelial tube formation GO:0001838 17 16 0,000 0,09977443 0,1314398 GO:0001841|neural tube formation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 17 16 0,000 0,09977443 0,13134591 ! regulation of coagulation GO:0050818 17 16 0,000 0,09977443 0,13125216 ! cellular amino acid derivative metabolic process GO:0006575 87 84 1,000 0,10417215 0,13693956 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 17 17 0,000 0,10567626 0,13881778 ! regulation of actin filament depolymerization GO:0030834 17 17 0,000 0,10567626 0,13871891 ! phosphoinositide biosynthetic process GO:0046489 17 17 0,000 0,10567626 0,13862018 ! regulation of transmembrane transport GO:0034762 17 17 0,000 0,10567626 0,13852158 ! nucleotide-excision repair, DNA damage removal GO:0000718 18 17 0,000 0,10567626 0,13842313 ! leukocyte adhesion GO:0007159 17 17 0,000 0,10567626 0,13832482 ! sensory perception of smell GO:0007608 17 17 0,000 0,10567626 0,13822665 ! glucose transport GO:0015758 17 17 0,000 0,10567626 0,13812861 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 17 17 0,000 0,10567626 0,13803072 ! embryonic skeletal system morphogenesis GO:0048704 17 17 0,000 0,10567626 0,13793296 ! cellular carbohydrate biosynthetic process GO:0034637 17 17 0,000 0,10567626 0,13783535 ! development of primary male sexual characteristics GO:0046546 17 17 0,000 0,10567626 0,13773787 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 17 17 0,000 0,10567626 0,13764053 ! neural crest cell development GO:0014032 19 17 0,000 0,10567626 0,13754332 GO:0014033|neural crest cell differentiation, ! immune response-activating signal transduction GO:0002757 17 17 0,000 0,10567626 0,13744626 GO:0002764|immune response-regulating signal transduction, ! cell recognition GO:0008037 18 17 0,000 0,10567626 0,13734933 ! positive regulation of protein secretion GO:0050714 17 17 0,000 0,10567626 0,13725253 ! regulation of osteoblast differentiation GO:0045667 17 17 0,000 0,10567626 0,13715588 ! pyridine nucleotide metabolic process GO:0019362 17 17 0,000 0,10567626 0,13705936 ! pigmentation GO:0043473 17 17 0,000 0,10567626 0,13696297 ! adult locomotory behavior GO:0008344 17 17 0,000 0,10567626 0,13686672 ! embryonic organ development GO:0048568 17 17 0,000 0,10567626 0,13677061 ! regulation of calcium ion transport GO:0051924 17 17 0,000 0,10567626 0,13667463 ! gene silencing GO:0016458 17 17 0,000 0,10567626 0,13657878 ! positive regulation of response to stimulus GO:0048584 86 85 1,000 0,10625378 0,13722896 ! heart development GO:0007507 90 87 1,000 0,11045118 0,14255009 ! mRNA export from nucleus GO:0006406 18 18 0,000 0,11154025 0,14385492 ! regulation of cellular catabolic process GO:0031329 18 18 0,000 0,11154025 0,14375432 ! icosanoid biosynthetic process GO:0046456 18 18 0,000 0,11154025 0,14365387 ! meiosis I GO:0007127 18 18 0,000 0,11154025 0,14355355 ! regulation of metal ion transport GO:0010959 18 18 0,000 0,11154025 0,14345337 ! membrane docking GO:0022406 18 18 0,000 0,11154025 0,14335333 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 18 18 0,000 0,11154025 0,14325344 ! mononuclear cell proliferation GO:0032943 18 18 0,000 0,11154025 0,14315368 GO:0070661|leukocyte proliferation, ! response to calcium ion GO:0051592 18 18 0,000 0,11154025 0,14305406 ! negative regulation of response to external stimulus GO:0032102 18 18 0,000 0,11154025 0,14295458 ! hexose transport GO:0008645 18 18 0,000 0,11154025 0,14285523 GO:0015749|monosaccharide transport, ! cholesterol homeostasis GO:0042632 18 18 0,000 0,11154025 0,14275603 GO:0055092|sterol homeostasis, ! striated muscle contraction GO:0006941 18 18 0,000 0,11154025 0,14265696 ! neutral lipid metabolic process GO:0006638 18 18 0,000 0,11154025 0,14255803 GO:0006639|acylglycerol metabolic process, ! ceramide metabolic process GO:0006672 18 18 0,000 0,11154025 0,14245924 GO:0046519|sphingoid metabolic process, ! ribonucleoside monophosphate metabolic process GO:0009161 18 18 0,000 0,11154025 0,14236058 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! telencephalon development GO:0021537 19 18 0,000 0,11154025 0,14226206 ! hexose biosynthetic process GO:0019319 18 18 0,000 0,11154025 0,14216368 ! negative regulation of MAP kinase activity GO:0043407 18 18 0,000 0,11154025 0,14206543 ! BMP signaling pathway GO:0030509 18 18 0,000 0,11154025 0,14196732 ! regulation of microtubule-based process GO:0032886 18 18 0,000 0,11154025 0,14186934 ! symbiosis, encompassing mutualism through parasitism GO:0044403 18 18 0,000 0,11154025 0,1417715 ! establishment of vesicle localization GO:0051650 19 18 0,000 0,11154025 0,1416738 ! chemotaxis GO:0006935 90 89 1,000 0,11469255 0,14557739 GO:0042330|taxis, ! regulation of Ras protein signal transduction GO:0046578 90 90 1,000 0,11682917 0,14818731 ! activation of adenylate cyclase activity GO:0007190 19 19 0,000 0,11736664 0,14876666 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 19 19 0,000 0,11736664 0,14866441 GO:0006956|complement activation, ! glial cell differentiation GO:0010001 19 19 0,000 0,11736664 0,14856231 ! feeding behavior GO:0007631 19 19 0,000 0,11736664 0,14846034 ! peroxisome organization GO:0007031 19 19 0,000 0,11736664 0,14835852 ! positive regulation of T cell proliferation GO:0042102 19 19 0,000 0,11736664 0,14825683 ! regulation of striated muscle tissue development GO:0016202 20 19 0,000 0,11736664 0,14815529 ! metanephros development GO:0001656 19 19 0,000 0,11736664 0,14805388 ! ribonucleoside metabolic process GO:0009119 19 19 0,000 0,11736664 0,14795261 ! regulation of lymphocyte mediated immunity GO:0002706 19 19 0,000 0,11736664 0,14785148 ! positive regulation of T cell differentiation GO:0045582 19 19 0,000 0,11736664 0,14775049 ! nuclear-transcribed mRNA catabolic process GO:0000956 19 19 0,000 0,11736664 0,14764964 ! hormone biosynthetic process GO:0042446 19 19 0,000 0,11736664 0,14754892 ! biogenic amine biosynthetic process GO:0042401 20 19 0,000 0,11736664 0,14744834 ! eye morphogenesis GO:0048592 19 19 0,000 0,11736664 0,1473479 ! vesicle localization GO:0051648 20 19 0,000 0,11736664 0,1472476 ! fatty acid metabolic process GO:0006631 93 92 1,000 0,12113315 0,15186966 ! positive regulation of immune system process GO:0002684 92 92 1,000 0,12113315 0,15176642 ! regulation of muscle development GO:0048634 21 20 0,000 0,12315567 0,15419558 ! establishment or maintenance of cell polarity GO:0007163 21 20 0,000 0,12315567 0,1540909 ! organic ether metabolic process GO:0018904 20 20 0,000 0,12315567 0,15398636 GO:0006662|glycerol ether metabolic process, ! cytoskeleton-dependent intracellular transport GO:0030705 20 20 0,000 0,12315567 0,15388196 ! neural tube development GO:0021915 21 20 0,000 0,12315567 0,1537777 ! phagocytosis GO:0006909 21 20 0,000 0,12315567 0,15367359 ! unsaturated fatty acid biosynthetic process GO:0006636 20 20 0,000 0,12315567 0,15356962 ! protein targeting to membrane GO:0006612 22 20 0,000 0,12315567 0,15346578 ! cyclic nucleotide metabolic process GO:0009187 20 20 0,000 0,12315567 0,15336209 ! chromatin remodeling GO:0006338 20 20 0,000 0,12315567 0,15325854 ! detection of abiotic stimulus GO:0009582 21 20 0,000 0,12315567 0,15315512 ! lipid oxidation GO:0034440 20 20 0,000 0,12315567 0,15305185 GO:0019395|fatty acid oxidation, ! female gamete generation GO:0007292 20 20 0,000 0,12315567 0,15294871 ! negative regulation of neuron apoptosis GO:0043524 21 20 0,000 0,12315567 0,15284572 ! monosaccharide biosynthetic process GO:0046364 20 20 0,000 0,12315567 0,15274286 ! RNA modification GO:0009451 20 20 0,000 0,12315567 0,15264014 ! single fertilization GO:0007338 21 20 0,000 0,12315567 0,15253756 ! regulation of B cell activation GO:0050864 20 20 0,000 0,12315567 0,15243512 ! pattern specification process GO:0007389 96 94 1,000 0,1254767 0,15520373 ! epidermis development GO:0008544 94 94 1,000 0,1254767 0,15509963 ! mitotic sister chromatid segregation GO:0000070 21 21 0,000 0,12890756 0,15923367 ! mRNA catabolic process GO:0006402 21 21 0,000 0,12890756 0,15912701 ! positive regulation of adenylate cyclase activity GO:0045762 21 21 0,000 0,12890756 0,1590205 GO:0051349|positive regulation of lyase activity, GO:0031281|positive regulation of cyclase activity, ! protein amino acid lipidation GO:0006497 21 21 0,000 0,12890756 0,15891414 ! receptor-mediated endocytosis GO:0006898 21 21 0,000 0,12890756 0,15880791 ! Notch signaling pathway GO:0007219 22 21 0,000 0,12890756 0,15870183 ! morphogenesis of embryonic epithelium GO:0016331 22 21 0,000 0,12890756 0,15859588 ! ear morphogenesis GO:0042471 21 21 0,000 0,12890756 0,15849008 ! organic anion transport GO:0015711 21 21 0,000 0,12890756 0,15838442 ! cholesterol transport GO:0030301 21 21 0,000 0,12890756 0,1582789 GO:0015918|sterol transport, ! spliceosome assembly GO:0000245 22 21 0,000 0,12890756 0,15817352 ! regulation of Rab protein signal transduction GO:0032483 21 21 0,000 0,12890756 0,15806828 GO:0032313|regulation of Rab GTPase activity, ! regulation of leukocyte mediated immunity GO:0002703 21 21 0,000 0,12890756 0,15796319 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 21 21 0,000 0,12890756 0,15785823 ! cellular response to insulin stimulus GO:0032869 23 21 0,000 0,12890756 0,15775341 ! endocytosis GO:0006897 99 98 1,000 0,13427569 0,16421374 GO:0010324|membrane invagination, ! blood circulation GO:0008015 99 98 1,000 0,13427569 0,16410484 GO:0003013|circulatory system process, ! regulation of system process GO:0044057 98 98 1,000 0,13427569 0,16399609 ! positive regulation of transcription factor activity GO:0051091 22 22 0,000 0,13462256 0,16431084 GO:0090047|positive regulation of transcription regulator activity, ! RNA export from nucleus GO:0006405 22 22 0,000 0,13462256 0,1642021 ! positive regulation of DNA metabolic process GO:0051054 23 22 0,000 0,13462256 0,1640935 ! sister chromatid segregation GO:0000819 22 22 0,000 0,13462256 0,16398504 ! regulation of ion transport GO:0043269 22 22 0,000 0,13462256 0,16387673 ! odontogenesis GO:0042476 22 22 0,000 0,13462256 0,16376856 ! positive regulation of lymphocyte proliferation GO:0050671 22 22 0,000 0,13462256 0,16366053 GO:0032946|positive regulation of mononuclear cell proliferation, GO:0070665|positive regulation of leukocyte proliferation, GO:0070668|positive regulation of mast cell proliferation, ! hormone-mediated signaling GO:0009755 22 22 0,000 0,13462256 0,16355265 ! embryonic skeletal system development GO:0048706 22 22 0,000 0,13462256 0,16344491 ! ovulation cycle process GO:0022602 22 22 0,000 0,13462256 0,16333731 ! spindle organization GO:0007051 22 22 0,000 0,13462256 0,16322985 ! pigment biosynthetic process GO:0046148 22 22 0,000 0,13462256 0,16312253 ! cell chemotaxis GO:0060326 23 22 0,000 0,13462256 0,16301536 GO:0030595|leukocyte chemotaxis, ! respiratory gaseous exchange GO:0007585 22 22 0,000 0,13462256 0,16290832 ! male sex differentiation GO:0046661 22 22 0,000 0,13462256 0,16280142 ! sterol biosynthetic process GO:0016126 22 22 0,000 0,13462256 0,16269467 ! regulation of adaptive immune response GO:0002819 22 22 0,000 0,13462256 0,16258805 ! detection of external stimulus GO:0009581 23 22 0,000 0,13462256 0,16248158 ! neuron migration GO:0001764 22 22 0,000 0,13462256 0,16237524 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 22 22 0,000 0,13462256 0,16226905 ! positive regulation of lymphocyte differentiation GO:0045621 22 22 0,000 0,13462256 0,16216299 ! fatty acid catabolic process GO:0009062 23 22 0,000 0,13462256 0,16205707 ! aerobic respiration GO:0009060 22 22 0,000 0,13462256 0,16195129 ! cytokine production GO:0001816 22 22 0,000 0,13462256 0,16184564 ! anti-apoptosis GO:0006916 100 99 1,000 0,13649755 0,16399282 ! ectoderm development GO:0007398 99 99 1,000 0,13649755 0,16388598 ! response to hydrogen peroxide GO:0042542 24 23 0,000 0,14030089 0,16834279 ! epithelial cell differentiation GO:0030855 23 23 0,000 0,14030089 0,16823327 ! regulation of hormone secretion GO:0046883 23 23 0,000 0,14030089 0,16812388 ! response to estrogen stimulus GO:0043627 23 23 0,000 0,14030089 0,16801464 ! negative regulation of protein complex disassembly GO:0043242 23 23 0,000 0,14030089 0,16790554 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 23 23 0,000 0,14030089 0,16779658 ! regulation of ARF protein signal transduction GO:0032012 23 23 0,000 0,14030089 0,16768776 ! endocrine system development GO:0035270 23 23 0,000 0,14030089 0,16757909 ! lipoprotein biosynthetic process GO:0042158 23 23 0,000 0,14030089 0,16747055 ! female gonad development GO:0008585 23 23 0,000 0,14030089 0,16736216 ! lipid homeostasis GO:0055088 23 23 0,000 0,14030089 0,1672539 ! Rho protein signal transduction GO:0007266 24 23 0,000 0,14030089 0,16714579 ! cell projection assembly GO:0030031 25 23 0,000 0,14030089 0,16703781 ! gliogenesis GO:0042063 24 24 0,000 0,14594278 0,1736427 ! cellular amino acid biosynthetic process GO:0008652 24 24 0,000 0,14594278 0,17353067 ! glucose homeostasis GO:0042593 24 24 0,000 0,14594278 0,17341879 GO:0033500|carbohydrate homeostasis, ! heterocycle biosynthetic process GO:0018130 24 24 0,000 0,14594278 0,17330705 ! nucleotide catabolic process GO:0009166 24 24 0,000 0,14594278 0,17319545 ! ovulation cycle GO:0042698 24 24 0,000 0,14594278 0,173084 ! fertilization GO:0009566 25 24 0,000 0,14594278 0,1729727 ! oxidoreduction coenzyme metabolic process GO:0006733 24 24 0,000 0,14594278 0,17286153 ! epithelial tube morphogenesis GO:0060562 25 24 0,000 0,14594278 0,17275051 ! glucan metabolic process GO:0044042 25 24 0,000 0,14594278 0,17263963 GO:0006073|cellular glucan metabolic process, GO:0005977|glycogen metabolic process, ! regulation of actin filament polymerization GO:0030833 25 25 0,000 0,15154846 0,17915575 ! negative regulation of secretion GO:0051048 26 25 0,000 0,15154846 0,17904091 ! protein amino acid N-linked glycosylation GO:0006487 25 25 0,000 0,15154846 0,17892621 ! sensory perception of chemical stimulus GO:0007606 25 25 0,000 0,15154846 0,17881166 ! cellular component disassembly GO:0022411 26 25 0,000 0,15154846 0,17869726 ! alcohol biosynthetic process GO:0046165 25 25 0,000 0,15154846 0,178583 ! development of primary female sexual characteristics GO:0046545 25 25 0,000 0,15154846 0,17846889 GO:0046660|female sex differentiation, ! polysaccharide biosynthetic process GO:0000271 25 25 0,000 0,15154846 0,17835493 ! excretion GO:0007588 25 25 0,000 0,15154846 0,17824111 ! positive regulation of DNA binding GO:0043388 26 25 0,000 0,15154846 0,17812743 ! generation of a signal involved in cell-cell signaling GO:0003001 27 25 0,000 0,15154846 0,17801391 ! gastrulation GO:0007369 25 25 0,000 0,15154846 0,17790052 ! heart morphogenesis GO:0003007 25 25 0,000 0,15154846 0,17778728 ! icosanoid metabolic process GO:0006690 25 25 0,000 0,15154846 0,17767418 ! regulation of endocytosis GO:0030100 25 25 0,000 0,15154846 0,17756123 ! positive regulation of cytokine production GO:0001819 25 25 0,000 0,15154846 0,17744842 ! positive regulation of binding GO:0051099 27 26 0,000 0,15711817 0,18385319 ! positive regulation of defense response GO:0031349 26 26 0,000 0,15711817 0,18373654 ! glycolysis GO:0006096 26 26 0,000 0,15711817 0,18362003 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 26 26 0,000 0,15711817 0,18350366 ! negative regulation of cell migration GO:0030336 26 26 0,000 0,15711817 0,18338745 ! cellular defense response GO:0006968 26 26 0,000 0,15711817 0,18327138 ! positive regulation of cytokine biosynthetic process GO:0042108 26 26 0,000 0,15711817 0,18315546 ! regulation of protein secretion GO:0050708 26 26 0,000 0,15711817 0,18303969 ! germ cell development GO:0007281 27 26 0,000 0,15711817 0,18292406 ! regulation of blood vessel size GO:0050880 27 26 0,000 0,15711817 0,18280857 GO:0035150|regulation of tube size, ! pigment metabolic process GO:0042440 26 26 0,000 0,15711817 0,18269324 ! response to insulin stimulus GO:0032868 28 26 0,000 0,15711817 0,18257805 ! chloride transport GO:0006821 27 27 0,000 0,16265212 0,18888963 ! regulation of neurotransmitter levels GO:0001505 31 27 0,000 0,16265212 0,18877069 ! energy reserve metabolic process GO:0006112 28 27 0,000 0,16265212 0,18865189 ! learning or memory GO:0007611 28 27 0,000 0,16265212 0,18853324 ! monocarboxylic acid transport GO:0015718 27 27 0,000 0,16265212 0,18841474 ! peptide metabolic process GO:0006518 29 27 0,000 0,16265212 0,18829639 ! inner ear development GO:0048839 27 27 0,000 0,16265212 0,18817819 ! defense response to bacterium GO:0042742 27 27 0,000 0,16265212 0,18806013 ! isoprenoid metabolic process GO:0006720 27 27 0,000 0,16265212 0,18794222 ! cell growth GO:0016049 27 27 0,000 0,16265212 0,18782447 ! tRNA aminoacylation for protein translation GO:0006418 28 28 0,000 0,16815053 0,19405224 GO:0043038|amino acid activation, GO:0043039|tRNA aminoacylation, ! neuromuscular process GO:0050905 28 28 0,000 0,16815053 0,19393081 ! carbohydrate transport GO:0008643 28 28 0,000 0,16815053 0,19380953 ! regulation of muscle contraction GO:0006937 28 28 0,000 0,16815053 0,1936884 ! unsaturated fatty acid metabolic process GO:0033559 28 28 0,000 0,16815053 0,19356742 ! sulfur compound biosynthetic process GO:0044272 28 28 0,000 0,16815053 0,19344659 ! keratinocyte differentiation GO:0030216 28 28 0,000 0,16815053 0,19332591 ! histone modification GO:0016570 28 28 0,000 0,16815053 0,19320538 ! developmental growth GO:0048589 28 28 0,000 0,16815053 0,193085 ! glycerophospholipid biosynthetic process GO:0046474 30 29 0,000 0,17361364 0,19923409 ! phosphoinositide metabolic process GO:0030384 29 29 0,000 0,17361364 0,19911011 ! leukocyte migration GO:0050900 30 29 0,000 0,17361364 0,19898628 ! branching morphogenesis of a tube GO:0048754 29 29 0,000 0,17361364 0,19886261 ! antigen processing and presentation GO:0019882 29 29 0,000 0,17361364 0,1987391 ! tRNA processing GO:0008033 29 29 0,000 0,17361364 0,19861573 ! covalent chromatin modification GO:0016569 29 29 0,000 0,17361364 0,19849252 ! adult behavior GO:0030534 30 29 0,000 0,17361364 0,19836946 ! regulation of protein polymerization GO:0032271 29 29 0,000 0,17361364 0,19824656 ! transition metal ion transport GO:0000041 31 30 0,000 0,17904167 0,20431814 ! RNA catabolic process GO:0006401 30 30 0,000 0,17904167 0,2041917 ! ER to Golgi vesicle-mediated transport GO:0006888 30 30 0,000 0,17904167 0,20406542 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 30 30 0,000 0,17904167 0,2039393 ! neuropeptide signaling pathway GO:0007218 30 30 0,000 0,17904167 0,20381334 ! regulation of protein complex disassembly GO:0043244 30 30 0,000 0,17904167 0,20368752 ! regulation of ossification GO:0030278 30 30 0,000 0,17904167 0,20356187 ! immunoglobulin mediated immune response GO:0016064 30 30 0,000 0,17904167 0,20343637 GO:0019724|B cell mediated immunity, ! regulation of inflammatory response GO:0050727 30 30 0,000 0,17904167 0,20331102 ! water-soluble vitamin metabolic process GO:0006767 30 30 0,000 0,17904167 0,20318583 ! vesicle organization GO:0016050 30 30 0,000 0,17904167 0,20306079 ! cellular amino acid derivative biosynthetic process GO:0042398 31 30 0,000 0,17904167 0,20293591 ! establishment of organelle localization GO:0051656 31 30 0,000 0,17904167 0,20281118 ! regulation of translational initiation GO:0006446 31 31 0,000 0,18443482 0,208792 ! membrane fusion GO:0006944 31 31 0,000 0,18443482 0,20866383 ! negative regulation of cytoskeleton organization GO:0051494 32 31 0,000 0,18443482 0,20853581 ! lipoprotein metabolic process GO:0042157 31 31 0,000 0,18443482 0,20840796 ! ion transmembrane transport GO:0034220 31 31 0,000 0,18443482 0,20828026 GO:0015985|energy coupled proton transport, down electrochemical gradient, GO:0015986|ATP synthesis coupled proton transport, ! glycerolipid biosynthetic process GO:0045017 32 31 0,000 0,18443482 0,20815271 ! digestion GO:0007586 31 31 0,000 0,18443482 0,20802532 ! nucleoside metabolic process GO:0009116 31 31 0,000 0,18443482 0,20789809 ! regulation of heart contraction GO:0008016 31 31 0,000 0,18443482 0,20777101 ! sphingolipid metabolic process GO:0006665 31 31 0,000 0,18443482 0,20764409 ! camera-type eye development GO:0043010 31 31 0,000 0,18443482 0,20751732 ! extracellular matrix organization GO:0030198 31 31 0,000 0,18443482 0,20739071 ! ribonucleoprotein complex assembly GO:0022618 32 31 0,000 0,18443482 0,20726425 ! epidermal cell differentiation GO:0009913 31 31 0,000 0,18443482 0,20713795 ! negative regulation of cell motion GO:0051271 31 31 0,000 0,18443482 0,2070118 ! cell redox homeostasis GO:0045454 32 32 0,000 0,18979333 0,2128966 ! glucose catabolic process GO:0006007 32 32 0,000 0,18979333 0,2127671 ! lipid modification GO:0030258 32 32 0,000 0,18979333 0,21263776 ! glycosaminoglycan metabolic process GO:0030203 34 32 0,000 0,18979333 0,21250857 ! regulation of vesicle-mediated transport GO:0060627 33 32 0,000 0,18979333 0,21237955 ! morphogenesis of a branching structure GO:0001763 32 32 0,000 0,18979333 0,21225067 ! nuclear export GO:0051168 32 32 0,000 0,18979333 0,21212196 ! kidney development GO:0001822 32 32 0,000 0,18979333 0,2119934 ! protein maturation by peptide bond cleavage GO:0051605 32 32 0,000 0,18979333 0,211865 ! amino acid transport GO:0006865 33 33 0,000 0,19511741 0,21767639 ! regulation of protein complex assembly GO:0043254 33 33 0,000 0,19511741 0,2175447 ! membrane lipid metabolic process GO:0006643 33 33 0,000 0,19511741 0,21741317 ! regulation of actin polymerization or depolymerization GO:0008064 33 33 0,000 0,19511741 0,21728181 ! regulation of actin filament length GO:0030832 34 34 0,000 0,20040728 0,22303781 ! ear development GO:0043583 34 34 0,000 0,20040728 0,22290321 ! cellular polysaccharide metabolic process GO:0044264 35 34 0,000 0,20040728 0,22276877 ! coenzyme biosynthetic process GO:0009108 34 34 0,000 0,20040728 0,22263449 ! nucleoside monophosphate biosynthetic process GO:0009124 34 34 0,000 0,20040728 0,22250037 ! secondary metabolic process GO:0019748 34 34 0,000 0,20040728 0,22236641 ! response to peptide hormone stimulus GO:0043434 36 34 0,000 0,20040728 0,22223262 ! negative regulation of response to stimulus GO:0048585 34 34 0,000 0,20040728 0,22209899 ! detection of stimulus GO:0051606 36 34 0,000 0,20040728 0,22196551 ! acute inflammatory response GO:0002526 35 35 0,000 0,20566315 0,22764996 ! regulation of cellular component size GO:0032535 35 35 0,000 0,20566315 0,22751331 ! regulation of cytokine biosynthetic process GO:0042035 35 35 0,000 0,20566315 0,22737683 ! mesoderm development GO:0007498 35 35 0,000 0,20566315 0,22724052 ! multicellular organism reproduction GO:0032504 36 35 0,000 0,20566315 0,22710436 GO:0048609|reproductive process in a multicellular organism, ! inorganic anion transport GO:0015698 35 35 0,000 0,20566315 0,22696837 ! response to steroid hormone stimulus GO:0048545 35 35 0,000 0,20566315 0,22683254 ! regulation of immune effector process GO:0002697 35 35 0,000 0,20566315 0,22669688 ! hydrogen transport GO:0006818 36 36 0,000 0,21088523 0,23231409 GO:0015992|proton transport, ! aminoglycan metabolic process GO:0006022 38 36 0,000 0,21088523 0,23217532 ! oxygen and reactive oxygen species metabolic process GO:0006800 37 36 0,000 0,21088523 0,2320367 ! embryonic limb morphogenesis GO:0030326 36 36 0,000 0,21088523 0,23189826 GO:0035113|embryonic appendage morphogenesis, ! female pregnancy GO:0007565 37 36 0,000 0,21088523 0,23175998 ! RNA elongation from RNA polymerase II promoter GO:0006368 36 36 0,000 0,21088523 0,23162186 ! positive regulation of organelle organization GO:0010638 36 36 0,000 0,21088523 0,23148391 ! heterocycle catabolic process GO:0046700 36 36 0,000 0,21088523 0,23134612 ! gonad development GO:0008406 36 36 0,000 0,21088523 0,23120849 ! activation of immune response GO:0002253 36 36 0,000 0,21088523 0,23107103 ! meiosis GO:0007126 37 37 0,000 0,21607374 0,23661551 GO:0051327|M phase of meiotic cell cycle, ! lymphocyte mediated immunity GO:0002449 37 37 0,000 0,21607374 0,236475 ! eye development GO:0001654 37 37 0,000 0,21607374 0,23633466 ! ATP synthesis coupled electron transport GO:0042773 37 37 0,000 0,21607374 0,23619449 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! cellular amino acid catabolic process GO:0009063 38 37 0,000 0,21607374 0,23605448 ! positive regulation of secretion GO:0051047 39 38 0,000 0,22122889 0,24154315 ! neurotransmitter transport GO:0006836 40 38 0,000 0,22122889 0,24140014 ! cellular hormone metabolic process GO:0034754 39 38 0,000 0,22122889 0,2412573 ! exocytosis GO:0006887 40 38 0,000 0,22122889 0,24111463 ! urogenital system development GO:0001655 38 38 0,000 0,22122889 0,24097213 ! hexose catabolic process GO:0019320 38 38 0,000 0,22122889 0,24082979 ! RNA elongation GO:0006354 38 38 0,000 0,22122889 0,24068763 ! meiotic cell cycle GO:0051321 38 38 0,000 0,22122889 0,24054563 ! response to unfolded protein GO:0006986 39 39 0,000 0,22635089 0,24596974 ! nucleoside monophosphate metabolic process GO:0009123 39 39 0,000 0,22635089 0,2458248 ! fatty acid biosynthetic process GO:0006633 39 39 0,000 0,22635089 0,24568002 ! cytokine-mediated signaling pathway GO:0019221 39 39 0,000 0,22635089 0,24553542 ! intracellular protein transmembrane transport GO:0065002 39 39 0,000 0,22635089 0,24539099 ! positive regulation of T cell activation GO:0050870 39 39 0,000 0,22635089 0,24524673 ! limb development GO:0060173 39 39 0,000 0,22635089 0,24510263 GO:0048736|appendage development, GO:0035107|appendage morphogenesis, ! DNA catabolic process GO:0006308 41 40 0,000 0,23143994 0,25046612 ! organelle localization GO:0051640 41 40 0,000 0,23143994 0,25031913 ! amine catabolic process GO:0009310 42 41 0,000 0,23649625 0,25563789 ! elevation of cytosolic calcium ion concentration GO:0007204 41 41 0,000 0,23649625 0,25548804 ! phospholipid biosynthetic process GO:0008654 42 41 0,000 0,23649625 0,25533837 ! leukocyte mediated immunity GO:0002443 41 41 0,000 0,23649625 0,25518887 ! regulation of Ras GTPase activity GO:0032318 41 41 0,000 0,23649625 0,25503955 ! monosaccharide catabolic process GO:0046365 41 41 0,000 0,23649625 0,25489041 ! respiratory electron transport chain GO:0022904 43 42 0,000 0,24152004 0,2601528 ! cytosolic calcium ion homeostasis GO:0051480 42 42 0,000 0,24152004 0,26000084 ! development of primary sexual characteristics GO:0045137 42 42 0,000 0,24152004 0,25984906 ! negative regulation of ligase activity GO:0051352 43 42 0,000 0,24152004 0,25969745 GO:0051444|negative regulation of ubiquitin-protein ligase activity, GO:0051436|negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle, ! response to protein stimulus GO:0051789 42 42 0,000 0,24152004 0,25954603 ! forebrain development GO:0030900 43 42 0,000 0,24152004 0,25939477 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 42 42 0,000 0,24152004 0,2592437 ! reproductive structure development GO:0048608 43 43 0,000 0,2465115 0,26444743 ! alcohol catabolic process GO:0046164 43 43 0,000 0,2465115 0,2642936 ! humoral immune response GO:0006959 44 44 0,000 0,25147084 0,26945392 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 45 44 0,000 0,25147084 0,26929736 ! mRNA transport GO:0051028 44 44 0,000 0,25147084 0,26914097 ! negative regulation of organelle organization GO:0010639 45 44 0,000 0,25147084 0,26898476 ! vitamin metabolic process GO:0006766 44 44 0,000 0,25147084 0,26882874 ! positive regulation of lymphocyte activation GO:0051251 44 44 0,000 0,25147084 0,2686729 ! amine biosynthetic process GO:0009309 46 45 0,000 0,25639825 0,27377867 ! regulation of actin cytoskeleton organization GO:0032956 46 45 0,000 0,25639825 0,27362014 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 46 45 0,000 0,25639825 0,27346179 ! steroid biosynthetic process GO:0006694 46 45 0,000 0,25639825 0,27330363 ! protein processing GO:0016485 45 45 0,000 0,25639825 0,27314565 ! regulation of actin filament-based process GO:0032970 47 46 0,000 0,26129395 0,27820031 ! tube morphogenesis GO:0035239 47 46 0,000 0,26129395 0,27803969 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 47 46 0,000 0,26129395 0,27787925 ! transcription initiation from RNA polymerase II promoter GO:0006367 46 46 0,000 0,26129395 0,277719 ! positive regulation of ligase activity GO:0051351 47 46 0,000 0,26129395 0,27755893 ! regulation of blood pressure GO:0008217 48 47 0,000 0,26615812 0,28256303 ! sex differentiation GO:0007548 47 47 0,000 0,26615812 0,28240036 ! amine transport GO:0015837 47 47 0,000 0,26615812 0,28223787 ! rhythmic process GO:0048511 47 47 0,000 0,26615812 0,28207557 ! calcium ion transport GO:0006816 48 48 0,000 0,27099097 0,28703239 ! regulation of ubiquitin-protein ligase activity GO:0051438 49 48 0,000 0,27099097 0,28686753 ! glycerophospholipid metabolic process GO:0006650 49 48 0,000 0,27099097 0,28670285 ! cellular lipid catabolic process GO:0044242 50 49 0,000 0,2757927 0,29161558 ! divalent metal ion transport GO:0070838 49 49 0,000 0,2757927 0,29144837 ! response to nutrient GO:0007584 49 49 0,000 0,2757927 0,29128135 ! response to bacterium GO:0009617 50 49 0,000 0,2757927 0,29111452 ! regulation of ligase activity GO:0051340 50 49 0,000 0,2757927 0,29094788 ! cofactor biosynthetic process GO:0051188 49 49 0,000 0,2757927 0,29078144 ! positive regulation of cell activation GO:0050867 49 49 0,000 0,2757927 0,29061518 GO:0002696|positive regulation of leukocyte activation, ! regulation of defense response GO:0031347 50 50 0,000 0,2805635 0,29547345 ! chromatin assembly GO:0031497 50 50 0,000 0,2805635 0,2953047 GO:0006334|nucleosome assembly, ! RNA transport GO:0050658 50 50 0,000 0,2805635 0,29513615 GO:0050657|nucleic acid transport, GO:0051236|establishment of RNA localization, ! nitrogen compound catabolic process GO:0044270 51 50 0,000 0,2805635 0,29496779 ! transcription initiation GO:0006352 50 50 0,000 0,2805635 0,29479962 ! anterior/posterior pattern formation GO:0009952 51 50 0,000 0,2805635 0,29463164 ! biogenic amine metabolic process GO:0006576 52 51 0,000 0,28530357 0,29943877 ! positive regulation of immune response GO:0050778 51 51 0,000 0,28530357 0,29926834 ! rRNA metabolic process GO:0016072 51 51 0,000 0,28530357 0,29909811 GO:0006364|rRNA processing, ! protein-DNA complex assembly GO:0065004 51 51 0,000 0,28530357 0,29892807 ! ATP biosynthetic process GO:0006754 51 51 0,000 0,28530357 0,29875822 ! protein maturation GO:0051604 51 51 0,000 0,28530357 0,29858857 ! RNA localization GO:0006403 52 52 0,000 0,29001309 0,30334513 ! cholesterol metabolic process GO:0008203 52 52 0,000 0,29001309 0,30317307 ! regulation of GTPase activity GO:0043087 53 52 0,000 0,29001309 0,3030012 ! sodium ion transport GO:0006814 53 53 0,000 0,29469227 0,30771549 ! tRNA metabolic process GO:0006399 53 53 0,000 0,29469227 0,30754125 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 53 53 0,000 0,29469227 0,3073672 ! carbohydrate biosynthetic process GO:0016051 53 53 0,000 0,29469227 0,30719335 ! carbohydrate catabolic process GO:0016052 53 53 0,000 0,29469227 0,3070197 ! response to virus GO:0009615 54 54 0,000 0,29934128 0,311687 ! hormone metabolic process GO:0042445 55 54 0,000 0,29934128 0,311511 ! nucleosome organization GO:0034728 55 55 0,000 0,30396034 0,31613933 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 55 55 0,000 0,30396034 0,31596103 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! microtubule cytoskeleton organization GO:0000226 55 55 0,000 0,30396034 0,31578292 ! ribonucleoside triphosphate biosynthetic process GO:0009201 56 56 0,000 0,30854961 0,3203701 ! reproductive developmental process GO:0003006 56 56 0,000 0,30854961 0,32018971 ! ATP metabolic process GO:0046034 57 57 0,000 0,31310929 0,32473856 ! nucleoside triphosphate biosynthetic process GO:0009142 57 57 0,000 0,31310929 0,32455592 ! innate immune response GO:0045087 58 58 0,000 0,31763957 0,32906673 ! carboxylic acid transport GO:0046942 59 59 0,000 0,32214062 0,33354223 GO:0015849|organic acid transport, ! sterol metabolic process GO:0016125 59 59 0,000 0,32214062 0,33335495 ! immune effector process GO:0002252 59 59 0,000 0,32214062 0,33316789 ! potassium ion transport GO:0006813 60 60 0,000 0,32661265 0,33760354 ! protein polymerization GO:0051258 65 60 0,000 0,32661265 0,3374143 ! cellular respiration GO:0045333 62 61 0,000 0,33105582 0,34181282 ! proteasomal protein catabolic process GO:0010498 62 61 0,000 0,33105582 0,34162143 GO:0043161|proteasomal ubiquitin-dependent protein catabolic process, ! carboxylic acid catabolic process GO:0046395 63 61 0,000 0,33105582 0,34143026 GO:0016054|organic acid catabolic process, ! lipid transport GO:0006869 62 62 0,000 0,33547032 0,3457896 ! purine ribonucleoside triphosphate metabolic process GO:0009205 62 62 0,000 0,33547032 0,34559631 ! morphogenesis of an epithelium GO:0002009 63 62 0,000 0,33547032 0,34540324 GO:0060429|epithelium development, ! di-, tri-valent inorganic cation transport GO:0015674 63 62 0,000 0,33547032 0,34521039 ! regulation of secretion GO:0051046 65 63 0,000 0,33985633 0,34952859 ! negative regulation of cellular component organization GO:0051129 65 63 0,000 0,33985633 0,34933364 ! glucose metabolic process GO:0006006 63 63 0,000 0,33985633 0,34913892 ! ribonucleoside triphosphate metabolic process GO:0009199 63 63 0,000 0,33985633 0,34894441 ! purine nucleoside triphosphate metabolic process GO:0009144 63 63 0,000 0,33985633 0,34875013 ! glycerolipid metabolic process GO:0046486 65 64 0,000 0,34421404 0,3530253 ! regulation of cytoskeleton organization GO:0051493 66 64 0,000 0,34421404 0,35282896 ! anion transport GO:0006820 65 65 0,000 0,34854361 0,3570683 ! regulation of hormone levels GO:0010817 66 65 0,000 0,34854361 0,35686993 ! protein amino acid glycosylation GO:0006486 66 66 0,000 0,35284523 0,36107371 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! nucleoside triphosphate metabolic process GO:0009141 66 66 0,000 0,35284523 0,36087334 ! polysaccharide metabolic process GO:0005976 69 66 0,000 0,35284523 0,36067319 ! Golgi vesicle transport GO:0048193 67 67 0,000 0,35711907 0,3648395 ! muscle contraction GO:0006936 67 67 0,000 0,35711907 0,36463737 ! purine ribonucleotide biosynthetic process GO:0009152 68 68 0,000 0,36136531 0,3687687 ! chromatin assembly or disassembly GO:0006333 68 68 0,000 0,36136531 0,36856462 ! regulation of translation GO:0006417 69 69 0,000 0,36558413 0,37266125 ! sensory perception of sound GO:0007605 71 69 0,000 0,36558413 0,37245525 GO:0050954|sensory perception of mechanical stimulus, ! growth GO:0040007 70 70 0,000 0,36977569 0,37651746 ! carboxylic acid biosynthetic process GO:0046394 70 70 0,000 0,36977569 0,37630955 GO:0016053|organic acid biosynthetic process, ! translational elongation GO:0006414 71 71 0,000 0,37394017 0,3803376 ! oxidative phosphorylation GO:0006119 71 71 0,000 0,37394017 0,38012781 ! calcium ion homeostasis GO:0055074 71 71 0,000 0,37394017 0,37991826 GO:0006874|cellular calcium ion homeostasis, ! ribosome biogenesis GO:0042254 71 71 0,000 0,37394017 0,37970894 ! secretion by cell GO:0032940 75 72 0,000 0,37807773 0,38369893 ! muscle system process GO:0003012 72 72 0,000 0,37807773 0,38348776 ! sensory organ development GO:0007423 72 72 0,000 0,37807773 0,38327682 ! regulation of cytokine production GO:0001817 72 72 0,000 0,37807773 0,38306611 ! electron transport chain GO:0022900 75 74 0,000 0,38627281 0,39115428 ! coenzyme metabolic process GO:0006732 75 74 0,000 0,38627281 0,39093948 ! ribonucleotide biosynthetic process GO:0009260 75 75 0,000 0,39033066 0,39482953 ! purine ribonucleotide metabolic process GO:0009150 75 75 0,000 0,39033066 0,39461295 ! cellular metal ion homeostasis GO:0006875 77 77 0,000 0,39836781 0,40251748 ! microtubule-based movement GO:0007018 82 78 0,000 0,40234745 0,40631581 ! metal ion homeostasis GO:0055065 78 78 0,000 0,40234745 0,40609329 ! regulation of immune response GO:0050776 78 78 0,000 0,40234745 0,40587102 ! glycoprotein biosynthetic process GO:0009101 80 80 0,000 0,41022965 0,41359587 ! lipid catabolic process GO:0016042 82 81 0,000 0,41413254 0,4173025 ! ribonucleotide metabolic process GO:0009259 83 83 0,000 0,42186271 0,42485955 ! ncRNA processing GO:0034470 83 83 0,000 0,42186271 0,42462751 ! organophosphate metabolic process GO:0019637 87 86 0,000 0,43327132 0,43587284 GO:0006644|phospholipid metabolic process, ! hexose metabolic process GO:0019318 87 86 0,000 0,43327132 0,43563504 ! purine nucleotide biosynthetic process GO:0006164 88 88 0,000 0,44075445 0,44291736 ! cellular di-, tri-valent inorganic cation homeostasis GO:0030005 89 89 0,000 0,4444597 0,4463974 ! brain development GO:0007420 91 90 0,000 0,44814094 0,44984954 ! di-, tri-valent inorganic cation homeostasis GO:0055066 91 91 0,000 0,45179833 0,45327399 ! visual perception GO:0007601 93 92 0,000 0,45543201 0,45667094 GO:0050953|sensory perception of light stimulus, ! energy derivation by oxidation of organic compounds GO:0015980 94 92 0,000 0,45543201 0,45642262 ! tissue morphogenesis GO:0048729 94 93 0,000 0,45904214 0,45979058 ! cofactor metabolic process GO:0051186 95 94 0,000 0,46262886 0,46313145 ! glycoprotein metabolic process GO:0009100 99 98 0,000 0,47674467 0,47700349 ! response to other organism GO:0051707 101 100 0,000 0,48366596 0,48366596