pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6685-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 4,000 2,936E-09 7,173E-06 ! induction of apoptosis by intracellular signals GO:0008629 95 45 5,000 2,516E-07 3,073E-04 ! negative regulation of phosphorylation GO:0042326 52 24 4,000 2,539E-07 2,068E-04 ! chondrocyte differentiation GO:0002062 27 11 3,000 3,641E-07 2,224E-04 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 4,000 3,892E-07 1,902E-04 GO:0045936|negative regulation of phosphate metabolic process, ! negative regulation of neuron differentiation GO:0045665 46 29 4,000 6,927E-07 2,821E-04 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 3,000 1,089E-06 3,801E-04 ! regulation of the force of heart contraction GO:0002026 31 15 3,000 1,479E-06 4,515E-04 ! neutrophil chemotaxis GO:0030593 29 17 3,000 2,554E-06 6,934E-04 ! negative regulation of protein kinase activity GO:0006469 144 69 5,000 3,295E-06 8,049E-04 ! negative regulation of kinase activity GO:0033673 145 70 5,000 3,586E-06 7,964E-04 ! myoblast cell fate commitment GO:0048625 18 6 2,000 3,9E-06 7,939E-04 ! establishment or maintenance of cell polarity GO:0007163 96 41 4,000 4,129E-06 7,759E-04 ! negative regulation of transferase activity GO:0051348 155 74 5,000 4,969E-06 8,671E-04 ! positive regulation of response to external stimulus GO:0032103 88 44 4,000 5,899E-06 9,607E-04 ! positive regulation of inflammatory response GO:0050729 41 21 3,000 6,307E-06 9,629E-04 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 2,000 6,795E-06 9,765E-04 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 4,000 7,375E-06 1,001E-03 ! inactivation of MAPK activity GO:0000188 45 22 3,000 7,673E-06 9,866E-04 ! positive regulation of locomotion GO:0040017 44 22 3,000 7,673E-06 9,372E-04 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! regulation of chemotaxis GO:0050920 45 23 3,000 9,246E-06 1,076E-03 ! male meiosis GO:0007140 9 8 2,000 1,082E-05 1,202E-03 ! positive regulation of insulin secretion GO:0032024 17 8 2,000 1,082E-05 1,15E-03 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 2,000 1,082E-05 1,102E-03 ! regulation of behavior GO:0050795 48 25 3,000 1,309E-05 1,279E-03 ! induction of positive chemotaxis GO:0050930 17 9 2,000 1,617E-05 1,519E-03 ! cell maturation GO:0048469 107 55 4,000 1,793E-05 1,623E-03 ! insulin receptor signaling pathway GO:0008286 66 27 3,000 1,799E-05 1,57E-03 ! negative regulation of protein modification process GO:0031400 66 28 3,000 2,089E-05 1,76E-03 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 2,000 2,3E-05 1,873E-03 ! interphase of mitotic cell cycle GO:0051329 224 98 5,000 2,513E-05 1,981E-03 ! forebrain development GO:0030900 210 98 5,000 2,513E-05 1,919E-03 ! negative regulation of transcription regulator activity GO:0090048 57 30 3,000 2,771E-05 2,051E-03 GO:0043433|negative regulation of transcription factor activity, ! regulation of heart contraction GO:0008016 123 61 4,000 2,981E-05 2,142E-03 ! regulation of smoothened signaling pathway GO:0008589 27 11 2,000 3,148E-05 2,198E-03 ! positive regulation of peptide secretion GO:0002793 24 11 2,000 3,148E-05 2,136E-03 ! neuroblast proliferation GO:0007405 25 11 2,000 3,148E-05 2,079E-03 ! negative regulation of glucose import GO:0046325 18 11 2,000 3,148E-05 2,024E-03 GO:0010829|negative regulation of glucose transport, ! cell junction assembly GO:0034329 85 31 3,000 3,167E-05 1,984E-03 ! leukocyte chemotaxis GO:0030595 55 33 3,000 4,081E-05 2,492E-03 GO:0060326|cell chemotaxis, ! regulation of positive chemotaxis GO:0050926 22 12 2,000 4,18E-05 2,49E-03 GO:0050927|positive regulation of positive chemotaxis, ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 2,000 4,18E-05 2,431E-03 ! regulation of hormone metabolic process GO:0032350 28 12 2,000 4,18E-05 2,375E-03 ! negative regulation of MAP kinase activity GO:0043407 78 34 3,000 4,604E-05 2,556E-03 ! developmental maturation GO:0021700 128 69 4,000 5,422E-05 2,943E-03 ! negative regulation of DNA binding GO:0043392 67 36 3,000 5,795E-05 3,077E-03 ! cell junction organization GO:0034330 96 37 3,000 6,467E-05 3,362E-03 ! actin filament organization GO:0007015 167 72 4,000 6,655E-05 3,387E-03 ! cell-cell junction assembly GO:0007043 32 14 2,000 6,856E-05 3,418E-03 ! cellular response to insulin stimulus GO:0032869 85 38 3,000 7,195E-05 3,516E-03 ! negative regulation of binding GO:0051100 71 39 3,000 7,981E-05 3,823E-03 ! carbohydrate homeostasis GO:0033500 59 39 3,000 7,981E-05 3,749E-03 GO:0042593|glucose homeostasis, ! regulation of transcription factor activity GO:0051090 137 75 4,000 8,093E-05 3,731E-03 GO:0090046|regulation of transcription regulator activity, ! phosphoinositide-mediated signaling GO:0048015 141 75 4,000 8,093E-05 3,661E-03 ! epithelial to mesenchymal transition GO:0001837 30 15 2,000 8,533E-05 3,79E-03 ! mammary gland development GO:0030879 93 40 3,000 8,827E-05 3,851E-03 ! positive regulation of protein import into nucleus GO:0042307 34 16 2,000 1,046E-04 4,482E-03 ! regulation of intracellular protein transport GO:0033157 86 42 3,000 1,071E-04 4,512E-03 ! epithelial cell differentiation GO:0030855 83 43 3,000 1,176E-04 4,868E-03 ! myoblast differentiation GO:0045445 50 17 2,000 1,264E-04 5,148E-03 ! regulation of epithelial cell proliferation GO:0050678 122 45 3,000 1,407E-04 5,633E-03 ! negative regulation of transport GO:0051051 164 85 4,000 1,467E-04 5,781E-03 ! regulation of neuron differentiation GO:0045664 187 85 4,000 1,467E-04 5,689E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 2,000 1,511E-04 5,766E-03 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 3,000 1,534E-04 5,764E-03 ! leukocyte migration GO:0050900 75 46 3,000 1,534E-04 5,676E-03 ! response to insulin stimulus GO:0032868 98 47 3,000 1,669E-04 6,084E-03 ! positive regulation of hormone secretion GO:0046887 35 19 2,000 1,786E-04 6,417E-03 ! positive regulation of cell cycle GO:0045787 96 48 3,000 1,812E-04 6,415E-03 ! positive regulation of defense response GO:0031349 88 48 3,000 1,812E-04 6,324E-03 ! regulation of inflammatory response GO:0050727 84 48 3,000 1,812E-04 6,234E-03 ! regulation of DNA binding GO:0051101 167 89 4,000 1,822E-04 6,181E-03 ! gland development GO:0048732 220 91 4,000 2,022E-04 6,766E-03 ! phosphoinositide phosphorylation GO:0046854 40 20 2,000 2,092E-04 6,907E-03 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 2,000 2,092E-04 6,815E-03 ! pancreas development GO:0031016 40 20 2,000 2,092E-04 6,725E-03 ! cell-cell junction organization GO:0045216 43 20 2,000 2,092E-04 6,638E-03 ! regulation of glucose import GO:0046324 30 20 2,000 2,092E-04 6,553E-03 GO:0010827|regulation of glucose transport, ! lipid phosphorylation GO:0046834 43 21 2,000 2,43E-04 7,516E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 2,000 2,43E-04 7,422E-03 ! regulation of vasoconstriction GO:0019229 40 21 2,000 2,43E-04 7,33E-03 ! cartilage development GO:0051216 99 53 3,000 2,665E-04 7,94E-03 ! regulation of DNA metabolic process GO:0051052 188 97 4,000 2,724E-04 8,017E-03 ! positive regulation of intracellular transport GO:0032388 42 22 2,000 2,802E-04 8,149E-03 ! embryonic skeletal system development GO:0048706 101 54 3,000 2,865E-04 8,235E-03 ! regulation of muscle contraction GO:0006937 94 54 3,000 2,865E-04 8,14E-03 ! response to UV GO:0009411 120 55 3,000 3,076E-04 8,638E-03 ! skeletal muscle tissue development GO:0007519 223 100 4,000 3,137E-04 8,709E-03 GO:0060538|skeletal muscle organ development, ! skeletal muscle fiber development GO:0048741 130 56 3,000 3,298E-04 9,052E-03 ! regulation of DNA replication GO:0006275 105 56 3,000 3,298E-04 8,951E-03 ! neuron fate determination GO:0048664 7 5 1,000 3,369E-04 9,044E-03 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 1,000 3,369E-04 8,946E-03 ! positive regulation of glycolysis GO:0045821 13 5 1,000 3,369E-04 8,849E-03 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 1,000 3,369E-04 8,755E-03 ! negative regulation of survival gene product expression GO:0008634 9 5 1,000 3,369E-04 8,663E-03 ! microvillus organization GO:0032528 8 5 1,000 3,369E-04 8,573E-03 GO:0030033|microvillus assembly, ! morphogenesis of an epithelial sheet GO:0002011 11 5 1,000 3,369E-04 8,484E-03 ! regulation of phospholipase A2 activity GO:0032429 15 5 1,000 3,369E-04 8,398E-03 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 1,000 3,369E-04 8,313E-03 ! inner cell mass cell proliferation GO:0001833 5 5 1,000 3,369E-04 8,23E-03 ! protein insertion into membrane GO:0051205 17 5 1,000 3,369E-04 8,148E-03 ! stem cell division GO:0017145 11 5 1,000 3,369E-04 8,069E-03 GO:0048103|somatic stem cell division, ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 3,000 3,53E-04 8,373E-03 ! muscle fiber development GO:0048747 131 57 3,000 3,53E-04 8,293E-03 ! regulation of intracellular transport GO:0032386 108 57 3,000 3,53E-04 8,214E-03 ! sex determination GO:0007530 48 24 2,000 3,651E-04 8,415E-03 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 2,000 3,651E-04 8,336E-03 ! positive regulation of cell migration GO:0030335 137 58 3,000 3,775E-04 8,538E-03 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 2,000 4,131E-04 9,259E-03 ! vasculogenesis GO:0001570 49 25 2,000 4,131E-04 9,175E-03 ! regulation of insulin secretion GO:0050796 42 25 2,000 4,131E-04 9,092E-03 ! regulation of transcription factor import into nucleus GO:0042990 58 26 2,000 4,65E-04 0,01014241 ! negative regulation of cell development GO:0010721 83 26 2,000 4,65E-04 0,01005265 GO:0050768|negative regulation of neurogenesis, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 1,000 5,034E-04 0,01078704 ! vascular smooth muscle contraction GO:0014829 13 6 1,000 5,034E-04 0,01069324 ! positive regulation of neuroblast proliferation GO:0002052 13 6 1,000 5,034E-04 0,01060106 ! early endosome to late endosome transport GO:0045022 16 6 1,000 5,034E-04 0,01051045 ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 1,000 5,034E-04 0,01042138 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! negative regulation of gliogenesis GO:0014014 18 6 1,000 5,034E-04 0,01033381 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 1,000 5,034E-04 0,01024769 ! response to UV-C GO:0010225 14 6 1,000 5,034E-04 0,010163 ! negative regulation of neuroblast proliferation GO:0007406 25 6 1,000 5,034E-04 0,0100797 ! progesterone metabolic process GO:0042448 12 6 1,000 5,034E-04 9,998E-03 ! triglyceride catabolic process GO:0019433 10 6 1,000 5,034E-04 9,917E-03 ! skeletal system morphogenesis GO:0048705 118 63 3,000 5,18E-04 0,01012365 ! protein amino acid autophosphorylation GO:0046777 157 64 3,000 5,5E-04 0,01066417 ! response to peptide hormone stimulus GO:0043434 129 64 3,000 5,5E-04 0,0105802 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 2,000 5,809E-04 0,01108608 ! fat cell differentiation GO:0045444 57 28 2,000 5,809E-04 0,01100014 ! positive regulation of cell motion GO:0051272 157 65 3,000 5,834E-04 0,01096377 ! ear development GO:0043583 114 66 3,000 6,182E-04 0,01152941 ! regulation of peptide secretion GO:0002791 52 29 2,000 6,451E-04 0,01193902 ! cytokinesis during cell cycle GO:0033205 14 7 1,000 7,02E-04 0,01289453 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 7,02E-04 0,0127983 ! N-terminal protein amino acid acetylation GO:0006474 14 7 1,000 7,02E-04 0,0127035 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 1,000 7,02E-04 0,01261009 ! neuron remodeling GO:0016322 16 7 1,000 7,02E-04 0,01251805 ! regulation of odontogenesis GO:0042481 14 7 1,000 7,02E-04 0,01242734 ! positive regulation of heart rate GO:0010460 11 7 1,000 7,02E-04 0,01233793 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 1,000 7,02E-04 0,0122498 ! microtubule nucleation GO:0007020 21 7 1,000 7,02E-04 0,01216292 ! phasic smooth muscle contraction GO:0014821 12 7 1,000 7,02E-04 0,01207727 ! glycerol ether catabolic process GO:0044269 12 7 1,000 7,02E-04 0,01199281 GO:0046464|acylglycerol catabolic process, ! male sex determination GO:0030238 15 7 1,000 7,02E-04 0,01190953 ! positive regulation of mitotic cell cycle GO:0045931 14 7 1,000 7,02E-04 0,0118274 ! centrosome duplication GO:0051298 14 7 1,000 7,02E-04 0,01174639 ! cranial nerve morphogenesis GO:0021602 12 7 1,000 7,02E-04 0,01166648 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 1,000 7,02E-04 0,01158765 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 2,000 7,137E-04 0,01170157 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 3,000 7,315E-04 0,01191395 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 3,000 7,315E-04 0,01183505 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 3,000 8,587E-04 0,01380186 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 3,000 8,587E-04 0,01371165 ! regulation of protein import into nucleus GO:0042306 69 32 2,000 8,644E-04 0,01371285 ! positive regulation of catabolic process GO:0009896 72 32 2,000 8,644E-04 0,01362438 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 1,000 9,324E-04 0,01460138 ! generation of neurons in the forebrain GO:0021872 18 8 1,000 9,324E-04 0,01450837 ! macrophage chemotaxis GO:0048246 12 8 1,000 9,324E-04 0,01441655 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 1,000 9,324E-04 0,01432588 ! glycerolipid catabolic process GO:0046503 14 8 1,000 9,324E-04 0,01423634 ! inositol phosphate-mediated signaling GO:0048016 11 8 1,000 9,324E-04 0,01414792 ! macrophage activation GO:0042116 13 8 1,000 9,324E-04 0,01406059 ! cerebral cortex neuron differentiation GO:0021895 16 8 1,000 9,324E-04 0,01397432 ! regulation of T cell differentiation in the thymus GO:0033081 14 8 1,000 9,324E-04 0,01388911 ! regulation of respiratory burst GO:0060263 12 8 1,000 9,324E-04 0,01380494 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 1,000 9,324E-04 0,01372178 GO:0002688|regulation of leukocyte chemotaxis, ! blastocyst growth GO:0001832 19 8 1,000 9,324E-04 0,01363961 ! positive regulation of smooth muscle contraction GO:0045987 15 8 1,000 9,324E-04 0,01355842 ! negative regulation of protein transport GO:0051224 74 33 2,000 9,468E-04 0,01368632 ! positive regulation of ligase activity GO:0051351 130 77 3,000 1,104E-03 0,01586795 ! regulation of catabolic process GO:0009894 173 77 3,000 1,104E-03 0,01577516 ! calcium-mediated signaling GO:0019722 67 35 2,000 1,126E-03 0,01599358 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 1,194E-03 0,01686321 ! neutral lipid catabolic process GO:0046461 14 9 1,000 1,194E-03 0,01676629 ! regulation of glycolysis GO:0006110 20 9 1,000 1,194E-03 0,01667048 ! middle ear morphogenesis GO:0042474 14 9 1,000 1,194E-03 0,01657576 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 1,000 1,194E-03 0,01648212 ! receptor clustering GO:0043113 20 9 1,000 1,194E-03 0,01638952 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 1,000 1,194E-03 0,01629796 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 1,000 1,194E-03 0,01620741 ! regulation of cell division GO:0051302 17 9 1,000 1,194E-03 0,01611787 ! regulation of telomere maintenance GO:0032204 17 9 1,000 1,194E-03 0,01602931 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 3,000 1,215E-03 0,01621816 ! androgen receptor signaling pathway GO:0030521 81 37 2,000 1,325E-03 0,01759687 ! meiosis GO:0007126 143 81 3,000 1,333E-03 0,01760384 GO:0051327|M phase of meiotic cell cycle, ! positive regulation of phosphorylation GO:0042327 149 81 3,000 1,333E-03 0,0175092 ! meiotic cell cycle GO:0051321 144 82 3,000 1,395E-03 0,01822574 ! embryonic skeletal system morphogenesis GO:0048704 68 38 2,000 1,433E-03 0,01861854 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 3,000 1,459E-03 0,01886014 GO:0045937|positive regulation of phosphate metabolic process, ! regulation of developmental growth GO:0048638 16 10 1,000 1,487E-03 0,01911907 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 1,000 1,487E-03 0,01901897 ! positive regulation of B cell proliferation GO:0030890 18 10 1,000 1,487E-03 0,01891991 ! cell volume homeostasis GO:0006884 17 10 1,000 1,487E-03 0,01882188 ! positive regulation of heart contraction GO:0045823 17 10 1,000 1,487E-03 0,01872486 ! negative regulation of striated muscle development GO:0045843 26 10 1,000 1,487E-03 0,01862884 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 1,000 1,487E-03 0,01853379 ! multicellular organism growth GO:0035264 19 10 1,000 1,487E-03 0,01843971 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 1,000 1,487E-03 0,01834658 ! motor axon guidance GO:0008045 22 10 1,000 1,487E-03 0,01825439 ! protein heterooligomerization GO:0051291 17 10 1,000 1,487E-03 0,01816312 ! regulation of gliogenesis GO:0014013 23 10 1,000 1,487E-03 0,01807275 GO:0045685|regulation of glial cell differentiation, ! blastoderm segmentation GO:0007350 19 10 1,000 1,487E-03 0,01798328 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 1,000 1,487E-03 0,0178947 GO:0043470|regulation of carbohydrate catabolic process, ! regulation of ligase activity GO:0051340 147 84 3,000 1,525E-03 0,01826396 ! cellular response to hormone stimulus GO:0032870 182 85 3,000 1,593E-03 0,01898605 ! regulation of protein transport GO:0051223 165 87 3,000 1,736E-03 0,02058294 GO:0070201|regulation of establishment of protein localization, ! regulation of hormone secretion GO:0046883 69 41 2,000 1,787E-03 0,02109409 ! mesenchymal cell development GO:0014031 94 41 2,000 1,787E-03 0,02099268 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! negative regulation of muscle development GO:0048635 27 11 1,000 1,81E-03 0,02116163 ! cortical actin cytoskeleton organization GO:0030866 29 11 1,000 1,81E-03 0,02106086 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 1,000 1,81E-03 0,02096105 ! detection of mechanical stimulus GO:0050982 22 11 1,000 1,81E-03 0,02086218 ! peptide or protein amino-terminal blocking GO:0018409 22 11 1,000 1,81E-03 0,02076423 ! positive regulation of muscle contraction GO:0045933 19 11 1,000 1,81E-03 0,0206672 ! vasoconstriction GO:0042310 20 11 1,000 1,81E-03 0,02057108 ! embryonic axis specification GO:0000578 19 11 1,000 1,81E-03 0,02047584 ! positive regulation of leukocyte migration GO:0002687 28 11 1,000 1,81E-03 0,02038148 ! thymus development GO:0048538 29 11 1,000 1,81E-03 0,02028799 ! oocyte development GO:0048599 20 11 1,000 1,81E-03 0,02019535 ! regulation of embryonic development GO:0045995 35 11 1,000 1,81E-03 0,02010355 ! ear morphogenesis GO:0042471 64 42 2,000 1,917E-03 0,02118655 ! dorsal/ventral pattern formation GO:0009953 75 42 2,000 1,917E-03 0,02109112 ! ossification GO:0001503 205 91 3,000 2,047E-03 0,02241998 ! segmentation GO:0035282 78 43 2,000 2,052E-03 0,02237434 ! bone development GO:0060348 206 92 3,000 2,13E-03 0,0231257 ! positive regulation of cellular catabolic process GO:0031331 34 12 1,000 2,164E-03 0,02339343 ! cortical cytoskeleton organization GO:0030865 30 12 1,000 2,164E-03 0,02329038 ! virus-host interaction GO:0019048 30 12 1,000 2,164E-03 0,02318823 ! regulation of B cell proliferation GO:0030888 22 12 1,000 2,164E-03 0,02308697 ! dopamine receptor signaling pathway GO:0007212 28 12 1,000 2,164E-03 0,02298659 ! hippocampus development GO:0021766 29 12 1,000 2,164E-03 0,02288708 ! focal adhesion formation GO:0048041 37 12 1,000 2,164E-03 0,02278843 ! cranial nerve development GO:0021545 23 12 1,000 2,164E-03 0,02269063 ! histone acetylation GO:0016573 27 12 1,000 2,164E-03 0,02259366 ! autonomic nervous system development GO:0048483 24 12 1,000 2,164E-03 0,02249752 ! peptidyl-lysine modification GO:0018205 21 12 1,000 2,164E-03 0,02240219 ! T cell homeostasis GO:0043029 28 12 1,000 2,164E-03 0,02230766 ! regulation of leukocyte migration GO:0002685 29 12 1,000 2,164E-03 0,02221393 ! oocyte differentiation GO:0009994 21 12 1,000 2,164E-03 0,02212099 ! negative regulation of mast cell proliferation GO:0070667 24 12 1,000 2,164E-03 0,02202882 GO:0042130|negative regulation of T cell proliferation, ! localization within membrane GO:0051668 26 12 1,000 2,164E-03 0,02193741 ! positive regulation of MAP kinase activity GO:0043406 174 93 3,000 2,216E-03 0,02236596 ! maintenance of location in cell GO:0051651 101 45 2,000 2,339E-03 0,02351258 ! regulation of defense response GO:0031347 171 95 3,000 2,394E-03 0,02396883 ! positive regulation of protein transport GO:0051222 80 46 2,000 2,491E-03 0,02484098 ! double-strand break repair via homologous recombination GO:0000724 19 13 1,000 2,548E-03 0,0253014 GO:0000725|recombinational repair, ! response to X-ray GO:0010165 28 13 1,000 2,548E-03 0,02519896 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 1,000 2,548E-03 0,02509735 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 35 13 1,000 2,548E-03 0,02499656 ! regulation of monooxygenase activity GO:0032768 35 13 1,000 2,548E-03 0,02489657 ! spleen development GO:0048536 24 13 1,000 2,548E-03 0,02479738 ! anterior/posterior axis specification GO:0009948 22 13 1,000 2,548E-03 0,02469898 ! cytoplasmic sequestering of protein GO:0051220 25 13 1,000 2,548E-03 0,02460136 ! regulation of protein localization GO:0032880 188 97 3,000 2,582E-03 0,02483378 ! regulation of S phase GO:0033261 26 14 1,000 2,961E-03 0,028367 ! regulation of heart rate GO:0002027 25 14 1,000 2,961E-03 0,0282562 ! bone mineralization GO:0030282 18 14 1,000 2,961E-03 0,02814625 ! response to gamma radiation GO:0010332 30 14 1,000 2,961E-03 0,02803716 ! release of cytochrome c from mitochondria GO:0001836 31 14 1,000 2,961E-03 0,0279289 ! regulation of mast cell proliferation GO:0070666 89 49 2,000 2,985E-03 0,02804744 ! induction of apoptosis by extracellular signals GO:0008624 99 50 2,000 3,162E-03 0,02959642 ! N-terminal protein amino acid modification GO:0031365 30 15 1,000 3,403E-03 0,03173426 ! regulation of mRNA processing GO:0050684 26 15 1,000 3,403E-03 0,03161359 ! actin cytoskeleton reorganization GO:0031532 38 15 1,000 3,403E-03 0,03149385 ! G1/S transition checkpoint GO:0031575 37 15 1,000 3,403E-03 0,031375 ! cAMP biosynthetic process GO:0006171 25 15 1,000 3,403E-03 0,03125705 ! lymphocyte homeostasis GO:0002260 33 15 1,000 3,403E-03 0,03113998 ! inner ear development GO:0048839 89 53 2,000 3,731E-03 0,03401051 ! regulation of leukocyte proliferation GO:0070663 97 53 2,000 3,731E-03 0,03388407 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of glucose metabolic process GO:0010906 28 16 1,000 3,875E-03 0,03505796 ! biomineral formation GO:0031214 22 16 1,000 3,875E-03 0,0349286 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 1,000 3,875E-03 0,03480018 ! negative regulation of leukocyte proliferation GO:0070664 32 16 1,000 3,875E-03 0,03467271 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 1,000 3,875E-03 0,03454617 ! pituitary gland development GO:0021983 30 16 1,000 3,875E-03 0,03442054 ! neuron recognition GO:0008038 40 16 1,000 3,875E-03 0,03429583 ! regulation of protein catabolic process GO:0042176 126 56 2,000 4,359E-03 0,03844095 ! embryonic forelimb morphogenesis GO:0035115 31 17 1,000 4,374E-03 0,03844085 ! signal complex assembly GO:0007172 47 17 1,000 4,374E-03 0,03830307 ! auditory receptor cell differentiation GO:0042491 36 17 1,000 4,374E-03 0,03816627 ! regulation of survival gene product expression GO:0045884 38 17 1,000 4,374E-03 0,03803045 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 1,000 4,374E-03 0,03789559 ! maintenance of location GO:0051235 124 58 2,000 4,81E-03 0,04152635 ! limbic system development GO:0021761 40 18 1,000 4,902E-03 0,04216988 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 1,000 4,902E-03 0,04202192 GO:0050886|endocrine process, ! centrosome cycle GO:0007098 26 18 1,000 4,902E-03 0,04187499 ! cell-substrate junction assembly GO:0007044 56 18 1,000 4,902E-03 0,04172908 ! negative regulation of protein catabolic process GO:0042177 42 18 1,000 4,902E-03 0,04158419 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 1,000 4,902E-03 0,0414403 ! nerve development GO:0021675 34 18 1,000 4,902E-03 0,0412974 ! lipid modification GO:0030258 112 60 2,000 5,29E-03 0,04440682 ! neuron maturation GO:0042551 46 19 1,000 5,458E-03 0,04566398 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 1,000 5,458E-03 0,04550813 ! neuromuscular junction development GO:0007528 43 19 1,000 5,458E-03 0,04535334 ! positive regulation of secretion GO:0051047 110 61 2,000 5,539E-03 0,04587429 ! negative regulation of response to stimulus GO:0048585 106 61 2,000 5,539E-03 0,04571931 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 1,000 6,041E-03 0,04969237 ! positive regulation of ossification GO:0045778 50 20 1,000 6,041E-03 0,04952561 ! protein amino acid acetylation GO:0006473 41 20 1,000 6,041E-03 0,04935998 ! regulation of carbohydrate metabolic process GO:0006109 37 20 1,000 6,041E-03 0,04919544 GO:0010675|regulation of cellular carbohydrate metabolic process, ! forelimb morphogenesis GO:0035136 35 20 1,000 6,041E-03 0,049032 ! response to alkaloid GO:0043279 38 20 1,000 6,041E-03 0,04886965 ! apoptotic mitochondrial changes GO:0008637 42 20 1,000 6,041E-03 0,04870836 ! actin filament bundle formation GO:0051017 47 20 1,000 6,041E-03 0,04854814 ! negative regulation of T cell activation GO:0050868 41 20 1,000 6,041E-03 0,04838896 ! phosphatidylinositol metabolic process GO:0046488 47 21 1,000 6,652E-03 0,05310351 ! cAMP metabolic process GO:0046058 41 21 1,000 6,652E-03 0,05293053 ! C21-steroid hormone metabolic process GO:0008207 38 21 1,000 6,652E-03 0,05275868 ! smooth muscle contraction GO:0006939 48 21 1,000 6,652E-03 0,05258794 ! cell structure disassembly during apoptosis GO:0006921 32 21 1,000 6,652E-03 0,0524183 ! diencephalon development GO:0021536 36 21 1,000 6,652E-03 0,05224976 ! negative regulation of intracellular transport GO:0032387 44 21 1,000 6,652E-03 0,05208229 ! positive regulation of osteoblast differentiation GO:0045669 52 21 1,000 6,652E-03 0,05191589 ! gonad development GO:0008406 115 66 2,000 6,895E-03 0,0536424 ! steroid hormone receptor signaling pathway GO:0030518 146 66 2,000 6,895E-03 0,0534721 ! positive regulation of protein catabolic process GO:0045732 44 22 1,000 7,289E-03 0,0563487 ! positive regulation of bone remodeling GO:0046852 54 22 1,000 7,289E-03 0,05617094 GO:0034105|positive regulation of tissue remodeling, ! hindlimb morphogenesis GO:0035137 47 22 1,000 7,289E-03 0,0559943 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 1,000 7,289E-03 0,05581877 ! central nervous system neuron development GO:0021954 47 22 1,000 7,289E-03 0,05564434 ! apoptotic nuclear changes GO:0030262 34 22 1,000 7,289E-03 0,05547099 ! cell aging GO:0007569 48 22 1,000 7,289E-03 0,05529872 ! stem cell differentiation GO:0048863 57 22 1,000 7,289E-03 0,05512752 ! response to glucocorticoid stimulus GO:0051384 42 22 1,000 7,289E-03 0,05495737 ! positive regulation of B cell activation GO:0050871 42 22 1,000 7,289E-03 0,05478827 ! inner ear receptor cell differentiation GO:0060113 42 22 1,000 7,289E-03 0,05462021 ! protein stabilization GO:0050821 41 22 1,000 7,289E-03 0,05445317 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 2,000 7,487E-03 0,05576415 ! lung development GO:0030324 165 69 2,000 7,794E-03 0,05787478 ! positive regulation of DNA replication GO:0045740 44 23 1,000 7,952E-03 0,0588708 ! gluconeogenesis GO:0006094 38 23 1,000 7,952E-03 0,05869295 ! axis specification GO:0009798 43 23 1,000 7,952E-03 0,05851616 ! activation of pro-apoptotic gene products GO:0008633 51 23 1,000 7,952E-03 0,05834044 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 1,000 7,952E-03 0,05816576 ! germ cell development GO:0007281 133 70 2,000 8,108E-03 0,05913102 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 2,000 8,43E-03 0,06129465 ! positive regulation of cell adhesion GO:0045785 61 24 1,000 8,642E-03 0,06264808 ! regulation of cellular catabolic process GO:0031329 55 24 1,000 8,642E-03 0,06246273 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 1,000 8,642E-03 0,06227847 ! mechanoreceptor differentiation GO:0042490 48 24 1,000 8,642E-03 0,0620953 ! central nervous system neuron differentiation GO:0021953 51 24 1,000 8,642E-03 0,06191321 ! response to corticosteroid stimulus GO:0031960 46 24 1,000 8,642E-03 0,06173217 ! pallium development GO:0021543 56 24 1,000 8,642E-03 0,0615522 ! oogenesis GO:0048477 44 24 1,000 8,642E-03 0,06137326 ! regulation of oxidoreductase activity GO:0051341 48 24 1,000 8,642E-03 0,06119537 ! negative regulation of catabolic process GO:0009895 52 24 1,000 8,642E-03 0,06101851 ! respiratory tube development GO:0030323 171 72 2,000 8,759E-03 0,06166924 ! positive regulation of fibroblast proliferation GO:0048146 48 25 1,000 9,358E-03 0,06569111 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 1,000 9,358E-03 0,06550288 ! negative regulation of DNA replication GO:0008156 45 25 1,000 9,358E-03 0,06531573 ! receptor metabolic process GO:0043112 53 25 1,000 9,358E-03 0,06512965 ! interaction with host GO:0051701 66 25 1,000 9,358E-03 0,06494462 ! leukocyte homeostasis GO:0001776 50 25 1,000 9,358E-03 0,06476064 ! liver development GO:0001889 55 25 1,000 9,358E-03 0,0645777 ! protein tetramerization GO:0051262 57 25 1,000 9,358E-03 0,06439579 ! regulation of caspase activity GO:0043281 136 74 2,000 9,44E-03 0,06478187 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 2,000 9,44E-03 0,0646004 ! respiratory system development GO:0060541 175 74 2,000 9,44E-03 0,06441996 ! reproductive structure development GO:0048608 131 75 2,000 9,792E-03 0,06663343 ! axon guidance GO:0007411 162 75 2,000 9,792E-03 0,06644834 ! myelination GO:0042552 50 26 1,000 0,0100986 0,0683404 ! pyruvate metabolic process GO:0006090 43 26 1,000 0,0100986 0,06815162 ! microtubule organizing center organization GO:0031023 42 26 1,000 0,0100986 0,06796387 GO:0051297|centrosome organization, ! regulation of smooth muscle contraction GO:0006940 48 26 1,000 0,0100986 0,06777716 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 1,000 0,0100986 0,06759147 ! osteoblast differentiation GO:0001649 63 26 1,000 0,0100986 0,06740679 ! regulation of osteoblast differentiation GO:0045667 68 26 1,000 0,0100986 0,06722312 ! blastocyst development GO:0001824 50 26 1,000 0,0100986 0,06704045 ! neural tube closure GO:0001843 58 26 1,000 0,0100986 0,06685877 GO:0060606|tube closure, ! learning or memory GO:0007611 161 76 2,000 0,010151 0,06702404 ! phosphoinositide metabolic process GO:0030384 146 77 2,000 0,01051776 0,06925848 ! regulation of endopeptidase activity GO:0052548 141 77 2,000 0,01051776 0,0690723 ! embryonic pattern specification GO:0009880 49 27 1,000 0,01086482 0,07116022 ! tube lumen formation GO:0035148 59 27 1,000 0,01086482 0,07096995 ! regulation of chromosome organization GO:0033044 49 27 1,000 0,01086482 0,07078069 ! negative regulation of lymphocyte activation GO:0051250 55 27 1,000 0,01086482 0,07059245 ! response to steroid hormone stimulus GO:0048545 147 79 2,000 0,01127413 0,07305754 ! protein oligomerization GO:0051259 149 79 2,000 0,01127413 0,07286427 ! regulation of fibroblast proliferation GO:0048145 56 28 1,000 0,0116559 0,07513287 ! neuron fate commitment GO:0048663 52 28 1,000 0,0116559 0,07493515 ! spliceosomal snRNP biogenesis GO:0000387 40 28 1,000 0,0116559 0,07473847 ! protein amino acid acylation GO:0043543 59 28 1,000 0,0116559 0,07454282 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 1,000 0,0116559 0,07434819 ! regulation of systemic arterial blood pressure GO:0003073 55 28 1,000 0,0116559 0,07415457 ! peptidyl-tyrosine modification GO:0018212 57 28 1,000 0,0116559 0,07396196 ! glutathione metabolic process GO:0006749 42 28 1,000 0,0116559 0,07377035 ! activation of protein kinase activity GO:0032147 170 80 2,000 0,01166378 0,0736295 ! development of primary sexual characteristics GO:0045137 143 80 2,000 0,01166378 0,07343973 ! muscle cell differentiation GO:0042692 178 81 2,000 0,01206112 0,07574629 ! regulation of peptidase activity GO:0052547 150 82 2,000 0,01246615 0,07808927 ! cellular iron ion homeostasis GO:0006879 57 29 1,000 0,01247151 0,07792303 ! autophagy GO:0006914 47 29 1,000 0,01247151 0,07772425 ! primary neural tube formation GO:0014020 61 29 1,000 0,01247151 0,07752648 ! response to organic cyclic substance GO:0014070 58 29 1,000 0,01247151 0,07732971 ! somitogenesis GO:0001756 52 29 1,000 0,01247151 0,07713394 ! response to drug GO:0042493 149 83 2,000 0,01287892 0,07945252 ! cell fate determination GO:0001709 64 30 1,000 0,01331136 0,08191346 ! tissue homeostasis GO:0001894 50 30 1,000 0,01331136 0,08170765 GO:0048871|multicellular organismal homeostasis, ! regulation of B cell activation GO:0050864 55 30 1,000 0,01331136 0,08150287 ! male gonad development GO:0008584 56 31 1,000 0,01417512 0,08657456 ! iron ion homeostasis GO:0055072 60 31 1,000 0,01417512 0,08635866 ! cellular response to extracellular stimulus GO:0031668 52 31 1,000 0,01417512 0,08614384 ! ensheathment of neurons GO:0007272 64 31 1,000 0,01417512 0,08593009 GO:0008366|axon ensheathment, ! negative regulation of leukocyte activation GO:0002695 60 31 1,000 0,01417512 0,08571739 ! spindle organization GO:0007051 50 32 1,000 0,0150625 0,0908585 ! metanephros development GO:0001656 81 32 1,000 0,0150625 0,09063471 ! response to mechanical stimulus GO:0009612 60 32 1,000 0,0150625 0,09041202 ! hexose biosynthetic process GO:0019319 53 32 1,000 0,0150625 0,09019043 ! peripheral nervous system development GO:0007422 68 32 1,000 0,0150625 0,08996991 ! hindbrain development GO:0030902 65 32 1,000 0,0150625 0,08975047 ! myeloid leukocyte activation GO:0002274 53 32 1,000 0,0150625 0,0895321 ! cholesterol homeostasis GO:0042632 60 33 1,000 0,01597319 0,09471484 GO:0055092|sterol homeostasis, ! triglyceride metabolic process GO:0006641 46 33 1,000 0,01597319 0,09448551 ! response to ionizing radiation GO:0010212 74 33 1,000 0,01597319 0,09425728 ! positive regulation of neurogenesis GO:0050769 72 33 1,000 0,01597319 0,09403015 ! positive regulation of protein modification process GO:0031401 156 90 2,000 0,01598618 0,09388039 ! regulation of cell cycle process GO:0010564 161 90 2,000 0,01598618 0,09365526 ! inner ear morphogenesis GO:0042472 51 34 1,000 0,0169069 0,09881232 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 1,000 0,0169069 0,09857649 ! regulation of cell adhesion GO:0030155 241 92 2,000 0,01694448 0,09856041 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 2,000 0,01743545 0,1011753 GO:0010498|proteasomal protein catabolic process, ! negative regulation of DNA metabolic process GO:0051053 65 35 1,000 0,01786331 0,1034125 ! regulation of striated muscle tissue development GO:0016202 81 35 1,000 0,01786331 0,10316802 ! mesoderm morphogenesis GO:0048332 80 35 1,000 0,01786331 0,1029247 ! telencephalon development GO:0021537 81 35 1,000 0,01786331 0,10268253 ! regulation of muscle development GO:0048634 82 36 1,000 0,01884215 0,10805485 ! positive regulation of cell development GO:0010720 85 36 1,000 0,01884215 0,10780179 ! cytokine production GO:0001816 68 36 1,000 0,01884215 0,10754992 ! monosaccharide biosynthetic process GO:0046364 57 36 1,000 0,01884215 0,10729922 ! sex differentiation GO:0007548 171 96 2,000 0,01895571 0,10769487 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 1,000 0,01984311 0,11247497 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! negative regulation of cell adhesion GO:0007162 94 37 1,000 0,01984311 0,11221461 ! maintenance of protein location in cell GO:0032507 89 37 1,000 0,01984311 0,11195545 ! female gonad development GO:0008585 71 37 1,000 0,01984311 0,11169749 ! hormone biosynthetic process GO:0042446 62 37 1,000 0,01984311 0,11144072 ! negative regulation of cell activation GO:0050866 69 37 1,000 0,01984311 0,11118512 ! positive regulation of DNA metabolic process GO:0051054 77 38 1,000 0,0208659 0,11664852 ! meiosis I GO:0007127 74 38 1,000 0,0208659 0,1163822 ! neutral lipid metabolic process GO:0006638 54 38 1,000 0,0208659 0,11611709 GO:0006639|acylglycerol metabolic process, ! cyclic nucleotide metabolic process GO:0009187 69 38 1,000 0,0208659 0,11585319 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 1,000 0,0208659 0,11559048 ! regulation of protein stability GO:0031647 77 38 1,000 0,0208659 0,11532896 ! neural tube formation GO:0001841 79 38 1,000 0,0208659 0,11506863 ! mitotic cell cycle checkpoint GO:0007093 76 39 1,000 0,02191025 0,12055571 ! positive regulation of leukocyte proliferation GO:0070665 70 39 1,000 0,02191025 0,1202848 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! learning GO:0007612 82 40 1,000 0,02297586 0,12585206 ! development of primary female sexual characteristics GO:0046545 80 40 1,000 0,02297586 0,12557051 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 73 40 1,000 0,02297586 0,12529022 ! lipid homeostasis GO:0055088 75 40 1,000 0,02297586 0,12501117 ! regulation of action potential in neuron GO:0019228 80 40 1,000 0,02297586 0,12473337 ! glycerol ether metabolic process GO:0006662 57 40 1,000 0,02297586 0,1244568 ! phosphoinositide biosynthetic process GO:0046489 77 41 1,000 0,02406245 0,13005433 ! maintenance of protein location GO:0045185 95 41 1,000 0,02406245 0,12976724 ! embryonic epithelial tube formation GO:0001838 85 41 1,000 0,02406245 0,1294814 ! organic ether metabolic process GO:0018904 59 42 1,000 0,02516974 0,13514214 ! alcohol biosynthetic process GO:0046165 65 42 1,000 0,02516974 0,13484578 ! T cell differentiation GO:0030217 93 42 1,000 0,02516974 0,13455071 ! regulation of T cell differentiation GO:0045580 78 42 1,000 0,02516974 0,13425693 ! cytokinesis GO:0000910 84 42 1,000 0,02516974 0,13396443 ! positive regulation of transcription factor activity GO:0051091 71 43 1,000 0,02629746 0,13966237 GO:0090047|positive regulation of transcription regulator activity, ! regulation of tube size GO:0035150 76 43 1,000 0,02629746 0,13935941 GO:0050880|regulation of blood vessel size, ! glucose transport GO:0015758 66 43 1,000 0,02629746 0,13905777 ! development of primary male sexual characteristics GO:0046546 80 43 1,000 0,02629746 0,13875743 ! regulation of T cell proliferation GO:0042129 80 43 1,000 0,02629746 0,13845838 ! neuron migration GO:0001764 85 43 1,000 0,02629746 0,13816062 ! hexose transport GO:0008645 68 44 1,000 0,02744533 0,14388183 GO:0015749|monosaccharide transport, ! double-strand break repair GO:0006302 85 44 1,000 0,02744533 0,14357373 ! receptor-mediated endocytosis GO:0006898 98 45 1,000 0,02861308 0,1493627 ! female gamete generation GO:0007292 71 45 1,000 0,02861308 0,14904423 ! developmental growth GO:0048589 88 45 1,000 0,02861308 0,14872711 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 0,02892067 0,15000678 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 0,02892067 0,14968897 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 0,02892067 0,1493725 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,02892067 0,14905737 ! positive regulation of helicase activity GO:0051096 12 5 0,000 0,02892067 0,14874356 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02892067 0,14843108 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 0,02892067 0,1481199 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 0,02892067 0,14781003 ! polyol transport GO:0015791 12 5 0,000 0,02892067 0,14750145 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,02892067 0,14719415 ! response to superoxide GO:0000303 10 5 0,000 0,02892067 0,14688813 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,02892067 0,14658339 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 0,02892067 0,1462799 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 0,02892067 0,14597767 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,02892067 0,14567669 ! female meiosis GO:0007143 10 5 0,000 0,02892067 0,14537694 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 0,02892067 0,14507842 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,02892067 0,14478113 ! hypothalamus development GO:0021854 9 5 0,000 0,02892067 0,14448506 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 0,02892067 0,14419019 ! cobalt ion transport GO:0006824 11 5 0,000 0,02892067 0,14389652 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 0,02892067 0,14360405 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 0,02892067 0,14331276 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,02892067 0,14302266 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,02892067 0,14273372 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 0,02892067 0,14244595 ! embryonic camera-type eye development GO:0031076 12 5 0,000 0,02892067 0,14215934 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,02892067 0,14187388 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02892067 0,14158956 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 0,02892067 0,14130638 ! transposition GO:0032196 9 5 0,000 0,02892067 0,14102434 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 0,02892067 0,14074341 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 0,000 0,02892067 0,1404636 ! negative chemotaxis GO:0050919 16 5 0,000 0,02892067 0,14018491 ! positive regulation of histone modification GO:0031058 6 5 0,000 0,02892067 0,13990731 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,02892067 0,13963082 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 0,02892067 0,13935541 ! behavioral response to pain GO:0048266 10 5 0,000 0,02892067 0,13908109 ! clathrin coat assembly GO:0048268 15 5 0,000 0,02892067 0,13880784 ! Notch receptor processing GO:0007220 11 5 0,000 0,02892067 0,13853567 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02892067 0,13826456 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 0,02892067 0,13799452 ! micturition GO:0060073 9 5 0,000 0,02892067 0,13772552 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,02892067 0,13745757 ! copulation GO:0007620 9 5 0,000 0,02892067 0,13719066 ! glial cell fate commitment GO:0021781 14 5 0,000 0,02892067 0,13692479 ! protein maturation by protein folding GO:0022417 14 5 0,000 0,02892067 0,13665995 ! bioluminescence GO:0008218 9 5 0,000 0,02892067 0,13639612 ! spermidine metabolic process GO:0008216 7 5 0,000 0,02892067 0,13613332 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,02892067 0,13587152 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,02892067 0,13561073 ! apoptotic cell clearance GO:0043277 23 5 0,000 0,02892067 0,13535094 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,02892067 0,13509215 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 0,02892067 0,13483434 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,02892067 0,13457751 ! grooming behavior GO:0007625 6 5 0,000 0,02892067 0,13432166 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 0,02892067 0,13406678 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,02892067 0,13381286 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02892067 0,13355991 ! response to protozoan GO:0001562 13 5 0,000 0,02892067 0,13330791 ! lymph vessel development GO:0001945 10 5 0,000 0,02892067 0,13305686 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 0,02892067 0,13280675 ! endochondral ossification GO:0001958 17 5 0,000 0,02892067 0,13255758 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,02892067 0,13230935 ! single strand break repair GO:0000012 8 5 0,000 0,02892067 0,13206204 ! parathyroid gland development GO:0060017 14 5 0,000 0,02892067 0,13181566 ! anagen GO:0042640 7 5 0,000 0,02892067 0,13157019 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,02892067 0,13132564 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,02892067 0,13108199 ! cytokine secretion GO:0050663 15 5 0,000 0,02892067 0,13083925 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 0,02892067 0,1305974 ! ceramide catabolic process GO:0046514 7 5 0,000 0,02892067 0,13035644 ! skeletal myofibril assembly GO:0014866 12 5 0,000 0,02892067 0,13011638 ! smooth muscle tissue development GO:0048745 32 5 0,000 0,02892067 0,12987719 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,02892067 0,12963889 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,02892067 0,12940145 ! cardiac muscle fiber development GO:0048739 12 5 0,000 0,02892067 0,12916489 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,02892067 0,12892918 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,02892067 0,12869434 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 0,02892067 0,12846035 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,02892067 0,12822721 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 0,02892067 0,12799491 ! glycine biosynthetic process GO:0006545 7 5 0,000 0,02892067 0,12776346 ! valine metabolic process GO:0006573 12 5 0,000 0,02892067 0,12753284 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 0,02892067 0,12730305 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 0,02892067 0,12707409 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 0,02892067 0,12684595 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 0,02892067 0,12661862 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 0,02892067 0,12639212 ! polyol catabolic process GO:0046174 9 5 0,000 0,02892067 0,12616642 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 0,02892067 0,12594152 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 0,02892067 0,12571742 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 0,02892067 0,12549413 ! muscle cell migration GO:0014812 8 5 0,000 0,02892067 0,12527162 ! mitochondrial fission GO:0000266 8 5 0,000 0,02892067 0,1250499 ! sister chromatid cohesion GO:0007062 15 5 0,000 0,02892067 0,12482896 ! response to tumor necrosis factor GO:0034612 10 5 0,000 0,02892067 0,12460881 ! mRNA transcription GO:0009299 10 5 0,000 0,02892067 0,12438942 ! nerve growth factor processing GO:0032455 9 5 0,000 0,02892067 0,12417081 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 0,02892067 0,12395297 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 0,02892067 0,12373589 ! anaerobic glycolysis GO:0019642 6 5 0,000 0,02892067 0,12351957 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,02892067 0,123304 ! monocyte activation GO:0042117 10 5 0,000 0,02892067 0,12308919 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,02892067 0,12287512 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,02892067 0,12266179 ! response to food GO:0032094 6 5 0,000 0,02892067 0,12244921 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,02892067 0,12223736 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 0,02892067 0,12202624 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02892067 0,12181585 ! forebrain neuron development GO:0021884 13 5 0,000 0,02892067 0,12160618 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,02892067 0,12139724 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 0,02892067 0,12118901 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 0,02892067 0,12098149 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,02892067 0,12077469 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02892067 0,12056859 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 0,02892067 0,12036319 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,02892067 0,12015849 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 0,02892067 0,11995449 ! lipid glycosylation GO:0030259 7 5 0,000 0,02892067 0,11975117 ! nucleobase transport GO:0015851 6 5 0,000 0,02892067 0,11954855 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02892067 0,11934661 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 0,02892067 0,11914535 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 0,02892067 0,11894477 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 0,02892067 0,11874486 ! basic amino acid transport GO:0015802 12 5 0,000 0,02892067 0,11854562 ! cellular glucose homeostasis GO:0001678 6 5 0,000 0,02892067 0,11834706 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 0,02892067 0,11814915 ! actin nucleation GO:0045010 11 5 0,000 0,02892067 0,11795191 ! depurination GO:0045007 5 5 0,000 0,02892067 0,11775532 ! depyrimidination GO:0045008 10 5 0,000 0,02892067 0,11755939 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,02892067 0,11736411 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02892067 0,11716947 ! G2/M transition checkpoint GO:0031576 8 5 0,000 0,02892067 0,11697548 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,02892067 0,11678214 ! zinc ion homeostasis GO:0055069 9 5 0,000 0,02892067 0,11658943 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 10 5 0,000 0,02892067 0,11639735 ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 0,02892067 0,11620591 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02892067 0,11601509 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,02892067 0,11582491 ! activated T cell proliferation GO:0050798 16 5 0,000 0,02892067 0,11563534 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,02892067 0,11544639 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 0,02892067 0,11525806 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,02892067 0,11507035 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02892067 0,11488324 ! gamma-delta T cell activation GO:0046629 6 5 0,000 0,02892067 0,11469674 ! response to arsenic GO:0046685 11 5 0,000 0,02892067 0,11451085 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 0,02892067 0,11432555 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,02892067 0,11414086 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 0,02892067 0,11395676 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 0,02892067 0,11377326 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 0,02892067 0,11359034 ! response to mercury ion GO:0046689 8 5 0,000 0,02892067 0,11340801 ! response to cadmium ion GO:0046686 7 5 0,000 0,02892067 0,11322627 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 0,02892067 0,11304511 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 0,02892067 0,11286452 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 0,02892067 0,11268452 ! bile acid biosynthetic process GO:0006699 7 5 0,000 0,02892067 0,11250508 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 0,02892067 0,11232622 ! ganglioside catabolic process GO:0006689 12 5 0,000 0,02892067 0,11214792 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,02892067 0,11197019 ! decidualization GO:0046697 11 5 0,000 0,02892067 0,11179303 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 0,02892067 0,11161642 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 0,02892067 0,11144037 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 0,02892067 0,11126487 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 0,02892067 0,11108993 ! embryonic cleavage GO:0040016 6 5 0,000 0,02892067 0,11091553 ! peroxisome fission GO:0016559 5 5 0,000 0,02892067 0,11074168 ! histone demethylation GO:0016577 13 5 0,000 0,02892067 0,11056838 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 0,02892067 0,11039561 ! mitotic recombination GO:0006312 9 5 0,000 0,02892067 0,11022339 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 0,02892067 0,1100517 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,02892067 0,10988055 ! metaphase plate congression GO:0051310 7 5 0,000 0,02892067 0,10970993 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02892067 0,10953983 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,02892067 0,10937027 ! enteric nervous system development GO:0048484 8 5 0,000 0,02892067 0,10920122 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 0,02892067 0,1090327 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 0,02892067 0,1088647 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 0,02892067 0,10869722 ! muscle cell proliferation GO:0033002 12 5 0,000 0,02892067 0,10853025 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,02892067 0,10836379 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 0,02892067 0,10819784 ! B cell homeostasis GO:0001782 13 5 0,000 0,02892067 0,1080324 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 0,02892067 0,10786747 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,02892067 0,10770304 ! metaphase GO:0051323 11 5 0,000 0,02892067 0,10753911 ! melatonin biosynthetic process GO:0030187 7 5 0,000 0,02892067 0,10737567 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 0,02892067 0,10721274 ! cellular response to nutrient GO:0031670 8 5 0,000 0,02892067 0,10705029 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,02892067 0,10688834 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 0,02892067 0,10672688 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 0,02892067 0,1065659 ! regulation of hair follicle development GO:0051797 10 5 0,000 0,02892067 0,10640541 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 0,02892067 0,1062454 ! response to redox state GO:0051775 6 5 0,000 0,02892067 0,10608587 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 0,02892067 0,10592683 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 0,02892067 0,10576825 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,02892067 0,10561015 ! brown fat cell differentiation GO:0050873 7 5 0,000 0,02892067 0,10545253 ! regulation of telomerase activity GO:0051972 7 5 0,000 0,02892067 0,10529537 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02892067 0,10513868 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 0,02892067 0,10498246 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02892067 0,1048267 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 0,02892067 0,1046714 ! striatum development GO:0021756 14 5 0,000 0,02892067 0,10451656 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 0,02892067 0,10436217 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,02892067 0,10420825 ! glial cell migration GO:0008347 10 5 0,000 0,02892067 0,10405478 ! neural plate morphogenesis GO:0001839 7 5 0,000 0,02892067 0,10390175 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 0,02892067 0,10374918 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,02892067 0,10359706 ! T cell activation during immune response GO:0002286 9 5 0,000 0,02892067 0,10344538 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,02892067 0,10329414 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,02892067 0,10314335 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 0,02892067 0,10299299 ! neuroprotection GO:0043526 8 5 0,000 0,02892067 0,10284307 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,02892067 0,10269359 ! regulation of sensory perception GO:0051931 8 5 0,000 0,02892067 0,10254455 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,02892067 0,10239593 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,02892067 0,10224775 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 0,02892067 0,10209999 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 0,02892067 0,10195266 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,02892067 0,10180575 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 0,02892067 0,10165927 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,02892067 0,10151321 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 0,02892067 0,10136756 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 0,02892067 0,10122234 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,02892067 0,10107753 ! spindle assembly GO:0051225 6 5 0,000 0,02892067 0,10093313 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,02892067 0,10078915 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,02892067 0,10064557 ! protein palmitoylation GO:0018345 12 5 0,000 0,02892067 0,10050241 ! drug metabolic process GO:0017144 7 5 0,000 0,02892067 0,10035965 ! phospholipid scrambling GO:0017121 8 5 0,000 0,02892067 0,10021729 ! organ regeneration GO:0031100 7 5 0,000 0,02892067 0,10007534 ! carnitine metabolic process GO:0009437 8 5 0,000 0,02892067 0,09993379 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,02892067 0,09979264 ! regulation of gene-specific transcription GO:0032583 102 46 1,000 0,02980043 0,10268329 ! pigmentation GO:0043473 103 46 1,000 0,02980043 0,10253867 ! neural tube development GO:0021915 91 47 1,000 0,03100713 0,10654068 ! cellular component disassembly GO:0022411 89 48 1,000 0,03223291 0,1105969 ! endosome transport GO:0016197 127 48 1,000 0,03223291 0,11044179 ! positive regulation of DNA binding GO:0043388 83 48 1,000 0,03223291 0,11028711 ! vascular process in circulatory system GO:0003018 85 48 1,000 0,03223291 0,11013286 ! male sex differentiation GO:0046661 93 48 1,000 0,03223291 0,10997904 ! detection of stimulus involved in sensory perception GO:0050906 75 49 1,000 0,0334775 0,1140663 ! regulation of lymphocyte differentiation GO:0045619 92 49 1,000 0,0334775 0,11390743 ! protein homooligomerization GO:0051260 84 49 1,000 0,0334775 0,11374901 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,03460413 0,11741373 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,03460413 0,11725088 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 0,03460413 0,11708849 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 0,03460413 0,11692654 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,03460413 0,11676504 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 0,03460413 0,11660398 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 0,03460413 0,11644337 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,03460413 0,1162832 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 0,03460413 0,11612347 ! response to oxygen radical GO:0000305 11 6 0,000 0,03460413 0,11596418 ! positive regulation of axon extension GO:0045773 13 6 0,000 0,03460413 0,11580532 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 0,03460413 0,1156469 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 0,03460413 0,11548892 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,03460413 0,11533136 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,03460413 0,11517423 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 0,03460413 0,11501753 ! forebrain regionalization GO:0021871 9 6 0,000 0,03460413 0,11486126 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,03460413 0,11470541 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,03460413 0,11454998 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 0,03460413 0,11439497 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,03460413 0,11424039 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 0,03460413 0,11408622 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,03460413 0,11393246 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 0,03460413 0,11377912 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 0,03460413 0,11362619 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,03460413 0,11347367 ! malate metabolic process GO:0006108 13 6 0,000 0,03460413 0,11332156 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 0,03460413 0,11316986 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 0,03460413 0,11301856 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 0,03460413 0,11286767 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 0,03460413 0,11271718 ! protein refolding GO:0042026 15 6 0,000 0,03460413 0,11256709 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,03460413 0,1124174 ! opsonization GO:0008228 8 6 0,000 0,03460413 0,11226811 ! mating behavior GO:0007617 7 6 0,000 0,03460413 0,11211921 ! erythrocyte maturation GO:0043249 8 6 0,000 0,03460413 0,11197071 ! embryonic hemopoiesis GO:0035162 16 6 0,000 0,03460413 0,1118226 ! protein amino acid dealkylation GO:0008214 15 6 0,000 0,03460413 0,11167488 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 0,03460413 0,11152755 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 0,03460413 0,11138061 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,03460413 0,11123406 ! response to interferon-gamma GO:0034341 16 6 0,000 0,03460413 0,11108789 ! toxin metabolic process GO:0009404 11 6 0,000 0,03460413 0,11094211 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,03460413 0,11079671 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 0,03460413 0,11065168 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 0,03460413 0,11050704 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 0,03460413 0,11036278 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 13 6 0,000 0,03460413 0,11021889 ! cGMP-mediated signaling GO:0019934 14 6 0,000 0,03460413 0,11007537 ! dorsal spinal cord development GO:0021516 10 6 0,000 0,03460413 0,10993223 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,03460413 0,10978946 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 0,03460413 0,10964706 ! thymic T cell selection GO:0045061 16 6 0,000 0,03460413 0,10950503 ! sphingoid catabolic process GO:0046521 8 6 0,000 0,03460413 0,10936337 ! protein lipoylation GO:0009249 10 6 0,000 0,03460413 0,10922208 ! transepithelial chloride transport GO:0030321 12 6 0,000 0,03460413 0,10908114 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 0,03460413 0,10894058 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,03460413 0,10880037 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 0,03460413 0,10866052 ! glutamate catabolic process GO:0006538 12 6 0,000 0,03460413 0,10852104 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 0,03460413 0,10838191 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,03460413 0,10824313 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 0,03460413 0,10810471 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,03460413 0,10796665 ! hyperosmotic response GO:0006972 10 6 0,000 0,03460413 0,10782894 ! L-serine biosynthetic process GO:0006564 7 6 0,000 0,03460413 0,10769157 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 0,03460413 0,10755456 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 0,03460413 0,1074179 ! urea metabolic process GO:0019627 7 6 0,000 0,03460413 0,10728158 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,03460413 0,10714561 ! neutrophil activation GO:0042119 7 6 0,000 0,03460413 0,10700998 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,03460413 0,1068747 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 0,03460413 0,10673976 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,03460413 0,10660515 ! paraxial mesoderm development GO:0048339 16 6 0,000 0,03460413 0,10647089 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 0,03460413 0,10633696 ! neuron apoptosis GO:0051402 15 6 0,000 0,03460413 0,10620337 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,03460413 0,10607012 ! T cell mediated immunity GO:0002456 17 6 0,000 0,03460413 0,1059372 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,03460413 0,10580461 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 0,03460413 0,10567236 ! carnitine transport GO:0015879 10 6 0,000 0,03460413 0,10554043 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,03460413 0,10540884 ! positive regulation of exocytosis GO:0045921 11 6 0,000 0,03460413 0,10527757 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 0,03460413 0,10514662 ! 5S class rRNA transcription GO:0042791 13 6 0,000 0,03460413 0,10501601 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! neuronal ion channel clustering GO:0045161 15 6 0,000 0,03460413 0,10488572 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 0,03460413 0,10475575 ! sodium ion homeostasis GO:0055078 12 6 0,000 0,03460413 0,1046261 ! establishment of spindle localization GO:0051293 16 6 0,000 0,03460413 0,10449677 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 0,03460413 0,10436776 ! astrocyte development GO:0014002 16 6 0,000 0,03460413 0,10423907 ! protein targeting to lysosome GO:0006622 12 6 0,000 0,03460413 0,1041107 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,03460413 0,10398264 ! interaction with symbiont GO:0051702 14 6 0,000 0,03460413 0,1038549 ! regulation of dendrite development GO:0050773 16 6 0,000 0,03460413 0,10372747 ! peptidyl-arginine modification GO:0018195 13 6 0,000 0,03460413 0,10360035 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 0,03460413 0,10347355 ! response to copper ion GO:0046688 10 6 0,000 0,03460413 0,10334705 ! response to exogenous dsRNA GO:0043330 13 6 0,000 0,03460413 0,10322086 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 0,03460413 0,10309498 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,03460413 0,10296941 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 0,03460413 0,10284414 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,03460413 0,10271918 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 0,03460413 0,10259452 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,03460413 0,10247017 ! nucleoside catabolic process GO:0009164 10 6 0,000 0,03460413 0,10234611 ! hair follicle maturation GO:0048820 8 6 0,000 0,03460413 0,10222235 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,03460413 0,1020989 ! Schwann cell development GO:0014044 15 6 0,000 0,03460413 0,10197574 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 0,03460413 0,10185288 ! response to pheromone GO:0019236 6 6 0,000 0,03460413 0,10173031 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 0,03460413 0,10160804 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 0,03460413 0,10148606 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 0,03460413 0,10136437 ! base conversion or substitution editing GO:0016553 6 6 0,000 0,03460413 0,10124298 ! subpallium development GO:0021544 15 6 0,000 0,03460413 0,10112187 ! neural tube patterning GO:0021532 8 6 0,000 0,03460413 0,10100106 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 0,03460413 0,10088053 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 0,03460413 0,10076029 ! maintenance of organ identity GO:0048496 9 6 0,000 0,03460413 0,10064034 ! G2 phase GO:0051319 16 6 0,000 0,03460413 0,10052067 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 0,03460413 0,10040129 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 0,03460413 0,10028219 ! oxygen homeostasis GO:0032364 10 6 0,000 0,03460413 0,10016337 ! establishment of planar polarity GO:0001736 7 6 0,000 0,03460413 0,10004484 ! regulation of mast cell activation GO:0033003 13 6 0,000 0,03460413 0,09992658 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,03460413 0,0998086 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 0,03460413 0,0996909 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,03460413 0,09957348 ! receptor internalization GO:0031623 11 6 0,000 0,03460413 0,09945634 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 0,03460413 0,09933947 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 0,03460413 0,09922287 ! neutrophil homeostasis GO:0001780 11 6 0,000 0,03460413 0,09910655 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,03460413 0,0989905 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 0,03460413 0,09887472 ! protein deubiquitination GO:0016579 16 6 0,000 0,03460413 0,09875921 ! protein destabilization GO:0031648 9 6 0,000 0,03460413 0,09864397 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 0,03460413 0,09852901 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,03460413 0,0984143 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 0,03460413 0,09829987 ! regulation of viral transcription GO:0046782 11 6 0,000 0,03460413 0,0981857 ! negative regulation of axon extension GO:0030517 24 6 0,000 0,03460413 0,09807179 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 0,03460413 0,09795815 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 0,03460413 0,09784478 ! determination of adult lifespan GO:0008340 17 6 0,000 0,03460413 0,09773166 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 0,03460413 0,09761881 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 0,03460413 0,09750621 ! neural plate development GO:0001840 9 6 0,000 0,03460413 0,09739388 ! catecholamine transport GO:0051937 9 6 0,000 0,03460413 0,0972818 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 0,03460413 0,09716998 ! sensory cilium assembly GO:0035058 10 6 0,000 0,03460413 0,09705842 ! organ or tissue specific immune response GO:0002251 8 6 0,000 0,03460413 0,09694712 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 0,03460413 0,09683607 ! maternal placenta development GO:0001893 12 6 0,000 0,03460413 0,09672527 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 0,03460413 0,09661473 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,03460413 0,09650444 ! negative regulation of B cell activation GO:0050869 14 6 0,000 0,03460413 0,0963944 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 0,03460413 0,09628461 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 0,03460413 0,09617507 ! positive regulation of coagulation GO:0050820 13 6 0,000 0,03460413 0,09606578 ! cellular anion homeostasis GO:0030002 11 6 0,000 0,03460413 0,09595674 GO:0055081|anion homeostasis, ! regulation of action potential GO:0001508 102 50 1,000 0,03474065 0,09622608 ! endocrine system development GO:0035270 109 50 1,000 0,03474065 0,09611711 ! activation of caspase activity GO:0006919 95 50 1,000 0,03474065 0,09600838 ! regulation of ossification GO:0030278 123 50 1,000 0,03474065 0,09589989 ! peptide metabolic process GO:0006518 80 51 1,000 0,03602209 0,09932503 ! detection of abiotic stimulus GO:0009582 80 51 1,000 0,03602209 0,09921305 ! negative regulation of immune system process GO:0002683 101 51 1,000 0,03602209 0,09910132 ! morphogenesis of embryonic epithelium GO:0016331 106 52 1,000 0,03732158 0,10256088 ! DNA-dependent DNA replication GO:0006261 82 52 1,000 0,03732158 0,10244565 ! histone modification GO:0016570 104 52 1,000 0,03732158 0,10233067 ! amino acid activation GO:0043038 98 52 1,000 0,03732158 0,10221595 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! positive regulation of binding GO:0051099 88 52 1,000 0,03732158 0,10210148 ! response to estrogen stimulus GO:0043627 98 52 1,000 0,03732158 0,10198728 ! Notch signaling pathway GO:0007219 111 52 1,000 0,03732158 0,10187332 ! synapse organization GO:0050808 102 53 1,000 0,03863886 0,10535127 ! positive regulation of growth GO:0045927 96 53 1,000 0,03863886 0,10523382 ! regulation of angiogenesis GO:0045765 125 54 1,000 0,03997368 0,10874799 ! activation of phospholipase C activity GO:0007202 110 54 1,000 0,03997368 0,10862702 GO:0010863|positive regulation of phospholipase C activity, ! covalent chromatin modification GO:0016569 115 54 1,000 0,03997368 0,10850633 ! epithelial tube morphogenesis GO:0060562 114 54 1,000 0,03997368 0,1083859 ! tRNA transcription GO:0009304 17 7 0,000 0,04025448 0,10902628 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 0,04025448 0,10890554 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 0,04025448 0,10878507 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,04025448 0,10866487 ! regulation of helicase activity GO:0051095 16 7 0,000 0,04025448 0,10854493 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,04025448 0,10842525 ! sleep GO:0030431 16 7 0,000 0,04025448 0,10830584 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,04025448 0,10818669 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 0,04025448 0,10806781 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,04025448 0,10794918 ! prostate gland development GO:0030850 14 7 0,000 0,04025448 0,10783082 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,04025448 0,10771271 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,04025448 0,10759486 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,04025448 0,10747727 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,04025448 0,10735994 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,04025448 0,10724286 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,04025448 0,10712604 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,04025448 0,10700947 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,04025448 0,10689316 ! SMAD protein complex assembly GO:0007183 13 7 0,000 0,04025448 0,1067771 ! glycolipid transport GO:0046836 11 7 0,000 0,04025448 0,10666129 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,04025448 0,10654573 GO:0051923|sulfation, ! neuron adhesion GO:0007158 14 7 0,000 0,04025448 0,10643042 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,04025448 0,10631536 ! establishment of tissue polarity GO:0007164 8 7 0,000 0,04025448 0,10620055 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 0,04025448 0,10608598 ! mRNA stabilization GO:0048255 18 7 0,000 0,04025448 0,10597167 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 0,04025448 0,10585759 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 0,04025448 0,10574377 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 0,04025448 0,10563019 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 0,04025448 0,10551685 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 0,04025448 0,10540376 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,04025448 0,10529091 ! lipoprotein transport GO:0042953 14 7 0,000 0,04025448 0,10517829 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,04025448 0,10506592 ! rhythmic behavior GO:0007622 17 7 0,000 0,04025448 0,10495379 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 0,04025448 0,1048419 GO:0042069|regulation of catecholamine metabolic process, ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,04025448 0,10473025 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 0,04025448 0,10461884 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,04025448 0,10450766 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,04025448 0,10439671 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 0,04025448 0,10428601 ! mechanosensory behavior GO:0007638 16 7 0,000 0,04025448 0,10417554 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 0,04025448 0,1040653 ! positive regulation of isotype switching GO:0045830 17 7 0,000 0,04025448 0,10395529 GO:0045911|positive regulation of DNA recombination, ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,04025448 0,10384552 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,04025448 0,10373598 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,04025448 0,10362667 ! spinal cord patterning GO:0021511 14 7 0,000 0,04025448 0,10351758 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 0,04025448 0,10340873 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,04025448 0,10330011 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,04025448 0,10319172 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 0,04025448 0,10308355 ! adrenal gland development GO:0030325 17 7 0,000 0,04025448 0,10297561 ! cysteine metabolic process GO:0006534 13 7 0,000 0,04025448 0,10286789 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 0,04025448 0,1027604 ! ovulation GO:0030728 10 7 0,000 0,04025448 0,10265314 ! adenohypophysis development GO:0021984 11 7 0,000 0,04025448 0,1025461 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 0,04025448 0,10243928 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 0,04025448 0,10233268 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline biosynthetic process GO:0006561 10 7 0,000 0,04025448 0,1022263 ! tryptophan metabolic process GO:0006568 11 7 0,000 0,04025448 0,10212015 ! thyroid hormone generation GO:0006590 13 7 0,000 0,04025448 0,10201422 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 0,04025448 0,1019085 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,04025448 0,10180301 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,04025448 0,10169773 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,04025448 0,10159267 ! galactose metabolic process GO:0006012 13 7 0,000 0,04025448 0,10148783 ! vesicle fusion GO:0006906 20 7 0,000 0,04025448 0,1013832 ! response to dietary excess GO:0002021 8 7 0,000 0,04025448 0,10127879 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,04025448 0,10117459 ! intracellular pH reduction GO:0051452 13 7 0,000 0,04025448 0,10107061 GO:0045851|pH reduction, ! melanosome organization GO:0032438 10 7 0,000 0,04025448 0,10096684 ! organ growth GO:0035265 15 7 0,000 0,04025448 0,10086329 ! nucleoside transport GO:0015858 11 7 0,000 0,04025448 0,10075994 ! nucleoside salvage GO:0043174 11 7 0,000 0,04025448 0,10065681 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 0,04025448 0,10055389 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,04025448 0,10045118 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 0,04025448 0,10034868 ! parturition GO:0007567 16 7 0,000 0,04025448 0,10024639 ! rRNA modification GO:0000154 14 7 0,000 0,04025448 0,1001443 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,04025448 0,10004243 ! spindle checkpoint GO:0031577 16 7 0,000 0,04025448 0,09994076 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 0,04025448 0,09983929 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,04025448 0,09973804 ! monocyte differentiation GO:0030224 16 7 0,000 0,04025448 0,09963699 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,04025448 0,09953614 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,04025448 0,0994355 GO:0046676|negative regulation of insulin secretion, ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,04025448 0,09933506 ! G1 DNA damage checkpoint GO:0031571 20 7 0,000 0,04025448 0,09923482 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,04025448 0,09913478 ! fibrinolysis GO:0042730 11 7 0,000 0,04025448 0,09903495 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,04025448 0,09893532 ! eating behavior GO:0042755 8 7 0,000 0,04025448 0,09883588 ! B cell lineage commitment GO:0002326 21 7 0,000 0,04025448 0,09873665 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,04025448 0,09863762 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 0,04025448 0,09853878 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 0,04025448 0,09844015 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,04025448 0,09834171 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 0,04025448 0,09824346 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,04025448 0,09814541 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 0,04025448 0,09804756 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 0,04025448 0,09794991 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,04025448 0,09785244 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 0,04025448 0,09775517 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,04025448 0,0976581 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,04025448 0,09756122 ! histone ubiquitination GO:0016574 9 7 0,000 0,04025448 0,09746452 ! regulation of meiosis GO:0040020 12 7 0,000 0,04025448 0,09736803 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 0,04025448 0,09727172 ! T cell lineage commitment GO:0002360 16 7 0,000 0,04025448 0,0971756 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 0,04025448 0,09707967 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,04025448 0,09698393 ! membrane to membrane docking GO:0022614 14 7 0,000 0,04025448 0,09688838 ! transcription termination GO:0006353 14 7 0,000 0,04025448 0,09679302 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,04025448 0,09669784 ! anaphase GO:0051322 18 7 0,000 0,04025448 0,09660285 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 0,04025448 0,09650805 ! axonal fasciculation GO:0007413 19 7 0,000 0,04025448 0,09641344 ! negative regulation of nuclear division GO:0051784 15 7 0,000 0,04025448 0,09631901 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 0,04025448 0,09622476 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,04025448 0,0961307 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 0,04025448 0,09603682 ! diuresis GO:0030146 12 7 0,000 0,04025448 0,09594313 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,04025448 0,09584962 ! thiamin metabolic process GO:0006772 7 7 0,000 0,04025448 0,09575629 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,04025448 0,09566314 ! antibiotic transport GO:0042891 9 7 0,000 0,04025448 0,09557017 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,04025448 0,09547738 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 0,04025448 0,09538478 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 0,04025448 0,09529235 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 0,04025448 0,0952001 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,04025448 0,09510803 ! melanin biosynthetic process GO:0042438 10 7 0,000 0,04025448 0,09501614 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 0,04025448 0,09492443 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,04025448 0,09483289 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,04025448 0,09474153 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 0,04025448 0,09465034 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,04025448 0,09455933 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 0,04025448 0,0944685 ! endosome to lysosome transport GO:0008333 12 7 0,000 0,04025448 0,09437784 ! protein modification by small protein removal GO:0070646 19 7 0,000 0,04025448 0,09428735 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 0,04025448 0,09419704 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,04025448 0,0941069 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 0,04025448 0,09401693 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,04025448 0,09392713 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,04025448 0,09383751 ! muscle adaptation GO:0043500 13 7 0,000 0,04025448 0,09374805 ! embryonic heart tube development GO:0035050 14 7 0,000 0,04025448 0,09365877 ! retina homeostasis GO:0001895 12 7 0,000 0,04025448 0,09356965 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 0,04025448 0,09348071 ! protein amino acid prenylation GO:0018346 19 7 0,000 0,04025448 0,09339193 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 0,04025448 0,09330333 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 0,04025448 0,09321489 ! positive regulation of phospholipase activity GO:0010518 111 55 1,000 0,04132579 0,09560501 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 1,000 0,04132579 0,09551456 ! cell recognition GO:0008037 98 55 1,000 0,04132579 0,09542429 ! chloride transport GO:0006821 102 57 1,000 0,0440809 0,10168992 ! regulation of bone remodeling GO:0046850 143 57 1,000 0,0440809 0,10159399 ! positive regulation of caspase activity GO:0043280 108 57 1,000 0,0440809 0,10149823 GO:0010952|positive regulation of peptidase activity, ! regulation of phospholipase activity GO:0010517 113 57 1,000 0,0440809 0,10140266 ! heart morphogenesis GO:0003007 105 57 1,000 0,0440809 0,10130727 ! nucleotide-excision repair GO:0006289 91 57 1,000 0,0440809 0,10121206 ! aging GO:0007568 112 58 1,000 0,04548341 0,10433425 ! regulation of tissue remodeling GO:0034103 146 58 1,000 0,04548341 0,10423637 ! positive regulation of lipase activity GO:0060193 115 58 1,000 0,04548341 0,10413868 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,04587193 0,10492989 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,04587193 0,10483173 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 0,04587193 0,10473376 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 0,04587193 0,10463596 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,04587193 0,10453836 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,04587193 0,10444093 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,04587193 0,10434369 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,04587193 0,10424662 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,04587193 0,10414974 ! meiotic prophase I GO:0007128 14 8 0,000 0,04587193 0,10405303 ! response to zinc ion GO:0010043 12 8 0,000 0,04587193 0,10395651 ! regulation of lipid kinase activity GO:0043550 17 8 0,000 0,04587193 0,10386017 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,04587193 0,103764 ! oligopeptide transport GO:0006857 16 8 0,000 0,04587193 0,10366801 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,04587193 0,1035722 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,04587193 0,10347656 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,04587193 0,10338111 ! signal peptide processing GO:0006465 12 8 0,000 0,04587193 0,10328582 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,04587193 0,10319072 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,04587193 0,10309578 ! succinate metabolic process GO:0006105 17 8 0,000 0,04587193 0,10300103 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,04587193 0,10290644 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,04587193 0,10281204 ! estrogen metabolic process GO:0008210 17 8 0,000 0,04587193 0,1027178 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,04587193 0,10262373 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,04587193 0,10252984 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,04587193 0,10243612 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,04587193 0,10234257 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,04587193 0,1022492 ! reflex GO:0060004 17 8 0,000 0,04587193 0,10215599 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,04587193 0,10206295 ! hemoglobin metabolic process GO:0020027 14 8 0,000 0,04587193 0,10197008 ! pigment granule organization GO:0048753 17 8 0,000 0,04587193 0,10187738 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,04587193 0,10178485 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,04587193 0,10169248 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,04587193 0,10160029 ! astrocyte differentiation GO:0048708 19 8 0,000 0,04587193 0,10150826 ! histidine catabolic process GO:0006548 10 8 0,000 0,04587193 0,1014164 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,04587193 0,1013247 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,04587193 0,10123317 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,04587193 0,1011418 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 13 8 0,000 0,04587193 0,1010506 ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,04587193 0,10095957 ! regulation of pigmentation during development GO:0048070 25 8 0,000 0,04587193 0,10086869 ! melanin metabolic process GO:0006582 17 8 0,000 0,04587193 0,10077798 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,04587193 0,10068744 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,04587193 0,10059705 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,04587193 0,10050683 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,04587193 0,10041677 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,04587193 0,10032687 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,04587193 0,10023714 ! purine salvage GO:0043101 12 8 0,000 0,04587193 0,10014756 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,04587193 0,10005814 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,04587193 0,09996888 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,04587193 0,09987978 ! osteoblast development GO:0002076 17 8 0,000 0,04587193 0,09979084 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,04587193 0,09970206 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,04587193 0,09961344 ! Schwann cell differentiation GO:0014037 21 8 0,000 0,04587193 0,09952497 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,04587193 0,09943666 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,04587193 0,09934851 ! response to UV-B GO:0010224 17 8 0,000 0,04587193 0,09926051 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,04587193 0,09917267 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,04587193 0,09908499 ! intermediate filament organization GO:0045109 12 8 0,000 0,04587193 0,09899745 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,04587193 0,09891008 ! cellular extravasation GO:0045123 13 8 0,000 0,04587193 0,09882286 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,04587193 0,09873579 ! response to antibiotic GO:0046677 11 8 0,000 0,04587193 0,09864887 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,04587193 0,09856211 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,04587193 0,0984755 ! DNA topological change GO:0006265 12 8 0,000 0,04587193 0,09838904 ! response to tropane GO:0014073 15 8 0,000 0,04587193 0,09830274 GO:0042220|response to cocaine, ! melanosome transport GO:0032402 13 8 0,000 0,04587193 0,09821658 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,04587193 0,09813058 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,04587193 0,09804472 ! mast cell activation GO:0045576 14 8 0,000 0,04587193 0,09795902 ! multicellular organismal aging GO:0010259 20 8 0,000 0,04587193 0,09787347 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 0,04587193 0,09778806 ! gas homeostasis GO:0033483 14 8 0,000 0,04587193 0,09770281 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,04587193 0,0976177 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,04587193 0,09753274 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,04587193 0,09744793 ! nucleosome disassembly GO:0006337 14 8 0,000 0,04587193 0,09736327 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,04587193 0,09727875 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 0,04587193 0,09719438 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,04587193 0,09711015 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,04587193 0,09702608 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,04587193 0,09694214 ! intracellular lipid transport GO:0032365 16 8 0,000 0,04587193 0,09685836 ! response to tumor cell GO:0002347 16 8 0,000 0,04587193 0,09677471 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,04587193 0,09669122 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,04587193 0,09660786 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 0,04587193 0,09652465 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,04587193 0,09644158 ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,04587193 0,09635866 ! hormone catabolic process GO:0042447 17 8 0,000 0,04587193 0,09627587 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,04587193 0,09619323 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,04587193 0,09611074 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,04587193 0,09602838 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,04587193 0,09594616 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,04587193 0,09586409 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,04587193 0,09578215 ! adult feeding behavior GO:0008343 10 8 0,000 0,04587193 0,09570036 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,04587193 0,0956187 ! ATP catabolic process GO:0006200 11 8 0,000 0,04587193 0,09553719 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,04587193 0,09545581 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,04587193 0,09537457 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,04587193 0,09529347 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,04587193 0,0952125 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,04587193 0,09513168 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,04587193 0,09505099 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,04587193 0,09497044 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,04587193 0,09489002 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,04587193 0,09480974 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 0,04587193 0,0947296 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,04587193 0,09464959 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 0,04587193 0,09456972 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,04587193 0,09448998 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 0,04587193 0,09441038 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 0,04587193 0,09433091 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,04587193 0,09425157 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,04587193 0,09417237 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 0,04587193 0,0940933 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 0,04587193 0,09401436 ! DNA catabolic process GO:0006308 94 60 1,000 0,04833717 0,09898382 ! kidney development GO:0001822 133 60 1,000 0,04833717 0,09890092 ! cytokine-mediated signaling pathway GO:0019221 112 61 1,000 0,04978794 0,10178404 ! camera-type eye development GO:0043010 126 61 1,000 0,04978794 0,10169894 ! viral reproductive process GO:0022415 132 62 1,000 0,05125432 0,10460678 ! regulation of homeostatic process GO:0032844 148 62 1,000 0,05125432 0,10451946 ! DNA damage response, signal transduction GO:0042770 136 62 1,000 0,05125432 0,10443229 ! axon extension GO:0048675 16 9 0,000 0,05145665 0,10475716 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,05145665 0,10466993 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 0,05145665 0,10458285 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,05145665 0,10449592 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,05145665 0,10440913 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,05145665 0,10432248 ! reproductive behavior GO:0019098 22 9 0,000 0,05145665 0,10423598 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,05145665 0,10414962 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 0,05145665 0,1040634 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 0,05145665 0,10397733 ! UTP metabolic process GO:0046051 10 9 0,000 0,05145665 0,1038914 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,05145665 0,10380561 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,05145665 0,10371996 ! artery development GO:0060840 25 9 0,000 0,05145665 0,10363445 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,05145665 0,10354909 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,05145665 0,10346386 ! equilibrioception GO:0050957 20 9 0,000 0,05145665 0,10337878 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,05145665 0,10329383 ! chemosensory behavior GO:0007635 21 9 0,000 0,05145665 0,10320902 ! microtubule bundle formation GO:0001578 22 9 0,000 0,05145665 0,10312436 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,05145665 0,10303983 ! leukocyte degranulation GO:0043299 16 9 0,000 0,05145665 0,10295544 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,05145665 0,10287119 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,05145665 0,10278707 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,05145665 0,1027031 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,05145665 0,10261926 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,05145665 0,10253556 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,05145665 0,10245199 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,05145665 0,10236856 ! protein targeting to ER GO:0045047 25 9 0,000 0,05145665 0,10228527 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,05145665 0,10220211 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 0,05145665 0,10211908 ! T cell selection GO:0045058 27 9 0,000 0,05145665 0,10203619 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,05145665 0,10195344 ! glycine catabolic process GO:0006546 15 9 0,000 0,05145665 0,10187082 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,05145665 0,10178833 ! endosome organization GO:0007032 20 9 0,000 0,05145665 0,10170598 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,05145665 0,10162376 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,05145665 0,10154167 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,05145665 0,10145972 ! mannose metabolic process GO:0006013 13 9 0,000 0,05145665 0,1013779 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,05145665 0,10129621 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,05145665 0,10121465 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 0,05145665 0,10113322 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,05145665 0,10105192 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,05145665 0,10097076 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,05145665 0,10088972 ! retinol metabolic process GO:0042572 20 9 0,000 0,05145665 0,10080881 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,05145665 0,10072804 ! macrophage differentiation GO:0030225 15 9 0,000 0,05145665 0,10064739 ! oligodendrocyte development GO:0014003 11 9 0,000 0,05145665 0,10056687 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 0,05145665 0,10048648 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,05145665 0,10040622 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,05145665 0,10032609 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,05145665 0,10024609 ! response to amine stimulus GO:0014075 13 9 0,000 0,05145665 0,10016621 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,05145665 0,10008646 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,05145665 0,10000683 ! erythrocyte development GO:0048821 17 9 0,000 0,05145665 0,09992734 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,05145665 0,09984797 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,05145665 0,09976872 ! renal water homeostasis GO:0003091 15 9 0,000 0,05145665 0,0996896 ! postreplication repair GO:0006301 25 9 0,000 0,05145665 0,09961061 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,05145665 0,09953174 ! icosanoid secretion GO:0032309 15 9 0,000 0,05145665 0,099453 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,05145665 0,09937438 GO:0021696|cerebellar cortex morphogenesis, ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,05145665 0,09929589 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,05145665 0,09921751 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,05145665 0,09913927 ! sterol catabolic process GO:0016127 14 9 0,000 0,05145665 0,09906114 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,05145665 0,09898314 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,05145665 0,09890526 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,05145665 0,09882751 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,05145665 0,09874988 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 0,05145665 0,09867236 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,05145665 0,09859497 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 0,05145665 0,0985177 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,05145665 0,09844056 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,05145665 0,09836353 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,05145665 0,09828662 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,05145665 0,09820984 ! purine base metabolic process GO:0006144 25 9 0,000 0,05145665 0,09813317 ! pigment granule transport GO:0051904 17 9 0,000 0,05145665 0,09805662 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,05145665 0,0979802 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,05145665 0,09790389 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,05145665 0,0978277 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,05145665 0,09775163 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,05145665 0,09767567 ! mitochondrion localization GO:0051646 18 9 0,000 0,05145665 0,09759984 ! regulation of mitosis GO:0007088 112 63 1,000 0,0527361 0,09994902 GO:0051783|regulation of nuclear division, ! mesoderm development GO:0007498 128 63 1,000 0,0527361 0,09987154 ! glycerophospholipid biosynthetic process GO:0046474 116 64 1,000 0,05423303 0,10262686 ! nucleoside monophosphate metabolic process GO:0009123 117 65 1,000 0,05574489 0,10540616 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,05700884 0,10771275 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,05700884 0,10762951 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,05700884 0,1075464 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,05700884 0,10746342 ! associative learning GO:0008306 21 10 0,000 0,05700884 0,10738056 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,05700884 0,10729783 ! phosphate transport GO:0006817 24 10 0,000 0,05700884 0,10721523 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,05700884 0,10713276 ! CTP metabolic process GO:0046036 11 10 0,000 0,05700884 0,10705041 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 0,05700884 0,10696819 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,05700884 0,1068861 ! GTP metabolic process GO:0046039 11 10 0,000 0,05700884 0,10680413 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,05700884 0,10672229 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,05700884 0,10664057 ! social behavior GO:0035176 29 10 0,000 0,05700884 0,10655898 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,05700884 0,10647751 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,05700884 0,10639617 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,05700884 0,10631495 ! androgen metabolic process GO:0008209 17 10 0,000 0,05700884 0,10623386 ! phospholipid efflux GO:0033700 19 10 0,000 0,05700884 0,10615289 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,05700884 0,10607204 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,05700884 0,10599131 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,05700884 0,10591071 ! lung alveolus development GO:0048286 26 10 0,000 0,05700884 0,10583023 ! pathogenesis GO:0009405 17 10 0,000 0,05700884 0,10574988 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,05700884 0,10566964 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,05700884 0,10558953 ! endoderm development GO:0007492 18 10 0,000 0,05700884 0,10550954 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,05700884 0,10542967 ! arginine catabolic process GO:0006527 17 10 0,000 0,05700884 0,10534992 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,05700884 0,10527029 ! proline metabolic process GO:0006560 13 10 0,000 0,05700884 0,10519078 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,05700884 0,10511139 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 0,05700884 0,10503212 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,05700884 0,10495297 ! V(D)J recombination GO:0033151 34 10 0,000 0,05700884 0,10487394 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,05700884 0,10479502 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,05700884 0,10471623 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,05700884 0,10463756 ! B cell proliferation GO:0042100 19 10 0,000 0,05700884 0,104559 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,05700884 0,10448056 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,05700884 0,10440224 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,05700884 0,10432404 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,05700884 0,10424595 ! ruffle organization GO:0031529 17 10 0,000 0,05700884 0,10416798 ! epithelial cell development GO:0002064 21 10 0,000 0,05700884 0,10409013 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,05700884 0,10401239 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,05700884 0,10393477 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,05700884 0,10385726 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,05700884 0,10377987 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,05700884 0,1037026 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,05700884 0,10362544 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 13 10 0,000 0,05700884 0,10354839 ! regulation of bone resorption GO:0045124 25 10 0,000 0,05700884 0,10347146 ! brain morphogenesis GO:0048854 23 10 0,000 0,05700884 0,10339465 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,05700884 0,10331794 ! segment specification GO:0007379 15 10 0,000 0,05700884 0,10324135 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,05700884 0,10316488 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,05700884 0,10308852 ! response to dsRNA GO:0043331 23 10 0,000 0,05700884 0,10301227 ! DNA ligation GO:0006266 18 10 0,000 0,05700884 0,10293613 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,05700884 0,10286011 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,05700884 0,1027842 ! melanosome localization GO:0032400 16 10 0,000 0,05700884 0,1027084 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,05700884 0,10263271 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,05700884 0,10255713 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,05700884 0,10248167 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,05700884 0,10240631 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,05700884 0,10233107 ! induction of an organ GO:0001759 17 10 0,000 0,05700884 0,10225594 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,05700884 0,10218092 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,05700884 0,102106 ! protein sumoylation GO:0016925 17 10 0,000 0,05700884 0,1020312 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,05700884 0,10195651 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,05700884 0,10188192 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,05700884 0,10180745 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,05700884 0,10173308 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,05700884 0,10165882 ! salivary gland development GO:0007431 28 10 0,000 0,05700884 0,10158467 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,05700884 0,10151063 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,05700884 0,1014367 ! midbrain development GO:0030901 14 10 0,000 0,05700884 0,10136287 ! musculoskeletal movement GO:0050881 16 10 0,000 0,05700884 0,10128915 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,05700884 0,10121554 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,05700884 0,10114204 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,05700884 0,10106864 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,05700884 0,10099535 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,05700884 0,10092216 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,05700884 0,10084909 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,05700884 0,10077611 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,05700884 0,10070324 ! detection of calcium ion GO:0005513 24 10 0,000 0,05700884 0,10063048 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,05700884 0,10055783 ! blastocyst formation GO:0001825 18 10 0,000 0,05700884 0,10048527 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,05700884 0,10041282 ! cerebellar cortex development GO:0021695 16 10 0,000 0,05700884 0,10034048 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,05700884 0,10026824 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,05700884 0,10019611 ! response to nicotine GO:0035094 20 10 0,000 0,05700884 0,10012407 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,05700884 0,10005215 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,05700884 0,09998032 ! negative regulation of cell growth GO:0030308 142 67 1,000 0,05881251 0,10306956 ! activation of MAPK activity GO:0000187 124 67 1,000 0,05881251 0,10299567 ! embryonic limb morphogenesis GO:0030326 139 67 1,000 0,05881251 0,10292189 GO:0035113|embryonic appendage morphogenesis, ! myeloid cell differentiation GO:0030099 126 67 1,000 0,05881251 0,10284822 ! extracellular matrix organization GO:0030198 146 68 1,000 0,06036783 0,10549257 ! detection of external stimulus GO:0009581 102 68 1,000 0,06036783 0,10541716 ! viral reproduction GO:0016032 142 68 1,000 0,06036783 0,10534186 ! regulation of lipase activity GO:0060191 137 68 1,000 0,06036783 0,10526667 ! adaptive immune response GO:0002250 126 68 1,000 0,06036783 0,10519159 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! cell projection assembly GO:0030031 138 68 1,000 0,06036783 0,10511661 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 1,000 0,06036783 0,10504174 ! negative regulation of cell size GO:0045792 144 69 1,000 0,0619372 0,10769578 ! cellular hormone metabolic process GO:0034754 120 69 1,000 0,0619372 0,10761918 ! urogenital system development GO:0001655 149 69 1,000 0,0619372 0,10754269 ! homeostasis of number of cells GO:0048872 131 69 1,000 0,0619372 0,10746631 ! respiratory burst GO:0045730 17 11 0,000 0,06252868 0,10841559 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,06252868 0,1083387 ! neuron fate specification GO:0048665 18 11 0,000 0,06252868 0,10826192 ! telencephalon cell migration GO:0022029 23 11 0,000 0,06252868 0,10818525 ! thyroid gland development GO:0030878 26 11 0,000 0,06252868 0,10810868 ! synapsis GO:0007129 14 11 0,000 0,06252868 0,10803223 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,06252868 0,10795588 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,06252868 0,10787964 ! response to pain GO:0048265 27 11 0,000 0,06252868 0,10780351 ! keratinocyte proliferation GO:0043616 19 11 0,000 0,06252868 0,10772748 ! blood vessel remodeling GO:0001974 30 11 0,000 0,06252868 0,10765156 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 0,000 0,06252868 0,10757575 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 23 11 0,000 0,06252868 0,10750005 ! bone resorption GO:0045453 16 11 0,000 0,06252868 0,10742445 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,06252868 0,10734896 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,06252868 0,10727357 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,06252868 0,10719829 ! melanocyte differentiation GO:0030318 20 11 0,000 0,06252868 0,10712312 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,06252868 0,10704805 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,06252868 0,10697309 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,06252868 0,10689823 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,06252868 0,10682347 ! regulation of intracellular pH GO:0051453 21 11 0,000 0,06252868 0,10674882 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,06252868 0,10667428 ! UV protection GO:0009650 20 11 0,000 0,06252868 0,10659984 ! adult heart development GO:0007512 16 11 0,000 0,06252868 0,1065255 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,06252868 0,10645127 ! macroautophagy GO:0016236 19 11 0,000 0,06252868 0,10637714 ! temperature homeostasis GO:0001659 18 11 0,000 0,06252868 0,10630311 ! behavioral fear response GO:0001662 27 11 0,000 0,06252868 0,10622919 GO:0002209|behavioral defense response, ! negative regulation of ossification GO:0030279 27 11 0,000 0,06252868 0,10615536 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,06252868 0,10608164 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,06252868 0,10600803 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,06252868 0,10593451 ! regulation of organ growth GO:0046620 14 11 0,000 0,06252868 0,1058611 ! pigment granule localization GO:0051875 20 11 0,000 0,06252868 0,10578779 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,06252868 0,10571458 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,06252868 0,10564147 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,06252868 0,10556846 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,06252868 0,10549556 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,06252868 0,10542275 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,06252868 0,10535005 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,06252868 0,10527744 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,06252868 0,10520494 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,06252868 0,10513253 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,06252868 0,10506023 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,06252868 0,10498802 ! prophase GO:0051324 17 11 0,000 0,06252868 0,10491591 ! nucleosome positioning GO:0016584 15 11 0,000 0,06252868 0,1048439 ! regulation of isotype switching GO:0045191 24 11 0,000 0,06252868 0,10477199 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,06252868 0,10470018 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,06252868 0,10462847 ! apical protein localization GO:0045176 18 11 0,000 0,06252868 0,10455686 ! acid secretion GO:0046717 20 11 0,000 0,06252868 0,10448534 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,06252868 0,10441392 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,06252868 0,1043426 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,06252868 0,10427138 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,06252868 0,10420025 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,06252868 0,10412922 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! cholesterol efflux GO:0033344 21 11 0,000 0,06252868 0,10405829 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,06252868 0,10398745 ! germ cell migration GO:0008354 26 11 0,000 0,06252868 0,10391671 ! embryonic gut development GO:0048566 19 11 0,000 0,06252868 0,10384607 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,06252868 0,10377552 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,06252868 0,10370507 ! activation of innate immune response GO:0002218 16 11 0,000 0,06252868 0,10363471 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,06252868 0,10356445 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,06252868 0,10349429 ! lysogeny GO:0030069 22 11 0,000 0,06252868 0,10342422 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,06252868 0,10335424 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,06252868 0,10328436 ! sequestering of metal ion GO:0051238 15 11 0,000 0,06252868 0,10321457 ! nucleus localization GO:0051647 22 11 0,000 0,06252868 0,10314488 ! cell cycle checkpoint GO:0000075 145 71 1,000 0,06511721 0,10734234 ! cAMP-mediated signaling GO:0019933 124 71 1,000 0,06511721 0,10726996 ! appendage morphogenesis GO:0035107 150 72 1,000 0,06672744 0,10984847 GO:0035108|limb morphogenesis, ! carbohydrate transport GO:0008643 114 72 1,000 0,06672744 0,1097745 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,06801637 0,11181964 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,06801637 0,11174445 ! mating GO:0007618 17 12 0,000 0,06801637 0,11166935 ! protein complex disassembly GO:0043241 28 12 0,000 0,06801637 0,11159435 GO:0043624|cellular protein complex disassembly, ! regulation of cell projection assembly GO:0060491 33 12 0,000 0,06801637 0,11151946 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,06801637 0,11144466 ! T cell proliferation GO:0042098 32 12 0,000 0,06801637 0,11136997 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,06801637 0,11129537 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,06801637 0,11122088 ! ventral spinal cord development GO:0021517 25 12 0,000 0,06801637 0,11114648 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,06801637 0,11107219 ! drug transport GO:0015893 16 12 0,000 0,06801637 0,11099799 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,06801637 0,11092389 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,06801637 0,11084989 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,06801637 0,11077599 ! polyamine metabolic process GO:0006595 18 12 0,000 0,06801637 0,11070219 ! mitotic spindle organization GO:0007052 23 12 0,000 0,06801637 0,11062849 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,06801637 0,11055488 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,06801637 0,11048138 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,06801637 0,11040797 ! lipid digestion GO:0044241 21 12 0,000 0,06801637 0,11033466 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,06801637 0,11026144 ! entry into host cell GO:0030260 34 12 0,000 0,06801637 0,11018832 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,06801637 0,1101153 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,06801637 0,11004238 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,06801637 0,10996955 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,06801637 0,10989682 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,06801637 0,10982418 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,06801637 0,10975165 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,06801637 0,1096792 ! snRNA metabolic process GO:0016073 30 12 0,000 0,06801637 0,10960685 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,06801637 0,1095346 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,06801637 0,10946244 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,06801637 0,10939038 ! fucose catabolic process GO:0019317 25 12 0,000 0,06801637 0,10931842 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,06801637 0,10924654 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,06801637 0,10917476 ! zymogen activation GO:0031638 18 12 0,000 0,06801637 0,10910308 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,06801637 0,10903149 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,06801637 0,10895999 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,06801637 0,10888859 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,06801637 0,10881728 ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 0,000 0,06801637 0,10874607 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,06801637 0,10867495 ! defense response to fungus GO:0050832 15 12 0,000 0,06801637 0,10860392 ! developmental induction GO:0031128 22 12 0,000 0,06801637 0,10853298 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 21 12 0,000 0,06801637 0,10846214 ! lamellipodium assembly GO:0030032 24 12 0,000 0,06801637 0,10839138 ! response to cold GO:0009409 17 12 0,000 0,06801637 0,10832072 ! establishment of cell polarity GO:0030010 21 12 0,000 0,06801637 0,10825016 ! regulation of synapse organization GO:0050807 18 12 0,000 0,06801637 0,10817968 ! appendage development GO:0048736 151 73 1,000 0,06835086 0,10864095 GO:0060173|limb development, ! glycerolipid biosynthetic process GO:0045017 130 73 1,000 0,06835086 0,10857031 ! organelle localization GO:0051640 155 74 1,000 0,06998726 0,11109739 ! eye development GO:0001654 155 75 1,000 0,07163645 0,11364146 ! cell-matrix adhesion GO:0007160 181 76 1,000 0,07329822 0,11620218 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 1,000 0,07329822 0,11612682 ! regulation of blood pressure GO:0008217 134 76 1,000 0,07329822 0,11605156 ! lymphocyte differentiation GO:0030098 193 76 1,000 0,07329822 0,1159764 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,07347209 0,11617625 ! cGMP metabolic process GO:0046068 18 13 0,000 0,07347209 0,11610111 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,07347209 0,11602606 ! regulation of chemokine production GO:0032642 18 13 0,000 0,07347209 0,11595111 ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,07347209 0,11587625 ! peroxisomal transport GO:0043574 28 13 0,000 0,07347209 0,11580149 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,07347209 0,11572683 ! cartilage condensation GO:0001502 22 13 0,000 0,07347209 0,11565226 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,07347209 0,11557779 ! organelle fusion GO:0048284 36 13 0,000 0,07347209 0,11550342 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,07347209 0,11542914 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,07347209 0,11535496 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,07347209 0,11528087 ! endocrine pancreas development GO:0031018 25 13 0,000 0,07347209 0,11520688 ! positive regulation of cell growth GO:0030307 24 13 0,000 0,07347209 0,11513298 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,07347209 0,11505917 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,07347209 0,11498547 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,07347209 0,11491185 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,07347209 0,11483833 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,07347209 0,11476491 ! methionine metabolic process GO:0006555 31 13 0,000 0,07347209 0,11469157 ! plasma membrane organization GO:0007009 27 13 0,000 0,07347209 0,11461833 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,07347209 0,11454519 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,07347209 0,11447214 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,07347209 0,11439918 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,07347209 0,11432631 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! cytokine metabolic process GO:0042107 24 13 0,000 0,07347209 0,11425354 ! cellular carbohydrate catabolic process GO:0044275 17 13 0,000 0,07347209 0,11418086 ! exocrine system development GO:0035272 34 13 0,000 0,07347209 0,11410827 ! asymmetric protein localization GO:0008105 24 13 0,000 0,07347209 0,11403578 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,07347209 0,11396337 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 0,07347209 0,11389106 ! L-glutamate transport GO:0015813 30 13 0,000 0,07347209 0,11381884 GO:0015800|acidic amino acid transport, ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,07347209 0,11374671 ! protein homotetramerization GO:0051289 24 13 0,000 0,07347209 0,11367468 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,07347209 0,11360273 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,07347209 0,11353087 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,07347209 0,11345911 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,07347209 0,11338744 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,07347209 0,11331585 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,07347209 0,11324436 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,07347209 0,11317296 ! histone methylation GO:0016571 29 13 0,000 0,07347209 0,11310165 ! chromatin silencing GO:0006342 29 13 0,000 0,07347209 0,11303042 ! gland morphogenesis GO:0022612 31 13 0,000 0,07347209 0,11295929 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,07347209 0,11288825 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 0,07347209 0,11281729 ! regulation of epidermis development GO:0045682 19 13 0,000 0,07347209 0,11274643 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,07347209 0,11267565 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,07347209 0,11260496 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,07347209 0,11253436 ! regulation of mRNA stability GO:0043488 32 13 0,000 0,07347209 0,11246385 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,07347209 0,11239343 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,07347209 0,1123231 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,07347209 0,11225285 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,07347209 0,11218269 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,07347209 0,11211262 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,07347209 0,11204264 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,07347209 0,11197275 ! insulin secretion GO:0030073 24 13 0,000 0,07347209 0,11190294 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,07347209 0,11183322 ! acrosome reaction GO:0007340 19 13 0,000 0,07347209 0,11176358 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,07347209 0,11169403 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,07347209 0,11162457 ! cytosolic calcium ion homeostasis GO:0051480 149 77 1,000 0,07497237 0,11383312 ! positive regulation of lymphocyte activation GO:0051251 142 78 1,000 0,07665869 0,11632123 ! steroid biosynthetic process GO:0006694 146 79 1,000 0,07835699 0,11882441 ! rRNA transcription GO:0009303 28 14 0,000 0,07889602 0,11956761 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,07889602 0,11949348 GO:0046579|positive regulation of Ras protein signal transduction, ! water transport GO:0006833 21 14 0,000 0,07889602 0,11941944 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,07889602 0,1193455 ! non-recombinational repair GO:0000726 29 14 0,000 0,07889602 0,11927165 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,07889602 0,11919789 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,07889602 0,11912422 ! hair follicle morphogenesis GO:0031069 27 14 0,000 0,07889602 0,11905064 ! RNA polyadenylation GO:0043631 32 14 0,000 0,07889602 0,11897715 ! lipid localization GO:0010876 32 14 0,000 0,07889602 0,11890375 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 0,07889602 0,11883045 ! regulated secretory pathway GO:0045055 24 14 0,000 0,07889602 0,11875723 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,07889602 0,1186841 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,07889602 0,11861107 ! arginine metabolic process GO:0006525 21 14 0,000 0,07889602 0,11853812 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,07889602 0,11846526 ! fear response GO:0042596 34 14 0,000 0,07889602 0,1183925 ! organic alcohol transport GO:0015850 29 14 0,000 0,07889602 0,11831982 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,07889602 0,11824723 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 0,000 0,07889602 0,11817473 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,07889602 0,11810232 ! neutral amino acid transport GO:0015804 28 14 0,000 0,07889602 0,11803 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,07889602 0,11795776 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,07889602 0,11788562 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,07889602 0,11781356 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,07889602 0,11774159 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,07889602 0,11766971 ! regulation of cellular pH GO:0030641 27 14 0,000 0,07889602 0,11759792 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,07889602 0,11752621 ! ribosome assembly GO:0042255 18 14 0,000 0,07889602 0,11745459 ! cerebellum development GO:0021549 23 14 0,000 0,07889602 0,11738306 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,07889602 0,11731161 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,07889602 0,11724026 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,07889602 0,11716899 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,07889602 0,1170978 ! NADP metabolic process GO:0006739 24 14 0,000 0,07889602 0,1170267 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,07889602 0,11695569 ! oxygen transport GO:0015671 22 14 0,000 0,07889602 0,11688477 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,07889602 0,11681393 ! male genitalia development GO:0030539 26 14 0,000 0,07889602 0,11674318 ! regulation of RNA stability GO:0043487 33 14 0,000 0,07889602 0,11667251 ! regulation of axon extension GO:0030516 43 14 0,000 0,07889602 0,11660193 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,07889602 0,11653143 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 0,07889602 0,11646102 ! response to hypoxia GO:0001666 178 81 1,000 0,08178874 0,12065815 ! cell-substrate adhesion GO:0031589 189 82 1,000 0,08352181 0,12314048 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,08428836 0,12419569 ! lactation GO:0007595 30 15 0,000 0,08428836 0,12412083 ! reproductive cellular process GO:0048610 22 15 0,000 0,08428836 0,12404606 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,08428836 0,12397138 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,08428836 0,12389678 ! superoxide anion generation GO:0042554 22 15 0,000 0,08428836 0,12382228 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,08428836 0,12374787 ! negative regulation of bone remodeling GO:0046851 34 15 0,000 0,08428836 0,12367355 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,08428836 0,12359931 ! copper ion transport GO:0006825 22 15 0,000 0,08428836 0,12352517 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,08428836 0,12345111 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,08428836 0,12337715 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,08428836 0,12330327 ! sulfate transport GO:0008272 27 15 0,000 0,08428836 0,12322948 ! response to cAMP GO:0051591 25 15 0,000 0,08428836 0,12315577 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,08428836 0,12308216 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,08428836 0,12300864 ! response to hexose stimulus GO:0009746 25 15 0,000 0,08428836 0,1229352 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,08428836 0,12286185 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,08428836 0,12278858 ! vesicle coating GO:0006901 38 15 0,000 0,08428836 0,12271541 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 0,000 0,08428836 0,12264232 ! regulation of exocytosis GO:0017157 26 15 0,000 0,08428836 0,12256932 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,08428836 0,1224964 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,08428836 0,12242358 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,08428836 0,12235083 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,08428836 0,12227818 ! regulation of vasodilation GO:0042312 27 15 0,000 0,08428836 0,12220561 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,08428836 0,12213313 ! histone deacetylation GO:0016575 24 15 0,000 0,08428836 0,12206073 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,08428836 0,12198842 ! water homeostasis GO:0030104 28 15 0,000 0,08428836 0,1219162 ! cofactor transport GO:0051181 30 15 0,000 0,08428836 0,12184406 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,08428836 0,121772 ! muscle maintenance GO:0046716 26 15 0,000 0,08428836 0,12170003 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,08428836 0,12162815 ! intestinal absorption GO:0050892 31 15 0,000 0,08428836 0,12155635 ! dopamine metabolic process GO:0042417 35 15 0,000 0,08428836 0,12148463 ! heme biosynthetic process GO:0006783 33 15 0,000 0,08428836 0,121413 ! cell killing GO:0001906 32 15 0,000 0,08428836 0,12134146 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,08428836 0,12127 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,08428836 0,12119862 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,08428836 0,12112733 ! actin filament polymerization GO:0030041 27 15 0,000 0,08428836 0,12105612 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,08428836 0,12098499 ! regulation of adenylate cyclase activity GO:0045761 165 83 1,000 0,08526608 0,12231651 ! response to oxygen levels GO:0070482 183 83 1,000 0,08526608 0,12224473 ! cellular lipid catabolic process GO:0044242 150 83 1,000 0,08526608 0,12217303 ! intracellular protein transmembrane transport GO:0065002 165 83 1,000 0,08526608 0,12210142 ! inorganic anion transport GO:0015698 156 83 1,000 0,08526608 0,12202989 ! T cell activation GO:0042110 189 84 1,000 0,08702136 0,12446908 ! response to nutrient GO:0007584 135 84 1,000 0,08702136 0,12439624 ! negative regulation of growth GO:0045926 168 85 1,000 0,08878747 0,12684666 ! regulation of cyclase activity GO:0031279 168 85 1,000 0,08878747 0,12677253 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,08964927 0,12792826 ! positive regulation of cell size GO:0045793 29 16 0,000 0,08964927 0,12785358 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,08964927 0,12777898 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,08964927 0,12770448 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,08964927 0,12763006 ! bone remodeling GO:0046849 28 16 0,000 0,08964927 0,12755572 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,08964927 0,12748148 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,08964927 0,12740732 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,08964927 0,12733324 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,08964927 0,12725925 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,08964927 0,12718535 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,08964927 0,12711154 ! startle response GO:0001964 28 16 0,000 0,08964927 0,1270378 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,08964927 0,12696416 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,08964927 0,1268906 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,08964927 0,12681713 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,08964927 0,12674374 ! protein polyubiquitination GO:0000209 41 16 0,000 0,08964927 0,12667043 ! glutamate metabolic process GO:0006536 25 16 0,000 0,08964927 0,12659721 ! response to osmotic stress GO:0006970 27 16 0,000 0,08964927 0,12652408 ! lysosomal transport GO:0007041 31 16 0,000 0,08964927 0,12645103 ! fructose metabolic process GO:0006000 25 16 0,000 0,08964927 0,12637806 ! L-amino acid transport GO:0015807 33 16 0,000 0,08964927 0,12630518 ! stem cell development GO:0048864 46 16 0,000 0,08964927 0,12623238 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,08964927 0,12615966 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,08964927 0,12608703 ! intermediate filament-based process GO:0045103 36 16 0,000 0,08964927 0,12601449 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,08964927 0,12594202 ! negative regulation of immune response GO:0050777 38 16 0,000 0,08964927 0,12586964 ! axon cargo transport GO:0008088 46 16 0,000 0,08964927 0,12579734 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,08964927 0,12572513 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,08964927 0,125653 ! DNA replication initiation GO:0006270 28 16 0,000 0,08964927 0,12558095 ! mRNA splice site selection GO:0006376 44 16 0,000 0,08964927 0,12550898 ! tissue regeneration GO:0042246 27 16 0,000 0,08964927 0,1254371 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,08964927 0,1253653 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,08964927 0,12529358 ! negative regulation of tissue remodeling GO:0034104 37 16 0,000 0,08964927 0,12522194 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,08964927 0,12515039 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,08964927 0,12507891 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,08964927 0,12500752 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,08964927 0,12493621 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,08964927 0,12486498 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,08964927 0,12479383 ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,08964927 0,12472277 ! peptide hormone processing GO:0016486 27 16 0,000 0,08964927 0,12465178 ! regulation of cAMP biosynthetic process GO:0030817 173 86 1,000 0,09056423 0,12585234 ! regulation of lyase activity GO:0051339 169 86 1,000 0,09056423 0,12578079 ! positive regulation of cell activation GO:0050867 161 86 1,000 0,09056423 0,12570932 GO:0002696|positive regulation of leukocyte activation, ! mitochondrion organization GO:0007005 159 87 1,000 0,09235144 0,1281173 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,09497896 0,13168762 ! metencephalon development GO:0022037 32 17 0,000 0,09497896 0,13161293 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,09497896 0,13153832 ! negative regulation of cell cycle process GO:0010948 35 17 0,000 0,09497896 0,13146379 ! filopodium assembly GO:0046847 42 17 0,000 0,09497896 0,13138935 ! endothelial cell migration GO:0043542 31 17 0,000 0,09497896 0,13131499 ! gene silencing by RNA GO:0031047 38 17 0,000 0,09497896 0,13124072 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,09497896 0,13116653 ! glial cell development GO:0021782 28 17 0,000 0,09497896 0,13109242 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,09497896 0,1310184 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,09497896 0,13094446 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 0,000 0,09497896 0,13087061 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,09497896 0,13079684 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,09497896 0,13072315 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 0,000 0,09497896 0,13064954 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,09497896 0,13057602 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,09497896 0,13050258 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,09497896 0,13042922 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,09497896 0,13035595 ! negative regulation of microtubule depolymerization GO:0007026 50 17 0,000 0,09497896 0,13028276 GO:0031114|regulation of microtubule depolymerization, ! NAD metabolic process GO:0019674 33 17 0,000 0,09497896 0,13020965 ! membrane budding GO:0006900 42 17 0,000 0,09497896 0,13013662 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,09497896 0,13006367 ! regulation of protein binding GO:0043393 33 17 0,000 0,09497896 0,12999081 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,09497896 0,12991802 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,09497896 0,12984532 ! genitalia development GO:0048806 32 17 0,000 0,09497896 0,1297727 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,09497896 0,12970016 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,09497896 0,1296277 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,09497896 0,12955533 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,09497896 0,12948303 ! steroid catabolic process GO:0006706 34 17 0,000 0,09497896 0,12941081 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,09497896 0,12933868 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,09497896 0,12926662 ! gas transport GO:0015669 26 17 0,000 0,09497896 0,12919465 ! organic cation transport GO:0015695 32 17 0,000 0,09497896 0,12912275 ! negative regulation of homeostatic process GO:0032845 36 17 0,000 0,09497896 0,12905094 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,09497896 0,1289792 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,09497896 0,12890755 ! regulation of cAMP metabolic process GO:0030814 182 89 1,000 0,09595652 0,13016201 ! tube morphogenesis GO:0035239 194 89 1,000 0,09595652 0,13008978 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 1,000 0,09960128 0,13495614 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! positive regulation of protein complex assembly GO:0031334 34 18 0,000 0,10027758 0,13579719 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,10027758 0,13572196 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,10027758 0,13564681 ! negative regulation of ion transport GO:0043271 25 18 0,000 0,10027758 0,13557174 ! adult walking behavior GO:0007628 36 18 0,000 0,10027758 0,13549676 ! patterning of blood vessels GO:0001569 43 18 0,000 0,10027758 0,13542186 ! heart looping GO:0001947 34 18 0,000 0,10027758 0,13534704 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,10027758 0,1352723 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,10027758 0,13519765 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,10027758 0,13512308 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,10027758 0,13504859 ! epidermis morphogenesis GO:0048730 43 18 0,000 0,10027758 0,13497418 ! glycine metabolic process GO:0006544 30 18 0,000 0,10027758 0,13489986 ! glutamine metabolic process GO:0006541 29 18 0,000 0,10027758 0,13482561 ! response to retinoic acid GO:0032526 31 18 0,000 0,10027758 0,13475145 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,10027758 0,13467737 ! DNA integration GO:0015074 32 18 0,000 0,10027758 0,13460337 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,10027758 0,13452946 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,10027758 0,13445562 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,10027758 0,13438186 ! neural crest cell migration GO:0001755 41 18 0,000 0,10027758 0,13430819 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,10027758 0,1342346 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,10027758 0,13416108 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,10027758 0,13408765 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,10027758 0,1340143 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,10027758 0,13394103 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,10027758 0,13386784 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,10027758 0,13379472 ! detection of bacterium GO:0016045 22 18 0,000 0,10027758 0,13372169 ! defense response to virus GO:0051607 43 18 0,000 0,10027758 0,13364874 ! microspike assembly GO:0030035 46 18 0,000 0,10027758 0,13357587 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,10027758 0,13350307 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 0,000 0,10027758 0,13343036 ! vitamin metabolic process GO:0006766 153 93 1,000 0,10328431 0,13735632 ! female pregnancy GO:0007565 166 94 1,000 0,10513974 0,13974777 ! carbohydrate biosynthetic process GO:0016051 158 94 1,000 0,10513974 0,13967177 ! regulation of membrane potential GO:0042391 179 94 1,000 0,10513974 0,13959587 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,10554534 0,14005826 ! positive regulation of translation GO:0045727 31 19 0,000 0,10554534 0,13998223 ! negative regulation of defense response GO:0031348 27 19 0,000 0,10554534 0,13990627 ! G1 phase of mitotic cell cycle GO:0000080 39 19 0,000 0,10554534 0,1398304 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,10554534 0,13975461 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,10554534 0,13967891 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,10554534 0,13960328 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,10554534 0,13952774 ! inositol metabolic process GO:0006020 33 19 0,000 0,10554534 0,13945228 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,10554534 0,1393769 ! memory GO:0007613 34 19 0,000 0,10554534 0,1393016 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,10554534 0,13922638 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,10554534 0,13915125 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,10554534 0,13907619 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,10554534 0,13900122 ! cerebral cortex development GO:0021987 40 19 0,000 0,10554534 0,13892633 ! pigmentation during development GO:0048066 42 19 0,000 0,10554534 0,13885152 ! response to vitamin A GO:0033189 32 19 0,000 0,10554534 0,13877678 ! heme metabolic process GO:0042168 40 19 0,000 0,10554534 0,13870213 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,10554534 0,13862756 ! regulation of endothelial cell migration GO:0010594 45 19 0,000 0,10554534 0,13855307 ! response to fungus GO:0009620 26 19 0,000 0,10554534 0,13847866 ! peptide cross-linking GO:0018149 39 19 0,000 0,10554534 0,13840433 ! protein export from nucleus GO:0006611 40 19 0,000 0,10554534 0,13833008 ! heart process GO:0003015 32 19 0,000 0,10554534 0,13825591 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,10554534 0,13818181 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,10554534 0,1381078 ! visual learning GO:0008542 38 19 0,000 0,10554534 0,13803387 ! cellular pigmentation GO:0033059 37 19 0,000 0,10554534 0,13796001 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,10554534 0,13788624 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,10554534 0,13781254 ! vitamin transport GO:0051180 31 19 0,000 0,10554534 0,13773892 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,10554534 0,13766538 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,10554534 0,13759192 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,10554534 0,13751854 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,10554534 0,13744524 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,10554534 0,13737201 ! cilium assembly GO:0042384 38 19 0,000 0,10554534 0,13729886 ! peptide hormone secretion GO:0030072 32 19 0,000 0,10554534 0,13722579 ! phospholipid biosynthetic process GO:0008654 188 95 1,000 0,10700423 0,13904858 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 1,000 0,10700423 0,13897466 ! negative regulation of multicellular organismal process GO:0051241 174 95 1,000 0,10700423 0,13890082 ! regulation of T cell activation GO:0050863 175 96 1,000 0,1088776 0,14125756 ! transcription initiation GO:0006352 171 97 1,000 0,1107597 0,14362311 ! protein secretion GO:0009306 45 20 0,000 0,1107824 0,14357634 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,1107824 0,14350021 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,1107824 0,14342417 ! skin development GO:0043588 42 20 0,000 0,1107824 0,1433482 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,1107824 0,14327231 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,1107824 0,14319651 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,1107824 0,14312078 ! response to vitamin GO:0033273 36 20 0,000 0,1107824 0,14304514 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,1107824 0,14296957 ! bile acid metabolic process GO:0008206 34 20 0,000 0,1107824 0,14289409 ! retinoid metabolic process GO:0001523 34 20 0,000 0,1107824 0,14281868 GO:0016101|diterpenoid metabolic process, ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,1107824 0,14274336 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,1107824 0,14266811 GO:0032392|DNA geometric change, ! cellular response to unfolded protein GO:0034620 35 20 0,000 0,1107824 0,14259294 GO:0030968|endoplasmic reticulum unfolded protein response, ! peptidyl-serine phosphorylation GO:0018105 44 20 0,000 0,1107824 0,14251785 ! body fluid secretion GO:0007589 33 20 0,000 0,1107824 0,14244284 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,1107824 0,14236791 ! peptide secretion GO:0002790 38 20 0,000 0,1107824 0,14229306 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,1107824 0,14221829 ! regulation of fatty acid metabolic process GO:0019217 45 20 0,000 0,1107824 0,14214359 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,1107824 0,14206898 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,1107824 0,14199444 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,1107824 0,14191998 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 0,000 0,1107824 0,1418456 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,1107824 0,1417713 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,1107824 0,14169707 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,1107824 0,14162292 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,1107824 0,14154885 ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,1107824 0,14147486 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,1107824 0,14140094 ! negative regulation of translation GO:0017148 32 20 0,000 0,1107824 0,1413271 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,1107824 0,14125334 ! leukocyte differentiation GO:0002521 232 98 1,000 0,11265034 0,14356014 ! regulation of nucleotide metabolic process GO:0006140 197 98 1,000 0,11265034 0,14348529 ! regulation of cell killing GO:0031341 46 21 0,000 0,11598894 0,14766076 ! hormone secretion GO:0046879 39 21 0,000 0,11598894 0,14758385 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,11598894 0,14750702 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,11598894 0,14743028 ! ovarian follicle development GO:0001541 39 21 0,000 0,11598894 0,14735361 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,11598894 0,14727702 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,11598894 0,14720051 ! plasma membrane fusion GO:0045026 33 21 0,000 0,11598894 0,14712409 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,11598894 0,14704774 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,11598894 0,14697147 GO:0006692|prostanoid metabolic process, ! sensory perception of pain GO:0019233 33 21 0,000 0,11598894 0,14689528 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,11598894 0,14681917 ! collagen fibril organization GO:0030199 62 21 0,000 0,11598894 0,14674313 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,11598894 0,14666718 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,11598894 0,1465913 ! collagen catabolic process GO:0030574 29 21 0,000 0,11598894 0,14651551 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,11598894 0,14643979 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,11598894 0,14636415 ! sperm-egg recognition GO:0035036 23 21 0,000 0,11598894 0,14628858 ! actin filament-based movement GO:0030048 47 21 0,000 0,11598894 0,1462131 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 0,000 0,11598894 0,14613769 ! mRNA transport GO:0051028 185 100 1,000 0,11645664 0,14665132 ! hormone metabolic process GO:0042445 171 100 1,000 0,11645664 0,14657577 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,12116515 0,15242351 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,12116515 0,15234506 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,12116515 0,1522667 ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,12116515 0,15218841 ! microtubule-based transport GO:0010970 59 22 0,000 0,12116515 0,1521102 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,12116515 0,15203208 ! cellular response to starvation GO:0009267 37 22 0,000 0,12116515 0,15195403 ! vacuolar transport GO:0007034 41 22 0,000 0,12116515 0,15187607 ! fucose metabolic process GO:0006004 44 22 0,000 0,12116515 0,15179818 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,12116515 0,15172038 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,12116515 0,15164265 ! ureteric bud development GO:0001657 50 22 0,000 0,12116515 0,15156501 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,12116515 0,15148744 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 0,12116515 0,15140995 ! cytolysis GO:0019835 27 22 0,000 0,12116515 0,15133254 ! renal system process GO:0003014 42 22 0,000 0,12116515 0,15125521 ! vasodilation GO:0042311 40 22 0,000 0,12116515 0,15117797 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,12116515 0,15110079 ! G1 phase GO:0051318 44 22 0,000 0,12116515 0,1510237 ! detection of chemical stimulus GO:0009593 42 22 0,000 0,12116515 0,15094669 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,12116515 0,15086975 ! peptidyl-serine modification GO:0018209 50 22 0,000 0,12116515 0,1507929 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,12116515 0,15071612 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,12116515 0,15063942 ! sarcomere organization GO:0045214 32 22 0,000 0,12116515 0,1505628 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,12116515 0,15048625 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,12116515 0,15040978 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,12116515 0,1503334 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,12116515 0,15025708 ! gut development GO:0048565 44 22 0,000 0,12116515 0,15018085 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,12116515 0,15010469 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 0,000 0,12116515 0,15002861 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,12631119 0,15632129 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,12631119 0,15624214 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,12631119 0,15616307 ! glycerol metabolic process GO:0006071 40 23 0,000 0,12631119 0,15608408 ! viral genome replication GO:0019079 44 23 0,000 0,12631119 0,15600517 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,12631119 0,15592634 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,12631119 0,15584759 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,12631119 0,15576892 ! regeneration GO:0031099 42 23 0,000 0,12631119 0,15569033 ! visual behavior GO:0007632 46 23 0,000 0,12631119 0,15561182 ! regulation of cell-matrix adhesion GO:0001952 81 23 0,000 0,12631119 0,15553338 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 51 23 0,000 0,12631119 0,15545503 ! response to ethanol GO:0045471 47 23 0,000 0,12631119 0,15537675 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,12631119 0,15529856 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,12631119 0,15522044 ! peroxisome organization GO:0007031 43 23 0,000 0,12631119 0,1551424 ! lysosome organization GO:0007040 47 23 0,000 0,12631119 0,15506444 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 0,12631119 0,15498656 ! vesicle targeting GO:0006903 49 23 0,000 0,12631119 0,15490875 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 0,000 0,12631119 0,15483102 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,12631119 0,15475338 GO:0060415|muscle tissue morphogenesis, ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,12631119 0,15467581 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,12631119 0,15459831 ! DNA modification GO:0006304 36 23 0,000 0,12631119 0,1545209 ! fatty acid transport GO:0015908 47 23 0,000 0,12631119 0,15444356 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,12631119 0,1543663 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,12631119 0,15428912 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,12631119 0,15421201 ! hormone transport GO:0009914 41 23 0,000 0,12631119 0,15413498 ! cell-cell recognition GO:0009988 28 23 0,000 0,12631119 0,15405803 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,12631119 0,15398115 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,12631119 0,15390436 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,12631119 0,15382763 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,13142724 0,15997845 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,13142724 0,15989878 GO:0016444|somatic cell DNA recombination, ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,13142724 0,15981919 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,13142724 0,15973968 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,13142724 0,15966024 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,13142724 0,15958089 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 0,13142724 0,15950161 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,13142724 0,15942242 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,13142724 0,1593433 GO:0042278|purine nucleoside metabolic process, ! positive regulation of cytoskeleton organization GO:0051495 52 24 0,000 0,13142724 0,15926426 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,13142724 0,1591853 GO:0051693|actin filament capping, ! regulation of viral reproduction GO:0050792 41 24 0,000 0,13142724 0,15910642 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,13142724 0,15902761 GO:0002708|positive regulation of lymphocyte mediated immunity, ! leukotriene metabolic process GO:0006691 47 24 0,000 0,13142724 0,15894888 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,13142724 0,15887024 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,13142724 0,15879167 ! membrane depolarization GO:0051899 45 24 0,000 0,13142724 0,15871317 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,13142724 0,15863476 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,13142724 0,15855642 ! platelet activation GO:0030168 41 24 0,000 0,13142724 0,15847816 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,13142724 0,15839997 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,13142724 0,15832187 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,13142724 0,15824384 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,13142724 0,15816589 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,13142724 0,15808801 ! regulation of amine transport GO:0051952 41 24 0,000 0,13142724 0,15801021 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 0,000 0,13142724 0,15793249 ! protein import into nucleus, translocation GO:0000060 51 25 0,000 0,13651348 0,16396383 ! myeloid leukocyte differentiation GO:0002573 46 25 0,000 0,13651348 0,16388325 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,13651348 0,16380276 ! leukocyte adhesion GO:0007159 55 25 0,000 0,13651348 0,16372235 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,13651348 0,16364201 ! phototransduction GO:0007602 37 25 0,000 0,13651348 0,16356176 ! keratinization GO:0031424 37 25 0,000 0,13651348 0,16348158 ! vacuole organization GO:0007033 49 25 0,000 0,13651348 0,16340148 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,13651348 0,16332146 ! chromosome condensation GO:0030261 48 25 0,000 0,13651348 0,16324152 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,13651348 0,16316166 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,13651348 0,16308187 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,13651348 0,16300216 ! immunoglobulin production GO:0002377 62 25 0,000 0,13651348 0,16292253 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,13651348 0,16284298 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,13651348 0,16276351 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,14157007 0,16871009 ! initiation of viral infection GO:0019059 60 26 0,000 0,14157007 0,16862783 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,14157007 0,16854566 ! molting cycle process GO:0022404 52 26 0,000 0,14157007 0,16846356 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,14157007 0,16838154 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,14157007 0,1682996 GO:0006479|protein amino acid methylation, ! spinal cord development GO:0021510 54 26 0,000 0,14157007 0,16821775 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,14157007 0,16813597 ! digestive system process GO:0022600 49 26 0,000 0,14157007 0,16805427 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,14157007 0,16797265 ! regulation of cellular ketone metabolic process GO:0010565 51 26 0,000 0,14157007 0,16789111 ! response to endoplasmic reticulum stress GO:0034976 46 26 0,000 0,14157007 0,16780965 ! neural crest cell development GO:0014032 59 26 0,000 0,14157007 0,16772827 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,14157007 0,16764696 ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,14157007 0,16756574 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,14157007 0,16748459 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,14157007 0,16740353 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,14157007 0,16732254 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,14157007 0,16724163 ! regulation of blood coagulation GO:0030193 46 26 0,000 0,14157007 0,1671608 ! positive regulation of nuclear division GO:0051785 41 26 0,000 0,14157007 0,16708004 GO:0045840|positive regulation of mitosis, ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,14157007 0,16699937 ! telomere organization GO:0032200 46 26 0,000 0,14157007 0,16691877 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,14157007 0,16683825 ! alditol metabolic process GO:0019400 44 26 0,000 0,14157007 0,1667578 ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,14157007 0,16667744 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,14157007 0,16659715 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,1465972 0,17242992 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,1465972 0,17234694 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,1465972 0,17226405 ! positive regulation of cell projection organization GO:0031346 66 27 0,000 0,1465972 0,17218123 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,1465972 0,17209849 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,1465972 0,17201583 ! iron ion transport GO:0006826 65 27 0,000 0,1465972 0,17193325 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,1465972 0,17185074 ! superoxide metabolic process GO:0006801 41 27 0,000 0,1465972 0,17176832 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,1465972 0,17168598 ! regulation of endothelial cell proliferation GO:0001936 60 27 0,000 0,1465972 0,17160371 ! mitochondrial membrane organization GO:0007006 60 27 0,000 0,1465972 0,17152153 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,1465972 0,17143942 ! response to starvation GO:0042594 47 27 0,000 0,1465972 0,17135739 ! response to toxin GO:0009636 49 27 0,000 0,1465972 0,17127544 ! cellular response to oxidative stress GO:0034599 43 27 0,000 0,1465972 0,17119357 ! cellular response to nutrient levels GO:0031669 45 27 0,000 0,1465972 0,17111178 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,1465972 0,17103006 ! leukocyte proliferation GO:0070661 59 27 0,000 0,1465972 0,17094843 GO:0032943|mononuclear cell proliferation, ! vesicle docking GO:0048278 55 28 0,000 0,15159502 0,1766921 ! circadian rhythm GO:0007623 56 28 0,000 0,15159502 0,17660784 ! dendrite development GO:0016358 67 28 0,000 0,15159502 0,17652366 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,15159502 0,17643956 ! sperm motility GO:0030317 37 28 0,000 0,15159502 0,17635554 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,15159502 0,1762716 ! base-excision repair GO:0006284 41 28 0,000 0,15159502 0,17618775 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,15159502 0,17610397 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,15159502 0,17602027 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,15159502 0,17593665 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,15159502 0,17585311 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,15159502 0,17576964 ! lipid oxidation GO:0034440 48 28 0,000 0,15159502 0,17568626 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,15159502 0,17560296 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,15159502 0,17551973 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 0,000 0,15656372 0,18118672 ! translational initiation GO:0006413 66 29 0,000 0,15656372 0,18110093 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,15656372 0,18101522 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,15656372 0,1809296 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! ER-nuclear signaling pathway GO:0006984 52 29 0,000 0,15656372 0,18084405 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,15656372 0,18075859 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,15656372 0,1806732 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 0,000 0,15656372 0,1805879 ! synaptogenesis GO:0007416 46 29 0,000 0,15656372 0,18050267 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,15656372 0,18041753 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,15656372 0,18033247 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,15656372 0,18024749 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,16150346 0,18584689 ! phenol metabolic process GO:0018958 56 30 0,000 0,16150346 0,18575939 ! negative regulation of protein complex assembly GO:0031333 68 30 0,000 0,16150346 0,18567197 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,16150346 0,18558464 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,16150346 0,18549739 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,16150346 0,18541022 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,16150346 0,18532313 ! acute-phase response GO:0006953 50 30 0,000 0,16150346 0,18523612 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,16150346 0,1851492 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,16150346 0,18506236 ! myofibril assembly GO:0030239 50 30 0,000 0,16150346 0,18497559 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 72 30 0,000 0,16150346 0,18488891 ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,16150346 0,18480232 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,16150346 0,1847158 ! positive regulation of multicellular organism growth GO:0040018 55 30 0,000 0,16150346 0,18462936 ! phospholipid transport GO:0015914 65 30 0,000 0,16150346 0,184543 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,16150346 0,18445673 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,16150346 0,18437053 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,16150346 0,18428442 ! regulation of coagulation GO:0050818 52 30 0,000 0,16150346 0,18419839 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,1664144 0,18971086 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,1664144 0,18962238 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,1664144 0,18953398 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,1664144 0,18944566 ! regulation of innate immune response GO:0045088 57 31 0,000 0,1664144 0,18935742 ! ovulation cycle process GO:0022602 55 31 0,000 0,1664144 0,18926926 ! peptide transport GO:0015833 60 31 0,000 0,1664144 0,18918119 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,1664144 0,1890932 ! detection of light stimulus GO:0009583 44 31 0,000 0,1664144 0,18900529 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 0,000 0,1664144 0,18891746 ! natural killer cell activation GO:0030101 50 31 0,000 0,1664144 0,18882972 ! cofactor catabolic process GO:0051187 54 31 0,000 0,1664144 0,18874205 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,1664144 0,18865447 ! eye morphogenesis GO:0048592 65 31 0,000 0,1664144 0,18856697 ! response to heat GO:0009408 54 31 0,000 0,1664144 0,18847955 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,1664144 0,18839221 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,17129672 0,1938295 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,17129672 0,19373976 ! collagen metabolic process GO:0032963 49 32 0,000 0,17129672 0,19365011 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,17129672 0,19356054 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,17129672 0,19347105 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,17129672 0,19338165 ! muscle cell development GO:0055001 52 32 0,000 0,17129672 0,19329233 ! mesoderm formation GO:0001707 73 32 0,000 0,17129672 0,19320309 ! ovulation cycle GO:0042698 57 32 0,000 0,17129672 0,19311393 ! BMP signaling pathway GO:0030509 71 32 0,000 0,17129672 0,19302486 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,17129672 0,19293586 ! gene silencing GO:0016458 71 32 0,000 0,17129672 0,19284695 ! regulation of pH GO:0006885 56 33 0,000 0,17615058 0,19822011 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,17615058 0,19812885 ! pigment biosynthetic process GO:0046148 73 33 0,000 0,17615058 0,19803767 ! positive regulation of gene-specific transcription GO:0043193 70 33 0,000 0,17615058 0,19794658 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,17615058 0,19785557 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,17615058 0,19776464 ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,17615058 0,1976738 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,17615058 0,19758304 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,17615058 0,19749237 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,18097615 0,20280951 ! glial cell differentiation GO:0010001 67 34 0,000 0,18097615 0,20271652 ! post-embryonic development GO:0009791 76 34 0,000 0,18097615 0,20262361 ! cholesterol transport GO:0030301 62 34 0,000 0,18097615 0,20253079 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,18097615 0,20243806 ! spliceosome assembly GO:0000245 75 34 0,000 0,18097615 0,20234541 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,18097615 0,20225285 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,18097615 0,20216037 ! formation of primary germ layer GO:0001704 76 34 0,000 0,18097615 0,20206797 ! cell fate specification GO:0001708 56 34 0,000 0,18097615 0,20197566 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,18097615 0,20188344 ! adult locomotory behavior GO:0008344 62 34 0,000 0,18097615 0,20179129 ! DNA damage checkpoint GO:0000077 78 35 0,000 0,18577358 0,20704601 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,18577358 0,2069516 ! negative regulation of secretion GO:0051048 68 35 0,000 0,18577358 0,20685728 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,18577358 0,20676303 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,18577358 0,20666888 ! membrane docking GO:0022406 69 35 0,000 0,18577358 0,20657481 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,18577358 0,20648083 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,18577358 0,20638693 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,18577358 0,20629312 ! ceramide metabolic process GO:0006672 72 35 0,000 0,18577358 0,20619939 ! sterol transport GO:0015918 63 35 0,000 0,18577358 0,20610575 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,18577358 0,20601219 ! placenta development GO:0001890 53 35 0,000 0,18577358 0,20591872 ! vesicle localization GO:0051648 70 35 0,000 0,18577358 0,20582533 ! mitotic sister chromatid segregation GO:0000070 63 36 0,000 0,19054305 0,21101391 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,19054305 0,21091829 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,19054305 0,21082277 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,19054305 0,21072733 ! protein targeting to membrane GO:0006612 75 36 0,000 0,19054305 0,21063198 ! regulation of proteolysis GO:0030162 77 36 0,000 0,19054305 0,21053671 ! negative regulation of hydrolase activity GO:0051346 66 36 0,000 0,19054305 0,21044154 ! aerobic respiration GO:0009060 56 36 0,000 0,19054305 0,21034644 ! embryonic organ development GO:0048568 67 36 0,000 0,19054305 0,21025143 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,19054305 0,21015651 ! regulation of smooth muscle cell proliferation GO:0048660 64 37 0,000 0,19528472 0,21528906 ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,19528472 0,21519195 ! sister chromatid segregation GO:0000819 65 37 0,000 0,19528472 0,21509493 ! odontogenesis GO:0042476 74 37 0,000 0,19528472 0,214998 ! actomyosin structure organization GO:0031032 68 37 0,000 0,19528472 0,21490115 ! tissue remodeling GO:0048771 78 37 0,000 0,19528472 0,2148044 ! regulation of microtubule-based process GO:0032886 86 37 0,000 0,19528472 0,21470772 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,19999874 0,21979169 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,19999874 0,21969286 ! organic anion transport GO:0015711 82 38 0,000 0,19999874 0,21959412 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,19999874 0,21949547 ! DNA integrity checkpoint GO:0031570 82 38 0,000 0,19999874 0,21939691 ! spermatid development GO:0007286 69 38 0,000 0,19999874 0,21929844 ! glycogen metabolic process GO:0005977 63 38 0,000 0,19999874 0,21920005 ! pigment metabolic process GO:0042440 87 38 0,000 0,19999874 0,21910176 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,20468528 0,22413543 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,20468528 0,22403501 ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,20468528 0,22393468 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,20468528 0,22383444 ! erythrocyte homeostasis GO:0034101 75 39 0,000 0,20468528 0,22373429 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,20468528 0,22363423 ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,20468528 0,22353426 ! glucan metabolic process GO:0044042 64 39 0,000 0,20468528 0,22343438 GO:0006073|cellular glucan metabolic process, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,20934449 0,22841831 GO:0006956|complement activation, ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,20934449 0,22831634 ! mismatch repair GO:0006298 58 40 0,000 0,20934449 0,22821446 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,20934449 0,22811267 ! RNA export from nucleus GO:0006405 61 41 0,000 0,21397655 0,23305604 ! mRNA catabolic process GO:0006402 79 41 0,000 0,21397655 0,23295218 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,21397655 0,23284842 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,21397655 0,23274475 ! gliogenesis GO:0042063 91 41 0,000 0,21397655 0,23264117 ! feeding behavior GO:0007631 69 41 0,000 0,21397655 0,23253768 ! multicellular organismal metabolic process GO:0044236 64 41 0,000 0,21397655 0,23243428 ! monovalent inorganic cation homeostasis GO:0055067 72 41 0,000 0,21397655 0,23233098 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,21397655 0,23222777 GO:0015986|ATP synthesis coupled proton transport, ! spermatid differentiation GO:0048515 73 41 0,000 0,21397655 0,23212464 ! RNA modification GO:0009451 64 41 0,000 0,21397655 0,23202162 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,21858159 0,23690986 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,21858159 0,2368048 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,21858159 0,23669983 ! regulation of protein secretion GO:0050708 77 42 0,000 0,21858159 0,23659496 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,21858159 0,23649018 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,22315978 0,24133659 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,22315978 0,2412298 ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,22315978 0,24112311 ! striated muscle cell differentiation GO:0051146 91 43 0,000 0,22315978 0,24101651 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,22315978 0,24091001 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,22315978 0,2408036 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,22315978 0,24069728 ! ion transmembrane transport GO:0034220 79 43 0,000 0,22315978 0,24059106 ! regulation of myeloid cell differentiation GO:0045637 105 43 0,000 0,22315978 0,24048494 ! response to reactive oxygen species GO:0000302 75 44 0,000 0,22771128 0,2452816 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,22771128 0,2451735 ! energy reserve metabolic process GO:0006112 76 44 0,000 0,22771128 0,24506549 ! negative regulation of protein complex disassembly GO:0043242 113 44 0,000 0,22771128 0,24495758 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 0,000 0,22771128 0,24484976 ! striated muscle contraction GO:0006941 85 44 0,000 0,22771128 0,24474204 ! phagocytosis GO:0006909 105 44 0,000 0,22771128 0,24463442 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,22771128 0,24452688 ! branching morphogenesis of a tube GO:0048754 102 45 0,000 0,23223624 0,24927642 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,23223624 0,24916695 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! keratinocyte differentiation GO:0030216 81 45 0,000 0,23223624 0,24905757 ! biopolymer methylation GO:0043414 91 45 0,000 0,23223624 0,24894828 ! B cell differentiation GO:0030183 124 45 0,000 0,23223624 0,2488391 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,23223624 0,24873 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,23223624 0,24862101 ! polyol metabolic process GO:0019751 77 45 0,000 0,23223624 0,24851211 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,23673481 0,25321504 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,23673481 0,25310422 ! glycolysis GO:0006096 71 46 0,000 0,23673481 0,25299351 ! negative regulation of cell migration GO:0030336 122 46 0,000 0,23673481 0,25288288 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,23673481 0,25277236 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,23673481 0,25266193 ! cell growth GO:0016049 90 46 0,000 0,23673481 0,25255159 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,24120716 0,25721042 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,24565342 0,26183739 ! mitochondrial transport GO:0006839 94 48 0,000 0,24565342 0,2617232 ! regulation of JAK-STAT cascade GO:0046425 76 48 0,000 0,24565342 0,26160911 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 0,000 0,24565342 0,26149512 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,24565342 0,26138123 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,24565342 0,26126743 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,24565342 0,26115374 ! methylation GO:0032259 97 48 0,000 0,24565342 0,26104015 ! response to calcium ion GO:0051592 94 49 0,000 0,25007375 0,26562181 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,25007375 0,26550637 ! JNK cascade GO:0007254 106 49 0,000 0,25007375 0,26539104 ! regulation of ion transport GO:0043269 86 50 0,000 0,2544683 0,2699375 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,2544683 0,26982034 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,2544683 0,26970328 GO:0019724|B cell mediated immunity, ! regulation of gene expression, epigenetic GO:0040029 116 50 0,000 0,2544683 0,26958632 ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,2544683 0,26946947 ! epidermal cell differentiation GO:0009913 87 50 0,000 0,2544683 0,26935271 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,2544683 0,26923606 ! regulation of cell projection organization GO:0031344 135 51 0,000 0,25883723 0,27373997 ! viral infectious cycle GO:0019058 104 51 0,000 0,25883723 0,27362152 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,25883723 0,27350318 ! response to temperature stimulus GO:0009266 84 51 0,000 0,25883723 0,27338493 ! regulation of protein complex disassembly GO:0043244 127 52 0,000 0,26318067 0,27785237 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,26318067 0,27773234 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,26318067 0,27761242 ! excretion GO:0007588 87 52 0,000 0,26318067 0,27749261 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,26318067 0,2773729 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,26318067 0,27725329 ! morphogenesis of a branching structure GO:0001763 116 52 0,000 0,26318067 0,27713378 ! respiratory electron transport chain GO:0022904 83 53 0,000 0,26749878 0,28155947 ! chromatin remodeling GO:0006338 122 53 0,000 0,26749878 0,28143821 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,26749878 0,28131706 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,26749878 0,28119601 ! vesicle organization GO:0016050 127 53 0,000 0,26749878 0,28107506 ! regulation of neuron apoptosis GO:0043523 117 53 0,000 0,26749878 0,28095422 ! regulation of translational initiation GO:0006446 87 54 0,000 0,27179171 0,28534041 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,27179171 0,28521784 ! neuromuscular process GO:0050905 107 54 0,000 0,27179171 0,28509538 ! membrane fusion GO:0006944 122 54 0,000 0,27179171 0,28497302 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,27179171 0,28485077 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,27179171 0,28472862 ! regulation of cell shape GO:0008360 142 54 0,000 0,27179171 0,28460658 ! RNA catabolic process GO:0006401 103 55 0,000 0,27605959 0,28895184 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,27605959 0,28882809 ! regulation of multicellular organism growth GO:0040014 90 55 0,000 0,27605959 0,28870445 ! regulation of protein polymerization GO:0032271 117 55 0,000 0,27605959 0,28858091 ! negative regulation of cell motion GO:0051271 142 55 0,000 0,27605959 0,28845748 ! negative regulation of cytoskeleton organization GO:0051494 139 56 0,000 0,28030259 0,29276581 ! glucose catabolic process GO:0006007 88 56 0,000 0,28030259 0,29264069 ! RNA elongation GO:0006354 90 56 0,000 0,28030259 0,29251569 ! regulation of actin filament length GO:0030832 118 58 0,000 0,28871447 0,30116544 ! cellular polysaccharide metabolic process GO:0044264 93 58 0,000 0,28871447 0,3010369 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,28871447 0,30090847 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,28871447 0,30078015 ! gastrulation GO:0007369 122 58 0,000 0,28871447 0,30065194 ! positive regulation of organelle organization GO:0010638 108 58 0,000 0,28871447 0,30052384 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,28871447 0,30039585 ! nuclear export GO:0051168 110 59 0,000 0,29288365 0,30460398 ! establishment of organelle localization GO:0051656 122 59 0,000 0,29288365 0,30447436 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,2970285 0,30865191 ! regulation of endocytosis GO:0030100 104 60 0,000 0,2970285 0,30852068 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,2970285 0,30838956 ! adult behavior GO:0030534 104 60 0,000 0,2970285 0,30825855 ! regulation of cellular component size GO:0032535 125 61 0,000 0,30114918 0,31240231 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,30114918 0,31226971 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,30114918 0,31213723 ! proton transport GO:0015992 117 61 0,000 0,30114918 0,31200485 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,30524582 0,3161151 ! tRNA processing GO:0008033 102 62 0,000 0,30524582 0,31598116 ! regulation of protein complex assembly GO:0043254 132 63 0,000 0,30931855 0,32006151 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,30931855 0,31992601 ! hydrogen transport GO:0006818 121 64 0,000 0,31336753 0,32397667 ! integrin-mediated signaling pathway GO:0007229 160 64 0,000 0,31336753 0,32383963 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,31739288 0,32786081 ! lymphocyte mediated immunity GO:0002449 122 65 0,000 0,31739288 0,32772224 ! multicellular organism reproduction GO:0032504 123 65 0,000 0,31739288 0,32758378 GO:0048609|reproductive process in a multicellular organism, ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,31739288 0,32744545 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,32139475 0,3314341 ! regulation of lipid metabolic process GO:0019216 132 66 0,000 0,32139475 0,33129425 ! chromosome segregation GO:0007059 127 67 0,000 0,32537327 0,33525386 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,32537327 0,33511252 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,32537327 0,3349713 ! secondary metabolic process GO:0019748 125 67 0,000 0,32537327 0,3348302 ! regulation of cellular response to stress GO:0080135 142 68 0,000 0,32932858 0,33875777 ! hexose catabolic process GO:0019320 113 68 0,000 0,32932858 0,3386152 ! negative regulation of ligase activity GO:0051352 116 68 0,000 0,32932858 0,33847274 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,32932858 0,33833041 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,3332608 0,34222621 ! single fertilization GO:0007338 83 69 0,000 0,3332608 0,34208241 ! cell redox homeostasis GO:0045454 114 70 0,000 0,33717008 0,34594982 ! activation of immune response GO:0002253 120 70 0,000 0,33717008 0,34580458 ! protein maturation by peptide bond cleavage GO:0051605 118 70 0,000 0,33717008 0,34565947 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,34105655 0,34949713 ! B cell activation GO:0042113 179 72 0,000 0,34492034 0,35330834 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,34492034 0,35316027 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,34492034 0,35301232 ! regulation of MAPKKK cascade GO:0043408 157 72 0,000 0,34492034 0,35286449 ! humoral immune response GO:0006959 115 73 0,000 0,34876159 0,35664485 ! regulation of immune effector process GO:0002697 156 73 0,000 0,34876159 0,35649563 ! acute inflammatory response GO:0002526 118 74 0,000 0,35258041 0,36024841 ! amino acid transport GO:0006865 148 74 0,000 0,35258041 0,36009781 ! transition metal ion transport GO:0000041 143 75 0,000 0,35637695 0,36382319 ! leukocyte mediated immunity GO:0002443 136 75 0,000 0,35637695 0,36367122 ! rhythmic process GO:0048511 142 75 0,000 0,35637695 0,36351937 ! regulation of actin cytoskeleton organization GO:0032956 167 76 0,000 0,36015134 0,36721607 ! amine catabolic process GO:0009310 136 77 0,000 0,36390369 0,37088724 ! neurotransmitter transport GO:0006836 142 77 0,000 0,36390369 0,37073258 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,36390369 0,37057804 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,36390369 0,37042363 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,36763415 0,37406506 ! antigen processing and presentation GO:0019882 117 78 0,000 0,36763415 0,37390933 ! fertilization GO:0009566 99 78 0,000 0,36763415 0,37375373 ! blood coagulation GO:0007596 151 79 0,000 0,37134283 0,37736711 GO:0050817|coagulation, ! regulation of actin filament-based process GO:0032970 170 79 0,000 0,37134283 0,3772102 ! regulation of synaptic transmission GO:0050804 159 79 0,000 0,37134283 0,37705342 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 0,000 0,37502986 0,38063895 ! negative regulation of organelle organization GO:0010639 181 80 0,000 0,37502986 0,38048088 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 0,000 0,37869538 0,38404018 ! protein import into nucleus GO:0006606 174 82 0,000 0,38233949 0,38757485 ! exocytosis GO:0006887 153 83 0,000 0,38596234 0,39108503 ! nuclear import GO:0051170 177 83 0,000 0,38596234 0,39092289 ! response to metal ion GO:0010038 158 84 0,000 0,38956404 0,39440736 ! digestion GO:0007586 130 84 0,000 0,38956404 0,39424397 ! hemostasis GO:0007599 165 85 0,000 0,39314471 0,39770291 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,39314471 0,3975383 ! regulation of transmission of nerve impulse GO:0051969 167 85 0,000 0,39314471 0,39737382 ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,40024347 0,40438164 ! alcohol catabolic process GO:0046164 142 87 0,000 0,40024347 0,40421447 ! nucleosome assembly GO:0006334 126 87 0,000 0,40024347 0,40404744 ! cellular respiration GO:0045333 143 88 0,000 0,4037618 0,40743085 ! amine biosynthetic process GO:0009309 146 88 0,000 0,4037618 0,40726263 ! sensory perception of smell GO:0007608 117 88 0,000 0,4037618 0,40709454 ! chromatin assembly GO:0031497 128 88 0,000 0,4037618 0,4069266 ! one-carbon metabolic process GO:0006730 167 88 0,000 0,4037618 0,4067588 ! cellular defense response GO:0006968 123 89 0,000 0,40725959 0,41011343 ! protein localization in nucleus GO:0034504 192 89 0,000 0,40725959 0,40994445 ! regulation of neurological system process GO:0031644 175 89 0,000 0,40725959 0,40977561 ! response to inorganic substance GO:0010035 173 90 0,000 0,41073695 0,41310431 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,41073695 0,41293431 ! response to unfolded protein GO:0006986 139 90 0,000 0,41073695 0,41276445 ! defense response to bacterium GO:0042742 112 91 0,000 0,41419402 0,41606743 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,41763089 0,41934742 ! regulation of cell morphogenesis GO:0022604 243 93 0,000 0,42104771 0,42260458 ! amine transport GO:0015837 181 93 0,000 0,42104771 0,42243102 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,42444457 0,42566423 ! sterol metabolic process GO:0016125 166 94 0,000 0,42444457 0,42548957 ! nucleosome organization GO:0034728 143 95 0,000 0,42782159 0,42869899 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,42782159 0,42852322 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,42782159 0,4283476 ! response to protein stimulus GO:0051789 158 96 0,000 0,4311789 0,43153218 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,4345166 0,43469453 ! positive regulation of immune response GO:0050778 175 100 0,000 0,4444132 0,4444132