pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6682-VanDeVijver-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/vantveer-oligo_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! epidermal growth factor receptor signaling pathway GO:0007173 18 18 4,000 9,15E-09 1,686E-05 ! positive regulation of MAP kinase activity GO:0043406 50 49 5,000 4,965E-08 4,576E-05 ! regulation of intracellular protein transport GO:0033157 25 25 4,000 5,555E-08 3,413E-05 ! regulation of nucleocytoplasmic transport GO:0046822 27 27 4,000 8,389E-08 3,865E-05 ! protein amino acid autophosphorylation GO:0046777 28 28 4,000 1,018E-07 3,753E-05 ! regulation of intracellular transport GO:0032386 31 31 4,000 1,744E-07 5,358E-05 ! regulation of MAP kinase activity GO:0043405 67 66 5,000 3,065E-07 8,071E-05 ! ER overload response GO:0006983 6 6 2,000 1,484E-06 3,418E-04 ! positive regulation of protein kinase activity GO:0045860 89 86 5,000 1,494E-06 3,058E-04 ! regulation of catabolic process GO:0009894 48 47 4,000 1,5E-06 2,765E-04 ! positive regulation of transferase activity GO:0051347 91 88 5,000 1,711E-06 2,867E-04 GO:0033674|positive regulation of kinase activity, ! regulation of protein transport GO:0051223 53 53 4,000 2,756E-06 4,232E-04 GO:0070201|regulation of establishment of protein localization, ! regulation of protein localization GO:0032880 58 57 4,000 3,972E-06 5,631E-04 ! release of cytochrome c from mitochondria GO:0001836 9 8 2,000 4,129E-06 5,436E-04 ! apoptotic mitochondrial changes GO:0008637 11 10 2,000 8,797E-06 1,081E-03 ! Ras protein signal transduction GO:0007265 69 67 4,000 8,887E-06 1,024E-03 ! positive regulation of transport GO:0051050 71 70 4,000 1,104E-05 1,196E-03 ! positive regulation of nucleocytoplasmic transport GO:0046824 11 11 2,000 1,206E-05 1,235E-03 GO:0032388|positive regulation of intracellular transport, ! positive regulation of nitric oxide biosynthetic process GO:0045429 11 11 2,000 1,206E-05 1,17E-03 ! DNA damage response, signal transduction GO:0042770 37 37 3,000 1,756E-05 1,618E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 13 13 2,000 2,078E-05 1,824E-03 ! receptor metabolic process GO:0043112 14 13 2,000 2,078E-05 1,741E-03 ! response to endoplasmic reticulum stress GO:0034976 13 13 2,000 2,078E-05 1,665E-03 ! protein tetramerization GO:0051262 13 13 2,000 2,078E-05 1,596E-03 ! activation of MAPK activity GO:0000187 39 39 3,000 2,174E-05 1,602E-03 ! positive regulation of cell motion GO:0051272 39 39 3,000 2,174E-05 1,541E-03 ! positive regulation of epithelial cell proliferation GO:0050679 14 14 2,000 2,637E-05 1,8E-03 ! regulation of cellular localization GO:0060341 86 85 4,000 2,858E-05 1,881E-03 ! insulin receptor signaling pathway GO:0008286 17 15 2,000 3,287E-05 2,089E-03 ! ER-nuclear signaling pathway GO:0006984 15 15 2,000 3,287E-05 2,019E-03 ! positive regulation of catabolic process GO:0009896 16 16 2,000 4,033E-05 2,398E-03 ! cellular response to hormone stimulus GO:0032870 48 46 3,000 4,222E-05 2,431E-03 ! negative regulation of cell development GO:0010721 18 17 2,000 4,883E-05 2,727E-03 GO:0050768|negative regulation of neurogenesis, ! cell cycle arrest GO:0007050 49 49 3,000 5,432E-05 2,944E-03 ! regulation of cellular catabolic process GO:0031329 18 18 2,000 5,842E-05 3,076E-03 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 18 18 2,000 5,842E-05 2,991E-03 ! negative regulation of transport GO:0051051 51 50 3,000 5,886E-05 2,932E-03 ! DNA damage checkpoint GO:0000077 19 19 2,000 6,917E-05 3,355E-03 ! DNA integrity checkpoint GO:0031570 21 21 2,000 9,439E-05 4,46E-03 ! negative regulation of hydrolase activity GO:0051346 21 21 2,000 9,439E-05 4,349E-03 ! cellular response to insulin stimulus GO:0032869 23 21 2,000 9,439E-05 4,243E-03 ! negative regulation of protein transport GO:0051224 21 21 2,000 9,439E-05 4,142E-03 ! peptidyl-amino acid modification GO:0018193 61 59 3,000 1,132E-04 4,852E-03 ! positive regulation of growth GO:0045927 23 23 2,000 1,249E-04 5,234E-03 ! cell projection assembly GO:0030031 25 23 2,000 1,249E-04 5,117E-03 ! axonogenesis GO:0007409 66 62 3,000 1,375E-04 5,509E-03 ! glucose homeostasis GO:0042593 24 24 2,000 1,424E-04 5,583E-03 GO:0033500|carbohydrate homeostasis, ! regulation of gene-specific transcription GO:0032583 25 25 2,000 1,613E-04 6,194E-03 ! induction of apoptosis by intracellular signals GO:0008629 26 26 2,000 1,818E-04 6,839E-03 ! response to insulin stimulus GO:0032868 28 26 2,000 1,818E-04 6,702E-03 ! positive regulation of glucose metabolic process GO:0010907 5 5 1,000 1,823E-04 6,589E-03 ! metencephalon development GO:0022037 5 5 1,000 1,823E-04 6,462E-03 ! regulation of epidermal growth factor receptor activity GO:0007176 5 5 1,000 1,823E-04 6,34E-03 GO:0010469|regulation of receptor activity, ! dopamine receptor signaling pathway GO:0007212 5 5 1,000 1,823E-04 6,223E-03 ! regulation of phospholipase A2 activity GO:0032429 5 5 1,000 1,823E-04 6,11E-03 ! substrate-bound cell migration, cell extension GO:0006930 5 5 1,000 1,823E-04 6,001E-03 ! receptor clustering GO:0043113 5 5 1,000 1,823E-04 5,895E-03 ! actin cytoskeleton reorganization GO:0031532 5 5 1,000 1,823E-04 5,794E-03 ! protein heterooligomerization GO:0051291 5 5 1,000 1,823E-04 5,696E-03 ! T cell lineage commitment GO:0002360 5 5 1,000 1,823E-04 5,601E-03 ! peptidyl-lysine modification GO:0018205 5 5 1,000 1,823E-04 5,509E-03 ! negative regulation of neuroblast proliferation GO:0007406 5 5 1,000 1,823E-04 5,42E-03 ! ATP catabolic process GO:0006200 5 5 1,000 1,823E-04 5,334E-03 ! cell morphogenesis involved in neuron differentiation GO:0048667 72 67 3,000 1,861E-04 5,358E-03 GO:0048812|neuron projection morphogenesis, GO:0048858|cell projection morphogenesis, ! cell part morphogenesis GO:0032990 75 70 3,000 2,206E-04 6,254E-03 ! positive regulation of cell cycle GO:0045787 29 29 2,000 2,533E-04 7,073E-03 ! regulation of epithelial cell proliferation GO:0050678 29 29 2,000 2,533E-04 6,967E-03 ! positive regulation of protein transport GO:0051222 29 29 2,000 2,533E-04 6,865E-03 ! response to UV GO:0009411 29 29 2,000 2,533E-04 6,765E-03 ! axon extension GO:0048675 7 6 1,000 2,728E-04 7,181E-03 ! N-terminal protein amino acid modification GO:0031365 6 6 1,000 2,728E-04 7,08E-03 GO:0018409|peptide or protein amino-terminal blocking, ! virus-host interaction GO:0019048 6 6 1,000 2,728E-04 6,982E-03 ! positive regulation of transcription factor import into nucleus GO:0042993 6 6 1,000 2,728E-04 6,886E-03 ! positive regulation of cell growth GO:0030307 6 6 1,000 2,728E-04 6,793E-03 ! ribonucleoside triphosphate catabolic process GO:0009203 6 6 1,000 2,728E-04 6,703E-03 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! nerve growth factor receptor signaling pathway GO:0048011 6 6 1,000 2,728E-04 6,614E-03 ! negative regulation of T cell proliferation GO:0042130 6 6 1,000 2,728E-04 6,528E-03 GO:0070667|negative regulation of mast cell proliferation, ! peptidyl-serine phosphorylation GO:0018105 6 6 1,000 2,728E-04 6,445E-03 ! G1 DNA damage checkpoint GO:0031571 6 6 1,000 2,728E-04 6,363E-03 ! negative regulation of axonogenesis GO:0050771 7 6 1,000 2,728E-04 6,284E-03 ! regulation of T cell differentiation in the thymus GO:0033081 6 6 1,000 2,728E-04 6,206E-03 ! phosphoinositide 3-kinase cascade GO:0014065 6 6 1,000 2,728E-04 6,13E-03 ! regulation of cellular carbohydrate catabolic process GO:0043471 6 6 1,000 2,728E-04 6,057E-03 GO:0043470|regulation of carbohydrate catabolic process, GO:0006110|regulation of glycolysis, ! regulation of embryonic development GO:0045995 6 6 1,000 2,728E-04 5,984E-03 ! localization within membrane GO:0051668 6 6 1,000 2,728E-04 5,914E-03 ! regulation of DNA replication GO:0006275 32 31 2,000 3,097E-04 6,638E-03 ! cell morphogenesis involved in differentiation GO:0000904 82 77 3,000 3,187E-04 6,752E-03 ! regulation of cell motion GO:0051270 79 79 3,000 3,517E-04 7,367E-03 ! neuron projection development GO:0031175 85 80 3,000 3,691E-04 7,644E-03 ! negative regulation of cell projection organization GO:0031345 8 7 1,000 3,808E-04 7,798E-03 ! positive regulation of cellular catabolic process GO:0031331 7 7 1,000 3,808E-04 7,713E-03 ! keratinocyte proliferation GO:0043616 7 7 1,000 3,808E-04 7,629E-03 ! regulation of mRNA processing GO:0050684 7 7 1,000 3,808E-04 7,547E-03 ! negative regulation of lymphocyte proliferation GO:0050672 7 7 1,000 3,808E-04 7,467E-03 GO:0032945|negative regulation of mononuclear cell proliferation, GO:0070664|negative regulation of leukocyte proliferation, ! response to X-ray GO:0010165 7 7 1,000 3,808E-04 7,388E-03 ! regulation of intracellular pH GO:0051453 7 7 1,000 3,808E-04 7,311E-03 ! positive regulation of carbohydrate metabolic process GO:0045913 7 7 1,000 3,808E-04 7,236E-03 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! purine nucleoside triphosphate catabolic process GO:0009146 7 7 1,000 3,808E-04 7,162E-03 ! purine ribonucleotide catabolic process GO:0009154 7 7 1,000 3,808E-04 7,09E-03 ! response to gamma radiation GO:0010332 8 7 1,000 3,808E-04 7,019E-03 ! negative regulation of T cell activation GO:0050868 7 7 1,000 3,808E-04 6,949E-03 ! MAPKKK cascade GO:0000165 82 81 3,000 3,871E-04 6,995E-03 ! regulation of protein catabolic process GO:0042176 35 34 2,000 4,087E-04 7,314E-03 ! response to peptide hormone stimulus GO:0043434 36 34 2,000 4,087E-04 7,243E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 35 35 2,000 4,457E-04 7,824E-03 ! positive regulation of cell migration GO:0030335 36 36 2,000 4,848E-04 8,43E-03 ! ribonucleotide catabolic process GO:0009261 8 8 1,000 5,064E-04 8,722E-03 ! sex determination GO:0007530 8 8 1,000 5,064E-04 8,641E-03 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 8 8 1,000 5,064E-04 8,562E-03 ! nucleoside triphosphate catabolic process GO:0009143 8 8 1,000 5,064E-04 8,484E-03 ! peptidyl-serine modification GO:0018209 8 8 1,000 5,064E-04 8,408E-03 ! regulation of generation of precursor metabolites and energy GO:0043467 8 8 1,000 5,064E-04 8,333E-03 ! cytoplasmic sequestering of protein GO:0051220 8 8 1,000 5,064E-04 8,259E-03 ! heart development GO:0007507 90 87 3,000 5,086E-04 8,223E-03 ! regulation of transcription factor activity GO:0051090 38 37 2,000 5,261E-04 8,431E-03 GO:0090046|regulation of transcription regulator activity, ! protein oligomerization GO:0051259 39 39 2,000 6,151E-04 9,773E-03 ! positive regulation of cell size GO:0045793 9 9 1,000 6,493E-04 0,01022802 ! regulation of nitric-oxide synthase activity GO:0050999 9 9 1,000 6,493E-04 0,01014134 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 9 9 1,000 6,493E-04 0,01005612 ! substrate-bound cell migration GO:0006929 9 9 1,000 6,493E-04 9,972E-03 ! negative regulation of caspase activity GO:0043154 9 9 1,000 6,493E-04 9,89E-03 ! positive regulation of protein import into nucleus GO:0042307 9 9 1,000 6,493E-04 9,809E-03 ! regulation of cellular pH GO:0030641 9 9 1,000 6,493E-04 9,729E-03 ! histone acetylation GO:0016573 9 9 1,000 6,493E-04 9,651E-03 ! cell cycle checkpoint GO:0000075 42 41 2,000 7,133E-04 0,01051676 ! regulation of caspase activity GO:0043281 41 41 2,000 7,133E-04 0,01043329 ! regulation of cell growth GO:0001558 97 96 3,000 7,387E-04 0,01071978 ! regulation of endopeptidase activity GO:0052548 42 42 2,000 7,659E-04 0,01102783 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 10 10 1,000 8,094E-04 0,0115643 ! regulation of glucose metabolic process GO:0010906 10 10 1,000 8,094E-04 0,01147534 ! negative regulation of nucleocytoplasmic transport GO:0046823 10 10 1,000 8,094E-04 0,01138774 ! purine ribonucleoside metabolic process GO:0046128 10 10 1,000 8,094E-04 0,01130147 GO:0042278|purine nucleoside metabolic process, ! neuromuscular junction development GO:0007528 10 10 1,000 8,094E-04 0,0112165 ! positive regulation of neuron apoptosis GO:0043525 10 10 1,000 8,094E-04 0,01113279 ! protein stabilization GO:0050821 10 10 1,000 8,094E-04 0,01105033 ! mitochondrion organization GO:0007005 44 43 2,000 8,209E-04 0,01112483 ! response to hormone stimulus GO:0009725 102 100 3,000 8,615E-04 0,01158881 ! regulation of DNA binding GO:0051101 47 45 2,000 9,384E-04 0,01253235 ! positive regulation of hormone secretion GO:0046887 11 11 1,000 9,866E-04 0,01308176 ! skin development GO:0043588 11 11 1,000 9,866E-04 0,01298832 ! signal complex assembly GO:0007172 11 11 1,000 9,866E-04 0,0128962 ! protein amino acid acetylation GO:0006473 11 11 1,000 9,866E-04 0,01280539 ! regulation of transmembrane transporter activity GO:0022898 11 11 1,000 9,866E-04 0,01271584 GO:0032412|regulation of ion transmembrane transporter activity, GO:0032409|regulation of transporter activity, ! cellular response to starvation GO:0009267 11 11 1,000 9,866E-04 0,01262753 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 11 11 1,000 9,866E-04 0,01254045 ! G1/S transition checkpoint GO:0031575 12 11 1,000 9,866E-04 0,01245455 ! interaction with host GO:0051701 11 11 1,000 9,866E-04 0,01236983 ! regulation of monooxygenase activity GO:0032768 11 11 1,000 9,866E-04 0,01228625 ! regulation of cellular carbohydrate metabolic process GO:0010675 11 11 1,000 9,866E-04 0,01220379 GO:0006109|regulation of carbohydrate metabolic process, ! hindbrain development GO:0030902 11 11 1,000 9,866E-04 0,01212243 ! negative regulation of lymphocyte activation GO:0051250 11 11 1,000 9,866E-04 0,01204215 ! regulation of peptidase activity GO:0052547 46 46 2,000 1,001E-03 0,01213616 ! actin filament organization GO:0007015 50 48 2,000 1,134E-03 0,013657 ! positive regulation of protein catabolic process GO:0045732 12 12 1,000 1,181E-03 0,0141307 ! negative regulation of peptidase activity GO:0010466 12 12 1,000 1,181E-03 0,01403954 ! positive regulation of endocytosis GO:0045807 12 12 1,000 1,181E-03 0,01394954 ! regulation of insulin secretion GO:0050796 12 12 1,000 1,181E-03 0,01386069 ! somitogenesis GO:0001756 13 12 1,000 1,181E-03 0,01377296 ! cellular monovalent inorganic cation homeostasis GO:0030004 12 12 1,000 1,181E-03 0,01368634 ! skeletal muscle tissue development GO:0007519 50 49 2,000 1,204E-03 0,01387041 GO:0060538|skeletal muscle organ development, ! regulation of DNA metabolic process GO:0051052 51 50 2,000 1,277E-03 0,0146211 ! regulation of neurogenesis GO:0050767 51 50 2,000 1,277E-03 0,01453084 ! anterior/posterior pattern formation GO:0009952 51 50 2,000 1,277E-03 0,0144417 ! positive regulation of DNA replication GO:0045740 14 13 1,000 1,392E-03 0,01563917 ! negative regulation of hormone secretion GO:0046888 13 13 1,000 1,392E-03 0,01554439 ! mitochondrial membrane organization GO:0007006 13 13 1,000 1,392E-03 0,01545075 ! negative regulation of DNA replication GO:0008156 13 13 1,000 1,392E-03 0,01535823 ! actin filament bundle formation GO:0051017 13 13 1,000 1,392E-03 0,01526681 ! negative regulation of protein catabolic process GO:0042177 13 13 1,000 1,392E-03 0,01517648 ! cell aging GO:0007569 13 13 1,000 1,392E-03 0,0150872 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 13 13 1,000 1,392E-03 0,01499897 ! regulation of peptide secretion GO:0002791 13 13 1,000 1,392E-03 0,01491177 ! regulation of axonogenesis GO:0050770 14 13 1,000 1,392E-03 0,01482557 ! negative regulation of intracellular transport GO:0032387 13 13 1,000 1,392E-03 0,01474037 ! negative regulation of leukocyte activation GO:0002695 13 13 1,000 1,392E-03 0,01465614 ! purine nucleotide catabolic process GO:0006195 13 13 1,000 1,392E-03 0,01457287 ! tissue homeostasis GO:0001894 13 13 1,000 1,392E-03 0,01449053 GO:0048871|multicellular organismal homeostasis, ! response to light stimulus GO:0009416 53 52 2,000 1,432E-03 0,01482419 ! response to hypoxia GO:0001666 53 53 2,000 1,513E-03 0,01558004 ! response to oxygen levels GO:0070482 55 54 2,000 1,598E-03 0,01635677 ! protein amino acid acylation GO:0043543 14 14 1,000 1,619E-03 0,01648727 ! regulation of neuron projection development GO:0010975 15 14 1,000 1,619E-03 0,01639668 ! base-excision repair GO:0006284 14 14 1,000 1,619E-03 0,01630708 ! group transfer coenzyme metabolic process GO:0006752 14 14 1,000 1,619E-03 0,01621845 ! regulation of nervous system development GO:0051960 57 56 2,000 1,775E-03 0,01768152 ! protein import into nucleus, translocation GO:0000060 15 15 1,000 1,863E-03 0,01846227 ! regulation of transcription factor import into nucleus GO:0042990 15 15 1,000 1,863E-03 0,01836355 ! response to starvation GO:0042594 15 15 1,000 1,863E-03 0,01826587 ! response to ionizing radiation GO:0010212 16 15 1,000 1,863E-03 0,01816922 ! negative regulation of transcription factor activity GO:0043433 16 15 1,000 1,863E-03 0,0180736 GO:0090048|negative regulation of transcription regulator activity, ! negative regulation of cell activation GO:0050866 15 15 1,000 1,863E-03 0,01797897 ! regulation of binding GO:0051098 60 57 2,000 1,868E-03 0,01793067 ! regulation of cell development GO:0060284 60 59 2,000 2,063E-03 0,01970246 ! negative regulation of adenylate cyclase activity GO:0007194 16 16 1,000 2,124E-03 0,02017491 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of mitosis GO:0045840 16 16 1,000 2,124E-03 0,02007145 GO:0051785|positive regulation of nuclear division, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 16 16 1,000 2,124E-03 0,01996905 ! segmentation GO:0035282 17 16 1,000 2,124E-03 0,01986768 ! triglyceride metabolic process GO:0006641 16 16 1,000 2,124E-03 0,01976734 ! cellular response to nutrient levels GO:0031669 16 16 1,000 2,124E-03 0,01966801 ! regulation of cell morphogenesis involved in differentiation GO:0010769 17 16 1,000 2,124E-03 0,01956967 ! regulation of fibroblast proliferation GO:0048145 17 17 1,000 2,4E-03 0,02200891 ! positive regulation of cell adhesion GO:0045785 17 17 1,000 2,4E-03 0,02189996 ! myelination GO:0042552 17 17 1,000 2,4E-03 0,02179208 ! regulation of transmembrane transport GO:0034762 17 17 1,000 2,4E-03 0,02168525 ! glucose transport GO:0015758 17 17 1,000 2,4E-03 0,02157947 ! regulation of oxidoreductase activity GO:0051341 17 17 1,000 2,4E-03 0,02147472 ! regulation of cell projection organization GO:0031344 19 18 1,000 2,693E-03 0,02397733 ! hexose transport GO:0008645 18 18 1,000 2,693E-03 0,02386205 GO:0015749|monosaccharide transport, ! neutral lipid metabolic process GO:0006638 18 18 1,000 2,693E-03 0,02374788 GO:0006639|acylglycerol metabolic process, ! negative regulation of DNA binding GO:0043392 19 18 1,000 2,693E-03 0,02363479 ! B cell differentiation GO:0030183 18 18 1,000 2,693E-03 0,02352278 ! cellular response to extracellular stimulus GO:0031668 18 18 1,000 2,693E-03 0,02341182 ! ensheathment of neurons GO:0007272 18 18 1,000 2,693E-03 0,02330191 GO:0008366|axon ensheathment, ! negative regulation of catabolic process GO:0009895 18 18 1,000 2,693E-03 0,02319302 ! symbiosis, encompassing mutualism through parasitism GO:0044403 18 18 1,000 2,693E-03 0,02308515 ! positive regulation of cellular component organization GO:0051130 65 65 2,000 2,724E-03 0,02324116 ! striated muscle tissue development GO:0014706 69 67 2,000 2,97E-03 0,02522334 ! negative regulation of cell differentiation GO:0045596 68 67 2,000 2,97E-03 0,02510764 ! negative regulation of DNA metabolic process GO:0051053 19 19 1,000 3,002E-03 0,02526131 ! regulation of pH GO:0006885 19 19 1,000 3,002E-03 0,02514648 ! peptidyl-tyrosine phosphorylation GO:0018108 20 19 1,000 3,002E-03 0,0250327 ! ribonucleoside metabolic process GO:0009119 19 19 1,000 3,002E-03 0,02491994 ! peripheral nervous system development GO:0007422 19 19 1,000 3,002E-03 0,02480819 ! regulation of protein stability GO:0031647 19 19 1,000 3,002E-03 0,02469744 ! response to radiation GO:0009314 70 68 2,000 3,098E-03 0,02537476 ! regulation of cell size GO:0008361 68 68 2,000 3,098E-03 0,02526248 ! regionalization GO:0003002 70 69 2,000 3,229E-03 0,02621744 ! regulation of mitotic cell cycle GO:0007346 72 69 2,000 3,229E-03 0,02610245 ! negative regulation of binding GO:0051100 21 20 1,000 3,326E-03 0,02676988 ! organic ether metabolic process GO:0018904 20 20 1,000 3,326E-03 0,02665349 GO:0006662|glycerol ether metabolic process, ! positive regulation of gene-specific transcription GO:0043193 20 20 1,000 3,326E-03 0,0265381 ! protein targeting to membrane GO:0006612 22 20 1,000 3,326E-03 0,02642371 ! peptidyl-tyrosine modification GO:0018212 21 20 1,000 3,326E-03 0,02631031 ! muscle tissue development GO:0060537 72 70 2,000 3,364E-03 0,02649417 ! regulation of cell migration GO:0030334 71 71 2,000 3,502E-03 0,02746468 ! positive regulation of hydrolase activity GO:0051345 72 72 2,000 3,644E-03 0,02845383 ! G1/S transition of mitotic cell cycle GO:0000082 21 21 1,000 3,666E-03 0,02851175 ! mammary gland development GO:0030879 23 21 1,000 3,666E-03 0,02839196 ! receptor-mediated endocytosis GO:0006898 21 21 1,000 3,666E-03 0,02827316 ! regulation of protein import into nucleus GO:0042306 21 21 1,000 3,666E-03 0,02815536 ! regulation of action potential in neuron GO:0019228 21 21 1,000 3,666E-03 0,02803853 ! regulation of multicellular organism growth GO:0040014 21 21 1,000 3,666E-03 0,02792267 ! positive regulation of transcription factor activity GO:0051091 22 22 1,000 4,022E-03 0,03050589 GO:0090047|positive regulation of transcription regulator activity, ! positive regulation of DNA metabolic process GO:0051054 23 22 1,000 4,022E-03 0,03038086 ! hormone-mediated signaling GO:0009755 22 22 1,000 4,022E-03 0,03025686 ! maintenance of protein location in cell GO:0032507 23 22 1,000 4,022E-03 0,03013386 ! regulation of hormone secretion GO:0046883 23 23 1,000 4,393E-03 0,03278135 ! mitotic cell cycle checkpoint GO:0007093 24 23 1,000 4,393E-03 0,03264916 ! monovalent inorganic cation homeostasis GO:0055067 23 23 1,000 4,393E-03 0,03251804 ! calcium-mediated signaling GO:0019722 23 23 1,000 4,393E-03 0,03238797 ! regulation of locomotion GO:0040012 79 79 2,000 4,733E-03 0,0347532 ! mitochondrial transport GO:0006839 24 24 1,000 4,78E-03 0,03495726 ! regulation of action potential GO:0001508 24 24 1,000 4,78E-03 0,03481909 ! T cell differentiation GO:0030217 24 24 1,000 4,78E-03 0,034682 ! nucleotide catabolic process GO:0009166 24 24 1,000 4,78E-03 0,03454599 ! maintenance of protein location GO:0045185 25 24 1,000 4,78E-03 0,03441105 ! glucan metabolic process GO:0044042 25 24 1,000 4,78E-03 0,03427715 GO:0006073|cellular glucan metabolic process, GO:0005977|glycogen metabolic process, ! negative regulation of secretion GO:0051048 26 25 1,000 5,181E-03 0,03701316 ! positive regulation of DNA binding GO:0043388 26 25 1,000 5,181E-03 0,03687025 ! regulation of endocytosis GO:0030100 25 25 1,000 5,181E-03 0,03672845 ! endosome transport GO:0016197 25 25 1,000 5,181E-03 0,03658772 ! regulation of T cell proliferation GO:0042129 25 25 1,000 5,181E-03 0,03644808 ! heart morphogenesis GO:0003007 25 25 1,000 5,181E-03 0,03630949 ! negative regulation of immune system process GO:0002683 25 25 1,000 5,181E-03 0,03617195 ! positive regulation of binding GO:0051099 27 26 1,000 5,598E-03 0,03893303 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 26 26 1,000 5,598E-03 0,03878667 ! regulation of T cell differentiation GO:0045580 26 26 1,000 5,598E-03 0,0386414 ! double-strand break repair GO:0006302 27 26 1,000 5,598E-03 0,03849722 ! maintenance of location in cell GO:0051651 27 26 1,000 5,598E-03 0,0383541 ! synapse organization GO:0050808 26 26 1,000 5,598E-03 0,03821205 ! regulation of anatomical structure morphogenesis GO:0022603 90 86 2,000 6,001E-03 0,04081143 ! energy reserve metabolic process GO:0006112 28 27 1,000 6,03E-03 0,04085502 ! cAMP-mediated signaling GO:0019933 27 27 1,000 6,03E-03 0,04070536 ! activation of caspase activity GO:0006919 27 27 1,000 6,03E-03 0,0405568 ! carbohydrate transport GO:0008643 28 28 1,000 6,476E-03 0,04340032 ! keratinocyte differentiation GO:0030216 28 28 1,000 6,476E-03 0,04324308 ! histone modification GO:0016570 28 28 1,000 6,476E-03 0,04308696 ! regulation of mast cell proliferation GO:0070666 28 28 1,000 6,476E-03 0,04293197 ! viral reproductive process GO:0022415 29 29 1,000 6,937E-03 0,04582291 ! regulation of lymphocyte proliferation GO:0050670 29 29 1,000 6,937E-03 0,04565926 GO:0032944|regulation of mononuclear cell proliferation, GO:0070663|regulation of leukocyte proliferation, ! covalent chromatin modification GO:0016569 29 29 1,000 6,937E-03 0,04549677 ! negative regulation of cell cycle GO:0045786 92 91 2,000 7,02E-03 0,04588014 ! positive regulation of peptidase activity GO:0010952 30 30 1,000 7,412E-03 0,04827151 GO:0043280|positive regulation of caspase activity, ! activation of phospholipase C activity GO:0007202 30 30 1,000 7,412E-03 0,04810154 GO:0010863|positive regulation of phospholipase C activity, ! pattern specification process GO:0007389 96 94 2,000 7,678E-03 0,04965266 ! skeletal muscle fiber development GO:0048741 31 31 1,000 7,902E-03 0,05092166 ! B cell activation GO:0042113 31 31 1,000 7,902E-03 0,05074423 ! positive regulation of phospholipase activity GO:0010518 31 31 1,000 7,902E-03 0,05056804 ! aging GO:0007568 32 31 1,000 7,902E-03 0,05039306 ! nucleoside metabolic process GO:0009116 31 31 1,000 7,902E-03 0,05021929 ! epidermal cell differentiation GO:0009913 31 31 1,000 7,902E-03 0,05004672 ! negative regulation of cell motion GO:0051271 31 31 1,000 7,902E-03 0,04987532 ! negative regulation of cell growth GO:0030308 32 32 1,000 8,406E-03 0,05287587 ! muscle fiber development GO:0048747 32 32 1,000 8,406E-03 0,05269602 ! regulation of phospholipase activity GO:0010517 32 32 1,000 8,406E-03 0,05251739 ! regulation of vesicle-mediated transport GO:0060627 33 32 1,000 8,406E-03 0,05233996 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 32 32 1,000 8,406E-03 0,05216373 ! regulation of lymphocyte differentiation GO:0045619 32 32 1,000 8,406E-03 0,05198869 ! positive regulation of lipase activity GO:0060193 32 32 1,000 8,406E-03 0,05181481 ! maintenance of location GO:0051235 33 32 1,000 8,406E-03 0,0516421 ! negative regulation of cell size GO:0045792 33 33 1,000 8,924E-03 0,05464356 ! regulation of neuron differentiation GO:0045664 34 33 1,000 8,924E-03 0,05446262 ! regulation of neuron apoptosis GO:0043523 34 33 1,000 8,924E-03 0,05428288 ! muscle organ development GO:0007517 102 100 2,000 9,101E-03 0,05517693 ! regulation of angiogenesis GO:0045765 35 34 1,000 9,457E-03 0,05714299 ! cellular polysaccharide metabolic process GO:0044264 35 34 1,000 9,457E-03 0,05695625 ! viral reproduction GO:0016032 34 34 1,000 9,457E-03 0,05677073 ! multicellular organism reproduction GO:0032504 36 35 1,000 0,01000277 0,05985424 GO:0048609|reproductive process in a multicellular organism, ! regulation of cell morphogenesis GO:0022604 38 35 1,000 0,01000277 0,05966053 ! positive regulation of phosphorylation GO:0042327 35 35 1,000 0,01000277 0,05946808 ! regulation of mitosis GO:0007088 37 36 1,000 0,01056265 0,06259473 GO:0051783|regulation of nuclear division, ! positive regulation of phosphorus metabolic process GO:0010562 36 36 1,000 0,01056265 0,06239411 GO:0045937|positive regulation of phosphate metabolic process, ! positive regulation of organelle organization GO:0010638 36 36 1,000 0,01056265 0,06219476 ! heterocycle catabolic process GO:0046700 36 36 1,000 0,01056265 0,06199669 ! regulation of lipase activity GO:0060191 36 36 1,000 0,01056265 0,06179988 ! regulation of adenylate cyclase activity GO:0045761 37 37 1,000 0,01113617 0,06494923 GO:0031279|regulation of cyclase activity, GO:0051339|regulation of lyase activity, ! meiosis GO:0007126 37 37 1,000 0,01113617 0,06474434 GO:0051327|M phase of meiotic cell cycle, ! negative regulation of protein kinase activity GO:0006469 37 37 1,000 0,01113617 0,06454074 ! response to drug GO:0042493 37 37 1,000 0,01113617 0,06433842 ! lung development GO:0030324 38 37 1,000 0,01113617 0,06413736 ! negative regulation of growth GO:0045926 37 37 1,000 0,01113617 0,06393756 ! positive regulation of secretion GO:0051047 39 38 1,000 0,01172321 0,06709897 ! negative regulation of kinase activity GO:0033673 38 38 1,000 0,01172321 0,06689123 ! chromosome segregation GO:0007059 38 38 1,000 0,01172321 0,06668478 ! meiotic cell cycle GO:0051321 38 38 1,000 0,01172321 0,06647959 ! axon guidance GO:0007411 39 38 1,000 0,01172321 0,06627567 ! regulation of cAMP biosynthetic process GO:0030817 39 39 1,000 0,01232364 0,06945711 ! respiratory tube development GO:0030323 40 39 1,000 0,01232364 0,06924535 ! nucleotide-excision repair GO:0006289 40 39 1,000 0,01232364 0,06903487 ! respiratory system development GO:0060541 40 39 1,000 0,01232364 0,06882568 ! lymphocyte differentiation GO:0030098 39 39 1,000 0,01232364 0,06861774 ! regulation of cAMP metabolic process GO:0030814 40 40 1,000 0,01293736 0,07181793 ! negative regulation of transferase activity GO:0051348 40 40 1,000 0,01293736 0,07160226 ! regulation of nucleotide biosynthetic process GO:0030808 41 41 1,000 0,01356423 0,07484695 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! regulation of cyclic nucleotide metabolic process GO:0030799 42 42 1,000 0,01420415 0,07814403 ! protein ubiquitination GO:0016567 43 42 1,000 0,01420415 0,07791145 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 43 43 1,000 0,01485699 0,08125054 ! regulation of nucleotide metabolic process GO:0006140 43 43 1,000 0,01485699 0,08101016 ! protein import into nucleus GO:0006606 44 44 1,000 0,01552264 0,08439003 ! phosphoinositide-mediated signaling GO:0048015 45 45 1,000 0,01620097 0,0878188 ! nuclear import GO:0051170 45 45 1,000 0,01620097 0,08756127 ! Wnt receptor signaling pathway GO:0016055 46 45 1,000 0,01620097 0,08730524 ! cyclic-nucleotide-mediated signaling GO:0019935 46 46 1,000 0,01689188 0,0907631 ! regulation of membrane potential GO:0042391 46 46 1,000 0,01689188 0,09049925 ! regulation of cell cycle process GO:0010564 50 48 1,000 0,01831097 0,09781775 ! protein localization in nucleus GO:0034504 48 48 1,000 0,01831097 0,09753504 ! leukocyte differentiation GO:0002521 50 49 1,000 0,01903892 0,10112027 ! ossification GO:0001503 50 49 1,000 0,01903892 0,1008297 GO:0060348|bone development, ! gland development GO:0048732 51 49 1,000 0,01903892 0,10054079 ! T cell activation GO:0042110 51 50 1,000 0,01977899 0,10415052 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 50 50 1,000 0,01977899 0,1038538 ! anatomical structure homeostasis GO:0060249 51 50 1,000 0,01977899 0,10355876 ! protein modification by small protein conjugation GO:0032446 52 51 1,000 0,02053107 0,10719195 ! interphase of mitotic cell cycle GO:0051329 52 51 1,000 0,02053107 0,10688915 GO:0051325|interphase, ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 52 52 1,000 0,02129504 0,11055426 ! cell fate commitment GO:0045165 52 52 1,000 0,02129504 0,11024371 ! rRNA transcription GO:0009303 5 5 0,000 0,02161925 0,11160861 ! positive regulation of protein ubiquitination GO:0031398 5 5 0,000 0,02161925 0,11129685 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 5 5 0,000 0,02161925 0,11098683 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 5 5 0,000 0,02161925 0,11067853 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! neuron fate specification GO:0048665 5 5 0,000 0,02161925 0,11037195 ! hemoglobin biosynthetic process GO:0042541 5 5 0,000 0,02161925 0,11006705 ! reproductive cellular process GO:0048610 5 5 0,000 0,02161925 0,10976384 ! negative regulation of blood pressure GO:0045776 6 5 0,000 0,02161925 0,10946229 ! prostate gland development GO:0030850 5 5 0,000 0,02161925 0,10916239 ! water transport GO:0006833 5 5 0,000 0,02161925 0,10886413 GO:0042044|fluid transport, ! forebrain regionalization GO:0021871 5 5 0,000 0,02161925 0,1085675 ! DNA synthesis during DNA repair GO:0000731 5 5 0,000 0,02161925 0,10827248 ! positive regulation of B cell proliferation GO:0030890 5 5 0,000 0,02161925 0,10797906 ! glycerol metabolic process GO:0006071 5 5 0,000 0,02161925 0,10768722 ! regulation of cellular amine metabolic process GO:0033238 5 5 0,000 0,02161925 0,10739696 GO:0042053|regulation of dopamine metabolic process, GO:0042069|regulation of catecholamine metabolic process, ! meiotic prophase I GO:0007128 5 5 0,000 0,02161925 0,10710826 GO:0051324|prophase, ! cell volume homeostasis GO:0006884 5 5 0,000 0,02161925 0,10682111 ! regulation of long-term neuronal synaptic plasticity GO:0048169 5 5 0,000 0,02161925 0,10653549 ! filopodium assembly GO:0046847 7 5 0,000 0,02161925 0,10625139 GO:0030035|microspike assembly, ! CTP metabolic process GO:0046036 5 5 0,000 0,02161925 0,10596881 GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0006241|CTP biosynthetic process, ! Golgi to endosome transport GO:0006895 5 5 0,000 0,02161925 0,10568773 ! GTP metabolic process GO:0046039 5 5 0,000 0,02161925 0,10540813 ! establishment of tissue polarity GO:0007164 5 5 0,000 0,02161925 0,10513001 ! mRNA stabilization GO:0048255 5 5 0,000 0,02161925 0,10485335 GO:0043489|RNA stabilization, ! positive regulation of cell-cell adhesion GO:0022409 5 5 0,000 0,02161925 0,10457814 ! regulation of neurotransmitter secretion GO:0046928 5 5 0,000 0,02161925 0,10430438 GO:0001956|positive regulation of neurotransmitter secretion, ! neurotransmitter uptake GO:0001504 5 5 0,000 0,02161925 0,10403204 ! social behavior GO:0035176 5 5 0,000 0,02161925 0,10376113 ! macrophage chemotaxis GO:0048246 6 5 0,000 0,02161925 0,10349162 ! 2-oxoglutarate metabolic process GO:0006103 5 5 0,000 0,02161925 0,1032235 ! memory GO:0007613 5 5 0,000 0,02161925 0,10295678 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 5 5 0,000 0,02161925 0,10269142 ! membrane hyperpolarization GO:0060081 5 5 0,000 0,02161925 0,10242744 ! response to lipid GO:0033993 5 5 0,000 0,02161925 0,1021648 ! erythrocyte maturation GO:0043249 5 5 0,000 0,02161925 0,10190351 ! hippocampus development GO:0021766 6 5 0,000 0,02161925 0,10164355 ! regulation of carbohydrate biosynthetic process GO:0043255 5 5 0,000 0,02161925 0,10138492 ! glucocorticoid metabolic process GO:0008211 5 5 0,000 0,02161925 0,10112759 ! middle ear morphogenesis GO:0042474 5 5 0,000 0,02161925 0,10087158 ! amyloid precursor protein catabolic process GO:0042987 5 5 0,000 0,02161925 0,10061685 ! mechanosensory behavior GO:0007638 5 5 0,000 0,02161925 0,10036341 ! heart looping GO:0001947 5 5 0,000 0,02161925 0,10011124 ! negative regulation of endocytosis GO:0045806 5 5 0,000 0,02161925 0,09986033 ! response to interferon-gamma GO:0034341 5 5 0,000 0,02161925 0,09961068 ! pseudouridine synthesis GO:0001522 5 5 0,000 0,02161925 0,09936228 ! endocrine pancreas development GO:0031018 5 5 0,000 0,02161925 0,09911511 ! pH reduction GO:0045851 5 5 0,000 0,02161925 0,09886916 GO:0051452|intracellular pH reduction, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 5 5 0,000 0,02161925 0,09862444 ! lipopolysaccharide metabolic process GO:0008653 5 5 0,000 0,02161925 0,09838092 ! positive regulation of chemokine biosynthetic process GO:0045080 5 5 0,000 0,02161925 0,0981386 ! sphingoid biosynthetic process GO:0046520 5 5 0,000 0,02161925 0,09789748 GO:0046513|ceramide biosynthetic process, ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 5 5 0,000 0,02161925 0,09765753 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! thymic T cell selection GO:0045061 5 5 0,000 0,02161925 0,09741876 ! insulin-like growth factor receptor signaling pathway GO:0048009 5 5 0,000 0,02161925 0,09718115 ! photoreceptor cell maintenance GO:0045494 5 5 0,000 0,02161925 0,0969447 ! adrenal gland development GO:0030325 5 5 0,000 0,02161925 0,0967094 ! regulation of cardiac muscle hypertrophy GO:0010611 5 5 0,000 0,02161925 0,09647524 GO:0010612|regulation of cardiac muscle adaptation, GO:0014743|regulation of muscle hypertrophy, GO:0043502|regulation of muscle adaptation, ! melanocyte differentiation GO:0030318 5 5 0,000 0,02161925 0,0962422 GO:0050931|pigment cell differentiation, ! ovulation GO:0030728 5 5 0,000 0,02161925 0,09601029 ! astrocyte differentiation GO:0048708 5 5 0,000 0,02161925 0,0957795 ! mitochondrial respiratory chain complex assembly GO:0033108 5 5 0,000 0,02161925 0,09554981 GO:0032981|mitochondrial respiratory chain complex I assembly, GO:0010257|NADH dehydrogenase complex assembly, ! pituitary gland development GO:0021983 5 5 0,000 0,02161925 0,09532123 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 5 5 0,000 0,02161925 0,09509373 GO:0033135|regulation of peptidyl-serine phosphorylation, ! tyrosine metabolic process GO:0006570 5 5 0,000 0,02161925 0,09486732 ! cytoskeletal anchoring at plasma membrane GO:0007016 6 5 0,000 0,02161925 0,09464198 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 5 5 0,000 0,02161925 0,09441771 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, GO:0009164|nucleoside catabolic process, ! microtubule nucleation GO:0007020 5 5 0,000 0,02161925 0,0941945 ! regulation of interleukin-6 biosynthetic process GO:0045408 5 5 0,000 0,02161925 0,09397234 ! regulation of interleukin-8 biosynthetic process GO:0045414 5 5 0,000 0,02161925 0,09375123 ! indolalkylamine metabolic process GO:0006586 5 5 0,000 0,02161925 0,09353116 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! muscle cell migration GO:0014812 5 5 0,000 0,02161925 0,09331211 ! phasic smooth muscle contraction GO:0014821 5 5 0,000 0,02161925 0,09309409 ! central nervous system neuron axonogenesis GO:0021955 6 5 0,000 0,02161925 0,09287709 GO:0021952|central nervous system projection neuron axonogenesis, ! sister chromatid cohesion GO:0007062 5 5 0,000 0,02161925 0,0926611 ! response to ATP GO:0033198 5 5 0,000 0,02161925 0,09244611 ! regulation of type I interferon production GO:0032479 5 5 0,000 0,02161925 0,09223211 ! regulation of appetite GO:0032098 5 5 0,000 0,02161925 0,0920191 GO:0032095|regulation of response to food, ! vesicle fusion GO:0006906 5 5 0,000 0,02161925 0,09180708 ! paraxial mesoderm development GO:0048339 5 5 0,000 0,02161925 0,09159603 ! regulation of the force of heart contraction GO:0002026 5 5 0,000 0,02161925 0,09138595 ! maintenance of protein location in nucleus GO:0051457 5 5 0,000 0,02161925 0,09117682 ! neurotransmitter biosynthetic process GO:0042136 6 5 0,000 0,02161925 0,09096866 ! fear response GO:0042596 5 5 0,000 0,02161925 0,09076144 ! lens development in camera-type eye GO:0002088 5 5 0,000 0,02161925 0,09055516 ! retinol metabolic process GO:0042572 5 5 0,000 0,02161925 0,09034982 ! corticosteroid receptor signaling pathway GO:0031958 5 5 0,000 0,02161925 0,09014541 GO:0042921|glucocorticoid receptor signaling pathway, ! temperature homeostasis GO:0001659 5 5 0,000 0,02161925 0,08994192 ! positive regulation of exocytosis GO:0045921 6 5 0,000 0,02161925 0,08973935 ! parturition GO:0007567 5 5 0,000 0,02161925 0,08953769 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,02161925 0,08933693 ! regulation of vascular endothelial growth factor production GO:0010574 5 5 0,000 0,02161925 0,08913707 ! Schwann cell differentiation GO:0014037 5 5 0,000 0,02161925 0,08893811 ! acyl-CoA metabolic process GO:0006637 5 5 0,000 0,02161925 0,08874003 ! wound healing, spreading of epidermal cells GO:0035313 5 5 0,000 0,02161925 0,08854283 ! regulation of gliogenesis GO:0014013 5 5 0,000 0,02161925 0,0883465 GO:0045685|regulation of glial cell differentiation, ! positive regulation of peptide secretion GO:0002793 5 5 0,000 0,02161925 0,08815104 ! response to UV-B GO:0010224 5 5 0,000 0,02161925 0,08795645 ! oligodendrocyte development GO:0014003 5 5 0,000 0,02161925 0,08776271 ! hyaluronan metabolic process GO:0030212 5 5 0,000 0,02161925 0,08756983 ! activated T cell proliferation GO:0050798 5 5 0,000 0,02161925 0,08737779 ! interaction with symbiont GO:0051702 5 5 0,000 0,02161925 0,08718659 ! cellular extravasation GO:0045123 5 5 0,000 0,02161925 0,08699623 ! positive regulation of axonogenesis GO:0050772 5 5 0,000 0,02161925 0,08680669 ! peptidyl-asparagine modification GO:0018196 5 5 0,000 0,02161925 0,08661798 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! positive regulation of phagocytosis GO:0050766 5 5 0,000 0,02161925 0,08643009 ! regulation of insulin receptor signaling pathway GO:0046626 5 5 0,000 0,02161925 0,08624301 ! antigen processing and presentation of exogenous antigen GO:0019884 5 5 0,000 0,02161925 0,08605674 ! enucleate erythrocyte differentiation GO:0043353 6 5 0,000 0,02161925 0,08587128 ! response to amine stimulus GO:0014075 5 5 0,000 0,02161925 0,08568661 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 5 5 0,000 0,02161925 0,08550273 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 5 5 0,000 0,02161925 0,08531964 ! synaptic vesicle exocytosis GO:0016079 6 5 0,000 0,02161925 0,08513733 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 5 5 0,000 0,02161925 0,0849558 ! glycosylceramide metabolic process GO:0006677 5 5 0,000 0,02161925 0,08477505 ! neuron recognition GO:0008038 5 5 0,000 0,02161925 0,08459506 ! negative regulation of focal adhesion formation GO:0051895 6 5 0,000 0,02161925 0,08441583 ! decidualization GO:0046697 5 5 0,000 0,02161925 0,08423736 ! hair follicle maturation GO:0048820 5 5 0,000 0,02161925 0,08405965 ! phosphatidylinositol biosynthetic process GO:0006661 5 5 0,000 0,02161925 0,08388268 ! regulation of mitochondrial membrane potential GO:0051881 5 5 0,000 0,02161925 0,08370645 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 0,02161925 0,08353097 GO:0009155|purine deoxyribonucleotide catabolic process, ! regulation of interleukin-12 production GO:0032655 5 5 0,000 0,02161925 0,08335622 ! positive regulation of interleukin-6 production GO:0032755 5 5 0,000 0,02161925 0,0831822 ! positive regulation of monooxygenase activity GO:0032770 5 5 0,000 0,02161925 0,0830089 ! postreplication repair GO:0006301 5 5 0,000 0,02161925 0,08283633 ! spinal cord motor neuron differentiation GO:0021522 5 5 0,000 0,02161925 0,08266447 GO:0021517|ventral spinal cord development, ! cellular pigmentation GO:0033059 5 5 0,000 0,02161925 0,08249332 ! histone methylation GO:0016571 5 5 0,000 0,02161925 0,08232288 ! DNA methylation GO:0006306 5 5 0,000 0,02161925 0,08215314 GO:0006305|DNA alkylation, ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,02161925 0,0819841 ! positive regulation of immunoglobulin mediated immune response GO:0002891 5 5 0,000 0,02161925 0,08181575 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of interferon-gamma production GO:0032729 5 5 0,000 0,02161925 0,0816481 ! negative regulation of tumor necrosis factor production GO:0032720 5 5 0,000 0,02161925 0,08148113 ! intracellular cholesterol transport GO:0032367 5 5 0,000 0,02161925 0,08131484 GO:0032366|intracellular sterol transport, ! regulation of mast cell activation GO:0033003 5 5 0,000 0,02161925 0,08114923 ! morphogenesis of a polarized epithelium GO:0001738 5 5 0,000 0,02161925 0,08098429 ! regulation of hormone metabolic process GO:0032350 5 5 0,000 0,02161925 0,08082003 ! regulation of transcription from RNA polymerase III promoter GO:0006359 5 5 0,000 0,02161925 0,08065642 ! regulation of inflammatory response to antigenic stimulus GO:0002861 5 5 0,000 0,02161925 0,08049348 ! sterol catabolic process GO:0016127 5 5 0,000 0,02161925 0,08033119 GO:0006707|cholesterol catabolic process, ! negative regulation of oxidoreductase activity GO:0051354 5 5 0,000 0,02161925 0,08016956 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 5 5 0,000 0,02161925 0,08000858 ! detection of biotic stimulus GO:0009595 5 5 0,000 0,02161925 0,07984824 ! regulation of immune response to tumor cell GO:0002837 5 5 0,000 0,02161925 0,07968854 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 5 5 0,000 0,02161925 0,07952949 ! zymogen activation GO:0031638 5 5 0,000 0,02161925 0,07937106 ! positive regulation of interleukin-1 beta secretion GO:0050718 5 5 0,000 0,02161925 0,07921327 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 5 5 0,000 0,02161925 0,0790561 GO:0002820|negative regulation of adaptive immune response, ! cellular response to nutrient GO:0031670 5 5 0,000 0,02161925 0,07889955 ! peptidyl-histidine modification GO:0018202 5 5 0,000 0,02161925 0,07874362 ! nucleosome positioning GO:0016584 5 5 0,000 0,02161925 0,07858831 ! regulation of isotype switching GO:0045191 5 5 0,000 0,02161925 0,07843361 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 5 5 0,000 0,02161925 0,07827951 ! negative regulation of neurological system process GO:0031645 5 5 0,000 0,02161925 0,07812602 ! regulation of myoblast differentiation GO:0045661 5 5 0,000 0,02161925 0,07797314 ! glutathione biosynthetic process GO:0006750 5 5 0,000 0,02161925 0,07782084 ! NADPH regeneration GO:0006740 5 5 0,000 0,02161925 0,07766915 GO:0006098|pentose-phosphate shunt, ! positive regulation of erythrocyte differentiation GO:0045648 5 5 0,000 0,02161925 0,07751804 ! positive regulation of epidermis development GO:0045684 5 5 0,000 0,02161925 0,07736752 ! positive regulation of leukocyte chemotaxis GO:0002690 5 5 0,000 0,02161925 0,07721758 GO:0002688|regulation of leukocyte chemotaxis, ! musculoskeletal movement GO:0050881 5 5 0,000 0,02161925 0,07706823 GO:0050879|multicellular organismal movement, ! neuromuscular process controlling posture GO:0050884 5 5 0,000 0,02161925 0,07691944 ! sarcomere organization GO:0045214 5 5 0,000 0,02161925 0,07677124 ! regulation of epidermal cell differentiation GO:0045604 5 5 0,000 0,02161925 0,0766236 ! activation of NF-kappaB-inducing kinase activity GO:0007250 5 5 0,000 0,02161925 0,07647653 ! negative regulation of glucose transport GO:0010829 5 5 0,000 0,02161925 0,07633002 GO:0046325|negative regulation of glucose import, ! positive regulation of T-helper cell differentiation GO:0045624 5 5 0,000 0,02161925 0,07618408 GO:0045622|regulation of T-helper cell differentiation, ! oocyte differentiation GO:0009994 5 5 0,000 0,02161925 0,07603869 GO:0048599|oocyte development, ! dopamine biosynthetic process GO:0042416 5 5 0,000 0,02161925 0,07589385 ! regulation of protein homodimerization activity GO:0043496 6 5 0,000 0,02161925 0,07574957 ! spleen development GO:0048536 5 5 0,000 0,02161925 0,07560583 ! male genitalia development GO:0030539 5 5 0,000 0,02161925 0,07546264 ! nicotinamide nucleotide biosynthetic process GO:0019359 5 5 0,000 0,02161925 0,07531999 ! quaternary ammonium group transport GO:0015697 5 5 0,000 0,02161925 0,07517787 ! thyroid hormone metabolic process GO:0042403 5 5 0,000 0,02161925 0,07503629 ! leukocyte mediated cytotoxicity GO:0001909 5 5 0,000 0,02161925 0,07489525 ! positive regulation of viral reproduction GO:0048524 5 5 0,000 0,02161925 0,07475473 ! removal of superoxide radicals GO:0019430 6 5 0,000 0,02161925 0,07461474 ! myeloid cell homeostasis GO:0002262 5 5 0,000 0,02161925 0,07447528 ! regulation of fatty acid oxidation GO:0046320 5 5 0,000 0,02161925 0,07433633 ! regulation of Rac protein signal transduction GO:0035020 5 5 0,000 0,02161925 0,0741979 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,02161925 0,07405999 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 5 5 0,000 0,02161925 0,07392258 ! blastocyst formation GO:0001825 5 5 0,000 0,02161925 0,07378569 ! regulation of fibrinolysis GO:0051917 5 5 0,000 0,02161925 0,0736493 ! embryonic gut development GO:0048566 5 5 0,000 0,02161925 0,07351342 ! negative regulation of organic acid transport GO:0032891 5 5 0,000 0,02161925 0,07337803 ! pyrimidine base metabolic process GO:0006206 5 5 0,000 0,02161925 0,07324315 ! activation of innate immune response GO:0002218 5 5 0,000 0,02161925 0,07310876 GO:0002758|innate immune response-activating signal transduction, ! positive regulation of blood vessel endothelial cell migration GO:0043536 5 5 0,000 0,02161925 0,07297486 ! catecholamine transport GO:0051937 5 5 0,000 0,02161925 0,07284145 ! negative regulation of blood vessel endothelial cell migration GO:0043537 5 5 0,000 0,02161925 0,07270853 ! regulation of NF-kappaB import into nucleus GO:0042345 5 5 0,000 0,02161925 0,07257609 ! muscle adaptation GO:0043500 5 5 0,000 0,02161925 0,07244413 ! positive regulation of actin filament bundle formation GO:0032233 5 5 0,000 0,02161925 0,07231265 ! embryonic heart tube development GO:0035050 5 5 0,000 0,02161925 0,07218165 ! cardiac cell differentiation GO:0035051 6 5 0,000 0,02161925 0,07205113 ! positive regulation of homeostatic process GO:0032846 5 5 0,000 0,02161925 0,07192107 ! defense response to fungus GO:0050832 5 5 0,000 0,02161925 0,07179148 ! lysogeny GO:0030069 5 5 0,000 0,02161925 0,07166236 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 5 5 0,000 0,02161925 0,0715337 ! B cell receptor signaling pathway GO:0050853 5 5 0,000 0,02161925 0,07140551 ! positive regulation of smooth muscle contraction GO:0045987 5 5 0,000 0,02161925 0,07127777 ! response to nicotine GO:0035094 5 5 0,000 0,02161925 0,07115049 ! establishment of cell polarity GO:0030010 5 5 0,000 0,02161925 0,07102366 ! mitochondrion localization GO:0051646 5 5 0,000 0,02161925 0,07089728 ! nucleus localization GO:0051647 5 5 0,000 0,02161925 0,07077135 ! regulation of synapse structure and activity GO:0050803 5 5 0,000 0,02161925 0,07064587 ! regulation of T cell activation GO:0050863 53 53 1,000 0,0220708 0,07199378 ! protein amino acid dephosphorylation GO:0006470 55 54 1,000 0,02285823 0,07443061 ! hormone metabolic process GO:0042445 55 54 1,000 0,02285823 0,07429934 ! in utero embryonic development GO:0001701 55 55 1,000 0,02365723 0,07676106 ! regulation of cell adhesion GO:0030155 56 55 1,000 0,02365723 0,07662616 ! protein modification by small protein conjugation or removal GO:0070647 56 55 1,000 0,02365723 0,07649173 ! reproductive developmental process GO:0003006 56 56 1,000 0,02446769 0,07897366 ! extracellular structure organization GO:0043062 56 56 1,000 0,02446769 0,07883559 ! ATP metabolic process GO:0046034 57 57 1,000 0,0252895 0,08134127 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 6 6 0,000 0,02588854 0,08312298 ! oligosaccharide biosynthetic process GO:0009312 6 6 0,000 0,02588854 0,08297841 ! tRNA modification GO:0006400 6 6 0,000 0,02588854 0,08283435 ! somatic diversification of immune receptors via somatic mutation GO:0002566 6 6 0,000 0,02588854 0,08269079 GO:0016446|somatic hypermutation of immunoglobulin genes, ! 'de novo' posttranslational protein folding GO:0051084 6 6 0,000 0,02588854 0,08254773 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 6 6 0,000 0,02588854 0,08240516 ! negative regulation of cellular catabolic process GO:0031330 6 6 0,000 0,02588854 0,08226308 ! regulation of S phase GO:0033261 6 6 0,000 0,02588854 0,08212149 ! myotube differentiation GO:0014902 6 6 0,000 0,02588854 0,08198039 ! regulation of B cell proliferation GO:0030888 6 6 0,000 0,02588854 0,08183977 ! bone remodeling GO:0046849 6 6 0,000 0,02588854 0,08169964 ! N-glycan processing GO:0006491 6 6 0,000 0,02588854 0,08155998 ! regulation of lipid kinase activity GO:0043550 6 6 0,000 0,02588854 0,0814208 ! glycosaminoglycan catabolic process GO:0006027 6 6 0,000 0,02588854 0,08128209 ! negative regulation of JAK-STAT cascade GO:0046426 6 6 0,000 0,02588854 0,08114386 ! retina development in camera-type eye GO:0060041 6 6 0,000 0,02588854 0,08100609 ! RNA methylation GO:0001510 6 6 0,000 0,02588854 0,08086879 ! cartilage condensation GO:0001502 7 6 0,000 0,02588854 0,08073196 ! regulation of activated T cell proliferation GO:0046006 6 6 0,000 0,02588854 0,08059559 ! regulation of positive chemotaxis GO:0050926 6 6 0,000 0,02588854 0,08045968 GO:0050927|positive regulation of positive chemotaxis, ! succinate metabolic process GO:0006105 7 6 0,000 0,02588854 0,08032422 ! artery development GO:0060840 6 6 0,000 0,02588854 0,08018922 GO:0048844|artery morphogenesis, ! positive regulation of neurotransmitter transport GO:0051590 6 6 0,000 0,02588854 0,08005468 ! bile acid metabolic process GO:0008206 6 6 0,000 0,02588854 0,07992058 ! androgen metabolic process GO:0008209 6 6 0,000 0,02588854 0,07978694 ! estrogen metabolic process GO:0008210 6 6 0,000 0,02588854 0,07965374 ! limbic system development GO:0021761 7 6 0,000 0,02588854 0,07952098 ! cytoplasmic sequestering of transcription factor GO:0042994 6 6 0,000 0,02588854 0,07938867 ! positive regulation of heart contraction GO:0045823 6 6 0,000 0,02588854 0,07925679 ! positive regulation of gene expression, epigenetic GO:0045815 6 6 0,000 0,02588854 0,07912535 ! pathogenesis GO:0009405 6 6 0,000 0,02588854 0,07899435 ! negative regulation of protein amino acid phosphorylation GO:0001933 6 6 0,000 0,02588854 0,07886378 ! regulation of chemokine biosynthetic process GO:0045073 6 6 0,000 0,02588854 0,07873364 ! inositol phosphate-mediated signaling GO:0048016 6 6 0,000 0,02588854 0,07860393 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 6 6 0,000 0,02588854 0,07847465 ! arginine metabolic process GO:0006525 6 6 0,000 0,02588854 0,07834579 GO:0006527|arginine catabolic process, ! regulation of catecholamine secretion GO:0050433 6 6 0,000 0,02588854 0,07821736 ! oligodendrocyte differentiation GO:0048709 6 6 0,000 0,02588854 0,07808934 ! glutamate catabolic process GO:0006538 7 6 0,000 0,02588854 0,07796175 ! telomere maintenance via telomerase GO:0007004 6 6 0,000 0,02588854 0,07783456 GO:0010833|telomere maintenance via telomere lengthening, ! L-phenylalanine metabolic process GO:0006558 6 6 0,000 0,02588854 0,0777078 GO:0006559|L-phenylalanine catabolic process, ! glucan biosynthetic process GO:0009250 6 6 0,000 0,02588854 0,07758144 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 6 6 0,000 0,02588854 0,0774555 ! V(D)J recombination GO:0033151 6 6 0,000 0,02588854 0,07732996 ! focal adhesion formation GO:0048041 7 6 0,000 0,02588854 0,07720484 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 0,02588854 0,07708011 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 6 6 0,000 0,02588854 0,07695579 ! negative regulation of endothelial cell migration GO:0010596 6 6 0,000 0,02588854 0,07683187 ! regulation of heart rate GO:0002027 6 6 0,000 0,02588854 0,07670834 ! lipid digestion GO:0044241 6 6 0,000 0,02588854 0,07658521 ! asymmetric protein localization GO:0008105 6 6 0,000 0,02588854 0,07646248 ! retrograde transport, endosome to Golgi GO:0042147 6 6 0,000 0,02588854 0,07634014 ! phagocytosis, engulfment GO:0006911 6 6 0,000 0,02588854 0,07621819 ! Rac protein signal transduction GO:0016601 6 6 0,000 0,02588854 0,07609663 ! regulation of vascular permeability GO:0043114 6 6 0,000 0,02588854 0,07597546 ! regulation of calcium ion transport into cytosol GO:0010522 6 6 0,000 0,02588854 0,07585467 ! ruffle organization GO:0031529 6 6 0,000 0,02588854 0,07573427 ! preassembly of GPI anchor in ER membrane GO:0016254 6 6 0,000 0,02588854 0,07561424 ! retinoic acid metabolic process GO:0042573 6 6 0,000 0,02588854 0,0754946 ! neutral amino acid transport GO:0015804 6 6 0,000 0,02588854 0,07537534 ! L-amino acid transport GO:0015807 6 6 0,000 0,02588854 0,07525645 ! bone mineralization GO:0030282 6 6 0,000 0,02588854 0,07513793 GO:0031214|biomineral formation, ! rRNA modification GO:0000154 6 6 0,000 0,02588854 0,07501979 ! negative regulation of ossification GO:0030279 6 6 0,000 0,02588854 0,07490202 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 6 6 0,000 0,02588854 0,07478462 GO:0002717|positive regulation of natural killer cell mediated immunity, GO:0002715|regulation of natural killer cell mediated immunity, GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of bone resorption GO:0045124 6 6 0,000 0,02588854 0,07466759 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 7 6 0,000 0,02588854 0,07455092 ! purine base biosynthetic process GO:0009113 6 6 0,000 0,02588854 0,07443462 ! regulation of phagocytosis GO:0050764 6 6 0,000 0,02588854 0,07431867 ! regulation of organ growth GO:0046620 6 6 0,000 0,02588854 0,07420309 ! regulation of circadian rhythm GO:0042752 6 6 0,000 0,02588854 0,07408787 ! positive regulation of T cell mediated immunity GO:0002711 6 6 0,000 0,02588854 0,07397301 ! response to dsRNA GO:0043331 6 6 0,000 0,02588854 0,0738585 ! DNA unwinding during replication GO:0006268 6 6 0,000 0,02588854 0,07374434 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 6 6 0,000 0,02588854 0,07363054 GO:0009147|pyrimidine nucleoside triphosphate metabolic process, ! genitalia development GO:0048806 6 6 0,000 0,02588854 0,07351709 ! sphingomyelin metabolic process GO:0006684 6 6 0,000 0,02588854 0,07340398 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 6 6 0,000 0,02588854 0,07329123 ! positive regulation of B cell differentiation GO:0045579 6 6 0,000 0,02588854 0,07317882 ! multicellular organismal aging GO:0010259 6 6 0,000 0,02588854 0,07306675 ! regulation of focal adhesion formation GO:0051893 7 6 0,000 0,02588854 0,07295503 ! respiratory chain complex IV assembly GO:0008535 6 6 0,000 0,02588854 0,07284365 ! erythrocyte development GO:0048821 6 6 0,000 0,02588854 0,0727326 ! renal water homeostasis GO:0003091 6 6 0,000 0,02588854 0,0726219 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 6 6 0,000 0,02588854 0,07251153 GO:0043372|positive regulation of CD4-positive, alpha beta T cell differentiation, ! ribosomal large subunit biogenesis GO:0042273 6 6 0,000 0,02588854 0,0724015 ! regulation of Rho GTPase activity GO:0032319 6 6 0,000 0,02588854 0,0722918 ! ribosome assembly GO:0042255 6 6 0,000 0,02588854 0,07218243 ! positive regulation of Ras GTPase activity GO:0032320 6 6 0,000 0,02588854 0,0720734 ! diencephalon development GO:0021536 6 6 0,000 0,02588854 0,07196469 ! fucose catabolic process GO:0019317 6 6 0,000 0,02588854 0,07185631 GO:0042355|L-fucose catabolic process, ! nitric oxide metabolic process GO:0046209 6 6 0,000 0,02588854 0,07174825 GO:0006809|nitric oxide biosynthetic process, ! protein sumoylation GO:0016925 6 6 0,000 0,02588854 0,07164052 ! regulation of lipid transport GO:0032368 6 6 0,000 0,02588854 0,07153312 ! regulation of cell division GO:0051302 6 6 0,000 0,02588854 0,07142603 ! positive regulation of interleukin-1 secretion GO:0050716 6 6 0,000 0,02588854 0,07131926 ! cellular metabolic compound salvage GO:0043094 6 6 0,000 0,02588854 0,07121282 ! regulation of T-helper 2 type immune response GO:0002828 6 6 0,000 0,02588854 0,07110669 ! salivary gland morphogenesis GO:0007435 6 6 0,000 0,02588854 0,07100088 ! neuroblast proliferation GO:0007405 6 6 0,000 0,02588854 0,07089538 ! regulation of interleukin-1 beta secretion GO:0050706 6 6 0,000 0,02588854 0,07079019 ! nitric oxide mediated signal transduction GO:0007263 6 6 0,000 0,02588854 0,07068532 ! regulation of glucose transport GO:0010827 6 6 0,000 0,02588854 0,07058075 GO:0046324|regulation of glucose import, ! intestinal absorption GO:0050892 6 6 0,000 0,02588854 0,0704765 ! methionine biosynthetic process GO:0009086 6 6 0,000 0,02588854 0,07037255 ! glutamine family amino acid biosynthetic process GO:0009084 6 6 0,000 0,02588854 0,07026891 ! serine family amino acid biosynthetic process GO:0009070 6 6 0,000 0,02588854 0,07016557 ! thymus development GO:0048538 6 6 0,000 0,02588854 0,07006254 ! lymph node development GO:0048535 6 6 0,000 0,02588854 0,06995981 ! organic cation transport GO:0015695 6 6 0,000 0,02588854 0,06985738 ! negative regulation of BMP signaling pathway GO:0030514 6 6 0,000 0,02588854 0,06975525 ! regulation of RNA splicing GO:0043484 6 6 0,000 0,02588854 0,06965341 ! positive regulation of JNK cascade GO:0046330 7 6 0,000 0,02588854 0,06955188 ! sperm-egg recognition GO:0035036 7 6 0,000 0,02588854 0,06945064 GO:0007339|binding of sperm to zona pellucida, ! germ cell migration GO:0008354 6 6 0,000 0,02588854 0,06934969 ! establishment or maintenance of apical/basal cell polarity GO:0035088 6 6 0,000 0,02588854 0,06924904 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 6 6 0,000 0,02588854 0,06914868 ! alditol metabolic process GO:0019400 6 6 0,000 0,02588854 0,06904861 ! regulation of synaptic transmission, GABAergic GO:0032228 6 6 0,000 0,02588854 0,06894883 ! regulation of amino acid transport GO:0051955 6 6 0,000 0,02588854 0,06884933 ! maternal placenta development GO:0001893 6 6 0,000 0,02588854 0,06875013 ! negative regulation of immune effector process GO:0002698 6 6 0,000 0,02588854 0,06865121 ! dephosphorylation GO:0016311 60 59 1,000 0,02696674 0,07140761 ! protein localization in organelle GO:0033365 59 59 1,000 0,02696674 0,07130516 ! regulation of protein amino acid phosphorylation GO:0001932 62 61 1,000 0,02868809 0,07574807 ! purine ribonucleoside triphosphate metabolic process GO:0009205 62 62 1,000 0,02956505 0,07795192 ! protein import GO:0017038 62 62 1,000 0,02956505 0,07784056 ! regulation of lymphocyte activation GO:0051249 62 62 1,000 0,02956505 0,07772952 ! respiratory burst GO:0045730 7 7 0,000 0,03013983 0,07912779 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 7 7 0,000 0,03013983 0,07901523 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 7 7 0,000 0,03013983 0,078903 ! positive regulation of blood pressure GO:0045777 7 7 0,000 0,03013983 0,07879108 ! pteridine and derivative biosynthetic process GO:0042559 7 7 0,000 0,03013983 0,07867947 ! regulation of chemokine production GO:0032642 7 7 0,000 0,03013983 0,07856819 ! double-strand break repair via homologous recombination GO:0000724 7 7 0,000 0,03013983 0,07845722 GO:0000725|recombinational repair, ! positive regulation of GTPase activity GO:0043547 7 7 0,000 0,03013983 0,07834656 ! SMAD protein nuclear translocation GO:0007184 7 7 0,000 0,03013983 0,07823621 ! cellular protein complex disassembly GO:0043624 8 7 0,000 0,03013983 0,07812617 GO:0043241|protein complex disassembly, ! hair follicle morphogenesis GO:0031069 7 7 0,000 0,03013983 0,07801645 ! gene silencing by RNA GO:0031047 7 7 0,000 0,03013983 0,07790703 ! regulation of receptor-mediated endocytosis GO:0048259 7 7 0,000 0,03013983 0,07779791 ! oxaloacetate metabolic process GO:0006107 7 7 0,000 0,03013983 0,0776891 ! regulation of neurotransmitter transport GO:0051588 7 7 0,000 0,03013983 0,0775806 ! axis specification GO:0009798 7 7 0,000 0,03013983 0,0774724 ! negative regulation of muscle cell differentiation GO:0051148 7 7 0,000 0,03013983 0,0773645 ! visual behavior GO:0007632 7 7 0,000 0,03013983 0,0772569 GO:0008542|visual learning, ! startle response GO:0001964 7 7 0,000 0,03013983 0,0771496 ! amyloid precursor protein metabolic process GO:0042982 7 7 0,000 0,03013983 0,07704259 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 8 7 0,000 0,03013983 0,07693589 ! positive regulation of lipid metabolic process GO:0045834 7 7 0,000 0,03013983 0,07682947 ! negative regulation of lipid metabolic process GO:0045833 7 7 0,000 0,03013983 0,07672336 ! regulation of interferon-gamma biosynthetic process GO:0045072 7 7 0,000 0,03013983 0,07661753 ! endothelial cell differentiation GO:0045446 7 7 0,000 0,03013983 0,076512 ! negative regulation of striated muscle development GO:0045843 7 7 0,000 0,03013983 0,07640675 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 7 7 0,000 0,03013983 0,0763018 ! digestive system development GO:0055123 7 7 0,000 0,03013983 0,07619713 GO:0048546|digestive tract morphogenesis, GO:0048547|gut morphogenesis, ! hemoglobin metabolic process GO:0020027 7 7 0,000 0,03013983 0,07609275 ! regulation of exit from mitosis GO:0007096 7 7 0,000 0,03013983 0,07598866 ! protein targeting to ER GO:0045047 8 7 0,000 0,03013983 0,07588485 ! cell differentiation in spinal cord GO:0021515 7 7 0,000 0,03013983 0,07578132 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 7 7 0,000 0,03013983 0,07567808 ! endoderm development GO:0007492 7 7 0,000 0,03013983 0,07557511 ! regulation of defense response to virus GO:0050688 7 7 0,000 0,03013983 0,07547243 ! glycolipid biosynthetic process GO:0009247 7 7 0,000 0,03013983 0,07537003 GO:0006688|glycosphingolipid biosynthetic process, ! response to hexose stimulus GO:0009746 7 7 0,000 0,03013983 0,0752679 GO:0034284|response to monosaccharide stimulus, GO:0009749|response to glucose stimulus, ! membrane protein ectodomain proteolysis GO:0006509 7 7 0,000 0,03013983 0,07516605 GO:0033619|membrane protein proteolysis, ! positive regulation of survival gene product expression GO:0045885 7 7 0,000 0,03013983 0,07506447 ! regulation of skeletal muscle fiber development GO:0048742 7 7 0,000 0,03013983 0,07496317 ! cardiac muscle tissue development GO:0048738 7 7 0,000 0,03013983 0,07486214 ! nucleotide-sugar metabolic process GO:0009225 7 7 0,000 0,03013983 0,07476139 ! complement activation, alternative pathway GO:0006957 7 7 0,000 0,03013983 0,0746609 ! arachidonic acid secretion GO:0050482 7 7 0,000 0,03013983 0,07456068 GO:0032309|icosanoid secretion, ! polyamine biosynthetic process GO:0006596 7 7 0,000 0,03013983 0,07446074 ! UV protection GO:0009650 7 7 0,000 0,03013983 0,07436106 ! DNA integration GO:0015074 7 7 0,000 0,03013983 0,07426164 ! myofibril assembly GO:0030239 7 7 0,000 0,03013983 0,0741625 GO:0055002|striated muscle cell development, ! positive regulation of muscle contraction GO:0045933 7 7 0,000 0,03013983 0,07406361 ! negative regulation of muscle contraction GO:0045932 7 7 0,000 0,03013983 0,07396499 ! chondroitin sulfate biosynthetic process GO:0030206 7 7 0,000 0,03013983 0,07386663 GO:0030204|chondroitin sulfate metabolic process, ! regulation of exocytosis GO:0017157 8 7 0,000 0,03013983 0,07376854 ! phosphatidylcholine biosynthetic process GO:0006656 7 7 0,000 0,03013983 0,0736707 ! heparan sulfate proteoglycan metabolic process GO:0030201 7 7 0,000 0,03013983 0,07357312 GO:0015012|heparan sulfate proteoglycan biosynthetic process, ! stem cell development GO:0048864 7 7 0,000 0,03013983 0,07347581 GO:0019827|stem cell maintenance, ! alpha-beta T cell differentiation GO:0046632 7 7 0,000 0,03013983 0,07337874 ! negative regulation of myeloid leukocyte differentiation GO:0002762 7 7 0,000 0,03013983 0,07328194 ! NLS-bearing substrate import into nucleus GO:0006607 7 7 0,000 0,03013983 0,07318539 ! axon cargo transport GO:0008088 7 7 0,000 0,03013983 0,07308909 ! eating behavior GO:0042755 7 7 0,000 0,03013983 0,07299305 ! RNA-dependent DNA replication GO:0006278 7 7 0,000 0,03013983 0,07289726 ! regulation of interleukin-8 production GO:0032677 7 7 0,000 0,03013983 0,07280172 ! ribosomal small subunit biogenesis GO:0042274 7 7 0,000 0,03013983 0,07270643 ! cranial nerve development GO:0021545 7 7 0,000 0,03013983 0,07261138 ! protein import into peroxisome matrix GO:0016558 7 7 0,000 0,03013983 0,07251659 ! induction of an organ GO:0001759 7 7 0,000 0,03013983 0,07242205 ! leukocyte activation during immune response GO:0002366 7 7 0,000 0,03013983 0,07232775 GO:0002263|cell activation during immune response, ! response to estradiol stimulus GO:0032355 7 7 0,000 0,03013983 0,07223369 ! autonomic nervous system development GO:0048483 7 7 0,000 0,03013983 0,07213988 ! intracellular lipid transport GO:0032365 7 7 0,000 0,03013983 0,07204632 ! detection of chemical stimulus GO:0009593 8 7 0,000 0,03013983 0,07195299 ! platelet activation GO:0030168 8 7 0,000 0,03013983 0,07185991 ! negative regulation of cytokine secretion GO:0050710 7 7 0,000 0,03013983 0,07176707 ! regulation of interleukin-1 secretion GO:0050704 7 7 0,000 0,03013983 0,07167446 ! natural killer cell activation GO:0030101 7 7 0,000 0,03013983 0,0715821 ! NADP metabolic process GO:0006739 7 7 0,000 0,03013983 0,07148997 ! neuromuscular synaptic transmission GO:0007274 7 7 0,000 0,03013983 0,07139808 ! synaptic transmission, cholinergic GO:0007271 7 7 0,000 0,03013983 0,07130643 ! ubiquinone metabolic process GO:0006743 7 7 0,000 0,03013983 0,07121501 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, GO:0042375|quinone cofactor metabolic process, ! regulation of macrophage differentiation GO:0045649 8 7 0,000 0,03013983 0,07112383 ! positive regulation of acute inflammatory response GO:0002675 7 7 0,000 0,03013983 0,07103288 ! regulation of osteoclast differentiation GO:0045670 7 7 0,000 0,03013983 0,07094216 ! negative regulation of cell-substrate adhesion GO:0010812 8 7 0,000 0,03013983 0,07085167 GO:0001953|negative regulation of cell-matrix adhesion, ! multicellular organismal water homeostasis GO:0050891 7 7 0,000 0,03013983 0,07076141 ! regulation of ATPase activity GO:0043462 7 7 0,000 0,03013983 0,07067139 ! cell-cell recognition GO:0009988 8 7 0,000 0,03013983 0,07058159 ! hormone catabolic process GO:0042447 7 7 0,000 0,03013983 0,07049202 ! dopamine metabolic process GO:0042417 7 7 0,000 0,03013983 0,07040267 ! cAMP biosynthetic process GO:0006171 7 7 0,000 0,03013983 0,07031356 ! oxygen transport GO:0015671 7 7 0,000 0,03013983 0,07022466 ! pyridine nucleotide biosynthetic process GO:0019363 7 7 0,000 0,03013983 0,070136 ! regulation of mRNA stability GO:0043488 7 7 0,000 0,03013983 0,07004755 ! biogenic amine catabolic process GO:0042402 7 7 0,000 0,03013983 0,06995933 ! regulation of axon extension GO:0030516 7 7 0,000 0,03013983 0,06987133 ! cell killing GO:0001906 7 7 0,000 0,03013983 0,06978355 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 7 7 0,000 0,03013983 0,069696 ! adult feeding behavior GO:0008343 7 7 0,000 0,03013983 0,06960866 ! pyrimidine nucleotide catabolic process GO:0006244 7 7 0,000 0,03013983 0,06952154 ! positive regulation of protein polymerization GO:0032273 7 7 0,000 0,03013983 0,06943464 ! T cell receptor signaling pathway GO:0050852 7 7 0,000 0,03013983 0,06934795 ! response to cold GO:0009409 7 7 0,000 0,03013983 0,06926148 ! regulation of secretion GO:0051046 65 63 1,000 0,03045273 0,06989337 ! negative regulation of cellular component organization GO:0051129 65 63 1,000 0,03045273 0,06980644 ! ribonucleoside triphosphate metabolic process GO:0009199 63 63 1,000 0,03045273 0,06971972 ! purine nucleoside triphosphate metabolic process GO:0009144 63 63 1,000 0,03045273 0,06963322 ! glycerolipid metabolic process GO:0046486 65 64 1,000 0,03135102 0,07159842 ! angiogenesis GO:0001525 65 64 1,000 0,03135102 0,07150981 ! positive regulation of protein metabolic process GO:0051247 64 64 1,000 0,03135102 0,07142141 ! regulation of hormone levels GO:0010817 66 65 1,000 0,03225982 0,07340104 ! nucleoside triphosphate metabolic process GO:0009141 66 66 1,000 0,03317902 0,07539943 ! polysaccharide metabolic process GO:0005976 69 66 1,000 0,03317902 0,07530657 ! negative regulation of protein metabolic process GO:0051248 66 66 1,000 0,03317902 0,07521394 ! regulation of skeletal muscle tissue development GO:0048641 8 8 0,000 0,03437318 0,07782527 ! negative regulation of muscle development GO:0048635 8 8 0,000 0,03437318 0,07772978 ! very-long-chain fatty acid metabolic process GO:0000038 8 8 0,000 0,03437318 0,07763452 ! positive regulation of translation GO:0045727 8 8 0,000 0,03437318 0,0775395 ! positive regulation of cell killing GO:0031343 8 8 0,000 0,03437318 0,07744471 ! superoxide anion generation GO:0042554 8 8 0,000 0,03437318 0,07735015 ! sulfur amino acid biosynthetic process GO:0000097 8 8 0,000 0,03437318 0,07725582 ! cGMP metabolic process GO:0046068 8 8 0,000 0,03437318 0,07716172 GO:0006182|cGMP biosynthetic process, ! thyroid gland development GO:0030878 8 8 0,000 0,03437318 0,07706785 ! 'de novo' protein folding GO:0006458 8 8 0,000 0,03437318 0,07697421 ! dicarboxylic acid transport GO:0006835 8 8 0,000 0,03437318 0,07688079 ! phosphoinositide phosphorylation GO:0046854 8 8 0,000 0,03437318 0,0767876 ! negative regulation of bone remodeling GO:0046851 8 8 0,000 0,03437318 0,07669464 ! embryonic hindlimb morphogenesis GO:0035116 8 8 0,000 0,03437318 0,0766019 ! zinc ion transport GO:0006829 8 8 0,000 0,03437318 0,07650939 ! embryonic forelimb morphogenesis GO:0035115 8 8 0,000 0,03437318 0,07641709 ! folic acid and derivative biosynthetic process GO:0009396 8 8 0,000 0,03437318 0,07632503 ! regulation of neuronal synaptic plasticity GO:0048168 8 8 0,000 0,03437318 0,07623318 ! cardiac muscle contraction GO:0060048 8 8 0,000 0,03437318 0,07614155 ! lipid localization GO:0010876 8 8 0,000 0,03437318 0,07605015 GO:0019915|lipid storage, ! response to pain GO:0048265 8 8 0,000 0,03437318 0,07595896 ! response to cAMP GO:0051591 8 8 0,000 0,03437318 0,07586799 ! COPI coating of Golgi vesicle GO:0048205 8 8 0,000 0,03437318 0,07577724 GO:0048200|Golgi transport vesicle coating, ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 8 0,000 0,03437318 0,0756867 ! negative regulation of transcription factor import into nucleus GO:0042992 8 8 0,000 0,03437318 0,07559639 ! negative regulation of ion transport GO:0043271 8 8 0,000 0,03437318 0,07550628 ! regulation of response to extracellular stimulus GO:0032104 8 8 0,000 0,03437318 0,07541639 GO:0032107|regulation of response to nutrient levels, ! adult walking behavior GO:0007628 8 8 0,000 0,03437318 0,07532672 ! sensory perception of taste GO:0050909 8 8 0,000 0,03437318 0,07523726 ! organelle fusion GO:0048284 8 8 0,000 0,03437318 0,07514801 ! pancreas development GO:0031016 8 8 0,000 0,03437318 0,07505897 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 8 8 0,000 0,03437318 0,07497014 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! T cell selection GO:0045058 8 8 0,000 0,03437318 0,07488153 ! negative regulation of proteolysis GO:0045861 8 8 0,000 0,03437318 0,07479312 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 8 8 0,000 0,03437318 0,07470492 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 8 8 0,000 0,03437318 0,07461693 ! sperm motility GO:0030317 8 8 0,000 0,03437318 0,07452914 ! regulation of striated muscle contraction GO:0006942 8 8 0,000 0,03437318 0,07444156 ! DNA duplex unwinding GO:0032508 8 8 0,000 0,03437318 0,07435419 GO:0032392|DNA geometric change, ! glycine metabolic process GO:0006544 8 8 0,000 0,03437318 0,07426702 ! negative regulation of microtubule depolymerization GO:0007026 8 8 0,000 0,03437318 0,07418006 GO:0031114|regulation of microtubule depolymerization, ! phosphagen metabolic process GO:0006599 8 8 0,000 0,03437318 0,0740933 GO:0006600|creatine metabolic process, ! polyamine metabolic process GO:0006595 8 8 0,000 0,03437318 0,07400674 ! Golgi organization GO:0007030 8 8 0,000 0,03437318 0,07392039 ! cell-cell junction assembly GO:0007043 8 8 0,000 0,03437318 0,07383423 ! regulation of stress fiber formation GO:0051492 9 8 0,000 0,03437318 0,07374828 ! positive regulation of endothelial cell migration GO:0010595 8 8 0,000 0,03437318 0,07366252 ! fructose metabolic process GO:0006000 8 8 0,000 0,03437318 0,07357697 ! mannose metabolic process GO:0006013 9 8 0,000 0,03437318 0,07349161 ! NAD metabolic process GO:0019674 8 8 0,000 0,03437318 0,07340646 ! negative regulation of mitotic cell cycle GO:0045930 9 8 0,000 0,03437318 0,07332149 ! plasma membrane fusion GO:0045026 8 8 0,000 0,03437318 0,07323673 ! response to fungus GO:0009620 8 8 0,000 0,03437318 0,07315216 ! stem cell differentiation GO:0048863 8 8 0,000 0,03437318 0,07306779 ! alpha-beta T cell activation GO:0046631 8 8 0,000 0,03437318 0,07298361 ! positive regulation of myeloid leukocyte differentiation GO:0002763 9 8 0,000 0,03437318 0,07289962 ! embryonic digit morphogenesis GO:0042733 8 8 0,000 0,03437318 0,07281583 ! regulation of cytokine production during immune response GO:0002718 8 8 0,000 0,03437318 0,07273223 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 0,03437318 0,07264882 ! regulation of vasodilation GO:0042312 8 8 0,000 0,03437318 0,0725656 ! vasoconstriction GO:0042310 8 8 0,000 0,03437318 0,07248258 ! regulation of T cell mediated immunity GO:0002709 8 8 0,000 0,03437318 0,07239974 ! muscle cell development GO:0055001 8 8 0,000 0,03437318 0,07231709 ! regulation of fatty acid metabolic process GO:0019217 8 8 0,000 0,03437318 0,07223463 ! sensory perception of pain GO:0019233 8 8 0,000 0,03437318 0,07215236 ! gastrulation with mouth forming second GO:0001702 8 8 0,000 0,03437318 0,07207027 ! immunoglobulin production during immune response GO:0002381 8 8 0,000 0,03437318 0,07198838 GO:0002208|somatic diversification of immunoglobulins during immune response, GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! mRNA cleavage GO:0006379 8 8 0,000 0,03437318 0,07190666 ! chromatin silencing GO:0006342 8 8 0,000 0,03437318 0,07182514 ! tissue regeneration GO:0042246 8 8 0,000 0,03437318 0,07174379 ! salivary gland development GO:0007431 8 8 0,000 0,03437318 0,07166264 ! negative regulation of blood coagulation GO:0030195 9 8 0,000 0,03437318 0,07158166 ! T cell homeostasis GO:0043029 8 8 0,000 0,03437318 0,07150087 ! peptide biosynthetic process GO:0043043 9 8 0,000 0,03437318 0,07142026 ! water homeostasis GO:0030104 8 8 0,000 0,03437318 0,07133983 ! cofactor transport GO:0051181 8 8 0,000 0,03437318 0,07125958 ! regulation of acute inflammatory response GO:0002673 8 8 0,000 0,03437318 0,07117952 ! acid secretion GO:0046717 8 8 0,000 0,03437318 0,07109963 ! positive regulation of leukocyte migration GO:0002687 8 8 0,000 0,03437318 0,07101992 ! C21-steroid hormone biosynthetic process GO:0006700 8 8 0,000 0,03437318 0,07094039 ! protein-chromophore linkage GO:0018298 9 8 0,000 0,03437318 0,07086104 ! regulation of immunoglobulin production GO:0002637 8 8 0,000 0,03437318 0,07078187 ! branched chain family amino acid metabolic process GO:0009081 8 8 0,000 0,03437318 0,07070287 ! catecholamine biosynthetic process GO:0042423 8 8 0,000 0,03437318 0,07062405 ! regulation of RNA stability GO:0043487 8 8 0,000 0,03437318 0,0705454 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 8 8 0,000 0,03437318 0,07046693 ! aromatic compound biosynthetic process GO:0019438 8 8 0,000 0,03437318 0,07038863 ! regulation of organic acid transport GO:0032890 8 8 0,000 0,03437318 0,07031051 ! positive regulation of calcium ion transport GO:0051928 8 8 0,000 0,03437318 0,07023256 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 8 8 0,000 0,03437318 0,07015478 ! regulation of multi-organism process GO:0043900 8 8 0,000 0,03437318 0,07007718 ! positive regulation of amine transport GO:0051954 8 8 0,000 0,03437318 0,06999975 ! developmental induction GO:0031128 8 8 0,000 0,03437318 0,06992248 GO:0045168|cell-cell signaling involved in cell fate specification, ! peptide hormone secretion GO:0030072 8 8 0,000 0,03437318 0,06984539 ! positive regulation of calcium-mediated signaling GO:0050850 8 8 0,000 0,03437318 0,06976847 ! actin filament polymerization GO:0030041 9 8 0,000 0,03437318 0,06969172 ! peptide hormone processing GO:0016486 8 8 0,000 0,03437318 0,06961513 ! positive regulation of synaptic transmission GO:0050806 8 8 0,000 0,03437318 0,06953872 ! regulation of steroid biosynthetic process GO:0050810 8 8 0,000 0,03437318 0,06946247 ! sensory perception of sound GO:0007605 71 69 1,000 0,03599808 0,07266643 GO:0050954|sensory perception of mechanical stimulus, ! response to nutrient levels GO:0031667 69 69 1,000 0,03599808 0,07258693 ! regulation of leukocyte activation GO:0002694 69 69 1,000 0,03599808 0,0725076 ! wound healing GO:0042060 74 70 1,000 0,0369579 0,07435963 ! growth GO:0040007 70 70 1,000 0,0369579 0,07427854 ! regulation of cell activation GO:0050865 71 71 1,000 0,03792764 0,07614449 ! lactation GO:0007595 10 9 0,000 0,03858866 0,07738728 ! embryonic pattern specification GO:0009880 10 9 0,000 0,03858866 0,07730316 ! positive regulation of cell projection organization GO:0031346 9 9 0,000 0,03858866 0,07721923 ! regulation of membrane protein ectodomain proteolysis GO:0051043 9 9 0,000 0,03858866 0,07713547 ! positive regulation of protein complex assembly GO:0031334 9 9 0,000 0,03858866 0,0770519 ! cortical actin cytoskeleton organization GO:0030866 10 9 0,000 0,03858866 0,07696851 ! negative regulation of cell cycle process GO:0010948 9 9 0,000 0,03858866 0,07688531 ! viral genome replication GO:0019079 9 9 0,000 0,03858866 0,07680228 ! phospholipid catabolic process GO:0009395 9 9 0,000 0,03858866 0,07671943 ! copper ion transport GO:0006825 9 9 0,000 0,03858866 0,07663675 ! lipid phosphorylation GO:0046834 9 9 0,000 0,03858866 0,07655426 ! aminoglycan catabolic process GO:0006026 9 9 0,000 0,03858866 0,07647194 ! Golgi vesicle budding GO:0048194 9 9 0,000 0,03858866 0,0763898 ! regulation of cell-cell adhesion GO:0022407 9 9 0,000 0,03858866 0,07630784 ! RNA polyadenylation GO:0043631 9 9 0,000 0,03858866 0,07622605 GO:0006378|mRNA polyadenylation, ! gamma-aminobutyric acid signaling pathway GO:0007214 9 9 0,000 0,03858866 0,07614444 ! regulation of postsynaptic membrane potential GO:0060078 9 9 0,000 0,03858866 0,076063 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 9 9 0,000 0,03858866 0,07598174 ! negative regulation of cytokine biosynthetic process GO:0042036 9 9 0,000 0,03858866 0,07590065 ! phospholipid efflux GO:0033700 9 9 0,000 0,03858866 0,07581973 ! response to alkaloid GO:0043279 10 9 0,000 0,03858866 0,07573899 ! cytokine biosynthetic process GO:0042089 9 9 0,000 0,03858866 0,07565841 GO:0042107|cytokine metabolic process, ! positive regulation of endothelial cell proliferation GO:0001938 9 9 0,000 0,03858866 0,07557801 ! negative regulation of gene expression, epigenetic GO:0045814 9 9 0,000 0,03858866 0,07549778 ! regulation of interleukin-2 biosynthetic process GO:0045076 9 9 0,000 0,03858866 0,07541772 ! response to ethanol GO:0045471 9 9 0,000 0,03858866 0,07533783 ! platelet-derived growth factor receptor signaling pathway GO:0048008 9 9 0,000 0,03858866 0,0752581 ! pyrimidine ribonucleotide metabolic process GO:0009218 9 9 0,000 0,03858866 0,07517855 ! activation of pro-apoptotic gene products GO:0008633 9 9 0,000 0,03858866 0,07509916 ! methionine metabolic process GO:0006555 9 9 0,000 0,03858866 0,07501994 ! glutamine metabolic process GO:0006541 9 9 0,000 0,03858866 0,07494089 ! cerebral cortex development GO:0021987 9 9 0,000 0,03858866 0,07486201 ! response to osmotic stress GO:0006970 9 9 0,000 0,03858866 0,07478329 ! pigmentation during development GO:0048066 9 9 0,000 0,03858866 0,07470473 ! reverse cholesterol transport GO:0043691 9 9 0,000 0,03858866 0,07462635 ! central nervous system neuron development GO:0021954 10 9 0,000 0,03858866 0,07454812 ! pyrimidine ribonucleoside metabolic process GO:0046131 9 9 0,000 0,03858866 0,07447006 ! nucleobase biosynthetic process GO:0046112 9 9 0,000 0,03858866 0,07439216 ! neurotransmitter metabolic process GO:0042133 11 9 0,000 0,03858866 0,07431443 ! branching involved in ureteric bud morphogenesis GO:0001658 9 9 0,000 0,03858866 0,07423686 GO:0060675|ureteric bud morphogenesis, ! L-glutamate transport GO:0015813 9 9 0,000 0,03858866 0,07415944 GO:0015800|acidic amino acid transport, ! peptide secretion GO:0002790 9 9 0,000 0,03858866 0,0740822 ! regulation of dephosphorylation GO:0035303 9 9 0,000 0,03858866 0,07400511 ! cotranslational protein targeting to membrane GO:0006613 10 9 0,000 0,03858866 0,07392818 ! positive regulation of alpha-beta T cell differentiation GO:0046638 9 9 0,000 0,03858866 0,07385141 ! ventricular cardiac muscle morphogenesis GO:0055010 9 9 0,000 0,03858866 0,0737748 ! behavioral interaction between organisms GO:0051705 9 9 0,000 0,03858866 0,07369835 ! negative regulation of protein import into nucleus GO:0042308 9 9 0,000 0,03858866 0,07362206 ! DNA replication initiation GO:0006270 9 9 0,000 0,03858866 0,07354592 ! prostaglandin metabolic process GO:0006693 9 9 0,000 0,03858866 0,07346995 GO:0006692|prostanoid metabolic process, ! T cell differentiation in the thymus GO:0033077 9 9 0,000 0,03858866 0,07339413 ! DNA fragmentation involved in apoptosis GO:0006309 9 9 0,000 0,03858866 0,07331846 ! regulation of immunoglobulin mediated immune response GO:0002889 9 9 0,000 0,03858866 0,07324295 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 10 9 0,000 0,03858866 0,0731676 ! positive regulation of oxidoreductase activity GO:0051353 9 9 0,000 0,03858866 0,0730924 ! positive regulation of cytokine secretion GO:0050715 9 9 0,000 0,03858866 0,07301736 ! negative regulation of inflammatory response GO:0050728 9 9 0,000 0,03858866 0,07294247 ! negative regulation of tissue remodeling GO:0034104 9 9 0,000 0,03858866 0,07286773 ! negative regulation of protein secretion GO:0050709 9 9 0,000 0,03858866 0,07279315 ! regulation of leukocyte migration GO:0002685 9 9 0,000 0,03858866 0,07271872 ! positive regulation of transmission of nerve impulse GO:0051971 9 9 0,000 0,03858866 0,07264444 ! collagen catabolic process GO:0030574 9 9 0,000 0,03858866 0,07257031 ! aromatic amino acid family catabolic process GO:0009074 9 9 0,000 0,03858866 0,07249634 ! purine base metabolic process GO:0006144 9 9 0,000 0,03858866 0,07242251 ! gas transport GO:0015669 9 9 0,000 0,03858866 0,07234884 ! cholesterol efflux GO:0033344 9 9 0,000 0,03858866 0,07227531 ! regulation of leukocyte mediated cytotoxicity GO:0001910 9 9 0,000 0,03858866 0,07220194 ! estrogen receptor signaling pathway GO:0030520 9 9 0,000 0,03858866 0,07212871 ! somatic recombination of immunoglobulin gene segments GO:0016447 9 9 0,000 0,03858866 0,07205563 ! regulation of actin filament bundle formation GO:0032231 10 9 0,000 0,03858866 0,0719827 ! regulation of blood vessel endothelial cell migration GO:0043535 9 9 0,000 0,03858866 0,07190992 ! defense response to virus GO:0051607 9 9 0,000 0,03858866 0,07183728 ! regulation of calcium-mediated signaling GO:0050848 9 9 0,000 0,03858866 0,07176479 ! actin filament-based movement GO:0030048 9 9 0,000 0,03858866 0,07169245 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 9 9 0,000 0,03858866 0,07162025 ! response to extracellular stimulus GO:0009991 72 72 1,000 0,03890719 0,07213878 ! coenzyme metabolic process GO:0006732 75 74 1,000 0,04089531 0,0757488 ! purine ribonucleotide metabolic process GO:0009150 75 75 1,000 0,0419037 0,07753867 ! protein import into nucleus, docking GO:0000059 10 10 0,000 0,04278636 0,07909253 ! regulation of protein ubiquitination GO:0031396 10 10 0,000 0,04278636 0,07901328 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 10 10 0,000 0,04278636 0,07893419 ! ER-associated protein catabolic process GO:0030433 10 10 0,000 0,04278636 0,07885525 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of cell killing GO:0031341 10 10 0,000 0,04278636 0,07877648 ! neuron maturation GO:0042551 10 10 0,000 0,04278636 0,07869786 ! pteridine and derivative metabolic process GO:0042558 10 10 0,000 0,04278636 0,0786194 ! positive regulation of anti-apoptosis GO:0045768 10 10 0,000 0,04278636 0,07854109 GO:0045767|regulation of anti-apoptosis, ! cortical cytoskeleton organization GO:0030865 11 10 0,000 0,04278636 0,07846294 ! regulation of lipid biosynthetic process GO:0046890 10 10 0,000 0,04278636 0,07838494 ! reciprocal meiotic recombination GO:0007131 10 10 0,000 0,04278636 0,0783071 ! hormone secretion GO:0046879 10 10 0,000 0,04278636 0,07822942 ! glucosamine metabolic process GO:0006041 10 10 0,000 0,04278636 0,07815189 GO:0006044|N-acetylglucosamine metabolic process, ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 10 10 0,000 0,04278636 0,07807451 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! inositol metabolic process GO:0006020 10 10 0,000 0,04278636 0,07799728 ! cAMP metabolic process GO:0046058 10 10 0,000 0,04278636 0,07792021 ! vesicle targeting, to, from or within Golgi GO:0048199 10 10 0,000 0,04278636 0,07784329 ! transcription from RNA polymerase III promoter GO:0006383 10 10 0,000 0,04278636 0,07776652 ! forelimb morphogenesis GO:0035136 10 10 0,000 0,04278636 0,0776899 ! glial cell development GO:0021782 10 10 0,000 0,04278636 0,07761344 ! phototransduction GO:0007602 11 10 0,000 0,04278636 0,07753712 ! calcium-independent cell-cell adhesion GO:0016338 10 10 0,000 0,04278636 0,07746096 ! auditory receptor cell differentiation GO:0042491 10 10 0,000 0,04278636 0,07738494 ! fat cell differentiation GO:0045444 10 10 0,000 0,04278636 0,07730907 ! myoblast differentiation GO:0045445 10 10 0,000 0,04278636 0,07723335 ! centrosome cycle GO:0007098 10 10 0,000 0,04278636 0,07715778 ! inactivation of MAPK activity GO:0000188 10 10 0,000 0,04278636 0,07708236 ! positive regulation of proteolysis GO:0045862 10 10 0,000 0,04278636 0,07700708 ! response to carbohydrate stimulus GO:0009743 10 10 0,000 0,04278636 0,07693195 ! regulation of survival gene product expression GO:0045884 10 10 0,000 0,04278636 0,07685697 ! induction of apoptosis via death domain receptors GO:0008625 10 10 0,000 0,04278636 0,07678214 ! epidermis morphogenesis GO:0048730 10 10 0,000 0,04278636 0,07670744 ! protein polyubiquitination GO:0000209 10 10 0,000 0,04278636 0,0766329 ! glutamate metabolic process GO:0006536 11 10 0,000 0,04278636 0,0765585 ! plasma membrane organization GO:0007009 10 10 0,000 0,04278636 0,07648424 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 10 10 0,000 0,04278636 0,07641013 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cell-substrate junction assembly GO:0007044 11 10 0,000 0,04278636 0,07633616 ! lysosomal transport GO:0007041 10 10 0,000 0,04278636 0,07626233 ! cellular response to unfolded protein GO:0034620 10 10 0,000 0,04278636 0,07618865 GO:0030968|endoplasmic reticulum unfolded protein response, ! central nervous system neuron differentiation GO:0021953 11 10 0,000 0,04278636 0,07611511 ! vesicle coating GO:0006901 10 10 0,000 0,04278636 0,07604171 ! exocrine system development GO:0035272 10 10 0,000 0,04278636 0,07596845 ! cell structure disassembly during apoptosis GO:0006921 10 10 0,000 0,04278636 0,07589534 ! embryo implantation GO:0007566 11 10 0,000 0,04278636 0,07582236 ! regulation of protein binding GO:0043393 11 10 0,000 0,04278636 0,07574952 ! protein targeting to peroxisome GO:0006625 10 10 0,000 0,04278636 0,07567683 ! protein targeting to mitochondrion GO:0006626 10 10 0,000 0,04278636 0,07560427 GO:0070585|protein localization in mitochondrion, ! regulation of alpha-beta T cell differentiation GO:0046637 10 10 0,000 0,04278636 0,07553185 ! intermediate filament cytoskeleton organization GO:0045104 10 10 0,000 0,04278636 0,07545957 ! protein export from nucleus GO:0006611 10 10 0,000 0,04278636 0,07538743 ! negative regulation of immune response GO:0050777 10 10 0,000 0,04278636 0,07531543 ! cytolysis GO:0019835 10 10 0,000 0,04278636 0,07524356 ! positive regulation of biomineral formation GO:0070169 10 10 0,000 0,04278636 0,07517183 GO:0030501|positive regulation of bone mineralization, ! mismatch repair GO:0006298 10 10 0,000 0,04278636 0,07510024 ! regulation of B cell differentiation GO:0045577 10 10 0,000 0,04278636 0,07502879 ! histone deacetylation GO:0016575 10 10 0,000 0,04278636 0,07495747 ! mRNA splice site selection GO:0006376 11 10 0,000 0,04278636 0,07488628 ! synaptic vesicle transport GO:0048489 11 10 0,000 0,04278636 0,07481523 ! gland morphogenesis GO:0022612 10 10 0,000 0,04278636 0,07474432 ! positive regulation of neurological system process GO:0031646 10 10 0,000 0,04278636 0,07467354 ! sphingolipid biosynthetic process GO:0030148 10 10 0,000 0,04278636 0,07460289 GO:0046467|membrane lipid biosynthetic process, ! sphingolipid catabolic process GO:0030149 10 10 0,000 0,04278636 0,07453238 GO:0046466|membrane lipid catabolic process, ! nerve-nerve synaptic transmission GO:0007270 10 10 0,000 0,04278636 0,074462 ! regulation of erythrocyte differentiation GO:0045646 10 10 0,000 0,04278636 0,07439175 ! regulation of epidermis development GO:0045682 10 10 0,000 0,04278636 0,07432163 ! folic acid and derivative metabolic process GO:0006760 10 10 0,000 0,04278636 0,07425165 ! negative regulation of neuron differentiation GO:0045665 10 10 0,000 0,04278636 0,0741818 ! aspartate family amino acid biosynthetic process GO:0009067 10 10 0,000 0,04278636 0,07411208 ! regulation of BMP signaling pathway GO:0030510 10 10 0,000 0,04278636 0,07404249 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 10 10 0,000 0,04278636 0,07397303 ! lymphocyte homeostasis GO:0002260 10 10 0,000 0,04278636 0,07390371 ! nerve development GO:0021675 10 10 0,000 0,04278636 0,07383451 ! epithelial to mesenchymal transition GO:0001837 10 10 0,000 0,04278636 0,07376544 ! gut development GO:0048565 10 10 0,000 0,04278636 0,0736965 ! embryonic organ morphogenesis GO:0048562 10 10 0,000 0,04278636 0,07362769 ! negative regulation of homeostatic process GO:0032845 10 10 0,000 0,04278636 0,07355901 ! mRNA 3'-end processing GO:0031124 10 10 0,000 0,04278636 0,07349045 ! antigen receptor-mediated signaling pathway GO:0050851 10 10 0,000 0,04278636 0,07342202 ! negative regulation of coagulation GO:0050819 11 10 0,000 0,04278636 0,07335372 ! regulation of protein modification process GO:0031399 79 78 1,000 0,04498501 0,07705146 ! positive regulation of protein kinase cascade GO:0010740 79 78 1,000 0,04498501 0,07697992 ! nuclear transport GO:0051169 79 79 1,000 0,04603051 0,07869595 GO:0006913|nucleocytoplasmic transport, ! protein secretion GO:0009306 11 11 0,000 0,04696633 0,08022145 ! oligosaccharide metabolic process GO:0009311 11 11 0,000 0,04696633 0,08014717 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 11 11 0,000 0,04696633 0,08007303 ! myeloid leukocyte differentiation GO:0002573 12 11 0,000 0,04696633 0,07999902 ! negative regulation of defense response GO:0031348 11 11 0,000 0,04696633 0,07992515 ! G1 phase of mitotic cell cycle GO:0000080 12 11 0,000 0,04696633 0,07985142 ! determination of bilateral symmetry GO:0009855 11 11 0,000 0,04696633 0,07977783 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! phosphatidylinositol metabolic process GO:0046488 11 11 0,000 0,04696633 0,07970437 ! cellular component assembly involved in morphogenesis GO:0010927 11 11 0,000 0,04696633 0,07963104 ! microtubule-based transport GO:0010970 11 11 0,000 0,04696633 0,07955785 ! endothelial cell migration GO:0043542 11 11 0,000 0,04696633 0,0794848 ! peroxisomal transport GO:0043574 11 11 0,000 0,04696633 0,07941187 ! protein amino acid methylation GO:0006479 11 11 0,000 0,04696633 0,07933909 GO:0008213|protein amino acid alkylation, ! heart contraction GO:0060047 11 11 0,000 0,04696633 0,07926643 GO:0003015|heart process, ! detection of light stimulus involved in sensory perception GO:0050962 12 11 0,000 0,04696633 0,07919391 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 11 11 0,000 0,04696633 0,07912152 ! T cell proliferation GO:0042098 11 11 0,000 0,04696633 0,07904926 ! negative regulation of endothelial cell proliferation GO:0001937 11 11 0,000 0,04696633 0,07897714 ! regulation of viral genome replication GO:0045069 11 11 0,000 0,04696633 0,07890514 ! spinal cord development GO:0021510 11 11 0,000 0,04696633 0,07883328 ! activation of MAPKK activity GO:0000186 12 11 0,000 0,04696633 0,07876155 ! smooth muscle contraction GO:0006939 11 11 0,000 0,04696633 0,07868995 ! cellular macromolecular complex disassembly GO:0034623 12 11 0,000 0,04696633 0,07861848 ! digestive system process GO:0022600 11 11 0,000 0,04696633 0,07854713 ! mitotic spindle organization GO:0007052 11 11 0,000 0,04696633 0,07847592 ! fucose metabolic process GO:0006004 11 11 0,000 0,04696633 0,07840484 ! membrane budding GO:0006900 11 11 0,000 0,04696633 0,07833388 ! apoptotic nuclear changes GO:0030262 11 11 0,000 0,04696633 0,07826306 ! monoamine transport GO:0015844 11 11 0,000 0,04696633 0,07819236 ! regulation of cellular ketone metabolic process GO:0010565 11 11 0,000 0,04696633 0,07812179 ! response to lipopolysaccharide GO:0032496 11 11 0,000 0,04696633 0,07805135 ! body fluid secretion GO:0007589 11 11 0,000 0,04696633 0,07798103 ! positive regulation of alpha-beta T cell activation GO:0046635 11 11 0,000 0,04696633 0,07791084 ! intermediate filament-based process GO:0045103 11 11 0,000 0,04696633 0,07784078 ! cardiac muscle tissue morphogenesis GO:0055008 11 11 0,000 0,04696633 0,07777084 GO:0060415|muscle tissue morphogenesis, ! membrane depolarization GO:0051899 11 11 0,000 0,04696633 0,07770103 ! regulation of interleukin-2 production GO:0032663 11 11 0,000 0,04696633 0,07763134 ! regulation of ARF GTPase activity GO:0032312 11 11 0,000 0,04696633 0,07756178 ! oogenesis GO:0048477 11 11 0,000 0,04696633 0,07749234 ! negative regulation of angiogenesis GO:0016525 11 11 0,000 0,04696633 0,07742303 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 11 11 0,000 0,04696633 0,07735384 ! vitamin transport GO:0051180 11 11 0,000 0,04696633 0,07728477 ! muscle maintenance GO:0046716 12 11 0,000 0,04696633 0,07721583 ! vitamin A metabolic process GO:0006776 11 11 0,000 0,04696633 0,07714701 ! steroid catabolic process GO:0006706 11 11 0,000 0,04696633 0,07707831 ! endocrine process GO:0050886 11 11 0,000 0,04696633 0,07700974 GO:0001990|regulation of systemic arterial blood pressure by hormone, ! aromatic amino acid family metabolic process GO:0009072 11 11 0,000 0,04696633 0,07694128 ! proximal/distal pattern formation GO:0009954 11 11 0,000 0,04696633 0,07687295 ! somatic diversification of immunoglobulins GO:0016445 11 11 0,000 0,04696633 0,07680474 ! RNA 3'-end processing GO:0031123 11 11 0,000 0,04696633 0,07673665 ! tube development GO:0035295 83 81 1,000 0,04814856 0,07859859 ! lymphocyte activation GO:0046649 82 81 1,000 0,04814856 0,07852903 ! ribonucleotide metabolic process GO:0009259 83 83 1,000 0,05030205 0,08196877 ! blood vessel morphogenesis GO:0048514 84 83 1,000 0,05030205 0,08189636 ! translational initiation GO:0006413 12 12 0,000 0,05112865 0,08316867 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 12 12 0,000 0,05112865 0,08309533 ! positive regulation of angiogenesis GO:0045766 12 12 0,000 0,05112865 0,08302212 ! initiation of viral infection GO:0019059 12 12 0,000 0,05112865 0,08294904 ! DNA catabolic process, endonucleolytic GO:0000737 12 12 0,000 0,05112865 0,08287608 ! iron ion transport GO:0006826 13 12 0,000 0,05112865 0,08280326 ! phosphatidylcholine metabolic process GO:0046470 12 12 0,000 0,05112865 0,08273056 ! amino sugar metabolic process GO:0006040 12 12 0,000 0,05112865 0,08265799 ! post-Golgi vesicle-mediated transport GO:0006892 12 12 0,000 0,05112865 0,08258555 ! protein amino acid ADP-ribosylation GO:0006471 12 12 0,000 0,05112865 0,08251323 ! heterophilic cell adhesion GO:0007157 12 12 0,000 0,05112865 0,08244104 ! collagen metabolic process GO:0032963 12 12 0,000 0,05112865 0,08236897 ! hindlimb morphogenesis GO:0035137 12 12 0,000 0,05112865 0,08229704 ! xenobiotic metabolic process GO:0006805 12 12 0,000 0,05112865 0,08222522 ! glutamate signaling pathway GO:0007215 12 12 0,000 0,05112865 0,08215354 ! C21-steroid hormone metabolic process GO:0008207 13 12 0,000 0,05112865 0,08208197 ! regulation of muscle cell differentiation GO:0051147 13 12 0,000 0,05112865 0,08201054 ! cellular response to hydrogen peroxide GO:0070301 12 12 0,000 0,05112865 0,08193922 GO:0042744|hydrogen peroxide catabolic process, ! actomyosin structure organization GO:0031032 12 12 0,000 0,05112865 0,08186803 ! microtubule organizing center organization GO:0031023 12 12 0,000 0,05112865 0,08179697 GO:0051297|centrosome organization, ! retinoid metabolic process GO:0001523 12 12 0,000 0,05112865 0,08172603 GO:0016101|diterpenoid metabolic process, ! mitotic chromosome condensation GO:0007076 12 12 0,000 0,05112865 0,08165521 ! positive regulation of innate immune response GO:0045089 12 12 0,000 0,05112865 0,08158451 ! GPI anchor biosynthetic process GO:0006506 12 12 0,000 0,05112865 0,08151393 GO:0006505|GPI anchor metabolic process, ! glycoprotein catabolic process GO:0006516 13 12 0,000 0,05112865 0,08144348 ! acute-phase response GO:0006953 12 12 0,000 0,05112865 0,08137315 ! deoxyribonucleotide catabolic process GO:0009264 12 12 0,000 0,05112865 0,08130294 ! vacuolar transport GO:0007034 12 12 0,000 0,05112865 0,08123285 ! polysaccharide catabolic process GO:0000272 12 12 0,000 0,05112865 0,08116288 ! vesicle docking during exocytosis GO:0006904 12 12 0,000 0,05112865 0,08109304 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 12 12 0,000 0,05112865 0,08102331 ! barbed-end actin filament capping GO:0051016 12 12 0,000 0,05112865 0,0809537 GO:0051693|actin filament capping, ! osteoblast differentiation GO:0001649 12 12 0,000 0,05112865 0,08088421 ! male gonad development GO:0008584 12 12 0,000 0,05112865 0,08081484 ! regulation of alpha-beta T cell activation GO:0046634 12 12 0,000 0,05112865 0,08074559 ! renal system process GO:0003014 12 12 0,000 0,05112865 0,08067646 ! regulation of tumor necrosis factor production GO:0032680 12 12 0,000 0,05112865 0,08060745 ! regulation of steroid metabolic process GO:0019218 12 12 0,000 0,05112865 0,08053855 ! fibroblast growth factor receptor signaling pathway GO:0008543 12 12 0,000 0,05112865 0,08046978 ! regulation of interleukin-6 production GO:0032675 12 12 0,000 0,05112865 0,08040112 ! pallium development GO:0021543 13 12 0,000 0,05112865 0,08033257 ! cell fate determination GO:0001709 12 12 0,000 0,05112865 0,08026415 ! regulation of chromosome organization GO:0033044 12 12 0,000 0,05112865 0,08019584 ! positive regulation of multicellular organism growth GO:0040018 12 12 0,000 0,05112865 0,08012764 ! G1 phase GO:0051318 13 12 0,000 0,05112865 0,08005956 ! regulation of response to biotic stimulus GO:0002831 12 12 0,000 0,05112865 0,0799916 ! positive regulation of adaptive immune response GO:0002821 12 12 0,000 0,05112865 0,07992375 ! detection of light stimulus GO:0009583 13 12 0,000 0,05112865 0,07985602 ! synaptogenesis GO:0007416 12 12 0,000 0,05112865 0,07978841 ! fat-soluble vitamin metabolic process GO:0006775 12 12 0,000 0,05112865 0,0797209 ! hormone transport GO:0009914 12 12 0,000 0,05112865 0,07965351 ! neurotransmitter secretion GO:0007269 14 12 0,000 0,05112865 0,07958624 ! heme biosynthetic process GO:0006783 12 12 0,000 0,05112865 0,07951908 ! spermatid differentiation GO:0048515 13 12 0,000 0,05112865 0,07945203 GO:0007286|spermatid development, ! aromatic compound catabolic process GO:0019439 13 12 0,000 0,05112865 0,07938509 ! pyrimidine nucleotide biosynthetic process GO:0006221 12 12 0,000 0,05112865 0,07931827 ! neural tube closure GO:0001843 13 12 0,000 0,05112865 0,07925156 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! regulation of mitotic metaphase/anaphase transition GO:0030071 13 12 0,000 0,05112865 0,07918496 ! negative regulation of translation GO:0017148 12 12 0,000 0,05112865 0,07911848 ! regulation of microtubule polymerization or depolymerization GO:0031110 12 12 0,000 0,05112865 0,0790521 ! positive regulation of smooth muscle cell proliferation GO:0048661 13 13 0,000 0,0552734 0,08538884 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 13 13 0,000 0,0552734 0,08531732 GO:0016444|somatic cell DNA recombination, ! negative regulation of actin filament polymerization GO:0030837 13 13 0,000 0,0552734 0,08524593 ! phenol metabolic process GO:0018958 13 13 0,000 0,0552734 0,08517465 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, GO:0009712|catechol metabolic process, ! G2/M transition of mitotic cell cycle GO:0000086 13 13 0,000 0,0552734 0,08510349 ! gluconeogenesis GO:0006094 13 13 0,000 0,0552734 0,08503245 ! 2'-deoxyribonucleotide metabolic process GO:0009394 13 13 0,000 0,0552734 0,08496154 GO:0019692|deoxyribose phosphate metabolic process, ! intra-Golgi vesicle-mediated transport GO:0006891 13 13 0,000 0,0552734 0,08489073 ! glycosaminoglycan biosynthetic process GO:0006024 13 13 0,000 0,0552734 0,08482005 ! positive regulation of JAK-STAT cascade GO:0046427 13 13 0,000 0,0552734 0,08474948 ! regeneration GO:0031099 13 13 0,000 0,0552734 0,08467904 ! keratinization GO:0031424 13 13 0,000 0,0552734 0,0846087 ! post-embryonic development GO:0009791 14 13 0,000 0,0552734 0,08453849 ! negative regulation of protein modification process GO:0031400 13 13 0,000 0,0552734 0,08446839 ! patterning of blood vessels GO:0001569 13 13 0,000 0,0552734 0,08439841 ! vasculogenesis GO:0001570 13 13 0,000 0,0552734 0,08432854 ! regulation of DNA recombination GO:0000018 13 13 0,000 0,0552734 0,08425879 ! regulation of innate immune response GO:0045088 13 13 0,000 0,0552734 0,08418916 ! multicellular organismal macromolecule metabolic process GO:0044259 13 13 0,000 0,0552734 0,08411964 ! response to corticosteroid stimulus GO:0031960 13 13 0,000 0,0552734 0,08405023 GO:0051384|response to glucocorticoid stimulus, ! multicellular organismal catabolic process GO:0044243 13 13 0,000 0,0552734 0,08398094 ! autophagy GO:0006914 13 13 0,000 0,0552734 0,08391176 ! ureteric bud development GO:0001657 13 13 0,000 0,0552734 0,0838427 ! regulation of endothelial cell migration GO:0010594 13 13 0,000 0,0552734 0,08377375 ! coenzyme catabolic process GO:0009109 13 13 0,000 0,0552734 0,08370491 GO:0046356|acetyl-CoA catabolic process, GO:0006099|tricarboxylic acid cycle, ! negative regulation of protein kinase cascade GO:0010741 13 13 0,000 0,0552734 0,08363619 ! purine nucleoside monophosphate metabolic process GO:0009126 13 13 0,000 0,0552734 0,08356758 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of viral reproduction GO:0050792 13 13 0,000 0,0552734 0,08349908 ! nucleobase metabolic process GO:0009112 13 13 0,000 0,0552734 0,0834307 ! positive regulation of neurogenesis GO:0050769 13 13 0,000 0,0552734 0,08336242 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 14 13 0,000 0,0552734 0,08329426 ! nucleotide-excision repair, DNA gap filling GO:0006297 13 13 0,000 0,0552734 0,08322621 ! vasodilation GO:0042311 14 13 0,000 0,0552734 0,08315827 ! positive regulation of leukocyte mediated immunity GO:0002705 13 13 0,000 0,0552734 0,08309044 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 13 13 0,000 0,0552734 0,08302272 ! glycosphingolipid metabolic process GO:0006687 13 13 0,000 0,0552734 0,08295511 GO:0006664|glycolipid metabolic process, ! positive regulation of locomotion GO:0040017 13 13 0,000 0,0552734 0,08288762 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, GO:0050920|regulation of chemotaxis, ! neural crest cell migration GO:0001755 14 13 0,000 0,0552734 0,08282023 ! neutrophil chemotaxis GO:0030593 14 13 0,000 0,0552734 0,08275295 ! long-chain fatty acid transport GO:0015909 13 13 0,000 0,0552734 0,08268578 ! immunoglobulin production GO:0002377 13 13 0,000 0,0552734 0,08261872 GO:0002440|production of molecular mediator of immune response, ! negative regulation of Wnt receptor signaling pathway GO:0030178 13 13 0,000 0,0552734 0,08255177 ! cell-cell junction organization GO:0045216 13 13 0,000 0,0552734 0,08248492 ! regulation of cell-substrate adhesion GO:0010810 14 13 0,000 0,0552734 0,08241819 GO:0001952|regulation of cell-matrix adhesion, ! negative regulation of myeloid cell differentiation GO:0045638 13 13 0,000 0,0552734 0,08235156 ! response to cytokine stimulus GO:0034097 13 13 0,000 0,0552734 0,08228504 ! activation of JUN kinase activity GO:0007257 13 13 0,000 0,0552734 0,08221863 ! terpenoid metabolic process GO:0006721 13 13 0,000 0,0552734 0,08215232 ! alkene biosynthetic process GO:0043450 13 13 0,000 0,0552734 0,08208612 GO:0019370|leukotriene biosynthetic process, ! porphyrin biosynthetic process GO:0006779 13 13 0,000 0,0552734 0,08202003 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of cytokine production GO:0001818 13 13 0,000 0,0552734 0,08195405 ! camera-type eye morphogenesis GO:0048593 13 13 0,000 0,0552734 0,08188817 ! pyrimidine nucleoside metabolic process GO:0006213 13 13 0,000 0,0552734 0,08182239 ! blastocyst development GO:0001824 13 13 0,000 0,0552734 0,08175673 ! telomere organization GO:0032200 13 13 0,000 0,0552734 0,08169116 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 13 13 0,000 0,0552734 0,08162571 ! regulation of amine transport GO:0051952 13 13 0,000 0,0552734 0,08156035 ! inner ear receptor cell differentiation GO:0060113 13 13 0,000 0,0552734 0,0814951 ! male gamete generation GO:0048232 90 88 1,000 0,05583603 0,08225884 GO:0007283|spermatogenesis, ! brain development GO:0007420 91 90 1,000 0,05810786 0,08553737 ! neuron fate commitment GO:0048663 14 14 0,000 0,05940065 0,08737063 ! sulfur amino acid metabolic process GO:0000096 14 14 0,000 0,05940065 0,08730095 ! regulation of interferon-gamma production GO:0032649 14 14 0,000 0,05940065 0,08723139 ! pyruvate metabolic process GO:0006090 14 14 0,000 0,05940065 0,08716194 ! cellular aldehyde metabolic process GO:0006081 14 14 0,000 0,05940065 0,0870926 ! acetyl-CoA metabolic process GO:0006084 14 14 0,000 0,05940065 0,08702337 ! cellular iron ion homeostasis GO:0006879 14 14 0,000 0,05940065 0,08695425 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 14 14 0,000 0,05940065 0,08688523 ! protein amino acid deacetylation GO:0006476 14 14 0,000 0,05940065 0,08681633 ! aminoglycan biosynthetic process GO:0006023 14 14 0,000 0,05940065 0,08674754 ! vesicle docking GO:0048278 14 14 0,000 0,05940065 0,08667886 ! superoxide metabolic process GO:0006801 15 14 0,000 0,05940065 0,08661028 ! macromolecular complex disassembly GO:0032984 15 14 0,000 0,05940065 0,08654181 ! calcium-dependent cell-cell adhesion GO:0016339 14 14 0,000 0,05940065 0,08647346 ! mechanoreceptor differentiation GO:0042490 14 14 0,000 0,05940065 0,08640521 ! isoprenoid biosynthetic process GO:0008299 14 14 0,000 0,05940065 0,08633706 ! hair cycle GO:0042633 14 14 0,000 0,05940065 0,08626903 GO:0022404|molting cycle process, GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042303|molting cycle, ! negative regulation of epithelial cell proliferation GO:0050680 14 14 0,000 0,05940065 0,0862011 ! immune response-activating cell surface receptor signaling pathway GO:0002429 14 14 0,000 0,05940065 0,08613328 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! response to retinoic acid GO:0032526 14 14 0,000 0,05940065 0,08606556 GO:0033189|response to vitamin A, ! multicellular organismal response to stress GO:0033555 14 14 0,000 0,05940065 0,08599795 ! lysosome organization GO:0007040 14 14 0,000 0,05940065 0,08593045 ! actin polymerization or depolymerization GO:0008154 15 14 0,000 0,05940065 0,08586305 ! D-ribose metabolic process GO:0006014 14 14 0,000 0,05940065 0,08579576 ! negative regulation of phosphorus metabolic process GO:0010563 14 14 0,000 0,05940065 0,08572858 GO:0045936|negative regulation of phosphate metabolic process, ! peptide transport GO:0015833 14 14 0,000 0,05940065 0,0856615 ! primary neural tube formation GO:0014020 15 14 0,000 0,05940065 0,08559452 ! peptide cross-linking GO:0018149 14 14 0,000 0,05940065 0,08552765 ! regulation of behavior GO:0050795 14 14 0,000 0,05940065 0,08546089 ! vitamin biosynthetic process GO:0009110 14 14 0,000 0,05940065 0,08539422 ! response to organic cyclic substance GO:0014070 15 14 0,000 0,05940065 0,08532767 ! leukotriene metabolic process GO:0006691 14 14 0,000 0,05940065 0,08526121 ! regulation of vasoconstriction GO:0019229 14 14 0,000 0,05940065 0,08519486 ! formation of primary germ layer GO:0001704 14 14 0,000 0,05940065 0,08512861 GO:0001707|mesoderm formation, ! DNA modification GO:0006304 14 14 0,000 0,05940065 0,08506247 ! collagen fibril organization GO:0030199 14 14 0,000 0,05940065 0,08499642 ! proteoglycan biosynthetic process GO:0030166 14 14 0,000 0,05940065 0,08493048 ! regulation of blood coagulation GO:0030193 15 14 0,000 0,05940065 0,08486465 ! positive regulation of inflammatory response GO:0050729 14 14 0,000 0,05940065 0,08479891 ! positive regulation of osteoblast differentiation GO:0045669 14 14 0,000 0,05940065 0,08473328 ! neuromuscular process controlling balance GO:0050885 14 14 0,000 0,05940065 0,08466775 ! aspartate family amino acid metabolic process GO:0009066 14 14 0,000 0,05940065 0,08460231 ! response to molecule of bacterial origin GO:0002237 14 14 0,000 0,05940065 0,08453698 ! negative regulation of protein polymerization GO:0032272 14 14 0,000 0,05940065 0,08447176 ! energy derivation by oxidation of organic compounds GO:0015980 94 92 1,000 0,0604119 0,08584359 ! blood vessel development GO:0001568 95 94 1,000 0,06274748 0,08909368 ! epidermis development GO:0008544 94 94 1,000 0,06274748 0,0890251 ! cofactor metabolic process GO:0051186 95 94 1,000 0,06274748 0,08895661 ! positive regulation of fibroblast proliferation GO:0048146 15 15 0,000 0,06351046 0,08996909 ! negative regulation of actin filament depolymerization GO:0030835 15 15 0,000 0,06351046 0,08989999 ! positive regulation of ossification GO:0045778 15 15 0,000 0,06351046 0,08983099 GO:0046852|positive regulation of bone remodeling, GO:0034105|positive regulation of tissue remodeling, ! negative regulation of protein complex assembly GO:0031333 15 15 0,000 0,06351046 0,0897621 ! protein amino acid O-linked glycosylation GO:0006493 15 15 0,000 0,06351046 0,08969332 ! cellular polysaccharide biosynthetic process GO:0033692 15 15 0,000 0,06351046 0,08962464 ! proteoglycan metabolic process GO:0006029 15 15 0,000 0,06351046 0,08955607 ! response to vitamin GO:0033273 15 15 0,000 0,06351046 0,0894876 ! striated muscle cell differentiation GO:0051146 16 15 0,000 0,06351046 0,08941924 ! odontogenesis of dentine-containing tooth GO:0042475 15 15 0,000 0,06351046 0,08935098 ! detection of stimulus involved in sensory perception GO:0050906 16 15 0,000 0,06351046 0,08928282 ! ovarian follicle development GO:0001541 15 15 0,000 0,06351046 0,08921477 ! antigen processing and presentation of peptide antigen GO:0048002 15 15 0,000 0,06351046 0,08914683 ! regulation of smooth muscle contraction GO:0006940 15 15 0,000 0,06351046 0,08907898 ! deoxyribonucleotide metabolic process GO:0009262 15 15 0,000 0,06351046 0,08901124 ! complement activation, classical pathway GO:0006958 15 15 0,000 0,06351046 0,0889436 ! heme metabolic process GO:0042168 15 15 0,000 0,06351046 0,08887607 ! mesoderm morphogenesis GO:0048332 15 15 0,000 0,06351046 0,08880864 ! chromosome condensation GO:0030261 15 15 0,000 0,06351046 0,08874131 ! response to mechanical stimulus GO:0009612 15 15 0,000 0,06351046 0,08867408 ! hydrogen peroxide metabolic process GO:0042743 15 15 0,000 0,06351046 0,08860695 ! regulation of biomineral formation GO:0070167 15 15 0,000 0,06351046 0,08853993 GO:0030500|regulation of bone mineralization, ! regulation of production of molecular mediator of immune response GO:0002700 15 15 0,000 0,06351046 0,088473 ! cyclic nucleotide biosynthetic process GO:0009190 15 15 0,000 0,06351046 0,08840618 ! cholesterol biosynthetic process GO:0006695 15 15 0,000 0,06351046 0,08833946 ! phospholipid transport GO:0015914 15 15 0,000 0,06351046 0,08827284 ! leukocyte homeostasis GO:0001776 15 15 0,000 0,06351046 0,08820632 ! regulation of cytokine secretion GO:0050707 15 15 0,000 0,06351046 0,0881399 ! glutathione metabolic process GO:0006749 16 15 0,000 0,06351046 0,08807358 ! nicotinamide metabolic process GO:0006769 15 15 0,000 0,06351046 0,08800735 GO:0046496|nicotinamide nucleotide metabolic process, ! positive regulation of B cell activation GO:0050871 15 15 0,000 0,06351046 0,08794123 ! positive regulation of myeloid cell differentiation GO:0045639 16 15 0,000 0,06351046 0,08787521 ! cellular alkene metabolic process GO:0043449 15 15 0,000 0,06351046 0,08780929 ! somatic diversification of immune receptors GO:0002200 15 15 0,000 0,06351046 0,08774346 ! protein homooligomerization GO:0051260 15 15 0,000 0,06351046 0,08767774 ! positive regulation of immune effector process GO:0002699 15 15 0,000 0,06351046 0,08761211 ! vasculature development GO:0001944 97 96 1,000 0,0651139 0,08975686 ! endocytosis GO:0006897 99 98 1,000 0,0675105 0,09299092 GO:0010324|membrane invagination, ! posttranscriptional regulation of gene expression GO:0010608 98 98 1,000 0,0675105 0,09292147 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 16 16 0,000 0,06760291 0,09297923 ! alkaloid metabolic process GO:0009820 16 16 0,000 0,06760291 0,0929099 ! regulation of synaptic plasticity GO:0048167 16 16 0,000 0,06760291 0,09284066 ! spliceosomal snRNP biogenesis GO:0000387 16 16 0,000 0,06760291 0,09277153 ! learning GO:0007612 16 16 0,000 0,06760291 0,09270251 ! circadian rhythm GO:0007623 16 16 0,000 0,06760291 0,09263358 ! inner ear morphogenesis GO:0042472 16 16 0,000 0,06760291 0,09256476 ! vacuole organization GO:0007033 16 16 0,000 0,06760291 0,09249604 ! cellular response to reactive oxygen species GO:0034614 16 16 0,000 0,06760291 0,09242743 ! positive regulation of cytoskeleton organization GO:0051495 16 16 0,000 0,06760291 0,09235891 ! vesicle targeting GO:0006903 17 16 0,000 0,06760291 0,0922905 ! fatty acid beta-oxidation GO:0006635 16 16 0,000 0,06760291 0,09222218 ! iron ion homeostasis GO:0055072 16 16 0,000 0,06760291 0,09215397 ! positive regulation of cell development GO:0010720 16 16 0,000 0,06760291 0,09208586 ! regulation of myeloid leukocyte differentiation GO:0002761 17 16 0,000 0,06760291 0,09201785 ! lymphocyte proliferation GO:0046651 16 16 0,000 0,06760291 0,09194994 ! regulation of systemic arterial blood pressure GO:0003073 17 16 0,000 0,06760291 0,09188213 ! cell fate specification GO:0001708 16 16 0,000 0,06760291 0,09181442 ! pentose metabolic process GO:0019321 16 16 0,000 0,06760291 0,09174681 ! fatty acid transport GO:0015908 16 16 0,000 0,06760291 0,0916793 ! positive regulation of MAPKKK cascade GO:0043410 17 16 0,000 0,06760291 0,09161189 ! regulation of microtubule cytoskeleton organization GO:0070507 16 16 0,000 0,06760291 0,09154458 ! cofactor catabolic process GO:0051187 16 16 0,000 0,06760291 0,09147737 ! ethanolamine and derivative metabolic process GO:0042439 17 16 0,000 0,06760291 0,09141025 ! polyol metabolic process GO:0019751 16 16 0,000 0,06760291 0,09134323 ! serine family amino acid metabolic process GO:0009069 16 16 0,000 0,06760291 0,09127632 ! glutamine family amino acid catabolic process GO:0009065 17 16 0,000 0,06760291 0,0912095 ! porphyrin metabolic process GO:0006778 16 16 0,000 0,06760291 0,09114277 GO:0033013|tetrapyrrole metabolic process, ! embryonic epithelial tube formation GO:0001838 17 16 0,000 0,06760291 0,09107615 GO:0001841|neural tube formation, ! regulation of JUN kinase activity GO:0043506 17 16 0,000 0,06760291 0,09100962 GO:0043507|positive regulation of JUN kinase activity, ! response to xenobiotic stimulus GO:0009410 16 16 0,000 0,06760291 0,09094319 ! regulation of coagulation GO:0050818 17 16 0,000 0,06760291 0,09087686 ! ectoderm development GO:0007398 99 99 1,000 0,06871991 0,09231107 ! negative regulation of transcription from RNA polymerase II promoter GO:0000122 103 100 1,000 0,06993662 0,09387704 ! hemopoiesis GO:0030097 104 100 1,000 0,06993662 0,09380872 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 17 17 0,000 0,07167808 0,09607469 ! regulation of smooth muscle cell proliferation GO:0048660 17 17 0,000 0,07167808 0,09600487 ! regulation of actin filament depolymerization GO:0030834 17 17 0,000 0,07167808 0,09593515 ! phosphoinositide biosynthetic process GO:0046489 17 17 0,000 0,07167808 0,09586553 ! nucleotide-excision repair, DNA damage removal GO:0000718 18 17 0,000 0,07167808 0,09579601 ! leukocyte adhesion GO:0007159 17 17 0,000 0,07167808 0,09572659 ! dicarboxylic acid metabolic process GO:0043648 18 17 0,000 0,07167808 0,09565727 ! sensory perception of smell GO:0007608 17 17 0,000 0,07167808 0,09558806 ! cell junction assembly GO:0034329 18 17 0,000 0,07167808 0,09551894 ! tissue remodeling GO:0048771 17 17 0,000 0,07167808 0,09544992 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 17 17 0,000 0,07167808 0,09538101 ! embryonic skeletal system morphogenesis GO:0048704 17 17 0,000 0,07167808 0,09531219 ! cellular carbohydrate biosynthetic process GO:0034637 17 17 0,000 0,07167808 0,09524347 ! development of primary male sexual characteristics GO:0046546 17 17 0,000 0,07167808 0,09517485 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 17 17 0,000 0,07167808 0,09510633 ! neural crest cell development GO:0014032 19 17 0,000 0,07167808 0,09503791 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 18 17 0,000 0,07167808 0,09496959 ! immune response-activating signal transduction GO:0002757 17 17 0,000 0,07167808 0,09490136 GO:0002764|immune response-regulating signal transduction, ! cell recognition GO:0008037 18 17 0,000 0,07167808 0,09483323 ! positive regulation of protein secretion GO:0050714 17 17 0,000 0,07167808 0,0947652 ! regulation of osteoblast differentiation GO:0045667 17 17 0,000 0,07167808 0,09469727 ! pyridine nucleotide metabolic process GO:0019362 17 17 0,000 0,07167808 0,09462944 ! pigmentation GO:0043473 17 17 0,000 0,07167808 0,0945617 ! myeloid leukocyte activation GO:0002274 18 17 0,000 0,07167808 0,09449406 ! adult locomotory behavior GO:0008344 17 17 0,000 0,07167808 0,09442652 ! embryonic organ development GO:0048568 17 17 0,000 0,07167808 0,09435907 ! regulation of calcium ion transport GO:0051924 17 17 0,000 0,07167808 0,09429172 ! liver development GO:0001889 17 17 0,000 0,07167808 0,09422446 ! gene silencing GO:0016458 17 17 0,000 0,07167808 0,0941573 ! mRNA export from nucleus GO:0006406 18 18 0,000 0,07573602 0,09941701 ! icosanoid biosynthetic process GO:0046456 18 18 0,000 0,07573602 0,09934625 ! meiosis I GO:0007127 18 18 0,000 0,07573602 0,09927559 ! regulation of metal ion transport GO:0010959 18 18 0,000 0,07573602 0,09920503 ! membrane docking GO:0022406 18 18 0,000 0,07573602 0,09913458 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 18 18 0,000 0,07573602 0,09906422 ! mononuclear cell proliferation GO:0032943 18 18 0,000 0,07573602 0,09899396 GO:0070661|leukocyte proliferation, ! response to calcium ion GO:0051592 18 18 0,000 0,07573602 0,0989238 ! negative regulation of response to external stimulus GO:0032102 18 18 0,000 0,07573602 0,09885374 ! cholesterol homeostasis GO:0042632 18 18 0,000 0,07573602 0,09878378 GO:0055092|sterol homeostasis, ! striated muscle contraction GO:0006941 18 18 0,000 0,07573602 0,09871392 ! ceramide metabolic process GO:0006672 18 18 0,000 0,07573602 0,09864416 GO:0046519|sphingoid metabolic process, ! ribonucleoside monophosphate metabolic process GO:0009161 18 18 0,000 0,07573602 0,09857449 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! telencephalon development GO:0021537 19 18 0,000 0,07573602 0,09850493 ! hexose biosynthetic process GO:0019319 18 18 0,000 0,07573602 0,09843546 ! negative regulation of MAP kinase activity GO:0043407 18 18 0,000 0,07573602 0,09836609 ! BMP signaling pathway GO:0030509 18 18 0,000 0,07573602 0,09829682 ! regulation of microtubule-based process GO:0032886 18 18 0,000 0,07573602 0,09822764 ! establishment of vesicle localization GO:0051650 19 18 0,000 0,07573602 0,09815857 ! activation of adenylate cyclase activity GO:0007190 19 19 0,000 0,07977681 0,10332302 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 19 19 0,000 0,07977681 0,10325047 GO:0006956|complement activation, ! glial cell differentiation GO:0010001 19 19 0,000 0,07977681 0,10317801 ! regulation of JAK-STAT cascade GO:0046425 19 19 0,000 0,07977681 0,10310565 ! feeding behavior GO:0007631 19 19 0,000 0,07977681 0,1030334 ! regulation of endothelial cell proliferation GO:0001936 19 19 0,000 0,07977681 0,10296125 ! peroxisome organization GO:0007031 19 19 0,000 0,07977681 0,1028892 ! positive regulation of T cell proliferation GO:0042102 19 19 0,000 0,07977681 0,10281725 ! regulation of striated muscle tissue development GO:0016202 20 19 0,000 0,07977681 0,1027454 ! multicellular organismal metabolic process GO:0044236 19 19 0,000 0,07977681 0,10267365 ! metanephros development GO:0001656 19 19 0,000 0,07977681 0,102602 ! cellular response to oxidative stress GO:0034599 19 19 0,000 0,07977681 0,10253045 ! regulation of lymphocyte mediated immunity GO:0002706 19 19 0,000 0,07977681 0,102459 ! positive regulation of T cell differentiation GO:0045582 19 19 0,000 0,07977681 0,10238765 ! nuclear-transcribed mRNA catabolic process GO:0000956 19 19 0,000 0,07977681 0,1023164 ! hormone biosynthetic process GO:0042446 19 19 0,000 0,07977681 0,10224525 ! biogenic amine biosynthetic process GO:0042401 20 19 0,000 0,07977681 0,10217419 ! dorsal/ventral pattern formation GO:0009953 19 19 0,000 0,07977681 0,10210324 ! eye morphogenesis GO:0048592 19 19 0,000 0,07977681 0,10203238 ! regulation of cell shape GO:0008360 21 19 0,000 0,07977681 0,10196163 ! placenta development GO:0001890 19 19 0,000 0,07977681 0,10189097 ! response to heat GO:0009408 19 19 0,000 0,07977681 0,1018204 ! vesicle localization GO:0051648 20 19 0,000 0,07977681 0,10174994 ! regulation of muscle development GO:0048634 21 20 0,000 0,08380052 0,106808 ! negative regulation of cell adhesion GO:0007162 21 20 0,000 0,08380052 0,10673419 ! establishment or maintenance of cell polarity GO:0007163 21 20 0,000 0,08380052 0,10666047 ! cytoskeleton-dependent intracellular transport GO:0030705 20 20 0,000 0,08380052 0,10658686 ! neural tube development GO:0021915 21 20 0,000 0,08380052 0,10651336 ! nucleus organization GO:0006997 20 20 0,000 0,08380052 0,10643995 ! phagocytosis GO:0006909 21 20 0,000 0,08380052 0,10636664 ! unsaturated fatty acid biosynthetic process GO:0006636 20 20 0,000 0,08380052 0,10629344 ! cyclic nucleotide metabolic process GO:0009187 20 20 0,000 0,08380052 0,10622033 ! chromatin remodeling GO:0006338 20 20 0,000 0,08380052 0,10614733 ! detection of abiotic stimulus GO:0009582 21 20 0,000 0,08380052 0,10607443 ! lipid oxidation GO:0034440 20 20 0,000 0,08380052 0,10600162 GO:0019395|fatty acid oxidation, ! female gamete generation GO:0007292 20 20 0,000 0,08380052 0,10592892 ! negative regulation of neuron apoptosis GO:0043524 21 20 0,000 0,08380052 0,10585632 ! monosaccharide biosynthetic process GO:0046364 20 20 0,000 0,08380052 0,10578381 ! RNA modification GO:0009451 20 20 0,000 0,08380052 0,10571141 ! single fertilization GO:0007338 21 20 0,000 0,08380052 0,1056391 ! regulation of B cell activation GO:0050864 20 20 0,000 0,08380052 0,10556689 ! mitotic sister chromatid segregation GO:0000070 21 21 0,000 0,08780723 0,11053874 ! mRNA catabolic process GO:0006402 21 21 0,000 0,08780723 0,11046329 ! positive regulation of adenylate cyclase activity GO:0045762 21 21 0,000 0,08780723 0,11038794 GO:0051349|positive regulation of lyase activity, GO:0031281|positive regulation of cyclase activity, ! protein amino acid lipidation GO:0006497 21 21 0,000 0,08780723 0,11031269 ! Notch signaling pathway GO:0007219 22 21 0,000 0,08780723 0,11023755 ! morphogenesis of embryonic epithelium GO:0016331 22 21 0,000 0,08780723 0,11016251 ! ear morphogenesis GO:0042471 21 21 0,000 0,08780723 0,11008757 ! organic anion transport GO:0015711 21 21 0,000 0,08780723 0,11001273 ! cholesterol transport GO:0030301 21 21 0,000 0,08780723 0,10993799 GO:0015918|sterol transport, ! spliceosome assembly GO:0000245 22 21 0,000 0,08780723 0,10986335 ! regulation of Rab protein signal transduction GO:0032483 21 21 0,000 0,08780723 0,10978882 GO:0032313|regulation of Rab GTPase activity, ! regulation of leukocyte mediated immunity GO:0002703 21 21 0,000 0,08780723 0,10971439 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 21 21 0,000 0,08780723 0,10964005 ! regulation of proteolysis GO:0030162 21 21 0,000 0,08780723 0,10956582 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 21 21 0,000 0,08780723 0,10949169 ! RNA export from nucleus GO:0006405 22 22 0,000 0,09179699 0,11438935 ! sister chromatid segregation GO:0000819 22 22 0,000 0,09179699 0,11431206 ! cellular amide metabolic process GO:0043603 22 22 0,000 0,09179699 0,11423488 ! regulation of ion transport GO:0043269 22 22 0,000 0,09179699 0,1141578 ! odontogenesis GO:0042476 22 22 0,000 0,09179699 0,11408082 ! cell junction organization GO:0034330 23 22 0,000 0,09179699 0,11400394 ! positive regulation of lymphocyte proliferation GO:0050671 22 22 0,000 0,09179699 0,11392717 GO:0032946|positive regulation of mononuclear cell proliferation, GO:0070665|positive regulation of leukocyte proliferation, GO:0070668|positive regulation of mast cell proliferation, ! embryonic skeletal system development GO:0048706 22 22 0,000 0,09179699 0,11385051 ! ovulation cycle process GO:0022602 22 22 0,000 0,09179699 0,11377394 ! spindle organization GO:0007051 22 22 0,000 0,09179699 0,11369748 ! pigment biosynthetic process GO:0046148 22 22 0,000 0,09179699 0,11362112 ! cell chemotaxis GO:0060326 23 22 0,000 0,09179699 0,11354487 GO:0030595|leukocyte chemotaxis, ! respiratory gaseous exchange GO:0007585 22 22 0,000 0,09179699 0,11346871 ! erythrocyte differentiation GO:0030218 23 22 0,000 0,09179699 0,11339266 ! male sex differentiation GO:0046661 22 22 0,000 0,09179699 0,11331671 ! sterol biosynthetic process GO:0016126 22 22 0,000 0,09179699 0,11324087 ! biopolymer methylation GO:0043414 22 22 0,000 0,09179699 0,11316512 GO:0032259|methylation, ! regulation of adaptive immune response GO:0002819 22 22 0,000 0,09179699 0,11308947 ! detection of external stimulus GO:0009581 23 22 0,000 0,09179699 0,11301393 ! neuron migration GO:0001764 22 22 0,000 0,09179699 0,11293849 ! regulation of Wnt receptor signaling pathway GO:0030111 23 22 0,000 0,09179699 0,11286314 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 22 22 0,000 0,09179699 0,1127879 ! positive regulation of lymphocyte differentiation GO:0045621 22 22 0,000 0,09179699 0,11271276 ! fatty acid catabolic process GO:0009062 23 22 0,000 0,09179699 0,11263772 ! aerobic respiration GO:0009060 22 22 0,000 0,09179699 0,11256278 ! cytokine production GO:0001816 22 22 0,000 0,09179699 0,11248793 ! cytokinesis GO:0000910 23 22 0,000 0,09179699 0,11241319 ! pyrimidine nucleotide metabolic process GO:0006220 22 22 0,000 0,09179699 0,11233855 ! response to hydrogen peroxide GO:0042542 24 23 0,000 0,09576988 0,11712269 ! epithelial cell differentiation GO:0030855 23 23 0,000 0,09576988 0,11704502 ! viral infectious cycle GO:0019058 23 23 0,000 0,09576988 0,11696746 ! response to estrogen stimulus GO:0043627 23 23 0,000 0,09576988 0,11689 ! negative regulation of protein complex disassembly GO:0043242 23 23 0,000 0,09576988 0,11681264 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 23 23 0,000 0,09576988 0,11673538 ! induction of apoptosis by extracellular signals GO:0008624 23 23 0,000 0,09576988 0,11665822 ! regulation of ARF protein signal transduction GO:0032012 23 23 0,000 0,09576988 0,11658117 ! endocrine system development GO:0035270 23 23 0,000 0,09576988 0,11650422 ! lipoprotein biosynthetic process GO:0042158 23 23 0,000 0,09576988 0,11642737 ! female gonad development GO:0008585 23 23 0,000 0,09576988 0,11635062 ! lipid homeostasis GO:0055088 23 23 0,000 0,09576988 0,11627397 ! Rho protein signal transduction GO:0007266 24 23 0,000 0,09576988 0,11619743 ! regulation of JNK cascade GO:0046328 25 23 0,000 0,09576988 0,11612098 ! gliogenesis GO:0042063 24 24 0,000 0,09972597 0,12083824 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 26 24 0,000 0,09972597 0,12075885 ! cellular amino acid biosynthetic process GO:0008652 24 24 0,000 0,09972597 0,12067956 ! heterocycle biosynthetic process GO:0018130 24 24 0,000 0,09972597 0,12060037 ! erythrocyte homeostasis GO:0034101 25 24 0,000 0,09972597 0,12052129 ! ovulation cycle GO:0042698 24 24 0,000 0,09972597 0,12044231 ! fertilization GO:0009566 25 24 0,000 0,09972597 0,12036344 ! oxidoreduction coenzyme metabolic process GO:0006733 24 24 0,000 0,09972597 0,12028466 ! androgen receptor signaling pathway GO:0030521 24 24 0,000 0,09972597 0,12020599 ! epithelial tube morphogenesis GO:0060562 25 24 0,000 0,09972597 0,12012743 ! regulation of actin filament polymerization GO:0030833 25 25 0,000 0,10366533 0,12479112 ! protein amino acid N-linked glycosylation GO:0006487 25 25 0,000 0,10366533 0,12470966 ! sensory perception of chemical stimulus GO:0007606 25 25 0,000 0,10366533 0,12462831 ! cellular component disassembly GO:0022411 26 25 0,000 0,10366533 0,12454706 ! alcohol biosynthetic process GO:0046165 25 25 0,000 0,10366533 0,12446593 ! development of primary female sexual characteristics GO:0046545 25 25 0,000 0,10366533 0,12438489 GO:0046660|female sex differentiation, ! polysaccharide biosynthetic process GO:0000271 25 25 0,000 0,10366533 0,12430397 ! excretion GO:0007588 25 25 0,000 0,10366533 0,12422315 ! generation of a signal involved in cell-cell signaling GO:0003001 27 25 0,000 0,10366533 0,12414243 ! gastrulation GO:0007369 25 25 0,000 0,10366533 0,12406182 ! icosanoid metabolic process GO:0006690 25 25 0,000 0,10366533 0,12398131 ! JAK-STAT cascade GO:0007259 26 25 0,000 0,10366533 0,12390091 ! positive regulation of cytokine production GO:0001819 25 25 0,000 0,10366533 0,12382061 ! positive regulation of defense response GO:0031349 26 26 0,000 0,10758802 0,12842274 ! glycolysis GO:0006096 26 26 0,000 0,10758802 0,12833962 ! transforming growth factor beta receptor signaling pathway GO:0007179 26 26 0,000 0,10758802 0,12825661 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 26 26 0,000 0,10758802 0,1281737 ! negative regulation of cell migration GO:0030336 26 26 0,000 0,10758802 0,1280909 ! cellular defense response GO:0006968 26 26 0,000 0,10758802 0,12800821 ! positive regulation of cytokine biosynthetic process GO:0042108 26 26 0,000 0,10758802 0,12792562 ! regulation of protein secretion GO:0050708 26 26 0,000 0,10758802 0,12784314 ! germ cell development GO:0007281 27 26 0,000 0,10758802 0,12776077 ! regulation of blood vessel size GO:0050880 27 26 0,000 0,10758802 0,1276785 GO:0035150|regulation of tube size, ! pigment metabolic process GO:0042440 26 26 0,000 0,10758802 0,12759634 ! chloride transport GO:0006821 27 27 0,000 0,11149411 0,13214382 ! regulation of neurotransmitter levels GO:0001505 31 27 0,000 0,11149411 0,1320589 ! learning or memory GO:0007611 28 27 0,000 0,11149411 0,13197408 ! monocarboxylic acid transport GO:0015718 27 27 0,000 0,11149411 0,13188937 ! peptide metabolic process GO:0006518 29 27 0,000 0,11149411 0,13180477 ! mesenchymal cell development GO:0014031 29 27 0,000 0,11149411 0,13172028 GO:0060485|mesenchyme development, GO:0048762|mesenchymal cell differentiation, ! inner ear development GO:0048839 27 27 0,000 0,11149411 0,1316359 ! defense response to bacterium GO:0042742 27 27 0,000 0,11149411 0,13155163 ! isoprenoid metabolic process GO:0006720 27 27 0,000 0,11149411 0,13146746 ! glutamine family amino acid metabolic process GO:0009064 28 27 0,000 0,11149411 0,1313834 ! cell growth GO:0016049 27 27 0,000 0,11149411 0,13129945 ! tRNA aminoacylation for protein translation GO:0006418 28 28 0,000 0,11538367 0,13579317 GO:0043038|amino acid activation, GO:0043039|tRNA aminoacylation, ! stress-activated protein kinase signaling pathway GO:0031098 28 28 0,000 0,11538367 0,13570652 GO:0007254|JNK cascade, ! neuromuscular process GO:0050905 28 28 0,000 0,11538367 0,13561997 ! regulation of muscle contraction GO:0006937 28 28 0,000 0,11538367 0,13553353 ! unsaturated fatty acid metabolic process GO:0033559 28 28 0,000 0,11538367 0,1354472 ! sulfur compound biosynthetic process GO:0044272 28 28 0,000 0,11538367 0,13536099 ! developmental growth GO:0048589 28 28 0,000 0,11538367 0,13527488 ! cartilage development GO:0051216 29 28 0,000 0,11538367 0,13518888 ! glycerophospholipid biosynthetic process GO:0046474 30 29 0,000 0,11925677 0,13963801 ! phosphoinositide metabolic process GO:0030384 29 29 0,000 0,11925677 0,13954936 ! leukocyte migration GO:0050900 30 29 0,000 0,11925677 0,13946081 ! branching morphogenesis of a tube GO:0048754 29 29 0,000 0,11925677 0,13937237 ! antigen processing and presentation GO:0019882 29 29 0,000 0,11925677 0,13928405 ! DNA-dependent DNA replication GO:0006261 29 29 0,000 0,11925677 0,13919584 ! tRNA processing GO:0008033 29 29 0,000 0,11925677 0,13910774 ! regulation of gene expression, epigenetic GO:0040029 29 29 0,000 0,11925677 0,13901976 ! adult behavior GO:0030534 30 29 0,000 0,11925677 0,13893188 ! regulation of protein polymerization GO:0032271 29 29 0,000 0,11925677 0,13884412 ! transition metal ion transport GO:0000041 31 30 0,000 0,12311348 0,14324378 ! RNA catabolic process GO:0006401 30 30 0,000 0,12311348 0,1431534 ! response to reactive oxygen species GO:0000302 31 30 0,000 0,12311348 0,14306314 ! ER to Golgi vesicle-mediated transport GO:0006888 30 30 0,000 0,12311348 0,142973 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 30 30 0,000 0,12311348 0,14288296 ! neuropeptide signaling pathway GO:0007218 30 30 0,000 0,12311348 0,14279304 ! regulation of protein complex disassembly GO:0043244 30 30 0,000 0,12311348 0,14270324 ! positive regulation of response to external stimulus GO:0032103 30 30 0,000 0,12311348 0,14261354 ! positive regulation of protein amino acid phosphorylation GO:0001934 30 30 0,000 0,12311348 0,14252396 ! skeletal system morphogenesis GO:0048705 31 30 0,000 0,12311348 0,14243449 ! response to temperature stimulus GO:0009266 30 30 0,000 0,12311348 0,14234513 ! regulation of ossification GO:0030278 30 30 0,000 0,12311348 0,14225589 ! vascular process in circulatory system GO:0003018 31 30 0,000 0,12311348 0,14216676 ! immunoglobulin mediated immune response GO:0016064 30 30 0,000 0,12311348 0,14207774 GO:0019724|B cell mediated immunity, ! regulation of inflammatory response GO:0050727 30 30 0,000 0,12311348 0,14198883 ! water-soluble vitamin metabolic process GO:0006767 30 30 0,000 0,12311348 0,14190003 ! vesicle organization GO:0016050 30 30 0,000 0,12311348 0,14181134 ! cellular amino acid derivative biosynthetic process GO:0042398 31 30 0,000 0,12311348 0,14172276 ! establishment of organelle localization GO:0051656 31 30 0,000 0,12311348 0,1416343 ! regulation of translational initiation GO:0006446 31 31 0,000 0,12695386 0,1459613 ! membrane fusion GO:0006944 31 31 0,000 0,12695386 0,1458703 ! negative regulation of cytoskeleton organization GO:0051494 32 31 0,000 0,12695386 0,14577942 ! lipoprotein metabolic process GO:0042157 31 31 0,000 0,12695386 0,14568864 ! ion transmembrane transport GO:0034220 31 31 0,000 0,12695386 0,14559799 GO:0015985|energy coupled proton transport, down electrochemical gradient, GO:0015986|ATP synthesis coupled proton transport, ! glycerolipid biosynthetic process GO:0045017 32 31 0,000 0,12695386 0,14550744 ! digestion GO:0007586 31 31 0,000 0,12695386 0,14541701 ! regulation of heart contraction GO:0008016 31 31 0,000 0,12695386 0,14532669 ! sphingolipid metabolic process GO:0006665 31 31 0,000 0,12695386 0,14523648 ! camera-type eye development GO:0043010 31 31 0,000 0,12695386 0,14514638 ! extracellular matrix organization GO:0030198 31 31 0,000 0,12695386 0,14505639 ! ribonucleoprotein complex assembly GO:0022618 32 31 0,000 0,12695386 0,14496652 ! regulation of myeloid cell differentiation GO:0045637 32 31 0,000 0,12695386 0,14487676 ! cell redox homeostasis GO:0045454 32 32 0,000 0,13077798 0,1491484 ! glucose catabolic process GO:0006007 32 32 0,000 0,13077798 0,14905616 ! lipid modification GO:0030258 32 32 0,000 0,13077798 0,14896404 ! glycosaminoglycan metabolic process GO:0030203 34 32 0,000 0,13077798 0,14887203 ! cell maturation GO:0048469 32 32 0,000 0,13077798 0,14878013 ! morphogenesis of a branching structure GO:0001763 32 32 0,000 0,13077798 0,14868835 ! nuclear export GO:0051168 32 32 0,000 0,13077798 0,14859668 ! kidney development GO:0001822 32 32 0,000 0,13077798 0,14850512 ! protein maturation by peptide bond cleavage GO:0051605 32 32 0,000 0,13077798 0,14841368 ! regulation of cellular response to stress GO:0080135 35 33 0,000 0,1345859 0,15264112 ! amino acid transport GO:0006865 33 33 0,000 0,1345859 0,15254724 ! activation of protein kinase activity GO:0032147 35 33 0,000 0,1345859 0,15245348 ! regulation of protein complex assembly GO:0043254 33 33 0,000 0,1345859 0,15235984 ! membrane lipid metabolic process GO:0006643 33 33 0,000 0,1345859 0,15226631 ! regulation of actin polymerization or depolymerization GO:0008064 33 33 0,000 0,1345859 0,15217289 ! regulation of synaptic transmission GO:0050804 33 33 0,000 0,1345859 0,15207959 ! regulation of actin filament length GO:0030832 34 34 0,000 0,1383777 0,15626844 ! regulation of bone remodeling GO:0046850 34 34 0,000 0,1383777 0,15617275 ! response to metal ion GO:0010038 34 34 0,000 0,1383777 0,15607717 ! ear development GO:0043583 34 34 0,000 0,1383777 0,15598171 ! muscle cell differentiation GO:0042692 35 34 0,000 0,1383777 0,15588637 ! coenzyme biosynthetic process GO:0009108 34 34 0,000 0,1383777 0,15579114 ! nucleoside monophosphate biosynthetic process GO:0009124 34 34 0,000 0,1383777 0,15569603 ! regulation of lipid metabolic process GO:0019216 34 34 0,000 0,1383777 0,15560103 ! secondary metabolic process GO:0019748 34 34 0,000 0,1383777 0,15550616 ! negative regulation of response to stimulus GO:0048585 34 34 0,000 0,1383777 0,15541139 ! detection of stimulus GO:0051606 36 34 0,000 0,1383777 0,15531674 ! acute inflammatory response GO:0002526 35 35 0,000 0,14215343 0,15945756 ! regulation of cellular component size GO:0032535 35 35 0,000 0,14215343 0,15936057 ! regulation of cytokine biosynthetic process GO:0042035 35 35 0,000 0,14215343 0,15926369 ! mesoderm development GO:0007498 35 35 0,000 0,14215343 0,15916693 ! regulation of tissue remodeling GO:0034103 35 35 0,000 0,14215343 0,15907029 ! inorganic anion transport GO:0015698 35 35 0,000 0,14215343 0,15897377 ! response to steroid hormone stimulus GO:0048545 35 35 0,000 0,14215343 0,15887736 ! regulation of immune effector process GO:0002697 35 35 0,000 0,14215343 0,15878107 ! hydrogen transport GO:0006818 36 36 0,000 0,14591317 0,16288187 GO:0015992|proton transport, ! response to inorganic substance GO:0010035 36 36 0,000 0,14591317 0,16278327 ! aminoglycan metabolic process GO:0006022 38 36 0,000 0,14591317 0,16268479 ! oxygen and reactive oxygen species metabolic process GO:0006800 37 36 0,000 0,14591317 0,16258644 ! embryonic limb morphogenesis GO:0030326 36 36 0,000 0,14591317 0,1624882 GO:0035113|embryonic appendage morphogenesis, ! female pregnancy GO:0007565 37 36 0,000 0,14591317 0,16239008 ! RNA elongation from RNA polymerase II promoter GO:0006368 36 36 0,000 0,14591317 0,16229207 ! integrin-mediated signaling pathway GO:0007229 36 36 0,000 0,14591317 0,16219419 ! regulation of transmission of nerve impulse GO:0051969 36 36 0,000 0,14591317 0,16209642 ! gonad development GO:0008406 36 36 0,000 0,14591317 0,16199877 ! activation of immune response GO:0002253 36 36 0,000 0,14591317 0,16190124 ! coagulation GO:0050817 39 36 0,000 0,14591317 0,16180383 GO:0007596|blood coagulation, ! lymphocyte mediated immunity GO:0002449 37 37 0,000 0,14965697 0,16585556 ! eye development GO:0001654 37 37 0,000 0,14965697 0,16575589 ! ATP synthesis coupled electron transport GO:0042773 37 37 0,000 0,14965697 0,16565634 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! cellular amino acid catabolic process GO:0009063 38 37 0,000 0,14965697 0,1655569 ! regulation of Rho protein signal transduction GO:0035023 37 37 0,000 0,14965697 0,16545759 ! adaptive immune response GO:0002250 37 37 0,000 0,14965697 0,16535839 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! neurotransmitter transport GO:0006836 40 38 0,000 0,15338491 0,16937591 ! cellular hormone metabolic process GO:0034754 39 38 0,000 0,15338491 0,16927449 ! exocytosis GO:0006887 40 38 0,000 0,15338491 0,16917318 ! cell-matrix adhesion GO:0007160 39 38 0,000 0,15338491 0,169072 ! urogenital system development GO:0001655 38 38 0,000 0,15338491 0,16897095 ! hexose catabolic process GO:0019320 38 38 0,000 0,15338491 0,16887001 ! RNA elongation GO:0006354 38 38 0,000 0,15338491 0,16876919 ! regulation of neurological system process GO:0031644 38 38 0,000 0,15338491 0,16866849 ! steroid hormone receptor signaling pathway GO:0030518 38 38 0,000 0,15338491 0,16856791 ! regulation of homeostatic process GO:0032844 38 38 0,000 0,15338491 0,16846746 ! hemostasis GO:0007599 42 39 0,000 0,15709705 0,17244185 ! positive regulation of protein modification process GO:0031401 39 39 0,000 0,15709705 0,1723392 ! response to unfolded protein GO:0006986 39 39 0,000 0,15709705 0,17223668 ! nucleoside monophosphate metabolic process GO:0009123 39 39 0,000 0,15709705 0,17213428 ! fatty acid biosynthetic process GO:0006633 39 39 0,000 0,15709705 0,172032 ! cytokine-mediated signaling pathway GO:0019221 39 39 0,000 0,15709705 0,17192985 ! intracellular protein transmembrane transport GO:0065002 39 39 0,000 0,15709705 0,17182781 ! regulation of MAPKKK cascade GO:0043408 41 39 0,000 0,15709705 0,1717259 ! positive regulation of T cell activation GO:0050870 39 39 0,000 0,15709705 0,1716241 ! developmental maturation GO:0021700 39 39 0,000 0,15709705 0,17152243 ! limb development GO:0060173 39 39 0,000 0,15709705 0,17142088 GO:0048736|appendage development, GO:0035107|appendage morphogenesis, ! DNA catabolic process GO:0006308 41 40 0,000 0,16079345 0,17535049 ! intracellular receptor-mediated signaling pathway GO:0030522 40 40 0,000 0,16079345 0,1752468 ! myeloid cell differentiation GO:0030099 42 40 0,000 0,16079345 0,17514322 ! organelle localization GO:0051640 41 40 0,000 0,16079345 0,17503977 ! amine catabolic process GO:0009310 42 41 0,000 0,16447418 0,17894092 ! elevation of cytosolic calcium ion concentration GO:0007204 41 41 0,000 0,16447418 0,17883535 ! phospholipid biosynthetic process GO:0008654 42 41 0,000 0,16447418 0,17872991 ! leukocyte mediated immunity GO:0002443 41 41 0,000 0,16447418 0,17862458 ! regulation of Ras GTPase activity GO:0032318 41 41 0,000 0,16447418 0,17851939 ! monosaccharide catabolic process GO:0046365 41 41 0,000 0,16447418 0,17841431 ! respiratory electron transport chain GO:0022904 43 42 0,000 0,16813931 0,18228279 ! cytosolic calcium ion homeostasis GO:0051480 42 42 0,000 0,16813931 0,18217563 ! cell-substrate adhesion GO:0031589 43 42 0,000 0,16813931 0,18206859 ! development of primary sexual characteristics GO:0045137 42 42 0,000 0,16813931 0,18196168 ! negative regulation of ligase activity GO:0051352 43 42 0,000 0,16813931 0,18185489 GO:0051444|negative regulation of ubiquitin-protein ligase activity, GO:0051436|negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle, ! response to protein stimulus GO:0051789 42 42 0,000 0,16813931 0,18174823 ! forebrain development GO:0030900 43 42 0,000 0,16813931 0,1816417 ! one-carbon metabolic process GO:0006730 42 42 0,000 0,16813931 0,18153529 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 42 42 0,000 0,16813931 0,181429 ! reproductive structure development GO:0048608 43 43 0,000 0,17178888 0,18525858 ! alcohol catabolic process GO:0046164 43 43 0,000 0,17178888 0,18515024 ! homeostasis of number of cells GO:0048872 44 43 0,000 0,17178888 0,18504203 ! humoral immune response GO:0006959 44 44 0,000 0,17542298 0,18884612 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 45 44 0,000 0,17542298 0,18873588 ! mRNA transport GO:0051028 44 44 0,000 0,17542298 0,18862576 ! negative regulation of organelle organization GO:0010639 45 44 0,000 0,17542298 0,18851578 ! vitamin metabolic process GO:0006766 44 44 0,000 0,17542298 0,18840592 ! positive regulation of lymphocyte activation GO:0051251 44 44 0,000 0,17542298 0,18829619 ! amine biosynthetic process GO:0009309 46 45 0,000 0,17904167 0,19206856 ! homophilic cell adhesion GO:0007156 45 45 0,000 0,17904167 0,19195683 ! regulation of actin cytoskeleton organization GO:0032956 46 45 0,000 0,17904167 0,19184523 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 46 45 0,000 0,17904167 0,19173375 ! steroid biosynthetic process GO:0006694 46 45 0,000 0,17904167 0,19162241 ! protein processing GO:0016485 45 45 0,000 0,17904167 0,1915112 ! regulation of actin filament-based process GO:0032970 47 46 0,000 0,18264499 0,19525216 ! tube morphogenesis GO:0035239 47 46 0,000 0,18264499 0,19513897 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 47 46 0,000 0,18264499 0,19502591 ! transcription initiation from RNA polymerase II promoter GO:0006367 46 46 0,000 0,18264499 0,19491298 ! positive regulation of ligase activity GO:0051351 47 46 0,000 0,18264499 0,19480019 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 47 47 0,000 0,18623303 0,19851213 ! regulation of blood pressure GO:0008217 48 47 0,000 0,18623303 0,19839739 ! sex differentiation GO:0007548 47 47 0,000 0,18623303 0,19828277 ! amine transport GO:0015837 47 47 0,000 0,18623303 0,19816829 ! rhythmic process GO:0048511 47 47 0,000 0,18623303 0,19805394 ! calcium ion transport GO:0006816 48 48 0,000 0,18980584 0,20173712 ! regulation of ubiquitin-protein ligase activity GO:0051438 49 48 0,000 0,18980584 0,20162084 ! glycerophospholipid metabolic process GO:0006650 49 48 0,000 0,18980584 0,2015047 ! DNA recombination GO:0006310 48 48 0,000 0,18980584 0,2013887 ! cellular lipid catabolic process GO:0044242 50 49 0,000 0,19336349 0,2050454 ! divalent metal ion transport GO:0070838 49 49 0,000 0,19336349 0,20492749 ! response to nutrient GO:0007584 49 49 0,000 0,19336349 0,20480971 ! response to bacterium GO:0009617 50 49 0,000 0,19336349 0,20469208 ! regulation of ligase activity GO:0051340 50 49 0,000 0,19336349 0,20457457 ! cofactor biosynthetic process GO:0051188 49 49 0,000 0,19336349 0,2044572 ! positive regulation of cell activation GO:0050867 49 49 0,000 0,19336349 0,20433997 GO:0002696|positive regulation of leukocyte activation, ! regulation of defense response GO:0031347 50 50 0,000 0,19690603 0,20796436 ! chromatin assembly GO:0031497 50 50 0,000 0,19690603 0,20784525 GO:0006334|nucleosome assembly, ! RNA transport GO:0050658 50 50 0,000 0,19690603 0,20772628 GO:0050657|nucleic acid transport, GO:0051236|establishment of RNA localization, ! nitrogen compound catabolic process GO:0044270 51 50 0,000 0,19690603 0,20760744 ! transcription initiation GO:0006352 50 50 0,000 0,19690603 0,20748874 ! biogenic amine metabolic process GO:0006576 52 51 0,000 0,20043353 0,21108514 ! positive regulation of immune response GO:0050778 51 51 0,000 0,20043353 0,21096458 ! rRNA metabolic process GO:0016072 51 51 0,000 0,20043353 0,21084417 GO:0006364|rRNA processing, ! protein-DNA complex assembly GO:0065004 51 51 0,000 0,20043353 0,21072389 ! ATP biosynthetic process GO:0006754 51 51 0,000 0,20043353 0,21060376 ! protein maturation GO:0051604 51 51 0,000 0,20043353 0,21048375 ! RNA localization GO:0006403 52 52 0,000 0,20394604 0,21405043 ! cholesterol metabolic process GO:0008203 52 52 0,000 0,20394604 0,21392861 ! regulation of GTPase activity GO:0043087 53 52 0,000 0,20394604 0,21380692 ! regulation of body fluid levels GO:0050878 55 52 0,000 0,20394604 0,21368537 ! sodium ion transport GO:0006814 53 53 0,000 0,20744365 0,2172265 ! tRNA metabolic process GO:0006399 53 53 0,000 0,20744365 0,21710315 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 53 53 0,000 0,20744365 0,21697993 ! carbohydrate biosynthetic process GO:0016051 53 53 0,000 0,20744365 0,21685686 ! carbohydrate catabolic process GO:0016052 53 53 0,000 0,20744365 0,21673392 ! response to virus GO:0009615 54 54 0,000 0,21092639 0,22024778 ! sulfur metabolic process GO:0006790 55 54 0,000 0,21092639 0,22012307 ! negative regulation of multicellular organismal process GO:0051241 55 54 0,000 0,21092639 0,21999849 ! nucleosome organization GO:0034728 55 55 0,000 0,21439434 0,22348912 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 55 55 0,000 0,21439434 0,22336278 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! microtubule cytoskeleton organization GO:0000226 55 55 0,000 0,21439434 0,22323659 ! ribonucleoside triphosphate biosynthetic process GO:0009201 56 56 0,000 0,21784755 0,22670414 ! nucleoside triphosphate biosynthetic process GO:0009142 57 57 0,000 0,22128608 0,23015251 ! innate immune response GO:0045087 58 58 0,000 0,22471001 0,23358181 ! carboxylic acid transport GO:0046942 59 59 0,000 0,22811937 0,23699211 GO:0015849|organic acid transport, ! sterol metabolic process GO:0016125 59 59 0,000 0,22811937 0,23685859 ! cellular aromatic compound metabolic process GO:0006725 60 59 0,000 0,22811937 0,23672523 ! immune effector process GO:0002252 59 59 0,000 0,22811937 0,23659201 ! potassium ion transport GO:0006813 60 60 0,000 0,23151424 0,23997793 ! negative regulation of cellular protein metabolic process GO:0032269 60 60 0,000 0,23151424 0,23984303 ! protein polymerization GO:0051258 65 60 0,000 0,23151424 0,23970829 ! cellular respiration GO:0045333 62 61 0,000 0,23489468 0,24307181 ! proteasomal protein catabolic process GO:0010498 62 61 0,000 0,23489468 0,24293541 GO:0043161|proteasomal ubiquitin-dependent protein catabolic process, ! carboxylic acid catabolic process GO:0046395 63 61 0,000 0,23489468 0,24279916 GO:0016054|organic acid catabolic process, ! positive regulation of cellular protein metabolic process GO:0032270 61 61 0,000 0,23489468 0,24266306 ! lipid transport GO:0006869 62 62 0,000 0,23826074 0,24600255 ! morphogenesis of an epithelium GO:0002009 63 62 0,000 0,23826074 0,24586481 GO:0060429|epithelium development, ! regulation of cellular component biogenesis GO:0044087 63 62 0,000 0,23826074 0,24572722 ! di-, tri-valent inorganic cation transport GO:0015674 63 62 0,000 0,23826074 0,24558979 ! glucose metabolic process GO:0006006 63 63 0,000 0,24161248 0,24890542 ! regulation of response to external stimulus GO:0032101 65 64 0,000 0,24494997 0,25220267 ! regulation of cytoskeleton organization GO:0051493 66 64 0,000 0,24494997 0,25206186 ! anion transport GO:0006820 65 65 0,000 0,24827325 0,25533906 ! protein amino acid glycosylation GO:0006486 66 66 0,000 0,25158239 0,25859807 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! DNA packaging GO:0006323 66 66 0,000 0,25158239 0,25845393 ! Golgi vesicle transport GO:0048193 67 67 0,000 0,25487745 0,26169311 ! muscle contraction GO:0006936 67 67 0,000 0,25487745 0,26154741 ! purine ribonucleotide biosynthetic process GO:0009152 68 68 0,000 0,25815848 0,26476688 ! chromatin assembly or disassembly GO:0006333 68 68 0,000 0,25815848 0,26461962 ! regulation of translation GO:0006417 69 69 0,000 0,26142555 0,2678195 ! carboxylic acid biosynthetic process GO:0046394 70 70 0,000 0,2646787 0,27100158 GO:0016053|organic acid biosynthetic process, ! translational elongation GO:0006414 71 71 0,000 0,267918 0,27416595 ! oxidative phosphorylation GO:0006119 71 71 0,000 0,267918 0,27401381 ! calcium ion homeostasis GO:0055074 71 71 0,000 0,267918 0,27386183 GO:0006874|cellular calcium ion homeostasis, ! ribosome biogenesis GO:0042254 71 71 0,000 0,267918 0,27371002 ! negative regulation of signal transduction GO:0009968 71 71 0,000 0,267918 0,27355838 ! secretion by cell GO:0032940 75 72 0,000 0,27114351 0,2766985 ! muscle system process GO:0003012 72 72 0,000 0,27114351 0,27654537 ! sensory organ development GO:0007423 72 72 0,000 0,27114351 0,27639241 ! regulation of cytokine production GO:0001817 72 72 0,000 0,27114351 0,27623963 ! electron transport chain GO:0022900 75 74 0,000 0,27755335 0,28261372 ! ribonucleotide biosynthetic process GO:0009260 75 75 0,000 0,28073781 0,28569839 ! response to oxidative stress GO:0006979 76 75 0,000 0,28073781 0,28554072 ! negative regulation of cell communication GO:0010648 76 76 0,000 0,28390869 0,28860657 ! positive regulation of multicellular organismal process GO:0051240 76 76 0,000 0,28390869 0,28844748 ! cellular metal ion homeostasis GO:0006875 77 77 0,000 0,28706606 0,29149463 ! microtubule-based movement GO:0007018 82 78 0,000 0,29020997 0,29452477 ! metal ion homeostasis GO:0055065 78 78 0,000 0,29020997 0,29436267 ! regulation of immune response GO:0050776 78 78 0,000 0,29020997 0,29420076 ! glycoprotein biosynthetic process GO:0009101 80 80 0,000 0,29645763 0,30036911 ! lipid catabolic process GO:0016042 82 81 0,000 0,2995615 0,30334716 ! ncRNA processing GO:0034470 83 83 0,000 0,30572956 0,30942316 ! cellular amino acid derivative metabolic process GO:0006575 87 84 0,000 0,30879387 0,31235297 ! nitrogen compound biosynthetic process GO:0044271 86 85 0,000 0,31184511 0,31526634 ! positive regulation of cell differentiation GO:0045597 87 85 0,000 0,31184511 0,31509349 ! positive regulation of response to stimulus GO:0048584 86 85 0,000 0,31184511 0,31492084 ! organophosphate metabolic process GO:0019637 87 86 0,000 0,31488332 0,31781487 GO:0006644|phospholipid metabolic process, ! hexose metabolic process GO:0019318 87 86 0,000 0,31488332 0,31764092 ! purine nucleotide biosynthetic process GO:0006164 88 88 0,000 0,32092089 0,32355426 ! chemotaxis GO:0006935 90 89 0,000 0,32392035 0,32639979 GO:0042330|taxis, ! cellular di-, tri-valent inorganic cation homeostasis GO:0030005 89 89 0,000 0,32392035 0,32622143 ! regulation of Ras protein signal transduction GO:0046578 90 90 0,000 0,32690701 0,32904949 ! di-, tri-valent inorganic cation homeostasis GO:0055066 91 91 0,000 0,32988091 0,33186164 ! DNA replication GO:0006260 91 91 0,000 0,32988091 0,33168059 ! visual perception GO:0007601 93 92 0,000 0,33284211 0,33447547 GO:0050953|sensory perception of light stimulus, ! fatty acid metabolic process GO:0006631 93 92 0,000 0,33284211 0,33429319 ! positive regulation of immune system process GO:0002684 92 92 0,000 0,33284211 0,33411112 ! tissue morphogenesis GO:0048729 94 93 0,000 0,33579066 0,33688741 ! regulation of response to stress GO:0080134 97 94 0,000 0,33872661 0,33964806 ! glycoprotein metabolic process GO:0009100 99 98 0,000 0,35034545 0,35110748 ! blood circulation GO:0008015 99 98 0,000 0,35034545 0,35091666 GO:0003013|circulatory system process, ! regulation of system process GO:0044057 98 98 0,000 0,35034545 0,35072605 ! anti-apoptosis GO:0006916 100 99 0,000 0,35321918 0,35341094 ! response to other organism GO:0051707 101 100 0,000 0,35608062 0,35608062