pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6681-VanDeVijver-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/vantveer-oligo_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! G1/S transition of mitotic cell cycle GO:0000082 21 21 4,000 8,55E-08 1,576E-04 ! negative regulation of homeostatic process GO:0032845 10 10 3,000 1,807E-07 1,665E-04 ! regulation of chromosome organization GO:0033044 12 12 3,000 4,225E-07 2,595E-04 ! negative regulation of DNA replication GO:0008156 13 13 3,000 6,078E-07 2,8E-04 ! regulation of DNA replication GO:0006275 32 31 4,000 6,85E-07 2,525E-04 ! negative regulation of cell growth GO:0030308 32 32 4,000 8,085E-07 2,483E-04 ! negative regulation of cell size GO:0045792 33 33 4,000 9,49E-07 2,498E-04 ! positive regulation of cell migration GO:0030335 36 36 4,000 1,489E-06 3,43E-04 ! T cell lineage commitment GO:0002360 5 5 2,000 1,671E-06 3,422E-04 ! negative regulation of growth GO:0045926 37 37 4,000 1,714E-06 3,16E-04 ! positive regulation of cell motion GO:0051272 39 39 4,000 2,246E-06 3,763E-04 ! cell cycle checkpoint GO:0000075 42 41 4,000 2,899E-06 4,452E-04 ! negative regulation of DNA metabolic process GO:0051053 19 19 3,000 3,215E-06 4,558E-04 ! regulation of lipid kinase activity GO:0043550 6 6 2,000 3,33E-06 4,383E-04 ! ER overload response GO:0006983 6 6 2,000 3,33E-06 4,091E-04 ! peptidyl-serine phosphorylation GO:0018105 6 6 2,000 3,33E-06 3,835E-04 ! phosphoinositide 3-kinase cascade GO:0014065 6 6 2,000 3,33E-06 3,61E-04 ! negative regulation of organelle organization GO:0010639 45 44 4,000 4,149E-06 4,249E-04 ! response to gamma radiation GO:0010332 8 7 2,000 5,804E-06 5,63E-04 ! positive regulation of MAP kinase activity GO:0043406 50 49 4,000 7,137E-06 6,577E-04 ! regulation of DNA metabolic process GO:0051052 51 50 4,000 7,897E-06 6,931E-04 ! positive regulation of transferase activity GO:0051347 91 88 5,000 8,574E-06 7,183E-04 GO:0033674|positive regulation of kinase activity, ! interphase of mitotic cell cycle GO:0051329 52 51 4,000 8,72E-06 6,987E-04 GO:0051325|interphase, ! peptidyl-serine modification GO:0018209 8 8 2,000 9,25E-06 7,103E-04 ! release of cytochrome c from mitochondria GO:0001836 9 8 2,000 9,25E-06 6,819E-04 ! negative regulation of cell cycle GO:0045786 92 91 5,000 1,042E-05 7,383E-04 ! negative regulation of cell cycle process GO:0010948 9 9 2,000 1,382E-05 9,433E-04 ! protein amino acid autophosphorylation GO:0046777 28 28 3,000 1,637E-05 1,078E-03 ! peptidyl-amino acid modification GO:0018193 61 59 4,000 1,798E-05 1,143E-03 ! response to UV GO:0009411 29 29 3,000 1,891E-05 1,162E-03 ! apoptotic mitochondrial changes GO:0008637 11 10 2,000 1,967E-05 1,169E-03 ! axonogenesis GO:0007409 66 62 4,000 2,295E-05 1,322E-03 ! negative regulation of cellular component organization GO:0051129 65 63 4,000 2,483E-05 1,387E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 11 11 2,000 2,693E-05 1,46E-03 ! regulation of MAP kinase activity GO:0043405 67 66 4,000 3,118E-05 1,642E-03 ! cell morphogenesis involved in neuron differentiation GO:0048667 72 67 4,000 3,356E-05 1,718E-03 GO:0048812|neuron projection morphogenesis, GO:0048858|cell projection morphogenesis, ! regulation of mitotic metaphase/anaphase transition GO:0030071 13 12 2,000 3,577E-05 1,782E-03 ! regulation of cell size GO:0008361 68 68 4,000 3,607E-05 1,749E-03 ! response to peptide hormone stimulus GO:0043434 36 34 3,000 3,619E-05 1,71E-03 ! regulation of mitotic cell cycle GO:0007346 72 69 4,000 3,873E-05 1,784E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 35 35 3,000 4,069E-05 1,829E-03 ! cell part morphogenesis GO:0032990 75 70 4,000 4,153E-05 1,823E-03 ! regulation of cell migration GO:0030334 71 71 4,000 4,45E-05 1,907E-03 ! mitochondrial membrane organization GO:0007006 13 13 2,000 4,632E-05 1,94E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 13 13 2,000 4,632E-05 1,897E-03 ! cell aging GO:0007569 13 13 2,000 4,632E-05 1,856E-03 ! response to endoplasmic reticulum stress GO:0034976 13 13 2,000 4,632E-05 1,816E-03 ! telomere organization GO:0032200 13 13 2,000 4,632E-05 1,778E-03 GO:0000723|telomere maintenance, ! protein tetramerization GO:0051262 13 13 2,000 4,632E-05 1,742E-03 ! response to drug GO:0042493 37 37 3,000 5,091E-05 1,876E-03 ! regulation of homeostatic process GO:0032844 38 38 3,000 5,667E-05 2,048E-03 ! positive regulation of epithelial cell proliferation GO:0050679 14 14 2,000 5,872E-05 2,081E-03 ! cell morphogenesis involved in differentiation GO:0000904 82 77 4,000 6,587E-05 2,291E-03 ! insulin receptor signaling pathway GO:0008286 17 15 2,000 7,311E-05 2,495E-03 ! ER-nuclear signaling pathway GO:0006984 15 15 2,000 7,311E-05 2,45E-03 ! response to ionizing radiation GO:0010212 16 15 2,000 7,311E-05 2,406E-03 ! regulation of locomotion GO:0040012 79 79 4,000 7,452E-05 2,41E-03 ! regulation of cell motion GO:0051270 79 79 4,000 7,452E-05 2,368E-03 ! neuron projection development GO:0031175 85 80 4,000 7,916E-05 2,473E-03 ! positive regulation of protein kinase activity GO:0045860 89 86 4,000 1,119E-04 3,436E-03 ! heart development GO:0007507 90 87 4,000 1,182E-04 3,571E-03 ! cellular response to hormone stimulus GO:0032870 48 46 3,000 1,213E-04 3,604E-03 ! B cell differentiation GO:0030183 18 18 2,000 1,296E-04 3,791E-03 ! symbiosis, encompassing mutualism through parasitism GO:0044403 18 18 2,000 1,296E-04 3,732E-03 ! DNA damage checkpoint GO:0000077 19 19 2,000 1,533E-04 4,346E-03 ! gland development GO:0048732 51 49 3,000 1,555E-04 4,343E-03 ! cell cycle arrest GO:0007050 49 49 3,000 1,555E-04 4,278E-03 ! anatomical structure homeostasis GO:0060249 51 50 3,000 1,684E-04 4,563E-03 ! epidermis development GO:0008544 94 94 4,000 1,706E-04 4,557E-03 ! regulation of cell growth GO:0001558 97 96 4,000 1,884E-04 4,96E-03 ! response to light stimulus GO:0009416 53 52 3,000 1,963E-04 5,096E-03 ! mitotic sister chromatid segregation GO:0000070 21 21 2,000 2,087E-04 5,343E-03 ! mammary gland development GO:0030879 23 21 2,000 2,087E-04 5,27E-03 ! DNA integrity checkpoint GO:0031570 21 21 2,000 2,087E-04 5,199E-03 ! regulation of multicellular organism growth GO:0040014 21 21 2,000 2,087E-04 5,13E-03 ! cellular response to insulin stimulus GO:0032869 23 21 2,000 2,087E-04 5,062E-03 ! ectoderm development GO:0007398 99 99 4,000 2,177E-04 5,212E-03 ! response to hormone stimulus GO:0009725 102 100 4,000 2,283E-04 5,393E-03 ! negative regulation of transcription from RNA polymerase II promoter GO:0000122 103 100 4,000 2,283E-04 5,325E-03 ! positive regulation of DNA metabolic process GO:0051054 23 22 2,000 2,408E-04 5,546E-03 ! sister chromatid segregation GO:0000819 22 22 2,000 2,408E-04 5,478E-03 ! mitotic cell cycle checkpoint GO:0007093 24 23 2,000 2,758E-04 6,198E-03 ! positive regulation of growth GO:0045927 23 23 2,000 2,758E-04 6,124E-03 ! regulation of protein localization GO:0032880 58 57 3,000 2,807E-04 6,158E-03 ! positive regulation of glucose metabolic process GO:0010907 5 5 1,000 3,098E-04 6,717E-03 ! metencephalon development GO:0022037 5 5 1,000 3,098E-04 6,639E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 5 5 1,000 3,098E-04 6,562E-03 ! regulation of phospholipase A2 activity GO:0032429 5 5 1,000 3,098E-04 6,488E-03 ! fear response GO:0042596 5 5 1,000 3,098E-04 6,415E-03 ! protein heterooligomerization GO:0051291 5 5 1,000 3,098E-04 6,344E-03 ! response to UV-B GO:0010224 5 5 1,000 3,098E-04 6,274E-03 ! enucleate erythrocyte differentiation GO:0043353 6 5 1,000 3,098E-04 6,206E-03 ! regulation of mitochondrial membrane potential GO:0051881 5 5 1,000 3,098E-04 6,139E-03 ! cellular pigmentation GO:0033059 5 5 1,000 3,098E-04 6,074E-03 ! DNA methylation GO:0006306 5 5 1,000 3,098E-04 6,01E-03 GO:0006305|DNA alkylation, ! peptidyl-lysine modification GO:0018205 5 5 1,000 3,098E-04 5,947E-03 ! negative regulation of neuroblast proliferation GO:0007406 5 5 1,000 3,098E-04 5,886E-03 ! oocyte differentiation GO:0009994 5 5 1,000 3,098E-04 5,826E-03 GO:0048599|oocyte development, ! regulation of protein homodimerization activity GO:0043496 6 5 1,000 3,098E-04 5,767E-03 ! spleen development GO:0048536 5 5 1,000 3,098E-04 5,709E-03 ! positive regulation of homeostatic process GO:0032846 5 5 1,000 3,098E-04 5,653E-03 ! response to nicotine GO:0035094 5 5 1,000 3,098E-04 5,597E-03 ! mitochondrial transport GO:0006839 24 24 2,000 3,14E-04 5,618E-03 ! glucose homeostasis GO:0042593 24 24 2,000 3,14E-04 5,564E-03 GO:0033500|carbohydrate homeostasis, ! T cell differentiation GO:0030217 24 24 2,000 3,14E-04 5,511E-03 ! regulation of gene-specific transcription GO:0032583 25 25 2,000 3,554E-04 6,179E-03 ! regulation of intracellular protein transport GO:0033157 25 25 2,000 3,554E-04 6,121E-03 ! response to insulin stimulus GO:0032868 28 26 2,000 4,001E-04 6,828E-03 ! regulation of nucleocytoplasmic transport GO:0046822 27 27 2,000 4,484E-04 7,582E-03 ! N-terminal protein amino acid modification GO:0031365 6 6 1,000 4,63E-04 7,757E-03 GO:0018409|peptide or protein amino-terminal blocking, ! virus-host interaction GO:0019048 6 6 1,000 4,63E-04 7,688E-03 ! pathogenesis GO:0009405 6 6 1,000 4,63E-04 7,619E-03 ! nerve growth factor receptor signaling pathway GO:0048011 6 6 1,000 4,63E-04 7,552E-03 ! oligodendrocyte differentiation GO:0048709 6 6 1,000 4,63E-04 7,485E-03 ! telomere maintenance via telomerase GO:0007004 6 6 1,000 4,63E-04 7,42E-03 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 6 6 1,000 4,63E-04 7,356E-03 ! focal adhesion formation GO:0048041 7 6 1,000 4,63E-04 7,293E-03 ! negative regulation of T cell proliferation GO:0042130 6 6 1,000 4,63E-04 7,232E-03 GO:0070667|negative regulation of mast cell proliferation, ! negative regulation of ossification GO:0030279 6 6 1,000 4,63E-04 7,171E-03 ! G1 DNA damage checkpoint GO:0031571 6 6 1,000 4,63E-04 7,111E-03 ! regulation of T cell differentiation in the thymus GO:0033081 6 6 1,000 4,63E-04 7,052E-03 ! protein sumoylation GO:0016925 6 6 1,000 4,63E-04 6,994E-03 ! serine family amino acid biosynthetic process GO:0009070 6 6 1,000 4,63E-04 6,938E-03 ! thymus development GO:0048538 6 6 1,000 4,63E-04 6,882E-03 ! regulation of cellular carbohydrate catabolic process GO:0043471 6 6 1,000 4,63E-04 6,827E-03 GO:0043470|regulation of carbohydrate catabolic process, GO:0006110|regulation of glycolysis, ! regulation of embryonic development GO:0045995 6 6 1,000 4,63E-04 6,772E-03 ! localization within membrane GO:0051668 6 6 1,000 4,63E-04 6,719E-03 ! histone modification GO:0016570 28 28 2,000 5,002E-04 7,203E-03 ! striated muscle tissue development GO:0014706 69 67 3,000 5,229E-04 7,471E-03 ! response to radiation GO:0009314 70 68 3,000 5,533E-04 7,845E-03 ! positive regulation of cell cycle GO:0045787 29 29 2,000 5,558E-04 7,819E-03 ! regulation of epithelial cell proliferation GO:0050678 29 29 2,000 5,558E-04 7,76E-03 ! covalent chromatin modification GO:0016569 29 29 2,000 5,558E-04 7,702E-03 ! response to reactive oxygen species GO:0000302 31 30 2,000 6,151E-04 8,46E-03 ! muscle tissue development GO:0060537 72 70 3,000 6,179E-04 8,436E-03 ! positive regulation of cellular catabolic process GO:0031331 7 7 1,000 6,459E-04 8,753E-03 ! hair follicle morphogenesis GO:0031069 7 7 1,000 6,459E-04 8,689E-03 ! oxaloacetate metabolic process GO:0006107 7 7 1,000 6,459E-04 8,626E-03 ! digestive system development GO:0055123 7 7 1,000 6,459E-04 8,564E-03 GO:0048546|digestive tract morphogenesis, GO:0048547|gut morphogenesis, ! regulation of skeletal muscle fiber development GO:0048742 7 7 1,000 6,459E-04 8,503E-03 ! negative regulation of lymphocyte proliferation GO:0050672 7 7 1,000 6,459E-04 8,442E-03 GO:0032945|negative regulation of mononuclear cell proliferation, GO:0070664|negative regulation of leukocyte proliferation, ! response to X-ray GO:0010165 7 7 1,000 6,459E-04 8,383E-03 ! regulation of intracellular pH GO:0051453 7 7 1,000 6,459E-04 8,324E-03 ! positive regulation of carbohydrate metabolic process GO:0045913 7 7 1,000 6,459E-04 8,266E-03 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! alpha-beta T cell differentiation GO:0046632 7 7 1,000 6,459E-04 8,209E-03 ! RNA-dependent DNA replication GO:0006278 7 7 1,000 6,459E-04 8,153E-03 ! regulation of macrophage differentiation GO:0045649 8 7 1,000 6,459E-04 8,098E-03 ! negative regulation of T cell activation GO:0050868 7 7 1,000 6,459E-04 8,043E-03 ! B cell activation GO:0042113 31 31 2,000 6,784E-04 8,391E-03 ! aging GO:0007568 32 31 2,000 6,784E-04 8,335E-03 ! regulation of intracellular transport GO:0032386 31 31 2,000 6,784E-04 8,28E-03 ! regulation of neuron apoptosis GO:0043523 34 33 2,000 8,17E-04 9,906E-03 ! regulation of skeletal muscle tissue development GO:0048641 8 8 1,000 8,581E-04 0,01033648 ! negative regulation of bone remodeling GO:0046851 8 8 1,000 8,581E-04 0,01026936 ! T cell selection GO:0045058 8 8 1,000 8,581E-04 0,0102031 ! sex determination GO:0007530 8 8 1,000 8,581E-04 0,0101377 ! negative regulation of mitotic cell cycle GO:0045930 9 8 1,000 8,581E-04 0,01007313 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 8 8 1,000 8,581E-04 0,01000937 ! alpha-beta T cell activation GO:0046631 8 8 1,000 8,581E-04 9,946E-03 ! positive regulation of myeloid leukocyte differentiation GO:0002763 9 8 1,000 8,581E-04 9,884E-03 ! T cell homeostasis GO:0043029 8 8 1,000 8,581E-04 9,823E-03 ! regulation of generation of precursor metabolites and energy GO:0043467 8 8 1,000 8,581E-04 9,762E-03 ! response to metal ion GO:0010038 34 34 2,000 8,925E-04 0,01009162 ! regulation of lipid metabolic process GO:0019216 34 34 2,000 8,925E-04 0,01003008 ! multicellular organism reproduction GO:0032504 36 35 2,000 9,724E-04 0,01086131 GO:0048609|reproductive process in a multicellular organism, ! response to inorganic substance GO:0010035 36 36 2,000 1,057E-03 0,01173131 ! regulation of mitosis GO:0007088 37 36 2,000 1,057E-03 0,01166106 GO:0051783|regulation of nuclear division, ! positive regulation of organelle organization GO:0010638 36 36 2,000 1,057E-03 0,01159165 ! regulation of nitric-oxide synthase activity GO:0050999 9 9 1,000 1,099E-03 0,01198849 ! response to alkaloid GO:0043279 10 9 1,000 1,099E-03 0,01191797 ! response to ethanol GO:0045471 9 9 1,000 1,099E-03 0,01184828 ! activation of pro-apoptotic gene products GO:0008633 9 9 1,000 1,099E-03 0,01177939 ! branching involved in ureteric bud morphogenesis GO:0001658 9 9 1,000 1,099E-03 0,0117113 GO:0060675|ureteric bud morphogenesis, ! prostaglandin metabolic process GO:0006693 9 9 1,000 1,099E-03 0,011644 GO:0006692|prostanoid metabolic process, ! T cell differentiation in the thymus GO:0033077 9 9 1,000 1,099E-03 0,01157746 ! regulation of cellular pH GO:0030641 9 9 1,000 1,099E-03 0,01151168 ! histone acetylation GO:0016573 9 9 1,000 1,099E-03 0,01144664 ! negative regulation of tissue remodeling GO:0034104 9 9 1,000 1,099E-03 0,01138233 ! defense response to virus GO:0051607 9 9 1,000 1,099E-03 0,01131874 ! DNA damage response, signal transduction GO:0042770 37 37 2,000 1,145E-03 0,01172748 ! chromosome segregation GO:0007059 38 38 2,000 1,239E-03 0,0126129 ! axon guidance GO:0007411 39 38 2,000 1,239E-03 0,01254359 ! activation of MAPK activity GO:0000187 39 39 2,000 1,337E-03 0,01346186 ! nucleotide-excision repair GO:0006289 40 39 2,000 1,337E-03 0,0133887 ! lymphocyte differentiation GO:0030098 39 39 2,000 1,337E-03 0,01331633 ! protein oligomerization GO:0051259 39 39 2,000 1,337E-03 0,01324473 ! regulation of glucose metabolic process GO:0010906 10 10 1,000 1,369E-03 0,0134947 ! epidermis morphogenesis GO:0048730 10 10 1,000 1,369E-03 0,01342292 ! plasma membrane organization GO:0007009 10 10 1,000 1,369E-03 0,0133519 ! cell-substrate junction assembly GO:0007044 11 10 1,000 1,369E-03 0,01328162 ! neuromuscular junction development GO:0007528 10 10 1,000 1,369E-03 0,01321209 ! regulation of protein binding GO:0043393 11 10 1,000 1,369E-03 0,01314327 ! histone deacetylation GO:0016575 10 10 1,000 1,369E-03 0,01307517 ! gland morphogenesis GO:0022612 10 10 1,000 1,369E-03 0,01300778 ! lymphocyte homeostasis GO:0002260 10 10 1,000 1,369E-03 0,01294107 ! gut development GO:0048565 10 10 1,000 1,369E-03 0,01287504 ! positive regulation of neuron apoptosis GO:0043525 10 10 1,000 1,369E-03 0,01280969 ! negative regulation of transferase activity GO:0051348 40 40 2,000 1,439E-03 0,01339832 ! brain development GO:0007420 91 90 3,000 1,588E-03 0,01470391 ! positive regulation of hormone secretion GO:0046887 11 11 1,000 1,668E-03 0,01536629 ! protein amino acid acetylation GO:0006473 11 11 1,000 1,668E-03 0,01528984 ! positive regulation of nucleocytoplasmic transport GO:0046824 11 11 1,000 1,668E-03 0,01521414 GO:0032388|positive regulation of intracellular transport, ! regulation of viral genome replication GO:0045069 11 11 1,000 1,668E-03 0,0151392 ! cellular response to starvation GO:0009267 11 11 1,000 1,668E-03 0,01506499 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 11 11 1,000 1,668E-03 0,0149915 ! G1/S transition checkpoint GO:0031575 12 11 1,000 1,668E-03 0,01491872 ! interaction with host GO:0051701 11 11 1,000 1,668E-03 0,01484665 ! regulation of monooxygenase activity GO:0032768 11 11 1,000 1,668E-03 0,01477527 ! oogenesis GO:0048477 11 11 1,000 1,668E-03 0,01470458 ! regulation of cellular carbohydrate metabolic process GO:0010675 11 11 1,000 1,668E-03 0,01463456 GO:0006109|regulation of carbohydrate metabolic process, ! hindbrain development GO:0030902 11 11 1,000 1,668E-03 0,0145652 ! negative regulation of lymphocyte activation GO:0051250 11 11 1,000 1,668E-03 0,0144965 ! mitochondrion organization GO:0007005 44 43 2,000 1,777E-03 0,01537566 ! homeostasis of number of cells GO:0048872 44 43 2,000 1,777E-03 0,01530381 ! male gonad development GO:0008584 12 12 1,000 1,994E-03 0,01709174 ! regulation of insulin secretion GO:0050796 12 12 1,000 1,994E-03 0,01701261 ! renal system process GO:0003014 12 12 1,000 1,994E-03 0,01693421 ! positive regulation of multicellular organism growth GO:0040018 12 12 1,000 1,994E-03 0,01685653 ! somitogenesis GO:0001756 13 12 1,000 1,994E-03 0,01677956 ! G1 phase GO:0051318 13 12 1,000 1,994E-03 0,01670329 ! cellular monovalent inorganic cation homeostasis GO:0030004 12 12 1,000 1,994E-03 0,01662771 ! regulation of membrane potential GO:0042391 46 46 2,000 2,16E-03 0,01793448 ! muscle organ development GO:0007517 102 100 3,000 2,34E-03 0,01933546 ! hemopoiesis GO:0030097 104 100 3,000 2,34E-03 0,01924914 ! positive regulation of DNA replication GO:0045740 14 13 1,000 2,348E-03 0,01923259 ! gluconeogenesis GO:0006094 13 13 1,000 2,348E-03 0,01914749 ! negative regulation of hormone secretion GO:0046888 13 13 1,000 2,348E-03 0,01906314 ! regeneration GO:0031099 13 13 1,000 2,348E-03 0,01897953 ! post-embryonic development GO:0009791 14 13 1,000 2,348E-03 0,01889665 ! response to corticosteroid stimulus GO:0031960 13 13 1,000 2,348E-03 0,01881449 GO:0051384|response to glucocorticoid stimulus, ! ureteric bud development GO:0001657 13 13 1,000 2,348E-03 0,01873305 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 13 13 1,000 2,348E-03 0,0186523 ! coenzyme catabolic process GO:0009109 13 13 1,000 2,348E-03 0,01857225 GO:0046356|acetyl-CoA catabolic process, GO:0006099|tricarboxylic acid cycle, ! regulation of peptide secretion GO:0002791 13 13 1,000 2,348E-03 0,01849288 ! regulation of viral reproduction GO:0050792 13 13 1,000 2,348E-03 0,01841419 ! negative regulation of phosphorylation GO:0042326 13 13 1,000 2,348E-03 0,01833616 ! negative regulation of leukocyte activation GO:0002695 13 13 1,000 2,348E-03 0,01825879 ! regulation of cell-substrate adhesion GO:0010810 14 13 1,000 2,348E-03 0,01818207 GO:0001952|regulation of cell-matrix adhesion, ! response to cytokine stimulus GO:0034097 13 13 1,000 2,348E-03 0,018106 ! tissue homeostasis GO:0001894 13 13 1,000 2,348E-03 0,01803056 GO:0048871|multicellular organismal homeostasis, ! regulation of cell cycle process GO:0010564 50 48 2,000 2,442E-03 0,0186769 ! leukocyte differentiation GO:0002521 50 49 2,000 2,591E-03 0,0197355 ! skeletal muscle tissue development GO:0007519 50 49 2,000 2,591E-03 0,01965428 GO:0060538|skeletal muscle organ development, ! pyruvate metabolic process GO:0006090 14 14 1,000 2,73E-03 0,02061688 ! acetyl-CoA metabolic process GO:0006084 14 14 1,000 2,73E-03 0,02053273 ! protein amino acid acylation GO:0043543 14 14 1,000 2,73E-03 0,02044926 ! protein amino acid deacetylation GO:0006476 14 14 1,000 2,73E-03 0,02036647 ! hair cycle GO:0042633 14 14 1,000 2,73E-03 0,02028435 GO:0022404|molting cycle process, GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042303|molting cycle, ! multicellular organismal response to stress GO:0033555 14 14 1,000 2,73E-03 0,02020289 ! negative regulation of phosphorus metabolic process GO:0010563 14 14 1,000 2,73E-03 0,02012207 GO:0045936|negative regulation of phosphate metabolic process, ! base-excision repair GO:0006284 14 14 1,000 2,73E-03 0,02004191 ! response to organic cyclic substance GO:0014070 15 14 1,000 2,73E-03 0,01996238 ! DNA modification GO:0006304 14 14 1,000 2,73E-03 0,01988347 ! T cell activation GO:0042110 51 50 2,000 2,746E-03 0,01992533 ! regulation of neurogenesis GO:0050767 51 50 2,000 2,746E-03 0,01984719 ! cell fate commitment GO:0045165 52 52 2,000 3,072E-03 0,0221179 ! protein import into nucleus, translocation GO:0000060 15 15 1,000 3,138E-03 0,02250472 ! striated muscle cell differentiation GO:0051146 16 15 1,000 3,138E-03 0,0224175 ! ovarian follicle development GO:0001541 15 15 1,000 3,138E-03 0,02233094 ! response to starvation GO:0042594 15 15 1,000 3,138E-03 0,02224505 ! leukocyte homeostasis GO:0001776 15 15 1,000 3,138E-03 0,02215982 ! positive regulation of myeloid cell differentiation GO:0045639 16 15 1,000 3,138E-03 0,02207524 ! negative regulation of cell activation GO:0050866 15 15 1,000 3,138E-03 0,02199131 ! response to hypoxia GO:0001666 53 53 2,000 3,244E-03 0,02264594 ! regulation of protein transport GO:0051223 53 53 2,000 3,244E-03 0,02256048 GO:0070201|regulation of establishment of protein localization, ! protein amino acid dephosphorylation GO:0006470 55 54 2,000 3,421E-03 0,02370506 ! response to oxygen levels GO:0070482 55 54 2,000 3,421E-03 0,02361628 ! positive regulation of mitosis GO:0045840 16 16 1,000 3,574E-03 0,02457597 GO:0051785|positive regulation of nuclear division, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 16 16 1,000 3,574E-03 0,02448461 ! cellular response to reactive oxygen species GO:0034614 16 16 1,000 3,574E-03 0,02439392 ! segmentation GO:0035282 17 16 1,000 3,574E-03 0,02430391 ! fatty acid beta-oxidation GO:0006635 16 16 1,000 3,574E-03 0,02421456 ! triglyceride metabolic process GO:0006641 16 16 1,000 3,574E-03 0,02412586 ! positive regulation of cell development GO:0010720 16 16 1,000 3,574E-03 0,02403781 ! regulation of myeloid leukocyte differentiation GO:0002761 17 16 1,000 3,574E-03 0,0239504 ! lymphocyte proliferation GO:0046651 16 16 1,000 3,574E-03 0,02386362 ! cellular response to nutrient levels GO:0031669 16 16 1,000 3,574E-03 0,02377747 ! cofactor catabolic process GO:0051187 16 16 1,000 3,574E-03 0,02369194 ! serine family amino acid metabolic process GO:0009069 16 16 1,000 3,574E-03 0,02360702 ! positive regulation of catabolic process GO:0009896 16 16 1,000 3,574E-03 0,02352271 ! in utero embryonic development GO:0001701 55 55 2,000 3,605E-03 0,02364182 ! regulation of cell adhesion GO:0030155 56 55 2,000 3,605E-03 0,02355798 ! reproductive developmental process GO:0003006 56 56 2,000 3,794E-03 0,0247069 ! regulation of nervous system development GO:0051960 57 56 2,000 3,794E-03 0,0246199 ! regulation of binding GO:0051098 60 57 2,000 3,989E-03 0,02579566 ! regulation of fibroblast proliferation GO:0048145 17 17 1,000 4,036E-03 0,02600664 ! positive regulation of cell adhesion GO:0045785 17 17 1,000 4,036E-03 0,02591603 ! myelination GO:0042552 17 17 1,000 4,036E-03 0,02582604 ! nucleotide-excision repair, DNA damage removal GO:0000718 18 17 1,000 4,036E-03 0,02573668 ! dicarboxylic acid metabolic process GO:0043648 18 17 1,000 4,036E-03 0,02564793 ! cell junction assembly GO:0034329 18 17 1,000 4,036E-03 0,02555979 ! development of primary male sexual characteristics GO:0046546 17 17 1,000 4,036E-03 0,02547226 ! response to toxin GO:0009636 18 17 1,000 4,036E-03 0,02538532 ! negative regulation of cell development GO:0010721 18 17 1,000 4,036E-03 0,02529898 GO:0050768|negative regulation of neurogenesis, ! regulation of oxidoreductase activity GO:0051341 17 17 1,000 4,036E-03 0,02521322 ! pigmentation GO:0043473 17 17 1,000 4,036E-03 0,02512804 ! dephosphorylation GO:0016311 60 59 2,000 4,398E-03 0,02728831 ! regulation of cell development GO:0060284 60 59 2,000 4,398E-03 0,02719673 ! regulation of cellular catabolic process GO:0031329 18 18 1,000 4,524E-03 0,02788556 ! meiosis I GO:0007127 18 18 1,000 4,524E-03 0,02779261 ! epidermal growth factor receptor signaling pathway GO:0007173 18 18 1,000 4,524E-03 0,02770028 ! mononuclear cell proliferation GO:0032943 18 18 1,000 4,524E-03 0,02760855 GO:0070661|leukocyte proliferation, ! response to calcium ion GO:0051592 18 18 1,000 4,524E-03 0,02751744 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 18 18 1,000 4,524E-03 0,02742692 ! neutral lipid metabolic process GO:0006638 18 18 1,000 4,524E-03 0,02733699 GO:0006639|acylglycerol metabolic process, ! hexose biosynthetic process GO:0019319 18 18 1,000 4,524E-03 0,02724766 ! cellular response to extracellular stimulus GO:0031668 18 18 1,000 4,524E-03 0,0271589 ! ensheathment of neurons GO:0007272 18 18 1,000 4,524E-03 0,02707073 GO:0008366|axon ensheathment, ! glial cell differentiation GO:0010001 19 19 1,000 5,038E-03 0,03005004 ! regulation of pH GO:0006885 19 19 1,000 5,038E-03 0,02995311 ! regulation of striated muscle tissue development GO:0016202 20 19 1,000 5,038E-03 0,0298568 ! multicellular organismal metabolic process GO:0044236 19 19 1,000 5,038E-03 0,0297611 ! peptidyl-tyrosine phosphorylation GO:0018108 20 19 1,000 5,038E-03 0,02966602 ! metanephros development GO:0001656 19 19 1,000 5,038E-03 0,02957154 ! cellular response to oxidative stress GO:0034599 19 19 1,000 5,038E-03 0,02947766 ! peripheral nervous system development GO:0007422 19 19 1,000 5,038E-03 0,02938438 ! regulation of protein stability GO:0031647 19 19 1,000 5,038E-03 0,02929168 ! response to heat GO:0009408 19 19 1,000 5,038E-03 0,02919957 ! glucose metabolic process GO:0006006 63 63 2,000 5,289E-03 0,03055466 ! regulation of muscle development GO:0048634 21 20 1,000 5,578E-03 0,03212625 ! organic ether metabolic process GO:0018904 20 20 1,000 5,578E-03 0,03202616 GO:0006662|glycerol ether metabolic process, ! positive regulation of gene-specific transcription GO:0043193 20 20 1,000 5,578E-03 0,0319267 ! peptidyl-tyrosine modification GO:0018212 21 20 1,000 5,578E-03 0,03182786 ! lipid oxidation GO:0034440 20 20 1,000 5,578E-03 0,03172962 GO:0019395|fatty acid oxidation, ! female gamete generation GO:0007292 20 20 1,000 5,578E-03 0,031632 ! negative regulation of neuron apoptosis GO:0043524 21 20 1,000 5,578E-03 0,03153496 ! monosaccharide biosynthetic process GO:0046364 20 20 1,000 5,578E-03 0,03143853 ! positive regulation of cellular component organization GO:0051130 65 65 2,000 5,772E-03 0,0324326 ! regulation of action potential in neuron GO:0019228 21 21 1,000 6,143E-03 0,03441352 ! negative regulation of hydrolase activity GO:0051346 21 21 1,000 6,143E-03 0,03430924 ! positive regulation of transcription factor activity GO:0051091 22 22 1,000 6,734E-03 0,03749209 GO:0090047|positive regulation of transcription regulator activity, ! cell junction organization GO:0034330 23 22 1,000 6,734E-03 0,03737917 ! hormone-mediated signaling GO:0009755 22 22 1,000 6,734E-03 0,03726692 ! ovulation cycle process GO:0022602 22 22 1,000 6,734E-03 0,03715534 ! spindle organization GO:0007051 22 22 1,000 6,734E-03 0,03704443 ! erythrocyte differentiation GO:0030218 23 22 1,000 6,734E-03 0,03693418 ! male sex differentiation GO:0046661 22 22 1,000 6,734E-03 0,03682458 ! biopolymer methylation GO:0043414 22 22 1,000 6,734E-03 0,03671563 GO:0032259|methylation, ! neuron migration GO:0001764 22 22 1,000 6,734E-03 0,03660732 ! fatty acid catabolic process GO:0009062 23 22 1,000 6,734E-03 0,03649966 ! aerobic respiration GO:0009060 22 22 1,000 6,734E-03 0,03639262 ! cytokinesis GO:0000910 23 22 1,000 6,734E-03 0,03628621 ! response to nutrient levels GO:0031667 69 69 2,000 6,817E-03 0,03662649 ! positive regulation of transport GO:0051050 71 70 2,000 7,094E-03 0,038007 ! wound healing GO:0042060 74 70 2,000 7,094E-03 0,03789684 ! growth GO:0040007 70 70 2,000 7,094E-03 0,03778731 ! response to hydrogen peroxide GO:0042542 24 23 1,000 7,349E-03 0,03902988 ! regulation of hormone secretion GO:0046883 23 23 1,000 7,349E-03 0,03891773 ! response to estrogen stimulus GO:0043627 23 23 1,000 7,349E-03 0,03880622 ! female gonad development GO:0008585 23 23 1,000 7,349E-03 0,03869534 ! monovalent inorganic cation homeostasis GO:0055067 23 23 1,000 7,349E-03 0,0385851 ! calcium-mediated signaling GO:0019722 23 23 1,000 7,349E-03 0,03847548 ! positive regulation of hydrolase activity GO:0051345 72 72 2,000 7,669E-03 0,04004054 ! response to extracellular stimulus GO:0009991 72 72 2,000 7,669E-03 0,03992743 ! gliogenesis GO:0042063 24 24 1,000 7,988E-03 0,04147038 ! erythrocyte homeostasis GO:0034101 25 24 1,000 7,988E-03 0,04135389 ! androgen receptor signaling pathway GO:0030521 24 24 1,000 7,988E-03 0,04123805 ! epithelial tube morphogenesis GO:0060562 25 24 1,000 7,988E-03 0,04112286 ! glucan metabolic process GO:0044042 25 24 1,000 7,988E-03 0,04100831 GO:0006073|cellular glucan metabolic process, GO:0005977|glycogen metabolic process, ! regulation of action potential GO:0001508 24 24 1,000 7,988E-03 0,0408944 ! cellular amino acid biosynthetic process GO:0008652 24 24 1,000 7,988E-03 0,04078112 ! ovulation cycle GO:0042698 24 24 1,000 7,988E-03 0,04066846 ! response to oxidative stress GO:0006979 76 75 2,000 8,582E-03 0,04357394 ! negative regulation of secretion GO:0051048 26 25 1,000 8,652E-03 0,04380551 ! alcohol biosynthetic process GO:0046165 25 25 1,000 8,652E-03 0,04368549 ! development of primary female sexual characteristics GO:0046545 25 25 1,000 8,652E-03 0,04356614 GO:0046660|female sex differentiation, ! regulation of T cell proliferation GO:0042129 25 25 1,000 8,652E-03 0,04344743 ! positive regulation of DNA binding GO:0043388 26 25 1,000 8,652E-03 0,04332936 ! heart morphogenesis GO:0003007 25 25 1,000 8,652E-03 0,04321194 ! icosanoid metabolic process GO:0006690 25 25 1,000 8,652E-03 0,04309515 ! negative regulation of immune system process GO:0002683 25 25 1,000 8,652E-03 0,04297899 ! glycolysis GO:0006096 26 26 1,000 9,339E-03 0,04627021 ! double-strand break repair GO:0006302 27 26 1,000 9,339E-03 0,04614616 ! germ cell development GO:0007281 27 26 1,000 9,339E-03 0,04602277 ! pigment metabolic process GO:0042440 26 26 1,000 9,339E-03 0,04590005 ! synapse organization GO:0050808 26 26 1,000 9,339E-03 0,04577797 ! positive regulation of binding GO:0051099 27 26 1,000 9,339E-03 0,04565654 ! negative regulation of cell migration GO:0030336 26 26 1,000 9,339E-03 0,04553576 ! induction of apoptosis by intracellular signals GO:0008629 26 26 1,000 9,339E-03 0,04541561 ! regulation of T cell differentiation GO:0045580 26 26 1,000 9,339E-03 0,0452961 ! energy reserve metabolic process GO:0006112 28 27 1,000 0,01005068 0,04861786 ! activation of caspase activity GO:0006919 27 27 1,000 0,01005068 0,04849059 ! mesenchymal cell development GO:0014031 29 27 1,000 0,01005068 0,04836398 GO:0060485|mesenchyme development, GO:0048762|mesenchymal cell differentiation, ! MAPKKK cascade GO:0000165 82 81 2,000 0,01059415 0,05084638 ! tube development GO:0035295 83 81 2,000 0,01059415 0,05071431 ! lymphocyte activation GO:0046649 82 81 2,000 0,01059415 0,05058293 ! unsaturated fatty acid metabolic process GO:0033559 28 28 1,000 0,01078533 0,0513627 ! developmental growth GO:0048589 28 28 1,000 0,01078533 0,05123032 ! regulation of mast cell proliferation GO:0070666 28 28 1,000 0,01078533 0,05109862 ! viral reproductive process GO:0022415 29 29 1,000 0,01154307 0,05454843 ! branching morphogenesis of a tube GO:0048754 29 29 1,000 0,01154307 0,05440892 ! positive regulation of protein transport GO:0051222 29 29 1,000 0,01154307 0,05427012 ! regulation of lymphocyte proliferation GO:0050670 29 29 1,000 0,01154307 0,05413203 GO:0032944|regulation of mononuclear cell proliferation, GO:0070663|regulation of leukocyte proliferation, ! regulation of gene expression, epigenetic GO:0040029 29 29 1,000 0,01154307 0,05399464 ! regulation of cellular localization GO:0060341 86 85 2,000 0,01207519 0,05634069 ! positive regulation of cell differentiation GO:0045597 87 85 2,000 0,01207519 0,05619841 ! positive regulation of peptidase activity GO:0010952 30 30 1,000 0,01232364 0,05721026 GO:0043280|positive regulation of caspase activity, ! activation of phospholipase C activity GO:0007202 30 30 1,000 0,01232364 0,05706652 GO:0010863|positive regulation of phospholipase C activity, ! response to temperature stimulus GO:0009266 30 30 1,000 0,01232364 0,05692349 ! regulation of ossification GO:0030278 30 30 1,000 0,01232364 0,05678118 ! vesicle organization GO:0016050 30 30 1,000 0,01232364 0,05663958 ! establishment of organelle localization GO:0051656 31 30 1,000 0,01232364 0,05649869 ! hexose metabolic process GO:0019318 87 86 2,000 0,01246317 0,05699657 ! regulation of anatomical structure morphogenesis GO:0022603 90 86 2,000 0,01246317 0,05685549 ! skeletal muscle fiber development GO:0048741 31 31 1,000 0,01312677 0,05973488 ! positive regulation of phospholipase activity GO:0010518 31 31 1,000 0,01312677 0,05958775 ! regulation of myeloid cell differentiation GO:0045637 32 31 1,000 0,01312677 0,05944135 ! negative regulation of cell motion GO:0051271 31 31 1,000 0,01312677 0,05929566 ! muscle fiber development GO:0048747 32 32 1,000 0,01395218 0,06287007 ! glucose catabolic process GO:0006007 32 32 1,000 0,01395218 0,06271673 ! lipid modification GO:0030258 32 32 1,000 0,01395218 0,06256413 ! regulation of phospholipase activity GO:0010517 32 32 1,000 0,01395218 0,06241228 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 32 32 1,000 0,01395218 0,06226116 ! morphogenesis of a branching structure GO:0001763 32 32 1,000 0,01395218 0,06211077 ! regulation of lymphocyte differentiation GO:0045619 32 32 1,000 0,01395218 0,06196111 ! kidney development GO:0001822 32 32 1,000 0,01395218 0,06181216 ! positive regulation of lipase activity GO:0060193 32 32 1,000 0,01395218 0,06166393 ! regulation of actin polymerization or depolymerization GO:0008064 33 33 1,000 0,01479961 0,06525282 ! regulation of neuron differentiation GO:0045664 34 33 1,000 0,01479961 0,06509708 ! energy derivation by oxidation of organic compounds GO:0015980 94 92 2,000 0,01494153 0,06556484 ! regulation of actin filament length GO:0030832 34 34 1,000 0,0156688 0,06859287 ! regulation of angiogenesis GO:0045765 35 34 1,000 0,0156688 0,06843033 ! regulation of bone remodeling GO:0046850 34 34 1,000 0,0156688 0,06826855 ! ear development GO:0043583 34 34 1,000 0,0156688 0,06810754 ! muscle cell differentiation GO:0042692 35 34 1,000 0,0156688 0,06794729 ! cellular polysaccharide metabolic process GO:0044264 35 34 1,000 0,0156688 0,06778779 ! secondary metabolic process GO:0019748 34 34 1,000 0,0156688 0,06762904 ! viral reproduction GO:0016032 34 34 1,000 0,0156688 0,06747102 ! regulation of cellular component size GO:0032535 35 35 1,000 0,01655949 0,07114019 ! positive regulation of phosphorylation GO:0042327 35 35 1,000 0,01655949 0,07097475 ! regulation of tissue remodeling GO:0034103 35 35 1,000 0,01655949 0,07081008 ! response to steroid hormone stimulus GO:0048545 35 35 1,000 0,01655949 0,07064616 ! oxygen and reactive oxygen species metabolic process GO:0006800 37 36 1,000 0,01747142 0,07436451 ! positive regulation of phosphorus metabolic process GO:0010562 36 36 1,000 0,01747142 0,07419317 GO:0045937|positive regulation of phosphate metabolic process, ! female pregnancy GO:0007565 37 36 1,000 0,01747142 0,07402261 ! RNA elongation from RNA polymerase II promoter GO:0006368 36 36 1,000 0,01747142 0,07385283 ! gonad development GO:0008406 36 36 1,000 0,01747142 0,07368383 ! regulation of lipase activity GO:0060191 36 36 1,000 0,01747142 0,0735156 ! coagulation GO:0050817 39 36 1,000 0,01747142 0,07334814 GO:0007596|blood coagulation, ! anti-apoptosis GO:0006916 100 99 2,000 0,01816255 0,07607633 ! regulation of transcription factor activity GO:0051090 38 37 1,000 0,01840434 0,07691428 GO:0090046|regulation of transcription regulator activity, ! meiosis GO:0007126 37 37 1,000 0,01840434 0,07674027 GO:0051327|M phase of meiotic cell cycle, ! negative regulation of protein kinase activity GO:0006469 37 37 1,000 0,01840434 0,07656704 ! lung development GO:0030324 38 37 1,000 0,01840434 0,07639459 ! regulation of Rho protein signal transduction GO:0035023 37 37 1,000 0,01840434 0,07622292 ! positive regulation of secretion GO:0051047 39 38 1,000 0,01935799 0,07999276 ! negative regulation of kinase activity GO:0033673 38 38 1,000 0,01935799 0,0798138 ! cell-matrix adhesion GO:0007160 39 38 1,000 0,01935799 0,07963565 ! urogenital system development GO:0001655 38 38 1,000 0,01935799 0,07945828 ! hexose catabolic process GO:0019320 38 38 1,000 0,01935799 0,07928171 ! RNA elongation GO:0006354 38 38 1,000 0,01935799 0,07910592 ! meiotic cell cycle GO:0051321 38 38 1,000 0,01935799 0,07893091 ! steroid hormone receptor signaling pathway GO:0030518 38 38 1,000 0,01935799 0,07875667 ! hemostasis GO:0007599 42 39 1,000 0,02033211 0,08253762 ! respiratory tube development GO:0030323 40 39 1,000 0,02033211 0,08235622 ! respiratory system development GO:0060541 40 39 1,000 0,02033211 0,08217561 ! DNA catabolic process GO:0006308 41 40 1,000 0,02132646 0,08600584 ! intracellular receptor-mediated signaling pathway GO:0030522 40 40 1,000 0,02132646 0,08581806 ! myeloid cell differentiation GO:0030099 42 40 1,000 0,02132646 0,08563109 ! organelle localization GO:0051640 41 40 1,000 0,02132646 0,08544494 ! regulation of caspase activity GO:0043281 41 41 1,000 0,02234079 0,08931471 ! monosaccharide catabolic process GO:0046365 41 41 1,000 0,02234079 0,08912139 ! regulation of endopeptidase activity GO:0052548 42 42 1,000 0,02337486 0,09304506 ! cell-substrate adhesion GO:0031589 43 42 1,000 0,02337486 0,09284453 ! development of primary sexual characteristics GO:0045137 42 42 1,000 0,02337486 0,09264487 ! negative regulation of ligase activity GO:0051352 43 42 1,000 0,02337486 0,09244606 GO:0051444|negative regulation of ubiquitin-protein ligase activity, GO:0051436|negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle, ! response to protein stimulus GO:0051789 42 42 1,000 0,02337486 0,0922481 ! forebrain development GO:0030900 43 42 1,000 0,02337486 0,09205099 ! one-carbon metabolic process GO:0006730 42 42 1,000 0,02337486 0,09185472 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 42 42 1,000 0,02337486 0,09165928 ! reproductive structure development GO:0048608 43 43 1,000 0,02442841 0,09558718 ! alcohol catabolic process GO:0046164 43 43 1,000 0,02442841 0,09538467 ! humoral immune response GO:0006959 44 44 1,000 0,02550121 0,09936308 ! protein import into nucleus GO:0006606 44 44 1,000 0,02550121 0,09915345 ! amine biosynthetic process GO:0009309 46 45 1,000 0,02659302 0,10318093 ! regulation of actin cytoskeleton organization GO:0032956 46 45 1,000 0,02659302 0,10296416 ! regulation of DNA binding GO:0051101 47 45 1,000 0,02659302 0,1027483 ! phosphoinositide-mediated signaling GO:0048015 45 45 1,000 0,02659302 0,10253335 ! nuclear import GO:0051170 45 45 1,000 0,02659302 0,10231929 ! Wnt receptor signaling pathway GO:0016055 46 45 1,000 0,02659302 0,10210612 ! regulation of actin filament-based process GO:0032970 47 46 1,000 0,0277036 0,10614914 ! tube morphogenesis GO:0035239 47 46 1,000 0,0277036 0,10592891 ! regulation of peptidase activity GO:0052547 46 46 1,000 0,0277036 0,10570959 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 47 46 1,000 0,0277036 0,10549119 ! transcription initiation from RNA polymerase II promoter GO:0006367 46 46 1,000 0,0277036 0,10527368 ! rRNA transcription GO:0009303 5 5 0,000 0,02803157 0,10630078 ! positive regulation of protein ubiquitination GO:0031398 5 5 0,000 0,02803157 0,1060825 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 5 5 0,000 0,02803157 0,10586512 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 5 5 0,000 0,02803157 0,10564862 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! neuron fate specification GO:0048665 5 5 0,000 0,02803157 0,10543301 ! hemoglobin biosynthetic process GO:0042541 5 5 0,000 0,02803157 0,10521828 ! reproductive cellular process GO:0048610 5 5 0,000 0,02803157 0,10500442 ! negative regulation of blood pressure GO:0045776 6 5 0,000 0,02803157 0,10479143 ! prostate gland development GO:0030850 5 5 0,000 0,02803157 0,10457931 ! water transport GO:0006833 5 5 0,000 0,02803157 0,10436803 GO:0042044|fluid transport, ! forebrain regionalization GO:0021871 5 5 0,000 0,02803157 0,10415761 ! DNA synthesis during DNA repair GO:0000731 5 5 0,000 0,02803157 0,10394804 ! positive regulation of B cell proliferation GO:0030890 5 5 0,000 0,02803157 0,10373931 ! glycerol metabolic process GO:0006071 5 5 0,000 0,02803157 0,10353142 ! regulation of cellular amine metabolic process GO:0033238 5 5 0,000 0,02803157 0,10332435 GO:0042053|regulation of dopamine metabolic process, GO:0042069|regulation of catecholamine metabolic process, ! meiotic prophase I GO:0007128 5 5 0,000 0,02803157 0,10311812 GO:0051324|prophase, ! cell volume homeostasis GO:0006884 5 5 0,000 0,02803157 0,1029127 ! regulation of epidermal growth factor receptor activity GO:0007176 5 5 0,000 0,02803157 0,1027081 GO:0010469|regulation of receptor activity, ! regulation of long-term neuronal synaptic plasticity GO:0048169 5 5 0,000 0,02803157 0,10250432 ! filopodium assembly GO:0046847 7 5 0,000 0,02803157 0,10230134 GO:0030035|microspike assembly, ! CTP metabolic process GO:0046036 5 5 0,000 0,02803157 0,10209916 GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0006241|CTP biosynthetic process, ! Golgi to endosome transport GO:0006895 5 5 0,000 0,02803157 0,10189778 ! GTP metabolic process GO:0046039 5 5 0,000 0,02803157 0,1016972 ! establishment of tissue polarity GO:0007164 5 5 0,000 0,02803157 0,1014974 ! mRNA stabilization GO:0048255 5 5 0,000 0,02803157 0,10129839 GO:0043489|RNA stabilization, ! positive regulation of cell-cell adhesion GO:0022409 5 5 0,000 0,02803157 0,10110015 ! regulation of neurotransmitter secretion GO:0046928 5 5 0,000 0,02803157 0,10090269 GO:0001956|positive regulation of neurotransmitter secretion, ! neurotransmitter uptake GO:0001504 5 5 0,000 0,02803157 0,100706 ! social behavior GO:0035176 5 5 0,000 0,02803157 0,10051007 ! macrophage chemotaxis GO:0048246 6 5 0,000 0,02803157 0,10031491 ! 2-oxoglutarate metabolic process GO:0006103 5 5 0,000 0,02803157 0,1001205 ! memory GO:0007613 5 5 0,000 0,02803157 0,09992684 ! dopamine receptor signaling pathway GO:0007212 5 5 0,000 0,02803157 0,09973393 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 5 5 0,000 0,02803157 0,09954177 ! membrane hyperpolarization GO:0060081 5 5 0,000 0,02803157 0,09935034 ! response to lipid GO:0033993 5 5 0,000 0,02803157 0,09915965 ! erythrocyte maturation GO:0043249 5 5 0,000 0,02803157 0,09896969 ! hippocampus development GO:0021766 6 5 0,000 0,02803157 0,09878045 ! regulation of carbohydrate biosynthetic process GO:0043255 5 5 0,000 0,02803157 0,09859194 ! glucocorticoid metabolic process GO:0008211 5 5 0,000 0,02803157 0,09840415 ! middle ear morphogenesis GO:0042474 5 5 0,000 0,02803157 0,09821707 ! amyloid precursor protein catabolic process GO:0042987 5 5 0,000 0,02803157 0,0980307 ! mechanosensory behavior GO:0007638 5 5 0,000 0,02803157 0,09784503 ! heart looping GO:0001947 5 5 0,000 0,02803157 0,09766007 ! negative regulation of endocytosis GO:0045806 5 5 0,000 0,02803157 0,09747581 ! response to interferon-gamma GO:0034341 5 5 0,000 0,02803157 0,09729223 ! pseudouridine synthesis GO:0001522 5 5 0,000 0,02803157 0,09710935 ! endocrine pancreas development GO:0031018 5 5 0,000 0,02803157 0,09692716 ! pH reduction GO:0045851 5 5 0,000 0,02803157 0,09674565 GO:0051452|intracellular pH reduction, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 5 5 0,000 0,02803157 0,09656482 ! lipopolysaccharide metabolic process GO:0008653 5 5 0,000 0,02803157 0,09638466 ! positive regulation of chemokine biosynthetic process GO:0045080 5 5 0,000 0,02803157 0,09620517 ! sphingoid biosynthetic process GO:0046520 5 5 0,000 0,02803157 0,09602635 GO:0046513|ceramide biosynthetic process, ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 5 5 0,000 0,02803157 0,09584819 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! thymic T cell selection GO:0045061 5 5 0,000 0,02803157 0,0956707 ! photoreceptor cell maintenance GO:0045494 5 5 0,000 0,02803157 0,09549386 ! adrenal gland development GO:0030325 5 5 0,000 0,02803157 0,09531767 ! regulation of cardiac muscle hypertrophy GO:0010611 5 5 0,000 0,02803157 0,09514213 GO:0010612|regulation of cardiac muscle adaptation, GO:0014743|regulation of muscle hypertrophy, GO:0043502|regulation of muscle adaptation, ! melanocyte differentiation GO:0030318 5 5 0,000 0,02803157 0,09496724 GO:0050931|pigment cell differentiation, ! ovulation GO:0030728 5 5 0,000 0,02803157 0,09479298 ! astrocyte differentiation GO:0048708 5 5 0,000 0,02803157 0,09461937 ! mitochondrial respiratory chain complex assembly GO:0033108 5 5 0,000 0,02803157 0,09444639 GO:0032981|mitochondrial respiratory chain complex I assembly, GO:0010257|NADH dehydrogenase complex assembly, ! pituitary gland development GO:0021983 5 5 0,000 0,02803157 0,09427405 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 5 5 0,000 0,02803157 0,09410233 GO:0033135|regulation of peptidyl-serine phosphorylation, ! tyrosine metabolic process GO:0006570 5 5 0,000 0,02803157 0,09393123 ! cytoskeletal anchoring at plasma membrane GO:0007016 6 5 0,000 0,02803157 0,09376076 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 5 5 0,000 0,02803157 0,0935909 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, GO:0009164|nucleoside catabolic process, ! microtubule nucleation GO:0007020 5 5 0,000 0,02803157 0,09342166 ! regulation of interleukin-6 biosynthetic process GO:0045408 5 5 0,000 0,02803157 0,09325303 ! regulation of interleukin-8 biosynthetic process GO:0045414 5 5 0,000 0,02803157 0,093085 ! indolalkylamine metabolic process GO:0006586 5 5 0,000 0,02803157 0,09291758 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! muscle cell migration GO:0014812 5 5 0,000 0,02803157 0,09275077 ! phasic smooth muscle contraction GO:0014821 5 5 0,000 0,02803157 0,09258455 ! central nervous system neuron axonogenesis GO:0021955 6 5 0,000 0,02803157 0,09241892 GO:0021952|central nervous system projection neuron axonogenesis, ! sister chromatid cohesion GO:0007062 5 5 0,000 0,02803157 0,09225389 ! response to ATP GO:0033198 5 5 0,000 0,02803157 0,09208944 ! regulation of type I interferon production GO:0032479 5 5 0,000 0,02803157 0,09192558 ! regulation of appetite GO:0032098 5 5 0,000 0,02803157 0,0917623 GO:0032095|regulation of response to food, ! vesicle fusion GO:0006906 5 5 0,000 0,02803157 0,0915996 ! paraxial mesoderm development GO:0048339 5 5 0,000 0,02803157 0,09143748 ! regulation of the force of heart contraction GO:0002026 5 5 0,000 0,02803157 0,09127593 ! maintenance of protein location in nucleus GO:0051457 5 5 0,000 0,02803157 0,09111495 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,02803157 0,09095454 ! receptor clustering GO:0043113 5 5 0,000 0,02803157 0,09079469 ! neurotransmitter biosynthetic process GO:0042136 6 5 0,000 0,02803157 0,0906354 ! actin cytoskeleton reorganization GO:0031532 5 5 0,000 0,02803157 0,09047667 ! lens development in camera-type eye GO:0002088 5 5 0,000 0,02803157 0,09031849 ! retinol metabolic process GO:0042572 5 5 0,000 0,02803157 0,09016087 ! corticosteroid receptor signaling pathway GO:0031958 5 5 0,000 0,02803157 0,09000379 GO:0042921|glucocorticoid receptor signaling pathway, ! temperature homeostasis GO:0001659 5 5 0,000 0,02803157 0,08984726 ! positive regulation of exocytosis GO:0045921 6 5 0,000 0,02803157 0,08969128 ! parturition GO:0007567 5 5 0,000 0,02803157 0,08953583 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,02803157 0,08938093 ! regulation of vascular endothelial growth factor production GO:0010574 5 5 0,000 0,02803157 0,08922656 ! Schwann cell differentiation GO:0014037 5 5 0,000 0,02803157 0,08907272 ! acyl-CoA metabolic process GO:0006637 5 5 0,000 0,02803157 0,08891941 ! wound healing, spreading of epidermal cells GO:0035313 5 5 0,000 0,02803157 0,08876663 ! regulation of gliogenesis GO:0014013 5 5 0,000 0,02803157 0,08861437 GO:0045685|regulation of glial cell differentiation, ! positive regulation of peptide secretion GO:0002793 5 5 0,000 0,02803157 0,08846263 ! oligodendrocyte development GO:0014003 5 5 0,000 0,02803157 0,08831141 ! hyaluronan metabolic process GO:0030212 5 5 0,000 0,02803157 0,08816071 ! activated T cell proliferation GO:0050798 5 5 0,000 0,02803157 0,08801052 ! interaction with symbiont GO:0051702 5 5 0,000 0,02803157 0,08786084 ! cellular extravasation GO:0045123 5 5 0,000 0,02803157 0,08771168 ! positive regulation of axonogenesis GO:0050772 5 5 0,000 0,02803157 0,08756301 ! peptidyl-asparagine modification GO:0018196 5 5 0,000 0,02803157 0,08741485 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! positive regulation of phagocytosis GO:0050766 5 5 0,000 0,02803157 0,08726719 ! regulation of insulin receptor signaling pathway GO:0046626 5 5 0,000 0,02803157 0,08712003 ! antigen processing and presentation of exogenous antigen GO:0019884 5 5 0,000 0,02803157 0,08697336 ! response to amine stimulus GO:0014075 5 5 0,000 0,02803157 0,08682719 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 5 5 0,000 0,02803157 0,0866815 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 5 5 0,000 0,02803157 0,08653631 ! synaptic vesicle exocytosis GO:0016079 6 5 0,000 0,02803157 0,0863916 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 5 5 0,000 0,02803157 0,08624737 ! glycosylceramide metabolic process GO:0006677 5 5 0,000 0,02803157 0,08610363 ! neuron recognition GO:0008038 5 5 0,000 0,02803157 0,08596036 ! negative regulation of focal adhesion formation GO:0051895 6 5 0,000 0,02803157 0,08581757 ! decidualization GO:0046697 5 5 0,000 0,02803157 0,08567525 ! hair follicle maturation GO:0048820 5 5 0,000 0,02803157 0,08553341 ! phosphatidylinositol biosynthetic process GO:0006661 5 5 0,000 0,02803157 0,08539203 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 0,02803157 0,08525112 GO:0009155|purine deoxyribonucleotide catabolic process, ! regulation of interleukin-12 production GO:0032655 5 5 0,000 0,02803157 0,08511067 ! positive regulation of interleukin-6 production GO:0032755 5 5 0,000 0,02803157 0,08497069 ! positive regulation of monooxygenase activity GO:0032770 5 5 0,000 0,02803157 0,08483116 ! postreplication repair GO:0006301 5 5 0,000 0,02803157 0,08469209 ! spinal cord motor neuron differentiation GO:0021522 5 5 0,000 0,02803157 0,08455348 GO:0021517|ventral spinal cord development, ! histone methylation GO:0016571 5 5 0,000 0,02803157 0,08441532 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,02803157 0,08427761 ! positive regulation of immunoglobulin mediated immune response GO:0002891 5 5 0,000 0,02803157 0,08414035 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of interferon-gamma production GO:0032729 5 5 0,000 0,02803157 0,08400354 ! negative regulation of tumor necrosis factor production GO:0032720 5 5 0,000 0,02803157 0,08386717 ! intracellular cholesterol transport GO:0032367 5 5 0,000 0,02803157 0,08373124 GO:0032366|intracellular sterol transport, ! regulation of mast cell activation GO:0033003 5 5 0,000 0,02803157 0,08359576 ! morphogenesis of a polarized epithelium GO:0001738 5 5 0,000 0,02803157 0,08346071 ! regulation of hormone metabolic process GO:0032350 5 5 0,000 0,02803157 0,08332609 ! regulation of transcription from RNA polymerase III promoter GO:0006359 5 5 0,000 0,02803157 0,08319191 ! regulation of inflammatory response to antigenic stimulus GO:0002861 5 5 0,000 0,02803157 0,08305816 ! sterol catabolic process GO:0016127 5 5 0,000 0,02803157 0,08292484 GO:0006707|cholesterol catabolic process, ! negative regulation of oxidoreductase activity GO:0051354 5 5 0,000 0,02803157 0,08279195 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 5 5 0,000 0,02803157 0,08265948 ! detection of biotic stimulus GO:0009595 5 5 0,000 0,02803157 0,08252744 ! regulation of immune response to tumor cell GO:0002837 5 5 0,000 0,02803157 0,08239582 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 5 5 0,000 0,02803157 0,08226461 ! zymogen activation GO:0031638 5 5 0,000 0,02803157 0,08213383 ! positive regulation of interleukin-1 beta secretion GO:0050718 5 5 0,000 0,02803157 0,08200346 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 5 5 0,000 0,02803157 0,0818735 GO:0002820|negative regulation of adaptive immune response, ! cellular response to nutrient GO:0031670 5 5 0,000 0,02803157 0,08174395 ! peptidyl-histidine modification GO:0018202 5 5 0,000 0,02803157 0,08161481 ! nucleosome positioning GO:0016584 5 5 0,000 0,02803157 0,08148608 ! regulation of isotype switching GO:0045191 5 5 0,000 0,02803157 0,08135776 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 5 5 0,000 0,02803157 0,08122984 ! negative regulation of neurological system process GO:0031645 5 5 0,000 0,02803157 0,08110232 ! regulation of myoblast differentiation GO:0045661 5 5 0,000 0,02803157 0,0809752 ! glutathione biosynthetic process GO:0006750 5 5 0,000 0,02803157 0,08084848 ! NADPH regeneration GO:0006740 5 5 0,000 0,02803157 0,08072215 GO:0006098|pentose-phosphate shunt, ! positive regulation of erythrocyte differentiation GO:0045648 5 5 0,000 0,02803157 0,08059622 ! positive regulation of epidermis development GO:0045684 5 5 0,000 0,02803157 0,08047068 ! positive regulation of leukocyte chemotaxis GO:0002690 5 5 0,000 0,02803157 0,08034553 GO:0002688|regulation of leukocyte chemotaxis, ! musculoskeletal movement GO:0050881 5 5 0,000 0,02803157 0,08022077 GO:0050879|multicellular organismal movement, ! neuromuscular process controlling posture GO:0050884 5 5 0,000 0,02803157 0,0800964 ! sarcomere organization GO:0045214 5 5 0,000 0,02803157 0,07997241 ! regulation of epidermal cell differentiation GO:0045604 5 5 0,000 0,02803157 0,0798488 ! activation of NF-kappaB-inducing kinase activity GO:0007250 5 5 0,000 0,02803157 0,07972558 ! negative regulation of glucose transport GO:0010829 5 5 0,000 0,02803157 0,07960274 GO:0046325|negative regulation of glucose import, ! positive regulation of T-helper cell differentiation GO:0045624 5 5 0,000 0,02803157 0,07948027 GO:0045622|regulation of T-helper cell differentiation, ! dopamine biosynthetic process GO:0042416 5 5 0,000 0,02803157 0,07935818 ! male genitalia development GO:0030539 5 5 0,000 0,02803157 0,07923647 ! nicotinamide nucleotide biosynthetic process GO:0019359 5 5 0,000 0,02803157 0,07911513 ! quaternary ammonium group transport GO:0015697 5 5 0,000 0,02803157 0,07899415 ! thyroid hormone metabolic process GO:0042403 5 5 0,000 0,02803157 0,07887355 ! leukocyte mediated cytotoxicity GO:0001909 5 5 0,000 0,02803157 0,07875332 ! positive regulation of viral reproduction GO:0048524 5 5 0,000 0,02803157 0,07863345 ! removal of superoxide radicals GO:0019430 6 5 0,000 0,02803157 0,07851395 ! myeloid cell homeostasis GO:0002262 5 5 0,000 0,02803157 0,07839481 ! regulation of fatty acid oxidation GO:0046320 5 5 0,000 0,02803157 0,07827603 ! regulation of Rac protein signal transduction GO:0035020 5 5 0,000 0,02803157 0,0781576 ! ATP catabolic process GO:0006200 5 5 0,000 0,02803157 0,07803954 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,02803157 0,07792184 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 5 5 0,000 0,02803157 0,07780448 ! blastocyst formation GO:0001825 5 5 0,000 0,02803157 0,07768748 ! regulation of fibrinolysis GO:0051917 5 5 0,000 0,02803157 0,07757084 ! embryonic gut development GO:0048566 5 5 0,000 0,02803157 0,07745454 ! negative regulation of organic acid transport GO:0032891 5 5 0,000 0,02803157 0,07733859 ! pyrimidine base metabolic process GO:0006206 5 5 0,000 0,02803157 0,07722298 ! activation of innate immune response GO:0002218 5 5 0,000 0,02803157 0,07710773 GO:0002758|innate immune response-activating signal transduction, ! positive regulation of blood vessel endothelial cell migration GO:0043536 5 5 0,000 0,02803157 0,07699281 ! catecholamine transport GO:0051937 5 5 0,000 0,02803157 0,07687824 ! negative regulation of blood vessel endothelial cell migration GO:0043537 5 5 0,000 0,02803157 0,07676401 ! regulation of NF-kappaB import into nucleus GO:0042345 5 5 0,000 0,02803157 0,07665011 ! muscle adaptation GO:0043500 5 5 0,000 0,02803157 0,07653656 ! positive regulation of actin filament bundle formation GO:0032233 5 5 0,000 0,02803157 0,07642334 ! embryonic heart tube development GO:0035050 5 5 0,000 0,02803157 0,07631045 ! cardiac cell differentiation GO:0035051 6 5 0,000 0,02803157 0,0761979 ! defense response to fungus GO:0050832 5 5 0,000 0,02803157 0,07608568 ! lysogeny GO:0030069 5 5 0,000 0,02803157 0,07597379 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 5 5 0,000 0,02803157 0,07586223 ! B cell receptor signaling pathway GO:0050853 5 5 0,000 0,02803157 0,07575099 ! positive regulation of smooth muscle contraction GO:0045987 5 5 0,000 0,02803157 0,07564008 ! establishment of cell polarity GO:0030010 5 5 0,000 0,02803157 0,0755295 ! mitochondrion localization GO:0051646 5 5 0,000 0,02803157 0,07541924 ! nucleus localization GO:0051647 5 5 0,000 0,02803157 0,0753093 ! regulation of synapse structure and activity GO:0050803 5 5 0,000 0,02803157 0,07519967 ! sex differentiation GO:0007548 47 47 1,000 0,02883271 0,07723646 ! rhythmic process GO:0048511 47 47 1,000 0,02883271 0,07712436 ! regulation of catabolic process GO:0009894 48 47 1,000 0,02883271 0,07701259 ! actin filament organization GO:0007015 50 48 1,000 0,02998012 0,07996145 ! regulation of ubiquitin-protein ligase activity GO:0051438 49 48 1,000 0,02998012 0,0798459 ! protein localization in nucleus GO:0034504 48 48 1,000 0,02998012 0,07973068 ! ossification GO:0001503 50 49 1,000 0,0311456 0,08271086 GO:0060348|bone development, ! cellular lipid catabolic process GO:0044242 50 49 1,000 0,0311456 0,08259185 ! response to nutrient GO:0007584 49 49 1,000 0,0311456 0,08247318 ! regulation of ligase activity GO:0051340 50 49 1,000 0,0311456 0,08235486 ! negative regulation of transport GO:0051051 51 50 1,000 0,03232891 0,08536129 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 50 50 1,000 0,03232891 0,08523917 ! transcription initiation GO:0006352 50 50 1,000 0,03232891 0,0851174 ! anterior/posterior pattern formation GO:0009952 51 50 1,000 0,03232891 0,08499598 ! protein modification by small protein conjugation GO:0032446 52 51 1,000 0,03352983 0,08802775 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 6 6 0,000 0,03354528 0,08794303 ! axon extension GO:0048675 7 6 0,000 0,03354528 0,08781811 ! oligosaccharide biosynthetic process GO:0009312 6 6 0,000 0,03354528 0,08769354 ! tRNA modification GO:0006400 6 6 0,000 0,03354528 0,08756933 ! somatic diversification of immune receptors via somatic mutation GO:0002566 6 6 0,000 0,03354528 0,08744547 GO:0016446|somatic hypermutation of immunoglobulin genes, ! 'de novo' posttranslational protein folding GO:0051084 6 6 0,000 0,03354528 0,08732196 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 6 6 0,000 0,03354528 0,0871988 ! negative regulation of cellular catabolic process GO:0031330 6 6 0,000 0,03354528 0,08707598 ! regulation of S phase GO:0033261 6 6 0,000 0,03354528 0,08695351 ! myotube differentiation GO:0014902 6 6 0,000 0,03354528 0,08683139 ! regulation of B cell proliferation GO:0030888 6 6 0,000 0,03354528 0,0867096 ! bone remodeling GO:0046849 6 6 0,000 0,03354528 0,08658816 ! N-glycan processing GO:0006491 6 6 0,000 0,03354528 0,08646706 ! glycosaminoglycan catabolic process GO:0006027 6 6 0,000 0,03354528 0,0863463 ! negative regulation of JAK-STAT cascade GO:0046426 6 6 0,000 0,03354528 0,08622587 ! retina development in camera-type eye GO:0060041 6 6 0,000 0,03354528 0,08610578 ! RNA methylation GO:0001510 6 6 0,000 0,03354528 0,08598602 ! cartilage condensation GO:0001502 7 6 0,000 0,03354528 0,08586659 ! regulation of activated T cell proliferation GO:0046006 6 6 0,000 0,03354528 0,0857475 ! regulation of positive chemotaxis GO:0050926 6 6 0,000 0,03354528 0,08562874 GO:0050927|positive regulation of positive chemotaxis, ! succinate metabolic process GO:0006105 7 6 0,000 0,03354528 0,0855103 ! artery development GO:0060840 6 6 0,000 0,03354528 0,08539219 GO:0048844|artery morphogenesis, ! positive regulation of neurotransmitter transport GO:0051590 6 6 0,000 0,03354528 0,08527441 ! bile acid metabolic process GO:0008206 6 6 0,000 0,03354528 0,08515695 ! androgen metabolic process GO:0008209 6 6 0,000 0,03354528 0,08503982 ! estrogen metabolic process GO:0008210 6 6 0,000 0,03354528 0,084923 ! limbic system development GO:0021761 7 6 0,000 0,03354528 0,08480651 ! cytoplasmic sequestering of transcription factor GO:0042994 6 6 0,000 0,03354528 0,08469034 ! positive regulation of transcription factor import into nucleus GO:0042993 6 6 0,000 0,03354528 0,08457448 ! positive regulation of heart contraction GO:0045823 6 6 0,000 0,03354528 0,08445894 ! positive regulation of gene expression, epigenetic GO:0045815 6 6 0,000 0,03354528 0,08434372 ! negative regulation of protein amino acid phosphorylation GO:0001933 6 6 0,000 0,03354528 0,08422881 ! positive regulation of cell growth GO:0030307 6 6 0,000 0,03354528 0,08411421 ! ribonucleoside triphosphate catabolic process GO:0009203 6 6 0,000 0,03354528 0,08399993 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! regulation of chemokine biosynthetic process GO:0045073 6 6 0,000 0,03354528 0,08388595 ! inositol phosphate-mediated signaling GO:0048016 6 6 0,000 0,03354528 0,08377229 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 6 6 0,000 0,03354528 0,08365893 ! arginine metabolic process GO:0006525 6 6 0,000 0,03354528 0,08354588 GO:0006527|arginine catabolic process, ! regulation of catecholamine secretion GO:0050433 6 6 0,000 0,03354528 0,08343313 ! glutamate catabolic process GO:0006538 7 6 0,000 0,03354528 0,08332068 ! L-phenylalanine metabolic process GO:0006558 6 6 0,000 0,03354528 0,08320854 GO:0006559|L-phenylalanine catabolic process, ! glucan biosynthetic process GO:0009250 6 6 0,000 0,03354528 0,0830967 GO:0005978|glycogen biosynthetic process, ! V(D)J recombination GO:0033151 6 6 0,000 0,03354528 0,08298516 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 0,03354528 0,08287392 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 6 6 0,000 0,03354528 0,08276298 ! negative regulation of endothelial cell migration GO:0010596 6 6 0,000 0,03354528 0,08265234 ! regulation of heart rate GO:0002027 6 6 0,000 0,03354528 0,08254199 ! lipid digestion GO:0044241 6 6 0,000 0,03354528 0,08243193 ! asymmetric protein localization GO:0008105 6 6 0,000 0,03354528 0,08232217 ! retrograde transport, endosome to Golgi GO:0042147 6 6 0,000 0,03354528 0,0822127 ! phagocytosis, engulfment GO:0006911 6 6 0,000 0,03354528 0,08210352 ! Rac protein signal transduction GO:0016601 6 6 0,000 0,03354528 0,08199463 ! regulation of vascular permeability GO:0043114 6 6 0,000 0,03354528 0,08188602 ! regulation of calcium ion transport into cytosol GO:0010522 6 6 0,000 0,03354528 0,08177771 ! ruffle organization GO:0031529 6 6 0,000 0,03354528 0,08166968 ! preassembly of GPI anchor in ER membrane GO:0016254 6 6 0,000 0,03354528 0,08156194 ! retinoic acid metabolic process GO:0042573 6 6 0,000 0,03354528 0,08145448 ! neutral amino acid transport GO:0015804 6 6 0,000 0,03354528 0,0813473 ! L-amino acid transport GO:0015807 6 6 0,000 0,03354528 0,0812404 ! bone mineralization GO:0030282 6 6 0,000 0,03354528 0,08113379 GO:0031214|biomineral formation, ! rRNA modification GO:0000154 6 6 0,000 0,03354528 0,08102745 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 6 6 0,000 0,03354528 0,0809214 GO:0002717|positive regulation of natural killer cell mediated immunity, GO:0002715|regulation of natural killer cell mediated immunity, GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of bone resorption GO:0045124 6 6 0,000 0,03354528 0,08081562 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 7 6 0,000 0,03354528 0,08071011 ! purine base biosynthetic process GO:0009113 6 6 0,000 0,03354528 0,08060489 ! negative regulation of axonogenesis GO:0050771 7 6 0,000 0,03354528 0,08049993 ! regulation of phagocytosis GO:0050764 6 6 0,000 0,03354528 0,08039525 ! regulation of organ growth GO:0046620 6 6 0,000 0,03354528 0,08029084 ! regulation of circadian rhythm GO:0042752 6 6 0,000 0,03354528 0,0801867 ! positive regulation of T cell mediated immunity GO:0002711 6 6 0,000 0,03354528 0,08008283 ! response to dsRNA GO:0043331 6 6 0,000 0,03354528 0,07997923 ! DNA unwinding during replication GO:0006268 6 6 0,000 0,03354528 0,0798759 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 6 6 0,000 0,03354528 0,07977284 GO:0009147|pyrimidine nucleoside triphosphate metabolic process, ! genitalia development GO:0048806 6 6 0,000 0,03354528 0,07967004 ! sphingomyelin metabolic process GO:0006684 6 6 0,000 0,03354528 0,0795675 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 6 6 0,000 0,03354528 0,07946523 ! positive regulation of B cell differentiation GO:0045579 6 6 0,000 0,03354528 0,07936322 ! multicellular organismal aging GO:0010259 6 6 0,000 0,03354528 0,07926147 ! regulation of focal adhesion formation GO:0051893 7 6 0,000 0,03354528 0,07915998 ! respiratory chain complex IV assembly GO:0008535 6 6 0,000 0,03354528 0,07905876 ! erythrocyte development GO:0048821 6 6 0,000 0,03354528 0,07895779 ! renal water homeostasis GO:0003091 6 6 0,000 0,03354528 0,07885708 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 6 6 0,000 0,03354528 0,07875662 GO:0043372|positive regulation of CD4-positive, alpha beta T cell differentiation, ! ribosomal large subunit biogenesis GO:0042273 6 6 0,000 0,03354528 0,07865642 ! regulation of Rho GTPase activity GO:0032319 6 6 0,000 0,03354528 0,07855648 ! ribosome assembly GO:0042255 6 6 0,000 0,03354528 0,07845679 ! positive regulation of Ras GTPase activity GO:0032320 6 6 0,000 0,03354528 0,07835735 ! diencephalon development GO:0021536 6 6 0,000 0,03354528 0,07825816 ! fucose catabolic process GO:0019317 6 6 0,000 0,03354528 0,07815923 GO:0042355|L-fucose catabolic process, ! nitric oxide metabolic process GO:0046209 6 6 0,000 0,03354528 0,07806054 GO:0006809|nitric oxide biosynthetic process, ! regulation of lipid transport GO:0032368 6 6 0,000 0,03354528 0,0779621 ! regulation of cell division GO:0051302 6 6 0,000 0,03354528 0,07786391 ! positive regulation of interleukin-1 secretion GO:0050716 6 6 0,000 0,03354528 0,07776597 ! cellular metabolic compound salvage GO:0043094 6 6 0,000 0,03354528 0,07766828 ! regulation of T-helper 2 type immune response GO:0002828 6 6 0,000 0,03354528 0,07757083 ! salivary gland morphogenesis GO:0007435 6 6 0,000 0,03354528 0,07747362 ! neuroblast proliferation GO:0007405 6 6 0,000 0,03354528 0,07737666 ! regulation of interleukin-1 beta secretion GO:0050706 6 6 0,000 0,03354528 0,07727993 ! nitric oxide mediated signal transduction GO:0007263 6 6 0,000 0,03354528 0,07718346 ! regulation of glucose transport GO:0010827 6 6 0,000 0,03354528 0,07708722 GO:0046324|regulation of glucose import, ! intestinal absorption GO:0050892 6 6 0,000 0,03354528 0,07699122 ! methionine biosynthetic process GO:0009086 6 6 0,000 0,03354528 0,07689546 ! glutamine family amino acid biosynthetic process GO:0009084 6 6 0,000 0,03354528 0,07679993 ! lymph node development GO:0048535 6 6 0,000 0,03354528 0,07670465 ! organic cation transport GO:0015695 6 6 0,000 0,03354528 0,0766096 ! negative regulation of BMP signaling pathway GO:0030514 6 6 0,000 0,03354528 0,07651479 ! regulation of RNA splicing GO:0043484 6 6 0,000 0,03354528 0,07642021 ! positive regulation of JNK cascade GO:0046330 7 6 0,000 0,03354528 0,07632586 ! sperm-egg recognition GO:0035036 7 6 0,000 0,03354528 0,07623175 GO:0007339|binding of sperm to zona pellucida, ! germ cell migration GO:0008354 6 6 0,000 0,03354528 0,07613787 ! establishment or maintenance of apical/basal cell polarity GO:0035088 6 6 0,000 0,03354528 0,07604422 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 6 6 0,000 0,03354528 0,0759508 ! alditol metabolic process GO:0019400 6 6 0,000 0,03354528 0,0758576 ! regulation of synaptic transmission, GABAergic GO:0032228 6 6 0,000 0,03354528 0,07576464 ! regulation of amino acid transport GO:0051955 6 6 0,000 0,03354528 0,07567191 ! maternal placenta development GO:0001893 6 6 0,000 0,03354528 0,0755794 ! negative regulation of immune effector process GO:0002698 6 6 0,000 0,03354528 0,07548712 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 52 52 1,000 0,03474813 0,07809855 ! regulation of body fluid levels GO:0050878 55 52 1,000 0,03474813 0,07800342 ! carbohydrate biosynthetic process GO:0016051 53 53 1,000 0,03598359 0,08067854 ! carbohydrate catabolic process GO:0016052 53 53 1,000 0,03598359 0,08058051 ! regulation of T cell activation GO:0050863 53 53 1,000 0,03598359 0,08048272 ! response to virus GO:0009615 54 54 1,000 0,03723599 0,08318294 ! hormone metabolic process GO:0042445 55 54 1,000 0,03723599 0,08308223 ! negative regulation of multicellular organismal process GO:0051241 55 54 1,000 0,03723599 0,08298177 ! microtubule cytoskeleton organization GO:0000226 55 55 1,000 0,03850509 0,08570639 ! protein modification by small protein conjugation or removal GO:0070647 56 55 1,000 0,03850509 0,085603 ! respiratory burst GO:0045730 7 7 0,000 0,03902851 0,0866621 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 7 7 0,000 0,03902851 0,08655781 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 7 7 0,000 0,03902851 0,08645378 ! negative regulation of cell projection organization GO:0031345 8 7 0,000 0,03902851 0,08634999 ! positive regulation of blood pressure GO:0045777 7 7 0,000 0,03902851 0,08624646 ! pteridine and derivative biosynthetic process GO:0042559 7 7 0,000 0,03902851 0,08614317 ! regulation of chemokine production GO:0032642 7 7 0,000 0,03902851 0,08604012 ! double-strand break repair via homologous recombination GO:0000724 7 7 0,000 0,03902851 0,08593733 GO:0000725|recombinational repair, ! positive regulation of GTPase activity GO:0043547 7 7 0,000 0,03902851 0,08583478 ! SMAD protein nuclear translocation GO:0007184 7 7 0,000 0,03902851 0,08573247 ! cellular protein complex disassembly GO:0043624 8 7 0,000 0,03902851 0,08563041 GO:0043241|protein complex disassembly, ! gene silencing by RNA GO:0031047 7 7 0,000 0,03902851 0,08552859 ! regulation of receptor-mediated endocytosis GO:0048259 7 7 0,000 0,03902851 0,08542701 ! regulation of neurotransmitter transport GO:0051588 7 7 0,000 0,03902851 0,08532567 ! keratinocyte proliferation GO:0043616 7 7 0,000 0,03902851 0,08522458 ! axis specification GO:0009798 7 7 0,000 0,03902851 0,08512372 ! negative regulation of muscle cell differentiation GO:0051148 7 7 0,000 0,03902851 0,0850231 ! visual behavior GO:0007632 7 7 0,000 0,03902851 0,08492272 GO:0008542|visual learning, ! startle response GO:0001964 7 7 0,000 0,03902851 0,08482257 ! amyloid precursor protein metabolic process GO:0042982 7 7 0,000 0,03902851 0,08472267 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 8 7 0,000 0,03902851 0,08462299 ! positive regulation of lipid metabolic process GO:0045834 7 7 0,000 0,03902851 0,08452355 ! negative regulation of lipid metabolic process GO:0045833 7 7 0,000 0,03902851 0,08442435 ! regulation of interferon-gamma biosynthetic process GO:0045072 7 7 0,000 0,03902851 0,08432537 ! endothelial cell differentiation GO:0045446 7 7 0,000 0,03902851 0,08422663 ! negative regulation of striated muscle development GO:0045843 7 7 0,000 0,03902851 0,08412812 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 7 7 0,000 0,03902851 0,08402984 ! hemoglobin metabolic process GO:0020027 7 7 0,000 0,03902851 0,08393179 ! regulation of exit from mitosis GO:0007096 7 7 0,000 0,03902851 0,08383397 ! protein targeting to ER GO:0045047 8 7 0,000 0,03902851 0,08373637 ! cell differentiation in spinal cord GO:0021515 7 7 0,000 0,03902851 0,083639 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 7 7 0,000 0,03902851 0,08354186 ! endoderm development GO:0007492 7 7 0,000 0,03902851 0,08344495 ! regulation of defense response to virus GO:0050688 7 7 0,000 0,03902851 0,08334825 ! glycolipid biosynthetic process GO:0009247 7 7 0,000 0,03902851 0,08325179 GO:0006688|glycosphingolipid biosynthetic process, ! regulation of mRNA processing GO:0050684 7 7 0,000 0,03902851 0,08315554 ! response to hexose stimulus GO:0009746 7 7 0,000 0,03902851 0,08305952 GO:0034284|response to monosaccharide stimulus, GO:0009749|response to glucose stimulus, ! membrane protein ectodomain proteolysis GO:0006509 7 7 0,000 0,03902851 0,08296372 GO:0033619|membrane protein proteolysis, ! positive regulation of survival gene product expression GO:0045885 7 7 0,000 0,03902851 0,08286814 ! cardiac muscle tissue development GO:0048738 7 7 0,000 0,03902851 0,08277278 ! nucleotide-sugar metabolic process GO:0009225 7 7 0,000 0,03902851 0,08267764 ! complement activation, alternative pathway GO:0006957 7 7 0,000 0,03902851 0,08258271 ! arachidonic acid secretion GO:0050482 7 7 0,000 0,03902851 0,08248801 GO:0032309|icosanoid secretion, ! polyamine biosynthetic process GO:0006596 7 7 0,000 0,03902851 0,08239352 ! UV protection GO:0009650 7 7 0,000 0,03902851 0,08229925 ! DNA integration GO:0015074 7 7 0,000 0,03902851 0,08220519 ! myofibril assembly GO:0030239 7 7 0,000 0,03902851 0,08211135 GO:0055002|striated muscle cell development, ! positive regulation of muscle contraction GO:0045933 7 7 0,000 0,03902851 0,08201772 ! negative regulation of muscle contraction GO:0045932 7 7 0,000 0,03902851 0,08192431 ! chondroitin sulfate biosynthetic process GO:0030206 7 7 0,000 0,03902851 0,08183111 GO:0030204|chondroitin sulfate metabolic process, ! regulation of exocytosis GO:0017157 8 7 0,000 0,03902851 0,08173812 ! phosphatidylcholine biosynthetic process GO:0006656 7 7 0,000 0,03902851 0,08164534 ! heparan sulfate proteoglycan metabolic process GO:0030201 7 7 0,000 0,03902851 0,08155277 GO:0015012|heparan sulfate proteoglycan biosynthetic process, ! stem cell development GO:0048864 7 7 0,000 0,03902851 0,08146041 GO:0019827|stem cell maintenance, ! negative regulation of myeloid leukocyte differentiation GO:0002762 7 7 0,000 0,03902851 0,08136826 ! NLS-bearing substrate import into nucleus GO:0006607 7 7 0,000 0,03902851 0,08127632 ! axon cargo transport GO:0008088 7 7 0,000 0,03902851 0,08118459 ! eating behavior GO:0042755 7 7 0,000 0,03902851 0,08109306 ! purine nucleoside triphosphate catabolic process GO:0009146 7 7 0,000 0,03902851 0,08100174 ! regulation of interleukin-8 production GO:0032677 7 7 0,000 0,03902851 0,08091062 ! purine ribonucleotide catabolic process GO:0009154 7 7 0,000 0,03902851 0,08081971 ! ribosomal small subunit biogenesis GO:0042274 7 7 0,000 0,03902851 0,08072901 ! cranial nerve development GO:0021545 7 7 0,000 0,03902851 0,0806385 ! protein import into peroxisome matrix GO:0016558 7 7 0,000 0,03902851 0,0805482 ! induction of an organ GO:0001759 7 7 0,000 0,03902851 0,0804581 ! leukocyte activation during immune response GO:0002366 7 7 0,000 0,03902851 0,08036821 GO:0002263|cell activation during immune response, ! response to estradiol stimulus GO:0032355 7 7 0,000 0,03902851 0,08027851 ! autonomic nervous system development GO:0048483 7 7 0,000 0,03902851 0,08018901 ! intracellular lipid transport GO:0032365 7 7 0,000 0,03902851 0,08009971 ! detection of chemical stimulus GO:0009593 8 7 0,000 0,03902851 0,08001062 ! platelet activation GO:0030168 8 7 0,000 0,03902851 0,07992172 ! negative regulation of cytokine secretion GO:0050710 7 7 0,000 0,03902851 0,07983301 ! regulation of interleukin-1 secretion GO:0050704 7 7 0,000 0,03902851 0,07974451 ! natural killer cell activation GO:0030101 7 7 0,000 0,03902851 0,07965619 ! NADP metabolic process GO:0006739 7 7 0,000 0,03902851 0,07956808 ! neuromuscular synaptic transmission GO:0007274 7 7 0,000 0,03902851 0,07948016 ! synaptic transmission, cholinergic GO:0007271 7 7 0,000 0,03902851 0,07939243 ! ubiquinone metabolic process GO:0006743 7 7 0,000 0,03902851 0,0793049 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, GO:0042375|quinone cofactor metabolic process, ! positive regulation of acute inflammatory response GO:0002675 7 7 0,000 0,03902851 0,07921756 ! regulation of osteoclast differentiation GO:0045670 7 7 0,000 0,03902851 0,07913041 ! negative regulation of cell-substrate adhesion GO:0010812 8 7 0,000 0,03902851 0,07904345 GO:0001953|negative regulation of cell-matrix adhesion, ! multicellular organismal water homeostasis GO:0050891 7 7 0,000 0,03902851 0,07895669 ! regulation of ATPase activity GO:0043462 7 7 0,000 0,03902851 0,07887011 ! cell-cell recognition GO:0009988 8 7 0,000 0,03902851 0,07878373 ! hormone catabolic process GO:0042447 7 7 0,000 0,03902851 0,07869753 ! dopamine metabolic process GO:0042417 7 7 0,000 0,03902851 0,07861152 ! cAMP biosynthetic process GO:0006171 7 7 0,000 0,03902851 0,0785257 ! oxygen transport GO:0015671 7 7 0,000 0,03902851 0,07844007 ! pyridine nucleotide biosynthetic process GO:0019363 7 7 0,000 0,03902851 0,07835462 ! regulation of mRNA stability GO:0043488 7 7 0,000 0,03902851 0,07826936 ! biogenic amine catabolic process GO:0042402 7 7 0,000 0,03902851 0,07818429 ! regulation of axon extension GO:0030516 7 7 0,000 0,03902851 0,0780994 ! cell killing GO:0001906 7 7 0,000 0,03902851 0,07801469 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 7 7 0,000 0,03902851 0,07793017 ! adult feeding behavior GO:0008343 7 7 0,000 0,03902851 0,07784583 ! pyrimidine nucleotide catabolic process GO:0006244 7 7 0,000 0,03902851 0,07776167 ! positive regulation of protein polymerization GO:0032273 7 7 0,000 0,03902851 0,07767769 ! T cell receptor signaling pathway GO:0050852 7 7 0,000 0,03902851 0,0775939 ! response to cold GO:0009409 7 7 0,000 0,03902851 0,07751028 ! extracellular structure organization GO:0043062 56 56 1,000 0,0397907 0,07893892 ! protein localization in organelle GO:0033365 59 59 1,000 0,04374431 0,08668899 ! immune effector process GO:0002252 59 59 1,000 0,04374431 0,08659587 ! negative regulation of muscle development GO:0048635 8 8 0,000 0,04448143 0,08796059 ! very-long-chain fatty acid metabolic process GO:0000038 8 8 0,000 0,04448143 0,08786631 ! positive regulation of translation GO:0045727 8 8 0,000 0,04448143 0,08777223 ! positive regulation of cell killing GO:0031343 8 8 0,000 0,04448143 0,08767836 ! superoxide anion generation GO:0042554 8 8 0,000 0,04448143 0,08758469 ! sulfur amino acid biosynthetic process GO:0000097 8 8 0,000 0,04448143 0,08749121 ! cGMP metabolic process GO:0046068 8 8 0,000 0,04448143 0,08739794 GO:0006182|cGMP biosynthetic process, ! thyroid gland development GO:0030878 8 8 0,000 0,04448143 0,08730486 ! 'de novo' protein folding GO:0006458 8 8 0,000 0,04448143 0,08721199 ! dicarboxylic acid transport GO:0006835 8 8 0,000 0,04448143 0,08711931 ! phosphoinositide phosphorylation GO:0046854 8 8 0,000 0,04448143 0,08702682 ! embryonic hindlimb morphogenesis GO:0035116 8 8 0,000 0,04448143 0,08693454 ! zinc ion transport GO:0006829 8 8 0,000 0,04448143 0,08684244 ! embryonic forelimb morphogenesis GO:0035115 8 8 0,000 0,04448143 0,08675055 ! folic acid and derivative biosynthetic process GO:0009396 8 8 0,000 0,04448143 0,08665884 ! regulation of neuronal synaptic plasticity GO:0048168 8 8 0,000 0,04448143 0,08656734 ! cardiac muscle contraction GO:0060048 8 8 0,000 0,04448143 0,08647602 ! lipid localization GO:0010876 8 8 0,000 0,04448143 0,0863849 GO:0019915|lipid storage, ! response to pain GO:0048265 8 8 0,000 0,04448143 0,08629397 ! response to cAMP GO:0051591 8 8 0,000 0,04448143 0,08620322 ! COPI coating of Golgi vesicle GO:0048205 8 8 0,000 0,04448143 0,08611268 GO:0048200|Golgi transport vesicle coating, ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 8 0,000 0,04448143 0,08602232 ! negative regulation of transcription factor import into nucleus GO:0042992 8 8 0,000 0,04448143 0,08593215 ! negative regulation of ion transport GO:0043271 8 8 0,000 0,04448143 0,08584216 ! regulation of response to extracellular stimulus GO:0032104 8 8 0,000 0,04448143 0,08575237 GO:0032107|regulation of response to nutrient levels, ! adult walking behavior GO:0007628 8 8 0,000 0,04448143 0,08566277 ! sensory perception of taste GO:0050909 8 8 0,000 0,04448143 0,08557335 ! organelle fusion GO:0048284 8 8 0,000 0,04448143 0,08548412 ! pancreas development GO:0031016 8 8 0,000 0,04448143 0,08539507 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 8 8 0,000 0,04448143 0,08530621 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 8 8 0,000 0,04448143 0,08521753 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 8 8 0,000 0,04448143 0,08512904 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 8 8 0,000 0,04448143 0,08504073 ! sperm motility GO:0030317 8 8 0,000 0,04448143 0,08495261 ! regulation of striated muscle contraction GO:0006942 8 8 0,000 0,04448143 0,08486467 ! DNA duplex unwinding GO:0032508 8 8 0,000 0,04448143 0,0847769 GO:0032392|DNA geometric change, ! glycine metabolic process GO:0006544 8 8 0,000 0,04448143 0,08468933 ! ribonucleotide catabolic process GO:0009261 8 8 0,000 0,04448143 0,08460193 ! negative regulation of microtubule depolymerization GO:0007026 8 8 0,000 0,04448143 0,08451471 GO:0031114|regulation of microtubule depolymerization, ! phosphagen metabolic process GO:0006599 8 8 0,000 0,04448143 0,08442767 GO:0006600|creatine metabolic process, ! polyamine metabolic process GO:0006595 8 8 0,000 0,04448143 0,08434081 ! Golgi organization GO:0007030 8 8 0,000 0,04448143 0,08425413 ! cell-cell junction assembly GO:0007043 8 8 0,000 0,04448143 0,08416763 ! regulation of stress fiber formation GO:0051492 9 8 0,000 0,04448143 0,0840813 ! positive regulation of endothelial cell migration GO:0010595 8 8 0,000 0,04448143 0,08399515 ! fructose metabolic process GO:0006000 8 8 0,000 0,04448143 0,08390918 ! mannose metabolic process GO:0006013 9 8 0,000 0,04448143 0,08382338 ! NAD metabolic process GO:0019674 8 8 0,000 0,04448143 0,08373776 ! plasma membrane fusion GO:0045026 8 8 0,000 0,04448143 0,08365231 ! response to fungus GO:0009620 8 8 0,000 0,04448143 0,08356704 ! stem cell differentiation GO:0048863 8 8 0,000 0,04448143 0,08348194 ! embryonic digit morphogenesis GO:0042733 8 8 0,000 0,04448143 0,08339702 ! regulation of cytokine production during immune response GO:0002718 8 8 0,000 0,04448143 0,08331226 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 0,04448143 0,08322768 ! regulation of vasodilation GO:0042312 8 8 0,000 0,04448143 0,08314327 ! vasoconstriction GO:0042310 8 8 0,000 0,04448143 0,08305903 ! regulation of T cell mediated immunity GO:0002709 8 8 0,000 0,04448143 0,08297497 ! muscle cell development GO:0055001 8 8 0,000 0,04448143 0,08289107 ! nucleoside triphosphate catabolic process GO:0009143 8 8 0,000 0,04448143 0,08280734 ! regulation of fatty acid metabolic process GO:0019217 8 8 0,000 0,04448143 0,08272378 ! sensory perception of pain GO:0019233 8 8 0,000 0,04448143 0,08264039 ! gastrulation with mouth forming second GO:0001702 8 8 0,000 0,04448143 0,08255717 ! immunoglobulin production during immune response GO:0002381 8 8 0,000 0,04448143 0,08247411 GO:0002208|somatic diversification of immunoglobulins during immune response, GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! mRNA cleavage GO:0006379 8 8 0,000 0,04448143 0,08239122 ! chromatin silencing GO:0006342 8 8 0,000 0,04448143 0,0823085 ! tissue regeneration GO:0042246 8 8 0,000 0,04448143 0,08222594 ! salivary gland development GO:0007431 8 8 0,000 0,04448143 0,08214355 ! negative regulation of blood coagulation GO:0030195 9 8 0,000 0,04448143 0,08206133 ! peptide biosynthetic process GO:0043043 9 8 0,000 0,04448143 0,08197927 ! water homeostasis GO:0030104 8 8 0,000 0,04448143 0,08189737 ! cofactor transport GO:0051181 8 8 0,000 0,04448143 0,08181564 ! regulation of acute inflammatory response GO:0002673 8 8 0,000 0,04448143 0,08173406 ! acid secretion GO:0046717 8 8 0,000 0,04448143 0,08165266 ! positive regulation of leukocyte migration GO:0002687 8 8 0,000 0,04448143 0,08157141 ! C21-steroid hormone biosynthetic process GO:0006700 8 8 0,000 0,04448143 0,08149032 ! protein-chromophore linkage GO:0018298 9 8 0,000 0,04448143 0,0814094 ! regulation of immunoglobulin production GO:0002637 8 8 0,000 0,04448143 0,08132864 ! branched chain family amino acid metabolic process GO:0009081 8 8 0,000 0,04448143 0,08124803 ! catecholamine biosynthetic process GO:0042423 8 8 0,000 0,04448143 0,08116759 ! regulation of RNA stability GO:0043487 8 8 0,000 0,04448143 0,08108731 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 8 8 0,000 0,04448143 0,08100718 ! aromatic compound biosynthetic process GO:0019438 8 8 0,000 0,04448143 0,08092721 ! regulation of organic acid transport GO:0032890 8 8 0,000 0,04448143 0,0808474 ! positive regulation of calcium ion transport GO:0051928 8 8 0,000 0,04448143 0,08076775 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 8 8 0,000 0,04448143 0,08068825 ! regulation of multi-organism process GO:0043900 8 8 0,000 0,04448143 0,08060892 ! positive regulation of amine transport GO:0051954 8 8 0,000 0,04448143 0,08052973 ! developmental induction GO:0031128 8 8 0,000 0,04448143 0,0804507 GO:0045168|cell-cell signaling involved in cell fate specification, ! peptide hormone secretion GO:0030072 8 8 0,000 0,04448143 0,08037183 ! positive regulation of calcium-mediated signaling GO:0050850 8 8 0,000 0,04448143 0,08029311 ! actin filament polymerization GO:0030041 9 8 0,000 0,04448143 0,08021455 ! cytoplasmic sequestering of protein GO:0051220 8 8 0,000 0,04448143 0,08013614 ! peptide hormone processing GO:0016486 8 8 0,000 0,04448143 0,08005788 ! positive regulation of synaptic transmission GO:0050806 8 8 0,000 0,04448143 0,07997977 ! regulation of steroid biosynthetic process GO:0050810 8 8 0,000 0,04448143 0,07990182 ! protein polymerization GO:0051258 65 60 1,000 0,04509373 0,08092283 ! cellular respiration GO:0045333 62 61 1,000 0,04645859 0,08329102 ! regulation of protein amino acid phosphorylation GO:0001932 62 61 1,000 0,04645859 0,08321008 ! carboxylic acid catabolic process GO:0046395 63 61 1,000 0,04645859 0,08312929 GO:0016054|organic acid catabolic process, ! proteasomal protein catabolic process GO:0010498 62 61 1,000 0,04645859 0,08304866 GO:0043161|proteasomal ubiquitin-dependent protein catabolic process, ! morphogenesis of an epithelium GO:0002009 63 62 1,000 0,04783866 0,08543279 GO:0060429|epithelium development, ! protein import GO:0017038 62 62 1,000 0,04783866 0,08535009 ! regulation of lymphocyte activation GO:0051249 62 62 1,000 0,04783866 0,08526755 ! regulation of secretion GO:0051046 65 63 1,000 0,04923374 0,08766935 ! lactation GO:0007595 10 9 0,000 0,04990419 0,08877743 ! embryonic pattern specification GO:0009880 10 9 0,000 0,04990419 0,08869182 ! positive regulation of cell size GO:0045793 9 9 0,000 0,04990419 0,08860638 ! positive regulation of cell projection organization GO:0031346 9 9 0,000 0,04990419 0,0885211 ! regulation of membrane protein ectodomain proteolysis GO:0051043 9 9 0,000 0,04990419 0,08843598 ! positive regulation of protein complex assembly GO:0031334 9 9 0,000 0,04990419 0,08835103 ! cortical actin cytoskeleton organization GO:0030866 10 9 0,000 0,04990419 0,08826624 ! viral genome replication GO:0019079 9 9 0,000 0,04990419 0,08818161 ! phospholipid catabolic process GO:0009395 9 9 0,000 0,04990419 0,08809714 ! copper ion transport GO:0006825 9 9 0,000 0,04990419 0,08801284 ! lipid phosphorylation GO:0046834 9 9 0,000 0,04990419 0,0879287 ! aminoglycan catabolic process GO:0006026 9 9 0,000 0,04990419 0,08784472 ! Golgi vesicle budding GO:0048194 9 9 0,000 0,04990419 0,0877609 ! regulation of cell-cell adhesion GO:0022407 9 9 0,000 0,04990419 0,08767723 ! RNA polyadenylation GO:0043631 9 9 0,000 0,04990419 0,08759373 GO:0006378|mRNA polyadenylation, ! gamma-aminobutyric acid signaling pathway GO:0007214 9 9 0,000 0,04990419 0,08751039 ! regulation of postsynaptic membrane potential GO:0060078 9 9 0,000 0,04990419 0,0874272 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 9 9 0,000 0,04990419 0,08734418 ! negative regulation of cytokine biosynthetic process GO:0042036 9 9 0,000 0,04990419 0,08726131 ! phospholipid efflux GO:0033700 9 9 0,000 0,04990419 0,0871786 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 9 9 0,000 0,04990419 0,08709604 ! cytokine biosynthetic process GO:0042089 9 9 0,000 0,04990419 0,08701364 GO:0042107|cytokine metabolic process, ! positive regulation of endothelial cell proliferation GO:0001938 9 9 0,000 0,04990419 0,0869314 ! negative regulation of gene expression, epigenetic GO:0045814 9 9 0,000 0,04990419 0,08684931 ! regulation of interleukin-2 biosynthetic process GO:0045076 9 9 0,000 0,04990419 0,08676738 ! platelet-derived growth factor receptor signaling pathway GO:0048008 9 9 0,000 0,04990419 0,0866856 ! pyrimidine ribonucleotide metabolic process GO:0009218 9 9 0,000 0,04990419 0,08660397 ! methionine metabolic process GO:0006555 9 9 0,000 0,04990419 0,0865225 ! glutamine metabolic process GO:0006541 9 9 0,000 0,04990419 0,08644118 ! cerebral cortex development GO:0021987 9 9 0,000 0,04990419 0,08636002 ! response to osmotic stress GO:0006970 9 9 0,000 0,04990419 0,086279 ! pigmentation during development GO:0048066 9 9 0,000 0,04990419 0,08619814 ! reverse cholesterol transport GO:0043691 9 9 0,000 0,04990419 0,08611743 ! central nervous system neuron development GO:0021954 10 9 0,000 0,04990419 0,08603687 ! pyrimidine ribonucleoside metabolic process GO:0046131 9 9 0,000 0,04990419 0,08595647 ! nucleobase biosynthetic process GO:0046112 9 9 0,000 0,04990419 0,08587621 ! substrate-bound cell migration GO:0006929 9 9 0,000 0,04990419 0,0857961 ! neurotransmitter metabolic process GO:0042133 11 9 0,000 0,04990419 0,08571614 ! negative regulation of caspase activity GO:0043154 9 9 0,000 0,04990419 0,08563633 ! L-glutamate transport GO:0015813 9 9 0,000 0,04990419 0,08555667 GO:0015800|acidic amino acid transport, ! peptide secretion GO:0002790 9 9 0,000 0,04990419 0,08547715 ! regulation of dephosphorylation GO:0035303 9 9 0,000 0,04990419 0,08539779 ! cotranslational protein targeting to membrane GO:0006613 10 9 0,000 0,04990419 0,08531857 ! positive regulation of alpha-beta T cell differentiation GO:0046638 9 9 0,000 0,04990419 0,0852395 ! ventricular cardiac muscle morphogenesis GO:0055010 9 9 0,000 0,04990419 0,08516057 ! behavioral interaction between organisms GO:0051705 9 9 0,000 0,04990419 0,08508179 ! negative regulation of protein import into nucleus GO:0042308 9 9 0,000 0,04990419 0,08500316 ! positive regulation of protein import into nucleus GO:0042307 9 9 0,000 0,04990419 0,08492467 ! DNA replication initiation GO:0006270 9 9 0,000 0,04990419 0,08484633 ! DNA fragmentation involved in apoptosis GO:0006309 9 9 0,000 0,04990419 0,08476813 ! regulation of immunoglobulin mediated immune response GO:0002889 9 9 0,000 0,04990419 0,08469007 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 10 9 0,000 0,04990419 0,08461216 ! positive regulation of oxidoreductase activity GO:0051353 9 9 0,000 0,04990419 0,08453439 ! positive regulation of cytokine secretion GO:0050715 9 9 0,000 0,04990419 0,08445677 ! negative regulation of inflammatory response GO:0050728 9 9 0,000 0,04990419 0,08437928 ! negative regulation of protein secretion GO:0050709 9 9 0,000 0,04990419 0,08430194 ! regulation of leukocyte migration GO:0002685 9 9 0,000 0,04990419 0,08422474 ! positive regulation of transmission of nerve impulse GO:0051971 9 9 0,000 0,04990419 0,08414768 ! collagen catabolic process GO:0030574 9 9 0,000 0,04990419 0,08407077 ! aromatic amino acid family catabolic process GO:0009074 9 9 0,000 0,04990419 0,08399399 ! purine base metabolic process GO:0006144 9 9 0,000 0,04990419 0,08391735 ! gas transport GO:0015669 9 9 0,000 0,04990419 0,08384086 ! cholesterol efflux GO:0033344 9 9 0,000 0,04990419 0,0837645 ! regulation of leukocyte mediated cytotoxicity GO:0001910 9 9 0,000 0,04990419 0,08368828 ! estrogen receptor signaling pathway GO:0030520 9 9 0,000 0,04990419 0,0836122 ! somatic recombination of immunoglobulin gene segments GO:0016447 9 9 0,000 0,04990419 0,08353626 ! regulation of actin filament bundle formation GO:0032231 10 9 0,000 0,04990419 0,08346045 ! regulation of blood vessel endothelial cell migration GO:0043535 9 9 0,000 0,04990419 0,08338479 ! regulation of calcium-mediated signaling GO:0050848 9 9 0,000 0,04990419 0,08330926 ! actin filament-based movement GO:0030048 9 9 0,000 0,04990419 0,08323386 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 9 9 0,000 0,04990419 0,08315861 ! glycerolipid metabolic process GO:0046486 65 64 1,000 0,05064363 0,08431455 ! regulation of cytoskeleton organization GO:0051493 66 64 1,000 0,05064363 0,08423846 ! regulation of hormone levels GO:0010817 66 65 1,000 0,05206812 0,0865298 ! polysaccharide metabolic process GO:0005976 69 66 1,000 0,05350702 0,08884094 ! negative regulation of cell differentiation GO:0045596 68 67 1,000 0,05496012 0,09117147 ! protein import into nucleus, docking GO:0000059 10 10 0,000 0,05529696 0,09164775 ! regulation of protein ubiquitination GO:0031396 10 10 0,000 0,05529696 0,09156541 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 10 10 0,000 0,05529696 0,09148321 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 10 10 0,000 0,05529696 0,09140116 ! ER-associated protein catabolic process GO:0030433 10 10 0,000 0,05529696 0,09131926 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of cell killing GO:0031341 10 10 0,000 0,05529696 0,09123751 ! neuron maturation GO:0042551 10 10 0,000 0,05529696 0,0911559 ! pteridine and derivative metabolic process GO:0042558 10 10 0,000 0,05529696 0,09107444 ! positive regulation of anti-apoptosis GO:0045768 10 10 0,000 0,05529696 0,09099312 GO:0045767|regulation of anti-apoptosis, ! cortical cytoskeleton organization GO:0030865 11 10 0,000 0,05529696 0,09091195 ! regulation of lipid biosynthetic process GO:0046890 10 10 0,000 0,05529696 0,09083092 ! reciprocal meiotic recombination GO:0007131 10 10 0,000 0,05529696 0,09075004 ! hormone secretion GO:0046879 10 10 0,000 0,05529696 0,0906693 ! glucosamine metabolic process GO:0006041 10 10 0,000 0,05529696 0,09058871 GO:0006044|N-acetylglucosamine metabolic process, ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 10 10 0,000 0,05529696 0,09050826 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! negative regulation of nucleocytoplasmic transport GO:0046823 10 10 0,000 0,05529696 0,09042795 ! inositol metabolic process GO:0006020 10 10 0,000 0,05529696 0,09034778 ! cAMP metabolic process GO:0046058 10 10 0,000 0,05529696 0,09026776 ! vesicle targeting, to, from or within Golgi GO:0048199 10 10 0,000 0,05529696 0,09018787 ! transcription from RNA polymerase III promoter GO:0006383 10 10 0,000 0,05529696 0,09010813 ! forelimb morphogenesis GO:0035136 10 10 0,000 0,05529696 0,09002853 ! glial cell development GO:0021782 10 10 0,000 0,05529696 0,08994907 ! phototransduction GO:0007602 11 10 0,000 0,05529696 0,08986975 ! calcium-independent cell-cell adhesion GO:0016338 10 10 0,000 0,05529696 0,08979057 ! auditory receptor cell differentiation GO:0042491 10 10 0,000 0,05529696 0,08971153 ! fat cell differentiation GO:0045444 10 10 0,000 0,05529696 0,08963263 ! myoblast differentiation GO:0045445 10 10 0,000 0,05529696 0,08955386 ! centrosome cycle GO:0007098 10 10 0,000 0,05529696 0,08947524 ! inactivation of MAPK activity GO:0000188 10 10 0,000 0,05529696 0,08939675 ! positive regulation of proteolysis GO:0045862 10 10 0,000 0,05529696 0,0893184 ! response to carbohydrate stimulus GO:0009743 10 10 0,000 0,05529696 0,08924019 ! regulation of survival gene product expression GO:0045884 10 10 0,000 0,05529696 0,08916211 ! induction of apoptosis via death domain receptors GO:0008625 10 10 0,000 0,05529696 0,08908418 ! protein polyubiquitination GO:0000209 10 10 0,000 0,05529696 0,08900637 ! glutamate metabolic process GO:0006536 11 10 0,000 0,05529696 0,08892871 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 10 10 0,000 0,05529696 0,08885117 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! lysosomal transport GO:0007041 10 10 0,000 0,05529696 0,08877378 ! cellular response to unfolded protein GO:0034620 10 10 0,000 0,05529696 0,08869652 GO:0030968|endoplasmic reticulum unfolded protein response, ! central nervous system neuron differentiation GO:0021953 11 10 0,000 0,05529696 0,08861939 ! purine ribonucleoside metabolic process GO:0046128 10 10 0,000 0,05529696 0,0885424 GO:0042278|purine nucleoside metabolic process, ! vesicle coating GO:0006901 10 10 0,000 0,05529696 0,08846554 ! exocrine system development GO:0035272 10 10 0,000 0,05529696 0,08838881 ! cell structure disassembly during apoptosis GO:0006921 10 10 0,000 0,05529696 0,08831222 ! embryo implantation GO:0007566 11 10 0,000 0,05529696 0,08823576 ! protein targeting to peroxisome GO:0006625 10 10 0,000 0,05529696 0,08815943 ! protein targeting to mitochondrion GO:0006626 10 10 0,000 0,05529696 0,08808323 GO:0070585|protein localization in mitochondrion, ! regulation of alpha-beta T cell differentiation GO:0046637 10 10 0,000 0,05529696 0,08800716 ! intermediate filament cytoskeleton organization GO:0045104 10 10 0,000 0,05529696 0,08793123 ! protein export from nucleus GO:0006611 10 10 0,000 0,05529696 0,08785543 ! negative regulation of immune response GO:0050777 10 10 0,000 0,05529696 0,08777976 ! cytolysis GO:0019835 10 10 0,000 0,05529696 0,08770421 ! positive regulation of biomineral formation GO:0070169 10 10 0,000 0,05529696 0,0876288 GO:0030501|positive regulation of bone mineralization, ! mismatch repair GO:0006298 10 10 0,000 0,05529696 0,08755352 ! regulation of B cell differentiation GO:0045577 10 10 0,000 0,05529696 0,08747837 ! mRNA splice site selection GO:0006376 11 10 0,000 0,05529696 0,08740334 ! synaptic vesicle transport GO:0048489 11 10 0,000 0,05529696 0,08732845 ! positive regulation of neurological system process GO:0031646 10 10 0,000 0,05529696 0,08725368 ! sphingolipid biosynthetic process GO:0030148 10 10 0,000 0,05529696 0,08717904 GO:0046467|membrane lipid biosynthetic process, ! sphingolipid catabolic process GO:0030149 10 10 0,000 0,05529696 0,08710453 GO:0046466|membrane lipid catabolic process, ! nerve-nerve synaptic transmission GO:0007270 10 10 0,000 0,05529696 0,08703014 ! regulation of erythrocyte differentiation GO:0045646 10 10 0,000 0,05529696 0,08695588 ! regulation of epidermis development GO:0045682 10 10 0,000 0,05529696 0,08688175 ! folic acid and derivative metabolic process GO:0006760 10 10 0,000 0,05529696 0,08680775 ! negative regulation of neuron differentiation GO:0045665 10 10 0,000 0,05529696 0,08673387 ! aspartate family amino acid biosynthetic process GO:0009067 10 10 0,000 0,05529696 0,08666012 ! regulation of BMP signaling pathway GO:0030510 10 10 0,000 0,05529696 0,08658649 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 10 10 0,000 0,05529696 0,08651299 ! nerve development GO:0021675 10 10 0,000 0,05529696 0,08643961 ! epithelial to mesenchymal transition GO:0001837 10 10 0,000 0,05529696 0,08636635 ! embryonic organ morphogenesis GO:0048562 10 10 0,000 0,05529696 0,08629322 ! mRNA 3'-end processing GO:0031124 10 10 0,000 0,05529696 0,08622022 ! antigen receptor-mediated signaling pathway GO:0050851 10 10 0,000 0,05529696 0,08614733 ! negative regulation of coagulation GO:0050819 11 10 0,000 0,05529696 0,08607458 ! protein stabilization GO:0050821 10 10 0,000 0,05529696 0,08600194 ! sensory perception of sound GO:0007605 71 69 1,000 0,05790814 0,08998711 GO:0050954|sensory perception of mechanical stimulus, ! regionalization GO:0003002 70 69 1,000 0,05790814 0,0899113 ! regulation of leukocyte activation GO:0002694 69 69 1,000 0,05790814 0,08983562 ! carboxylic acid biosynthetic process GO:0046394 70 70 1,000 0,05940268 0,09207665 GO:0016053|organic acid biosynthetic process, ! protein secretion GO:0009306 11 11 0,000 0,0606599 0,09394639 ! oligosaccharide metabolic process GO:0009311 11 11 0,000 0,0606599 0,09386751 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 11 11 0,000 0,0606599 0,09378876 ! myeloid leukocyte differentiation GO:0002573 12 11 0,000 0,0606599 0,09371014 ! negative regulation of defense response GO:0031348 11 11 0,000 0,0606599 0,09363166 ! G1 phase of mitotic cell cycle GO:0000080 12 11 0,000 0,0606599 0,09355331 ! determination of bilateral symmetry GO:0009855 11 11 0,000 0,0606599 0,09347508 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! phosphatidylinositol metabolic process GO:0046488 11 11 0,000 0,0606599 0,09339699 ! skin development GO:0043588 11 11 0,000 0,0606599 0,09331903 ! cellular component assembly involved in morphogenesis GO:0010927 11 11 0,000 0,0606599 0,0932412 ! signal complex assembly GO:0007172 11 11 0,000 0,0606599 0,0931635 ! microtubule-based transport GO:0010970 11 11 0,000 0,0606599 0,09308593 ! endothelial cell migration GO:0043542 11 11 0,000 0,0606599 0,09300849 ! peroxisomal transport GO:0043574 11 11 0,000 0,0606599 0,09293117 ! protein amino acid methylation GO:0006479 11 11 0,000 0,0606599 0,09285399 GO:0008213|protein amino acid alkylation, ! heart contraction GO:0060047 11 11 0,000 0,0606599 0,09277693 GO:0003015|heart process, ! detection of light stimulus involved in sensory perception GO:0050962 12 11 0,000 0,0606599 0,0927 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 11 11 0,000 0,0606599 0,0926232 ! T cell proliferation GO:0042098 11 11 0,000 0,0606599 0,09254652 ! regulation of transmembrane transporter activity GO:0022898 11 11 0,000 0,0606599 0,09246998 GO:0032412|regulation of ion transmembrane transporter activity, GO:0032409|regulation of transporter activity, ! negative regulation of endothelial cell proliferation GO:0001937 11 11 0,000 0,0606599 0,09239355 ! spinal cord development GO:0021510 11 11 0,000 0,0606599 0,09231726 ! activation of MAPKK activity GO:0000186 12 11 0,000 0,0606599 0,09224109 ! smooth muscle contraction GO:0006939 11 11 0,000 0,0606599 0,09216505 ! cellular macromolecular complex disassembly GO:0034623 12 11 0,000 0,0606599 0,09208913 ! digestive system process GO:0022600 11 11 0,000 0,0606599 0,09201333 ! mitotic spindle organization GO:0007052 11 11 0,000 0,0606599 0,09193767 ! fucose metabolic process GO:0006004 11 11 0,000 0,0606599 0,09186212 ! membrane budding GO:0006900 11 11 0,000 0,0606599 0,0917867 ! apoptotic nuclear changes GO:0030262 11 11 0,000 0,0606599 0,0917114 ! monoamine transport GO:0015844 11 11 0,000 0,0606599 0,09163623 ! regulation of cellular ketone metabolic process GO:0010565 11 11 0,000 0,0606599 0,09156118 ! response to lipopolysaccharide GO:0032496 11 11 0,000 0,0606599 0,09148625 ! body fluid secretion GO:0007589 11 11 0,000 0,0606599 0,09141145 ! positive regulation of alpha-beta T cell activation GO:0046635 11 11 0,000 0,0606599 0,09133677 ! intermediate filament-based process GO:0045103 11 11 0,000 0,0606599 0,0912622 ! cardiac muscle tissue morphogenesis GO:0055008 11 11 0,000 0,0606599 0,09118777 GO:0060415|muscle tissue morphogenesis, ! membrane depolarization GO:0051899 11 11 0,000 0,0606599 0,09111345 ! regulation of interleukin-2 production GO:0032663 11 11 0,000 0,0606599 0,09103925 ! regulation of ARF GTPase activity GO:0032312 11 11 0,000 0,0606599 0,09096518 ! negative regulation of angiogenesis GO:0016525 11 11 0,000 0,0606599 0,09089122 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 11 11 0,000 0,0606599 0,09081739 ! vitamin transport GO:0051180 11 11 0,000 0,0606599 0,09074367 ! muscle maintenance GO:0046716 12 11 0,000 0,0606599 0,09067007 ! vitamin A metabolic process GO:0006776 11 11 0,000 0,0606599 0,0905966 ! steroid catabolic process GO:0006706 11 11 0,000 0,0606599 0,09052324 ! endocrine process GO:0050886 11 11 0,000 0,0606599 0,09045 GO:0001990|regulation of systemic arterial blood pressure by hormone, ! aromatic amino acid family metabolic process GO:0009072 11 11 0,000 0,0606599 0,09037688 ! proximal/distal pattern formation GO:0009954 11 11 0,000 0,0606599 0,09030388 ! somatic diversification of immunoglobulins GO:0016445 11 11 0,000 0,0606599 0,09023099 ! RNA 3'-end processing GO:0031123 11 11 0,000 0,0606599 0,09015823 ! calcium ion homeostasis GO:0055074 71 71 1,000 0,06091063 0,09045793 GO:0006874|cellular calcium ion homeostasis, ! regulation of cell activation GO:0050865 71 71 1,000 0,06091063 0,0903851 ! sensory organ development GO:0007423 72 72 1,000 0,06243181 0,09256785 ! coenzyme metabolic process GO:0006732 75 74 1,000 0,06551312 0,09705842 ! positive regulation of protein catabolic process GO:0045732 12 12 0,000 0,06599318 0,09769111 ! translational initiation GO:0006413 12 12 0,000 0,06599318 0,0976127 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 12 12 0,000 0,06599318 0,09753442 ! positive regulation of angiogenesis GO:0045766 12 12 0,000 0,06599318 0,09745627 ! initiation of viral infection GO:0019059 12 12 0,000 0,06599318 0,09737824 ! DNA catabolic process, endonucleolytic GO:0000737 12 12 0,000 0,06599318 0,09730034 ! iron ion transport GO:0006826 13 12 0,000 0,06599318 0,09722256 ! phosphatidylcholine metabolic process GO:0046470 12 12 0,000 0,06599318 0,09714491 ! amino sugar metabolic process GO:0006040 12 12 0,000 0,06599318 0,09706738 ! post-Golgi vesicle-mediated transport GO:0006892 12 12 0,000 0,06599318 0,09698997 ! protein amino acid ADP-ribosylation GO:0006471 12 12 0,000 0,06599318 0,09691269 ! heterophilic cell adhesion GO:0007157 12 12 0,000 0,06599318 0,09683553 ! collagen metabolic process GO:0032963 12 12 0,000 0,06599318 0,09675849 ! hindlimb morphogenesis GO:0035137 12 12 0,000 0,06599318 0,09668158 ! xenobiotic metabolic process GO:0006805 12 12 0,000 0,06599318 0,09660479 ! glutamate signaling pathway GO:0007215 12 12 0,000 0,06599318 0,09652812 ! C21-steroid hormone metabolic process GO:0008207 13 12 0,000 0,06599318 0,09645157 ! regulation of muscle cell differentiation GO:0051147 13 12 0,000 0,06599318 0,09637514 ! cellular response to hydrogen peroxide GO:0070301 12 12 0,000 0,06599318 0,09629883 GO:0042744|hydrogen peroxide catabolic process, ! negative regulation of peptidase activity GO:0010466 12 12 0,000 0,06599318 0,09622265 ! actomyosin structure organization GO:0031032 12 12 0,000 0,06599318 0,09614658 ! microtubule organizing center organization GO:0031023 12 12 0,000 0,06599318 0,09607064 GO:0051297|centrosome organization, ! positive regulation of endocytosis GO:0045807 12 12 0,000 0,06599318 0,09599481 ! retinoid metabolic process GO:0001523 12 12 0,000 0,06599318 0,09591911 GO:0016101|diterpenoid metabolic process, ! mitotic chromosome condensation GO:0007076 12 12 0,000 0,06599318 0,09584352 ! positive regulation of innate immune response GO:0045089 12 12 0,000 0,06599318 0,09576805 ! GPI anchor biosynthetic process GO:0006506 12 12 0,000 0,06599318 0,0956927 GO:0006505|GPI anchor metabolic process, ! glycoprotein catabolic process GO:0006516 13 12 0,000 0,06599318 0,09561747 ! acute-phase response GO:0006953 12 12 0,000 0,06599318 0,09554236 ! deoxyribonucleotide catabolic process GO:0009264 12 12 0,000 0,06599318 0,09546737 ! vacuolar transport GO:0007034 12 12 0,000 0,06599318 0,09539249 ! polysaccharide catabolic process GO:0000272 12 12 0,000 0,06599318 0,09531773 ! vesicle docking during exocytosis GO:0006904 12 12 0,000 0,06599318 0,09524309 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 12 12 0,000 0,06599318 0,09516857 ! barbed-end actin filament capping GO:0051016 12 12 0,000 0,06599318 0,09509416 GO:0051693|actin filament capping, ! osteoblast differentiation GO:0001649 12 12 0,000 0,06599318 0,09501986 ! regulation of alpha-beta T cell activation GO:0046634 12 12 0,000 0,06599318 0,09494569 ! regulation of tumor necrosis factor production GO:0032680 12 12 0,000 0,06599318 0,09487163 ! regulation of steroid metabolic process GO:0019218 12 12 0,000 0,06599318 0,09479768 ! fibroblast growth factor receptor signaling pathway GO:0008543 12 12 0,000 0,06599318 0,09472385 ! regulation of interleukin-6 production GO:0032675 12 12 0,000 0,06599318 0,09465014 ! pallium development GO:0021543 13 12 0,000 0,06599318 0,09457654 ! cell fate determination GO:0001709 12 12 0,000 0,06599318 0,09450305 ! regulation of response to biotic stimulus GO:0002831 12 12 0,000 0,06599318 0,09442968 ! positive regulation of adaptive immune response GO:0002821 12 12 0,000 0,06599318 0,09435642 ! detection of light stimulus GO:0009583 13 12 0,000 0,06599318 0,09428328 ! synaptogenesis GO:0007416 12 12 0,000 0,06599318 0,09421024 ! fat-soluble vitamin metabolic process GO:0006775 12 12 0,000 0,06599318 0,09413733 ! hormone transport GO:0009914 12 12 0,000 0,06599318 0,09406452 ! neurotransmitter secretion GO:0007269 14 12 0,000 0,06599318 0,09399183 ! heme biosynthetic process GO:0006783 12 12 0,000 0,06599318 0,09391925 ! spermatid differentiation GO:0048515 13 12 0,000 0,06599318 0,09384678 GO:0007286|spermatid development, ! aromatic compound catabolic process GO:0019439 13 12 0,000 0,06599318 0,09377442 ! pyrimidine nucleotide biosynthetic process GO:0006221 12 12 0,000 0,06599318 0,09370218 ! neural tube closure GO:0001843 13 12 0,000 0,06599318 0,09363004 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! negative regulation of translation GO:0017148 12 12 0,000 0,06599318 0,09355802 ! regulation of microtubule polymerization or depolymerization GO:0031110 12 12 0,000 0,06599318 0,09348611 ! positive regulation of multicellular organismal process GO:0051240 76 76 1,000 0,06864509 0,09716813 ! cellular metal ion homeostasis GO:0006875 77 77 1,000 0,07022962 0,09933476 ! positive regulation of smooth muscle cell proliferation GO:0048661 13 13 0,000 0,07129694 0,10076708 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 13 13 0,000 0,07129694 0,10068986 GO:0016444|somatic cell DNA recombination, ! negative regulation of actin filament polymerization GO:0030837 13 13 0,000 0,07129694 0,10061276 ! phenol metabolic process GO:0018958 13 13 0,000 0,07129694 0,10053578 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, GO:0009712|catechol metabolic process, ! G2/M transition of mitotic cell cycle GO:0000086 13 13 0,000 0,07129694 0,10045892 ! 2'-deoxyribonucleotide metabolic process GO:0009394 13 13 0,000 0,07129694 0,10038218 GO:0019692|deoxyribose phosphate metabolic process, ! intra-Golgi vesicle-mediated transport GO:0006891 13 13 0,000 0,07129694 0,10030555 ! glycosaminoglycan biosynthetic process GO:0006024 13 13 0,000 0,07129694 0,10022904 ! positive regulation of JAK-STAT cascade GO:0046427 13 13 0,000 0,07129694 0,10015264 ! keratinization GO:0031424 13 13 0,000 0,07129694 0,10007637 ! negative regulation of protein modification process GO:0031400 13 13 0,000 0,07129694 0,1000002 ! patterning of blood vessels GO:0001569 13 13 0,000 0,07129694 0,09992416 ! vasculogenesis GO:0001570 13 13 0,000 0,07129694 0,09984823 ! regulation of DNA recombination GO:0000018 13 13 0,000 0,07129694 0,09977241 ! regulation of innate immune response GO:0045088 13 13 0,000 0,07129694 0,09969671 ! multicellular organismal macromolecule metabolic process GO:0044259 13 13 0,000 0,07129694 0,09962113 ! multicellular organismal catabolic process GO:0044243 13 13 0,000 0,07129694 0,09954566 ! autophagy GO:0006914 13 13 0,000 0,07129694 0,0994703 ! receptor metabolic process GO:0043112 14 13 0,000 0,07129694 0,09939506 ! actin filament bundle formation GO:0051017 13 13 0,000 0,07129694 0,09931993 ! negative regulation of protein catabolic process GO:0042177 13 13 0,000 0,07129694 0,09924491 ! regulation of endothelial cell migration GO:0010594 13 13 0,000 0,07129694 0,09917001 ! negative regulation of protein kinase cascade GO:0010741 13 13 0,000 0,07129694 0,09909522 ! purine nucleoside monophosphate metabolic process GO:0009126 13 13 0,000 0,07129694 0,09902055 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! nucleobase metabolic process GO:0009112 13 13 0,000 0,07129694 0,09894598 ! regulation of axonogenesis GO:0050770 14 13 0,000 0,07129694 0,09887153 ! positive regulation of neurogenesis GO:0050769 13 13 0,000 0,07129694 0,09879719 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 14 13 0,000 0,07129694 0,09872297 ! nucleotide-excision repair, DNA gap filling GO:0006297 13 13 0,000 0,07129694 0,09864885 ! vasodilation GO:0042311 14 13 0,000 0,07129694 0,09857484 ! positive regulation of leukocyte mediated immunity GO:0002705 13 13 0,000 0,07129694 0,09850095 GO:0002708|positive regulation of lymphocyte mediated immunity, ! glycosphingolipid metabolic process GO:0006687 13 13 0,000 0,07129694 0,09842717 GO:0006664|glycolipid metabolic process, ! positive regulation of locomotion GO:0040017 13 13 0,000 0,07129694 0,09835349 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, GO:0050920|regulation of chemotaxis, ! neural crest cell migration GO:0001755 14 13 0,000 0,07129694 0,09827993 ! neutrophil chemotaxis GO:0030593 14 13 0,000 0,07129694 0,09820648 ! long-chain fatty acid transport GO:0015909 13 13 0,000 0,07129694 0,09813313 ! immunoglobulin production GO:0002377 13 13 0,000 0,07129694 0,0980599 GO:0002440|production of molecular mediator of immune response, ! negative regulation of Wnt receptor signaling pathway GO:0030178 13 13 0,000 0,07129694 0,09798678 ! negative regulation of intracellular transport GO:0032387 13 13 0,000 0,07129694 0,09791376 ! cell-cell junction organization GO:0045216 13 13 0,000 0,07129694 0,09784085 ! negative regulation of myeloid cell differentiation GO:0045638 13 13 0,000 0,07129694 0,09776806 ! activation of JUN kinase activity GO:0007257 13 13 0,000 0,07129694 0,09769537 ! terpenoid metabolic process GO:0006721 13 13 0,000 0,07129694 0,09762278 ! alkene biosynthetic process GO:0043450 13 13 0,000 0,07129694 0,09755031 GO:0019370|leukotriene biosynthetic process, ! purine nucleotide catabolic process GO:0006195 13 13 0,000 0,07129694 0,09747794 ! porphyrin biosynthetic process GO:0006779 13 13 0,000 0,07129694 0,09740568 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of cytokine production GO:0001818 13 13 0,000 0,07129694 0,09733353 ! camera-type eye morphogenesis GO:0048593 13 13 0,000 0,07129694 0,09726149 ! pyrimidine nucleoside metabolic process GO:0006213 13 13 0,000 0,07129694 0,09718955 ! blastocyst development GO:0001824 13 13 0,000 0,07129694 0,09711771 ! water-soluble vitamin biosynthetic process GO:0042364 13 13 0,000 0,07129694 0,09704599 ! regulation of amine transport GO:0051952 13 13 0,000 0,07129694 0,09697437 ! inner ear receptor cell differentiation GO:0060113 13 13 0,000 0,07129694 0,09690285 ! regulation of protein modification process GO:0031399 79 78 1,000 0,07182627 0,09755034 ! microtubule-based movement GO:0007018 82 78 1,000 0,07182627 0,0974785 ! positive regulation of protein kinase cascade GO:0010740 79 78 1,000 0,07182627 0,09740677 ! metal ion homeostasis GO:0055065 78 78 1,000 0,07182627 0,09733515 ! nuclear transport GO:0051169 79 79 1,000 0,07343485 0,0994419 GO:0006913|nucleocytoplasmic transport, ! neuron fate commitment GO:0048663 14 14 0,000 0,07657136 0,10361308 ! sulfur amino acid metabolic process GO:0000096 14 14 0,000 0,07657136 0,10353706 ! regulation of interferon-gamma production GO:0032649 14 14 0,000 0,07657136 0,10346116 ! cellular aldehyde metabolic process GO:0006081 14 14 0,000 0,07657136 0,10338536 ! cellular iron ion homeostasis GO:0006879 14 14 0,000 0,07657136 0,10330968 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 14 14 0,000 0,07657136 0,1032341 ! regulation of neuron projection development GO:0010975 15 14 0,000 0,07657136 0,10315864 ! aminoglycan biosynthetic process GO:0006023 14 14 0,000 0,07657136 0,10308329 ! vesicle docking GO:0048278 14 14 0,000 0,07657136 0,10300804 ! superoxide metabolic process GO:0006801 15 14 0,000 0,07657136 0,10293291 ! macromolecular complex disassembly GO:0032984 15 14 0,000 0,07657136 0,10285788 ! calcium-dependent cell-cell adhesion GO:0016339 14 14 0,000 0,07657136 0,10278297 ! mechanoreceptor differentiation GO:0042490 14 14 0,000 0,07657136 0,10270816 ! isoprenoid biosynthetic process GO:0008299 14 14 0,000 0,07657136 0,10263347 ! negative regulation of epithelial cell proliferation GO:0050680 14 14 0,000 0,07657136 0,10255888 ! immune response-activating cell surface receptor signaling pathway GO:0002429 14 14 0,000 0,07657136 0,1024844 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! response to retinoic acid GO:0032526 14 14 0,000 0,07657136 0,10241003 GO:0033189|response to vitamin A, ! lysosome organization GO:0007040 14 14 0,000 0,07657136 0,10233576 ! actin polymerization or depolymerization GO:0008154 15 14 0,000 0,07657136 0,10226161 ! D-ribose metabolic process GO:0006014 14 14 0,000 0,07657136 0,10218756 ! peptide transport GO:0015833 14 14 0,000 0,07657136 0,10211362 ! primary neural tube formation GO:0014020 15 14 0,000 0,07657136 0,10203978 ! peptide cross-linking GO:0018149 14 14 0,000 0,07657136 0,10196605 ! regulation of behavior GO:0050795 14 14 0,000 0,07657136 0,10189243 ! vitamin biosynthetic process GO:0009110 14 14 0,000 0,07657136 0,10181892 ! leukotriene metabolic process GO:0006691 14 14 0,000 0,07657136 0,10174551 ! regulation of vasoconstriction GO:0019229 14 14 0,000 0,07657136 0,1016722 ! formation of primary germ layer GO:0001704 14 14 0,000 0,07657136 0,101599 GO:0001707|mesoderm formation, ! collagen fibril organization GO:0030199 14 14 0,000 0,07657136 0,10152591 ! proteoglycan biosynthetic process GO:0030166 14 14 0,000 0,07657136 0,10145292 ! regulation of blood coagulation GO:0030193 15 14 0,000 0,07657136 0,10138004 ! positive regulation of inflammatory response GO:0050729 14 14 0,000 0,07657136 0,10130726 ! group transfer coenzyme metabolic process GO:0006752 14 14 0,000 0,07657136 0,10123459 ! positive regulation of osteoblast differentiation GO:0045669 14 14 0,000 0,07657136 0,10116202 ! neuromuscular process controlling balance GO:0050885 14 14 0,000 0,07657136 0,10108955 ! aspartate family amino acid metabolic process GO:0009066 14 14 0,000 0,07657136 0,10101719 ! response to molecule of bacterial origin GO:0002237 14 14 0,000 0,07657136 0,10094493 ! negative regulation of protein polymerization GO:0032272 14 14 0,000 0,07657136 0,10087278 ! lipid catabolic process GO:0016042 82 81 1,000 0,07668712 0,10095311 ! positive regulation of fibroblast proliferation GO:0048146 15 15 0,000 0,08181659 0,10762881 ! negative regulation of actin filament depolymerization GO:0030835 15 15 0,000 0,08181659 0,10755205 ! positive regulation of ossification GO:0045778 15 15 0,000 0,08181659 0,10747539 GO:0046852|positive regulation of bone remodeling, GO:0034105|positive regulation of tissue remodeling, ! negative regulation of protein complex assembly GO:0031333 15 15 0,000 0,08181659 0,10739884 ! protein amino acid O-linked glycosylation GO:0006493 15 15 0,000 0,08181659 0,1073224 ! cellular polysaccharide biosynthetic process GO:0033692 15 15 0,000 0,08181659 0,10724607 ! proteoglycan metabolic process GO:0006029 15 15 0,000 0,08181659 0,10716984 ! response to vitamin GO:0033273 15 15 0,000 0,08181659 0,10709373 ! regulation of transcription factor import into nucleus GO:0042990 15 15 0,000 0,08181659 0,10701772 ! odontogenesis of dentine-containing tooth GO:0042475 15 15 0,000 0,08181659 0,10694182 ! detection of stimulus involved in sensory perception GO:0050906 16 15 0,000 0,08181659 0,10686603 ! antigen processing and presentation of peptide antigen GO:0048002 15 15 0,000 0,08181659 0,10679035 ! regulation of smooth muscle contraction GO:0006940 15 15 0,000 0,08181659 0,10671477 ! deoxyribonucleotide metabolic process GO:0009262 15 15 0,000 0,08181659 0,1066393 ! complement activation, classical pathway GO:0006958 15 15 0,000 0,08181659 0,10656393 ! heme metabolic process GO:0042168 15 15 0,000 0,08181659 0,10648868 ! mesoderm morphogenesis GO:0048332 15 15 0,000 0,08181659 0,10641353 ! chromosome condensation GO:0030261 15 15 0,000 0,08181659 0,10633848 ! response to mechanical stimulus GO:0009612 15 15 0,000 0,08181659 0,10626354 ! hydrogen peroxide metabolic process GO:0042743 15 15 0,000 0,08181659 0,10618871 ! regulation of biomineral formation GO:0070167 15 15 0,000 0,08181659 0,10611398 GO:0030500|regulation of bone mineralization, ! regulation of production of molecular mediator of immune response GO:0002700 15 15 0,000 0,08181659 0,10603936 ! cyclic nucleotide biosynthetic process GO:0009190 15 15 0,000 0,08181659 0,10596484 ! cholesterol biosynthetic process GO:0006695 15 15 0,000 0,08181659 0,10589043 ! phospholipid transport GO:0015914 15 15 0,000 0,08181659 0,10581612 ! regulation of cytokine secretion GO:0050707 15 15 0,000 0,08181659 0,10574191 ! glutathione metabolic process GO:0006749 16 15 0,000 0,08181659 0,10566781 ! nicotinamide metabolic process GO:0006769 15 15 0,000 0,08181659 0,10559381 GO:0046496|nicotinamide nucleotide metabolic process, ! positive regulation of B cell activation GO:0050871 15 15 0,000 0,08181659 0,10551992 ! cellular alkene metabolic process GO:0043449 15 15 0,000 0,08181659 0,10544613 ! negative regulation of transcription factor activity GO:0043433 16 15 0,000 0,08181659 0,10537244 GO:0090048|negative regulation of transcription regulator activity, ! somatic diversification of immune receptors GO:0002200 15 15 0,000 0,08181659 0,10529886 ! protein homooligomerization GO:0051260 15 15 0,000 0,08181659 0,10522538 ! positive regulation of immune effector process GO:0002699 15 15 0,000 0,08181659 0,105152 ! nitrogen compound biosynthetic process GO:0044271 86 85 1,000 0,08332716 0,10701878 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 16 16 0,000 0,08703278 0,11170014 ! negative regulation of adenylate cyclase activity GO:0007194 16 16 0,000 0,08703278 0,11162241 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! alkaloid metabolic process GO:0009820 16 16 0,000 0,08703278 0,11154479 ! regulation of synaptic plasticity GO:0048167 16 16 0,000 0,08703278 0,11146727 ! spliceosomal snRNP biogenesis GO:0000387 16 16 0,000 0,08703278 0,11138987 ! learning GO:0007612 16 16 0,000 0,08703278 0,11131257 ! circadian rhythm GO:0007623 16 16 0,000 0,08703278 0,11123537 ! inner ear morphogenesis GO:0042472 16 16 0,000 0,08703278 0,11115829 ! vacuole organization GO:0007033 16 16 0,000 0,08703278 0,11108131 ! positive regulation of cytoskeleton organization GO:0051495 16 16 0,000 0,08703278 0,11100443 ! vesicle targeting GO:0006903 17 16 0,000 0,08703278 0,11092767 ! iron ion homeostasis GO:0055072 16 16 0,000 0,08703278 0,11085101 ! regulation of systemic arterial blood pressure GO:0003073 17 16 0,000 0,08703278 0,11077445 ! cell fate specification GO:0001708 16 16 0,000 0,08703278 0,110698 ! pentose metabolic process GO:0019321 16 16 0,000 0,08703278 0,11062166 ! fatty acid transport GO:0015908 16 16 0,000 0,08703278 0,11054542 ! positive regulation of MAPKKK cascade GO:0043410 17 16 0,000 0,08703278 0,11046929 ! regulation of microtubule cytoskeleton organization GO:0070507 16 16 0,000 0,08703278 0,11039326 ! ethanolamine and derivative metabolic process GO:0042439 17 16 0,000 0,08703278 0,11031734 ! polyol metabolic process GO:0019751 16 16 0,000 0,08703278 0,11024152 ! glutamine family amino acid catabolic process GO:0009065 17 16 0,000 0,08703278 0,1101658 ! porphyrin metabolic process GO:0006778 16 16 0,000 0,08703278 0,11009019 GO:0033013|tetrapyrrole metabolic process, ! embryonic epithelial tube formation GO:0001838 17 16 0,000 0,08703278 0,11001468 GO:0001841|neural tube formation, ! regulation of JUN kinase activity GO:0043506 17 16 0,000 0,08703278 0,10993928 GO:0043507|positive regulation of JUN kinase activity, ! regulation of cell morphogenesis involved in differentiation GO:0010769 17 16 0,000 0,08703278 0,10986398 ! response to xenobiotic stimulus GO:0009410 16 16 0,000 0,08703278 0,10978878 ! regulation of coagulation GO:0050818 17 16 0,000 0,08703278 0,10971369 ! male gamete generation GO:0048232 90 88 1,000 0,08842036 0,11138669 GO:0007283|spermatogenesis, ! cellular di-, tri-valent inorganic cation homeostasis GO:0030005 89 89 1,000 0,09013876 0,11347387 ! regulation of Ras protein signal transduction GO:0046578 90 90 1,000 0,09186722 0,11557085 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 17 17 0,000 0,09222009 0,11593563 ! regulation of smooth muscle cell proliferation GO:0048660 17 17 0,000 0,09222009 0,1158566 ! regulation of actin filament depolymerization GO:0030834 17 17 0,000 0,09222009 0,11577768 ! phosphoinositide biosynthetic process GO:0046489 17 17 0,000 0,09222009 0,11569886 ! regulation of transmembrane transport GO:0034762 17 17 0,000 0,09222009 0,11562015 ! leukocyte adhesion GO:0007159 17 17 0,000 0,09222009 0,11554155 ! sensory perception of smell GO:0007608 17 17 0,000 0,09222009 0,11546306 ! glucose transport GO:0015758 17 17 0,000 0,09222009 0,11538468 ! tissue remodeling GO:0048771 17 17 0,000 0,09222009 0,1153064 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 17 17 0,000 0,09222009 0,11522822 ! embryonic skeletal system morphogenesis GO:0048704 17 17 0,000 0,09222009 0,11515015 ! cellular carbohydrate biosynthetic process GO:0034637 17 17 0,000 0,09222009 0,11507219 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 17 17 0,000 0,09222009 0,11499434 ! neural crest cell development GO:0014032 19 17 0,000 0,09222009 0,11491658 GO:0014033|neural crest cell differentiation, ! immune response-activating signal transduction GO:0002757 17 17 0,000 0,09222009 0,11483894 GO:0002764|immune response-regulating signal transduction, ! cell recognition GO:0008037 18 17 0,000 0,09222009 0,1147614 ! positive regulation of protein secretion GO:0050714 17 17 0,000 0,09222009 0,11468396 ! regulation of osteoblast differentiation GO:0045667 17 17 0,000 0,09222009 0,11460663 ! pyridine nucleotide metabolic process GO:0019362 17 17 0,000 0,09222009 0,1145294 ! myeloid leukocyte activation GO:0002274 18 17 0,000 0,09222009 0,11445227 ! adult locomotory behavior GO:0008344 17 17 0,000 0,09222009 0,11437525 ! embryonic organ development GO:0048568 17 17 0,000 0,09222009 0,11429834 ! regulation of calcium ion transport GO:0051924 17 17 0,000 0,09222009 0,11422152 ! liver development GO:0001889 17 17 0,000 0,09222009 0,11414481 ! gene silencing GO:0016458 17 17 0,000 0,09222009 0,11406821 ! di-, tri-valent inorganic cation homeostasis GO:0055066 91 91 1,000 0,09360558 0,11570428 ! DNA replication GO:0006260 91 91 1,000 0,09360558 0,11562673 ! fatty acid metabolic process GO:0006631 93 92 1,000 0,09535367 0,11770717 ! tissue morphogenesis GO:0048729 94 93 1,000 0,09711133 0,11979664 ! mRNA export from nucleus GO:0006406 18 18 0,000 0,09737868 0,1200461 ! regulation of cell projection organization GO:0031344 19 18 0,000 0,09737868 0,11996585 ! icosanoid biosynthetic process GO:0046456 18 18 0,000 0,09737868 0,11988571 ! regulation of metal ion transport GO:0010959 18 18 0,000 0,09737868 0,11980568 ! membrane docking GO:0022406 18 18 0,000 0,09737868 0,11972576 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 18 18 0,000 0,09737868 0,11964594 ! negative regulation of response to external stimulus GO:0032102 18 18 0,000 0,09737868 0,11956623 ! hexose transport GO:0008645 18 18 0,000 0,09737868 0,11948663 GO:0015749|monosaccharide transport, ! cholesterol homeostasis GO:0042632 18 18 0,000 0,09737868 0,11940713 GO:0055092|sterol homeostasis, ! striated muscle contraction GO:0006941 18 18 0,000 0,09737868 0,11932773 ! negative regulation of DNA binding GO:0043392 19 18 0,000 0,09737868 0,11924845 ! ceramide metabolic process GO:0006672 18 18 0,000 0,09737868 0,11916926 GO:0046519|sphingoid metabolic process, ! ribonucleoside monophosphate metabolic process GO:0009161 18 18 0,000 0,09737868 0,11909019 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! telencephalon development GO:0021537 19 18 0,000 0,09737868 0,11901121 ! negative regulation of MAP kinase activity GO:0043407 18 18 0,000 0,09737868 0,11893235 ! BMP signaling pathway GO:0030509 18 18 0,000 0,09737868 0,11885358 ! regulation of microtubule-based process GO:0032886 18 18 0,000 0,09737868 0,11877493 ! negative regulation of catabolic process GO:0009895 18 18 0,000 0,09737868 0,11869637 ! establishment of vesicle localization GO:0051650 19 18 0,000 0,09737868 0,11861792 ! pattern specification process GO:0007389 96 94 1,000 0,09887842 0,12036521 ! cofactor metabolic process GO:0051186 95 94 1,000 0,09887842 0,12028576 ! activation of adenylate cyclase activity GO:0007190 19 19 0,000 0,10250871 0,12461975 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 19 19 0,000 0,10250871 0,12453761 GO:0006956|complement activation, ! regulation of JAK-STAT cascade GO:0046425 19 19 0,000 0,10250871 0,12445557 ! feeding behavior GO:0007631 19 19 0,000 0,10250871 0,12437363 ! regulation of endothelial cell proliferation GO:0001936 19 19 0,000 0,10250871 0,12429181 ! peroxisome organization GO:0007031 19 19 0,000 0,10250871 0,12421009 ! positive regulation of T cell proliferation GO:0042102 19 19 0,000 0,10250871 0,12412848 ! ribonucleoside metabolic process GO:0009119 19 19 0,000 0,10250871 0,12404698 ! regulation of lymphocyte mediated immunity GO:0002706 19 19 0,000 0,10250871 0,12396558 ! positive regulation of T cell differentiation GO:0045582 19 19 0,000 0,10250871 0,12388429 ! nuclear-transcribed mRNA catabolic process GO:0000956 19 19 0,000 0,10250871 0,12380311 ! hormone biosynthetic process GO:0042446 19 19 0,000 0,10250871 0,12372204 ! biogenic amine biosynthetic process GO:0042401 20 19 0,000 0,10250871 0,12364107 ! dorsal/ventral pattern formation GO:0009953 19 19 0,000 0,10250871 0,1235602 ! eye morphogenesis GO:0048592 19 19 0,000 0,10250871 0,12347944 ! regulation of cell shape GO:0008360 21 19 0,000 0,10250871 0,12339879 ! placenta development GO:0001890 19 19 0,000 0,10250871 0,12331824 ! vesicle localization GO:0051648 20 19 0,000 0,10250871 0,1232378 ! posttranscriptional regulation of gene expression GO:0010608 98 98 1,000 0,10603784 0,12739749 ! negative regulation of cell adhesion GO:0007162 21 20 0,000 0,10761032 0,12920249 ! establishment or maintenance of cell polarity GO:0007163 21 20 0,000 0,10761032 0,12911837 ! negative regulation of binding GO:0051100 21 20 0,000 0,10761032 0,12903437 ! cytoskeleton-dependent intracellular transport GO:0030705 20 20 0,000 0,10761032 0,12895047 ! neural tube development GO:0021915 21 20 0,000 0,10761032 0,12886668 ! nucleus organization GO:0006997 20 20 0,000 0,10761032 0,128783 ! phagocytosis GO:0006909 21 20 0,000 0,10761032 0,12869943 ! unsaturated fatty acid biosynthetic process GO:0006636 20 20 0,000 0,10761032 0,12861597 ! protein targeting to membrane GO:0006612 22 20 0,000 0,10761032 0,12853261 ! cyclic nucleotide metabolic process GO:0009187 20 20 0,000 0,10761032 0,12844936 ! chromatin remodeling GO:0006338 20 20 0,000 0,10761032 0,12836623 ! detection of abiotic stimulus GO:0009582 21 20 0,000 0,10761032 0,12828319 ! RNA modification GO:0009451 20 20 0,000 0,10761032 0,12820027 ! single fertilization GO:0007338 21 20 0,000 0,10761032 0,12811745 ! regulation of B cell activation GO:0050864 20 20 0,000 0,10761032 0,12803474 ! response to other organism GO:0051707 101 100 1,000 0,10967007 0,13040125 ! mRNA catabolic process GO:0006402 21 21 0,000 0,11268367 0,13389814 ! positive regulation of adenylate cyclase activity GO:0045762 21 21 0,000 0,11268367 0,13381186 GO:0051349|positive regulation of lyase activity, GO:0031281|positive regulation of cyclase activity, ! protein amino acid lipidation GO:0006497 21 21 0,000 0,11268367 0,1337257 ! receptor-mediated endocytosis GO:0006898 21 21 0,000 0,11268367 0,13363964 ! Notch signaling pathway GO:0007219 22 21 0,000 0,11268367 0,1335537 ! morphogenesis of embryonic epithelium GO:0016331 22 21 0,000 0,11268367 0,13346787 ! ear morphogenesis GO:0042471 21 21 0,000 0,11268367 0,13338215 ! organic anion transport GO:0015711 21 21 0,000 0,11268367 0,13329654 ! cholesterol transport GO:0030301 21 21 0,000 0,11268367 0,13321104 GO:0015918|sterol transport, ! spliceosome assembly GO:0000245 22 21 0,000 0,11268367 0,13312565 ! regulation of Rab protein signal transduction GO:0032483 21 21 0,000 0,11268367 0,13304036 GO:0032313|regulation of Rab GTPase activity, ! regulation of protein import into nucleus GO:0042306 21 21 0,000 0,11268367 0,13295519 ! regulation of leukocyte mediated immunity GO:0002703 21 21 0,000 0,11268367 0,13287013 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 21 21 0,000 0,11268367 0,13278517 ! regulation of proteolysis GO:0030162 21 21 0,000 0,11268367 0,13270032 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 21 21 0,000 0,11268367 0,13261559 ! negative regulation of protein transport GO:0051224 21 21 0,000 0,11268367 0,13253096 ! RNA export from nucleus GO:0006405 22 22 0,000 0,11772892 0,13837653 ! cellular amide metabolic process GO:0043603 22 22 0,000 0,11772892 0,13828833 ! regulation of ion transport GO:0043269 22 22 0,000 0,11772892 0,13820025 ! odontogenesis GO:0042476 22 22 0,000 0,11772892 0,13811228 ! positive regulation of lymphocyte proliferation GO:0050671 22 22 0,000 0,11772892 0,13802442 GO:0032946|positive regulation of mononuclear cell proliferation, GO:0070665|positive regulation of leukocyte proliferation, GO:0070668|positive regulation of mast cell proliferation, ! embryonic skeletal system development GO:0048706 22 22 0,000 0,11772892 0,13793668 ! maintenance of protein location in cell GO:0032507 23 22 0,000 0,11772892 0,13784904 ! pigment biosynthetic process GO:0046148 22 22 0,000 0,11772892 0,13776152 ! cell chemotaxis GO:0060326 23 22 0,000 0,11772892 0,13767411 GO:0030595|leukocyte chemotaxis, ! respiratory gaseous exchange GO:0007585 22 22 0,000 0,11772892 0,13758681 ! sterol biosynthetic process GO:0016126 22 22 0,000 0,11772892 0,13749962 ! regulation of adaptive immune response GO:0002819 22 22 0,000 0,11772892 0,13741254 ! detection of external stimulus GO:0009581 23 22 0,000 0,11772892 0,13732557 ! regulation of Wnt receptor signaling pathway GO:0030111 23 22 0,000 0,11772892 0,13723871 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 22 22 0,000 0,11772892 0,13715196 ! positive regulation of lymphocyte differentiation GO:0045621 22 22 0,000 0,11772892 0,13706532 ! cytokine production GO:0001816 22 22 0,000 0,11772892 0,13697878 ! pyrimidine nucleotide metabolic process GO:0006220 22 22 0,000 0,11772892 0,13689236 ! epithelial cell differentiation GO:0030855 23 23 0,000 0,12274621 0,14263636 ! viral infectious cycle GO:0019058 23 23 0,000 0,12274621 0,14254648 ! negative regulation of protein complex disassembly GO:0043242 23 23 0,000 0,12274621 0,14245671 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 23 23 0,000 0,12274621 0,14236706 ! induction of apoptosis by extracellular signals GO:0008624 23 23 0,000 0,12274621 0,14227752 ! regulation of ARF protein signal transduction GO:0032012 23 23 0,000 0,12274621 0,1421881 ! endocrine system development GO:0035270 23 23 0,000 0,12274621 0,14209878 ! lipoprotein biosynthetic process GO:0042158 23 23 0,000 0,12274621 0,14200958 ! lipid homeostasis GO:0055088 23 23 0,000 0,12274621 0,14192049 ! Rho protein signal transduction GO:0007266 24 23 0,000 0,12274621 0,14183151 ! regulation of JNK cascade GO:0046328 25 23 0,000 0,12274621 0,14174264 ! cell projection assembly GO:0030031 25 23 0,000 0,12274621 0,14165389 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 26 24 0,000 0,12773569 0,1473197 ! heterocycle biosynthetic process GO:0018130 24 24 0,000 0,12773569 0,14722757 ! nucleotide catabolic process GO:0009166 24 24 0,000 0,12773569 0,14713555 ! fertilization GO:0009566 25 24 0,000 0,12773569 0,14704365 ! maintenance of protein location GO:0045185 25 24 0,000 0,12773569 0,14695186 ! oxidoreduction coenzyme metabolic process GO:0006733 24 24 0,000 0,12773569 0,14686019 ! regulation of actin filament polymerization GO:0030833 25 25 0,000 0,13269752 0,15246978 ! protein amino acid N-linked glycosylation GO:0006487 25 25 0,000 0,13269752 0,15237479 ! sensory perception of chemical stimulus GO:0007606 25 25 0,000 0,13269752 0,15227991 ! cellular component disassembly GO:0022411 26 25 0,000 0,13269752 0,15218515 ! endosome transport GO:0016197 25 25 0,000 0,13269752 0,15209051 ! polysaccharide biosynthetic process GO:0000271 25 25 0,000 0,13269752 0,15199598 ! excretion GO:0007588 25 25 0,000 0,13269752 0,15190157 ! generation of a signal involved in cell-cell signaling GO:0003001 27 25 0,000 0,13269752 0,15180728 ! gastrulation GO:0007369 25 25 0,000 0,13269752 0,15171311 ! regulation of endocytosis GO:0030100 25 25 0,000 0,13269752 0,15161905 ! JAK-STAT cascade GO:0007259 26 25 0,000 0,13269752 0,15152511 ! positive regulation of cytokine production GO:0001819 25 25 0,000 0,13269752 0,15143129 ! positive regulation of defense response GO:0031349 26 26 0,000 0,13763185 0,15696503 ! transforming growth factor beta receptor signaling pathway GO:0007179 26 26 0,000 0,13763185 0,15686796 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 26 26 0,000 0,13763185 0,15677101 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 26 26 0,000 0,13763185 0,15667418 ! cellular defense response GO:0006968 26 26 0,000 0,13763185 0,15657747 ! positive regulation of cytokine biosynthetic process GO:0042108 26 26 0,000 0,13763185 0,15648087 ! regulation of protein secretion GO:0050708 26 26 0,000 0,13763185 0,1563844 ! regulation of blood vessel size GO:0050880 27 26 0,000 0,13763185 0,15628804 GO:0035150|regulation of tube size, ! maintenance of location in cell GO:0051651 27 26 0,000 0,13763185 0,15619181 ! chloride transport GO:0006821 27 27 0,000 0,14253881 0,16166095 ! regulation of neurotransmitter levels GO:0001505 31 27 0,000 0,14253881 0,16156152 ! learning or memory GO:0007611 28 27 0,000 0,14253881 0,16146222 ! monocarboxylic acid transport GO:0015718 27 27 0,000 0,14253881 0,16136304 ! cAMP-mediated signaling GO:0019933 27 27 0,000 0,14253881 0,16126399 ! peptide metabolic process GO:0006518 29 27 0,000 0,14253881 0,16116505 ! inner ear development GO:0048839 27 27 0,000 0,14253881 0,16106624 ! defense response to bacterium GO:0042742 27 27 0,000 0,14253881 0,16096755 ! isoprenoid metabolic process GO:0006720 27 27 0,000 0,14253881 0,16086897 ! glutamine family amino acid metabolic process GO:0009064 28 27 0,000 0,14253881 0,16077052 ! cell growth GO:0016049 27 27 0,000 0,14253881 0,16067219 ! tRNA aminoacylation for protein translation GO:0006418 28 28 0,000 0,14741857 0,16607117 GO:0043038|amino acid activation, GO:0043039|tRNA aminoacylation, ! stress-activated protein kinase signaling pathway GO:0031098 28 28 0,000 0,14741857 0,16596972 GO:0007254|JNK cascade, ! neuromuscular process GO:0050905 28 28 0,000 0,14741857 0,16586839 ! carbohydrate transport GO:0008643 28 28 0,000 0,14741857 0,16576719 ! regulation of muscle contraction GO:0006937 28 28 0,000 0,14741857 0,16566612 ! sulfur compound biosynthetic process GO:0044272 28 28 0,000 0,14741857 0,16556516 ! keratinocyte differentiation GO:0030216 28 28 0,000 0,14741857 0,16546433 ! cartilage development GO:0051216 29 28 0,000 0,14741857 0,16536362 ! glycerophospholipid biosynthetic process GO:0046474 30 29 0,000 0,15227127 0,17070313 ! phosphoinositide metabolic process GO:0030384 29 29 0,000 0,15227127 0,17059936 ! leukocyte migration GO:0050900 30 29 0,000 0,15227127 0,17049572 ! antigen processing and presentation GO:0019882 29 29 0,000 0,15227127 0,1703922 ! DNA-dependent DNA replication GO:0006261 29 29 0,000 0,15227127 0,1702888 ! tRNA processing GO:0008033 29 29 0,000 0,15227127 0,17018554 ! adult behavior GO:0030534 30 29 0,000 0,15227127 0,17008239 ! regulation of protein polymerization GO:0032271 29 29 0,000 0,15227127 0,16997938 ! transition metal ion transport GO:0000041 31 30 0,000 0,15709705 0,17526021 ! RNA catabolic process GO:0006401 30 30 0,000 0,15709705 0,17515418 ! ER to Golgi vesicle-mediated transport GO:0006888 30 30 0,000 0,15709705 0,17504828 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 30 30 0,000 0,15709705 0,17494252 ! neuropeptide signaling pathway GO:0007218 30 30 0,000 0,15709705 0,17483687 ! regulation of protein complex disassembly GO:0043244 30 30 0,000 0,15709705 0,17473136 ! positive regulation of response to external stimulus GO:0032103 30 30 0,000 0,15709705 0,17462597 ! positive regulation of protein amino acid phosphorylation GO:0001934 30 30 0,000 0,15709705 0,17452071 ! skeletal system morphogenesis GO:0048705 31 30 0,000 0,15709705 0,17441558 ! vascular process in circulatory system GO:0003018 31 30 0,000 0,15709705 0,17431057 ! immunoglobulin mediated immune response GO:0016064 30 30 0,000 0,15709705 0,17420569 GO:0019724|B cell mediated immunity, ! regulation of inflammatory response GO:0050727 30 30 0,000 0,15709705 0,17410094 ! water-soluble vitamin metabolic process GO:0006767 30 30 0,000 0,15709705 0,17399631 ! cellular amino acid derivative biosynthetic process GO:0042398 31 30 0,000 0,15709705 0,17389181 ! regulation of translational initiation GO:0006446 31 31 0,000 0,16189606 0,1790963 ! membrane fusion GO:0006944 31 31 0,000 0,16189606 0,17898886 ! negative regulation of cytoskeleton organization GO:0051494 32 31 0,000 0,16189606 0,17888156 ! lipoprotein metabolic process GO:0042157 31 31 0,000 0,16189606 0,17877438 ! ion transmembrane transport GO:0034220 31 31 0,000 0,16189606 0,17866733 GO:0015985|energy coupled proton transport, down electrochemical gradient, GO:0015986|ATP synthesis coupled proton transport, ! glycerolipid biosynthetic process GO:0045017 32 31 0,000 0,16189606 0,17856041 ! digestion GO:0007586 31 31 0,000 0,16189606 0,17845361 ! nucleoside metabolic process GO:0009116 31 31 0,000 0,16189606 0,17834694 ! regulation of heart contraction GO:0008016 31 31 0,000 0,16189606 0,1782404 ! sphingolipid metabolic process GO:0006665 31 31 0,000 0,16189606 0,17813399 ! camera-type eye development GO:0043010 31 31 0,000 0,16189606 0,17802771 ! extracellular matrix organization GO:0030198 31 31 0,000 0,16189606 0,17792155 ! ribonucleoprotein complex assembly GO:0022618 32 31 0,000 0,16189606 0,17781552 ! epidermal cell differentiation GO:0009913 31 31 0,000 0,16189606 0,17770961 ! cell redox homeostasis GO:0045454 32 32 0,000 0,16666844 0,18283925 ! glycosaminoglycan metabolic process GO:0030203 34 32 0,000 0,16666844 0,18273048 ! regulation of vesicle-mediated transport GO:0060627 33 32 0,000 0,16666844 0,18262184 ! cell maturation GO:0048469 32 32 0,000 0,16666844 0,18251333 ! nuclear export GO:0051168 32 32 0,000 0,16666844 0,18240495 ! protein maturation by peptide bond cleavage GO:0051605 32 32 0,000 0,16666844 0,1822967 ! maintenance of location GO:0051235 33 32 0,000 0,16666844 0,18218858 ! regulation of cellular response to stress GO:0080135 35 33 0,000 0,17141434 0,18726534 ! amino acid transport GO:0006865 33 33 0,000 0,17141434 0,18715441 ! activation of protein kinase activity GO:0032147 35 33 0,000 0,17141434 0,1870436 ! regulation of protein complex assembly GO:0043254 33 33 0,000 0,17141434 0,18693292 ! membrane lipid metabolic process GO:0006643 33 33 0,000 0,17141434 0,18682238 ! regulation of synaptic transmission GO:0050804 33 33 0,000 0,17141434 0,18671196 ! regulation of protein catabolic process GO:0042176 35 34 0,000 0,17613391 0,19173939 ! coenzyme biosynthetic process GO:0009108 34 34 0,000 0,17613391 0,1916262 ! nucleoside monophosphate biosynthetic process GO:0009124 34 34 0,000 0,17613391 0,19151315 ! negative regulation of response to stimulus GO:0048585 34 34 0,000 0,17613391 0,19140023 ! detection of stimulus GO:0051606 36 34 0,000 0,17613391 0,19128744 ! acute inflammatory response GO:0002526 35 35 0,000 0,18082727 0,19626894 ! regulation of cytokine biosynthetic process GO:0042035 35 35 0,000 0,18082727 0,19615342 ! mesoderm development GO:0007498 35 35 0,000 0,18082727 0,19603804 ! regulation of cell morphogenesis GO:0022604 38 35 0,000 0,18082727 0,19592279 ! inorganic anion transport GO:0015698 35 35 0,000 0,18082727 0,19580767 ! regulation of immune effector process GO:0002697 35 35 0,000 0,18082727 0,1956927 ! hydrogen transport GO:0006818 36 36 0,000 0,18549458 0,20062589 GO:0015992|proton transport, ! aminoglycan metabolic process GO:0006022 38 36 0,000 0,18549458 0,20050822 ! embryonic limb morphogenesis GO:0030326 36 36 0,000 0,18549458 0,20039069 GO:0035113|embryonic appendage morphogenesis, ! heterocycle catabolic process GO:0046700 36 36 0,000 0,18549458 0,20027329 ! integrin-mediated signaling pathway GO:0007229 36 36 0,000 0,18549458 0,20015604 ! regulation of transmission of nerve impulse GO:0051969 36 36 0,000 0,18549458 0,20003892 ! activation of immune response GO:0002253 36 36 0,000 0,18549458 0,19992194 ! regulation of adenylate cyclase activity GO:0045761 37 37 0,000 0,19013598 0,20480456 GO:0031279|regulation of cyclase activity, GO:0051339|regulation of lyase activity, ! lymphocyte mediated immunity GO:0002449 37 37 0,000 0,19013598 0,20468493 ! eye development GO:0001654 37 37 0,000 0,19013598 0,20456544 ! ATP synthesis coupled electron transport GO:0042773 37 37 0,000 0,19013598 0,20444609 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! cellular amino acid catabolic process GO:0009063 38 37 0,000 0,19013598 0,20432688 ! adaptive immune response GO:0002250 37 37 0,000 0,19013598 0,20420781 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! neurotransmitter transport GO:0006836 40 38 0,000 0,1947516 0,20904321 ! cellular hormone metabolic process GO:0034754 39 38 0,000 0,1947516 0,20892153 ! exocytosis GO:0006887 40 38 0,000 0,1947516 0,2088 ! regulation of neurological system process GO:0031644 38 38 0,000 0,1947516 0,2086786 ! regulation of cAMP biosynthetic process GO:0030817 39 39 0,000 0,19934158 0,21347271 ! positive regulation of protein modification process GO:0031401 39 39 0,000 0,19934158 0,21334875 ! response to unfolded protein GO:0006986 39 39 0,000 0,19934158 0,21322492 ! nucleoside monophosphate metabolic process GO:0009123 39 39 0,000 0,19934158 0,21310124 ! fatty acid biosynthetic process GO:0006633 39 39 0,000 0,19934158 0,2129777 ! cytokine-mediated signaling pathway GO:0019221 39 39 0,000 0,19934158 0,21285431 ! intracellular protein transmembrane transport GO:0065002 39 39 0,000 0,19934158 0,21273106 ! regulation of MAPKKK cascade GO:0043408 41 39 0,000 0,19934158 0,21260795 ! positive regulation of T cell activation GO:0050870 39 39 0,000 0,19934158 0,21248499 ! developmental maturation GO:0021700 39 39 0,000 0,19934158 0,21236216 ! limb development GO:0060173 39 39 0,000 0,19934158 0,21223948 GO:0048736|appendage development, GO:0035107|appendage morphogenesis, ! regulation of cAMP metabolic process GO:0030814 40 40 0,000 0,20390607 0,21697396 ! regulation of nucleotide biosynthetic process GO:0030808 41 41 0,000 0,20844521 0,221676 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! amine catabolic process GO:0009310 42 41 0,000 0,20844521 0,22154816 ! elevation of cytosolic calcium ion concentration GO:0007204 41 41 0,000 0,20844521 0,22142047 ! phospholipid biosynthetic process GO:0008654 42 41 0,000 0,20844521 0,22129292 ! leukocyte mediated immunity GO:0002443 41 41 0,000 0,20844521 0,22116552 ! regulation of Ras GTPase activity GO:0032318 41 41 0,000 0,20844521 0,22103827 ! respiratory electron transport chain GO:0022904 43 42 0,000 0,21295912 0,22569503 ! regulation of cyclic nucleotide metabolic process GO:0030799 42 42 0,000 0,21295912 0,22556532 ! cytosolic calcium ion homeostasis GO:0051480 42 42 0,000 0,21295912 0,22543576 ! protein ubiquitination GO:0016567 43 42 0,000 0,21295912 0,22530635 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 43 43 0,000 0,21744794 0,22992344 ! regulation of nucleotide metabolic process GO:0006140 43 43 0,000 0,21744794 0,22979161 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 45 44 0,000 0,22191182 0,23437449 ! mRNA transport GO:0051028 44 44 0,000 0,22191182 0,23424026 ! vitamin metabolic process GO:0006766 44 44 0,000 0,22191182 0,23410617 ! positive regulation of lymphocyte activation GO:0051251 44 44 0,000 0,22191182 0,23397225 ! homophilic cell adhesion GO:0007156 45 45 0,000 0,22635089 0,23851611 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 46 45 0,000 0,22635089 0,23837982 ! steroid biosynthetic process GO:0006694 46 45 0,000 0,22635089 0,23824368 ! protein processing GO:0016485 45 45 0,000 0,22635089 0,23810769 ! cyclic-nucleotide-mediated signaling GO:0019935 46 46 0,000 0,23076527 0,24261289 ! positive regulation of ligase activity GO:0051351 47 46 0,000 0,23076527 0,24247457 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 47 47 0,000 0,23515511 0,24694636 ! regulation of blood pressure GO:0008217 48 47 0,000 0,23515511 0,24680573 ! amine transport GO:0015837 47 47 0,000 0,23515511 0,24666526 ! calcium ion transport GO:0006816 48 48 0,000 0,23952053 0,25110145 ! glycerophospholipid metabolic process GO:0006650 49 48 0,000 0,23952053 0,25095869 ! DNA recombination GO:0006310 48 48 0,000 0,23952053 0,2508161 ! divalent metal ion transport GO:0070838 49 49 0,000 0,24386168 0,25521696 ! response to bacterium GO:0009617 50 49 0,000 0,24386168 0,25507212 ! cofactor biosynthetic process GO:0051188 49 49 0,000 0,24386168 0,25492744 ! positive regulation of cell activation GO:0050867 49 49 0,000 0,24386168 0,25478292 GO:0002696|positive regulation of leukocyte activation, ! regulation of defense response GO:0031347 50 50 0,000 0,24817867 0,25914634 ! chromatin assembly GO:0031497 50 50 0,000 0,24817867 0,2589996 GO:0006334|nucleosome assembly, ! RNA transport GO:0050658 50 50 0,000 0,24817867 0,25885302 GO:0050657|nucleic acid transport, GO:0051236|establishment of RNA localization, ! nitrogen compound catabolic process GO:0044270 51 50 0,000 0,24817867 0,25870661 ! biogenic amine metabolic process GO:0006576 52 51 0,000 0,25247165 0,26303293 ! positive regulation of immune response GO:0050778 51 51 0,000 0,25247165 0,26288432 ! rRNA metabolic process GO:0016072 51 51 0,000 0,25247165 0,26273588 GO:0006364|rRNA processing, ! protein-DNA complex assembly GO:0065004 51 51 0,000 0,25247165 0,26258761 ! ATP biosynthetic process GO:0006754 51 51 0,000 0,25247165 0,26243951 ! protein maturation GO:0051604 51 51 0,000 0,25247165 0,26229157 ! RNA localization GO:0006403 52 52 0,000 0,25674074 0,26657644 ! cholesterol metabolic process GO:0008203 52 52 0,000 0,25674074 0,26642634 ! regulation of GTPase activity GO:0043087 53 52 0,000 0,25674074 0,26627641 ! sodium ion transport GO:0006814 53 53 0,000 0,26098607 0,27052718 ! tRNA metabolic process GO:0006399 53 53 0,000 0,26098607 0,27037511 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 53 53 0,000 0,26098607 0,27022321 ! sulfur metabolic process GO:0006790 55 54 0,000 0,26520777 0,27444015 ! nucleosome organization GO:0034728 55 55 0,000 0,26940596 0,27862805 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 55 55 0,000 0,26940596 0,27847179 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! ribonucleoside triphosphate biosynthetic process GO:0009201 56 56 0,000 0,27358079 0,28262858 ! ATP metabolic process GO:0046034 57 57 0,000 0,27773236 0,28675672 ! nucleoside triphosphate biosynthetic process GO:0009142 57 57 0,000 0,27773236 0,28659616 ! innate immune response GO:0045087 58 58 0,000 0,28186082 0,29069361 ! carboxylic acid transport GO:0046942 59 59 0,000 0,28596627 0,29476278 GO:0015849|organic acid transport, ! sterol metabolic process GO:0016125 59 59 0,000 0,28596627 0,29459801 ! cellular aromatic compound metabolic process GO:0006725 60 59 0,000 0,28596627 0,29443343 ! potassium ion transport GO:0006813 60 60 0,000 0,29004886 0,29847015 ! negative regulation of cellular protein metabolic process GO:0032269 60 60 0,000 0,29004886 0,2983036 ! positive regulation of cellular protein metabolic process GO:0032270 61 61 0,000 0,2941087 0,30231028 ! lipid transport GO:0006869 62 62 0,000 0,29814591 0,30628925 ! purine ribonucleoside triphosphate metabolic process GO:0009205 62 62 0,000 0,29814591 0,30611861 ! regulation of cellular component biogenesis GO:0044087 63 62 0,000 0,29814591 0,30594817 ! di-, tri-valent inorganic cation transport GO:0015674 63 62 0,000 0,29814591 0,30577792 ! ribonucleoside triphosphate metabolic process GO:0009199 63 63 0,000 0,30216062 0,30972304 ! purine nucleoside triphosphate metabolic process GO:0009144 63 63 0,000 0,30216062 0,30955088 ! regulation of response to external stimulus GO:0032101 65 64 0,000 0,30615296 0,31346661 ! angiogenesis GO:0001525 65 64 0,000 0,30615296 0,31329256 ! positive regulation of protein metabolic process GO:0051247 64 64 0,000 0,30615296 0,3131187 ! anion transport GO:0006820 65 65 0,000 0,31012303 0,31700319 ! protein amino acid glycosylation GO:0006486 66 66 0,000 0,31407097 0,32086075 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! nucleoside triphosphate metabolic process GO:0009141 66 66 0,000 0,31407097 0,32068299 ! DNA packaging GO:0006323 66 66 0,000 0,31407097 0,32050543 ! negative regulation of protein metabolic process GO:0051248 66 66 0,000 0,31407097 0,32032806 ! Golgi vesicle transport GO:0048193 67 67 0,000 0,31799689 0,32415281 ! muscle contraction GO:0006936 67 67 0,000 0,31799689 0,32397362 ! Ras protein signal transduction GO:0007265 69 67 0,000 0,31799689 0,32379463 ! purine ribonucleotide biosynthetic process GO:0009152 68 68 0,000 0,32190092 0,32758884 ! chromatin assembly or disassembly GO:0006333 68 68 0,000 0,32190092 0,32740805 ! regulation of translation GO:0006417 69 69 0,000 0,32578316 0,33117395 ! translational elongation GO:0006414 71 71 0,000 0,3334828 0,33881411 ! oxidative phosphorylation GO:0006119 71 71 0,000 0,3334828 0,33862743 ! ribosome biogenesis GO:0042254 71 71 0,000 0,3334828 0,33844096 ! negative regulation of signal transduction GO:0009968 71 71 0,000 0,3334828 0,3382547 ! secretion by cell GO:0032940 75 72 0,000 0,33730041 0,34193876 ! muscle system process GO:0003012 72 72 0,000 0,33730041 0,34175078 ! regulation of cytokine production GO:0001817 72 72 0,000 0,33730041 0,341563 ! electron transport chain GO:0022900 75 74 0,000 0,34487184 0,34903833 ! ribonucleotide biosynthetic process GO:0009260 75 75 0,000 0,34862588 0,35264407 ! purine ribonucleotide metabolic process GO:0009150 75 75 0,000 0,34862588 0,35245063 ! negative regulation of cell communication GO:0010648 76 76 0,000 0,35235896 0,35602937 ! regulation of immune response GO:0050776 78 78 0,000 0,35976268 0,36331103 ! glycoprotein biosynthetic process GO:0009101 80 80 0,000 0,36708391 0,37050145 ! ribonucleotide metabolic process GO:0009259 83 83 0,000 0,37791304 0,38122262 ! ncRNA processing GO:0034470 83 83 0,000 0,37791304 0,38101407 ! blood vessel morphogenesis GO:0048514 84 83 0,000 0,37791304 0,38080576 ! cellular amino acid derivative metabolic process GO:0006575 87 84 0,000 0,38148246 0,38419245 ! positive regulation of response to stimulus GO:0048584 86 85 0,000 0,38503193 0,38755535 ! organophosphate metabolic process GO:0019637 87 86 0,000 0,38856155 0,39089462 GO:0006644|phospholipid metabolic process, ! purine nucleotide biosynthetic process GO:0006164 88 88 0,000 0,39556167 0,39771967 ! chemotaxis GO:0006935 90 89 0,000 0,39903238 0,40099056 GO:0042330|taxis, ! visual perception GO:0007601 93 92 0,000 0,40932842 0,41111296 GO:0050953|sensory perception of light stimulus, ! positive regulation of immune system process GO:0002684 92 92 0,000 0,40932842 0,41088904 ! regulation of response to stress GO:0080134 97 94 0,000 0,41609675 0,4174558 ! blood vessel development GO:0001568 95 94 0,000 0,41609675 0,41722868 ! vasculature development GO:0001944 97 96 0,000 0,42278949 0,4237091 ! endocytosis GO:0006897 99 98 0,000 0,42940746 0,43010758 GO:0010324|membrane invagination, ! glycoprotein metabolic process GO:0009100 99 98 0,000 0,42940746 0,42987395 ! blood circulation GO:0008015 99 98 0,000 0,42940746 0,42964058 GO:0003013|circulatory system process, ! regulation of system process GO:0044057 98 98 0,000 0,42940746 0,42940746