pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6681-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of protein export from nucleus GO:0046825 10 7 4,000 2,277E-11 5,562E-08 ! organ growth GO:0035265 15 7 4,000 2,277E-11 2,781E-08 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 6,000 7,989E-10 6,505E-07 ! negative regulation of peptide secretion GO:0002792 10 7 3,000 9,469E-09 5,783E-06 GO:0046676|negative regulation of insulin secretion, ! cell cycle checkpoint GO:0000075 145 71 6,000 1,822E-08 8,903E-06 ! regulation of lipid kinase activity GO:0043550 17 8 3,000 1,888E-08 7,687E-06 ! regulation of growth hormone secretion GO:0060123 16 8 3,000 1,888E-08 6,589E-06 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 3,000 3,387E-08 1,034E-05 ! positive regulation of MAP kinase activity GO:0043406 174 93 6,000 1,204E-07 3,268E-05 ! interphase of mitotic cell cycle GO:0051329 224 98 6,000 1,728E-07 4,222E-05 ! DNA damage checkpoint GO:0000077 78 35 4,000 3,208E-07 7,126E-05 ! negative regulation of cell growth GO:0030308 142 67 5,000 3,517E-07 7,16E-05 ! negative regulation of cell size GO:0045792 144 69 5,000 4,196E-07 7,885E-05 ! DNA integrity checkpoint GO:0031570 82 38 4,000 4,912E-07 8,571E-05 ! carbohydrate homeostasis GO:0033500 59 39 4,000 5,616E-07 9,146E-05 GO:0042593|glucose homeostasis, ! negative regulation of hormone secretion GO:0046888 26 17 3,000 6,237E-07 9,522E-05 ! negative regulation of homeostatic process GO:0032845 36 17 3,000 6,237E-07 8,962E-05 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 2,000 6,748E-07 9,159E-05 ! regulation of intracellular protein transport GO:0033157 86 42 4,000 8,215E-07 1,056E-04 ! positive regulation of hormone secretion GO:0046887 35 19 3,000 1,009E-06 1,233E-04 ! negative regulation of organelle organization GO:0010639 181 80 5,000 1,014E-06 1,179E-04 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 4,000 1,306E-06 1,451E-04 ! L-serine biosynthetic process GO:0006564 7 6 2,000 1,346E-06 1,429E-04 ! negative regulation of growth GO:0045926 168 85 5,000 1,45E-06 1,476E-04 ! cellular response to hormone stimulus GO:0032870 182 85 5,000 1,45E-06 1,417E-04 ! B cell lineage commitment GO:0002326 21 7 2,000 2,348E-06 2,206E-04 ! T cell lineage commitment GO:0002360 16 7 2,000 2,348E-06 2,124E-04 ! negative regulation of telomere maintenance GO:0032205 13 7 2,000 2,348E-06 2,048E-04 ! regulation of protein localization GO:0032880 188 97 5,000 3,147E-06 2,651E-04 ! regulation of multicellular organism growth GO:0040014 90 55 4,000 3,218E-06 2,621E-04 ! response to UV GO:0009411 120 55 4,000 3,218E-06 2,536E-04 ! negative regulation of DNA replication GO:0008156 45 25 3,000 3,231E-06 2,467E-04 ! regulation of insulin secretion GO:0050796 42 25 3,000 3,231E-06 2,392E-04 ! regulation of DNA replication GO:0006275 105 56 4,000 3,522E-06 2,531E-04 ! ER overload response GO:0006983 13 8 2,000 3,745E-06 2,614E-04 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 2,000 3,745E-06 2,541E-04 ! vesicle docking during exocytosis GO:0006904 49 26 3,000 3,806E-06 2,513E-04 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 4,000 3,848E-06 2,474E-04 ! regulation of intracellular transport GO:0032386 108 57 4,000 3,848E-06 2,411E-04 ! positive regulation of cell migration GO:0030335 137 58 4,000 4,197E-06 2,564E-04 ! regulation of chromosome organization GO:0033044 49 27 3,000 4,454E-06 2,654E-04 ! vesicle docking GO:0048278 55 28 3,000 5,18E-06 3,013E-04 ! regulation of telomere maintenance GO:0032204 17 9 2,000 5,601E-06 3,182E-04 ! DNA damage response, signal transduction GO:0042770 136 62 4,000 5,85E-06 3,248E-04 ! regulation of peptide secretion GO:0002791 52 29 3,000 5,99E-06 3,252E-04 ! response to peptide hormone stimulus GO:0043434 129 64 4,000 6,847E-06 3,637E-04 ! multicellular organism reproduction GO:0032504 123 65 4,000 7,394E-06 3,843E-04 GO:0048609|reproductive process in a multicellular organism, ! positive regulation of cell motion GO:0051272 157 65 4,000 7,394E-06 3,763E-04 ! motor axon guidance GO:0008045 22 10 2,000 7,977E-06 3,977E-04 ! protein sumoylation GO:0016925 17 10 2,000 7,977E-06 3,897E-04 ! activation of MAPK activity GO:0000187 124 67 4,000 8,588E-06 4,114E-04 ! triglyceride metabolic process GO:0006641 46 33 3,000 1,019E-05 4,787E-04 ! L-serine metabolic process GO:0006563 21 11 2,000 1,093E-05 5,04E-04 ! negative regulation of secretion GO:0051048 68 35 3,000 1,295E-05 5,86E-04 ! negative regulation of DNA metabolic process GO:0051053 65 35 3,000 1,295E-05 5,754E-04 ! membrane docking GO:0022406 69 35 3,000 1,295E-05 5,651E-04 ! neutral lipid metabolic process GO:0006638 54 38 3,000 1,809E-05 7,752E-04 GO:0006639|acylglycerol metabolic process, ! glycerol ether metabolic process GO:0006662 57 40 3,000 2,225E-05 9,373E-04 ! response to gamma radiation GO:0010332 30 14 2,000 2,391E-05 9,898E-04 ! serine family amino acid biosynthetic process GO:0009070 19 14 2,000 2,391E-05 9,734E-04 ! release of cytochrome c from mitochondria GO:0001836 31 14 2,000 2,391E-05 9,574E-04 ! regulation of hormone secretion GO:0046883 69 41 3,000 2,458E-05 9,685E-04 ! organic ether metabolic process GO:0018904 59 42 3,000 2,708E-05 1,05E-03 ! hormone-mediated signaling GO:0009755 84 43 3,000 2,976E-05 1,136E-03 ! regulation of protein transport GO:0051223 165 87 4,000 3,076E-05 1,156E-03 GO:0070201|regulation of establishment of protein localization, ! response to reactive oxygen species GO:0000302 75 44 3,000 3,263E-05 1,208E-03 ! negative regulation of cell cycle process GO:0010948 35 17 2,000 4,426E-05 1,614E-03 ! regulation of DNA metabolic process GO:0051052 188 97 4,000 5,192E-05 1,865E-03 ! epidermis morphogenesis GO:0048730 43 18 2,000 5,295E-05 1,875E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 2,000 5,295E-05 1,848E-03 ! cellular pigmentation GO:0033059 37 19 2,000 6,269E-05 2,157E-03 ! apoptotic mitochondrial changes GO:0008637 42 20 2,000 7,353E-05 2,495E-03 ! peptidyl-serine phosphorylation GO:0018105 44 20 2,000 7,353E-05 2,461E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 2,000 8,552E-05 2,823E-03 ! cell aging GO:0007569 48 22 2,000 9,873E-05 3,216E-03 ! peptidyl-serine modification GO:0018209 50 22 2,000 9,873E-05 3,174E-03 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 2,000 9,873E-05 3,132E-03 ! positive regulation of secretion GO:0051047 110 61 3,000 1,188E-04 3,722E-03 ! regulation of homeostatic process GO:0032844 148 62 3,000 1,266E-04 3,916E-03 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 2,000 1,29E-04 3,939E-03 ! response to corticosteroid stimulus GO:0031960 46 24 2,000 1,29E-04 3,89E-03 ! negative regulation of phosphorylation GO:0042326 52 24 2,000 1,29E-04 3,843E-03 ! protein amino acid autophosphorylation GO:0046777 157 64 3,000 1,433E-04 4,218E-03 ! protein tetramerization GO:0051262 57 25 2,000 1,461E-04 4,25E-03 ! regulation of lipid metabolic process GO:0019216 132 66 3,000 1,615E-04 4,643E-03 ! pyruvate metabolic process GO:0006090 43 26 2,000 1,647E-04 4,678E-03 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 2,000 1,647E-04 4,625E-03 GO:0045936|negative regulation of phosphate metabolic process, ! response to endoplasmic reticulum stress GO:0034976 46 26 2,000 1,647E-04 4,572E-03 ! telomere organization GO:0032200 46 26 2,000 1,647E-04 4,521E-03 GO:0000723|telomere maintenance, ! positive regulation of muscle development GO:0048636 15 5 1,000 1,662E-04 4,512E-03 GO:0045844|positive regulation of striated muscle development, ! positive regulation of glycolysis GO:0045821 13 5 1,000 1,662E-04 4,462E-03 ! regulation of phospholipase A2 activity GO:0032429 15 5 1,000 1,662E-04 4,414E-03 ! peptidyl-threonine phosphorylation GO:0018107 20 5 1,000 1,662E-04 4,366E-03 ! homeostasis of number of cells within a tissue GO:0048873 12 5 1,000 1,662E-04 4,32E-03 ! meiotic chromosome segregation GO:0045132 10 5 1,000 1,662E-04 4,274E-03 ! B cell homeostasis GO:0001782 13 5 1,000 1,662E-04 4,23E-03 ! regulation of telomerase activity GO:0051972 7 5 1,000 1,662E-04 4,186E-03 ! regulation of mitochondrial depolarization GO:0051900 14 5 1,000 1,662E-04 4,144E-03 ! hemopoietic progenitor cell differentiation GO:0002244 14 5 1,000 1,662E-04 4,102E-03 ! protein insertion into membrane GO:0051205 17 5 1,000 1,662E-04 4,061E-03 ! phospholipid scrambling GO:0017121 8 5 1,000 1,662E-04 4,02E-03 ! acetyl-CoA metabolic process GO:0006084 41 27 2,000 1,847E-04 4,424E-03 ! insulin receptor signaling pathway GO:0008286 66 27 2,000 1,847E-04 4,381E-03 ! mitochondrial membrane organization GO:0007006 60 27 2,000 1,847E-04 4,339E-03 ! regulation of fibroblast proliferation GO:0048145 56 28 2,000 2,063E-04 4,799E-03 ! ER-nuclear signaling pathway GO:0006984 52 29 2,000 2,294E-04 5,286E-03 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 1,000 2,487E-04 5,677E-03 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! establishment of spindle localization GO:0051293 16 6 1,000 2,487E-04 5,625E-03 GO:0051653|spindle localization, ! neural nucleus development GO:0048857 19 6 1,000 2,487E-04 5,573E-03 ! enucleate erythrocyte differentiation GO:0043353 14 6 1,000 2,487E-04 5,522E-03 ! regulation of myeloid cell apoptosis GO:0033032 14 6 1,000 2,487E-04 5,473E-03 ! negative regulation of neuroblast proliferation GO:0007406 25 6 1,000 2,487E-04 5,424E-03 ! negative regulation of transferase activity GO:0051348 155 74 3,000 2,514E-04 5,436E-03 ! cellular response to extracellular stimulus GO:0031668 52 31 2,000 2,805E-04 6,01E-03 ! response to ionizing radiation GO:0010212 74 33 2,000 3,384E-04 7,189E-03 ! regulation of helicase activity GO:0051095 16 7 1,000 3,472E-04 7,312E-03 ! N-terminal protein amino acid acetylation GO:0006474 14 7 1,000 3,472E-04 7,249E-03 ! oxaloacetate metabolic process GO:0006107 13 7 1,000 3,472E-04 7,188E-03 ! male sex determination GO:0030238 15 7 1,000 3,472E-04 7,127E-03 ! spindle checkpoint GO:0031577 16 7 1,000 3,472E-04 7,068E-03 ! G1 DNA damage checkpoint GO:0031571 20 7 1,000 3,472E-04 7,01E-03 ! negative regulation of nuclear division GO:0051784 15 7 1,000 3,472E-04 6,952E-03 GO:0045839|negative regulation of mitosis, ! peptidyl-threonine modification GO:0018210 26 7 1,000 3,472E-04 6,896E-03 ! regulation of protein homodimerization activity GO:0043496 18 7 1,000 3,472E-04 6,84E-03 ! response to hydrogen peroxide GO:0042542 56 34 2,000 3,7E-04 7,232E-03 ! serine family amino acid metabolic process GO:0009069 56 34 2,000 3,7E-04 7,174E-03 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 2,000 3,7E-04 7,118E-03 ! exocytosis GO:0006887 153 83 3,000 3,902E-04 7,448E-03 ! response to drug GO:0042493 149 83 3,000 3,902E-04 7,39E-03 ! regulation of striated muscle tissue development GO:0016202 81 35 2,000 4,035E-04 7,583E-03 ! negative regulation of transport GO:0051051 164 85 3,000 4,273E-04 7,968E-03 ! regulation of muscle development GO:0048634 82 36 2,000 4,389E-04 8,122E-03 ! mitotic sister chromatid segregation GO:0000070 63 36 2,000 4,389E-04 8,061E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 1,000 4,617E-04 8,417E-03 ! pigment granule organization GO:0048753 17 8 1,000 4,617E-04 8,354E-03 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 4,617E-04 8,293E-03 ! regulation of pigmentation during development GO:0048070 25 8 1,000 4,617E-04 8,232E-03 ! melanin metabolic process GO:0006582 17 8 1,000 4,617E-04 8,173E-03 ! response to UV-B GO:0010224 17 8 1,000 4,617E-04 8,114E-03 ! regulation of T cell differentiation in the thymus GO:0033081 14 8 1,000 4,617E-04 8,056E-03 ! response to tumor cell GO:0002347 16 8 1,000 4,617E-04 7,999E-03 ! regulation of respiratory burst GO:0060263 12 8 1,000 4,617E-04 7,942E-03 ! sister chromatid segregation GO:0000819 65 37 2,000 4,762E-04 8,135E-03 ! positive regulation of DNA metabolic process GO:0051054 77 38 2,000 5,154E-04 8,744E-03 ! cellular response to insulin stimulus GO:0032869 85 38 2,000 5,154E-04 8,684E-03 ! response to inorganic substance GO:0010035 173 90 3,000 5,307E-04 8,88E-03 ! gland development GO:0048732 220 91 3,000 5,533E-04 9,196E-03 ! mitotic cell cycle checkpoint GO:0007093 76 39 2,000 5,567E-04 9,189E-03 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 5,92E-04 9,706E-03 ! regulation of glycolysis GO:0006110 20 9 1,000 5,92E-04 9,641E-03 ! microtubule bundle formation GO:0001578 22 9 1,000 5,92E-04 9,577E-03 ! T cell selection GO:0045058 27 9 1,000 5,92E-04 9,514E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 1,000 5,92E-04 9,452E-03 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 1,000 5,92E-04 9,391E-03 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 1,000 5,92E-04 9,33E-03 ! regulation of mitochondrial membrane potential GO:0051881 19 9 1,000 5,92E-04 9,27E-03 ! regulation of macrophage differentiation GO:0045649 16 9 1,000 5,92E-04 9,211E-03 ! mammary gland development GO:0030879 93 40 2,000 6E-04 9,278E-03 ! multicellular organismal metabolic process GO:0044236 64 41 2,000 6,455E-04 9,917E-03 ! T cell differentiation GO:0030217 93 42 2,000 6,93E-04 0,01058168 ! regulation of developmental growth GO:0048638 16 10 1,000 7,379E-04 0,01119758 ! positive regulation of B cell proliferation GO:0030890 18 10 1,000 7,379E-04 0,01112846 ! B cell proliferation GO:0042100 19 10 1,000 7,379E-04 0,01106018 ! alpha-beta T cell differentiation GO:0046632 24 10 1,000 7,379E-04 0,01099274 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 1,000 7,379E-04 0,01092612 GO:0043470|regulation of carbohydrate catabolic process, ! response to nicotine GO:0035094 20 10 1,000 7,379E-04 0,0108603 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 1,000 7,379E-04 0,01079527 ! regulation of smooth muscle cell migration GO:0014910 27 10 1,000 7,379E-04 0,01073101 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 1,000 7,379E-04 0,01066751 ! pathogenesis GO:0009405 17 10 1,000 7,379E-04 0,01060476 ! negative regulation of striated muscle development GO:0045843 26 10 1,000 7,379E-04 0,01054275 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 1,000 7,379E-04 0,01048145 ! protein heterooligomerization GO:0051291 17 10 1,000 7,379E-04 0,01042087 ! neuron migration GO:0001764 85 43 2,000 7,428E-04 0,01042871 ! hormone metabolic process GO:0042445 171 100 3,000 7,89E-04 0,01101482 ! regulation of epithelial cell proliferation GO:0050678 122 45 2,000 8,49E-04 0,01178402 ! induction of apoptosis by intracellular signals GO:0008629 95 45 2,000 8,49E-04 0,01171744 ! B cell differentiation GO:0030183 124 45 2,000 8,49E-04 0,01165162 ! negative regulation of muscle development GO:0048635 27 11 1,000 8,995E-04 0,01227652 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 1,000 8,995E-04 0,01220832 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 1,000 8,995E-04 0,01214087 ! peptide or protein amino-terminal blocking GO:0018409 22 11 1,000 8,995E-04 0,01207416 ! telomere maintenance via telomerase GO:0007004 24 11 1,000 8,995E-04 0,01200818 GO:0010833|telomere maintenance via telomere lengthening, ! regulation of intracellular pH GO:0051453 21 11 1,000 8,995E-04 0,01194292 ! adult heart development GO:0007512 16 11 1,000 8,995E-04 0,01187837 ! behavioral fear response GO:0001662 27 11 1,000 8,995E-04 0,0118145 GO:0002209|behavioral defense response, ! negative regulation of ossification GO:0030279 27 11 1,000 8,995E-04 0,01175132 ! alpha-beta T cell activation GO:0046631 26 11 1,000 8,995E-04 0,01168882 ! DNA methylation GO:0006306 19 11 1,000 8,995E-04 0,01162697 GO:0006305|DNA alkylation, ! apical protein localization GO:0045176 18 11 1,000 8,995E-04 0,01156578 ! thymus development GO:0048538 29 11 1,000 8,995E-04 0,01150522 ! oocyte development GO:0048599 20 11 1,000 8,995E-04 0,0114453 ! regulation of embryonic development GO:0045995 35 11 1,000 8,995E-04 0,011386 ! glycolysis GO:0006096 71 46 2,000 9,055E-04 0,01140227 ! regulation of gene-specific transcription GO:0032583 102 46 2,000 9,055E-04 0,0113438 ! pigmentation GO:0043473 103 46 2,000 9,055E-04 0,01128592 ! response to insulin stimulus GO:0032868 98 47 2,000 9,643E-04 0,01195831 ! positive regulation of cell cycle GO:0045787 96 48 2,000 1,026E-03 0,01265312 ! mitochondrial transport GO:0006839 94 48 2,000 1,026E-03 0,01258954 ! positive regulation of cellular catabolic process GO:0031331 34 12 1,000 1,077E-03 0,01314948 ! virus-host interaction GO:0019048 30 12 1,000 1,077E-03 0,01308406 ! regulation of B cell proliferation GO:0030888 22 12 1,000 1,077E-03 0,01301928 ! oligodendrocyte differentiation GO:0048709 17 12 1,000 1,077E-03 0,01295515 ! focal adhesion formation GO:0048041 37 12 1,000 1,077E-03 0,01289164 ! histone acetylation GO:0016573 27 12 1,000 1,077E-03 0,01282876 ! peptidyl-lysine modification GO:0018205 21 12 1,000 1,077E-03 0,01276648 ! T cell homeostasis GO:0043029 28 12 1,000 1,077E-03 0,01270481 ! oocyte differentiation GO:0009994 21 12 1,000 1,077E-03 0,01264373 ! negative regulation of mast cell proliferation GO:0070667 24 12 1,000 1,077E-03 0,01258323 GO:0042130|negative regulation of T cell proliferation, ! localization within membrane GO:0051668 26 12 1,000 1,077E-03 0,01252331 ! regulation of mast cell proliferation GO:0070666 89 49 2,000 1,089E-03 0,01261005 ! regulation of skeletal muscle fiber development GO:0048742 32 13 1,000 1,269E-03 0,01462118 ! plasma membrane organization GO:0007009 27 13 1,000 1,269E-03 0,01455253 ! response to X-ray GO:0010165 28 13 1,000 1,269E-03 0,01448453 ! asymmetric protein localization GO:0008105 24 13 1,000 1,269E-03 0,01441716 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 1,000 1,269E-03 0,01435041 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 35 13 1,000 1,269E-03 0,01428428 ! regulation of monooxygenase activity GO:0032768 35 13 1,000 1,269E-03 0,01421876 ! gland morphogenesis GO:0022612 31 13 1,000 1,269E-03 0,01415383 ! spleen development GO:0048536 24 13 1,000 1,269E-03 0,0140895 ! digestive tract morphogenesis GO:0048546 31 13 1,000 1,269E-03 0,01402574 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! positive regulation of homeostatic process GO:0032846 23 13 1,000 1,269E-03 0,01396257 ! cellular amino acid biosynthetic process GO:0008652 80 52 2,000 1,295E-03 0,01418401 ! histone modification GO:0016570 104 52 2,000 1,295E-03 0,01412069 ! positive regulation of growth GO:0045927 96 53 2,000 1,368E-03 0,01485685 ! regulation of leukocyte proliferation GO:0070663 97 53 2,000 1,368E-03 0,01479111 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of neuron apoptosis GO:0043523 117 53 2,000 1,368E-03 0,01472595 ! covalent chromatin modification GO:0016569 115 54 2,000 1,444E-03 0,01547738 ! epithelial tube morphogenesis GO:0060562 114 54 2,000 1,444E-03 0,01540979 ! hair follicle morphogenesis GO:0031069 27 14 1,000 1,476E-03 0,01568074 ! fear response GO:0042596 34 14 1,000 1,476E-03 0,01561286 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 1,000 1,476E-03 0,01554556 GO:0060675|ureteric bud morphogenesis, ! RNA-dependent DNA replication GO:0006278 28 14 1,000 1,476E-03 0,01547885 ! T cell differentiation in the thymus GO:0033077 37 14 1,000 1,476E-03 0,0154127 ! regulation of cellular pH GO:0030641 27 14 1,000 1,476E-03 0,01534711 ! glucose catabolic process GO:0006007 88 56 2,000 1,605E-03 0,01661084 ! nucleotide-excision repair GO:0006289 91 57 2,000 1,689E-03 0,0174075 ! regulation of skeletal muscle tissue development GO:0048641 35 15 1,000 1,699E-03 0,01743794 ! N-terminal protein amino acid modification GO:0031365 30 15 1,000 1,699E-03 0,01736498 ! negative regulation of bone remodeling GO:0046851 34 15 1,000 1,699E-03 0,01729263 ! response to cAMP GO:0051591 25 15 1,000 1,699E-03 0,01722088 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 1,000 1,699E-03 0,01714971 ! G1/S transition checkpoint GO:0031575 37 15 1,000 1,699E-03 0,01707914 ! histone deacetylation GO:0016575 24 15 1,000 1,699E-03 0,01700914 ! dopamine metabolic process GO:0042417 35 15 1,000 1,699E-03 0,01693972 ! lymphocyte homeostasis GO:0002260 33 15 1,000 1,699E-03 0,01687086 ! aging GO:0007568 112 58 2,000 1,776E-03 0,01756118 ! positive regulation of organelle organization GO:0010638 108 58 2,000 1,776E-03 0,01749037 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 1,936E-03 0,01899744 ! regulation of neurotransmitter secretion GO:0046928 35 16 1,000 1,936E-03 0,01892145 ! negative regulation of tissue remodeling GO:0034104 37 16 1,000 1,936E-03 0,01884607 ! biomineral formation GO:0031214 22 16 1,000 1,936E-03 0,01877128 ! negative regulation of leukocyte proliferation GO:0070664 32 16 1,000 1,936E-03 0,01869709 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 1,936E-03 0,01862348 ! viral reproductive process GO:0022415 132 62 2,000 2,15E-03 0,02060141 ! metencephalon development GO:0022037 32 17 1,000 2,189E-03 0,0208854 ! embryonic forelimb morphogenesis GO:0035115 31 17 1,000 2,189E-03 0,02080413 ! negative regulation of microtubule depolymerization GO:0007026 50 17 1,000 2,189E-03 0,0207235 GO:0031114|regulation of microtubule depolymerization, ! regulation of protein binding GO:0043393 33 17 1,000 2,189E-03 0,02064348 ! regulation of mitosis GO:0007088 112 63 2,000 2,251E-03 0,02115216 GO:0051783|regulation of nuclear division, ! regulation of viral genome replication GO:0045069 30 18 1,000 2,456E-03 0,02298401 ! cell-substrate junction assembly GO:0007044 56 18 1,000 2,456E-03 0,02289628 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 1,000 2,456E-03 0,02280922 ! defense response to virus GO:0051607 43 18 1,000 2,456E-03 0,02272283 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 1,000 2,456E-03 0,02263708 ! chromosome segregation GO:0007059 127 67 2,000 2,683E-03 0,02464483 ! neuromuscular junction development GO:0007528 43 19 1,000 2,737E-03 0,02504327 ! hexose catabolic process GO:0019320 113 68 2,000 2,799E-03 0,02551357 ! viral reproduction GO:0016032 142 68 2,000 2,799E-03 0,02541872 ! negative regulation of protein kinase activity GO:0006469 144 69 2,000 2,917E-03 0,02639676 ! homeostasis of number of cells GO:0048872 131 69 2,000 2,917E-03 0,02629936 ! skin development GO:0043588 42 20 1,000 3,033E-03 0,02724098 ! protein amino acid deacetylation GO:0006476 34 20 1,000 3,033E-03 0,02714119 ! protein amino acid acetylation GO:0006473 41 20 1,000 3,033E-03 0,02704214 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 1,000 3,033E-03 0,0269438 ! regulation of carbohydrate metabolic process GO:0006109 37 20 1,000 3,033E-03 0,02684618 GO:0010675|regulation of cellular carbohydrate metabolic process, ! forelimb morphogenesis GO:0035136 35 20 1,000 3,033E-03 0,02674926 ! response to alkaloid GO:0043279 38 20 1,000 3,033E-03 0,02665304 ! fatty acid beta-oxidation GO:0006635 36 20 1,000 3,033E-03 0,02655751 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 1,000 3,033E-03 0,02646266 ! negative regulation of T cell activation GO:0050868 41 20 1,000 3,033E-03 0,02636849 ! negative regulation of translation GO:0017148 32 20 1,000 3,033E-03 0,02627498 ! negative regulation of kinase activity GO:0033673 145 70 2,000 3,039E-03 0,02623341 ! B cell activation GO:0042113 179 72 2,000 3,291E-03 0,02831153 ! regulation of neurotransmitter transport GO:0051588 44 21 1,000 3,343E-03 0,02865791 ! ovarian follicle development GO:0001541 39 21 1,000 3,343E-03 0,02855771 ! prostaglandin metabolic process GO:0006693 43 21 1,000 3,343E-03 0,0284582 GO:0006692|prostanoid metabolic process, ! collagen fibril organization GO:0030199 62 21 1,000 3,343E-03 0,02835939 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 1,000 3,343E-03 0,02826126 ! hindlimb morphogenesis GO:0035137 47 22 1,000 3,668E-03 0,03089702 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 1,000 3,668E-03 0,03079084 ! cellular response to starvation GO:0009267 37 22 1,000 3,668E-03 0,0306854 ! ureteric bud development GO:0001657 50 22 1,000 3,668E-03 0,03058067 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 1,000 3,668E-03 0,03047665 ! renal system process GO:0003014 42 22 1,000 3,668E-03 0,03037334 ! G1 phase GO:0051318 44 22 1,000 3,668E-03 0,03027073 ! positive regulation of intracellular transport GO:0032388 42 22 1,000 3,668E-03 0,03016881 ! response to glucocorticoid stimulus GO:0051384 42 22 1,000 3,668E-03 0,03006757 ! positive regulation of B cell activation GO:0050871 42 22 1,000 3,668E-03 0,02996701 ! response to cytokine stimulus GO:0034097 69 22 1,000 3,668E-03 0,02986712 ! gut development GO:0048565 44 22 1,000 3,668E-03 0,02976789 ! axon guidance GO:0007411 162 75 2,000 3,693E-03 0,02987549 ! lymphocyte differentiation GO:0030098 193 76 2,000 3,833E-03 0,0309083 ! monosaccharide catabolic process GO:0046365 125 77 2,000 3,977E-03 0,03196012 ! positive regulation of DNA replication GO:0045740 44 23 1,000 4,006E-03 0,032089 ! gluconeogenesis GO:0006094 38 23 1,000 4,006E-03 0,03198413 ! viral genome replication GO:0019079 44 23 1,000 4,006E-03 0,03187995 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 1,000 4,006E-03 0,03177644 ! regeneration GO:0031099 42 23 1,000 4,006E-03 0,03167361 ! regulation of cell-matrix adhesion GO:0001952 81 23 1,000 4,006E-03 0,03157143 GO:0010810|regulation of cell-substrate adhesion, ! response to ethanol GO:0045471 47 23 1,000 4,006E-03 0,03146992 ! activation of pro-apoptotic gene products GO:0008633 51 23 1,000 4,006E-03 0,03136905 ! cellular response to reactive oxygen species GO:0034614 35 23 1,000 4,006E-03 0,03126883 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 1,000 4,006E-03 0,03116925 ! DNA modification GO:0006304 36 23 1,000 4,006E-03 0,0310703 ! acetyl-CoA catabolic process GO:0046356 37 23 1,000 4,006E-03 0,03097198 GO:0006099|tricarboxylic acid cycle, ! response to steroid hormone stimulus GO:0048545 147 79 2,000 4,274E-03 0,03293675 ! protein oligomerization GO:0051259 149 79 2,000 4,274E-03 0,03283318 ! positive regulation of cell adhesion GO:0045785 61 24 1,000 4,359E-03 0,03338006 ! regulation of cellular catabolic process GO:0031329 55 24 1,000 4,359E-03 0,03327575 ! sex determination GO:0007530 48 24 1,000 4,359E-03 0,03317209 ! regulation of viral reproduction GO:0050792 41 24 1,000 4,359E-03 0,03306907 ! oogenesis GO:0048477 44 24 1,000 4,359E-03 0,03296669 ! regulation of oxidoreductase activity GO:0051341 48 24 1,000 4,359E-03 0,03286494 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 1,000 4,359E-03 0,03276382 ! response to hypoxia GO:0001666 178 81 2,000 4,584E-03 0,03434981 ! protein import into nucleus, translocation GO:0000060 51 25 1,000 4,725E-03 0,0353001 ! positive regulation of fibroblast proliferation GO:0048146 48 25 1,000 4,725E-03 0,03519247 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 1,000 4,725E-03 0,03508551 ! dicarboxylic acid metabolic process GO:0043648 48 25 1,000 4,725E-03 0,03497919 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 1,000 4,725E-03 0,03487351 ! interaction with host GO:0051701 66 25 1,000 4,725E-03 0,03476847 ! lymphocyte proliferation GO:0046651 55 25 1,000 4,725E-03 0,03466406 ! leukocyte homeostasis GO:0001776 50 25 1,000 4,725E-03 0,03456027 ! response to oxygen levels GO:0070482 183 83 2,000 4,907E-03 0,03578369 ! response to metal ion GO:0010038 158 84 2,000 5,074E-03 0,03688858 ! T cell activation GO:0042110 189 84 2,000 5,074E-03 0,03677912 ! response to nutrient GO:0007584 135 84 2,000 5,074E-03 0,03667031 ! myelination GO:0042552 50 26 1,000 5,105E-03 0,03678918 ! molting cycle process GO:0022404 52 26 1,000 5,105E-03 0,03668097 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! multicellular organismal response to stress GO:0033555 61 26 1,000 5,105E-03 0,0365734 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 1,000 5,105E-03 0,03646647 ! coenzyme catabolic process GO:0009109 42 26 1,000 5,105E-03 0,03636015 ! negative regulation of cell development GO:0010721 83 26 1,000 5,105E-03 0,03625445 GO:0050768|negative regulation of neurogenesis, ! positive regulation of nuclear division GO:0051785 41 26 1,000 5,105E-03 0,03614937 GO:0045840|positive regulation of mitosis, ! neural tube closure GO:0001843 58 26 1,000 5,105E-03 0,03604489 GO:0060606|tube closure, ! tube lumen formation GO:0035148 59 27 1,000 5,499E-03 0,03871225 ! response to starvation GO:0042594 47 27 1,000 5,499E-03 0,03860101 ! response to toxin GO:0009636 49 27 1,000 5,499E-03 0,03849041 ! cellular response to oxidative stress GO:0034599 43 27 1,000 5,499E-03 0,03838043 ! cellular response to nutrient levels GO:0031669 45 27 1,000 5,499E-03 0,03827109 ! leukocyte proliferation GO:0070661 59 27 1,000 5,499E-03 0,03816236 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 55 27 1,000 5,499E-03 0,03805426 ! mitochondrion organization GO:0007005 159 87 2,000 5,594E-03 0,03860254 ! alcohol catabolic process GO:0046164 142 87 2,000 5,594E-03 0,0384938 ! amine biosynthetic process GO:0009309 146 88 2,000 5,774E-03 0,03962241 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 1,000 5,906E-03 0,04041375 ! protein amino acid acylation GO:0043543 59 28 1,000 5,906E-03 0,04030087 ! dendrite development GO:0016358 67 28 1,000 5,906E-03 0,04018861 ! base-excision repair GO:0006284 41 28 1,000 5,906E-03 0,04007697 ! peptidyl-tyrosine modification GO:0018212 57 28 1,000 5,906E-03 0,03996595 ! lipid oxidation GO:0034440 48 28 1,000 5,906E-03 0,03985555 GO:0019395|fatty acid oxidation, ! tube morphogenesis GO:0035239 194 89 2,000 5,958E-03 0,04009443 ! regulation of cell cycle process GO:0010564 161 90 2,000 6,145E-03 0,04124022 ! catechol metabolic process GO:0009712 55 29 1,000 6,326E-03 0,04234225 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! primary neural tube formation GO:0014020 61 29 1,000 6,326E-03 0,04222656 ! response to organic cyclic substance GO:0014070 58 29 1,000 6,326E-03 0,0421115 ! somitogenesis GO:0001756 52 29 1,000 6,326E-03 0,04199707 ! negative regulation of neuron apoptosis GO:0043524 69 29 1,000 6,326E-03 0,04188325 ! ossification GO:0001503 205 91 2,000 6,335E-03 0,04183003 ! bone development GO:0060348 206 92 2,000 6,529E-03 0,04299548 ! regulation of cell adhesion GO:0030155 241 92 2,000 6,529E-03 0,0428799 ! phenol metabolic process GO:0018958 56 30 1,000 6,76E-03 0,04427481 ! positive regulation of multicellular organism growth GO:0040018 55 30 1,000 6,76E-03 0,04415643 ! tissue homeostasis GO:0001894 50 30 1,000 6,76E-03 0,04403868 GO:0048871|multicellular organismal homeostasis, ! regulation of B cell activation GO:0050864 55 30 1,000 6,76E-03 0,04392156 ! regulation of membrane potential GO:0042391 179 94 2,000 6,928E-03 0,04489532 ! cell junction assembly GO:0034329 85 31 1,000 7,207E-03 0,0465772 ! ovulation cycle process GO:0022602 55 31 1,000 7,207E-03 0,0464543 ! male gonad development GO:0008584 56 31 1,000 7,207E-03 0,04633206 ! erythrocyte differentiation GO:0030218 62 31 1,000 7,207E-03 0,04621045 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 1,000 7,207E-03 0,04608948 ! ensheathment of neurons GO:0007272 64 31 1,000 7,207E-03 0,04596914 GO:0008366|axon ensheathment, ! cofactor catabolic process GO:0051187 54 31 1,000 7,207E-03 0,04584943 ! negative regulation of leukocyte activation GO:0002695 60 31 1,000 7,207E-03 0,04573034 ! fatty acid catabolic process GO:0009062 54 31 1,000 7,207E-03 0,04561187 ! response to heat GO:0009408 54 31 1,000 7,207E-03 0,04549401 ! collagen metabolic process GO:0032963 49 32 1,000 7,667E-03 0,04827235 ! spindle organization GO:0007051 50 32 1,000 7,667E-03 0,04814826 ! metanephros development GO:0001656 81 32 1,000 7,667E-03 0,0480248 ! response to mechanical stimulus GO:0009612 60 32 1,000 7,667E-03 0,04790198 ! hexose biosynthetic process GO:0019319 53 32 1,000 7,667E-03 0,04777978 ! ovulation cycle GO:0042698 57 32 1,000 7,667E-03 0,0476582 ! peripheral nervous system development GO:0007422 68 32 1,000 7,667E-03 0,04753724 ! hindbrain development GO:0030902 65 32 1,000 7,667E-03 0,04741689 ! positive regulation of catabolic process GO:0009896 72 32 1,000 7,667E-03 0,04729715 ! leukocyte differentiation GO:0002521 232 98 2,000 7,768E-03 0,04780385 ! regulation of pH GO:0006885 56 33 1,000 8,139E-03 0,04996157 ! positive regulation of gene-specific transcription GO:0043193 70 33 1,000 8,139E-03 0,04983635 ! skeletal muscle tissue development GO:0007519 223 100 2,000 8,21E-03 0,05014267 GO:0060538|skeletal muscle organ development, ! glial cell differentiation GO:0010001 67 34 1,000 8,625E-03 0,05254613 ! post-embryonic development GO:0009791 76 34 1,000 8,625E-03 0,05241542 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 1,000 9,123E-03 0,05530592 ! calcium-mediated signaling GO:0019722 67 35 1,000 9,123E-03 0,05516903 ! positive regulation of cell development GO:0010720 85 36 1,000 9,634E-03 0,05811431 ! negative regulation of hydrolase activity GO:0051346 66 36 1,000 9,634E-03 0,05797117 ! aerobic respiration GO:0009060 56 36 1,000 9,634E-03 0,05782873 ! monosaccharide biosynthetic process GO:0046364 57 36 1,000 9,634E-03 0,057687 ! odontogenesis GO:0042476 74 37 1,000 0,01015749 0,06067177 ! cell junction organization GO:0034330 96 37 1,000 0,01015749 0,06052379 ! female gonad development GO:0008585 71 37 1,000 0,01015749 0,06037653 ! androgen receptor signaling pathway GO:0030521 81 37 1,000 0,01015749 0,06022999 ! regulation of microtubule-based process GO:0032886 86 37 1,000 0,01015749 0,06008415 ! negative regulation of cell activation GO:0050866 69 37 1,000 0,01015749 0,05993902 ! meiosis I GO:0007127 74 38 1,000 0,01069316 0,06294795 ! regulation of protein stability GO:0031647 77 38 1,000 0,01069316 0,06279663 ! glycogen metabolic process GO:0005977 63 38 1,000 0,01069316 0,06264604 ! pigment metabolic process GO:0042440 87 38 1,000 0,01069316 0,06249617 ! neural tube formation GO:0001841 79 38 1,000 0,01069316 0,06234701 ! erythrocyte homeostasis GO:0034101 75 39 1,000 0,01124108 0,06538562 ! positive regulation of leukocyte proliferation GO:0070665 70 39 1,000 0,01124108 0,06523031 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! glucan metabolic process GO:0044042 64 39 1,000 0,01124108 0,06507573 GO:0006073|cellular glucan metabolic process, ! development of primary female sexual characteristics GO:0046545 80 40 1,000 0,01180114 0,06815644 GO:0046660|female sex differentiation, ! regulation of action potential in neuron GO:0019228 80 40 1,000 0,01180114 0,06799569 ! gliogenesis GO:0042063 91 41 1,000 0,01237322 0,07112419 ! mesenchymal cell development GO:0014031 94 41 1,000 0,01237322 0,07095723 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! monovalent inorganic cation homeostasis GO:0055067 72 41 1,000 0,01237322 0,07079105 ! embryonic epithelial tube formation GO:0001838 85 41 1,000 0,01237322 0,07062565 ! alcohol biosynthetic process GO:0046165 65 42 1,000 0,01295723 0,07378675 ! regulation of T cell differentiation GO:0045580 78 42 1,000 0,01295723 0,07361515 ! cytokinesis GO:0000910 84 42 1,000 0,01295723 0,07344435 ! positive regulation of transcription factor activity GO:0051091 71 43 1,000 0,01355306 0,0766438 GO:0090047|positive regulation of transcription regulator activity, ! striated muscle cell differentiation GO:0051146 91 43 1,000 0,01355306 0,07646679 ! development of primary male sexual characteristics GO:0046546 80 43 1,000 0,01355306 0,0762906 ! regulation of T cell proliferation GO:0042129 80 43 1,000 0,01355306 0,07611522 ! segmentation GO:0035282 78 43 1,000 0,01355306 0,07594065 ! regulation of myeloid cell differentiation GO:0045637 105 43 1,000 0,01355306 0,07576687 ! energy reserve metabolic process GO:0006112 76 44 1,000 0,0141606 0,07898251 ! negative regulation of protein complex disassembly GO:0043242 113 44 1,000 0,0141606 0,0788026 ! double-strand break repair GO:0006302 85 44 1,000 0,0141606 0,0786235 ! receptor-mediated endocytosis GO:0006898 98 45 1,000 0,01477974 0,08187509 ! branching morphogenesis of a tube GO:0048754 102 45 1,000 0,01477974 0,08168985 ! biopolymer methylation GO:0043414 91 45 1,000 0,01477974 0,08150545 ! female gamete generation GO:0007292 71 45 1,000 0,01477974 0,08132188 ! developmental growth GO:0048589 88 45 1,000 0,01477974 0,08113913 ! negative regulation of cell migration GO:0030336 122 46 1,000 0,01541039 0,08441164 ! positive regulation of protein transport GO:0051222 80 46 1,000 0,01541039 0,0842228 ! neural tube development GO:0021915 91 47 1,000 0,01605244 0,08753597 ! positive regulation of DNA binding GO:0043388 83 48 1,000 0,01670579 0,09089585 ! icosanoid metabolic process GO:0006690 92 48 1,000 0,01670579 0,09069386 ! male sex differentiation GO:0046661 93 48 1,000 0,01670579 0,09049276 ! methylation GO:0032259 97 48 1,000 0,01670579 0,09029256 ! response to calcium ion GO:0051592 94 49 1,000 0,01737033 0,09367705 ! regulation of lymphocyte differentiation GO:0045619 92 49 1,000 0,01737033 0,09347072 ! regulation of action potential GO:0001508 102 50 1,000 0,01804596 0,09689291 ! activation of caspase activity GO:0006919 95 50 1,000 0,01804596 0,09668042 ! regulation of ossification GO:0030278 123 50 1,000 0,01804596 0,09646887 ! regulation of gene expression, epigenetic GO:0040029 116 50 1,000 0,01804596 0,09625824 ! viral infectious cycle GO:0019058 104 51 1,000 0,01873258 0,09970303 ! response to temperature stimulus GO:0009266 84 51 1,000 0,01873258 0,09948629 ! negative regulation of immune system process GO:0002683 101 51 1,000 0,01873258 0,09927048 ! positive regulation of binding GO:0051099 88 52 1,000 0,01943009 0,10274398 ! response to estrogen stimulus GO:0043627 98 52 1,000 0,01943009 0,10252207 ! regulation of protein complex disassembly GO:0043244 127 52 1,000 0,01943009 0,10230112 ! morphogenesis of embryonic epithelium GO:0016331 106 52 1,000 0,01943009 0,10208112 ! unsaturated fatty acid metabolic process GO:0033559 98 52 1,000 0,01943009 0,10186206 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 1,000 0,01943009 0,10164394 ! morphogenesis of a branching structure GO:0001763 116 52 1,000 0,01943009 0,10142675 ! chromatin remodeling GO:0006338 122 53 1,000 0,0201384 0,10490002 ! vesicle organization GO:0016050 127 53 1,000 0,0201384 0,10467683 ! synapse organization GO:0050808 102 53 1,000 0,0201384 0,10445458 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 0,02037103 0,10543735 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 0,02037103 0,10521444 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,02037103 0,10499246 ! positive regulation of helicase activity GO:0051096 12 5 0,000 0,02037103 0,10477143 ! neuron fate determination GO:0048664 7 5 0,000 0,02037103 0,10455132 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02037103 0,10433213 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 0,02037103 0,10411387 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 0,02037103 0,10389651 ! polyol transport GO:0015791 12 5 0,000 0,02037103 0,10368006 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,02037103 0,10346451 ! response to superoxide GO:0000303 10 5 0,000 0,02037103 0,10324985 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,02037103 0,10303608 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 0,02037103 0,1028232 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 0,02037103 0,10261119 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,02037103 0,10240006 ! female meiosis GO:0007143 10 5 0,000 0,02037103 0,10218979 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 0,02037103 0,10198039 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,02037103 0,10177184 ! hypothalamus development GO:0021854 9 5 0,000 0,02037103 0,10156414 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 0,02037103 0,10135729 ! cobalt ion transport GO:0006824 11 5 0,000 0,02037103 0,10115128 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 0,02037103 0,1009461 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 0,02037103 0,10074176 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,02037103 0,10053824 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,02037103 0,10033554 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 0,02037103 0,10013366 ! embryonic camera-type eye development GO:0031076 12 5 0,000 0,02037103 0,09993259 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,02037103 0,09973232 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02037103 0,09953286 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 0,02037103 0,09933419 ! transposition GO:0032196 9 5 0,000 0,02037103 0,09913631 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 0,02037103 0,09893922 ! negative chemotaxis GO:0050919 16 5 0,000 0,02037103 0,09874291 ! positive regulation of histone modification GO:0031058 6 5 0,000 0,02037103 0,09854738 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,02037103 0,09835262 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 0,02037103 0,09815864 ! behavioral response to pain GO:0048266 10 5 0,000 0,02037103 0,09796541 ! clathrin coat assembly GO:0048268 15 5 0,000 0,02037103 0,09777294 ! Notch receptor processing GO:0007220 11 5 0,000 0,02037103 0,09758123 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02037103 0,09739027 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 0,02037103 0,09720005 ! micturition GO:0060073 9 5 0,000 0,02037103 0,09701058 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,02037103 0,09682184 ! copulation GO:0007620 9 5 0,000 0,02037103 0,09663384 ! glial cell fate commitment GO:0021781 14 5 0,000 0,02037103 0,09644657 ! protein maturation by protein folding GO:0022417 14 5 0,000 0,02037103 0,09626002 ! bioluminescence GO:0008218 9 5 0,000 0,02037103 0,09607419 ! spermidine metabolic process GO:0008216 7 5 0,000 0,02037103 0,09588907 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,02037103 0,09570467 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,02037103 0,09552098 ! apoptotic cell clearance GO:0043277 23 5 0,000 0,02037103 0,09533798 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,02037103 0,09515569 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 0,02037103 0,0949741 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,02037103 0,0947932 ! grooming behavior GO:0007625 6 5 0,000 0,02037103 0,09461298 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 0,02037103 0,09443345 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,02037103 0,0942546 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 0,02037103 0,09407642 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02037103 0,09389892 ! response to protozoan GO:0001562 13 5 0,000 0,02037103 0,09372209 ! lymph vessel development GO:0001945 10 5 0,000 0,02037103 0,09354592 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 0,02037103 0,09337041 ! endochondral ossification GO:0001958 17 5 0,000 0,02037103 0,09319556 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,02037103 0,09302136 ! single strand break repair GO:0000012 8 5 0,000 0,02037103 0,09284781 ! parathyroid gland development GO:0060017 14 5 0,000 0,02037103 0,09267491 ! anagen GO:0042640 7 5 0,000 0,02037103 0,09250265 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,02037103 0,09233104 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,02037103 0,09216005 ! cytokine secretion GO:0050663 15 5 0,000 0,02037103 0,0919897 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 0,02037103 0,09181998 ! ceramide catabolic process GO:0046514 7 5 0,000 0,02037103 0,09165088 ! skeletal myofibril assembly GO:0014866 12 5 0,000 0,02037103 0,0914824 ! smooth muscle tissue development GO:0048745 32 5 0,000 0,02037103 0,09131455 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,02037103 0,0911473 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,02037103 0,09098067 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,02037103 0,09081465 ! cardiac muscle fiber development GO:0048739 12 5 0,000 0,02037103 0,09064923 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,02037103 0,09048441 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 9 5 0,000 0,02037103 0,0903202 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,02037103 0,09015657 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 0,02037103 0,08999354 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,02037103 0,0898311 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 0,02037103 0,08966924 ! glycine biosynthetic process GO:0006545 7 5 0,000 0,02037103 0,08950796 ! microvillus organization GO:0032528 8 5 0,000 0,02037103 0,08934727 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 12 5 0,000 0,02037103 0,08918715 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 0,02037103 0,0890276 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 0,02037103 0,08886862 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 0,02037103 0,08871021 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 0,02037103 0,08855236 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 0,02037103 0,08839508 ! polyol catabolic process GO:0046174 9 5 0,000 0,02037103 0,08823835 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 0,02037103 0,08808217 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 0,02037103 0,08792655 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 0,02037103 0,08777148 ! muscle cell migration GO:0014812 8 5 0,000 0,02037103 0,08761695 ! mitochondrial fission GO:0000266 8 5 0,000 0,02037103 0,08746297 ! sister chromatid cohesion GO:0007062 15 5 0,000 0,02037103 0,08730952 ! response to tumor necrosis factor GO:0034612 10 5 0,000 0,02037103 0,08715662 ! mRNA transcription GO:0009299 10 5 0,000 0,02037103 0,08700425 ! nerve growth factor processing GO:0032455 9 5 0,000 0,02037103 0,08685241 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 0,02037103 0,08670109 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 0,02037103 0,08655031 ! anaerobic glycolysis GO:0019642 6 5 0,000 0,02037103 0,08640005 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,02037103 0,08625031 ! monocyte activation GO:0042117 10 5 0,000 0,02037103 0,08610109 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,02037103 0,08595238 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,02037103 0,08580419 ! response to food GO:0032094 6 5 0,000 0,02037103 0,0856565 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,02037103 0,08550933 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,02037103 0,08536266 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 0,02037103 0,08521649 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02037103 0,08507082 ! forebrain neuron development GO:0021884 13 5 0,000 0,02037103 0,08492565 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,02037103 0,08478097 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 0,02037103 0,08463678 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 0,02037103 0,08449309 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,02037103 0,08434988 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02037103 0,08420715 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 0,02037103 0,08406491 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 0,02037103 0,08392315 ! lipid glycosylation GO:0030259 7 5 0,000 0,02037103 0,08378187 ! nucleobase transport GO:0015851 6 5 0,000 0,02037103 0,08364106 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02037103 0,08350072 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 0,02037103 0,08336085 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 0,02037103 0,08322145 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 0,02037103 0,08308252 ! basic amino acid transport GO:0015802 12 5 0,000 0,02037103 0,08294405 ! cellular glucose homeostasis GO:0001678 6 5 0,000 0,02037103 0,08280604 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 0,02037103 0,08266849 ! actin nucleation GO:0045010 11 5 0,000 0,02037103 0,08253139 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,02037103 0,08239475 ! depurination GO:0045007 5 5 0,000 0,02037103 0,08225856 ! depyrimidination GO:0045008 10 5 0,000 0,02037103 0,08212282 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,02037103 0,08198753 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02037103 0,08185268 ! G2/M transition checkpoint GO:0031576 8 5 0,000 0,02037103 0,08171827 GO:0031572|G2/M transition DNA damage checkpoint, ! zinc ion homeostasis GO:0055069 9 5 0,000 0,02037103 0,08158431 GO:0006882|cellular zinc ion homeostasis, ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 0,02037103 0,08145078 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02037103 0,08131769 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,02037103 0,08118504 ! activated T cell proliferation GO:0050798 16 5 0,000 0,02037103 0,08105281 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,02037103 0,08092102 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 0,02037103 0,08078966 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,02037103 0,08065872 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02037103 0,0805282 ! gamma-delta T cell activation GO:0046629 6 5 0,000 0,02037103 0,08039811 ! response to arsenic GO:0046685 11 5 0,000 0,02037103 0,08026843 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 0,02037103 0,08013918 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,02037103 0,08001033 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 0,02037103 0,07988191 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 0,02037103 0,07975389 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 0,02037103 0,07962629 ! response to mercury ion GO:0046689 8 5 0,000 0,02037103 0,07949909 ! response to cadmium ion GO:0046686 7 5 0,000 0,02037103 0,07937229 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 0,02037103 0,0792459 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 0,02037103 0,07911992 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 0,02037103 0,07899433 ! bile acid biosynthetic process GO:0006699 7 5 0,000 0,02037103 0,07886914 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 0,02037103 0,07874435 ! ganglioside catabolic process GO:0006689 12 5 0,000 0,02037103 0,07861995 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,02037103 0,07849594 ! decidualization GO:0046697 11 5 0,000 0,02037103 0,07837233 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 0,02037103 0,0782491 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 0,02037103 0,07812626 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 0,02037103 0,07800381 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 0,02037103 0,07788173 ! embryonic cleavage GO:0040016 6 5 0,000 0,02037103 0,07776004 ! peroxisome fission GO:0016559 5 5 0,000 0,02037103 0,07763873 ! histone demethylation GO:0016577 13 5 0,000 0,02037103 0,0775178 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 0,02037103 0,07739724 ! mitotic recombination GO:0006312 9 5 0,000 0,02037103 0,07727706 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 0,02037103 0,07715725 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,02037103 0,07703781 ! metaphase plate congression GO:0051310 7 5 0,000 0,02037103 0,07691875 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02037103 0,07680004 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,02037103 0,07668171 ! enteric nervous system development GO:0048484 8 5 0,000 0,02037103 0,07656374 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 0,02037103 0,07644613 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 0,02037103 0,07632888 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 0,02037103 0,07621199 ! muscle cell proliferation GO:0033002 12 5 0,000 0,02037103 0,07609546 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,02037103 0,07597928 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 0,02037103 0,07586346 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 0,02037103 0,07574799 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,02037103 0,07563287 ! metaphase GO:0051323 11 5 0,000 0,02037103 0,0755181 ! melatonin biosynthetic process GO:0030187 7 5 0,000 0,02037103 0,07540368 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 0,02037103 0,0752896 ! cellular response to nutrient GO:0031670 8 5 0,000 0,02037103 0,07517587 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,02037103 0,07506249 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 0,02037103 0,07494944 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 0,02037103 0,07483673 ! regulation of hair follicle development GO:0051797 10 5 0,000 0,02037103 0,07472437 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 0,02037103 0,07461234 ! response to redox state GO:0051775 6 5 0,000 0,02037103 0,07450064 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 0,02037103 0,07438928 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 0,02037103 0,07427825 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,02037103 0,07416755 ! brown fat cell differentiation GO:0050873 7 5 0,000 0,02037103 0,07405718 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02037103 0,07394714 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 0,02037103 0,07383743 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02037103 0,07372804 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 0,02037103 0,07361898 ! striatum development GO:0021756 14 5 0,000 0,02037103 0,07351023 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 0,02037103 0,07340181 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,02037103 0,07329371 ! glial cell migration GO:0008347 10 5 0,000 0,02037103 0,07318592 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,02037103 0,07307846 ! neural plate morphogenesis GO:0001839 7 5 0,000 0,02037103 0,0729713 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,02037103 0,07286446 ! T cell activation during immune response GO:0002286 9 5 0,000 0,02037103 0,07275794 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,02037103 0,07265172 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,02037103 0,07254581 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 0,02037103 0,07244022 ! neuroprotection GO:0043526 8 5 0,000 0,02037103 0,07233492 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,02037103 0,07222994 ! regulation of sensory perception GO:0051931 8 5 0,000 0,02037103 0,07212526 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,02037103 0,07202088 GO:0046831|regulation of RNA export from nucleus, ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 0,02037103 0,0719168 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 0,02037103 0,07181303 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,02037103 0,07170955 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 0,02037103 0,07160637 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,02037103 0,07150349 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 0,02037103 0,0714009 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 0,02037103 0,07129861 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,02037103 0,07119661 ! spindle assembly GO:0051225 6 5 0,000 0,02037103 0,0710949 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,02037103 0,07099348 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,02037103 0,07089235 ! protein palmitoylation GO:0018345 12 5 0,000 0,02037103 0,07079151 ! drug metabolic process GO:0017144 7 5 0,000 0,02037103 0,07069095 ! stem cell division GO:0017145 11 5 0,000 0,02037103 0,07059068 GO:0048103|somatic stem cell division, ! organ regeneration GO:0031100 7 5 0,000 0,02037103 0,07049069 ! carnitine metabolic process GO:0009437 8 5 0,000 0,02037103 0,07039099 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,02037103 0,07029157 ! regulation of angiogenesis GO:0045765 125 54 1,000 0,0208574 0,07186829 ! activation of phospholipase C activity GO:0007202 110 54 1,000 0,0208574 0,07176707 GO:0010863|positive regulation of phospholipase C activity, ! embryonic skeletal system development GO:0048706 101 54 1,000 0,0208574 0,07166613 ! regulation of cell shape GO:0008360 142 54 1,000 0,0208574 0,07156548 ! positive regulation of phospholipase activity GO:0010518 111 55 1,000 0,02158699 0,07396495 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 1,000 0,02158699 0,07386136 ! negative regulation of cell motion GO:0051271 142 55 1,000 0,02158699 0,07375805 ! skeletal muscle fiber development GO:0048741 130 56 1,000 0,02232707 0,07618022 ! negative regulation of cytoskeleton organization GO:0051494 139 56 1,000 0,02232707 0,07607398 ! RNA elongation GO:0006354 90 56 1,000 0,02232707 0,07596802 ! regulation of bone remodeling GO:0046850 143 57 1,000 0,02307756 0,07841234 ! positive regulation of caspase activity GO:0043280 108 57 1,000 0,02307756 0,07830344 GO:0010952|positive regulation of peptidase activity, ! muscle fiber development GO:0048747 131 57 1,000 0,02307756 0,07819483 ! regulation of phospholipase activity GO:0010517 113 57 1,000 0,02307756 0,07808653 ! heart morphogenesis GO:0003007 105 57 1,000 0,02307756 0,07797853 ! regulation of actin filament length GO:0030832 118 58 1,000 0,02383835 0,08043795 ! cellular polysaccharide metabolic process GO:0044264 93 58 1,000 0,02383835 0,080327 ! regulation of tissue remodeling GO:0034103 146 58 1,000 0,02383835 0,08021636 ! positive regulation of lipase activity GO:0060193 115 58 1,000 0,02383835 0,08010602 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,02439551 0,08186569 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,02439551 0,08175339 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 0,02439551 0,0816414 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 0,02439551 0,08152971 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,02439551 0,08141834 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 0,02439551 0,08130726 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 0,02439551 0,08119649 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,02439551 0,08108602 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 0,02439551 0,08097584 ! response to oxygen radical GO:0000305 11 6 0,000 0,02439551 0,08086597 ! positive regulation of axon extension GO:0045773 13 6 0,000 0,02439551 0,0807564 ! myoblast cell fate commitment GO:0048625 18 6 0,000 0,02439551 0,08064712 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 0,02439551 0,08053814 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 0,02439551 0,08042945 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,02439551 0,08032105 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,02439551 0,08021295 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 0,02439551 0,08010514 ! forebrain regionalization GO:0021871 9 6 0,000 0,02439551 0,07999761 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,02439551 0,07989038 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,02439551 0,07978343 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 0,02439551 0,07967677 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,02439551 0,07957039 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 0,02439551 0,0794643 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 0,02439551 0,07935848 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,02439551 0,07925295 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 0,02439551 0,0791477 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 0,02439551 0,07904273 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,02439551 0,07893804 ! malate metabolic process GO:0006108 13 6 0,000 0,02439551 0,07883363 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 0,02439551 0,07872949 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 0,02439551 0,07862562 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 0,02439551 0,07852203 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 0,02439551 0,07841871 ! protein refolding GO:0042026 15 6 0,000 0,02439551 0,07831567 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,02439551 0,07821289 ! opsonization GO:0008228 8 6 0,000 0,02439551 0,07811038 ! mating behavior GO:0007617 7 6 0,000 0,02439551 0,07800814 ! erythrocyte maturation GO:0043249 8 6 0,000 0,02439551 0,07790617 ! embryonic hemopoiesis GO:0035162 16 6 0,000 0,02439551 0,07780447 ! protein amino acid dealkylation GO:0008214 15 6 0,000 0,02439551 0,07770303 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 0,02439551 0,07760185 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 0,02439551 0,07750094 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,02439551 0,07740029 ! response to interferon-gamma GO:0034341 16 6 0,000 0,02439551 0,0772999 ! toxin metabolic process GO:0009404 11 6 0,000 0,02439551 0,07719977 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,02439551 0,0770999 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 0,02439551 0,07700029 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 0,02439551 0,07690093 ! nuclear migration GO:0007097 13 6 0,000 0,02439551 0,07680183 ! cGMP-mediated signaling GO:0019934 14 6 0,000 0,02439551 0,07670299 ! dorsal spinal cord development GO:0021516 10 6 0,000 0,02439551 0,0766044 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,02439551 0,07650606 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 0,02439551 0,07640798 ! thymic T cell selection GO:0045061 16 6 0,000 0,02439551 0,07631014 ! sphingoid catabolic process GO:0046521 8 6 0,000 0,02439551 0,07621256 ! protein lipoylation GO:0009249 10 6 0,000 0,02439551 0,07611523 ! transepithelial chloride transport GO:0030321 12 6 0,000 0,02439551 0,07601814 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 0,02439551 0,0759213 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,02439551 0,07582471 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 0,02439551 0,07572836 ! glutamate catabolic process GO:0006538 12 6 0,000 0,02439551 0,07563226 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 0,02439551 0,0755364 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,02439551 0,07544079 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 0,02439551 0,07534541 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,02439551 0,07525028 ! hyperosmotic response GO:0006972 10 6 0,000 0,02439551 0,07515539 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 0,02439551 0,07506073 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 0,02439551 0,07496632 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,02439551 0,07487214 ! urea metabolic process GO:0019627 7 6 0,000 0,02439551 0,0747782 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,02439551 0,07468449 ! neutrophil activation GO:0042119 7 6 0,000 0,02439551 0,07459102 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,02439551 0,07449778 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 0,02439551 0,07440477 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,02439551 0,074312 ! paraxial mesoderm development GO:0048339 16 6 0,000 0,02439551 0,07421945 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 0,02439551 0,07412714 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,02439551 0,07403506 ! neuron apoptosis GO:0051402 15 6 0,000 0,02439551 0,0739432 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,02439551 0,07385158 ! T cell mediated immunity GO:0002456 17 6 0,000 0,02439551 0,07376018 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,02439551 0,073669 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 0,02439551 0,07357805 ! carnitine transport GO:0015879 10 6 0,000 0,02439551 0,07348733 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,02439551 0,07339682 ! positive regulation of exocytosis GO:0045921 11 6 0,000 0,02439551 0,07330655 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 0,02439551 0,07321649 ! early endosome to late endosome transport GO:0045022 16 6 0,000 0,02439551 0,07312665 ! 5S class rRNA transcription GO:0042791 13 6 0,000 0,02439551 0,07303704 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,02439551 0,07294764 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 0,02439551 0,07285846 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 0,02439551 0,0727695 ! sodium ion homeostasis GO:0055078 12 6 0,000 0,02439551 0,07268076 ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 0,02439551 0,07259223 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,02439551 0,07250392 GO:0045686|negative regulation of glial cell differentiation, ! response to UV-C GO:0010225 14 6 0,000 0,02439551 0,07241582 ! astrocyte development GO:0014002 16 6 0,000 0,02439551 0,07232794 ! protein targeting to lysosome GO:0006622 12 6 0,000 0,02439551 0,07224027 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,02439551 0,07215281 ! interaction with symbiont GO:0051702 14 6 0,000 0,02439551 0,07206556 ! regulation of dendrite development GO:0050773 16 6 0,000 0,02439551 0,07197853 ! peptidyl-arginine modification GO:0018195 13 6 0,000 0,02439551 0,0718917 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 0,02439551 0,07180509 ! response to copper ion GO:0046688 10 6 0,000 0,02439551 0,07171868 ! response to exogenous dsRNA GO:0043330 13 6 0,000 0,02439551 0,07163248 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,02439551 0,07154648 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 0,02439551 0,0714607 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,02439551 0,07137512 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 0,02439551 0,07128974 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,02439551 0,07120457 ! nucleoside catabolic process GO:0009164 10 6 0,000 0,02439551 0,0711196 ! hair follicle maturation GO:0048820 8 6 0,000 0,02439551 0,07103483 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,02439551 0,07095026 ! Schwann cell development GO:0014044 15 6 0,000 0,02439551 0,0708659 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 0,02439551 0,07078174 ! response to pheromone GO:0019236 6 6 0,000 0,02439551 0,07069777 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 0,02439551 0,07061401 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 0,02439551 0,07053044 ! base conversion or substitution editing GO:0016553 6 6 0,000 0,02439551 0,07044707 ! subpallium development GO:0021544 15 6 0,000 0,02439551 0,0703639 ! neural tube patterning GO:0021532 8 6 0,000 0,02439551 0,07028092 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 0,02439551 0,07019814 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 0,02439551 0,07011555 ! maintenance of organ identity GO:0048496 9 6 0,000 0,02439551 0,07003316 ! G2 phase GO:0051319 16 6 0,000 0,02439551 0,06995096 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 0,02439551 0,06986896 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 0,02439551 0,06978714 ! oxygen homeostasis GO:0032364 10 6 0,000 0,02439551 0,06970552 ! establishment of planar polarity GO:0001736 7 6 0,000 0,02439551 0,06962409 ! regulation of mast cell activation GO:0033003 13 6 0,000 0,02439551 0,06954285 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,02439551 0,0694618 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 0,02439551 0,06938093 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,02439551 0,06930026 ! receptor internalization GO:0031623 11 6 0,000 0,02439551 0,06921977 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 0,02439551 0,06913947 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 0,02439551 0,06905935 ! neutrophil homeostasis GO:0001780 11 6 0,000 0,02439551 0,06897942 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,02439551 0,06889968 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 0,02439551 0,06882012 ! protein deubiquitination GO:0016579 16 6 0,000 0,02439551 0,06874074 ! protein destabilization GO:0031648 9 6 0,000 0,02439551 0,06866155 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 0,02439551 0,06858253 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,02439551 0,0685037 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 0,02439551 0,06842505 ! regulation of viral transcription GO:0046782 11 6 0,000 0,02439551 0,06834658 ! progesterone metabolic process GO:0042448 12 6 0,000 0,02439551 0,06826829 ! negative regulation of axon extension GO:0030517 24 6 0,000 0,02439551 0,06819018 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 0,02439551 0,06811225 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 0,02439551 0,0680345 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,02439551 0,06795692 ! determination of adult lifespan GO:0008340 17 6 0,000 0,02439551 0,06787952 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 0,02439551 0,0678023 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 0,02439551 0,06772525 ! neural plate development GO:0001840 9 6 0,000 0,02439551 0,06764838 ! catecholamine transport GO:0051937 9 6 0,000 0,02439551 0,06757168 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 0,02439551 0,06749515 ! sensory cilium assembly GO:0035058 10 6 0,000 0,02439551 0,0674188 ! organ or tissue specific immune response GO:0002251 8 6 0,000 0,02439551 0,06734262 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 0,02439551 0,06726662 ! maternal placenta development GO:0001893 12 6 0,000 0,02439551 0,06719078 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 0,02439551 0,06711511 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,02439551 0,06703962 ! negative regulation of B cell activation GO:0050869 14 6 0,000 0,02439551 0,06696429 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 0,02439551 0,06688914 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 0,02439551 0,06681415 ! positive regulation of coagulation GO:0050820 13 6 0,000 0,02439551 0,06673933 ! cellular anion homeostasis GO:0030002 11 6 0,000 0,02439551 0,06666468 GO:0055081|anion homeostasis, ! establishment of organelle localization GO:0051656 122 59 1,000 0,02460934 0,06717387 ! lipid modification GO:0030258 112 60 1,000 0,02539044 0,06922862 ! DNA catabolic process GO:0006308 94 60 1,000 0,02539044 0,06915145 ! kidney development GO:0001822 133 60 1,000 0,02539044 0,06907444 ! regulation of cellular component size GO:0032535 125 61 1,000 0,02618156 0,07114744 ! tRNA transcription GO:0009304 17 7 0,000 0,02840356 0,07709989 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 0,02840356 0,07701432 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 0,02840356 0,07692894 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,02840356 0,07684374 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 0,02840356 0,07675874 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,02840356 0,07667392 ! sleep GO:0030431 16 7 0,000 0,02840356 0,07658929 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,02840356 0,07650485 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 0,02840356 0,07642059 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,02840356 0,07633652 ! prostate gland development GO:0030850 14 7 0,000 0,02840356 0,07625264 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,02840356 0,07616893 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,02840356 0,07608542 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,02840356 0,07600208 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,02840356 0,07591893 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,02840356 0,07583596 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,02840356 0,07575317 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,02840356 0,07567056 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,02840356 0,07558813 ! SMAD protein complex assembly GO:0007183 13 7 0,000 0,02840356 0,07550588 ! glycolipid transport GO:0046836 11 7 0,000 0,02840356 0,0754238 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,02840356 0,07534191 GO:0051923|sulfation, ! neuron adhesion GO:0007158 14 7 0,000 0,02840356 0,07526019 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,02840356 0,07517866 ! establishment of tissue polarity GO:0007164 8 7 0,000 0,02840356 0,07509729 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 0,02840356 0,07501611 ! mRNA stabilization GO:0048255 18 7 0,000 0,02840356 0,0749351 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 0,02840356 0,07485426 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 0,02840356 0,0747736 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 0,02840356 0,07469311 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 0,02840356 0,0746128 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,02840356 0,07453265 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,02840356 0,07445268 ! lipoprotein transport GO:0042953 14 7 0,000 0,02840356 0,07437288 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,02840356 0,07429325 ! rhythmic behavior GO:0007622 17 7 0,000 0,02840356 0,0742138 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 0,02840356 0,07413451 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 0,02840356 0,07405539 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,02840356 0,07397644 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 0,02840356 0,07389766 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,02840356 0,07381904 ! regulation of odontogenesis GO:0042481 14 7 0,000 0,02840356 0,07374059 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,02840356 0,07366231 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 0,02840356 0,0735842 ! mechanosensory behavior GO:0007638 16 7 0,000 0,02840356 0,07350625 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 0,02840356 0,07342847 ! positive regulation of isotype switching GO:0045830 17 7 0,000 0,02840356 0,07335085 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 0,02840356 0,07327339 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,02840356 0,0731961 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,02840356 0,07311897 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,02840356 0,073042 ! spinal cord patterning GO:0021511 14 7 0,000 0,02840356 0,07296519 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 0,02840356 0,07288855 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,02840356 0,07281207 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,02840356 0,07273574 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 0,02840356 0,07265958 ! adrenal gland development GO:0030325 17 7 0,000 0,02840356 0,07258358 ! cysteine metabolic process GO:0006534 13 7 0,000 0,02840356 0,07250773 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 0,02840356 0,07243205 ! ovulation GO:0030728 10 7 0,000 0,02840356 0,07235652 ! adenohypophysis development GO:0021984 11 7 0,000 0,02840356 0,07228115 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 0,02840356 0,07220593 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 0,02840356 0,07213087 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 0,02840356 0,07205597 ! microtubule nucleation GO:0007020 21 7 0,000 0,02840356 0,07198122 ! proline biosynthetic process GO:0006561 10 7 0,000 0,02840356 0,07190663 ! tryptophan metabolic process GO:0006568 11 7 0,000 0,02840356 0,07183219 ! thyroid hormone generation GO:0006590 13 7 0,000 0,02840356 0,07175791 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 0,02840356 0,07168378 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,02840356 0,0716098 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,02840356 0,07153598 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,02840356 0,07146231 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,02840356 0,07138879 ! galactose metabolic process GO:0006012 13 7 0,000 0,02840356 0,07131542 ! vesicle fusion GO:0006906 20 7 0,000 0,02840356 0,0712422 ! response to dietary excess GO:0002021 8 7 0,000 0,02840356 0,07116913 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,02840356 0,07109621 ! intracellular pH reduction GO:0051452 13 7 0,000 0,02840356 0,07102344 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,02840356 0,07095082 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 0,02840356 0,07087834 ! nucleoside transport GO:0015858 11 7 0,000 0,02840356 0,07080602 ! nucleoside salvage GO:0043174 11 7 0,000 0,02840356 0,07073384 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 0,02840356 0,07066181 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,02840356 0,07058993 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 0,02840356 0,07051819 ! parturition GO:0007567 16 7 0,000 0,02840356 0,0704466 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 0,02840356 0,07037515 ! rRNA modification GO:0000154 14 7 0,000 0,02840356 0,07030385 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,02840356 0,07023269 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 0,02840356 0,07016168 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,02840356 0,07009081 ! monocyte differentiation GO:0030224 16 7 0,000 0,02840356 0,07002008 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,02840356 0,0699495 ! centrosome duplication GO:0051298 14 7 0,000 0,02840356 0,06987905 ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,02840356 0,06980875 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,02840356 0,06973859 ! fibrinolysis GO:0042730 11 7 0,000 0,02840356 0,06966857 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 0,000 0,02840356 0,0695987 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,02840356 0,06952896 ! eating behavior GO:0042755 8 7 0,000 0,02840356 0,06945936 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,02840356 0,0693899 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 0,02840356 0,06932058 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 0,02840356 0,0692514 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,02840356 0,06918235 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 0,02840356 0,06911345 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,02840356 0,06904468 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 0,02840356 0,06897604 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 0,02840356 0,06890755 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 0,02840356 0,06883919 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 0,02840356 0,06877096 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,02840356 0,06870287 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 0,02840356 0,06863492 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,02840356 0,06856709 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,02840356 0,06849941 ! histone ubiquitination GO:0016574 9 7 0,000 0,02840356 0,06843185 ! regulation of meiosis GO:0040020 12 7 0,000 0,02840356 0,06836443 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 0,02840356 0,06829715 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 0,02840356 0,06822999 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,02840356 0,06816297 ! membrane to membrane docking GO:0022614 14 7 0,000 0,02840356 0,06809607 ! transcription termination GO:0006353 14 7 0,000 0,02840356 0,06802931 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,02840356 0,06796268 ! anaphase GO:0051322 18 7 0,000 0,02840356 0,06789618 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 0,02840356 0,06782981 ! axonal fasciculation GO:0007413 19 7 0,000 0,02840356 0,06776357 ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 0,02840356 0,06769746 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,02840356 0,06763148 GO:0015991|ATP hydrolysis coupled proton transport, ! diuresis GO:0030146 12 7 0,000 0,02840356 0,06756563 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,02840356 0,0674999 ! thiamin metabolic process GO:0006772 7 7 0,000 0,02840356 0,0674343 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,02840356 0,06736883 ! antibiotic transport GO:0042891 9 7 0,000 0,02840356 0,06730349 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,02840356 0,06723827 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 0,02840356 0,06717318 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 0,02840356 0,06710822 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 0,02840356 0,06704338 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,02840356 0,06697867 ! melanin biosynthetic process GO:0042438 10 7 0,000 0,02840356 0,06691408 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 0,02840356 0,06684961 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,02840356 0,06678527 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 0,02840356 0,06672106 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,02840356 0,06665696 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 0,02840356 0,06659299 ! endosome to lysosome transport GO:0008333 12 7 0,000 0,02840356 0,06652915 ! protein modification by small protein removal GO:0070646 19 7 0,000 0,02840356 0,06646542 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 0,02840356 0,06640182 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,02840356 0,06633834 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,02840356 0,06627498 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,02840356 0,06621174 ! muscle adaptation GO:0043500 13 7 0,000 0,02840356 0,06614862 ! embryonic heart tube development GO:0035050 14 7 0,000 0,02840356 0,06608562 ! retina homeostasis GO:0001895 12 7 0,000 0,02840356 0,06602274 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 0,02840356 0,06595998 ! protein amino acid prenylation GO:0018346 19 7 0,000 0,02840356 0,06589734 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 0,02840356 0,06583482 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 0,02840356 0,06577242 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 1,000 0,02944431 0,06811785 ! ear development GO:0043583 114 66 1,000 0,03028411 0,06999439 ! regulation of cytokine biosynthetic process GO:0042035 108 66 1,000 0,03028411 0,06992823 ! gonad development GO:0008406 115 66 1,000 0,03028411 0,0698622 ! steroid hormone receptor signaling pathway GO:0030518 146 66 1,000 0,03028411 0,06979629 ! embryonic limb morphogenesis GO:0030326 139 67 1,000 0,03113336 0,07168595 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 1,000 0,03113336 0,07161845 ! secondary metabolic process GO:0019748 125 67 1,000 0,03113336 0,07155108 ! myeloid cell differentiation GO:0030099 126 67 1,000 0,03113336 0,07148383 ! extracellular matrix organization GO:0030198 146 68 1,000 0,03199198 0,07338629 ! negative regulation of ligase activity GO:0051352 116 68 1,000 0,03199198 0,07331745 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! regulation of lipase activity GO:0060191 137 68 1,000 0,03199198 0,07324874 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 1,000 0,03199198 0,07318015 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,03239526 0,07403333 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,03239526 0,07396414 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 0,03239526 0,07389507 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 0,03239526 0,07382614 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,03239526 0,07375734 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,03239526 0,07368866 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,03239526 0,07362012 ! male meiosis GO:0007140 9 8 0,000 0,03239526 0,0735517 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,03239526 0,0734834 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,03239526 0,07341524 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,03239526 0,0733472 ! meiotic prophase I GO:0007128 14 8 0,000 0,03239526 0,07327928 ! response to zinc ion GO:0010043 12 8 0,000 0,03239526 0,07321149 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,03239526 0,07314383 ! oligopeptide transport GO:0006857 16 8 0,000 0,03239526 0,07307629 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,03239526 0,07300888 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,03239526 0,07294159 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,03239526 0,07287442 ! signal peptide processing GO:0006465 12 8 0,000 0,03239526 0,07280738 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,03239526 0,07274046 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,03239526 0,07267367 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,03239526 0,072607 ! succinate metabolic process GO:0006105 17 8 0,000 0,03239526 0,07254044 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,03239526 0,07247402 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,03239526 0,07240771 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,03239526 0,07234152 ! estrogen metabolic process GO:0008210 17 8 0,000 0,03239526 0,07227546 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,03239526 0,07220951 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,03239526 0,07214369 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,03239526 0,07207798 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,03239526 0,0720124 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,03239526 0,07194693 ! reflex GO:0060004 17 8 0,000 0,03239526 0,07188159 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,03239526 0,07181636 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,03239526 0,07175125 ! hemoglobin metabolic process GO:0020027 14 8 0,000 0,03239526 0,07168625 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,03239526 0,07162138 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,03239526 0,07155662 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,03239526 0,07149198 ! astrocyte differentiation GO:0048708 19 8 0,000 0,03239526 0,07142746 ! histidine catabolic process GO:0006548 10 8 0,000 0,03239526 0,07136305 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,03239526 0,07129876 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,03239526 0,07123459 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,03239526 0,07117053 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,03239526 0,07110658 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,03239526 0,07104275 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,03239526 0,07097904 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,03239526 0,07091543 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,03239526 0,07085195 ! macrophage activation GO:0042116 13 8 0,000 0,03239526 0,07078857 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,03239526 0,07072531 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,03239526 0,07066217 ! positive regulation of insulin secretion GO:0032024 17 8 0,000 0,03239526 0,07059913 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,03239526 0,07053621 ! purine salvage GO:0043101 12 8 0,000 0,03239526 0,0704734 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,03239526 0,0704107 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,03239526 0,07034811 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,03239526 0,07028564 ! osteoblast development GO:0002076 17 8 0,000 0,03239526 0,07022327 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,03239526 0,07016102 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,03239526 0,07009887 ! Schwann cell differentiation GO:0014037 21 8 0,000 0,03239526 0,07003684 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,03239526 0,06997491 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,03239526 0,0699131 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,03239526 0,06985139 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,03239526 0,06978979 ! intermediate filament organization GO:0045109 12 8 0,000 0,03239526 0,0697283 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,03239526 0,06966692 ! cellular extravasation GO:0045123 13 8 0,000 0,03239526 0,06960565 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,03239526 0,06954449 ! response to antibiotic GO:0046677 11 8 0,000 0,03239526 0,06948343 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,03239526 0,06942248 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,03239526 0,06936163 ! DNA topological change GO:0006265 12 8 0,000 0,03239526 0,0693009 ! response to tropane GO:0014073 15 8 0,000 0,03239526 0,06924027 GO:0042220|response to cocaine, ! melanosome transport GO:0032402 13 8 0,000 0,03239526 0,06917974 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,03239526 0,06911932 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,03239526 0,06905901 ! mast cell activation GO:0045576 14 8 0,000 0,03239526 0,0689988 ! multicellular organismal aging GO:0010259 20 8 0,000 0,03239526 0,0689387 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 0,03239526 0,0688787 ! gas homeostasis GO:0033483 14 8 0,000 0,03239526 0,0688188 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,03239526 0,06875901 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,03239526 0,06869933 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,03239526 0,06863974 ! nucleosome disassembly GO:0006337 14 8 0,000 0,03239526 0,06858026 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,03239526 0,06852089 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 0,03239526 0,06846161 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,03239526 0,06840244 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,03239526 0,06834337 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,03239526 0,0682844 ! intracellular lipid transport GO:0032365 16 8 0,000 0,03239526 0,06822554 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,03239526 0,06816677 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,03239526 0,06810811 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 0,03239526 0,06804955 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,03239526 0,06799109 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 0,03239526 0,06793273 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,03239526 0,06787446 ! hormone catabolic process GO:0042447 17 8 0,000 0,03239526 0,0678163 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,03239526 0,06775824 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,03239526 0,06770028 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,03239526 0,06764241 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,03239526 0,06758465 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,03239526 0,06752698 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,03239526 0,06746942 ! adult feeding behavior GO:0008343 10 8 0,000 0,03239526 0,06741195 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,03239526 0,06735457 ! ATP catabolic process GO:0006200 11 8 0,000 0,03239526 0,0672973 ! blastocyst growth GO:0001832 19 8 0,000 0,03239526 0,06724012 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,03239526 0,06718304 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,03239526 0,06712606 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,03239526 0,06706917 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,03239526 0,06701238 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,03239526 0,06695569 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,03239526 0,06689909 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,03239526 0,06684259 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,03239526 0,06678618 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,03239526 0,06672987 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 0,03239526 0,06667365 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 0,03239526 0,06661753 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,03239526 0,0665615 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,03239526 0,06650557 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 0,03239526 0,06644973 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 0,03239526 0,06639398 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,03239526 0,06633833 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,03239526 0,06628277 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 0,03239526 0,0662273 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 0,03239526 0,06617193 ! lung development GO:0030324 165 69 1,000 0,03285988 0,0670649 ! urogenital system development GO:0001655 149 69 1,000 0,03285988 0,06700892 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 1,000 0,03285988 0,06695303 ! germ cell development GO:0007281 133 70 1,000 0,03373696 0,06868284 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 1,000 0,03462315 0,07042828 ! appendage morphogenesis GO:0035107 150 72 1,000 0,03551835 0,07218912 GO:0035108|limb morphogenesis, ! respiratory tube development GO:0030323 171 72 1,000 0,03551835 0,07212912 ! actin filament organization GO:0007015 167 72 1,000 0,03551835 0,07206921 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 1,000 0,03551835 0,0720094 ! coenzyme biosynthetic process GO:0009108 119 72 1,000 0,03551835 0,07194969 ! axon extension GO:0048675 16 9 0,000 0,03637068 0,07361521 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,03637068 0,07355427 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 0,03637068 0,07349343 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,03637068 0,07343269 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,03637068 0,07337206 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,03637068 0,07331152 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,03637068 0,07325108 ! reproductive behavior GO:0019098 22 9 0,000 0,03637068 0,07319074 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,03637068 0,0731305 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 0,03637068 0,07307036 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 0,03637068 0,07301032 ! UTP metabolic process GO:0046051 10 9 0,000 0,03637068 0,07295038 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,03637068 0,07289053 ! induction of positive chemotaxis GO:0050930 17 9 0,000 0,03637068 0,07283079 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,03637068 0,07277114 ! artery development GO:0060840 25 9 0,000 0,03637068 0,07271159 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,03637068 0,07265213 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,03637068 0,07259278 ! equilibrioception GO:0050957 20 9 0,000 0,03637068 0,07253352 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,03637068 0,07247436 ! chemosensory behavior GO:0007635 21 9 0,000 0,03637068 0,07241529 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,03637068 0,07235632 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,03637068 0,07229745 ! leukocyte degranulation GO:0043299 16 9 0,000 0,03637068 0,07223867 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,03637068 0,07217998 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,03637068 0,0721214 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,03637068 0,0720629 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,03637068 0,07200451 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,03637068 0,0719462 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,03637068 0,07188799 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,03637068 0,07182988 ! protein targeting to ER GO:0045047 25 9 0,000 0,03637068 0,07177186 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,03637068 0,07171393 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,03637068 0,0716561 ! glycine catabolic process GO:0006546 15 9 0,000 0,03637068 0,07159836 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,03637068 0,07154071 ! endosome organization GO:0007032 20 9 0,000 0,03637068 0,07148315 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,03637068 0,07142569 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,03637068 0,07136832 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,03637068 0,07131104 ! mannose metabolic process GO:0006013 13 9 0,000 0,03637068 0,07125386 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,03637068 0,07119676 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,03637068 0,07113976 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,03637068 0,07108285 ! receptor clustering GO:0043113 20 9 0,000 0,03637068 0,07102603 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,03637068 0,0709693 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,03637068 0,07091266 ! retinol metabolic process GO:0042572 20 9 0,000 0,03637068 0,07085611 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,03637068 0,07079965 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,03637068 0,07074328 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,03637068 0,070687 ! macrophage differentiation GO:0030225 15 9 0,000 0,03637068 0,07063081 ! oligodendrocyte development GO:0014003 11 9 0,000 0,03637068 0,07057471 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,03637068 0,0705187 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,03637068 0,07046278 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,03637068 0,07040694 ! response to amine stimulus GO:0014075 13 9 0,000 0,03637068 0,0703512 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,03637068 0,07029554 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,03637068 0,07023997 ! erythrocyte development GO:0048821 17 9 0,000 0,03637068 0,07018449 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,03637068 0,07012909 ! renal water homeostasis GO:0003091 15 9 0,000 0,03637068 0,07007379 ! postreplication repair GO:0006301 25 9 0,000 0,03637068 0,07001857 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,03637068 0,06996343 ! icosanoid secretion GO:0032309 15 9 0,000 0,03637068 0,06990839 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,03637068 0,06985343 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,03637068 0,06979855 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,03637068 0,06974377 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,03637068 0,06968907 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,03637068 0,06963445 ! sterol catabolic process GO:0016127 14 9 0,000 0,03637068 0,06957992 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,03637068 0,06952548 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,03637068 0,06947112 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,03637068 0,06941684 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,03637068 0,06936265 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 0,03637068 0,06930855 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,03637068 0,06925453 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,03637068 0,06920059 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,03637068 0,06914674 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,03637068 0,06909297 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,03637068 0,06903929 ! purine base metabolic process GO:0006144 25 9 0,000 0,03637068 0,06898568 ! pigment granule transport GO:0051904 17 9 0,000 0,03637068 0,06893216 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,03637068 0,06887873 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,03637068 0,06882538 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,03637068 0,06877211 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,03637068 0,06871892 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,03637068 0,06866581 ! mitochondrion localization GO:0051646 18 9 0,000 0,03637068 0,06861279 ! appendage development GO:0048736 151 73 1,000 0,03642247 0,06865748 GO:0060173|limb development, ! humoral immune response GO:0006959 115 73 1,000 0,03642247 0,06860454 ! regulation of caspase activity GO:0043281 136 74 1,000 0,03733543 0,07026999 ! respiratory system development GO:0060541 175 74 1,000 0,03733543 0,0702159 ! organelle localization GO:0051640 155 74 1,000 0,03733543 0,07016188 ! regulation of transcription factor activity GO:0051090 137 75 1,000 0,03825713 0,07183872 GO:0090046|regulation of transcription regulator activity, ! reproductive structure development GO:0048608 131 75 1,000 0,03825713 0,07178354 ! phosphoinositide-mediated signaling GO:0048015 141 75 1,000 0,03825713 0,07172845 ! rhythmic process GO:0048511 142 75 1,000 0,03825713 0,07167345 ! cell-matrix adhesion GO:0007160 181 76 1,000 0,0391875 0,0733602 ! regulation of actin cytoskeleton organization GO:0032956 167 76 1,000 0,0391875 0,07330403 ! regulation of endopeptidase activity GO:0052548 141 77 1,000 0,04012645 0,07500299 ! regulation of catabolic process GO:0009894 173 77 1,000 0,04012645 0,07494565 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,04032987 0,07526804 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,04032987 0,07521058 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,04032987 0,07515322 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,04032987 0,07509593 ! associative learning GO:0008306 21 10 0,000 0,04032987 0,07503874 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,04032987 0,07498163 ! phosphate transport GO:0006817 24 10 0,000 0,04032987 0,07492461 ! cell volume homeostasis GO:0006884 17 10 0,000 0,04032987 0,07486768 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,04032987 0,07481083 ! CTP metabolic process GO:0046036 11 10 0,000 0,04032987 0,07475407 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 0,04032987 0,0746974 ! GTP metabolic process GO:0046039 11 10 0,000 0,04032987 0,07464081 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,04032987 0,0745843 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,04032987 0,07452789 ! social behavior GO:0035176 29 10 0,000 0,04032987 0,07447155 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,04032987 0,07441531 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,04032987 0,07435914 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,04032987 0,07430307 ! androgen metabolic process GO:0008209 17 10 0,000 0,04032987 0,07424707 ! phospholipid efflux GO:0033700 19 10 0,000 0,04032987 0,07419116 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,04032987 0,07413534 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,04032987 0,0740796 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,04032987 0,07402394 ! lung alveolus development GO:0048286 26 10 0,000 0,04032987 0,07396837 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,04032987 0,07391288 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,04032987 0,07385747 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,04032987 0,07380215 ! endoderm development GO:0007492 18 10 0,000 0,04032987 0,07374691 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,04032987 0,07369175 ! arginine catabolic process GO:0006527 17 10 0,000 0,04032987 0,07363667 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,04032987 0,07358168 ! proline metabolic process GO:0006560 13 10 0,000 0,04032987 0,07352677 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,04032987 0,07347194 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 0,04032987 0,07341719 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,04032987 0,07336252 ! V(D)J recombination GO:0033151 34 10 0,000 0,04032987 0,07330794 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,04032987 0,07325343 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,04032987 0,07319901 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,04032987 0,07314467 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,04032987 0,0730904 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,04032987 0,07303622 ! multicellular organism growth GO:0035264 19 10 0,000 0,04032987 0,07298212 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,04032987 0,0729281 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,04032987 0,07287416 ! ruffle organization GO:0031529 17 10 0,000 0,04032987 0,0728203 ! epithelial cell development GO:0002064 21 10 0,000 0,04032987 0,07276652 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,04032987 0,07271282 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,04032987 0,07265919 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,04032987 0,07260565 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,04032987 0,07255218 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,04032987 0,0724988 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,04032987 0,07244549 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 13 10 0,000 0,04032987 0,07239226 ! regulation of bone resorption GO:0045124 25 10 0,000 0,04032987 0,07233911 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,04032987 0,07228604 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,04032987 0,07223304 ! segment specification GO:0007379 15 10 0,000 0,04032987 0,07218012 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,04032987 0,07212728 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 0,000 0,04032987 0,07207452 ! blastoderm segmentation GO:0007350 19 10 0,000 0,04032987 0,07202183 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,04032987 0,07196922 ! response to dsRNA GO:0043331 23 10 0,000 0,04032987 0,07191669 ! DNA ligation GO:0006266 18 10 0,000 0,04032987 0,07186423 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,04032987 0,07181186 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,04032987 0,07175955 ! melanosome localization GO:0032400 16 10 0,000 0,04032987 0,07170733 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,04032987 0,07165518 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,04032987 0,0716031 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,04032987 0,0715511 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,04032987 0,07149918 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,04032987 0,07144733 ! induction of an organ GO:0001759 17 10 0,000 0,04032987 0,07139556 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,04032987 0,07134386 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,04032987 0,07129223 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,04032987 0,07124068 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,04032987 0,07118921 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,04032987 0,07113781 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,04032987 0,07108648 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,04032987 0,07103523 ! salivary gland development GO:0007431 28 10 0,000 0,04032987 0,07098405 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,04032987 0,07093295 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,04032987 0,07088192 ! midbrain development GO:0030901 14 10 0,000 0,04032987 0,07083096 ! musculoskeletal movement GO:0050881 16 10 0,000 0,04032987 0,07078008 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,04032987 0,07072926 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,04032987 0,07067853 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,04032987 0,07062786 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,04032987 0,07057727 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,04032987 0,07052675 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,04032987 0,0704763 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,04032987 0,07042592 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,04032987 0,07037562 ! detection of calcium ion GO:0005513 24 10 0,000 0,04032987 0,07032539 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,04032987 0,07027523 ! blastocyst formation GO:0001825 18 10 0,000 0,04032987 0,07022514 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,04032987 0,07017512 ! cerebellar cortex development GO:0021695 16 10 0,000 0,04032987 0,07012517 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,04032987 0,0700753 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,04032987 0,07002549 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,04032987 0,06997576 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,04032987 0,06992609 ! positive regulation of lymphocyte activation GO:0051251 142 78 1,000 0,04107389 0,0711656 ! blood coagulation GO:0007596 151 79 1,000 0,04202973 0,07277012 GO:0050817|coagulation, ! regulation of actin filament-based process GO:0032970 170 79 1,000 0,04202973 0,07271858 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 1,000 0,04202973 0,07266712 ! regulation of synaptic transmission GO:0050804 159 79 1,000 0,04202973 0,07261572 ! development of primary sexual characteristics GO:0045137 143 80 1,000 0,0429939 0,07422905 ! meiosis GO:0007126 143 81 1,000 0,04396631 0,07585431 GO:0051327|M phase of meiotic cell cycle, ! muscle cell differentiation GO:0042692 178 81 1,000 0,04396631 0,07580077 ! positive regulation of phosphorylation GO:0042327 149 81 1,000 0,04396631 0,07574732 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 1,000 0,04396631 0,07569394 ! respiratory burst GO:0045730 17 11 0,000 0,0442729 0,0761681 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,0442729 0,0761145 ! neuron fate specification GO:0048665 18 11 0,000 0,0442729 0,07606097 ! telencephalon cell migration GO:0022029 23 11 0,000 0,0442729 0,07600752 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,0442729 0,07595415 ! thyroid gland development GO:0030878 26 11 0,000 0,0442729 0,07590084 ! synapsis GO:0007129 14 11 0,000 0,0442729 0,07584762 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,0442729 0,07579447 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,0442729 0,07574139 ! response to pain GO:0048265 27 11 0,000 0,0442729 0,07568839 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,0442729 0,07563546 ! keratinocyte proliferation GO:0043616 19 11 0,000 0,0442729 0,0755826 ! blood vessel remodeling GO:0001974 30 11 0,000 0,0442729 0,07552982 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 0,000 0,0442729 0,07547711 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 23 11 0,000 0,0442729 0,07542448 ! bone resorption GO:0045453 16 11 0,000 0,0442729 0,07537192 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,0442729 0,07531943 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,0442729 0,07526702 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,0442729 0,07521468 ! melanocyte differentiation GO:0030318 20 11 0,000 0,0442729 0,07516241 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,0442729 0,07511021 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,0442729 0,07505809 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,0442729 0,07500604 ! UV protection GO:0009650 20 11 0,000 0,0442729 0,07495406 ! chondrocyte differentiation GO:0002062 27 11 0,000 0,0442729 0,07490215 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,0442729 0,07485031 ! macroautophagy GO:0016236 19 11 0,000 0,0442729 0,07479855 ! temperature homeostasis GO:0001659 18 11 0,000 0,0442729 0,07474686 ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,0442729 0,07469524 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,0442729 0,07464369 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,0442729 0,07459221 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 0,0442729 0,0745408 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,0442729 0,07448946 ! regulation of organ growth GO:0046620 14 11 0,000 0,0442729 0,0744382 ! pigment granule localization GO:0051875 20 11 0,000 0,0442729 0,074387 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,0442729 0,07433588 ! vasoconstriction GO:0042310 20 11 0,000 0,0442729 0,07428482 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,0442729 0,07423384 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,0442729 0,07418292 ! embryonic axis specification GO:0000578 19 11 0,000 0,0442729 0,07413208 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,0442729 0,0740813 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,0442729 0,0740306 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,0442729 0,07397996 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,0442729 0,07392939 GO:0006809|nitric oxide biosynthetic process, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,0442729 0,0738789 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,0442729 0,07382847 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,0442729 0,07377811 ! prophase GO:0051324 17 11 0,000 0,0442729 0,07372781 ! neuroblast proliferation GO:0007405 25 11 0,000 0,0442729 0,07367759 ! nucleosome positioning GO:0016584 15 11 0,000 0,0442729 0,07362744 ! regulation of isotype switching GO:0045191 24 11 0,000 0,0442729 0,07357735 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,0442729 0,07352733 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,0442729 0,07347738 ! acid secretion GO:0046717 20 11 0,000 0,0442729 0,0734275 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,0442729 0,07337768 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,0442729 0,07332793 ! positive regulation of leukocyte migration GO:0002687 28 11 0,000 0,0442729 0,07327825 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,0442729 0,07322864 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,0442729 0,0731791 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,0442729 0,07312962 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! cholesterol efflux GO:0033344 21 11 0,000 0,0442729 0,0730802 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,0442729 0,07303086 ! negative regulation of glucose import GO:0046325 18 11 0,000 0,0442729 0,07298158 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 26 11 0,000 0,0442729 0,07293237 ! embryonic gut development GO:0048566 19 11 0,000 0,0442729 0,07288322 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,0442729 0,07283414 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,0442729 0,07278513 ! activation of innate immune response GO:0002218 16 11 0,000 0,0442729 0,07273618 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,0442729 0,0726873 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,0442729 0,07263848 ! lysogeny GO:0030069 22 11 0,000 0,0442729 0,07258973 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,0442729 0,07254105 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,0442729 0,07249243 ! sequestering of metal ion GO:0051238 15 11 0,000 0,0442729 0,07244387 ! nucleus localization GO:0051647 22 11 0,000 0,0442729 0,07239538 ! regulation of peptidase activity GO:0052547 150 82 1,000 0,04494688 0,07344831 ! cell-substrate adhesion GO:0031589 189 82 1,000 0,04494688 0,07339921 ! protein import into nucleus GO:0006606 174 82 1,000 0,04494688 0,07335018 ! meiotic cell cycle GO:0051321 144 82 1,000 0,04494688 0,07330122 ! cellular lipid catabolic process GO:0044242 150 83 1,000 0,04593552 0,07486356 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 1,000 0,04593552 0,07481365 GO:0045937|positive regulation of phosphate metabolic process, ! nuclear import GO:0051170 177 83 1,000 0,04593552 0,07476381 ! regulation of ligase activity GO:0051340 147 84 1,000 0,04693215 0,07633505 ! hemostasis GO:0007599 165 85 1,000 0,0479367 0,07791707 ! regulation of neuron differentiation GO:0045664 187 85 1,000 0,0479367 0,07786526 ! regulation of transmission of nerve impulse GO:0051969 167 85 1,000 0,0479367 0,07781353 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,04819985 0,07818873 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,04819985 0,07813685 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,04819985 0,07808503 ! regulation of positive chemotaxis GO:0050926 22 12 0,000 0,04819985 0,07803329 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,04819985 0,07798161 ! protein complex disassembly GO:0043241 28 12 0,000 0,04819985 0,07793 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,04819985 0,07787846 ! regulation of cell projection assembly GO:0060491 33 12 0,000 0,04819985 0,07782699 ! hippocampus development GO:0021766 29 12 0,000 0,04819985 0,07777558 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 0,000 0,04819985 0,07772424 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,04819985 0,07767298 ! T cell proliferation GO:0042098 32 12 0,000 0,04819985 0,07762177 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,04819985 0,07757064 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,04819985 0,07751957 ! ventral spinal cord development GO:0021517 25 12 0,000 0,04819985 0,07746857 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,04819985 0,07741764 ! drug transport GO:0015893 16 12 0,000 0,04819985 0,07736677 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,04819985 0,07731598 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,04819985 0,07726524 ! polyamine metabolic process GO:0006595 18 12 0,000 0,04819985 0,07721458 ! mitotic spindle organization GO:0007052 23 12 0,000 0,04819985 0,07716398 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,04819985 0,07711345 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,04819985 0,07706298 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,04819985 0,07701258 ! lipid digestion GO:0044241 21 12 0,000 0,04819985 0,07696224 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,04819985 0,07691197 ! entry into host cell GO:0030260 34 12 0,000 0,04819985 0,07686177 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,04819985 0,07681163 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,04819985 0,07676156 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,04819985 0,07671155 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,04819985 0,07666161 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,04819985 0,07661173 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,04819985 0,07656192 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,04819985 0,07651217 ! snRNA metabolic process GO:0016073 30 12 0,000 0,04819985 0,07646249 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,04819985 0,07641287 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,04819985 0,07636331 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,04819985 0,07631382 ! cranial nerve development GO:0021545 23 12 0,000 0,04819985 0,0762644 ! fucose catabolic process GO:0019317 25 12 0,000 0,04819985 0,07621504 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,04819985 0,07616574 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,04819985 0,0761165 ! autonomic nervous system development GO:0048483 24 12 0,000 0,04819985 0,07606733 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 0,04819985 0,07601823 ! zymogen activation GO:0031638 18 12 0,000 0,04819985 0,07596918 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,04819985 0,0759202 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,04819985 0,07587128 ! regulation of leukocyte migration GO:0002685 29 12 0,000 0,04819985 0,07582243 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,04819985 0,07577364 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,04819985 0,07572491 ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 0,000 0,04819985 0,07567624 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,04819985 0,07562764 ! defense response to fungus GO:0050832 15 12 0,000 0,04819985 0,0755791 ! developmental induction GO:0031128 22 12 0,000 0,04819985 0,07553062 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 21 12 0,000 0,04819985 0,0754822 ! lamellipodium assembly GO:0030032 24 12 0,000 0,04819985 0,07543384 ! response to cold GO:0009409 17 12 0,000 0,04819985 0,07538555 ! establishment of cell polarity GO:0030010 21 12 0,000 0,04819985 0,07533732 ! regulation of synapse organization GO:0050807 18 12 0,000 0,04819985 0,07528915 ! positive regulation of cell activation GO:0050867 161 86 1,000 0,04894908 0,0764106 GO:0002696|positive regulation of leukocyte activation, ! cellular respiration GO:0045333 143 88 1,000 0,050997 0,07955663 ! one-carbon metabolic process GO:0006730 167 88 1,000 0,050997 0,07950586 ! regulation of DNA binding GO:0051101 167 89 1,000 0,05203239 0,08106833 ! protein localization in nucleus GO:0034504 192 89 1,000 0,05203239 0,08101666 ! regulation of neurological system process GO:0031644 175 89 1,000 0,05203239 0,08096505 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,05211077 0,0810354 ! cGMP metabolic process GO:0046068 18 13 0,000 0,05211077 0,08098385 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,05211077 0,08093236 ! regulation of chemokine production GO:0032642 18 13 0,000 0,05211077 0,08088095 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,05211077 0,08082959 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,05211077 0,08077831 ! peroxisomal transport GO:0043574 28 13 0,000 0,05211077 0,08072708 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,05211077 0,08067592 ! cartilage condensation GO:0001502 22 13 0,000 0,05211077 0,08062483 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,05211077 0,0805738 ! organelle fusion GO:0048284 36 13 0,000 0,05211077 0,08052284 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,05211077 0,08047194 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,05211077 0,0804211 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,05211077 0,08037033 ! endocrine pancreas development GO:0031018 25 13 0,000 0,05211077 0,08031963 ! positive regulation of cell growth GO:0030307 24 13 0,000 0,05211077 0,08026898 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,05211077 0,08021841 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,05211077 0,08016789 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,05211077 0,08011744 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,05211077 0,08006705 ! methionine metabolic process GO:0006555 31 13 0,000 0,05211077 0,08001672 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,05211077 0,07996646 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,05211077 0,07991626 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,05211077 0,07986613 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,05211077 0,07981606 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! cytokine metabolic process GO:0042107 24 13 0,000 0,05211077 0,07976605 ! cellular carbohydrate catabolic process GO:0044275 17 13 0,000 0,05211077 0,0797161 ! exocrine system development GO:0035272 34 13 0,000 0,05211077 0,07966621 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,05211077 0,07961639 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 0,05211077 0,07956663 ! L-glutamate transport GO:0015813 30 13 0,000 0,05211077 0,07951693 GO:0015800|acidic amino acid transport, ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,05211077 0,0794673 ! protein homotetramerization GO:0051289 24 13 0,000 0,05211077 0,07941772 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,05211077 0,07936821 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,05211077 0,07931876 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,05211077 0,07926937 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,05211077 0,07922004 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,05211077 0,07917078 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,05211077 0,07912157 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,05211077 0,07907243 ! histone methylation GO:0016571 29 13 0,000 0,05211077 0,07902335 ! chromatin silencing GO:0006342 29 13 0,000 0,05211077 0,07897432 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,05211077 0,07892536 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 0,05211077 0,07887646 ! regulation of epidermis development GO:0045682 19 13 0,000 0,05211077 0,07882762 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,05211077 0,07877884 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,05211077 0,07873012 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,05211077 0,07868146 ! regulation of mRNA stability GO:0043488 32 13 0,000 0,05211077 0,07863287 ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,05211077 0,07858433 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,05211077 0,07853585 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,05211077 0,07848743 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,05211077 0,07843907 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,05211077 0,07839077 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,05211077 0,07834253 ! insulin secretion GO:0030073 24 13 0,000 0,05211077 0,07829435 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,05211077 0,07824623 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 0,05211077 0,07819816 ! acrosome reaction GO:0007340 19 13 0,000 0,05211077 0,07815016 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,05211077 0,07810221 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,05211077 0,07805433 ! rRNA transcription GO:0009303 28 14 0,000 0,05600573 0,08383701 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,05600573 0,08378567 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 0,05600573 0,08373439 ! water transport GO:0006833 21 14 0,000 0,05600573 0,08368318 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,05600573 0,08363203 ! non-recombinational repair GO:0000726 29 14 0,000 0,05600573 0,08358094 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,05600573 0,08352991 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,05600573 0,08347895 ! RNA polyadenylation GO:0043631 32 14 0,000 0,05600573 0,08342805 ! lipid localization GO:0010876 32 14 0,000 0,05600573 0,08337721 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 0,05600573 0,08332643 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 0,000 0,05600573 0,08327571 ! regulated secretory pathway GO:0045055 24 14 0,000 0,05600573 0,08322506 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,05600573 0,08317447 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,05600573 0,08312393 ! arginine metabolic process GO:0006525 21 14 0,000 0,05600573 0,08307346 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,05600573 0,08302306 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,05600573 0,08297271 ! regulation of heart rate GO:0002027 25 14 0,000 0,05600573 0,08292242 ! organic alcohol transport GO:0015850 29 14 0,000 0,05600573 0,0828722 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,05600573 0,08282203 ! embryo implantation GO:0007566 30 14 0,000 0,05600573 0,08277193 ! neutral amino acid transport GO:0015804 28 14 0,000 0,05600573 0,08272188 ! bone mineralization GO:0030282 18 14 0,000 0,05600573 0,0826719 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,05600573 0,08262198 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,05600573 0,08257212 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,05600573 0,08252231 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,05600573 0,08247257 ! ribosome assembly GO:0042255 18 14 0,000 0,05600573 0,08242289 ! cerebellum development GO:0021549 23 14 0,000 0,05600573 0,08237327 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,05600573 0,0823237 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,05600573 0,0822742 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,05600573 0,08222476 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,05600573 0,08217537 ! NADP metabolic process GO:0006739 24 14 0,000 0,05600573 0,08212605 ! oxygen transport GO:0015671 22 14 0,000 0,05600573 0,08207678 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,05600573 0,08202758 ! male genitalia development GO:0030539 26 14 0,000 0,05600573 0,08197843 ! regulation of RNA stability GO:0043487 33 14 0,000 0,05600573 0,08192934 ! regulation of axon extension GO:0030516 43 14 0,000 0,05600573 0,08188031 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,05600573 0,08183134 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 0,05600573 0,08178242 ! regulation of cell morphogenesis GO:0022604 243 93 1,000 0,0562483 0,08208757 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 1,000 0,0562483 0,08203857 GO:0010498|proteasomal protein catabolic process, ! female pregnancy GO:0007565 166 94 1,000 0,05732048 0,08355246 ! carbohydrate biosynthetic process GO:0016051 158 94 1,000 0,05732048 0,08350264 ! cofactor biosynthetic process GO:0051188 161 95 1,000 0,05839978 0,08502423 ! negative regulation of multicellular organismal process GO:0051241 174 95 1,000 0,05839978 0,08497359 ! sex differentiation GO:0007548 171 96 1,000 0,05948613 0,08650275 ! response to protein stimulus GO:0051789 158 96 1,000 0,05948613 0,08645129 ! regulation of T cell activation GO:0050863 175 96 1,000 0,05948613 0,0863999 ! lactation GO:0007595 30 15 0,000 0,05988479 0,08692724 ! reproductive cellular process GO:0048610 22 15 0,000 0,05988479 0,08687562 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,05988479 0,08682407 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,05988479 0,08677257 ! superoxide anion generation GO:0042554 22 15 0,000 0,05988479 0,08672113 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,05988479 0,08666976 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,05988479 0,08661844 ! copper ion transport GO:0006825 22 15 0,000 0,05988479 0,08656719 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,05988479 0,086516 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,05988479 0,08646486 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,05988479 0,08641379 ! sulfate transport GO:0008272 27 15 0,000 0,05988479 0,08636278 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,05988479 0,08631183 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,05988479 0,08626094 ! regulation of mRNA processing GO:0050684 26 15 0,000 0,05988479 0,08621011 ! response to hexose stimulus GO:0009746 25 15 0,000 0,05988479 0,08615934 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,05988479 0,08610862 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,05988479 0,08605797 ! vesicle coating GO:0006901 38 15 0,000 0,05988479 0,08600738 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 0,05988479 0,08595685 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 0,05988479 0,08590637 ! regulation of exocytosis GO:0017157 26 15 0,000 0,05988479 0,08585596 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,05988479 0,0858056 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,05988479 0,08575531 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,05988479 0,08570507 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,05988479 0,08565489 ! regulation of vasodilation GO:0042312 27 15 0,000 0,05988479 0,08560477 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,05988479 0,08555471 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,05988479 0,08550471 ! water homeostasis GO:0030104 28 15 0,000 0,05988479 0,08545476 ! cofactor transport GO:0051181 30 15 0,000 0,05988479 0,08540488 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,05988479 0,08535505 ! muscle maintenance GO:0046716 26 15 0,000 0,05988479 0,08530528 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,05988479 0,08525557 ! intestinal absorption GO:0050892 31 15 0,000 0,05988479 0,08520591 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,05988479 0,08515632 ! heme biosynthetic process GO:0006783 33 15 0,000 0,05988479 0,08510678 ! cell killing GO:0001906 32 15 0,000 0,05988479 0,0850573 ! epithelial to mesenchymal transition GO:0001837 30 15 0,000 0,05988479 0,08500787 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,05988479 0,08495851 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,05988479 0,0849092 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,05988479 0,08485995 ! actin filament polymerization GO:0030041 27 15 0,000 0,05988479 0,08481075 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,05988479 0,08476162 ! biogenic amine metabolic process GO:0006576 162 97 1,000 0,06057946 0,08569521 ! transcription initiation GO:0006352 171 97 1,000 0,06057946 0,08564562 ! forebrain development GO:0030900 210 98 1,000 0,0616797 0,08715066 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,06374803 0,09002106 ! positive regulation of cell size GO:0045793 29 16 0,000 0,06374803 0,08996905 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,06374803 0,08991711 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,06374803 0,08986522 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,06374803 0,0898134 ! bone remodeling GO:0046849 28 16 0,000 0,06374803 0,08976163 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 0,000 0,06374803 0,08970993 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,06374803 0,08965828 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,06374803 0,08960669 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,06374803 0,08955516 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,06374803 0,0895037 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,06374803 0,08945229 ! startle response GO:0001964 28 16 0,000 0,06374803 0,08940094 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,06374803 0,08934964 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,06374803 0,08929841 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,06374803 0,08924724 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,06374803 0,08919612 ! protein polyubiquitination GO:0000209 41 16 0,000 0,06374803 0,08914507 ! glutamate metabolic process GO:0006536 25 16 0,000 0,06374803 0,08909407 ! pituitary gland development GO:0021983 30 16 0,000 0,06374803 0,08904313 ! response to osmotic stress GO:0006970 27 16 0,000 0,06374803 0,08899225 ! lysosomal transport GO:0007041 31 16 0,000 0,06374803 0,08894142 ! fructose metabolic process GO:0006000 25 16 0,000 0,06374803 0,08889066 ! L-amino acid transport GO:0015807 33 16 0,000 0,06374803 0,08883995 ! stem cell development GO:0048864 46 16 0,000 0,06374803 0,0887893 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,06374803 0,08873871 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,06374803 0,08868817 ! intermediate filament-based process GO:0045103 36 16 0,000 0,06374803 0,0886377 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,06374803 0,08858728 ! negative regulation of immune response GO:0050777 38 16 0,000 0,06374803 0,08853691 ! axon cargo transport GO:0008088 46 16 0,000 0,06374803 0,08848661 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,06374803 0,08843636 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,06374803 0,08838617 ! positive regulation of protein import into nucleus GO:0042307 34 16 0,000 0,06374803 0,08833604 ! DNA replication initiation GO:0006270 28 16 0,000 0,06374803 0,08828596 ! neuron recognition GO:0008038 40 16 0,000 0,06374803 0,08823594 ! mRNA splice site selection GO:0006376 44 16 0,000 0,06374803 0,08818597 ! tissue regeneration GO:0042246 27 16 0,000 0,06374803 0,08813607 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,06374803 0,08808622 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,06374803 0,08803642 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,06374803 0,08798668 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,06374803 0,087937 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,06374803 0,08788738 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,06374803 0,08783781 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,06374803 0,08778829 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,06374803 0,08773883 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,06374803 0,08768943 ! peptide hormone processing GO:0016486 27 16 0,000 0,06374803 0,08764008 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,06759549 0,09287727 ! signal complex assembly GO:0007172 47 17 0,000 0,06759549 0,09282507 ! filopodium assembly GO:0046847 42 17 0,000 0,06759549 0,09277292 ! endothelial cell migration GO:0043542 31 17 0,000 0,06759549 0,09272083 ! gene silencing by RNA GO:0031047 38 17 0,000 0,06759549 0,09266879 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,06759549 0,09261682 ! glial cell development GO:0021782 28 17 0,000 0,06759549 0,09256491 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,06759549 0,09251305 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,06759549 0,09246125 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,06759549 0,09240951 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 0,000 0,06759549 0,09235783 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,06759549 0,0923062 ! myoblast differentiation GO:0045445 50 17 0,000 0,06759549 0,09225463 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,06759549 0,09220312 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 0,000 0,06759549 0,09215167 ! regulation of survival gene product expression GO:0045884 38 17 0,000 0,06759549 0,09210027 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,06759549 0,09204894 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,06759549 0,09199766 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,06759549 0,09194643 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,06759549 0,09189526 ! NAD metabolic process GO:0019674 33 17 0,000 0,06759549 0,09184416 ! membrane budding GO:0006900 42 17 0,000 0,06759549 0,0917931 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,06759549 0,09174211 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,06759549 0,09169117 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,06759549 0,09164028 ! genitalia development GO:0048806 32 17 0,000 0,06759549 0,09158946 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,06759549 0,09153869 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 0,000 0,06759549 0,09148797 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,06759549 0,09143732 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,06759549 0,09138671 ! neutrophil chemotaxis GO:0030593 29 17 0,000 0,06759549 0,09133617 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,06759549 0,09128568 ! steroid catabolic process GO:0006706 34 17 0,000 0,06759549 0,09123524 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,06759549 0,09118487 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,06759549 0,09113454 ! gas transport GO:0015669 26 17 0,000 0,06759549 0,09108428 ! organic cation transport GO:0015695 32 17 0,000 0,06759549 0,09103406 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,06759549 0,09098391 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,06759549 0,09093381 ! positive regulation of protein complex assembly GO:0031334 34 18 0,000 0,07142726 0,09603566 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,07142726 0,09598283 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,07142726 0,09593007 ! limbic system development GO:0021761 40 18 0,000 0,07142726 0,09587736 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,07142726 0,09582471 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,07142726 0,09577211 ! adult walking behavior GO:0007628 36 18 0,000 0,07142726 0,09571958 ! patterning of blood vessels GO:0001569 43 18 0,000 0,07142726 0,0956671 ! heart looping GO:0001947 34 18 0,000 0,07142726 0,09561468 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,07142726 0,09556232 ! centrosome cycle GO:0007098 26 18 0,000 0,07142726 0,09551001 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,07142726 0,09545776 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,07142726 0,09540557 ! glycine metabolic process GO:0006544 30 18 0,000 0,07142726 0,09535344 ! glutamine metabolic process GO:0006541 29 18 0,000 0,07142726 0,09530136 ! response to retinoic acid GO:0032526 31 18 0,000 0,07142726 0,09524934 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,07142726 0,09519738 ! DNA integration GO:0015074 32 18 0,000 0,07142726 0,09514547 ! negative regulation of protein catabolic process GO:0042177 42 18 0,000 0,07142726 0,09509362 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,07142726 0,09504182 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,07142726 0,09499009 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,07142726 0,09493841 ! neural crest cell migration GO:0001755 41 18 0,000 0,07142726 0,09488678 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,07142726 0,09483521 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,07142726 0,0947837 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,07142726 0,09473224 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,07142726 0,09468084 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,07142726 0,0946295 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,07142726 0,09457821 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,07142726 0,09452697 ! detection of bacterium GO:0016045 22 18 0,000 0,07142726 0,09447579 ! nerve development GO:0021675 34 18 0,000 0,07142726 0,09442467 ! microspike assembly GO:0030035 46 18 0,000 0,07142726 0,0943736 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,07142726 0,09432259 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,07524338 0,09930825 ! positive regulation of translation GO:0045727 31 19 0,000 0,07524338 0,09925463 ! negative regulation of defense response GO:0031348 27 19 0,000 0,07524338 0,09920107 ! G1 phase of mitotic cell cycle GO:0000080 39 19 0,000 0,07524338 0,09914756 ! neuron maturation GO:0042551 46 19 0,000 0,07524338 0,09909411 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,07524338 0,09904072 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,07524338 0,09898739 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,07524338 0,09893411 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,07524338 0,09888089 ! inositol metabolic process GO:0006020 33 19 0,000 0,07524338 0,09882773 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,07524338 0,09877463 ! memory GO:0007613 34 19 0,000 0,07524338 0,09872158 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,07524338 0,09866859 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,07524338 0,09861565 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,07524338 0,09856278 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,07524338 0,09850996 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 0,000 0,07524338 0,09845719 ! cerebral cortex development GO:0021987 40 19 0,000 0,07524338 0,09840449 ! pigmentation during development GO:0048066 42 19 0,000 0,07524338 0,09835184 ! response to vitamin A GO:0033189 32 19 0,000 0,07524338 0,09829924 ! heme metabolic process GO:0042168 40 19 0,000 0,07524338 0,0982467 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,07524338 0,09819422 ! regulation of endothelial cell migration GO:0010594 45 19 0,000 0,07524338 0,09814179 ! response to fungus GO:0009620 26 19 0,000 0,07524338 0,09808942 ! peptide cross-linking GO:0018149 39 19 0,000 0,07524338 0,09803711 ! protein export from nucleus GO:0006611 40 19 0,000 0,07524338 0,09798485 ! heart process GO:0003015 32 19 0,000 0,07524338 0,09793265 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,07524338 0,0978805 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,07524338 0,09782841 ! visual learning GO:0008542 38 19 0,000 0,07524338 0,09777637 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,07524338 0,09772439 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,07524338 0,09767247 ! vitamin transport GO:0051180 31 19 0,000 0,07524338 0,09762059 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,07524338 0,09756878 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,07524338 0,09751702 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,07524338 0,09746531 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,07524338 0,09741366 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,07524338 0,09736207 ! cilium assembly GO:0042384 38 19 0,000 0,07524338 0,09731052 ! peptide hormone secretion GO:0030072 32 19 0,000 0,07524338 0,09725904 ! protein secretion GO:0009306 45 20 0,000 0,07904393 0,10211757 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,07904393 0,10206359 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,07904393 0,10200968 ! positive regulation of ossification GO:0045778 50 20 0,000 0,07904393 0,10195582 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,07904393 0,10190202 ! phosphoinositide phosphorylation GO:0046854 40 20 0,000 0,07904393 0,10184827 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,07904393 0,10179458 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,07904393 0,10174095 ! response to vitamin GO:0033273 36 20 0,000 0,07904393 0,10168737 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,07904393 0,10163385 ! bile acid metabolic process GO:0008206 34 20 0,000 0,07904393 0,10158039 ! retinoid metabolic process GO:0001523 34 20 0,000 0,07904393 0,10152698 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 40 20 0,000 0,07904393 0,10147363 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,07904393 0,10142034 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,07904393 0,1013671 GO:0032392|DNA geometric change, ! cellular response to unfolded protein GO:0034620 35 20 0,000 0,07904393 0,10131391 GO:0030968|endoplasmic reticulum unfolded protein response, ! actin filament bundle formation GO:0051017 47 20 0,000 0,07904393 0,10126079 ! body fluid secretion GO:0007589 33 20 0,000 0,07904393 0,10120771 ! peptide secretion GO:0002790 38 20 0,000 0,07904393 0,1011547 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,07904393 0,10110174 ! regulation of fatty acid metabolic process GO:0019217 45 20 0,000 0,07904393 0,10104883 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,07904393 0,10099598 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,07904393 0,10094319 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,07904393 0,10089045 ! cell-cell junction organization GO:0045216 43 20 0,000 0,07904393 0,10083776 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,07904393 0,10078514 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,07904393 0,10073256 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,07904393 0,10068004 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,07904393 0,10062758 ! regulation of glucose import GO:0046324 30 20 0,000 0,07904393 0,10057517 GO:0010827|regulation of glucose transport, ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,07904393 0,10052281 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,07904393 0,10047051 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,07904393 0,10041826 ! regulation of cell killing GO:0031341 46 21 0,000 0,08282896 0,10517212 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,08282896 0,10511749 ! hormone secretion GO:0046879 39 21 0,000 0,08282896 0,10506291 ! lipid phosphorylation GO:0046834 43 21 0,000 0,08282896 0,10500839 ! cAMP metabolic process GO:0046058 41 21 0,000 0,08282896 0,10495392 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,08282896 0,10489951 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,08282896 0,10484516 ! smooth muscle contraction GO:0006939 48 21 0,000 0,08282896 0,10479086 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,08282896 0,10473662 ! cell structure disassembly during apoptosis GO:0006921 32 21 0,000 0,08282896 0,10468244 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,08282896 0,10462831 ! plasma membrane fusion GO:0045026 33 21 0,000 0,08282896 0,10457424 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,08282896 0,10452023 ! regulation of vasoconstriction GO:0019229 40 21 0,000 0,08282896 0,10446627 ! sensory perception of pain GO:0019233 33 21 0,000 0,08282896 0,10441236 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,08282896 0,10435851 ! diencephalon development GO:0021536 36 21 0,000 0,08282896 0,10430472 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,08282896 0,10425098 ! negative regulation of intracellular transport GO:0032387 44 21 0,000 0,08282896 0,1041973 ! positive regulation of inflammatory response GO:0050729 41 21 0,000 0,08282896 0,10414367 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,08282896 0,1040901 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 0,08282896 0,10403659 ! collagen catabolic process GO:0030574 29 21 0,000 0,08282896 0,10398312 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,08282896 0,10392972 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,08282896 0,10387637 ! sperm-egg recognition GO:0035036 23 21 0,000 0,08282896 0,10382307 ! actin filament-based movement GO:0030048 47 21 0,000 0,08282896 0,10376983 ! positive regulation of protein catabolic process GO:0045732 44 22 0,000 0,08659855 0,10843683 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,08659855 0,10838128 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,08659855 0,10832578 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,08659855 0,10827035 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,08659855 0,10821496 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,08659855 0,10815964 ! microtubule-based transport GO:0010970 59 22 0,000 0,08659855 0,10810437 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,08659855 0,10804916 ! inactivation of MAPK activity GO:0000188 45 22 0,000 0,08659855 0,107994 ! vacuolar transport GO:0007034 41 22 0,000 0,08659855 0,10793891 ! central nervous system neuron development GO:0021954 47 22 0,000 0,08659855 0,10788386 ! fucose metabolic process GO:0006004 44 22 0,000 0,08659855 0,10782888 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,08659855 0,10777395 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,08659855 0,10771907 ! apoptotic nuclear changes GO:0030262 34 22 0,000 0,08659855 0,10766425 ! stem cell differentiation GO:0048863 57 22 0,000 0,08659855 0,10760949 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,08659855 0,10755478 ! cytolysis GO:0019835 27 22 0,000 0,08659855 0,10750013 ! vasodilation GO:0042311 40 22 0,000 0,08659855 0,10744553 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,08659855 0,10739099 ! positive regulation of locomotion GO:0040017 44 22 0,000 0,08659855 0,10733651 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! detection of chemical stimulus GO:0009593 42 22 0,000 0,08659855 0,10728208 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,08659855 0,1072277 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,08659855 0,10717338 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,08659855 0,10711912 ! sarcomere organization GO:0045214 32 22 0,000 0,08659855 0,10706491 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,08659855 0,10701075 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,08659855 0,10695665 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,08659855 0,10690261 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,08659855 0,10684861 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,08659855 0,10679468 ! protein stabilization GO:0050821 41 22 0,000 0,08659855 0,1067408 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,09035275 0,11131203 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,09035275 0,11125593 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,09035275 0,11119988 ! glycerol metabolic process GO:0006071 40 23 0,000 0,09035275 0,11114389 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,09035275 0,11108795 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of chemotaxis GO:0050920 45 23 0,000 0,09035275 0,11103207 ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,09035275 0,11097625 ! axis specification GO:0009798 43 23 0,000 0,09035275 0,11092048 ! visual behavior GO:0007632 46 23 0,000 0,09035275 0,11086477 ! regulation of DNA recombination GO:0000018 51 23 0,000 0,09035275 0,11080912 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,09035275 0,11075352 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,09035275 0,11069797 ! peroxisome organization GO:0007031 43 23 0,000 0,09035275 0,11064249 ! lysosome organization GO:0007040 47 23 0,000 0,09035275 0,11058705 ! vesicle targeting GO:0006903 49 23 0,000 0,09035275 0,11053168 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,09035275 0,11047636 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,09035275 0,11042109 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,09035275 0,11036588 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,09035275 0,11031073 ! fatty acid transport GO:0015908 47 23 0,000 0,09035275 0,11025562 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,09035275 0,11020058 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,09035275 0,11014559 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,09035275 0,11009065 ! hormone transport GO:0009914 41 23 0,000 0,09035275 0,11003577 ! cell-cell recognition GO:0009988 28 23 0,000 0,09035275 0,10998095 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,09035275 0,10992618 ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,09035275 0,10987146 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,09409162 0,11436111 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,09409162 0,11430424 GO:0016444|somatic cell DNA recombination, ! DNA catabolic process, endonucleolytic GO:0000737 38 24 0,000 0,09409162 0,11424743 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,09409162 0,11419067 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,09409162 0,11413398 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,09409162 0,11407733 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,09409162 0,11402075 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 0,09409162 0,11396422 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,09409162 0,11390774 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,09409162 0,11385133 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,09409162 0,11379496 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,09409162 0,11373866 GO:0042278|purine nucleoside metabolic process, ! positive regulation of cytoskeleton organization GO:0051495 52 24 0,000 0,09409162 0,11368241 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,09409162 0,11362621 GO:0051693|actin filament capping, ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,09409162 0,11357007 GO:0002708|positive regulation of lymphocyte mediated immunity, ! leukotriene metabolic process GO:0006691 47 24 0,000 0,09409162 0,11351399 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,09409162 0,11345796 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,09409162 0,11340199 ! membrane depolarization GO:0051899 45 24 0,000 0,09409162 0,11334607 ! pallium development GO:0021543 56 24 0,000 0,09409162 0,11329021 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,09409162 0,1132344 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,09409162 0,11317864 ! platelet activation GO:0030168 41 24 0,000 0,09409162 0,11312295 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,09409162 0,1130673 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,09409162 0,11301171 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,09409162 0,11295618 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,09409162 0,1129007 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,09409162 0,11284528 ! negative regulation of catabolic process GO:0009895 52 24 0,000 0,09409162 0,11278991 ! regulation of amine transport GO:0051952 41 24 0,000 0,09409162 0,11273459 ! myeloid leukocyte differentiation GO:0002573 46 25 0,000 0,09781523 0,11713853 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,09781523 0,11708114 ! leukocyte adhesion GO:0007159 55 25 0,000 0,09781523 0,1170238 ! phototransduction GO:0007602 37 25 0,000 0,09781523 0,11696652 ! keratinization GO:0031424 37 25 0,000 0,09781523 0,1169093 ! vasculogenesis GO:0001570 49 25 0,000 0,09781523 0,11685213 ! vacuole organization GO:0007033 49 25 0,000 0,09781523 0,11679502 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,09781523 0,11673796 ! receptor metabolic process GO:0043112 53 25 0,000 0,09781523 0,11668096 ! chromosome condensation GO:0030261 48 25 0,000 0,09781523 0,11662401 ! regulation of behavior GO:0050795 48 25 0,000 0,09781523 0,11656712 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,09781523 0,11651029 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,09781523 0,11645351 ! immunoglobulin production GO:0002377 62 25 0,000 0,09781523 0,11639679 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,09781523 0,11634012 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,09781523 0,11628351 ! liver development GO:0001889 55 25 0,000 0,09781523 0,11622695 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,10152364 0,12057474 ! initiation of viral infection GO:0019059 60 26 0,000 0,10152364 0,12051616 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,10152364 0,12045762 ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,10152364 0,12039915 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,10152364 0,12034073 GO:0006479|protein amino acid methylation, ! regulation of transcription factor import into nucleus GO:0042990 58 26 0,000 0,10152364 0,12028237 ! microtubule organizing center organization GO:0031023 42 26 0,000 0,10152364 0,12022407 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,10152364 0,12016582 ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,10152364 0,12010763 ! digestive system process GO:0022600 49 26 0,000 0,10152364 0,12004949 ! regulation of cellular ketone metabolic process GO:0010565 51 26 0,000 0,10152364 0,11999141 ! osteoblast differentiation GO:0001649 63 26 0,000 0,10152364 0,11993339 ! neural crest cell development GO:0014032 59 26 0,000 0,10152364 0,11987542 GO:0014033|neural crest cell differentiation, ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,10152364 0,11981751 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,10152364 0,11975966 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,10152364 0,11970186 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,10152364 0,11964411 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,10152364 0,11958643 ! regulation of blood coagulation GO:0030193 46 26 0,000 0,10152364 0,11952879 ! regulation of osteoblast differentiation GO:0045667 68 26 0,000 0,10152364 0,11947122 ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,10152364 0,1194137 ! blastocyst development GO:0001824 50 26 0,000 0,10152364 0,11935623 ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,10152364 0,11929882 ! alditol metabolic process GO:0019400 44 26 0,000 0,10152364 0,11924147 ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,10152364 0,11918417 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,10152364 0,11912692 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,10521691 0,1234013 ! embryonic pattern specification GO:0009880 49 27 0,000 0,10521691 0,12334209 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,10521691 0,12328293 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,10521691 0,12322383 ! positive regulation of cell projection organization GO:0031346 66 27 0,000 0,10521691 0,12316479 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,10521691 0,1231058 ! iron ion transport GO:0006826 65 27 0,000 0,10521691 0,12304687 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,10521691 0,12298799 ! superoxide metabolic process GO:0006801 41 27 0,000 0,10521691 0,12292918 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,10521691 0,12287041 ! regulation of endothelial cell proliferation GO:0001936 60 27 0,000 0,10521691 0,12281171 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,10521691 0,12275306 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,10521691 0,12269447 ! neuron fate commitment GO:0048663 52 28 0,000 0,1088951 0,12692306 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,1088951 0,12686253 ! circadian rhythm GO:0007623 56 28 0,000 0,1088951 0,12680206 ! negative regulation of protein modification process GO:0031400 66 28 0,000 0,1088951 0,12674165 ! fat cell differentiation GO:0045444 57 28 0,000 0,1088951 0,1266813 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,1088951 0,126621 ! sperm motility GO:0030317 37 28 0,000 0,1088951 0,12656077 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,1088951 0,12650058 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,1088951 0,12644046 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,1088951 0,12638039 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,1088951 0,12632038 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,1088951 0,12626043 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,1088951 0,12620054 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,1088951 0,1261407 ! glutathione metabolic process GO:0006749 42 28 0,000 0,1088951 0,12608091 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,1088951 0,12602119 ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,1088951 0,12596152 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,1088951 0,12590191 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 0,000 0,11255827 0,13007562 ! translational initiation GO:0006413 66 29 0,000 0,11255827 0,13001412 ! cellular iron ion homeostasis GO:0006879 57 29 0,000 0,11255827 0,12995268 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,11255827 0,12989129 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! autophagy GO:0006914 47 29 0,000 0,11255827 0,12982996 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,11255827 0,12976869 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,11255827 0,12970748 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 0,000 0,11255827 0,12964633 ! synaptogenesis GO:0007416 46 29 0,000 0,11255827 0,12958523 ! negative regulation of neuron differentiation GO:0045665 46 29 0,000 0,11255827 0,12952419 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,11255827 0,12946321 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,11255827 0,12940229 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,11620649 0,13353361 ! negative regulation of protein complex assembly GO:0031333 68 30 0,000 0,11620649 0,13347083 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,11620649 0,13340811 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,11620649 0,13334545 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,11620649 0,13328285 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,11620649 0,1332203 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,11620649 0,13315782 ! acute-phase response GO:0006953 50 30 0,000 0,11620649 0,13309539 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,11620649 0,13303302 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,11620649 0,13297071 ! myofibril assembly GO:0030239 50 30 0,000 0,11620649 0,13290846 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 72 30 0,000 0,11620649 0,13284626 ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,11620649 0,13278413 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,11620649 0,13272205 ! cell fate determination GO:0001709 64 30 0,000 0,11620649 0,13266003 ! phospholipid transport GO:0015914 65 30 0,000 0,11620649 0,13259807 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,11620649 0,13253616 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,11620649 0,13247432 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,11620649 0,13241253 ! negative regulation of transcription regulator activity GO:0090048 57 30 0,000 0,11620649 0,1323508 GO:0043433|negative regulation of transcription factor activity, ! regulation of coagulation GO:0050818 52 30 0,000 0,11620649 0,13228913 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,11983982 0,13636175 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,11983982 0,13629826 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,11983982 0,13623484 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,11983982 0,13617148 ! regulation of innate immune response GO:0045088 57 31 0,000 0,11983982 0,13610817 ! peptide transport GO:0015833 60 31 0,000 0,11983982 0,13604492 ! iron ion homeostasis GO:0055072 60 31 0,000 0,11983982 0,13598173 ! detection of light stimulus GO:0009583 44 31 0,000 0,11983982 0,1359186 ! natural killer cell activation GO:0030101 50 31 0,000 0,11983982 0,13585553 ! eye morphogenesis GO:0048592 65 31 0,000 0,11983982 0,13579252 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,11983982 0,13572957 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,12345831 0,13976304 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,12345831 0,1396983 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,12345831 0,13963363 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,12345831 0,13956901 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,12345831 0,13950446 ! regulation of protein import into nucleus GO:0042306 69 32 0,000 0,12345831 0,13943996 ! muscle cell development GO:0055001 52 32 0,000 0,12345831 0,13937553 ! mesoderm formation GO:0001707 73 32 0,000 0,12345831 0,13931115 ! BMP signaling pathway GO:0030509 71 32 0,000 0,12345831 0,13924683 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,12345831 0,13918258 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,12345831 0,13911838 ! gene silencing GO:0016458 71 32 0,000 0,12345831 0,13905424 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,12706202 0,14304724 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,12706202 0,14298135 GO:0055092|sterol homeostasis, ! pigment biosynthetic process GO:0046148 73 33 0,000 0,12706202 0,14291552 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,12706202 0,14284975 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,12706202 0,14278404 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,12706202 0,1427184 ! leukocyte chemotaxis GO:0030595 55 33 0,000 0,12706202 0,14265281 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,12706202 0,14258728 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,12706202 0,14252182 ! negative regulation of protein transport GO:0051224 74 33 0,000 0,12706202 0,14245641 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,12706202 0,14239106 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,13065102 0,14634591 ! cholesterol transport GO:0030301 62 34 0,000 0,13065102 0,14627884 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,13065102 0,14621184 ! spliceosome assembly GO:0000245 75 34 0,000 0,13065102 0,14614489 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,13065102 0,146078 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,13065102 0,14601118 ! formation of primary germ layer GO:0001704 76 34 0,000 0,13065102 0,14594442 ! cell fate specification GO:0001708 56 34 0,000 0,13065102 0,14587771 ! negative regulation of MAP kinase activity GO:0043407 78 34 0,000 0,13065102 0,14581107 ! adult locomotory behavior GO:0008344 62 34 0,000 0,13065102 0,14574449 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,13422536 0,14966342 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,13422536 0,14959515 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,13422536 0,14952693 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,13422536 0,14945878 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,13422536 0,14939069 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,13422536 0,14932266 ! ceramide metabolic process GO:0006672 72 35 0,000 0,13422536 0,14925469 ! telencephalon development GO:0021537 81 35 0,000 0,13422536 0,14918679 ! sterol transport GO:0015918 63 35 0,000 0,13422536 0,14911895 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,13422536 0,14905116 ! placenta development GO:0001890 53 35 0,000 0,13422536 0,14898344 ! vesicle localization GO:0051648 70 35 0,000 0,13422536 0,14891579 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,13778511 0,15279574 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,13778511 0,15272642 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,13778511 0,15265715 ! negative regulation of DNA binding GO:0043392 67 36 0,000 0,13778511 0,15258795 ! protein targeting to membrane GO:0006612 75 36 0,000 0,13778511 0,15251882 ! regulation of proteolysis GO:0030162 77 36 0,000 0,13778511 0,15244974 ! cytokine production GO:0001816 68 36 0,000 0,13778511 0,15238073 ! embryonic organ development GO:0048568 67 36 0,000 0,13778511 0,15231178 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,13778511 0,15224289 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 0,000 0,14133032 0,1560895 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! regulation of smooth muscle cell proliferation GO:0048660 64 37 0,000 0,14133032 0,15601897 ! negative regulation of cell adhesion GO:0007162 94 37 0,000 0,14133032 0,1559485 ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,14133032 0,15587809 ! actomyosin structure organization GO:0031032 68 37 0,000 0,14133032 0,15580775 ! tissue remodeling GO:0048771 78 37 0,000 0,14133032 0,15573747 ! maintenance of protein location in cell GO:0032507 89 37 0,000 0,14133032 0,15566726 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,14133032 0,15559711 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,14486106 0,15941241 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,14486106 0,15934064 ! organic anion transport GO:0015711 82 38 0,000 0,14486106 0,15926893 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,14486106 0,15919728 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,14486106 0,1591257 ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,14486106 0,15905418 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,14486106 0,15898273 ! spermatid development GO:0007286 69 38 0,000 0,14486106 0,15891134 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,14837737 0,16269565 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,14837737 0,16262266 ! negative regulation of binding GO:0051100 71 39 0,000 0,14837737 0,16254974 ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,14837737 0,16247688 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,14837737 0,16240409 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,14837737 0,16233136 ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,14837737 0,16225869 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,15187933 0,16601396 GO:0006956|complement activation, ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,15187933 0,16593971 ! learning GO:0007612 82 40 0,000 0,15187933 0,16586553 ! nucleus organization GO:0006997 73 40 0,000 0,15187933 0,16579142 ! lipid homeostasis GO:0055088 75 40 0,000 0,15187933 0,16571737 ! mismatch repair GO:0006298 58 40 0,000 0,15187933 0,16564339 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,15187933 0,16556947 ! RNA export from nucleus GO:0006405 61 41 0,000 0,15536698 0,16929595 ! mRNA catabolic process GO:0006402 79 41 0,000 0,15536698 0,16922048 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,15536698 0,16914507 ! establishment or maintenance of cell polarity GO:0007163 96 41 0,000 0,15536698 0,16906972 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,15536698 0,16899445 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,15536698 0,16891924 ! feeding behavior GO:0007631 69 41 0,000 0,15536698 0,1688441 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,15536698 0,16876902 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 95 41 0,000 0,15536698 0,16869401 ! spermatid differentiation GO:0048515 73 41 0,000 0,15536698 0,16861907 ! RNA modification GO:0009451 64 41 0,000 0,15536698 0,1685442 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,15884039 0,17223571 ! ear morphogenesis GO:0042471 64 42 0,000 0,15884039 0,1721593 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,15884039 0,17208296 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,15884039 0,17200668 ! regulation of protein secretion GO:0050708 77 42 0,000 0,15884039 0,17193047 ! dorsal/ventral pattern formation GO:0009953 75 42 0,000 0,15884039 0,17185432 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,15884039 0,17177825 ! epithelial cell differentiation GO:0030855 83 43 0,000 0,16229961 0,17544157 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,16229961 0,17536397 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,16229961 0,17528645 ! regulation of tube size GO:0035150 76 43 0,000 0,16229961 0,17520899 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,16229961 0,1751316 ! glucose transport GO:0015758 66 43 0,000 0,16229961 0,17505428 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,16229961 0,17497703 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,16229961 0,17489984 ! ion transmembrane transport GO:0034220 79 43 0,000 0,16229961 0,17482273 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,1657447 0,17845496 ! positive regulation of response to external stimulus GO:0032103 88 44 0,000 0,1657447 0,17837635 ! hexose transport GO:0008645 68 44 0,000 0,1657447 0,1782978 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 0,000 0,1657447 0,17821933 ! striated muscle contraction GO:0006941 85 44 0,000 0,1657447 0,17814092 ! phagocytosis GO:0006909 105 44 0,000 0,1657447 0,17806258 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,1657447 0,17798431 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,16917572 0,18158888 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! keratinocyte differentiation GO:0030216 81 45 0,000 0,16917572 0,18150913 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,16917572 0,18142945 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,16917572 0,18134984 ! polyol metabolic process GO:0019751 77 45 0,000 0,16917572 0,1812703 ! maintenance of location in cell GO:0051651 101 45 0,000 0,16917572 0,18119083 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,17259273 0,18476952 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,17259273 0,18468859 ! leukocyte migration GO:0050900 75 46 0,000 0,17259273 0,18460772 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,17259273 0,18452693 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,17259273 0,18444621 ! cell growth GO:0016049 90 46 0,000 0,17259273 0,18436556 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,17599578 0,18791857 ! positive regulation of defense response GO:0031349 88 48 0,000 0,17938493 0,19145364 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,17938493 0,19137004 ! regulation of JAK-STAT cascade GO:0046425 76 48 0,000 0,17938493 0,19128651 ! cellular component disassembly GO:0022411 89 48 0,000 0,17938493 0,19120305 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 0,000 0,17938493 0,19111966 ! endosome transport GO:0016197 127 48 0,000 0,17938493 0,19103635 ! vascular process in circulatory system GO:0003018 85 48 0,000 0,17938493 0,19095311 ! regulation of inflammatory response GO:0050727 84 48 0,000 0,17938493 0,19086994 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,17938493 0,19078685 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,17938493 0,19070382 ! detection of stimulus involved in sensory perception GO:0050906 75 49 0,000 0,18276023 0,19420759 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,18276023 0,19412315 ! JNK cascade GO:0007254 106 49 0,000 0,18276023 0,19403879 ! protein homooligomerization GO:0051260 84 49 0,000 0,18276023 0,1939545 ! regulation of ion transport GO:0043269 86 50 0,000 0,18612175 0,19743614 ! induction of apoptosis by extracellular signals GO:0008624 99 50 0,000 0,18612175 0,19735045 ! endocrine system development GO:0035270 109 50 0,000 0,18612175 0,19726483 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,18612175 0,19717929 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,18612175 0,19709382 GO:0019724|B cell mediated immunity, ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,18612175 0,19700842 ! epidermal cell differentiation GO:0009913 87 50 0,000 0,18612175 0,1969231 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,18612175 0,19683785 ! regulation of cell projection organization GO:0031344 135 51 0,000 0,18946953 0,20029168 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,18946953 0,20020505 ! peptide metabolic process GO:0006518 80 51 0,000 0,18946953 0,20011849 ! detection of abiotic stimulus GO:0009582 80 51 0,000 0,18946953 0,20003201 ! Notch signaling pathway GO:0007219 111 52 0,000 0,19280364 0,20346406 ! excretion GO:0007588 87 52 0,000 0,19280364 0,20337621 ! DNA-dependent DNA replication GO:0006261 82 52 0,000 0,19280364 0,20328843 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,19280364 0,20320073 ! amino acid activation GO:0043038 98 52 0,000 0,19280364 0,20311311 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,19612413 0,20652209 ! inner ear development GO:0048839 89 53 0,000 0,19612413 0,20643311 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,19612413 0,2063442 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,19612413 0,20625538 ! cartilage development GO:0051216 99 53 0,000 0,19612413 0,20616663 ! regulation of translational initiation GO:0006446 87 54 0,000 0,19943105 0,20955271 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,19943105 0,20946262 ! neuromuscular process GO:0050905 107 54 0,000 0,19943105 0,2093726 ! regulation of muscle contraction GO:0006937 94 54 0,000 0,19943105 0,20928266 ! membrane fusion GO:0006944 122 54 0,000 0,19943105 0,20919281 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,19943105 0,20910302 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,19943105 0,20901332 ! RNA catabolic process GO:0006401 103 55 0,000 0,20272445 0,21237386 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,20272445 0,21228283 ! cell recognition GO:0008037 98 55 0,000 0,20272445 0,21219188 ! cell maturation GO:0048469 107 55 0,000 0,20272445 0,212101 ! regulation of protein polymerization GO:0032271 117 55 0,000 0,20272445 0,21201021 ! regulation of protein catabolic process GO:0042176 126 56 0,000 0,20600441 0,21534821 ! chloride transport GO:0006821 102 57 0,000 0,20927096 0,21866935 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,21252416 0,22197372 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,21252416 0,22187886 ! gastrulation GO:0007369 122 58 0,000 0,21252416 0,22178408 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,21252416 0,22168938 ! maintenance of location GO:0051235 124 58 0,000 0,21252416 0,22159476 ! nuclear export GO:0051168 110 59 0,000 0,21576407 0,22487697 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,21899074 0,2281426 ! regulation of endocytosis GO:0030100 104 60 0,000 0,21899074 0,22804535 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,21899074 0,22794818 ! adult behavior GO:0030534 104 60 0,000 0,21899074 0,2278511 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,22220423 0,23109618 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,22220423 0,23099784 ! cytokine-mediated signaling pathway GO:0019221 112 61 0,000 0,22220423 0,23089959 ! regulation of heart contraction GO:0008016 123 61 0,000 0,22220423 0,23080142 ! camera-type eye development GO:0043010 126 61 0,000 0,22220423 0,23070333 ! proton transport GO:0015992 117 61 0,000 0,22220423 0,23060532 ! negative regulation of response to stimulus GO:0048585 106 61 0,000 0,22220423 0,2305074 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,22540458 0,2337281 ! tRNA processing GO:0008033 102 62 0,000 0,22540458 0,23362893 ! regulation of protein complex assembly GO:0043254 132 63 0,000 0,22859186 0,23683202 ! mesoderm development GO:0007498 128 63 0,000 0,22859186 0,23673163 ! skeletal system morphogenesis GO:0048705 118 63 0,000 0,22859186 0,23663132 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,22859186 0,23653109 ! hydrogen transport GO:0006818 121 64 0,000 0,23176611 0,23971406 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,23176611 0,23961261 ! integrin-mediated signaling pathway GO:0007229 160 64 0,000 0,23176611 0,23951126 ! lymphocyte mediated immunity GO:0002449 122 65 0,000 0,23492739 0,24267552 ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,23492739 0,24257296 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,23492739 0,24247047 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,24121124 0,24885095 ! regulation of cellular response to stress GO:0080135 142 68 0,000 0,24433391 0,25196613 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,24433391 0,25185981 ! detection of external stimulus GO:0009581 102 68 0,000 0,24433391 0,25175359 ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,24433391 0,25164745 ! adaptive immune response GO:0002250 126 68 0,000 0,24433391 0,2515414 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! cell projection assembly GO:0030031 138 68 0,000 0,24433391 0,25143545 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,24744383 0,25452853 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 0,000 0,24744383 0,25442141 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,24744383 0,25431437 ! developmental maturation GO:0021700 128 69 0,000 0,24744383 0,25420743 ! single fertilization GO:0007338 83 69 0,000 0,24744383 0,25410057 ! cell redox homeostasis GO:0045454 114 70 0,000 0,25054103 0,257173 ! activation of immune response GO:0002253 120 70 0,000 0,25054103 0,25706498 ! protein maturation by peptide bond cleavage GO:0051605 118 70 0,000 0,25054103 0,25695706 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,25362557 0,26001144 ! cAMP-mediated signaling GO:0019933 124 71 0,000 0,25362557 0,25990238 ! carbohydrate transport GO:0008643 114 72 0,000 0,2566975 0,26294004 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 0,000 0,2566975 0,26282984 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,2566975 0,26271973 ! regulation of MAPKKK cascade GO:0043408 157 72 0,000 0,2566975 0,26260971 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,25975688 0,26562832 ! regulation of immune effector process GO:0002697 156 73 0,000 0,25975688 0,26551717 ! acute inflammatory response GO:0002526 118 74 0,000 0,26280375 0,26851926 ! amino acid transport GO:0006865 148 74 0,000 0,26280375 0,268407 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 0,000 0,26280375 0,26829484 ! transition metal ion transport GO:0000041 143 75 0,000 0,26583816 0,27127929 ! leukocyte mediated immunity GO:0002443 136 75 0,000 0,26583816 0,27116602 ! eye development GO:0001654 155 75 0,000 0,26583816 0,27105285 ! learning or memory GO:0007611 161 76 0,000 0,26886017 0,27401977 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,26886017 0,2739055 ! regulation of blood pressure GO:0008217 134 76 0,000 0,26886017 0,27379133 ! amine catabolic process GO:0009310 136 77 0,000 0,27186982 0,27674082 ! neurotransmitter transport GO:0006836 142 77 0,000 0,27186982 0,27662556 ! phosphoinositide metabolic process GO:0030384 146 77 0,000 0,27186982 0,2765104 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,27186982 0,27639533 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,27186982 0,27628036 ! positive regulation of ligase activity GO:0051351 130 77 0,000 0,27186982 0,27616548 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,27486717 0,27909414 ! antigen processing and presentation GO:0019882 117 78 0,000 0,27486717 0,27897819 ! fertilization GO:0009566 99 78 0,000 0,27486717 0,27886233 ! steroid biosynthetic process GO:0006694 146 79 0,000 0,27785227 0,2817738 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 0,000 0,28082516 0,28467048 ! activation of protein kinase activity GO:0032147 170 80 0,000 0,28082516 0,28455241 ! regulation of adenylate cyclase activity GO:0045761 165 83 0,000 0,2896711 0,29339407 ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,2896711 0,29327248 ! inorganic anion transport GO:0015698 156 83 0,000 0,2896711 0,29315099 ! digestion GO:0007586 130 84 0,000 0,29259566 0,29598808 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,29550827 0,29881072 ! regulation of cyclase activity GO:0031279 168 85 0,000 0,29550827 0,29868709 ! regulation of cAMP biosynthetic process GO:0030817 173 86 0,000 0,29840896 0,30149425 ! regulation of lyase activity GO:0051339 169 86 0,000 0,29840896 0,30136962 ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,3012978 0,30416137 ! nucleosome assembly GO:0006334 126 87 0,000 0,3012978 0,30403574 ! sensory perception of smell GO:0007608 117 88 0,000 0,30417482 0,30681217 ! chromatin assembly GO:0031497 128 88 0,000 0,30417482 0,30668555 ! regulation of cAMP metabolic process GO:0030814 182 89 0,000 0,30704007 0,30944674 ! cellular defense response GO:0006968 123 89 0,000 0,30704007 0,30931914 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,30989361 0,31206517 ! positive regulation of protein modification process GO:0031401 156 90 0,000 0,30989361 0,31193659 ! response to unfolded protein GO:0006986 139 90 0,000 0,30989361 0,31180811 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 0,000 0,31273548 0,31453799 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! defense response to bacterium GO:0042742 112 91 0,000 0,31273548 0,31440855 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,31556572 0,31712343 ! amine transport GO:0015837 181 93 0,000 0,31838439 0,31982445 ! vitamin metabolic process GO:0006766 153 93 0,000 0,31838439 0,319693 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,32119153 0,32237917 ! sterol metabolic process GO:0016125 166 94 0,000 0,32119153 0,32224678 ! regulation of defense response GO:0031347 171 95 0,000 0,32398718 0,32491818 ! nucleosome organization GO:0034728 143 95 0,000 0,32398718 0,32478486 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,32398718 0,32465164 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 0,000 0,32398718 0,32451853 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,32398718 0,32438553 ! regulation of nucleotide metabolic process GO:0006140 197 98 0,000 0,33230573 0,332578 ! mRNA transport GO:0051028 185 100 0,000 0,33779487 0,33793319 ! positive regulation of immune response GO:0050778 175 100 0,000 0,33779487 0,33779487