pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6679-VanDeVijver-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/vantveer-oligo_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! protein amino acid autophosphorylation GO:0046777 28 28 4,000 4,753E-08 8,76E-05 ! ER overload response GO:0006983 6 6 2,000 9,513E-07 8,766E-04 ! regulation of intracellular protein transport GO:0033157 25 25 3,000 1,921E-06 1,18E-03 ! regulation of nucleocytoplasmic transport GO:0046822 27 27 3,000 2,652E-06 1,222E-03 ! regulation of intracellular transport GO:0032386 31 31 3,000 4,706E-06 1,735E-03 ! positive regulation of nucleocytoplasmic transport GO:0046824 11 11 2,000 7,75E-06 2,381E-03 GO:0032388|positive regulation of intracellular transport, ! positive regulation of nitric oxide biosynthetic process GO:0045429 11 11 2,000 7,75E-06 2,04E-03 ! positive regulation of cell migration GO:0030335 36 36 3,000 8,698E-06 2,004E-03 ! lung development GO:0030324 38 37 3,000 9,727E-06 1,992E-03 ! respiratory tube development GO:0030323 40 39 3,000 1,205E-05 2,221E-03 ! respiratory system development GO:0060541 40 39 3,000 1,205E-05 2,019E-03 ! positive regulation of cell motion GO:0051272 39 39 3,000 1,205E-05 1,851E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 13 13 2,000 1,337E-05 1,895E-03 ! response to endoplasmic reticulum stress GO:0034976 13 13 2,000 1,337E-05 1,76E-03 ! protein tetramerization GO:0051262 13 13 2,000 1,337E-05 1,642E-03 ! positive regulation of epithelial cell proliferation GO:0050679 14 14 2,000 1,697E-05 1,955E-03 ! protein import into nucleus, translocation GO:0000060 15 15 2,000 2,116E-05 2,294E-03 ! ER-nuclear signaling pathway GO:0006984 15 15 2,000 2,116E-05 2,166E-03 ! cellular response to hormone stimulus GO:0032870 48 46 3,000 2,349E-05 2,278E-03 ! positive regulation of catabolic process GO:0009896 16 16 2,000 2,598E-05 2,394E-03 ! ossification GO:0001503 50 49 3,000 3,026E-05 2,656E-03 GO:0060348|bone development, ! positive regulation of MAP kinase activity GO:0043406 50 49 3,000 3,026E-05 2,535E-03 ! response to hormone stimulus GO:0009725 102 100 4,000 3,029E-05 2,427E-03 ! tissue remodeling GO:0048771 17 17 2,000 3,146E-05 2,416E-03 ! cell fate commitment GO:0045165 52 52 3,000 3,837E-05 2,828E-03 ! regulation of protein transport GO:0051223 53 53 3,000 4,139E-05 2,934E-03 GO:0070201|regulation of establishment of protein localization, ! regulation of protein localization GO:0032880 58 57 3,000 5,527E-05 3,773E-03 ! mammary gland development GO:0030879 23 21 2,000 6,092E-05 4,01E-03 ! peptidyl-amino acid modification GO:0018193 61 59 3,000 6,335E-05 4,026E-03 ! hormone-mediated signaling GO:0009755 22 22 2,000 7,036E-05 4,323E-03 ! regulation of MAP kinase activity GO:0043405 67 66 3,000 9,854E-05 5,858E-03 ! regulation of gene-specific transcription GO:0032583 25 25 2,000 1,043E-04 6,007E-03 ! regulation of cell migration GO:0030334 71 71 3,000 1,312E-04 7,325E-03 ! neuron fate specification GO:0048665 5 5 1,000 1,364E-04 7,393E-03 ! positive regulation of glucose metabolic process GO:0010907 5 5 1,000 1,364E-04 7,182E-03 ! forebrain regionalization GO:0021871 5 5 1,000 1,364E-04 6,982E-03 ! mRNA stabilization GO:0048255 5 5 1,000 1,364E-04 6,793E-03 GO:0043489|RNA stabilization, ! regulation of phospholipase A2 activity GO:0032429 5 5 1,000 1,364E-04 6,615E-03 ! protein heterooligomerization GO:0051291 5 5 1,000 1,364E-04 6,445E-03 ! negative regulation of focal adhesion formation GO:0051895 6 5 1,000 1,364E-04 6,284E-03 ! spinal cord motor neuron differentiation GO:0021522 5 5 1,000 1,364E-04 6,131E-03 GO:0021517|ventral spinal cord development, ! T cell lineage commitment GO:0002360 5 5 1,000 1,364E-04 5,985E-03 ! zymogen activation GO:0031638 5 5 1,000 1,364E-04 5,846E-03 ! negative regulation of neuroblast proliferation GO:0007406 5 5 1,000 1,364E-04 5,713E-03 ! ectodermal gut morphogenesis GO:0048567 5 5 1,000 1,364E-04 5,586E-03 GO:0007439|ectodermal gut development, ! embryonic gut development GO:0048566 5 5 1,000 1,364E-04 5,464E-03 ! positive regulation of blood vessel endothelial cell migration GO:0043536 5 5 1,000 1,364E-04 5,348E-03 ! branching morphogenesis of a tube GO:0048754 29 29 2,000 1,641E-04 6,299E-03 ! regulation of epithelial cell proliferation GO:0050678 29 29 2,000 1,641E-04 6,17E-03 ! positive regulation of protein transport GO:0051222 29 29 2,000 1,641E-04 6,047E-03 ! response to UV GO:0009411 29 29 2,000 1,641E-04 5,928E-03 ! regulation of locomotion GO:0040012 79 79 3,000 1,987E-04 7,042E-03 ! regulation of cell motion GO:0051270 79 79 3,000 1,987E-04 6,909E-03 ! regulation of DNA replication GO:0006275 32 31 2,000 2,008E-04 6,853E-03 ! N-terminal protein amino acid modification GO:0031365 6 6 1,000 2,041E-04 6,839E-03 GO:0018409|peptide or protein amino-terminal blocking, ! virus-host interaction GO:0019048 6 6 1,000 2,041E-04 6,717E-03 ! regulation of positive chemotaxis GO:0050926 6 6 1,000 2,041E-04 6,599E-03 GO:0050927|positive regulation of positive chemotaxis, ! negative regulation of T cell proliferation GO:0042130 6 6 1,000 2,041E-04 6,486E-03 GO:0070667|negative regulation of mast cell proliferation, ! regulation of vascular permeability GO:0043114 6 6 1,000 2,041E-04 6,376E-03 ! peptidyl-serine phosphorylation GO:0018105 6 6 1,000 2,041E-04 6,269E-03 ! regulation of bone resorption GO:0045124 6 6 1,000 2,041E-04 6,167E-03 ! G1 DNA damage checkpoint GO:0031571 6 6 1,000 2,041E-04 6,067E-03 ! regulation of T cell differentiation in the thymus GO:0033081 6 6 1,000 2,041E-04 5,971E-03 ! phosphoinositide 3-kinase cascade GO:0014065 6 6 1,000 2,041E-04 5,877E-03 ! regulation of focal adhesion formation GO:0051893 7 6 1,000 2,041E-04 5,787E-03 ! regulation of cellular carbohydrate catabolic process GO:0043471 6 6 1,000 2,041E-04 5,699E-03 GO:0043470|regulation of carbohydrate catabolic process, GO:0006110|regulation of glycolysis, ! regulation of embryonic development GO:0045995 6 6 1,000 2,041E-04 5,614E-03 ! localization within membrane GO:0051668 6 6 1,000 2,041E-04 5,532E-03 ! tube development GO:0035295 83 81 3,000 2,189E-04 5,846E-03 ! morphogenesis of a branching structure GO:0001763 32 32 2,000 2,21E-04 5,819E-03 ! regulation of cellular localization GO:0060341 86 85 3,000 2,637E-04 6,844E-03 ! regulation of bone remodeling GO:0046850 34 34 2,000 2,653E-04 6,791E-03 ! positive regulation of protein kinase activity GO:0045860 89 86 3,000 2,758E-04 6,964E-03 ! positive regulation of cellular catabolic process GO:0031331 7 7 1,000 2,851E-04 7,1E-03 ! digestive system development GO:0055123 7 7 1,000 2,851E-04 7,005E-03 GO:0048546|digestive tract morphogenesis, GO:0048547|gut morphogenesis, ! cell differentiation in spinal cord GO:0021515 7 7 1,000 2,851E-04 6,913E-03 ! regulation of mRNA processing GO:0050684 7 7 1,000 2,851E-04 6,823E-03 ! negative regulation of lymphocyte proliferation GO:0050672 7 7 1,000 2,851E-04 6,736E-03 GO:0032945|negative regulation of mononuclear cell proliferation, GO:0070664|negative regulation of leukocyte proliferation, ! response to X-ray GO:0010165 7 7 1,000 2,851E-04 6,651E-03 ! regulation of intracellular pH GO:0051453 7 7 1,000 2,851E-04 6,567E-03 ! positive regulation of carbohydrate metabolic process GO:0045913 7 7 1,000 2,851E-04 6,486E-03 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! cranial nerve development GO:0021545 7 7 1,000 2,851E-04 6,407E-03 ! response to gamma radiation GO:0010332 8 7 1,000 2,851E-04 6,33E-03 ! negative regulation of cell-substrate adhesion GO:0010812 8 7 1,000 2,851E-04 6,255E-03 GO:0001953|negative regulation of cell-matrix adhesion, ! regulation of mRNA stability GO:0043488 7 7 1,000 2,851E-04 6,181E-03 ! negative regulation of T cell activation GO:0050868 7 7 1,000 2,851E-04 6,109E-03 ! heart development GO:0007507 90 87 3,000 2,884E-04 6,109E-03 ! mesoderm development GO:0007498 35 35 2,000 2,895E-04 6,062E-03 ! regulation of tissue remodeling GO:0034103 35 35 2,000 2,895E-04 5,994E-03 ! positive regulation of transferase activity GO:0051347 91 88 3,000 3,013E-04 6,171E-03 GO:0033674|positive regulation of kinase activity, ! negative regulation of bone remodeling GO:0046851 8 8 1,000 3,792E-04 7,68E-03 ! positive regulation of endothelial cell migration GO:0010595 8 8 1,000 3,792E-04 7,597E-03 ! sex determination GO:0007530 8 8 1,000 3,792E-04 7,515E-03 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 8 8 1,000 3,792E-04 7,435E-03 ! peptidyl-serine modification GO:0018209 8 8 1,000 3,792E-04 7,357E-03 ! positive regulation of leukocyte migration GO:0002687 8 8 1,000 3,792E-04 7,28E-03 ! regulation of RNA stability GO:0043487 8 8 1,000 3,792E-04 7,205E-03 ! regulation of generation of precursor metabolites and energy GO:0043467 8 8 1,000 3,792E-04 7,132E-03 ! release of cytochrome c from mitochondria GO:0001836 9 8 1,000 3,792E-04 7,06E-03 ! protein oligomerization GO:0051259 39 39 2,000 4,001E-04 7,375E-03 ! ectoderm development GO:0007398 99 99 3,000 4,729E-04 8,629E-03 ! embryonic pattern specification GO:0009880 10 9 1,000 4,864E-04 8,789E-03 ! regulation of nitric-oxide synthase activity GO:0050999 9 9 1,000 4,864E-04 8,704E-03 ! positive regulation of endothelial cell proliferation GO:0001938 9 9 1,000 4,864E-04 8,62E-03 ! platelet-derived growth factor receptor signaling pathway GO:0048008 9 9 1,000 4,864E-04 8,538E-03 ! branching involved in ureteric bud morphogenesis GO:0001658 9 9 1,000 4,864E-04 8,458E-03 GO:0060675|ureteric bud morphogenesis, ! positive regulation of protein import into nucleus GO:0042307 9 9 1,000 4,864E-04 8,379E-03 ! regulation of cellular pH GO:0030641 9 9 1,000 4,864E-04 8,301E-03 ! negative regulation of tissue remodeling GO:0034104 9 9 1,000 4,864E-04 8,225E-03 ! regulation of leukocyte migration GO:0002685 9 9 1,000 4,864E-04 8,15E-03 ! regulation of blood vessel endothelial cell migration GO:0043535 9 9 1,000 4,864E-04 8,077E-03 ! protein import into nucleus GO:0006606 44 44 2,000 5,727E-04 9,423E-03 ! regulation of glucose metabolic process GO:0010906 10 10 1,000 6,066E-04 9,894E-03 ! negative regulation of nucleocytoplasmic transport GO:0046823 10 10 1,000 6,066E-04 9,807E-03 ! apoptotic mitochondrial changes GO:0008637 11 10 1,000 6,066E-04 9,722E-03 ! neuromuscular junction development GO:0007528 10 10 1,000 6,066E-04 9,638E-03 ! nerve development GO:0021675 10 10 1,000 6,066E-04 9,556E-03 ! gut development GO:0048565 10 10 1,000 6,066E-04 9,475E-03 ! embryonic organ morphogenesis GO:0048562 10 10 1,000 6,066E-04 9,395E-03 ! positive regulation of neuron apoptosis GO:0043525 10 10 1,000 6,066E-04 9,317E-03 ! negative regulation of homeostatic process GO:0032845 10 10 1,000 6,066E-04 9,24E-03 ! nuclear import GO:0051170 45 45 2,000 6,12E-04 9,246E-03 ! tube morphogenesis GO:0035239 47 46 2,000 6,531E-04 9,786E-03 ! regulation of catabolic process GO:0009894 48 47 2,000 6,959E-04 0,01034266 ! spinal cord development GO:0021510 11 11 1,000 7,397E-04 0,01090639 ! cellular response to starvation GO:0009267 11 11 1,000 7,397E-04 0,01081984 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 11 11 1,000 7,397E-04 0,01073464 ! G1/S transition checkpoint GO:0031575 12 11 1,000 7,397E-04 0,01065078 ! interaction with host GO:0051701 11 11 1,000 7,397E-04 0,01056821 ! regulation of monooxygenase activity GO:0032768 11 11 1,000 7,397E-04 0,01048692 ! regulation of cellular carbohydrate metabolic process GO:0010675 11 11 1,000 7,397E-04 0,01040686 GO:0006109|regulation of carbohydrate metabolic process, ! hindbrain development GO:0030902 11 11 1,000 7,397E-04 0,01032802 ! proximal/distal pattern formation GO:0009954 11 11 1,000 7,397E-04 0,01025037 ! negative regulation of lymphocyte activation GO:0051250 11 11 1,000 7,397E-04 0,01017387 ! protein localization in nucleus GO:0034504 48 48 2,000 7,404E-04 0,0101079 ! gland development GO:0048732 51 49 2,000 7,867E-04 0,0106612 ! cell cycle arrest GO:0007050 49 49 2,000 7,867E-04 0,01058338 ! regulation of DNA metabolic process GO:0051052 51 50 2,000 8,348E-04 0,01114936 ! regulation of neurogenesis GO:0050767 51 50 2,000 8,348E-04 0,01106915 ! positive regulation of protein catabolic process GO:0045732 12 12 1,000 8,856E-04 0,01165828 ! osteoblast differentiation GO:0001649 12 12 1,000 8,856E-04 0,0115756 ! cellular monovalent inorganic cation homeostasis GO:0030004 12 12 1,000 8,856E-04 0,01149408 ! response to light stimulus GO:0009416 53 52 2,000 9,366E-04 0,01207129 ! response to hypoxia GO:0001666 53 53 2,000 9,903E-04 0,01267492 ! positive regulation of DNA replication GO:0045740 14 13 1,000 1,044E-03 0,01327198 ! positive regulation of smooth muscle cell proliferation GO:0048661 13 13 1,000 1,044E-03 0,01318108 ! gluconeogenesis GO:0006094 13 13 1,000 1,044E-03 0,01309141 ! vasculogenesis GO:0001570 13 13 1,000 1,044E-03 0,01300295 ! mitochondrial membrane organization GO:0007006 13 13 1,000 1,044E-03 0,01291569 ! negative regulation of DNA replication GO:0008156 13 13 1,000 1,044E-03 0,01282958 ! ureteric bud development GO:0001657 13 13 1,000 1,044E-03 0,01274462 ! cell aging GO:0007569 13 13 1,000 1,044E-03 0,01266077 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 13 13 1,000 1,044E-03 0,01257802 ! regulation of endothelial cell migration GO:0010594 13 13 1,000 1,044E-03 0,01249634 ! positive regulation of locomotion GO:0040017 13 13 1,000 1,044E-03 0,01241572 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, GO:0050920|regulation of chemotaxis, ! negative regulation of intracellular transport GO:0032387 13 13 1,000 1,044E-03 0,01233614 ! negative regulation of leukocyte activation GO:0002695 13 13 1,000 1,044E-03 0,01225756 ! regulation of cell-substrate adhesion GO:0010810 14 13 1,000 1,044E-03 0,01217998 GO:0001952|regulation of cell-matrix adhesion, ! camera-type eye morphogenesis GO:0048593 13 13 1,000 1,044E-03 0,01210338 ! tissue homeostasis GO:0001894 13 13 1,000 1,044E-03 0,01202773 GO:0048871|multicellular organismal homeostasis, ! response to oxygen levels GO:0070482 55 54 2,000 1,046E-03 0,0119734 ! in utero embryonic development GO:0001701 55 55 2,000 1,104E-03 0,01255452 ! regulation of cell adhesion GO:0030155 56 55 2,000 1,104E-03 0,0124775 ! reproductive developmental process GO:0003006 56 56 2,000 1,163E-03 0,01307061 ! regulation of nervous system development GO:0051960 57 56 2,000 1,163E-03 0,0129914 ! neuron fate commitment GO:0048663 14 14 1,000 1,215E-03 0,01349376 ! pyruvate metabolic process GO:0006090 14 14 1,000 1,215E-03 0,01341296 ! protein amino acid acylation GO:0043543 14 14 1,000 1,215E-03 0,01333312 ! regulation of behavior GO:0050795 14 14 1,000 1,215E-03 0,01325423 ! base-excision repair GO:0006284 14 14 1,000 1,215E-03 0,01317626 ! formation of primary germ layer GO:0001704 14 14 1,000 1,215E-03 0,01309921 GO:0001707|mesoderm formation, ! positive regulation of osteoblast differentiation GO:0045669 14 14 1,000 1,215E-03 0,01302305 ! regulation of cell development GO:0060284 60 59 2,000 1,354E-03 0,01442254 ! protein localization in organelle GO:0033365 59 59 2,000 1,354E-03 0,01433965 ! odontogenesis of dentine-containing tooth GO:0042475 15 15 1,000 1,399E-03 0,01473471 ! insulin receptor signaling pathway GO:0008286 17 15 1,000 1,399E-03 0,01465099 ! ovarian follicle development GO:0001541 15 15 1,000 1,399E-03 0,01456822 ! mesoderm morphogenesis GO:0048332 15 15 1,000 1,399E-03 0,01448638 ! response to starvation GO:0042594 15 15 1,000 1,399E-03 0,01440545 ! response to ionizing radiation GO:0010212 16 15 1,000 1,399E-03 0,01432542 ! response to mechanical stimulus GO:0009612 15 15 1,000 1,399E-03 0,01424627 ! negative regulation of cell activation GO:0050866 15 15 1,000 1,399E-03 0,014168 ! protein import GO:0017038 62 62 2,000 1,563E-03 0,0157432 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 16 16 1,000 1,595E-03 0,01597883 ! fatty acid beta-oxidation GO:0006635 16 16 1,000 1,595E-03 0,01589245 ! cell fate specification GO:0001708 16 16 1,000 1,595E-03 0,01580701 ! cellular response to nutrient levels GO:0031669 16 16 1,000 1,595E-03 0,01572248 ! angiogenesis GO:0001525 65 64 2,000 1,713E-03 0,01679776 ! regulation of fibroblast proliferation GO:0048145 17 17 1,000 1,804E-03 0,01758935 ! regulation of smooth muscle cell proliferation GO:0048660 17 17 1,000 1,804E-03 0,01749677 ! positive regulation of cell adhesion GO:0045785 17 17 1,000 1,804E-03 0,01740517 ! myelination GO:0042552 17 17 1,000 1,804E-03 0,01731451 ! embryonic skeletal system morphogenesis GO:0048704 17 17 1,000 1,804E-03 0,0172248 ! negative regulation of cell development GO:0010721 18 17 1,000 1,804E-03 0,01713601 GO:0050768|negative regulation of neurogenesis, ! regulation of oxidoreductase activity GO:0051341 17 17 1,000 1,804E-03 0,01704814 ! regulation of osteoblast differentiation GO:0045667 17 17 1,000 1,804E-03 0,01696116 ! embryonic organ development GO:0048568 17 17 1,000 1,804E-03 0,01687506 ! negative regulation of cell differentiation GO:0045596 68 67 2,000 1,955E-03 0,01820133 ! regulation of cellular catabolic process GO:0031329 18 18 1,000 2,025E-03 0,01875004 ! epidermal growth factor receptor signaling pathway GO:0007173 18 18 1,000 2,025E-03 0,01865629 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 18 18 1,000 2,025E-03 0,01856348 ! telencephalon development GO:0021537 19 18 1,000 2,025E-03 0,01847158 ! hexose biosynthetic process GO:0019319 18 18 1,000 2,025E-03 0,01838059 ! B cell differentiation GO:0030183 18 18 1,000 2,025E-03 0,01829048 ! cellular response to extracellular stimulus GO:0031668 18 18 1,000 2,025E-03 0,01820126 ! ensheathment of neurons GO:0007272 18 18 1,000 2,025E-03 0,01811291 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 18 18 1,000 2,025E-03 0,01802541 ! symbiosis, encompassing mutualism through parasitism GO:0044403 18 18 1,000 2,025E-03 0,01793874 ! response to radiation GO:0009314 70 68 2,000 2,041E-03 0,01799413 ! positive regulation of transport GO:0051050 71 70 2,000 2,218E-03 0,01946314 ! DNA damage checkpoint GO:0000077 19 19 1,000 2,257E-03 0,01971828 ! negative regulation of DNA metabolic process GO:0051053 19 19 1,000 2,257E-03 0,01962527 ! regulation of pH GO:0006885 19 19 1,000 2,257E-03 0,01953314 ! regulation of endothelial cell proliferation GO:0001936 19 19 1,000 2,257E-03 0,01944186 ! peptidyl-tyrosine phosphorylation GO:0018108 20 19 1,000 2,257E-03 0,01935143 ! metanephros development GO:0001656 19 19 1,000 2,257E-03 0,01926184 ! peripheral nervous system development GO:0007422 19 19 1,000 2,257E-03 0,01917308 ! dorsal/ventral pattern formation GO:0009953 19 19 1,000 2,257E-03 0,01908513 ! eye morphogenesis GO:0048592 19 19 1,000 2,257E-03 0,01899798 ! regulation of cell shape GO:0008360 21 19 1,000 2,257E-03 0,01891163 ! positive regulation of hydrolase activity GO:0051345 72 72 2,000 2,404E-03 0,02004932 ! negative regulation of cell adhesion GO:0007162 21 20 1,000 2,503E-03 0,02077533 ! neural tube development GO:0021915 21 20 1,000 2,503E-03 0,02068216 ! nucleus organization GO:0006997 20 20 1,000 2,503E-03 0,02058983 ! positive regulation of gene-specific transcription GO:0043193 20 20 1,000 2,503E-03 0,02049832 ! peptidyl-tyrosine modification GO:0018212 21 20 1,000 2,503E-03 0,02040762 ! lipid oxidation GO:0034440 20 20 1,000 2,503E-03 0,02031772 GO:0019395|fatty acid oxidation, ! monosaccharide biosynthetic process GO:0046364 20 20 1,000 2,503E-03 0,02022861 ! G1/S transition of mitotic cell cycle GO:0000082 21 21 1,000 2,76E-03 0,02220869 ! protein amino acid lipidation GO:0006497 21 21 1,000 2,76E-03 0,02211213 ! DNA integrity checkpoint GO:0031570 21 21 1,000 2,76E-03 0,02201641 ! regulation of protein import into nucleus GO:0042306 21 21 1,000 2,76E-03 0,02192151 ! regulation of action potential in neuron GO:0019228 21 21 1,000 2,76E-03 0,02182742 ! negative regulation of hydrolase activity GO:0051346 21 21 1,000 2,76E-03 0,02173414 ! cellular response to insulin stimulus GO:0032869 23 21 1,000 2,76E-03 0,02164166 ! negative regulation of protein transport GO:0051224 21 21 1,000 2,76E-03 0,02154996 ! positive regulation of DNA metabolic process GO:0051054 23 22 1,000 3,028E-03 0,02355021 ! odontogenesis GO:0042476 22 22 1,000 3,028E-03 0,02345126 ! embryonic skeletal system development GO:0048706 22 22 1,000 3,028E-03 0,02335314 ! ovulation cycle process GO:0022602 22 22 1,000 3,028E-03 0,02325584 ! fatty acid catabolic process GO:0009062 23 22 1,000 3,028E-03 0,02315934 ! nuclear transport GO:0051169 79 79 2,000 3,132E-03 0,02385594 GO:0006913|nucleocytoplasmic transport, ! response to estrogen stimulus GO:0043627 23 23 1,000 3,309E-03 0,02509792 ! mitotic cell cycle checkpoint GO:0007093 24 23 1,000 3,309E-03 0,02499506 ! lipoprotein biosynthetic process GO:0042158 23 23 1,000 3,309E-03 0,02489304 ! positive regulation of growth GO:0045927 23 23 1,000 3,309E-03 0,02479185 ! female gonad development GO:0008585 23 23 1,000 3,309E-03 0,02469148 ! monovalent inorganic cation homeostasis GO:0055067 23 23 1,000 3,309E-03 0,02459191 ! calcium-mediated signaling GO:0019722 23 23 1,000 3,309E-03 0,02449315 ! MAPKKK cascade GO:0000165 82 81 2,000 3,363E-03 0,02479076 ! mitochondrial transport GO:0006839 24 24 1,000 3,602E-03 0,02644547 ! regulation of action potential GO:0001508 24 24 1,000 3,602E-03 0,02634053 ! gliogenesis GO:0042063 24 24 1,000 3,602E-03 0,02623642 ! glucose homeostasis GO:0042593 24 24 1,000 3,602E-03 0,02613313 GO:0033500|carbohydrate homeostasis, ! T cell differentiation GO:0030217 24 24 1,000 3,602E-03 0,02603064 ! ovulation cycle GO:0042698 24 24 1,000 3,602E-03 0,02592896 ! epithelial tube morphogenesis GO:0060562 25 24 1,000 3,602E-03 0,02582807 ! glucan metabolic process GO:0044042 25 24 1,000 3,602E-03 0,02572796 GO:0006073|cellular glucan metabolic process, GO:0005977|glycogen metabolic process, ! blood vessel morphogenesis GO:0048514 84 83 2,000 3,603E-03 0,0256409 ! alcohol biosynthetic process GO:0046165 25 25 1,000 3,906E-03 0,02768577 ! development of primary female sexual characteristics GO:0046545 25 25 1,000 3,906E-03 0,02757969 GO:0046660|female sex differentiation, ! regulation of T cell proliferation GO:0042129 25 25 1,000 3,906E-03 0,02747443 ! gastrulation GO:0007369 25 25 1,000 3,906E-03 0,02736996 ! heart morphogenesis GO:0003007 25 25 1,000 3,906E-03 0,02726629 ! negative regulation of immune system process GO:0002683 25 25 1,000 3,906E-03 0,02716339 ! regulation of anatomical structure morphogenesis GO:0022603 90 86 2,000 3,984E-03 0,02760033 ! transforming growth factor beta receptor signaling pathway GO:0007179 26 26 1,000 4,221E-03 0,02913893 ! induction of apoptosis by intracellular signals GO:0008629 26 26 1,000 4,221E-03 0,0290302 ! regulation of T cell differentiation GO:0045580 26 26 1,000 4,221E-03 0,02892228 ! double-strand break repair GO:0006302 27 26 1,000 4,221E-03 0,02881516 ! response to insulin stimulus GO:0032868 28 26 1,000 4,221E-03 0,02870884 ! synapse organization GO:0050808 26 26 1,000 4,221E-03 0,02860329 ! brain development GO:0007420 91 90 2,000 4,527E-03 0,03056402 ! energy reserve metabolic process GO:0006112 28 27 1,000 4,549E-03 0,03059505 ! activation of caspase activity GO:0006919 27 27 1,000 4,549E-03 0,03048379 ! negative regulation of cell cycle GO:0045786 92 91 2,000 4,67E-03 0,03118441 ! developmental growth GO:0048589 28 28 1,000 4,887E-03 0,0325162 ! regulation of mast cell proliferation GO:0070666 28 28 1,000 4,887E-03 0,03239924 ! tissue morphogenesis GO:0048729 94 93 2,000 4,964E-03 0,03278767 ! blood vessel development GO:0001568 95 94 2,000 5,114E-03 0,03366342 ! pattern specification process GO:0007389 96 94 2,000 5,114E-03 0,03354362 ! positive regulation of cell cycle GO:0045787 29 29 1,000 5,237E-03 0,03422616 ! viral reproductive process GO:0022415 29 29 1,000 5,237E-03 0,03410522 ! regulation of lymphocyte proliferation GO:0050670 29 29 1,000 5,237E-03 0,03398513 GO:0032944|regulation of mononuclear cell proliferation, GO:0070663|regulation of leukocyte proliferation, ! regulation of cell growth GO:0001558 97 96 2,000 5,424E-03 0,03507727 ! vasculature development GO:0001944 97 96 2,000 5,424E-03 0,03495462 ! positive regulation of peptidase activity GO:0010952 30 30 1,000 5,598E-03 0,03594862 GO:0043280|positive regulation of caspase activity, ! activation of phospholipase C activity GO:0007202 30 30 1,000 5,598E-03 0,0358238 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of response to external stimulus GO:0032103 30 30 1,000 5,598E-03 0,03569984 ! skeletal system morphogenesis GO:0048705 31 30 1,000 5,598E-03 0,03557674 ! regulation of ossification GO:0030278 30 30 1,000 5,598E-03 0,03545448 ! vascular process in circulatory system GO:0003018 31 30 1,000 5,598E-03 0,03533306 ! skeletal muscle fiber development GO:0048741 31 31 1,000 5,97E-03 0,03755381 ! B cell activation GO:0042113 31 31 1,000 5,97E-03 0,03742608 ! lipoprotein metabolic process GO:0042157 31 31 1,000 5,97E-03 0,03729921 ! positive regulation of phospholipase activity GO:0010518 31 31 1,000 5,97E-03 0,0371732 ! aging GO:0007568 32 31 1,000 5,97E-03 0,03704804 ! camera-type eye development GO:0043010 31 31 1,000 5,97E-03 0,03692371 ! negative regulation of cell growth GO:0030308 32 32 1,000 6,354E-03 0,03916275 ! muscle fiber development GO:0048747 32 32 1,000 6,354E-03 0,03903221 ! lipid modification GO:0030258 32 32 1,000 6,354E-03 0,03890253 ! regulation of phospholipase activity GO:0010517 32 32 1,000 6,354E-03 0,03877372 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 32 32 1,000 6,354E-03 0,03864575 ! regulation of lymphocyte differentiation GO:0045619 32 32 1,000 6,354E-03 0,03851863 ! kidney development GO:0001822 32 32 1,000 6,354E-03 0,03839234 ! positive regulation of lipase activity GO:0060193 32 32 1,000 6,354E-03 0,03826687 ! negative regulation of cell size GO:0045792 33 33 1,000 6,748E-03 0,04050909 ! regulation of neuron differentiation GO:0045664 34 33 1,000 6,748E-03 0,04037756 ! regulation of neuron apoptosis GO:0043523 34 33 1,000 6,748E-03 0,04024689 ! regulation of angiogenesis GO:0045765 35 34 1,000 7,153E-03 0,0425258 ! cellular polysaccharide metabolic process GO:0044264 35 34 1,000 7,153E-03 0,04238906 ! regulation of protein catabolic process GO:0042176 35 34 1,000 7,153E-03 0,0422532 ! response to peptide hormone stimulus GO:0043434 36 34 1,000 7,153E-03 0,0421182 ! viral reproduction GO:0016032 34 34 1,000 7,153E-03 0,04198407 ! regulation of cyclin-dependent protein kinase activity GO:0000079 35 35 1,000 7,569E-03 0,04428456 ! multicellular organism reproduction GO:0032504 36 35 1,000 7,569E-03 0,04414442 GO:0048609|reproductive process in a multicellular organism, ! regulation of cell morphogenesis GO:0022604 38 35 1,000 7,569E-03 0,04400516 ! positive regulation of phosphorylation GO:0042327 35 35 1,000 7,569E-03 0,04386678 ! response to steroid hormone stimulus GO:0048545 35 35 1,000 7,569E-03 0,04372926 ! gonad development GO:0008406 36 36 1,000 7,996E-03 0,04605017 ! regulation of lipase activity GO:0060191 36 36 1,000 7,996E-03 0,04590671 ! embryonic limb morphogenesis GO:0030326 36 36 1,000 7,996E-03 0,04576414 GO:0035113|embryonic appendage morphogenesis, ! positive regulation of phosphorus metabolic process GO:0010562 36 36 1,000 7,996E-03 0,04562246 GO:0045937|positive regulation of phosphate metabolic process, ! negative regulation of protein kinase activity GO:0006469 37 37 1,000 8,433E-03 0,04796946 ! response to drug GO:0042493 37 37 1,000 8,433E-03 0,04782187 ! eye development GO:0001654 37 37 1,000 8,433E-03 0,04767517 ! negative regulation of growth GO:0045926 37 37 1,000 8,433E-03 0,04752938 ! DNA damage response, signal transduction GO:0042770 37 37 1,000 8,433E-03 0,04738447 ! adaptive immune response GO:0002250 37 37 1,000 8,433E-03 0,04724044 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! negative regulation of kinase activity GO:0033673 38 38 1,000 8,881E-03 0,04959892 ! urogenital system development GO:0001655 38 38 1,000 8,881E-03 0,04944907 ! axon guidance GO:0007411 39 38 1,000 8,881E-03 0,04930013 ! regulation of homeostatic process GO:0032844 38 38 1,000 8,881E-03 0,04915208 ! activation of MAPK activity GO:0000187 39 39 1,000 9,339E-03 0,05153448 ! nucleotide-excision repair GO:0006289 40 39 1,000 9,339E-03 0,05138065 ! lymphocyte differentiation GO:0030098 39 39 1,000 9,339E-03 0,05122773 ! limb development GO:0060173 39 39 1,000 9,339E-03 0,05107572 GO:0048736|appendage development, GO:0035107|appendage morphogenesis, ! regulation of MAPKKK cascade GO:0043408 41 39 1,000 9,339E-03 0,05092461 ! regulation of cAMP metabolic process GO:0030814 40 40 1,000 9,808E-03 0,05332325 ! negative regulation of transferase activity GO:0051348 40 40 1,000 9,808E-03 0,05316642 ! cell cycle checkpoint GO:0000075 42 41 1,000 0,01028741 0,05560028 ! regulation of caspase activity GO:0043281 41 41 1,000 0,01028741 0,0554377 ! regulation of cyclic nucleotide metabolic process GO:0030799 42 42 1,000 0,01077684 0,05790585 ! regulation of endopeptidase activity GO:0052548 42 42 1,000 0,01077684 0,05773752 ! development of primary sexual characteristics GO:0045137 42 42 1,000 0,01077684 0,05757017 ! protein ubiquitination GO:0016567 43 42 1,000 0,01077684 0,05740378 ! forebrain development GO:0030900 43 42 1,000 0,01077684 0,05723835 ! reproductive structure development GO:0048608 43 43 1,000 0,01127644 0,05971976 ! mitochondrion organization GO:0007005 44 43 1,000 0,01127644 0,05954865 ! regulation of nucleotide metabolic process GO:0006140 43 43 1,000 0,01127644 0,05937851 ! phosphoinositide-mediated signaling GO:0048015 45 45 1,000 0,01230587 0,06461458 ! Wnt receptor signaling pathway GO:0016055 46 45 1,000 0,01230587 0,06443102 ! protein processing GO:0016485 45 45 1,000 0,01230587 0,06424849 ! regulation of peptidase activity GO:0052547 46 46 1,000 0,01283554 0,06682459 ! regulation of membrane potential GO:0042391 46 46 1,000 0,01283554 0,06663635 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 47 47 1,000 0,01337508 0,06924235 ! sex differentiation GO:0007548 47 47 1,000 0,01337508 0,0690484 ! rhythmic process GO:0048511 47 47 1,000 0,01337508 0,06885552 ! leukocyte differentiation GO:0002521 50 49 1,000 0,01448347 0,07435385 ! cellular lipid catabolic process GO:0044242 50 49 1,000 0,01448347 0,07414731 ! skeletal muscle tissue development GO:0007519 50 49 1,000 0,01448347 0,07394191 GO:0060538|skeletal muscle organ development, ! negative regulation of transport GO:0051051 51 50 1,000 0,01505216 0,07663296 ! T cell activation GO:0042110 51 50 1,000 0,01505216 0,07642185 ! anatomical structure homeostasis GO:0060249 51 50 1,000 0,01505216 0,0762119 ! anterior/posterior pattern formation GO:0009952 51 50 1,000 0,01505216 0,0760031 ! protein modification by small protein conjugation GO:0032446 52 51 1,000 0,01563042 0,07870728 ! interphase of mitotic cell cycle GO:0051329 52 51 1,000 0,01563042 0,07849282 GO:0051325|interphase, ! protein maturation GO:0051604 51 51 1,000 0,01563042 0,07827952 ! carbohydrate biosynthetic process GO:0016051 53 53 1,000 0,01681534 0,08398557 ! regulation of T cell activation GO:0050863 53 53 1,000 0,01681534 0,08375858 ! negative regulation of multicellular organismal process GO:0051241 55 54 1,000 0,01742186 0,08654577 ! protein modification by small protein conjugation or removal GO:0070647 56 55 1,000 0,01803764 0,08936391 ! extracellular structure organization GO:0043062 56 56 1,000 0,01866262 0,09221238 ! rRNA transcription GO:0009303 5 5 0,000 0,01875849 0,09243821 ! positive regulation of protein ubiquitination GO:0031398 5 5 0,000 0,01875849 0,09219171 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 5 5 0,000 0,01875849 0,09194652 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 5 5 0,000 0,01875849 0,09170263 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! hemoglobin biosynthetic process GO:0042541 5 5 0,000 0,01875849 0,09146003 ! reproductive cellular process GO:0048610 5 5 0,000 0,01875849 0,09121871 ! negative regulation of blood pressure GO:0045776 6 5 0,000 0,01875849 0,09097866 ! prostate gland development GO:0030850 5 5 0,000 0,01875849 0,09073987 ! metencephalon development GO:0022037 5 5 0,000 0,01875849 0,09050233 ! water transport GO:0006833 5 5 0,000 0,01875849 0,09026603 GO:0042044|fluid transport, ! DNA synthesis during DNA repair GO:0000731 5 5 0,000 0,01875849 0,09003096 ! positive regulation of B cell proliferation GO:0030890 5 5 0,000 0,01875849 0,08979712 ! glycerol metabolic process GO:0006071 5 5 0,000 0,01875849 0,08956448 ! regulation of cellular amine metabolic process GO:0033238 5 5 0,000 0,01875849 0,08933305 GO:0042053|regulation of dopamine metabolic process, GO:0042069|regulation of catecholamine metabolic process, ! meiotic prophase I GO:0007128 5 5 0,000 0,01875849 0,08910281 GO:0051324|prophase, ! cell volume homeostasis GO:0006884 5 5 0,000 0,01875849 0,08887375 ! regulation of epidermal growth factor receptor activity GO:0007176 5 5 0,000 0,01875849 0,08864587 GO:0010469|regulation of receptor activity, ! regulation of long-term neuronal synaptic plasticity GO:0048169 5 5 0,000 0,01875849 0,08841916 ! filopodium assembly GO:0046847 7 5 0,000 0,01875849 0,0881936 GO:0030035|microspike assembly, ! CTP metabolic process GO:0046036 5 5 0,000 0,01875849 0,08796919 GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0006241|CTP biosynthetic process, ! Golgi to endosome transport GO:0006895 5 5 0,000 0,01875849 0,08774592 ! GTP metabolic process GO:0046039 5 5 0,000 0,01875849 0,08752377 ! establishment of tissue polarity GO:0007164 5 5 0,000 0,01875849 0,08730275 ! positive regulation of cell-cell adhesion GO:0022409 5 5 0,000 0,01875849 0,08708285 ! regulation of neurotransmitter secretion GO:0046928 5 5 0,000 0,01875849 0,08686405 GO:0001956|positive regulation of neurotransmitter secretion, ! neurotransmitter uptake GO:0001504 5 5 0,000 0,01875849 0,08664634 ! social behavior GO:0035176 5 5 0,000 0,01875849 0,08642973 ! macrophage chemotaxis GO:0048246 6 5 0,000 0,01875849 0,08621419 ! 2-oxoglutarate metabolic process GO:0006103 5 5 0,000 0,01875849 0,08599973 ! memory GO:0007613 5 5 0,000 0,01875849 0,08578633 ! dopamine receptor signaling pathway GO:0007212 5 5 0,000 0,01875849 0,08557399 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 5 5 0,000 0,01875849 0,08536269 ! membrane hyperpolarization GO:0060081 5 5 0,000 0,01875849 0,08515244 ! response to lipid GO:0033993 5 5 0,000 0,01875849 0,08494322 ! erythrocyte maturation GO:0043249 5 5 0,000 0,01875849 0,08473503 ! hippocampus development GO:0021766 6 5 0,000 0,01875849 0,08452785 ! regulation of carbohydrate biosynthetic process GO:0043255 5 5 0,000 0,01875849 0,08432168 ! glucocorticoid metabolic process GO:0008211 5 5 0,000 0,01875849 0,08411652 ! middle ear morphogenesis GO:0042474 5 5 0,000 0,01875849 0,08391236 ! amyloid precursor protein catabolic process GO:0042987 5 5 0,000 0,01875849 0,08370918 ! mechanosensory behavior GO:0007638 5 5 0,000 0,01875849 0,08350698 ! heart looping GO:0001947 5 5 0,000 0,01875849 0,08330576 ! negative regulation of endocytosis GO:0045806 5 5 0,000 0,01875849 0,08310551 ! response to interferon-gamma GO:0034341 5 5 0,000 0,01875849 0,08290621 ! pseudouridine synthesis GO:0001522 5 5 0,000 0,01875849 0,08270787 ! endocrine pancreas development GO:0031018 5 5 0,000 0,01875849 0,08251048 ! pH reduction GO:0045851 5 5 0,000 0,01875849 0,08231403 GO:0051452|intracellular pH reduction, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 5 5 0,000 0,01875849 0,0821185 ! lipopolysaccharide metabolic process GO:0008653 5 5 0,000 0,01875849 0,08192391 ! positive regulation of chemokine biosynthetic process GO:0045080 5 5 0,000 0,01875849 0,08173024 ! sphingoid biosynthetic process GO:0046520 5 5 0,000 0,01875849 0,08153748 GO:0046513|ceramide biosynthetic process, ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 5 5 0,000 0,01875849 0,08134562 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! thymic T cell selection GO:0045061 5 5 0,000 0,01875849 0,08115467 ! insulin-like growth factor receptor signaling pathway GO:0048009 5 5 0,000 0,01875849 0,08096461 ! photoreceptor cell maintenance GO:0045494 5 5 0,000 0,01875849 0,08077545 ! adrenal gland development GO:0030325 5 5 0,000 0,01875849 0,08058716 ! regulation of cardiac muscle hypertrophy GO:0010611 5 5 0,000 0,01875849 0,08039975 GO:0010612|regulation of cardiac muscle adaptation, GO:0014743|regulation of muscle hypertrophy, GO:0043502|regulation of muscle adaptation, ! melanocyte differentiation GO:0030318 5 5 0,000 0,01875849 0,0802132 GO:0050931|pigment cell differentiation, ! ovulation GO:0030728 5 5 0,000 0,01875849 0,08002752 ! astrocyte differentiation GO:0048708 5 5 0,000 0,01875849 0,0798427 ! mitochondrial respiratory chain complex assembly GO:0033108 5 5 0,000 0,01875849 0,07965873 GO:0032981|mitochondrial respiratory chain complex I assembly, GO:0010257|NADH dehydrogenase complex assembly, ! pituitary gland development GO:0021983 5 5 0,000 0,01875849 0,07947561 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 5 5 0,000 0,01875849 0,07929333 GO:0033135|regulation of peptidyl-serine phosphorylation, ! tyrosine metabolic process GO:0006570 5 5 0,000 0,01875849 0,07911188 ! cytoskeletal anchoring at plasma membrane GO:0007016 6 5 0,000 0,01875849 0,07893126 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 5 5 0,000 0,01875849 0,07875146 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, GO:0009164|nucleoside catabolic process, ! microtubule nucleation GO:0007020 5 5 0,000 0,01875849 0,07857248 ! regulation of interleukin-6 biosynthetic process GO:0045408 5 5 0,000 0,01875849 0,07839431 ! regulation of interleukin-8 biosynthetic process GO:0045414 5 5 0,000 0,01875849 0,07821695 ! indolalkylamine metabolic process GO:0006586 5 5 0,000 0,01875849 0,07804038 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! muscle cell migration GO:0014812 5 5 0,000 0,01875849 0,07786462 ! phasic smooth muscle contraction GO:0014821 5 5 0,000 0,01875849 0,07768964 ! central nervous system neuron axonogenesis GO:0021955 6 5 0,000 0,01875849 0,07751545 GO:0021952|central nervous system projection neuron axonogenesis, ! sister chromatid cohesion GO:0007062 5 5 0,000 0,01875849 0,07734204 ! response to ATP GO:0033198 5 5 0,000 0,01875849 0,0771694 ! regulation of type I interferon production GO:0032479 5 5 0,000 0,01875849 0,07699753 ! regulation of appetite GO:0032098 5 5 0,000 0,01875849 0,07682642 GO:0032095|regulation of response to food, ! vesicle fusion GO:0006906 5 5 0,000 0,01875849 0,07665608 ! paraxial mesoderm development GO:0048339 5 5 0,000 0,01875849 0,07648648 ! regulation of the force of heart contraction GO:0002026 5 5 0,000 0,01875849 0,07631764 ! maintenance of protein location in nucleus GO:0051457 5 5 0,000 0,01875849 0,07614954 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,01875849 0,07598218 ! receptor clustering GO:0043113 5 5 0,000 0,01875849 0,07581555 ! neurotransmitter biosynthetic process GO:0042136 6 5 0,000 0,01875849 0,07564965 ! fear response GO:0042596 5 5 0,000 0,01875849 0,07548448 ! actin cytoskeleton reorganization GO:0031532 5 5 0,000 0,01875849 0,07532002 ! lens development in camera-type eye GO:0002088 5 5 0,000 0,01875849 0,07515628 ! retinol metabolic process GO:0042572 5 5 0,000 0,01875849 0,07499325 ! corticosteroid receptor signaling pathway GO:0031958 5 5 0,000 0,01875849 0,07483093 GO:0042921|glucocorticoid receptor signaling pathway, ! temperature homeostasis GO:0001659 5 5 0,000 0,01875849 0,07466931 ! positive regulation of exocytosis GO:0045921 6 5 0,000 0,01875849 0,07450838 ! parturition GO:0007567 5 5 0,000 0,01875849 0,07434815 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,01875849 0,07418861 ! regulation of vascular endothelial growth factor production GO:0010574 5 5 0,000 0,01875849 0,07402974 ! Schwann cell differentiation GO:0014037 5 5 0,000 0,01875849 0,07387156 ! acyl-CoA metabolic process GO:0006637 5 5 0,000 0,01875849 0,07371405 ! wound healing, spreading of epidermal cells GO:0035313 5 5 0,000 0,01875849 0,07355721 ! regulation of gliogenesis GO:0014013 5 5 0,000 0,01875849 0,07340104 GO:0045685|regulation of glial cell differentiation, ! positive regulation of peptide secretion GO:0002793 5 5 0,000 0,01875849 0,07324553 ! response to UV-B GO:0010224 5 5 0,000 0,01875849 0,07309068 ! oligodendrocyte development GO:0014003 5 5 0,000 0,01875849 0,07293648 ! hyaluronan metabolic process GO:0030212 5 5 0,000 0,01875849 0,07278293 ! activated T cell proliferation GO:0050798 5 5 0,000 0,01875849 0,07263002 ! interaction with symbiont GO:0051702 5 5 0,000 0,01875849 0,07247776 ! cellular extravasation GO:0045123 5 5 0,000 0,01875849 0,07232613 ! positive regulation of axonogenesis GO:0050772 5 5 0,000 0,01875849 0,07217514 ! peptidyl-asparagine modification GO:0018196 5 5 0,000 0,01875849 0,07202477 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! positive regulation of phagocytosis GO:0050766 5 5 0,000 0,01875849 0,07187503 ! regulation of insulin receptor signaling pathway GO:0046626 5 5 0,000 0,01875849 0,07172591 ! antigen processing and presentation of exogenous antigen GO:0019884 5 5 0,000 0,01875849 0,07157741 ! enucleate erythrocyte differentiation GO:0043353 6 5 0,000 0,01875849 0,07142953 ! response to amine stimulus GO:0014075 5 5 0,000 0,01875849 0,07128225 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 5 5 0,000 0,01875849 0,07113558 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 5 5 0,000 0,01875849 0,07098951 ! synaptic vesicle exocytosis GO:0016079 6 5 0,000 0,01875849 0,07084404 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 5 5 0,000 0,01875849 0,07069916 ! glycosylceramide metabolic process GO:0006677 5 5 0,000 0,01875849 0,07055488 ! neuron recognition GO:0008038 5 5 0,000 0,01875849 0,07041118 ! decidualization GO:0046697 5 5 0,000 0,01875849 0,07026807 ! hair follicle maturation GO:0048820 5 5 0,000 0,01875849 0,07012554 ! phosphatidylinositol biosynthetic process GO:0006661 5 5 0,000 0,01875849 0,06998358 ! regulation of mitochondrial membrane potential GO:0051881 5 5 0,000 0,01875849 0,0698422 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 0,01875849 0,06970139 GO:0009155|purine deoxyribonucleotide catabolic process, ! regulation of interleukin-12 production GO:0032655 5 5 0,000 0,01875849 0,06956115 ! positive regulation of interleukin-6 production GO:0032755 5 5 0,000 0,01875849 0,06942147 ! positive regulation of monooxygenase activity GO:0032770 5 5 0,000 0,01875849 0,06928235 ! postreplication repair GO:0006301 5 5 0,000 0,01875849 0,06914378 ! cellular pigmentation GO:0033059 5 5 0,000 0,01875849 0,06900577 ! histone methylation GO:0016571 5 5 0,000 0,01875849 0,06886831 ! DNA methylation GO:0006306 5 5 0,000 0,01875849 0,06873139 GO:0006305|DNA alkylation, ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,01875849 0,06859502 ! positive regulation of immunoglobulin mediated immune response GO:0002891 5 5 0,000 0,01875849 0,06845919 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of interferon-gamma production GO:0032729 5 5 0,000 0,01875849 0,06832389 ! negative regulation of tumor necrosis factor production GO:0032720 5 5 0,000 0,01875849 0,06818913 ! intracellular cholesterol transport GO:0032367 5 5 0,000 0,01875849 0,0680549 GO:0032366|intracellular sterol transport, ! regulation of mast cell activation GO:0033003 5 5 0,000 0,01875849 0,0679212 ! morphogenesis of a polarized epithelium GO:0001738 5 5 0,000 0,01875849 0,06778802 ! regulation of hormone metabolic process GO:0032350 5 5 0,000 0,01875849 0,06765536 ! regulation of transcription from RNA polymerase III promoter GO:0006359 5 5 0,000 0,01875849 0,06752322 ! regulation of inflammatory response to antigenic stimulus GO:0002861 5 5 0,000 0,01875849 0,0673916 ! sterol catabolic process GO:0016127 5 5 0,000 0,01875849 0,06726049 GO:0006707|cholesterol catabolic process, ! negative regulation of oxidoreductase activity GO:0051354 5 5 0,000 0,01875849 0,06712988 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 5 5 0,000 0,01875849 0,06699979 ! detection of biotic stimulus GO:0009595 5 5 0,000 0,01875849 0,06687019 ! regulation of immune response to tumor cell GO:0002837 5 5 0,000 0,01875849 0,0667411 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 5 5 0,000 0,01875849 0,06661251 ! positive regulation of interleukin-1 beta secretion GO:0050718 5 5 0,000 0,01875849 0,0664844 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 5 5 0,000 0,01875849 0,0663568 GO:0002820|negative regulation of adaptive immune response, ! cellular response to nutrient GO:0031670 5 5 0,000 0,01875849 0,06622968 ! peptidyl-lysine modification GO:0018205 5 5 0,000 0,01875849 0,06610304 ! peptidyl-histidine modification GO:0018202 5 5 0,000 0,01875849 0,06597689 ! nucleosome positioning GO:0016584 5 5 0,000 0,01875849 0,06585122 ! regulation of isotype switching GO:0045191 5 5 0,000 0,01875849 0,06572603 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 5 5 0,000 0,01875849 0,06560131 ! negative regulation of neurological system process GO:0031645 5 5 0,000 0,01875849 0,06547707 ! regulation of myoblast differentiation GO:0045661 5 5 0,000 0,01875849 0,06535329 ! glutathione biosynthetic process GO:0006750 5 5 0,000 0,01875849 0,06522998 ! NADPH regeneration GO:0006740 5 5 0,000 0,01875849 0,06510714 GO:0006098|pentose-phosphate shunt, ! positive regulation of erythrocyte differentiation GO:0045648 5 5 0,000 0,01875849 0,06498476 ! positive regulation of epidermis development GO:0045684 5 5 0,000 0,01875849 0,06486283 ! positive regulation of leukocyte chemotaxis GO:0002690 5 5 0,000 0,01875849 0,06474137 GO:0002688|regulation of leukocyte chemotaxis, ! musculoskeletal movement GO:0050881 5 5 0,000 0,01875849 0,06462036 GO:0050879|multicellular organismal movement, ! neuromuscular process controlling posture GO:0050884 5 5 0,000 0,01875849 0,0644998 ! sarcomere organization GO:0045214 5 5 0,000 0,01875849 0,06437968 ! regulation of epidermal cell differentiation GO:0045604 5 5 0,000 0,01875849 0,06426002 ! activation of NF-kappaB-inducing kinase activity GO:0007250 5 5 0,000 0,01875849 0,0641408 ! negative regulation of glucose transport GO:0010829 5 5 0,000 0,01875849 0,06402202 GO:0046325|negative regulation of glucose import, ! positive regulation of T-helper cell differentiation GO:0045624 5 5 0,000 0,01875849 0,06390368 GO:0045622|regulation of T-helper cell differentiation, ! oocyte differentiation GO:0009994 5 5 0,000 0,01875849 0,06378578 GO:0048599|oocyte development, ! dopamine biosynthetic process GO:0042416 5 5 0,000 0,01875849 0,06366831 ! regulation of protein homodimerization activity GO:0043496 6 5 0,000 0,01875849 0,06355127 ! spleen development GO:0048536 5 5 0,000 0,01875849 0,06343466 ! male genitalia development GO:0030539 5 5 0,000 0,01875849 0,06331848 ! nicotinamide nucleotide biosynthetic process GO:0019359 5 5 0,000 0,01875849 0,06320272 ! quaternary ammonium group transport GO:0015697 5 5 0,000 0,01875849 0,06308739 ! thyroid hormone metabolic process GO:0042403 5 5 0,000 0,01875849 0,06297248 ! leukocyte mediated cytotoxicity GO:0001909 5 5 0,000 0,01875849 0,06285798 ! positive regulation of viral reproduction GO:0048524 5 5 0,000 0,01875849 0,0627439 ! removal of superoxide radicals GO:0019430 6 5 0,000 0,01875849 0,06263024 ! myeloid cell homeostasis GO:0002262 5 5 0,000 0,01875849 0,06251698 ! regulation of fatty acid oxidation GO:0046320 5 5 0,000 0,01875849 0,06240413 ! regulation of Rac protein signal transduction GO:0035020 5 5 0,000 0,01875849 0,06229169 ! ATP catabolic process GO:0006200 5 5 0,000 0,01875849 0,06217966 ! lymphocyte activation during immune response GO:0002285 5 5 0,000 0,01875849 0,06206803 ! blastocyst formation GO:0001825 5 5 0,000 0,01875849 0,06195679 ! regulation of fibrinolysis GO:0051917 5 5 0,000 0,01875849 0,06184596 ! negative regulation of organic acid transport GO:0032891 5 5 0,000 0,01875849 0,06173552 ! pyrimidine base metabolic process GO:0006206 5 5 0,000 0,01875849 0,06162547 ! activation of innate immune response GO:0002218 5 5 0,000 0,01875849 0,06151582 GO:0002758|innate immune response-activating signal transduction, ! catecholamine transport GO:0051937 5 5 0,000 0,01875849 0,06140656 ! negative regulation of blood vessel endothelial cell migration GO:0043537 5 5 0,000 0,01875849 0,06129768 ! regulation of NF-kappaB import into nucleus GO:0042345 5 5 0,000 0,01875849 0,06118919 ! muscle adaptation GO:0043500 5 5 0,000 0,01875849 0,06108108 ! positive regulation of actin filament bundle formation GO:0032233 5 5 0,000 0,01875849 0,06097335 ! embryonic heart tube development GO:0035050 5 5 0,000 0,01875849 0,060866 ! cardiac cell differentiation GO:0035051 6 5 0,000 0,01875849 0,06075903 ! positive regulation of homeostatic process GO:0032846 5 5 0,000 0,01875849 0,06065244 ! defense response to fungus GO:0050832 5 5 0,000 0,01875849 0,06054622 ! lysogeny GO:0030069 5 5 0,000 0,01875849 0,06044037 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 5 5 0,000 0,01875849 0,06033489 ! B cell receptor signaling pathway GO:0050853 5 5 0,000 0,01875849 0,06022977 ! positive regulation of smooth muscle contraction GO:0045987 5 5 0,000 0,01875849 0,06012503 ! response to nicotine GO:0035094 5 5 0,000 0,01875849 0,06002064 ! establishment of cell polarity GO:0030010 5 5 0,000 0,01875849 0,05991662 ! mitochondrion localization GO:0051646 5 5 0,000 0,01875849 0,05981296 ! nucleus localization GO:0051647 5 5 0,000 0,01875849 0,05970966 ! regulation of synapse structure and activity GO:0050803 5 5 0,000 0,01875849 0,05960671 ! protein polymerization GO:0051258 65 60 1,000 0,02125309 0,06741729 ! regulation of protein amino acid phosphorylation GO:0001932 62 61 1,000 0,02192298 0,06942277 ! carboxylic acid catabolic process GO:0046395 63 61 1,000 0,02192298 0,0693037 GO:0016054|organic acid catabolic process, ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 6 6 0,000 0,02246936 0,07090931 ! axon extension GO:0048675 7 6 0,000 0,02246936 0,0707881 ! oligosaccharide biosynthetic process GO:0009312 6 6 0,000 0,02246936 0,0706673 ! tRNA modification GO:0006400 6 6 0,000 0,02246936 0,07054691 ! somatic diversification of immune receptors via somatic mutation GO:0002566 6 6 0,000 0,02246936 0,07042693 GO:0016446|somatic hypermutation of immunoglobulin genes, ! 'de novo' posttranslational protein folding GO:0051084 6 6 0,000 0,02246936 0,07030736 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 6 6 0,000 0,02246936 0,0701882 ! negative regulation of cellular catabolic process GO:0031330 6 6 0,000 0,02246936 0,07006944 ! regulation of S phase GO:0033261 6 6 0,000 0,02246936 0,06995108 ! myotube differentiation GO:0014902 6 6 0,000 0,02246936 0,06983311 ! regulation of B cell proliferation GO:0030888 6 6 0,000 0,02246936 0,06971555 ! bone remodeling GO:0046849 6 6 0,000 0,02246936 0,06959838 ! N-glycan processing GO:0006491 6 6 0,000 0,02246936 0,06948161 ! regulation of lipid kinase activity GO:0043550 6 6 0,000 0,02246936 0,06936522 ! glycosaminoglycan catabolic process GO:0006027 6 6 0,000 0,02246936 0,06924923 ! negative regulation of JAK-STAT cascade GO:0046426 6 6 0,000 0,02246936 0,06913362 ! retina development in camera-type eye GO:0060041 6 6 0,000 0,02246936 0,06901839 ! RNA methylation GO:0001510 6 6 0,000 0,02246936 0,06890356 ! cartilage condensation GO:0001502 7 6 0,000 0,02246936 0,0687891 ! regulation of activated T cell proliferation GO:0046006 6 6 0,000 0,02246936 0,06867502 ! succinate metabolic process GO:0006105 7 6 0,000 0,02246936 0,06856132 ! artery development GO:0060840 6 6 0,000 0,02246936 0,06844799 GO:0048844|artery morphogenesis, ! positive regulation of neurotransmitter transport GO:0051590 6 6 0,000 0,02246936 0,06833504 ! bile acid metabolic process GO:0008206 6 6 0,000 0,02246936 0,06822247 ! androgen metabolic process GO:0008209 6 6 0,000 0,02246936 0,06811026 ! estrogen metabolic process GO:0008210 6 6 0,000 0,02246936 0,06799842 ! limbic system development GO:0021761 7 6 0,000 0,02246936 0,06788695 ! cytoplasmic sequestering of transcription factor GO:0042994 6 6 0,000 0,02246936 0,06777584 ! positive regulation of transcription factor import into nucleus GO:0042993 6 6 0,000 0,02246936 0,06766509 ! positive regulation of heart contraction GO:0045823 6 6 0,000 0,02246936 0,06755471 ! positive regulation of gene expression, epigenetic GO:0045815 6 6 0,000 0,02246936 0,06744469 ! pathogenesis GO:0009405 6 6 0,000 0,02246936 0,06733502 ! negative regulation of protein amino acid phosphorylation GO:0001933 6 6 0,000 0,02246936 0,06722571 ! positive regulation of cell growth GO:0030307 6 6 0,000 0,02246936 0,06711675 ! ribonucleoside triphosphate catabolic process GO:0009203 6 6 0,000 0,02246936 0,06700815 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! regulation of chemokine biosynthetic process GO:0045073 6 6 0,000 0,02246936 0,0668999 ! nerve growth factor receptor signaling pathway GO:0048011 6 6 0,000 0,02246936 0,06679199 ! inositol phosphate-mediated signaling GO:0048016 6 6 0,000 0,02246936 0,06668444 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 6 6 0,000 0,02246936 0,06657723 ! arginine metabolic process GO:0006525 6 6 0,000 0,02246936 0,06647036 GO:0006527|arginine catabolic process, ! regulation of catecholamine secretion GO:0050433 6 6 0,000 0,02246936 0,06636384 ! oligodendrocyte differentiation GO:0048709 6 6 0,000 0,02246936 0,06625766 ! glutamate catabolic process GO:0006538 7 6 0,000 0,02246936 0,06615182 ! telomere maintenance via telomerase GO:0007004 6 6 0,000 0,02246936 0,06604631 GO:0010833|telomere maintenance via telomere lengthening, ! L-phenylalanine metabolic process GO:0006558 6 6 0,000 0,02246936 0,06594114 GO:0006559|L-phenylalanine catabolic process, ! glucan biosynthetic process GO:0009250 6 6 0,000 0,02246936 0,06583631 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 6 6 0,000 0,02246936 0,0657318 ! V(D)J recombination GO:0033151 6 6 0,000 0,02246936 0,06562763 ! focal adhesion formation GO:0048041 7 6 0,000 0,02246936 0,06552379 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 0,02246936 0,06542028 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 6 6 0,000 0,02246936 0,06531709 ! negative regulation of endothelial cell migration GO:0010596 6 6 0,000 0,02246936 0,06521423 ! regulation of heart rate GO:0002027 6 6 0,000 0,02246936 0,06511169 ! lipid digestion GO:0044241 6 6 0,000 0,02246936 0,06500948 ! asymmetric protein localization GO:0008105 6 6 0,000 0,02246936 0,06490758 ! retrograde transport, endosome to Golgi GO:0042147 6 6 0,000 0,02246936 0,064806 ! phagocytosis, engulfment GO:0006911 6 6 0,000 0,02246936 0,06470475 ! Rac protein signal transduction GO:0016601 6 6 0,000 0,02246936 0,0646038 ! regulation of calcium ion transport into cytosol GO:0010522 6 6 0,000 0,02246936 0,06450317 ! ruffle organization GO:0031529 6 6 0,000 0,02246936 0,06440286 ! preassembly of GPI anchor in ER membrane GO:0016254 6 6 0,000 0,02246936 0,06430285 ! retinoic acid metabolic process GO:0042573 6 6 0,000 0,02246936 0,06420316 ! neutral amino acid transport GO:0015804 6 6 0,000 0,02246936 0,06410377 ! L-amino acid transport GO:0015807 6 6 0,000 0,02246936 0,06400469 ! bone mineralization GO:0030282 6 6 0,000 0,02246936 0,06390592 GO:0031214|biomineral formation, ! rRNA modification GO:0000154 6 6 0,000 0,02246936 0,06380745 ! negative regulation of ossification GO:0030279 6 6 0,000 0,02246936 0,06370929 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 6 6 0,000 0,02246936 0,06361142 GO:0002717|positive regulation of natural killer cell mediated immunity, GO:0002715|regulation of natural killer cell mediated immunity, GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 7 6 0,000 0,02246936 0,06351386 ! purine base biosynthetic process GO:0009113 6 6 0,000 0,02246936 0,0634166 ! negative regulation of axonogenesis GO:0050771 7 6 0,000 0,02246936 0,06331963 ! regulation of phagocytosis GO:0050764 6 6 0,000 0,02246936 0,06322296 ! regulation of organ growth GO:0046620 6 6 0,000 0,02246936 0,06312658 ! regulation of circadian rhythm GO:0042752 6 6 0,000 0,02246936 0,0630305 ! positive regulation of T cell mediated immunity GO:0002711 6 6 0,000 0,02246936 0,06293471 ! response to dsRNA GO:0043331 6 6 0,000 0,02246936 0,06283921 ! DNA unwinding during replication GO:0006268 6 6 0,000 0,02246936 0,062744 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 6 6 0,000 0,02246936 0,06264907 GO:0009147|pyrimidine nucleoside triphosphate metabolic process, ! genitalia development GO:0048806 6 6 0,000 0,02246936 0,06255444 ! sphingomyelin metabolic process GO:0006684 6 6 0,000 0,02246936 0,06246009 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 6 6 0,000 0,02246936 0,06236602 ! positive regulation of B cell differentiation GO:0045579 6 6 0,000 0,02246936 0,06227224 ! multicellular organismal aging GO:0010259 6 6 0,000 0,02246936 0,06217873 ! respiratory chain complex IV assembly GO:0008535 6 6 0,000 0,02246936 0,06208551 ! erythrocyte development GO:0048821 6 6 0,000 0,02246936 0,06199257 ! renal water homeostasis GO:0003091 6 6 0,000 0,02246936 0,06189991 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 6 6 0,000 0,02246936 0,06180752 GO:0043372|positive regulation of CD4-positive, alpha beta T cell differentiation, ! ribosomal large subunit biogenesis GO:0042273 6 6 0,000 0,02246936 0,06171541 ! regulation of Rho GTPase activity GO:0032319 6 6 0,000 0,02246936 0,06162357 ! ribosome assembly GO:0042255 6 6 0,000 0,02246936 0,061532 ! positive regulation of Ras GTPase activity GO:0032320 6 6 0,000 0,02246936 0,06144071 ! diencephalon development GO:0021536 6 6 0,000 0,02246936 0,06134968 ! fucose catabolic process GO:0019317 6 6 0,000 0,02246936 0,06125893 GO:0042355|L-fucose catabolic process, ! nitric oxide metabolic process GO:0046209 6 6 0,000 0,02246936 0,06116844 GO:0006809|nitric oxide biosynthetic process, ! protein sumoylation GO:0016925 6 6 0,000 0,02246936 0,06107823 ! regulation of lipid transport GO:0032368 6 6 0,000 0,02246936 0,06098827 ! regulation of cell division GO:0051302 6 6 0,000 0,02246936 0,06089858 ! positive regulation of interleukin-1 secretion GO:0050716 6 6 0,000 0,02246936 0,06080916 ! cellular metabolic compound salvage GO:0043094 6 6 0,000 0,02246936 0,06072 ! regulation of T-helper 2 type immune response GO:0002828 6 6 0,000 0,02246936 0,06063109 ! salivary gland morphogenesis GO:0007435 6 6 0,000 0,02246936 0,06054245 ! neuroblast proliferation GO:0007405 6 6 0,000 0,02246936 0,06045407 ! regulation of interleukin-1 beta secretion GO:0050706 6 6 0,000 0,02246936 0,06036594 ! nitric oxide mediated signal transduction GO:0007263 6 6 0,000 0,02246936 0,06027807 ! regulation of glucose transport GO:0010827 6 6 0,000 0,02246936 0,06019046 GO:0046324|regulation of glucose import, ! intestinal absorption GO:0050892 6 6 0,000 0,02246936 0,0601031 ! methionine biosynthetic process GO:0009086 6 6 0,000 0,02246936 0,060016 ! glutamine family amino acid biosynthetic process GO:0009084 6 6 0,000 0,02246936 0,05992914 ! serine family amino acid biosynthetic process GO:0009070 6 6 0,000 0,02246936 0,05984254 ! thymus development GO:0048538 6 6 0,000 0,02246936 0,05975619 ! lymph node development GO:0048535 6 6 0,000 0,02246936 0,05967008 ! organic cation transport GO:0015695 6 6 0,000 0,02246936 0,05958423 ! negative regulation of BMP signaling pathway GO:0030514 6 6 0,000 0,02246936 0,05949862 ! regulation of RNA splicing GO:0043484 6 6 0,000 0,02246936 0,05941325 ! positive regulation of JNK cascade GO:0046330 7 6 0,000 0,02246936 0,05932813 ! sperm-egg recognition GO:0035036 7 6 0,000 0,02246936 0,05924326 GO:0007339|binding of sperm to zona pellucida, ! germ cell migration GO:0008354 6 6 0,000 0,02246936 0,05915862 ! establishment or maintenance of apical/basal cell polarity GO:0035088 6 6 0,000 0,02246936 0,05907423 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 6 6 0,000 0,02246936 0,05899008 ! alditol metabolic process GO:0019400 6 6 0,000 0,02246936 0,05890617 ! regulation of synaptic transmission, GABAergic GO:0032228 6 6 0,000 0,02246936 0,0588225 ! regulation of amino acid transport GO:0051955 6 6 0,000 0,02246936 0,05873906 ! maternal placenta development GO:0001893 6 6 0,000 0,02246936 0,05865586 ! negative regulation of immune effector process GO:0002698 6 6 0,000 0,02246936 0,0585729 ! morphogenesis of an epithelium GO:0002009 63 62 1,000 0,02260164 0,0588345 GO:0060429|epithelium development, ! axonogenesis GO:0007409 66 62 1,000 0,02260164 0,05875151 ! regulation of cellular component biogenesis GO:0044087 63 62 1,000 0,02260164 0,05866876 ! regulation of lymphocyte activation GO:0051249 62 62 1,000 0,02260164 0,05858625 ! negative regulation of cellular component organization GO:0051129 65 63 1,000 0,023289 0,06028318 ! glucose metabolic process GO:0006006 63 63 1,000 0,023289 0,06019863 ! regulation of response to external stimulus GO:0032101 65 64 1,000 0,02398498 0,06191081 ! positive regulation of protein metabolic process GO:0051247 64 64 1,000 0,02398498 0,06182422 ! polysaccharide metabolic process GO:0005976 69 66 1,000 0,02540255 0,06538674 ! cell morphogenesis involved in neuron differentiation GO:0048667 72 67 1,000 0,026124 0,06714998 GO:0048812|neuron projection morphogenesis, GO:0048858|cell projection morphogenesis, ! striated muscle tissue development GO:0014706 69 67 1,000 0,026124 0,06705646 ! respiratory burst GO:0045730 7 7 0,000 0,02616674 0,06707275 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 7 7 0,000 0,02616674 0,0669796 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 7 7 0,000 0,02616674 0,0668867 ! negative regulation of cell projection organization GO:0031345 8 7 0,000 0,02616674 0,06679406 ! positive regulation of blood pressure GO:0045777 7 7 0,000 0,02616674 0,06670167 ! pteridine and derivative biosynthetic process GO:0042559 7 7 0,000 0,02616674 0,06660954 ! regulation of chemokine production GO:0032642 7 7 0,000 0,02616674 0,06651767 ! double-strand break repair via homologous recombination GO:0000724 7 7 0,000 0,02616674 0,06642605 GO:0000725|recombinational repair, ! positive regulation of GTPase activity GO:0043547 7 7 0,000 0,02616674 0,06633468 ! SMAD protein nuclear translocation GO:0007184 7 7 0,000 0,02616674 0,06624356 ! cellular protein complex disassembly GO:0043624 8 7 0,000 0,02616674 0,06615269 GO:0043241|protein complex disassembly, ! hair follicle morphogenesis GO:0031069 7 7 0,000 0,02616674 0,06606207 ! gene silencing by RNA GO:0031047 7 7 0,000 0,02616674 0,0659717 ! regulation of receptor-mediated endocytosis GO:0048259 7 7 0,000 0,02616674 0,06588157 ! oxaloacetate metabolic process GO:0006107 7 7 0,000 0,02616674 0,06579169 ! regulation of neurotransmitter transport GO:0051588 7 7 0,000 0,02616674 0,06570206 ! keratinocyte proliferation GO:0043616 7 7 0,000 0,02616674 0,06561267 ! axis specification GO:0009798 7 7 0,000 0,02616674 0,06552352 ! negative regulation of muscle cell differentiation GO:0051148 7 7 0,000 0,02616674 0,06543461 ! visual behavior GO:0007632 7 7 0,000 0,02616674 0,06534595 GO:0008542|visual learning, ! startle response GO:0001964 7 7 0,000 0,02616674 0,06525752 ! amyloid precursor protein metabolic process GO:0042982 7 7 0,000 0,02616674 0,06516934 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 8 7 0,000 0,02616674 0,06508139 ! positive regulation of lipid metabolic process GO:0045834 7 7 0,000 0,02616674 0,06499368 ! negative regulation of lipid metabolic process GO:0045833 7 7 0,000 0,02616674 0,0649062 ! regulation of interferon-gamma biosynthetic process GO:0045072 7 7 0,000 0,02616674 0,06481896 ! endothelial cell differentiation GO:0045446 7 7 0,000 0,02616674 0,06473196 ! negative regulation of striated muscle development GO:0045843 7 7 0,000 0,02616674 0,06464519 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 7 7 0,000 0,02616674 0,06455865 ! hemoglobin metabolic process GO:0020027 7 7 0,000 0,02616674 0,06447234 ! regulation of exit from mitosis GO:0007096 7 7 0,000 0,02616674 0,06438626 ! protein targeting to ER GO:0045047 8 7 0,000 0,02616674 0,06430041 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 7 7 0,000 0,02616674 0,06421479 ! endoderm development GO:0007492 7 7 0,000 0,02616674 0,0641294 ! regulation of defense response to virus GO:0050688 7 7 0,000 0,02616674 0,06404424 ! glycolipid biosynthetic process GO:0009247 7 7 0,000 0,02616674 0,0639593 GO:0006688|glycosphingolipid biosynthetic process, ! response to hexose stimulus GO:0009746 7 7 0,000 0,02616674 0,06387458 GO:0034284|response to monosaccharide stimulus, GO:0009749|response to glucose stimulus, ! membrane protein ectodomain proteolysis GO:0006509 7 7 0,000 0,02616674 0,06379009 GO:0033619|membrane protein proteolysis, ! positive regulation of survival gene product expression GO:0045885 7 7 0,000 0,02616674 0,06370583 ! regulation of skeletal muscle fiber development GO:0048742 7 7 0,000 0,02616674 0,06362178 ! cardiac muscle tissue development GO:0048738 7 7 0,000 0,02616674 0,06353796 ! nucleotide-sugar metabolic process GO:0009225 7 7 0,000 0,02616674 0,06345436 ! complement activation, alternative pathway GO:0006957 7 7 0,000 0,02616674 0,06337097 ! arachidonic acid secretion GO:0050482 7 7 0,000 0,02616674 0,06328781 GO:0032309|icosanoid secretion, ! polyamine biosynthetic process GO:0006596 7 7 0,000 0,02616674 0,06320486 ! UV protection GO:0009650 7 7 0,000 0,02616674 0,06312213 ! DNA integration GO:0015074 7 7 0,000 0,02616674 0,06303962 ! myofibril assembly GO:0030239 7 7 0,000 0,02616674 0,06295732 GO:0055002|striated muscle cell development, ! positive regulation of muscle contraction GO:0045933 7 7 0,000 0,02616674 0,06287524 ! negative regulation of muscle contraction GO:0045932 7 7 0,000 0,02616674 0,06279337 ! chondroitin sulfate biosynthetic process GO:0030206 7 7 0,000 0,02616674 0,06271172 GO:0030204|chondroitin sulfate metabolic process, ! regulation of exocytosis GO:0017157 8 7 0,000 0,02616674 0,06263027 ! phosphatidylcholine biosynthetic process GO:0006656 7 7 0,000 0,02616674 0,06254904 ! heparan sulfate proteoglycan metabolic process GO:0030201 7 7 0,000 0,02616674 0,06246802 GO:0015012|heparan sulfate proteoglycan biosynthetic process, ! stem cell development GO:0048864 7 7 0,000 0,02616674 0,06238721 GO:0019827|stem cell maintenance, ! alpha-beta T cell differentiation GO:0046632 7 7 0,000 0,02616674 0,0623066 ! negative regulation of myeloid leukocyte differentiation GO:0002762 7 7 0,000 0,02616674 0,06222621 ! NLS-bearing substrate import into nucleus GO:0006607 7 7 0,000 0,02616674 0,06214602 ! axon cargo transport GO:0008088 7 7 0,000 0,02616674 0,06206604 ! eating behavior GO:0042755 7 7 0,000 0,02616674 0,06198626 ! RNA-dependent DNA replication GO:0006278 7 7 0,000 0,02616674 0,06190669 ! purine nucleoside triphosphate catabolic process GO:0009146 7 7 0,000 0,02616674 0,06182732 ! regulation of interleukin-8 production GO:0032677 7 7 0,000 0,02616674 0,06174816 ! purine ribonucleotide catabolic process GO:0009154 7 7 0,000 0,02616674 0,06166919 ! ribosomal small subunit biogenesis GO:0042274 7 7 0,000 0,02616674 0,06159043 ! protein import into peroxisome matrix GO:0016558 7 7 0,000 0,02616674 0,06151187 ! induction of an organ GO:0001759 7 7 0,000 0,02616674 0,06143352 ! leukocyte activation during immune response GO:0002366 7 7 0,000 0,02616674 0,06135536 GO:0002263|cell activation during immune response, ! response to estradiol stimulus GO:0032355 7 7 0,000 0,02616674 0,0612774 ! autonomic nervous system development GO:0048483 7 7 0,000 0,02616674 0,06119963 ! intracellular lipid transport GO:0032365 7 7 0,000 0,02616674 0,06112207 ! detection of chemical stimulus GO:0009593 8 7 0,000 0,02616674 0,0610447 ! platelet activation GO:0030168 8 7 0,000 0,02616674 0,06096752 ! negative regulation of cytokine secretion GO:0050710 7 7 0,000 0,02616674 0,06089054 ! regulation of interleukin-1 secretion GO:0050704 7 7 0,000 0,02616674 0,06081376 ! natural killer cell activation GO:0030101 7 7 0,000 0,02616674 0,06073717 ! NADP metabolic process GO:0006739 7 7 0,000 0,02616674 0,06066077 ! neuromuscular synaptic transmission GO:0007274 7 7 0,000 0,02616674 0,06058456 ! synaptic transmission, cholinergic GO:0007271 7 7 0,000 0,02616674 0,06050854 ! ubiquinone metabolic process GO:0006743 7 7 0,000 0,02616674 0,06043272 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, GO:0042375|quinone cofactor metabolic process, ! regulation of macrophage differentiation GO:0045649 8 7 0,000 0,02616674 0,06035708 ! positive regulation of acute inflammatory response GO:0002675 7 7 0,000 0,02616674 0,06028164 ! regulation of osteoclast differentiation GO:0045670 7 7 0,000 0,02616674 0,06020638 ! multicellular organismal water homeostasis GO:0050891 7 7 0,000 0,02616674 0,06013131 ! regulation of ATPase activity GO:0043462 7 7 0,000 0,02616674 0,06005643 ! cell-cell recognition GO:0009988 8 7 0,000 0,02616674 0,05998173 ! hormone catabolic process GO:0042447 7 7 0,000 0,02616674 0,05990722 ! dopamine metabolic process GO:0042417 7 7 0,000 0,02616674 0,05983289 ! cAMP biosynthetic process GO:0006171 7 7 0,000 0,02616674 0,05975875 ! oxygen transport GO:0015671 7 7 0,000 0,02616674 0,05968479 ! pyridine nucleotide biosynthetic process GO:0019363 7 7 0,000 0,02616674 0,05961101 ! biogenic amine catabolic process GO:0042402 7 7 0,000 0,02616674 0,05953742 ! regulation of axon extension GO:0030516 7 7 0,000 0,02616674 0,05946401 ! cell killing GO:0001906 7 7 0,000 0,02616674 0,05939078 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 7 7 0,000 0,02616674 0,05931772 ! adult feeding behavior GO:0008343 7 7 0,000 0,02616674 0,05924485 ! pyrimidine nucleotide catabolic process GO:0006244 7 7 0,000 0,02616674 0,05917216 ! positive regulation of protein polymerization GO:0032273 7 7 0,000 0,02616674 0,05909964 ! T cell receptor signaling pathway GO:0050852 7 7 0,000 0,02616674 0,05902731 ! response to cold GO:0009409 7 7 0,000 0,02616674 0,05895515 ! regulation of cell size GO:0008361 68 68 1,000 0,0268538 0,06042925 ! regionalization GO:0003002 70 69 1,000 0,02759189 0,06201445 ! response to nutrient levels GO:0031667 69 69 1,000 0,02759189 0,06193891 ! regulation of leukocyte activation GO:0002694 69 69 1,000 0,02759189 0,06186356 ! regulation of mitotic cell cycle GO:0007346 72 69 1,000 0,02759189 0,06178839 ! cell part morphogenesis GO:0032990 75 70 1,000 0,02833819 0,06338262 ! wound healing GO:0042060 74 70 1,000 0,02833819 0,06330579 ! growth GO:0040007 70 70 1,000 0,02833819 0,06322915 ! muscle tissue development GO:0060537 72 70 1,000 0,02833819 0,06315269 ! regulation of cell activation GO:0050865 71 71 1,000 0,02909263 0,0647557 ! regulation of skeletal muscle tissue development GO:0048641 8 8 0,000 0,02985068 0,06636284 ! negative regulation of muscle development GO:0048635 8 8 0,000 0,02985068 0,06628289 ! very-long-chain fatty acid metabolic process GO:0000038 8 8 0,000 0,02985068 0,06620312 ! positive regulation of translation GO:0045727 8 8 0,000 0,02985068 0,06612355 ! positive regulation of cell killing GO:0031343 8 8 0,000 0,02985068 0,06604417 ! superoxide anion generation GO:0042554 8 8 0,000 0,02985068 0,06596498 ! sulfur amino acid biosynthetic process GO:0000097 8 8 0,000 0,02985068 0,06588598 ! cGMP metabolic process GO:0046068 8 8 0,000 0,02985068 0,06580717 GO:0006182|cGMP biosynthetic process, ! thyroid gland development GO:0030878 8 8 0,000 0,02985068 0,06572855 ! 'de novo' protein folding GO:0006458 8 8 0,000 0,02985068 0,06565012 ! dicarboxylic acid transport GO:0006835 8 8 0,000 0,02985068 0,06557187 ! phosphoinositide phosphorylation GO:0046854 8 8 0,000 0,02985068 0,06549381 ! embryonic hindlimb morphogenesis GO:0035116 8 8 0,000 0,02985068 0,06541593 ! zinc ion transport GO:0006829 8 8 0,000 0,02985068 0,06533824 ! embryonic forelimb morphogenesis GO:0035115 8 8 0,000 0,02985068 0,06526073 ! folic acid and derivative biosynthetic process GO:0009396 8 8 0,000 0,02985068 0,06518341 ! regulation of neuronal synaptic plasticity GO:0048168 8 8 0,000 0,02985068 0,06510627 ! cardiac muscle contraction GO:0060048 8 8 0,000 0,02985068 0,06502931 ! lipid localization GO:0010876 8 8 0,000 0,02985068 0,06495253 GO:0019915|lipid storage, ! response to pain GO:0048265 8 8 0,000 0,02985068 0,06487594 ! response to cAMP GO:0051591 8 8 0,000 0,02985068 0,06479952 ! COPI coating of Golgi vesicle GO:0048205 8 8 0,000 0,02985068 0,06472329 GO:0048200|Golgi transport vesicle coating, ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 8 0,000 0,02985068 0,06464723 ! negative regulation of transcription factor import into nucleus GO:0042992 8 8 0,000 0,02985068 0,06457136 ! negative regulation of ion transport GO:0043271 8 8 0,000 0,02985068 0,06449566 ! regulation of response to extracellular stimulus GO:0032104 8 8 0,000 0,02985068 0,06442014 GO:0032107|regulation of response to nutrient levels, ! adult walking behavior GO:0007628 8 8 0,000 0,02985068 0,06434479 ! sensory perception of taste GO:0050909 8 8 0,000 0,02985068 0,06426962 ! organelle fusion GO:0048284 8 8 0,000 0,02985068 0,06419463 ! pancreas development GO:0031016 8 8 0,000 0,02985068 0,06411981 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 8 8 0,000 0,02985068 0,06404516 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! T cell selection GO:0045058 8 8 0,000 0,02985068 0,06397069 ! negative regulation of proteolysis GO:0045861 8 8 0,000 0,02985068 0,0638964 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 8 8 0,000 0,02985068 0,06382227 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 8 8 0,000 0,02985068 0,06374832 ! sperm motility GO:0030317 8 8 0,000 0,02985068 0,06367453 ! regulation of striated muscle contraction GO:0006942 8 8 0,000 0,02985068 0,06360092 ! DNA duplex unwinding GO:0032508 8 8 0,000 0,02985068 0,06352748 GO:0032392|DNA geometric change, ! glycine metabolic process GO:0006544 8 8 0,000 0,02985068 0,06345421 ! ribonucleotide catabolic process GO:0009261 8 8 0,000 0,02985068 0,0633811 ! negative regulation of microtubule depolymerization GO:0007026 8 8 0,000 0,02985068 0,06330817 GO:0031114|regulation of microtubule depolymerization, ! phosphagen metabolic process GO:0006599 8 8 0,000 0,02985068 0,0632354 GO:0006600|creatine metabolic process, ! polyamine metabolic process GO:0006595 8 8 0,000 0,02985068 0,0631628 ! Golgi organization GO:0007030 8 8 0,000 0,02985068 0,06309036 ! cell-cell junction assembly GO:0007043 8 8 0,000 0,02985068 0,06301809 ! regulation of stress fiber formation GO:0051492 9 8 0,000 0,02985068 0,06294599 ! fructose metabolic process GO:0006000 8 8 0,000 0,02985068 0,06287405 ! mannose metabolic process GO:0006013 9 8 0,000 0,02985068 0,06280228 ! NAD metabolic process GO:0019674 8 8 0,000 0,02985068 0,06273067 ! negative regulation of mitotic cell cycle GO:0045930 9 8 0,000 0,02985068 0,06265922 ! plasma membrane fusion GO:0045026 8 8 0,000 0,02985068 0,06258794 ! response to fungus GO:0009620 8 8 0,000 0,02985068 0,06251681 ! stem cell differentiation GO:0048863 8 8 0,000 0,02985068 0,06244585 ! alpha-beta T cell activation GO:0046631 8 8 0,000 0,02985068 0,06237505 ! positive regulation of myeloid leukocyte differentiation GO:0002763 9 8 0,000 0,02985068 0,06230441 ! embryonic digit morphogenesis GO:0042733 8 8 0,000 0,02985068 0,06223393 ! regulation of cytokine production during immune response GO:0002718 8 8 0,000 0,02985068 0,06216361 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 0,02985068 0,06209345 ! regulation of vasodilation GO:0042312 8 8 0,000 0,02985068 0,06202345 ! vasoconstriction GO:0042310 8 8 0,000 0,02985068 0,0619536 ! regulation of T cell mediated immunity GO:0002709 8 8 0,000 0,02985068 0,06188391 ! muscle cell development GO:0055001 8 8 0,000 0,02985068 0,06181438 ! nucleoside triphosphate catabolic process GO:0009143 8 8 0,000 0,02985068 0,061745 ! regulation of fatty acid metabolic process GO:0019217 8 8 0,000 0,02985068 0,06167578 ! sensory perception of pain GO:0019233 8 8 0,000 0,02985068 0,06160672 ! gastrulation with mouth forming second GO:0001702 8 8 0,000 0,02985068 0,0615378 ! immunoglobulin production during immune response GO:0002381 8 8 0,000 0,02985068 0,06146905 GO:0002208|somatic diversification of immunoglobulins during immune response, GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! mRNA cleavage GO:0006379 8 8 0,000 0,02985068 0,06140044 ! chromatin silencing GO:0006342 8 8 0,000 0,02985068 0,06133199 ! tissue regeneration GO:0042246 8 8 0,000 0,02985068 0,06126369 ! salivary gland development GO:0007431 8 8 0,000 0,02985068 0,06119555 ! negative regulation of blood coagulation GO:0030195 9 8 0,000 0,02985068 0,06112755 ! T cell homeostasis GO:0043029 8 8 0,000 0,02985068 0,06105971 ! peptide biosynthetic process GO:0043043 9 8 0,000 0,02985068 0,06099201 ! water homeostasis GO:0030104 8 8 0,000 0,02985068 0,06092447 ! cofactor transport GO:0051181 8 8 0,000 0,02985068 0,06085708 ! regulation of acute inflammatory response GO:0002673 8 8 0,000 0,02985068 0,06078983 ! acid secretion GO:0046717 8 8 0,000 0,02985068 0,06072273 ! C21-steroid hormone biosynthetic process GO:0006700 8 8 0,000 0,02985068 0,06065578 ! protein-chromophore linkage GO:0018298 9 8 0,000 0,02985068 0,06058898 ! regulation of immunoglobulin production GO:0002637 8 8 0,000 0,02985068 0,06052233 ! branched chain family amino acid metabolic process GO:0009081 8 8 0,000 0,02985068 0,06045582 ! catecholamine biosynthetic process GO:0042423 8 8 0,000 0,02985068 0,06038946 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 8 8 0,000 0,02985068 0,06032324 ! aromatic compound biosynthetic process GO:0019438 8 8 0,000 0,02985068 0,06025717 ! regulation of organic acid transport GO:0032890 8 8 0,000 0,02985068 0,06019124 ! positive regulation of calcium ion transport GO:0051928 8 8 0,000 0,02985068 0,06012546 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 8 8 0,000 0,02985068 0,06005982 ! regulation of multi-organism process GO:0043900 8 8 0,000 0,02985068 0,05999433 ! positive regulation of amine transport GO:0051954 8 8 0,000 0,02985068 0,05992897 ! developmental induction GO:0031128 8 8 0,000 0,02985068 0,05986376 GO:0045168|cell-cell signaling involved in cell fate specification, ! peptide hormone secretion GO:0030072 8 8 0,000 0,02985068 0,05979869 ! positive regulation of calcium-mediated signaling GO:0050850 8 8 0,000 0,02985068 0,05973376 ! actin filament polymerization GO:0030041 9 8 0,000 0,02985068 0,05966898 ! cytoplasmic sequestering of protein GO:0051220 8 8 0,000 0,02985068 0,05960433 ! peptide hormone processing GO:0016486 8 8 0,000 0,02985068 0,05953982 ! positive regulation of synaptic transmission GO:0050806 8 8 0,000 0,02985068 0,05947546 ! regulation of steroid biosynthetic process GO:0050810 8 8 0,000 0,02985068 0,05941123 ! sensory organ development GO:0007423 72 72 1,000 0,02985516 0,05935605 ! response to extracellular stimulus GO:0009991 72 72 1,000 0,02985516 0,05929209 ! response to oxidative stress GO:0006979 76 75 1,000 0,03219056 0,06386136 ! lactation GO:0007595 10 9 0,000 0,03352121 0,06642966 ! positive regulation of cell size GO:0045793 9 9 0,000 0,03352121 0,06635831 ! positive regulation of cell projection organization GO:0031346 9 9 0,000 0,03352121 0,06628711 ! regulation of membrane protein ectodomain proteolysis GO:0051043 9 9 0,000 0,03352121 0,06621606 ! positive regulation of protein complex assembly GO:0031334 9 9 0,000 0,03352121 0,06614516 ! cortical actin cytoskeleton organization GO:0030866 10 9 0,000 0,03352121 0,06607442 ! negative regulation of cell cycle process GO:0010948 9 9 0,000 0,03352121 0,06600383 ! viral genome replication GO:0019079 9 9 0,000 0,03352121 0,06593339 ! phospholipid catabolic process GO:0009395 9 9 0,000 0,03352121 0,0658631 ! copper ion transport GO:0006825 9 9 0,000 0,03352121 0,06579295 ! lipid phosphorylation GO:0046834 9 9 0,000 0,03352121 0,06572296 ! aminoglycan catabolic process GO:0006026 9 9 0,000 0,03352121 0,06565312 ! Golgi vesicle budding GO:0048194 9 9 0,000 0,03352121 0,06558342 ! regulation of cell-cell adhesion GO:0022407 9 9 0,000 0,03352121 0,06551387 ! RNA polyadenylation GO:0043631 9 9 0,000 0,03352121 0,06544447 GO:0006378|mRNA polyadenylation, ! gamma-aminobutyric acid signaling pathway GO:0007214 9 9 0,000 0,03352121 0,06537522 ! regulation of postsynaptic membrane potential GO:0060078 9 9 0,000 0,03352121 0,06530611 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 9 9 0,000 0,03352121 0,06523715 ! negative regulation of cytokine biosynthetic process GO:0042036 9 9 0,000 0,03352121 0,06516834 ! phospholipid efflux GO:0033700 9 9 0,000 0,03352121 0,06509967 ! response to alkaloid GO:0043279 10 9 0,000 0,03352121 0,06503114 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 9 9 0,000 0,03352121 0,06496276 ! cytokine biosynthetic process GO:0042089 9 9 0,000 0,03352121 0,06489452 GO:0042107|cytokine metabolic process, ! negative regulation of gene expression, epigenetic GO:0045814 9 9 0,000 0,03352121 0,06482643 ! regulation of interleukin-2 biosynthetic process GO:0045076 9 9 0,000 0,03352121 0,06475847 ! response to ethanol GO:0045471 9 9 0,000 0,03352121 0,06469066 ! pyrimidine ribonucleotide metabolic process GO:0009218 9 9 0,000 0,03352121 0,064623 ! activation of pro-apoptotic gene products GO:0008633 9 9 0,000 0,03352121 0,06455547 ! methionine metabolic process GO:0006555 9 9 0,000 0,03352121 0,06448808 ! glutamine metabolic process GO:0006541 9 9 0,000 0,03352121 0,06442084 ! cerebral cortex development GO:0021987 9 9 0,000 0,03352121 0,06435373 ! response to osmotic stress GO:0006970 9 9 0,000 0,03352121 0,06428677 ! pigmentation during development GO:0048066 9 9 0,000 0,03352121 0,06421994 ! reverse cholesterol transport GO:0043691 9 9 0,000 0,03352121 0,06415325 ! central nervous system neuron development GO:0021954 10 9 0,000 0,03352121 0,0640867 ! pyrimidine ribonucleoside metabolic process GO:0046131 9 9 0,000 0,03352121 0,06402029 ! nucleobase biosynthetic process GO:0046112 9 9 0,000 0,03352121 0,06395402 ! substrate-bound cell migration GO:0006929 9 9 0,000 0,03352121 0,06388788 ! neurotransmitter metabolic process GO:0042133 11 9 0,000 0,03352121 0,06382188 ! negative regulation of caspase activity GO:0043154 9 9 0,000 0,03352121 0,06375602 ! L-glutamate transport GO:0015813 9 9 0,000 0,03352121 0,06369029 GO:0015800|acidic amino acid transport, ! peptide secretion GO:0002790 9 9 0,000 0,03352121 0,0636247 ! regulation of dephosphorylation GO:0035303 9 9 0,000 0,03352121 0,06355924 ! cotranslational protein targeting to membrane GO:0006613 10 9 0,000 0,03352121 0,06349392 ! positive regulation of alpha-beta T cell differentiation GO:0046638 9 9 0,000 0,03352121 0,06342873 ! ventricular cardiac muscle morphogenesis GO:0055010 9 9 0,000 0,03352121 0,06336368 ! behavioral interaction between organisms GO:0051705 9 9 0,000 0,03352121 0,06329875 ! negative regulation of protein import into nucleus GO:0042308 9 9 0,000 0,03352121 0,06323396 ! DNA replication initiation GO:0006270 9 9 0,000 0,03352121 0,06316931 ! prostaglandin metabolic process GO:0006693 9 9 0,000 0,03352121 0,06310478 GO:0006692|prostanoid metabolic process, ! T cell differentiation in the thymus GO:0033077 9 9 0,000 0,03352121 0,06304039 ! histone acetylation GO:0016573 9 9 0,000 0,03352121 0,06297613 ! DNA fragmentation involved in apoptosis GO:0006309 9 9 0,000 0,03352121 0,062912 ! regulation of immunoglobulin mediated immune response GO:0002889 9 9 0,000 0,03352121 0,062848 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 10 9 0,000 0,03352121 0,06278413 ! positive regulation of oxidoreductase activity GO:0051353 9 9 0,000 0,03352121 0,06272039 ! positive regulation of cytokine secretion GO:0050715 9 9 0,000 0,03352121 0,06265678 ! negative regulation of inflammatory response GO:0050728 9 9 0,000 0,03352121 0,0625933 ! negative regulation of protein secretion GO:0050709 9 9 0,000 0,03352121 0,06252994 ! positive regulation of transmission of nerve impulse GO:0051971 9 9 0,000 0,03352121 0,06246672 ! collagen catabolic process GO:0030574 9 9 0,000 0,03352121 0,06240362 ! aromatic amino acid family catabolic process GO:0009074 9 9 0,000 0,03352121 0,06234065 ! purine base metabolic process GO:0006144 9 9 0,000 0,03352121 0,06227781 ! gas transport GO:0015669 9 9 0,000 0,03352121 0,06221509 ! cholesterol efflux GO:0033344 9 9 0,000 0,03352121 0,0621525 ! regulation of leukocyte mediated cytotoxicity GO:0001910 9 9 0,000 0,03352121 0,06209003 ! estrogen receptor signaling pathway GO:0030520 9 9 0,000 0,03352121 0,06202769 ! somatic recombination of immunoglobulin gene segments GO:0016447 9 9 0,000 0,03352121 0,06196548 ! regulation of actin filament bundle formation GO:0032231 10 9 0,000 0,03352121 0,06190339 ! defense response to virus GO:0051607 9 9 0,000 0,03352121 0,06184142 ! regulation of calcium-mediated signaling GO:0050848 9 9 0,000 0,03352121 0,06177958 ! actin filament-based movement GO:0030048 9 9 0,000 0,03352121 0,06171787 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 9 9 0,000 0,03352121 0,06165627 ! cell morphogenesis involved in differentiation GO:0000904 82 77 1,000 0,03378668 0,06208261 ! regulation of protein modification process GO:0031399 79 78 1,000 0,0345963 0,06350696 ! microtubule-based movement GO:0007018 82 78 1,000 0,0345963 0,06344377 ! neuron projection development GO:0031175 85 80 1,000 0,03623834 0,06638893 ! lymphocyte activation GO:0046649 82 81 1,000 0,03707064 0,06784626 ! lipid catabolic process GO:0016042 82 81 1,000 0,03707064 0,06777895 ! protein import into nucleus, docking GO:0000059 10 10 0,000 0,03717838 0,06790858 ! regulation of protein ubiquitination GO:0031396 10 10 0,000 0,03717838 0,06784134 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 10 10 0,000 0,03717838 0,06777424 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 10 10 0,000 0,03717838 0,06770727 ! ER-associated protein catabolic process GO:0030433 10 10 0,000 0,03717838 0,06764043 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of cell killing GO:0031341 10 10 0,000 0,03717838 0,06757372 ! neuron maturation GO:0042551 10 10 0,000 0,03717838 0,06750715 ! pteridine and derivative metabolic process GO:0042558 10 10 0,000 0,03717838 0,06744071 ! positive regulation of anti-apoptosis GO:0045768 10 10 0,000 0,03717838 0,06737439 GO:0045767|regulation of anti-apoptosis, ! cortical cytoskeleton organization GO:0030865 11 10 0,000 0,03717838 0,06730821 ! regulation of lipid biosynthetic process GO:0046890 10 10 0,000 0,03717838 0,06724216 ! reciprocal meiotic recombination GO:0007131 10 10 0,000 0,03717838 0,06717623 ! hormone secretion GO:0046879 10 10 0,000 0,03717838 0,06711044 ! glucosamine metabolic process GO:0006041 10 10 0,000 0,03717838 0,06704477 GO:0006044|N-acetylglucosamine metabolic process, ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 10 10 0,000 0,03717838 0,06697923 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! inositol metabolic process GO:0006020 10 10 0,000 0,03717838 0,06691382 ! cAMP metabolic process GO:0046058 10 10 0,000 0,03717838 0,06684854 ! vesicle targeting, to, from or within Golgi GO:0048199 10 10 0,000 0,03717838 0,06678339 ! transcription from RNA polymerase III promoter GO:0006383 10 10 0,000 0,03717838 0,06671836 ! forelimb morphogenesis GO:0035136 10 10 0,000 0,03717838 0,06665346 ! glial cell development GO:0021782 10 10 0,000 0,03717838 0,06658868 ! phototransduction GO:0007602 11 10 0,000 0,03717838 0,06652404 ! calcium-independent cell-cell adhesion GO:0016338 10 10 0,000 0,03717838 0,06645951 ! auditory receptor cell differentiation GO:0042491 10 10 0,000 0,03717838 0,06639511 ! fat cell differentiation GO:0045444 10 10 0,000 0,03717838 0,06633084 ! myoblast differentiation GO:0045445 10 10 0,000 0,03717838 0,06626669 ! centrosome cycle GO:0007098 10 10 0,000 0,03717838 0,06620266 ! inactivation of MAPK activity GO:0000188 10 10 0,000 0,03717838 0,06613876 ! positive regulation of proteolysis GO:0045862 10 10 0,000 0,03717838 0,06607498 ! response to carbohydrate stimulus GO:0009743 10 10 0,000 0,03717838 0,06601133 ! regulation of survival gene product expression GO:0045884 10 10 0,000 0,03717838 0,06594779 ! induction of apoptosis via death domain receptors GO:0008625 10 10 0,000 0,03717838 0,06588438 ! epidermis morphogenesis GO:0048730 10 10 0,000 0,03717838 0,06582109 ! protein polyubiquitination GO:0000209 10 10 0,000 0,03717838 0,06575792 ! glutamate metabolic process GO:0006536 11 10 0,000 0,03717838 0,06569488 ! plasma membrane organization GO:0007009 10 10 0,000 0,03717838 0,06563195 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 10 10 0,000 0,03717838 0,06556915 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cell-substrate junction assembly GO:0007044 11 10 0,000 0,03717838 0,06550646 ! lysosomal transport GO:0007041 10 10 0,000 0,03717838 0,06544389 ! cellular response to unfolded protein GO:0034620 10 10 0,000 0,03717838 0,06538145 GO:0030968|endoplasmic reticulum unfolded protein response, ! central nervous system neuron differentiation GO:0021953 11 10 0,000 0,03717838 0,06531912 ! purine ribonucleoside metabolic process GO:0046128 10 10 0,000 0,03717838 0,06525691 GO:0042278|purine nucleoside metabolic process, ! vesicle coating GO:0006901 10 10 0,000 0,03717838 0,06519482 ! exocrine system development GO:0035272 10 10 0,000 0,03717838 0,06513285 ! cell structure disassembly during apoptosis GO:0006921 10 10 0,000 0,03717838 0,06507099 ! embryo implantation GO:0007566 11 10 0,000 0,03717838 0,06500926 ! regulation of protein binding GO:0043393 11 10 0,000 0,03717838 0,06494764 ! protein targeting to peroxisome GO:0006625 10 10 0,000 0,03717838 0,06488613 ! protein targeting to mitochondrion GO:0006626 10 10 0,000 0,03717838 0,06482475 GO:0070585|protein localization in mitochondrion, ! regulation of alpha-beta T cell differentiation GO:0046637 10 10 0,000 0,03717838 0,06476348 ! intermediate filament cytoskeleton organization GO:0045104 10 10 0,000 0,03717838 0,06470232 ! protein export from nucleus GO:0006611 10 10 0,000 0,03717838 0,06464128 ! negative regulation of immune response GO:0050777 10 10 0,000 0,03717838 0,06458036 ! cytolysis GO:0019835 10 10 0,000 0,03717838 0,06451954 ! positive regulation of biomineral formation GO:0070169 10 10 0,000 0,03717838 0,06445885 GO:0030501|positive regulation of bone mineralization, ! mismatch repair GO:0006298 10 10 0,000 0,03717838 0,06439827 ! regulation of B cell differentiation GO:0045577 10 10 0,000 0,03717838 0,0643378 ! histone deacetylation GO:0016575 10 10 0,000 0,03717838 0,06427745 ! mRNA splice site selection GO:0006376 11 10 0,000 0,03717838 0,0642172 ! synaptic vesicle transport GO:0048489 11 10 0,000 0,03717838 0,06415708 ! gland morphogenesis GO:0022612 10 10 0,000 0,03717838 0,06409706 ! positive regulation of neurological system process GO:0031646 10 10 0,000 0,03717838 0,06403716 ! sphingolipid biosynthetic process GO:0030148 10 10 0,000 0,03717838 0,06397736 GO:0046467|membrane lipid biosynthetic process, ! sphingolipid catabolic process GO:0030149 10 10 0,000 0,03717838 0,06391768 GO:0046466|membrane lipid catabolic process, ! nerve-nerve synaptic transmission GO:0007270 10 10 0,000 0,03717838 0,06385811 ! regulation of erythrocyte differentiation GO:0045646 10 10 0,000 0,03717838 0,06379866 ! regulation of epidermis development GO:0045682 10 10 0,000 0,03717838 0,06373931 ! folic acid and derivative metabolic process GO:0006760 10 10 0,000 0,03717838 0,06368007 ! negative regulation of neuron differentiation GO:0045665 10 10 0,000 0,03717838 0,06362094 ! aspartate family amino acid biosynthetic process GO:0009067 10 10 0,000 0,03717838 0,06356193 ! regulation of BMP signaling pathway GO:0030510 10 10 0,000 0,03717838 0,06350302 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 10 10 0,000 0,03717838 0,06344422 ! lymphocyte homeostasis GO:0002260 10 10 0,000 0,03717838 0,06338553 ! epithelial to mesenchymal transition GO:0001837 10 10 0,000 0,03717838 0,06332695 ! mRNA 3'-end processing GO:0031124 10 10 0,000 0,03717838 0,06326847 ! antigen receptor-mediated signaling pathway GO:0050851 10 10 0,000 0,03717838 0,06321011 ! negative regulation of coagulation GO:0050819 11 10 0,000 0,03717838 0,06315185 ! protein stabilization GO:0050821 10 10 0,000 0,03717838 0,0630937 ! positive regulation of response to stimulus GO:0048584 86 85 1,000 0,04047346 0,06862244 ! positive regulation of cell differentiation GO:0045597 87 85 1,000 0,04047346 0,06855937 ! protein secretion GO:0009306 11 11 0,000 0,04082225 0,06908669 ! oligosaccharide metabolic process GO:0009311 11 11 0,000 0,04082225 0,06902331 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 11 11 0,000 0,04082225 0,06896004 ! myeloid leukocyte differentiation GO:0002573 12 11 0,000 0,04082225 0,06889689 ! negative regulation of defense response GO:0031348 11 11 0,000 0,04082225 0,06883385 ! G1 phase of mitotic cell cycle GO:0000080 12 11 0,000 0,04082225 0,06877093 ! determination of bilateral symmetry GO:0009855 11 11 0,000 0,04082225 0,06870813 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! positive regulation of hormone secretion GO:0046887 11 11 0,000 0,04082225 0,06864544 ! phosphatidylinositol metabolic process GO:0046488 11 11 0,000 0,04082225 0,06858286 ! skin development GO:0043588 11 11 0,000 0,04082225 0,0685204 ! cellular component assembly involved in morphogenesis GO:0010927 11 11 0,000 0,04082225 0,06845806 ! signal complex assembly GO:0007172 11 11 0,000 0,04082225 0,06839582 ! microtubule-based transport GO:0010970 11 11 0,000 0,04082225 0,0683337 ! endothelial cell migration GO:0043542 11 11 0,000 0,04082225 0,06827169 ! peroxisomal transport GO:0043574 11 11 0,000 0,04082225 0,06820979 ! protein amino acid methylation GO:0006479 11 11 0,000 0,04082225 0,06814801 GO:0008213|protein amino acid alkylation, ! protein amino acid acetylation GO:0006473 11 11 0,000 0,04082225 0,06808634 ! heart contraction GO:0060047 11 11 0,000 0,04082225 0,06802478 GO:0003015|heart process, ! detection of light stimulus involved in sensory perception GO:0050962 12 11 0,000 0,04082225 0,06796333 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 11 11 0,000 0,04082225 0,06790199 ! T cell proliferation GO:0042098 11 11 0,000 0,04082225 0,06784076 ! regulation of transmembrane transporter activity GO:0022898 11 11 0,000 0,04082225 0,06777964 GO:0032412|regulation of ion transmembrane transporter activity, GO:0032409|regulation of transporter activity, ! negative regulation of endothelial cell proliferation GO:0001937 11 11 0,000 0,04082225 0,06771863 ! regulation of viral genome replication GO:0045069 11 11 0,000 0,04082225 0,06765774 ! activation of MAPKK activity GO:0000186 12 11 0,000 0,04082225 0,06759695 ! smooth muscle contraction GO:0006939 11 11 0,000 0,04082225 0,06753627 ! cellular macromolecular complex disassembly GO:0034623 12 11 0,000 0,04082225 0,0674757 ! digestive system process GO:0022600 11 11 0,000 0,04082225 0,06741524 ! mitotic spindle organization GO:0007052 11 11 0,000 0,04082225 0,06735488 ! fucose metabolic process GO:0006004 11 11 0,000 0,04082225 0,06729464 ! membrane budding GO:0006900 11 11 0,000 0,04082225 0,0672345 ! apoptotic nuclear changes GO:0030262 11 11 0,000 0,04082225 0,06717447 ! monoamine transport GO:0015844 11 11 0,000 0,04082225 0,06711454 ! regulation of cellular ketone metabolic process GO:0010565 11 11 0,000 0,04082225 0,06705473 ! response to lipopolysaccharide GO:0032496 11 11 0,000 0,04082225 0,06699502 ! body fluid secretion GO:0007589 11 11 0,000 0,04082225 0,06693541 ! positive regulation of alpha-beta T cell activation GO:0046635 11 11 0,000 0,04082225 0,06687591 ! intermediate filament-based process GO:0045103 11 11 0,000 0,04082225 0,06681652 ! cardiac muscle tissue morphogenesis GO:0055008 11 11 0,000 0,04082225 0,06675723 GO:0060415|muscle tissue morphogenesis, ! membrane depolarization GO:0051899 11 11 0,000 0,04082225 0,06669805 ! regulation of interleukin-2 production GO:0032663 11 11 0,000 0,04082225 0,06663897 ! regulation of ARF GTPase activity GO:0032312 11 11 0,000 0,04082225 0,06658 ! oogenesis GO:0048477 11 11 0,000 0,04082225 0,06652113 ! negative regulation of angiogenesis GO:0016525 11 11 0,000 0,04082225 0,06646237 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 11 11 0,000 0,04082225 0,06640371 ! vitamin transport GO:0051180 11 11 0,000 0,04082225 0,06634515 ! muscle maintenance GO:0046716 12 11 0,000 0,04082225 0,0662867 ! vitamin A metabolic process GO:0006776 11 11 0,000 0,04082225 0,06622835 ! steroid catabolic process GO:0006706 11 11 0,000 0,04082225 0,0661701 ! endocrine process GO:0050886 11 11 0,000 0,04082225 0,06611195 GO:0001990|regulation of systemic arterial blood pressure by hormone, ! aromatic amino acid family metabolic process GO:0009072 11 11 0,000 0,04082225 0,06605391 ! somatic diversification of immunoglobulins GO:0016445 11 11 0,000 0,04082225 0,06599597 ! RNA 3'-end processing GO:0031123 11 11 0,000 0,04082225 0,06593813 ! hexose metabolic process GO:0019318 87 86 1,000 0,04134227 0,06671962 ! translational initiation GO:0006413 12 12 0,000 0,04445285 0,07167682 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 12 12 0,000 0,04445285 0,07161417 ! positive regulation of angiogenesis GO:0045766 12 12 0,000 0,04445285 0,07155162 ! initiation of viral infection GO:0019059 12 12 0,000 0,04445285 0,07148919 ! DNA catabolic process, endonucleolytic GO:0000737 12 12 0,000 0,04445285 0,07142686 ! iron ion transport GO:0006826 13 12 0,000 0,04445285 0,07136464 ! phosphatidylcholine metabolic process GO:0046470 12 12 0,000 0,04445285 0,07130253 ! amino sugar metabolic process GO:0006040 12 12 0,000 0,04445285 0,07124053 ! post-Golgi vesicle-mediated transport GO:0006892 12 12 0,000 0,04445285 0,07117863 ! protein amino acid ADP-ribosylation GO:0006471 12 12 0,000 0,04445285 0,07111685 ! heterophilic cell adhesion GO:0007157 12 12 0,000 0,04445285 0,07105517 ! collagen metabolic process GO:0032963 12 12 0,000 0,04445285 0,07099359 ! hindlimb morphogenesis GO:0035137 12 12 0,000 0,04445285 0,07093213 ! xenobiotic metabolic process GO:0006805 12 12 0,000 0,04445285 0,07087077 ! glutamate signaling pathway GO:0007215 12 12 0,000 0,04445285 0,07080951 ! C21-steroid hormone metabolic process GO:0008207 13 12 0,000 0,04445285 0,07074836 ! regulation of muscle cell differentiation GO:0051147 13 12 0,000 0,04445285 0,07068732 ! cellular response to hydrogen peroxide GO:0070301 12 12 0,000 0,04445285 0,07062638 GO:0042744|hydrogen peroxide catabolic process, ! negative regulation of peptidase activity GO:0010466 12 12 0,000 0,04445285 0,07056555 ! actomyosin structure organization GO:0031032 12 12 0,000 0,04445285 0,07050482 ! microtubule organizing center organization GO:0031023 12 12 0,000 0,04445285 0,0704442 GO:0051297|centrosome organization, ! positive regulation of endocytosis GO:0045807 12 12 0,000 0,04445285 0,07038368 ! retinoid metabolic process GO:0001523 12 12 0,000 0,04445285 0,07032327 GO:0016101|diterpenoid metabolic process, ! mitotic chromosome condensation GO:0007076 12 12 0,000 0,04445285 0,07026296 ! positive regulation of innate immune response GO:0045089 12 12 0,000 0,04445285 0,07020275 ! GPI anchor biosynthetic process GO:0006506 12 12 0,000 0,04445285 0,07014264 GO:0006505|GPI anchor metabolic process, ! glycoprotein catabolic process GO:0006516 13 12 0,000 0,04445285 0,07008264 ! acute-phase response GO:0006953 12 12 0,000 0,04445285 0,07002274 ! deoxyribonucleotide catabolic process GO:0009264 12 12 0,000 0,04445285 0,06996294 ! vacuolar transport GO:0007034 12 12 0,000 0,04445285 0,06990325 ! polysaccharide catabolic process GO:0000272 12 12 0,000 0,04445285 0,06984365 ! vesicle docking during exocytosis GO:0006904 12 12 0,000 0,04445285 0,06978416 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 12 12 0,000 0,04445285 0,06972477 ! barbed-end actin filament capping GO:0051016 12 12 0,000 0,04445285 0,06966548 GO:0051693|actin filament capping, ! male gonad development GO:0008584 12 12 0,000 0,04445285 0,06960629 ! regulation of insulin secretion GO:0050796 12 12 0,000 0,04445285 0,0695472 ! regulation of alpha-beta T cell activation GO:0046634 12 12 0,000 0,04445285 0,06948822 ! renal system process GO:0003014 12 12 0,000 0,04445285 0,06942933 ! regulation of tumor necrosis factor production GO:0032680 12 12 0,000 0,04445285 0,06937054 ! regulation of steroid metabolic process GO:0019218 12 12 0,000 0,04445285 0,06931185 ! fibroblast growth factor receptor signaling pathway GO:0008543 12 12 0,000 0,04445285 0,06925326 ! regulation of interleukin-6 production GO:0032675 12 12 0,000 0,04445285 0,06919477 ! pallium development GO:0021543 13 12 0,000 0,04445285 0,06913638 ! cell fate determination GO:0001709 12 12 0,000 0,04445285 0,06907808 ! regulation of chromosome organization GO:0033044 12 12 0,000 0,04445285 0,06901989 ! positive regulation of multicellular organism growth GO:0040018 12 12 0,000 0,04445285 0,06896179 ! somitogenesis GO:0001756 13 12 0,000 0,04445285 0,06890379 ! G1 phase GO:0051318 13 12 0,000 0,04445285 0,06884589 ! regulation of response to biotic stimulus GO:0002831 12 12 0,000 0,04445285 0,06878808 ! positive regulation of adaptive immune response GO:0002821 12 12 0,000 0,04445285 0,06873037 ! detection of light stimulus GO:0009583 13 12 0,000 0,04445285 0,06867276 ! synaptogenesis GO:0007416 12 12 0,000 0,04445285 0,06861525 ! fat-soluble vitamin metabolic process GO:0006775 12 12 0,000 0,04445285 0,06855783 ! hormone transport GO:0009914 12 12 0,000 0,04445285 0,06850051 ! neurotransmitter secretion GO:0007269 14 12 0,000 0,04445285 0,06844328 ! heme biosynthetic process GO:0006783 12 12 0,000 0,04445285 0,06838615 ! spermatid differentiation GO:0048515 13 12 0,000 0,04445285 0,06832911 GO:0007286|spermatid development, ! aromatic compound catabolic process GO:0019439 13 12 0,000 0,04445285 0,06827217 ! pyrimidine nucleotide biosynthetic process GO:0006221 12 12 0,000 0,04445285 0,06821533 ! neural tube closure GO:0001843 13 12 0,000 0,04445285 0,06815857 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! regulation of mitotic metaphase/anaphase transition GO:0030071 13 12 0,000 0,04445285 0,06810192 ! negative regulation of translation GO:0017148 12 12 0,000 0,04445285 0,06804535 ! regulation of microtubule polymerization or depolymerization GO:0031110 12 12 0,000 0,04445285 0,06798888 ! fatty acid metabolic process GO:0006631 93 92 1,000 0,04670241 0,07137026 ! energy derivation by oxidation of organic compounds GO:0015980 94 92 1,000 0,04670241 0,07131113 ! positive regulation of immune system process GO:0002684 92 92 1,000 0,04670241 0,0712521 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 13 13 0,000 0,04807024 0,07327829 GO:0016444|somatic cell DNA recombination, ! negative regulation of actin filament polymerization GO:0030837 13 13 0,000 0,04807024 0,07321773 ! phenol metabolic process GO:0018958 13 13 0,000 0,04807024 0,07315727 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, GO:0009712|catechol metabolic process, ! G2/M transition of mitotic cell cycle GO:0000086 13 13 0,000 0,04807024 0,07309691 ! negative regulation of hormone secretion GO:0046888 13 13 0,000 0,04807024 0,07303665 ! 2'-deoxyribonucleotide metabolic process GO:0009394 13 13 0,000 0,04807024 0,07297649 GO:0019692|deoxyribose phosphate metabolic process, ! intra-Golgi vesicle-mediated transport GO:0006891 13 13 0,000 0,04807024 0,07291642 ! glycosaminoglycan biosynthetic process GO:0006024 13 13 0,000 0,04807024 0,07285646 ! positive regulation of JAK-STAT cascade GO:0046427 13 13 0,000 0,04807024 0,07279659 ! regeneration GO:0031099 13 13 0,000 0,04807024 0,07273683 ! keratinization GO:0031424 13 13 0,000 0,04807024 0,07267716 ! post-embryonic development GO:0009791 14 13 0,000 0,04807024 0,07261759 ! negative regulation of protein modification process GO:0031400 13 13 0,000 0,04807024 0,07255811 ! patterning of blood vessels GO:0001569 13 13 0,000 0,04807024 0,07249873 ! regulation of DNA recombination GO:0000018 13 13 0,000 0,04807024 0,07243946 ! regulation of innate immune response GO:0045088 13 13 0,000 0,04807024 0,07238027 ! multicellular organismal macromolecule metabolic process GO:0044259 13 13 0,000 0,04807024 0,07232119 ! response to corticosteroid stimulus GO:0031960 13 13 0,000 0,04807024 0,0722622 GO:0051384|response to glucocorticoid stimulus, ! multicellular organismal catabolic process GO:0044243 13 13 0,000 0,04807024 0,0722033 ! autophagy GO:0006914 13 13 0,000 0,04807024 0,07214451 ! receptor metabolic process GO:0043112 14 13 0,000 0,04807024 0,0720858 ! actin filament bundle formation GO:0051017 13 13 0,000 0,04807024 0,0720272 ! negative regulation of protein catabolic process GO:0042177 13 13 0,000 0,04807024 0,07196869 ! coenzyme catabolic process GO:0009109 13 13 0,000 0,04807024 0,07191027 GO:0046356|acetyl-CoA catabolic process, GO:0006099|tricarboxylic acid cycle, ! negative regulation of protein kinase cascade GO:0010741 13 13 0,000 0,04807024 0,07185195 ! purine nucleoside monophosphate metabolic process GO:0009126 13 13 0,000 0,04807024 0,07179372 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of peptide secretion GO:0002791 13 13 0,000 0,04807024 0,07173559 ! regulation of viral reproduction GO:0050792 13 13 0,000 0,04807024 0,07167755 ! nucleobase metabolic process GO:0009112 13 13 0,000 0,04807024 0,07161961 ! regulation of axonogenesis GO:0050770 14 13 0,000 0,04807024 0,07156176 ! positive regulation of neurogenesis GO:0050769 13 13 0,000 0,04807024 0,071504 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 14 13 0,000 0,04807024 0,07144633 ! nucleotide-excision repair, DNA gap filling GO:0006297 13 13 0,000 0,04807024 0,07138876 ! vasodilation GO:0042311 14 13 0,000 0,04807024 0,07133128 ! positive regulation of leukocyte mediated immunity GO:0002705 13 13 0,000 0,04807024 0,0712739 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 13 13 0,000 0,04807024 0,0712166 ! glycosphingolipid metabolic process GO:0006687 13 13 0,000 0,04807024 0,0711594 GO:0006664|glycolipid metabolic process, ! neural crest cell migration GO:0001755 14 13 0,000 0,04807024 0,07110229 ! neutrophil chemotaxis GO:0030593 14 13 0,000 0,04807024 0,07104527 ! long-chain fatty acid transport GO:0015909 13 13 0,000 0,04807024 0,07098834 ! immunoglobulin production GO:0002377 13 13 0,000 0,04807024 0,07093151 GO:0002440|production of molecular mediator of immune response, ! negative regulation of Wnt receptor signaling pathway GO:0030178 13 13 0,000 0,04807024 0,07087476 ! cell-cell junction organization GO:0045216 13 13 0,000 0,04807024 0,07081811 ! negative regulation of myeloid cell differentiation GO:0045638 13 13 0,000 0,04807024 0,07076154 ! response to cytokine stimulus GO:0034097 13 13 0,000 0,04807024 0,07070507 ! activation of JUN kinase activity GO:0007257 13 13 0,000 0,04807024 0,07064869 ! terpenoid metabolic process GO:0006721 13 13 0,000 0,04807024 0,07059239 ! alkene biosynthetic process GO:0043450 13 13 0,000 0,04807024 0,07053619 GO:0019370|leukotriene biosynthetic process, ! purine nucleotide catabolic process GO:0006195 13 13 0,000 0,04807024 0,07048007 ! porphyrin biosynthetic process GO:0006779 13 13 0,000 0,04807024 0,07042405 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of cytokine production GO:0001818 13 13 0,000 0,04807024 0,07036811 ! pyrimidine nucleoside metabolic process GO:0006213 13 13 0,000 0,04807024 0,07031226 ! blastocyst development GO:0001824 13 13 0,000 0,04807024 0,07025651 ! telomere organization GO:0032200 13 13 0,000 0,04807024 0,07020084 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 13 13 0,000 0,04807024 0,07014525 ! regulation of amine transport GO:0051952 13 13 0,000 0,04807024 0,07008976 ! inner ear receptor cell differentiation GO:0060113 13 13 0,000 0,04807024 0,07003435 ! epidermis development GO:0008544 94 94 1,000 0,04854377 0,07066839 ! sulfur amino acid metabolic process GO:0000096 14 14 0,000 0,05167446 0,07516656 ! regulation of interferon-gamma production GO:0032649 14 14 0,000 0,05167446 0,07510728 ! cellular aldehyde metabolic process GO:0006081 14 14 0,000 0,05167446 0,07504809 ! acetyl-CoA metabolic process GO:0006084 14 14 0,000 0,05167446 0,074989 ! cellular iron ion homeostasis GO:0006879 14 14 0,000 0,05167446 0,07493 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 14 14 0,000 0,05167446 0,07487109 ! regulation of neuron projection development GO:0010975 15 14 0,000 0,05167446 0,07481228 ! protein amino acid deacetylation GO:0006476 14 14 0,000 0,05167446 0,07475356 ! aminoglycan biosynthetic process GO:0006023 14 14 0,000 0,05167446 0,07469493 ! vesicle docking GO:0048278 14 14 0,000 0,05167446 0,07463639 ! superoxide metabolic process GO:0006801 15 14 0,000 0,05167446 0,07457794 ! macromolecular complex disassembly GO:0032984 15 14 0,000 0,05167446 0,07451959 ! calcium-dependent cell-cell adhesion GO:0016339 14 14 0,000 0,05167446 0,07446132 ! mechanoreceptor differentiation GO:0042490 14 14 0,000 0,05167446 0,07440315 ! isoprenoid biosynthetic process GO:0008299 14 14 0,000 0,05167446 0,07434507 ! hair cycle GO:0042633 14 14 0,000 0,05167446 0,07428707 GO:0022404|molting cycle process, GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042303|molting cycle, ! negative regulation of epithelial cell proliferation GO:0050680 14 14 0,000 0,05167446 0,07422917 ! immune response-activating cell surface receptor signaling pathway GO:0002429 14 14 0,000 0,05167446 0,07417136 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! response to retinoic acid GO:0032526 14 14 0,000 0,05167446 0,07411364 GO:0033189|response to vitamin A, ! multicellular organismal response to stress GO:0033555 14 14 0,000 0,05167446 0,07405601 ! lysosome organization GO:0007040 14 14 0,000 0,05167446 0,07399847 ! actin polymerization or depolymerization GO:0008154 15 14 0,000 0,05167446 0,07394102 ! D-ribose metabolic process GO:0006014 14 14 0,000 0,05167446 0,07388365 ! negative regulation of phosphorus metabolic process GO:0010563 14 14 0,000 0,05167446 0,07382638 GO:0045936|negative regulation of phosphate metabolic process, ! peptide transport GO:0015833 14 14 0,000 0,05167446 0,07376919 ! primary neural tube formation GO:0014020 15 14 0,000 0,05167446 0,0737121 ! peptide cross-linking GO:0018149 14 14 0,000 0,05167446 0,07365509 ! vitamin biosynthetic process GO:0009110 14 14 0,000 0,05167446 0,07359817 ! response to organic cyclic substance GO:0014070 15 14 0,000 0,05167446 0,07354134 ! leukotriene metabolic process GO:0006691 14 14 0,000 0,05167446 0,07348459 ! regulation of vasoconstriction GO:0019229 14 14 0,000 0,05167446 0,07342793 ! DNA modification GO:0006304 14 14 0,000 0,05167446 0,07337136 ! collagen fibril organization GO:0030199 14 14 0,000 0,05167446 0,07331488 ! proteoglycan biosynthetic process GO:0030166 14 14 0,000 0,05167446 0,07325848 ! regulation of blood coagulation GO:0030193 15 14 0,000 0,05167446 0,07320218 ! positive regulation of inflammatory response GO:0050729 14 14 0,000 0,05167446 0,07314595 ! group transfer coenzyme metabolic process GO:0006752 14 14 0,000 0,05167446 0,07308982 ! neuromuscular process controlling balance GO:0050885 14 14 0,000 0,05167446 0,07303377 ! aspartate family amino acid metabolic process GO:0009066 14 14 0,000 0,05167446 0,0729778 ! response to molecule of bacterial origin GO:0002237 14 14 0,000 0,05167446 0,07292192 ! negative regulation of protein polymerization GO:0032272 14 14 0,000 0,05167446 0,07286613 ! posttranscriptional regulation of gene expression GO:0010608 98 98 1,000 0,05230563 0,07369976 ! blood circulation GO:0008015 99 98 1,000 0,05230563 0,07364346 GO:0003013|circulatory system process, ! muscle organ development GO:0007517 102 100 1,000 0,05422519 0,0762878 ! negative regulation of transcription from RNA polymerase II promoter GO:0000122 103 100 1,000 0,05422519 0,07622961 ! hemopoiesis GO:0030097 104 100 1,000 0,05422519 0,07617151 ! positive regulation of fibroblast proliferation GO:0048146 15 15 0,000 0,05526556 0,07757382 ! negative regulation of actin filament depolymerization GO:0030835 15 15 0,000 0,05526556 0,07751478 ! positive regulation of ossification GO:0045778 15 15 0,000 0,05526556 0,07745583 GO:0046852|positive regulation of bone remodeling, GO:0034105|positive regulation of tissue remodeling, ! negative regulation of protein complex assembly GO:0031333 15 15 0,000 0,05526556 0,07739698 ! protein amino acid O-linked glycosylation GO:0006493 15 15 0,000 0,05526556 0,07733821 ! cellular polysaccharide biosynthetic process GO:0033692 15 15 0,000 0,05526556 0,07727953 ! proteoglycan metabolic process GO:0006029 15 15 0,000 0,05526556 0,07722094 ! response to vitamin GO:0033273 15 15 0,000 0,05526556 0,07716244 ! regulation of transcription factor import into nucleus GO:0042990 15 15 0,000 0,05526556 0,07710403 ! striated muscle cell differentiation GO:0051146 16 15 0,000 0,05526556 0,0770457 ! detection of stimulus involved in sensory perception GO:0050906 16 15 0,000 0,05526556 0,07698747 ! antigen processing and presentation of peptide antigen GO:0048002 15 15 0,000 0,05526556 0,07692932 ! regulation of smooth muscle contraction GO:0006940 15 15 0,000 0,05526556 0,07687126 ! deoxyribonucleotide metabolic process GO:0009262 15 15 0,000 0,05526556 0,07681329 ! complement activation, classical pathway GO:0006958 15 15 0,000 0,05526556 0,0767554 ! heme metabolic process GO:0042168 15 15 0,000 0,05526556 0,07669761 ! chromosome condensation GO:0030261 15 15 0,000 0,05526556 0,07663989 ! hydrogen peroxide metabolic process GO:0042743 15 15 0,000 0,05526556 0,07658227 ! regulation of biomineral formation GO:0070167 15 15 0,000 0,05526556 0,07652473 GO:0030500|regulation of bone mineralization, ! regulation of production of molecular mediator of immune response GO:0002700 15 15 0,000 0,05526556 0,07646728 ! cyclic nucleotide biosynthetic process GO:0009190 15 15 0,000 0,05526556 0,07640992 ! cholesterol biosynthetic process GO:0006695 15 15 0,000 0,05526556 0,07635264 ! phospholipid transport GO:0015914 15 15 0,000 0,05526556 0,07629545 ! leukocyte homeostasis GO:0001776 15 15 0,000 0,05526556 0,07623834 ! regulation of cytokine secretion GO:0050707 15 15 0,000 0,05526556 0,07618132 ! glutathione metabolic process GO:0006749 16 15 0,000 0,05526556 0,07612438 ! nicotinamide metabolic process GO:0006769 15 15 0,000 0,05526556 0,07606753 GO:0046496|nicotinamide nucleotide metabolic process, ! positive regulation of B cell activation GO:0050871 15 15 0,000 0,05526556 0,07601076 ! positive regulation of myeloid cell differentiation GO:0045639 16 15 0,000 0,05526556 0,07595408 ! cellular alkene metabolic process GO:0043449 15 15 0,000 0,05526556 0,07589748 ! negative regulation of transcription factor activity GO:0043433 16 15 0,000 0,05526556 0,07584097 GO:0090048|negative regulation of transcription regulator activity, ! somatic diversification of immune receptors GO:0002200 15 15 0,000 0,05526556 0,07578454 ! protein homooligomerization GO:0051260 15 15 0,000 0,05526556 0,07572819 ! positive regulation of immune effector process GO:0002699 15 15 0,000 0,05526556 0,07567193 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 16 16 0,000 0,05884357 0,08051129 ! negative regulation of adenylate cyclase activity GO:0007194 16 16 0,000 0,05884357 0,08045156 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! alkaloid metabolic process GO:0009820 16 16 0,000 0,05884357 0,08039193 ! regulation of synaptic plasticity GO:0048167 16 16 0,000 0,05884357 0,08033238 ! spliceosomal snRNP biogenesis GO:0000387 16 16 0,000 0,05884357 0,08027291 ! learning GO:0007612 16 16 0,000 0,05884357 0,08021354 ! circadian rhythm GO:0007623 16 16 0,000 0,05884357 0,08015426 ! inner ear morphogenesis GO:0042472 16 16 0,000 0,05884357 0,08009506 ! positive regulation of mitosis GO:0045840 16 16 0,000 0,05884357 0,08003595 GO:0051785|positive regulation of nuclear division, ! vacuole organization GO:0007033 16 16 0,000 0,05884357 0,07997692 ! cellular response to reactive oxygen species GO:0034614 16 16 0,000 0,05884357 0,07991799 ! positive regulation of cytoskeleton organization GO:0051495 16 16 0,000 0,05884357 0,07985914 ! vesicle targeting GO:0006903 17 16 0,000 0,05884357 0,07980037 ! segmentation GO:0035282 17 16 0,000 0,05884357 0,0797417 ! triglyceride metabolic process GO:0006641 16 16 0,000 0,05884357 0,07968311 ! iron ion homeostasis GO:0055072 16 16 0,000 0,05884357 0,0796246 ! positive regulation of cell development GO:0010720 16 16 0,000 0,05884357 0,07956618 ! regulation of myeloid leukocyte differentiation GO:0002761 17 16 0,000 0,05884357 0,07950785 ! lymphocyte proliferation GO:0046651 16 16 0,000 0,05884357 0,0794496 ! regulation of systemic arterial blood pressure GO:0003073 17 16 0,000 0,05884357 0,07939144 ! pentose metabolic process GO:0019321 16 16 0,000 0,05884357 0,07933336 ! fatty acid transport GO:0015908 16 16 0,000 0,05884357 0,07927537 ! positive regulation of MAPKKK cascade GO:0043410 17 16 0,000 0,05884357 0,07921746 ! regulation of microtubule cytoskeleton organization GO:0070507 16 16 0,000 0,05884357 0,07915964 ! cofactor catabolic process GO:0051187 16 16 0,000 0,05884357 0,0791019 ! ethanolamine and derivative metabolic process GO:0042439 17 16 0,000 0,05884357 0,07904425 ! polyol metabolic process GO:0019751 16 16 0,000 0,05884357 0,07898668 ! serine family amino acid metabolic process GO:0009069 16 16 0,000 0,05884357 0,07892919 ! glutamine family amino acid catabolic process GO:0009065 17 16 0,000 0,05884357 0,07887179 ! porphyrin metabolic process GO:0006778 16 16 0,000 0,05884357 0,07881447 GO:0033013|tetrapyrrole metabolic process, ! embryonic epithelial tube formation GO:0001838 17 16 0,000 0,05884357 0,07875723 GO:0001841|neural tube formation, ! regulation of JUN kinase activity GO:0043506 17 16 0,000 0,05884357 0,07870008 GO:0043507|positive regulation of JUN kinase activity, ! regulation of cell morphogenesis involved in differentiation GO:0010769 17 16 0,000 0,05884357 0,07864301 ! response to xenobiotic stimulus GO:0009410 16 16 0,000 0,05884357 0,07858602 ! regulation of coagulation GO:0050818 17 16 0,000 0,05884357 0,07852911 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 17 17 0,000 0,06240856 0,08322647 ! regulation of actin filament depolymerization GO:0030834 17 17 0,000 0,06240856 0,08316629 ! phosphoinositide biosynthetic process GO:0046489 17 17 0,000 0,06240856 0,0831062 ! regulation of transmembrane transport GO:0034762 17 17 0,000 0,06240856 0,08304619 ! nucleotide-excision repair, DNA damage removal GO:0000718 18 17 0,000 0,06240856 0,08298628 ! leukocyte adhesion GO:0007159 17 17 0,000 0,06240856 0,08292644 ! dicarboxylic acid metabolic process GO:0043648 18 17 0,000 0,06240856 0,0828667 ! sensory perception of smell GO:0007608 17 17 0,000 0,06240856 0,08280704 ! glucose transport GO:0015758 17 17 0,000 0,06240856 0,08274747 ! cell junction assembly GO:0034329 18 17 0,000 0,06240856 0,08268798 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 17 17 0,000 0,06240856 0,08262858 ! cellular carbohydrate biosynthetic process GO:0034637 17 17 0,000 0,06240856 0,08256926 ! development of primary male sexual characteristics GO:0046546 17 17 0,000 0,06240856 0,08251003 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 17 17 0,000 0,06240856 0,08245088 ! neural crest cell development GO:0014032 19 17 0,000 0,06240856 0,08239182 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 18 17 0,000 0,06240856 0,08233284 ! immune response-activating signal transduction GO:0002757 17 17 0,000 0,06240856 0,08227395 GO:0002764|immune response-regulating signal transduction, ! cell recognition GO:0008037 18 17 0,000 0,06240856 0,08221514 ! positive regulation of protein secretion GO:0050714 17 17 0,000 0,06240856 0,08215641 ! pyridine nucleotide metabolic process GO:0019362 17 17 0,000 0,06240856 0,08209777 ! pigmentation GO:0043473 17 17 0,000 0,06240856 0,08203921 ! myeloid leukocyte activation GO:0002274 18 17 0,000 0,06240856 0,08198074 ! adult locomotory behavior GO:0008344 17 17 0,000 0,06240856 0,08192235 ! regulation of calcium ion transport GO:0051924 17 17 0,000 0,06240856 0,08186404 ! liver development GO:0001889 17 17 0,000 0,06240856 0,08180582 ! gene silencing GO:0016458 17 17 0,000 0,06240856 0,08174767 ! mRNA export from nucleus GO:0006406 18 18 0,000 0,06596056 0,086339 ! regulation of cell projection organization GO:0031344 19 18 0,000 0,06596056 0,08627772 ! icosanoid biosynthetic process GO:0046456 18 18 0,000 0,06596056 0,08621653 ! meiosis I GO:0007127 18 18 0,000 0,06596056 0,08615543 ! regulation of metal ion transport GO:0010959 18 18 0,000 0,06596056 0,08609441 ! membrane docking GO:0022406 18 18 0,000 0,06596056 0,08603348 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 18 18 0,000 0,06596056 0,08597264 ! mononuclear cell proliferation GO:0032943 18 18 0,000 0,06596056 0,08591188 GO:0070661|leukocyte proliferation, ! response to calcium ion GO:0051592 18 18 0,000 0,06596056 0,08585121 ! negative regulation of response to external stimulus GO:0032102 18 18 0,000 0,06596056 0,08579062 ! hexose transport GO:0008645 18 18 0,000 0,06596056 0,08573012 GO:0015749|monosaccharide transport, ! cholesterol homeostasis GO:0042632 18 18 0,000 0,06596056 0,08566971 GO:0055092|sterol homeostasis, ! striated muscle contraction GO:0006941 18 18 0,000 0,06596056 0,08560938 ! neutral lipid metabolic process GO:0006638 18 18 0,000 0,06596056 0,08554913 GO:0006639|acylglycerol metabolic process, ! negative regulation of DNA binding GO:0043392 19 18 0,000 0,06596056 0,08548897 ! ceramide metabolic process GO:0006672 18 18 0,000 0,06596056 0,08542889 GO:0046519|sphingoid metabolic process, ! ribonucleoside monophosphate metabolic process GO:0009161 18 18 0,000 0,06596056 0,0853689 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! negative regulation of MAP kinase activity GO:0043407 18 18 0,000 0,06596056 0,08530899 ! regulation of microtubule-based process GO:0032886 18 18 0,000 0,06596056 0,08524917 ! negative regulation of catabolic process GO:0009895 18 18 0,000 0,06596056 0,08518943 ! establishment of vesicle localization GO:0051650 19 18 0,000 0,06596056 0,08512977 ! activation of adenylate cyclase activity GO:0007190 19 19 0,000 0,06949962 0,08963457 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 19 19 0,000 0,06949962 0,08957189 GO:0006956|complement activation, ! glial cell differentiation GO:0010001 19 19 0,000 0,06949962 0,08950929 ! regulation of JAK-STAT cascade GO:0046425 19 19 0,000 0,06949962 0,08944679 ! feeding behavior GO:0007631 19 19 0,000 0,06949962 0,08938437 ! peroxisome organization GO:0007031 19 19 0,000 0,06949962 0,08932204 ! positive regulation of T cell proliferation GO:0042102 19 19 0,000 0,06949962 0,08925979 ! regulation of striated muscle tissue development GO:0016202 20 19 0,000 0,06949962 0,08919763 ! multicellular organismal metabolic process GO:0044236 19 19 0,000 0,06949962 0,08913556 ! ribonucleoside metabolic process GO:0009119 19 19 0,000 0,06949962 0,08907357 ! cellular response to oxidative stress GO:0034599 19 19 0,000 0,06949962 0,08901167 ! regulation of lymphocyte mediated immunity GO:0002706 19 19 0,000 0,06949962 0,08894986 ! positive regulation of T cell differentiation GO:0045582 19 19 0,000 0,06949962 0,08888813 ! nuclear-transcribed mRNA catabolic process GO:0000956 19 19 0,000 0,06949962 0,08882649 ! regulation of protein stability GO:0031647 19 19 0,000 0,06949962 0,08876493 ! hormone biosynthetic process GO:0042446 19 19 0,000 0,06949962 0,08870346 ! biogenic amine biosynthetic process GO:0042401 20 19 0,000 0,06949962 0,08864208 ! placenta development GO:0001890 19 19 0,000 0,06949962 0,08858077 ! response to heat GO:0009408 19 19 0,000 0,06949962 0,08851956 ! vesicle localization GO:0051648 20 19 0,000 0,06949962 0,08845843 ! regulation of muscle development GO:0048634 21 20 0,000 0,07302578 0,09288235 ! establishment or maintenance of cell polarity GO:0007163 21 20 0,000 0,07302578 0,09281829 ! negative regulation of binding GO:0051100 21 20 0,000 0,07302578 0,09275432 ! organic ether metabolic process GO:0018904 20 20 0,000 0,07302578 0,09269044 GO:0006662|glycerol ether metabolic process, ! cytoskeleton-dependent intracellular transport GO:0030705 20 20 0,000 0,07302578 0,09262665 ! phagocytosis GO:0006909 21 20 0,000 0,07302578 0,09256294 ! unsaturated fatty acid biosynthetic process GO:0006636 20 20 0,000 0,07302578 0,09249933 ! protein targeting to membrane GO:0006612 22 20 0,000 0,07302578 0,0924358 ! cyclic nucleotide metabolic process GO:0009187 20 20 0,000 0,07302578 0,09237235 ! chromatin remodeling GO:0006338 20 20 0,000 0,07302578 0,092309 ! detection of abiotic stimulus GO:0009582 21 20 0,000 0,07302578 0,09224573 ! female gamete generation GO:0007292 20 20 0,000 0,07302578 0,09218255 ! negative regulation of neuron apoptosis GO:0043524 21 20 0,000 0,07302578 0,09211945 ! RNA modification GO:0009451 20 20 0,000 0,07302578 0,09205644 ! single fertilization GO:0007338 21 20 0,000 0,07302578 0,09199352 ! regulation of B cell activation GO:0050864 20 20 0,000 0,07302578 0,09193068 ! mitotic sister chromatid segregation GO:0000070 21 21 0,000 0,0765391 0,09628775 ! mRNA catabolic process GO:0006402 21 21 0,000 0,0765391 0,09622207 ! positive regulation of adenylate cyclase activity GO:0045762 21 21 0,000 0,0765391 0,09615648 GO:0051349|positive regulation of lyase activity, GO:0031281|positive regulation of cyclase activity, ! receptor-mediated endocytosis GO:0006898 21 21 0,000 0,0765391 0,09609098 ! Notch signaling pathway GO:0007219 22 21 0,000 0,0765391 0,09602557 ! morphogenesis of embryonic epithelium GO:0016331 22 21 0,000 0,0765391 0,09596024 ! ear morphogenesis GO:0042471 21 21 0,000 0,0765391 0,09589501 ! organic anion transport GO:0015711 21 21 0,000 0,0765391 0,09582986 ! cholesterol transport GO:0030301 21 21 0,000 0,0765391 0,0957648 GO:0015918|sterol transport, ! spliceosome assembly GO:0000245 22 21 0,000 0,0765391 0,09569983 ! regulation of Rab protein signal transduction GO:0032483 21 21 0,000 0,0765391 0,09563495 GO:0032313|regulation of Rab GTPase activity, ! regulation of leukocyte mediated immunity GO:0002703 21 21 0,000 0,0765391 0,09557016 ! regulation of multicellular organism growth GO:0040014 21 21 0,000 0,0765391 0,09550545 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 21 21 0,000 0,0765391 0,09544084 ! regulation of proteolysis GO:0030162 21 21 0,000 0,0765391 0,09537631 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 21 21 0,000 0,0765391 0,09531186 ! positive regulation of transcription factor activity GO:0051091 22 22 0,000 0,08003961 0,09960364 GO:0090047|positive regulation of transcription regulator activity, ! RNA export from nucleus GO:0006405 22 22 0,000 0,08003961 0,09953643 ! sister chromatid segregation GO:0000819 22 22 0,000 0,08003961 0,09946931 ! cellular amide metabolic process GO:0043603 22 22 0,000 0,08003961 0,09940229 ! regulation of ion transport GO:0043269 22 22 0,000 0,08003961 0,09933535 ! cell junction organization GO:0034330 23 22 0,000 0,08003961 0,0992685 ! positive regulation of lymphocyte proliferation GO:0050671 22 22 0,000 0,08003961 0,09920174 GO:0032946|positive regulation of mononuclear cell proliferation, GO:0070665|positive regulation of leukocyte proliferation, GO:0070668|positive regulation of mast cell proliferation, ! maintenance of protein location in cell GO:0032507 23 22 0,000 0,08003961 0,09913508 ! spindle organization GO:0007051 22 22 0,000 0,08003961 0,0990685 ! pigment biosynthetic process GO:0046148 22 22 0,000 0,08003961 0,09900201 ! cell chemotaxis GO:0060326 23 22 0,000 0,08003961 0,09893561 GO:0030595|leukocyte chemotaxis, ! respiratory gaseous exchange GO:0007585 22 22 0,000 0,08003961 0,0988693 ! erythrocyte differentiation GO:0030218 23 22 0,000 0,08003961 0,09880308 ! male sex differentiation GO:0046661 22 22 0,000 0,08003961 0,09873694 ! sterol biosynthetic process GO:0016126 22 22 0,000 0,08003961 0,0986709 ! biopolymer methylation GO:0043414 22 22 0,000 0,08003961 0,09860494 GO:0032259|methylation, ! regulation of adaptive immune response GO:0002819 22 22 0,000 0,08003961 0,09853907 ! detection of external stimulus GO:0009581 23 22 0,000 0,08003961 0,09847329 ! neuron migration GO:0001764 22 22 0,000 0,08003961 0,0984076 ! regulation of Wnt receptor signaling pathway GO:0030111 23 22 0,000 0,08003961 0,098342 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 22 22 0,000 0,08003961 0,09827648 ! positive regulation of lymphocyte differentiation GO:0045621 22 22 0,000 0,08003961 0,09821105 ! aerobic respiration GO:0009060 22 22 0,000 0,08003961 0,0981457 ! cytokine production GO:0001816 22 22 0,000 0,08003961 0,09808045 ! cytokinesis GO:0000910 23 22 0,000 0,08003961 0,09801528 ! pyrimidine nucleotide metabolic process GO:0006220 22 22 0,000 0,08003961 0,09795019 ! response to hydrogen peroxide GO:0042542 24 23 0,000 0,08352735 0,10215057 ! epithelial cell differentiation GO:0030855 23 23 0,000 0,08352735 0,10208283 ! viral infectious cycle GO:0019058 23 23 0,000 0,08352735 0,10201518 ! regulation of hormone secretion GO:0046883 23 23 0,000 0,08352735 0,10194762 ! negative regulation of protein complex disassembly GO:0043242 23 23 0,000 0,08352735 0,10188015 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 23 23 0,000 0,08352735 0,10181277 ! induction of apoptosis by extracellular signals GO:0008624 23 23 0,000 0,08352735 0,10174548 ! regulation of ARF protein signal transduction GO:0032012 23 23 0,000 0,08352735 0,10167828 ! endocrine system development GO:0035270 23 23 0,000 0,08352735 0,10161116 ! lipid homeostasis GO:0055088 23 23 0,000 0,08352735 0,10154414 ! Rho protein signal transduction GO:0007266 24 23 0,000 0,08352735 0,1014772 ! regulation of JNK cascade GO:0046328 25 23 0,000 0,08352735 0,10141035 ! cell projection assembly GO:0030031 25 23 0,000 0,08352735 0,10134359 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 26 24 0,000 0,08700238 0,10549039 ! cellular amino acid biosynthetic process GO:0008652 24 24 0,000 0,08700238 0,10542103 ! heterocycle biosynthetic process GO:0018130 24 24 0,000 0,08700238 0,10535177 ! nucleotide catabolic process GO:0009166 24 24 0,000 0,08700238 0,1052826 ! erythrocyte homeostasis GO:0034101 25 24 0,000 0,08700238 0,10521351 ! fertilization GO:0009566 25 24 0,000 0,08700238 0,10514452 ! maintenance of protein location GO:0045185 25 24 0,000 0,08700238 0,10507562 ! oxidoreduction coenzyme metabolic process GO:0006733 24 24 0,000 0,08700238 0,10500681 ! androgen receptor signaling pathway GO:0030521 24 24 0,000 0,08700238 0,10493808 ! regulation of actin filament polymerization GO:0030833 25 25 0,000 0,09046474 0,10904285 ! negative regulation of secretion GO:0051048 26 25 0,000 0,09046474 0,10897158 ! protein amino acid N-linked glycosylation GO:0006487 25 25 0,000 0,09046474 0,10890041 ! sensory perception of chemical stimulus GO:0007606 25 25 0,000 0,09046474 0,10882932 ! cellular component disassembly GO:0022411 26 25 0,000 0,09046474 0,10875833 ! endosome transport GO:0016197 25 25 0,000 0,09046474 0,10868743 ! polysaccharide biosynthetic process GO:0000271 25 25 0,000 0,09046474 0,10861663 ! excretion GO:0007588 25 25 0,000 0,09046474 0,10854591 ! positive regulation of DNA binding GO:0043388 26 25 0,000 0,09046474 0,10847529 ! generation of a signal involved in cell-cell signaling GO:0003001 27 25 0,000 0,09046474 0,10840476 ! icosanoid metabolic process GO:0006690 25 25 0,000 0,09046474 0,10833432 ! regulation of endocytosis GO:0030100 25 25 0,000 0,09046474 0,10826398 ! JAK-STAT cascade GO:0007259 26 25 0,000 0,09046474 0,10819372 ! positive regulation of cytokine production GO:0001819 25 25 0,000 0,09046474 0,10812356 ! positive regulation of binding GO:0051099 27 26 0,000 0,09391448 0,11217393 ! positive regulation of defense response GO:0031349 26 26 0,000 0,09391448 0,11210128 ! glycolysis GO:0006096 26 26 0,000 0,09391448 0,11202872 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 26 26 0,000 0,09391448 0,11195626 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 26 26 0,000 0,09391448 0,11188389 ! negative regulation of cell migration GO:0030336 26 26 0,000 0,09391448 0,11181161 ! cellular defense response GO:0006968 26 26 0,000 0,09391448 0,11173943 ! positive regulation of cytokine biosynthetic process GO:0042108 26 26 0,000 0,09391448 0,11166734 ! regulation of protein secretion GO:0050708 26 26 0,000 0,09391448 0,11159534 ! germ cell development GO:0007281 27 26 0,000 0,09391448 0,11152344 ! regulation of blood vessel size GO:0050880 27 26 0,000 0,09391448 0,11145163 GO:0035150|regulation of tube size, ! pigment metabolic process GO:0042440 26 26 0,000 0,09391448 0,11137991 ! maintenance of location in cell GO:0051651 27 26 0,000 0,09391448 0,11130828 ! chloride transport GO:0006821 27 27 0,000 0,09735163 0,11530787 ! regulation of neurotransmitter levels GO:0001505 31 27 0,000 0,09735163 0,11523381 ! learning or memory GO:0007611 28 27 0,000 0,09735163 0,11515985 ! monocarboxylic acid transport GO:0015718 27 27 0,000 0,09735163 0,11508598 ! cAMP-mediated signaling GO:0019933 27 27 0,000 0,09735163 0,11501221 ! peptide metabolic process GO:0006518 29 27 0,000 0,09735163 0,11493853 ! mesenchymal cell development GO:0014031 29 27 0,000 0,09735163 0,11486495 GO:0060485|mesenchyme development, GO:0048762|mesenchymal cell differentiation, ! inner ear development GO:0048839 27 27 0,000 0,09735163 0,11479146 ! defense response to bacterium GO:0042742 27 27 0,000 0,09735163 0,11471806 ! isoprenoid metabolic process GO:0006720 27 27 0,000 0,09735163 0,11464476 ! glutamine family amino acid metabolic process GO:0009064 28 27 0,000 0,09735163 0,11457155 ! cell growth GO:0016049 27 27 0,000 0,09735163 0,11449843 ! tRNA aminoacylation for protein translation GO:0006418 28 28 0,000 0,10077624 0,11845064 GO:0043038|amino acid activation, GO:0043039|tRNA aminoacylation, ! stress-activated protein kinase signaling pathway GO:0031098 28 28 0,000 0,10077624 0,11837515 GO:0007254|JNK cascade, ! neuromuscular process GO:0050905 28 28 0,000 0,10077624 0,11829975 ! carbohydrate transport GO:0008643 28 28 0,000 0,10077624 0,11822445 ! regulation of muscle contraction GO:0006937 28 28 0,000 0,10077624 0,11814924 ! unsaturated fatty acid metabolic process GO:0033559 28 28 0,000 0,10077624 0,11807413 ! sulfur compound biosynthetic process GO:0044272 28 28 0,000 0,10077624 0,11799911 ! keratinocyte differentiation GO:0030216 28 28 0,000 0,10077624 0,11792419 ! histone modification GO:0016570 28 28 0,000 0,10077624 0,11784937 ! cartilage development GO:0051216 29 28 0,000 0,10077624 0,11777464 ! glycerophospholipid biosynthetic process GO:0046474 30 29 0,000 0,10418835 0,12168513 ! phosphoinositide metabolic process GO:0030384 29 29 0,000 0,10418835 0,12160806 ! leukocyte migration GO:0050900 30 29 0,000 0,10418835 0,1215311 ! antigen processing and presentation GO:0019882 29 29 0,000 0,10418835 0,12145423 ! DNA-dependent DNA replication GO:0006261 29 29 0,000 0,10418835 0,12137745 ! tRNA processing GO:0008033 29 29 0,000 0,10418835 0,12130078 ! regulation of gene expression, epigenetic GO:0040029 29 29 0,000 0,10418835 0,1212242 ! covalent chromatin modification GO:0016569 29 29 0,000 0,10418835 0,12114772 ! adult behavior GO:0030534 30 29 0,000 0,10418835 0,12107133 ! regulation of protein polymerization GO:0032271 29 29 0,000 0,10418835 0,12099504 ! transition metal ion transport GO:0000041 31 30 0,000 0,10758802 0,12486443 ! RNA catabolic process GO:0006401 30 30 0,000 0,10758802 0,12478585 ! response to reactive oxygen species GO:0000302 31 30 0,000 0,10758802 0,12470737 ! ER to Golgi vesicle-mediated transport GO:0006888 30 30 0,000 0,10758802 0,12462899 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 30 30 0,000 0,10758802 0,1245507 ! neuropeptide signaling pathway GO:0007218 30 30 0,000 0,10758802 0,12447251 ! regulation of protein complex disassembly GO:0043244 30 30 0,000 0,10758802 0,12439443 ! positive regulation of protein amino acid phosphorylation GO:0001934 30 30 0,000 0,10758802 0,12431644 ! response to temperature stimulus GO:0009266 30 30 0,000 0,10758802 0,12423854 ! immunoglobulin mediated immune response GO:0016064 30 30 0,000 0,10758802 0,12416075 GO:0019724|B cell mediated immunity, ! regulation of inflammatory response GO:0050727 30 30 0,000 0,10758802 0,12408305 ! water-soluble vitamin metabolic process GO:0006767 30 30 0,000 0,10758802 0,12400545 ! vesicle organization GO:0016050 30 30 0,000 0,10758802 0,12392795 ! cellular amino acid derivative biosynthetic process GO:0042398 31 30 0,000 0,10758802 0,12385054 ! establishment of organelle localization GO:0051656 31 30 0,000 0,10758802 0,12377323 ! regulation of translational initiation GO:0006446 31 31 0,000 0,11097527 0,12759041 ! membrane fusion GO:0006944 31 31 0,000 0,11097527 0,12751087 ! negative regulation of cytoskeleton organization GO:0051494 32 31 0,000 0,11097527 0,12743142 ! ion transmembrane transport GO:0034220 31 31 0,000 0,11097527 0,12735207 GO:0015985|energy coupled proton transport, down electrochemical gradient, GO:0015986|ATP synthesis coupled proton transport, ! glycerolipid biosynthetic process GO:0045017 32 31 0,000 0,11097527 0,12727283 ! digestion GO:0007586 31 31 0,000 0,11097527 0,12719368 ! nucleoside metabolic process GO:0009116 31 31 0,000 0,11097527 0,12711462 ! regulation of heart contraction GO:0008016 31 31 0,000 0,11097527 0,12703567 ! sphingolipid metabolic process GO:0006665 31 31 0,000 0,11097527 0,12695682 ! extracellular matrix organization GO:0030198 31 31 0,000 0,11097527 0,12687806 ! ribonucleoprotein complex assembly GO:0022618 32 31 0,000 0,11097527 0,1267994 ! epidermal cell differentiation GO:0009913 31 31 0,000 0,11097527 0,12672084 ! regulation of myeloid cell differentiation GO:0045637 32 31 0,000 0,11097527 0,12664237 ! negative regulation of cell motion GO:0051271 31 31 0,000 0,11097527 0,126564 ! cell redox homeostasis GO:0045454 32 32 0,000 0,11435017 0,13033232 ! glucose catabolic process GO:0006007 32 32 0,000 0,11435017 0,13025177 ! glycosaminoglycan metabolic process GO:0030203 34 32 0,000 0,11435017 0,13017131 ! regulation of vesicle-mediated transport GO:0060627 33 32 0,000 0,11435017 0,13009096 ! cell maturation GO:0048469 32 32 0,000 0,11435017 0,13001071 ! nuclear export GO:0051168 32 32 0,000 0,11435017 0,12993055 ! protein maturation by peptide bond cleavage GO:0051605 32 32 0,000 0,11435017 0,1298505 ! maintenance of location GO:0051235 33 32 0,000 0,11435017 0,12977054 ! regulation of cellular response to stress GO:0080135 35 33 0,000 0,11771274 0,13350436 ! amino acid transport GO:0006865 33 33 0,000 0,11771274 0,13342225 ! activation of protein kinase activity GO:0032147 35 33 0,000 0,11771274 0,13334025 ! regulation of protein complex assembly GO:0043254 33 33 0,000 0,11771274 0,13325834 ! membrane lipid metabolic process GO:0006643 33 33 0,000 0,11771274 0,13317654 ! regulation of actin polymerization or depolymerization GO:0008064 33 33 0,000 0,11771274 0,13309483 ! regulation of synaptic transmission GO:0050804 33 33 0,000 0,11771274 0,13301323 ! regulation of actin filament length GO:0030832 34 34 0,000 0,12106303 0,13671518 ! response to metal ion GO:0010038 34 34 0,000 0,12106303 0,13663146 ! ear development GO:0043583 34 34 0,000 0,12106303 0,13654784 ! muscle cell differentiation GO:0042692 35 34 0,000 0,12106303 0,13646433 ! coenzyme biosynthetic process GO:0009108 34 34 0,000 0,12106303 0,13638091 ! nucleoside monophosphate biosynthetic process GO:0009124 34 34 0,000 0,12106303 0,1362976 ! regulation of lipid metabolic process GO:0019216 34 34 0,000 0,12106303 0,13621439 ! secondary metabolic process GO:0019748 34 34 0,000 0,12106303 0,13613128 ! negative regulation of response to stimulus GO:0048585 34 34 0,000 0,12106303 0,13604828 ! detection of stimulus GO:0051606 36 34 0,000 0,12106303 0,13596537 ! acute inflammatory response GO:0002526 35 35 0,000 0,12440109 0,13962924 ! regulation of cellular component size GO:0032535 35 35 0,000 0,12440109 0,13954426 ! regulation of cytokine biosynthetic process GO:0042035 35 35 0,000 0,12440109 0,13945938 ! inorganic anion transport GO:0015698 35 35 0,000 0,12440109 0,1393746 ! regulation of immune effector process GO:0002697 35 35 0,000 0,12440109 0,13928993 ! hydrogen transport GO:0006818 36 36 0,000 0,12772696 0,14292701 GO:0015992|proton transport, ! response to inorganic substance GO:0010035 36 36 0,000 0,12772696 0,14284029 ! aminoglycan metabolic process GO:0006022 38 36 0,000 0,12772696 0,14275367 ! oxygen and reactive oxygen species metabolic process GO:0006800 37 36 0,000 0,12772696 0,14266715 ! regulation of mitosis GO:0007088 37 36 0,000 0,12772696 0,14258074 GO:0051783|regulation of nuclear division, ! female pregnancy GO:0007565 37 36 0,000 0,12772696 0,14249443 ! RNA elongation from RNA polymerase II promoter GO:0006368 36 36 0,000 0,12772696 0,14240822 ! positive regulation of organelle organization GO:0010638 36 36 0,000 0,12772696 0,14232212 ! heterocycle catabolic process GO:0046700 36 36 0,000 0,12772696 0,14223613 ! integrin-mediated signaling pathway GO:0007229 36 36 0,000 0,12772696 0,14215024 ! regulation of transmission of nerve impulse GO:0051969 36 36 0,000 0,12772696 0,14206445 ! activation of immune response GO:0002253 36 36 0,000 0,12772696 0,14197877 ! coagulation GO:0050817 39 36 0,000 0,12772696 0,14189318 GO:0007596|blood coagulation, ! regulation of adenylate cyclase activity GO:0045761 37 37 0,000 0,13104068 0,14548673 GO:0031279|regulation of cyclase activity, GO:0051339|regulation of lyase activity, ! regulation of transcription factor activity GO:0051090 38 37 0,000 0,13104068 0,14539914 GO:0090046|regulation of transcription regulator activity, ! meiosis GO:0007126 37 37 0,000 0,13104068 0,14531166 GO:0051327|M phase of meiotic cell cycle, ! lymphocyte mediated immunity GO:0002449 37 37 0,000 0,13104068 0,14522428 ! ATP synthesis coupled electron transport GO:0042773 37 37 0,000 0,13104068 0,14513701 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! cellular amino acid catabolic process GO:0009063 38 37 0,000 0,13104068 0,14504984 ! regulation of Rho protein signal transduction GO:0035023 37 37 0,000 0,13104068 0,14496277 ! positive regulation of secretion GO:0051047 39 38 0,000 0,1343423 0,14852601 ! neurotransmitter transport GO:0006836 40 38 0,000 0,1343423 0,14843696 ! cellular hormone metabolic process GO:0034754 39 38 0,000 0,1343423 0,14834802 ! exocytosis GO:0006887 40 38 0,000 0,1343423 0,14825919 ! cell-matrix adhesion GO:0007160 39 38 0,000 0,1343423 0,14817047 ! chromosome segregation GO:0007059 38 38 0,000 0,1343423 0,14808185 ! hexose catabolic process GO:0019320 38 38 0,000 0,1343423 0,14799334 ! RNA elongation GO:0006354 38 38 0,000 0,1343423 0,14790493 ! meiotic cell cycle GO:0051321 38 38 0,000 0,1343423 0,14781663 ! regulation of neurological system process GO:0031644 38 38 0,000 0,1343423 0,14772843 ! steroid hormone receptor signaling pathway GO:0030518 38 38 0,000 0,1343423 0,14764034 ! regulation of cAMP biosynthetic process GO:0030817 39 39 0,000 0,13763185 0,15116537 ! hemostasis GO:0007599 42 39 0,000 0,13763185 0,15107534 ! positive regulation of protein modification process GO:0031401 39 39 0,000 0,13763185 0,15098541 ! response to unfolded protein GO:0006986 39 39 0,000 0,13763185 0,15089559 ! nucleoside monophosphate metabolic process GO:0009123 39 39 0,000 0,13763185 0,15080588 ! fatty acid biosynthetic process GO:0006633 39 39 0,000 0,13763185 0,15071628 ! cytokine-mediated signaling pathway GO:0019221 39 39 0,000 0,13763185 0,15062678 ! intracellular protein transmembrane transport GO:0065002 39 39 0,000 0,13763185 0,15053739 ! positive regulation of T cell activation GO:0050870 39 39 0,000 0,13763185 0,1504481 ! developmental maturation GO:0021700 39 39 0,000 0,13763185 0,15035892 ! DNA catabolic process GO:0006308 41 40 0,000 0,14090938 0,15384833 ! intracellular receptor-mediated signaling pathway GO:0030522 40 40 0,000 0,14090938 0,15375724 ! myeloid cell differentiation GO:0030099 42 40 0,000 0,14090938 0,15366626 ! organelle localization GO:0051640 41 40 0,000 0,14090938 0,15357539 ! regulation of nucleotide biosynthetic process GO:0030808 41 41 0,000 0,14417492 0,1570416 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! amine catabolic process GO:0009310 42 41 0,000 0,14417492 0,15694884 ! elevation of cytosolic calcium ion concentration GO:0007204 41 41 0,000 0,14417492 0,15685619 ! phospholipid biosynthetic process GO:0008654 42 41 0,000 0,14417492 0,15676365 ! leukocyte mediated immunity GO:0002443 41 41 0,000 0,14417492 0,15667122 ! regulation of Ras GTPase activity GO:0032318 41 41 0,000 0,14417492 0,1565789 ! monosaccharide catabolic process GO:0046365 41 41 0,000 0,14417492 0,15648668 ! respiratory electron transport chain GO:0022904 43 42 0,000 0,14742854 0,15992395 ! cytosolic calcium ion homeostasis GO:0051480 42 42 0,000 0,14742854 0,15982988 ! cell-substrate adhesion GO:0031589 43 42 0,000 0,14742854 0,15973592 ! negative regulation of ligase activity GO:0051352 43 42 0,000 0,14742854 0,15964206 GO:0051444|negative regulation of ubiquitin-protein ligase activity, GO:0051436|negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle, ! response to protein stimulus GO:0051789 42 42 0,000 0,14742854 0,15954832 ! one-carbon metabolic process GO:0006730 42 42 0,000 0,14742854 0,15945469 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 42 42 0,000 0,14742854 0,15936117 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 43 43 0,000 0,15067025 0,1627698 ! alcohol catabolic process GO:0046164 43 43 0,000 0,15067025 0,16267444 ! homeostasis of number of cells GO:0048872 44 43 0,000 0,15067025 0,1625792 ! humoral immune response GO:0006959 44 44 0,000 0,15390012 0,16596718 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 45 44 0,000 0,15390012 0,16587013 ! mRNA transport GO:0051028 44 44 0,000 0,15390012 0,16577318 ! negative regulation of organelle organization GO:0010639 45 44 0,000 0,15390012 0,16567635 ! vitamin metabolic process GO:0006766 44 44 0,000 0,15390012 0,16557963 ! positive regulation of lymphocyte activation GO:0051251 44 44 0,000 0,15390012 0,16548303 ! amine biosynthetic process GO:0009309 46 45 0,000 0,15711817 0,16884477 ! homophilic cell adhesion GO:0007156 45 45 0,000 0,15711817 0,16874638 ! regulation of actin cytoskeleton organization GO:0032956 46 45 0,000 0,15711817 0,1686481 ! regulation of DNA binding GO:0051101 47 45 0,000 0,15711817 0,16854993 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 46 45 0,000 0,15711817 0,16845188 ! steroid biosynthetic process GO:0006694 46 45 0,000 0,15711817 0,16835394 ! regulation of actin filament-based process GO:0032970 47 46 0,000 0,16032445 0,17168969 ! cyclic-nucleotide-mediated signaling GO:0019935 46 46 0,000 0,16032445 0,17158999 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 47 46 0,000 0,16032445 0,1714904 ! transcription initiation from RNA polymerase II promoter GO:0006367 46 46 0,000 0,16032445 0,17139093 ! positive regulation of ligase activity GO:0051351 47 46 0,000 0,16032445 0,17129157 ! regulation of blood pressure GO:0008217 48 47 0,000 0,163519 0,17460343 ! amine transport GO:0015837 47 47 0,000 0,163519 0,17450232 ! calcium ion transport GO:0006816 48 48 0,000 0,16670186 0,17779603 ! actin filament organization GO:0007015 50 48 0,000 0,16670186 0,17769319 ! regulation of ubiquitin-protein ligase activity GO:0051438 49 48 0,000 0,16670186 0,17759048 ! regulation of cell cycle process GO:0010564 50 48 0,000 0,16670186 0,17748789 ! glycerophospholipid metabolic process GO:0006650 49 48 0,000 0,16670186 0,17738541 ! DNA recombination GO:0006310 48 48 0,000 0,16670186 0,17728305 ! divalent metal ion transport GO:0070838 49 49 0,000 0,16987308 0,18055138 ! response to nutrient GO:0007584 49 49 0,000 0,16987308 0,18044731 ! response to bacterium GO:0009617 50 49 0,000 0,16987308 0,18034337 ! regulation of ligase activity GO:0051340 50 49 0,000 0,16987308 0,18023954 ! cofactor biosynthetic process GO:0051188 49 49 0,000 0,16987308 0,18013584 ! positive regulation of cell activation GO:0050867 49 49 0,000 0,16987308 0,18003225 GO:0002696|positive regulation of leukocyte activation, ! regulation of defense response GO:0031347 50 50 0,000 0,17303269 0,18327543 ! chromatin assembly GO:0031497 50 50 0,000 0,17303269 0,18317016 GO:0006334|nucleosome assembly, ! RNA transport GO:0050658 50 50 0,000 0,17303269 0,18306501 GO:0050657|nucleic acid transport, GO:0051236|establishment of RNA localization, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 50 50 0,000 0,17303269 0,18295998 ! nitrogen compound catabolic process GO:0044270 51 50 0,000 0,17303269 0,18285507 ! transcription initiation GO:0006352 50 50 0,000 0,17303269 0,18275028 ! biogenic amine metabolic process GO:0006576 52 51 0,000 0,17618074 0,18596855 ! positive regulation of immune response GO:0050778 51 51 0,000 0,17618074 0,1858621 ! rRNA metabolic process GO:0016072 51 51 0,000 0,17618074 0,18575578 GO:0006364|rRNA processing, ! protein-DNA complex assembly GO:0065004 51 51 0,000 0,17618074 0,18564957 ! ATP biosynthetic process GO:0006754 51 51 0,000 0,17618074 0,18554348 ! RNA localization GO:0006403 52 52 0,000 0,17931726 0,18873884 ! cholesterol metabolic process GO:0008203 52 52 0,000 0,17931726 0,18863111 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 52 52 0,000 0,17931726 0,1885235 ! regulation of GTPase activity GO:0043087 53 52 0,000 0,17931726 0,18841602 ! regulation of body fluid levels GO:0050878 55 52 0,000 0,17931726 0,18830866 ! sodium ion transport GO:0006814 53 53 0,000 0,18244229 0,19148129 ! tRNA metabolic process GO:0006399 53 53 0,000 0,18244229 0,19137231 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 53 53 0,000 0,18244229 0,19126345 ! carbohydrate catabolic process GO:0016052 53 53 0,000 0,18244229 0,19115472 ! protein amino acid dephosphorylation GO:0006470 55 54 0,000 0,18555589 0,19430653 ! response to virus GO:0009615 54 54 0,000 0,18555589 0,19419619 ! hormone metabolic process GO:0042445 55 54 0,000 0,18555589 0,19408598 ! sulfur metabolic process GO:0006790 55 54 0,000 0,18555589 0,19397589 ! nucleosome organization GO:0034728 55 55 0,000 0,18865808 0,19710705 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 55 55 0,000 0,18865808 0,19699537 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! microtubule cytoskeleton organization GO:0000226 55 55 0,000 0,18865808 0,19688382 ! ribonucleoside triphosphate biosynthetic process GO:0009201 56 56 0,000 0,1917489 0,19999617 ! regulation of binding GO:0051098 60 57 0,000 0,1948284 0,20309318 ! ATP metabolic process GO:0046034 57 57 0,000 0,1948284 0,20297838 ! nucleoside triphosphate biosynthetic process GO:0009142 57 57 0,000 0,1948284 0,2028637 ! innate immune response GO:0045087 58 58 0,000 0,19789662 0,20594211 ! dephosphorylation GO:0016311 60 59 0,000 0,2009536 0,20900535 ! carboxylic acid transport GO:0046942 59 59 0,000 0,2009536 0,20888747 GO:0015849|organic acid transport, ! sterol metabolic process GO:0016125 59 59 0,000 0,2009536 0,20876972 ! cellular aromatic compound metabolic process GO:0006725 60 59 0,000 0,2009536 0,2086521 ! immune effector process GO:0002252 59 59 0,000 0,2009536 0,20853462 ! potassium ion transport GO:0006813 60 60 0,000 0,20399937 0,21157616 ! negative regulation of cellular protein metabolic process GO:0032269 60 60 0,000 0,20399937 0,21145717 ! cellular respiration GO:0045333 62 61 0,000 0,20703398 0,21448208 ! proteasomal protein catabolic process GO:0010498 62 61 0,000 0,20703398 0,21436159 GO:0043161|proteasomal ubiquitin-dependent protein catabolic process, ! positive regulation of cellular protein metabolic process GO:0032270 61 61 0,000 0,20703398 0,21424122 ! lipid transport GO:0006869 62 62 0,000 0,21005746 0,21724798 ! purine ribonucleoside triphosphate metabolic process GO:0009205 62 62 0,000 0,21005746 0,21712613 ! di-, tri-valent inorganic cation transport GO:0015674 63 62 0,000 0,21005746 0,21700443 ! regulation of secretion GO:0051046 65 63 0,000 0,21306985 0,21999313 ! ribonucleoside triphosphate metabolic process GO:0009199 63 63 0,000 0,21306985 0,21986996 ! purine nucleoside triphosphate metabolic process GO:0009144 63 63 0,000 0,21306985 0,21974692 ! glycerolipid metabolic process GO:0046486 65 64 0,000 0,2160712 0,22271769 ! regulation of cytoskeleton organization GO:0051493 66 64 0,000 0,2160712 0,22259319 ! anion transport GO:0006820 65 65 0,000 0,21906154 0,22554772 ! positive regulation of cellular component organization GO:0051130 65 65 0,000 0,21906154 0,22542179 ! regulation of hormone levels GO:0010817 66 65 0,000 0,21906154 0,22529599 ! protein amino acid glycosylation GO:0006486 66 66 0,000 0,22204091 0,22823279 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! nucleoside triphosphate metabolic process GO:0009141 66 66 0,000 0,22204091 0,22810557 ! DNA packaging GO:0006323 66 66 0,000 0,22204091 0,22797849 ! negative regulation of protein metabolic process GO:0051248 66 66 0,000 0,22204091 0,22785156 ! Golgi vesicle transport GO:0048193 67 67 0,000 0,22500935 0,23076918 ! muscle contraction GO:0006936 67 67 0,000 0,22500935 0,23064084 ! Ras protein signal transduction GO:0007265 69 67 0,000 0,22500935 0,23051263 ! purine ribonucleotide biosynthetic process GO:0009152 68 68 0,000 0,22796689 0,23341277 ! chromatin assembly or disassembly GO:0006333 68 68 0,000 0,22796689 0,23328317 ! regulation of translation GO:0006417 69 69 0,000 0,23091358 0,23616744 ! sensory perception of sound GO:0007605 71 69 0,000 0,23091358 0,23603646 GO:0050954|sensory perception of mechanical stimulus, ! carboxylic acid biosynthetic process GO:0046394 70 70 0,000 0,23384946 0,23890496 GO:0016053|organic acid biosynthetic process, ! translational elongation GO:0006414 71 71 0,000 0,23677456 0,24175928 ! oxidative phosphorylation GO:0006119 71 71 0,000 0,23677456 0,24162542 ! calcium ion homeostasis GO:0055074 71 71 0,000 0,23677456 0,2414917 GO:0006874|cellular calcium ion homeostasis, ! ribosome biogenesis GO:0042254 71 71 0,000 0,23677456 0,24135813 ! negative regulation of signal transduction GO:0009968 71 71 0,000 0,23677456 0,24122471 ! secretion by cell GO:0032940 75 72 0,000 0,23968891 0,24405893 ! muscle system process GO:0003012 72 72 0,000 0,23968891 0,24392417 ! regulation of cytokine production GO:0001817 72 72 0,000 0,23968891 0,24378955 ! electron transport chain GO:0022900 75 74 0,000 0,24548556 0,24954765 ! coenzyme metabolic process GO:0006732 75 74 0,000 0,24548556 0,24941008 ! ribonucleotide biosynthetic process GO:0009260 75 75 0,000 0,24836793 0,2521995 ! purine ribonucleotide metabolic process GO:0009150 75 75 0,000 0,24836793 0,25206062 ! negative regulation of cell communication GO:0010648 76 76 0,000 0,2512397 0,25483477 ! positive regulation of multicellular organismal process GO:0051240 76 76 0,000 0,2512397 0,25469459 ! cellular metal ion homeostasis GO:0006875 77 77 0,000 0,25410093 0,25745355 ! positive regulation of protein kinase cascade GO:0010740 79 78 0,000 0,25695163 0,26019883 ! metal ion homeostasis GO:0055065 78 78 0,000 0,25695163 0,26005594 ! regulation of immune response GO:0050776 78 78 0,000 0,25695163 0,25991321 ! glycoprotein biosynthetic process GO:0009101 80 80 0,000 0,26262166 0,26550286 ! ribonucleotide metabolic process GO:0009259 83 83 0,000 0,27104876 0,27387218 ! ncRNA processing GO:0034470 83 83 0,000 0,27104876 0,27372211 ! cellular amino acid derivative metabolic process GO:0006575 87 84 0,000 0,27383715 0,27638657 ! nitrogen compound biosynthetic process GO:0044271 86 85 0,000 0,27661529 0,27903776 ! organophosphate metabolic process GO:0019637 87 86 0,000 0,27938321 0,28167574 GO:0006644|phospholipid metabolic process, ! male gamete generation GO:0048232 90 88 0,000 0,28488853 0,28706919 GO:0007283|spermatogenesis, ! purine nucleotide biosynthetic process GO:0006164 88 88 0,000 0,28488853 0,28691233 ! chemotaxis GO:0006935 90 89 0,000 0,287626 0,28951104 GO:0042330|taxis, ! cellular di-, tri-valent inorganic cation homeostasis GO:0030005 89 89 0,000 0,287626 0,28935301 ! regulation of Ras protein signal transduction GO:0046578 90 90 0,000 0,29035339 0,29193742 ! di-, tri-valent inorganic cation homeostasis GO:0055066 91 91 0,000 0,29307074 0,29450893 ! DNA replication GO:0006260 91 91 0,000 0,29307074 0,29434843 ! visual perception GO:0007601 93 92 0,000 0,29577809 0,29690578 GO:0050953|sensory perception of light stimulus, ! regulation of response to stress GO:0080134 97 94 0,000 0,3011629 0,30214655 ! cofactor metabolic process GO:0051186 95 94 0,000 0,3011629 0,30198216 ! endocytosis GO:0006897 99 98 0,000 0,31181399 0,31249221 GO:0010324|membrane invagination, ! glycoprotein metabolic process GO:0009100 99 98 0,000 0,31181399 0,31232238 ! regulation of system process GO:0044057 98 98 0,000 0,31181399 0,31215273 ! anti-apoptosis GO:0006916 100 99 0,000 0,31445227 0,31462298 ! response to other organism GO:0051707 101 100 0,000 0,31708083 0,31708083