pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6679-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of protein export from nucleus GO:0046825 10 7 2,000 1,401E-06 3,423E-03 ! ER overload response GO:0006983 13 8 2,000 2,236E-06 2,731E-03 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 2,000 2,236E-06 1,821E-03 ! protein amino acid autophosphorylation GO:0046777 157 64 4,000 2,961E-06 1,808E-03 ! mammary gland development GO:0030879 93 40 3,000 1,133E-05 5,536E-03 ! cellular response to hormone stimulus GO:0032870 182 85 4,000 1,202E-05 4,894E-03 ! regulation of intracellular protein transport GO:0033157 86 42 3,000 1,38E-05 4,817E-03 ! regulation of epithelial cell proliferation GO:0050678 122 45 3,000 1,823E-05 5,566E-03 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 3,000 1,991E-05 5,405E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 2,000 3,177E-05 7,761E-03 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 2,000 4,416E-05 9,807E-03 ! regulation of intracellular transport GO:0032386 108 57 3,000 4,68E-05 9,528E-03 ! positive regulation of cell migration GO:0030335 137 58 3,000 5,013E-05 9,421E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 2,000 5,139E-05 8,967E-03 ! positive regulation of intracellular transport GO:0032388 42 22 2,000 5,935E-05 9,666E-03 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 2,000 7,761E-05 0,01184983 ! positive regulation of cell motion GO:0051272 157 65 3,000 7,852E-05 0,01128398 ! protein import into nucleus, translocation GO:0000060 51 25 2,000 8,797E-05 0,01193931 ! protein tetramerization GO:0051262 57 25 2,000 8,797E-05 0,01131092 ! response to endoplasmic reticulum stress GO:0034976 46 26 2,000 9,919E-05 0,01211629 ! lung development GO:0030324 165 69 3,000 9,92E-05 0,01154011 ! insulin receptor signaling pathway GO:0008286 66 27 2,000 1,113E-04 0,01236038 ! respiratory tube development GO:0030323 171 72 3,000 1,171E-04 0,0124391 ! negative regulation of bone resorption GO:0045779 10 5 1,000 1,18E-04 0,01200873 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 1,000 1,18E-04 0,01152838 ! positive regulation of glycolysis GO:0045821 13 5 1,000 1,18E-04 0,01108498 ! regulation of phospholipase A2 activity GO:0032429 15 5 1,000 1,18E-04 0,01067443 ! glial cell migration GO:0008347 10 5 1,000 1,18E-04 0,0102932 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 1,000 1,18E-04 9,938E-03 ! protein insertion into membrane GO:0051205 17 5 1,000 1,18E-04 9,607E-03 ! respiratory system development GO:0060541 175 74 3,000 1,303E-04 0,01026709 ! ER-nuclear signaling pathway GO:0006984 52 29 2,000 1,384E-04 0,01056217 ! forebrain regionalization GO:0021871 9 6 1,000 1,766E-04 0,01307073 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 1,000 1,766E-04 0,01268629 ! protein lipoylation GO:0009249 10 6 1,000 1,766E-04 0,01232383 ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 1,000 1,766E-04 0,0119815 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! negative regulation of multicellular organism growth GO:0040015 9 6 1,000 1,766E-04 0,01165767 ! negative regulation of neuroblast proliferation GO:0007406 25 6 1,000 1,766E-04 0,01135089 ! ectodermal gut morphogenesis GO:0048567 16 6 1,000 1,766E-04 0,01105984 GO:0007439|ectodermal gut development, ! response to hypoxia GO:0001666 178 81 3,000 1,849E-04 0,01129277 ! positive regulation of catabolic process GO:0009896 72 32 2,000 1,864E-04 0,0111056 ! response to oxygen levels GO:0070482 183 83 3,000 2,031E-04 0,01181594 ! regulation of protein transport GO:0051223 165 87 3,000 2,435E-04 0,01383161 GO:0070201|regulation of establishment of protein localization, ! regulation of helicase activity GO:0051095 16 7 1,000 2,466E-04 0,01369315 ! mRNA stabilization GO:0048255 18 7 1,000 2,466E-04 0,01338885 GO:0043489|RNA stabilization, ! protein-cofactor linkage GO:0018065 13 7 1,000 2,466E-04 0,01309779 ! spinal cord patterning GO:0021511 14 7 1,000 2,466E-04 0,01281912 ! male sex determination GO:0030238 15 7 1,000 2,466E-04 0,01255205 ! G1 DNA damage checkpoint GO:0031571 20 7 1,000 2,466E-04 0,01229589 ! B cell lineage commitment GO:0002326 21 7 1,000 2,466E-04 0,01204997 ! negative regulation of focal adhesion formation GO:0051895 21 7 1,000 2,466E-04 0,01181369 ! cranial nerve morphogenesis GO:0021602 12 7 1,000 2,466E-04 0,01158651 ! T cell lineage commitment GO:0002360 16 7 1,000 2,466E-04 0,01136789 ! anaphase GO:0051322 18 7 1,000 2,466E-04 0,01115738 GO:0000090|mitotic anaphase, ! tube morphogenesis GO:0035239 194 89 3,000 2,656E-04 0,01179889 ! tissue remodeling GO:0048771 78 37 2,000 2,883E-04 0,01257757 ! ossification GO:0001503 205 91 3,000 2,892E-04 0,01239606 ! gland development GO:0048732 220 91 3,000 2,892E-04 0,01218233 ! bone development GO:0060348 206 92 3,000 3,016E-04 0,01248694 ! cellular response to insulin stimulus GO:0032869 85 38 2,000 3,122E-04 0,01271316 ! positive regulation of MAP kinase activity GO:0043406 174 93 3,000 3,143E-04 0,01258681 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 1,000 3,281E-04 0,01292759 ! T-helper 1 type immune response GO:0042088 12 8 1,000 3,281E-04 0,01272239 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 3,281E-04 0,0125236 ! positive regulation of endothelial cell migration GO:0010595 19 8 1,000 3,281E-04 0,01233093 ! regulation of vascular permeability GO:0043114 12 8 1,000 3,281E-04 0,0121441 ! regulation of T cell differentiation in the thymus GO:0033081 14 8 1,000 3,281E-04 0,01196284 ! regulation of focal adhesion formation GO:0051893 23 8 1,000 3,281E-04 0,01178692 ! response to tumor cell GO:0002347 16 8 1,000 3,281E-04 0,01161609 ! regulation of respiratory burst GO:0060263 12 8 1,000 3,281E-04 0,01145015 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 1,000 3,281E-04 0,01128888 ! regulation of protein localization GO:0032880 188 97 3,000 3,69E-04 0,0125208 ! dorsal/ventral pattern formation GO:0009953 75 42 2,000 4,206E-04 0,01407689 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 4,209E-04 0,0138943 ! Golgi to endosome transport GO:0006895 25 9 1,000 4,209E-04 0,01370904 ! induction of positive chemotaxis GO:0050930 17 9 1,000 4,209E-04 0,01352866 ! regulation of glycolysis GO:0006110 20 9 1,000 4,209E-04 0,01335296 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 1,000 4,209E-04 0,01318177 ! hormone-mediated signaling GO:0009755 84 43 2,000 4,51E-04 0,01394813 ! branching morphogenesis of a tube GO:0048754 102 45 2,000 5,16E-04 0,01575783 ! regulation of developmental growth GO:0048638 16 10 1,000 5,249E-04 0,015831 ! smoothened signaling pathway GO:0007224 18 10 1,000 5,249E-04 0,01563794 ! lung alveolus development GO:0048286 26 10 1,000 5,249E-04 0,01544953 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 1,000 5,249E-04 0,01526561 ! motor axon guidance GO:0008045 22 10 1,000 5,249E-04 0,01508601 ! regulation of bone resorption GO:0045124 25 10 1,000 5,249E-04 0,01491059 ! protein heterooligomerization GO:0051291 17 10 1,000 5,249E-04 0,01473921 ! spinal cord motor neuron differentiation GO:0021522 19 10 1,000 5,249E-04 0,01457172 ! midbrain development GO:0030901 14 10 1,000 5,249E-04 0,01440799 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 1,000 5,249E-04 0,0142479 GO:0043470|regulation of carbohydrate catabolic process, ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 1,000 5,249E-04 0,01409133 ! regulation of gene-specific transcription GO:0032583 102 46 2,000 5,506E-04 0,01462155 ! positive regulation of protein transport GO:0051222 80 46 2,000 5,506E-04 0,01446433 ! neural tube development GO:0021915 91 47 2,000 5,867E-04 0,01524771 ! response to insulin stimulus GO:0032868 98 47 2,000 5,867E-04 0,01508721 ! neuron fate specification GO:0048665 18 11 1,000 6,401E-04 0,01628875 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 1,000 6,401E-04 0,01612082 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 1,000 6,401E-04 0,01595632 ! keratinocyte proliferation GO:0043616 19 11 1,000 6,401E-04 0,01579515 ! blood vessel remodeling GO:0001974 30 11 1,000 6,401E-04 0,0156372 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 1,000 6,401E-04 0,01548237 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 23 11 1,000 6,401E-04 0,01533058 ! peptide or protein amino-terminal blocking GO:0018409 22 11 1,000 6,401E-04 0,01518174 ! regulation of intracellular pH GO:0051453 21 11 1,000 6,401E-04 0,01503577 ! regulation of smoothened signaling pathway GO:0008589 27 11 1,000 6,401E-04 0,01489257 ! positive regulation of leukocyte migration GO:0002687 28 11 1,000 6,401E-04 0,01475207 ! embryonic gut development GO:0048566 19 11 1,000 6,401E-04 0,0146142 ! regulation of embryonic development GO:0045995 35 11 1,000 6,401E-04 0,01447889 ! positive regulation of cellular catabolic process GO:0031331 34 12 1,000 7,664E-04 0,01717628 ! virus-host interaction GO:0019048 30 12 1,000 7,664E-04 0,01702013 ! regulation of positive chemotaxis GO:0050926 22 12 1,000 7,664E-04 0,0168668 GO:0050927|positive regulation of positive chemotaxis, ! ventral spinal cord development GO:0021517 25 12 1,000 7,664E-04 0,0167162 ! cranial nerve development GO:0021545 23 12 1,000 7,664E-04 0,01656827 ! zymogen activation GO:0031638 18 12 1,000 7,664E-04 0,01642294 ! regulation of leukocyte migration GO:0002685 29 12 1,000 7,664E-04 0,01628013 ! negative regulation of mast cell proliferation GO:0070667 24 12 1,000 7,664E-04 0,01613978 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 1,000 7,664E-04 0,01600184 ! localization within membrane GO:0051668 26 12 1,000 7,664E-04 0,01586623 ! morphogenesis of a branching structure GO:0001763 116 52 2,000 7,896E-04 0,01621037 ! epithelial tube morphogenesis GO:0060562 114 54 2,000 8,818E-04 0,01795156 ! response to X-ray GO:0010165 28 13 1,000 9,036E-04 0,0182447 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 1,000 9,036E-04 0,01809516 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of monooxygenase activity GO:0032768 35 13 1,000 9,036E-04 0,01794804 ! regulation of mRNA stability GO:0043488 32 13 1,000 9,036E-04 0,0178033 ! digestive tract morphogenesis GO:0048546 31 13 1,000 9,036E-04 0,01766087 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! response to UV GO:0009411 120 55 2,000 9,303E-04 0,01803763 ! regulation of DNA replication GO:0006275 105 56 2,000 9,805E-04 0,01886105 ! regulation of bone remodeling GO:0046850 143 57 2,000 1,032E-03 0,01970372 ! hair follicle morphogenesis GO:0031069 27 14 1,000 1,052E-03 0,01992027 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 1,000 1,052E-03 0,01976704 GO:0060675|ureteric bud morphogenesis, ! regulation of cellular pH GO:0030641 27 14 1,000 1,052E-03 0,01961615 ! response to gamma radiation GO:0010332 30 14 1,000 1,052E-03 0,01946754 ! regulation of RNA stability GO:0043487 33 14 1,000 1,052E-03 0,01932117 ! release of cytochrome c from mitochondria GO:0001836 31 14 1,000 1,052E-03 0,01917698 ! regulation of tissue remodeling GO:0034103 146 58 2,000 1,086E-03 0,01965158 ! lipid modification GO:0030258 112 60 2,000 1,198E-03 0,02152528 ! N-terminal protein amino acid modification GO:0031365 30 15 1,000 1,211E-03 0,02159378 ! negative regulation of bone remodeling GO:0046851 34 15 1,000 1,211E-03 0,0214373 ! regulation of mRNA processing GO:0050684 26 15 1,000 1,211E-03 0,02128308 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 1,000 1,211E-03 0,02113106 ! regulation of exocytosis GO:0017157 26 15 1,000 1,211E-03 0,02098119 ! G1/S transition checkpoint GO:0031575 37 15 1,000 1,211E-03 0,02083344 ! mesoderm development GO:0007498 128 63 2,000 1,38E-03 0,02357805 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 1,381E-03 0,02342585 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 1,000 1,381E-03 0,02326429 ! positive regulation of protein import into nucleus GO:0042307 34 16 1,000 1,381E-03 0,02310494 ! negative regulation of tissue remodeling GO:0034104 37 16 1,000 1,381E-03 0,02294777 ! negative regulation of leukocyte proliferation GO:0070664 32 16 1,000 1,381E-03 0,02279271 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 1,381E-03 0,02263974 ! response to peptide hormone stimulus GO:0043434 129 64 2,000 1,444E-03 0,02352402 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 1,000 1,561E-03 0,02526128 ! negative regulation of homeostatic process GO:0032845 36 17 1,000 1,561E-03 0,02509509 ! embryonic limb morphogenesis GO:0030326 139 67 2,000 1,648E-03 0,02631835 GO:0035113|embryonic appendage morphogenesis, ! epidermis morphogenesis GO:0048730 43 18 1,000 1,753E-03 0,02780233 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 1,000 1,753E-03 0,02762296 ! nerve development GO:0021675 34 18 1,000 1,753E-03 0,02744589 ! cell differentiation in spinal cord GO:0021515 37 19 1,000 1,954E-03 0,03041055 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 1,000 1,954E-03 0,03021808 ! neuromuscular junction development GO:0007528 43 19 1,000 1,954E-03 0,03002803 ! regulation of endothelial cell migration GO:0010594 45 19 1,000 1,954E-03 0,02984036 ! proximal/distal pattern formation GO:0009954 33 19 1,000 1,954E-03 0,02965501 ! embryonic organ morphogenesis GO:0048562 34 19 1,000 1,954E-03 0,02947196 ! appendage morphogenesis GO:0035107 150 72 2,000 2,026E-03 0,03037164 GO:0035108|limb morphogenesis, ! regulation of MAPKKK cascade GO:0043408 157 72 2,000 2,026E-03 0,03018644 ! appendage development GO:0048736 151 73 2,000 2,108E-03 0,03121095 GO:0060173|limb development, ! phosphoinositide phosphorylation GO:0046854 40 20 1,000 2,167E-03 0,03188534 ! regulation of carbohydrate metabolic process GO:0006109 37 20 1,000 2,167E-03 0,03169441 GO:0010675|regulation of cellular carbohydrate metabolic process, ! apoptotic mitochondrial changes GO:0008637 42 20 1,000 2,167E-03 0,03150575 ! peptidyl-serine phosphorylation GO:0018105 44 20 1,000 2,167E-03 0,03131933 ! fatty acid beta-oxidation GO:0006635 36 20 1,000 2,167E-03 0,0311351 ! negative regulation of T cell activation GO:0050868 41 20 1,000 2,167E-03 0,03095302 ! lipid phosphorylation GO:0046834 43 21 1,000 2,389E-03 0,0339355 ! ovarian follicle development GO:0001541 39 21 1,000 2,389E-03 0,03373934 ! negative regulation of intracellular transport GO:0032387 44 21 1,000 2,389E-03 0,03354544 ! positive regulation of osteoblast differentiation GO:0045669 52 21 1,000 2,389E-03 0,03335375 ! collagen catabolic process GO:0030574 29 21 1,000 2,389E-03 0,03316424 ! camera-type eye morphogenesis GO:0048593 47 21 1,000 2,389E-03 0,03297687 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 1,000 2,389E-03 0,03279161 ! regulation of catabolic process GO:0009894 173 77 2,000 2,454E-03 0,03349907 ! positive regulation of protein catabolic process GO:0045732 44 22 1,000 2,622E-03 0,03558943 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 1,000 2,622E-03 0,03539281 ! cellular response to starvation GO:0009267 37 22 1,000 2,622E-03 0,03519834 ! ureteric bud development GO:0001657 50 22 1,000 2,622E-03 0,035006 ! cell aging GO:0007569 48 22 1,000 2,622E-03 0,03481575 ! positive regulation of locomotion GO:0040017 44 22 1,000 2,622E-03 0,03462756 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! peptidyl-serine modification GO:0018209 50 22 1,000 2,622E-03 0,03444139 ! gut development GO:0048565 44 22 1,000 2,622E-03 0,03425721 ! protein oligomerization GO:0051259 149 79 2,000 2,64E-03 0,03430814 ! positive regulation of DNA replication GO:0045740 44 23 1,000 2,865E-03 0,03703896 ! gluconeogenesis GO:0006094 38 23 1,000 2,865E-03 0,03684401 ! regulation of chemotaxis GO:0050920 45 23 1,000 2,865E-03 0,03665111 ! regulation of cell-matrix adhesion GO:0001952 81 23 1,000 2,865E-03 0,03646022 GO:0010810|regulation of cell-substrate adhesion, ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 1,000 2,865E-03 0,03627131 ! protein import into nucleus GO:0006606 174 82 2,000 2,935E-03 0,03695428 ! nuclear import GO:0051170 177 83 2,000 3,037E-03 0,03804802 ! positive regulation of cell adhesion GO:0045785 61 24 1,000 3,119E-03 0,03887512 ! regulation of cellular catabolic process GO:0031329 55 24 1,000 3,119E-03 0,03867778 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 1,000 3,119E-03 0,03848244 ! sex determination GO:0007530 48 24 1,000 3,119E-03 0,03828906 ! regulation of oxidoreductase activity GO:0051341 48 24 1,000 3,119E-03 0,03809762 ! negative regulation of growth GO:0045926 168 85 2,000 3,248E-03 0,03948157 ! regulation of neuron differentiation GO:0045664 187 85 2,000 3,248E-03 0,03928612 ! vasculogenesis GO:0001570 49 25 1,000 3,382E-03 0,04070642 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 1,000 3,382E-03 0,04050688 ! regulation of behavior GO:0050795 48 25 1,000 3,382E-03 0,04030928 ! negative regulation of DNA replication GO:0008156 45 25 1,000 3,382E-03 0,04011361 ! interaction with host GO:0051701 66 25 1,000 3,382E-03 0,03991982 ! myelination GO:0042552 50 26 1,000 3,656E-03 0,04294147 ! pyruvate metabolic process GO:0006090 43 26 1,000 3,656E-03 0,04273601 ! molting cycle process GO:0022404 52 26 1,000 3,656E-03 0,0425325 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! protein amino acid alkylation GO:0008213 59 26 1,000 3,656E-03 0,04233093 GO:0006479|protein amino acid methylation, ! spinal cord development GO:0021510 54 26 1,000 3,656E-03 0,04213125 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 1,000 3,656E-03 0,04193345 ! osteoblast differentiation GO:0001649 63 26 1,000 3,656E-03 0,0417375 ! negative regulation of cell development GO:0010721 83 26 1,000 3,656E-03 0,04154338 GO:0050768|negative regulation of neurogenesis, ! regulation of osteoblast differentiation GO:0045667 68 26 1,000 3,656E-03 0,04135105 ! regulation of cAMP metabolic process GO:0030814 182 89 2,000 3,698E-03 0,04162915 ! protein localization in nucleus GO:0034504 192 89 2,000 3,698E-03 0,04143819 ! embryonic pattern specification GO:0009880 49 27 1,000 3,94E-03 0,04394803 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 1,000 3,94E-03 0,04374826 ! regulation of endothelial cell proliferation GO:0001936 60 27 1,000 3,94E-03 0,04355031 ! mitochondrial membrane organization GO:0007006 60 27 1,000 3,94E-03 0,04335413 ! multicellular organismal catabolic process GO:0044243 38 27 1,000 3,94E-03 0,04315972 ! response to starvation GO:0042594 47 27 1,000 3,94E-03 0,04296704 ! cellular response to nutrient levels GO:0031669 45 27 1,000 3,94E-03 0,04277608 ! negative regulation of lymphocyte activation GO:0051250 55 27 1,000 3,94E-03 0,0425868 ! regulation of cell adhesion GO:0030155 241 92 2,000 4,058E-03 0,04367686 ! regulation of fibroblast proliferation GO:0048145 56 28 1,000 4,233E-03 0,04535791 ! neuron fate commitment GO:0048663 52 28 1,000 4,233E-03 0,04515984 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 1,000 4,233E-03 0,0449635 ! protein amino acid acylation GO:0043543 59 28 1,000 4,233E-03 0,04476885 ! base-excision repair GO:0006284 41 28 1,000 4,233E-03 0,04457588 ! peptidyl-tyrosine modification GO:0018212 57 28 1,000 4,233E-03 0,04438457 ! lipid oxidation GO:0034440 48 28 1,000 4,233E-03 0,04419489 GO:0019395|fatty acid oxidation, ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 2,000 4,44E-03 0,04615448 ! negative regulation of multicellular organismal process GO:0051241 174 95 2,000 4,44E-03 0,04595891 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 1,000 4,536E-03 0,04676208 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 1,000 4,536E-03 0,0465656 ! regulation of DNA metabolic process GO:0051052 188 97 2,000 4,706E-03 0,04809995 ! regulation of nucleotide metabolic process GO:0006140 197 98 2,000 4,842E-03 0,04928882 ! tissue homeostasis GO:0001894 50 30 1,000 4,85E-03 0,04915963 GO:0048871|multicellular organismal homeostasis, ! ovulation cycle process GO:0022602 55 31 1,000 5,172E-03 0,05221491 ! cellular response to extracellular stimulus GO:0031668 52 31 1,000 5,172E-03 0,05200003 ! ensheathment of neurons GO:0007272 64 31 1,000 5,172E-03 0,05178692 GO:0008366|axon ensheathment, ! negative regulation of leukocyte activation GO:0002695 60 31 1,000 5,172E-03 0,05157554 ! fatty acid catabolic process GO:0009062 54 31 1,000 5,172E-03 0,05136589 ! eye morphogenesis GO:0048592 65 31 1,000 5,172E-03 0,05115793 ! collagen metabolic process GO:0032963 49 32 1,000 5,505E-03 0,05422602 ! metanephros development GO:0001656 81 32 1,000 5,505E-03 0,05400825 ! response to mechanical stimulus GO:0009612 60 32 1,000 5,505E-03 0,05379221 ! regulation of protein import into nucleus GO:0042306 69 32 1,000 5,505E-03 0,0535779 ! mesoderm formation GO:0001707 73 32 1,000 5,505E-03 0,05336529 ! hexose biosynthetic process GO:0019319 53 32 1,000 5,505E-03 0,05315436 ! ovulation cycle GO:0042698 57 32 1,000 5,505E-03 0,05294509 ! peripheral nervous system development GO:0007422 68 32 1,000 5,505E-03 0,05273746 ! BMP signaling pathway GO:0030509 71 32 1,000 5,505E-03 0,05253146 ! hindbrain development GO:0030902 65 32 1,000 5,505E-03 0,05232706 ! regulation of pH GO:0006885 56 33 1,000 5,847E-03 0,05536216 ! positive regulation of gene-specific transcription GO:0043193 70 33 1,000 5,847E-03 0,05514841 ! response to ionizing radiation GO:0010212 74 33 1,000 5,847E-03 0,0549363 ! negative regulation of protein transport GO:0051224 74 33 1,000 5,847E-03 0,05472581 ! formation of primary germ layer GO:0001704 76 34 1,000 6,198E-03 0,05779386 ! cell fate specification GO:0001708 56 34 1,000 6,198E-03 0,05757411 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 1,000 6,198E-03 0,05735603 ! DNA damage checkpoint GO:0000077 78 35 1,000 6,559E-03 0,06046622 ! negative regulation of DNA metabolic process GO:0051053 65 35 1,000 6,559E-03 0,06023891 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 1,000 6,559E-03 0,06001329 ! mesoderm morphogenesis GO:0048332 80 35 1,000 6,559E-03 0,05978936 ! telencephalon development GO:0021537 81 35 1,000 6,559E-03 0,0595671 ! calcium-mediated signaling GO:0019722 67 35 1,000 6,559E-03 0,05934648 ! negative regulation of hydrolase activity GO:0051346 66 36 1,000 6,929E-03 0,06246473 ! embryonic organ development GO:0048568 67 36 1,000 6,929E-03 0,06223508 ! monosaccharide biosynthetic process GO:0046364 57 36 1,000 6,929E-03 0,06200711 ! regulation of smooth muscle cell proliferation GO:0048660 64 37 1,000 7,309E-03 0,06516425 ! negative regulation of cell adhesion GO:0007162 94 37 1,000 7,309E-03 0,06492729 ! odontogenesis GO:0042476 74 37 1,000 7,309E-03 0,06469204 ! female gonad development GO:0008585 71 37 1,000 7,309E-03 0,0644585 ! negative regulation of cell activation GO:0050866 69 37 1,000 7,309E-03 0,06422663 ! positive regulation of DNA metabolic process GO:0051054 77 38 1,000 7,697E-03 0,0673999 ! embryonic skeletal system morphogenesis GO:0048704 68 38 1,000 7,697E-03 0,06715919 ! DNA integrity checkpoint GO:0031570 82 38 1,000 7,697E-03 0,06692018 ! glycogen metabolic process GO:0005977 63 38 1,000 7,697E-03 0,06668288 ! neural tube formation GO:0001841 79 38 1,000 7,697E-03 0,06644725 ! mitotic cell cycle checkpoint GO:0007093 76 39 1,000 8,095E-03 0,06963549 ! carbohydrate homeostasis GO:0033500 59 39 1,000 8,095E-03 0,06939116 GO:0042593|glucose homeostasis, ! glucan metabolic process GO:0044042 64 39 1,000 8,095E-03 0,06914853 GO:0006073|cellular glucan metabolic process, ! development of primary female sexual characteristics GO:0046545 80 40 1,000 8,502E-03 0,07237131 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 73 40 1,000 8,502E-03 0,07212002 ! regulation of action potential in neuron GO:0019228 80 40 1,000 8,502E-03 0,07187047 ! gliogenesis GO:0042063 91 41 1,000 8,918E-03 0,07512643 ! multicellular organismal metabolic process GO:0044236 64 41 1,000 8,918E-03 0,07486826 ! monovalent inorganic cation homeostasis GO:0055067 72 41 1,000 8,918E-03 0,07461187 ! embryonic epithelial tube formation GO:0001838 85 41 1,000 8,918E-03 0,07435722 ! alcohol biosynthetic process GO:0046165 65 42 1,000 9,343E-03 0,07763475 ! T cell differentiation GO:0030217 93 42 1,000 9,343E-03 0,07737158 ! regulation of T cell differentiation GO:0045580 78 42 1,000 9,343E-03 0,07711019 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 1,000 9,777E-03 0,08041839 ! regulation of T cell proliferation GO:0042129 80 43 1,000 9,777E-03 0,08014853 ! energy reserve metabolic process GO:0006112 76 44 1,000 0,01021917 0,08349645 ! positive regulation of response to external stimulus GO:0032103 88 44 1,000 0,01021917 0,08321813 ! double-strand break repair GO:0006302 85 44 1,000 0,01021917 0,08294166 ! induction of apoptosis by intracellular signals GO:0008629 95 45 1,000 0,01067048 0,08631784 ! biopolymer methylation GO:0043414 91 45 1,000 0,01067048 0,08603296 ! B cell differentiation GO:0030183 124 45 1,000 0,01067048 0,08574996 ! developmental growth GO:0048589 88 45 1,000 0,01067048 0,08546881 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 1,000 0,01113048 0,08886193 ! cell growth GO:0016049 90 46 1,000 0,01113048 0,08857248 ! mitochondrial transport GO:0006839 94 48 1,000 0,01207626 0,09578667 ! endosome transport GO:0016197 127 48 1,000 0,01207626 0,09547668 ! vascular process in circulatory system GO:0003018 85 48 1,000 0,01207626 0,09516869 ! methylation GO:0032259 97 48 1,000 0,01207626 0,09486268 ! positive regulation of cell cycle GO:0045787 96 48 1,000 0,01207626 0,09455863 ! regulation of lymphocyte differentiation GO:0045619 92 49 1,000 0,01256192 0,09804715 ! regulation of mast cell proliferation GO:0070666 89 49 1,000 0,01256192 0,0977349 ! regulation of action potential GO:0001508 102 50 1,000 0,013056 0,10125655 ! induction of apoptosis by extracellular signals GO:0008624 99 50 1,000 0,013056 0,10093612 ! activation of caspase activity GO:0006919 95 50 1,000 0,013056 0,10061771 ! regulation of ossification GO:0030278 123 50 1,000 0,013056 0,1003013 ! negative regulation of immune system process GO:0002683 101 51 1,000 0,01355845 0,1038348 ! response to estrogen stimulus GO:0043627 98 52 1,000 0,01406921 0,1074096 ! morphogenesis of embryonic epithelium GO:0016331 106 52 1,000 0,01406921 0,10707499 ! positive regulation of growth GO:0045927 96 53 1,000 0,0145882 0,11068004 ! regulation of leukocyte proliferation GO:0070663 97 53 1,000 0,0145882 0,11033738 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of neuron apoptosis GO:0043523 117 53 1,000 0,0145882 0,10999683 ! synapse organization GO:0050808 102 53 1,000 0,0145882 0,10965838 ! regulation of angiogenesis GO:0045765 125 54 1,000 0,01511537 0,11327254 ! protein amino acid lipidation GO:0006497 109 54 1,000 0,01511537 0,11292614 ! activation of phospholipase C activity GO:0007202 110 54 1,000 0,01511537 0,11258186 GO:0010863|positive regulation of phospholipase C activity, ! embryonic skeletal system development GO:0048706 101 54 1,000 0,01511537 0,11223966 ! regulation of cell shape GO:0008360 142 54 1,000 0,01511537 0,11189954 ! positive regulation of phospholipase activity GO:0010518 111 55 1,000 0,01565066 0,11551224 ! regulation of multicellular organism growth GO:0040014 90 55 1,000 0,01565066 0,11516431 ! skeletal muscle fiber development GO:0048741 130 56 1,000 0,01619399 0,11880459 ! regulation of protein catabolic process GO:0042176 126 56 1,000 0,01619399 0,11844889 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 1,000 0,01674533 0,12211592 ! positive regulation of caspase activity GO:0043280 108 57 1,000 0,01674533 0,12175248 GO:0010952|positive regulation of peptidase activity, ! muscle fiber development GO:0048747 131 57 1,000 0,01674533 0,12139119 ! regulation of phospholipase activity GO:0010517 113 57 1,000 0,01674533 0,12103205 ! heart morphogenesis GO:0003007 105 57 1,000 0,01674533 0,12067502 ! nucleotide-excision repair GO:0006289 91 57 1,000 0,01674533 0,1203201 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 0,01718412 0,12311088 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 0,01718412 0,1227509 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 0,01718412 0,12239303 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,01718412 0,12203724 ! positive regulation of helicase activity GO:0051096 12 5 0,000 0,01718412 0,12168351 ! neuron fate determination GO:0048664 7 5 0,000 0,01718412 0,12133182 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01718412 0,12098216 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 0,01718412 0,12063451 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 0,01718412 0,12028885 ! polyol transport GO:0015791 12 5 0,000 0,01718412 0,11994517 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,01718412 0,11960345 ! response to superoxide GO:0000303 10 5 0,000 0,01718412 0,11926366 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 0,01718412 0,11892581 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 0,01718412 0,11858986 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,01718412 0,1182558 ! female meiosis GO:0007143 10 5 0,000 0,01718412 0,11792362 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 0,01718412 0,1175933 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,01718412 0,11726483 ! hypothalamus development GO:0021854 9 5 0,000 0,01718412 0,11693819 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 0,01718412 0,11661336 ! cobalt ion transport GO:0006824 11 5 0,000 0,01718412 0,11629033 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 0,01718412 0,11596909 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 0,01718412 0,11564961 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,01718412 0,11533189 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,01718412 0,11501592 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 0,01718412 0,11470166 ! embryonic camera-type eye development GO:0031076 12 5 0,000 0,01718412 0,11438913 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,01718412 0,11407829 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01718412 0,11376913 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 0,01718412 0,11346165 ! transposition GO:0032196 9 5 0,000 0,01718412 0,11315582 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 0,01718412 0,11285164 ! negative chemotaxis GO:0050919 16 5 0,000 0,01718412 0,11254909 ! positive regulation of histone modification GO:0031058 6 5 0,000 0,01718412 0,11224815 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,01718412 0,11194882 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 0,01718412 0,11165109 ! behavioral response to pain GO:0048266 10 5 0,000 0,01718412 0,11135493 ! clathrin coat assembly GO:0048268 15 5 0,000 0,01718412 0,11106034 ! Notch receptor processing GO:0007220 11 5 0,000 0,01718412 0,11076731 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01718412 0,11047581 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 0,01718412 0,11018585 ! micturition GO:0060073 9 5 0,000 0,01718412 0,10989741 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,01718412 0,10961047 ! copulation GO:0007620 9 5 0,000 0,01718412 0,10932502 ! glial cell fate commitment GO:0021781 14 5 0,000 0,01718412 0,10904106 ! protein maturation by protein folding GO:0022417 14 5 0,000 0,01718412 0,10875857 ! bioluminescence GO:0008218 9 5 0,000 0,01718412 0,10847754 ! spermidine metabolic process GO:0008216 7 5 0,000 0,01718412 0,10819796 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,01718412 0,10791982 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,01718412 0,1076431 ! apoptotic cell clearance GO:0043277 23 5 0,000 0,01718412 0,1073678 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,01718412 0,1070939 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 0,01718412 0,1068214 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,01718412 0,10655028 ! grooming behavior GO:0007625 6 5 0,000 0,01718412 0,10628053 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 0,01718412 0,10601214 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,01718412 0,10574511 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 0,01718412 0,10547942 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01718412 0,10521506 ! response to protozoan GO:0001562 13 5 0,000 0,01718412 0,10495202 ! lymph vessel development GO:0001945 10 5 0,000 0,01718412 0,1046903 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 0,01718412 0,10442987 ! endochondral ossification GO:0001958 17 5 0,000 0,01718412 0,10417074 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,01718412 0,10391289 ! single strand break repair GO:0000012 8 5 0,000 0,01718412 0,10365632 ! parathyroid gland development GO:0060017 14 5 0,000 0,01718412 0,10340101 ! anagen GO:0042640 7 5 0,000 0,01718412 0,10314695 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,01718412 0,10289414 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,01718412 0,10264257 ! cytokine secretion GO:0050663 15 5 0,000 0,01718412 0,10239222 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 0,01718412 0,10214309 ! ceramide catabolic process GO:0046514 7 5 0,000 0,01718412 0,10189517 ! skeletal myofibril assembly GO:0014866 12 5 0,000 0,01718412 0,10164845 ! smooth muscle tissue development GO:0048745 32 5 0,000 0,01718412 0,10140292 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,01718412 0,10115858 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,01718412 0,10091541 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,01718412 0,1006734 ! cardiac muscle fiber development GO:0048739 12 5 0,000 0,01718412 0,10043256 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,01718412 0,10019286 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 9 5 0,000 0,01718412 0,09995431 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,01718412 0,09971689 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 0,01718412 0,09948059 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,01718412 0,09924541 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 0,01718412 0,09901134 ! glycine biosynthetic process GO:0006545 7 5 0,000 0,01718412 0,09877837 ! microvillus organization GO:0032528 8 5 0,000 0,01718412 0,0985465 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 12 5 0,000 0,01718412 0,09831571 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 0,01718412 0,098086 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 0,01718412 0,09785736 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 0,01718412 0,09762979 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 0,01718412 0,09740327 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 0,01718412 0,0971778 ! polyol catabolic process GO:0046174 9 5 0,000 0,01718412 0,09695337 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 0,01718412 0,09672998 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 0,01718412 0,09650761 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 0,01718412 0,09628626 ! muscle cell migration GO:0014812 8 5 0,000 0,01718412 0,09606593 ! mitochondrial fission GO:0000266 8 5 0,000 0,01718412 0,0958466 ! sister chromatid cohesion GO:0007062 15 5 0,000 0,01718412 0,09562827 ! response to tumor necrosis factor GO:0034612 10 5 0,000 0,01718412 0,09541093 ! mRNA transcription GO:0009299 10 5 0,000 0,01718412 0,09519458 ! nerve growth factor processing GO:0032455 9 5 0,000 0,01718412 0,09497921 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 0,01718412 0,09476481 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 0,01718412 0,09455137 ! anaerobic glycolysis GO:0019642 6 5 0,000 0,01718412 0,0943389 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,01718412 0,09412737 ! monocyte activation GO:0042117 10 5 0,000 0,01718412 0,0939168 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,01718412 0,09370716 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,01718412 0,09349846 ! response to food GO:0032094 6 5 0,000 0,01718412 0,09329069 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,01718412 0,09308383 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,01718412 0,0928779 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 0,01718412 0,09267287 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01718412 0,09246874 ! forebrain neuron development GO:0021884 13 5 0,000 0,01718412 0,09226551 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,01718412 0,09206318 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 0,01718412 0,09186173 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 0,01718412 0,09166116 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,01718412 0,09146146 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01718412 0,09126263 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 0,01718412 0,09106466 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,01718412 0,09086755 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 0,01718412 0,09067129 ! lipid glycosylation GO:0030259 7 5 0,000 0,01718412 0,09047588 ! nucleobase transport GO:0015851 6 5 0,000 0,01718412 0,09028131 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01718412 0,09008757 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 0,01718412 0,08989467 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 0,01718412 0,08970258 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 0,01718412 0,08951132 ! basic amino acid transport GO:0015802 12 5 0,000 0,01718412 0,08932087 ! cellular glucose homeostasis GO:0001678 6 5 0,000 0,01718412 0,08913123 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 0,01718412 0,08894239 ! actin nucleation GO:0045010 11 5 0,000 0,01718412 0,08875435 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01718412 0,08856711 ! depurination GO:0045007 5 5 0,000 0,01718412 0,08838065 ! depyrimidination GO:0045008 10 5 0,000 0,01718412 0,08819498 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,01718412 0,08801008 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01718412 0,08782596 ! G2/M transition checkpoint GO:0031576 8 5 0,000 0,01718412 0,08764261 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,01718412 0,08746002 ! zinc ion homeostasis GO:0055069 9 5 0,000 0,01718412 0,08727819 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 10 5 0,000 0,01718412 0,08709711 ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 0,01718412 0,08691679 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01718412 0,08673721 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,01718412 0,08655837 ! activated T cell proliferation GO:0050798 16 5 0,000 0,01718412 0,08638027 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,01718412 0,08620289 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 0,01718412 0,08602625 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,01718412 0,08585033 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01718412 0,08567512 ! gamma-delta T cell activation GO:0046629 6 5 0,000 0,01718412 0,08550063 ! response to arsenic GO:0046685 11 5 0,000 0,01718412 0,08532685 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 0,01718412 0,08515377 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,01718412 0,0849814 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 0,01718412 0,08480972 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 0,01718412 0,08463873 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 0,01718412 0,08446843 ! response to mercury ion GO:0046689 8 5 0,000 0,01718412 0,08429881 ! response to cadmium ion GO:0046686 7 5 0,000 0,01718412 0,08412988 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 0,01718412 0,08396162 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 0,01718412 0,08379403 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 0,01718412 0,08362711 ! bile acid biosynthetic process GO:0006699 7 5 0,000 0,01718412 0,08346085 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 0,01718412 0,08329526 ! ganglioside catabolic process GO:0006689 12 5 0,000 0,01718412 0,08313032 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,01718412 0,08296603 ! decidualization GO:0046697 11 5 0,000 0,01718412 0,08280239 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 0,01718412 0,08263939 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 0,01718412 0,08247703 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 0,01718412 0,08231531 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 0,01718412 0,08215423 ! embryonic cleavage GO:0040016 6 5 0,000 0,01718412 0,08199377 ! peroxisome fission GO:0016559 5 5 0,000 0,01718412 0,08183394 ! histone demethylation GO:0016577 13 5 0,000 0,01718412 0,08167473 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 0,01718412 0,08151613 ! mitotic recombination GO:0006312 9 5 0,000 0,01718412 0,08135816 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 0,01718412 0,08120079 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,01718412 0,08104403 ! metaphase plate congression GO:0051310 7 5 0,000 0,01718412 0,08088788 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01718412 0,08073233 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,01718412 0,08057737 ! enteric nervous system development GO:0048484 8 5 0,000 0,01718412 0,08042301 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 0,01718412 0,08026923 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 0,01718412 0,08011605 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 0,01718412 0,07996345 ! muscle cell proliferation GO:0033002 12 5 0,000 0,01718412 0,07981142 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,01718412 0,07965998 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 0,01718412 0,07950911 ! B cell homeostasis GO:0001782 13 5 0,000 0,01718412 0,07935881 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 0,01718412 0,07920907 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,01718412 0,0790599 ! metaphase GO:0051323 11 5 0,000 0,01718412 0,0789113 ! melatonin biosynthetic process GO:0030187 7 5 0,000 0,01718412 0,07876324 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 0,01718412 0,07861575 ! cellular response to nutrient GO:0031670 8 5 0,000 0,01718412 0,0784688 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,01718412 0,07832241 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 0,01718412 0,07817655 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 0,01718412 0,07803124 ! regulation of hair follicle development GO:0051797 10 5 0,000 0,01718412 0,07788647 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 0,01718412 0,07774224 ! response to redox state GO:0051775 6 5 0,000 0,01718412 0,07759854 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 0,01718412 0,07745537 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 0,01718412 0,07731272 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,01718412 0,07717061 ! brown fat cell differentiation GO:0050873 7 5 0,000 0,01718412 0,07702901 ! regulation of telomerase activity GO:0051972 7 5 0,000 0,01718412 0,07688793 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01718412 0,07674737 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 0,01718412 0,07660732 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01718412 0,07646778 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 0,01718412 0,07632874 ! striatum development GO:0021756 14 5 0,000 0,01718412 0,07619022 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 0,01718412 0,07605219 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,01718412 0,07591466 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,01718412 0,07577763 ! neural plate morphogenesis GO:0001839 7 5 0,000 0,01718412 0,0756411 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 0,01718412 0,07550505 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,01718412 0,0753695 ! T cell activation during immune response GO:0002286 9 5 0,000 0,01718412 0,07523443 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,01718412 0,07509984 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,01718412 0,07496573 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 0,01718412 0,0748321 ! neuroprotection GO:0043526 8 5 0,000 0,01718412 0,07469895 ! regulation of sensory perception GO:0051931 8 5 0,000 0,01718412 0,07456627 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,01718412 0,07443406 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,01718412 0,07430232 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 0,01718412 0,07417104 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 0,01718412 0,07404023 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,01718412 0,07390988 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 0,01718412 0,07377998 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,01718412 0,07365054 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 0,01718412 0,07352156 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 0,01718412 0,07339302 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,01718412 0,07326494 ! spindle assembly GO:0051225 6 5 0,000 0,01718412 0,0731373 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,01718412 0,0730101 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,01718412 0,07288335 ! protein palmitoylation GO:0018345 12 5 0,000 0,01718412 0,07275704 ! drug metabolic process GO:0017144 7 5 0,000 0,01718412 0,07263116 ! stem cell division GO:0017145 11 5 0,000 0,01718412 0,07250572 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,01718412 0,07238071 ! organ regeneration GO:0031100 7 5 0,000 0,01718412 0,07225613 ! carnitine metabolic process GO:0009437 8 5 0,000 0,01718412 0,07213197 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,01718412 0,07200825 ! cellular polysaccharide metabolic process GO:0044264 93 58 1,000 0,01730459 0,07238889 ! lipoprotein biosynthetic process GO:0042158 115 58 1,000 0,01730459 0,07226515 ! aging GO:0007568 112 58 1,000 0,01730459 0,07214183 ! gastrulation GO:0007369 122 58 1,000 0,01730459 0,07201893 ! positive regulation of lipase activity GO:0060193 115 58 1,000 0,01730459 0,07189645 ! kidney development GO:0001822 133 60 1,000 0,01844667 0,0765114 ! camera-type eye development GO:0043010 126 61 1,000 0,01902937 0,07879448 ! viral reproductive process GO:0022415 132 62 1,000 0,01961976 0,08110163 ! DNA damage response, signal transduction GO:0042770 136 62 1,000 0,01961976 0,08096463 ! regulation of homeostatic process GO:0032844 148 62 1,000 0,01961976 0,0808281 ! skeletal system morphogenesis GO:0048705 118 63 1,000 0,02021778 0,08315156 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,02058563 0,08452219 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,02058563 0,08438038 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 0,02058563 0,08423904 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 0,02058563 0,08409817 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,02058563 0,08395777 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 0,02058563 0,08381784 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 0,02058563 0,08367838 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,02058563 0,08353938 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 0,02058563 0,08340084 ! response to oxygen radical GO:0000305 11 6 0,000 0,02058563 0,08326276 ! positive regulation of axon extension GO:0045773 13 6 0,000 0,02058563 0,08312513 ! myoblast cell fate commitment GO:0048625 18 6 0,000 0,02058563 0,08298796 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 0,02058563 0,08285124 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 0,02058563 0,08271497 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,02058563 0,08257915 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,02058563 0,08244378 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 0,02058563 0,08230885 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,02058563 0,08217435 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,02058563 0,0820403 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 0,02058563 0,08190668 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,02058563 0,0817735 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 0,02058563 0,08164075 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 0,02058563 0,08150843 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,02058563 0,08137654 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 0,02058563 0,08124508 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 0,02058563 0,08111404 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,02058563 0,08098342 ! malate metabolic process GO:0006108 13 6 0,000 0,02058563 0,08085322 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 0,02058563 0,08072344 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 0,02058563 0,08059408 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 0,02058563 0,08046513 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 0,02058563 0,08033659 ! protein refolding GO:0042026 15 6 0,000 0,02058563 0,08020846 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,02058563 0,08008074 ! opsonization GO:0008228 8 6 0,000 0,02058563 0,07995342 ! mating behavior GO:0007617 7 6 0,000 0,02058563 0,07982651 ! erythrocyte maturation GO:0043249 8 6 0,000 0,02058563 0,07970001 ! embryonic hemopoiesis GO:0035162 16 6 0,000 0,02058563 0,0795739 ! protein amino acid dealkylation GO:0008214 15 6 0,000 0,02058563 0,07944819 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 0,02058563 0,07932288 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 0,02058563 0,07919796 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,02058563 0,07907343 ! response to interferon-gamma GO:0034341 16 6 0,000 0,02058563 0,0789493 ! toxin metabolic process GO:0009404 11 6 0,000 0,02058563 0,07882556 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,02058563 0,0787022 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 0,02058563 0,07857923 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 0,02058563 0,07845664 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 13 6 0,000 0,02058563 0,07833443 ! cGMP-mediated signaling GO:0019934 14 6 0,000 0,02058563 0,0782126 ! dorsal spinal cord development GO:0021516 10 6 0,000 0,02058563 0,07809116 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,02058563 0,07797008 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 0,02058563 0,07784939 ! thymic T cell selection GO:0045061 16 6 0,000 0,02058563 0,07772906 ! sphingoid catabolic process GO:0046521 8 6 0,000 0,02058563 0,07760911 ! transepithelial chloride transport GO:0030321 12 6 0,000 0,02058563 0,07748953 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 0,02058563 0,07737031 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,02058563 0,07725147 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 0,02058563 0,07713298 ! glutamate catabolic process GO:0006538 12 6 0,000 0,02058563 0,07701486 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 0,02058563 0,0768971 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 0,02058563 0,0767797 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,02058563 0,07666266 ! hyperosmotic response GO:0006972 10 6 0,000 0,02058563 0,07654597 ! L-serine biosynthetic process GO:0006564 7 6 0,000 0,02058563 0,07642964 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 0,02058563 0,07631366 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 0,02058563 0,07619804 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,02058563 0,07608276 ! urea metabolic process GO:0019627 7 6 0,000 0,02058563 0,07596783 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,02058563 0,07585325 ! neutrophil activation GO:0042119 7 6 0,000 0,02058563 0,07573901 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,02058563 0,07562512 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 0,02058563 0,07551157 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,02058563 0,07539836 ! paraxial mesoderm development GO:0048339 16 6 0,000 0,02058563 0,07528549 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 0,02058563 0,07517295 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,02058563 0,07506075 ! neuron apoptosis GO:0051402 15 6 0,000 0,02058563 0,07494889 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,02058563 0,07483736 ! T cell mediated immunity GO:0002456 17 6 0,000 0,02058563 0,07472616 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,02058563 0,07461529 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 0,02058563 0,07450475 ! carnitine transport GO:0015879 10 6 0,000 0,02058563 0,07439453 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,02058563 0,07428464 ! positive regulation of exocytosis GO:0045921 11 6 0,000 0,02058563 0,07417508 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 0,02058563 0,07406584 ! early endosome to late endosome transport GO:0045022 16 6 0,000 0,02058563 0,07395692 ! 5S class rRNA transcription GO:0042791 13 6 0,000 0,02058563 0,07384832 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,02058563 0,07374004 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 0,02058563 0,07363207 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 0,02058563 0,07352442 ! sodium ion homeostasis GO:0055078 12 6 0,000 0,02058563 0,07341709 ! establishment of spindle localization GO:0051293 16 6 0,000 0,02058563 0,07331006 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 0,02058563 0,07320335 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,02058563 0,07309695 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 0,000 0,02058563 0,07299086 ! response to UV-C GO:0010225 14 6 0,000 0,02058563 0,07288508 ! astrocyte development GO:0014002 16 6 0,000 0,02058563 0,0727796 ! protein targeting to lysosome GO:0006622 12 6 0,000 0,02058563 0,07267443 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,02058563 0,07256956 ! interaction with symbiont GO:0051702 14 6 0,000 0,02058563 0,07246499 ! regulation of dendrite development GO:0050773 16 6 0,000 0,02058563 0,07236073 ! peptidyl-arginine modification GO:0018195 13 6 0,000 0,02058563 0,07225676 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 0,02058563 0,07215309 ! response to copper ion GO:0046688 10 6 0,000 0,02058563 0,07204972 ! response to exogenous dsRNA GO:0043330 13 6 0,000 0,02058563 0,07194664 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 0,02058563 0,07184386 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,02058563 0,07174138 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 0,02058563 0,07163918 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,02058563 0,07153727 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 0,02058563 0,07143566 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,02058563 0,07133433 ! nucleoside catabolic process GO:0009164 10 6 0,000 0,02058563 0,07123329 ! hair follicle maturation GO:0048820 8 6 0,000 0,02058563 0,07113254 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,02058563 0,07103207 ! Schwann cell development GO:0014044 15 6 0,000 0,02058563 0,07093188 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 0,02058563 0,07083198 ! response to pheromone GO:0019236 6 6 0,000 0,02058563 0,07073235 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 0,02058563 0,07063301 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 0,02058563 0,07053395 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 0,02058563 0,07043516 ! base conversion or substitution editing GO:0016553 6 6 0,000 0,02058563 0,07033665 ! subpallium development GO:0021544 15 6 0,000 0,02058563 0,07023841 ! neural tube patterning GO:0021532 8 6 0,000 0,02058563 0,07014045 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 0,02058563 0,07004276 ! maintenance of organ identity GO:0048496 9 6 0,000 0,02058563 0,06994535 ! G2 phase GO:0051319 16 6 0,000 0,02058563 0,0698482 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 0,02058563 0,06975132 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 0,02058563 0,06965472 ! oxygen homeostasis GO:0032364 10 6 0,000 0,02058563 0,06955837 ! establishment of planar polarity GO:0001736 7 6 0,000 0,02058563 0,0694623 ! regulation of mast cell activation GO:0033003 13 6 0,000 0,02058563 0,06936649 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,02058563 0,06927094 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 0,02058563 0,06917566 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,02058563 0,06908064 ! receptor internalization GO:0031623 11 6 0,000 0,02058563 0,06898588 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 0,02058563 0,06889138 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 0,02058563 0,06879713 ! neutrophil homeostasis GO:0001780 11 6 0,000 0,02058563 0,06870315 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,02058563 0,06860942 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 0,02058563 0,06851595 ! protein deubiquitination GO:0016579 16 6 0,000 0,02058563 0,06842273 ! protein destabilization GO:0031648 9 6 0,000 0,02058563 0,06832976 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 0,02058563 0,06823705 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,02058563 0,06814459 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 0,02058563 0,06805237 ! regulation of viral transcription GO:0046782 11 6 0,000 0,02058563 0,06796041 ! progesterone metabolic process GO:0042448 12 6 0,000 0,02058563 0,0678687 ! negative regulation of axon extension GO:0030517 24 6 0,000 0,02058563 0,06777723 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 0,02058563 0,06768601 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 0,02058563 0,06759503 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,02058563 0,0675043 ! determination of adult lifespan GO:0008340 17 6 0,000 0,02058563 0,06741381 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,02058563 0,06732357 ! neural plate development GO:0001840 9 6 0,000 0,02058563 0,06723356 ! catecholamine transport GO:0051937 9 6 0,000 0,02058563 0,0671438 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 0,02058563 0,06705427 ! sensory cilium assembly GO:0035058 10 6 0,000 0,02058563 0,06696499 ! organ or tissue specific immune response GO:0002251 8 6 0,000 0,02058563 0,06687594 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 0,02058563 0,06678712 ! maternal placenta development GO:0001893 12 6 0,000 0,02058563 0,06669855 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 0,02058563 0,0666102 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,02058563 0,0665221 ! negative regulation of B cell activation GO:0050869 14 6 0,000 0,02058563 0,06643422 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 0,02058563 0,06634658 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 0,02058563 0,06625916 ! positive regulation of coagulation GO:0050820 13 6 0,000 0,02058563 0,06617198 ! cellular anion homeostasis GO:0030002 11 6 0,000 0,02058563 0,06608503 GO:0055081|anion homeostasis, ! multicellular organism reproduction GO:0032504 123 65 1,000 0,02143648 0,06872614 GO:0048609|reproductive process in a multicellular organism, ! gonad development GO:0008406 115 66 1,000 0,02205704 0,07062301 ! negative regulation of cell growth GO:0030308 142 67 1,000 0,02268501 0,07253857 ! activation of MAPK activity GO:0000187 124 67 1,000 0,02268501 0,07244375 ! viral reproduction GO:0016032 142 68 1,000 0,02332031 0,07437534 ! regulation of lipase activity GO:0060191 137 68 1,000 0,02332031 0,07427837 ! adaptive immune response GO:0002250 126 68 1,000 0,02332031 0,07418166 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! negative regulation of cell size GO:0045792 144 69 1,000 0,02396289 0,07612659 ! negative regulation of protein kinase activity GO:0006469 144 69 1,000 0,02396289 0,07602773 ! urogenital system development GO:0001655 149 69 1,000 0,02396289 0,07592912 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 1,000 0,02396289 0,07583076 ! developmental maturation GO:0021700 128 69 1,000 0,02396289 0,07573266 ! tRNA transcription GO:0009304 17 7 0,000 0,02397547 0,07567451 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 0,02397547 0,07557687 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 0,02397547 0,07547947 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,02397547 0,07538233 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 0,02397547 0,07528544 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,02397547 0,0751888 ! sleep GO:0030431 16 7 0,000 0,02397547 0,0750924 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,02397547 0,07499625 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 0,02397547 0,07490035 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,02397547 0,07480469 ! prostate gland development GO:0030850 14 7 0,000 0,02397547 0,07470928 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,02397547 0,0746141 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,02397547 0,07451918 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,02397547 0,07442449 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,02397547 0,07433004 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,02397547 0,07423583 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,02397547 0,07414186 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,02397547 0,07404813 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,02397547 0,07395464 ! SMAD protein complex assembly GO:0007183 13 7 0,000 0,02397547 0,07386138 ! glycolipid transport GO:0046836 11 7 0,000 0,02397547 0,07376835 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,02397547 0,07367556 GO:0051923|sulfation, ! neuron adhesion GO:0007158 14 7 0,000 0,02397547 0,073583 ! N-terminal protein amino acid acetylation GO:0006474 14 7 0,000 0,02397547 0,07349068 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,02397547 0,07339859 ! establishment of tissue polarity GO:0007164 8 7 0,000 0,02397547 0,07330672 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 0,02397547 0,07321509 ! pericardium development GO:0060039 16 7 0,000 0,02397547 0,07312369 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 0,02397547 0,07303251 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 0,02397547 0,07294156 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 0,02397547 0,07285084 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 0,02397547 0,07276034 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,02397547 0,07267006 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,02397547 0,07258001 ! lipoprotein transport GO:0042953 14 7 0,000 0,02397547 0,07249019 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,02397547 0,07240058 ! rhythmic behavior GO:0007622 17 7 0,000 0,02397547 0,0723112 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 0,02397547 0,07222204 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 0,02397547 0,07213309 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,02397547 0,07204437 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 0,02397547 0,07195586 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,02397547 0,07186757 ! regulation of odontogenesis GO:0042481 14 7 0,000 0,02397547 0,0717795 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,02397547 0,07169164 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 0,02397547 0,071604 ! mechanosensory behavior GO:0007638 16 7 0,000 0,02397547 0,07151657 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 0,02397547 0,07142936 ! positive regulation of isotype switching GO:0045830 17 7 0,000 0,02397547 0,07134235 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 0,02397547 0,07125556 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,02397547 0,07116898 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,02397547 0,07108261 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 0,02397547 0,07099645 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,02397547 0,0709105 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,02397547 0,07082475 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 0,02397547 0,07073922 ! adrenal gland development GO:0030325 17 7 0,000 0,02397547 0,07065389 ! cysteine metabolic process GO:0006534 13 7 0,000 0,02397547 0,07056876 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 0,02397547 0,07048384 ! ovulation GO:0030728 10 7 0,000 0,02397547 0,07039912 ! adenohypophysis development GO:0021984 11 7 0,000 0,02397547 0,07031461 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 0,02397547 0,0702303 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 0,02397547 0,07014619 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 0,02397547 0,07006229 ! microtubule nucleation GO:0007020 21 7 0,000 0,02397547 0,06997858 ! proline biosynthetic process GO:0006561 10 7 0,000 0,02397547 0,06989507 ! tryptophan metabolic process GO:0006568 11 7 0,000 0,02397547 0,06981177 ! thyroid hormone generation GO:0006590 13 7 0,000 0,02397547 0,06972866 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 0,02397547 0,06964575 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,02397547 0,06956303 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,02397547 0,06948051 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,02397547 0,06939819 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,02397547 0,06931606 ! galactose metabolic process GO:0006012 13 7 0,000 0,02397547 0,06923413 ! vesicle fusion GO:0006906 20 7 0,000 0,02397547 0,06915239 ! response to dietary excess GO:0002021 8 7 0,000 0,02397547 0,06907084 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,02397547 0,06898948 ! intracellular pH reduction GO:0051452 13 7 0,000 0,02397547 0,06890832 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,02397547 0,06882735 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 0,02397547 0,06874656 ! organ growth GO:0035265 15 7 0,000 0,02397547 0,06866597 ! nucleoside transport GO:0015858 11 7 0,000 0,02397547 0,06858556 ! nucleoside salvage GO:0043174 11 7 0,000 0,02397547 0,06850535 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 0,02397547 0,06842532 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,02397547 0,06834547 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 0,02397547 0,06826582 ! parturition GO:0007567 16 7 0,000 0,02397547 0,06818635 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 0,02397547 0,06810706 ! rRNA modification GO:0000154 14 7 0,000 0,02397547 0,06802796 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,02397547 0,06794904 ! spindle checkpoint GO:0031577 16 7 0,000 0,02397547 0,0678703 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 0,02397547 0,06779175 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,02397547 0,06771338 ! monocyte differentiation GO:0030224 16 7 0,000 0,02397547 0,06763519 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,02397547 0,06755718 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,02397547 0,06747935 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 0,02397547 0,06740169 ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,02397547 0,06732422 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,02397547 0,06724693 ! fibrinolysis GO:0042730 11 7 0,000 0,02397547 0,06716981 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 0,000 0,02397547 0,06709287 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,02397547 0,0670161 ! eating behavior GO:0042755 8 7 0,000 0,02397547 0,06693951 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,02397547 0,0668631 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 0,02397547 0,06678686 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 0,02397547 0,06671079 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,02397547 0,06663489 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,02397547 0,06655917 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 0,02397547 0,06648362 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 0,02397547 0,06640824 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 0,02397547 0,06633304 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,02397547 0,066258 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 0,02397547 0,06618313 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,02397547 0,06610843 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,02397547 0,0660339 ! histone ubiquitination GO:0016574 9 7 0,000 0,02397547 0,06595954 ! regulation of meiosis GO:0040020 12 7 0,000 0,02397547 0,06588535 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 0,02397547 0,06581132 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 0,02397547 0,06573745 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,02397547 0,06566376 ! membrane to membrane docking GO:0022614 14 7 0,000 0,02397547 0,06559023 ! transcription termination GO:0006353 14 7 0,000 0,02397547 0,06551686 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,02397547 0,06544366 ! peptidyl-histidine modification GO:0018202 17 7 0,000 0,02397547 0,06537062 ! axonal fasciculation GO:0007413 19 7 0,000 0,02397547 0,06529774 ! negative regulation of nuclear division GO:0051784 15 7 0,000 0,02397547 0,06522502 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 0,02397547 0,06515247 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,02397547 0,06508008 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 0,02397547 0,06500785 ! diuresis GO:0030146 12 7 0,000 0,02397547 0,06493578 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,02397547 0,06486387 ! thiamin metabolic process GO:0006772 7 7 0,000 0,02397547 0,06479211 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,02397547 0,06472052 ! antibiotic transport GO:0042891 9 7 0,000 0,02397547 0,06464909 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,02397547 0,06457781 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 0,02397547 0,06450669 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 0,02397547 0,06443572 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 0,02397547 0,06436491 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,02397547 0,06429426 ! melanin biosynthetic process GO:0042438 10 7 0,000 0,02397547 0,06422376 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 0,02397547 0,06415342 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,02397547 0,06408323 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,02397547 0,06401319 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 0,02397547 0,06394331 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,02397547 0,06387358 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 0,02397547 0,063804 ! endosome to lysosome transport GO:0008333 12 7 0,000 0,02397547 0,06373457 ! protein modification by small protein removal GO:0070646 19 7 0,000 0,02397547 0,0636653 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 0,02397547 0,06359617 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,02397547 0,06352719 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 0,02397547 0,06345837 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,02397547 0,06338969 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,02397547 0,06332116 ! muscle adaptation GO:0043500 13 7 0,000 0,02397547 0,06325278 ! embryonic heart tube development GO:0035050 14 7 0,000 0,02397547 0,06318454 ! retina homeostasis GO:0001895 12 7 0,000 0,02397547 0,06311646 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 0,02397547 0,06304852 ! protein amino acid prenylation GO:0018346 19 7 0,000 0,02397547 0,06298072 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 0,02397547 0,06291307 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 0,02397547 0,06284557 ! negative regulation of kinase activity GO:0033673 145 70 1,000 0,02461271 0,06444677 ! cell cycle checkpoint GO:0000075 145 71 1,000 0,02526969 0,06609619 ! B cell activation GO:0042113 179 72 1,000 0,02593378 0,06776066 ! regulation of caspase activity GO:0043281 136 74 1,000 0,02728308 0,07121 ! negative regulation of transferase activity GO:0051348 155 74 1,000 0,02728308 0,071134 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,02735367 0,07124201 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,02735367 0,07116614 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 0,02735367 0,07109044 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 0,02735367 0,07101489 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,02735367 0,0709395 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,02735367 0,07086427 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,02735367 0,0707892 ! male meiosis GO:0007140 9 8 0,000 0,02735367 0,0707143 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,02735367 0,07063954 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,02735367 0,07056495 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,02735367 0,07049052 ! meiotic prophase I GO:0007128 14 8 0,000 0,02735367 0,07041624 ! response to zinc ion GO:0010043 12 8 0,000 0,02735367 0,07034212 ! regulation of lipid kinase activity GO:0043550 17 8 0,000 0,02735367 0,07026815 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,02735367 0,07019434 ! oligopeptide transport GO:0006857 16 8 0,000 0,02735367 0,07012068 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,02735367 0,07004718 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,02735367 0,06997383 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,02735367 0,06990064 ! signal peptide processing GO:0006465 12 8 0,000 0,02735367 0,0698276 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,02735367 0,06975471 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,02735367 0,06968197 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,02735367 0,06960938 ! succinate metabolic process GO:0006105 17 8 0,000 0,02735367 0,06953695 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,02735367 0,06946467 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,02735367 0,06939253 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,02735367 0,06932055 ! estrogen metabolic process GO:0008210 17 8 0,000 0,02735367 0,06924871 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,02735367 0,06917703 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,02735367 0,06910549 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,02735367 0,0690341 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,02735367 0,06896286 ! reflex GO:0060004 17 8 0,000 0,02735367 0,06889176 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,02735367 0,06882081 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,02735367 0,06875001 ! hemoglobin metabolic process GO:0020027 14 8 0,000 0,02735367 0,06867935 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,02735367 0,06860884 ! pigment granule organization GO:0048753 17 8 0,000 0,02735367 0,06853847 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,02735367 0,06846825 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,02735367 0,06839817 ! astrocyte differentiation GO:0048708 19 8 0,000 0,02735367 0,06832823 ! histidine catabolic process GO:0006548 10 8 0,000 0,02735367 0,06825844 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,02735367 0,06818879 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,02735367 0,06811928 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,02735367 0,06804991 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,02735367 0,06798068 ! regulation of pigmentation during development GO:0048070 25 8 0,000 0,02735367 0,06791159 ! melanin metabolic process GO:0006582 17 8 0,000 0,02735367 0,06784265 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,02735367 0,06777384 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,02735367 0,06770518 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,02735367 0,06763665 ! macrophage activation GO:0042116 13 8 0,000 0,02735367 0,06756826 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,02735367 0,06750001 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,02735367 0,0674319 ! positive regulation of insulin secretion GO:0032024 17 8 0,000 0,02735367 0,06736392 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,02735367 0,06729608 ! purine salvage GO:0043101 12 8 0,000 0,02735367 0,06722838 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,02735367 0,06716081 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,02735367 0,06709338 ! osteoblast development GO:0002076 17 8 0,000 0,02735367 0,06702609 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,02735367 0,06695893 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,02735367 0,0668919 ! Schwann cell differentiation GO:0014037 21 8 0,000 0,02735367 0,06682501 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,02735367 0,06675825 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,02735367 0,06669163 ! response to UV-B GO:0010224 17 8 0,000 0,02735367 0,06662513 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,02735367 0,06655877 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,02735367 0,06649255 ! intermediate filament organization GO:0045109 12 8 0,000 0,02735367 0,06642645 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,02735367 0,06636049 ! cellular extravasation GO:0045123 13 8 0,000 0,02735367 0,06629465 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,02735367 0,06622895 ! response to antibiotic GO:0046677 11 8 0,000 0,02735367 0,06616338 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,02735367 0,06609793 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,02735367 0,06603262 ! DNA topological change GO:0006265 12 8 0,000 0,02735367 0,06596743 ! response to tropane GO:0014073 15 8 0,000 0,02735367 0,06590238 GO:0042220|response to cocaine, ! melanosome transport GO:0032402 13 8 0,000 0,02735367 0,06583745 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,02735367 0,06577265 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,02735367 0,06570797 ! mast cell activation GO:0045576 14 8 0,000 0,02735367 0,06564343 ! multicellular organismal aging GO:0010259 20 8 0,000 0,02735367 0,06557901 ! gas homeostasis GO:0033483 14 8 0,000 0,02735367 0,06551472 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,02735367 0,06545055 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,02735367 0,06538651 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,02735367 0,06532259 ! nucleosome disassembly GO:0006337 14 8 0,000 0,02735367 0,0652588 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,02735367 0,06519513 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 0,02735367 0,06513159 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,02735367 0,06506817 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,02735367 0,06500487 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,02735367 0,0649417 ! intracellular lipid transport GO:0032365 16 8 0,000 0,02735367 0,06487865 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,02735367 0,06481572 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,02735367 0,06475292 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 0,02735367 0,06469023 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,02735367 0,06462767 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 0,02735367 0,06456523 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,02735367 0,0645029 ! hormone catabolic process GO:0042447 17 8 0,000 0,02735367 0,0644407 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,02735367 0,06437862 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,02735367 0,06431666 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,02735367 0,06425482 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,02735367 0,06419309 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,02735367 0,06413149 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,02735367 0,06407 ! adult feeding behavior GO:0008343 10 8 0,000 0,02735367 0,06400863 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,02735367 0,06394738 ! ATP catabolic process GO:0006200 11 8 0,000 0,02735367 0,06388624 ! blastocyst growth GO:0001832 19 8 0,000 0,02735367 0,06382522 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,02735367 0,06376432 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,02735367 0,06370354 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,02735367 0,06364287 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,02735367 0,06358231 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,02735367 0,06352187 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,02735367 0,06346155 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,02735367 0,06340134 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,02735367 0,06334124 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,02735367 0,06328126 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 0,02735367 0,06322139 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,02735367 0,06316163 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 0,02735367 0,06310199 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,02735367 0,06304246 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,02735367 0,06298304 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 0,02735367 0,06292374 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 0,02735367 0,06286454 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,02735367 0,06280546 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 0,02735367 0,06274649 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 0,02735367 0,06268763 ! reproductive structure development GO:0048608 131 75 1,000 0,02796817 0,06403584 ! phosphoinositide-mediated signaling GO:0048015 141 75 1,000 0,02796817 0,06397588 ! eye development GO:0001654 155 75 1,000 0,02796817 0,06391604 ! axon guidance GO:0007411 162 75 1,000 0,02796817 0,0638563 ! rhythmic process GO:0048511 142 75 1,000 0,02796817 0,06379668 ! lymphocyte differentiation GO:0030098 193 76 1,000 0,02866015 0,06531414 ! phosphoinositide metabolic process GO:0030384 146 77 1,000 0,02935897 0,06684433 ! regulation of endopeptidase activity GO:0052548 141 77 1,000 0,02935897 0,06678209 ! regulation of vesicle-mediated transport GO:0060627 136 77 1,000 0,02935897 0,06671997 ! lipoprotein metabolic process GO:0042157 147 78 1,000 0,03006457 0,06825998 ! axon extension GO:0048675 16 9 0,000 0,03072027 0,06968395 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,03072027 0,06961931 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 0,03072027 0,06955479 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,03072027 0,06949038 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,03072027 0,0694261 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,03072027 0,06936193 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,03072027 0,06929789 ! reproductive behavior GO:0019098 22 9 0,000 0,03072027 0,06923396 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,03072027 0,06917015 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 0,03072027 0,06910646 GO:0010469|regulation of receptor activity, ! UTP metabolic process GO:0046051 10 9 0,000 0,03072027 0,06904288 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,03072027 0,06897942 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,03072027 0,06891608 ! artery development GO:0060840 25 9 0,000 0,03072027 0,06885286 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,03072027 0,06878975 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,03072027 0,06872675 ! equilibrioception GO:0050957 20 9 0,000 0,03072027 0,06866387 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,03072027 0,06860111 ! chemosensory behavior GO:0007635 21 9 0,000 0,03072027 0,06853846 ! microtubule bundle formation GO:0001578 22 9 0,000 0,03072027 0,06847592 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,03072027 0,0684135 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,03072027 0,0683512 ! leukocyte degranulation GO:0043299 16 9 0,000 0,03072027 0,068289 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,03072027 0,06822692 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,03072027 0,06816495 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,03072027 0,0681031 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,03072027 0,06804135 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,03072027 0,06797972 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,03072027 0,0679182 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,03072027 0,06785679 ! protein targeting to ER GO:0045047 25 9 0,000 0,03072027 0,0677955 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,03072027 0,06773431 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 0,03072027 0,06767323 ! T cell selection GO:0045058 27 9 0,000 0,03072027 0,06761226 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,03072027 0,06755141 ! glycine catabolic process GO:0006546 15 9 0,000 0,03072027 0,06749066 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,03072027 0,06743002 ! endosome organization GO:0007032 20 9 0,000 0,03072027 0,06736949 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,03072027 0,06730907 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,03072027 0,06724876 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,03072027 0,06718855 ! mannose metabolic process GO:0006013 13 9 0,000 0,03072027 0,06712846 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,03072027 0,06706847 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,03072027 0,06700858 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 0,03072027 0,06694881 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,03072027 0,06688914 ! receptor clustering GO:0043113 20 9 0,000 0,03072027 0,06682958 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,03072027 0,06677012 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,03072027 0,06671077 ! retinol metabolic process GO:0042572 20 9 0,000 0,03072027 0,06665152 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,03072027 0,06659238 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,03072027 0,06653335 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,03072027 0,06647441 ! macrophage differentiation GO:0030225 15 9 0,000 0,03072027 0,06641559 ! oligodendrocyte development GO:0014003 11 9 0,000 0,03072027 0,06635686 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 0,03072027 0,06629824 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,03072027 0,06623973 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,03072027 0,06618132 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,03072027 0,06612301 ! response to amine stimulus GO:0014075 13 9 0,000 0,03072027 0,0660648 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,03072027 0,0660067 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,03072027 0,06594869 ! erythrocyte development GO:0048821 17 9 0,000 0,03072027 0,06589079 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,03072027 0,06583299 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,03072027 0,0657753 ! renal water homeostasis GO:0003091 15 9 0,000 0,03072027 0,0657177 ! postreplication repair GO:0006301 25 9 0,000 0,03072027 0,0656602 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,03072027 0,06560281 ! icosanoid secretion GO:0032309 15 9 0,000 0,03072027 0,06554551 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,03072027 0,06548832 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,03072027 0,06543122 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,03072027 0,06537423 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,03072027 0,06531733 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,03072027 0,06526053 ! sterol catabolic process GO:0016127 14 9 0,000 0,03072027 0,06520383 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,03072027 0,06514723 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,03072027 0,06509073 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,03072027 0,06503433 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,03072027 0,06497802 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 0,03072027 0,06492181 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,03072027 0,0648657 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 0,03072027 0,06480968 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,03072027 0,06475376 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,03072027 0,06469794 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,03072027 0,06464222 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,03072027 0,06458659 ! purine base metabolic process GO:0006144 25 9 0,000 0,03072027 0,06453105 ! pigment granule transport GO:0051904 17 9 0,000 0,03072027 0,06447561 ! regulation of telomere maintenance GO:0032204 17 9 0,000 0,03072027 0,06442027 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,03072027 0,06436502 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,03072027 0,06430987 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,03072027 0,06425481 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,03072027 0,06419984 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,03072027 0,06414497 ! mitochondrion localization GO:0051646 18 9 0,000 0,03072027 0,06409019 ! response to steroid hormone stimulus GO:0048545 147 79 1,000 0,03077689 0,06415354 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 1,000 0,03149588 0,06559629 ! development of primary sexual characteristics GO:0045137 143 80 1,000 0,03149588 0,06554041 ! positive regulation of phosphorylation GO:0042327 149 81 1,000 0,03222149 0,06699328 ! regulation of peptidase activity GO:0052547 150 82 1,000 0,03295367 0,06845732 ! response to drug GO:0042493 149 83 1,000 0,03369235 0,06993238 ! cellular lipid catabolic process GO:0044242 150 83 1,000 0,03369235 0,06987302 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 1,000 0,03369235 0,06981375 GO:0045937|positive regulation of phosphate metabolic process, ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,03407531 0,07054744 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 0,000 0,03407531 0,07048771 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,03407531 0,07042807 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,03407531 0,07036854 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,03407531 0,0703091 ! associative learning GO:0008306 21 10 0,000 0,03407531 0,07024977 ! positive regulation of B cell proliferation GO:0030890 18 10 0,000 0,03407531 0,07019054 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,03407531 0,07013141 ! phosphate transport GO:0006817 24 10 0,000 0,03407531 0,07007237 ! cell volume homeostasis GO:0006884 17 10 0,000 0,03407531 0,07001344 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,03407531 0,06995461 ! CTP metabolic process GO:0046036 11 10 0,000 0,03407531 0,06989587 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 0,03407531 0,06983723 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,03407531 0,06977869 ! GTP metabolic process GO:0046039 11 10 0,000 0,03407531 0,06972025 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,03407531 0,06966191 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,03407531 0,06960366 ! social behavior GO:0035176 29 10 0,000 0,03407531 0,06954551 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,03407531 0,06948746 GO:0048200|Golgi transport vesicle coating, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,03407531 0,06942951 ! androgen metabolic process GO:0008209 17 10 0,000 0,03407531 0,06937165 ! phospholipid efflux GO:0033700 19 10 0,000 0,03407531 0,06931389 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,03407531 0,06925622 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,03407531 0,06919865 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,03407531 0,06914118 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,03407531 0,0690838 ! pathogenesis GO:0009405 17 10 0,000 0,03407531 0,06902652 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,03407531 0,06896933 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 0,03407531 0,06891224 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,03407531 0,06885524 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,03407531 0,06879833 ! endoderm development GO:0007492 18 10 0,000 0,03407531 0,06874152 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,03407531 0,0686848 ! arginine catabolic process GO:0006527 17 10 0,000 0,03407531 0,06862818 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,03407531 0,06857165 ! proline metabolic process GO:0006560 13 10 0,000 0,03407531 0,06851521 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,03407531 0,06845887 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 0,03407531 0,06840261 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,03407531 0,06834645 ! V(D)J recombination GO:0033151 34 10 0,000 0,03407531 0,06829039 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,03407531 0,06823441 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,03407531 0,06817853 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,03407531 0,06812273 ! B cell proliferation GO:0042100 19 10 0,000 0,03407531 0,06806703 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,03407531 0,06801142 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,03407531 0,0679559 ! multicellular organism growth GO:0035264 19 10 0,000 0,03407531 0,06790047 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,03407531 0,06784513 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,03407531 0,06778989 ! ruffle organization GO:0031529 17 10 0,000 0,03407531 0,06773473 ! epithelial cell development GO:0002064 21 10 0,000 0,03407531 0,06767966 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,03407531 0,06762468 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,03407531 0,06756979 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,03407531 0,06751499 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,03407531 0,06746028 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,03407531 0,06740565 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,03407531 0,06735112 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 13 10 0,000 0,03407531 0,06729667 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,03407531 0,06724231 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,03407531 0,06718804 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,03407531 0,06713385 ! segment specification GO:0007379 15 10 0,000 0,03407531 0,06707976 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,03407531 0,06702575 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 0,000 0,03407531 0,06697183 ! blastoderm segmentation GO:0007350 19 10 0,000 0,03407531 0,06691799 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,03407531 0,06686424 ! response to dsRNA GO:0043331 23 10 0,000 0,03407531 0,06681058 ! DNA ligation GO:0006266 18 10 0,000 0,03407531 0,066757 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,03407531 0,06670351 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,03407531 0,0666501 ! melanosome localization GO:0032400 16 10 0,000 0,03407531 0,06659678 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,03407531 0,06654355 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,03407531 0,0664904 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,03407531 0,06643733 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,03407531 0,06638435 ! induction of an organ GO:0001759 17 10 0,000 0,03407531 0,06633146 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,03407531 0,06627865 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,03407531 0,06622592 ! protein sumoylation GO:0016925 17 10 0,000 0,03407531 0,06617328 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,03407531 0,06612071 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,03407531 0,06606824 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,03407531 0,06601584 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,03407531 0,06596353 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,03407531 0,06591131 ! salivary gland development GO:0007431 28 10 0,000 0,03407531 0,06585916 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,03407531 0,0658071 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,03407531 0,06575512 ! musculoskeletal movement GO:0050881 16 10 0,000 0,03407531 0,06570322 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,03407531 0,0656514 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,03407531 0,06559967 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,03407531 0,06554802 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,03407531 0,06549644 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,03407531 0,06544495 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,03407531 0,06539354 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,03407531 0,06534221 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,03407531 0,06529096 ! detection of calcium ion GO:0005513 24 10 0,000 0,03407531 0,0652398 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,03407531 0,06518871 ! blastocyst formation GO:0001825 18 10 0,000 0,03407531 0,0651377 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,03407531 0,06508677 ! cerebellar cortex development GO:0021695 16 10 0,000 0,03407531 0,06503592 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,03407531 0,06498515 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,03407531 0,06493446 ! response to nicotine GO:0035094 20 10 0,000 0,03407531 0,06488385 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,03407531 0,06483332 ! T cell activation GO:0042110 189 84 1,000 0,03443749 0,06547143 ! negative regulation of transport GO:0051051 164 85 1,000 0,03518904 0,06684822 ! mitochondrion organization GO:0007005 159 87 1,000 0,03671113 0,06968554 ! negative regulation of muscle development GO:0048635 27 11 0,000 0,03741883 0,07097376 ! respiratory burst GO:0045730 17 11 0,000 0,03741883 0,0709187 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,03741883 0,07086373 ! telencephalon cell migration GO:0022029 23 11 0,000 0,03741883 0,07080884 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,03741883 0,07075403 ! thyroid gland development GO:0030878 26 11 0,000 0,03741883 0,07069931 ! synapsis GO:0007129 14 11 0,000 0,03741883 0,07064467 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,03741883 0,07059012 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,03741883 0,07053565 ! response to pain GO:0048265 27 11 0,000 0,03741883 0,07048127 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,03741883 0,07042697 ! bone resorption GO:0045453 16 11 0,000 0,03741883 0,07037275 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,03741883 0,07031862 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,03741883 0,07026457 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,03741883 0,0702106 ! melanocyte differentiation GO:0030318 20 11 0,000 0,03741883 0,07015672 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,03741883 0,07010292 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,03741883 0,0700492 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,03741883 0,06999556 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,03741883 0,06994201 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,03741883 0,06988854 ! UV protection GO:0009650 20 11 0,000 0,03741883 0,06983515 ! adult heart development GO:0007512 16 11 0,000 0,03741883 0,06978184 ! chondrocyte differentiation GO:0002062 27 11 0,000 0,03741883 0,06972861 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,03741883 0,06967546 ! macroautophagy GO:0016236 19 11 0,000 0,03741883 0,0696224 ! temperature homeostasis GO:0001659 18 11 0,000 0,03741883 0,06956941 ! behavioral fear response GO:0001662 27 11 0,000 0,03741883 0,06951651 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,03741883 0,06946368 ! negative regulation of ossification GO:0030279 27 11 0,000 0,03741883 0,06941094 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,03741883 0,06935827 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 0,03741883 0,06930569 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,03741883 0,06925319 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,03741883 0,06920076 ! regulation of organ growth GO:0046620 14 11 0,000 0,03741883 0,06914842 ! pigment granule localization GO:0051875 20 11 0,000 0,03741883 0,06909615 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,03741883 0,06904396 ! vasoconstriction GO:0042310 20 11 0,000 0,03741883 0,06899185 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,03741883 0,06893982 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,03741883 0,06888787 ! embryonic axis specification GO:0000578 19 11 0,000 0,03741883 0,068836 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,03741883 0,0687842 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,03741883 0,06873249 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,03741883 0,06868085 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,03741883 0,06862928 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,03741883 0,0685778 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,03741883 0,06852639 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,03741883 0,06847506 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,03741883 0,06842381 ! prophase GO:0051324 17 11 0,000 0,03741883 0,06837263 ! neuroblast proliferation GO:0007405 25 11 0,000 0,03741883 0,06832153 ! nucleosome positioning GO:0016584 15 11 0,000 0,03741883 0,0682705 ! regulation of isotype switching GO:0045191 24 11 0,000 0,03741883 0,06821956 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,03741883 0,06816868 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,03741883 0,06811789 ! apical protein localization GO:0045176 18 11 0,000 0,03741883 0,06806717 ! acid secretion GO:0046717 20 11 0,000 0,03741883 0,06801652 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,03741883 0,06796595 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,03741883 0,06791546 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,03741883 0,06786504 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,03741883 0,06781469 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,03741883 0,06776442 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 0,03741883 0,06771423 ! cholesterol efflux GO:0033344 21 11 0,000 0,03741883 0,06766411 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,03741883 0,06761406 ! oocyte development GO:0048599 20 11 0,000 0,03741883 0,06756408 ! negative regulation of glucose import GO:0046325 18 11 0,000 0,03741883 0,06751418 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 26 11 0,000 0,03741883 0,06746436 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,03741883 0,06741461 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,03741883 0,06736493 ! activation of innate immune response GO:0002218 16 11 0,000 0,03741883 0,06731532 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,03741883 0,06726579 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,03741883 0,06721633 ! lysogeny GO:0030069 22 11 0,000 0,03741883 0,06716694 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,03741883 0,06711763 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,03741883 0,06706838 ! sequestering of metal ion GO:0051238 15 11 0,000 0,03741883 0,06701921 ! nucleus localization GO:0051647 22 11 0,000 0,03741883 0,06697011 ! one-carbon metabolic process GO:0006730 167 88 1,000 0,03748157 0,0670333 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,04075087 0,07282691 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,04075087 0,07277367 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,04075087 0,07272052 ! regulation of B cell proliferation GO:0030888 22 12 0,000 0,04075087 0,07266744 ! mating GO:0007618 17 12 0,000 0,04075087 0,07261443 ! protein complex disassembly GO:0043241 28 12 0,000 0,04075087 0,07256151 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,04075087 0,07250866 ! regulation of cell projection assembly GO:0060491 33 12 0,000 0,04075087 0,07245589 ! hippocampus development GO:0021766 29 12 0,000 0,04075087 0,07240319 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 0,000 0,04075087 0,07235057 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,04075087 0,07229803 ! T cell proliferation GO:0042098 32 12 0,000 0,04075087 0,07224556 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,04075087 0,07219317 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,04075087 0,07214086 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,04075087 0,07208862 ! drug transport GO:0015893 16 12 0,000 0,04075087 0,07203646 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,04075087 0,07198437 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,04075087 0,07193236 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,04075087 0,07188042 ! polyamine metabolic process GO:0006595 18 12 0,000 0,04075087 0,07182856 ! focal adhesion formation GO:0048041 37 12 0,000 0,04075087 0,07177678 ! mitotic spindle organization GO:0007052 23 12 0,000 0,04075087 0,07172506 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,04075087 0,07167342 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,04075087 0,07162186 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,04075087 0,07157037 ! lipid digestion GO:0044241 21 12 0,000 0,04075087 0,07151896 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,04075087 0,07146761 ! entry into host cell GO:0030260 34 12 0,000 0,04075087 0,07141635 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,04075087 0,07136515 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,04075087 0,07131403 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,04075087 0,07126298 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,04075087 0,07121201 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,04075087 0,07116111 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,04075087 0,07111028 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,04075087 0,07105952 ! snRNA metabolic process GO:0016073 30 12 0,000 0,04075087 0,07100884 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,04075087 0,07095822 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,04075087 0,07090768 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,04075087 0,07085722 ! fucose catabolic process GO:0019317 25 12 0,000 0,04075087 0,07080682 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,04075087 0,07075649 ! histone acetylation GO:0016573 27 12 0,000 0,04075087 0,07070624 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,04075087 0,07065606 ! autonomic nervous system development GO:0048483 24 12 0,000 0,04075087 0,07060595 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 0,04075087 0,07055591 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,04075087 0,07050594 ! T cell homeostasis GO:0043029 28 12 0,000 0,04075087 0,07045604 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,04075087 0,07040621 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,04075087 0,07035646 ! oocyte differentiation GO:0009994 21 12 0,000 0,04075087 0,07030677 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,04075087 0,07025715 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,04075087 0,07020761 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,04075087 0,07015813 ! defense response to fungus GO:0050832 15 12 0,000 0,04075087 0,07010872 ! developmental induction GO:0031128 22 12 0,000 0,04075087 0,07005939 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 21 12 0,000 0,04075087 0,07001012 ! lamellipodium assembly GO:0030032 24 12 0,000 0,04075087 0,06996092 ! response to cold GO:0009409 17 12 0,000 0,04075087 0,06991179 ! establishment of cell polarity GO:0030010 21 12 0,000 0,04075087 0,06986273 ! regulation of synapse organization GO:0050807 18 12 0,000 0,04075087 0,06981374 ! regulation of cell morphogenesis GO:0022604 243 93 1,000 0,04142571 0,07092013 ! carbohydrate biosynthetic process GO:0016051 158 94 1,000 0,04223257 0,07225082 ! regulation of membrane potential GO:0042391 179 94 1,000 0,04223257 0,07220026 ! sex differentiation GO:0007548 171 96 1,000 0,04386391 0,07493674 ! regulation of T cell activation GO:0050863 175 96 1,000 0,04386391 0,07488437 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,04407148 0,07518619 ! cGMP metabolic process GO:0046068 18 13 0,000 0,04407148 0,07513372 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,04407148 0,07508132 ! regulation of chemokine production GO:0032642 18 13 0,000 0,04407148 0,075029 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,04407148 0,07497675 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,04407148 0,07492458 ! peroxisomal transport GO:0043574 28 13 0,000 0,04407148 0,07487247 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,04407148 0,07482044 ! cartilage condensation GO:0001502 22 13 0,000 0,04407148 0,07476849 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,04407148 0,0747166 ! organelle fusion GO:0048284 36 13 0,000 0,04407148 0,07466478 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,04407148 0,07461304 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,04407148 0,07456137 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,04407148 0,07450977 ! endocrine pancreas development GO:0031018 25 13 0,000 0,04407148 0,07445824 ! positive regulation of cell growth GO:0030307 24 13 0,000 0,04407148 0,07440679 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,04407148 0,0743554 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,04407148 0,07430408 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,04407148 0,07425284 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,04407148 0,07420167 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,04407148 0,07415056 ! methionine metabolic process GO:0006555 31 13 0,000 0,04407148 0,07409953 ! plasma membrane organization GO:0007009 27 13 0,000 0,04407148 0,07404857 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,04407148 0,07399768 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,04407148 0,07394685 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,04407148 0,0738961 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,04407148 0,07384542 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! cytokine metabolic process GO:0042107 24 13 0,000 0,04407148 0,0737948 ! cellular carbohydrate catabolic process GO:0044275 17 13 0,000 0,04407148 0,07374426 ! exocrine system development GO:0035272 34 13 0,000 0,04407148 0,07369378 ! asymmetric protein localization GO:0008105 24 13 0,000 0,04407148 0,07364338 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,04407148 0,07359304 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 0,04407148 0,07354277 ! L-glutamate transport GO:0015813 30 13 0,000 0,04407148 0,07349257 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,04407148 0,07344244 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,04407148 0,07339238 ! protein homotetramerization GO:0051289 24 13 0,000 0,04407148 0,07334238 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,04407148 0,07329246 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,04407148 0,0732426 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,04407148 0,07319281 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,04407148 0,07314308 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,04407148 0,07309343 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,04407148 0,07304384 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,04407148 0,07299432 ! histone methylation GO:0016571 29 13 0,000 0,04407148 0,07294486 ! chromatin silencing GO:0006342 29 13 0,000 0,04407148 0,07289548 ! gland morphogenesis GO:0022612 31 13 0,000 0,04407148 0,07284616 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,04407148 0,0727969 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 0,04407148 0,07274772 ! regulation of epidermis development GO:0045682 19 13 0,000 0,04407148 0,07269859 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,04407148 0,07264954 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,04407148 0,07260055 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,04407148 0,07255163 ! spleen development GO:0048536 24 13 0,000 0,04407148 0,07250277 ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,04407148 0,07245398 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,04407148 0,07240526 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,04407148 0,0723566 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,04407148 0,072308 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,04407148 0,07225948 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,04407148 0,07221101 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,04407148 0,07216261 ! insulin secretion GO:0030073 24 13 0,000 0,04407148 0,07211428 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,04407148 0,07206601 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 0,04407148 0,07201781 ! acrosome reaction GO:0007340 19 13 0,000 0,04407148 0,07196966 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,04407148 0,07192159 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,04407148 0,07187358 ! leukocyte differentiation GO:0002521 232 98 1,000 0,04551842 0,0741838 ! interphase of mitotic cell cycle GO:0051329 224 98 1,000 0,04551842 0,07413434 ! forebrain development GO:0030900 210 98 1,000 0,04551842 0,07408495 ! skeletal muscle tissue development GO:0007519 223 100 1,000 0,04719572 0,07676374 GO:0060538|skeletal muscle organ development, ! rRNA transcription GO:0009303 28 14 0,000 0,04738068 0,0770133 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,04738068 0,0769621 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 0,04738068 0,07691096 ! water transport GO:0006833 21 14 0,000 0,04738068 0,07685989 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,04738068 0,07680889 ! non-recombinational repair GO:0000726 29 14 0,000 0,04738068 0,07675795 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,04738068 0,07670709 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,04738068 0,07665629 ! RNA polyadenylation GO:0043631 32 14 0,000 0,04738068 0,07660556 ! lipid localization GO:0010876 32 14 0,000 0,04738068 0,07655489 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 0,04738068 0,07650429 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 0,000 0,04738068 0,07645376 ! regulated secretory pathway GO:0045055 24 14 0,000 0,04738068 0,0764033 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,04738068 0,0763529 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,04738068 0,07630257 ! arginine metabolic process GO:0006525 21 14 0,000 0,04738068 0,0762523 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,04738068 0,0762021 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,04738068 0,07615197 ! regulation of heart rate GO:0002027 25 14 0,000 0,04738068 0,0761019 ! fear response GO:0042596 34 14 0,000 0,04738068 0,0760519 ! organic alcohol transport GO:0015850 29 14 0,000 0,04738068 0,07600197 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,04738068 0,0759521 ! embryo implantation GO:0007566 30 14 0,000 0,04738068 0,07590229 ! neutral amino acid transport GO:0015804 28 14 0,000 0,04738068 0,07585255 ! bone mineralization GO:0030282 18 14 0,000 0,04738068 0,07580288 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,04738068 0,07575327 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,04738068 0,07570373 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,04738068 0,07565425 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,04738068 0,07560483 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,04738068 0,07555548 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,04738068 0,07550619 ! ribosome assembly GO:0042255 18 14 0,000 0,04738068 0,07545697 ! cerebellum development GO:0021549 23 14 0,000 0,04738068 0,07540781 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,04738068 0,07535872 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,04738068 0,07530969 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,04738068 0,07526073 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,04738068 0,07521182 ! NADP metabolic process GO:0006739 24 14 0,000 0,04738068 0,07516298 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,04738068 0,07511421 ! oxygen transport GO:0015671 22 14 0,000 0,04738068 0,0750655 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,04738068 0,07501685 ! male genitalia development GO:0030539 26 14 0,000 0,04738068 0,07496826 ! regulation of axon extension GO:0030516 43 14 0,000 0,04738068 0,07491974 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,04738068 0,07487128 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 0,04738068 0,07482288 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,05067852 0,07997908 ! lactation GO:0007595 30 15 0,000 0,05067852 0,07992745 ! reproductive cellular process GO:0048610 22 15 0,000 0,05067852 0,07987588 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,05067852 0,07982438 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,05067852 0,07977295 ! superoxide anion generation GO:0042554 22 15 0,000 0,05067852 0,07972158 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,05067852 0,07967028 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,05067852 0,07961904 ! copper ion transport GO:0006825 22 15 0,000 0,05067852 0,07956788 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,05067852 0,07951677 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,05067852 0,07946573 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,05067852 0,07941476 ! sulfate transport GO:0008272 27 15 0,000 0,05067852 0,07936385 ! response to cAMP GO:0051591 25 15 0,000 0,05067852 0,07931301 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,05067852 0,07926224 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,05067852 0,07921153 ! response to hexose stimulus GO:0009746 25 15 0,000 0,05067852 0,07916088 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,05067852 0,0791103 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,05067852 0,07905978 ! vesicle coating GO:0006901 38 15 0,000 0,05067852 0,07900933 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 0,05067852 0,07895894 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 0,05067852 0,07890861 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,05067852 0,07885835 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,05067852 0,07880816 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,05067852 0,07875802 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,05067852 0,07870796 ! regulation of vasodilation GO:0042312 27 15 0,000 0,05067852 0,07865795 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,05067852 0,07860801 ! histone deacetylation GO:0016575 24 15 0,000 0,05067852 0,07855813 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,05067852 0,07850832 ! water homeostasis GO:0030104 28 15 0,000 0,05067852 0,07845856 ! cofactor transport GO:0051181 30 15 0,000 0,05067852 0,07840887 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,05067852 0,07835925 ! muscle maintenance GO:0046716 26 15 0,000 0,05067852 0,07830969 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,05067852 0,07826019 ! intestinal absorption GO:0050892 31 15 0,000 0,05067852 0,07821075 ! dopamine metabolic process GO:0042417 35 15 0,000 0,05067852 0,07816137 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,05067852 0,07811206 ! heme biosynthetic process GO:0006783 33 15 0,000 0,05067852 0,07806281 ! cell killing GO:0001906 32 15 0,000 0,05067852 0,07801362 ! lymphocyte homeostasis GO:0002260 33 15 0,000 0,05067852 0,07796449 ! epithelial to mesenchymal transition GO:0001837 30 15 0,000 0,05067852 0,07791543 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,05067852 0,07786642 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,05067852 0,07781748 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,05067852 0,0777686 ! actin filament polymerization GO:0030041 27 15 0,000 0,05067852 0,07771978 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,05067852 0,07767102 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,05396503 0,08265615 ! positive regulation of cell size GO:0045793 29 16 0,000 0,05396503 0,08260436 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,05396503 0,08255264 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,05396503 0,08250098 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,05396503 0,08244938 ! bone remodeling GO:0046849 28 16 0,000 0,05396503 0,08239785 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,05396503 0,08234639 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,05396503 0,08229499 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,05396503 0,08224365 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,05396503 0,08219237 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,05396503 0,08214116 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,05396503 0,08209002 ! startle response GO:0001964 28 16 0,000 0,05396503 0,08203893 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,05396503 0,08198791 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,05396503 0,08193696 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,05396503 0,08188607 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,05396503 0,08183524 ! protein polyubiquitination GO:0000209 41 16 0,000 0,05396503 0,08178447 ! glutamate metabolic process GO:0006536 25 16 0,000 0,05396503 0,08173377 ! pituitary gland development GO:0021983 30 16 0,000 0,05396503 0,08168313 ! response to osmotic stress GO:0006970 27 16 0,000 0,05396503 0,08163255 ! lysosomal transport GO:0007041 31 16 0,000 0,05396503 0,08158203 ! fructose metabolic process GO:0006000 25 16 0,000 0,05396503 0,08153158 ! L-amino acid transport GO:0015807 33 16 0,000 0,05396503 0,08148119 ! stem cell development GO:0048864 46 16 0,000 0,05396503 0,08143086 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,05396503 0,0813806 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,05396503 0,08133039 ! intermediate filament-based process GO:0045103 36 16 0,000 0,05396503 0,08128025 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,05396503 0,08123017 ! negative regulation of immune response GO:0050777 38 16 0,000 0,05396503 0,08118015 ! axon cargo transport GO:0008088 46 16 0,000 0,05396503 0,08113019 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,05396503 0,0810803 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,05396503 0,08103046 ! DNA replication initiation GO:0006270 28 16 0,000 0,05396503 0,08098069 ! neuron recognition GO:0008038 40 16 0,000 0,05396503 0,08093098 ! mRNA splice site selection GO:0006376 44 16 0,000 0,05396503 0,08088133 ! tissue regeneration GO:0042246 27 16 0,000 0,05396503 0,08083174 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,05396503 0,08078221 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,05396503 0,08073274 ! biomineral formation GO:0031214 22 16 0,000 0,05396503 0,08068333 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,05396503 0,08063399 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,05396503 0,0805847 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,05396503 0,08053547 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,05396503 0,0804863 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,05396503 0,0804372 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,05396503 0,08038815 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,05396503 0,08033916 ! peptide hormone processing GO:0016486 27 16 0,000 0,05396503 0,08029024 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,05724026 0,08511135 ! metencephalon development GO:0022037 32 17 0,000 0,05724026 0,08505958 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,05724026 0,08500787 ! negative regulation of cell cycle process GO:0010948 35 17 0,000 0,05724026 0,08495623 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,05724026 0,08490464 ! signal complex assembly GO:0007172 47 17 0,000 0,05724026 0,08485312 ! filopodium assembly GO:0046847 42 17 0,000 0,05724026 0,08480167 ! endothelial cell migration GO:0043542 31 17 0,000 0,05724026 0,08475027 ! gene silencing by RNA GO:0031047 38 17 0,000 0,05724026 0,08469894 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,05724026 0,08464767 ! glial cell development GO:0021782 28 17 0,000 0,05724026 0,08459646 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,05724026 0,08454531 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,05724026 0,08449423 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,05724026 0,08444321 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 0,000 0,05724026 0,08439224 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,05724026 0,08434134 ! myoblast differentiation GO:0045445 50 17 0,000 0,05724026 0,08429051 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,05724026 0,08423973 ! regulation of survival gene product expression GO:0045884 38 17 0,000 0,05724026 0,08418901 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,05724026 0,08413836 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,05724026 0,08408776 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,05724026 0,08403723 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,05724026 0,08398676 ! negative regulation of microtubule depolymerization GO:0007026 50 17 0,000 0,05724026 0,08393634 GO:0031114|regulation of microtubule depolymerization, ! NAD metabolic process GO:0019674 33 17 0,000 0,05724026 0,08388599 ! membrane budding GO:0006900 42 17 0,000 0,05724026 0,0838357 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,05724026 0,08378547 ! regulation of protein binding GO:0043393 33 17 0,000 0,05724026 0,0837353 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,05724026 0,08368519 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,05724026 0,08363514 ! genitalia development GO:0048806 32 17 0,000 0,05724026 0,08358515 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,05724026 0,08353521 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 0,000 0,05724026 0,08348534 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,05724026 0,08343553 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,05724026 0,08338578 ! neutrophil chemotaxis GO:0030593 29 17 0,000 0,05724026 0,08333608 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,05724026 0,08328645 ! steroid catabolic process GO:0006706 34 17 0,000 0,05724026 0,08323687 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,05724026 0,08318736 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,05724026 0,0831379 ! gas transport GO:0015669 26 17 0,000 0,05724026 0,0830885 ! organic cation transport GO:0015695 32 17 0,000 0,05724026 0,08303916 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,05724026 0,08298988 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,05724026 0,08294066 ! positive regulation of protein complex assembly GO:0031334 34 18 0,000 0,06050424 0,08761817 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,06050424 0,08756626 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,06050424 0,08751442 ! limbic system development GO:0021761 40 18 0,000 0,06050424 0,08746264 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,06050424 0,08741091 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,06050424 0,08735925 ! adult walking behavior GO:0007628 36 18 0,000 0,06050424 0,08730765 ! patterning of blood vessels GO:0001569 43 18 0,000 0,06050424 0,08725611 ! heart looping GO:0001947 34 18 0,000 0,06050424 0,08720463 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,06050424 0,08715322 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,06050424 0,08710186 ! centrosome cycle GO:0007098 26 18 0,000 0,06050424 0,08705056 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,06050424 0,08699933 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,06050424 0,08694815 ! glycine metabolic process GO:0006544 30 18 0,000 0,06050424 0,08689703 ! glutamine metabolic process GO:0006541 29 18 0,000 0,06050424 0,08684598 ! response to retinoic acid GO:0032526 31 18 0,000 0,06050424 0,08679498 ! cell-substrate junction assembly GO:0007044 56 18 0,000 0,06050424 0,08674405 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,06050424 0,08669317 ! DNA integration GO:0015074 32 18 0,000 0,06050424 0,08664235 ! negative regulation of protein catabolic process GO:0042177 42 18 0,000 0,06050424 0,0865916 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,06050424 0,0865409 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,06050424 0,08649026 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,06050424 0,08643968 ! neural crest cell migration GO:0001755 41 18 0,000 0,06050424 0,08638916 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,06050424 0,0863387 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,06050424 0,0862883 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,06050424 0,08623795 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,06050424 0,08618767 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,06050424 0,08613744 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,06050424 0,08608728 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,06050424 0,08603717 ! detection of bacterium GO:0016045 22 18 0,000 0,06050424 0,08598712 ! defense response to virus GO:0051607 43 18 0,000 0,06050424 0,08593712 ! microspike assembly GO:0030035 46 18 0,000 0,06050424 0,08588719 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,06050424 0,08583731 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 0,000 0,06050424 0,08578749 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,06375701 0,09034709 ! positive regulation of translation GO:0045727 31 19 0,000 0,06375701 0,09029471 ! negative regulation of defense response GO:0031348 27 19 0,000 0,06375701 0,0902424 ! G1 phase of mitotic cell cycle GO:0000080 39 19 0,000 0,06375701 0,09019014 ! neuron maturation GO:0042551 46 19 0,000 0,06375701 0,09013795 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,06375701 0,09008582 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 0,06375701 0,09003374 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,06375701 0,08998173 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,06375701 0,08992978 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,06375701 0,08987789 ! inositol metabolic process GO:0006020 33 19 0,000 0,06375701 0,08982605 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,06375701 0,08977428 ! memory GO:0007613 34 19 0,000 0,06375701 0,08972257 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,06375701 0,08967091 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,06375701 0,08961932 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,06375701 0,08956778 ! cerebral cortex development GO:0021987 40 19 0,000 0,06375701 0,08951631 ! pigmentation during development GO:0048066 42 19 0,000 0,06375701 0,08946489 ! response to vitamin A GO:0033189 32 19 0,000 0,06375701 0,08941353 ! heme metabolic process GO:0042168 40 19 0,000 0,06375701 0,08936224 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,06375701 0,089311 ! response to fungus GO:0009620 26 19 0,000 0,06375701 0,08925981 ! peptide cross-linking GO:0018149 39 19 0,000 0,06375701 0,08920869 ! protein export from nucleus GO:0006611 40 19 0,000 0,06375701 0,08915763 ! heart process GO:0003015 32 19 0,000 0,06375701 0,08910662 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,06375701 0,08905568 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,06375701 0,08900479 ! visual learning GO:0008542 38 19 0,000 0,06375701 0,08895396 ! cellular pigmentation GO:0033059 37 19 0,000 0,06375701 0,08890318 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,06375701 0,08885247 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,06375701 0,08880181 ! vitamin transport GO:0051180 31 19 0,000 0,06375701 0,08875121 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,06375701 0,08870067 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,06375701 0,08865019 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,06375701 0,08859976 ! cilium assembly GO:0042384 38 19 0,000 0,06375701 0,08854939 ! peptide hormone secretion GO:0030072 32 19 0,000 0,06375701 0,08849908 ! protein secretion GO:0009306 45 20 0,000 0,06699861 0,09294583 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,06699861 0,09289308 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,06699861 0,09284039 ! positive regulation of ossification GO:0045778 50 20 0,000 0,06699861 0,09278776 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,06699861 0,09273519 ! skin development GO:0043588 42 20 0,000 0,06699861 0,09268268 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,06699861 0,09263023 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,06699861 0,09257783 ! protein amino acid acetylation GO:0006473 41 20 0,000 0,06699861 0,0925255 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,06699861 0,09247322 ! response to vitamin GO:0033273 36 20 0,000 0,06699861 0,09242101 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,06699861 0,09236885 ! forelimb morphogenesis GO:0035136 35 20 0,000 0,06699861 0,09231676 ! bile acid metabolic process GO:0008206 34 20 0,000 0,06699861 0,09226472 ! response to alkaloid GO:0043279 38 20 0,000 0,06699861 0,09221274 ! retinoid metabolic process GO:0001523 34 20 0,000 0,06699861 0,09216082 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 40 20 0,000 0,06699861 0,09210895 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,06699861 0,09205715 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,06699861 0,0920054 GO:0032392|DNA geometric change, ! cellular response to unfolded protein GO:0034620 35 20 0,000 0,06699861 0,09195371 GO:0030968|endoplasmic reticulum unfolded protein response, ! actin filament bundle formation GO:0051017 47 20 0,000 0,06699861 0,09190208 ! body fluid secretion GO:0007589 33 20 0,000 0,06699861 0,09185051 ! peptide secretion GO:0002790 38 20 0,000 0,06699861 0,09179899 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,06699861 0,09174754 ! regulation of fatty acid metabolic process GO:0019217 45 20 0,000 0,06699861 0,09169614 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,06699861 0,0916448 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,06699861 0,09159351 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,06699861 0,09154229 ! cell-cell junction organization GO:0045216 43 20 0,000 0,06699861 0,09149112 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 0,000 0,06699861 0,09144 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,06699861 0,09138895 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,06699861 0,09133795 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,06699861 0,09128701 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,06699861 0,09123612 ! regulation of glucose import GO:0046324 30 20 0,000 0,06699861 0,0911853 GO:0010827|regulation of glucose transport, ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,06699861 0,09113453 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,06699861 0,09108381 ! negative regulation of translation GO:0017148 32 20 0,000 0,06699861 0,09103315 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,06699861 0,09098255 ! regulation of cell killing GO:0031341 46 21 0,000 0,07022908 0,09531647 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,07022908 0,09526354 ! hormone secretion GO:0046879 39 21 0,000 0,07022908 0,09521068 ! cAMP metabolic process GO:0046058 41 21 0,000 0,07022908 0,09515787 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,07022908 0,09510512 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,07022908 0,09505243 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,07022908 0,0949998 ! smooth muscle contraction GO:0006939 48 21 0,000 0,07022908 0,09494723 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,07022908 0,09489471 ! cell structure disassembly during apoptosis GO:0006921 32 21 0,000 0,07022908 0,09484226 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,07022908 0,09478986 ! plasma membrane fusion GO:0045026 33 21 0,000 0,07022908 0,09473752 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,07022908 0,09468523 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,07022908 0,09463301 GO:0006692|prostanoid metabolic process, ! regulation of vasoconstriction GO:0019229 40 21 0,000 0,07022908 0,09458084 ! sensory perception of pain GO:0019233 33 21 0,000 0,07022908 0,09452873 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,07022908 0,09447668 ! diencephalon development GO:0021536 36 21 0,000 0,07022908 0,09442468 ! collagen fibril organization GO:0030199 62 21 0,000 0,07022908 0,09437274 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,07022908 0,09432086 ! positive regulation of inflammatory response GO:0050729 41 21 0,000 0,07022908 0,09426903 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,07022908 0,09421727 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,07022908 0,09416556 GO:0043450|alkene biosynthetic process, ! sperm-egg recognition GO:0035036 23 21 0,000 0,07022908 0,0941139 ! actin filament-based movement GO:0030048 47 21 0,000 0,07022908 0,0940623 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,07344845 0,09832031 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,07344845 0,09826647 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,07344845 0,09821268 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,07344845 0,09815896 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,07344845 0,09810529 ! microtubule-based transport GO:0010970 59 22 0,000 0,07344845 0,09805168 ! hindlimb morphogenesis GO:0035137 47 22 0,000 0,07344845 0,09799813 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,07344845 0,09794464 ! inactivation of MAPK activity GO:0000188 45 22 0,000 0,07344845 0,0978912 ! vacuolar transport GO:0007034 41 22 0,000 0,07344845 0,09783783 ! central nervous system neuron development GO:0021954 47 22 0,000 0,07344845 0,09778451 ! fucose metabolic process GO:0006004 44 22 0,000 0,07344845 0,09773125 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,07344845 0,09767805 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,07344845 0,0976249 ! apoptotic nuclear changes GO:0030262 34 22 0,000 0,07344845 0,09757182 ! stem cell differentiation GO:0048863 57 22 0,000 0,07344845 0,09751879 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,07344845 0,09746582 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 0,07344845 0,09741291 ! cytolysis GO:0019835 27 22 0,000 0,07344845 0,09736005 ! renal system process GO:0003014 42 22 0,000 0,07344845 0,09730725 ! vasodilation GO:0042311 40 22 0,000 0,07344845 0,09725451 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,07344845 0,09720183 ! G1 phase GO:0051318 44 22 0,000 0,07344845 0,0971492 ! detection of chemical stimulus GO:0009593 42 22 0,000 0,07344845 0,09709663 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,07344845 0,09704412 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,07344845 0,09699166 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,07344845 0,09693926 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,07344845 0,09688692 ! sarcomere organization GO:0045214 32 22 0,000 0,07344845 0,09683463 ! positive regulation of B cell activation GO:0050871 42 22 0,000 0,07344845 0,0967824 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,07344845 0,09673023 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,07344845 0,09667811 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,07344845 0,09662605 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,07344845 0,09657404 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,07344845 0,09652209 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 0,000 0,07344845 0,0964702 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,07344845 0,09641836 ! protein stabilization GO:0050821 41 22 0,000 0,07344845 0,09636658 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,07665677 0,100522 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,07665677 0,10046808 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,07665677 0,10041421 ! glycerol metabolic process GO:0006071 40 23 0,000 0,07665677 0,10036039 ! viral genome replication GO:0019079 44 23 0,000 0,07665677 0,10030664 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,07665677 0,10025294 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,07665677 0,1001993 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,07665677 0,10014572 ! regeneration GO:0031099 42 23 0,000 0,07665677 0,10009219 ! axis specification GO:0009798 43 23 0,000 0,07665677 0,10003872 ! visual behavior GO:0007632 46 23 0,000 0,07665677 0,09998531 ! regulation of DNA recombination GO:0000018 51 23 0,000 0,07665677 0,09993196 ! response to ethanol GO:0045471 47 23 0,000 0,07665677 0,09987866 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,07665677 0,09982542 ! activation of pro-apoptotic gene products GO:0008633 51 23 0,000 0,07665677 0,09977224 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,07665677 0,09971911 ! peroxisome organization GO:0007031 43 23 0,000 0,07665677 0,09966604 ! lysosome organization GO:0007040 47 23 0,000 0,07665677 0,09961303 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 0,07665677 0,09956007 ! vesicle targeting GO:0006903 49 23 0,000 0,07665677 0,09950717 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,07665677 0,09945432 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,07665677 0,09940154 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,07665677 0,0993488 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,07665677 0,09929613 ! DNA modification GO:0006304 36 23 0,000 0,07665677 0,0992435 ! fatty acid transport GO:0015908 47 23 0,000 0,07665677 0,09919094 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,07665677 0,09913843 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,07665677 0,09908597 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,07665677 0,09903358 ! hormone transport GO:0009914 41 23 0,000 0,07665677 0,09898123 ! cell-cell recognition GO:0009988 28 23 0,000 0,07665677 0,09892894 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,07665677 0,09887671 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,07665677 0,09882453 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,07665677 0,09877241 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,07985407 0,1028379 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,07985407 0,10278371 GO:0016444|somatic cell DNA recombination, ! DNA catabolic process, endonucleolytic GO:0000737 38 24 0,000 0,07985407 0,10272959 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,07985407 0,10267552 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,07985407 0,10262151 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,07985407 0,10256756 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 0,07985407 0,10251366 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,07985407 0,10245982 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,07985407 0,10240603 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,07985407 0,1023523 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,07985407 0,10229863 GO:0042278|purine nucleoside metabolic process, ! positive regulation of cytoskeleton organization GO:0051495 52 24 0,000 0,07985407 0,10224502 ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,07985407 0,10219146 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,07985407 0,10213795 GO:0051693|actin filament capping, ! regulation of viral reproduction GO:0050792 41 24 0,000 0,07985407 0,10208451 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,07985407 0,10203111 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 52 24 0,000 0,07985407 0,10197778 ! leukotriene metabolic process GO:0006691 47 24 0,000 0,07985407 0,1019245 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,07985407 0,10187127 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,07985407 0,10181811 ! membrane depolarization GO:0051899 45 24 0,000 0,07985407 0,10176499 ! pallium development GO:0021543 56 24 0,000 0,07985407 0,10171193 ! oogenesis GO:0048477 44 24 0,000 0,07985407 0,10165893 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,07985407 0,10160598 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,07985407 0,10155309 ! platelet activation GO:0030168 41 24 0,000 0,07985407 0,10150026 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,07985407 0,10144747 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,07985407 0,10139475 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,07985407 0,10134207 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,07985407 0,10128946 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,07985407 0,10123689 ! negative regulation of catabolic process GO:0009895 52 24 0,000 0,07985407 0,10118438 ! regulation of amine transport GO:0051952 41 24 0,000 0,07985407 0,10113193 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 0,000 0,07985407 0,10107953 ! positive regulation of fibroblast proliferation GO:0048146 48 25 0,000 0,08304039 0,10505834 ! myeloid leukocyte differentiation GO:0002573 46 25 0,000 0,08304039 0,10500397 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 0,000 0,08304039 0,10494964 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,08304039 0,10489538 ! leukocyte adhesion GO:0007159 55 25 0,000 0,08304039 0,10484117 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,08304039 0,10478702 ! phototransduction GO:0007602 37 25 0,000 0,08304039 0,10473292 ! keratinization GO:0031424 37 25 0,000 0,08304039 0,10467888 ! vacuole organization GO:0007033 49 25 0,000 0,08304039 0,10462489 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,08304039 0,10457096 ! receptor metabolic process GO:0043112 53 25 0,000 0,08304039 0,10451708 ! chromosome condensation GO:0030261 48 25 0,000 0,08304039 0,10446327 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,08304039 0,1044095 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,08304039 0,10435579 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,08304039 0,10430214 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,08304039 0,10424854 ! immunoglobulin production GO:0002377 62 25 0,000 0,08304039 0,104195 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,08304039 0,10414151 ! leukocyte homeostasis GO:0001776 50 25 0,000 0,08304039 0,10408808 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,08304039 0,1040347 ! liver development GO:0001889 55 25 0,000 0,08304039 0,10398137 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,08621576 0,1079022 ! initiation of viral infection GO:0019059 60 26 0,000 0,08621576 0,10784695 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,08621576 0,10779176 ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,08621576 0,10773662 ! regulation of transcription factor import into nucleus GO:0042990 58 26 0,000 0,08621576 0,10768154 ! microtubule organizing center organization GO:0031023 42 26 0,000 0,08621576 0,10762652 GO:0051297|centrosome organization, ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,08621576 0,10757155 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,08621576 0,10751664 ! digestive system process GO:0022600 49 26 0,000 0,08621576 0,10746178 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,08621576 0,10740698 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 0,000 0,08621576 0,10735224 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 51 26 0,000 0,08621576 0,10729755 ! neural crest cell development GO:0014032 59 26 0,000 0,08621576 0,10724292 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,08621576 0,10718834 ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,08621576 0,10713382 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,08621576 0,10707936 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,08621576 0,10702495 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,08621576 0,10697059 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,08621576 0,10691629 ! regulation of blood coagulation GO:0030193 46 26 0,000 0,08621576 0,10686205 ! positive regulation of nuclear division GO:0051785 41 26 0,000 0,08621576 0,10680786 GO:0045840|positive regulation of mitosis, ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,08621576 0,10675372 ! blastocyst development GO:0001824 50 26 0,000 0,08621576 0,10669964 ! telomere organization GO:0032200 46 26 0,000 0,08621576 0,10664562 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,08621576 0,10659165 ! neural tube closure GO:0001843 58 26 0,000 0,08621576 0,10653773 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 44 26 0,000 0,08621576 0,10648387 ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,08621576 0,10643006 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,08621576 0,10637631 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,08938022 0,11022508 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,08938022 0,11016947 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,08938022 0,11011391 ! positive regulation of cell projection organization GO:0031346 66 27 0,000 0,08938022 0,11005841 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,08938022 0,11000296 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,08938022 0,10994757 ! iron ion transport GO:0006826 65 27 0,000 0,08938022 0,10989224 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,08938022 0,10983696 ! superoxide metabolic process GO:0006801 41 27 0,000 0,08938022 0,10978174 ! tube lumen formation GO:0035148 59 27 0,000 0,08938022 0,10972657 ! response to toxin GO:0009636 49 27 0,000 0,08938022 0,10967146 ! cellular response to oxidative stress GO:0034599 43 27 0,000 0,08938022 0,10961641 ! regulation of chromosome organization GO:0033044 49 27 0,000 0,08938022 0,10956141 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,08938022 0,10950646 ! leukocyte proliferation GO:0070661 59 27 0,000 0,08938022 0,10945157 GO:0032943|mononuclear cell proliferation, ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,09253382 0,11325657 ! vesicle docking GO:0048278 55 28 0,000 0,09253382 0,11319986 ! circadian rhythm GO:0007623 56 28 0,000 0,09253382 0,1131432 ! dendrite development GO:0016358 67 28 0,000 0,09253382 0,1130866 ! negative regulation of protein modification process GO:0031400 66 28 0,000 0,09253382 0,11303006 ! fat cell differentiation GO:0045444 57 28 0,000 0,09253382 0,11297357 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,09253382 0,11291714 ! sperm motility GO:0030317 37 28 0,000 0,09253382 0,11286077 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,09253382 0,11280445 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,09253382 0,11274819 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,09253382 0,11269198 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,09253382 0,11263583 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,09253382 0,11257974 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,09253382 0,1125237 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,09253382 0,11246772 ! glutathione metabolic process GO:0006749 42 28 0,000 0,09253382 0,11241179 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,09253382 0,11235592 ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,09253382 0,11230011 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,09253382 0,11224435 ! translational initiation GO:0006413 66 29 0,000 0,09567658 0,11599895 ! cellular iron ion homeostasis GO:0006879 57 29 0,000 0,09567658 0,11594141 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,09567658 0,11588393 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,09567658 0,1158265 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! autophagy GO:0006914 47 29 0,000 0,09567658 0,11576913 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,09567658 0,11571182 ! primary neural tube formation GO:0014020 61 29 0,000 0,09567658 0,11565457 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,09567658 0,11559737 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,09567658 0,11554023 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,09567658 0,11548314 ! somitogenesis GO:0001756 52 29 0,000 0,09567658 0,11542611 ! synaptogenesis GO:0007416 46 29 0,000 0,09567658 0,11536914 ! negative regulation of neuron differentiation GO:0045665 46 29 0,000 0,09567658 0,11531223 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,09567658 0,11525537 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,09567658 0,11519856 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,09567658 0,11514181 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,09880855 0,11885243 ! phenol metabolic process GO:0018958 56 30 0,000 0,09880855 0,11879394 ! negative regulation of protein complex assembly GO:0031333 68 30 0,000 0,09880855 0,1187355 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,09880855 0,11867713 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,09880855 0,11861881 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,09880855 0,11856055 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,09880855 0,11850234 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,09880855 0,1184442 ! acute-phase response GO:0006953 50 30 0,000 0,09880855 0,11838611 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,09880855 0,11832808 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,09880855 0,1182701 ! myofibril assembly GO:0030239 50 30 0,000 0,09880855 0,11821218 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 72 30 0,000 0,09880855 0,11815432 ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,09880855 0,11809651 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,09880855 0,11803877 ! cell fate determination GO:0001709 64 30 0,000 0,09880855 0,11798107 ! positive regulation of multicellular organism growth GO:0040018 55 30 0,000 0,09880855 0,11792344 ! phospholipid transport GO:0015914 65 30 0,000 0,09880855 0,11786586 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,09880855 0,11780833 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,09880855 0,11775087 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,09880855 0,11769346 ! negative regulation of transcription regulator activity GO:0090048 57 30 0,000 0,09880855 0,1176361 GO:0043433|negative regulation of transcription factor activity, ! regulation of B cell activation GO:0050864 55 30 0,000 0,09880855 0,1175788 ! regulation of coagulation GO:0050818 52 30 0,000 0,09880855 0,11752156 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,10192975 0,12117488 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,10192975 0,12111595 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,10192975 0,12105707 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,10192975 0,12099824 ! cell junction assembly GO:0034329 85 31 0,000 0,10192975 0,12093948 ! regulation of innate immune response GO:0045088 57 31 0,000 0,10192975 0,12088077 ! peptide transport GO:0015833 60 31 0,000 0,10192975 0,12082212 ! male gonad development GO:0008584 56 31 0,000 0,10192975 0,12076352 ! iron ion homeostasis GO:0055072 60 31 0,000 0,10192975 0,12070499 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,10192975 0,1206465 ! detection of light stimulus GO:0009583 44 31 0,000 0,10192975 0,12058808 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 0,000 0,10192975 0,12052971 ! natural killer cell activation GO:0030101 50 31 0,000 0,10192975 0,1204714 ! cofactor catabolic process GO:0051187 54 31 0,000 0,10192975 0,12041315 ! response to heat GO:0009408 54 31 0,000 0,10192975 0,12035495 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,10192975 0,1202968 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,10504024 0,12390792 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,10504024 0,12384812 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,10504024 0,12378837 ! spindle organization GO:0007051 50 32 0,000 0,10504024 0,12372869 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,10504024 0,12366906 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,10504024 0,12360949 ! muscle cell development GO:0055001 52 32 0,000 0,10504024 0,12354998 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,10504024 0,12349052 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,10504024 0,12343112 ! gene silencing GO:0016458 71 32 0,000 0,10504024 0,12337178 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,10814004 0,12695152 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,10814004 0,12689054 GO:0055092|sterol homeostasis, ! pigment biosynthetic process GO:0046148 73 33 0,000 0,10814004 0,12682962 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,10814004 0,12676877 ! triglyceride metabolic process GO:0006641 46 33 0,000 0,10814004 0,12670797 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,10814004 0,12664722 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,10814004 0,12658654 ! leukocyte chemotaxis GO:0030595 55 33 0,000 0,10814004 0,12652591 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,10814004 0,12646535 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,10814004 0,12640484 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,10814004 0,12634438 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,11122918 0,12989144 ! glial cell differentiation GO:0010001 67 34 0,000 0,11122918 0,12982938 ! post-embryonic development GO:0009791 76 34 0,000 0,11122918 0,12976738 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,11122918 0,12970544 ! cholesterol transport GO:0030301 62 34 0,000 0,11122918 0,12964356 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,11122918 0,12958174 ! spliceosome assembly GO:0000245 75 34 0,000 0,11122918 0,12951997 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,11122918 0,12945827 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,11122918 0,12939662 ! negative regulation of MAP kinase activity GO:0043407 78 34 0,000 0,11122918 0,12933503 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,11122918 0,1292735 ! adult locomotory behavior GO:0008344 62 34 0,000 0,11122918 0,12921203 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,11430772 0,13272517 ! negative regulation of secretion GO:0051048 68 35 0,000 0,11430772 0,13266212 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,11430772 0,13259913 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,11430772 0,13253619 ! membrane docking GO:0022406 69 35 0,000 0,11430772 0,13247332 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,11430772 0,13241051 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,11430772 0,13234775 ! regulation of striated muscle tissue development GO:0016202 81 35 0,000 0,11430772 0,13228506 ! ceramide metabolic process GO:0006672 72 35 0,000 0,11430772 0,13222243 ! sterol transport GO:0015918 63 35 0,000 0,11430772 0,13215985 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,11430772 0,13209733 ! placenta development GO:0001890 53 35 0,000 0,11430772 0,13203488 ! vesicle localization GO:0051648 70 35 0,000 0,11430772 0,13197248 ! regulation of muscle development GO:0048634 82 36 0,000 0,11737568 0,13545054 ! mitotic sister chromatid segregation GO:0000070 63 36 0,000 0,11737568 0,13538658 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,11737568 0,13532269 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,11737568 0,13525886 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,11737568 0,13519509 ! negative regulation of DNA binding GO:0043392 67 36 0,000 0,11737568 0,13513138 ! positive regulation of cell development GO:0010720 85 36 0,000 0,11737568 0,13506773 ! protein targeting to membrane GO:0006612 75 36 0,000 0,11737568 0,13500414 ! regulation of proteolysis GO:0030162 77 36 0,000 0,11737568 0,1349406 ! aerobic respiration GO:0009060 56 36 0,000 0,11737568 0,13487713 ! cytokine production GO:0001816 68 36 0,000 0,11737568 0,13481372 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,11737568 0,13475037 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 0,000 0,1204331 0,13819542 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,1204331 0,13813054 ! sister chromatid segregation GO:0000819 65 37 0,000 0,1204331 0,13806572 ! actomyosin structure organization GO:0031032 68 37 0,000 0,1204331 0,13800096 ! cell junction organization GO:0034330 96 37 0,000 0,1204331 0,13793627 ! maintenance of protein location in cell GO:0032507 89 37 0,000 0,1204331 0,13787163 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,1204331 0,13780705 ! androgen receptor signaling pathway GO:0030521 81 37 0,000 0,1204331 0,13774254 ! regulation of microtubule-based process GO:0032886 86 37 0,000 0,1204331 0,13767808 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,12348001 0,14109526 ! meiosis I GO:0007127 74 38 0,000 0,12348001 0,1410293 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,12348001 0,14096339 ! organic anion transport GO:0015711 82 38 0,000 0,12348001 0,14089755 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,12348001 0,14083178 ! neutral lipid metabolic process GO:0006638 54 38 0,000 0,12348001 0,14076606 GO:0006639|acylglycerol metabolic process, ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,12348001 0,1407004 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,12348001 0,14063481 ! regulation of protein stability GO:0031647 77 38 0,000 0,12348001 0,14056928 ! spermatid development GO:0007286 69 38 0,000 0,12348001 0,1405038 ! pigment metabolic process GO:0042440 87 38 0,000 0,12348001 0,14043839 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,12651645 0,14382489 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,12651645 0,143758 ! negative regulation of binding GO:0051100 71 39 0,000 0,12651645 0,14369117 ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,12651645 0,14362439 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,12651645 0,14355769 ! erythrocyte homeostasis GO:0034101 75 39 0,000 0,12651645 0,14349104 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,12651645 0,14342445 ! positive regulation of leukocyte proliferation GO:0070665 70 39 0,000 0,12651645 0,14335793 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,12651645 0,14329147 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,12954246 0,14665071 GO:0006956|complement activation, ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,12954246 0,14658279 ! learning GO:0007612 82 40 0,000 0,12954246 0,14651492 ! lipid homeostasis GO:0055088 75 40 0,000 0,12954246 0,14644713 ! mismatch repair GO:0006298 58 40 0,000 0,12954246 0,14637939 ! glycerol ether metabolic process GO:0006662 57 40 0,000 0,12954246 0,14631171 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,12954246 0,1462441 ! RNA export from nucleus GO:0006405 61 41 0,000 0,13255807 0,14957939 ! mRNA catabolic process GO:0006402 79 41 0,000 0,13255807 0,14951033 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,13255807 0,14944134 ! regulation of hormone secretion GO:0046883 69 41 0,000 0,13255807 0,14937241 ! establishment or maintenance of cell polarity GO:0007163 96 41 0,000 0,13255807 0,14930354 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,13255807 0,14923474 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,13255807 0,149166 ! feeding behavior GO:0007631 69 41 0,000 0,13255807 0,14909732 ! mesenchymal cell development GO:0014031 94 41 0,000 0,13255807 0,14902871 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,13255807 0,14896016 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 95 41 0,000 0,13255807 0,14889167 ! spermatid differentiation GO:0048515 73 41 0,000 0,13255807 0,14882324 ! RNA modification GO:0009451 64 41 0,000 0,13255807 0,14875488 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,13556332 0,15205748 ! ear morphogenesis GO:0042471 64 42 0,000 0,13556332 0,1519877 ! organic ether metabolic process GO:0018904 59 42 0,000 0,13556332 0,15191798 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,13556332 0,15184833 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,13556332 0,15177874 ! regulation of protein secretion GO:0050708 77 42 0,000 0,13556332 0,15170921 ! cytokinesis GO:0000910 84 42 0,000 0,13556332 0,15163974 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,13556332 0,15157034 ! positive regulation of transcription factor activity GO:0051091 71 43 0,000 0,13855825 0,15484803 GO:0090047|positive regulation of transcription regulator activity, ! epithelial cell differentiation GO:0030855 83 43 0,000 0,13855825 0,15477723 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,13855825 0,15470649 ! regulation of tube size GO:0035150 76 43 0,000 0,13855825 0,15463581 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,13855825 0,1545652 ! glucose transport GO:0015758 66 43 0,000 0,13855825 0,15449466 ! striated muscle cell differentiation GO:0051146 91 43 0,000 0,13855825 0,15442418 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,13855825 0,15435376 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,13855825 0,15428341 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,13855825 0,15421312 ! segmentation GO:0035282 78 43 0,000 0,13855825 0,15414289 ! ion transmembrane transport GO:0034220 79 43 0,000 0,13855825 0,15407273 ! neuron migration GO:0001764 85 43 0,000 0,13855825 0,15400264 ! regulation of myeloid cell differentiation GO:0045637 105 43 0,000 0,13855825 0,1539326 ! response to reactive oxygen species GO:0000302 75 44 0,000 0,14154288 0,15717693 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,14154288 0,15710552 ! negative regulation of protein complex disassembly GO:0043242 113 44 0,000 0,14154288 0,15703417 ! hexose transport GO:0008645 68 44 0,000 0,14154288 0,15696289 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 0,000 0,14154288 0,15689167 ! striated muscle contraction GO:0006941 85 44 0,000 0,14154288 0,15682052 ! phagocytosis GO:0006909 105 44 0,000 0,14154288 0,15674943 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,14154288 0,15667841 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,14451725 0,15989839 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,14451725 0,159826 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! keratinocyte differentiation GO:0030216 81 45 0,000 0,14451725 0,15975368 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,14451725 0,15968143 ! female gamete generation GO:0007292 71 45 0,000 0,14451725 0,15960924 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,14451725 0,15953712 ! polyol metabolic process GO:0019751 77 45 0,000 0,14451725 0,15946506 ! maintenance of location in cell GO:0051651 101 45 0,000 0,14451725 0,15939306 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,1474814 0,16258892 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,1474814 0,16251559 ! glycolysis GO:0006096 71 46 0,000 0,1474814 0,16244232 ! leukocyte migration GO:0050900 75 46 0,000 0,1474814 0,16236911 ! negative regulation of cell migration GO:0030336 122 46 0,000 0,1474814 0,16229597 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,1474814 0,1622229 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,1474814 0,16214989 ! pigmentation GO:0043473 103 46 0,000 0,1474814 0,16207695 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,15043536 0,16524892 ! positive regulation of defense response GO:0031349 88 48 0,000 0,15337917 0,16840688 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,15337917 0,16833123 ! regulation of JAK-STAT cascade GO:0046425 76 48 0,000 0,15337917 0,16825564 ! cellular component disassembly GO:0022411 89 48 0,000 0,15337917 0,16818012 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 0,000 0,15337917 0,16810467 ! positive regulation of DNA binding GO:0043388 83 48 0,000 0,15337917 0,16802929 ! male sex differentiation GO:0046661 93 48 0,000 0,15337917 0,16795398 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,15337917 0,16787873 ! regulation of inflammatory response GO:0050727 84 48 0,000 0,15337917 0,16780355 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,15337917 0,16772843 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,15337917 0,16765339 ! response to calcium ion GO:0051592 94 49 0,000 0,15631287 0,17078369 ! detection of stimulus involved in sensory perception GO:0050906 75 49 0,000 0,15631287 0,17070734 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,15631287 0,17063107 ! JNK cascade GO:0007254 106 49 0,000 0,15631287 0,17055486 ! protein homooligomerization GO:0051260 84 49 0,000 0,15631287 0,17047872 ! regulation of ion transport GO:0043269 86 50 0,000 0,15923647 0,17358978 ! endocrine system development GO:0035270 109 50 0,000 0,15923647 0,17351236 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,15923647 0,173435 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,15923647 0,17335771 GO:0019724|B cell mediated immunity, ! regulation of gene expression, epigenetic GO:0040029 116 50 0,000 0,15923647 0,17328049 ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,15923647 0,17320334 ! epidermal cell differentiation GO:0009913 87 50 0,000 0,15923647 0,17312626 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,15923647 0,17304925 ! regulation of cell projection organization GO:0031344 135 51 0,000 0,16215004 0,17613719 ! viral infectious cycle GO:0019058 104 51 0,000 0,16215004 0,1760589 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,16215004 0,17598069 ! peptide metabolic process GO:0006518 80 51 0,000 0,16215004 0,17590255 ! response to temperature stimulus GO:0009266 84 51 0,000 0,16215004 0,17582447 ! detection of abiotic stimulus GO:0009582 80 51 0,000 0,16215004 0,17574647 ! positive regulation of binding GO:0051099 88 52 0,000 0,16505358 0,17881415 ! Notch signaling pathway GO:0007219 111 52 0,000 0,16505358 0,17873488 ! regulation of protein complex disassembly GO:0043244 127 52 0,000 0,16505358 0,17865569 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,16505358 0,17857657 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,16505358 0,17849752 ! excretion GO:0007588 87 52 0,000 0,16505358 0,17841854 ! DNA-dependent DNA replication GO:0006261 82 52 0,000 0,16505358 0,17833963 ! histone modification GO:0016570 104 52 0,000 0,16505358 0,17826079 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,16505358 0,17818201 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,16505358 0,17810331 ! amino acid activation GO:0043038 98 52 0,000 0,16505358 0,17802468 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,16794715 0,1810657 ! inner ear development GO:0048839 89 53 0,000 0,16794715 0,18098583 ! chromatin remodeling GO:0006338 122 53 0,000 0,16794715 0,18090603 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,16794715 0,1808263 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,16794715 0,18074664 ! vesicle organization GO:0016050 127 53 0,000 0,16794715 0,18066705 ! cartilage development GO:0051216 99 53 0,000 0,16794715 0,18058753 ! regulation of translational initiation GO:0006446 87 54 0,000 0,17083076 0,18360737 ! neuromuscular process GO:0050905 107 54 0,000 0,17083076 0,18352663 ! regulation of muscle contraction GO:0006937 94 54 0,000 0,17083076 0,18344596 ! membrane fusion GO:0006944 122 54 0,000 0,17083076 0,18336536 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,17083076 0,18328483 ! covalent chromatin modification GO:0016569 115 54 0,000 0,17083076 0,18320437 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,17083076 0,18312398 ! RNA catabolic process GO:0006401 103 55 0,000 0,17370447 0,18612282 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,17370447 0,18604122 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,17370447 0,18595969 ! cell recognition GO:0008037 98 55 0,000 0,17370447 0,18587824 ! cell maturation GO:0048469 107 55 0,000 0,17370447 0,18579686 ! regulation of protein polymerization GO:0032271 117 55 0,000 0,17370447 0,18571554 ! negative regulation of cell motion GO:0051271 142 55 0,000 0,17370447 0,1856343 ! negative regulation of cytoskeleton organization GO:0051494 139 56 0,000 0,1765683 0,18861231 ! glucose catabolic process GO:0006007 88 56 0,000 0,1765683 0,18852987 ! RNA elongation GO:0006354 90 56 0,000 0,1765683 0,18844751 ! chloride transport GO:0006821 102 57 0,000 0,17942228 0,19140988 ! regulation of actin filament length GO:0030832 118 58 0,000 0,18226645 0,1943592 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,18226645 0,1942744 ! positive regulation of organelle organization GO:0010638 108 58 0,000 0,18226645 0,19418968 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,18226645 0,19410503 ! maintenance of location GO:0051235 124 58 0,000 0,18226645 0,19402045 ! nuclear export GO:0051168 110 59 0,000 0,18510084 0,19695181 ! establishment of organelle localization GO:0051656 122 59 0,000 0,18510084 0,19686607 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,18792549 0,19978327 ! DNA catabolic process GO:0006308 94 60 0,000 0,18792549 0,19969637 ! regulation of endocytosis GO:0030100 104 60 0,000 0,18792549 0,19960955 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,18792549 0,1995228 ! adult behavior GO:0030534 104 60 0,000 0,18792549 0,19943613 ! positive regulation of secretion GO:0051047 110 61 0,000 0,19074042 0,20233558 ! regulation of cellular component size GO:0032535 125 61 0,000 0,19074042 0,20224777 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,19074042 0,20216002 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,19074042 0,20207236 ! cytokine-mediated signaling pathway GO:0019221 112 61 0,000 0,19074042 0,20198476 ! regulation of heart contraction GO:0008016 123 61 0,000 0,19074042 0,20189725 ! proton transport GO:0015992 117 61 0,000 0,19074042 0,20180981 ! negative regulation of response to stimulus GO:0048585 106 61 0,000 0,19074042 0,20172245 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,19354568 0,20460065 ! tRNA processing GO:0008033 102 62 0,000 0,19354568 0,20451215 ! regulation of protein complex assembly GO:0043254 132 63 0,000 0,19634129 0,20737647 ! regulation of mitosis GO:0007088 112 63 0,000 0,19634129 0,20728685 GO:0051783|regulation of nuclear division, ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,19634129 0,20719731 ! hydrogen transport GO:0006818 121 64 0,000 0,19912729 0,21004662 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,19912729 0,20995596 ! integrin-mediated signaling pathway GO:0007229 160 64 0,000 0,19912729 0,20986539 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,20190371 0,21269977 ! lymphocyte mediated immunity GO:0002449 122 65 0,000 0,20190371 0,21260809 ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,20190371 0,21251648 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,20190371 0,21242496 ! ear development GO:0043583 114 66 0,000 0,20467058 0,21524332 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,20467058 0,2151507 ! regulation of lipid metabolic process GO:0019216 132 66 0,000 0,20467058 0,21505816 ! steroid hormone receptor signaling pathway GO:0030518 146 66 0,000 0,20467058 0,2149657 ! chromosome segregation GO:0007059 127 67 0,000 0,20742794 0,21776814 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,20742794 0,21767459 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,20742794 0,21758113 ! secondary metabolic process GO:0019748 125 67 0,000 0,20742794 0,21748775 ! myeloid cell differentiation GO:0030099 126 67 0,000 0,20742794 0,21739444 ! regulation of cellular response to stress GO:0080135 142 68 0,000 0,21017581 0,22017989 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,21017581 0,22008552 ! hexose catabolic process GO:0019320 113 68 0,000 0,21017581 0,21999122 ! extracellular matrix organization GO:0030198 146 68 0,000 0,21017581 0,21989701 ! negative regulation of ligase activity GO:0051352 116 68 0,000 0,21017581 0,21980287 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! detection of external stimulus GO:0009581 102 68 0,000 0,21017581 0,21970882 ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,21017581 0,21961485 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 0,000 0,21017581 0,21952095 ! cell projection assembly GO:0030031 138 68 0,000 0,21017581 0,21942714 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,21291424 0,22219115 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 0,000 0,21291424 0,22209628 ! homeostasis of number of cells GO:0048872 131 69 0,000 0,21291424 0,22200149 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,21291424 0,22190678 ! single fertilization GO:0007338 83 69 0,000 0,21291424 0,22181215 ! cell redox homeostasis GO:0045454 114 70 0,000 0,21564325 0,22455944 ! germ cell development GO:0007281 133 70 0,000 0,21564325 0,22446376 ! activation of immune response GO:0002253 120 70 0,000 0,21564325 0,22436816 ! protein maturation by peptide bond cleavage GO:0051605 118 70 0,000 0,21564325 0,22427265 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,21836287 0,22700446 ! cAMP-mediated signaling GO:0019933 124 71 0,000 0,21836287 0,22690791 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 0,000 0,21836287 0,22681143 ! carbohydrate transport GO:0008643 114 72 0,000 0,22107314 0,22952897 ! actin filament organization GO:0007015 167 72 0,000 0,22107314 0,22943147 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 0,000 0,22107314 0,22933404 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 0,000 0,22107314 0,2292367 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,22107314 0,22913945 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,22107314 0,22904227 ! humoral immune response GO:0006959 115 73 0,000 0,22377408 0,2317423 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,22377408 0,2316441 ! regulation of immune effector process GO:0002697 156 73 0,000 0,22377408 0,23154599 ! acute inflammatory response GO:0002526 118 74 0,000 0,22646574 0,23423192 ! amino acid transport GO:0006865 148 74 0,000 0,22646574 0,2341328 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 0,000 0,22646574 0,23403376 ! organelle localization GO:0051640 155 74 0,000 0,22646574 0,2339348 ! regulation of transcription factor activity GO:0051090 137 75 0,000 0,22914814 0,23660562 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 143 75 0,000 0,22914814 0,23650566 ! leukocyte mediated immunity GO:0002443 136 75 0,000 0,22914814 0,23640579 ! cell-matrix adhesion GO:0007160 181 76 0,000 0,23182131 0,23906267 ! regulation of actin cytoskeleton organization GO:0032956 167 76 0,000 0,23182131 0,2389618 ! learning or memory GO:0007611 161 76 0,000 0,23182131 0,23886102 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,23182131 0,23876032 ! regulation of blood pressure GO:0008217 134 76 0,000 0,23182131 0,2386597 ! amine catabolic process GO:0009310 136 77 0,000 0,23448529 0,24130058 ! neurotransmitter transport GO:0006836 142 77 0,000 0,23448529 0,24119898 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,23448529 0,24109746 ! positive regulation of ligase activity GO:0051351 130 77 0,000 0,23448529 0,24099603 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,23448529 0,24089469 ! antigen processing and presentation GO:0019882 117 78 0,000 0,23714011 0,24351966 ! fertilization GO:0009566 99 78 0,000 0,23714011 0,24341735 ! positive regulation of lymphocyte activation GO:0051251 142 78 0,000 0,23714011 0,24331511 ! blood coagulation GO:0007596 151 79 0,000 0,23978579 0,2459264 GO:0050817|coagulation, ! regulation of actin filament-based process GO:0032970 170 79 0,000 0,23978579 0,2458232 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 0,000 0,23978579 0,24572009 ! steroid biosynthetic process GO:0006694 146 79 0,000 0,23978579 0,24561706 ! regulation of synaptic transmission GO:0050804 159 79 0,000 0,23978579 0,24551412 ! activation of protein kinase activity GO:0032147 170 80 0,000 0,24242237 0,2481097 ! negative regulation of organelle organization GO:0010639 181 80 0,000 0,24242237 0,2480058 ! meiosis GO:0007126 143 81 0,000 0,24504988 0,25058889 GO:0051327|M phase of meiotic cell cycle, ! muscle cell differentiation GO:0042692 178 81 0,000 0,24504988 0,25048404 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 0,000 0,24504988 0,25037928 ! cell-substrate adhesion GO:0031589 189 82 0,000 0,24766835 0,25294891 ! meiotic cell cycle GO:0051321 144 82 0,000 0,24766835 0,2528432 ! regulation of adenylate cyclase activity GO:0045761 165 83 0,000 0,25027782 0,25540046 ! exocytosis GO:0006887 153 83 0,000 0,25027782 0,25529382 ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,25027782 0,25518727 ! inorganic anion transport GO:0015698 156 83 0,000 0,25027782 0,25508081 ! response to metal ion GO:0010038 158 84 0,000 0,2528783 0,25762372 ! response to nutrient GO:0007584 135 84 0,000 0,2528783 0,25751634 ! digestion GO:0007586 130 84 0,000 0,2528783 0,25740904 ! regulation of ligase activity GO:0051340 147 84 0,000 0,2528783 0,25730183 ! hemostasis GO:0007599 165 85 0,000 0,25546984 0,25983048 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,25546984 0,25972236 ! regulation of cyclase activity GO:0031279 168 85 0,000 0,25546984 0,25961432 ! regulation of transmission of nerve impulse GO:0051969 167 85 0,000 0,25546984 0,25950637 ! regulation of cAMP biosynthetic process GO:0030817 173 86 0,000 0,25805246 0,26202085 ! regulation of lyase activity GO:0051339 169 86 0,000 0,25805246 0,26191199 ! positive regulation of cell activation GO:0050867 161 86 0,000 0,25805246 0,26180323 GO:0002696|positive regulation of leukocyte activation, ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,2606262 0,26430461 ! alcohol catabolic process GO:0046164 142 87 0,000 0,2606262 0,26419494 ! nucleosome assembly GO:0006334 126 87 0,000 0,2606262 0,26408536 ! cellular respiration GO:0045333 143 88 0,000 0,26319108 0,26657372 ! amine biosynthetic process GO:0009309 146 88 0,000 0,26319108 0,26646325 ! sensory perception of smell GO:0007608 117 88 0,000 0,26319108 0,26635286 ! chromatin assembly GO:0031497 128 88 0,000 0,26319108 0,26624257 ! regulation of DNA binding GO:0051101 167 89 0,000 0,26574714 0,26871699 ! cellular defense response GO:0006968 123 89 0,000 0,26574714 0,26860581 ! regulation of neurological system process GO:0031644 175 89 0,000 0,26574714 0,26849473 ! response to inorganic substance GO:0010035 173 90 0,000 0,2682944 0,27095627 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,2682944 0,2708443 ! positive regulation of protein modification process GO:0031401 156 90 0,000 0,2682944 0,27073243 ! response to unfolded protein GO:0006986 139 90 0,000 0,2682944 0,27062065 ! regulation of cell cycle process GO:0010564 161 90 0,000 0,2682944 0,27050896 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 0,000 0,27083289 0,27295576 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! defense response to bacterium GO:0042742 112 91 0,000 0,27083289 0,2728432 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,27336265 0,27527822 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 0,000 0,2758837 0,27770247 GO:0010498|proteasomal protein catabolic process, ! amine transport GO:0015837 181 93 0,000 0,2758837 0,27758809 ! vitamin metabolic process GO:0006766 153 93 0,000 0,2758837 0,27747381 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,27839608 0,27988544 ! female pregnancy GO:0007565 166 94 0,000 0,27839608 0,27977031 ! sterol metabolic process GO:0016125 166 94 0,000 0,27839608 0,27965527 ! regulation of defense response GO:0031347 171 95 0,000 0,28089981 0,28205435 ! nucleosome organization GO:0034728 143 95 0,000 0,28089981 0,28193847 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,28089981 0,28182269 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,28089981 0,281707 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,28089981 0,2815914 ! response to protein stimulus GO:0051789 158 96 0,000 0,28339493 0,28397613 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,28588146 0,28635031 ! transcription initiation GO:0006352 171 97 0,000 0,28588146 0,28623295 ! mRNA transport GO:0051028 185 100 0,000 0,29328981 0,29353011 ! positive regulation of immune response GO:0050778 175 100 0,000 0,29328981 0,29340991 ! hormone metabolic process GO:0042445 171 100 0,000 0,29328981 0,29328981