pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6666-Schmidt-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! release of cytochrome c from mitochondria GO:0001836 23 14 3,000 5,262E-07 1,21E-03 ! apoptotic mitochondrial changes GO:0008637 29 18 3,000 1,585E-06 1,822E-03 ! ER overload response GO:0006983 7 6 2,000 2,274E-06 1,744E-03 ! regulation of bone mineralization GO:0030500 29 21 3,000 3,065E-06 1,762E-03 ! regulation of biomineral formation GO:0070167 31 23 3,000 4,5E-06 2,07E-03 ! regulation of bone remodeling GO:0046850 90 53 4,000 6,105E-06 2,34E-03 ! regulation of gliogenesis GO:0014013 20 8 2,000 6,323E-06 2,078E-03 GO:0045685|regulation of glial cell differentiation, ! phosphoinositide 3-kinase cascade GO:0014065 23 8 2,000 6,323E-06 1,818E-03 ! regulation of tissue remodeling GO:0034103 91 54 4,000 6,702E-06 1,713E-03 ! lung alveolus development GO:0048286 17 9 2,000 9,451E-06 2,174E-03 ! lung development GO:0030324 94 59 4,000 1,041E-05 2,176E-03 ! respiratory tube development GO:0030323 99 62 4,000 1,33E-05 2,548E-03 ! peptide or protein amino-terminal blocking GO:0018409 14 10 2,000 1,345E-05 2,38E-03 ! respiratory system development GO:0060541 100 64 4,000 1,555E-05 2,554E-03 ! regulation of caspase activity GO:0043281 97 65 4,000 1,678E-05 2,572E-03 ! regulation of endopeptidase activity GO:0052548 99 67 4,000 1,947E-05 2,798E-03 ! cartilage condensation GO:0001502 18 12 2,000 2,449E-05 3,313E-03 ! regulation of intracellular protein transport GO:0033157 59 35 3,000 2,544E-05 3,251E-03 ! regulation of peptidase activity GO:0052547 106 72 4,000 2,766E-05 3,349E-03 ! N-terminal protein amino acid modification GO:0031365 18 13 2,000 3,172E-05 3,648E-03 ! positive regulation of bone mineralization GO:0030501 19 13 2,000 3,172E-05 3,474E-03 ! cellular response to starvation GO:0009267 21 14 2,000 4,023E-05 4,206E-03 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 2,000 4,023E-05 4,023E-03 GO:0060675|ureteric bud morphogenesis, ! positive regulation of biomineral formation GO:0070169 20 14 2,000 4,023E-05 3,856E-03 ! induction of apoptosis by intracellular signals GO:0008629 67 40 3,000 4,358E-05 4,009E-03 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 3,000 5,298E-05 4,686E-03 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 3,000 5,819E-05 4,957E-03 ! epithelial tube morphogenesis GO:0060562 65 43 3,000 5,819E-05 4,78E-03 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 2,000 7,436E-05 5,898E-03 ! regulation of ossification GO:0030278 71 46 3,000 7,609E-05 5,833E-03 ! cellular response to nutrient levels GO:0031669 27 18 2,000 8,892E-05 6,597E-03 ! regulation of intracellular transport GO:0032386 78 49 3,000 9,769E-05 7,021E-03 ! cartilage development GO:0051216 70 49 3,000 9,769E-05 6,808E-03 ! positive regulation of ossification GO:0045778 30 19 2,000 1,052E-04 7,117E-03 ! response to starvation GO:0042594 30 19 2,000 1,052E-04 6,914E-03 ! positive regulation of intracellular transport GO:0032388 29 19 2,000 1,052E-04 6,722E-03 ! positive regulation of osteoblast differentiation GO:0045669 33 20 2,000 1,233E-04 7,667E-03 ! skeletal system morphogenesis GO:0048705 78 53 3,000 1,33E-04 8,05E-03 ! positive regulation of bone remodeling GO:0046852 33 21 2,000 1,434E-04 8,456E-03 GO:0034105|positive regulation of tissue remodeling, ! protein amino acid acylation GO:0043543 37 21 2,000 1,434E-04 8,245E-03 ! response to endoplasmic reticulum stress GO:0034976 25 21 2,000 1,434E-04 8,044E-03 ! cellular response to extracellular stimulus GO:0031668 32 21 2,000 1,434E-04 7,852E-03 ! ureteric bud development GO:0001657 32 22 2,000 1,654E-04 8,849E-03 ! negative regulation of protein kinase activity GO:0006469 99 57 3,000 1,768E-04 9,239E-03 ! negative regulation of kinase activity GO:0033673 100 58 3,000 1,891E-04 9,667E-03 ! regulation of transcription factor import into nucleus GO:0042990 46 23 2,000 1,896E-04 9,479E-03 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 2,000 1,896E-04 9,277E-03 ! ER-nuclear signaling pathway GO:0006984 27 23 2,000 1,896E-04 9,084E-03 ! negative regulation of cell development GO:0010721 56 24 2,000 2,159E-04 0,01013362 GO:0050768|negative regulation of neurogenesis, ! regulation of osteoblast differentiation GO:0045667 37 24 2,000 2,159E-04 9,931E-03 ! negative regulation of transferase activity GO:0051348 105 61 3,000 2,3E-04 0,01037465 ! negative regulation of bone resorption GO:0045779 10 5 1,000 2,369E-04 0,01047865 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 1,000 2,369E-04 0,01028094 ! negative regulation of survival gene product expression GO:0008634 6 5 1,000 2,369E-04 0,01009055 ! melanosome organization GO:0032438 7 5 1,000 2,369E-04 9,907E-03 ! negative regulation of gliogenesis GO:0014014 16 5 1,000 2,369E-04 9,73E-03 GO:0045686|negative regulation of glial cell differentiation, ! apical protein localization GO:0045176 6 5 1,000 2,369E-04 9,559E-03 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 1,000 2,369E-04 9,395E-03 ! regulation of chromosome organization GO:0033044 35 25 2,000 2,445E-04 9,53E-03 ! BMP signaling pathway GO:0030509 40 28 2,000 3,445E-04 0,01320603 ! regulation of helicase activity GO:0051095 11 6 1,000 3,542E-04 0,01335605 ! regulation of protein export from nucleus GO:0046825 6 6 1,000 3,542E-04 0,01314063 ! N-terminal protein amino acid acetylation GO:0006474 7 6 1,000 3,542E-04 0,01293205 ! mRNA stabilization GO:0048255 15 6 1,000 3,542E-04 0,01272998 GO:0043489|RNA stabilization, ! protein lipoylation GO:0009249 10 6 1,000 3,542E-04 0,01253414 ! pigment granule organization GO:0048753 11 6 1,000 3,542E-04 0,01234423 ! activation of caspase activity by cytochrome c GO:0008635 10 6 1,000 3,542E-04 0,01215998 ! cerebral cortex neuron differentiation GO:0021895 12 6 1,000 3,542E-04 0,01198116 ! enucleate erythrocyte differentiation GO:0043353 9 6 1,000 3,542E-04 0,01180752 ! establishment of melanosome localization GO:0032401 9 6 1,000 3,542E-04 0,01163884 ! negative regulation of neuroblast proliferation GO:0007406 18 6 1,000 3,542E-04 0,01147492 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 1,000 3,542E-04 0,01131554 ! regulation of protein import into nucleus GO:0042306 53 29 2,000 3,829E-04 0,01206378 ! tube morphogenesis GO:0035239 118 73 3,000 4,588E-04 0,01425955 ! mitochondrion organization GO:0007005 104 73 3,000 4,588E-04 0,01406942 ! metanephros development GO:0001656 58 31 2,000 4,677E-04 0,01415373 ! response to mechanical stimulus GO:0009612 43 31 2,000 4,677E-04 0,01396992 ! regulation of lipid kinase activity GO:0043550 12 7 1,000 4,943E-04 0,01457638 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 1,000 4,943E-04 0,01439187 ! T-helper 1 type immune response GO:0042088 11 7 1,000 4,943E-04 0,01421197 ! protein-cofactor linkage GO:0018065 13 7 1,000 4,943E-04 0,01403651 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 1,000 4,943E-04 0,01386534 ! asymmetric protein localization GO:0008105 8 7 1,000 4,943E-04 0,01369829 ! G1 DNA damage checkpoint GO:0031571 18 7 1,000 4,943E-04 0,01353521 ! B cell lineage commitment GO:0002326 17 7 1,000 4,943E-04 0,01337597 ! melanosome localization GO:0032400 10 7 1,000 4,943E-04 0,01322044 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 1,000 4,943E-04 0,01306848 ! T cell lineage commitment GO:0002360 12 7 1,000 4,943E-04 0,01291997 ! response to tumor cell GO:0002347 12 7 1,000 4,943E-04 0,01277481 ! neuroblast proliferation GO:0007405 13 7 1,000 4,943E-04 0,01263286 ! establishment of pigment granule localization GO:0051905 13 7 1,000 4,943E-04 0,01249404 ! regulation of protein transport GO:0051223 114 76 3,000 5,348E-04 0,01336926 GO:0070201|regulation of establishment of protein localization, ! negative regulation of hydrolase activity GO:0051346 50 33 2,000 5,637E-04 0,01394006 ! neuron migration GO:0001764 46 34 2,000 6,16E-04 0,0150729 ! induction of positive chemotaxis GO:0050930 14 8 1,000 6,57E-04 0,01590627 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 1,000 6,57E-04 0,01574058 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 1,000 6,57E-04 0,01557831 ! keratinocyte proliferation GO:0043616 12 8 1,000 6,57E-04 0,01541934 ! middle ear morphogenesis GO:0042474 9 8 1,000 6,57E-04 0,01526359 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 1,000 6,57E-04 0,01511096 ! positive regulation of endothelial cell migration GO:0010595 18 8 1,000 6,57E-04 0,01496134 ! regulation of vascular permeability GO:0043114 12 8 1,000 6,57E-04 0,01481466 ! lens development in camera-type eye GO:0002088 10 8 1,000 6,57E-04 0,01467083 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 1,000 6,57E-04 0,01452977 ! pigment granule localization GO:0051875 14 8 1,000 6,57E-04 0,01439139 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 1,000 6,57E-04 0,01425562 ! regulation of macrophage differentiation GO:0045649 14 8 1,000 6,57E-04 0,01412239 ! regulation of telomere maintenance GO:0032204 10 8 1,000 6,57E-04 0,01399163 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 1,000 6,57E-04 0,01386326 ! keratinocyte differentiation GO:0030216 47 35 2,000 6,714E-04 0,01403815 ! ossification GO:0001503 134 82 3,000 7,129E-04 0,01477218 GO:0060348|bone development, ! regulation of protein localization GO:0032880 132 85 3,000 8,161E-04 0,01675982 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 1,000 8,42E-04 0,01713829 ! negative regulation of striated muscle development GO:0045843 11 9 1,000 8,42E-04 0,01698795 ! motor axon guidance GO:0008045 14 9 1,000 8,42E-04 0,01684023 ! negative regulation of BMP signaling pathway GO:0030514 13 9 1,000 8,42E-04 0,01669506 ! cell cycle arrest GO:0007050 150 86 3,000 8,528E-04 0,01676364 ! interphase of mitotic cell cycle GO:0051329 156 86 3,000 8,528E-04 0,01662158 ! pigmentation GO:0043473 74 38 2,000 8,562E-04 0,01654872 ! interphase GO:0051325 159 88 3,000 9,295E-04 0,01781487 ! regulation of neurogenesis GO:0050767 153 89 3,000 9,696E-04 0,0184303 ! epidermal cell differentiation GO:0009913 53 40 2,000 9,957E-04 0,01877131 ! positive regulation of protein transport GO:0051222 55 40 2,000 9,957E-04 0,0186187 ! negative regulation of muscle development GO:0048635 12 10 1,000 1,049E-03 0,01946006 ! negative regulation of blood pressure GO:0045776 22 10 1,000 1,049E-03 0,01930438 ! hippocampus development GO:0021766 19 10 1,000 1,049E-03 0,01915117 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 1,000 1,049E-03 0,01900037 ! blood vessel remodeling GO:0001974 21 10 1,000 1,049E-03 0,01885193 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 1,000 1,049E-03 0,01870579 ! response to X-ray GO:0010165 16 10 1,000 1,049E-03 0,0185619 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 1,000 1,049E-03 0,01842021 ! regulation of bone resorption GO:0045124 24 10 1,000 1,049E-03 0,01828066 ! positive regulation of leukocyte migration GO:0002687 23 10 1,000 1,049E-03 0,01814321 ! cardiac cell differentiation GO:0035051 16 10 1,000 1,049E-03 0,01800782 ! T cell receptor signaling pathway GO:0050852 18 10 1,000 1,049E-03 0,01787443 ! cytoplasmic sequestering of protein GO:0051220 14 10 1,000 1,049E-03 0,017743 ! peptidyl-amino acid modification GO:0018193 147 93 3,000 1,142E-03 0,01917763 ! branching morphogenesis of a tube GO:0048754 72 42 2,000 1,149E-03 0,01914627 ! regulation of gene-specific transcription GO:0032583 69 43 2,000 1,231E-03 0,02036196 ! activation of caspase activity GO:0006919 65 43 2,000 1,231E-03 0,02021651 ! cortical cytoskeleton organization GO:0030865 20 11 1,000 1,278E-03 0,02085006 ! regulation of positive chemotaxis GO:0050926 17 11 1,000 1,278E-03 0,02070323 GO:0050927|positive regulation of positive chemotaxis, ! detection of mechanical stimulus GO:0050982 15 11 1,000 1,278E-03 0,02055845 ! positive regulation of endothelial cell proliferation GO:0001938 18 11 1,000 1,278E-03 0,02041569 ! regulation of intracellular pH GO:0051453 17 11 1,000 1,278E-03 0,02027489 ! regulation of leukocyte migration GO:0002685 24 11 1,000 1,278E-03 0,02013602 ! negative regulation of mast cell proliferation GO:0070667 17 11 1,000 1,278E-03 0,01999904 GO:0042130|negative regulation of T cell proliferation, ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 1,000 1,529E-03 0,02376058 ! positive regulation of cell growth GO:0030307 16 12 1,000 1,529E-03 0,02360111 ! histone acetylation GO:0016573 23 12 1,000 1,529E-03 0,02344377 ! peptidyl-lysine modification GO:0018205 18 12 1,000 1,529E-03 0,02328851 ! response to gamma radiation GO:0010332 20 12 1,000 1,529E-03 0,0231353 ! regulation of mRNA stability GO:0043488 27 12 1,000 1,529E-03 0,02298409 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 1,000 1,529E-03 0,02283484 ! positive regulation of caspase activity GO:0043280 72 48 2,000 1,694E-03 0,02514288 GO:0010952|positive regulation of peptidase activity, ! regulation of angiogenesis GO:0045765 94 49 2,000 1,799E-03 0,02651702 ! morphogenesis of a branching structure GO:0001763 86 49 2,000 1,799E-03 0,02634812 ! lipid localization GO:0010876 24 13 1,000 1,801E-03 0,02621946 GO:0019915|lipid storage, ! negative regulation of protein import into nucleus GO:0042308 25 13 1,000 1,801E-03 0,02605456 ! positive regulation of protein import into nucleus GO:0042307 23 13 1,000 1,801E-03 0,02589172 ! regulation of cellular pH GO:0030641 20 13 1,000 1,801E-03 0,0257309 ! cellular pigmentation GO:0033059 24 13 1,000 1,801E-03 0,02557207 ! regulation of RNA stability GO:0043487 28 13 1,000 1,801E-03 0,02541518 ! ear development GO:0043583 72 50 2,000 1,907E-03 0,02673882 ! phosphoinositide phosphorylation GO:0046854 21 14 1,000 2,095E-03 0,02919817 ! negative regulation of bone remodeling GO:0046851 26 14 1,000 2,095E-03 0,02902228 ! limbic system development GO:0021761 25 14 1,000 2,095E-03 0,02884849 ! negative regulation of caspase activity GO:0043154 20 14 1,000 2,095E-03 0,02867678 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 1,000 2,095E-03 0,02850709 ! G1/S transition checkpoint GO:0031575 33 14 1,000 2,095E-03 0,0283394 ! epithelial to mesenchymal transition GO:0001837 22 14 1,000 2,095E-03 0,02817367 ! establishment of organelle localization GO:0051656 85 52 2,000 2,135E-03 0,02854461 ! kidney development GO:0001822 90 53 2,000 2,255E-03 0,02997629 ! positive regulation of cell size GO:0045793 20 15 1,000 2,409E-03 0,03184569 ! negative regulation of cell cycle process GO:0010948 24 15 1,000 2,409E-03 0,03166372 ! skin development GO:0043588 25 15 1,000 2,409E-03 0,03148381 ! embryonic forelimb morphogenesis GO:0035115 17 15 1,000 2,409E-03 0,03130594 ! lipid phosphorylation GO:0046834 23 15 1,000 2,409E-03 0,03113006 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 1,000 2,409E-03 0,03095615 ! regulation of survival gene product expression GO:0045884 20 15 1,000 2,409E-03 0,03078417 ! peptidyl-serine phosphorylation GO:0018105 23 15 1,000 2,409E-03 0,03061409 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 1,000 2,409E-03 0,03044588 ! negative regulation of tissue remodeling GO:0034104 27 15 1,000 2,409E-03 0,03027951 ! regulation of BMP signaling pathway GO:0030510 21 15 1,000 2,409E-03 0,03011495 ! negative regulation of leukocyte proliferation GO:0070664 25 15 1,000 2,409E-03 0,02995217 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 29 15 1,000 2,409E-03 0,02979113 ! mesoderm development GO:0007498 76 55 2,000 2,507E-03 0,03083881 ! DNA damage response, signal transduction GO:0042770 96 56 2,000 2,64E-03 0,03229684 ! protein amino acid acetylation GO:0006473 28 16 1,000 2,745E-03 0,03339974 ! fructose metabolic process GO:0006000 20 16 1,000 2,745E-03 0,03322395 ! G1 phase GO:0051318 27 16 1,000 2,745E-03 0,03305001 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 1,000 2,745E-03 0,03287787 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 1,000 2,745E-03 0,03270752 ! forelimb morphogenesis GO:0035136 19 17 1,000 3,101E-03 0,0367599 ! negative regulation of peptidase activity GO:0010466 23 17 1,000 3,101E-03 0,03657139 ! inactivation of MAPK activity GO:0000188 27 17 1,000 3,101E-03 0,0363848 ! actin filament bundle formation GO:0051017 26 17 1,000 3,101E-03 0,03620011 ! neuromuscular junction development GO:0007528 23 17 1,000 3,101E-03 0,03601728 ! long-chain fatty acid transport GO:0015909 24 17 1,000 3,101E-03 0,03583628 ! negative regulation of intracellular transport GO:0032387 29 17 1,000 3,101E-03 0,0356571 ! peptidyl-serine modification GO:0018209 27 17 1,000 3,101E-03 0,03547971 ! cell-cell junction organization GO:0045216 25 17 1,000 3,101E-03 0,03530406 ! proximal/distal pattern formation GO:0009954 25 17 1,000 3,101E-03 0,03513015 ! negative regulation of homeostatic process GO:0032845 28 17 1,000 3,101E-03 0,03495794 ! embryonic limb morphogenesis GO:0030326 86 60 2,000 3,213E-03 0,03605125 GO:0035113|embryonic appendage morphogenesis, ! regulation of homeostatic process GO:0032844 105 60 2,000 3,213E-03 0,03587624 ! urogenital system development GO:0001655 101 61 2,000 3,368E-03 0,03741742 ! axis specification GO:0009798 26 18 1,000 3,477E-03 0,03844849 ! response to retinoic acid GO:0032526 25 18 1,000 3,477E-03 0,03826452 ! peptide cross-linking GO:0018149 31 18 1,000 3,477E-03 0,03808231 ! somitogenesis GO:0001756 24 18 1,000 3,477E-03 0,03790183 ! negative regulation of neuron differentiation GO:0045665 24 18 1,000 3,477E-03 0,03772304 ! activation of JUN kinase activity GO:0007257 23 18 1,000 3,477E-03 0,03754594 ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 1,000 3,477E-03 0,03737049 ! negative regulation of T cell activation GO:0050868 25 18 1,000 3,477E-03 0,03719667 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 1,000 3,477E-03 0,03702447 ! negative regulation of cell growth GO:0030308 106 62 2,000 3,526E-03 0,03737598 ! organelle localization GO:0051640 96 62 2,000 3,526E-03 0,03720453 ! cell cycle checkpoint GO:0000075 108 64 2,000 3,857E-03 0,04051218 ! negative regulation of cell size GO:0045792 108 64 2,000 3,857E-03 0,04032803 ! appendage morphogenesis GO:0035107 93 64 2,000 3,857E-03 0,04014555 GO:0035108|limb morphogenesis, ! neuropeptide signaling pathway GO:0007218 79 64 2,000 3,857E-03 0,03996472 ! adaptive immune response GO:0002250 94 64 2,000 3,857E-03 0,0397855 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! response to alkaloid GO:0043279 32 19 1,000 3,874E-03 0,03977533 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 1,000 3,874E-03 0,03959855 ! response to vitamin A GO:0033189 26 19 1,000 3,874E-03 0,03942333 ! cell structure disassembly during apoptosis GO:0006921 24 19 1,000 3,874E-03 0,03924966 ! apoptotic nuclear changes GO:0030262 24 19 1,000 3,874E-03 0,03907751 ! plasma membrane fusion GO:0045026 23 19 1,000 3,874E-03 0,03890687 ! regulation of endothelial cell migration GO:0010594 40 19 1,000 3,874E-03 0,03873771 ! cytolysis GO:0019835 20 19 1,000 3,874E-03 0,03857001 ! negative regulation of angiogenesis GO:0016525 36 19 1,000 3,874E-03 0,03840376 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 1,000 3,874E-03 0,03823894 ! appendage development GO:0048736 94 65 2,000 4,03E-03 0,03961001 GO:0060173|limb development, ! activation of immune response GO:0002253 83 65 2,000 4,03E-03 0,03944146 ! protein oligomerization GO:0051259 100 65 2,000 4,03E-03 0,03927434 ! response to vitamin GO:0033273 29 20 1,000 4,29E-03 0,04163762 ! hindlimb morphogenesis GO:0035137 32 20 1,000 4,29E-03 0,04146267 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 1,000 4,29E-03 0,04128919 ! pallium development GO:0021543 38 20 1,000 4,29E-03 0,04111715 ! positive regulation of locomotion GO:0040017 35 20 1,000 4,29E-03 0,04094654 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! camera-type eye morphogenesis GO:0048593 34 20 1,000 4,29E-03 0,04077734 ! DNA catabolic process, endonucleolytic GO:0000737 26 21 1,000 4,727E-03 0,04474136 ! regulation of chemotaxis GO:0050920 36 21 1,000 4,727E-03 0,044558 ! dendrite development GO:0016358 35 21 1,000 4,727E-03 0,04437613 ! activation of pro-apoptotic gene products GO:0008633 36 21 1,000 4,727E-03 0,04419574 ! cell aging GO:0007569 32 21 1,000 4,727E-03 0,04401681 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 1,000 4,727E-03 0,04383932 ! regulation of vasoconstriction GO:0019229 31 21 1,000 4,727E-03 0,04366326 ! fatty acid transport GO:0015908 30 21 1,000 4,727E-03 0,0434886 ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 1,000 4,727E-03 0,04331534 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 2,000 4,962E-03 0,04528919 ! protein import into nucleus, translocation GO:0000060 36 22 1,000 5,183E-03 0,04711983 ! regulation of fibroblast proliferation GO:0048145 35 22 1,000 5,183E-03 0,04693432 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 1,000 5,183E-03 0,04675026 ! vasculogenesis GO:0001570 33 22 1,000 5,183E-03 0,04656764 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 1,000 5,183E-03 0,04638644 ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 1,000 5,183E-03 0,04620665 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of behavior GO:0050795 38 22 1,000 5,183E-03 0,04602825 ! neural tube closure GO:0001843 33 22 1,000 5,183E-03 0,04585122 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! positive regulation of JUN kinase activity GO:0043507 28 22 1,000 5,183E-03 0,04567554 ! protein tetramerization GO:0051262 39 22 1,000 5,183E-03 0,04550121 ! response to hypoxia GO:0001666 132 72 2,000 5,368E-03 0,04694781 ! negative regulation of organelle organization GO:0010639 115 72 2,000 5,368E-03 0,04676997 ! positive regulation of cell adhesion GO:0045785 37 23 1,000 5,659E-03 0,04911379 ! myelination GO:0042552 35 23 1,000 5,659E-03 0,04892915 ! cellular iron ion homeostasis GO:0006879 37 23 1,000 5,659E-03 0,04874589 ! negative regulation of DNA replication GO:0008156 35 23 1,000 5,659E-03 0,048564 ! response to oxygen levels GO:0070482 137 74 2,000 5,794E-03 0,04954061 ! cellular response to hormone stimulus GO:0032870 109 74 2,000 5,794E-03 0,04935713 ! negative regulation of growth GO:0045926 123 75 2,000 6,014E-03 0,05104413 ! response to nutrient GO:0007584 104 75 2,000 6,014E-03 0,05085647 ! insulin receptor signaling pathway GO:0008286 40 24 1,000 6,154E-03 0,05184325 ! regulation of endothelial cell proliferation GO:0001936 46 24 1,000 6,154E-03 0,05165404 ! mitochondrial membrane organization GO:0007006 39 24 1,000 6,154E-03 0,05146621 ! primary neural tube formation GO:0014020 35 24 1,000 6,154E-03 0,05127974 ! base-excision repair GO:0006284 31 24 1,000 6,154E-03 0,05109461 ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 1,000 6,154E-03 0,05091082 ! regulation of JUN kinase activity GO:0043506 34 24 1,000 6,154E-03 0,05072835 ! regulation of DNA binding GO:0051101 119 77 2,000 6,47E-03 0,05314387 ! negative regulation of actin filament depolymerization GO:0030835 36 25 1,000 6,667E-03 0,05457306 ! iron ion homeostasis GO:0055072 39 25 1,000 6,667E-03 0,05437954 ! positive regulation of nuclear division GO:0051785 39 25 1,000 6,667E-03 0,05418739 GO:0045840|positive regulation of mitosis, ! negative regulation of lymphocyte activation GO:0051250 37 25 1,000 6,667E-03 0,05399658 ! forebrain development GO:0030900 131 80 2,000 7,19E-03 0,05802757 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 1,000 7,2E-03 0,0579027 ! regulation of pH GO:0006885 36 26 1,000 7,2E-03 0,05770094 ! regulation of actin filament depolymerization GO:0030834 39 27 1,000 7,751E-03 0,06190342 ! response to ionizing radiation GO:0010212 47 27 1,000 7,751E-03 0,06168922 ! negative regulation of leukocyte activation GO:0002695 39 27 1,000 7,751E-03 0,0614765 ! negative regulation of protein transport GO:0051224 49 27 1,000 7,751E-03 0,06126524 ! complement activation, classical pathway GO:0006958 36 28 1,000 8,321E-03 0,06554327 ! erythrocyte differentiation GO:0030218 38 28 1,000 8,321E-03 0,06531957 ! immune response-activating signal transduction GO:0002757 38 28 1,000 8,321E-03 0,06509739 GO:0002764|immune response-regulating signal transduction, ! regulation of systemic arterial blood pressure GO:0003073 47 28 1,000 8,321E-03 0,06487673 ! mesoderm formation GO:0001707 46 28 1,000 8,321E-03 0,06465755 ! negative regulation of MAP kinase activity GO:0043407 54 28 1,000 8,321E-03 0,06443985 ! ensheathment of neurons GO:0007272 43 28 1,000 8,321E-03 0,0642236 GO:0008366|axon ensheathment, ! neural tube formation GO:0001841 41 28 1,000 8,321E-03 0,06400881 ! regulation of DNA metabolic process GO:0051052 135 85 2,000 8,494E-03 0,06511771 ! rRNA metabolic process GO:0016072 107 85 2,000 8,494E-03 0,06490137 GO:0006364|rRNA processing, ! positive regulation of MAP kinase activity GO:0043406 121 85 2,000 8,494E-03 0,06468647 ! anterior/posterior pattern formation GO:0009952 124 85 2,000 8,494E-03 0,06447298 ! negative regulation of multicellular organismal process GO:0051241 133 85 2,000 8,494E-03 0,0642609 ! formation of primary germ layer GO:0001704 48 29 1,000 8,909E-03 0,06718386 ! telencephalon development GO:0021537 52 29 1,000 8,909E-03 0,0669643 ! eye morphogenesis GO:0048592 51 29 1,000 8,909E-03 0,06674618 ! skeletal muscle tissue development GO:0007519 123 87 2,000 9,051E-03 0,06759007 GO:0060538|skeletal muscle organ development, ! protein processing GO:0016485 114 88 2,000 9,338E-03 0,06950497 ! spindle organization GO:0007051 37 30 1,000 9,515E-03 0,07059703 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 1,000 9,515E-03 0,07037003 ! positive regulation of neurogenesis GO:0050769 45 30 1,000 9,515E-03 0,07014449 ! embryonic epithelial tube formation GO:0001838 44 30 1,000 9,515E-03 0,06992038 ! negative regulation of cell activation GO:0050866 44 30 1,000 9,515E-03 0,06969771 ! establishment of vesicle localization GO:0051650 45 30 1,000 9,515E-03 0,06947644 ! DNA damage checkpoint GO:0000077 53 31 1,000 0,01013922 0,07379813 ! mammary gland development GO:0030879 57 31 1,000 0,01013922 0,07356533 ! odontogenesis GO:0042476 50 31 1,000 0,01013922 0,07333399 ! maintenance of protein location in cell GO:0032507 60 31 1,000 0,01013922 0,07310411 ! segmentation GO:0035282 41 31 1,000 0,01013922 0,07287566 ! regulation of striated muscle tissue development GO:0016202 47 31 1,000 0,01013922 0,07264863 ! mesoderm morphogenesis GO:0048332 49 31 1,000 0,01013922 0,07242301 ! positive regulation of gene-specific transcription GO:0043193 47 31 1,000 0,01013922 0,07219879 ! cell fate commitment GO:0045165 141 92 2,000 0,01053729 0,07480175 ! positive regulation of immune response GO:0050778 121 92 2,000 0,01053729 0,07457159 ! regulation of muscle development GO:0048634 48 32 1,000 0,01078089 0,07606147 ! mitotic sister chromatid segregation GO:0000070 45 32 1,000 0,01078089 0,07582887 ! negative regulation of DNA metabolic process GO:0051053 48 32 1,000 0,01078089 0,07559768 ! meiosis I GO:0007127 52 32 1,000 0,01078089 0,0753679 ! monovalent inorganic cation homeostasis GO:0055067 45 32 1,000 0,01078089 0,07513952 ! peripheral nervous system development GO:0007422 53 32 1,000 0,01078089 0,07491251 ! vesicle localization GO:0051648 47 32 1,000 0,01078089 0,07468687 ! sister chromatid segregation GO:0000819 46 33 1,000 0,01144006 0,07901545 ! ear morphogenesis GO:0042471 42 33 1,000 0,01144006 0,07877888 ! cell junction organization GO:0034330 63 33 1,000 0,01144006 0,07854372 ! nucleus organization GO:0006997 49 33 1,000 0,01144006 0,07830995 ! negative regulation of DNA binding GO:0043392 54 33 1,000 0,01144006 0,07807758 ! positive regulation of cell development GO:0010720 54 33 1,000 0,01144006 0,07784658 ! androgen receptor signaling pathway GO:0030521 54 33 1,000 0,01144006 0,07761695 ! cytokinesis GO:0000910 52 33 1,000 0,01144006 0,07738866 ! regulation of binding GO:0051098 151 95 2,000 0,01149287 0,07751788 ! angiogenesis GO:0001525 149 95 2,000 0,01149287 0,07729122 ! protein maturation GO:0051604 129 96 2,000 0,01182215 0,07927386 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 1,000 0,01211657 0,08101192 ! feeding behavior GO:0007631 45 34 1,000 0,01211657 0,0807771 ! mitotic cell cycle checkpoint GO:0007093 63 34 1,000 0,01211657 0,08054364 ! DNA integrity checkpoint GO:0031570 57 34 1,000 0,01211657 0,08031153 ! erythrocyte homeostasis GO:0034101 45 34 1,000 0,01211657 0,08008075 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 1,000 0,01211657 0,07985129 ! dorsal/ventral pattern formation GO:0009953 44 34 1,000 0,01211657 0,07962314 ! cellular response to insulin stimulus GO:0032869 52 34 1,000 0,01211657 0,0793963 ! regulation of action potential in neuron GO:0019228 54 35 1,000 0,01281021 0,08370309 ! maintenance of protein location GO:0045185 65 35 1,000 0,01281021 0,08346597 ! glycogen metabolic process GO:0005977 48 35 1,000 0,01281021 0,08323019 ! protein homooligomerization GO:0051260 52 35 1,000 0,01281021 0,08299574 ! homophilic cell adhesion GO:0007156 149 100 2,000 0,0131934 0,08523824 ! positive regulation of transcription factor activity GO:0051091 49 36 1,000 0,01352082 0,08710894 GO:0090047|positive regulation of transcription regulator activity, ! negative regulation of binding GO:0051100 58 36 1,000 0,01352082 0,08686562 ! tissue remodeling GO:0048771 62 36 1,000 0,01352082 0,08662366 ! neural tube development GO:0021915 50 36 1,000 0,01352082 0,08638304 ! hormone-mediated signaling GO:0009755 49 36 1,000 0,01352082 0,08614375 ! glucan metabolic process GO:0044042 49 36 1,000 0,01352082 0,08590578 GO:0006073|cellular glucan metabolic process, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 1,000 0,01424822 0,09027796 GO:0006956|complement activation, ! learning GO:0007612 67 37 1,000 0,01424822 0,09002994 ! striated muscle cell differentiation GO:0051146 54 38 1,000 0,01499222 0,09447151 ! monocarboxylic acid transport GO:0015718 62 38 1,000 0,01499222 0,09421339 ! regulation of T cell proliferation GO:0042129 58 38 1,000 0,01499222 0,09395668 ! mesenchymal cell development GO:0014031 64 38 1,000 0,01499222 0,09370136 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! maintenance of location in cell GO:0051651 69 38 1,000 0,01499222 0,09344743 ! negative regulation of protein complex disassembly GO:0043242 67 39 1,000 0,01575265 0,09792185 ! morphogenesis of embryonic epithelium GO:0016331 60 39 1,000 0,01575265 0,09765791 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 1,000 0,01575265 0,09739539 ! regulation of epithelial cell proliferation GO:0050678 71 39 1,000 0,01575265 0,09713428 ! JNK cascade GO:0007254 54 39 1,000 0,01575265 0,09687456 ! synapse organization GO:0050808 55 39 1,000 0,01575265 0,09661623 ! response to calcium ion GO:0051592 58 40 1,000 0,01652933 0,10111025 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 1,000 0,01652933 0,10084205 ! positive regulation of response to external stimulus GO:0032103 65 40 1,000 0,01652933 0,10057527 ! detection of stimulus involved in sensory perception GO:0050906 50 40 1,000 0,01652933 0,1003099 ! T cell differentiation GO:0030217 65 40 1,000 0,01652933 0,10004593 ! double-strand break repair GO:0006302 67 40 1,000 0,01652933 0,09978334 ! B cell differentiation GO:0030183 62 40 1,000 0,01652933 0,09952213 ! regulation of myeloid cell differentiation GO:0045637 69 40 1,000 0,01652933 0,09926228 ! protein amino acid lipidation GO:0006497 62 41 1,000 0,01732209 0,10375209 ! energy reserve metabolic process GO:0006112 59 41 1,000 0,01732209 0,1034826 ! positive regulation of DNA binding GO:0043388 57 41 1,000 0,01732209 0,10321451 ! regulation of T cell differentiation GO:0045580 59 41 1,000 0,01732209 0,10294781 ! regulation of JNK cascade GO:0046328 58 41 1,000 0,01732209 0,10268248 ! mitochondrial transport GO:0006839 60 42 1,000 0,01813075 0,10719983 ! cellular component disassembly GO:0022411 64 42 1,000 0,01813075 0,10692496 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 1,000 0,01813075 0,10665149 ! regulation of cell shape GO:0008360 78 42 1,000 0,01813075 0,10637942 ! positive regulation of binding GO:0051099 59 43 1,000 0,01895515 0,11093346 ! vesicle organization GO:0016050 79 43 1,000 0,01895515 0,11065191 ! response to insulin stimulus GO:0032868 63 43 1,000 0,01895515 0,11037177 ! regulation of action potential GO:0001508 71 44 1,000 0,01979511 0,11497163 ! negative regulation of cell migration GO:0030336 92 44 1,000 0,01979511 0,11468203 ! detection of abiotic stimulus GO:0009582 58 44 1,000 0,01979511 0,11439388 ! regulation of mast cell proliferation GO:0070666 64 44 1,000 0,01979511 0,11410718 ! positive regulation of cell cycle GO:0045787 77 45 1,000 0,02065047 0,11874021 ! lipoprotein biosynthetic process GO:0042158 67 45 1,000 0,02065047 0,1184441 ! vascular process in circulatory system GO:0003018 69 45 1,000 0,02065047 0,11814946 ! protein amino acid autophosphorylation GO:0046777 80 45 1,000 0,02065047 0,11785629 ! regulation of protein complex disassembly GO:0043244 77 46 1,000 0,02152105 0,12252084 ! histone modification GO:0016570 68 46 1,000 0,02152105 0,12221832 ! response to UV GO:0009411 75 46 1,000 0,02152105 0,12191729 ! covalent chromatin modification GO:0016569 75 47 1,000 0,02240669 0,12662259 ! negative regulation of immune system process GO:0002683 73 47 1,000 0,02240669 0,12631224 ! regulation of leukocyte proliferation GO:0070663 71 47 1,000 0,02240669 0,12600341 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of neuron apoptosis GO:0043523 77 47 1,000 0,02240669 0,12569608 ! cellular polysaccharide metabolic process GO:0044264 63 48 1,000 0,02330723 0,13042974 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 1,000 0,02330723 0,13011316 ! gastrulation GO:0007369 73 48 1,000 0,02330723 0,12979812 ! heart morphogenesis GO:0003007 65 48 1,000 0,02330723 0,1294846 ! regulation of DNA replication GO:0006275 75 48 1,000 0,02330723 0,12917258 ! immunoglobulin mediated immune response GO:0016064 66 48 1,000 0,02330723 0,12886207 GO:0019724|B cell mediated immunity, ! nuclear export GO:0051168 69 48 1,000 0,02330723 0,12855305 ! regulation of lymphocyte differentiation GO:0045619 69 48 1,000 0,02330723 0,12824551 ! integrin-mediated signaling pathway GO:0007229 81 49 1,000 0,02422249 0,13296355 ! maintenance of location GO:0051235 84 49 1,000 0,02422249 0,13264697 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 0,02435868 0,1330759 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 0,02435868 0,13276055 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 0,02435868 0,1324467 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 0,02435868 0,13213432 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 0,02435868 0,13182342 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02435868 0,13151398 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 0,02435868 0,13120598 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 0,02435868 0,13089942 ! sleep GO:0030431 11 5 0,000 0,02435868 0,1305943 ! nucleotide-sugar transport GO:0015780 8 5 0,000 0,02435868 0,13029059 ! regulation of interferon-beta production GO:0032648 5 5 0,000 0,02435868 0,12998829 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 0,02435868 0,12968739 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 0,02435868 0,12938788 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 0,02435868 0,12908975 ! tongue development GO:0043586 6 5 0,000 0,02435868 0,128793 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 0,02435868 0,1284976 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,02435868 0,12820356 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 0,02435868 0,12791085 ! cobalt ion transport GO:0006824 9 5 0,000 0,02435868 0,12761948 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 0,02435868 0,12732944 ! SMAD protein complex assembly GO:0007183 9 5 0,000 0,02435868 0,12704071 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 0,02435868 0,12675329 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 0,02435868 0,12646716 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 0,02435868 0,12618233 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 0,02435868 0,12589877 ! embryonic camera-type eye development GO:0031076 8 5 0,000 0,02435868 0,12561649 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 0,02435868 0,12533547 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 0,02435868 0,1250557 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02435868 0,12477718 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,02435868 0,1244999 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,02435868 0,12422384 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 0,02435868 0,12394901 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,02435868 0,12367539 ! malate metabolic process GO:0006108 7 5 0,000 0,02435868 0,12340298 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 0,02435868 0,12313177 ! behavioral response to pain GO:0048266 7 5 0,000 0,02435868 0,12286174 ! clathrin coat assembly GO:0048268 11 5 0,000 0,02435868 0,1225929 ! phototransduction, visible light GO:0007603 6 5 0,000 0,02435868 0,12232523 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02435868 0,12205872 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 0,02435868 0,12179338 ! mating behavior GO:0007617 6 5 0,000 0,02435868 0,12152918 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,02435868 0,12126613 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 0,02435868 0,12100422 ! rhythmic behavior GO:0007622 12 5 0,000 0,02435868 0,12074343 ! copulation GO:0007620 7 5 0,000 0,02435868 0,12048377 ! glial cell fate commitment GO:0021781 12 5 0,000 0,02435868 0,12022522 ! protein maturation by protein folding GO:0022417 12 5 0,000 0,02435868 0,11996778 ! embryonic hemopoiesis GO:0035162 10 5 0,000 0,02435868 0,11971144 ! regulation of potassium ion transport GO:0043266 9 5 0,000 0,02435868 0,11945619 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 0,02435868 0,11920203 ! apoptotic cell clearance GO:0043277 13 5 0,000 0,02435868 0,11894895 ! lipoprotein particle clearance GO:0034381 9 5 0,000 0,02435868 0,11869694 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 0,02435868 0,11844599 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02435868 0,1181961 ! response to protozoan GO:0001562 9 5 0,000 0,02435868 0,11794727 ! positive regulation of glycolysis GO:0045821 11 5 0,000 0,02435868 0,11769948 ! lymph vessel development GO:0001945 7 5 0,000 0,02435868 0,11745273 ! endochondral ossification GO:0001958 12 5 0,000 0,02435868 0,11720702 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 0,02435868 0,11696232 ! parathyroid gland development GO:0060017 8 5 0,000 0,02435868 0,11671865 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 0,02435868 0,11647599 ! anagen GO:0042640 6 5 0,000 0,02435868 0,11623434 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 0,02435868 0,11599369 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 0,02435868 0,11575404 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 0,02435868 0,11551537 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! nuclear migration GO:0007097 10 5 0,000 0,02435868 0,11527768 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 0,02435868 0,11504097 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 0,02435868 0,11480523 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 0,02435868 0,11457046 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 0,02435868 0,11433664 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 0,02435868 0,11410378 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 0,02435868 0,11387186 ! cardiac muscle fiber development GO:0048739 7 5 0,000 0,02435868 0,11364088 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 0,02435868 0,11341084 ! neutrophil mediated immunity GO:0002446 6 5 0,000 0,02435868 0,11318172 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 0,02435868 0,11295354 ! ovulation GO:0030728 6 5 0,000 0,02435868 0,11272626 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 0,02435868 0,11249991 GO:0033135|regulation of peptidyl-serine phosphorylation, ! microvillus organization GO:0032528 7 5 0,000 0,02435868 0,11227446 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 8 5 0,000 0,02435868 0,11204991 ! response to pH GO:0009268 9 5 0,000 0,02435868 0,11182625 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 0,02435868 0,11160349 ! proline biosynthetic process GO:0006561 6 5 0,000 0,02435868 0,11138162 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,02435868 0,11116062 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 0,02435868 0,1109405 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,02435868 0,11072125 ! polyol catabolic process GO:0046174 7 5 0,000 0,02435868 0,11050287 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,02435868 0,11028534 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,02435868 0,11006867 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,02435868 0,10985285 ! sister chromatid cohesion GO:0007062 9 5 0,000 0,02435868 0,10963787 ! nerve growth factor processing GO:0032455 7 5 0,000 0,02435868 0,10942374 ! urea metabolic process GO:0019627 6 5 0,000 0,02435868 0,10921044 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 0,02435868 0,10899796 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,02435868 0,10878632 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 0,000 0,02435868 0,10857549 ! neutrophil activation GO:0042119 5 5 0,000 0,02435868 0,10836548 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 0,02435868 0,10815628 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 0,02435868 0,10794789 ! response to food GO:0032094 5 5 0,000 0,02435868 0,1077403 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 0,02435868 0,1075335 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02435868 0,1073275 ! paraxial mesoderm development GO:0048339 9 5 0,000 0,02435868 0,10712228 ! forebrain neuron development GO:0021884 7 5 0,000 0,02435868 0,10691785 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 0,02435868 0,1067142 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,02435868 0,10651132 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 0,02435868 0,10630921 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02435868 0,10610787 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 14 5 0,000 0,02435868 0,10590728 ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 0,02435868 0,10570746 ! nucleoside transport GO:0015858 6 5 0,000 0,02435868 0,10550839 ! nucleoside salvage GO:0043174 7 5 0,000 0,02435868 0,10531006 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 0,02435868 0,10511248 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02435868 0,10491564 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 0,02435868 0,10471954 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 0,02435868 0,10452417 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,02435868 0,10432952 ! early endosome to late endosome transport GO:0045022 11 5 0,000 0,02435868 0,1041356 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,02435868 0,1039424 ! depyrimidination GO:0045008 8 5 0,000 0,02435868 0,10374991 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 0,02435868 0,10355814 ! 5S class rRNA transcription GO:0042791 8 5 0,000 0,02435868 0,10336707 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 0,02435868 0,10317671 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02435868 0,10298705 ! neuronal ion channel clustering GO:0045161 7 5 0,000 0,02435868 0,10279808 ! sodium ion homeostasis GO:0055078 6 5 0,000 0,02435868 0,10260981 ! homeostasis of number of cells within a tissue GO:0048873 9 5 0,000 0,02435868 0,10242222 ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 0,02435868 0,10223532 ! monocyte differentiation GO:0030224 8 5 0,000 0,02435868 0,1020491 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 0,02435868 0,10186355 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02435868 0,10167868 ! centrosome duplication GO:0051298 5 5 0,000 0,02435868 0,10149448 ! response to UV-C GO:0010225 6 5 0,000 0,02435868 0,10131095 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 0,02435868 0,10112808 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 0,02435868 0,10094586 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 0,02435868 0,1007643 ! regulation of dendrite development GO:0050773 12 5 0,000 0,02435868 0,1005834 ! peptidyl-arginine modification GO:0018195 7 5 0,000 0,02435868 0,10040314 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02435868 0,10022353 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 0,02435868 0,10004456 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 0,02435868 0,09986623 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 0,02435868 0,09968853 ! regulation of dopamine secretion GO:0014059 12 5 0,000 0,02435868 0,09951146 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 0,02435868 0,09933502 ! cranial nerve morphogenesis GO:0021602 6 5 0,000 0,02435868 0,09915921 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 0,02435868 0,09898402 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,02435868 0,09880944 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 0,02435868 0,09863548 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,02435868 0,09846213 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 0,02435868 0,09828939 ! positive regulation of Rho GTPase activity GO:0032321 9 5 0,000 0,02435868 0,09811726 ! neural tube patterning GO:0021532 6 5 0,000 0,02435868 0,09794572 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 0,02435868 0,09777479 ! histone demethylation GO:0016577 9 5 0,000 0,02435868 0,09760445 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,02435868 0,0974347 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02435868 0,09726554 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 0,02435868 0,09709697 ! enteric nervous system development GO:0048484 8 5 0,000 0,02435868 0,09692899 ! establishment of planar polarity GO:0001736 6 5 0,000 0,02435868 0,09676158 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 0,02435868 0,09659475 ! muscle cell proliferation GO:0033002 8 5 0,000 0,02435868 0,09642849 ! transcription termination GO:0006353 8 5 0,000 0,02435868 0,09626281 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 0,02435868 0,09609769 ! positive regulation of pseudopodium assembly GO:0031274 13 5 0,000 0,02435868 0,09593314 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 5 5 0,000 0,02435868 0,09576915 ! regulation of respiratory burst GO:0060263 8 5 0,000 0,02435868 0,09560572 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 0,02435868 0,09544285 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,02435868 0,09528053 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,02435868 0,09511877 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 0,02435868 0,09495755 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 0,02435868 0,09479688 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 0,02435868 0,09463675 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 0,02435868 0,09447716 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02435868 0,0943181 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02435868 0,09415959 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 0,02435868 0,0940016 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 0,02435868 0,09384414 ! triglyceride catabolic process GO:0019433 6 5 0,000 0,02435868 0,09368721 ! glial cell migration GO:0008347 10 5 0,000 0,02435868 0,09353081 ! determination of adult lifespan GO:0008340 8 5 0,000 0,02435868 0,09337492 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 0,02435868 0,09321956 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,02435868 0,09306471 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,02435868 0,09291037 ! somatic stem cell maintenance GO:0035019 13 5 0,000 0,02435868 0,09275655 ! cerebellar cortex formation GO:0021697 6 5 0,000 0,02435868 0,09260323 ! neural plate development GO:0001840 6 5 0,000 0,02435868 0,09245042 ! regulation of sensory perception GO:0051931 6 5 0,000 0,02435868 0,09229811 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 0,02435868 0,09214631 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 0,02435868 0,091995 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 10 5 0,000 0,02435868 0,09184419 ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 0,02435868 0,09169387 ! sensory cilium assembly GO:0035058 6 5 0,000 0,02435868 0,09154404 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 0,02435868 0,0913947 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,02435868 0,09124585 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 0,02435868 0,09109749 ! spindle assembly GO:0051225 5 5 0,000 0,02435868 0,0909496 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 0,02435868 0,09080219 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 0,02435868 0,09065526 ! protein amino acid prenylation GO:0018346 9 5 0,000 0,02435868 0,09050881 ! organ regeneration GO:0031100 7 5 0,000 0,02435868 0,09036283 ! NAD biosynthetic process GO:0009435 7 5 0,000 0,02435868 0,09021732 ! carnitine metabolic process GO:0009437 5 5 0,000 0,02435868 0,09007227 GO:0006577|betaine metabolic process, ! positive regulation of microtubule polymerization GO:0031116 9 5 0,000 0,02435868 0,08992769 ! cellular anion homeostasis GO:0030002 6 5 0,000 0,02435868 0,08978358 GO:0055081|anion homeostasis, ! regulation of actin filament length GO:0030832 72 50 1,000 0,02515232 0,09256053 ! skeletal muscle fiber development GO:0048741 73 50 1,000 0,02515232 0,09241267 ! membrane fusion GO:0006944 80 50 1,000 0,02515232 0,09226529 ! negative regulation of cytoskeleton organization GO:0051494 84 50 1,000 0,02515232 0,09211837 ! lipid modification GO:0030258 73 50 1,000 0,02515232 0,09197191 ! positive regulation of growth GO:0045927 67 50 1,000 0,02515232 0,09182593 ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 1,000 0,02609655 0,09512214 ! muscle fiber development GO:0048747 74 51 1,000 0,02609655 0,09497163 ! positive regulation of cell migration GO:0030335 92 51 1,000 0,02609655 0,0948216 ! positive regulation of organelle organization GO:0010638 82 51 1,000 0,02609655 0,09467204 ! negative regulation of cell motion GO:0051271 104 51 1,000 0,02609655 0,09452295 ! regulation of cellular component size GO:0032535 74 52 1,000 0,02705503 0,09784051 ! aging GO:0007568 79 52 1,000 0,02705503 0,09768692 ! nucleotide-excision repair GO:0006289 64 52 1,000 0,02705503 0,0975338 ! regulation of mitosis GO:0007088 84 54 1,000 0,02901408 0,10443251 GO:0051783|regulation of nuclear division, ! DNA catabolic process GO:0006308 67 54 1,000 0,02901408 0,10426933 ! detection of external stimulus GO:0009581 66 54 1,000 0,02901408 0,10410667 ! tRNA transcription GO:0009304 11 6 0,000 0,02915957 0,10446573 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 0,02915957 0,10430327 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 8 6 0,000 0,02915957 0,10414131 ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 0,02915957 0,10397985 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,02915957 0,10381889 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 0,02915957 0,10365842 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 0,02915957 0,10349846 ! cytokinesis during cell cycle GO:0033205 9 6 0,000 0,02915957 0,10333898 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 0,02915957 0,10318 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 0,02915957 0,10302151 ! positive regulation of axon extension GO:0045773 8 6 0,000 0,02915957 0,1028635 ! prostate gland development GO:0030850 9 6 0,000 0,02915957 0,10270597 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 0,02915957 0,10254893 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 0,02915957 0,10239237 ! forebrain neuron differentiation GO:0021879 9 6 0,000 0,02915957 0,10223628 GO:0021872|generation of neurons in the forebrain, ! male meiosis GO:0007140 7 6 0,000 0,02915957 0,10208067 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 0,02915957 0,10192553 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 0,02915957 0,10177087 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 0,02915957 0,10161667 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 0,02915957 0,10146294 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 0,02915957 0,10130967 ! neuron adhesion GO:0007158 9 6 0,000 0,02915957 0,10115686 ! establishment of tissue polarity GO:0007164 7 6 0,000 0,02915957 0,10100452 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 0,02915957 0,10085263 ! signal peptide processing GO:0006465 8 6 0,000 0,02915957 0,1007012 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 0,02915957 0,10055023 ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 0,02915957 0,1003997 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 0,02915957 0,10024963 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 0,02915957 0,1001 ! opsonization GO:0008228 8 6 0,000 0,02915957 0,09995082 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 0,02915957 0,09980208 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 0,02915957 0,09965379 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 0,02915957 0,09950594 ! protein amino acid dealkylation GO:0008214 11 6 0,000 0,02915957 0,09935852 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 0,02915957 0,09921154 ! photoreceptor cell development GO:0042461 10 6 0,000 0,02915957 0,09906499 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 0,02915957 0,09891888 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 0,02915957 0,0987732 ! mechanosensory behavior GO:0007638 8 6 0,000 0,02915957 0,09862794 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 0,02915957 0,09848311 ! negative regulation of endocytosis GO:0045806 8 6 0,000 0,02915957 0,09833871 ! response to interferon-gamma GO:0034341 12 6 0,000 0,02915957 0,09819473 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 0,02915957 0,09805117 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 0,02915957 0,09790803 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,02915957 0,09776531 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 0,02915957 0,097623 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 0,02915957 0,09748111 ! cGMP-mediated signaling GO:0019934 10 6 0,000 0,02915957 0,09733962 ! activation of MAPKKK activity GO:0000185 10 6 0,000 0,02915957 0,09719855 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 0,02915957 0,09705789 ! thymic T cell selection GO:0045061 12 6 0,000 0,02915957 0,09691763 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 0,02915957 0,09677778 ! drug transport GO:0015893 6 6 0,000 0,02915957 0,09663833 ! cysteine metabolic process GO:0006534 7 6 0,000 0,02915957 0,09649928 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 0,02915957 0,09636063 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,02915957 0,09622238 ! histidine metabolic process GO:0006547 6 6 0,000 0,02915957 0,09608453 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 0,02915957 0,09594707 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 0,02915957 0,09581 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 0,000 0,02915957 0,09567332 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! glycine catabolic process GO:0006546 9 6 0,000 0,02915957 0,09553704 ! adenohypophysis development GO:0021984 10 6 0,000 0,02915957 0,09540114 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 0,02915957 0,09526563 ! hyperosmotic response GO:0006972 8 6 0,000 0,02915957 0,0951305 ! microtubule nucleation GO:0007020 10 6 0,000 0,02915957 0,09499575 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 0,02915957 0,09486139 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 0,02915957 0,0947274 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 0,02915957 0,09459379 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 0,02915957 0,09446056 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 0,02915957 0,09432771 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 0,000 0,02915957 0,09419523 ! response to dietary excess GO:0002021 7 6 0,000 0,02915957 0,09406311 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 0,02915957 0,09393137 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 0,02915957 0,0938 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 0,02915957 0,093669 ! glycerol ether catabolic process GO:0044269 8 6 0,000 0,02915957 0,09353835 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 0,02915957 0,09340808 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,02915957 0,09327816 ! neuron apoptosis GO:0051402 8 6 0,000 0,02915957 0,09314861 ! organic alcohol transport GO:0015850 9 6 0,000 0,02915957 0,09301942 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 0,000 0,02915957 0,09289058 ! T cell mediated immunity GO:0002456 12 6 0,000 0,02915957 0,0927621 ! male sex determination GO:0030238 9 6 0,000 0,02915957 0,09263398 ! carnitine transport GO:0015879 8 6 0,000 0,02915957 0,09250621 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 0,02915957 0,09237879 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 0,02915957 0,09225172 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,02915957 0,092125 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 0,02915957 0,09199863 ! positive regulation of exocytosis GO:0045921 6 6 0,000 0,02915957 0,0918726 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 0,02915957 0,09174692 ! parturition GO:0007567 12 6 0,000 0,02915957 0,09162159 ! negative regulation of translational initiation GO:0045947 7 6 0,000 0,02915957 0,09149659 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 0,02915957 0,09137194 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 0,02915957 0,09124762 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 0,000 0,02915957 0,09112364 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 14 6 0,000 0,02915957 0,091 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 0,02915957 0,09087669 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 0,02915957 0,09075372 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 0,02915957 0,09063108 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 0,02915957 0,09050877 ! macrophage differentiation GO:0030225 10 6 0,000 0,02915957 0,09038679 ! astrocyte development GO:0014002 14 6 0,000 0,02915957 0,09026514 ! hyaluronan metabolic process GO:0030212 6 6 0,000 0,02915957 0,09014382 ! purine base biosynthetic process GO:0009113 14 6 0,000 0,02915957 0,09002282 ! interaction with symbiont GO:0051702 8 6 0,000 0,02915957 0,08990215 ! anterograde axon cargo transport GO:0008089 8 6 0,000 0,02915957 0,08978179 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,02915957 0,08966177 ! eating behavior GO:0042755 6 6 0,000 0,02915957 0,08954206 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 0,02915957 0,08942267 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 0,02915957 0,0893036 ! response to copper ion GO:0046688 9 6 0,000 0,02915957 0,08918484 ! DNA topological change GO:0006265 8 6 0,000 0,02915957 0,0890664 ! response to exogenous dsRNA GO:0043330 8 6 0,000 0,02915957 0,08894828 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,02915957 0,08883046 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,02915957 0,08871296 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 0,02915957 0,08859577 ! negative regulation of focal adhesion formation GO:0051895 16 6 0,000 0,02915957 0,08847889 ! nucleoside catabolic process GO:0009164 6 6 0,000 0,02915957 0,08836232 ! gas homeostasis GO:0033483 11 6 0,000 0,02915957 0,08824605 ! hair follicle maturation GO:0048820 7 6 0,000 0,02915957 0,08813009 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 0,02915957 0,08801444 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 0,02915957 0,08789908 ! Schwann cell development GO:0014044 14 6 0,000 0,02915957 0,08778403 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 0,02915957 0,08766928 ! dendrite morphogenesis GO:0048813 9 6 0,000 0,02915957 0,08755483 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,02915957 0,08744068 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 0,02915957 0,08732682 ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 0,02915957 0,08721326 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 0,02915957 0,0871 ! histone ubiquitination GO:0016574 7 6 0,000 0,02915957 0,08698703 ! regulation of meiosis GO:0040020 10 6 0,000 0,02915957 0,08687435 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 0,02915957 0,08676197 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 0,02915957 0,08664987 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 0,02915957 0,08653807 ! regulation of mast cell activation GO:0033003 6 6 0,000 0,02915957 0,08642655 ! membrane to membrane docking GO:0022614 12 6 0,000 0,02915957 0,08631532 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 0,02915957 0,08620437 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 0,02915957 0,08609371 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 0,02915957 0,08598333 ! receptor internalization GO:0031623 9 6 0,000 0,02915957 0,08587324 ! neutrophil homeostasis GO:0001780 6 6 0,000 0,02915957 0,08576343 ! coenzyme A metabolic process GO:0015936 9 6 0,000 0,02915957 0,0856539 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,02915957 0,08554464 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 0,000 0,02915957 0,08543567 ! protein deubiquitination GO:0016579 8 6 0,000 0,02915957 0,08532697 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 0,02915957 0,08521855 ! peptidyl-histidine modification GO:0018202 9 6 0,000 0,02915957 0,08511041 ! axonal fasciculation GO:0007413 9 6 0,000 0,02915957 0,08500254 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 0,02915957 0,08489494 ! thiamin metabolic process GO:0006772 6 6 0,000 0,02915957 0,08478761 ! midbrain development GO:0030901 6 6 0,000 0,02915957 0,08468056 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 0,02915957 0,08457377 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,02915957 0,08446726 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 0,02915957 0,08436101 ! progesterone metabolic process GO:0042448 8 6 0,000 0,02915957 0,08425503 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 0,02915957 0,08414931 ! glycolipid catabolic process GO:0019377 13 6 0,000 0,02915957 0,08404386 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 0,02915957 0,08393867 ! positive regulation of glucose import GO:0046326 6 6 0,000 0,02915957 0,08383375 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 0,02915957 0,08372909 ! adult feeding behavior GO:0008343 6 6 0,000 0,02915957 0,08362469 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 0,02915957 0,08352055 ! blastocyst growth GO:0001832 15 6 0,000 0,02915957 0,08341667 ! pigment granule transport GO:0051904 12 6 0,000 0,02915957 0,08331304 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 0,02915957 0,08320968 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 0,02915957 0,08310657 ! catecholamine transport GO:0051937 7 6 0,000 0,02915957 0,08300371 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,02915957 0,08290111 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 0,02915957 0,08279877 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 0,02915957 0,08269667 ! negative regulation of B cell activation GO:0050869 9 6 0,000 0,02915957 0,08259483 ! protein prenylation GO:0018342 10 6 0,000 0,02915957 0,08249324 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,02915957 0,08239189 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 0,000 0,02915957 0,0822908 ! regulation of microtubule polymerization GO:0031113 11 6 0,000 0,02915957 0,08218995 ! positive regulation of coagulation GO:0050820 11 6 0,000 0,02915957 0,08208935 ! regulation of lipid metabolic process GO:0019216 84 56 1,000 0,0310282 0,0872431 ! positive regulation of cell motion GO:0051272 99 56 1,000 0,0310282 0,08713657 ! chromosome segregation GO:0007059 83 57 1,000 0,03205552 0,08991183 ! camera-type eye development GO:0043010 88 57 1,000 0,03205552 0,08980231 ! response to peptide hormone stimulus GO:0043434 84 57 1,000 0,03205552 0,08969307 ! developmental maturation GO:0021700 75 57 1,000 0,03205552 0,08958408 ! steroid hormone receptor signaling pathway GO:0030518 96 58 1,000 0,03309615 0,09238003 ! protein maturation by peptide bond cleavage GO:0051605 76 58 1,000 0,03309615 0,09226806 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 0,000 0,0339371 0,09449799 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 0,0339371 0,09438373 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 0,0339371 0,09426974 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 0,0339371 0,09415602 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 0,0339371 0,09404258 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 0,0339371 0,09392941 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,0339371 0,09381652 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 0,0339371 0,09370389 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,0339371 0,09359154 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 0,0339371 0,09347945 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 0,0339371 0,09336763 ! reproductive behavior GO:0019098 12 7 0,000 0,0339371 0,09325608 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 0,0339371 0,0931448 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 0,0339371 0,09303378 ! regulation of smooth muscle cell migration GO:0014910 19 7 0,000 0,0339371 0,09292302 ! oligopeptide transport GO:0006857 11 7 0,000 0,0339371 0,09281253 ! protein amino acid sulfation GO:0006477 9 7 0,000 0,0339371 0,09270231 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 0,0339371 0,09259234 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! negative regulation of JAK-STAT cascade GO:0046426 15 7 0,000 0,0339371 0,09248263 ! RNA methylation GO:0001510 11 7 0,000 0,0339371 0,09237318 ! pericardium development GO:0060039 8 7 0,000 0,0339371 0,092264 ! macrophage chemotaxis GO:0048246 10 7 0,000 0,0339371 0,09215507 ! fibril organization GO:0043206 13 7 0,000 0,0339371 0,09204639 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 0,0339371 0,09193798 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,0339371 0,09182981 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 0,0339371 0,0917219 ! lipoprotein transport GO:0042953 9 7 0,000 0,0339371 0,09161425 ! cerebral cortex cell migration GO:0021795 11 7 0,000 0,0339371 0,09150685 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,0339371 0,0913997 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,0339371 0,0912928 ! estrogen metabolic process GO:0008210 14 7 0,000 0,0339371 0,09118615 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 0,0339371 0,09107974 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 0,0339371 0,09097359 ! chemosensory behavior GO:0007635 9 7 0,000 0,0339371 0,09086768 ! microtubule bundle formation GO:0001578 8 7 0,000 0,0339371 0,09076202 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 0,0339371 0,09065661 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 0,0339371 0,09055144 ! leukocyte degranulation GO:0043299 10 7 0,000 0,0339371 0,09044651 ! bile acid and bile salt transport GO:0015721 9 7 0,000 0,0339371 0,09034183 ! reflex GO:0060004 12 7 0,000 0,0339371 0,09023739 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,0339371 0,09013319 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 0,0339371 0,09002923 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 0,0339371 0,08992551 ! glycerolipid catabolic process GO:0046503 9 7 0,000 0,0339371 0,08982203 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,0339371 0,08971878 ! spinal cord patterning GO:0021511 7 7 0,000 0,0339371 0,08961578 ! hemoglobin metabolic process GO:0020027 10 7 0,000 0,0339371 0,08951301 ! adrenal gland development GO:0030325 17 7 0,000 0,0339371 0,08941047 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 0,0339371 0,08930817 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 0,0339371 0,0892061 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 0,0339371 0,08910427 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 0,0339371 0,08900267 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 0,0339371 0,0889013 ! endosome organization GO:0007032 10 7 0,000 0,0339371 0,08880016 ! thyroid hormone generation GO:0006590 11 7 0,000 0,0339371 0,08869925 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 0,0339371 0,08859857 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 0,0339371 0,08849812 ! regulation of pigmentation during development GO:0048070 15 7 0,000 0,0339371 0,08839789 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,0339371 0,0882979 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 0,0339371 0,08819813 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,0339371 0,08809858 ! galactose metabolic process GO:0006012 10 7 0,000 0,0339371 0,08799926 ! vesicle fusion GO:0006906 15 7 0,000 0,0339371 0,08790016 ! intracellular pH reduction GO:0051452 10 7 0,000 0,0339371 0,08780128 GO:0045851|pH reduction, ! organ growth GO:0035265 11 7 0,000 0,0339371 0,08770263 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 0,0339371 0,0876042 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 0,000 0,0339371 0,08750599 ! Rac protein signal transduction GO:0016601 7 7 0,000 0,0339371 0,087408 ! retinol metabolic process GO:0042572 9 7 0,000 0,0339371 0,08731022 ! behavioral fear response GO:0001662 13 7 0,000 0,0339371 0,08721267 GO:0002209|behavioral defense response, ! positive regulation of mitotic cell cycle GO:0045931 11 7 0,000 0,0339371 0,08711534 ! negative regulation of muscle contraction GO:0045932 12 7 0,000 0,0339371 0,08701822 ! rRNA modification GO:0000154 12 7 0,000 0,0339371 0,08692132 ! protein heterooligomerization GO:0051291 10 7 0,000 0,0339371 0,08682463 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,0339371 0,08672816 ! response to UV-B GO:0010224 11 7 0,000 0,0339371 0,0866319 ! protein retention in ER lumen GO:0006621 12 7 0,000 0,0339371 0,08653585 ! intermediate filament organization GO:0045109 11 7 0,000 0,0339371 0,08644002 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 0,0339371 0,0863444 ! cardiac muscle cell development GO:0055013 9 7 0,000 0,0339371 0,086249 ! fibrinolysis GO:0042730 9 7 0,000 0,0339371 0,0861538 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 0,000 0,0339371 0,08605881 ! regulation of circadian rhythm GO:0042752 11 7 0,000 0,0339371 0,08596403 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 0,0339371 0,08586946 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 0,0339371 0,0857751 ! response to tropane GO:0014073 13 7 0,000 0,0339371 0,08568095 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 0,0339371 0,085587 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 0,0339371 0,08549325 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 0,0339371 0,08539972 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 0,0339371 0,08530638 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 0,0339371 0,08521325 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 0,0339371 0,08512033 ! mast cell activation GO:0045576 9 7 0,000 0,0339371 0,0850276 ! multicellular organismal aging GO:0010259 11 7 0,000 0,0339371 0,08493508 ! regulation of focal adhesion formation GO:0051893 17 7 0,000 0,0339371 0,08484276 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 0,0339371 0,08475064 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 0,0339371 0,08465872 ! positive regulation of monooxygenase activity GO:0032770 11 7 0,000 0,0339371 0,084567 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 0,0339371 0,08447548 ! establishment of nucleus localization GO:0040023 13 7 0,000 0,0339371 0,08438415 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 0,0339371 0,08429302 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 0,0339371 0,08420209 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 0,0339371 0,08411136 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 0,0339371 0,08402082 ! regulation of lipid transport GO:0032368 13 7 0,000 0,0339371 0,08393047 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 0,0339371 0,08384032 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 0,0339371 0,08375037 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 0,000 0,0339371 0,0836606 ! peptidyl-threonine modification GO:0018210 18 7 0,000 0,0339371 0,08357103 ! diuresis GO:0030146 12 7 0,000 0,0339371 0,08348165 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 0,0339371 0,08339246 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of epidermis development GO:0045684 11 7 0,000 0,0339371 0,08330346 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,0339371 0,08321465 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 0,0339371 0,08312603 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,0339371 0,0830376 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,0339371 0,08294935 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,0339371 0,0828613 ! regulation of synaptogenesis GO:0051963 10 7 0,000 0,0339371 0,08277343 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 0,0339371 0,08268574 ! dopamine biosynthetic process GO:0042416 15 7 0,000 0,0339371 0,08259824 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 0,0339371 0,08251093 ! lymph node development GO:0048535 9 7 0,000 0,0339371 0,0824238 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 0,0339371 0,08233686 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 0,0339371 0,0822501 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,0339371 0,08216352 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 0,0339371 0,08207712 ! endosome to lysosome transport GO:0008333 10 7 0,000 0,0339371 0,0819909 ! ATP catabolic process GO:0006200 10 7 0,000 0,0339371 0,08190487 ! trophectodermal cell differentiation GO:0001829 8 7 0,000 0,0339371 0,08181902 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 0,0339371 0,08173334 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 0,0339371 0,08164785 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 0,0339371 0,08156253 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 0,0339371 0,08147739 ! muscle adaptation GO:0043500 12 7 0,000 0,0339371 0,08139243 ! amino sugar catabolic process GO:0046348 9 7 0,000 0,0339371 0,08130765 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 0,0339371 0,08122304 ! retina homeostasis GO:0001895 9 7 0,000 0,0339371 0,08113861 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 0,0339371 0,08105435 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 0,0339371 0,08097027 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 0,0339371 0,08088636 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 0,0339371 0,08080263 ! behavioral response to nicotine GO:0035095 11 7 0,000 0,0339371 0,08071907 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 0,0339371 0,08063568 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,0339371 0,08055247 ! activation of MAPK activity GO:0000187 84 59 1,000 0,03414993 0,08097407 ! actin filament organization GO:0007015 95 59 1,000 0,03414993 0,08089067 ! myeloid cell differentiation GO:0030099 85 59 1,000 0,03414993 0,08080745 ! phosphoinositide metabolic process GO:0030384 87 60 1,000 0,03521671 0,08324609 ! regulation of cellular response to stress GO:0080135 85 61 1,000 0,03629635 0,08571006 ! meiosis GO:0007126 96 61 1,000 0,03629635 0,08562215 GO:0051327|M phase of meiotic cell cycle, ! cell-matrix adhesion GO:0007160 114 61 1,000 0,03629635 0,08553442 ! lipoprotein metabolic process GO:0042157 89 61 1,000 0,03629635 0,08544687 ! homeostasis of number of cells GO:0048872 84 61 1,000 0,03629635 0,08535951 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 1,000 0,03629635 0,08527231 ! lymphocyte mediated immunity GO:0002449 88 62 1,000 0,03738868 0,08774894 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 1,000 0,03738868 0,08765949 ! meiotic cell cycle GO:0051321 97 62 1,000 0,03738868 0,08757023 ! regulation of transcription factor activity GO:0051090 97 63 1,000 0,03849357 0,09006633 GO:0090046|regulation of transcription regulator activity, ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 1,000 0,03849357 0,0899748 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 0,03869141 0,09034541 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,03869141 0,09025379 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 0,000 0,03869141 0,09016234 ! axon extension GO:0048675 11 8 0,000 0,03869141 0,09007109 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 0,000 0,03869141 0,08998001 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 0,03869141 0,08988912 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 0,000 0,03869141 0,08979842 GO:0046579|positive regulation of Ras protein signal transduction, ! associative learning GO:0008306 15 8 0,000 0,03869141 0,0897079 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,03869141 0,08961756 ! cell proliferation in forebrain GO:0021846 10 8 0,000 0,03869141 0,0895274 ! positive regulation of B cell proliferation GO:0030890 11 8 0,000 0,03869141 0,08943742 ! phosphate transport GO:0006817 10 8 0,000 0,03869141 0,08934762 ! N-glycan processing GO:0006491 12 8 0,000 0,03869141 0,08925801 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,03869141 0,08916857 ! UTP metabolic process GO:0046051 8 8 0,000 0,03869141 0,08907931 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 0,03869141 0,08899023 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 0,03869141 0,08890133 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 10 8 0,000 0,03869141 0,08881261 ! succinate metabolic process GO:0006105 14 8 0,000 0,03869141 0,08872406 ! smoothened signaling pathway GO:0007224 8 8 0,000 0,03869141 0,08863569 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,03869141 0,0885475 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,03869141 0,08845948 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 0,03869141 0,08837163 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,03869141 0,08828396 ! ganglioside metabolic process GO:0001573 15 8 0,000 0,03869141 0,08819646 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 0,000 0,03869141 0,08810914 ! pseudouridine synthesis GO:0001522 9 8 0,000 0,03869141 0,08802199 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,03869141 0,08793501 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,03869141 0,08784821 ! endothelial cell differentiation GO:0045446 14 8 0,000 0,03869141 0,08776157 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,03869141 0,08767511 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 0,000 0,03869141 0,08758881 ! astrocyte differentiation GO:0048708 16 8 0,000 0,03869141 0,08750269 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 0,03869141 0,08741673 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,03869141 0,08733095 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,03869141 0,08724533 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 0,03869141 0,08715988 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,03869141 0,08707459 ! melanin metabolic process GO:0006582 12 8 0,000 0,03869141 0,08698948 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 0,03869141 0,08690452 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,03869141 0,08681974 ! macrophage activation GO:0042116 12 8 0,000 0,03869141 0,08673512 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,03869141 0,08665067 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,03869141 0,08656637 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! multicellular organism growth GO:0035264 14 8 0,000 0,03869141 0,08648225 ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 0,03869141 0,08639828 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 0,03869141 0,08631448 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 0,03869141 0,08623085 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 0,03869141 0,08614737 ! ruffle organization GO:0031529 11 8 0,000 0,03869141 0,08606406 ! osteoblast development GO:0002076 13 8 0,000 0,03869141 0,0859809 ! positive regulation of vasodilation GO:0045909 12 8 0,000 0,03869141 0,08589791 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,03869141 0,08581508 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 0,03869141 0,0857324 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 0,03869141 0,08564989 ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 0,03869141 0,08556753 ! Schwann cell differentiation GO:0014037 17 8 0,000 0,03869141 0,08548533 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,03869141 0,08540329 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 0,03869141 0,08532141 ! brain morphogenesis GO:0048854 20 8 0,000 0,03869141 0,08523969 ! oligodendrocyte development GO:0014003 8 8 0,000 0,03869141 0,08515812 ! segment specification GO:0007379 10 8 0,000 0,03869141 0,0850767 ! cellular extravasation GO:0045123 11 8 0,000 0,03869141 0,08499545 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 0,03869141 0,08491434 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 0,03869141 0,0848334 ! snRNA metabolic process GO:0016073 10 8 0,000 0,03869141 0,0847526 GO:0016180|snRNA processing, ! regulation of interleukin-4 production GO:0032673 16 8 0,000 0,03869141 0,08467196 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 0,03869141 0,08459148 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,03869141 0,08451114 ! regulation of mitochondrial membrane potential GO:0051881 11 8 0,000 0,03869141 0,08443096 ! nucleosome disassembly GO:0006337 12 8 0,000 0,03869141 0,08435093 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 0,03869141 0,08427105 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of Ras GTPase activity GO:0032320 20 8 0,000 0,03869141 0,08419133 ! protein import into peroxisome matrix GO:0016558 14 8 0,000 0,03869141 0,08411175 ! icosanoid secretion GO:0032309 12 8 0,000 0,03869141 0,08403233 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 11 8 0,000 0,03869141 0,08395305 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,03869141 0,08387392 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 0,03869141 0,08379495 ! cerebellum morphogenesis GO:0021587 9 8 0,000 0,03869141 0,08371612 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 0,03869141 0,08363744 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 0,03869141 0,0835589 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 0,03869141 0,08348052 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 0,03869141 0,08340228 ! sterol catabolic process GO:0016127 9 8 0,000 0,03869141 0,08332419 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 0,03869141 0,08324624 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 0,03869141 0,08316844 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 0,03869141 0,08309079 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 0,03869141 0,08301328 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,03869141 0,08293591 ! prophase GO:0051324 11 8 0,000 0,03869141 0,08285869 ! S phase GO:0051320 8 8 0,000 0,03869141 0,08278161 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 0,03869141 0,08270468 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,03869141 0,08262789 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,03869141 0,08255124 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,03869141 0,08247473 ! hormone catabolic process GO:0042447 13 8 0,000 0,03869141 0,08239836 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,03869141 0,08232214 ! myeloid cell homeostasis GO:0002262 8 8 0,000 0,03869141 0,08224606 ! regulation of fibrinolysis GO:0051917 13 8 0,000 0,03869141 0,08217011 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 0,03869141 0,08209431 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,03869141 0,08201865 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,03869141 0,08194312 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,03869141 0,08186774 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 0,03869141 0,08179249 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 0,03869141 0,08171739 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,03869141 0,08164242 ! lamellipodium assembly GO:0030032 9 8 0,000 0,03869141 0,08156758 ! regulation of embryonic development GO:0045995 16 8 0,000 0,03869141 0,08149289 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,03869141 0,08141833 GO:0000076|DNA replication checkpoint, ! mitochondrion localization GO:0051646 12 8 0,000 0,03869141 0,08134391 ! regulation of actin cytoskeleton organization GO:0032956 97 64 1,000 0,03961086 0,08320089 ! B cell activation GO:0042113 104 65 1,000 0,04074041 0,0854954 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 1,000 0,04074041 0,08541746 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 1,000 0,04074041 0,08533967 ! regulation of MAPKKK cascade GO:0043408 101 65 1,000 0,04074041 0,08526201 ! regulation of actin filament-based process GO:0032970 99 66 1,000 0,04188209 0,08757163 ! cell-substrate adhesion GO:0031589 121 66 1,000 0,04188209 0,0874921 ! axon guidance GO:0007411 99 66 1,000 0,04188209 0,0874127 ! regulation of Rho protein signal transduction GO:0035023 111 66 1,000 0,04188209 0,08733345 ! regulation of neuron differentiation GO:0045664 107 67 1,000 0,04303573 0,08965777 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,04342258 0,09038184 ! regulation of developmental growth GO:0048638 13 9 0,000 0,04342258 0,09030012 ! positive regulation of glucose metabolic process GO:0010907 15 9 0,000 0,04342258 0,09021855 ! telencephalon cell migration GO:0022029 16 9 0,000 0,04342258 0,09013712 ! regulation of epithelial cell differentiation GO:0030856 13 9 0,000 0,04342258 0,09005585 ! pentose-phosphate shunt GO:0006098 12 9 0,000 0,04342258 0,08997472 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 0,04342258 0,08989373 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 0,04342258 0,08981289 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,04342258 0,0897322 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! positive regulation of GTPase activity GO:0043547 21 9 0,000 0,04342258 0,08965165 ! SMAD protein nuclear translocation GO:0007184 15 9 0,000 0,04342258 0,08957124 ! GTP metabolic process GO:0046039 9 9 0,000 0,04342258 0,08949098 ! elastic fiber assembly GO:0048251 13 9 0,000 0,04342258 0,08941086 ! social behavior GO:0035176 14 9 0,000 0,04342258 0,08933089 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 0,04342258 0,08925106 ! artery development GO:0060840 19 9 0,000 0,04342258 0,08917137 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 0,04342258 0,08909182 ! regulation of glycolysis GO:0006110 15 9 0,000 0,04342258 0,08901242 ! response to pain GO:0048265 16 9 0,000 0,04342258 0,08893316 ! protein complex disassembly GO:0043241 17 9 0,000 0,04342258 0,08885403 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,04342258 0,08877505 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,04342258 0,08869621 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,04342258 0,08861751 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,04342258 0,08853895 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,04342258 0,08846053 ! ventral spinal cord development GO:0021517 11 9 0,000 0,04342258 0,08838224 ! protein targeting to ER GO:0045047 19 9 0,000 0,04342258 0,0883041 ! T cell selection GO:0045058 18 9 0,000 0,04342258 0,08822609 ! endoderm development GO:0007492 12 9 0,000 0,04342258 0,08814822 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,04342258 0,08807049 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,04342258 0,08799289 ! arginine catabolic process GO:0006527 10 9 0,000 0,04342258 0,08791543 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 0,04342258 0,08783811 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 0,04342258 0,08776093 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 0,04342258 0,08768388 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,04342258 0,08760696 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 12 9 0,000 0,04342258 0,08753018 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 0,04342258 0,08745353 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 0,000 0,04342258 0,08737702 ! regulation of stress fiber formation GO:0051492 20 9 0,000 0,04342258 0,08730064 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,04342258 0,0872244 ! mannose metabolic process GO:0006013 9 9 0,000 0,04342258 0,08714828 ! substrate-bound cell migration GO:0006929 10 9 0,000 0,04342258 0,08707231 ! receptor clustering GO:0043113 15 9 0,000 0,04342258 0,08699646 ! epithelial cell development GO:0002064 10 9 0,000 0,04342258 0,08692074 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 0,04342258 0,08684516 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,04342258 0,08676971 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 0,04342258 0,08669439 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,04342258 0,0866192 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 0,04342258 0,08654414 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 0,04342258 0,08646921 ! alpha-beta T cell differentiation GO:0046632 14 9 0,000 0,04342258 0,08639441 ! positive regulation of phagocytosis GO:0050766 11 9 0,000 0,04342258 0,08631974 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 0,000 0,04342258 0,08624519 ! blastoderm segmentation GO:0007350 11 9 0,000 0,04342258 0,08617078 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,04342258 0,08609649 ! DNA ligation GO:0006266 14 9 0,000 0,04342258 0,08602234 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 0,04342258 0,08594831 ! response to amine stimulus GO:0014075 13 9 0,000 0,04342258 0,08587441 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 0,04342258 0,08580063 ! erythrocyte development GO:0048821 11 9 0,000 0,04342258 0,08572698 ! renal water homeostasis GO:0003091 14 9 0,000 0,04342258 0,08565346 ! postreplication repair GO:0006301 11 9 0,000 0,04342258 0,08558006 ! mRNA cleavage GO:0006379 13 9 0,000 0,04342258 0,08550679 ! hindbrain morphogenesis GO:0021575 12 9 0,000 0,04342258 0,08543365 ! regulation of hormone metabolic process GO:0032350 15 9 0,000 0,04342258 0,08536063 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,04342258 0,08528773 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 0,04342258 0,08521496 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 0,04342258 0,08514231 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 0,04342258 0,08506979 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 0,000 0,04342258 0,08499739 ! acid secretion GO:0046717 14 9 0,000 0,04342258 0,08492511 ! musculoskeletal movement GO:0050881 11 9 0,000 0,04342258 0,08485296 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 0,04342258 0,08478093 ! methionine biosynthetic process GO:0009086 10 9 0,000 0,04342258 0,08470902 ! purine base metabolic process GO:0006144 18 9 0,000 0,04342258 0,08463723 ! oocyte differentiation GO:0009994 12 9 0,000 0,04342258 0,08456557 GO:0048599|oocyte development, ! thymus development GO:0048538 15 9 0,000 0,04342258 0,08449402 ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 0,04342258 0,0844226 ! spleen development GO:0048536 15 9 0,000 0,04342258 0,0843513 ! anterior/posterior axis specification GO:0009948 11 9 0,000 0,04342258 0,08428011 ! regulation of RNA splicing GO:0043484 14 9 0,000 0,04342258 0,08420905 ! detection of calcium ion GO:0005513 13 9 0,000 0,04342258 0,08413811 ! blastocyst formation GO:0001825 12 9 0,000 0,04342258 0,08406728 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,04342258 0,08399658 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 0,000 0,04342258 0,08392599 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 0,04342258 0,08385553 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,04342258 0,08378518 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,04342258 0,08371495 ! positive regulation of amine transport GO:0051954 15 9 0,000 0,04342258 0,08364484 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 0,04342258 0,08357484 ! prepulse inhibition GO:0060134 14 9 0,000 0,04342258 0,08350496 ! embryonic placenta development GO:0001892 12 9 0,000 0,04342258 0,0834352 ! positive regulation of protein polymerization GO:0032273 15 9 0,000 0,04342258 0,08336555 ! insulin secretion GO:0030073 17 9 0,000 0,04342258 0,08329602 ! sequestering of metal ion GO:0051238 11 9 0,000 0,04342258 0,08322661 ! response to nicotine GO:0035094 16 9 0,000 0,04342258 0,08315731 ! establishment of cell polarity GO:0030010 12 9 0,000 0,04342258 0,08308813 ! nucleus localization GO:0051647 15 9 0,000 0,04342258 0,08301906 ! regulation of synapse organization GO:0050807 12 9 0,000 0,04342258 0,08295011 ! localization within membrane GO:0051668 15 9 0,000 0,04342258 0,08288127 ! acute inflammatory response GO:0002526 92 68 1,000 0,0442012 0,08429749 ! learning or memory GO:0007611 123 68 1,000 0,0442012 0,08422765 ! response to drug GO:0042493 108 69 1,000 0,04537837 0,08639921 ! positive regulation of ligase activity GO:0051351 99 69 1,000 0,04537837 0,08632775 ! response to metal ion GO:0010038 103 70 1,000 0,04656708 0,08851594 ! humoral immune response GO:0006959 86 70 1,000 0,04656708 0,08844285 ! eye development GO:0001654 111 70 1,000 0,04656708 0,08836988 ! phosphoinositide-mediated signaling GO:0048015 109 71 1,000 0,04776721 0,09057261 ! muscle cell differentiation GO:0042692 104 71 1,000 0,04776721 0,090498 ! leukocyte mediated immunity GO:0002443 99 71 1,000 0,04776721 0,09042352 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 1,000 0,04776721 0,09034915 ! lymphocyte differentiation GO:0030098 113 71 1,000 0,04776721 0,09027492 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,04813074 0,09088727 ! neuron fate specification GO:0048665 11 10 0,000 0,04813074 0,09081271 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 0,04813074 0,09073828 ! thyroid gland development GO:0030878 19 10 0,000 0,04813074 0,09066396 ! regulation of B cell proliferation GO:0030888 15 10 0,000 0,04813074 0,09058977 ! regulation of phosphatase activity GO:0010921 21 10 0,000 0,04813074 0,0905157 ! synapsis GO:0007129 13 10 0,000 0,04813074 0,09044175 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 0,04813074 0,09036792 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 0,04813074 0,09029421 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,04813074 0,09022062 GO:0007520|myoblast fusion, ! hair follicle morphogenesis GO:0031069 17 10 0,000 0,04813074 0,09014715 ! sulfate transport GO:0008272 12 10 0,000 0,04813074 0,0900738 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 0,04813074 0,09000057 GO:0048200|Golgi transport vesicle coating, ! regulation of cell projection assembly GO:0060491 20 10 0,000 0,04813074 0,08992746 ! androgen metabolic process GO:0008209 13 10 0,000 0,04813074 0,08985446 ! phospholipid efflux GO:0033700 16 10 0,000 0,04813074 0,08978159 ! positive regulation of heart contraction GO:0045823 14 10 0,000 0,04813074 0,08970883 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 0,04813074 0,08963619 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 0,000 0,04813074 0,08956367 GO:0010812|negative regulation of cell-substrate adhesion, ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 0,04813074 0,08949127 ! pathogenesis GO:0009405 13 10 0,000 0,04813074 0,08941898 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,04813074 0,08934681 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,04813074 0,08927476 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 0,04813074 0,08920282 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 0,000 0,04813074 0,089131 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 0,04813074 0,08905929 ! melanocyte differentiation GO:0030318 15 10 0,000 0,04813074 0,0889877 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 0,04813074 0,08891622 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 0,04813074 0,08884486 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,04813074 0,08877362 ! B cell proliferation GO:0042100 14 10 0,000 0,04813074 0,08870248 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 0,04813074 0,08863146 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,04813074 0,08856056 ! forebrain cell migration GO:0021885 17 10 0,000 0,04813074 0,08848977 ! lipid digestion GO:0044241 15 10 0,000 0,04813074 0,08841909 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,04813074 0,08834852 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,04813074 0,08827807 ! UV protection GO:0009650 14 10 0,000 0,04813074 0,08820773 ! entry into host cell GO:0030260 20 10 0,000 0,04813074 0,0881375 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 16 10 0,000 0,04813074 0,08806738 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,04813074 0,08799738 ! negative regulation of ossification GO:0030279 19 10 0,000 0,04813074 0,08792748 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 0,04813074 0,0878577 ! alpha-beta T cell activation GO:0046631 16 10 0,000 0,04813074 0,08778802 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 0,04813074 0,08771846 ! regulation of organ growth GO:0046620 11 10 0,000 0,04813074 0,08764901 ! response to dsRNA GO:0043331 18 10 0,000 0,04813074 0,08757967 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 0,04813074 0,08751043 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,04813074 0,08744131 ! embryonic axis specification GO:0000578 12 10 0,000 0,04813074 0,0873723 ! regulation of B cell differentiation GO:0045577 16 10 0,000 0,04813074 0,08730339 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,04813074 0,08723459 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,04813074 0,0871659 ! cranial nerve development GO:0021545 12 10 0,000 0,04813074 0,08709732 ! fucose catabolic process GO:0019317 16 10 0,000 0,04813074 0,08702885 GO:0042355|L-fucose catabolic process, ! DNA methylation GO:0006306 15 10 0,000 0,04813074 0,08696049 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 18 10 0,000 0,04813074 0,08689223 ! protein sumoylation GO:0016925 12 10 0,000 0,04813074 0,08682408 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 0,04813074 0,08675603 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,04813074 0,0866881 ! zymogen activation GO:0031638 14 10 0,000 0,04813074 0,08662027 ! salivary gland development GO:0007431 22 10 0,000 0,04813074 0,08655254 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,04813074 0,08648492 ! glutathione biosynthetic process GO:0006750 11 10 0,000 0,04813074 0,08641741 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,04813074 0,08635 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 0,04813074 0,0862827 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 0,04813074 0,0862155 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,04813074 0,0861484 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 0,04813074 0,08608141 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 0,04813074 0,08601453 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 0,000 0,04813074 0,08594775 GO:0043470|regulation of carbohydrate catabolic process, ! positive regulation of JNK cascade GO:0046330 14 10 0,000 0,04813074 0,08588107 ! detection of bacterium GO:0016045 10 10 0,000 0,04813074 0,0858145 ! embryonic gut development GO:0048566 11 10 0,000 0,04813074 0,08574802 ! activation of innate immune response GO:0002218 10 10 0,000 0,04813074 0,08568166 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 21 10 0,000 0,04813074 0,08561539 ! developmental induction GO:0031128 13 10 0,000 0,04813074 0,08554923 GO:0045168|cell-cell signaling involved in cell fate specification, ! regulation of synapse structure and activity GO:0050803 13 10 0,000 0,04813074 0,08548317 ! negative regulation of immune effector process GO:0002698 16 10 0,000 0,04813074 0,08541721 ! negative regulation of transport GO:0051051 116 73 1,000 0,05020113 0,08902282 ! regulation of blood pressure GO:0008217 107 73 1,000 0,05020113 0,08895424 ! digestion GO:0007586 97 74 1,000 0,05143466 0,09106983 ! protein import into nucleus GO:0006606 118 74 1,000 0,05143466 0,09099978 ! response to inorganic substance GO:0010035 115 75 1,000 0,05267905 0,09312976 ! regulation of ligase activity GO:0051340 114 75 1,000 0,05267905 0,09305823 ! nuclear import GO:0051170 121 75 1,000 0,05267905 0,09298681 ! rRNA transcription GO:0009303 17 11 0,000 0,05281599 0,09315704 ! respiratory burst GO:0045730 14 11 0,000 0,05281599 0,09308566 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 0,05281599 0,09301438 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 0,05281599 0,09294322 ! virus-host interaction GO:0019048 17 11 0,000 0,05281599 0,09287216 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 0,000 0,05281599 0,09280121 ! double-strand break repair via homologous recombination GO:0000724 16 11 0,000 0,05281599 0,09273037 GO:0000725|recombinational repair, ! filopodium assembly GO:0046847 19 11 0,000 0,05281599 0,09265964 ! Golgi vesicle budding GO:0048194 17 11 0,000 0,05281599 0,09258901 ! RNA polyadenylation GO:0043631 19 11 0,000 0,05281599 0,09251849 ! mating GO:0007618 14 11 0,000 0,05281599 0,09244808 ! dopamine receptor signaling pathway GO:0007212 22 11 0,000 0,05281599 0,09237778 ! T cell proliferation GO:0042098 20 11 0,000 0,05281599 0,09230759 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 0,05281599 0,0922375 ! bone resorption GO:0045453 16 11 0,000 0,05281599 0,09216751 ! regulated secretory pathway GO:0045055 14 11 0,000 0,05281599 0,09209764 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 0,05281599 0,09202787 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 0,05281599 0,0919582 ! regulation of mRNA processing GO:0050684 18 11 0,000 0,05281599 0,09188864 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 0,05281599 0,09181919 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 0,05281599 0,09174984 ! syncytium formation GO:0006949 15 11 0,000 0,05281599 0,09168059 ! plasma membrane organization GO:0007009 18 11 0,000 0,05281599 0,09161145 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,05281599 0,09154241 ! focal adhesion formation GO:0048041 24 11 0,000 0,05281599 0,09147348 ! mitotic spindle organization GO:0007052 15 11 0,000 0,05281599 0,09140465 ! cellular carbohydrate catabolic process GO:0044275 13 11 0,000 0,05281599 0,09133593 ! membrane protein proteolysis GO:0033619 18 11 0,000 0,05281599 0,09126731 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 0,05281599 0,09119879 ! adult heart development GO:0007512 11 11 0,000 0,05281599 0,09113037 ! chondrocyte differentiation GO:0002062 17 11 0,000 0,05281599 0,09106206 ! actin cytoskeleton reorganization GO:0031532 21 11 0,000 0,05281599 0,09099385 ! temperature homeostasis GO:0001659 16 11 0,000 0,05281599 0,09092574 ! L-glutamate transport GO:0015813 16 11 0,000 0,05281599 0,09085773 GO:0015800|acidic amino acid transport, ! regulation of vascular endothelial growth factor production GO:0010574 19 11 0,000 0,05281599 0,09078982 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,05281599 0,09072202 ! protein targeting to peroxisome GO:0006625 20 11 0,000 0,05281599 0,09065432 ! stem cell development GO:0048864 29 11 0,000 0,05281599 0,09058671 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 0,05281599 0,09051921 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 0,05281599 0,09045181 ! regulation of phagocytosis GO:0050764 14 11 0,000 0,05281599 0,09038451 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 0,05281599 0,09031731 ! vasoconstriction GO:0042310 15 11 0,000 0,05281599 0,09025021 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 0,05281599 0,09018321 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,05281599 0,09011631 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 0,05281599 0,09004951 ! regulation of Rho GTPase activity GO:0032319 18 11 0,000 0,05281599 0,0899828 ! ribosome assembly GO:0042255 13 11 0,000 0,05281599 0,0899162 ! nitric oxide metabolic process GO:0046209 14 11 0,000 0,05281599 0,08984969 GO:0006809|nitric oxide biosynthetic process, ! histone deacetylation GO:0016575 13 11 0,000 0,05281599 0,08978328 ! chromatin silencing GO:0006342 19 11 0,000 0,05281599 0,08971697 ! nucleosome positioning GO:0016584 13 11 0,000 0,05281599 0,08965076 ! T cell homeostasis GO:0043029 20 11 0,000 0,05281599 0,08958465 ! regulation of isotype switching GO:0045191 19 11 0,000 0,05281599 0,08951863 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 0,05281599 0,08945271 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,05281599 0,08938689 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 0,05281599 0,08932116 ! aromatic amino acid family catabolic process GO:0009074 13 11 0,000 0,05281599 0,08925553 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 0,05281599 0,08919 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,05281599 0,08912457 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 0,05281599 0,08905923 ! male genitalia development GO:0030539 13 11 0,000 0,05281599 0,08899398 ! cholesterol efflux GO:0033344 19 11 0,000 0,05281599 0,08892883 ! digestive tract morphogenesis GO:0048546 15 11 0,000 0,05281599 0,08886378 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 21 11 0,000 0,05281599 0,08879882 ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 0,05281599 0,08873395 ! negative regulation of glucose import GO:0046325 14 11 0,000 0,05281599 0,08866918 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 18 11 0,000 0,05281599 0,08860451 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,05281599 0,08853993 ! defense response to fungus GO:0050832 12 11 0,000 0,05281599 0,08847544 ! mRNA 3'-end processing GO:0031124 19 11 0,000 0,05281599 0,08841105 ! lysogeny GO:0030069 18 11 0,000 0,05281599 0,08834675 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 0,05281599 0,08828255 ! acrosome reaction GO:0007340 13 11 0,000 0,05281599 0,08821843 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 0,05281599 0,08815441 ! regulation of cell morphogenesis GO:0022604 140 76 1,000 0,05393417 0,08995548 ! cholesterol metabolic process GO:0008203 109 77 1,000 0,05519989 0,09199982 ! gland development GO:0048732 148 77 1,000 0,05519989 0,0919332 ! lactation GO:0007595 20 12 0,000 0,05747845 0,09565878 ! reproductive cellular process GO:0048610 14 12 0,000 0,05747845 0,09558962 ! tRNA modification GO:0006400 14 12 0,000 0,05747845 0,09552055 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 0,05747845 0,09545158 ! positive regulation of blood pressure GO:0045777 16 12 0,000 0,05747845 0,09538271 ! positive regulation of cellular catabolic process GO:0031331 22 12 0,000 0,05747845 0,09531394 ! 'de novo' protein folding GO:0006458 18 12 0,000 0,05747845 0,09524527 ! dicarboxylic acid transport GO:0006835 22 12 0,000 0,05747845 0,0951767 ! non-recombinational repair GO:0000726 19 12 0,000 0,05747845 0,09510823 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 0,05747845 0,09503986 ! peroxisomal transport GO:0043574 21 12 0,000 0,05747845 0,09497158 ! cytokine biosynthetic process GO:0042089 16 12 0,000 0,05747845 0,0949034 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,05747845 0,09483532 ! heart looping GO:0001947 15 12 0,000 0,05747845 0,09476734 ! palate development GO:0060021 15 12 0,000 0,05747845 0,09469946 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 0,05747845 0,09463167 ! regulation of skeletal muscle fiber development GO:0048742 20 12 0,000 0,05747845 0,09456398 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,05747845 0,09449638 ! arginine metabolic process GO:0006525 13 12 0,000 0,05747845 0,09442889 ! glycoprotein catabolic process GO:0006516 19 12 0,000 0,05747845 0,09436148 ! methionine metabolic process GO:0006555 13 12 0,000 0,05747845 0,09429418 ! tyrosine metabolic process GO:0006570 14 12 0,000 0,05747845 0,09422697 ! Golgi organization GO:0007030 18 12 0,000 0,05747845 0,09415986 ! cell-cell junction assembly GO:0007043 18 12 0,000 0,05747845 0,09409284 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 0,05747845 0,09402592 ! monoamine transport GO:0015844 13 12 0,000 0,05747845 0,09395909 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,05747845 0,09389236 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 0,000 0,05747845 0,09382572 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! neutral amino acid transport GO:0015804 19 12 0,000 0,05747845 0,09375918 ! L-amino acid transport GO:0015807 20 12 0,000 0,05747845 0,09369273 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 0,05747845 0,09362637 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,05747845 0,09356011 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 0,05747845 0,09349395 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,05747845 0,09342787 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 0,05747845 0,09336189 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 0,05747845 0,09329601 ! cerebellum development GO:0021549 13 12 0,000 0,05747845 0,09323021 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,05747845 0,09316451 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,05747845 0,0930989 ! histone methylation GO:0016571 15 12 0,000 0,05747845 0,09303338 ! autonomic nervous system development GO:0048483 23 12 0,000 0,05747845 0,09296796 ! gland morphogenesis GO:0022612 23 12 0,000 0,05747845 0,09290263 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 0,05747845 0,09283739 ! negative regulation of protein secretion GO:0050709 20 12 0,000 0,05747845 0,09277224 ! regulation of epidermis development GO:0045682 17 12 0,000 0,05747845 0,09270718 ! intestinal absorption GO:0050892 19 12 0,000 0,05747845 0,09264221 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 0,05747845 0,09257734 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,05747845 0,09251255 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 0,05747845 0,09244786 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,05747845 0,09238326 ! RNA 3'-end processing GO:0031123 20 12 0,000 0,05747845 0,09231874 ! microspike assembly GO:0030035 23 12 0,000 0,05747845 0,09225432 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 0,05747845 0,09218999 ! response to cold GO:0009409 14 12 0,000 0,05747845 0,09212574 ! T cell activation GO:0042110 134 79 1,000 0,0577626 0,0925167 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 1,000 0,05905932 0,09452779 GO:0010498|proteasomal protein catabolic process, ! protein localization in nucleus GO:0034504 133 80 1,000 0,05905932 0,09446206 ! regulation of cell cycle process GO:0010564 122 81 1,000 0,06036612 0,09648511 ! detection of stimulus GO:0051606 108 82 1,000 0,06168287 0,09852125 ! positive regulation of protein complex assembly GO:0031334 19 13 0,000 0,06211823 0,09914776 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,06211823 0,099079 ! cGMP metabolic process GO:0046068 16 13 0,000 0,06211823 0,09901034 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 17 13 0,000 0,06211823 0,09894177 ! water transport GO:0006833 17 13 0,000 0,06211823 0,0988733 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,06211823 0,09880492 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,06211823 0,09873664 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,06211823 0,09866845 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 0,06211823 0,09860036 ! organelle fusion GO:0048284 28 13 0,000 0,06211823 0,09853236 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,06211823 0,09846445 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! endocrine pancreas development GO:0031018 19 13 0,000 0,06211823 0,09839664 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 0,000 0,06211823 0,09832892 ! cell differentiation in spinal cord GO:0021515 16 13 0,000 0,06211823 0,09826129 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,06211823 0,09819376 ! response to hexose stimulus GO:0009746 19 13 0,000 0,06211823 0,09812632 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! induction of apoptosis via death domain receptors GO:0008625 15 13 0,000 0,06211823 0,09805897 ! glutamate metabolic process GO:0006536 18 13 0,000 0,06211823 0,09799171 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,06211823 0,09792455 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,06211823 0,09785748 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 0,06211823 0,0977905 ! NAD metabolic process GO:0019674 21 13 0,000 0,06211823 0,09772361 ! exocrine system development GO:0035272 27 13 0,000 0,06211823 0,09765681 ! negative regulation of mitotic cell cycle GO:0045930 23 13 0,000 0,06211823 0,09759011 ! bone mineralization GO:0030282 15 13 0,000 0,06211823 0,09752349 ! regulation of exocytosis GO:0017157 17 13 0,000 0,06211823 0,09745697 ! intermediate filament cytoskeleton organization GO:0045104 23 13 0,000 0,06211823 0,09739054 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 0,06211823 0,0973242 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,06211823 0,09725794 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 0,06211823 0,09719178 ! genitalia development GO:0048806 15 13 0,000 0,06211823 0,09712571 ! regulation of monooxygenase activity GO:0032768 26 13 0,000 0,06211823 0,09705973 ! tissue regeneration GO:0042246 21 13 0,000 0,06211823 0,09699384 ! cofactor transport GO:0051181 19 13 0,000 0,06211823 0,09692803 ! NADP metabolic process GO:0006739 18 13 0,000 0,06211823 0,09686232 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,06211823 0,09679669 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 0,06211823 0,09673116 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,06211823 0,09666571 ! gas transport GO:0015669 18 13 0,000 0,06211823 0,09660035 ! heme biosynthetic process GO:0006783 20 13 0,000 0,06211823 0,09653508 ! regulation of axon extension GO:0030516 23 13 0,000 0,06211823 0,0964699 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 0,000 0,06211823 0,0964048 ! lymphocyte homeostasis GO:0002260 24 13 0,000 0,06211823 0,0963398 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,06211823 0,09627488 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,06211823 0,09621005 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,06211823 0,0961453 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,06211823 0,09608065 ! regulation of cell adhesion GO:0030155 159 83 1,000 0,06300944 0,09739362 ! microtubule cytoskeleton organization GO:0000226 120 84 1,000 0,0643457 0,09939228 ! sterol metabolic process GO:0016125 120 84 1,000 0,0643457 0,09932558 ! transcription initiation GO:0006352 118 85 1,000 0,06569153 0,10133503 ! regulation of membrane potential GO:0042391 128 85 1,000 0,06569153 0,10126711 ! regulation of skeletal muscle tissue development GO:0048641 22 14 0,000 0,06673542 0,10280742 ! G1 phase of mitotic cell cycle GO:0000080 23 14 0,000 0,06673542 0,1027386 ! superoxide anion generation GO:0042554 18 14 0,000 0,06673542 0,10266988 ! neuron maturation GO:0042551 21 14 0,000 0,06673542 0,10260125 ! regulation of S phase GO:0033261 18 14 0,000 0,06673542 0,10253272 ! regulation of lipid biosynthetic process GO:0046890 16 14 0,000 0,06673542 0,10246427 ! myotube differentiation GO:0014902 21 14 0,000 0,06673542 0,10239591 ! heterophilic cell adhesion GO:0007157 29 14 0,000 0,06673542 0,10232765 ! inositol metabolic process GO:0006020 20 14 0,000 0,06673542 0,10225948 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,06673542 0,10219139 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,06673542 0,1021234 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,06673542 0,1020555 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,06673542 0,10198769 ! gene silencing by RNA GO:0031047 20 14 0,000 0,06673542 0,10191997 ! response to cAMP GO:0051591 19 14 0,000 0,06673542 0,10185234 ! startle response GO:0001964 21 14 0,000 0,06673542 0,1017848 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 0,000 0,06673542 0,10171735 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 0,06673542 0,10164998 ! activation of MAPKK activity GO:0000186 21 14 0,000 0,06673542 0,10158271 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,06673542 0,10151553 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 0,06673542 0,10144843 ! epidermis morphogenesis GO:0048730 29 14 0,000 0,06673542 0,10138142 ! glycine metabolic process GO:0006544 22 14 0,000 0,06673542 0,10131451 ! pituitary gland development GO:0021983 23 14 0,000 0,06673542 0,10124767 ! negative regulation of microtubule depolymerization GO:0007026 31 14 0,000 0,06673542 0,10118093 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 20 14 0,000 0,06673542 0,10111428 ! regulation of heart rate GO:0002027 23 14 0,000 0,06673542 0,10104771 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,06673542 0,10098123 ! embryo implantation GO:0007566 27 14 0,000 0,06673542 0,10091484 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 0,06673542 0,10084854 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 24 14 0,000 0,06673542 0,10078232 ! axon cargo transport GO:0008088 27 14 0,000 0,06673542 0,10071619 ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,06673542 0,10065015 ! DNA unwinding during replication GO:0006268 21 14 0,000 0,06673542 0,10058419 ! T cell differentiation in the thymus GO:0033077 27 14 0,000 0,06673542 0,10051832 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,06673542 0,10045254 ! mRNA splice site selection GO:0006376 26 14 0,000 0,06673542 0,10038684 ! regulation of T-helper 2 type immune response GO:0002828 21 14 0,000 0,06673542 0,10032123 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,06673542 0,1002557 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 0,06673542 0,10019026 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,06673542 0,1001249 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 0,06673542 0,10005963 ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 0,06673542 0,09999445 ! regulation of erythrocyte differentiation GO:0045646 27 14 0,000 0,06673542 0,09992935 ! muscle maintenance GO:0046716 19 14 0,000 0,06673542 0,09986433 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 0,06673542 0,0997994 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 0,06673542 0,09973455 ! regulation of ATPase activity GO:0043462 18 14 0,000 0,06673542 0,09966979 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,06673542 0,09960511 ! cell killing GO:0001906 20 14 0,000 0,06673542 0,09954052 ! cilium assembly GO:0042384 20 14 0,000 0,06673542 0,099476 ! peptide hormone secretion GO:0030072 23 14 0,000 0,06673542 0,09941158 ! Wnt receptor signaling pathway GO:0016055 130 87 1,000 0,06841142 0,10184224 ! anatomical structure homeostasis GO:0060249 136 88 1,000 0,06978522 0,10382018 ! regulation of T cell activation GO:0050863 128 89 1,000 0,0711681 0,10580907 ! regulation of protein ubiquitination GO:0031396 19 15 0,000 0,07133015 0,1059815 ! metencephalon development GO:0022037 19 15 0,000 0,07133015 0,10591308 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,07133015 0,10584475 ! negative regulation of hormone secretion GO:0046888 20 15 0,000 0,07133015 0,1057765 ! embryonic hindlimb morphogenesis GO:0035116 25 15 0,000 0,07133015 0,10570835 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 0,07133015 0,10564028 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,07133015 0,1055723 ! bile acid metabolic process GO:0008206 22 15 0,000 0,07133015 0,10550441 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 0,07133015 0,1054366 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 0,07133015 0,10536889 ! adult walking behavior GO:0007628 25 15 0,000 0,07133015 0,10530126 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,07133015 0,10523371 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,07133015 0,10516625 ! myoblast differentiation GO:0045445 27 15 0,000 0,07133015 0,10509888 ! centrosome cycle GO:0007098 16 15 0,000 0,07133015 0,1050316 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,07133015 0,1049644 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,07133015 0,10489729 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 0,07133015 0,10483026 ! cerebral cortex development GO:0021987 29 15 0,000 0,07133015 0,10476332 ! response to osmotic stress GO:0006970 22 15 0,000 0,07133015 0,10469646 ! vesicle coating GO:0006901 25 15 0,000 0,07133015 0,10462969 ! regulation of the force of heart contraction GO:0002026 21 15 0,000 0,07133015 0,10456301 ! DNA integration GO:0015074 22 15 0,000 0,07133015 0,1044964 ! peptide secretion GO:0002790 27 15 0,000 0,07133015 0,10442989 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,07133015 0,10436346 ! regulation of vasodilation GO:0042312 24 15 0,000 0,07133015 0,10429711 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 0,07133015 0,10423085 ! neuron recognition GO:0008038 22 15 0,000 0,07133015 0,10416467 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,07133015 0,10409858 ! positive regulation of oxidoreductase activity GO:0051353 21 15 0,000 0,07133015 0,10403257 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,07133015 0,10396664 ! biomineral formation GO:0031214 18 15 0,000 0,07133015 0,1039008 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,07133015 0,10383504 ! regulation of T-helper cell differentiation GO:0045622 23 15 0,000 0,07133015 0,10376936 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,07133015 0,10370376 ! dopamine metabolic process GO:0042417 30 15 0,000 0,07133015 0,10363825 ! organic cation transport GO:0015695 19 15 0,000 0,07133015 0,10357283 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,07133015 0,10350748 GO:0033014|tetrapyrrole biosynthetic process, ! defense response to virus GO:0051607 27 15 0,000 0,07133015 0,10344222 ! peptide hormone processing GO:0016486 19 15 0,000 0,07133015 0,10337704 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 0,000 0,07133015 0,10331194 ! leukocyte differentiation GO:0002521 143 90 1,000 0,07255995 0,10502699 ! glycerophospholipid metabolic process GO:0006650 130 92 1,000 0,07537004 0,10902584 ! protein secretion GO:0009306 27 16 0,000 0,07590253 0,1097271 ! regulation of glucose metabolic process GO:0010906 22 16 0,000 0,07590253 0,10965817 ! hormone secretion GO:0046879 25 16 0,000 0,07590253 0,10958933 ! bone remodeling GO:0046849 24 16 0,000 0,07590253 0,10952058 ! endothelial cell migration GO:0043542 22 16 0,000 0,07590253 0,10945192 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,07590253 0,10938334 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,07590253 0,10931485 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,07590253 0,10924644 ! glial cell development GO:0021782 24 16 0,000 0,07590253 0,10917812 ! patterning of blood vessels GO:0001569 24 16 0,000 0,07590253 0,10910988 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,07590253 0,10904173 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,07590253 0,10897366 ! protein polyubiquitination GO:0000209 26 16 0,000 0,07590253 0,10890568 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,07590253 0,10883779 ! cellular response to unfolded protein GO:0034620 19 16 0,000 0,07590253 0,10876997 GO:0030968|endoplasmic reticulum unfolded protein response, ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 0,07590253 0,10870225 ! regulation of protein binding GO:0043393 27 16 0,000 0,07590253 0,1086346 ! regulation of dephosphorylation GO:0035303 33 16 0,000 0,07590253 0,10856705 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 0,000 0,07590253 0,10849957 ! protein export from nucleus GO:0006611 24 16 0,000 0,07590253 0,10843218 ! negative regulation of immune response GO:0050777 28 16 0,000 0,07590253 0,10836487 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 0,000 0,07590253 0,10829765 ! DNA replication initiation GO:0006270 25 16 0,000 0,07590253 0,10823051 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,07590253 0,10816345 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 0,000 0,07590253 0,10809648 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,07590253 0,10802958 ! diencephalon development GO:0021536 25 16 0,000 0,07590253 0,10796278 ! oogenesis GO:0048477 23 16 0,000 0,07590253 0,10789605 ! neural crest cell migration GO:0001755 24 16 0,000 0,07590253 0,10782941 ! neutrophil chemotaxis GO:0030593 21 16 0,000 0,07590253 0,10776285 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,07590253 0,10769637 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 0,07590253 0,10762997 ! steroid catabolic process GO:0006706 22 16 0,000 0,07590253 0,10756365 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,07590253 0,10749742 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 0,000 0,07590253 0,10743127 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,07590253 0,1073652 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,07590253 0,10729921 ! sperm-egg recognition GO:0035036 16 16 0,000 0,07590253 0,1072333 GO:0007339|binding of sperm to zona pellucida, ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 0,07590253 0,10716747 ! nerve development GO:0021675 18 16 0,000 0,07590253 0,10710172 ! inner ear receptor cell differentiation GO:0060113 30 16 0,000 0,07590253 0,10703606 ! negative regulation of translation GO:0017148 22 16 0,000 0,07590253 0,10697047 ! regulation of cytoskeleton organization GO:0051493 154 93 1,000 0,07678805 0,10815219 ! polysaccharide metabolic process GO:0005976 129 93 1,000 0,07678805 0,108086 ! carboxylic acid transport GO:0046942 147 95 1,000 0,07964943 0,11204507 GO:0015849|organic acid transport, ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,08045264 0,1131058 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,08045264 0,1130367 ! negative regulation of defense response GO:0031348 19 17 0,000 0,08045264 0,11296769 ! positive regulation of hormone secretion GO:0046887 24 17 0,000 0,08045264 0,11289877 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 0,08045264 0,11282993 ! glycerol metabolic process GO:0006071 20 17 0,000 0,08045264 0,11276117 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,08045264 0,1126925 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,08045264 0,11262391 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,08045264 0,1125554 ! signal complex assembly GO:0007172 29 17 0,000 0,08045264 0,11248698 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,08045264 0,11241864 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 0,000 0,08045264 0,11235038 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,08045264 0,11228221 ! memory GO:0007613 25 17 0,000 0,08045264 0,11221412 ! keratinization GO:0031424 17 17 0,000 0,08045264 0,11214611 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,08045264 0,11207818 ! retinoid metabolic process GO:0001523 22 17 0,000 0,08045264 0,11201034 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 24 17 0,000 0,08045264 0,11194258 ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,08045264 0,1118749 ! DNA duplex unwinding GO:0032508 25 17 0,000 0,08045264 0,1118073 GO:0032392|DNA geometric change, ! vacuolar transport GO:0007034 24 17 0,000 0,08045264 0,11173978 ! cell-substrate junction assembly GO:0007044 39 17 0,000 0,08045264 0,11167235 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 0,000 0,08045264 0,111605 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,08045264 0,11153772 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,08045264 0,11147053 ! membrane budding GO:0006900 29 17 0,000 0,08045264 0,11140342 ! heme metabolic process GO:0042168 27 17 0,000 0,08045264 0,11133639 ! negative regulation of protein catabolic process GO:0042177 26 17 0,000 0,08045264 0,11126944 ! body fluid secretion GO:0007589 27 17 0,000 0,08045264 0,11120257 ! stem cell differentiation GO:0048863 36 17 0,000 0,08045264 0,11113579 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,08045264 0,11106908 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,08045264 0,11100245 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,08045264 0,1109359 ! sensory perception of pain GO:0019233 23 17 0,000 0,08045264 0,11086943 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,08045264 0,11080304 GO:0002712|regulation of B cell mediated immunity, ! synaptogenesis GO:0007416 24 17 0,000 0,08045264 0,11073673 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,08045264 0,1106705 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,08045264 0,11060435 ! regulation of immunoglobulin production GO:0002637 25 17 0,000 0,08045264 0,11053828 ! aromatic compound catabolic process GO:0019439 22 17 0,000 0,08045264 0,11047229 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,08045264 0,11040637 ! negative regulation of coagulation GO:0050819 23 17 0,000 0,08045264 0,11034054 ! regulation of response to external stimulus GO:0032101 139 96 1,000 0,08109256 0,1111519 ! in utero embryonic development GO:0001701 147 96 1,000 0,08109256 0,1110857 ! response to light stimulus GO:0009416 153 96 1,000 0,08109256 0,11101958 ! positive regulation of DNA replication GO:0045740 29 18 0,000 0,08498062 0,1162733 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 0,000 0,08498062 0,11620418 ! positive regulation of translation GO:0045727 28 18 0,000 0,08498062 0,11613513 ! positive regulation of anti-apoptosis GO:0045768 29 18 0,000 0,08498062 0,11606617 ! positive regulation of angiogenesis GO:0045766 35 18 0,000 0,08498062 0,11599728 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,08498062 0,11592848 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 0,08498062 0,11585977 ! cAMP metabolic process GO:0046058 33 18 0,000 0,08498062 0,11579113 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,08498062 0,11572257 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,08498062 0,1156541 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 0,08498062 0,1155857 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,08498062 0,11551739 GO:0050886|endocrine process, ! mechanoreceptor differentiation GO:0042490 32 18 0,000 0,08498062 0,11544916 ! pancreas development GO:0031016 26 18 0,000 0,08498062 0,11538101 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,08498062 0,11531293 ! glutamine metabolic process GO:0006541 23 18 0,000 0,08498062 0,11524494 ! pigmentation during development GO:0048066 31 18 0,000 0,08498062 0,11517703 ! central nervous system neuron development GO:0021954 30 18 0,000 0,08498062 0,1151092 ! positive regulation of cytoskeleton organization GO:0051495 33 18 0,000 0,08498062 0,11504145 ! fucose metabolic process GO:0006004 26 18 0,000 0,08498062 0,11497378 ! response to fungus GO:0009620 19 18 0,000 0,08498062 0,11490619 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 0,000 0,08498062 0,11483867 ! heart process GO:0003015 27 18 0,000 0,08498062 0,11477124 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,08498062 0,11470389 GO:0006692|prostanoid metabolic process, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,08498062 0,11463661 ! visual learning GO:0008542 35 18 0,000 0,08498062 0,11456942 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,08498062 0,1145023 ! detection of chemical stimulus GO:0009593 26 18 0,000 0,08498062 0,11443526 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,08498062 0,1143683 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,08498062 0,11430142 ! vitamin transport GO:0051180 24 18 0,000 0,08498062 0,11423461 ! hormone transport GO:0009914 27 18 0,000 0,08498062 0,11416789 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,08498062 0,11410124 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,08498062 0,11403467 ! cell-cell recognition GO:0009988 20 18 0,000 0,08498062 0,11396818 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,08498062 0,11390176 ! estrogen receptor signaling pathway GO:0030520 30 18 0,000 0,08498062 0,11383542 ! regulation of glucose import GO:0046324 21 18 0,000 0,08498062 0,11376916 GO:0010827|regulation of glucose transport, ! gut development GO:0048565 26 18 0,000 0,08498062 0,11370298 ! calcium ion transport GO:0006816 167 99 1,000 0,08547038 0,11429179 ! extracellular structure organization GO:0043062 156 99 1,000 0,08547038 0,11422538 ! protein import GO:0017038 156 99 1,000 0,08547038 0,11415905 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 1,000 0,08547038 0,11409279 ! divalent metal ion transport GO:0070838 171 100 1,000 0,08694542 0,11599448 ! protein localization in organelle GO:0033365 161 100 1,000 0,08694542 0,11592723 ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,08948656 0,11924628 ! positive regulation of protein catabolic process GO:0045732 23 19 0,000 0,08948656 0,11917723 ! positive regulation of fibroblast proliferation GO:0048146 27 19 0,000 0,08948656 0,11910826 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,08948656 0,11903937 ! reciprocal meiotic recombination GO:0007131 31 19 0,000 0,08948656 0,11897056 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 0,000 0,08948656 0,11890184 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 0,000 0,08948656 0,11883319 ! regulation of carbohydrate metabolic process GO:0006109 28 19 0,000 0,08948656 0,11876461 GO:0010675|regulation of cellular carbohydrate metabolic process, ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,08948656 0,11869612 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,08948656 0,11862771 ! regeneration GO:0031099 32 19 0,000 0,08948656 0,11855938 ! calcium-independent cell-cell adhesion GO:0016338 21 19 0,000 0,08948656 0,11849112 ! sensory perception of taste GO:0050909 23 19 0,000 0,08948656 0,11842294 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 0,000 0,08948656 0,11835485 ! smooth muscle contraction GO:0006939 36 19 0,000 0,08948656 0,11828683 ! peroxisome organization GO:0007031 29 19 0,000 0,08948656 0,11821888 ! digestive system process GO:0022600 30 19 0,000 0,08948656 0,11815102 ! cellular response to reactive oxygen species GO:0034614 27 19 0,000 0,08948656 0,11808323 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,08948656 0,11801553 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,08948656 0,1179479 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,08948656 0,11788034 ! sex determination GO:0007530 29 19 0,000 0,08948656 0,11781287 ! response to lipopolysaccharide GO:0032496 26 19 0,000 0,08948656 0,11774547 ! renal system process GO:0003014 35 19 0,000 0,08948656 0,11767815 ! vasodilation GO:0042311 33 19 0,000 0,08948656 0,1176109 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,08948656 0,11754373 ! regulation of fatty acid metabolic process GO:0019217 28 19 0,000 0,08948656 0,11747664 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,08948656 0,11740963 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,08948656 0,11734269 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,08948656 0,11727583 ! sarcomere organization GO:0045214 23 19 0,000 0,08948656 0,11720904 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,08948656 0,11714233 ! aromatic amino acid family metabolic process GO:0009072 24 19 0,000 0,08948656 0,1170757 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,08948656 0,11700914 GO:0043450|alkene biosynthetic process, ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 0,08948656 0,11694266 ! embryonic organ morphogenesis GO:0048562 23 19 0,000 0,08948656 0,11687625 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 0,08948656 0,11680992 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 0,000 0,08948656 0,11674366 ! protein stabilization GO:0050821 26 19 0,000 0,08948656 0,11667748 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,09397056 0,12245455 ! iron ion transport GO:0006826 37 20 0,000 0,09397056 0,12238521 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,09397056 0,12231595 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,09397056 0,12224677 GO:0006044|N-acetylglucosamine metabolic process, ! microtubule-based transport GO:0010970 37 20 0,000 0,09397056 0,12217766 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,09397056 0,12210864 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,09397056 0,12203969 ! spinal cord development GO:0021510 31 20 0,000 0,09397056 0,12197082 ! response to ethanol GO:0045471 37 20 0,000 0,09397056 0,12190202 ! multicellular organismal response to stress GO:0033555 32 20 0,000 0,09397056 0,12183331 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 0,000 0,09397056 0,12176467 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,09397056 0,12169611 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,09397056 0,12162762 ! chromosome condensation GO:0030261 31 20 0,000 0,09397056 0,12155922 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,09397056 0,12149089 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,09397056 0,12142263 ! regulation of ARF GTPase activity GO:0032312 31 20 0,000 0,09397056 0,12135446 ! DNA modification GO:0006304 28 20 0,000 0,09397056 0,12128636 ! collagen fibril organization GO:0030199 45 20 0,000 0,09397056 0,12121833 ! positive regulation of inflammatory response GO:0050729 30 20 0,000 0,09397056 0,12115038 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,09397056 0,12108251 ! positive regulation of B cell activation GO:0050871 31 20 0,000 0,09397056 0,12101472 ! collagen catabolic process GO:0030574 25 20 0,000 0,09397056 0,120947 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,09397056 0,12087935 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,09397056 0,12081179 ! alditol metabolic process GO:0019400 24 20 0,000 0,09397056 0,12074429 ! actin filament-based movement GO:0030048 34 20 0,000 0,09397056 0,12067688 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 0,000 0,09843274 0,12633666 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 0,000 0,09843274 0,1262662 GO:0016444|somatic cell DNA recombination, ! regulation of cell killing GO:0031341 34 21 0,000 0,09843274 0,12619582 ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 0,09843274 0,12612551 ! G2/M transition of mitotic cell cycle GO:0000086 33 21 0,000 0,09843274 0,12605529 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,09843274 0,12598514 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,09843274 0,12591507 GO:0009799|determination of symmetry, ! gluconeogenesis GO:0006094 25 21 0,000 0,09843274 0,12584508 ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,09843274 0,12577516 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,09843274 0,12570533 ! vesicle docking GO:0048278 27 21 0,000 0,09843274 0,12563557 ! phototransduction GO:0007602 25 21 0,000 0,09843274 0,12556589 ! visual behavior GO:0007632 39 21 0,000 0,09843274 0,12549628 ! regulation of DNA recombination GO:0000018 40 21 0,000 0,09843274 0,12542675 ! ovarian follicle development GO:0001541 30 21 0,000 0,09843274 0,1253573 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,09843274 0,12528793 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,09843274 0,12521864 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,09843274 0,12514942 ! regulation of insulin secretion GO:0050796 26 21 0,000 0,09843274 0,12508027 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 0,000 0,09843274 0,12501121 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 0,000 0,09843274 0,12494221 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 0,09843274 0,1248733 GO:0060415|muscle tissue morphogenesis, ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,09843274 0,12480446 ! leukotriene metabolic process GO:0006691 28 21 0,000 0,09843274 0,1247357 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,09843274 0,12466701 ! immunoglobulin production GO:0002377 33 21 0,000 0,09843274 0,1245984 GO:0002440|production of molecular mediator of immune response, ! platelet activation GO:0030168 28 21 0,000 0,09843274 0,12452986 ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,09843274 0,1244614 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,09843274 0,12439302 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,09843274 0,12432471 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,09843274 0,12425647 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,09843274 0,12418831 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,09843274 0,12412023 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,09843274 0,12405222 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,09843274 0,12398428 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,09843274 0,12391642 ! acetyl-CoA catabolic process GO:0046356 31 21 0,000 0,09843274 0,12384863 GO:0006099|tricarboxylic acid cycle, ! regulation of multi-organism process GO:0043900 32 21 0,000 0,09843274 0,12378091 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 0,000 0,10287319 0,12929417 ! regulation of anti-apoptosis GO:0045767 36 22 0,000 0,10287319 0,12922356 ! viral genome replication GO:0019079 29 22 0,000 0,10287319 0,12915302 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,10287319 0,12908256 ! spliceosomal snRNP biogenesis GO:0000387 28 22 0,000 0,10287319 0,12901218 ! leukocyte adhesion GO:0007159 38 22 0,000 0,10287319 0,12894187 ! molting cycle process GO:0022404 40 22 0,000 0,10287319 0,12887164 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! dicarboxylic acid metabolic process GO:0043648 33 22 0,000 0,10287319 0,12880149 ! glutamate signaling pathway GO:0007215 34 22 0,000 0,10287319 0,12873141 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,10287319 0,12866141 ! microtubule organizing center organization GO:0031023 28 22 0,000 0,10287319 0,12859149 GO:0051297|centrosome organization, ! regulation of cell-matrix adhesion GO:0001952 51 22 0,000 0,10287319 0,12852164 GO:0010810|regulation of cell-substrate adhesion, ! regulation of smooth muscle contraction GO:0006940 36 22 0,000 0,10287319 0,12845187 ! lysosome organization GO:0007040 37 22 0,000 0,10287319 0,12838217 ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,10287319 0,12831255 GO:0051693|actin filament capping, ! coenzyme catabolic process GO:0009109 33 22 0,000 0,10287319 0,128243 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,10287319 0,12817353 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,10287319 0,12810414 ! membrane depolarization GO:0051899 35 22 0,000 0,10287319 0,12803482 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,10287319 0,12796557 ! leukocyte homeostasis GO:0001776 33 22 0,000 0,10287319 0,1278964 ! regulation of blood coagulation GO:0030193 34 22 0,000 0,10287319 0,1278273 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,10287319 0,12775828 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,10287319 0,12768934 ! blastocyst development GO:0001824 37 22 0,000 0,10287319 0,12762046 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 0,000 0,10729203 0,13303055 ! neuron fate commitment GO:0048663 32 23 0,000 0,10729203 0,13295887 ! embryonic pattern specification GO:0009880 31 23 0,000 0,10729203 0,13288727 ! acetyl-CoA metabolic process GO:0006084 33 23 0,000 0,10729203 0,13281575 ! vesicle targeting GO:0006903 32 23 0,000 0,10729203 0,13274431 ! response to corticosteroid stimulus GO:0031960 36 23 0,000 0,10729203 0,13267294 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 0,000 0,10729203 0,13260165 ! osteoblast differentiation GO:0001649 40 23 0,000 0,10729203 0,13253043 ! regulation of viral reproduction GO:0050792 32 23 0,000 0,10729203 0,13245929 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,10729203 0,13238823 ! interaction with host GO:0051701 37 23 0,000 0,10729203 0,13231725 ! lymphocyte proliferation GO:0046651 36 23 0,000 0,10729203 0,13224634 ! cellular response to oxidative stress GO:0034599 33 23 0,000 0,10729203 0,1321755 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,10729203 0,13210475 ! negative regulation of phosphorylation GO:0042326 41 23 0,000 0,10729203 0,13203406 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,10729203 0,13196346 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,10729203 0,13189293 ! cell fate determination GO:0001709 45 23 0,000 0,10729203 0,13182247 ! pentose metabolic process GO:0019321 31 23 0,000 0,10729203 0,13175209 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,10729203 0,13168179 ! spermatid development GO:0007286 33 23 0,000 0,10729203 0,13161155 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,10729203 0,1315414 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,10729203 0,13147132 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,10729203 0,13140131 ! somatic diversification of immune receptors GO:0002200 35 23 0,000 0,10729203 0,13133138 ! telomere organization GO:0032200 32 23 0,000 0,10729203 0,13126152 GO:0000723|telomere maintenance, ! negative regulation of catabolic process GO:0009895 34 23 0,000 0,10729203 0,13119174 ! response to molecule of bacterial origin GO:0002237 30 23 0,000 0,10729203 0,13112203 ! regulation of amine transport GO:0051952 38 23 0,000 0,10729203 0,1310524 ! liver development GO:0001889 40 23 0,000 0,10729203 0,13098284 ! positive regulation of cell projection organization GO:0031346 39 24 0,000 0,11168935 0,13627879 ! regulation of cellular catabolic process GO:0031329 36 24 0,000 0,11168935 0,13620653 ! initiation of viral infection GO:0019059 42 24 0,000 0,11168935 0,13613435 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,11168935 0,13606224 ! pyruvate metabolic process GO:0006090 29 24 0,000 0,11168935 0,13599021 ! superoxide metabolic process GO:0006801 32 24 0,000 0,11168935 0,13591826 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,11168935 0,13584638 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! fat cell differentiation GO:0045444 37 24 0,000 0,11168935 0,13577458 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,11168935 0,13570286 ! sperm motility GO:0030317 27 24 0,000 0,11168935 0,13563121 ! vacuole organization GO:0007033 39 24 0,000 0,11168935 0,13555964 ! receptor metabolic process GO:0043112 37 24 0,000 0,11168935 0,13548814 ! neural crest cell development GO:0014032 39 24 0,000 0,11168935 0,13541672 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 38 24 0,000 0,11168935 0,13534537 ! regulation of alpha-beta T cell activation GO:0046634 35 24 0,000 0,11168935 0,1352741 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,11168935 0,1352029 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of oxidoreductase activity GO:0051341 39 24 0,000 0,11168935 0,13513178 ! glutathione metabolic process GO:0006749 29 24 0,000 0,11168935 0,13506073 ! neurotransmitter secretion GO:0007269 32 24 0,000 0,11168935 0,13498976 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,11606527 0,14020489 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,11606527 0,14013129 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,11606527 0,14005777 GO:0006479|protein amino acid methylation, ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,11606527 0,13998433 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,11606527 0,13991096 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 0,000 0,11606527 0,13983767 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 34 25 0,000 0,11606527 0,13976446 ! peptide transport GO:0015833 43 25 0,000 0,11606527 0,13969132 ! male gonad development GO:0008584 33 25 0,000 0,11606527 0,13961826 ! regulation of peptide secretion GO:0002791 34 25 0,000 0,11606527 0,13954528 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,11606527 0,13947237 ! phospholipid transport GO:0015914 35 25 0,000 0,11606527 0,13939954 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,11606527 0,13932678 ! positive regulation of MAPKKK cascade GO:0043410 36 25 0,000 0,11606527 0,1392541 ! detection of light stimulus GO:0009583 30 25 0,000 0,11606527 0,1391815 ! peptidyl-tyrosine modification GO:0018212 37 25 0,000 0,11606527 0,13910897 ! leukocyte proliferation GO:0070661 39 25 0,000 0,11606527 0,13903652 GO:0032943|mononuclear cell proliferation, ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,12041988 0,14417788 ! translational initiation GO:0006413 43 26 0,000 0,12041988 0,14410287 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 0,000 0,12041988 0,14402793 ! circadian rhythm GO:0007623 42 26 0,000 0,12041988 0,14395307 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,12041988 0,14387829 ! post-embryonic development GO:0009791 42 26 0,000 0,12041988 0,14380359 ! negative regulation of protein modification process GO:0031400 50 26 0,000 0,12041988 0,14372896 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,12041988 0,14365442 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,12041988 0,14357994 ! negative regulation of protein kinase cascade GO:0010741 51 26 0,000 0,12041988 0,14350555 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 0,000 0,12041988 0,14343123 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,12041988 0,14335699 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,12041988 0,14328283 ! negative regulation of protein polymerization GO:0032272 38 26 0,000 0,12041988 0,14320874 ! regulation of coagulation GO:0050818 39 26 0,000 0,12041988 0,14313474 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,12475328 0,14820896 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,12475328 0,14813244 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,12475328 0,14805601 ! membrane docking GO:0022406 39 27 0,000 0,12475328 0,14797965 ! inner ear morphogenesis GO:0042472 35 27 0,000 0,12475328 0,14790337 ! catechol metabolic process GO:0009712 43 27 0,000 0,12475328 0,14782717 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,12475328 0,14775105 ! acute-phase response GO:0006953 42 27 0,000 0,12475328 0,14767501 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,12475328 0,14759904 ! myofibril assembly GO:0030239 36 27 0,000 0,12475328 0,14752316 GO:0055002|striated muscle cell development, ! respiratory gaseous exchange GO:0007585 47 27 0,000 0,12475328 0,14744735 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 0,000 0,12475328 0,14737162 ! natural killer cell activation GO:0030101 35 27 0,000 0,12475328 0,14729597 ! lipid oxidation GO:0034440 38 27 0,000 0,12475328 0,14722039 GO:0019395|fatty acid oxidation, ! cofactor catabolic process GO:0051187 45 27 0,000 0,12475328 0,14714489 ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,12475328 0,14706947 ! negative regulation of transcription regulator activity GO:0090048 47 27 0,000 0,12475328 0,14699413 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of neuron apoptosis GO:0043524 42 27 0,000 0,12475328 0,14691886 ! gene silencing GO:0016458 41 27 0,000 0,12475328 0,14684367 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 0,000 0,12906558 0,15184186 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,12906558 0,15176423 ! phenol metabolic process GO:0018958 44 28 0,000 0,12906558 0,15168668 ! negative regulation of protein complex assembly GO:0031333 42 28 0,000 0,12906558 0,15160921 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,12906558 0,15153182 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,12906558 0,15145451 ! cell junction assembly GO:0034329 56 28 0,000 0,12906558 0,15137727 ! positive regulation of endocytosis GO:0045807 33 28 0,000 0,12906558 0,15130012 ! cholesterol homeostasis GO:0042632 46 28 0,000 0,12906558 0,15122304 GO:0055092|sterol homeostasis, ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,12906558 0,15114605 ! triglyceride metabolic process GO:0006641 34 28 0,000 0,12906558 0,15106913 ! response to organic cyclic substance GO:0014070 47 28 0,000 0,12906558 0,15099229 ! positive regulation of T cell differentiation GO:0045582 39 28 0,000 0,12906558 0,15091552 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,12906558 0,15083884 ! positive regulation of multicellular organism growth GO:0040018 38 28 0,000 0,12906558 0,15076223 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,12906558 0,1506857 ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,12906558 0,15060925 ! myeloid leukocyte activation GO:0002274 39 28 0,000 0,12906558 0,15053288 ! positive regulation of catabolic process GO:0009896 40 28 0,000 0,12906558 0,15045658 ! placenta development GO:0001890 37 28 0,000 0,12906558 0,15038036 ! regulation of B cell activation GO:0050864 42 28 0,000 0,12906558 0,15030422 ! response to hydrogen peroxide GO:0042542 42 29 0,000 0,13335688 0,15522309 ! regulation of innate immune response GO:0045088 38 29 0,000 0,13335688 0,15514458 ! ovulation cycle process GO:0022602 41 29 0,000 0,13335688 0,15506614 ! positive regulation of T cell proliferation GO:0042102 44 29 0,000 0,13335688 0,15498778 ! protein targeting to membrane GO:0006612 53 29 0,000 0,13335688 0,15490951 ! regulation of axonogenesis GO:0050770 51 29 0,000 0,13335688 0,15483131 ! mismatch repair GO:0006298 34 29 0,000 0,13335688 0,15475319 ! muscle cell development GO:0055001 38 29 0,000 0,13335688 0,15467515 ! hexose biosynthetic process GO:0019319 35 29 0,000 0,13335688 0,15459719 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,13335688 0,15451931 ! tissue homeostasis GO:0001894 42 29 0,000 0,13335688 0,1544415 GO:0048871|multicellular organismal homeostasis, ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 0,000 0,13762728 0,15930687 ! collagen metabolic process GO:0032963 40 30 0,000 0,13762728 0,15922673 ! organic anion transport GO:0015711 51 30 0,000 0,13762728 0,15914668 ! cholesterol transport GO:0030301 46 30 0,000 0,13762728 0,15906671 GO:0015918|sterol transport, ! embryonic skeletal system morphogenesis GO:0048704 42 30 0,000 0,13762728 0,15898681 ! spliceosome assembly GO:0000245 49 30 0,000 0,13762728 0,158907 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,13762728 0,15882727 ! ceramide metabolic process GO:0006672 43 30 0,000 0,13762728 0,15874762 ! ovulation cycle GO:0042698 43 30 0,000 0,13762728 0,15866804 ! hindbrain development GO:0030902 45 30 0,000 0,13762728 0,15858855 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,13762728 0,15850914 ! adult locomotory behavior GO:0008344 47 30 0,000 0,13762728 0,1584298 ! regulation of microtubule-based process GO:0032886 58 30 0,000 0,13762728 0,15835055 ! response to heat GO:0009408 41 30 0,000 0,13762728 0,15827137 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,13762728 0,15819228 ! negative regulation of secretion GO:0051048 49 31 0,000 0,14187688 0,16299542 ! glial cell differentiation GO:0010001 55 31 0,000 0,14187688 0,16291404 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 0,000 0,14187688 0,16283275 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,14187688 0,16275154 ! xenobiotic metabolic process GO:0006805 44 31 0,000 0,14187688 0,1626704 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,14187688 0,16258935 ! cell fate specification GO:0001708 37 31 0,000 0,14187688 0,16250838 ! leukocyte chemotaxis GO:0030595 43 31 0,000 0,14187688 0,16242749 GO:0060326|cell chemotaxis, ! biogenic amine biosynthetic process GO:0042401 44 31 0,000 0,14187688 0,16234668 ! RNA modification GO:0009451 40 31 0,000 0,14187688 0,16226595 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 0,000 0,14610579 0,16701954 ! regulation of synaptic plasticity GO:0048167 52 32 0,000 0,14610579 0,16693657 ! regulation of ARF protein signal transduction GO:0032012 51 32 0,000 0,14610579 0,16685368 ! neutral lipid metabolic process GO:0006638 41 32 0,000 0,14610579 0,16677087 GO:0006639|acylglycerol metabolic process, ! regulation of protein stability GO:0031647 48 32 0,000 0,14610579 0,16668815 ! calcium-mediated signaling GO:0019722 50 32 0,000 0,14610579 0,16660551 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 0,000 0,14610579 0,16652295 ! cytokine production GO:0001816 44 32 0,000 0,14610579 0,16644047 ! monosaccharide biosynthetic process GO:0046364 38 32 0,000 0,14610579 0,16635807 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 0,000 0,14610579 0,16627576 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 0,000 0,15031409 0,17098042 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! RNA export from nucleus GO:0006405 44 33 0,000 0,15031409 0,1708959 ! positive regulation of DNA metabolic process GO:0051054 54 33 0,000 0,15031409 0,17081147 ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,15031409 0,17072711 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,15031409 0,17064285 ! negative regulation of cell adhesion GO:0007162 67 33 0,000 0,15031409 0,17055866 ! actomyosin structure organization GO:0031032 43 33 0,000 0,15031409 0,17047456 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,15031409 0,17039054 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,15031409 0,1703066 ! carbohydrate homeostasis GO:0033500 39 33 0,000 0,15031409 0,17022275 GO:0042593|glucose homeostasis, ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 0,000 0,15031409 0,17013898 ! female gonad development GO:0008585 49 33 0,000 0,15031409 0,17005529 ! lipid homeostasis GO:0055088 55 33 0,000 0,15031409 0,16997169 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,15031409 0,16988816 ! regulation of proteolysis GO:0030162 50 33 0,000 0,15031409 0,16980472 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,15031409 0,16972136 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,15031409 0,16963808 ! mRNA catabolic process GO:0006402 48 34 0,000 0,15450189 0,17427874 ! regulation of neuron projection development GO:0010975 63 34 0,000 0,15450189 0,17419331 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 0,000 0,15450189 0,17410796 ! establishment or maintenance of cell polarity GO:0007163 61 34 0,000 0,15450189 0,1740227 ! development of primary male sexual characteristics GO:0046546 44 34 0,000 0,15450189 0,17393752 ! glycerol ether metabolic process GO:0006662 44 34 0,000 0,15450189 0,17385242 ! female gamete generation GO:0007292 43 34 0,000 0,15450189 0,17376741 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,15450189 0,17368248 ! polyol metabolic process GO:0019751 44 34 0,000 0,15450189 0,17359763 ! aerobic respiration GO:0009060 47 34 0,000 0,15450189 0,17351287 ! embryonic organ development GO:0048568 45 34 0,000 0,15450189 0,17342819 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 0,000 0,15450189 0,17334359 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,1586693 0,17793241 ! Notch signaling pathway GO:0007219 56 35 0,000 0,1586693 0,1778457 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,1586693 0,17775908 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,1586693 0,17767253 GO:0032313|regulation of Rab GTPase activity, ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,1586693 0,17758607 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,1586693 0,1774997 GO:0015986|ATP synthesis coupled proton transport, ! Rho protein signal transduction GO:0007266 51 35 0,000 0,1586693 0,17741341 ! pigment metabolic process GO:0042440 61 35 0,000 0,1586693 0,1773272 ! positive regulation of leukocyte proliferation GO:0070665 50 35 0,000 0,1586693 0,17724108 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! response to reactive oxygen species GO:0000302 55 36 0,000 0,1628164 0,1817853 ! regulation of hormone secretion GO:0046883 48 36 0,000 0,1628164 0,18169709 ! cellular amide metabolic process GO:0043603 52 36 0,000 0,1628164 0,18160898 ! organic ether metabolic process GO:0018904 46 36 0,000 0,1628164 0,18152095 ! development of primary female sexual characteristics GO:0046545 52 36 0,000 0,1628164 0,181433 GO:0046660|female sex differentiation, ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,1628164 0,18134514 ! response to xenobiotic stimulus GO:0009410 50 36 0,000 0,1628164 0,18125736 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 0,000 0,16694329 0,18576176 ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,16694329 0,18567194 ! ion transmembrane transport GO:0034220 56 37 0,000 0,16694329 0,1855822 ! ribonucleoside metabolic process GO:0009119 48 37 0,000 0,16694329 0,18549254 ! regulation of protein secretion GO:0050708 51 37 0,000 0,16694329 0,18540298 ! amino acid activation GO:0043038 52 37 0,000 0,16694329 0,1853135 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,16694329 0,1852241 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 0,000 0,17105008 0,18968909 ! gliogenesis GO:0042063 71 38 0,000 0,17105008 0,18959767 ! alcohol biosynthetic process GO:0046165 45 38 0,000 0,17105008 0,18950635 ! phagocytosis GO:0006909 60 38 0,000 0,17105008 0,18941511 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 0,000 0,17513685 0,19384733 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,17513685 0,19375409 ! multicellular organismal metabolic process GO:0044236 50 39 0,000 0,17513685 0,19366094 ! male sex differentiation GO:0046661 53 39 0,000 0,17513685 0,19356788 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 0,000 0,17513685 0,19347491 ! chromatin remodeling GO:0006338 68 39 0,000 0,17513685 0,19338202 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,17513685 0,19328923 ! developmental growth GO:0048589 62 39 0,000 0,17513685 0,19319652 ! cell growth GO:0016049 61 39 0,000 0,17513685 0,19310391 ! regulation of actin filament polymerization GO:0030833 59 40 0,000 0,17920371 0,19749331 ! regulation of tube size GO:0035150 60 40 0,000 0,17920371 0,19739872 GO:0050880|regulation of blood vessel size, ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 0,000 0,17920371 0,19730423 ! peptide metabolic process GO:0006518 56 40 0,000 0,17920371 0,19720982 ! inner ear development GO:0048839 57 40 0,000 0,17920371 0,19711551 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,17920371 0,19702129 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! JAK-STAT cascade GO:0007259 53 40 0,000 0,17920371 0,19692715 ! epithelial cell differentiation GO:0030855 55 41 0,000 0,18325075 0,20127828 ! glucose transport GO:0015758 52 41 0,000 0,18325075 0,20118221 ! endosome transport GO:0016197 71 41 0,000 0,18325075 0,20108622 ! striated muscle contraction GO:0006941 62 41 0,000 0,18325075 0,20099033 ! regulation of leukocyte mediated immunity GO:0002703 62 41 0,000 0,18325075 0,20089453 ! biopolymer methylation GO:0043414 62 41 0,000 0,18325075 0,20079882 ! receptor-mediated endocytosis GO:0006898 76 42 0,000 0,18727807 0,20511407 ! regulation of JAK-STAT cascade GO:0046425 61 42 0,000 0,18727807 0,20501645 ! hexose transport GO:0008645 54 42 0,000 0,18727807 0,20491891 GO:0015749|monosaccharide transport, ! embryonic skeletal system development GO:0048706 56 42 0,000 0,18727807 0,20482147 ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,18727807 0,20472412 ! excretion GO:0007588 63 42 0,000 0,18727807 0,20462687 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,18727807 0,2045297 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,18727807 0,20443263 ! regulation of gene expression, epigenetic GO:0040029 72 42 0,000 0,18727807 0,20433565 ! leukocyte migration GO:0050900 60 43 0,000 0,19128576 0,20860941 ! neuromuscular process GO:0050905 79 43 0,000 0,19128576 0,20851054 ! DNA-dependent DNA replication GO:0006261 59 43 0,000 0,19128576 0,20841177 ! tRNA processing GO:0008033 49 43 0,000 0,19128576 0,20831309 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 0,000 0,19128576 0,2082145 ! methylation GO:0032259 64 43 0,000 0,19128576 0,20811601 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,19527391 0,21235461 ! regulation of cell projection organization GO:0031344 83 44 0,000 0,19527391 0,21225425 ! glycolysis GO:0006096 53 44 0,000 0,19527391 0,21215399 ! regulation of ion transport GO:0043269 57 44 0,000 0,19527391 0,21205382 ! cellular amino acid biosynthetic process GO:0008652 51 44 0,000 0,19527391 0,21195375 ! induction of apoptosis by extracellular signals GO:0008624 74 44 0,000 0,19527391 0,21185377 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 0,000 0,19527391 0,21175389 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,19527391 0,2116541 ! regulation of inflammatory response GO:0050727 60 44 0,000 0,19527391 0,2115544 ! RNA catabolic process GO:0006401 64 45 0,000 0,19924262 0,21575237 ! positive regulation of defense response GO:0031349 59 45 0,000 0,19924262 0,21565084 ! regulation of translational initiation GO:0006446 64 45 0,000 0,19924262 0,21554941 ! cell recognition GO:0008037 58 45 0,000 0,19924262 0,21544807 ! cell maturation GO:0048469 60 45 0,000 0,19924262 0,21534682 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,20319199 0,21951225 ! cell redox homeostasis GO:0045454 63 46 0,000 0,20319199 0,21940919 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,20319199 0,21930623 ! regulation of adaptive immune response GO:0002819 72 46 0,000 0,20319199 0,21920337 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,20712211 0,22333842 ! viral infectious cycle GO:0019058 71 47 0,000 0,20712211 0,22323376 ! response to estrogen stimulus GO:0043627 74 47 0,000 0,20712211 0,2231292 ! endocrine system development GO:0035270 83 47 0,000 0,20712211 0,22302474 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 0,000 0,20712211 0,22292038 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,20712211 0,22281611 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,20712211 0,22271194 ! regulation of protein polymerization GO:0032271 71 47 0,000 0,20712211 0,22260787 ! chloride transport GO:0006821 67 48 0,000 0,21103306 0,2267053 ! regulation of muscle contraction GO:0006937 69 48 0,000 0,21103306 0,22659946 ! response to temperature stimulus GO:0009266 62 48 0,000 0,21103306 0,22649372 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 0,000 0,21103306 0,22638808 ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,21103306 0,22628254 ! regulation of endocytosis GO:0030100 63 48 0,000 0,21103306 0,22617709 ! positive regulation of cytokine production GO:0001819 73 48 0,000 0,21103306 0,22607175 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,21492495 0,23013379 ! sensory perception of smell GO:0007608 61 49 0,000 0,21492495 0,2300267 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,21492495 0,22991971 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,21492495 0,22981282 ! RNA elongation GO:0006354 62 49 0,000 0,21492495 0,22970603 ! germ cell development GO:0007281 68 49 0,000 0,21492495 0,22959934 ! heterocycle catabolic process GO:0046700 72 49 0,000 0,21492495 0,22949275 ! regulation of multicellular organism growth GO:0040014 65 50 0,000 0,21879786 0,23351976 ! proton transport GO:0015992 75 50 0,000 0,21879786 0,23341145 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 0,000 0,21879786 0,23330324 ! positive regulation of secretion GO:0051047 71 51 0,000 0,22265189 0,23730275 ! hydrogen transport GO:0006818 77 51 0,000 0,22265189 0,23719284 ! activation of phospholipase C activity GO:0007202 87 51 0,000 0,22265189 0,23708303 GO:0010863|positive regulation of phospholipase C activity, ! regulation of protein catabolic process GO:0042176 77 51 0,000 0,22265189 0,23697332 ! adult behavior GO:0030534 80 51 0,000 0,22265189 0,23686371 ! transition metal ion transport GO:0000041 74 52 0,000 0,22648712 0,24083235 ! positive regulation of phospholipase activity GO:0010518 88 52 0,000 0,22648712 0,24072106 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,22648712 0,24060987 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,23030365 0,24455143 ! regulation of neurotransmitter levels GO:0001505 73 53 0,000 0,23030365 0,24443857 ! single fertilization GO:0007338 59 53 0,000 0,23030365 0,24432583 ! cell projection assembly GO:0030031 76 53 0,000 0,23030365 0,24421318 ! amino acid transport GO:0006865 84 54 0,000 0,23410156 0,24812608 ! regulation of protein complex assembly GO:0043254 81 54 0,000 0,23410156 0,24801179 ! glucose catabolic process GO:0006007 66 54 0,000 0,23410156 0,24789761 ! regulation of phospholipase activity GO:0010517 90 54 0,000 0,23410156 0,24778352 ! cytokine-mediated signaling pathway GO:0019221 76 54 0,000 0,23410156 0,24766955 ! cellular amino acid catabolic process GO:0009063 74 54 0,000 0,23410156 0,24755568 ! positive regulation of lipase activity GO:0060193 90 54 0,000 0,23410156 0,24744191 ! exocytosis GO:0006887 74 55 0,000 0,23788096 0,25132118 ! nucleoside metabolic process GO:0009116 69 55 0,000 0,23788096 0,25120579 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,23788096 0,2510905 ! negative regulation of response to stimulus GO:0048585 80 56 0,000 0,24164192 0,25494331 ! carbohydrate transport GO:0008643 74 57 0,000 0,24538453 0,25877323 ! multicellular organism reproduction GO:0032504 83 57 0,000 0,24538453 0,25865464 GO:0048609|reproductive process in a multicellular organism, ! coenzyme biosynthetic process GO:0009108 67 57 0,000 0,24538453 0,25853615 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,24538453 0,25841778 ! secondary metabolic process GO:0019748 84 57 0,000 0,24538453 0,25829951 ! gonad development GO:0008406 79 57 0,000 0,24538453 0,25818135 ! viral reproductive process GO:0022415 87 58 0,000 0,24910889 0,26198008 ! regulation of cytokine biosynthetic process GO:0042035 76 58 0,000 0,24910889 0,26186035 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 0,000 0,25281508 0,26563485 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,25281508 0,26551355 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 0,000 0,25650319 0,26926396 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 0,000 0,25650319 0,26914112 ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,25650319 0,26901839 ! regulation of heart contraction GO:0008016 91 60 0,000 0,25650319 0,26889577 ! regulation of vesicle-mediated transport GO:0060627 79 60 0,000 0,25650319 0,26877327 ! fertilization GO:0009566 68 60 0,000 0,25650319 0,26865088 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,2601733 0,27237077 ! extracellular matrix organization GO:0030198 103 61 0,000 0,2601733 0,27224686 ! negative regulation of ligase activity GO:0051352 91 61 0,000 0,2601733 0,27212305 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! amine catabolic process GO:0009310 90 62 0,000 0,26382551 0,27581758 ! neurotransmitter transport GO:0006836 81 62 0,000 0,26382551 0,27569226 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,26382551 0,27556706 ! cAMP-mediated signaling GO:0019933 97 63 0,000 0,26745989 0,27923638 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 0,000 0,26745989 0,27910969 ! viral reproduction GO:0016032 92 63 0,000 0,26745989 0,27898311 ! regulation of lipase activity GO:0060191 109 63 0,000 0,26745989 0,27885664 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 0,000 0,27107654 0,28249934 ! hexose catabolic process GO:0019320 82 64 0,000 0,27107654 0,2823714 ! reproductive structure development GO:0048608 90 65 0,000 0,27467555 0,28599084 ! defense response to bacterium GO:0042742 73 65 0,000 0,27467555 0,28586143 ! positive regulation of T cell activation GO:0050870 94 65 0,000 0,27467555 0,28573214 ! antigen processing and presentation GO:0019882 96 66 0,000 0,27825698 0,28932688 ! regulation of immune effector process GO:0002697 101 66 0,000 0,27825698 0,28919614 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,28182094 0,29276792 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,28536751 0,2963184 ! development of primary sexual characteristics GO:0045137 92 68 0,000 0,28536751 0,29618469 ! intracellular protein transmembrane transport GO:0065002 102 68 0,000 0,28536751 0,29605109 ! regulation of Ras GTPase activity GO:0032318 110 68 0,000 0,28536751 0,29591761 ! rhythmic process GO:0048511 105 68 0,000 0,28536751 0,29578426 ! inorganic anion transport GO:0015698 93 68 0,000 0,28536751 0,29565102 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,28889676 0,29917269 ! activation of protein kinase activity GO:0032147 102 69 0,000 0,28889676 0,29903805 ! amine transport GO:0015837 101 70 0,000 0,29240878 0,3025372 ! positive regulation of phosphorylation GO:0042327 102 70 0,000 0,29240878 0,30240117 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 0,000 0,29240878 0,30226526 ! regulation of catabolic process GO:0009894 106 70 0,000 0,29240878 0,30212947 ! steroid biosynthetic process GO:0006694 94 71 0,000 0,29590366 0,30560324 ! monosaccharide catabolic process GO:0046365 91 71 0,000 0,29590366 0,30546608 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 0,000 0,29938148 0,30891763 GO:0045937|positive regulation of phosphate metabolic process, ! regulation of synaptic transmission GO:0050804 109 72 0,000 0,29938148 0,3087791 ! cellular lipid catabolic process GO:0044242 105 73 0,000 0,30284232 0,31220857 ! response to steroid hormone stimulus GO:0048545 114 73 0,000 0,30284232 0,3120687 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,30628626 0,31547622 ! positive regulation of lymphocyte activation GO:0051251 108 74 0,000 0,30628626 0,315335 ! blood coagulation GO:0007596 116 75 0,000 0,30971338 0,31872071 GO:0050817|coagulation, ! cofactor biosynthetic process GO:0051188 92 75 0,000 0,30971338 0,31857817 ! amine biosynthetic process GO:0009309 97 76 0,000 0,31312377 0,32194219 ! tRNA metabolic process GO:0006399 95 76 0,000 0,31312377 0,32179834 ! response to unfolded protein GO:0006986 99 76 0,000 0,31312377 0,32165461 ! regulation of adenylate cyclase activity GO:0045761 131 77 0,000 0,31651751 0,32499565 ! sex differentiation GO:0007548 105 77 0,000 0,31651751 0,32485063 ! protein ubiquitination GO:0016567 125 77 0,000 0,31651751 0,32470574 ! one-carbon metabolic process GO:0006730 110 77 0,000 0,31651751 0,32456097 ! regulation of transmission of nerve impulse GO:0051969 116 77 0,000 0,31651751 0,32441634 ! carbohydrate biosynthetic process GO:0016051 97 77 0,000 0,31651751 0,32427183 ! positive regulation of protein modification process GO:0031401 107 78 0,000 0,31989467 0,32758581 ! nitrogen compound catabolic process GO:0044270 114 78 0,000 0,31989467 0,32744003 ! regulation of cyclase activity GO:0031279 132 78 0,000 0,31989467 0,32729437 ! regulation of cAMP biosynthetic process GO:0030817 136 79 0,000 0,32325534 0,33058572 ! cellular respiration GO:0045333 107 79 0,000 0,32325534 0,33043879 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,32325534 0,33029199 ! regulation of lyase activity GO:0051339 133 79 0,000 0,32325534 0,33014533 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,32325534 0,32999879 ! chromatin assembly GO:0031497 102 80 0,000 0,32659959 0,33326489 GO:0006334|nucleosome assembly, ! alcohol catabolic process GO:0046164 104 80 0,000 0,32659959 0,3331171 ! regulation of GTPase activity GO:0043087 129 80 0,000 0,32659959 0,33296944 ! regulation of cAMP metabolic process GO:0030814 141 81 0,000 0,32992751 0,33621323 ! hemostasis GO:0007599 125 81 0,000 0,32992751 0,33606433 ! mRNA transport GO:0051028 121 81 0,000 0,32992751 0,33591557 ! response to protein stimulus GO:0051789 111 81 0,000 0,32992751 0,33576693 ! regulation of neurological system process GO:0031644 122 81 0,000 0,32992751 0,33561843 ! vitamin metabolic process GO:0006766 103 81 0,000 0,32992751 0,33547006 ! positive regulation of cell activation GO:0050867 120 81 0,000 0,32992751 0,33532182 GO:0002696|positive regulation of leukocyte activation, ! regulation of nucleotide biosynthetic process GO:0030808 141 83 0,000 0,33653465 0,34188591 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! biogenic amine metabolic process GO:0006576 121 83 0,000 0,33653465 0,34173497 ! regulation of defense response GO:0031347 117 84 0,000 0,33981404 0,34491275 ! protein-DNA complex assembly GO:0065004 107 84 0,000 0,33981404 0,3447606 ! Golgi vesicle transport GO:0048193 138 85 0,000 0,3430774 0,347918 ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 0,000 0,34632482 0,35105645 ! nucleosome organization GO:0034728 114 87 0,000 0,34955637 0,35417606 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 0,000 0,34955637 0,3540201 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cellular defense response GO:0006968 102 87 0,000 0,34955637 0,35386429 ! female pregnancy GO:0007565 130 87 0,000 0,34955637 0,3537086 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 0,000 0,35277213 0,35680559 ! carboxylic acid catabolic process GO:0046395 122 88 0,000 0,35277213 0,35664875 GO:0016054|organic acid catabolic process, ! establishment of RNA localization GO:0051236 128 88 0,000 0,35277213 0,35649205 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! reproductive developmental process GO:0003006 127 89 0,000 0,35597218 0,35956786 ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 0,000 0,35597218 0,35941001 ! regulation of nucleotide metabolic process GO:0006140 150 89 0,000 0,35597218 0,35925231 ! protein modification by small protein conjugation GO:0032446 140 90 0,000 0,35915659 0,36230708 ! hormone metabolic process GO:0042445 121 90 0,000 0,35915659 0,36214825 ! RNA localization GO:0006403 135 91 0,000 0,36232543 0,36518339 ! ATP metabolic process GO:0046034 137 91 0,000 0,36232543 0,36502343 ! response to virus GO:0009615 122 91 0,000 0,36232543 0,36486361 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 0,000 0,36547879 0,36787799 ! DNA recombination GO:0006310 146 92 0,000 0,36547879 0,36771706 ! sulfur metabolic process GO:0006790 118 92 0,000 0,36547879 0,36755628 ! carbohydrate catabolic process GO:0016052 121 93 0,000 0,36861673 0,37055003 ! electron transport chain GO:0022900 123 94 0,000 0,37173933 0,37352576 ! response to oxidative stress GO:0006979 141 94 0,000 0,37173933 0,37336265 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 0,000 0,37793882 0,37942352 ! regulation of cellular component biogenesis GO:0044087 158 96 0,000 0,37793882 0,37925798 ! protein modification by small protein conjugation or removal GO:0070647 148 96 0,000 0,37793882 0,37909258 ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,38101585 0,38201241 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 0,000 0,38101585 0,38184595 ! regulation of translation GO:0006417 151 100 0,000 0,39015697 0,39083668 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 0,000 0,39015697 0,39066653 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 0,000 0,39015697 0,39049653 ! regulation of body fluid levels GO:0050878 154 100 0,000 0,39015697 0,39032668 ! Ras protein signal transduction GO:0007265 162 100 0,000 0,39015697 0,39015697