pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6660-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! protein amino acid autophosphorylation GO:0046777 141 60 7,000 2,672E-11 6,43E-08 ! positive regulation of cell migration GO:0030335 126 57 6,000 8,901E-10 1,071E-06 ! positive regulation of cell motion GO:0051272 146 64 6,000 2,052E-09 1,646E-06 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 6,000 2,849E-09 1,714E-06 ! positive regulation of endothelial cell migration GO:0010595 19 8 3,000 8,254E-09 3,972E-06 ! positive regulation of MAP kinase activity GO:0043406 160 93 6,000 2,891E-08 1,159E-05 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 3,000 2,742E-07 9,424E-05 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 2,000 3,643E-07 1,096E-04 ! regulation of endothelial cell migration GO:0010594 44 19 3,000 4,442E-07 1,188E-04 ! regulation of protein export from nucleus GO:0046825 10 7 2,000 1,269E-06 3,053E-04 ! insulin receptor signaling pathway GO:0008286 64 26 3,000 1,683E-06 3,681E-04 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 2,000 2,025E-06 4,06E-04 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 2,000 3,03E-06 5,608E-04 ! protein heterooligomerization GO:0051291 16 9 2,000 3,03E-06 5,208E-04 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 2,000 4,318E-06 6,927E-04 ! blood vessel remodeling GO:0001974 29 11 2,000 5,923E-06 8,907E-04 ! positive regulation of endothelial cell proliferation GO:0001938 22 11 2,000 5,923E-06 8,383E-04 ! positive regulation of phosphorylation GO:0042327 129 79 4,000 7,106E-06 9,498E-04 ! cellular response to insulin stimulus GO:0032869 82 37 3,000 7,227E-06 9,151E-04 ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 2,000 7,878E-06 9,478E-04 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 4,000 8,035E-06 9,206E-04 GO:0045937|positive regulation of phosphate metabolic process, ! cellular response to hormone stimulus GO:0032870 167 82 4,000 8,534E-06 9,334E-04 ! regulation of protein transport GO:0051223 154 87 4,000 1,141E-05 1,193E-03 GO:0070201|regulation of establishment of protein localization, ! regulation of intracellular protein transport GO:0033157 80 42 3,000 1,209E-05 1,212E-03 ! glucose transport GO:0015758 65 43 3,000 1,33E-05 1,28E-03 ! positive regulation of response to external stimulus GO:0032103 77 43 3,000 1,33E-05 1,23E-03 ! regulation of epithelial cell proliferation GO:0050678 111 43 3,000 1,33E-05 1,185E-03 ! hexose transport GO:0008645 67 44 3,000 1,459E-05 1,254E-03 GO:0015749|monosaccharide transport, ! regulation of nucleocytoplasmic transport GO:0046822 85 46 3,000 1,745E-05 1,447E-03 ! response to insulin stimulus GO:0032868 95 46 3,000 1,745E-05 1,399E-03 ! regulation of protein localization GO:0032880 176 97 4,000 1,937E-05 1,504E-03 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 2,000 1,986E-05 1,493E-03 ! positive regulation of cell cycle GO:0045787 89 48 3,000 2,07E-05 1,509E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 2,000 2,406E-05 1,702E-03 ! negative regulation of blood coagulation GO:0030195 24 17 2,000 2,406E-05 1,654E-03 ! positive regulation of growth GO:0045927 90 52 3,000 2,85E-05 1,905E-03 ! regulation of DNA replication GO:0006275 101 56 3,000 3,827E-05 2,489E-03 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 2,000 4,004E-05 2,535E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 2,000 4,004E-05 2,47E-03 ! negative regulation of coagulation GO:0050819 29 20 2,000 4,004E-05 2,408E-03 ! regulation of intracellular transport GO:0032386 101 57 3,000 4,105E-05 2,409E-03 ! positive regulation of locomotion GO:0040017 39 21 2,000 4,659E-05 2,669E-03 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! response to peptide hormone stimulus GO:0043434 122 61 3,000 5,368E-05 3,004E-03 ! regulation of chemotaxis GO:0050920 40 22 2,000 5,382E-05 2,943E-03 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 2,000 5,382E-05 2,878E-03 ! positive regulation of intracellular transport GO:0032388 37 22 2,000 5,382E-05 2,815E-03 ! positive regulation of DNA replication GO:0045740 43 23 2,000 6,174E-05 3,161E-03 ! positive regulation of fibroblast proliferation GO:0048146 43 24 2,000 7,039E-05 3,528E-03 ! regulation of behavior GO:0050795 43 24 2,000 7,039E-05 3,456E-03 ! regulation of oxidoreductase activity GO:0051341 46 24 2,000 7,039E-05 3,387E-03 ! activation of MAPK activity GO:0000187 115 67 3,000 7,764E-05 3,663E-03 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 2,000 7,98E-05 3,692E-03 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 2,000 7,98E-05 3,622E-03 ! regulation of blood coagulation GO:0030193 40 25 2,000 7,98E-05 3,555E-03 ! regulation of endothelial cell proliferation GO:0001936 57 26 2,000 8,998E-05 3,936E-03 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 2,000 8,998E-05 3,866E-03 ! regulation of fibroblast proliferation GO:0048145 52 27 2,000 1,01E-04 4,263E-03 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 2,000 1,01E-04 4,189E-03 ! carbohydrate transport GO:0008643 110 72 3,000 1,029E-04 4,196E-03 ! negative regulation of bone resorption GO:0045779 10 5 1,000 1,106E-04 4,436E-03 ! 2-oxoglutarate metabolic process GO:0006103 7 5 1,000 1,106E-04 4,363E-03 ! positive regulation of glycolysis GO:0045821 14 5 1,000 1,106E-04 4,293E-03 ! valine metabolic process GO:0006573 10 5 1,000 1,106E-04 4,225E-03 ! muscle cell migration GO:0014812 8 5 1,000 1,106E-04 4,159E-03 ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 1,000 1,106E-04 4,095E-03 ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 1,106E-04 4,033E-03 ! early endosome to late endosome transport GO:0045022 12 5 1,000 1,106E-04 3,973E-03 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 1,000 1,106E-04 3,914E-03 ! muscle cell proliferation GO:0033002 11 5 1,000 1,106E-04 3,857E-03 ! inner cell mass cell proliferation GO:0001833 5 5 1,000 1,106E-04 3,802E-03 ! peptidyl-tyrosine modification GO:0018212 50 28 2,000 1,128E-04 3,823E-03 ! regulation of coagulation GO:0050818 46 29 2,000 1,255E-04 4,195E-03 ! regulation of catabolic process GO:0009894 161 76 3,000 1,27E-04 4,186E-03 ! response to hypoxia GO:0001666 171 81 3,000 1,626E-04 5,286E-03 ! male meiosis GO:0007140 7 6 1,000 1,656E-04 5,312E-03 ! cGMP-mediated signaling GO:0019934 13 6 1,000 1,656E-04 5,242E-03 ! positive regulation of muscle hypertrophy GO:0014742 10 6 1,000 1,656E-04 5,174E-03 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! negative regulation of platelet activation GO:0010544 9 6 1,000 1,656E-04 5,107E-03 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 1,000 1,656E-04 5,043E-03 ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 1,000 1,656E-04 4,98E-03 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! response to UV-C GO:0010225 11 6 1,000 1,656E-04 4,918E-03 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 1,000 1,656E-04 4,858E-03 ! cytoplasmic microtubule organization GO:0031122 14 6 1,000 1,656E-04 4,8E-03 ! positive regulation of catabolic process GO:0009896 64 32 2,000 1,692E-04 4,846E-03 ! response to oxygen levels GO:0070482 176 83 3,000 1,787E-04 5,057E-03 ! negative regulation of protein transport GO:0051224 69 33 2,000 1,856E-04 5,194E-03 ! negative regulation of transport GO:0051051 153 84 3,000 1,871E-04 5,175E-03 ! cytokinesis during cell cycle GO:0033205 11 7 1,000 2,313E-04 6,324E-03 ! mRNA stabilization GO:0048255 18 7 1,000 2,313E-04 6,253E-03 GO:0043489|RNA stabilization, ! glucocorticoid receptor signaling pathway GO:0042921 13 7 1,000 2,313E-04 6,183E-03 GO:0031958|corticosteroid receptor signaling pathway, ! oxaloacetate metabolic process GO:0006107 10 7 1,000 2,313E-04 6,115E-03 ! regulation of granule cell precursor proliferation GO:0021936 13 7 1,000 2,313E-04 6,049E-03 GO:0021940|positive regulation of granule cell precursor proliferation, ! positive regulation of mitotic cell cycle GO:0045931 12 7 1,000 2,313E-04 5,984E-03 ! centrosome duplication GO:0051298 13 7 1,000 2,313E-04 5,92E-03 ! fibrinolysis GO:0042730 10 7 1,000 2,313E-04 5,858E-03 ! regulation of respiratory burst GO:0060263 11 7 1,000 2,313E-04 5,797E-03 ! muscle adaptation GO:0043500 14 7 1,000 2,313E-04 5,737E-03 ! negative regulation of cell activation GO:0050866 65 36 2,000 2,412E-04 5,921E-03 ! tissue remodeling GO:0048771 76 37 2,000 2,618E-04 6,363E-03 ! negative regulation of multicellular organismal process GO:0051241 166 93 3,000 2,767E-04 6,657E-03 ! positive regulation of DNA metabolic process GO:0051054 72 38 2,000 2,836E-04 6,755E-03 ! mammary gland development GO:0030879 86 39 2,000 3,064E-04 7,228E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 3,077E-04 7,188E-03 ! cardiac muscle cell differentiation GO:0055007 27 8 1,000 3,077E-04 7,119E-03 ! succinate metabolic process GO:0006105 14 8 1,000 3,077E-04 7,051E-03 ! T-helper 1 type immune response GO:0042088 12 8 1,000 3,077E-04 6,985E-03 ! ER overload response GO:0006983 12 8 1,000 3,077E-04 6,919E-03 ! regulation of muscle hypertrophy GO:0014743 12 8 1,000 3,077E-04 6,855E-03 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! regulation of vascular permeability GO:0043114 12 8 1,000 3,077E-04 6,792E-03 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 1,000 3,077E-04 6,731E-03 ! blastocyst growth GO:0001832 19 8 1,000 3,077E-04 6,67E-03 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 1,000 3,077E-04 6,611E-03 ! regulation of DNA metabolic process GO:0051052 178 97 3,000 3,25E-04 6,92E-03 ! regulation of developmental growth GO:0048638 15 9 1,000 3,948E-04 8,332E-03 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 3,948E-04 8,259E-03 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 1,000 3,948E-04 8,188E-03 GO:0010469|regulation of receptor activity, ! induction of positive chemotaxis GO:0050930 15 9 1,000 3,948E-04 8,118E-03 ! regulation of glycolysis GO:0006110 21 9 1,000 3,948E-04 8,049E-03 ! keratinocyte proliferation GO:0043616 14 9 1,000 3,948E-04 7,982E-03 ! phosphagen metabolic process GO:0006599 12 9 1,000 3,948E-04 7,915E-03 GO:0006600|creatine metabolic process, ! retinoic acid receptor signaling pathway GO:0048384 15 9 1,000 3,948E-04 7,85E-03 ! receptor clustering GO:0043113 18 9 1,000 3,948E-04 7,785E-03 ! motor axon guidance GO:0008045 16 9 1,000 3,948E-04 7,722E-03 ! induction of an organ GO:0001759 14 9 1,000 3,948E-04 7,66E-03 ! regulation of muscle adaptation GO:0043502 14 9 1,000 3,948E-04 7,599E-03 ! induction of apoptosis by intracellular signals GO:0008629 93 45 2,000 4,689E-04 8,954E-03 ! cell growth GO:0016049 84 45 2,000 4,689E-04 8,884E-03 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 1,000 4,924E-04 9,255E-03 ! regulation of smooth muscle cell migration GO:0014910 27 10 1,000 4,924E-04 9,184E-03 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 1,000 4,924E-04 9,113E-03 ! lung alveolus development GO:0048286 26 10 1,000 4,924E-04 9,043E-03 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 1,000 4,924E-04 8,975E-03 ! multicellular organism growth GO:0035264 18 10 1,000 4,924E-04 8,907E-03 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 1,000 4,924E-04 8,841E-03 ! regulation of bone resorption GO:0045124 25 10 1,000 4,924E-04 8,775E-03 ! positive regulation of leukocyte migration GO:0002687 25 10 1,000 4,924E-04 8,711E-03 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 1,000 4,924E-04 8,647E-03 GO:0043470|regulation of carbohydrate catabolic process, ! oocyte development GO:0048599 17 10 1,000 4,924E-04 8,585E-03 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 1,000 4,924E-04 8,523E-03 ! localization within membrane GO:0051668 20 10 1,000 4,924E-04 8,462E-03 ! regulation of gene-specific transcription GO:0032583 96 46 2,000 5,004E-04 8,539E-03 ! positive regulation of protein transport GO:0051222 72 46 2,000 5,004E-04 8,479E-03 ! vascular process in circulatory system GO:0003018 80 47 2,000 5,332E-04 8,972E-03 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 1,000 6,005E-04 0,01003324 ! substrate-bound cell migration GO:0006929 13 11 1,000 6,005E-04 9,964E-03 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 1,000 6,005E-04 9,896E-03 ! regulation of leukocyte migration GO:0002685 26 11 1,000 6,005E-04 9,828E-03 ! nitric oxide mediated signal transduction GO:0007263 23 11 1,000 6,005E-04 9,762E-03 ! oocyte differentiation GO:0009994 18 11 1,000 6,005E-04 9,697E-03 ! cardiac cell differentiation GO:0035051 31 11 1,000 6,005E-04 9,632E-03 ! developmental induction GO:0031128 19 11 1,000 6,005E-04 9,568E-03 GO:0045168|cell-cell signaling involved in cell fate specification, ! regulation of embryonic development GO:0045995 27 11 1,000 6,005E-04 9,505E-03 ! regulation of gene expression, epigenetic GO:0040029 105 50 2,000 6,399E-04 0,01006244 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 2,000 6,782E-04 0,01059616 ! positive regulation of cellular catabolic process GO:0031331 31 12 1,000 7,19E-04 0,01116099 ! virus-host interaction GO:0019048 29 12 1,000 7,19E-04 0,01108944 ! regulation of positive chemotaxis GO:0050926 19 12 1,000 7,19E-04 0,01101881 GO:0050927|positive regulation of positive chemotaxis, ! dopamine receptor signaling pathway GO:0007212 28 12 1,000 7,19E-04 0,01094907 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 1,000 7,19E-04 0,01088021 ! positive regulation of cell growth GO:0030307 22 12 1,000 7,19E-04 0,0108122 ! histone acetylation GO:0016573 26 12 1,000 7,19E-04 0,01074505 ! negative regulation of mast cell proliferation GO:0070667 23 12 1,000 7,19E-04 0,01067872 GO:0042130|negative regulation of T cell proliferation, ! response to UV GO:0009411 104 53 2,000 7,592E-04 0,01120692 ! activation of phospholipase C activity GO:0007202 103 54 2,000 8,02E-04 0,01176522 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of phospholipase activity GO:0010518 104 55 2,000 8,462E-04 0,01233859 ! regulation of protein catabolic process GO:0042176 116 55 2,000 8,462E-04 0,01226426 ! heart morphogenesis GO:0003007 97 55 2,000 8,462E-04 0,01219082 ! double-strand break repair via homologous recombination GO:0000724 19 13 1,000 8,479E-04 0,01214298 GO:0000725|recombinational repair, ! negative regulation of lipid metabolic process GO:0045833 19 13 1,000 8,479E-04 0,01207112 ! response to X-ray GO:0010165 25 13 1,000 8,479E-04 0,01200012 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 1,000 8,479E-04 0,01192994 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of monooxygenase activity GO:0032768 33 13 1,000 8,479E-04 0,01186058 ! chromatin silencing GO:0006342 26 13 1,000 8,479E-04 0,01179202 ! regulation of mRNA stability GO:0043488 31 13 1,000 8,479E-04 0,01172425 ! cytoplasmic sequestering of protein GO:0051220 24 13 1,000 8,479E-04 0,01165726 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 2,000 9,392E-04 0,01283875 ! regulation of phospholipase activity GO:0010517 106 57 2,000 9,392E-04 0,01276622 ! regulation of S phase GO:0033261 23 14 1,000 9,87E-04 0,0133417 ! regulation of mRNA processing GO:0050684 24 14 1,000 9,87E-04 0,01326716 ! actin cytoskeleton reorganization GO:0031532 33 14 1,000 9,87E-04 0,01319345 ! negative regulation of caspase activity GO:0043154 22 14 1,000 9,87E-04 0,01312056 ! response to gamma radiation GO:0010332 28 14 1,000 9,87E-04 0,01304847 ! regulation of RNA stability GO:0043487 32 14 1,000 9,87E-04 0,01297717 ! release of cytochrome c from mitochondria GO:0001836 30 14 1,000 9,87E-04 0,01290664 ! positive regulation of lipase activity GO:0060193 108 58 2,000 9,88E-04 0,01284919 ! integrin-mediated signaling pathway GO:0007229 135 59 2,000 1,038E-03 0,01343215 ! DNA damage response, signal transduction GO:0042770 128 60 2,000 1,09E-03 0,01402944 ! positive regulation of cell size GO:0045793 27 15 1,000 1,136E-03 0,01454357 ! negative regulation of bone remodeling GO:0046851 33 15 1,000 1,136E-03 0,01446662 ! intermediate filament cytoskeleton organization GO:0045104 31 15 1,000 1,136E-03 0,01439048 ! positive regulation of oxidoreductase activity GO:0051353 22 15 1,000 1,136E-03 0,01431514 ! regulation of homeostatic process GO:0032844 134 62 2,000 1,199E-03 0,01502853 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 1,296E-03 0,01615526 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 1,000 1,296E-03 0,01607198 ! activation of MAPKK activity GO:0000186 35 16 1,000 1,296E-03 0,01598956 ! intermediate filament-based process GO:0045103 32 16 1,000 1,296E-03 0,01590798 ! axon cargo transport GO:0008088 43 16 1,000 1,296E-03 0,01582723 ! positive regulation of protein import into nucleus GO:0042307 30 16 1,000 1,296E-03 0,0157473 ! negative regulation of tissue remodeling GO:0034104 36 16 1,000 1,296E-03 0,01566816 ! negative regulation of leukocyte proliferation GO:0070664 31 16 1,000 1,296E-03 0,01558982 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! signal complex assembly GO:0007172 41 17 1,000 1,465E-03 0,01754217 ! negative regulation of peptidase activity GO:0010466 27 17 1,000 1,465E-03 0,01745533 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 1,000 1,465E-03 0,01736934 ! negative regulation of protein catabolic process GO:0042177 40 17 1,000 1,465E-03 0,01728419 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 1,000 1,465E-03 0,01719988 ! branched chain family amino acid metabolic process GO:0009081 33 17 1,000 1,465E-03 0,01711639 ! negative regulation of homeostatic process GO:0032845 33 17 1,000 1,465E-03 0,0170337 ! lung development GO:0030324 144 67 2,000 1,501E-03 0,01736012 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 2,000 1,566E-03 0,01803074 ! regulation of lipase activity GO:0060191 130 68 2,000 1,566E-03 0,01794488 ! regulation of lipid biosynthetic process GO:0046890 25 18 1,000 1,645E-03 0,01875859 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 1,645E-03 0,0186701 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 1,000 1,645E-03 0,01858245 GO:0050886|endocrine process, ! centrosome cycle GO:0007098 25 18 1,000 1,645E-03 0,01849562 ! response to retinoic acid GO:0032526 26 18 1,000 1,645E-03 0,01840959 ! peptidyl-serine phosphorylation GO:0018105 38 18 1,000 1,645E-03 0,01832436 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 1,000 1,645E-03 0,01823992 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 1,000 1,645E-03 0,01815625 ! respiratory tube development GO:0030323 150 70 2,000 1,703E-03 0,01870428 ! skin development GO:0043588 36 19 1,000 1,835E-03 0,02006391 ! lipid phosphorylation GO:0046834 35 19 1,000 1,835E-03 0,01997312 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 1,000 1,835E-03 0,01988315 ! response to vitamin A GO:0033189 27 19 1,000 1,835E-03 0,01979399 ! neuromuscular junction development GO:0007528 34 19 1,000 1,835E-03 0,01970563 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 1,000 1,835E-03 0,01961805 ! estrogen receptor signaling pathway GO:0030520 38 19 1,000 1,835E-03 0,01953124 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 2,000 1,846E-03 0,01956544 ! respiratory system development GO:0060541 153 72 2,000 1,846E-03 0,01947963 ! regulation of transcription factor activity GO:0051090 126 74 2,000 1,997E-03 0,02097859 GO:0090046|regulation of transcription regulator activity, ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 1,000 2,034E-03 0,02127743 ! protein amino acid acetylation GO:0006473 39 20 1,000 2,034E-03 0,02118532 ! response to vitamin GO:0033273 31 20 1,000 2,034E-03 0,021094 ! regulation of carbohydrate metabolic process GO:0006109 38 20 1,000 2,034E-03 0,02100347 GO:0010675|regulation of cellular carbohydrate metabolic process, ! apoptotic mitochondrial changes GO:0008637 41 20 1,000 2,034E-03 0,02091371 ! peptidyl-serine modification GO:0018209 43 20 1,000 2,034E-03 0,02082472 ! negative regulation of T cell activation GO:0050868 40 20 1,000 2,034E-03 0,02073648 ! phosphoinositide-mediated signaling GO:0048015 131 75 2,000 2,075E-03 0,02106404 ! cell aging GO:0007569 44 21 1,000 2,243E-03 0,02267708 ! regulation of vasoconstriction GO:0019229 39 21 1,000 2,243E-03 0,0225822 ! oogenesis GO:0048477 36 21 1,000 2,243E-03 0,02248811 ! negative regulation of intracellular transport GO:0032387 41 21 1,000 2,243E-03 0,02239479 ! positive regulation of inflammatory response GO:0050729 35 21 1,000 2,243E-03 0,02230225 ! blood coagulation GO:0007596 146 78 2,000 2,321E-03 0,02297818 GO:0050817|coagulation, ! protein oligomerization GO:0051259 139 78 2,000 2,321E-03 0,022884 ! activation of protein kinase activity GO:0032147 147 79 2,000 2,407E-03 0,02363302 ! positive regulation of protein catabolic process GO:0045732 38 22 1,000 2,462E-03 0,02408094 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 1,000 2,462E-03 0,02398344 ! microtubule-based transport GO:0010970 54 22 1,000 2,462E-03 0,02388674 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 1,000 2,462E-03 0,02379081 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 1,000 2,462E-03 0,02369564 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 1,000 2,462E-03 0,02360124 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 1,000 2,462E-03 0,02350758 ! protein stabilization GO:0050821 39 22 1,000 2,462E-03 0,02341467 ! response to nutrient GO:0007584 125 82 2,000 2,676E-03 0,0253442 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 1,000 2,691E-03 0,02538802 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 2,691E-03 0,02528885 ! sex determination GO:0007530 47 23 1,000 2,691E-03 0,02519045 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 1,000 2,691E-03 0,02509281 ! platelet activation GO:0030168 37 23 1,000 2,691E-03 0,02499593 ! negative regulation of catabolic process GO:0009895 50 23 1,000 2,691E-03 0,02489979 ! hemostasis GO:0007599 158 84 2,000 2,865E-03 0,02640921 ! regulation of cellular catabolic process GO:0031329 52 24 1,000 2,929E-03 0,02689729 ! protein tetramerization GO:0051262 52 24 1,000 2,929E-03 0,02679502 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 1,000 3,177E-03 0,02895146 ! myelination GO:0042552 45 25 1,000 3,177E-03 0,02884221 ! dicarboxylic acid metabolic process GO:0043648 42 25 1,000 3,177E-03 0,02873378 ! protein amino acid alkylation GO:0008213 53 25 1,000 3,177E-03 0,02862616 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 1,000 3,177E-03 0,02851935 ! negative regulation of DNA replication GO:0008156 42 25 1,000 3,177E-03 0,02841333 ! receptor metabolic process GO:0043112 46 25 1,000 3,177E-03 0,02830809 ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 3,177E-03 0,02820363 ! interaction with host GO:0051701 62 25 1,000 3,177E-03 0,02809994 ! positive regulation of protein modification process GO:0031401 136 88 2,000 3,268E-03 0,02879829 ! regulation of DNA binding GO:0051101 155 88 2,000 3,268E-03 0,02869319 ! gland development GO:0048732 206 88 2,000 3,268E-03 0,02858885 ! regulation of transcription factor import into nucleus GO:0042990 54 26 1,000 3,434E-03 0,02993505 ! microtubule organizing center organization GO:0031023 39 26 1,000 3,434E-03 0,02982699 GO:0051297|centrosome organization, ! positive regulation of nuclear division GO:0051785 40 26 1,000 3,434E-03 0,02971969 GO:0045840|positive regulation of mitosis, ! blastocyst development GO:0001824 49 26 1,000 3,434E-03 0,02961317 ! regulation of cell cycle process GO:0010564 149 90 2,000 3,481E-03 0,02991502 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 1,000 3,701E-03 0,03168542 ! protein amino acid acylation GO:0043543 55 27 1,000 3,701E-03 0,03157306 ! negative regulation of lymphocyte activation GO:0051250 53 27 1,000 3,701E-03 0,0314615 ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 3,977E-03 0,03368878 ! regulation of systemic arterial blood pressure GO:0003073 54 28 1,000 3,977E-03 0,03357057 ! response to organic cyclic substance GO:0014070 55 29 1,000 4,262E-03 0,03585298 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 1,000 4,262E-03 0,03572805 ! tissue homeostasis GO:0001894 48 29 1,000 4,262E-03 0,035604 GO:0048871|multicellular organismal homeostasis, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 2,000 4,548E-03 0,03786507 ! positive regulation of multicellular organism growth GO:0040018 51 30 1,000 4,556E-03 0,0378016 ! ensheathment of neurons GO:0007272 57 30 1,000 4,556E-03 0,03767169 GO:0008366|axon ensheathment, ! negative regulation of leukocyte activation GO:0002695 56 30 1,000 4,556E-03 0,03754268 ! cell cycle arrest GO:0007050 213 100 2,000 4,678E-03 0,03841054 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 1,000 4,86E-03 0,03977209 ! negative regulation of transcription regulator activity GO:0090048 58 31 1,000 4,86E-03 0,03963727 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 1,000 5,173E-03 0,04204524 ! response to ionizing radiation GO:0010212 65 32 1,000 5,173E-03 0,04190367 ! regulation of protein import into nucleus GO:0042306 63 32 1,000 5,173E-03 0,04176306 ! peripheral nervous system development GO:0007422 64 32 1,000 5,173E-03 0,04162338 ! gene silencing GO:0016458 65 32 1,000 5,173E-03 0,04148464 ! cell fate specification GO:0001708 52 33 1,000 5,494E-03 0,04391862 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 1,000 5,825E-03 0,04640788 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 1,000 5,825E-03 0,04625472 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 1,000 6,165E-03 0,04879037 ! negative regulation of secretion GO:0051048 63 35 1,000 6,165E-03 0,0486304 ! negative regulation of DNA metabolic process GO:0051053 61 35 1,000 6,165E-03 0,04847147 ! female gonad development GO:0008585 58 35 1,000 6,165E-03 0,04831359 ! negative regulation of hydrolase activity GO:0051346 62 35 1,000 6,165E-03 0,04815672 ! calcium-mediated signaling GO:0019722 62 35 1,000 6,165E-03 0,04800088 ! regulation of microtubule-based process GO:0032886 78 35 1,000 6,165E-03 0,04784604 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 1,000 6,513E-03 0,05038786 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 1,000 6,513E-03 0,05022636 ! maintenance of protein location in cell GO:0032507 86 36 1,000 6,513E-03 0,0500659 ! negative regulation of DNA binding GO:0043392 68 37 1,000 6,87E-03 0,05264361 ! regulation of protein stability GO:0031647 73 37 1,000 6,87E-03 0,05247649 ! glycogen metabolic process GO:0005977 61 37 1,000 6,87E-03 0,05231043 ! carbohydrate homeostasis GO:0033500 53 38 1,000 7,236E-03 0,05492281 GO:0042593|glucose homeostasis, ! development of primary female sexual characteristics GO:0046545 67 38 1,000 7,236E-03 0,0547501 GO:0046660|female sex differentiation, ! glucan metabolic process GO:0044042 62 38 1,000 7,236E-03 0,05457847 GO:0006073|cellular glucan metabolic process, ! regulation of action potential in neuron GO:0019228 73 39 1,000 7,611E-03 0,05722433 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 1,000 7,994E-03 0,05991812 ! negative regulation of binding GO:0051100 72 40 1,000 7,994E-03 0,05973203 ! multicellular organismal metabolic process GO:0044236 57 40 1,000 7,994E-03 0,05954711 ! maintenance of protein location GO:0045185 91 40 1,000 7,994E-03 0,05936332 ! cytokinesis GO:0000910 72 40 1,000 7,994E-03 0,05918066 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 1,000 8,386E-03 0,06189009 ! cellular amide metabolic process GO:0043603 67 41 1,000 8,386E-03 0,06170083 ! regulation of T cell proliferation GO:0042129 71 41 1,000 8,386E-03 0,06151271 ! keratinocyte differentiation GO:0030216 62 41 1,000 8,386E-03 0,06132575 ! regulation of T cell differentiation GO:0045580 70 41 1,000 8,386E-03 0,06113991 ! female gamete generation GO:0007292 61 41 1,000 8,386E-03 0,0609552 ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 8,786E-03 0,06367171 GO:0090047|positive regulation of transcription regulator activity, ! regulation of tube size GO:0035150 71 42 1,000 8,786E-03 0,0634805 GO:0050880|regulation of blood vessel size, ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 1,000 8,786E-03 0,06329044 ! regulation of protein secretion GO:0050708 71 42 1,000 8,786E-03 0,06310151 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 1,000 9,195E-03 0,06583953 ! receptor-mediated endocytosis GO:0006898 88 43 1,000 9,195E-03 0,06564416 ! energy reserve metabolic process GO:0006112 74 43 1,000 9,195E-03 0,06544994 ! striated muscle cell differentiation GO:0051146 82 43 1,000 9,195E-03 0,06525688 ! double-strand break repair GO:0006302 81 44 1,000 9,611E-03 0,06801544 ! biopolymer methylation GO:0043414 84 44 1,000 9,611E-03 0,06781598 ! JAK-STAT cascade GO:0007259 71 44 1,000 9,611E-03 0,06761769 ! developmental growth GO:0048589 82 44 1,000 9,611E-03 0,06742055 ! maintenance of location in cell GO:0051651 97 44 1,000 9,611E-03 0,06722456 ! regulation of JAK-STAT cascade GO:0046425 70 45 1,000 0,01003673 0,06999526 ! branching morphogenesis of a tube GO:0048754 97 45 1,000 0,01003673 0,06979296 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 1,000 0,0104702 0,07259738 ! negative regulation of cell migration GO:0030336 115 46 1,000 0,0104702 0,07238877 ! epidermal cell differentiation GO:0009913 68 46 1,000 0,0104702 0,07218135 ! positive regulation of defense response GO:0031349 76 47 1,000 0,01091184 0,07501109 ! endosome transport GO:0016197 108 47 1,000 0,01091184 0,07479739 ! positive regulation of DNA binding GO:0043388 73 47 1,000 0,01091184 0,07458489 ! regulation of JNK cascade GO:0046328 94 47 1,000 0,01091184 0,07437361 ! methylation GO:0032259 90 47 1,000 0,01091184 0,07416351 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 1,000 0,0113616 0,07700282 ! regulation of inflammatory response GO:0050727 75 48 1,000 0,0113616 0,07678652 ! regulation of lymphocyte differentiation GO:0045619 81 48 1,000 0,0113616 0,07657143 ! regulation of mast cell proliferation GO:0070666 81 48 1,000 0,0113616 0,07635754 ! regulation of action potential GO:0001508 95 49 1,000 0,01181941 0,0792131 ! DNA-dependent DNA replication GO:0006261 74 49 1,000 0,01181941 0,07899306 ! histone modification GO:0016570 91 50 1,000 0,01228522 0,08187881 ! negative regulation of immune system process GO:0002683 95 50 1,000 0,01228522 0,08165262 ! positive regulation of cytokine production GO:0001819 86 50 1,000 0,01228522 0,08142769 ! positive regulation of binding GO:0051099 78 51 1,000 0,01275898 0,08433545 ! response to estrogen stimulus GO:0043627 93 51 1,000 0,01275898 0,0841044 ! regulation of leukocyte proliferation GO:0070663 88 51 1,000 0,01275898 0,0838746 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of cell shape GO:0008360 125 51 1,000 0,01275898 0,08364606 ! regulation of angiogenesis GO:0045765 114 52 1,000 0,01324062 0,08656774 ! covalent chromatin modification GO:0016569 101 52 1,000 0,01324062 0,08633314 ! morphogenesis of a branching structure GO:0001763 111 52 1,000 0,01324062 0,08609981 ! synapse organization GO:0050808 85 52 1,000 0,01324062 0,08586773 ! cell maturation GO:0048469 100 53 1,000 0,01373008 0,08880264 ! cellular polysaccharide metabolic process GO:0044264 86 55 1,000 0,01473227 0,09502906 ! aging GO:0007568 103 55 1,000 0,01473227 0,09477498 ! regulation of multicellular organism growth GO:0040014 85 55 1,000 0,01473227 0,09452224 ! negative regulation of cell motion GO:0051271 134 55 1,000 0,01473227 0,09427085 ! skeletal muscle fiber development GO:0048741 111 56 1,000 0,01524488 0,09729223 ! nucleotide-excision repair GO:0006289 83 56 1,000 0,01524488 0,09703485 ! positive regulation of organelle organization GO:0010638 100 56 1,000 0,01524488 0,09677882 ! regulation of bone remodeling GO:0046850 137 57 1,000 0,01576508 0,09981787 ! muscle fiber development GO:0048747 112 57 1,000 0,01576508 0,09955589 ! lipid modification GO:0030258 97 57 1,000 0,01576508 0,09929527 ! maintenance of location GO:0051235 118 57 1,000 0,01576508 0,09903601 ! regulation of tissue remodeling GO:0034103 140 58 1,000 0,01629284 0,10208481 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,01665695 0,10409511 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,01665695 0,10382543 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,01665695 0,10355715 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,01665695 0,10329025 ! neuron fate determination GO:0048664 7 5 0,000 0,01665695 0,10302472 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01665695 0,10276056 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,01665695 0,10249774 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,01665695 0,10223627 ! polyol transport GO:0015791 12 5 0,000 0,01665695 0,10197613 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,01665695 0,1017173 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,01665695 0,10145979 ! response to superoxide GO:0000303 10 5 0,000 0,01665695 0,10120358 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,01665695 0,10094866 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,01665695 0,10069502 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,01665695 0,10044265 ! female meiosis GO:0007143 7 5 0,000 0,01665695 0,10019154 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,01665695 0,09994169 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,01665695 0,09969308 ! cobalt ion transport GO:0006824 11 5 0,000 0,01665695 0,0994457 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,01665695 0,09919955 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,01665695 0,09895461 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,01665695 0,09871088 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,01665695 0,09846835 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,01665695 0,098227 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,01665695 0,09798684 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,01665695 0,09774785 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,01665695 0,09751002 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,01665695 0,09727334 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,01665695 0,09703781 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01665695 0,09680342 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,01665695 0,09657016 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 0,01665695 0,09633802 ! negative chemotaxis GO:0050919 14 5 0,000 0,01665695 0,096107 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,01665695 0,09587707 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,01665695 0,09564825 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,01665695 0,09542052 ! behavioral response to pain GO:0048266 9 5 0,000 0,01665695 0,09519387 ! clathrin coat assembly GO:0048268 14 5 0,000 0,01665695 0,09496829 ! Notch receptor processing GO:0007220 8 5 0,000 0,01665695 0,09474378 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01665695 0,09452032 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,01665695 0,09429792 ! micturition GO:0060073 9 5 0,000 0,01665695 0,09407657 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,01665695 0,09385625 ! copulation GO:0007620 9 5 0,000 0,01665695 0,09363696 ! glial cell fate commitment GO:0021781 13 5 0,000 0,01665695 0,09341869 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,01665695 0,09320144 ! spermidine metabolic process GO:0008216 7 5 0,000 0,01665695 0,09298519 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,01665695 0,09276995 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,01665695 0,0925557 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,01665695 0,09234244 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,01665695 0,09213015 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,01665695 0,09191885 ! grooming behavior GO:0007625 6 5 0,000 0,01665695 0,09170851 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,01665695 0,09149913 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,01665695 0,0912907 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01665695 0,09108322 ! response to protozoan GO:0001562 10 5 0,000 0,01665695 0,09087668 ! lymph vessel development GO:0001945 10 5 0,000 0,01665695 0,09067108 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,01665695 0,0904664 ! endochondral ossification GO:0001958 16 5 0,000 0,01665695 0,09026265 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,01665695 0,09005981 ! parathyroid gland development GO:0060017 13 5 0,000 0,01665695 0,08985789 ! anagen GO:0042640 6 5 0,000 0,01665695 0,08965686 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,01665695 0,08945674 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,01665695 0,0892575 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,01665695 0,08905915 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,01665695 0,08886168 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,01665695 0,08866508 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,01665695 0,08846935 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,01665695 0,08827449 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,01665695 0,08808048 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,01665695 0,08788732 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,01665695 0,08769501 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,01665695 0,08750353 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,01665695 0,08731289 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,01665695 0,08712308 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,01665695 0,08693409 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,01665695 0,08674592 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,01665695 0,08655857 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 0,01665695 0,08637202 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,01665695 0,08618627 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,01665695 0,08600132 ! histidine catabolic process GO:0006548 6 5 0,000 0,01665695 0,08581717 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,01665695 0,0856338 ! microvillus organization GO:0032528 7 5 0,000 0,01665695 0,08545121 GO:0030033|microvillus assembly, ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,01665695 0,0852694 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,01665695 0,08508836 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,01665695 0,08490809 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,01665695 0,08472858 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,01665695 0,08454983 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,01665695 0,08437183 ! polyol catabolic process GO:0046174 7 5 0,000 0,01665695 0,08419457 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,01665695 0,08401807 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,01665695 0,0838423 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,01665695 0,08366726 ! mitochondrial fission GO:0000266 8 5 0,000 0,01665695 0,08349295 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,01665695 0,08331937 ! mRNA transcription GO:0009299 9 5 0,000 0,01665695 0,08314651 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,01665695 0,08297436 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,01665695 0,08280293 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,01665695 0,0826322 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,01665695 0,08246218 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,01665695 0,08229285 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,01665695 0,08212422 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,01665695 0,08195627 ! response to food GO:0032094 6 5 0,000 0,01665695 0,08178901 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,01665695 0,08162244 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,01665695 0,08145654 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,01665695 0,08129131 GO:0032881|regulation of polysaccharide metabolic process, ! paraxial mesoderm development GO:0048339 14 5 0,000 0,01665695 0,08112676 ! forebrain neuron development GO:0021884 13 5 0,000 0,01665695 0,08096286 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,01665695 0,08079963 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,01665695 0,08063706 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,01665695 0,08047514 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01665695 0,08031386 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,01665695 0,08015323 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,01665695 0,07999325 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01665695 0,0798339 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,01665695 0,07967518 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,01665695 0,0795171 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,01665695 0,07935964 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,01665695 0,0792028 ! basic amino acid transport GO:0015802 11 5 0,000 0,01665695 0,07904658 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,01665695 0,07889098 ! depyrimidination GO:0045008 10 5 0,000 0,01665695 0,07873599 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,01665695 0,0785816 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01665695 0,07842782 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,01665695 0,07827464 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,01665695 0,07812206 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 0,01665695 0,07797007 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,01665695 0,07781867 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01665695 0,07766786 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,01665695 0,07751763 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,01665695 0,07736799 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,01665695 0,07721892 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,01665695 0,07707042 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,01665695 0,07692249 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01665695 0,07677513 ! response to arsenic GO:0046685 10 5 0,000 0,01665695 0,07662833 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,01665695 0,07648209 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,01665695 0,07633641 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,01665695 0,07619129 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,01665695 0,07604671 ! response to cadmium ion GO:0046686 7 5 0,000 0,01665695 0,07590268 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,01665695 0,0757592 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,01665695 0,07561626 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,01665695 0,07547386 ! decidualization GO:0046697 11 5 0,000 0,01665695 0,07533199 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,01665695 0,07519065 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,01665695 0,07504985 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,01665695 0,07490957 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,01665695 0,07476981 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,01665695 0,07463057 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,01665695 0,07449185 ! neural tube patterning GO:0021532 7 5 0,000 0,01665695 0,07435365 ! embryonic cleavage GO:0040016 6 5 0,000 0,01665695 0,07421596 ! peroxisome fission GO:0016559 5 5 0,000 0,01665695 0,07407878 ! histone demethylation GO:0016577 10 5 0,000 0,01665695 0,0739421 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,01665695 0,07380593 ! mitotic recombination GO:0006312 9 5 0,000 0,01665695 0,07367025 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,01665695 0,07353508 ! metaphase plate congression GO:0051310 7 5 0,000 0,01665695 0,0734004 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01665695 0,07326621 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,01665695 0,07313251 ! enteric nervous system development GO:0048484 8 5 0,000 0,01665695 0,0729993 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,01665695 0,07286658 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,01665695 0,07273433 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,01665695 0,07260257 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,01665695 0,07247128 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,01665695 0,07234046 ! plasminogen activation GO:0031639 5 5 0,000 0,01665695 0,07221012 ! B cell homeostasis GO:0001782 13 5 0,000 0,01665695 0,07208025 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,01665695 0,07195084 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,01665695 0,07182189 ! metaphase GO:0051323 8 5 0,000 0,01665695 0,07169341 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,01665695 0,07156539 ! cellular response to nutrient GO:0031670 8 5 0,000 0,01665695 0,07143782 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,01665695 0,07131071 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,01665695 0,07118404 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,01665695 0,07105783 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,01665695 0,07093207 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,01665695 0,07080674 ! response to redox state GO:0051775 5 5 0,000 0,01665695 0,07068186 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,01665695 0,07055742 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,01665695 0,07043342 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,01665695 0,07030985 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,01665695 0,07018672 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01665695 0,07006402 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,01665695 0,06994174 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01665695 0,06981989 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,01665695 0,06969846 ! striatum development GO:0021756 9 5 0,000 0,01665695 0,06957746 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,01665695 0,06945688 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,01665695 0,06933671 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,01665695 0,06921696 ! glial cell migration GO:0008347 11 5 0,000 0,01665695 0,06909762 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,01665695 0,06897869 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,01665695 0,06886017 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,01665695 0,06874205 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,01665695 0,06862434 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,01665695 0,06850704 ! neuroprotection GO:0043526 6 5 0,000 0,01665695 0,06839013 ! neural plate development GO:0001840 8 5 0,000 0,01665695 0,06827362 ! regulation of sensory perception GO:0051931 7 5 0,000 0,01665695 0,06815751 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,01665695 0,0680418 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,01665695 0,06792647 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,01665695 0,06781154 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,01665695 0,06769699 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,01665695 0,06758283 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,01665695 0,06746905 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,01665695 0,06735566 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,01665695 0,06724265 ! spindle assembly GO:0051225 6 5 0,000 0,01665695 0,06713001 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,01665695 0,06701775 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,01665695 0,06690587 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,01665695 0,06679436 ! drug metabolic process GO:0017144 6 5 0,000 0,01665695 0,06668322 ! stem cell division GO:0017145 11 5 0,000 0,01665695 0,06657245 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,01665695 0,06646205 ! organ regeneration GO:0031100 7 5 0,000 0,01665695 0,06635202 ! carnitine metabolic process GO:0009437 7 5 0,000 0,01665695 0,06624234 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,01665695 0,06613303 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,01665695 0,06602408 ! kidney development GO:0001822 122 60 1,000 0,01737076 0,06874021 ! viral reproductive process GO:0022415 126 62 1,000 0,0184782 0,07300256 ! gonad development GO:0008406 98 62 1,000 0,0184782 0,07288288 ! regulation of mitosis GO:0007088 105 63 1,000 0,01904286 0,0749871 GO:0051783|regulation of nuclear division, ! regulation of lipid metabolic process GO:0019216 115 63 1,000 0,01904286 0,07486457 ! steroid hormone receptor signaling pathway GO:0030518 129 63 1,000 0,01904286 0,07474244 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 1,000 0,01961473 0,07686164 ! cell redox homeostasis GO:0045454 102 64 1,000 0,01961473 0,07673666 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,01995522 0,07794199 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,01995522 0,07781567 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,01995522 0,07768975 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,01995522 0,07756424 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,01995522 0,07743914 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,01995522 0,07731444 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,01995522 0,07719014 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,01995522 0,07706624 ! sleep GO:0030431 13 6 0,000 0,01995522 0,07694273 ! response to oxygen radical GO:0000305 11 6 0,000 0,01995522 0,07681963 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,01995522 0,07669691 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,01995522 0,07657459 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,01995522 0,07645265 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,01995522 0,07633111 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,01995522 0,07620995 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,01995522 0,07608917 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,01995522 0,07596878 ! forebrain regionalization GO:0021871 8 6 0,000 0,01995522 0,07584876 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,01995522 0,07572913 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,01995522 0,07560987 ! response to zinc ion GO:0010043 9 6 0,000 0,01995522 0,07549098 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,01995522 0,07537247 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,01995522 0,07525434 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,01995522 0,07513657 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,01995522 0,07501917 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,01995522 0,07490213 ! malate metabolic process GO:0006108 11 6 0,000 0,01995522 0,07478546 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,01995522 0,07466915 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,01995522 0,07455321 ! protein refolding GO:0042026 15 6 0,000 0,01995522 0,07443762 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,01995522 0,07432239 ! opsonization GO:0008228 8 6 0,000 0,01995522 0,07420752 ! mating behavior GO:0007617 7 6 0,000 0,01995522 0,074093 ! neuron remodeling GO:0016322 15 6 0,000 0,01995522 0,07397884 ! erythrocyte maturation GO:0043249 7 6 0,000 0,01995522 0,07386503 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,01995522 0,07375156 ! equilibrioception GO:0050957 14 6 0,000 0,01995522 0,07363845 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,01995522 0,07352568 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,01995522 0,07341325 ! photoreceptor cell development GO:0042461 10 6 0,000 0,01995522 0,07330117 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,01995522 0,07318943 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,01995522 0,07307803 ! response to interferon-gamma GO:0034341 15 6 0,000 0,01995522 0,07296697 ! toxin metabolic process GO:0009404 11 6 0,000 0,01995522 0,07285625 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,01995522 0,07274586 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,01995522 0,0726358 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,01995522 0,07252608 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,01995522 0,07241669 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,01995522 0,07230763 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,01995522 0,0721989 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,01995522 0,07209049 ! thymic T cell selection GO:0045061 12 6 0,000 0,01995522 0,07198241 ! protein lipoylation GO:0009249 10 6 0,000 0,01995522 0,07187465 ! cysteine metabolic process GO:0006534 10 6 0,000 0,01995522 0,07176721 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,01995522 0,0716601 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,01995522 0,0715533 ! glutamate catabolic process GO:0006538 10 6 0,000 0,01995522 0,07144682 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,01995522 0,07134066 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,01995522 0,07123482 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,01995522 0,07112928 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,01995522 0,07102406 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,01995522 0,07091915 ! hyperosmotic response GO:0006972 9 6 0,000 0,01995522 0,07081455 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,01995522 0,07071026 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,01995522 0,07060627 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,01995522 0,07050259 ! urea metabolic process GO:0019627 7 6 0,000 0,01995522 0,07039922 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,01995522 0,07029614 ! neutrophil activation GO:0042119 8 6 0,000 0,01995522 0,07019337 ! regulation of appetite GO:0032098 9 6 0,000 0,01995522 0,0700909 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,01995522 0,06998873 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,01995522 0,06988685 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,01995522 0,06978527 ! neuron apoptosis GO:0051402 9 6 0,000 0,01995522 0,06968399 ! nucleoside salvage GO:0043174 9 6 0,000 0,01995522 0,06958299 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,01995522 0,0694823 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,01995522 0,06938189 ! T cell mediated immunity GO:0002456 16 6 0,000 0,01995522 0,06928177 ! carnitine transport GO:0015879 10 6 0,000 0,01995522 0,06918194 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,01995522 0,0690824 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01995522 0,06898314 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,01995522 0,06888417 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,01995522 0,06878548 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,01995522 0,06868708 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,01995522 0,06858895 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,01995522 0,06849111 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,01995522 0,06839354 ! establishment of spindle localization GO:0051293 12 6 0,000 0,01995522 0,06829625 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,01995522 0,06819924 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,01995522 0,06810251 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,01995522 0,06800604 ! neural nucleus development GO:0048857 14 6 0,000 0,01995522 0,06790985 ! astrocyte development GO:0014002 15 6 0,000 0,01995522 0,06781394 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,01995522 0,06771829 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,01995522 0,06762291 ! interaction with symbiont GO:0051702 13 6 0,000 0,01995522 0,0675278 ! regulation of dendrite development GO:0050773 16 6 0,000 0,01995522 0,06743296 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,01995522 0,06733838 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,01995522 0,06724407 ! response to copper ion GO:0046688 10 6 0,000 0,01995522 0,06715002 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,01995522 0,06705624 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,01995522 0,06696271 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,01995522 0,06686945 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,01995522 0,06677645 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,01995522 0,0666837 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,01995522 0,06659122 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,01995522 0,06649898 ! hair follicle maturation GO:0048820 7 6 0,000 0,01995522 0,06640701 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,01995522 0,06631528 ! Schwann cell development GO:0014044 15 6 0,000 0,01995522 0,06622382 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,01995522 0,0661326 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,01995522 0,06604163 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,01995522 0,06595092 ! subpallium development GO:0021544 10 6 0,000 0,01995522 0,06586045 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,01995522 0,06577023 ! histone ubiquitination GO:0016574 8 6 0,000 0,01995522 0,06568025 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,01995522 0,06559053 ! maintenance of organ identity GO:0048496 9 6 0,000 0,01995522 0,06550105 ! G2 phase GO:0051319 16 6 0,000 0,01995522 0,06541181 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,01995522 0,06532281 ! establishment of planar polarity GO:0001736 7 6 0,000 0,01995522 0,06523406 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,01995522 0,06514554 ! membrane to membrane docking GO:0022614 14 6 0,000 0,01995522 0,06505727 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,01995522 0,06496924 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,01995522 0,06488144 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,01995522 0,06479388 ! receptor internalization GO:0031623 10 6 0,000 0,01995522 0,06470656 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,01995522 0,06461947 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,01995522 0,06453262 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01995522 0,06444599 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,01995522 0,06435961 ! protein deubiquitination GO:0016579 14 6 0,000 0,01995522 0,06427345 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 0,01995522 0,06418752 ! protein destabilization GO:0031648 9 6 0,000 0,01995522 0,06410182 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,01995522 0,06401636 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,01995522 0,06393111 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,01995522 0,0638461 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,01995522 0,06376131 ! progesterone metabolic process GO:0042448 10 6 0,000 0,01995522 0,06367675 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,01995522 0,06359241 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,01995522 0,06350829 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,01995522 0,06342439 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,01995522 0,06334072 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,01995522 0,06325727 ! determination of adult lifespan GO:0008340 15 6 0,000 0,01995522 0,06317403 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,01995522 0,06309102 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,01995522 0,06300822 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,01995522 0,06292564 ! catecholamine transport GO:0051937 9 6 0,000 0,01995522 0,06284328 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,01995522 0,06276113 ! sensory cilium assembly GO:0035058 10 6 0,000 0,01995522 0,0626792 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,01995522 0,06259748 ! maternal placenta development GO:0001893 12 6 0,000 0,01995522 0,06251597 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,01995522 0,06243468 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,01995522 0,06235359 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,01995522 0,06227272 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,01995522 0,06219205 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,01995522 0,0621116 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,01995522 0,06203135 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,01995522 0,06195131 ! germ cell development GO:0007281 118 65 1,000 0,02019377 0,06261109 ! myeloid cell differentiation GO:0030099 111 65 1,000 0,02019377 0,06253051 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 1,000 0,02077992 0,06426282 ! actin filament organization GO:0007015 148 66 1,000 0,02077992 0,06418033 ! developmental maturation GO:0021700 116 66 1,000 0,02077992 0,06409805 ! cell projection assembly GO:0030031 120 66 1,000 0,02077992 0,06401598 ! regulation of cellular response to stress GO:0080135 128 67 1,000 0,02137312 0,06575924 ! negative regulation of protein kinase activity GO:0006469 130 67 1,000 0,02137312 0,06567526 ! adaptive immune response GO:0002250 119 67 1,000 0,02137312 0,06559149 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! negative regulation of kinase activity GO:0033673 131 68 1,000 0,02197333 0,06734755 ! viral reproduction GO:0016032 134 68 1,000 0,02197333 0,06726186 ! cAMP-mediated signaling GO:0019933 120 69 1,000 0,02258049 0,06903259 ! urogenital system development GO:0001655 137 69 1,000 0,02258049 0,06894499 ! tRNA transcription GO:0009304 14 7 0,000 0,02324254 0,0708765 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,02324254 0,07078679 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,02324254 0,0706973 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,02324254 0,07060803 ! regulation of helicase activity GO:0051095 15 7 0,000 0,02324254 0,07051899 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,02324254 0,07043018 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,02324254 0,07034159 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,02324254 0,07025322 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,02324254 0,07016507 ! prostate gland development GO:0030850 13 7 0,000 0,02324254 0,07007714 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,02324254 0,06998944 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,02324254 0,06990195 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,02324254 0,06981468 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,02324254 0,06972763 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,02324254 0,0696408 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,02324254 0,06955418 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,02324254 0,06946778 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 0,02324254 0,06938159 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,02324254 0,06929561 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,02324254 0,06920985 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,02324254 0,0691243 ! glycolipid transport GO:0046836 10 7 0,000 0,02324254 0,06903896 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,02324254 0,06895384 GO:0051923|sulfation, ! neuron adhesion GO:0007158 12 7 0,000 0,02324254 0,06886892 ! N-terminal protein amino acid acetylation GO:0006474 13 7 0,000 0,02324254 0,06878421 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,02324254 0,06869971 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,02324254 0,06861541 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,02324254 0,06853132 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,02324254 0,06844744 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,02324254 0,06836377 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,02324254 0,06828029 ! pericardium development GO:0060039 14 7 0,000 0,02324254 0,06819703 ! fibril organization GO:0043206 16 7 0,000 0,02324254 0,06811396 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,02324254 0,0680311 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,02324254 0,06794843 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,02324254 0,06786597 ! lipoprotein transport GO:0042953 14 7 0,000 0,02324254 0,06778371 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,02324254 0,06770165 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,02324254 0,06761978 ! rhythmic behavior GO:0007622 15 7 0,000 0,02324254 0,06753812 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,02324254 0,06745665 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,02324254 0,06737537 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,02324254 0,0672943 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,02324254 0,06721341 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,02324254 0,06713273 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,02324254 0,06705223 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,02324254 0,06697193 ! mechanosensory behavior GO:0007638 14 7 0,000 0,02324254 0,06689182 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,02324254 0,0668119 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,02324254 0,06673217 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,02324254 0,06665263 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,02324254 0,06657329 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,02324254 0,06649413 ! spinal cord patterning GO:0021511 13 7 0,000 0,02324254 0,06641516 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,02324254 0,06633637 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,02324254 0,06625777 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,02324254 0,06617936 ! adrenal gland development GO:0030325 17 7 0,000 0,02324254 0,06610114 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,02324254 0,06602309 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,02324254 0,06594524 ! ovulation GO:0030728 9 7 0,000 0,02324254 0,06586756 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,02324254 0,06579007 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,02324254 0,06571276 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,02324254 0,06563563 ! microtubule nucleation GO:0007020 20 7 0,000 0,02324254 0,06555869 ! proline biosynthetic process GO:0006561 10 7 0,000 0,02324254 0,06548192 ! thyroid hormone generation GO:0006590 13 7 0,000 0,02324254 0,06540533 ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,02324254 0,06532893 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,02324254 0,0652527 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,02324254 0,06517664 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,02324254 0,06510077 ! galactose metabolic process GO:0006012 13 7 0,000 0,02324254 0,06502507 ! vesicle fusion GO:0006906 17 7 0,000 0,02324254 0,06494955 ! response to dietary excess GO:0002021 8 7 0,000 0,02324254 0,0648742 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,02324254 0,06479903 ! intracellular pH reduction GO:0051452 11 7 0,000 0,02324254 0,06472403 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,02324254 0,0646492 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,02324254 0,06457455 ! organ growth GO:0035265 15 7 0,000 0,02324254 0,06450007 ! purine salvage GO:0043101 10 7 0,000 0,02324254 0,06442576 ! nucleoside transport GO:0015858 8 7 0,000 0,02324254 0,06435162 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,02324254 0,06427766 ! parturition GO:0007567 14 7 0,000 0,02324254 0,06420386 ! rRNA modification GO:0000154 14 7 0,000 0,02324254 0,06413023 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,02324254 0,06405677 ! spindle checkpoint GO:0031577 15 7 0,000 0,02324254 0,06398348 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,02324254 0,06391035 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,02324254 0,0638374 ! macrophage differentiation GO:0030225 11 7 0,000 0,02324254 0,06376461 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,02324254 0,06369198 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,02324254 0,06361952 GO:0046676|negative regulation of insulin secretion, ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,02324254 0,06354723 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 0,02324254 0,0634751 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,02324254 0,06340313 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,02324254 0,06333133 ! eating behavior GO:0042755 7 7 0,000 0,02324254 0,06325968 ! B cell lineage commitment GO:0002326 21 7 0,000 0,02324254 0,0631882 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,02324254 0,06311689 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,02324254 0,06304573 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,02324254 0,06297473 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,02324254 0,06290389 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,02324254 0,06283321 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,02324254 0,06276269 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,02324254 0,06269233 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,02324254 0,06262213 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,02324254 0,06255208 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,02324254 0,06248219 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,02324254 0,06241246 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,02324254 0,06234288 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,02324254 0,06227345 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,02324254 0,06220418 ! regulation of meiosis GO:0040020 12 7 0,000 0,02324254 0,06213507 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,02324254 0,0620661 ! T cell lineage commitment GO:0002360 16 7 0,000 0,02324254 0,0619973 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,02324254 0,06192864 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,02324254 0,06186013 ! oxygen homeostasis GO:0032364 12 7 0,000 0,02324254 0,06179178 ! transcription termination GO:0006353 13 7 0,000 0,02324254 0,06172358 ! response to tumor cell GO:0002347 13 7 0,000 0,02324254 0,06165552 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,02324254 0,06158762 ! anaphase GO:0051322 17 7 0,000 0,02324254 0,06151987 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,02324254 0,06145226 ! axonal fasciculation GO:0007413 18 7 0,000 0,02324254 0,06138481 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,02324254 0,0613175 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,02324254 0,06125034 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,02324254 0,06118333 ! diuresis GO:0030146 12 7 0,000 0,02324254 0,06111646 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,02324254 0,06104974 ! thiamin metabolic process GO:0006772 7 7 0,000 0,02324254 0,06098316 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,02324254 0,06091673 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,02324254 0,06085045 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,02324254 0,0607843 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,02324254 0,06071831 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,02324254 0,06065245 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,02324254 0,06058674 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,02324254 0,06052117 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,02324254 0,06045574 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,02324254 0,06039045 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,02324254 0,06032531 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,02324254 0,0602603 ! lymph node development GO:0048535 10 7 0,000 0,02324254 0,06019544 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,02324254 0,06013071 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,02324254 0,06006612 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,02324254 0,06000167 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,02324254 0,05993736 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,02324254 0,05987319 ! adult feeding behavior GO:0008343 9 7 0,000 0,02324254 0,05980916 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,02324254 0,05974526 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,02324254 0,05968149 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,02324254 0,05961787 ! embryonic heart tube development GO:0035050 10 7 0,000 0,02324254 0,05955438 ! retina homeostasis GO:0001895 12 7 0,000 0,02324254 0,05949102 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,02324254 0,0594278 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,02324254 0,05936471 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,02324254 0,05930176 ! protein prenylation GO:0018342 18 7 0,000 0,02324254 0,05923894 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,02324254 0,05917625 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,02324254 0,0591137 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,02324254 0,05905128 ! reproductive structure development GO:0048608 113 71 1,000 0,02381545 0,06044301 ! regulation of MAPKKK cascade GO:0043408 142 71 1,000 0,02381545 0,06037932 ! regulation of caspase activity GO:0043281 122 72 1,000 0,02444315 0,06190549 ! phosphoinositide metabolic process GO:0030384 128 72 1,000 0,02444315 0,0618404 ! negative regulation of transferase activity GO:0051348 140 72 1,000 0,02444315 0,06177544 ! regulation of blood pressure GO:0008217 125 73 1,000 0,02507759 0,06331237 ! axon guidance GO:0007411 139 73 1,000 0,02507759 0,063246 ! meiosis GO:0007126 121 74 1,000 0,02571873 0,06479504 GO:0051327|M phase of meiotic cell cycle, ! regulation of endopeptidase activity GO:0052548 125 74 1,000 0,02571873 0,06472726 ! cell-matrix adhesion GO:0007160 163 75 1,000 0,0263665 0,0662882 ! meiotic cell cycle GO:0051321 122 75 1,000 0,0263665 0,06621901 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,02651895 0,06653242 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,02651895 0,06646311 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,02651895 0,06639395 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,02651895 0,06632493 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,02651895 0,06625606 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,02651895 0,06618733 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,02651895 0,06611874 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,02651895 0,0660503 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,02651895 0,06598199 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,02651895 0,06591383 ! meiotic prophase I GO:0007128 13 8 0,000 0,02651895 0,06584581 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,02651895 0,06577792 ! oligopeptide transport GO:0006857 15 8 0,000 0,02651895 0,06571018 ! UTP metabolic process GO:0046051 8 8 0,000 0,02651895 0,06564258 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,02651895 0,06557511 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,02651895 0,06550779 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,02651895 0,0654406 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,02651895 0,06537355 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,02651895 0,06530664 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,02651895 0,06523986 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,02651895 0,06517322 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,02651895 0,06510672 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,02651895 0,06504035 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,02651895 0,06497412 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,02651895 0,06490802 ! reflex GO:0060004 16 8 0,000 0,02651895 0,06484206 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,02651895 0,06477623 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,02651895 0,06471053 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,02651895 0,06464497 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,02651895 0,06457954 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,02651895 0,06451424 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,02651895 0,06444908 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,02651895 0,06438404 ! pigment granule organization GO:0048753 16 8 0,000 0,02651895 0,06431914 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,02651895 0,06425437 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,02651895 0,06418973 ! astrocyte differentiation GO:0048708 18 8 0,000 0,02651895 0,06412521 ! histidine metabolic process GO:0006547 16 8 0,000 0,02651895 0,06406083 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,02651895 0,06399658 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,02651895 0,06393245 ! glycine catabolic process GO:0006546 13 8 0,000 0,02651895 0,06386846 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,02651895 0,06380459 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,02651895 0,06374085 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,02651895 0,06367723 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,02651895 0,06361375 ! melanin metabolic process GO:0006582 15 8 0,000 0,02651895 0,06355039 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,02651895 0,06348715 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,02651895 0,06342404 ! macrophage activation GO:0042116 12 8 0,000 0,02651895 0,06336106 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,02651895 0,0632982 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,02651895 0,06323547 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,02651895 0,06317286 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,02651895 0,06311037 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,02651895 0,06304801 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,02651895 0,06298577 ! osteoblast development GO:0002076 16 8 0,000 0,02651895 0,06292366 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,02651895 0,06286166 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,02651895 0,06279979 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,02651895 0,06273804 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,02651895 0,06267641 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,02651895 0,0626149 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,02651895 0,06255352 ! response to UV-B GO:0010224 16 8 0,000 0,02651895 0,06249225 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,02651895 0,0624311 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,02651895 0,06237008 ! intermediate filament organization GO:0045109 12 8 0,000 0,02651895 0,06230917 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,02651895 0,06224838 ! cellular extravasation GO:0045123 12 8 0,000 0,02651895 0,06218771 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,02651895 0,06212715 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,02651895 0,06206672 ! response to antibiotic GO:0046677 11 8 0,000 0,02651895 0,0620064 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,02651895 0,0619462 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,02651895 0,06188612 ! DNA topological change GO:0006265 12 8 0,000 0,02651895 0,06182615 ! response to tropane GO:0014073 15 8 0,000 0,02651895 0,0617663 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,02651895 0,06170656 ! melanosome transport GO:0032402 13 8 0,000 0,02651895 0,06164694 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,02651895 0,06158744 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,02651895 0,06152805 ! mast cell activation GO:0045576 14 8 0,000 0,02651895 0,06146877 ! multicellular organismal aging GO:0010259 18 8 0,000 0,02651895 0,06140961 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,02651895 0,06135056 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,02651895 0,06129163 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,02651895 0,06123281 ! nucleosome disassembly GO:0006337 14 8 0,000 0,02651895 0,0611741 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,02651895 0,0611155 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,02651895 0,06105702 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,02651895 0,06099865 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,02651895 0,06094039 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,02651895 0,06088224 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,02651895 0,0608242 ! intracellular lipid transport GO:0032365 13 8 0,000 0,02651895 0,06076627 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,02651895 0,06070846 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,02651895 0,06065075 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,02651895 0,06059315 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,02651895 0,06053566 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,02651895 0,06047828 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,02651895 0,06042101 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,02651895 0,06036385 ! hormone catabolic process GO:0042447 17 8 0,000 0,02651895 0,06030679 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,02651895 0,06024985 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,02651895 0,06019301 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,02651895 0,06013627 ! ATP catabolic process GO:0006200 11 8 0,000 0,02651895 0,06007965 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,02651895 0,06002313 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,02651895 0,05996672 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,02651895 0,05991041 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,02651895 0,05985421 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,02651895 0,05979811 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,02651895 0,05974212 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,02651895 0,05968624 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,02651895 0,05963046 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,02651895 0,05957478 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,02651895 0,0595192 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,02651895 0,05946373 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,02651895 0,05940837 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,02651895 0,0593531 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,02651895 0,05929794 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,02651895 0,05924288 GO:0000076|DNA replication checkpoint, ! NAD biosynthetic process GO:0009435 13 8 0,000 0,02651895 0,05918793 ! development of primary sexual characteristics GO:0045137 124 76 1,000 0,02702087 0,06025229 ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 1,000 0,02834917 0,06315566 ! response to steroid hormone stimulus GO:0048545 137 78 1,000 0,02834917 0,06309724 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 1,000 0,02902301 0,0645373 ! regulation of peptidase activity GO:0052547 134 79 1,000 0,02902301 0,06447771 ! regulation of adenylate cyclase activity GO:0045761 156 80 1,000 0,02970323 0,06592803 ! muscle cell differentiation GO:0042692 159 80 1,000 0,02970323 0,06586726 ! axon extension GO:0048675 15 9 0,000 0,02978447 0,06598659 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,02978447 0,06592588 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,02978447 0,06586529 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,02978447 0,0658048 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,02978447 0,06574443 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,02978447 0,06568417 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,02978447 0,06562402 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,02978447 0,06556398 ! phosphate transport GO:0006817 19 9 0,000 0,02978447 0,06550405 ! reproductive behavior GO:0019098 19 9 0,000 0,02978447 0,06544423 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,02978447 0,06538452 ! CTP metabolic process GO:0046036 9 9 0,000 0,02978447 0,06532491 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,02978447 0,06526542 ! GTP metabolic process GO:0046039 9 9 0,000 0,02978447 0,06520603 ! RNA methylation GO:0001510 15 9 0,000 0,02978447 0,06514676 ! elastic fiber assembly GO:0048251 15 9 0,000 0,02978447 0,06508759 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,02978447 0,06502852 ! artery development GO:0060840 24 9 0,000 0,02978447 0,06496957 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,02978447 0,06491072 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,02978447 0,06485197 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,02978447 0,06479334 ! chemosensory behavior GO:0007635 20 9 0,000 0,02978447 0,06473481 ! microtubule bundle formation GO:0001578 21 9 0,000 0,02978447 0,06467638 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,02978447 0,06461806 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,02978447 0,06455985 ! leukocyte degranulation GO:0043299 16 9 0,000 0,02978447 0,06450174 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,02978447 0,06444373 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,02978447 0,06438583 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,02978447 0,06432804 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,02978447 0,06427034 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,02978447 0,06421275 ! protein targeting to ER GO:0045047 22 9 0,000 0,02978447 0,06415527 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,02978447 0,06409788 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,02978447 0,0640406 ! T cell selection GO:0045058 23 9 0,000 0,02978447 0,06398342 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,02978447 0,06392634 ! endosome organization GO:0007032 17 9 0,000 0,02978447 0,06386937 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,02978447 0,06381249 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,02978447 0,06375572 ! mannose metabolic process GO:0006013 13 9 0,000 0,02978447 0,06369905 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,02978447 0,06364248 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,02978447 0,06358601 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,02978447 0,06352964 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,02978447 0,06347337 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,02978447 0,0634172 ! ruffle organization GO:0031529 15 9 0,000 0,02978447 0,06336112 ! retinol metabolic process GO:0042572 18 9 0,000 0,02978447 0,06330515 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,02978447 0,06324928 ! behavioral fear response GO:0001662 22 9 0,000 0,02978447 0,0631935 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,02978447 0,06313783 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,02978447 0,06308225 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,02978447 0,06302676 GO:0030204|chondroitin sulfate metabolic process, ! oligodendrocyte development GO:0014003 10 9 0,000 0,02978447 0,06297138 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,02978447 0,06291609 ! segment specification GO:0007379 13 9 0,000 0,02978447 0,0628609 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,02978447 0,06280581 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,02978447 0,06275082 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,02978447 0,06269592 ! response to amine stimulus GO:0014075 13 9 0,000 0,02978447 0,06264111 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,02978447 0,0625864 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,02978447 0,06253179 ! erythrocyte development GO:0048821 15 9 0,000 0,02978447 0,06247727 ! gas homeostasis GO:0033483 16 9 0,000 0,02978447 0,06242285 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,02978447 0,06236852 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,02978447 0,06231429 ! renal water homeostasis GO:0003091 14 9 0,000 0,02978447 0,06226015 ! postreplication repair GO:0006301 22 9 0,000 0,02978447 0,0622061 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,02978447 0,06215215 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,02978447 0,06209829 ! icosanoid secretion GO:0032309 15 9 0,000 0,02978447 0,06204453 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,02978447 0,06199086 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,02978447 0,06193728 ! regulation of cell division GO:0051302 15 9 0,000 0,02978447 0,06188379 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,02978447 0,0618304 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,02978447 0,0617771 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,02978447 0,06172389 ! sterol catabolic process GO:0016127 11 9 0,000 0,02978447 0,06167077 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,02978447 0,06161774 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,02978447 0,0615648 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,02978447 0,06151196 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,02978447 0,0614592 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,02978447 0,06140654 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,02978447 0,06135397 ! musculoskeletal movement GO:0050881 14 9 0,000 0,02978447 0,06130148 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,02978447 0,06124909 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,02978447 0,06119678 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,02978447 0,06114457 ! purine base metabolic process GO:0006144 21 9 0,000 0,02978447 0,06109244 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,02978447 0,0610404 ! pigment granule transport GO:0051904 17 9 0,000 0,02978447 0,06098845 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,02978447 0,06093659 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,02978447 0,06088482 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,02978447 0,06083313 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,02978447 0,06078154 ! mitochondrion localization GO:0051646 15 9 0,000 0,02978447 0,06073003 ! cell-substrate adhesion GO:0031589 171 81 1,000 0,0303898 0,06191182 ! regulation of cAMP biosynthetic process GO:0030817 161 82 1,000 0,03108265 0,06326977 ! cholesterol metabolic process GO:0008203 136 82 1,000 0,03108265 0,06321629 ! regulation of cyclase activity GO:0031279 159 82 1,000 0,03108265 0,06316289 ! regulation of lyase activity GO:0051339 160 83 1,000 0,03178175 0,06452902 ! regulation of cAMP metabolic process GO:0030814 168 84 1,000 0,03248704 0,06590542 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 0,000 0,03303914 0,06696898 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,03303914 0,06691261 ! positive regulation of B cell proliferation GO:0030890 16 10 0,000 0,03303914 0,06685633 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,03303914 0,06680015 ! synapsis GO:0007129 13 10 0,000 0,03303914 0,06674406 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,03303914 0,06668807 ! N-glycan processing GO:0006491 20 10 0,000 0,03303914 0,06663217 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,03303914 0,06657637 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,03303914 0,06652065 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,03303914 0,06646503 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,03303914 0,06640951 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,03303914 0,06635407 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,03303914 0,06629873 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,03303914 0,06624348 ! androgen metabolic process GO:0008209 17 10 0,000 0,03303914 0,06618833 ! phospholipid efflux GO:0033700 16 10 0,000 0,03303914 0,06613326 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,03303914 0,06607829 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,03303914 0,06602341 ! pathogenesis GO:0009405 13 10 0,000 0,03303914 0,06596861 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,03303914 0,06591391 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,03303914 0,0658593 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,03303914 0,06580479 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,03303914 0,06575036 ! endoderm development GO:0007492 16 10 0,000 0,03303914 0,06569602 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,03303914 0,06564177 ! arginine catabolic process GO:0006527 13 10 0,000 0,03303914 0,06558761 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,03303914 0,06553354 ! proline metabolic process GO:0006560 13 10 0,000 0,03303914 0,06547956 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,03303914 0,06542566 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,03303914 0,06537186 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,03303914 0,06531814 ! V(D)J recombination GO:0033151 28 10 0,000 0,03303914 0,06526452 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,03303914 0,06521098 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,03303914 0,06515753 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,03303914 0,06510416 ! B cell proliferation GO:0042100 18 10 0,000 0,03303914 0,06505088 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,03303914 0,06499769 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,03303914 0,06494459 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,03303914 0,06489158 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,03303914 0,06483865 ! epithelial cell development GO:0002064 20 10 0,000 0,03303914 0,0647858 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,03303914 0,06473305 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,03303914 0,06468037 ! macroautophagy GO:0016236 17 10 0,000 0,03303914 0,06462779 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,03303914 0,06457529 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,03303914 0,06452287 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,03303914 0,06447054 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,03303914 0,0644183 ! copper ion homeostasis GO:0055070 13 10 0,000 0,03303914 0,06436614 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,03303914 0,06431406 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,03303914 0,06426207 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,03303914 0,06421016 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,03303914 0,06415834 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,03303914 0,0641066 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,03303914 0,06405494 ! blastoderm segmentation GO:0007350 18 10 0,000 0,03303914 0,06400337 ! response to dsRNA GO:0043331 20 10 0,000 0,03303914 0,06395188 ! DNA ligation GO:0006266 19 10 0,000 0,03303914 0,06390047 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,03303914 0,06384914 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,03303914 0,0637979 ! melanosome localization GO:0032400 16 10 0,000 0,03303914 0,06374674 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,03303914 0,06369566 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,03303914 0,06364466 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,03303914 0,06359374 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,03303914 0,06354291 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,03303914 0,06349216 ! mRNA cleavage GO:0006379 17 10 0,000 0,03303914 0,06344149 ! protein sumoylation GO:0016925 15 10 0,000 0,03303914 0,06339089 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,03303914 0,06334038 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,03303914 0,06328995 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,03303914 0,0632396 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,03303914 0,06318933 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,03303914 0,06313914 ! salivary gland development GO:0007431 27 10 0,000 0,03303914 0,06308903 ! prophase GO:0051324 15 10 0,000 0,03303914 0,063039 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,03303914 0,06298905 ! apical protein localization GO:0045176 15 10 0,000 0,03303914 0,06293918 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,03303914 0,06288938 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,03303914 0,06283967 ! midbrain development GO:0030901 13 10 0,000 0,03303914 0,06279003 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,03303914 0,06274047 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,03303914 0,06269099 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,03303914 0,06264159 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,03303914 0,06259227 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,03303914 0,06254302 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,03303914 0,06249385 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,03303914 0,06244476 ! detection of calcium ion GO:0005513 23 10 0,000 0,03303914 0,06239575 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,03303914 0,06234681 ! blastocyst formation GO:0001825 17 10 0,000 0,03303914 0,06229795 ! cerebellar cortex development GO:0021695 15 10 0,000 0,03303914 0,06224916 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,03303914 0,06220045 ! activation of innate immune response GO:0002218 12 10 0,000 0,03303914 0,06215182 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,03303914 0,06210327 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,03303914 0,06205479 ! response to nicotine GO:0035094 20 10 0,000 0,03303914 0,06200638 ! establishment of cell polarity GO:0030010 16 10 0,000 0,03303914 0,06195805 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,03303914 0,0619098 ! one-carbon metabolic process GO:0006730 154 85 1,000 0,03319848 0,06215995 ! tube morphogenesis GO:0035239 176 86 1,000 0,03391601 0,06345406 ! mitochondrion organization GO:0007005 148 86 1,000 0,03391601 0,06340475 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 1,000 0,03463959 0,06470718 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! regulation of cell morphogenesis GO:0022604 215 89 1,000 0,0361047 0,06739171 ! regulation of cell adhesion GO:0030155 212 89 1,000 0,0361047 0,06733947 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,03628301 0,06761961 ! respiratory burst GO:0045730 17 11 0,000 0,03628301 0,06756728 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,03628301 0,06751502 ! neuron fate specification GO:0048665 17 11 0,000 0,03628301 0,06746284 ! telencephalon cell migration GO:0022029 20 11 0,000 0,03628301 0,06741075 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,03628301 0,06735873 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,03628301 0,0673068 ! thyroid gland development GO:0030878 26 11 0,000 0,03628301 0,06725495 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,03628301 0,06720317 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,03628301 0,06715148 ! response to pain GO:0048265 24 11 0,000 0,03628301 0,06709986 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,03628301 0,06704833 ! T cell proliferation GO:0042098 26 11 0,000 0,03628301 0,06699687 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,03628301 0,06694549 GO:0010812|negative regulation of cell-substrate adhesion, ! bone resorption GO:0045453 16 11 0,000 0,03628301 0,06689419 ! peptide or protein amino-terminal blocking GO:0018409 21 11 0,000 0,03628301 0,06684297 ! ventral spinal cord development GO:0021517 21 11 0,000 0,03628301 0,06679183 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,03628301 0,06674076 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,03628301 0,06668978 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,03628301 0,06663887 ! melanocyte differentiation GO:0030318 21 11 0,000 0,03628301 0,06658804 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,03628301 0,06653729 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,03628301 0,06648661 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,03628301 0,06643601 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,03628301 0,06638549 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,03628301 0,06633505 ! lipid digestion GO:0044241 18 11 0,000 0,03628301 0,06628468 ! UV protection GO:0009650 19 11 0,000 0,03628301 0,06623439 ! adult heart development GO:0007512 14 11 0,000 0,03628301 0,06618417 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,03628301 0,06613403 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,03628301 0,06608397 ! temperature homeostasis GO:0001659 17 11 0,000 0,03628301 0,06603398 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,03628301 0,06598407 ! negative regulation of ossification GO:0030279 26 11 0,000 0,03628301 0,06593423 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,03628301 0,06588447 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,03628301 0,06583478 ! regulation of organ growth GO:0046620 13 11 0,000 0,03628301 0,06578517 ! pigment granule localization GO:0051875 20 11 0,000 0,03628301 0,06573563 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,03628301 0,06568617 ! vasoconstriction GO:0042310 18 11 0,000 0,03628301 0,06563678 ! embryonic axis specification GO:0000578 18 11 0,000 0,03628301 0,06558747 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,03628301 0,06553823 ! snRNA metabolic process GO:0016073 24 11 0,000 0,03628301 0,06548906 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,03628301 0,06543997 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,03628301 0,06539095 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,03628301 0,06534201 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,03628301 0,06529313 ! zymogen activation GO:0031638 15 11 0,000 0,03628301 0,06524433 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,03628301 0,06519561 ! neuroblast proliferation GO:0007405 24 11 0,000 0,03628301 0,06514696 ! nucleosome positioning GO:0016584 15 11 0,000 0,03628301 0,06509837 ! regulation of isotype switching GO:0045191 22 11 0,000 0,03628301 0,06504987 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,03628301 0,06500143 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,03628301 0,06495307 ! acid secretion GO:0046717 18 11 0,000 0,03628301 0,06490477 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,03628301 0,06485655 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,03628301 0,0648084 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,03628301 0,06476033 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,03628301 0,06471232 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,03628301 0,06466439 ! cholesterol efflux GO:0033344 19 11 0,000 0,03628301 0,06461652 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,03628301 0,06456873 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,03628301 0,06452101 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,03628301 0,06447335 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,03628301 0,06442577 ! embryonic gut development GO:0048566 15 11 0,000 0,03628301 0,06437826 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,03628301 0,06433082 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,03628301 0,06428345 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,03628301 0,06423614 ! defense response to fungus GO:0050832 13 11 0,000 0,03628301 0,06418891 ! lysogeny GO:0030069 21 11 0,000 0,03628301 0,06414175 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,03628301 0,06409466 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,03628301 0,06404763 ! sequestering of metal ion GO:0051238 14 11 0,000 0,03628301 0,06400067 ! lamellipodium assembly GO:0030032 20 11 0,000 0,03628301 0,06395379 ! nucleus localization GO:0051647 19 11 0,000 0,03628301 0,06390697 ! regulation of synapse organization GO:0050807 17 11 0,000 0,03628301 0,06386022 ! ossification GO:0001503 188 90 1,000 0,03684614 0,06480396 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 1,000 0,03684614 0,06475662 ! sex differentiation GO:0007548 145 90 1,000 0,03684614 0,06470935 ! bone development GO:0060348 189 91 1,000 0,03759344 0,06597361 ! sterol metabolic process GO:0016125 152 91 1,000 0,03759344 0,06592552 ! regulation of defense response GO:0031347 149 92 1,000 0,03834655 0,06719723 ! vitamin metabolic process GO:0006766 139 92 1,000 0,03834655 0,06714832 ! regulation of nucleotide metabolic process GO:0006140 182 93 1,000 0,03910542 0,06842738 ! regulation of membrane potential GO:0042391 164 93 1,000 0,03910542 0,06837765 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,0395161 0,06904556 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,0395161 0,06899545 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,0395161 0,06894542 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,0395161 0,06889546 ! regulation of B cell proliferation GO:0030888 20 12 0,000 0,0395161 0,06884557 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,0395161 0,06879576 ! cartilage condensation GO:0001502 20 12 0,000 0,0395161 0,06874601 ! mating GO:0007618 17 12 0,000 0,0395161 0,06869634 ! protein complex disassembly GO:0043241 27 12 0,000 0,0395161 0,06864674 GO:0043624|cellular protein complex disassembly, ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,0395161 0,06859721 ! hippocampus development GO:0021766 26 12 0,000 0,0395161 0,06854775 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,0395161 0,06849837 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,0395161 0,06844905 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,0395161 0,06839981 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,0395161 0,06835064 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,0395161 0,06830153 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,0395161 0,0682525 ! drug transport GO:0015893 16 12 0,000 0,0395161 0,06820354 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,0395161 0,06815465 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,0395161 0,06810583 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,0395161 0,06805708 ! polyamine metabolic process GO:0006595 17 12 0,000 0,0395161 0,06800839 ! focal adhesion formation GO:0048041 35 12 0,000 0,0395161 0,06795978 ! mitotic spindle organization GO:0007052 21 12 0,000 0,0395161 0,06791124 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,0395161 0,06786277 ! forebrain cell migration GO:0021885 21 12 0,000 0,0395161 0,06781436 ! asymmetric protein localization GO:0008105 20 12 0,000 0,0395161 0,06776603 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,0395161 0,06771776 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,0395161 0,06766956 ! entry into host cell GO:0030260 32 12 0,000 0,0395161 0,06762143 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,0395161 0,06757337 ! monoamine transport GO:0015844 18 12 0,000 0,0395161 0,06752538 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,0395161 0,06747746 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,0395161 0,0674296 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,0395161 0,06738181 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,0395161 0,06733409 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,0395161 0,06728644 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,0395161 0,06723885 ! protein homotetramerization GO:0051289 21 12 0,000 0,0395161 0,06719133 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,0395161 0,06714388 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,0395161 0,0670965 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,0395161 0,06704918 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,0395161 0,06700193 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,0395161 0,06695474 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,0395161 0,06690763 ! cranial nerve development GO:0021545 20 12 0,000 0,0395161 0,06686057 ! fucose catabolic process GO:0019317 22 12 0,000 0,0395161 0,06681359 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,0395161 0,06676667 ! histone methylation GO:0016571 26 12 0,000 0,0395161 0,06671981 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,0395161 0,06667303 ! autonomic nervous system development GO:0048483 24 12 0,000 0,0395161 0,0666263 ! gland morphogenesis GO:0022612 29 12 0,000 0,0395161 0,06657965 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,0395161 0,06653305 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,0395161 0,06648653 ! T cell homeostasis GO:0043029 25 12 0,000 0,0395161 0,06644007 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,0395161 0,06639367 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,0395161 0,06634734 ! spleen development GO:0048536 22 12 0,000 0,0395161 0,06630107 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,0395161 0,06625487 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,0395161 0,06620873 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,0395161 0,06616266 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,0395161 0,06611664 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,0395161 0,0660707 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,0395161 0,06602482 ! response to cold GO:0009409 17 12 0,000 0,0395161 0,065979 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,0395161 0,06593324 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,0395161 0,06588755 ! transcription initiation GO:0006352 153 94 1,000 0,03987002 0,06643162 ! regulation of T cell activation GO:0050863 158 94 1,000 0,03987002 0,06638565 ! interphase of mitotic cell cycle GO:0051329 209 95 1,000 0,04064029 0,06762139 ! protein ubiquitination GO:0016567 217 97 1,000 0,04219766 0,07016418 ! cGMP metabolic process GO:0046068 18 13 0,000 0,04273845 0,0710143 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,04273845 0,07096529 ! regulation of chemokine production GO:0032642 18 13 0,000 0,04273845 0,07091635 ! peroxisomal transport GO:0043574 24 13 0,000 0,04273845 0,07086748 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,04273845 0,07081867 ! lipid localization GO:0010876 28 13 0,000 0,04273845 0,07076993 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,04273845 0,07072126 ! organelle fusion GO:0048284 32 13 0,000 0,04273845 0,07067265 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,04273845 0,07062412 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,04273845 0,07057564 ! endocrine pancreas development GO:0031018 22 13 0,000 0,04273845 0,07052724 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,04273845 0,0704789 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,04273845 0,07043062 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,04273845 0,07038242 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,04273845 0,07033428 ! methionine metabolic process GO:0006555 27 13 0,000 0,04273845 0,0702862 ! plasma membrane organization GO:0007009 24 13 0,000 0,04273845 0,07023819 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,04273845 0,07019025 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,04273845 0,07014237 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,04273845 0,07009455 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,04273845 0,07004681 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,04273845 0,06999912 ! cytokine metabolic process GO:0042107 22 13 0,000 0,04273845 0,0699515 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,04273845 0,06990395 ! exocrine system development GO:0035272 32 13 0,000 0,04273845 0,06985646 ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,04273845 0,06980904 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,04273845 0,06976168 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,04273845 0,06971438 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,04273845 0,06966715 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,04273845 0,06961998 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,04273845 0,06957288 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,04273845 0,06952584 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,04273845 0,06947886 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,04273845 0,06943195 ! regulation of cellular pH GO:0030641 22 13 0,000 0,04273845 0,0693851 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,04273845 0,06933831 ! ribosome assembly GO:0042255 17 13 0,000 0,04273845 0,06929158 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,04273845 0,06924492 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,04273845 0,06919833 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,04273845 0,06915179 ! regulation of epidermis development GO:0045682 19 13 0,000 0,04273845 0,06910532 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,04273845 0,06905891 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,04273845 0,06901256 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,04273845 0,06896627 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,04273845 0,06892005 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,04273845 0,06887389 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,04273845 0,06882779 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,04273845 0,06878175 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,04273845 0,06873577 ! embryonic placenta development GO:0001892 23 13 0,000 0,04273845 0,06868985 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,04273845 0,068644 ! insulin secretion GO:0030073 23 13 0,000 0,04273845 0,06859821 ! actin filament polymerization GO:0030041 24 13 0,000 0,04273845 0,06855247 ! acrosome reaction GO:0007340 18 13 0,000 0,04273845 0,0685068 ! interphase GO:0051325 213 98 1,000 0,04298467 0,0688556 ! skeletal muscle tissue development GO:0007519 186 99 1,000 0,04377717 0,07007843 GO:0060538|skeletal muscle organ development, ! rRNA transcription GO:0009303 25 14 0,000 0,0459501 0,07350793 ! lactation GO:0007595 26 14 0,000 0,0459501 0,07345909 ! N-terminal protein amino acid modification GO:0031365 27 14 0,000 0,0459501 0,07341031 ! reproductive cellular process GO:0048610 20 14 0,000 0,0459501 0,0733616 ! tRNA modification GO:0006400 20 14 0,000 0,0459501 0,07331295 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,0459501 0,07326437 ! water transport GO:0006833 21 14 0,000 0,0459501 0,07321585 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,0459501 0,0731674 ! non-recombinational repair GO:0000726 25 14 0,000 0,0459501 0,073119 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,0459501 0,07307068 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,0459501 0,07302241 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,0459501 0,07297421 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,0459501 0,07292608 ! RNA polyadenylation GO:0043631 30 14 0,000 0,0459501 0,07287801 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,0459501 0,07283 ! palate development GO:0060021 31 14 0,000 0,0459501 0,07278205 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,0459501 0,07273417 ! regulated secretory pathway GO:0045055 23 14 0,000 0,0459501 0,07268635 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,0459501 0,07263859 ! arginine metabolic process GO:0006525 17 14 0,000 0,0459501 0,0725909 ! regulation of heart rate GO:0002027 24 14 0,000 0,0459501 0,07254326 ! organic alcohol transport GO:0015850 29 14 0,000 0,0459501 0,07249569 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,0459501 0,07244819 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,0459501 0,07240074 ! neutral amino acid transport GO:0015804 26 14 0,000 0,0459501 0,07235336 ! L-amino acid transport GO:0015807 30 14 0,000 0,0459501 0,07230604 ! bone mineralization GO:0030282 17 14 0,000 0,0459501 0,07225878 ! stem cell development GO:0048864 43 14 0,000 0,0459501 0,07221158 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,0459501 0,07216445 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,0459501 0,07211737 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,0459501 0,07207036 ! cerebellum development GO:0021549 21 14 0,000 0,0459501 0,07202341 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,0459501 0,07197652 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,0459501 0,07192969 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,0459501 0,07188292 ! cofactor transport GO:0051181 26 14 0,000 0,0459501 0,07183621 ! NADP metabolic process GO:0006739 24 14 0,000 0,0459501 0,07178957 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,0459501 0,07174298 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,0459501 0,07169646 ! intestinal absorption GO:0050892 25 14 0,000 0,0459501 0,07164999 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,0459501 0,07160358 ! oxygen transport GO:0015671 21 14 0,000 0,0459501 0,07155724 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,0459501 0,07151095 ! male genitalia development GO:0030539 24 14 0,000 0,0459501 0,07146473 ! regulation of axon extension GO:0030516 37 14 0,000 0,0459501 0,07141856 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,0459501 0,07137246 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,04915108 0,07629515 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,04915108 0,07624596 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! superoxide anion generation GO:0042554 20 15 0,000 0,04915108 0,07619683 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,04915108 0,07614777 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,04915108 0,07609877 ! copper ion transport GO:0006825 20 15 0,000 0,04915108 0,07604983 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,04915108 0,07600096 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,04915108 0,07595214 ! sulfate transport GO:0008272 23 15 0,000 0,04915108 0,07590339 ! response to cAMP GO:0051591 22 15 0,000 0,04915108 0,07585471 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,04915108 0,07580608 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,04915108 0,07575752 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,04915108 0,07570902 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,04915108 0,07566058 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,04915108 0,0756122 ! response to hexose stimulus GO:0009746 22 15 0,000 0,04915108 0,07556389 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,04915108 0,07551564 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,04915108 0,07546745 ! pituitary gland development GO:0021983 29 15 0,000 0,04915108 0,07541932 ! vesicle coating GO:0006901 33 15 0,000 0,04915108 0,07537125 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,04915108 0,07532324 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,04915108 0,07527529 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,04915108 0,07522741 ! regulation of exocytosis GO:0017157 22 15 0,000 0,04915108 0,07517958 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,04915108 0,07513182 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,04915108 0,07508412 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,04915108 0,07503648 ! regulation of vasodilation GO:0042312 26 15 0,000 0,04915108 0,07498889 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,04915108 0,07494137 ! histone deacetylation GO:0016575 20 15 0,000 0,04915108 0,07489391 ! mRNA splice site selection GO:0006376 38 15 0,000 0,04915108 0,07484651 ! tissue regeneration GO:0042246 26 15 0,000 0,04915108 0,07479917 ! water homeostasis GO:0030104 27 15 0,000 0,04915108 0,07475189 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,04915108 0,07470467 ! muscle maintenance GO:0046716 26 15 0,000 0,04915108 0,0746575 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,04915108 0,0746104 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,04915108 0,07456336 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,04915108 0,07451637 ! dopamine metabolic process GO:0042417 35 15 0,000 0,04915108 0,07446945 ! heme biosynthetic process GO:0006783 29 15 0,000 0,04915108 0,07442258 ! cell killing GO:0001906 29 15 0,000 0,04915108 0,07437578 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,04915108 0,07432903 ! detection of bacterium GO:0016045 18 15 0,000 0,04915108 0,07428234 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,04915108 0,07423571 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,04915108 0,07418914 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,04915108 0,07414263 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,04915108 0,07409617 ! peptide hormone processing GO:0016486 23 15 0,000 0,04915108 0,07404977 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,05234142 0,07880692 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,05234142 0,07875763 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,05234142 0,07870841 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,05234142 0,07865925 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,05234142 0,07861015 ! bone remodeling GO:0046849 27 16 0,000 0,05234142 0,07856111 ! filopodium assembly GO:0046847 32 16 0,000 0,05234142 0,07851213 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,05234142 0,07846321 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,05234142 0,07841436 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,05234142 0,07836556 ! startle response GO:0001964 28 16 0,000 0,05234142 0,07831683 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,05234142 0,07826815 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,05234142 0,07821954 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,05234142 0,07817098 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,05234142 0,07812249 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,05234142 0,07807406 ! protein polyubiquitination GO:0000209 34 16 0,000 0,05234142 0,07802568 ! glutamate metabolic process GO:0006536 22 16 0,000 0,05234142 0,07797737 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,05234142 0,07792912 ! response to osmotic stress GO:0006970 25 16 0,000 0,05234142 0,07788092 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,05234142 0,07783279 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,05234142 0,07778472 ! fructose metabolic process GO:0006000 25 16 0,000 0,05234142 0,0777367 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,05234142 0,07768874 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,05234142 0,07764085 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,05234142 0,07759301 ! negative regulation of immune response GO:0050777 35 16 0,000 0,05234142 0,07754523 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,05234142 0,07749751 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,05234142 0,07744985 ! DNA replication initiation GO:0006270 27 16 0,000 0,05234142 0,07740225 ! neuron recognition GO:0008038 35 16 0,000 0,05234142 0,0773547 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,05234142 0,07730722 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,05234142 0,07725979 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,05234142 0,07721242 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,05234142 0,07716511 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,05234142 0,07711785 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,05234142 0,07707066 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,05234142 0,07702352 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,05234142 0,07697644 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,05234142 0,07692942 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,05234142 0,07688245 ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,05234142 0,07683554 ! defense response to virus GO:0051607 37 16 0,000 0,05234142 0,07678869 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,05552116 0,08140397 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,05552116 0,0813544 ! metencephalon development GO:0022037 30 17 0,000 0,05552116 0,08130488 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,05552116 0,08125543 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,05552116 0,08120603 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,05552116 0,0811567 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,05552116 0,08110742 ! endothelial cell migration GO:0043542 28 17 0,000 0,05552116 0,08105821 ! inositol metabolic process GO:0006020 28 17 0,000 0,05552116 0,08100905 ! gene silencing by RNA GO:0031047 36 17 0,000 0,05552116 0,08095995 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,05552116 0,08091092 ! glial cell development GO:0021782 27 17 0,000 0,05552116 0,08086194 ! limbic system development GO:0021761 36 17 0,000 0,05552116 0,08081302 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,05552116 0,08076416 ! adult walking behavior GO:0007628 33 17 0,000 0,05552116 0,08071536 ! heart looping GO:0001947 30 17 0,000 0,05552116 0,08066662 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,05552116 0,08061794 ! myoblast differentiation GO:0045445 45 17 0,000 0,05552116 0,08056931 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,05552116 0,08052075 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,05552116 0,08047224 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,05552116 0,08042379 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,05552116 0,0803754 ! glycine metabolic process GO:0006544 28 17 0,000 0,05552116 0,08032707 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,05552116 0,0802788 ! NAD metabolic process GO:0019674 29 17 0,000 0,05552116 0,08023058 ! membrane budding GO:0006900 37 17 0,000 0,05552116 0,08018243 ! DNA integration GO:0015074 29 17 0,000 0,05552116 0,08013433 ! regulation of protein binding GO:0043393 33 17 0,000 0,05552116 0,08008628 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,05552116 0,0800383 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,05552116 0,07999037 ! genitalia development GO:0048806 30 17 0,000 0,05552116 0,0799425 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,05552116 0,07989469 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,05552116 0,07984694 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,05552116 0,07979924 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,05552116 0,0797516 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,05552116 0,07970401 ! steroid catabolic process GO:0006706 31 17 0,000 0,05552116 0,07965648 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,05552116 0,07960901 ! gas transport GO:0015669 25 17 0,000 0,05552116 0,0795616 ! organic cation transport GO:0015695 31 17 0,000 0,05552116 0,07951424 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,05552116 0,07946694 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,05552116 0,07941969 ! microspike assembly GO:0030035 36 17 0,000 0,05552116 0,0793725 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,05552116 0,07932537 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,05552116 0,07927829 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,05869035 0,08375384 ! neuron maturation GO:0042551 42 18 0,000 0,05869035 0,08370419 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,05869035 0,0836546 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,05869035 0,08360508 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,05869035 0,08355561 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,05869035 0,08350619 ! memory GO:0007613 31 18 0,000 0,05869035 0,08345684 ! negative regulation of ion transport GO:0043271 24 18 0,000 0,05869035 0,08340754 ! patterning of blood vessels GO:0001569 39 18 0,000 0,05869035 0,08335831 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,05869035 0,08330913 GO:0042744|hydrogen peroxide catabolic process, ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,05869035 0,08326001 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,05869035 0,08321094 ! glutamine metabolic process GO:0006541 29 18 0,000 0,05869035 0,08316194 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,05869035 0,08311299 ! response to fungus GO:0009620 21 18 0,000 0,05869035 0,0830641 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,05869035 0,08301527 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,05869035 0,08296649 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,05869035 0,08291778 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,05869035 0,08286912 ! vitamin transport GO:0051180 27 18 0,000 0,05869035 0,08282051 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,05869035 0,08277197 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,05869035 0,08272348 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,05869035 0,08267504 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,05869035 0,08262667 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,05869035 0,08257835 ! nerve development GO:0021675 28 18 0,000 0,05869035 0,08253008 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,05869035 0,08248188 ! protein secretion GO:0009306 39 19 0,000 0,061849 0,08687022 ! positive regulation of translation GO:0045727 30 19 0,000 0,061849 0,08681954 ! negative regulation of defense response GO:0031348 25 19 0,000 0,061849 0,08676892 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,061849 0,08671835 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,061849 0,08666785 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,061849 0,0866174 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,061849 0,08656701 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,061849 0,08651668 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,061849 0,08646641 ! bile acid metabolic process GO:0008206 29 19 0,000 0,061849 0,0864162 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,061849 0,08636604 ! cerebral cortex development GO:0021987 36 19 0,000 0,061849 0,08631595 ! pigmentation during development GO:0048066 41 19 0,000 0,061849 0,08626591 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,061849 0,08621593 GO:0030968|endoplasmic reticulum unfolded protein response, ! heme metabolic process GO:0042168 36 19 0,000 0,061849 0,086166 ! actin filament bundle formation GO:0051017 42 19 0,000 0,061849 0,08611614 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,061849 0,08606633 ! plasma membrane fusion GO:0045026 28 19 0,000 0,061849 0,08601658 ! peptide cross-linking GO:0018149 37 19 0,000 0,061849 0,08596689 ! protein export from nucleus GO:0006611 36 19 0,000 0,061849 0,08591726 ! heart process GO:0003015 30 19 0,000 0,061849 0,08586768 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,061849 0,08581816 GO:0006692|prostanoid metabolic process, ! visual learning GO:0008542 36 19 0,000 0,061849 0,0857687 ! cellular pigmentation GO:0033059 36 19 0,000 0,061849 0,08571929 ! G1 phase GO:0051318 40 19 0,000 0,061849 0,08566994 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,061849 0,08562065 ! cell-cell junction organization GO:0045216 35 19 0,000 0,061849 0,08557141 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,061849 0,08552224 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,061849 0,08547311 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,061849 0,08542405 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,061849 0,08537504 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,061849 0,08532608 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,061849 0,08527719 ! cilium assembly GO:0042384 37 19 0,000 0,061849 0,08522835 ! peptide hormone secretion GO:0030072 31 19 0,000 0,061849 0,08517956 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,06499716 0,08946405 ! positive regulation of ossification GO:0045778 47 20 0,000 0,06499716 0,0894129 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,06499716 0,0893618 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,06499716 0,08931077 ! cAMP metabolic process GO:0046058 36 20 0,000 0,06499716 0,08925979 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,06499716 0,08920888 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,06499716 0,08915801 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,06499716 0,08910721 ! response to alkaloid GO:0043279 38 20 0,000 0,06499716 0,08905647 ! retinoid metabolic process GO:0001523 32 20 0,000 0,06499716 0,08900578 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,06499716 0,08895515 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,06499716 0,08890458 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,06499716 0,08885407 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,06499716 0,08880361 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 0,000 0,06499716 0,08875321 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,06499716 0,08870287 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,06499716 0,08865258 ! body fluid secretion GO:0007589 31 20 0,000 0,06499716 0,08860236 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,06499716 0,08855218 ! peptide secretion GO:0002790 35 20 0,000 0,06499716 0,08850207 ! stem cell differentiation GO:0048863 53 20 0,000 0,06499716 0,08845201 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,06499716 0,08840201 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,06499716 0,08835207 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,06499716 0,08830218 ! sensory perception of pain GO:0019233 30 20 0,000 0,06499716 0,08825235 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,06499716 0,08820257 ! diencephalon development GO:0021536 34 20 0,000 0,06499716 0,08815285 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,06499716 0,08810319 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,06499716 0,08805358 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,06499716 0,08800403 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,06499716 0,08795453 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,06499716 0,08790509 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,06499716 0,08785571 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,06499716 0,08780638 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,06499716 0,0877571 ! regulation of glucose import GO:0046324 29 20 0,000 0,06499716 0,08770788 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,06499716 0,08765872 ! actin filament-based movement GO:0030048 43 20 0,000 0,06499716 0,08760961 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,06499716 0,08756056 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,06499716 0,08751156 ! negative regulation of translation GO:0017148 29 20 0,000 0,06499716 0,08746262 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,06499716 0,08741373 ! regulation of cell killing GO:0031341 42 21 0,000 0,06813485 0,09158238 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,06813485 0,09153124 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,06813485 0,09148017 ! hormone secretion GO:0046879 38 21 0,000 0,06813485 0,09142915 ! glycerol metabolic process GO:0006071 34 21 0,000 0,06813485 0,09137818 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,06813485 0,09132728 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,06813485 0,09127642 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,06813485 0,09122563 ! axis specification GO:0009798 38 21 0,000 0,06813485 0,09117489 ! ovarian follicle development GO:0001541 35 21 0,000 0,06813485 0,09112421 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,06813485 0,09107359 ! smooth muscle contraction GO:0006939 46 21 0,000 0,06813485 0,09102302 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,06813485 0,09097251 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,06813485 0,09092205 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,06813485 0,09087165 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,06813485 0,09082131 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,06813485 0,09077102 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,06813485 0,09072079 ! cytolysis GO:0019835 24 21 0,000 0,06813485 0,09067061 ! vasodilation GO:0042311 39 21 0,000 0,06813485 0,09062049 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,06813485 0,09057042 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,06813485 0,09052041 ! DNA modification GO:0006304 34 21 0,000 0,06813485 0,09047045 ! collagen fibril organization GO:0030199 59 21 0,000 0,06813485 0,09042055 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,06813485 0,0903707 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,06813485 0,09032091 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,06813485 0,09027118 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,06813485 0,0902215 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,06813485 0,09017187 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,06813485 0,0901223 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,06813485 0,09007278 ! collagen catabolic process GO:0030574 28 21 0,000 0,06813485 0,09002332 ! sperm-egg recognition GO:0035036 21 21 0,000 0,06813485 0,08997391 ! gut development GO:0048565 39 21 0,000 0,06813485 0,08992455 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,07126213 0,09400037 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,07126213 0,09394886 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,07126213 0,09389741 GO:0034105|positive regulation of tissue remodeling, ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,07126213 0,09384602 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,07126213 0,09379468 ! regeneration GO:0031099 41 22 0,000 0,07126213 0,0937434 ! keratinization GO:0031424 28 22 0,000 0,07126213 0,09369217 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,07126213 0,093641 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,07126213 0,09358989 ! sensory perception of taste GO:0050909 28 22 0,000 0,07126213 0,09353883 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,07126213 0,09348783 ! vacuolar transport GO:0007034 36 22 0,000 0,07126213 0,09343688 ! lysosome organization GO:0007040 41 22 0,000 0,07126213 0,09338599 ! central nervous system neuron development GO:0021954 46 22 0,000 0,07126213 0,09333515 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,07126213 0,09328437 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,07126213 0,09323365 ! fucose metabolic process GO:0006004 39 22 0,000 0,07126213 0,09318298 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,07126213 0,09313236 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,07126213 0,0930818 ! ureteric bud development GO:0001657 43 22 0,000 0,07126213 0,09303129 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,07126213 0,09298084 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,07126213 0,09293045 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,07126213 0,09288011 ! sarcomere organization GO:0045214 30 22 0,000 0,07126213 0,09282982 ! positive regulation of B cell activation GO:0050871 38 22 0,000 0,07126213 0,09277959 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,07126213 0,09272941 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,07126213 0,09267928 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,07126213 0,09262921 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,07126213 0,0925792 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,07437901 0,0965763 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,07437901 0,09652421 ! gluconeogenesis GO:0006094 33 23 0,000 0,07437901 0,09647218 ! viral genome replication GO:0019079 41 23 0,000 0,07437901 0,0964202 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,07437901 0,09636828 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,07437901 0,09631641 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,07437901 0,0962646 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,07437901 0,09621284 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,07437901 0,09616114 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,07437901 0,0961095 ! visual behavior GO:0007632 42 23 0,000 0,07437901 0,09605791 ! regulation of cell-matrix adhesion GO:0001952 78 23 0,000 0,07437901 0,09600638 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 48 23 0,000 0,07437901 0,0959549 ! response to ethanol GO:0045471 46 23 0,000 0,07437901 0,09590348 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,07437901 0,09585211 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,07437901 0,0958008 ! peroxisome organization GO:0007031 37 23 0,000 0,07437901 0,09574954 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,07437901 0,09569834 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,07437901 0,09564719 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,07437901 0,0955961 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,07437901 0,09554506 GO:0051693|actin filament capping, ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,07437901 0,09549407 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,07437901 0,09544314 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,07437901 0,09539227 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,07437901 0,09534144 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,07437901 0,09529068 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,07437901 0,09523996 ! fatty acid transport GO:0015908 44 23 0,000 0,07437901 0,0951893 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,07437901 0,0951387 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,07437901 0,09508815 ! hormone transport GO:0009914 40 23 0,000 0,07437901 0,09503765 ! cell-cell recognition GO:0009988 25 23 0,000 0,07437901 0,0949872 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,07437901 0,09493681 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,07437901 0,09488647 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,07437901 0,09483619 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,07437901 0,09478596 ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,07748553 0,09869253 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,07748553 0,09864031 GO:0016444|somatic cell DNA recombination, ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,07748553 0,09858815 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,07748553 0,09853604 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,07748553 0,09848399 ! vesicle docking GO:0048278 47 24 0,000 0,07748553 0,09843199 ! spinal cord development GO:0021510 47 24 0,000 0,07748553 0,09838005 ! vacuole organization GO:0007033 43 24 0,000 0,07748553 0,09832816 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,07748553 0,09827632 ! digestive system process GO:0022600 39 24 0,000 0,07748553 0,09822454 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,07748553 0,09817282 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,07748553 0,09812115 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,07748553 0,09806953 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,07748553 0,09801797 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,07748553 0,09796647 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 47 24 0,000 0,07748553 0,09791501 ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,07748553 0,09786361 ! membrane depolarization GO:0051899 39 24 0,000 0,07748553 0,09781227 ! pallium development GO:0021543 49 24 0,000 0,07748553 0,09776098 ! pentose metabolic process GO:0019321 35 24 0,000 0,07748553 0,09770974 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,07748553 0,09765856 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,07748553 0,09760743 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,07748553 0,09755635 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,07748553 0,09750533 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,07748553 0,09745436 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,07748553 0,09740344 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,07748553 0,09735258 ! regulation of amine transport GO:0051952 40 24 0,000 0,07748553 0,09730177 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 0,000 0,08058173 0,10113701 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,08058173 0,10108428 ! phototransduction GO:0007602 33 25 0,000 0,08058173 0,1010316 ! sperm motility GO:0030317 31 25 0,000 0,08058173 0,10097898 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,08058173 0,10092642 ! chromosome condensation GO:0030261 45 25 0,000 0,08058173 0,1008739 ! response to starvation GO:0042594 42 25 0,000 0,08058173 0,10082145 ! osteoblast differentiation GO:0001649 60 25 0,000 0,08058173 0,10076905 ! neural crest cell development GO:0014032 54 25 0,000 0,08058173 0,1007167 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,08058173 0,10066441 ! negative regulation of cell development GO:0010721 73 25 0,000 0,08058173 0,10061217 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,08058173 0,10055998 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,08058173 0,10050785 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,08058173 0,10045577 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,08058173 0,10040375 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 0,000 0,08058173 0,10035178 ! immunoglobulin production GO:0002377 55 25 0,000 0,08058173 0,10029987 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,08058173 0,10024801 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,08058173 0,1001962 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,08058173 0,10014444 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,08058173 0,10009274 ! telomere organization GO:0032200 43 25 0,000 0,08058173 0,1000411 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,08058173 0,0999895 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,08058173 0,09993796 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,08366764 0,10371167 ! embryonic pattern specification GO:0009880 44 26 0,000 0,08366764 0,10365826 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,08366764 0,10360491 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,08366764 0,10355162 ! initiation of viral infection GO:0019059 57 26 0,000 0,08366764 0,10349838 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,08366764 0,10344519 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,08366764 0,10339206 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,08366764 0,10333899 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,08366764 0,10328597 ! molting cycle process GO:0022404 50 26 0,000 0,08366764 0,103233 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,08366764 0,10318009 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,08366764 0,10312723 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,08366764 0,10307442 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 0,000 0,08366764 0,10302167 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,08366764 0,10296898 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,08366764 0,10291633 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,08366764 0,10286374 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,08366764 0,10281121 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,08366764 0,10275873 ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,08366764 0,1027063 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,08366764 0,10265393 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,08366764 0,1026016 ! leukocyte proliferation GO:0070661 52 26 0,000 0,08366764 0,10254934 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,08366764 0,10249712 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,08366764 0,10244496 ! neuron fate commitment GO:0048663 48 27 0,000 0,0867433 0,10615685 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,0867433 0,10610289 ! iron ion transport GO:0006826 59 27 0,000 0,0867433 0,10604897 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,0867433 0,10599511 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,0867433 0,10594131 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,0867433 0,10588756 ! fat cell differentiation GO:0045444 50 27 0,000 0,0867433 0,10583386 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,0867433 0,10578022 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,0867433 0,10572663 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,0867433 0,1056731 ! autophagy GO:0006914 41 27 0,000 0,0867433 0,10561962 ! male gonad development GO:0008584 44 27 0,000 0,0867433 0,1055662 ! response to toxin GO:0009636 47 27 0,000 0,0867433 0,10551283 ! primary neural tube formation GO:0014020 51 27 0,000 0,0867433 0,10545951 ! base-excision repair GO:0006284 41 27 0,000 0,0867433 0,10540625 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,0867433 0,10535304 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,0867433 0,10529989 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,0867433 0,10524679 ! glutathione metabolic process GO:0006749 39 27 0,000 0,0867433 0,10519374 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,0867433 0,10514074 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,0867433 0,1050878 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,0867433 0,10503491 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,08980873 0,10869206 ! circadian rhythm GO:0007623 50 28 0,000 0,08980873 0,10863741 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,08980873 0,10858282 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,08980873 0,10852828 ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,08980873 0,1084738 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,08980873 0,10841937 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,08980873 0,108365 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,08980873 0,10831068 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,08980873 0,10825642 ! synaptogenesis GO:0007416 42 28 0,000 0,08980873 0,10820221 ! lipid oxidation GO:0034440 43 28 0,000 0,08980873 0,10814805 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,08980873 0,10809395 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,08980873 0,10803991 ! translational initiation GO:0006413 65 29 0,000 0,09286398 0,11165954 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,09286398 0,11160376 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,09286398 0,11154805 ! regulation of pH GO:0006885 43 29 0,000 0,09286398 0,11149238 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,09286398 0,11143678 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,09286398 0,11138122 ! catechol metabolic process GO:0009712 54 29 0,000 0,09286398 0,11132573 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,09286398 0,11127029 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,09286398 0,1112149 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,09286398 0,11115957 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,09286398 0,11110429 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,09286398 0,11104907 ! cell fate determination GO:0001709 60 29 0,000 0,09286398 0,11099391 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,09286398 0,1109388 ! detection of light stimulus GO:0009583 38 29 0,000 0,09286398 0,11088374 ! cellular response to extracellular stimulus GO:0031668 48 29 0,000 0,09286398 0,11082874 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,09286398 0,11077379 ! phenol metabolic process GO:0018958 55 30 0,000 0,09590907 0,11434947 ! zinc ion transport GO:0006829 45 30 0,000 0,09590907 0,11429283 ! membrane docking GO:0022406 61 30 0,000 0,09590907 0,11423625 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,09590907 0,11417973 ! cell junction assembly GO:0034329 78 30 0,000 0,09590907 0,11412326 ! regulation of innate immune response GO:0045088 51 30 0,000 0,09590907 0,11406684 ! acute-phase response GO:0006953 49 30 0,000 0,09590907 0,11401049 ! myofibril assembly GO:0030239 47 30 0,000 0,09590907 0,11395419 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,09590907 0,11389794 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,09590907 0,11384175 ! phospholipid transport GO:0015914 51 30 0,000 0,09590907 0,11378561 ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,09590907 0,11372954 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,09590907 0,11367351 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,09590907 0,11361754 ! eye morphogenesis GO:0048592 60 30 0,000 0,09590907 0,11356163 ! regulation of B cell activation GO:0050864 50 30 0,000 0,09590907 0,11350577 ! response to heat GO:0009408 50 30 0,000 0,09590907 0,11344996 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,09894404 0,11698249 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,09894404 0,11692503 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,09894404 0,11686763 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,09894404 0,11681029 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,09894404 0,116753 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,09894404 0,11669577 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,09894404 0,11663859 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,09894404 0,11658147 ! ovulation cycle process GO:0022602 49 31 0,000 0,09894404 0,11652441 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,09894404 0,1164674 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,09894404 0,11641045 ! peptide transport GO:0015833 55 31 0,000 0,09894404 0,11635355 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,09894404 0,11629671 ! iron ion homeostasis GO:0055072 54 31 0,000 0,09894404 0,11623993 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,09894404 0,1161832 ! mesoderm formation GO:0001707 69 31 0,000 0,09894404 0,11612652 ! natural killer cell activation GO:0030101 45 31 0,000 0,09894404 0,1160699 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,09894404 0,11601334 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,09894404 0,11595683 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,09894404 0,11590037 ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,09894404 0,11584397 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,10196893 0,11932745 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,10196893 0,11926944 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,10196893 0,11921149 ! cholesterol transport GO:0030301 56 32 0,000 0,10196893 0,11915359 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,10196893 0,11909575 ! spliceosome assembly GO:0000245 67 32 0,000 0,10196893 0,11903796 ! spindle organization GO:0007051 46 32 0,000 0,10196893 0,11898023 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,10196893 0,11892256 ! metanephros development GO:0001656 74 32 0,000 0,10196893 0,11886494 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,10196893 0,11880738 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,10196893 0,11874987 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,10196893 0,11869242 ! muscle cell development GO:0055001 49 32 0,000 0,10196893 0,11863503 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,10196893 0,11857769 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,10196893 0,11852041 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,10196893 0,11846318 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,10196893 0,118406 ! ovulation cycle GO:0042698 51 32 0,000 0,10196893 0,11834888 ! BMP signaling pathway GO:0030509 64 32 0,000 0,10196893 0,11829182 ! hindbrain development GO:0030902 61 32 0,000 0,10196893 0,11823481 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,10196893 0,11817786 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,10196893 0,11812096 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,10498376 0,12155482 ! post-embryonic development GO:0009791 69 33 0,000 0,10498376 0,12149635 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,10498376 0,12143794 ! protein targeting to membrane GO:0006612 68 33 0,000 0,10498376 0,12137959 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,10498376 0,12132129 ! ceramide metabolic process GO:0006672 64 33 0,000 0,10498376 0,12126304 ! formation of primary germ layer GO:0001704 72 33 0,000 0,10498376 0,12120485 ! sterol transport GO:0015918 57 33 0,000 0,10498376 0,12114672 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,10498376 0,12108865 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,10498376 0,12103063 ! adult locomotory behavior GO:0008344 59 33 0,000 0,10498376 0,12097266 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,10498376 0,12091475 ! glial cell differentiation GO:0010001 63 34 0,000 0,10798856 0,12431602 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,10798856 0,12425657 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,10798856 0,12419717 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,10798856 0,12413783 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,10798856 0,12407855 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,10798856 0,12401932 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,10798856 0,12396016 ! mismatch repair GO:0006298 46 34 0,000 0,10798856 0,12390104 ! spermatid development GO:0007286 63 34 0,000 0,10798856 0,12384199 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,10798856 0,12378298 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,10798856 0,12372404 ! placenta development GO:0001890 53 34 0,000 0,10798856 0,12366515 ! regulation of muscle development GO:0048634 70 35 0,000 0,11098338 0,12703426 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,11098338 0,12697386 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,11098338 0,12691351 ! odontogenesis GO:0042476 66 35 0,000 0,11098338 0,12685322 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,11098338 0,12679298 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,11098338 0,12673281 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,11098338 0,12667269 ! cytokine production GO:0001816 59 35 0,000 0,11098338 0,12661262 ! neural tube formation GO:0001841 67 35 0,000 0,11098338 0,12655262 ! vesicle localization GO:0051648 64 35 0,000 0,11098338 0,12649267 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,11396825 0,12983315 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,11396825 0,1297717 ! cell junction organization GO:0034330 86 36 0,000 0,11396825 0,12971031 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,11396825 0,12964899 ! positive regulation of cell development GO:0010720 80 36 0,000 0,11396825 0,12958771 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,11396825 0,1295265 ! regulation of proteolysis GO:0030162 72 36 0,000 0,11396825 0,12946535 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,11396825 0,12940425 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,11396825 0,12934321 ! aerobic respiration GO:0009060 55 36 0,000 0,11396825 0,12928223 ! androgen receptor signaling pathway GO:0030521 74 36 0,000 0,11396825 0,1292213 ! embryonic organ development GO:0048568 57 36 0,000 0,11396825 0,12916044 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,11396825 0,12909963 ! RNA export from nucleus GO:0006405 56 37 0,000 0,11694319 0,13240721 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,11694319 0,13234493 ! meiosis I GO:0007127 65 37 0,000 0,11694319 0,1322827 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,11694319 0,13222054 ! sister chromatid segregation GO:0000819 58 37 0,000 0,11694319 0,13215844 ! actomyosin structure organization GO:0031032 62 37 0,000 0,11694319 0,13209639 ! organic anion transport GO:0015711 68 37 0,000 0,11694319 0,1320344 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,11694319 0,13197247 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,11694319 0,1319106 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,11694319 0,13184879 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,11694319 0,13178703 GO:0015986|ATP synthesis coupled proton transport, ! pigment metabolic process GO:0042440 80 37 0,000 0,11694319 0,13172533 ! spermatid differentiation GO:0048515 66 37 0,000 0,11694319 0,13166369 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,11990824 0,13493883 GO:0006956|complement activation, ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,11990824 0,13487575 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,11990824 0,13481272 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,11990824 0,13474976 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,11990824 0,13468685 ! nucleus organization GO:0006997 67 38 0,000 0,11990824 0,134624 ! lipid homeostasis GO:0055088 67 38 0,000 0,11990824 0,13456121 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,11990824 0,13449847 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,11990824 0,1344358 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,11990824 0,13437318 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,11990824 0,13431063 ! positive regulation of leukocyte proliferation GO:0070665 62 38 0,000 0,11990824 0,13424813 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,11990824 0,13418569 ! mRNA catabolic process GO:0006402 71 39 0,000 0,12286343 0,13742883 ! learning GO:0007612 77 39 0,000 0,12286343 0,13736497 ! ear morphogenesis GO:0042471 60 39 0,000 0,12286343 0,13730117 ! organic ether metabolic process GO:0018904 55 39 0,000 0,12286343 0,13723743 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,12286343 0,13717375 ! segmentation GO:0035282 67 39 0,000 0,12286343 0,13711012 ! ion transmembrane transport GO:0034220 66 39 0,000 0,12286343 0,13704656 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,12286343 0,13698305 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,12286343 0,1369196 ! RNA modification GO:0009451 57 39 0,000 0,12286343 0,13685621 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,12286343 0,13679288 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,1258088 0,14000739 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,1258088 0,13994266 ! feeding behavior GO:0007631 59 40 0,000 0,1258088 0,13987799 ! mesenchymal cell development GO:0014031 87 40 0,000 0,1258088 0,13981338 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,1258088 0,13974884 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,12874438 0,14294369 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,12874438 0,14287776 ! gliogenesis GO:0042063 88 41 0,000 0,12874438 0,14281188 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,12874438 0,14274607 ! T cell differentiation GO:0030217 81 41 0,000 0,12874438 0,14268032 ! polyol metabolic process GO:0019751 66 41 0,000 0,12874438 0,14261463 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,12874438 0,142549 ! response to reactive oxygen species GO:0000302 67 42 0,000 0,13167019 0,14572147 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,13167019 0,14565448 ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,13167019 0,14558754 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,13167019 0,14552066 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,13167019 0,14545385 ! neuron migration GO:0001764 79 42 0,000 0,13167019 0,1453871 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,13167019 0,14532041 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,13458628 0,1484707 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,13458628 0,14840265 ! neural tube development GO:0021915 77 43 0,000 0,13458628 0,14833467 ! striated muscle contraction GO:0006941 77 43 0,000 0,13458628 0,14826675 ! phagocytosis GO:0006909 90 43 0,000 0,13458628 0,1481989 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,13458628 0,1481311 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,13749267 0,1512608 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,13749267 0,15119167 ! male sex differentiation GO:0046661 76 44 0,000 0,13749267 0,1511226 ! B cell differentiation GO:0030183 107 44 0,000 0,13749267 0,15105359 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,13749267 0,15098465 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,1403894 0,1540953 ! glycolysis GO:0006096 65 45 0,000 0,1403894 0,15402503 ! leukocyte migration GO:0050900 68 45 0,000 0,1403894 0,15395483 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,1403894 0,15388469 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,1403894 0,15381461 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,1403894 0,1537446 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,1403894 0,15367465 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,1403894 0,15360477 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,1403894 0,15353495 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,14327649 0,15662119 ! pigmentation GO:0043473 100 46 0,000 0,14327649 0,15655006 ! response to calcium ion GO:0051592 81 47 0,000 0,14615398 0,15962164 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,14615398 0,15954922 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,14615398 0,15947686 ! JNK cascade GO:0007254 91 47 0,000 0,14615398 0,15940457 ! protein homooligomerization GO:0051260 76 47 0,000 0,14615398 0,15933234 ! mitochondrial transport GO:0006839 82 48 0,000 0,14902191 0,16238528 ! Notch signaling pathway GO:0007219 96 48 0,000 0,14902191 0,16231177 ! cellular component disassembly GO:0022411 86 48 0,000 0,14902191 0,16223833 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,14902191 0,16216495 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,14902191 0,16209164 ! activation of caspase activity GO:0006919 84 48 0,000 0,14902191 0,16201839 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,14902191 0,16194521 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,15188029 0,16497697 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,15188029 0,16490252 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,15188029 0,16482814 ! regulation of ion transport GO:0043269 77 49 0,000 0,15188029 0,16475382 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,15188029 0,16467958 ! peptide metabolic process GO:0006518 76 49 0,000 0,15188029 0,1646054 ! response to temperature stimulus GO:0009266 76 49 0,000 0,15188029 0,16453128 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,15188029 0,16445724 ! endocrine system development GO:0035270 104 49 0,000 0,15188029 0,16438326 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,15188029 0,16430934 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,15188029 0,1642355 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,15188029 0,16416172 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,15472917 0,16716586 ! neuromuscular process GO:0050905 99 50 0,000 0,15472917 0,16709084 ! regulation of ossification GO:0030278 117 50 0,000 0,15472917 0,16701587 ! inner ear development GO:0048839 79 50 0,000 0,15472917 0,16694098 ! viral infectious cycle GO:0019058 99 51 0,000 0,15756857 0,16992828 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,15756857 0,16985214 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,15756857 0,16977608 ! excretion GO:0007588 83 51 0,000 0,15756857 0,16970008 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,15756857 0,16962416 ! chromatin remodeling GO:0006338 109 51 0,000 0,15756857 0,16954829 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,15756857 0,1694725 ! vesicle organization GO:0016050 107 51 0,000 0,15756857 0,16939678 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,15756857 0,16932112 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,16039853 0,17228521 ! membrane fusion GO:0006944 110 52 0,000 0,16039853 0,17220833 ! amino acid activation GO:0043038 92 52 0,000 0,16039853 0,17213152 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,16039853 0,17205478 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,16321908 0,17500228 ! RNA catabolic process GO:0006401 93 53 0,000 0,16321908 0,17492432 ! regulation of translational initiation GO:0006446 82 53 0,000 0,16321908 0,17484644 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,16321908 0,17476863 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,16321908 0,17469088 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,16321908 0,17461321 ! regulation of neuron apoptosis GO:0043523 100 53 0,000 0,16321908 0,1745356 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,16321908 0,17445807 ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,16603025 0,177384 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,16603025 0,17730527 ! cell recognition GO:0008037 85 54 0,000 0,16603025 0,17722661 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,16603025 0,17714801 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,16603025 0,17706949 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,16603025 0,17699104 ! chloride transport GO:0006821 90 55 0,000 0,16883206 0,17989811 ! positive regulation of caspase activity GO:0043280 95 55 0,000 0,16883206 0,17981848 GO:0010952|positive regulation of peptidase activity, ! glucose catabolic process GO:0006007 82 55 0,000 0,16883206 0,17973891 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,16883206 0,17965941 ! gastrulation GO:0007369 112 55 0,000 0,16883206 0,17957999 ! RNA elongation GO:0006354 79 55 0,000 0,16883206 0,17950063 ! nuclear export GO:0051168 97 55 0,000 0,16883206 0,17942135 ! regulation of actin filament length GO:0030832 105 56 0,000 0,17162455 0,18230847 ! sensory perception of smell GO:0007608 80 56 0,000 0,17162455 0,18222801 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,17162455 0,18214763 ! proton transport GO:0015992 94 56 0,000 0,17162455 0,18206732 ! hydrogen transport GO:0006818 97 58 0,000 0,1771817 0,18787976 ! regulation of endocytosis GO:0030100 91 58 0,000 0,1771817 0,187797 ! adult behavior GO:0030534 99 58 0,000 0,1771817 0,1877143 ! positive regulation of secretion GO:0051047 95 59 0,000 0,17994642 0,19055946 ! regulation of cellular component size GO:0032535 109 59 0,000 0,17994642 0,19047562 ! skeletal system morphogenesis GO:0048705 105 59 0,000 0,17994642 0,19039186 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,17994642 0,19030817 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,17994642 0,19022456 ! DNA catabolic process GO:0006308 86 59 0,000 0,17994642 0,19014102 ! establishment of organelle localization GO:0051656 109 59 0,000 0,17994642 0,19005755 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,18270194 0,19288323 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,18270194 0,19279863 ! regulation of heart contraction GO:0008016 110 60 0,000 0,18270194 0,1927141 ! camera-type eye development GO:0043010 116 60 0,000 0,18270194 0,19262966 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,18270194 0,19254528 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,18544829 0,19535403 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,18544829 0,19526853 ! mesoderm development GO:0007498 119 61 0,000 0,18544829 0,19518311 ! tRNA processing GO:0008033 89 61 0,000 0,18544829 0,19509777 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,18544829 0,1950125 ! ear development GO:0043583 103 62 0,000 0,18818551 0,19780443 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,18818551 0,19771805 ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,19091362 0,2004968 ! detection of external stimulus GO:0009581 91 63 0,000 0,19091362 0,20040932 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,19091362 0,20032192 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,19363265 0,20308638 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,19363265 0,20299789 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,19363265 0,20290947 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,19634263 0,20565971 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,19634263 0,20557022 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,19634263 0,2054808 GO:0035113|embryonic appendage morphogenesis, ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,19904359 0,20821691 ! extracellular matrix organization GO:0030198 133 66 0,000 0,19904359 0,20812642 ! secondary metabolic process GO:0019748 116 66 0,000 0,19904359 0,20803601 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,20173557 0,21075805 ! negative regulation of cell growth GO:0030308 132 67 0,000 0,20173557 0,21066657 ! chromosome segregation GO:0007059 113 67 0,000 0,20173557 0,21057518 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,20173557 0,21048386 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,20173557 0,21039262 ! hexose catabolic process GO:0019320 104 67 0,000 0,20173557 0,21030147 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,20173557 0,21021039 ! activation of immune response GO:0002253 105 67 0,000 0,20173557 0,21011939 ! amino acid transport GO:0006865 125 68 0,000 0,20441859 0,21282178 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,20441859 0,21272973 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,20441859 0,21263775 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,20441859 0,21254586 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,20441859 0,21245405 ! cell cycle checkpoint GO:0000075 137 69 0,000 0,20709268 0,21514032 ! negative regulation of cell size GO:0045792 134 69 0,000 0,20709268 0,21504747 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,20709268 0,2149547 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,20709268 0,214862 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,20709268 0,21476939 ! antigen processing and presentation GO:0019882 104 69 0,000 0,20709268 0,21467686 ! appendage morphogenesis GO:0035107 135 70 0,000 0,20975787 0,21734601 GO:0035108|limb morphogenesis, ! amine catabolic process GO:0009310 117 71 0,000 0,21241419 0,22000368 ! appendage development GO:0048736 136 71 0,000 0,21241419 0,21990901 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,21241419 0,21981443 ! B cell activation GO:0042113 160 71 0,000 0,21241419 0,21971992 ! regulation of immune effector process GO:0002697 137 71 0,000 0,21241419 0,2196255 ! acute inflammatory response GO:0002526 113 72 0,000 0,21506167 0,22226734 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,21506167 0,22217191 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,21506167 0,22207656 ! learning or memory GO:0007611 147 73 0,000 0,21770034 0,22470485 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,21770034 0,22460849 ! fertilization GO:0009566 90 73 0,000 0,21770034 0,22451222 ! transition metal ion transport GO:0000041 126 74 0,000 0,22033022 0,22712704 ! neurotransmitter transport GO:0006836 123 74 0,000 0,22033022 0,22702977 ! exocytosis GO:0006887 133 74 0,000 0,22033022 0,22693258 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,22033022 0,22683548 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,22033022 0,22673846 ! eye development GO:0001654 143 74 0,000 0,22033022 0,22664152 ! organelle localization GO:0051640 136 74 0,000 0,22033022 0,22654466 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,22295135 0,2291418 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,22295135 0,22904396 ! rhythmic process GO:0048511 128 75 0,000 0,22295135 0,2289462 ! lymphocyte differentiation GO:0030098 167 75 0,000 0,22295135 0,22884853 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,22556376 0,2314313 ! defense response to bacterium GO:0042742 89 76 0,000 0,22556376 0,23133265 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,22556376 0,23123409 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,22556376 0,23113561 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,22816747 0,2337041 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,22816747 0,23360465 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,22816747 0,23350529 ! positive regulation of lymphocyte activation GO:0051251 127 77 0,000 0,22816747 0,23340601 ! negative regulation of organelle organization GO:0010639 161 78 0,000 0,23076251 0,23596031 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,23334892 0,23850361 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 0,000 0,23334892 0,23840233 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,23334892 0,23830114 ! response to metal ion GO:0010038 140 80 0,000 0,23592671 0,24083142 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,23592671 0,24072929 ! protein import into nucleus GO:0006606 158 80 0,000 0,23592671 0,24062724 ! inorganic anion transport GO:0015698 138 80 0,000 0,23592671 0,24052528 ! T cell activation GO:0042110 168 81 0,000 0,23849592 0,24304159 ! digestion GO:0007586 112 81 0,000 0,23849592 0,24293869 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,23849592 0,24283588 ! nuclear import GO:0051170 161 81 0,000 0,23849592 0,24273316 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,23849592 0,24263052 ! response to drug GO:0042493 143 82 0,000 0,24105658 0,24513192 ! negative regulation of growth GO:0045926 155 84 0,000 0,24615234 0,25020809 ! regulation of ligase activity GO:0051340 142 84 0,000 0,24615234 0,25010242 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,24615234 0,24999685 ! response to unfolded protein GO:0006986 131 85 0,000 0,24868751 0,25246504 ! nucleosome assembly GO:0006334 122 85 0,000 0,24868751 0,25235856 ! positive regulation of cell activation GO:0050867 145 85 0,000 0,24868751 0,25225217 GO:0002696|positive regulation of leukocyte activation, ! amine biosynthetic process GO:0009309 138 86 0,000 0,25121423 0,25470773 ! response to inorganic substance GO:0010035 153 86 0,000 0,25121423 0,25460044 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,25121423 0,25449324 ! chromatin assembly GO:0031497 124 86 0,000 0,25121423 0,25438613 ! alcohol catabolic process GO:0046164 130 86 0,000 0,25121423 0,25427911 ! amine transport GO:0015837 155 86 0,000 0,25121423 0,25417218 ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,25373254 0,25661223 ! protein localization in nucleus GO:0034504 176 87 0,000 0,25373254 0,25650441 ! cellular respiration GO:0045333 135 88 0,000 0,25624247 0,25893296 ! regulation of neurological system process GO:0031644 148 88 0,000 0,25624247 0,25882426 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,25624247 0,25871564 ! cellular defense response GO:0006968 114 89 0,000 0,25874403 0,26113177 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,26123727 0,26353747 ! response to protein stimulus GO:0051789 149 91 0,000 0,2637222 0,26593278 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,2637222 0,26582137 ! nucleosome organization GO:0034728 138 92 0,000 0,26619885 0,26820538 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,26619885 0,26809311 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,26866726 0,27046587 GO:0010498|proteasomal protein catabolic process, ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,26866726 0,27035275 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,27112745 0,27271431 ! female pregnancy GO:0007565 164 94 0,000 0,27112745 0,27260035 ! forebrain development GO:0030900 188 95 0,000 0,27357944 0,27495076 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,27357944 0,27483596 ! leukocyte differentiation GO:0002521 202 96 0,000 0,27602326 0,27717528 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,27602326 0,27705964 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,27602326 0,27694411 ! positive regulation of immune response GO:0050778 156 96 0,000 0,27602326 0,27682866 ! detection of stimulus GO:0051606 151 96 0,000 0,27602326 0,27671332 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,27845894 0,27903883 ! hormone metabolic process GO:0042445 157 97 0,000 0,27845894 0,27892266 ! response to virus GO:0009615 160 98 0,000 0,28088651 0,28123718 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,28088651 0,2811202 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,28088651 0,28100331 GO:0016054|organic acid catabolic process, ! Golgi vesicle transport GO:0048193 207 99 0,000 0,283306 0,283306