pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6659-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! sex determination GO:0007530 47 23 5,000 4,021E-09 9,674E-06 ! induction of apoptosis by intracellular signals GO:0008629 93 45 5,000 2,907E-07 3,497E-04 ! ribosomal large subunit biogenesis GO:0042273 13 13 3,000 8,649E-07 6,936E-04 ! response to gamma radiation GO:0010332 28 14 3,000 1,205E-06 7,249E-04 ! DNA damage checkpoint GO:0000077 71 33 4,000 1,536E-06 7,391E-04 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 3,000 1,636E-06 6,559E-04 ! DNA damage response, signal transduction GO:0042770 128 60 5,000 1,658E-06 5,7E-04 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 2,000 2,116E-06 6,364E-04 ! meiotic chromosome segregation GO:0045132 7 5 2,000 2,116E-06 5,657E-04 ! DNA integrity checkpoint GO:0031570 75 36 4,000 2,404E-06 5,785E-04 ! negative regulation of protein kinase activity GO:0006469 130 67 5,000 3,193E-06 6,984E-04 ! negative regulation of kinase activity GO:0033673 131 68 5,000 3,484E-06 6,986E-04 ! neural nucleus development GO:0048857 14 6 2,000 4,214E-06 7,798E-04 ! negative regulation of transferase activity GO:0051348 140 72 5,000 4,876E-06 8,38E-04 ! C21-steroid hormone metabolic process GO:0008207 33 20 3,000 5,671E-06 9,096E-04 ! meiosis GO:0007126 121 74 5,000 5,724E-06 8,608E-04 GO:0051327|M phase of meiotic cell cycle, ! meiotic cell cycle GO:0051321 122 75 5,000 6,191E-06 8,762E-04 ! cell aging GO:0007569 44 21 3,000 6,972E-06 9,32E-04 ! positive regulation of inflammatory response GO:0050729 35 21 3,000 6,972E-06 8,829E-04 ! N-terminal protein amino acid acetylation GO:0006474 13 7 2,000 7,341E-06 8,831E-04 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 2,000 7,341E-06 8,411E-04 ! B cell lineage commitment GO:0002326 21 7 2,000 7,341E-06 8,029E-04 ! T cell lineage commitment GO:0002360 16 7 2,000 7,341E-06 7,679E-04 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 2,000 1,169E-05 1,172E-03 ! negative regulation of phosphorylation GO:0042326 47 24 3,000 1,221E-05 1,175E-03 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 3,000 1,446E-05 1,338E-03 ! response to UV GO:0009411 104 53 4,000 1,685E-05 1,502E-03 ! insulin receptor signaling pathway GO:0008286 64 26 3,000 1,701E-05 1,462E-03 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 3,000 1,701E-05 1,411E-03 GO:0045936|negative regulation of phosphate metabolic process, ! induction of positive chemotaxis GO:0050930 15 9 2,000 1,746E-05 1,401E-03 ! interphase of mitotic cell cycle GO:0051329 209 95 5,000 2,42E-05 1,878E-03 ! regulation of smooth muscle cell migration GO:0014910 27 10 2,000 2,484E-05 1,867E-03 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 2,000 2,484E-05 1,811E-03 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 2,000 2,484E-05 1,758E-03 ! oocyte development GO:0048599 17 10 2,000 2,484E-05 1,707E-03 ! interphase GO:0051325 213 98 5,000 2,887E-05 1,93E-03 ! cell cycle arrest GO:0007050 213 100 5,000 3,238E-05 2,105E-03 ! response to peptide hormone stimulus GO:0043434 122 61 4,000 3,36E-05 2,128E-03 ! peptide or protein amino-terminal blocking GO:0018409 21 11 2,000 3,4E-05 2,098E-03 ! chondrocyte differentiation GO:0002062 24 11 2,000 3,4E-05 2,045E-03 ! oocyte differentiation GO:0009994 18 11 2,000 3,4E-05 1,995E-03 ! negative regulation of glucose import GO:0046325 17 11 2,000 3,4E-05 1,948E-03 GO:0010829|negative regulation of glucose transport, ! response to ionizing radiation GO:0010212 65 32 3,000 3,978E-05 2,226E-03 ! hindbrain development GO:0030902 61 32 3,000 3,978E-05 2,175E-03 ! regulation of positive chemotaxis GO:0050926 19 12 2,000 4,513E-05 2,413E-03 GO:0050927|positive regulation of positive chemotaxis, ! focal adhesion formation GO:0048041 35 12 2,000 4,513E-05 2,361E-03 ! histone acetylation GO:0016573 26 12 2,000 4,513E-05 2,31E-03 ! peptidyl-lysine modification GO:0018205 21 12 2,000 4,513E-05 2,262E-03 ! spleen development GO:0048536 22 12 2,000 4,513E-05 2,216E-03 ! negative regulation of cell growth GO:0030308 132 67 4,000 5,298E-05 2,55E-03 ! response to X-ray GO:0010165 25 13 2,000 5,841E-05 2,756E-03 ! cell cycle checkpoint GO:0000075 137 69 4,000 6,106E-05 2,825E-03 ! negative regulation of cell size GO:0045792 134 69 4,000 6,106E-05 2,772E-03 ! hormone biosynthetic process GO:0042446 57 36 3,000 6,396E-05 2,85E-03 ! meiosis I GO:0007127 65 37 3,000 7,137E-05 3,122E-03 ! cellular response to insulin stimulus GO:0032869 82 37 3,000 7,137E-05 3,067E-03 ! N-terminal protein amino acid modification GO:0031365 27 14 2,000 7,401E-05 3,124E-03 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 2,000 7,401E-05 3,07E-03 ! release of cytochrome c from mitochondria GO:0001836 30 14 2,000 7,401E-05 3,018E-03 ! regulation of the force of heart contraction GO:0002026 26 15 2,000 9,211E-05 3,694E-03 ! T cell differentiation GO:0030217 81 41 3,000 1,074E-04 4,236E-03 ! embryonic forelimb morphogenesis GO:0035115 28 16 2,000 1,129E-04 4,38E-03 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 2,000 1,129E-04 4,31E-03 ! positive regulation of response to external stimulus GO:0032103 77 43 3,000 1,297E-04 4,875E-03 ! signal complex assembly GO:0007172 41 17 2,000 1,364E-04 5,051E-03 ! neutrophil chemotaxis GO:0030593 27 17 2,000 1,364E-04 4,974E-03 ! glycolysis GO:0006096 65 45 3,000 1,551E-04 5,57E-03 ! negative regulation of transport GO:0051051 153 84 4,000 1,56E-04 5,519E-03 ! negative regulation of growth GO:0045926 155 84 4,000 1,56E-04 5,439E-03 ! cell-substrate junction assembly GO:0007044 54 18 2,000 1,63E-04 5,603E-03 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 3,000 1,691E-04 5,729E-03 ! response to insulin stimulus GO:0032868 95 46 3,000 1,691E-04 5,65E-03 ! alcohol catabolic process GO:0046164 130 86 4,000 1,743E-04 5,744E-03 ! positive regulation of defense response GO:0031349 76 47 3,000 1,839E-04 5,98E-03 ! forelimb morphogenesis GO:0035136 32 19 2,000 1,927E-04 6,182E-03 ! regulation of inflammatory response GO:0050727 75 48 3,000 1,997E-04 6,323E-03 ! protein amino acid acetylation GO:0006473 39 20 2,000 2,257E-04 7,053E-03 ! apoptotic mitochondrial changes GO:0008637 41 20 2,000 2,257E-04 6,963E-03 ! regulation of glucose import GO:0046324 29 20 2,000 2,257E-04 6,875E-03 GO:0010827|regulation of glucose transport, ! chromatin remodeling GO:0006338 109 51 3,000 2,529E-04 7,607E-03 ! reciprocal meiotic recombination GO:0007131 39 21 2,000 2,622E-04 7,788E-03 ! inactivation of MAPK activity GO:0000188 39 21 2,000 2,622E-04 7,693E-03 ! oogenesis GO:0048477 36 21 2,000 2,622E-04 7,6E-03 ! positive regulation of locomotion GO:0040017 39 21 2,000 2,622E-04 7,51E-03 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! regulation of chemotaxis GO:0050920 40 22 2,000 3,022E-04 8,555E-03 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 2,000 3,022E-04 8,456E-03 ! response to glucocorticoid stimulus GO:0051384 38 22 2,000 3,022E-04 8,359E-03 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 2,000 3,022E-04 8,264E-03 ! glucose catabolic process GO:0006007 82 55 3,000 3,388E-04 9,159E-03 ! aging GO:0007568 103 55 3,000 3,388E-04 9,057E-03 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 1,000 3,55E-04 9,385E-03 ! positive regulation of glycolysis GO:0045821 14 5 1,000 3,55E-04 9,283E-03 ! microvillus organization GO:0032528 7 5 1,000 3,55E-04 9,183E-03 GO:0030033|microvillus assembly, ! polyol catabolic process GO:0046174 7 5 1,000 3,55E-04 9,085E-03 GO:0019405|alditol catabolic process, ! morphogenesis of an epithelial sheet GO:0002011 11 5 1,000 3,55E-04 8,99E-03 ! peptidyl-threonine phosphorylation GO:0018107 20 5 1,000 3,55E-04 8,896E-03 ! early endosome to late endosome transport GO:0045022 12 5 1,000 3,55E-04 8,804E-03 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 1,000 3,55E-04 8,714E-03 ! homeostasis of number of cells within a tissue GO:0048873 12 5 1,000 3,55E-04 8,626E-03 ! neural tube patterning GO:0021532 7 5 1,000 3,55E-04 8,54E-03 ! B cell homeostasis GO:0001782 13 5 1,000 3,55E-04 8,456E-03 ! inner cell mass cell proliferation GO:0001833 5 5 1,000 3,55E-04 8,373E-03 ! regulation of mitochondrial depolarization GO:0051900 13 5 1,000 3,55E-04 8,291E-03 ! hemopoietic progenitor cell differentiation GO:0002244 14 5 1,000 3,55E-04 8,212E-03 ! regulation of DNA replication GO:0006275 101 56 3,000 3,632E-04 8,322E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 3,000 3,888E-04 8,824E-03 ! response to corticosteroid stimulus GO:0031960 41 24 2,000 3,937E-04 8,854E-03 ! regulation of behavior GO:0050795 43 24 2,000 3,937E-04 8,772E-03 ! protein tetramerization GO:0051262 52 24 2,000 3,937E-04 8,691E-03 ! integrin-mediated signaling pathway GO:0007229 135 59 3,000 4,438E-04 9,706E-03 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 2,000 4,455E-04 9,656E-03 ! negative regulation of DNA replication GO:0008156 42 25 2,000 4,455E-04 9,569E-03 ! male meiosis GO:0007140 7 6 1,000 5,303E-04 0,01129167 ! malate metabolic process GO:0006108 11 6 1,000 5,303E-04 0,01119262 ! activation of MAPKKK activity GO:0000185 12 6 1,000 5,303E-04 0,01109529 ! male sex determination GO:0030238 15 6 1,000 5,303E-04 0,01099964 ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 1,000 5,303E-04 0,01090563 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! establishment of spindle localization GO:0051293 12 6 1,000 5,303E-04 0,01081321 GO:0051653|spindle localization, ! response to UV-C GO:0010225 11 6 1,000 5,303E-04 0,01072234 ! regulation of myeloid cell apoptosis GO:0033032 13 6 1,000 5,303E-04 0,01063299 ! negative regulation of neuroblast proliferation GO:0007406 21 6 1,000 5,303E-04 0,01054511 ! cytoplasmic microtubule organization GO:0031122 14 6 1,000 5,303E-04 0,01045867 ! gonad development GO:0008406 98 62 3,000 5,363E-04 0,01049133 ! regulation of fibroblast proliferation GO:0048145 52 27 2,000 5,615E-04 0,01089552 ! protein amino acid acylation GO:0043543 55 27 2,000 5,615E-04 0,01080835 ! mitochondrial membrane organization GO:0007006 57 27 2,000 5,615E-04 0,01072257 ! male gonad development GO:0008584 44 27 2,000 5,615E-04 0,01063814 ! negative regulation of protein modification process GO:0031400 60 28 2,000 6,261E-04 0,01176957 ! germ cell development GO:0007281 118 65 3,000 6,419E-04 0,01197208 ! actin filament organization GO:0007015 148 66 3,000 6,801E-04 0,01258761 ! response to organic cyclic substance GO:0014070 55 29 2,000 6,953E-04 0,0127705 ! cellular response to extracellular stimulus GO:0031668 48 29 2,000 6,953E-04 0,01267375 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 2,000 6,953E-04 0,01257846 ! tissue homeostasis GO:0001894 48 29 2,000 6,953E-04 0,01248459 GO:0048871|multicellular organismal homeostasis, ! cellular hormone metabolic process GO:0034754 113 67 3,000 7,199E-04 0,01283106 ! hexose catabolic process GO:0019320 104 67 3,000 7,199E-04 0,01273671 ! regulation of helicase activity GO:0051095 15 7 1,000 7,395E-04 0,01298742 ! cytokinesis during cell cycle GO:0033205 11 7 1,000 7,395E-04 0,01289331 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 7,395E-04 0,01280055 ! oxaloacetate metabolic process GO:0006107 10 7 1,000 7,395E-04 0,01270912 ! organ growth GO:0035265 15 7 1,000 7,395E-04 0,01261898 ! positive regulation of mitotic cell cycle GO:0045931 12 7 1,000 7,395E-04 0,01253012 ! centrosome duplication GO:0051298 13 7 1,000 7,395E-04 0,01244249 ! G1 DNA damage checkpoint GO:0031571 21 7 1,000 7,395E-04 0,01235609 ! cranial nerve morphogenesis GO:0021602 11 7 1,000 7,395E-04 0,01227087 ! response to tumor cell GO:0002347 13 7 1,000 7,395E-04 0,01218682 ! regulation of respiratory burst GO:0060263 11 7 1,000 7,395E-04 0,01210392 ! peptidyl-threonine modification GO:0018210 25 7 1,000 7,395E-04 0,01202214 ! regulation of protein homodimerization activity GO:0043496 18 7 1,000 7,395E-04 0,01194145 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 3,000 7,614E-04 0,01221264 ! cell junction assembly GO:0034329 78 30 2,000 7,692E-04 0,01225586 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 3,000 8,045E-04 0,01273413 ! reproductive structure development GO:0048608 113 71 3,000 8,958E-04 0,01408681 ! metanephros development GO:0001656 74 32 2,000 9,314E-04 0,0145521 ! negative regulation of MAP kinase activity GO:0043407 69 32 2,000 9,314E-04 0,01445822 ! positive regulation of catabolic process GO:0009896 64 32 2,000 9,314E-04 0,01436554 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 3,000 9,441E-04 0,01446789 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 3,000 9,441E-04 0,01437632 ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 1,000 9,821E-04 0,01486157 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 1,000 9,821E-04 0,01476869 ! pigment granule organization GO:0048753 16 8 1,000 9,821E-04 0,01467696 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 9,821E-04 0,01458636 ! ER overload response GO:0006983 12 8 1,000 9,821E-04 0,01449687 ! regulation of pigmentation during development GO:0048070 24 8 1,000 9,821E-04 0,01440848 ! melanin metabolic process GO:0006582 15 8 1,000 9,821E-04 0,01432115 ! response to UV-B GO:0010224 16 8 1,000 9,821E-04 0,01423488 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 1,000 9,821E-04 0,01414964 ! blastocyst growth GO:0001832 19 8 1,000 9,821E-04 0,01406542 ! leukocyte chemotaxis GO:0030595 50 33 2,000 1,02E-03 0,0145224 GO:0060326|cell chemotaxis, ! negative regulation of protein transport GO:0051224 69 33 2,000 1,02E-03 0,01443697 ! cell-matrix adhesion GO:0007160 163 75 3,000 1,1E-03 0,01547581 ! lymphocyte differentiation GO:0030098 167 75 3,000 1,1E-03 0,01538583 ! regulation of striated muscle tissue development GO:0016202 69 34 2,000 1,114E-03 0,01549111 ! development of primary sexual characteristics GO:0045137 124 76 3,000 1,156E-03 0,01597939 ! steroid biosynthetic process GO:0006694 131 76 3,000 1,156E-03 0,01588808 ! monosaccharide catabolic process GO:0046365 115 76 3,000 1,156E-03 0,0157978 ! regulation of catabolic process GO:0009894 161 76 3,000 1,156E-03 0,01570855 ! regulation of muscle development GO:0048634 70 35 2,000 1,213E-03 0,01639508 ! negative regulation of DNA metabolic process GO:0051053 61 35 2,000 1,213E-03 0,01630349 ! female gonad development GO:0008585 58 35 2,000 1,213E-03 0,01621292 ! regulation of microtubule-based process GO:0032886 78 35 2,000 1,213E-03 0,01612334 ! positive regulation of ligase activity GO:0051351 124 77 3,000 1,213E-03 0,01603929 ! regulation of developmental growth GO:0048638 15 9 1,000 1,258E-03 0,0165362 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 1,258E-03 0,01644633 ! regulation of glycolysis GO:0006110 21 9 1,000 1,258E-03 0,01635744 ! T cell selection GO:0045058 23 9 1,000 1,258E-03 0,01626949 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 1,000 1,258E-03 0,01618249 ! receptor clustering GO:0043113 18 9 1,000 1,258E-03 0,01609641 ! behavioral fear response GO:0001662 22 9 1,000 1,258E-03 0,01601125 GO:0002209|behavioral defense response, ! motor axon guidance GO:0008045 16 9 1,000 1,258E-03 0,01592698 ! protein heterooligomerization GO:0051291 16 9 1,000 1,258E-03 0,01584359 ! alpha-beta T cell differentiation GO:0046632 21 9 1,000 1,258E-03 0,01576107 ! regulation of mitochondrial membrane potential GO:0051881 17 9 1,000 1,258E-03 0,01567941 ! response to steroid hormone stimulus GO:0048545 137 78 3,000 1,273E-03 0,01578691 ! cell junction organization GO:0034330 86 36 2,000 1,317E-03 0,01625455 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 3,000 1,335E-03 0,01638282 ! protein import into nucleus GO:0006606 158 80 3,000 1,398E-03 0,01707793 ! regulation of protein stability GO:0031647 73 37 2,000 1,427E-03 0,01734424 ! T cell activation GO:0042110 168 81 3,000 1,464E-03 0,01770204 ! cell-substrate adhesion GO:0031589 171 81 3,000 1,464E-03 0,01761353 ! nuclear import GO:0051170 161 81 3,000 1,464E-03 0,0175259 ! response to drug GO:0042493 143 82 3,000 1,532E-03 0,01824843 ! cellular response to hormone stimulus GO:0032870 167 82 3,000 1,532E-03 0,01815854 ! mitotic cell cycle checkpoint GO:0007093 76 38 2,000 1,543E-03 0,01819677 ! development of primary female sexual characteristics GO:0046545 67 38 2,000 1,543E-03 0,01810801 GO:0046660|female sex differentiation, ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 1,000 1,566E-03 0,01828989 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 1,566E-03 0,01820153 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 1,000 1,566E-03 0,01811403 ! negative regulation of striated muscle development GO:0045843 19 10 1,000 1,566E-03 0,01802736 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 1,000 1,566E-03 0,01794151 ! B cell proliferation GO:0042100 18 10 1,000 1,566E-03 0,01785648 ! multicellular organism growth GO:0035264 18 10 1,000 1,566E-03 0,01777225 ! alpha-beta T cell activation GO:0046631 23 10 1,000 1,566E-03 0,01768881 ! midbrain development GO:0030901 13 10 1,000 1,566E-03 0,01760616 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 1,000 1,566E-03 0,01752427 GO:0043470|regulation of carbohydrate catabolic process, ! response to nicotine GO:0035094 20 10 1,000 1,566E-03 0,01744314 ! mammary gland development GO:0030879 86 39 2,000 1,664E-03 0,01845084 ! development of primary male sexual characteristics GO:0046546 66 39 2,000 1,664E-03 0,0183662 ! regulation of ligase activity GO:0051340 142 84 3,000 1,674E-03 0,01839655 ! cytokinesis GO:0000910 72 40 2,000 1,791E-03 0,01958849 ! protein localization in nucleus GO:0034504 176 87 3,000 1,905E-03 0,02073939 ! negative regulation of muscle development GO:0048635 20 11 1,000 1,906E-03 0,0206613 ! regulation of intracellular pH GO:0051453 19 11 1,000 1,906E-03 0,02056865 ! negative regulation of ossification GO:0030279 26 11 1,000 1,906E-03 0,02047683 ! thymus development GO:0048538 27 11 1,000 1,906E-03 0,02038582 ! regulation of embryonic development GO:0045995 27 11 1,000 1,906E-03 0,02029562 ! female gamete generation GO:0007292 61 41 2,000 1,924E-03 0,02039334 ! dorsal/ventral pattern formation GO:0009953 68 41 2,000 1,924E-03 0,02030389 ! gland development GO:0048732 206 88 3,000 1,986E-03 0,02087082 ! regulation of intracellular protein transport GO:0033157 80 42 2,000 2,063E-03 0,02158051 ! sex differentiation GO:0007548 145 90 3,000 2,157E-03 0,02246188 ! neural tube development GO:0021915 77 43 2,000 2,208E-03 0,0228982 ! regulation of epithelial cell proliferation GO:0050678 111 43 2,000 2,208E-03 0,02279993 ! positive regulation of cellular catabolic process GO:0031331 31 12 1,000 2,279E-03 0,02342929 ! virus-host interaction GO:0019048 29 12 1,000 2,279E-03 0,02332959 ! regulation of B cell proliferation GO:0030888 20 12 1,000 2,279E-03 0,02323074 ! dopamine receptor signaling pathway GO:0007212 28 12 1,000 2,279E-03 0,02313272 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 1,000 2,279E-03 0,02303552 ! fear response GO:0042596 26 12 1,000 2,279E-03 0,02293914 ! cranial nerve development GO:0021545 20 12 1,000 2,279E-03 0,02284356 ! autonomic nervous system development GO:0048483 24 12 1,000 2,279E-03 0,02274877 ! gland morphogenesis GO:0022612 29 12 1,000 2,279E-03 0,02265477 ! T cell homeostasis GO:0043029 25 12 1,000 2,279E-03 0,02256154 ! digestive tract morphogenesis GO:0048546 26 12 1,000 2,279E-03 0,02246907 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! negative regulation of mast cell proliferation GO:0070667 23 12 1,000 2,279E-03 0,02237736 GO:0042130|negative regulation of T cell proliferation, ! regulation of defense response GO:0031347 149 92 3,000 2,336E-03 0,02285177 ! male sex differentiation GO:0046661 76 44 2,000 2,359E-03 0,02298016 ! double-strand break repair GO:0006302 81 44 2,000 2,359E-03 0,0228875 ! B cell differentiation GO:0030183 107 44 2,000 2,359E-03 0,02279558 ! developmental growth GO:0048589 82 44 2,000 2,359E-03 0,0227044 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 3,000 2,43E-03 0,02329483 GO:0010498|proteasomal protein catabolic process, ! leukocyte migration GO:0050900 68 45 2,000 2,517E-03 0,02402731 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 2,000 2,68E-03 0,02548986 ! regulation of gene-specific transcription GO:0032583 96 46 2,000 2,68E-03 0,0253895 ! negative regulation of cell migration GO:0030336 115 46 2,000 2,68E-03 0,02528994 ! pigmentation GO:0043473 100 46 2,000 2,68E-03 0,02519115 ! double-strand break repair via homologous recombination GO:0000724 19 13 1,000 2,682E-03 0,02511171 GO:0000725|recombinational repair, ! regulation of skeletal muscle fiber development GO:0048742 32 13 1,000 2,682E-03 0,02501438 ! cellular carbohydrate catabolic process GO:0044275 15 13 1,000 2,682E-03 0,0249178 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 1,000 2,682E-03 0,02482196 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 1,000 2,682E-03 0,02472686 ! regulation of cellular pH GO:0030641 22 13 1,000 2,682E-03 0,02463248 ! cytoplasmic sequestering of protein GO:0051220 24 13 1,000 2,682E-03 0,02453882 ! leukocyte differentiation GO:0002521 202 96 3,000 2,727E-03 0,02485071 ! regulation of DNA metabolic process GO:0051052 178 97 3,000 2,831E-03 0,02570233 ! hormone metabolic process GO:0042445 157 97 3,000 2,831E-03 0,02560571 ! regulation of protein localization GO:0032880 176 97 3,000 2,831E-03 0,02550981 ! positive regulation of cell cycle GO:0045787 89 48 2,000 3,027E-03 0,02717782 ! mitochondrial transport GO:0006839 82 48 2,000 3,027E-03 0,02707678 ! regulation of mast cell proliferation GO:0070666 81 48 2,000 3,027E-03 0,0269765 ! regulation of S phase GO:0033261 23 14 1,000 3,117E-03 0,02767398 ! hair follicle morphogenesis GO:0031069 26 14 1,000 3,117E-03 0,02757224 ! regulation of mRNA processing GO:0050684 24 14 1,000 3,117E-03 0,02747124 ! actin cytoskeleton reorganization GO:0031532 33 14 1,000 3,117E-03 0,02737098 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 1,000 3,117E-03 0,02727145 GO:0060675|ureteric bud morphogenesis, ! T cell differentiation in the thymus GO:0033077 31 14 1,000 3,117E-03 0,02717264 ! induction of apoptosis by extracellular signals GO:0008624 89 49 2,000 3,211E-03 0,02788704 ! histone modification GO:0016570 91 50 2,000 3,401E-03 0,02943098 ! regulation of skeletal muscle tissue development GO:0048641 35 15 1,000 3,582E-03 0,03089372 ! negative regulation of bone remodeling GO:0046851 33 15 1,000 3,582E-03 0,03078338 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 1,000 3,582E-03 0,03067383 ! G1/S transition checkpoint GO:0031575 40 15 1,000 3,582E-03 0,03056506 ! intermediate filament cytoskeleton organization GO:0045104 31 15 1,000 3,582E-03 0,03045706 ! regulation of ATPase activity GO:0043462 21 15 1,000 3,582E-03 0,03034981 ! lymphocyte homeostasis GO:0002260 30 15 1,000 3,582E-03 0,03024332 ! response to estrogen stimulus GO:0043627 93 51 2,000 3,597E-03 0,03026273 ! regulation of leukocyte proliferation GO:0070663 88 51 2,000 3,597E-03 0,03015728 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! epithelial tube morphogenesis GO:0060562 98 51 2,000 3,597E-03 0,03005257 ! regulation of muscle contraction GO:0006937 81 52 2,000 3,801E-03 0,03164315 ! positive regulation of growth GO:0045927 90 52 2,000 3,801E-03 0,03153404 ! covalent chromatin modification GO:0016569 101 52 2,000 3,801E-03 0,03142568 ! cartilage development GO:0051216 90 52 2,000 3,801E-03 0,03131805 ! regulation of neuron apoptosis GO:0043523 100 53 2,000 4,011E-03 0,03293917 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 4,078E-03 0,03337377 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 1,000 4,078E-03 0,03326064 ! activation of MAPKK activity GO:0000186 35 16 1,000 4,078E-03 0,03314827 ! negative regulation of microtubule depolymerization GO:0007026 46 16 1,000 4,078E-03 0,03303666 GO:0031114|regulation of microtubule depolymerization, ! intermediate filament-based process GO:0045103 32 16 1,000 4,078E-03 0,0329258 ! axon cargo transport GO:0008088 43 16 1,000 4,078E-03 0,03281568 ! positive regulation of protein import into nucleus GO:0042307 30 16 1,000 4,078E-03 0,0327063 ! negative regulation of tissue remodeling GO:0034104 36 16 1,000 4,078E-03 0,03259764 ! negative regulation of leukocyte proliferation GO:0070664 31 16 1,000 4,078E-03 0,0324897 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 4,078E-03 0,03238247 ! defense response to virus GO:0051607 37 16 1,000 4,078E-03 0,03227595 ! regulation of protein catabolic process GO:0042176 116 55 2,000 4,453E-03 0,03512842 ! negative regulation of cell motion GO:0051271 134 55 2,000 4,453E-03 0,03501362 ! metencephalon development GO:0022037 30 17 1,000 4,604E-03 0,03607938 ! negative regulation of cell cycle process GO:0010948 32 17 1,000 4,604E-03 0,03596224 ! regulation of viral genome replication GO:0045069 28 17 1,000 4,604E-03 0,03584586 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 1,000 4,604E-03 0,03573022 ! NAD metabolic process GO:0019674 29 17 1,000 4,604E-03 0,03561534 ! negative regulation of protein catabolic process GO:0042177 40 17 1,000 4,604E-03 0,03550119 ! regulation of protein binding GO:0043393 33 17 1,000 4,604E-03 0,03538776 ! negative regulation of homeostatic process GO:0032845 33 17 1,000 4,604E-03 0,03527506 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 1,000 4,604E-03 0,03516308 ! nucleotide-excision repair GO:0006289 83 56 2,000 4,685E-03 0,03566827 ! positive regulation of cell migration GO:0030335 126 57 2,000 4,923E-03 0,03736715 ! regulation of intracellular transport GO:0032386 101 57 2,000 4,923E-03 0,03724964 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 5,159E-03 0,03890875 ! protein amino acid ADP-ribosylation GO:0006471 33 18 1,000 5,159E-03 0,03878716 ! centrosome cycle GO:0007098 25 18 1,000 5,159E-03 0,03866633 ! epidermis morphogenesis GO:0048730 40 18 1,000 5,159E-03 0,03854624 ! peptidyl-serine phosphorylation GO:0018105 38 18 1,000 5,159E-03 0,03842691 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 1,000 5,159E-03 0,0383083 ! nerve development GO:0021675 28 18 1,000 5,159E-03 0,03819043 ! regulation of heart contraction GO:0008016 110 60 2,000 5,683E-03 0,04194089 ! protein amino acid autophosphorylation GO:0046777 141 60 2,000 5,683E-03 0,04181263 ! negative regulation of response to stimulus GO:0048585 100 60 2,000 5,683E-03 0,04168516 ! kidney development GO:0001822 122 60 2,000 5,683E-03 0,04155845 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 1,000 5,743E-03 0,0418714 ! lipid phosphorylation GO:0046834 35 19 1,000 5,743E-03 0,0417449 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 1,000 5,743E-03 0,04161916 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 1,000 5,743E-03 0,04149418 ! actin filament bundle formation GO:0051017 42 19 1,000 5,743E-03 0,04136995 ! neuromuscular junction development GO:0007528 34 19 1,000 5,743E-03 0,04124645 ! cellular pigmentation GO:0033059 36 19 1,000 5,743E-03 0,0411237 ! proximal/distal pattern formation GO:0009954 32 19 1,000 5,743E-03 0,04100167 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 1,000 6,356E-03 0,04524409 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 1,000 6,356E-03 0,04511063 ! regulation of carbohydrate metabolic process GO:0006109 38 20 1,000 6,356E-03 0,04497795 GO:0010675|regulation of cellular carbohydrate metabolic process, ! response to alkaloid GO:0043279 38 20 1,000 6,356E-03 0,04484605 ! cellular response to starvation GO:0009267 33 20 1,000 6,356E-03 0,04471492 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 1,000 6,356E-03 0,04458455 ! peptidyl-serine modification GO:0018209 43 20 1,000 6,356E-03 0,04445495 ! negative regulation of T cell activation GO:0050868 40 20 1,000 6,356E-03 0,04432609 ! negative regulation of translation GO:0017148 29 20 1,000 6,356E-03 0,04419798 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 1,000 6,356E-03 0,04407061 ! positive regulation of cell motion GO:0051272 146 64 2,000 6,799E-03 0,0470073 ! glycerol metabolic process GO:0006071 34 21 1,000 6,997E-03 0,04824022 ! hindlimb morphogenesis GO:0035137 43 21 1,000 6,997E-03 0,04810239 ! ovarian follicle development GO:0001541 35 21 1,000 6,997E-03 0,04796535 ! negative regulation of intracellular transport GO:0032387 41 21 1,000 6,997E-03 0,04782908 ! response to cytokine stimulus GO:0034097 63 21 1,000 6,997E-03 0,04769359 ! collagen catabolic process GO:0030574 28 21 1,000 6,997E-03 0,04755886 ! gut development GO:0048565 39 21 1,000 6,997E-03 0,04742489 ! embryonic limb morphogenesis GO:0030326 125 65 2,000 7,097E-03 0,04796448 GO:0035113|embryonic appendage morphogenesis, ! secondary metabolic process GO:0019748 116 66 2,000 7,403E-03 0,04988948 ! positive regulation of protein catabolic process GO:0045732 38 22 1,000 7,667E-03 0,0515271 ! microtubule-based transport GO:0010970 54 22 1,000 7,667E-03 0,05138357 ! glutamate signaling pathway GO:0007215 41 22 1,000 7,667E-03 0,05124083 ! regeneration GO:0031099 41 22 1,000 7,667E-03 0,05109889 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 1,000 7,667E-03 0,05095773 ! ureteric bud development GO:0001657 43 22 1,000 7,667E-03 0,05081736 ! renal system process GO:0003014 41 22 1,000 7,667E-03 0,05067775 ! positive regulation of intracellular transport GO:0032388 37 22 1,000 7,667E-03 0,0505389 ! positive regulation of B cell activation GO:0050871 38 22 1,000 7,667E-03 0,05040082 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 1,000 7,667E-03 0,05026349 ! protein stabilization GO:0050821 39 22 1,000 7,667E-03 0,0501269 ! chromosome segregation GO:0007059 113 67 2,000 7,716E-03 0,05030953 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 2,000 7,716E-03 0,05017356 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 2,000 7,716E-03 0,05003832 ! negative regulation of ligase activity GO:0051352 112 68 2,000 8,037E-03 0,05197978 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! positive regulation of DNA replication GO:0045740 43 23 1,000 8,364E-03 0,05395237 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 8,364E-03 0,05380811 ! gluconeogenesis GO:0006094 33 23 1,000 8,364E-03 0,05366462 ! regulation of cell-matrix adhesion GO:0001952 78 23 1,000 8,364E-03 0,0535219 GO:0010810|regulation of cell-substrate adhesion, ! response to ethanol GO:0045471 46 23 1,000 8,364E-03 0,05337993 ! activation of pro-apoptotic gene products GO:0008633 47 23 1,000 8,364E-03 0,05323871 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 1,000 8,364E-03 0,05309824 ! regulation of viral reproduction GO:0050792 38 23 1,000 8,364E-03 0,05295851 ! negative regulation of catabolic process GO:0009895 50 23 1,000 8,364E-03 0,05281951 ! acetyl-CoA catabolic process GO:0046356 36 23 1,000 8,364E-03 0,05268124 GO:0006099|tricarboxylic acid cycle, ! urogenital system development GO:0001655 137 69 2,000 8,366E-03 0,05255203 ! appendage morphogenesis GO:0035107 135 70 2,000 8,702E-03 0,05452386 GO:0035108|limb morphogenesis, ! appendage development GO:0048736 136 71 2,000 9,046E-03 0,05653448 GO:0060173|limb development, ! B cell activation GO:0042113 160 71 2,000 9,046E-03 0,05638802 ! protein import into nucleus, translocation GO:0000060 46 24 1,000 9,089E-03 0,05650539 ! positive regulation of fibroblast proliferation GO:0048146 43 24 1,000 9,089E-03 0,05635976 ! regulation of cellular catabolic process GO:0031329 52 24 1,000 9,089E-03 0,05621488 ! multicellular organismal response to stress GO:0033555 49 24 1,000 9,089E-03 0,05607074 ! lymphocyte proliferation GO:0046651 48 24 1,000 9,089E-03 0,05592733 ! leukocyte homeostasis GO:0001776 44 24 1,000 9,089E-03 0,05578466 ! alditol metabolic process GO:0019400 38 24 1,000 9,089E-03 0,05564272 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 2,000 9,399E-03 0,0573943 ! learning or memory GO:0007611 147 73 2,000 9,759E-03 0,059443 ! myelination GO:0042552 45 25 1,000 9,84E-03 0,05978767 ! dicarboxylic acid metabolic process GO:0043648 42 25 1,000 9,84E-03 0,05963707 ! vasculogenesis GO:0001570 46 25 1,000 9,84E-03 0,05948723 ! receptor metabolic process GO:0043112 46 25 1,000 9,84E-03 0,05933814 ! response to starvation GO:0042594 42 25 1,000 9,84E-03 0,05918979 ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 9,84E-03 0,05904219 ! coenzyme catabolic process GO:0009109 39 25 1,000 9,84E-03 0,05889532 ! negative regulation of cell development GO:0010721 73 25 1,000 9,84E-03 0,05874918 GO:0050768|negative regulation of neurogenesis, ! interaction with host GO:0051701 62 25 1,000 9,84E-03 0,05860376 ! somitogenesis GO:0001756 43 25 1,000 9,84E-03 0,05845906 ! cellular response to nutrient levels GO:0031669 41 25 1,000 9,84E-03 0,05831507 ! neural tube closure GO:0001843 49 25 1,000 9,84E-03 0,05817179 GO:0060606|tube closure, ! regulation of transcription factor activity GO:0051090 126 74 2,000 0,01012708 0,05971997 GO:0090046|regulation of transcription regulator activity, ! eye development GO:0001654 143 74 2,000 0,01012708 0,05957395 ! phosphoinositide-mediated signaling GO:0048015 131 75 2,000 0,01050321 0,06163591 ! pyruvate metabolic process GO:0006090 38 26 1,000 0,01061862 0,06216154 ! acetyl-CoA metabolic process GO:0006084 39 26 1,000 0,01061862 0,06201066 ! molting cycle process GO:0022404 50 26 1,000 0,01061862 0,06186051 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 1,000 0,01061862 0,06171109 ! regulation of transcription factor import into nucleus GO:0042990 54 26 1,000 0,01061862 0,06156239 ! microtubule organizing center organization GO:0031023 39 26 1,000 0,01061862 0,0614144 GO:0051297|centrosome organization, ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 1,000 0,01061862 0,06126712 ! positive regulation of nuclear division GO:0051785 40 26 1,000 0,01061862 0,06112055 GO:0045840|positive regulation of mitosis, ! blastocyst development GO:0001824 49 26 1,000 0,01061862 0,06097468 ! leukocyte proliferation GO:0070661 52 26 1,000 0,01061862 0,0608295 GO:0032943|mononuclear cell proliferation, ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 1,000 0,01142318 0,06528308 ! multicellular organismal catabolic process GO:0044243 36 27 1,000 0,01142318 0,06512839 ! response to toxin GO:0009636 47 27 1,000 0,01142318 0,06497442 ! primary neural tube formation GO:0014020 51 27 1,000 0,01142318 0,06482118 ! base-excision repair GO:0006284 41 27 1,000 0,01142318 0,06466866 ! regulation of chromosome organization GO:0033044 42 27 1,000 0,01142318 0,06451685 ! negative regulation of lymphocyte activation GO:0051250 53 27 1,000 0,01142318 0,06436576 ! negative regulation of organelle organization GO:0010639 161 78 2,000 0,01167981 0,06565802 ! protein oligomerization GO:0051259 139 78 2,000 0,01167981 0,06550497 ! positive regulation of phosphorylation GO:0042327 129 79 2,000 0,01208818 0,06763757 ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 0,01225372 0,06840478 ! peptidyl-tyrosine modification GO:0018212 50 28 1,000 0,01225372 0,06824644 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 2,000 0,0129293 0,07184273 GO:0045937|positive regulation of phosphate metabolic process, ! response to hypoxia GO:0001666 171 81 2,000 0,0129293 0,07167719 ! regulation of pH GO:0006885 43 29 1,000 0,0131099 0,07251132 ! negative regulation of neuron apoptosis GO:0043524 56 29 1,000 0,0131099 0,07234501 ! response to nutrient GO:0007584 125 82 2,000 0,01336211 0,07356804 ! response to oxygen levels GO:0070482 176 83 2,000 0,0138031 0,07582254 ! positive regulation of multicellular organism growth GO:0040018 51 30 1,000 0,01399138 0,0766817 ! ensheathment of neurons GO:0007272 57 30 1,000 0,01399138 0,07650743 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 1,000 0,01399138 0,07633394 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 1,000 0,01399138 0,07616124 ! negative regulation of leukocyte activation GO:0002695 56 30 1,000 0,01399138 0,07598932 ! regulation of B cell activation GO:0050864 50 30 1,000 0,01399138 0,07581817 ! response to heat GO:0009408 50 30 1,000 0,01399138 0,07564779 ! alkaloid metabolic process GO:0009820 53 31 1,000 0,01489783 0,08036814 ! collagen metabolic process GO:0032963 45 31 1,000 0,01489783 0,08018835 ! cholesterol homeostasis GO:0042632 53 31 1,000 0,01489783 0,08000935 GO:0055092|sterol homeostasis, ! ovulation cycle process GO:0022602 49 31 1,000 0,01489783 0,07983116 ! negative regulation of transcription regulator activity GO:0090048 58 31 1,000 0,01489783 0,07965376 GO:0043433|negative regulation of transcription factor activity, ! tube morphogenesis GO:0035239 176 86 2,000 0,01517543 0,08095807 ! mitochondrion organization GO:0007005 148 86 2,000 0,01517543 0,08077896 ! regulation of protein transport GO:0051223 154 87 2,000 0,01564938 0,08311788 GO:0070201|regulation of establishment of protein localization, ! response to hydrogen peroxide GO:0042542 50 32 1,000 0,01582893 0,08388635 ! spindle organization GO:0007051 46 32 1,000 0,01582893 0,08370198 ! regulation of protein import into nucleus GO:0042306 63 32 1,000 0,01582893 0,08351842 ! hexose biosynthetic process GO:0019319 48 32 1,000 0,01582893 0,08333567 ! ovulation cycle GO:0042698 51 32 1,000 0,01582893 0,08315371 ! peripheral nervous system development GO:0007422 64 32 1,000 0,01582893 0,08297255 ! positive regulation of protein modification process GO:0031401 136 88 2,000 0,0161316 0,08437526 ! regulation of DNA binding GO:0051101 155 88 2,000 0,0161316 0,08419224 ! regulation of cell adhesion GO:0030155 212 89 2,000 0,01662211 0,08656448 ! post-embryonic development GO:0009791 69 33 1,000 0,01678434 0,08722056 ! positive regulation of gene-specific transcription GO:0043193 65 33 1,000 0,01678434 0,08703258 ! pyridine nucleotide metabolic process GO:0019362 55 33 1,000 0,01678434 0,08684542 ! ossification GO:0001503 188 90 2,000 0,01712092 0,08839685 ! regulation of cell cycle process GO:0010564 149 90 2,000 0,01712092 0,08820756 ! bone development GO:0060348 189 91 2,000 0,01762804 0,09062622 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 1,000 0,01776374 0,09112914 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 1,000 0,01776374 0,09093525 ! positive regulation of MAP kinase activity GO:0043406 160 93 2,000 0,01866727 0,09535763 ! regulation of membrane potential GO:0042391 164 93 2,000 0,01866727 0,0951556 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 1,000 0,01876682 0,09546083 ! regulation of synaptic plasticity GO:0048167 64 35 1,000 0,01876682 0,09525944 ! embryonic skeletal system morphogenesis GO:0048704 59 35 1,000 0,01876682 0,09505889 ! negative regulation of hydrolase activity GO:0051346 62 35 1,000 0,01876682 0,09485919 ! calcium-mediated signaling GO:0019722 62 35 1,000 0,01876682 0,09466032 ! cytokine production GO:0001816 59 35 1,000 0,01876682 0,09446229 ! neural tube formation GO:0001841 67 35 1,000 0,01876682 0,09426508 ! mitotic sister chromatid segregation GO:0000070 57 36 1,000 0,01979326 0,09921371 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 1,000 0,01979326 0,09900745 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! maintenance of protein location in cell GO:0032507 86 36 1,000 0,01979326 0,09880204 ! positive regulation of cell development GO:0010720 80 36 1,000 0,01979326 0,09859748 ! aerobic respiration GO:0009060 55 36 1,000 0,01979326 0,09839377 ! androgen receptor signaling pathway GO:0030521 74 36 1,000 0,01979326 0,09819089 ! monosaccharide biosynthetic process GO:0046364 52 36 1,000 0,01979326 0,09798885 ! negative regulation of cell activation GO:0050866 65 36 1,000 0,01979326 0,09778764 ! sister chromatid segregation GO:0000819 58 37 1,000 0,02084274 0,10276155 ! monovalent inorganic cation homeostasis GO:0055067 58 37 1,000 0,02084274 0,1025514 ! negative regulation of DNA binding GO:0043392 68 37 1,000 0,02084274 0,10234211 ! pigment metabolic process GO:0042440 80 37 1,000 0,02084274 0,10213368 ! positive regulation of DNA metabolic process GO:0051054 72 38 1,000 0,02191496 0,10716948 ! carbohydrate homeostasis GO:0033500 53 38 1,000 0,02191496 0,1069521 GO:0042593|glucose homeostasis, ! lipid homeostasis GO:0055088 67 38 1,000 0,02191496 0,1067356 ! embryonic epithelial tube formation GO:0001838 72 38 1,000 0,02191496 0,10651997 ! positive regulation of leukocyte proliferation GO:0070665 62 38 1,000 0,02191496 0,10630521 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! skeletal muscle tissue development GO:0007519 186 99 2,000 0,02198521 0,10643142 GO:0060538|skeletal muscle organ development, ! learning GO:0007612 77 39 1,000 0,0230096 0,11116685 ! segmentation GO:0035282 67 39 1,000 0,0230096 0,11094407 ! regulation of action potential in neuron GO:0019228 73 39 1,000 0,0230096 0,11072218 ! negative regulation of binding GO:0051100 72 40 1,000 0,02412636 0,11586431 ! multicellular organismal metabolic process GO:0044236 57 40 1,000 0,02412636 0,1156335 ! mesenchymal cell development GO:0014031 87 40 1,000 0,02412636 0,11540361 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! maintenance of protein location GO:0045185 91 40 1,000 0,02412636 0,11517464 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 1,000 0,02526494 0,12037117 ! cellular amide metabolic process GO:0043603 67 41 1,000 0,02526494 0,12013328 ! regulation of T cell proliferation GO:0042129 71 41 1,000 0,02526494 0,11989633 ! regulation of T cell differentiation GO:0045580 70 41 1,000 0,02526494 0,11966031 ! polyol metabolic process GO:0019751 66 41 1,000 0,02526494 0,11942523 ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 0,02642504 0,12466399 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 1,000 0,02642504 0,12442003 ! negative regulation of protein complex disassembly GO:0043242 101 42 1,000 0,02642504 0,12417702 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 1,000 0,02642504 0,12393496 ! alcohol biosynthetic process GO:0046165 59 42 1,000 0,02642504 0,12369384 ! neuron migration GO:0001764 79 42 1,000 0,02642504 0,12345366 ! epithelial cell differentiation GO:0030855 79 43 1,000 0,02760636 0,12872266 ! receptor-mediated endocytosis GO:0006898 88 43 1,000 0,02760636 0,12847368 ! glucose transport GO:0015758 65 43 1,000 0,02760636 0,12822566 ! hexose transport GO:0008645 67 44 1,000 0,0288086 0,13355203 GO:0015749|monosaccharide transport, ! maintenance of location in cell GO:0051651 97 44 1,000 0,0288086 0,1332952 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,0296924 0,13712075 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,0296924 0,13685806 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,0296924 0,13659638 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,0296924 0,1363357 ! neuron fate determination GO:0048664 7 5 0,000 0,0296924 0,13607602 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,0296924 0,13581732 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,0296924 0,1355596 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,0296924 0,13530286 ! polyol transport GO:0015791 12 5 0,000 0,0296924 0,13504709 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,0296924 0,13479228 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,0296924 0,13453843 ! response to superoxide GO:0000303 10 5 0,000 0,0296924 0,13428554 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,0296924 0,1340336 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,0296924 0,1337826 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,0296924 0,13353254 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,0296924 0,13328341 ! female meiosis GO:0007143 7 5 0,000 0,0296924 0,13303521 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,0296924 0,13278793 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,0296924 0,13254158 ! cobalt ion transport GO:0006824 11 5 0,000 0,0296924 0,13229613 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,0296924 0,13205159 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,0296924 0,13180795 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,0296924 0,13156521 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,0296924 0,13132336 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,0296924 0,1310824 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,0296924 0,13084232 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,0296924 0,13060312 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,0296924 0,1303648 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,0296924 0,13012734 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,0296924 0,12989074 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,0296924 0,12965501 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,0296924 0,12942012 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,0296924 0,12918609 ! negative chemotaxis GO:0050919 14 5 0,000 0,0296924 0,1289529 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,0296924 0,12872056 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,0296924 0,12848904 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,0296924 0,12825836 ! behavioral response to pain GO:0048266 9 5 0,000 0,0296924 0,12802851 ! clathrin coat assembly GO:0048268 14 5 0,000 0,0296924 0,12779948 ! Notch receptor processing GO:0007220 8 5 0,000 0,0296924 0,12757127 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,0296924 0,12734387 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! micturition GO:0060073 9 5 0,000 0,0296924 0,12711728 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,0296924 0,12689149 ! copulation GO:0007620 9 5 0,000 0,0296924 0,12666651 ! glial cell fate commitment GO:0021781 13 5 0,000 0,0296924 0,12644232 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,0296924 0,12621892 ! spermidine metabolic process GO:0008216 7 5 0,000 0,0296924 0,12599631 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,0296924 0,12577449 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,0296924 0,12555344 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,0296924 0,12533317 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,0296924 0,12511368 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,0296924 0,12489495 ! grooming behavior GO:0007625 6 5 0,000 0,0296924 0,12467698 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,0296924 0,12445977 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,0296924 0,12424332 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,0296924 0,12402762 ! response to protozoan GO:0001562 10 5 0,000 0,0296924 0,12381267 ! lymph vessel development GO:0001945 10 5 0,000 0,0296924 0,12359846 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,0296924 0,12338499 ! endochondral ossification GO:0001958 16 5 0,000 0,0296924 0,12317226 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,0296924 0,12296026 ! parathyroid gland development GO:0060017 13 5 0,000 0,0296924 0,12274898 ! anagen GO:0042640 6 5 0,000 0,0296924 0,12253844 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,0296924 0,12232861 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,0296924 0,1221195 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,0296924 0,12191111 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,0296924 0,12170342 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,0296924 0,12149644 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,0296924 0,12129017 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,0296924 0,12108459 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,0296924 0,12087971 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,0296924 0,12067552 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,0296924 0,12047202 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,0296924 0,12026921 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,0296924 0,12006707 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,0296924 0,11986562 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,0296924 0,11966484 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,0296924 0,11946473 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,0296924 0,11926529 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 0,0296924 0,11906651 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,0296924 0,1188684 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,0296924 0,11867095 ! histidine catabolic process GO:0006548 6 5 0,000 0,0296924 0,11847414 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,0296924 0,11827799 ! valine metabolic process GO:0006573 10 5 0,000 0,0296924 0,11808249 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,0296924 0,11788764 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,0296924 0,11769342 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,0296924 0,11749985 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,0296924 0,11730691 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,0296924 0,1171146 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,0296924 0,11692293 ! polyol biosynthetic process GO:0046173 5 5 0,000 0,0296924 0,11673188 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,0296924 0,11654145 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,0296924 0,11635164 ! muscle cell migration GO:0014812 8 5 0,000 0,0296924 0,11616245 ! mitochondrial fission GO:0000266 8 5 0,000 0,0296924 0,11597388 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,0296924 0,11578591 ! mRNA transcription GO:0009299 9 5 0,000 0,0296924 0,11559856 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,0296924 0,11541181 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,0296924 0,11522566 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,0296924 0,11504011 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,0296924 0,11485516 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,0296924 0,1146708 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,0296924 0,11448703 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,0296924 0,11430385 ! response to food GO:0032094 6 5 0,000 0,0296924 0,11412126 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,0296924 0,11393925 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,0296924 0,11375782 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,0296924 0,11357696 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,0296924 0,11339668 ! regulation of phospholipase A2 activity GO:0032429 13 5 0,000 0,0296924 0,11321697 ! forebrain neuron development GO:0021884 13 5 0,000 0,0296924 0,11303783 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,0296924 0,11285926 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,0296924 0,11268124 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,0296924 0,11250379 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,0296924 0,1123269 GO:0009251|glucan catabolic process, ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,0296924 0,11215056 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,0296924 0,11197478 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,0296924 0,11179954 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,0296924 0,11162486 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,0296924 0,11145072 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,0296924 0,11127712 ! basic amino acid transport GO:0015802 11 5 0,000 0,0296924 0,11110406 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,0296924 0,11093154 ! depyrimidination GO:0045008 10 5 0,000 0,0296924 0,11075955 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,0296924 0,11058809 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,0296924 0,11041717 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,0296924 0,11024677 GO:0006882|cellular zinc ion homeostasis, ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,0296924 0,1100769 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,0296924 0,10990755 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,0296924 0,10973872 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,0296924 0,10957041 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,0296924 0,10940262 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,0296924 0,10923533 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,0296924 0,10906856 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,0296924 0,1089023 ! response to arsenic GO:0046685 10 5 0,000 0,0296924 0,10873654 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,0296924 0,10857129 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,0296924 0,10840654 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,0296924 0,10824229 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,0296924 0,10807853 ! response to cadmium ion GO:0046686 7 5 0,000 0,0296924 0,10791527 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,0296924 0,1077525 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,0296924 0,10759022 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,0296924 0,10742843 ! decidualization GO:0046697 11 5 0,000 0,0296924 0,10726713 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,0296924 0,10710631 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,0296924 0,10694597 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,0296924 0,10678611 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,0296924 0,10662673 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,0296924 0,10646782 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,0296924 0,10630939 ! embryonic cleavage GO:0040016 6 5 0,000 0,0296924 0,10615142 ! peroxisome fission GO:0016559 5 5 0,000 0,0296924 0,10599393 ! histone demethylation GO:0016577 10 5 0,000 0,0296924 0,1058369 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,0296924 0,10568034 ! mitotic recombination GO:0006312 9 5 0,000 0,0296924 0,10552424 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,0296924 0,1053686 ! metaphase plate congression GO:0051310 7 5 0,000 0,0296924 0,10521342 ! regulation of sterol transport GO:0032371 7 5 0,000 0,0296924 0,10505869 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,0296924 0,10490442 ! enteric nervous system development GO:0048484 8 5 0,000 0,0296924 0,1047506 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,0296924 0,10459723 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,0296924 0,10444431 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,0296924 0,10429184 ! muscle cell proliferation GO:0033002 11 5 0,000 0,0296924 0,10413981 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,0296924 0,10398822 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,0296924 0,10383708 ! plasminogen activation GO:0031639 5 5 0,000 0,0296924 0,10368637 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,0296924 0,1035361 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,0296924 0,10338626 ! metaphase GO:0051323 8 5 0,000 0,0296924 0,10323686 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,0296924 0,10308789 ! cellular response to nutrient GO:0031670 8 5 0,000 0,0296924 0,10293935 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,0296924 0,10279124 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,0296924 0,10264355 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,0296924 0,10249628 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,0296924 0,10234944 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,0296924 0,10220302 ! response to redox state GO:0051775 5 5 0,000 0,0296924 0,10205701 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,0296924 0,10191143 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,0296924 0,10176625 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,0296924 0,10162149 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,0296924 0,10147714 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,0296924 0,1013332 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,0296924 0,10118967 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,0296924 0,10104655 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,0296924 0,10090383 ! striatum development GO:0021756 9 5 0,000 0,0296924 0,10076151 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,0296924 0,10061959 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,0296924 0,10047807 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,0296924 0,10033695 ! glial cell migration GO:0008347 11 5 0,000 0,0296924 0,10019623 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,0296924 0,10005589 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,0296924 0,09991596 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,0296924 0,09977641 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,0296924 0,09963725 ! neuroprotection GO:0043526 6 5 0,000 0,0296924 0,09949848 ! neural plate development GO:0001840 8 5 0,000 0,0296924 0,0993601 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,0296924 0,0992221 ! regulation of sensory perception GO:0051931 7 5 0,000 0,0296924 0,09908448 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,0296924 0,09894724 GO:0046831|regulation of RNA export from nucleus, ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,0296924 0,09881039 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,0296924 0,09867391 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,0296924 0,09853781 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,0296924 0,09840208 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,0296924 0,09826672 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,0296924 0,09813174 ! spindle assembly GO:0051225 6 5 0,000 0,0296924 0,09799713 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,0296924 0,09786289 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,0296924 0,09772901 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,0296924 0,0975955 ! drug metabolic process GO:0017144 6 5 0,000 0,0296924 0,09746236 ! stem cell division GO:0017145 11 5 0,000 0,0296924 0,09732958 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,0296924 0,09719716 ! organ regeneration GO:0031100 7 5 0,000 0,0296924 0,09706509 ! carnitine metabolic process GO:0009437 7 5 0,000 0,0296924 0,09693339 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,0296924 0,09680204 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,0296924 0,09667105 ! branching morphogenesis of a tube GO:0048754 97 45 1,000 0,03003149 0,09764292 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 1,000 0,03003149 0,09751115 ! positive regulation of protein transport GO:0051222 72 46 1,000 0,03127472 0,10141103 ! endosome transport GO:0016197 108 47 1,000 0,03253802 0,10536537 ! positive regulation of DNA binding GO:0043388 73 47 1,000 0,03253802 0,10522375 ! morphogenesis of embryonic epithelium GO:0016331 91 48 1,000 0,03382109 0,10922624 ! activation of caspase activity GO:0006919 84 48 1,000 0,03382109 0,10907983 ! regulation of lymphocyte differentiation GO:0045619 81 48 1,000 0,03382109 0,1089338 ! regulation of action potential GO:0001508 95 49 1,000 0,03512367 0,112978 ! regulation of protein complex disassembly GO:0043244 113 49 1,000 0,03512367 0,11282716 ! response to temperature stimulus GO:0009266 76 49 1,000 0,03512367 0,11267673 ! DNA-dependent DNA replication GO:0006261 74 49 1,000 0,03512367 0,11252669 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,03552481 0,1136605 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,03552481 0,11350956 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,03552481 0,11335902 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,03552481 0,11320887 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,03552481 0,11305913 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,03552481 0,11290977 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,03552481 0,11276082 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,03552481 0,11261225 ! sleep GO:0030431 13 6 0,000 0,03552481 0,11246408 ! response to oxygen radical GO:0000305 11 6 0,000 0,03552481 0,11231629 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,03552481 0,1121689 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,03552481 0,11202189 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,03552481 0,11187526 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,03552481 0,11172902 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,03552481 0,11158316 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,03552481 0,11143768 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,03552481 0,11129258 ! forebrain regionalization GO:0021871 8 6 0,000 0,03552481 0,11114785 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,03552481 0,11100351 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,03552481 0,11085953 ! response to zinc ion GO:0010043 9 6 0,000 0,03552481 0,11071593 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,03552481 0,1105727 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,03552481 0,11042984 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,03552481 0,11028735 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,03552481 0,11014523 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,03552481 0,11000347 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,03552481 0,10986208 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,03552481 0,10972105 ! protein refolding GO:0042026 15 6 0,000 0,03552481 0,10958038 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,03552481 0,10944008 ! opsonization GO:0008228 8 6 0,000 0,03552481 0,10930013 ! mating behavior GO:0007617 7 6 0,000 0,03552481 0,10916054 ! neuron remodeling GO:0016322 15 6 0,000 0,03552481 0,1090213 ! erythrocyte maturation GO:0043249 7 6 0,000 0,03552481 0,10888242 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,03552481 0,10874389 ! equilibrioception GO:0050957 14 6 0,000 0,03552481 0,10860572 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,03552481 0,10846789 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,03552481 0,10833042 ! photoreceptor cell development GO:0042461 10 6 0,000 0,03552481 0,10819329 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,03552481 0,10805651 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,03552481 0,10792007 ! response to interferon-gamma GO:0034341 15 6 0,000 0,03552481 0,10778398 ! toxin metabolic process GO:0009404 11 6 0,000 0,03552481 0,10764824 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,03552481 0,10751283 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,03552481 0,10737776 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,03552481 0,10724304 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,03552481 0,10710865 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,03552481 0,10697459 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,03552481 0,10684087 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,03552481 0,10670749 ! thymic T cell selection GO:0045061 12 6 0,000 0,03552481 0,10657444 ! protein lipoylation GO:0009249 10 6 0,000 0,03552481 0,10644172 ! cysteine metabolic process GO:0006534 10 6 0,000 0,03552481 0,10630933 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,03552481 0,10617727 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,03552481 0,10604553 ! glutamate catabolic process GO:0006538 10 6 0,000 0,03552481 0,10591413 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,03552481 0,10578304 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,03552481 0,10565229 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,03552481 0,10552185 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,03552481 0,10539174 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,03552481 0,10526194 ! hyperosmotic response GO:0006972 9 6 0,000 0,03552481 0,10513247 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,03552481 0,10500332 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,03552481 0,10487448 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,03552481 0,10474595 ! urea metabolic process GO:0019627 7 6 0,000 0,03552481 0,10461775 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,03552481 0,10448985 ! neutrophil activation GO:0042119 8 6 0,000 0,03552481 0,10436227 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,03552481 0,104235 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,03552481 0,10410804 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,03552481 0,10398139 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,03552481 0,10385504 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,03552481 0,103729 ! neuron apoptosis GO:0051402 9 6 0,000 0,03552481 0,10360327 ! nucleoside salvage GO:0043174 9 6 0,000 0,03552481 0,10347784 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,03552481 0,10335272 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,03552481 0,1032279 ! T cell mediated immunity GO:0002456 16 6 0,000 0,03552481 0,10310338 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,03552481 0,10297916 GO:0010543|regulation of platelet activation, ! carnitine transport GO:0015879 10 6 0,000 0,03552481 0,10285523 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,03552481 0,10273161 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,03552481 0,10260828 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,03552481 0,10248525 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,03552481 0,10236251 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,03552481 0,10224007 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,03552481 0,10211792 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,03552481 0,10199606 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,03552481 0,10187449 ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,03552481 0,10175321 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,03552481 0,10163222 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,03552481 0,10151152 ! astrocyte development GO:0014002 15 6 0,000 0,03552481 0,1013911 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,03552481 0,10127097 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,03552481 0,10115112 ! interaction with symbiont GO:0051702 13 6 0,000 0,03552481 0,10103156 ! regulation of dendrite development GO:0050773 16 6 0,000 0,03552481 0,10091228 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,03552481 0,10079328 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,03552481 0,10067456 ! response to copper ion GO:0046688 10 6 0,000 0,03552481 0,10055612 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,03552481 0,10043795 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,03552481 0,10032007 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,03552481 0,10020246 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,03552481 0,10008513 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,03552481 0,09996807 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,03552481 0,09985128 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,03552481 0,09973477 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,03552481 0,09961853 ! hair follicle maturation GO:0048820 7 6 0,000 0,03552481 0,09950256 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,03552481 0,09938686 ! Schwann cell development GO:0014044 15 6 0,000 0,03552481 0,09927143 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,03552481 0,09915626 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,03552481 0,09904137 ! subpallium development GO:0021544 10 6 0,000 0,03552481 0,09892674 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,03552481 0,09881237 ! histone ubiquitination GO:0016574 8 6 0,000 0,03552481 0,09869827 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,03552481 0,09858443 ! maintenance of organ identity GO:0048496 9 6 0,000 0,03552481 0,09847085 ! G2 phase GO:0051319 16 6 0,000 0,03552481 0,09835754 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,03552481 0,09824448 ! establishment of planar polarity GO:0001736 7 6 0,000 0,03552481 0,09813169 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,03552481 0,09801915 ! membrane to membrane docking GO:0022614 14 6 0,000 0,03552481 0,09790687 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,03552481 0,09779485 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,03552481 0,09768308 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,03552481 0,09757157 ! receptor internalization GO:0031623 10 6 0,000 0,03552481 0,09746032 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,03552481 0,09734932 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,03552481 0,09723857 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,03552481 0,09712807 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,03552481 0,09701782 ! protein deubiquitination GO:0016579 14 6 0,000 0,03552481 0,09690782 ! protein destabilization GO:0031648 9 6 0,000 0,03552481 0,09679807 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,03552481 0,09668857 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,03552481 0,09657932 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,03552481 0,09647031 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,03552481 0,09636155 ! progesterone metabolic process GO:0042448 10 6 0,000 0,03552481 0,09625304 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,03552481 0,09614477 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,03552481 0,09603674 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,03552481 0,09592896 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,03552481 0,09582141 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,03552481 0,09571411 ! determination of adult lifespan GO:0008340 15 6 0,000 0,03552481 0,09560705 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,03552481 0,09550022 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,03552481 0,09539364 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,03552481 0,09528729 ! catecholamine transport GO:0051937 9 6 0,000 0,03552481 0,09518118 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,03552481 0,0950753 ! sensory cilium assembly GO:0035058 10 6 0,000 0,03552481 0,09496967 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,03552481 0,09486426 ! maternal placenta development GO:0001893 12 6 0,000 0,03552481 0,09475909 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,03552481 0,09465415 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,03552481 0,09454945 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,03552481 0,09444497 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,03552481 0,09434073 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,03552481 0,09423671 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,03552481 0,09413293 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,03552481 0,09402937 ! regulation of ossification GO:0030278 117 50 1,000 0,03644546 0,0963602 ! negative regulation of immune system process GO:0002683 95 50 1,000 0,03644546 0,09625443 ! positive regulation of binding GO:0051099 78 51 1,000 0,0377862 0,09968597 ! embryonic skeletal system development GO:0048706 85 51 1,000 0,0377862 0,09957679 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 1,000 0,0377862 0,09946784 ! vesicle organization GO:0016050 107 51 1,000 0,0377862 0,09935913 ! regulation of angiogenesis GO:0045765 114 52 1,000 0,03914562 0,10282135 ! morphogenesis of a branching structure GO:0001763 111 52 1,000 0,03914562 0,10270922 ! synapse organization GO:0050808 85 52 1,000 0,03914562 0,10259734 ! cell maturation GO:0048469 100 53 1,000 0,04052343 0,10609291 ! tRNA transcription GO:0009304 14 7 0,000 0,04132236 0,10806696 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,04132236 0,10794962 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,04132236 0,10783254 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,04132236 0,10771571 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,04132236 0,10759914 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,04132236 0,10748281 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,04132236 0,10736674 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,04132236 0,10725092 ! prostate gland development GO:0030850 13 7 0,000 0,04132236 0,10713535 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,04132236 0,10702002 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,04132236 0,10690495 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,04132236 0,10679012 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,04132236 0,10667554 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,04132236 0,1065612 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,04132236 0,10644711 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,04132236 0,10633327 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 0,04132236 0,10621966 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,04132236 0,1061063 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,04132236 0,10599318 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,04132236 0,1058803 ! glycolipid transport GO:0046836 10 7 0,000 0,04132236 0,10576766 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,04132236 0,10565526 GO:0051923|sulfation, ! neuron adhesion GO:0007158 12 7 0,000 0,04132236 0,1055431 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,04132236 0,10543118 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,04132236 0,10531949 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,04132236 0,10520805 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,04132236 0,10509683 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,04132236 0,10498585 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,04132236 0,10487511 ! mRNA stabilization GO:0048255 18 7 0,000 0,04132236 0,1047646 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,04132236 0,10465432 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,04132236 0,10454427 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,04132236 0,10443446 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,04132236 0,10432487 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,04132236 0,10421552 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,04132236 0,10410639 ! lipoprotein transport GO:0042953 14 7 0,000 0,04132236 0,10399749 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,04132236 0,10388882 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,04132236 0,10378038 ! rhythmic behavior GO:0007622 15 7 0,000 0,04132236 0,10367216 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,04132236 0,10356417 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,04132236 0,1034564 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,04132236 0,10334886 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,04132236 0,10324154 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,04132236 0,10313444 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,04132236 0,10302757 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,04132236 0,10292091 ! mechanosensory behavior GO:0007638 14 7 0,000 0,04132236 0,10281448 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,04132236 0,10270827 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,04132236 0,10260227 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,04132236 0,1024965 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,04132236 0,10239094 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,04132236 0,1022856 ! spinal cord patterning GO:0021511 13 7 0,000 0,04132236 0,10218048 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,04132236 0,10207557 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,04132236 0,10197087 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,04132236 0,1018664 ! adrenal gland development GO:0030325 17 7 0,000 0,04132236 0,10176213 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,04132236 0,10165808 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,04132236 0,10155424 ! ovulation GO:0030728 9 7 0,000 0,04132236 0,10145062 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,04132236 0,1013472 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,04132236 0,10124399 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,04132236 0,101141 ! microtubule nucleation GO:0007020 20 7 0,000 0,04132236 0,10103821 ! proline biosynthetic process GO:0006561 10 7 0,000 0,04132236 0,10093564 ! thyroid hormone generation GO:0006590 13 7 0,000 0,04132236 0,10083327 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,04132236 0,10073111 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,04132236 0,10062915 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,04132236 0,1005274 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,04132236 0,10042586 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,04132236 0,10032452 ! galactose metabolic process GO:0006012 13 7 0,000 0,04132236 0,10022339 ! vesicle fusion GO:0006906 17 7 0,000 0,04132236 0,10012246 ! response to dietary excess GO:0002021 8 7 0,000 0,04132236 0,10002173 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,04132236 0,09992121 ! intracellular pH reduction GO:0051452 11 7 0,000 0,04132236 0,09982089 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,04132236 0,09972077 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,04132236 0,09962084 ! purine salvage GO:0043101 10 7 0,000 0,04132236 0,09952112 ! nucleoside transport GO:0015858 8 7 0,000 0,04132236 0,0994216 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,04132236 0,09932228 ! parturition GO:0007567 14 7 0,000 0,04132236 0,09922316 ! rRNA modification GO:0000154 14 7 0,000 0,04132236 0,09912423 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,04132236 0,0990255 ! spindle checkpoint GO:0031577 15 7 0,000 0,04132236 0,09892697 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,04132236 0,09882863 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,04132236 0,09873049 ! macrophage differentiation GO:0030225 11 7 0,000 0,04132236 0,09863254 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,04132236 0,09853479 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,04132236 0,09843723 GO:0046676|negative regulation of insulin secretion, ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,04132236 0,09833986 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,04132236 0,09824269 ! fibrinolysis GO:0042730 10 7 0,000 0,04132236 0,09814571 ! eating behavior GO:0042755 7 7 0,000 0,04132236 0,09804892 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,04132236 0,09795232 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,04132236 0,09785591 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,04132236 0,09775969 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,04132236 0,09766366 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,04132236 0,09756781 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,04132236 0,09747216 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,04132236 0,09737669 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,04132236 0,09728141 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,04132236 0,09718632 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,04132236 0,09709141 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,04132236 0,09699669 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,04132236 0,09690215 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,04132236 0,09680779 ! regulation of meiosis GO:0040020 12 7 0,000 0,04132236 0,09671362 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,04132236 0,09661963 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,04132236 0,09652583 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,04132236 0,0964322 ! oxygen homeostasis GO:0032364 12 7 0,000 0,04132236 0,09633876 ! transcription termination GO:0006353 13 7 0,000 0,04132236 0,0962455 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,04132236 0,09615242 ! anaphase GO:0051322 17 7 0,000 0,04132236 0,09605952 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,04132236 0,0959668 ! axonal fasciculation GO:0007413 18 7 0,000 0,04132236 0,09587426 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,04132236 0,09578189 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,04132236 0,0956897 ! diuresis GO:0030146 12 7 0,000 0,04132236 0,0955977 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,04132236 0,09550586 ! thiamin metabolic process GO:0006772 7 7 0,000 0,04132236 0,09541421 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,04132236 0,09532273 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,04132236 0,09523142 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,04132236 0,09514029 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,04132236 0,09504933 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,04132236 0,09495855 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,04132236 0,09486794 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,04132236 0,09477751 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,04132236 0,09468724 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,04132236 0,09459715 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,04132236 0,09450723 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 10 7 0,000 0,04132236 0,09441748 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,04132236 0,0943279 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,04132236 0,09423849 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,04132236 0,09414925 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,04132236 0,09406017 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,04132236 0,09397127 ! adult feeding behavior GO:0008343 9 7 0,000 0,04132236 0,09388253 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,04132236 0,09379396 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,04132236 0,09370556 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,04132236 0,09361733 ! muscle adaptation GO:0043500 14 7 0,000 0,04132236 0,09352926 ! embryonic heart tube development GO:0035050 10 7 0,000 0,04132236 0,09344136 ! retina homeostasis GO:0001895 12 7 0,000 0,04132236 0,09335362 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,04132236 0,09326604 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,04132236 0,09317863 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,04132236 0,09309139 ! protein prenylation GO:0018342 18 7 0,000 0,04132236 0,09300431 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,04132236 0,09291739 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,04132236 0,09283063 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,04132236 0,09274403 ! activation of phospholipase C activity GO:0007202 103 54 1,000 0,04191939 0,09399631 GO:0010863|positive regulation of phospholipase C activity, ! negative regulation of cytoskeleton organization GO:0051494 124 54 1,000 0,04191939 0,09390879 ! positive regulation of caspase activity GO:0043280 95 55 1,000 0,04333321 0,09698576 GO:0010952|positive regulation of peptidase activity, ! positive regulation of phospholipase activity GO:0010518 104 55 1,000 0,04333321 0,09689563 ! heart morphogenesis GO:0003007 97 55 1,000 0,04333321 0,09680566 ! regulation of multicellular organism growth GO:0040014 85 55 1,000 0,04333321 0,09671586 ! nuclear export GO:0051168 97 55 1,000 0,04333321 0,09662623 ! skeletal muscle fiber development GO:0048741 111 56 1,000 0,04476464 0,09972566 ! positive regulation of organelle organization GO:0010638 100 56 1,000 0,04476464 0,09963341 ! regulation of bone remodeling GO:0046850 137 57 1,000 0,04621341 0,10276292 ! muscle fiber development GO:0048747 112 57 1,000 0,04621341 0,10266803 ! lipid modification GO:0030258 97 57 1,000 0,04621341 0,10257332 ! regulation of phospholipase activity GO:0010517 106 57 1,000 0,04621341 0,10247878 ! maintenance of location GO:0051235 118 57 1,000 0,04621341 0,10238441 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,04708525 0,10421998 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,04708525 0,10412419 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 0,000 0,04708525 0,10402858 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,04708525 0,10393314 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,04708525 0,10383787 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,04708525 0,10374278 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,04708525 0,10364787 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,04708525 0,10355313 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,04708525 0,10345856 ! meiotic prophase I GO:0007128 13 8 0,000 0,04708525 0,10336416 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,04708525 0,10326994 ! oligopeptide transport GO:0006857 15 8 0,000 0,04708525 0,10317588 ! UTP metabolic process GO:0046051 8 8 0,000 0,04708525 0,103082 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,04708525 0,10298829 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,04708525 0,10289475 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,04708525 0,10280138 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,04708525 0,10270818 ! succinate metabolic process GO:0006105 14 8 0,000 0,04708525 0,10261514 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,04708525 0,10252228 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,04708525 0,10242958 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,04708525 0,10233705 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,04708525 0,10224469 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,04708525 0,1021525 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,04708525 0,10206047 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,04708525 0,1019686 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,04708525 0,10187691 ! reflex GO:0060004 16 8 0,000 0,04708525 0,10178537 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,04708525 0,101694 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,04708525 0,1016028 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,04708525 0,10151176 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,04708525 0,10142088 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,04708525 0,10133016 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,04708525 0,10123961 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,04708525 0,10114921 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,04708525 0,10105898 ! astrocyte differentiation GO:0048708 18 8 0,000 0,04708525 0,10096891 ! histidine metabolic process GO:0006547 16 8 0,000 0,04708525 0,100879 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,04708525 0,10078925 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,04708525 0,10069966 ! glycine catabolic process GO:0006546 13 8 0,000 0,04708525 0,10061023 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,04708525 0,10052096 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,04708525 0,10043184 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,04708525 0,10034289 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,04708525 0,10025409 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,04708525 0,10016545 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,04708525 0,10007696 ! macrophage activation GO:0042116 12 8 0,000 0,04708525 0,09998863 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,04708525 0,09990046 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,04708525 0,09981244 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,04708525 0,09972458 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,04708525 0,09963687 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,04708525 0,09954931 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,04708525 0,09946191 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,04708525 0,09937467 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,04708525 0,09928757 ! osteoblast development GO:0002076 16 8 0,000 0,04708525 0,09920063 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,04708525 0,09911384 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,04708525 0,0990272 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,04708525 0,09894072 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,04708525 0,09885438 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,04708525 0,09876819 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,04708525 0,09868216 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,04708525 0,09859627 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,04708525 0,09851054 ! intermediate filament organization GO:0045109 12 8 0,000 0,04708525 0,09842495 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,04708525 0,09833951 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,04708525 0,09825422 ! cellular extravasation GO:0045123 12 8 0,000 0,04708525 0,09816908 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,04708525 0,09808409 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,04708525 0,09799924 ! response to antibiotic GO:0046677 11 8 0,000 0,04708525 0,09791454 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,04708525 0,09782998 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,04708525 0,09774557 ! DNA topological change GO:0006265 12 8 0,000 0,04708525 0,09766131 ! response to tropane GO:0014073 15 8 0,000 0,04708525 0,09757719 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,04708525 0,09749322 ! melanosome transport GO:0032402 13 8 0,000 0,04708525 0,09740939 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,04708525 0,0973257 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,04708525 0,09724216 ! mast cell activation GO:0045576 14 8 0,000 0,04708525 0,09715876 ! multicellular organismal aging GO:0010259 18 8 0,000 0,04708525 0,09707551 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,04708525 0,0969924 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,04708525 0,09690943 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,04708525 0,0968266 ! nucleosome disassembly GO:0006337 14 8 0,000 0,04708525 0,09674391 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,04708525 0,09666136 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,04708525 0,09657896 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,04708525 0,09649669 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,04708525 0,09641457 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,04708525 0,09633258 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,04708525 0,09625074 ! intracellular lipid transport GO:0032365 13 8 0,000 0,04708525 0,09616903 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,04708525 0,09608746 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,04708525 0,09600603 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,04708525 0,09592474 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,04708525 0,09584359 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,04708525 0,09576257 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,04708525 0,09568169 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,04708525 0,09560094 ! hormone catabolic process GO:0042447 17 8 0,000 0,04708525 0,09552034 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,04708525 0,09543986 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,04708525 0,09535953 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,04708525 0,09527933 ! ATP catabolic process GO:0006200 11 8 0,000 0,04708525 0,09519926 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,04708525 0,09511933 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,04708525 0,09503953 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,04708525 0,09495986 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,04708525 0,09488033 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,04708525 0,09480094 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,04708525 0,09472167 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,04708525 0,09464254 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,04708525 0,09456354 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,04708525 0,09448467 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,04708525 0,09440593 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,04708525 0,09432733 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,04708525 0,09424885 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,04708525 0,09417051 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,04708525 0,09409229 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,04708525 0,09401421 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,04708525 0,09393625 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,04708525 0,09385842 ! regulation of tissue remodeling GO:0034103 140 58 1,000 0,04767928 0,09496387 ! positive regulation of lipase activity GO:0060193 108 58 1,000 0,04767928 0,09488532 ! skeletal system morphogenesis GO:0048705 105 59 1,000 0,04916198 0,09775515 ! establishment of organelle localization GO:0051656 109 59 1,000 0,04916198 0,09767443 ! camera-type eye development GO:0043010 116 60 1,000 0,05066127 0,10057014 ! axon extension GO:0048675 15 9 0,000 0,05281369 0,10475659 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,05281369 0,1046703 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,05281369 0,10458415 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,05281369 0,10449814 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,05281369 0,10441228 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,05281369 0,10432655 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,05281369 0,10424097 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,05281369 0,10415553 ! phosphate transport GO:0006817 19 9 0,000 0,05281369 0,10407022 ! reproductive behavior GO:0019098 19 9 0,000 0,05281369 0,10398506 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,05281369 0,10390004 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,05281369 0,10381515 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,05281369 0,1037304 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,05281369 0,10364579 ! GTP metabolic process GO:0046039 9 9 0,000 0,05281369 0,10356132 ! RNA methylation GO:0001510 15 9 0,000 0,05281369 0,10347699 ! elastic fiber assembly GO:0048251 15 9 0,000 0,05281369 0,10339279 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,05281369 0,10330873 ! artery development GO:0060840 24 9 0,000 0,05281369 0,10322481 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,05281369 0,10314103 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,05281369 0,10305737 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,05281369 0,10297386 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,05281369 0,10289048 ! chemosensory behavior GO:0007635 20 9 0,000 0,05281369 0,10280724 ! microtubule bundle formation GO:0001578 21 9 0,000 0,05281369 0,10272413 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,05281369 0,10264115 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,05281369 0,10255831 ! leukocyte degranulation GO:0043299 16 9 0,000 0,05281369 0,1024756 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,05281369 0,10239302 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,05281369 0,10231058 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,05281369 0,10222827 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,05281369 0,1021461 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,05281369 0,10206405 ! protein targeting to ER GO:0045047 22 9 0,000 0,05281369 0,10198214 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,05281369 0,10190036 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,05281369 0,1018187 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,05281369 0,10173718 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,05281369 0,10165579 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,05281369 0,10157453 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,05281369 0,10149341 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,05281369 0,1014124 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,05281369 0,10133153 ! mannose metabolic process GO:0006013 13 9 0,000 0,05281369 0,10125079 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,05281369 0,10117018 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,05281369 0,10108969 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,05281369 0,10100933 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,05281369 0,1009291 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,05281369 0,100849 ! ruffle organization GO:0031529 15 9 0,000 0,05281369 0,10076903 ! retinol metabolic process GO:0042572 18 9 0,000 0,05281369 0,10068918 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,05281369 0,10060946 ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,05281369 0,10052986 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,05281369 0,10045039 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,05281369 0,10037105 GO:0030204|chondroitin sulfate metabolic process, ! oligodendrocyte development GO:0014003 10 9 0,000 0,05281369 0,10029183 ! segment specification GO:0007379 13 9 0,000 0,05281369 0,10021273 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,05281369 0,10013376 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,05281369 0,10005492 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,05281369 0,09997619 ! response to amine stimulus GO:0014075 13 9 0,000 0,05281369 0,0998976 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,05281369 0,09981912 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,05281369 0,09974077 ! erythrocyte development GO:0048821 15 9 0,000 0,05281369 0,09966254 ! gas homeostasis GO:0033483 16 9 0,000 0,05281369 0,09958444 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,05281369 0,09950646 ! renal water homeostasis GO:0003091 14 9 0,000 0,05281369 0,09942859 ! postreplication repair GO:0006301 22 9 0,000 0,05281369 0,09935085 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,05281369 0,09927324 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,05281369 0,09919574 ! icosanoid secretion GO:0032309 15 9 0,000 0,05281369 0,09911836 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,05281369 0,09904111 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,05281369 0,09896397 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,05281369 0,09888696 ! regulation of cell division GO:0051302 15 9 0,000 0,05281369 0,09881006 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,05281369 0,09873329 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,05281369 0,09865663 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,05281369 0,0985801 ! sterol catabolic process GO:0016127 11 9 0,000 0,05281369 0,09850368 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,05281369 0,09842738 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,05281369 0,09835119 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,05281369 0,09827513 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,05281369 0,09819918 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,05281369 0,09812335 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,05281369 0,09804764 ! musculoskeletal movement GO:0050881 14 9 0,000 0,05281369 0,09797205 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,05281369 0,09789657 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,05281369 0,0978212 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,05281369 0,09774596 ! purine base metabolic process GO:0006144 21 9 0,000 0,05281369 0,09767082 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,05281369 0,09759581 ! pigment granule transport GO:0051904 17 9 0,000 0,05281369 0,09752091 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,05281369 0,09744612 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,05281369 0,09737145 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,05281369 0,09729689 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,05281369 0,09722245 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,05281369 0,09714812 ! mitochondrion localization GO:0051646 15 9 0,000 0,05281369 0,09707391 ! viral reproductive process GO:0022415 126 62 1,000 0,05370858 0,09864339 ! water-soluble vitamin metabolic process GO:0006767 95 62 1,000 0,05370858 0,09856815 ! regulation of homeostatic process GO:0032844 134 62 1,000 0,05370858 0,09849302 ! ear development GO:0043583 103 62 1,000 0,05370858 0,09841801 ! regulation of mitosis GO:0007088 105 63 1,000 0,05525612 0,10117672 GO:0051783|regulation of nuclear division, ! steroid hormone receptor signaling pathway GO:0030518 129 63 1,000 0,05525612 0,10109978 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 1,000 0,05681925 0,10388078 ! multicellular organism reproduction GO:0032504 111 64 1,000 0,05681925 0,1038019 GO:0048609|reproductive process in a multicellular organism, ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,05850788 0,10680574 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,05850788 0,10672477 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,05850788 0,10664392 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,05850788 0,10656319 ! synapsis GO:0007129 13 10 0,000 0,05850788 0,10648258 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,05850788 0,10640209 ! N-glycan processing GO:0006491 20 10 0,000 0,05850788 0,10632173 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,05850788 0,10624149 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,05850788 0,10616136 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,05850788 0,10608136 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 0,05850788 0,10600148 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,05850788 0,10592172 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,05850788 0,10584208 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,05850788 0,10576256 ! androgen metabolic process GO:0008209 17 10 0,000 0,05850788 0,10568316 ! phospholipid efflux GO:0033700 16 10 0,000 0,05850788 0,10560388 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,05850788 0,10552471 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,05850788 0,10544567 ! lung alveolus development GO:0048286 26 10 0,000 0,05850788 0,10536674 ! pathogenesis GO:0009405 13 10 0,000 0,05850788 0,10528793 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,05850788 0,10520924 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,05850788 0,10513067 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,05850788 0,10505222 ! endoderm development GO:0007492 16 10 0,000 0,05850788 0,10497388 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,05850788 0,10489565 ! arginine catabolic process GO:0006527 13 10 0,000 0,05850788 0,10481755 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,05850788 0,10473956 ! proline metabolic process GO:0006560 13 10 0,000 0,05850788 0,10466169 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,05850788 0,10458393 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,05850788 0,10450629 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,05850788 0,10442876 ! V(D)J recombination GO:0033151 28 10 0,000 0,05850788 0,10435135 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,05850788 0,10427405 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,05850788 0,10419687 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,05850788 0,1041198 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,05850788 0,10404284 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,05850788 0,103966 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,05850788 0,10388928 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,05850788 0,10381266 ! epithelial cell development GO:0002064 20 10 0,000 0,05850788 0,10373616 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,05850788 0,10365977 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,05850788 0,10358349 ! macroautophagy GO:0016236 17 10 0,000 0,05850788 0,10350733 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,05850788 0,10343128 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,05850788 0,10335534 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,05850788 0,10327951 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,05850788 0,10320379 ! copper ion homeostasis GO:0055070 13 10 0,000 0,05850788 0,10312818 ! regulation of bone resorption GO:0045124 25 10 0,000 0,05850788 0,10305269 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,05850788 0,1029773 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,05850788 0,10290202 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,05850788 0,10282686 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,05850788 0,1027518 ! blastoderm segmentation GO:0007350 18 10 0,000 0,05850788 0,10267685 ! response to dsRNA GO:0043331 20 10 0,000 0,05850788 0,10260202 ! DNA ligation GO:0006266 19 10 0,000 0,05850788 0,10252729 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,05850788 0,10245267 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,05850788 0,10237816 ! melanosome localization GO:0032400 16 10 0,000 0,05850788 0,10230376 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,05850788 0,10222946 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,05850788 0,10215527 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,05850788 0,1020812 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,05850788 0,10200722 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,05850788 0,10193336 ! mRNA cleavage GO:0006379 17 10 0,000 0,05850788 0,1018596 ! protein sumoylation GO:0016925 15 10 0,000 0,05850788 0,10178595 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,05850788 0,1017124 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,05850788 0,10163897 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,05850788 0,10156563 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,05850788 0,10149241 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,05850788 0,10141929 ! salivary gland development GO:0007431 27 10 0,000 0,05850788 0,10134627 ! prophase GO:0051324 15 10 0,000 0,05850788 0,10127336 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,05850788 0,10120055 ! apical protein localization GO:0045176 15 10 0,000 0,05850788 0,10112785 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,05850788 0,10105525 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,05850788 0,10098276 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,05850788 0,10091037 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,05850788 0,10083809 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,05850788 0,1007659 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,05850788 0,10069383 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,05850788 0,10062185 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,05850788 0,10054998 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,05850788 0,10047821 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,05850788 0,10040654 ! detection of calcium ion GO:0005513 23 10 0,000 0,05850788 0,10033497 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,05850788 0,10026351 ! blastocyst formation GO:0001825 17 10 0,000 0,05850788 0,10019215 ! cerebellar cortex development GO:0021695 15 10 0,000 0,05850788 0,10012089 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,05850788 0,10004973 ! activation of innate immune response GO:0002218 12 10 0,000 0,05850788 0,09997867 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,05850788 0,09990771 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,05850788 0,09983686 ! establishment of cell polarity GO:0030010 16 10 0,000 0,05850788 0,0997661 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,05850788 0,09969544 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,05850788 0,09962489 ! localization within membrane GO:0051668 20 10 0,000 0,05850788 0,09955443 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 1,000 0,05999133 0,10200646 ! extracellular matrix organization GO:0030198 133 66 1,000 0,05999133 0,10193442 ! developmental maturation GO:0021700 116 66 1,000 0,05999133 0,10186248 ! cell projection assembly GO:0030031 120 66 1,000 0,05999133 0,10179065 ! activation of MAPK activity GO:0000187 115 67 1,000 0,06159981 0,10444619 ! lung development GO:0030324 144 67 1,000 0,06159981 0,10437263 ! homeostasis of number of cells GO:0048872 114 67 1,000 0,06159981 0,10429918 ! adaptive immune response GO:0002250 119 67 1,000 0,06159981 0,10422583 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 1,000 0,06322293 0,10689696 ! viral reproduction GO:0016032 134 68 1,000 0,06322293 0,10682189 ! regulation of lipase activity GO:0060191 130 68 1,000 0,06322293 0,10674693 ! respiratory burst GO:0045730 17 11 0,000 0,06416803 0,10826668 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,06416803 0,10819081 ! neuron fate specification GO:0048665 17 11 0,000 0,06416803 0,10811504 ! telencephalon cell migration GO:0022029 20 11 0,000 0,06416803 0,10803939 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,06416803 0,10796384 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,06416803 0,10788839 ! thyroid gland development GO:0030878 26 11 0,000 0,06416803 0,10781305 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 0,000 0,06416803 0,10773781 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,06416803 0,10766268 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,06416803 0,10758765 ! response to pain GO:0048265 24 11 0,000 0,06416803 0,10751273 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,06416803 0,10743792 ! T cell proliferation GO:0042098 26 11 0,000 0,06416803 0,1073632 ! blood vessel remodeling GO:0001974 29 11 0,000 0,06416803 0,10728859 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,06416803 0,10721409 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,06416803 0,10713968 ! bone resorption GO:0045453 16 11 0,000 0,06416803 0,10706538 ! ventral spinal cord development GO:0021517 21 11 0,000 0,06416803 0,10699119 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,06416803 0,10691709 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,06416803 0,1068431 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,06416803 0,10676921 ! melanocyte differentiation GO:0030318 21 11 0,000 0,06416803 0,10669543 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,06416803 0,10662174 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,06416803 0,10654816 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,06416803 0,10647468 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,06416803 0,1064013 GO:0043088|regulation of Cdc42 GTPase activity, ! lipid digestion GO:0044241 18 11 0,000 0,06416803 0,10632802 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,06416803 0,10625484 ! UV protection GO:0009650 19 11 0,000 0,06416803 0,10618176 ! adult heart development GO:0007512 14 11 0,000 0,06416803 0,10610879 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,06416803 0,10603591 ! temperature homeostasis GO:0001659 17 11 0,000 0,06416803 0,10596313 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,06416803 0,10589046 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,06416803 0,10581788 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,06416803 0,1057454 ! regulation of organ growth GO:0046620 13 11 0,000 0,06416803 0,10567302 ! pigment granule localization GO:0051875 20 11 0,000 0,06416803 0,10560074 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,06416803 0,10552856 ! vasoconstriction GO:0042310 18 11 0,000 0,06416803 0,10545648 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,06416803 0,10538449 ! embryonic axis specification GO:0000578 18 11 0,000 0,06416803 0,10531261 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,06416803 0,10524082 ! snRNA metabolic process GO:0016073 24 11 0,000 0,06416803 0,10516913 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,06416803 0,10509754 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,06416803 0,10502604 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,06416803 0,10495465 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,06416803 0,10488335 ! zymogen activation GO:0031638 15 11 0,000 0,06416803 0,10481214 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,06416803 0,10474103 ! neuroblast proliferation GO:0007405 24 11 0,000 0,06416803 0,10467002 ! nucleosome positioning GO:0016584 15 11 0,000 0,06416803 0,10459911 ! regulation of isotype switching GO:0045191 22 11 0,000 0,06416803 0,10452829 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,06416803 0,10445757 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,06416803 0,10438694 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,06416803 0,10431641 ! acid secretion GO:0046717 18 11 0,000 0,06416803 0,10424597 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,06416803 0,10417563 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,06416803 0,10410538 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,06416803 0,10403523 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,06416803 0,10396517 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,06416803 0,10389521 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! cholesterol efflux GO:0033344 19 11 0,000 0,06416803 0,10382534 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,06416803 0,10375557 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,06416803 0,10368589 ! germ cell migration GO:0008354 25 11 0,000 0,06416803 0,1036163 ! embryonic gut development GO:0048566 15 11 0,000 0,06416803 0,1035468 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,06416803 0,1034774 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,06416803 0,10340809 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,06416803 0,10333888 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,06416803 0,10326976 ! defense response to fungus GO:0050832 13 11 0,000 0,06416803 0,10320072 ! developmental induction GO:0031128 19 11 0,000 0,06416803 0,10313179 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,06416803 0,10306294 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,06416803 0,10299419 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,06416803 0,10292552 ! sequestering of metal ion GO:0051238 14 11 0,000 0,06416803 0,10285695 ! lamellipodium assembly GO:0030032 20 11 0,000 0,06416803 0,10278847 ! nucleus localization GO:0051647 19 11 0,000 0,06416803 0,10272008 ! regulation of synapse organization GO:0050807 17 11 0,000 0,06416803 0,10265178 ! cAMP-mediated signaling GO:0019933 120 69 1,000 0,06486046 0,10369055 ! respiratory tube development GO:0030323 150 70 1,000 0,06651218 0,1062605 ! humoral immune response GO:0006959 109 71 1,000 0,06817786 0,10884932 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,06979434 0,11135622 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,06979434 0,11128242 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,06979434 0,11120873 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,06979434 0,11113513 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,06979434 0,11106163 ! cartilage condensation GO:0001502 20 12 0,000 0,06979434 0,11098822 ! mating GO:0007618 17 12 0,000 0,06979434 0,11091491 ! protein complex disassembly GO:0043241 27 12 0,000 0,06979434 0,1108417 GO:0043624|cellular protein complex disassembly, ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,06979434 0,11076859 ! hippocampus development GO:0021766 26 12 0,000 0,06979434 0,11069557 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,06979434 0,11062265 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,06979434 0,11054982 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,06979434 0,11047709 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,06979434 0,11040446 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,06979434 0,11033192 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,06979434 0,11025947 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,06979434 0,11018712 ! drug transport GO:0015893 16 12 0,000 0,06979434 0,11011487 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,06979434 0,11004271 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,06979434 0,10997065 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,06979434 0,10989868 ! polyamine metabolic process GO:0006595 17 12 0,000 0,06979434 0,1098268 ! mitotic spindle organization GO:0007052 21 12 0,000 0,06979434 0,10975502 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,06979434 0,10968333 ! forebrain cell migration GO:0021885 21 12 0,000 0,06979434 0,10961173 ! asymmetric protein localization GO:0008105 20 12 0,000 0,06979434 0,10954023 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,06979434 0,10946883 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,06979434 0,10939751 ! entry into host cell GO:0030260 32 12 0,000 0,06979434 0,10932629 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! monoamine transport GO:0015844 18 12 0,000 0,06979434 0,10925516 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,06979434 0,10918412 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,06979434 0,10911318 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,06979434 0,10904232 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,06979434 0,10897156 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,06979434 0,10890089 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,06979434 0,10883032 ! protein homotetramerization GO:0051289 21 12 0,000 0,06979434 0,10875983 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,06979434 0,10868944 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,06979434 0,10861913 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,06979434 0,10854892 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,06979434 0,1084788 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,06979434 0,10840877 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,06979434 0,10833882 ! fucose catabolic process GO:0019317 22 12 0,000 0,06979434 0,10826897 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,06979434 0,10819921 ! histone methylation GO:0016571 26 12 0,000 0,06979434 0,10812954 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,06979434 0,10805996 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,06979434 0,10799047 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,06979434 0,10792107 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,06979434 0,10785175 ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,06979434 0,10778253 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,06979434 0,10771339 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,06979434 0,10764434 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,06979434 0,10757539 ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,06979434 0,10750652 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,06979434 0,10743773 ! response to cold GO:0009409 17 12 0,000 0,06979434 0,10736904 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,06979434 0,10730043 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,06979434 0,10723191 ! regulation of caspase activity GO:0043281 122 72 1,000 0,06985726 0,10726009 ! phosphoinositide metabolic process GO:0030384 128 72 1,000 0,06985726 0,10719169 ! carbohydrate transport GO:0008643 110 72 1,000 0,06985726 0,10712337 ! respiratory system development GO:0060541 153 72 1,000 0,06985726 0,10705514 ! axon guidance GO:0007411 139 73 1,000 0,07155017 0,1095797 ! regulation of endopeptidase activity GO:0052548 125 74 1,000 0,07325637 0,11212139 ! organelle localization GO:0051640 136 74 1,000 0,07325637 0,11205011 ! rhythmic process GO:0048511 128 75 1,000 0,07497563 0,11460697 ! cGMP metabolic process GO:0046068 18 13 0,000 0,075387 0,11516262 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,075387 0,11508955 ! regulation of chemokine production GO:0032642 18 13 0,000 0,075387 0,11501657 ! peroxisomal transport GO:0043574 24 13 0,000 0,075387 0,11494368 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,075387 0,11487089 ! lipid localization GO:0010876 28 13 0,000 0,075387 0,11479819 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,075387 0,11472557 ! organelle fusion GO:0048284 32 13 0,000 0,075387 0,11465306 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,075387 0,11458063 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,075387 0,11450829 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,075387 0,11443605 ! endocrine pancreas development GO:0031018 22 13 0,000 0,075387 0,11436389 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,075387 0,11429183 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,075387 0,11421986 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,075387 0,11414798 ! methionine metabolic process GO:0006555 27 13 0,000 0,075387 0,11407618 ! plasma membrane organization GO:0007009 24 13 0,000 0,075387 0,11400448 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,075387 0,11393287 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,075387 0,11386135 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,075387 0,11378992 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,075387 0,11371858 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,075387 0,11364733 ! cytokine metabolic process GO:0042107 22 13 0,000 0,075387 0,11357616 ! exocrine system development GO:0035272 32 13 0,000 0,075387 0,11350509 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,075387 0,1134341 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,075387 0,11336321 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,075387 0,1132924 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,075387 0,11322168 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,075387 0,11315105 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,075387 0,11308051 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,075387 0,11301005 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,075387 0,11293968 ! ribosome assembly GO:0042255 17 13 0,000 0,075387 0,1128694 ! regulation of monooxygenase activity GO:0032768 33 13 0,000 0,075387 0,11279921 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,075387 0,11272911 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,075387 0,11265909 ! chromatin silencing GO:0006342 26 13 0,000 0,075387 0,11258916 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,075387 0,11251931 ! regulation of epidermis development GO:0045682 19 13 0,000 0,075387 0,11244956 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,075387 0,11237988 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,075387 0,1123103 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,075387 0,1122408 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,075387 0,11217139 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,075387 0,11210206 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,075387 0,11203282 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,075387 0,11196366 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,075387 0,11189459 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,075387 0,11182561 ! embryonic placenta development GO:0001892 23 13 0,000 0,075387 0,11175671 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,075387 0,11168789 ! insulin secretion GO:0030073 23 13 0,000 0,075387 0,11161916 ! actin filament polymerization GO:0030041 24 13 0,000 0,075387 0,11155051 ! acrosome reaction GO:0007340 18 13 0,000 0,075387 0,11148195 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 0,0784525 0,11594393 ! rRNA transcription GO:0009303 25 14 0,000 0,08094623 0,11955594 ! lactation GO:0007595 26 14 0,000 0,08094623 0,1194826 ! reproductive cellular process GO:0048610 20 14 0,000 0,08094623 0,11940934 ! tRNA modification GO:0006400 20 14 0,000 0,08094623 0,11933617 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,08094623 0,11926309 ! water transport GO:0006833 21 14 0,000 0,08094623 0,11919011 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,08094623 0,11911721 ! non-recombinational repair GO:0000726 25 14 0,000 0,08094623 0,1190444 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,08094623 0,11897168 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,08094623 0,11889904 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,08094623 0,1188265 ! RNA polyadenylation GO:0043631 30 14 0,000 0,08094623 0,11875404 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,08094623 0,11868168 ! palate development GO:0060021 31 14 0,000 0,08094623 0,1186094 ! regulated secretory pathway GO:0045055 23 14 0,000 0,08094623 0,11853721 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,08094623 0,1184651 ! arginine metabolic process GO:0006525 17 14 0,000 0,08094623 0,11839309 ! regulation of heart rate GO:0002027 24 14 0,000 0,08094623 0,11832116 ! organic alcohol transport GO:0015850 29 14 0,000 0,08094623 0,11824932 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,08094623 0,11817757 ! embryo implantation GO:0007566 30 14 0,000 0,08094623 0,1181059 ! neutral amino acid transport GO:0015804 26 14 0,000 0,08094623 0,11803432 ! L-amino acid transport GO:0015807 30 14 0,000 0,08094623 0,11796283 ! bone mineralization GO:0030282 17 14 0,000 0,08094623 0,11789142 ! stem cell development GO:0048864 43 14 0,000 0,08094623 0,1178201 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,08094623 0,11774887 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,08094623 0,11767772 ! cerebellum development GO:0021549 21 14 0,000 0,08094623 0,11760666 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,08094623 0,11753569 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,08094623 0,1174648 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,08094623 0,11739399 ! cofactor transport GO:0051181 26 14 0,000 0,08094623 0,11732327 ! NADP metabolic process GO:0006739 24 14 0,000 0,08094623 0,11725264 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,08094623 0,11718209 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,08094623 0,11711162 ! intestinal absorption GO:0050892 25 14 0,000 0,08094623 0,11704125 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,08094623 0,11697095 ! oxygen transport GO:0015671 21 14 0,000 0,08094623 0,11690074 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,08094623 0,11683061 ! male genitalia development GO:0030539 24 14 0,000 0,08094623 0,11676057 ! regulation of RNA stability GO:0043487 32 14 0,000 0,08094623 0,11669061 ! regulation of axon extension GO:0030516 37 14 0,000 0,08094623 0,11662074 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,08094623 0,11655095 ! activation of protein kinase activity GO:0032147 147 79 1,000 0,08197906 0,11796748 ! regulation of peptidase activity GO:0052547 134 79 1,000 0,08197906 0,11789697 ! regulation of synaptic transmission GO:0050804 134 79 1,000 0,08197906 0,11782654 ! regulation of adenylate cyclase activity GO:0045761 156 80 1,000 0,08376046 0,12031502 ! response to metal ion GO:0010038 140 80 1,000 0,08376046 0,12024324 ! regulation of neuron differentiation GO:0045664 167 81 1,000 0,08555365 0,12274424 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,08647222 0,12398817 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,08647222 0,12391433 ! superoxide anion generation GO:0042554 20 15 0,000 0,08647222 0,12384057 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,08647222 0,1237669 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,08647222 0,12369331 ! copper ion transport GO:0006825 20 15 0,000 0,08647222 0,12361982 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,08647222 0,12354641 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,08647222 0,12347309 ! sulfate transport GO:0008272 23 15 0,000 0,08647222 0,12339985 ! response to cAMP GO:0051591 22 15 0,000 0,08647222 0,12332671 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,08647222 0,12325364 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,08647222 0,12318067 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,08647222 0,12310778 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,08647222 0,12303498 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,08647222 0,12296227 ! response to hexose stimulus GO:0009746 22 15 0,000 0,08647222 0,12288964 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,08647222 0,12281709 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,08647222 0,12274463 ! pituitary gland development GO:0021983 29 15 0,000 0,08647222 0,12267226 ! vesicle coating GO:0006901 33 15 0,000 0,08647222 0,12259997 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,08647222 0,12252777 ! regulation of exocytosis GO:0017157 22 15 0,000 0,08647222 0,12245565 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,08647222 0,12238362 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,08647222 0,12231167 ! regulation of vasodilation GO:0042312 26 15 0,000 0,08647222 0,12223981 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,08647222 0,12216803 ! histone deacetylation GO:0016575 20 15 0,000 0,08647222 0,12209633 ! mRNA splice site selection GO:0006376 38 15 0,000 0,08647222 0,12202472 ! tissue regeneration GO:0042246 26 15 0,000 0,08647222 0,1219532 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,08647222 0,12188175 ! water homeostasis GO:0030104 27 15 0,000 0,08647222 0,12181039 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,08647222 0,12173912 ! muscle maintenance GO:0046716 26 15 0,000 0,08647222 0,12166793 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,08647222 0,12159682 ! dopamine metabolic process GO:0042417 35 15 0,000 0,08647222 0,12152579 ! heme biosynthetic process GO:0006783 29 15 0,000 0,08647222 0,12145485 ! cell killing GO:0001906 29 15 0,000 0,08647222 0,12138399 ! detection of bacterium GO:0016045 18 15 0,000 0,08647222 0,12131321 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,08647222 0,12124251 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,08647222 0,1211719 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,08647222 0,12110137 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,08647222 0,12103092 ! peptide hormone processing GO:0016486 23 15 0,000 0,08647222 0,12096055 ! regulation of cAMP biosynthetic process GO:0030817 161 82 1,000 0,08735844 0,12212923 ! regulation of cyclase activity GO:0031279 159 82 1,000 0,08735844 0,12205831 ! regulation of lyase activity GO:0051339 160 83 1,000 0,08917462 0,12452359 ! regulation of cAMP metabolic process GO:0030814 168 84 1,000 0,091002 0,12700163 ! regulation of transmission of nerve impulse GO:0051969 141 84 1,000 0,091002 0,126928 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,09196516 0,12819709 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,09196516 0,12812285 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,09196516 0,12804871 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,09196516 0,12797465 ! bone remodeling GO:0046849 27 16 0,000 0,09196516 0,12790068 ! filopodium assembly GO:0046847 32 16 0,000 0,09196516 0,12782679 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,09196516 0,12775298 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,09196516 0,12767927 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,09196516 0,12760563 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,09196516 0,12753209 ! startle response GO:0001964 28 16 0,000 0,09196516 0,12745862 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,09196516 0,12738524 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,09196516 0,12731195 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,09196516 0,12723874 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,09196516 0,12716561 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,09196516 0,12709257 ! protein polyubiquitination GO:0000209 34 16 0,000 0,09196516 0,12701962 ! glutamate metabolic process GO:0006536 22 16 0,000 0,09196516 0,12694674 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,09196516 0,12687395 ! response to osmotic stress GO:0006970 25 16 0,000 0,09196516 0,12680124 ! lysosomal transport GO:0007041 26 16 0,000 0,09196516 0,12672862 ! fructose metabolic process GO:0006000 25 16 0,000 0,09196516 0,12665608 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,09196516 0,12658362 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,09196516 0,12651125 ! negative regulation of immune response GO:0050777 35 16 0,000 0,09196516 0,12643895 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,09196516 0,12636674 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,09196516 0,12629462 ! DNA replication initiation GO:0006270 27 16 0,000 0,09196516 0,12622257 ! neuron recognition GO:0008038 35 16 0,000 0,09196516 0,12615061 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,09196516 0,12607873 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,09196516 0,12600693 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,09196516 0,12593521 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,09196516 0,12586358 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,09196516 0,12579202 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,09196516 0,12572055 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,09196516 0,12564916 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,09196516 0,12557785 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,09196516 0,12550662 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,09196516 0,12543547 ! positive regulation of cell activation GO:0050867 145 85 1,000 0,09284036 0,12655746 GO:0002696|positive regulation of leukocyte activation, ! response to inorganic substance GO:0010035 153 86 1,000 0,09468953 0,1290051 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 1,000 0,0965493 0,13146441 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! positive regulation of cell killing GO:0031343 32 17 0,000 0,09742525 0,1325821 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,09742525 0,13250716 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,09742525 0,13243229 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,09742525 0,13235751 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,09742525 0,13228282 ! endothelial cell migration GO:0043542 28 17 0,000 0,09742525 0,13220821 ! inositol metabolic process GO:0006020 28 17 0,000 0,09742525 0,13213369 ! gene silencing by RNA GO:0031047 36 17 0,000 0,09742525 0,13205924 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,09742525 0,13198489 ! glial cell development GO:0021782 27 17 0,000 0,09742525 0,13191061 ! limbic system development GO:0021761 36 17 0,000 0,09742525 0,13183642 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,09742525 0,13176231 ! adult walking behavior GO:0007628 33 17 0,000 0,09742525 0,13168829 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,09742525 0,13161435 ! heart looping GO:0001947 30 17 0,000 0,09742525 0,13154049 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,09742525 0,13146672 ! myoblast differentiation GO:0045445 45 17 0,000 0,09742525 0,13139303 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,09742525 0,13131942 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,09742525 0,13124589 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,09742525 0,13117244 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,09742525 0,13109908 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,09742525 0,1310258 ! glycine metabolic process GO:0006544 28 17 0,000 0,09742525 0,1309526 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,09742525 0,13087948 ! membrane budding GO:0006900 37 17 0,000 0,09742525 0,13080645 ! DNA integration GO:0015074 29 17 0,000 0,09742525 0,1307335 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,09742525 0,13066062 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,09742525 0,13058783 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,09742525 0,13051512 ! genitalia development GO:0048806 30 17 0,000 0,09742525 0,13044249 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,09742525 0,13036994 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,09742525 0,13029747 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,09742525 0,13022509 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,09742525 0,13015278 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,09742525 0,13008055 ! steroid catabolic process GO:0006706 31 17 0,000 0,09742525 0,13000841 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,09742525 0,12993634 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,09742525 0,12986435 ! gas transport GO:0015669 25 17 0,000 0,09742525 0,12979245 ! organic cation transport GO:0015695 31 17 0,000 0,09742525 0,12972062 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,09742525 0,12964887 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,09742525 0,1295772 ! microspike assembly GO:0030035 36 17 0,000 0,09742525 0,12950561 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,09742525 0,1294341 ! cellular respiration GO:0045333 135 88 1,000 0,09841948 0,13068281 ! regulation of neurological system process GO:0031644 148 88 1,000 0,09841948 0,13061073 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 1,000 0,10219031 0,13554017 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,1028527 0,13634357 ! neuron maturation GO:0042551 42 18 0,000 0,1028527 0,13626849 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,1028527 0,1361935 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,1028527 0,13611858 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,1028527 0,13604375 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,1028527 0,135969 ! memory GO:0007613 31 18 0,000 0,1028527 0,13589434 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,1028527 0,13581975 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,1028527 0,13574525 ! patterning of blood vessels GO:0001569 39 18 0,000 0,1028527 0,13567083 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,1028527 0,13559648 GO:0042744|hydrogen peroxide catabolic process, ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,1028527 0,13552223 ! glutamine metabolic process GO:0006541 29 18 0,000 0,1028527 0,13544805 ! response to retinoic acid GO:0032526 26 18 0,000 0,1028527 0,13537395 ! response to fungus GO:0009620 21 18 0,000 0,1028527 0,13529994 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,1028527 0,135226 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,1028527 0,13515215 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,1028527 0,13507838 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,1028527 0,13500468 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,1028527 0,13493107 ! vitamin transport GO:0051180 27 18 0,000 0,1028527 0,13485754 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,1028527 0,13478409 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,1028527 0,13471072 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,1028527 0,13463742 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,1028527 0,13456421 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,1028527 0,13449108 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,1028527 0,13441803 ! response to protein stimulus GO:0051789 149 91 1,000 0,10409058 0,13596196 ! vitamin metabolic process GO:0006766 139 92 1,000 0,10600052 0,13838158 ! regulation of nucleotide metabolic process GO:0006140 182 93 1,000 0,10791993 0,14081093 ! carbohydrate biosynthetic process GO:0016051 141 93 1,000 0,10791993 0,14073461 ! negative regulation of multicellular organismal process GO:0051241 166 93 1,000 0,10791993 0,14065837 ! protein secretion GO:0009306 39 19 0,000 0,10824768 0,14100916 ! positive regulation of translation GO:0045727 30 19 0,000 0,10824768 0,14093286 ! negative regulation of defense response GO:0031348 25 19 0,000 0,10824768 0,14085664 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,10824768 0,1407805 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,10824768 0,14070444 ! skin development GO:0043588 36 19 0,000 0,10824768 0,14062847 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,10824768 0,14055257 ! bile acid metabolic process GO:0008206 29 19 0,000 0,10824768 0,14047676 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,10824768 0,14040103 ! cerebral cortex development GO:0021987 36 19 0,000 0,10824768 0,14032539 ! pigmentation during development GO:0048066 41 19 0,000 0,10824768 0,14024982 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,10824768 0,14017434 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,10824768 0,14009893 ! heme metabolic process GO:0042168 36 19 0,000 0,10824768 0,14002361 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,10824768 0,13994837 ! plasma membrane fusion GO:0045026 28 19 0,000 0,10824768 0,13987321 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,10824768 0,13979813 ! peptide cross-linking GO:0018149 37 19 0,000 0,10824768 0,13972313 ! protein export from nucleus GO:0006611 36 19 0,000 0,10824768 0,13964821 ! heart process GO:0003015 30 19 0,000 0,10824768 0,13957338 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,10824768 0,13949862 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,10824768 0,13942394 ! visual learning GO:0008542 36 19 0,000 0,10824768 0,13934934 ! G1 phase GO:0051318 40 19 0,000 0,10824768 0,13927482 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,10824768 0,13920038 ! cell-cell junction organization GO:0045216 35 19 0,000 0,10824768 0,13912603 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,10824768 0,13905175 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,10824768 0,13897755 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,10824768 0,13890342 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,10824768 0,13882938 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,10824768 0,13875542 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,10824768 0,13868153 ! cilium assembly GO:0042384 37 19 0,000 0,10824768 0,13860773 ! peptide hormone secretion GO:0030072 31 19 0,000 0,10824768 0,138534 ! female pregnancy GO:0007565 164 94 1,000 0,10984864 0,14050814 ! regulation of T cell activation GO:0050863 158 94 1,000 0,10984864 0,14043349 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,1136104 0,14516549 ! positive regulation of ossification GO:0045778 47 20 0,000 0,1136104 0,14508844 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,1136104 0,14501147 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,1136104 0,14493458 ! cAMP metabolic process GO:0046058 36 20 0,000 0,1136104 0,14485778 ! response to vitamin GO:0033273 31 20 0,000 0,1136104 0,14478105 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,1136104 0,14470441 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,1136104 0,14462784 ! retinoid metabolic process GO:0001523 32 20 0,000 0,1136104 0,14455136 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,1136104 0,14447496 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,1136104 0,14439864 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,1136104 0,1443224 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,1136104 0,14424624 GO:0032392|DNA geometric change, ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,1136104 0,14417016 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,1136104 0,14409416 ! body fluid secretion GO:0007589 31 20 0,000 0,1136104 0,14401824 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,1136104 0,1439424 ! peptide secretion GO:0002790 35 20 0,000 0,1136104 0,14386665 ! stem cell differentiation GO:0048863 53 20 0,000 0,1136104 0,14379097 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,1136104 0,14371537 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,1136104 0,14363985 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,1136104 0,1435644 ! sensory perception of pain GO:0019233 30 20 0,000 0,1136104 0,14348904 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,1136104 0,14341376 ! diencephalon development GO:0021536 34 20 0,000 0,1136104 0,14333856 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,1136104 0,14326343 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,1136104 0,14318838 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,1136104 0,14311342 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,1136104 0,14303853 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,1136104 0,14296372 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,1136104 0,14288898 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,1136104 0,14281433 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,1136104 0,14273975 ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,1136104 0,14266525 ! actin filament-based movement GO:0030048 43 20 0,000 0,1136104 0,14259083 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,1136104 0,14251649 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,1136104 0,14244222 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,1136104 0,14236803 ! protein ubiquitination GO:0016567 217 97 1,000 0,11568875 0,14489699 ! response to virus GO:0009615 160 98 1,000 0,11765286 0,14728032 ! regulation of cell killing GO:0031341 42 21 0,000 0,11894105 0,14881548 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,11894105 0,14873813 ! hormone secretion GO:0046879 38 21 0,000 0,11894105 0,14866087 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,11894105 0,14858368 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,11894105 0,14850657 ! axis specification GO:0009798 38 21 0,000 0,11894105 0,14842955 ! smooth muscle contraction GO:0006939 46 21 0,000 0,11894105 0,1483526 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,11894105 0,14827573 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,11894105 0,14819895 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,11894105 0,14812224 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,11894105 0,14804561 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,11894105 0,14796906 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,11894105 0,14789259 ! cytolysis GO:0019835 24 21 0,000 0,11894105 0,1478162 ! vasodilation GO:0042311 39 21 0,000 0,11894105 0,14773989 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,11894105 0,14766366 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,11894105 0,1475875 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,11894105 0,14751143 ! DNA modification GO:0006304 34 21 0,000 0,11894105 0,14743543 ! collagen fibril organization GO:0030199 59 21 0,000 0,11894105 0,14735951 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,11894105 0,14728367 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,11894105 0,1472079 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,11894105 0,14713222 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,11894105 0,14705661 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,11894105 0,14698108 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,11894105 0,14690563 ! sperm-egg recognition GO:0035036 21 21 0,000 0,11894105 0,14683025 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 1,000 0,11962539 0,14759932 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,12423982 0,15321425 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,12423982 0,15313576 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,12423982 0,15305735 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,12423982 0,15297902 GO:0034105|positive regulation of tissue remodeling, ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,12423982 0,15290077 ! keratinization GO:0031424 28 22 0,000 0,12423982 0,1528226 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,12423982 0,15274451 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,12423982 0,15266649 ! sensory perception of taste GO:0050909 28 22 0,000 0,12423982 0,15258856 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,12423982 0,15251071 ! vacuolar transport GO:0007034 36 22 0,000 0,12423982 0,15243294 ! lysosome organization GO:0007040 41 22 0,000 0,12423982 0,15235525 ! central nervous system neuron development GO:0021954 46 22 0,000 0,12423982 0,15227763 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,12423982 0,1522001 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,12423982 0,15212264 ! fucose metabolic process GO:0006004 39 22 0,000 0,12423982 0,15204527 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,12423982 0,15196797 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,12423982 0,15189075 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,12423982 0,15181361 GO:0060415|muscle tissue morphogenesis, ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,12423982 0,15173655 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,12423982 0,15165956 ! sarcomere organization GO:0045214 30 22 0,000 0,12423982 0,15158266 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,12423982 0,15150583 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,12423982 0,15142908 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,12423982 0,1513524 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,12950689 0,15768906 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,12950689 0,1576093 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,12950689 0,15752961 ! viral genome replication GO:0019079 41 23 0,000 0,12950689 0,15745001 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,12950689 0,15737049 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,12950689 0,15729105 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,12950689 0,15721169 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,12950689 0,15713241 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,12950689 0,15705321 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,12950689 0,15697409 ! visual behavior GO:0007632 42 23 0,000 0,12950689 0,15689505 ! regulation of DNA recombination GO:0000018 48 23 0,000 0,12950689 0,15681609 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,12950689 0,15673721 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! peroxisome organization GO:0007031 37 23 0,000 0,12950689 0,15665841 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,12950689 0,15657969 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,12950689 0,15650104 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,12950689 0,15642248 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,12950689 0,15634399 GO:0051693|actin filament capping, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,12950689 0,15626559 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,12950689 0,15618726 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,12950689 0,15610901 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,12950689 0,15603083 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,12950689 0,15595274 ! fatty acid transport GO:0015908 44 23 0,000 0,12950689 0,15587473 ! platelet activation GO:0030168 37 23 0,000 0,12950689 0,15579679 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,12950689 0,15571893 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,12950689 0,15564115 ! hormone transport GO:0009914 40 23 0,000 0,12950689 0,15556344 ! cell-cell recognition GO:0009988 25 23 0,000 0,12950689 0,15548582 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,12950689 0,15540827 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,12950689 0,1553308 ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,12950689 0,1552534 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,13474246 0,16144938 GO:0016444|somatic cell DNA recombination, ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,13474246 0,16136902 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,13474246 0,16128874 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,13474246 0,16120853 ! vesicle docking GO:0048278 47 24 0,000 0,13474246 0,16112841 ! spinal cord development GO:0021510 47 24 0,000 0,13474246 0,16104837 ! vacuole organization GO:0007033 43 24 0,000 0,13474246 0,1609684 ! digestive system process GO:0022600 39 24 0,000 0,13474246 0,16088852 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,13474246 0,16080871 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,13474246 0,16072898 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,13474246 0,16064934 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,13474246 0,16056977 ! membrane depolarization GO:0051899 39 24 0,000 0,13474246 0,16049028 ! pallium development GO:0021543 49 24 0,000 0,13474246 0,16041087 ! pentose metabolic process GO:0019321 35 24 0,000 0,13474246 0,16033153 ! regulation of oxidoreductase activity GO:0051341 46 24 0,000 0,13474246 0,16025228 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,13474246 0,1601731 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,13474246 0,160094 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,13474246 0,16001498 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,13474246 0,15993604 GO:0033013|tetrapyrrole metabolic process, ! regulation of multi-organism process GO:0043900 36 24 0,000 0,13474246 0,15985718 ! regulation of amine transport GO:0051952 40 24 0,000 0,13474246 0,15977839 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,13994671 0,16586788 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,13994671 0,16578621 ! phototransduction GO:0007602 33 25 0,000 0,13994671 0,16570462 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,13994671 0,16562312 GO:0006479|protein amino acid methylation, ! sperm motility GO:0030317 31 25 0,000 0,13994671 0,16554169 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,13994671 0,16546034 ! chromosome condensation GO:0030261 45 25 0,000 0,13994671 0,16537907 ! osteoblast differentiation GO:0001649 60 25 0,000 0,13994671 0,16529789 ! neural crest cell development GO:0014032 54 25 0,000 0,13994671 0,16521678 GO:0014033|neural crest cell differentiation, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,13994671 0,16513575 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,13994671 0,1650548 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,13994671 0,16497393 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,13994671 0,16489314 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,13994671 0,16481243 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! immunoglobulin production GO:0002377 55 25 0,000 0,13994671 0,1647318 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,13994671 0,16465124 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,13994671 0,16457077 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,13994671 0,16449037 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,13994671 0,16441006 ! telomere organization GO:0032200 43 25 0,000 0,13994671 0,16432982 GO:0000723|telomere maintenance, ! liver development GO:0001889 53 25 0,000 0,13994671 0,16424966 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,14511984 0,17023809 ! embryonic pattern specification GO:0009880 44 26 0,000 0,14511984 0,17015513 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,14511984 0,17007225 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,14511984 0,16998945 ! initiation of viral infection GO:0019059 57 26 0,000 0,14511984 0,16990673 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,14511984 0,16982409 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,14511984 0,16974153 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,14511984 0,16965905 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,14511984 0,16957665 ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,14511984 0,16949434 ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,14511984 0,1694121 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,14511984 0,16932994 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,14511984 0,16924786 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,14511984 0,16916586 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,14511984 0,16908394 ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,14511984 0,1690021 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,14511984 0,16892033 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,14511984 0,16883865 ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,14511984 0,16875705 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,14511984 0,16867552 ! neuron fate commitment GO:0048663 48 27 0,000 0,15026202 0,17456804 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,15026202 0,17448379 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,15026202 0,17439962 ! iron ion transport GO:0006826 59 27 0,000 0,15026202 0,17431553 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,15026202 0,17423152 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,15026202 0,1741476 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,15026202 0,17406375 ! fat cell differentiation GO:0045444 50 27 0,000 0,15026202 0,17397999 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,15026202 0,1738963 ! autophagy GO:0006914 41 27 0,000 0,15026202 0,1738127 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,15026202 0,17372917 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,15026202 0,17364573 ! glutathione metabolic process GO:0006749 39 27 0,000 0,15026202 0,17356237 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,15026202 0,17347908 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,15026202 0,17339588 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,15026202 0,17331276 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,15537344 0,17912242 ! circadian rhythm GO:0007623 50 28 0,000 0,15537344 0,17903663 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,15537344 0,17895093 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,15537344 0,1788653 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,15537344 0,17877976 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,15537344 0,1786943 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,15537344 0,17860893 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,15537344 0,17852363 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,15537344 0,17843842 ! synaptogenesis GO:0007416 42 28 0,000 0,15537344 0,17835329 ! lipid oxidation GO:0034440 43 28 0,000 0,15537344 0,17826823 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,15537344 0,17818326 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,15537344 0,17809837 ! translational initiation GO:0006413 65 29 0,000 0,16045428 0,18383476 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,16045428 0,18374726 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,16045428 0,18365984 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,16045428 0,18357251 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,16045428 0,18348526 ! catechol metabolic process GO:0009712 54 29 0,000 0,16045428 0,18339809 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,16045428 0,18331101 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,16045428 0,18322401 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,16045428 0,18313709 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,16045428 0,18305025 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,16045428 0,1829635 ! cell fate determination GO:0001709 60 29 0,000 0,16045428 0,18287683 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,16045428 0,18279024 ! detection of light stimulus GO:0009583 38 29 0,000 0,16045428 0,18270373 ! regulation of coagulation GO:0050818 46 29 0,000 0,16045428 0,18261731 ! phenol metabolic process GO:0018958 55 30 0,000 0,16550472 0,18827629 ! zinc ion transport GO:0006829 45 30 0,000 0,16550472 0,18818731 ! membrane docking GO:0022406 61 30 0,000 0,16550472 0,18809842 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,16550472 0,18800961 ! regulation of innate immune response GO:0045088 51 30 0,000 0,16550472 0,18792089 ! acute-phase response GO:0006953 49 30 0,000 0,16550472 0,18783224 ! myofibril assembly GO:0030239 47 30 0,000 0,16550472 0,18774369 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,16550472 0,18765521 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,16550472 0,18756682 ! phospholipid transport GO:0015914 51 30 0,000 0,16550472 0,18747851 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,16550472 0,18739029 ! eye morphogenesis GO:0048592 60 30 0,000 0,16550472 0,18730214 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,17052495 0,19289282 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,17052495 0,19280218 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,17052495 0,19271162 GO:0009799|determination of symmetry, ! inner ear morphogenesis GO:0042472 47 31 0,000 0,17052495 0,19262114 ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,17052495 0,19253075 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,17052495 0,19244045 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,17052495 0,19235022 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,17052495 0,19226009 ! peptide transport GO:0015833 55 31 0,000 0,17052495 0,19217004 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,17052495 0,19208007 ! iron ion homeostasis GO:0055072 54 31 0,000 0,17052495 0,19199019 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,17052495 0,19190039 ! mesoderm formation GO:0001707 69 31 0,000 0,17052495 0,19181067 ! natural killer cell activation GO:0030101 45 31 0,000 0,17052495 0,19172104 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,17052495 0,19163149 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,17052495 0,19154203 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,17052495 0,19145265 ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,17052495 0,19136335 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,17551514 0,19687153 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,17551514 0,19677979 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,17551514 0,19668814 ! cholesterol transport GO:0030301 56 32 0,000 0,17551514 0,19659657 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,17551514 0,19650509 ! spliceosome assembly GO:0000245 67 32 0,000 0,17551514 0,19641369 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,17551514 0,19632238 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,17551514 0,19623115 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,17551514 0,19614001 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,17551514 0,19604895 ! muscle cell development GO:0055001 49 32 0,000 0,17551514 0,19595798 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,17551514 0,19586709 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,17551514 0,19577628 ! BMP signaling pathway GO:0030509 64 32 0,000 0,17551514 0,19568556 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,17551514 0,19559492 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,17551514 0,19550437 ! gene silencing GO:0016458 65 32 0,000 0,17551514 0,1954139 ! protein targeting to membrane GO:0006612 68 33 0,000 0,18047548 0,20084367 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,18047548 0,20075081 ! ceramide metabolic process GO:0006672 64 33 0,000 0,18047548 0,20065804 ! formation of primary germ layer GO:0001704 72 33 0,000 0,18047548 0,20056536 ! cell fate specification GO:0001708 52 33 0,000 0,18047548 0,20047277 ! sterol transport GO:0015918 57 33 0,000 0,18047548 0,20038025 ! adult locomotory behavior GO:0008344 59 33 0,000 0,18047548 0,20028783 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,18047548 0,20019549 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,18540614 0,20557013 ! glial cell differentiation GO:0010001 63 34 0,000 0,18540614 0,20547544 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,18540614 0,20538084 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,18540614 0,20528632 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,18540614 0,20519189 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,18540614 0,20509755 ! mismatch repair GO:0006298 46 34 0,000 0,18540614 0,2050033 ! spermatid development GO:0007286 63 34 0,000 0,18540614 0,20490913 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,18540614 0,20481505 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,18540614 0,20472105 ! placenta development GO:0001890 53 34 0,000 0,18540614 0,20462714 ! negative regulation of secretion GO:0051048 63 35 0,000 0,1903073 0,2099401 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,1903073 0,20984388 ! odontogenesis GO:0042476 66 35 0,000 0,1903073 0,20974776 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,1903073 0,20965172 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,1903073 0,20955577 ! vesicle localization GO:0051648 64 35 0,000 0,1903073 0,20945991 ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,19517913 0,21472381 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,19517913 0,21462568 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,19517913 0,21452763 ! regulation of proteolysis GO:0030162 72 36 0,000 0,19517913 0,21442967 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,19517913 0,2143318 ! embryonic organ development GO:0048568 57 36 0,000 0,19517913 0,21423402 ! RNA export from nucleus GO:0006405 56 37 0,000 0,2000218 0,21944937 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,2000218 0,21934934 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,2000218 0,21924941 ! actomyosin structure organization GO:0031032 62 37 0,000 0,2000218 0,21914957 ! organic anion transport GO:0015711 68 37 0,000 0,2000218 0,21904982 ! tissue remodeling GO:0048771 76 37 0,000 0,2000218 0,21895016 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,2000218 0,2188506 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,2000218 0,21875112 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,2000218 0,21865173 GO:0015986|ATP synthesis coupled proton transport, ! glycogen metabolic process GO:0005977 61 37 0,000 0,2000218 0,21855243 ! spermatid differentiation GO:0048515 66 37 0,000 0,2000218 0,21845323 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,2048355 0,22360899 GO:0006956|complement activation, ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,2048355 0,22350758 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,2048355 0,22340626 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,2048355 0,22330504 ! nucleus organization GO:0006997 67 38 0,000 0,2048355 0,2232039 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,2048355 0,22310286 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,2048355 0,22300191 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,2048355 0,22290105 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,2048355 0,22280028 ! glucan metabolic process GO:0044042 62 38 0,000 0,2048355 0,2226996 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,20962039 0,22779886 ! ear morphogenesis GO:0042471 60 39 0,000 0,20962039 0,22769601 ! organic ether metabolic process GO:0018904 55 39 0,000 0,20962039 0,22759326 ! ion transmembrane transport GO:0034220 66 39 0,000 0,20962039 0,2274906 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,20962039 0,22738804 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,20962039 0,22728557 ! RNA modification GO:0009451 57 39 0,000 0,20962039 0,22718318 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,20962039 0,2270809 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,21437665 0,23212881 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,21437665 0,23202439 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,21437665 0,23192007 ! feeding behavior GO:0007631 59 40 0,000 0,21437665 0,23181583 ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,21437665 0,23171169 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,21910445 0,23671544 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,21910445 0,2366092 ! gliogenesis GO:0042063 88 41 0,000 0,21910445 0,23650305 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,21910445 0,23639699 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,21910445 0,23629103 ! regulation of tube size GO:0035150 71 42 0,000 0,22380394 0,24125102 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,22380394 0,24114299 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,22380394 0,24103504 ! regulation of protein secretion GO:0050708 71 42 0,000 0,22380394 0,2409272 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,22380394 0,24081945 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,22847531 0,24573608 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,22847531 0,24562628 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,22847531 0,24551657 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,22847531 0,24540697 ! striated muscle contraction GO:0006941 77 43 0,000 0,22847531 0,24529746 ! phagocytosis GO:0006909 90 43 0,000 0,22847531 0,24518805 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,22847531 0,24507874 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,23311873 0,24994815 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,23311873 0,24983682 ! biopolymer methylation GO:0043414 84 44 0,000 0,23311873 0,24972558 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,23311873 0,24961444 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,23311873 0,2495034 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,23773434 0,2543303 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,23773434 0,25421726 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,23773434 0,25410432 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,23773434 0,25399149 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,23773434 0,25387875 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,23773434 0,25376612 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,23773434 0,25365358 ! cell growth GO:0016049 84 45 0,000 0,23773434 0,25354115 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,24232234 0,25831969 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,24232234 0,25820529 ! response to calcium ion GO:0051592 81 47 0,000 0,24688287 0,26294828 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,24688287 0,26283194 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,24688287 0,26271569 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,24688287 0,26259955 ! JNK cascade GO:0007254 91 47 0,000 0,24688287 0,26248351 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,24688287 0,26236757 ! methylation GO:0032259 90 47 0,000 0,24688287 0,26225173 ! protein homooligomerization GO:0051260 76 47 0,000 0,24688287 0,262136 ! Notch signaling pathway GO:0007219 96 48 0,000 0,25141609 0,26683155 ! cellular component disassembly GO:0022411 86 48 0,000 0,25141609 0,2667139 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,25141609 0,26659635 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,25141609 0,26647891 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,25141609 0,26636157 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,25592219 0,27101619 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,25592219 0,27089696 ! regulation of ion transport GO:0043269 77 49 0,000 0,25592219 0,27077783 ! peptide metabolic process GO:0006518 76 49 0,000 0,25592219 0,2706588 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,25592219 0,27053989 ! endocrine system development GO:0035270 104 49 0,000 0,25592219 0,27042107 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,25592219 0,27030236 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,25592219 0,27018376 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,25592219 0,27006525 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,2604013 0,27467143 ! neuromuscular process GO:0050905 99 50 0,000 0,2604013 0,27455107 ! inner ear development GO:0048839 79 50 0,000 0,2604013 0,27443081 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,2604013 0,27431065 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,2604013 0,27419061 ! viral infectious cycle GO:0019058 99 51 0,000 0,26485361 0,27875668 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,26485361 0,27863479 ! excretion GO:0007588 83 51 0,000 0,26485361 0,27851301 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,26485361 0,27839134 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,26485361 0,27826977 ! regulation of cell shape GO:0008360 125 51 0,000 0,26485361 0,27814831 ! membrane fusion GO:0006944 110 52 0,000 0,26927925 0,28267272 ! amino acid activation GO:0043038 92 52 0,000 0,26927925 0,28254945 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 76 53 0,000 0,2736784 0,28704021 ! RNA catabolic process GO:0006401 93 53 0,000 0,2736784 0,28691514 ! regulation of translational initiation GO:0006446 82 53 0,000 0,2736784 0,28679017 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,2736784 0,28666532 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,2736784 0,28654057 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,2736784 0,28641594 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,2736784 0,28629141 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,27805121 0,29073934 ! cell recognition GO:0008037 85 54 0,000 0,27805121 0,29061304 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,27805121 0,29048685 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,27805121 0,29036077 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,27805121 0,2902348 ! chloride transport GO:0006821 90 55 0,000 0,28239784 0,29464406 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,28239784 0,29451635 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,28239784 0,29438874 ! gastrulation GO:0007369 112 55 0,000 0,28239784 0,29426124 ! RNA elongation GO:0006354 79 55 0,000 0,28239784 0,29413386 ! regulation of actin filament length GO:0030832 105 56 0,000 0,28671845 0,2985048 ! sensory perception of smell GO:0007608 80 56 0,000 0,28671845 0,29837569 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,28671845 0,29824669 ! proton transport GO:0015992 94 56 0,000 0,28671845 0,2981178 ! hydrogen transport GO:0006818 97 58 0,000 0,2952822 0,3068894 ! regulation of endocytosis GO:0030100 91 58 0,000 0,2952822 0,30675689 ! adult behavior GO:0030534 99 58 0,000 0,2952822 0,3066245 ! positive regulation of secretion GO:0051047 95 59 0,000 0,29952565 0,31089677 ! regulation of cellular component size GO:0032535 109 59 0,000 0,29952565 0,3107627 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,29952565 0,31062875 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,29952565 0,31049492 ! DNA catabolic process GO:0006308 86 59 0,000 0,29952565 0,3103612 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,30374369 0,31459635 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,30374369 0,31446098 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,30793647 0,31866458 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,30793647 0,31852758 ! mesoderm development GO:0007498 119 61 0,000 0,30793647 0,31839069 ! tRNA processing GO:0008033 89 61 0,000 0,30793647 0,31825393 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,30793647 0,31811728 ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,31624685 0,3265622 ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,31624685 0,3264221 ! detection of external stimulus GO:0009581 91 63 0,000 0,31624685 0,32628213 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,31624685 0,32614227 ! cell redox homeostasis GO:0045454 102 64 0,000 0,32036475 0,33024746 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,32036475 0,33010603 ! single fertilization GO:0007338 75 64 0,000 0,32036475 0,32996472 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,32445798 0,33403761 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,32445798 0,33389474 ! myeloid cell differentiation GO:0030099 111 65 0,000 0,32445798 0,33375199 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,3285267 0,33779284 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,33257105 0,34180519 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,33257105 0,34165924 ! activation of immune response GO:0002253 105 67 0,000 0,33257105 0,34151342 ! amino acid transport GO:0006865 125 68 0,000 0,33659117 0,34549418 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,33659117 0,34534684 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,33659117 0,34519964 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,34058721 0,34914905 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,34058721 0,34900035 ! antigen processing and presentation GO:0019882 104 69 0,000 0,34058721 0,34885178 ! amine catabolic process GO:0009310 117 71 0,000 0,34850762 0,35681248 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,34850762 0,35666071 ! regulation of immune effector process GO:0002697 137 71 0,000 0,34850762 0,35650907 ! acute inflammatory response GO:0002526 113 72 0,000 0,35243227 0,36037061 ! regulation of blood pressure GO:0008217 125 73 0,000 0,35633341 0,36420484 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,35633341 0,36405018 ! fertilization GO:0009566 90 73 0,000 0,35633341 0,36389566 ! transition metal ion transport GO:0000041 126 74 0,000 0,36021118 0,36769966 ! neurotransmitter transport GO:0006836 123 74 0,000 0,36021118 0,36754372 ! exocytosis GO:0006887 133 74 0,000 0,36021118 0,36738791 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,36021118 0,36723224 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,36021118 0,3670767 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,36406571 0,37084763 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,36406571 0,37069069 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,36789715 0,37443339 ! defense response to bacterium GO:0042742 89 76 0,000 0,36789715 0,37427507 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,37170563 0,37798975 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,37170563 0,37783006 ! blood coagulation GO:0007596 146 78 0,000 0,37549129 0,38151692 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,37549129 0,38135587 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,37925427 0,3850151 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,37925427 0,38485271 ! muscle cell differentiation GO:0042692 159 80 0,000 0,3829947 0,38848451 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,3829947 0,3883208 ! inorganic anion transport GO:0015698 138 80 0,000 0,3829947 0,38815722 ! digestion GO:0007586 112 81 0,000 0,38671271 0,39176033 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,38671271 0,39159545 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,39040844 0,39517153 ! hemostasis GO:0007599 158 84 0,000 0,39773359 0,40241675 ! response to unfolded protein GO:0006986 131 85 0,000 0,40136328 0,40591847 ! nucleosome assembly GO:0006334 122 85 0,000 0,40136328 0,40574792 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,40136328 0,40557751 ! amine biosynthetic process GO:0009309 138 86 0,000 0,4049712 0,40905152 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,4049712 0,40887986 ! chromatin assembly GO:0031497 124 86 0,000 0,4049712 0,40870835 ! amine transport GO:0015837 155 86 0,000 0,4049712 0,40853699 ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,4085575 0,41198213 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,41212231 0,41540271 ! cellular defense response GO:0006968 114 89 0,000 0,41566575 0,4187989 ! regulation of cell morphogenesis GO:0022604 215 89 0,000 0,41566575 0,4186236 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,41918794 0,42199422 ! sterol metabolic process GO:0016125 152 91 0,000 0,42268902 0,42534077 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,42268902 0,42516296 ! nucleosome organization GO:0034728 138 92 0,000 0,42616912 0,42848429 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,42616912 0,4283053 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,43306684 0,43505587 ! transcription initiation GO:0006352 153 94 0,000 0,43306684 0,4348743 ! forebrain development GO:0030900 188 95 0,000 0,43648471 0,43812358 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,43648471 0,43794088 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,4398821 0,44116562 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,4398821 0,4409818 ! positive regulation of immune response GO:0050778 156 96 0,000 0,4398821 0,44079814 ! detection of stimulus GO:0051606 151 96 0,000 0,4398821 0,44061463 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,44325911 0,4438125 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,44661588 0,44698744 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,44661588 0,44680158 GO:0016054|organic acid catabolic process, ! Golgi vesicle transport GO:0048193 207 99 0,000 0,44995252 0,44995252