pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6658-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! inner ear receptor cell differentiation GO:0060113 37 20 6,000 8,184E-11 1,969E-07 ! mechanoreceptor differentiation GO:0042490 40 22 6,000 1,778E-10 2,139E-07 ! lung development GO:0030324 144 67 7,000 3,696E-08 2,964E-05 ! cell growth GO:0016049 84 45 6,000 4,091E-08 2,461E-05 ! respiratory tube development GO:0030323 150 70 7,000 5,248E-08 2,525E-05 ! respiratory system development GO:0060541 153 72 7,000 6,57E-08 2,634E-05 ! inner ear development GO:0048839 79 50 6,000 8,725E-08 2,999E-05 ! auditory receptor cell differentiation GO:0042491 32 16 4,000 8,893E-08 2,675E-05 ! positive regulation of protein complex assembly GO:0031334 32 17 4,000 1,252E-07 3,348E-05 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 4,000 2,325E-07 5,593E-05 ! regulation of protein complex assembly GO:0043254 117 61 6,000 3,556E-07 7,777E-05 ! ear development GO:0043583 103 62 6,000 3,983E-07 7,986E-05 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 4,000 4,019E-07 7,439E-05 ! protein sumoylation GO:0016925 15 10 3,000 6,041E-07 1,038E-04 ! myeloid leukocyte differentiation GO:0002573 40 23 4,000 6,566E-07 1,053E-04 ! regulation of epithelial cell proliferation GO:0050678 111 43 5,000 7,669E-07 1,153E-04 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 4,000 1,024E-06 1,45E-04 ! regulation of gene-specific transcription GO:0032583 96 46 5,000 1,157E-06 1,546E-04 ! positive regulation of cell cycle GO:0045787 89 48 5,000 1,497E-06 1,895E-04 ! smooth muscle tissue development GO:0048745 28 5 2,000 4,015E-06 4,83E-04 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 2,000 4,015E-06 4,6E-04 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 5,000 4,186E-06 4,578E-04 ! positive regulation of gene-specific transcription GO:0043193 65 33 4,000 4,359E-06 4,56E-04 ! leukocyte differentiation GO:0002521 202 96 6,000 7,794E-06 7,814E-04 ! establishment or maintenance of cell polarity GO:0007163 83 37 4,000 7,814E-06 7,521E-04 ! male meiosis GO:0007140 7 6 2,000 7,986E-06 7,391E-04 ! nuclear migration GO:0007097 12 6 2,000 7,986E-06 7,117E-04 ! positive regulation of pseudopodium assembly GO:0031274 14 6 2,000 7,986E-06 6,863E-04 GO:0031272|regulation of pseudopodium assembly, ! regulation of protein localization GO:0032880 176 97 6,000 8,348E-06 6,926E-04 ! myeloid cell differentiation GO:0030099 111 65 5,000 9,067E-06 7,272E-04 ! positive regulation of protein ubiquitination GO:0031398 12 7 2,000 1,39E-05 1,079E-03 ! regulation of lipid kinase activity GO:0043550 13 7 2,000 1,39E-05 1,045E-03 ! regulation of protein export from nucleus GO:0046825 10 7 2,000 1,39E-05 1,013E-03 ! macrophage differentiation GO:0030225 11 7 2,000 1,39E-05 9,836E-04 ! centrosome duplication GO:0051298 13 7 2,000 1,39E-05 9,555E-04 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 2,000 2,212E-05 1,478E-03 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 2,000 2,212E-05 1,438E-03 ! establishment of nucleus localization GO:0040023 16 8 2,000 2,212E-05 1,4E-03 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 4,000 2,327E-05 1,436E-03 ! activation of protein kinase activity GO:0032147 147 79 5,000 2,798E-05 1,683E-03 ! positive regulation of phosphorylation GO:0042327 129 79 5,000 2,798E-05 1,642E-03 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 5,000 3,227E-05 1,849E-03 GO:0045937|positive regulation of phosphate metabolic process, ! response to hypoxia GO:0001666 171 81 5,000 3,227E-05 1,806E-03 ! artery development GO:0060840 24 9 2,000 3,299E-05 1,804E-03 GO:0048844|artery morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 2,000 3,299E-05 1,764E-03 ! liver development GO:0001889 53 25 3,000 3,333E-05 1,744E-03 ! response to oxygen levels GO:0070482 176 83 5,000 3,707E-05 1,898E-03 ! gland development GO:0048732 206 88 5,000 5,161E-05 2,587E-03 ! nucleus localization GO:0051647 19 11 2,000 6,41E-05 3,147E-03 ! negative regulation of transcription regulator activity GO:0090048 58 31 3,000 8,006E-05 3,853E-03 GO:0043433|negative regulation of transcription factor activity, ! regulation of cell projection assembly GO:0060491 30 12 2,000 8,5E-05 4,01E-03 ! positive regulation of cell growth GO:0030307 22 12 2,000 8,5E-05 3,933E-03 ! peripheral nervous system development GO:0007422 64 32 3,000 9,097E-05 4,13E-03 ! double-strand break repair via homologous recombination GO:0000724 19 13 2,000 1,099E-04 4,896E-03 GO:0000725|recombinational repair, ! regulation of epidermis development GO:0045682 19 13 2,000 1,099E-04 4,807E-03 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 2,000 1,099E-04 4,721E-03 ! cell projection assembly GO:0030031 120 66 4,000 1,345E-04 5,677E-03 ! negative regulation of protein kinase activity GO:0006469 130 67 4,000 1,445E-04 5,993E-03 ! homeostasis of number of cells GO:0048872 114 67 4,000 1,445E-04 5,891E-03 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 4,000 1,445E-04 5,793E-03 ! negative regulation of kinase activity GO:0033673 131 68 4,000 1,55E-04 6,113E-03 ! negative regulation of DNA binding GO:0043392 68 37 3,000 1,623E-04 6,298E-03 ! positive regulation of cell size GO:0045793 27 15 2,000 1,729E-04 6,603E-03 ! dopamine metabolic process GO:0042417 35 15 2,000 1,729E-04 6,5E-03 ! erythrocyte homeostasis GO:0034101 64 38 3,000 1,803E-04 6,675E-03 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 4,000 2,031E-04 7,403E-03 ! negative regulation of transferase activity GO:0051348 140 72 4,000 2,031E-04 7,293E-03 ! regulation of protein ubiquitination GO:0031396 25 16 2,000 2,116E-04 7,488E-03 ! filopodium assembly GO:0046847 32 16 2,000 2,116E-04 7,38E-03 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 2,000 2,116E-04 7,275E-03 ! positive regulation of neuron apoptosis GO:0043525 32 16 2,000 2,116E-04 7,172E-03 ! negative regulation of binding GO:0051100 72 40 3,000 2,207E-04 7,374E-03 ! regulation of transcription factor activity GO:0051090 126 74 4,000 2,31E-04 7,614E-03 GO:0090046|regulation of transcription regulator activity, ! meiosis GO:0007126 121 74 4,000 2,31E-04 7,511E-03 GO:0051327|M phase of meiotic cell cycle, ! T cell differentiation GO:0030217 81 41 3,000 2,431E-04 7,799E-03 ! meiotic cell cycle GO:0051321 122 75 4,000 2,46E-04 7,789E-03 ! negative regulation of cell cycle process GO:0010948 32 17 2,000 2,556E-04 7,986E-03 ! microspike assembly GO:0030035 36 17 2,000 2,556E-04 7,884E-03 ! regulation of intracellular protein transport GO:0033157 80 42 3,000 2,671E-04 8,136E-03 ! patterning of blood vessels GO:0001569 39 18 2,000 3,05E-04 9,174E-03 ! centrosome cycle GO:0007098 25 18 2,000 3,05E-04 9,06E-03 ! T cell activation GO:0042110 168 81 4,000 3,523E-04 0,01033687 ! estrogen receptor signaling pathway GO:0030520 38 19 2,000 3,602E-04 0,01044246 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 3,000 3,805E-04 0,01089936 ! camera-type eye morphogenesis GO:0048593 42 20 2,000 4,215E-04 0,01193052 ! collagen fibril organization GO:0030199 59 21 2,000 4,89E-04 0,01368182 ! negative regulation of intracellular transport GO:0032387 41 21 2,000 4,89E-04 0,01352456 ! positive regulation of protein modification process GO:0031401 136 88 4,000 5,165E-04 0,0141214 ! regulation of DNA binding GO:0051101 155 88 4,000 5,165E-04 0,01396273 ! hemoglobin biosynthetic process GO:0042541 7 5 1,000 5,427E-04 0,01450715 ! cell adhesion mediated by integrin GO:0033627 8 5 1,000 5,427E-04 0,01434773 ! embryonic camera-type eye development GO:0031076 10 5 1,000 5,427E-04 0,01419177 GO:0048596|embryonic camera-type eye morphogenesis, ! endochondral ossification GO:0001958 16 5 1,000 5,427E-04 0,01403917 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of viral genome replication GO:0045070 9 5 1,000 5,427E-04 0,01388982 ! regulation of retroviral genome replication GO:0045091 7 5 1,000 5,427E-04 0,01374361 ! neutrophil mediated immunity GO:0002446 7 5 1,000 5,427E-04 0,01360045 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 1,000 5,427E-04 0,01346024 ! histidine catabolic process GO:0006548 6 5 1,000 5,427E-04 0,01332289 GO:0009077|histidine family amino acid catabolic process, ! microvillus organization GO:0032528 7 5 1,000 5,427E-04 0,01318832 GO:0030033|microvillus assembly, ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 5,427E-04 0,01305643 ! early endosome to late endosome transport GO:0045022 12 5 1,000 5,427E-04 0,01292716 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 1,000 5,427E-04 0,01280042 ! meiotic chromosome segregation GO:0045132 7 5 1,000 5,427E-04 0,01267615 ! forebrain morphogenesis GO:0048853 13 5 1,000 5,427E-04 0,01255426 ! mitotic recombination GO:0006312 9 5 1,000 5,427E-04 0,0124347 ! positive regulation of chemokine production GO:0032722 8 5 1,000 5,427E-04 0,01231739 ! muscle cell proliferation GO:0033002 11 5 1,000 5,427E-04 0,01220227 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 1,000 5,427E-04 0,01208929 ! regulation of hair follicle development GO:0051797 10 5 1,000 5,427E-04 0,01197838 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 1,000 5,427E-04 0,01186948 ! glial cell migration GO:0008347 11 5 1,000 5,427E-04 0,01176255 ! inner cell mass cell proliferation GO:0001833 5 5 1,000 5,427E-04 0,01165753 ! regulation of sensory perception GO:0051931 7 5 1,000 5,427E-04 0,01155436 GO:0051930|regulation of sensory perception of pain, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 1,000 5,427E-04 0,01145301 GO:0022011|myelination in the peripheral nervous system, ! stem cell division GO:0017145 11 5 1,000 5,427E-04 0,01135342 GO:0048103|somatic stem cell division, ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 2,000 5,632E-04 0,01168077 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 3,000 5,661E-04 0,01164067 ! ossification GO:0001503 188 90 4,000 5,725E-04 0,01167351 ! bone development GO:0060348 189 91 4,000 6,022E-04 0,01217515 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 2,000 6,441E-04 0,01291412 ! synaptic vesicle transport GO:0048489 46 23 2,000 6,441E-04 0,01280739 ! response to UV GO:0009411 104 53 3,000 6,557E-04 0,01293031 ! negative regulation of phosphorylation GO:0042326 47 24 2,000 7,321E-04 0,01432031 ! interphase of mitotic cell cycle GO:0051329 209 95 4,000 7,325E-04 0,01421254 ! forebrain development GO:0030900 188 95 4,000 7,325E-04 0,01409884 ! regulation of Rho protein signal transduction GO:0035023 213 95 4,000 7,325E-04 0,01398695 ! positive regulation of actin filament polymerization GO:0030838 11 6 1,000 8,1E-04 0,01534533 ! erythrocyte maturation GO:0043249 7 6 1,000 8,1E-04 0,01522545 ! embryonic hemopoiesis GO:0035162 14 6 1,000 8,1E-04 0,01510742 ! equilibrioception GO:0050957 14 6 1,000 8,1E-04 0,01499121 ! regulation of smooth muscle cell differentiation GO:0051150 9 6 1,000 8,1E-04 0,01487677 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 1,000 8,1E-04 0,01476407 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! activation of MAPKKK activity GO:0000185 12 6 1,000 8,1E-04 0,01465306 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 1,000 8,1E-04 0,01454371 ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 1,000 8,1E-04 0,01443598 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! establishment of spindle localization GO:0051293 12 6 1,000 8,1E-04 0,01432983 GO:0051653|spindle localization, ! negative regulation of gliogenesis GO:0014014 18 6 1,000 8,1E-04 0,01422523 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 1,000 8,1E-04 0,01412215 ! response to UV-C GO:0010225 11 6 1,000 8,1E-04 0,01402055 ! astrocyte development GO:0014002 15 6 1,000 8,1E-04 0,01392041 ! enucleate erythrocyte differentiation GO:0043353 12 6 1,000 8,1E-04 0,01382168 ! Schwann cell development GO:0014044 15 6 1,000 8,1E-04 0,01372435 ! regulation of myeloid cell apoptosis GO:0033032 13 6 1,000 8,1E-04 0,01362837 ! myeloid dendritic cell activation GO:0001773 10 6 1,000 8,1E-04 0,01353373 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 1,000 8,1E-04 0,01344039 ! negative regulation of neuroblast proliferation GO:0007406 21 6 1,000 8,1E-04 0,01334834 ! vasculogenesis GO:0001570 46 25 2,000 8,274E-04 0,01354186 ! osteoblast differentiation GO:0001649 60 25 2,000 8,274E-04 0,01345036 ! interphase GO:0051325 213 98 4,000 8,432E-04 0,01361624 ! positive regulation of cell migration GO:0030335 126 57 3,000 8,642E-04 0,01386152 ! regulation of intracellular transport GO:0032386 101 57 3,000 8,642E-04 0,01376972 ! Golgi vesicle transport GO:0048193 207 99 4,000 8,828E-04 0,01397351 ! microtubule organizing center organization GO:0031023 39 26 2,000 9,302E-04 0,01462753 GO:0051297|centrosome organization, ! negative regulation of phosphorus metabolic process GO:0010563 51 26 2,000 9,302E-04 0,01453255 GO:0045936|negative regulation of phosphate metabolic process, ! blastocyst development GO:0001824 49 26 2,000 9,302E-04 0,01443879 ! establishment of organelle localization GO:0051656 109 59 3,000 9,842E-04 0,01517999 ! positive regulation of cell projection organization GO:0031346 58 27 2,000 1,041E-03 0,01594915 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 2,000 1,041E-03 0,01584821 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 1,000 1,128E-03 0,01707562 GO:0045346|regulation of MHC class II biosynthetic process, ! cytokinesis during cell cycle GO:0033205 11 7 1,000 1,128E-03 0,01696889 ! prostate gland development GO:0030850 13 7 1,000 1,128E-03 0,0168635 ! N-terminal protein amino acid acetylation GO:0006474 13 7 1,000 1,128E-03 0,0167594 ! adrenal gland development GO:0030325 17 7 1,000 1,128E-03 0,01665658 ! vesicle fusion GO:0006906 17 7 1,000 1,128E-03 0,01655502 ! positive regulation of mitotic cell cycle GO:0045931 12 7 1,000 1,128E-03 0,01645469 ! spindle checkpoint GO:0031577 15 7 1,000 1,128E-03 0,01635556 ! wound healing, spreading of epidermal cells GO:0035313 14 7 1,000 1,128E-03 0,01625762 ! negative regulation of nuclear division GO:0051784 14 7 1,000 1,128E-03 0,01616085 GO:0045839|negative regulation of mitosis, ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 1,000 1,128E-03 0,01606523 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of epidermal cell differentiation GO:0045604 8 7 1,000 1,128E-03 0,01597072 ! dopamine biosynthetic process GO:0042416 18 7 1,000 1,128E-03 0,01587733 ! embryonic heart tube development GO:0035050 10 7 1,000 1,128E-03 0,01578502 ! regulation of homeostatic process GO:0032844 134 62 3,000 1,186E-03 0,01648891 ! steroid hormone receptor signaling pathway GO:0030518 129 63 3,000 1,259E-03 0,01740465 ! negative regulation of protein complex assembly GO:0031333 59 29 2,000 1,286E-03 0,01768027 ! catechol metabolic process GO:0009712 54 29 2,000 1,286E-03 0,01757981 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! positive regulation of cell motion GO:0051272 146 64 3,000 1,335E-03 0,01814506 ! phenol metabolic process GO:0018958 55 30 2,000 1,421E-03 0,01920831 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 2,000 1,421E-03 0,019101 ! eye morphogenesis GO:0048592 60 30 2,000 1,421E-03 0,01899489 ! negative regulation of muscle cell differentiation GO:0051148 15 8 1,000 1,497E-03 0,01990217 ! endothelial cell differentiation GO:0045446 17 8 1,000 1,497E-03 0,01979282 ! hemoglobin metabolic process GO:0020027 13 8 1,000 1,497E-03 0,01968466 ! astrocyte differentiation GO:0048708 18 8 1,000 1,497E-03 0,01957768 ! histidine metabolic process GO:0006547 16 8 1,000 1,497E-03 0,01947185 GO:0009075|histidine family amino acid metabolic process, ! ER overload response GO:0006983 12 8 1,000 1,497E-03 0,01936717 ! embryonic eye morphogenesis GO:0048048 14 8 1,000 1,497E-03 0,0192636 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 1,000 1,497E-03 0,01916113 ! Schwann cell differentiation GO:0014037 19 8 1,000 1,497E-03 0,01905975 ! DNA topological change GO:0006265 12 8 1,000 1,497E-03 0,01895944 ! positive regulation of epidermis development GO:0045684 13 8 1,000 1,497E-03 0,01886017 ! neuromuscular process controlling posture GO:0050884 14 8 1,000 1,497E-03 0,01876194 ! blastocyst growth GO:0001832 19 8 1,000 1,497E-03 0,01866473 ! trophectodermal cell differentiation GO:0001829 13 8 1,000 1,497E-03 0,01856852 ! erythrocyte differentiation GO:0030218 55 31 2,000 1,565E-03 0,01930651 ! chromosome segregation GO:0007059 113 67 3,000 1,583E-03 0,01942741 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 3,000 1,672E-03 0,02041854 ! negative regulation of protein transport GO:0051224 69 33 2,000 1,879E-03 0,02282821 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 1,000 1,916E-03 0,02316 GO:0010469|regulation of receptor activity, ! regulation of mesenchymal cell proliferation GO:0010464 28 9 1,000 1,916E-03 0,0230442 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 1,000 1,916E-03 0,02292955 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 1,000 1,916E-03 0,02281604 ! erythrocyte development GO:0048821 15 9 1,000 1,916E-03 0,02270364 ! induction of an organ GO:0001759 14 9 1,000 1,916E-03 0,02259235 ! calcium-mediated signaling GO:0019722 62 35 2,000 2,229E-03 0,02616229 ! eye development GO:0001654 143 74 3,000 2,282E-03 0,02664935 ! organelle localization GO:0051640 136 74 3,000 2,282E-03 0,0265206 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 1,000 2,383E-03 0,0275618 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 1,000 2,383E-03 0,02742992 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 2,383E-03 0,02729931 ! regulation of phosphatase activity GO:0010921 28 10 1,000 2,383E-03 0,02716992 ! SMAD protein nuclear translocation GO:0007184 20 10 1,000 2,383E-03 0,02704176 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 1,000 2,383E-03 0,02691481 ! positive regulation of heart contraction GO:0045823 16 10 1,000 2,383E-03 0,02678904 ! negative regulation of striated muscle development GO:0045843 19 10 1,000 2,383E-03 0,02666444 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 1,000 2,383E-03 0,02654099 ! positive regulation of survival gene product expression GO:0045885 23 10 1,000 2,383E-03 0,02641868 ! myeloid leukocyte mediated immunity GO:0002444 14 10 1,000 2,383E-03 0,0262975 ! multicellular organism growth GO:0035264 18 10 1,000 2,383E-03 0,02617742 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 1,000 2,383E-03 0,02605843 ! regulation of bone resorption GO:0045124 25 10 1,000 2,383E-03 0,02594052 ! regulation of gliogenesis GO:0014013 23 10 1,000 2,383E-03 0,02582367 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 1,000 2,383E-03 0,02570787 ! DNA ligation GO:0006266 19 10 1,000 2,383E-03 0,0255931 ! negative regulation of MAPKKK cascade GO:0043409 20 10 1,000 2,383E-03 0,02547935 ! salivary gland development GO:0007431 27 10 1,000 2,383E-03 0,02536661 ! positive regulation of leukocyte migration GO:0002687 25 10 1,000 2,383E-03 0,02525486 ! methionine biosynthetic process GO:0009086 19 10 1,000 2,383E-03 0,0251441 ! positive regulation of viral reproduction GO:0048524 18 10 1,000 2,383E-03 0,0250343 ! oocyte development GO:0048599 17 10 1,000 2,383E-03 0,02492545 ! blastocyst formation GO:0001825 17 10 1,000 2,383E-03 0,02481755 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 1,000 2,383E-03 0,02471058 ! localization within membrane GO:0051668 20 10 1,000 2,383E-03 0,02460452 ! lymphocyte differentiation GO:0030098 167 75 3,000 2,396E-03 0,02463974 ! mitotic sister chromatid segregation GO:0000070 57 36 2,000 2,419E-03 0,02476169 ! embryonic organ development GO:0048568 57 36 2,000 2,419E-03 0,02465677 ! meiosis I GO:0007127 65 37 2,000 2,618E-03 0,02657378 ! sister chromatid segregation GO:0000819 58 37 2,000 2,618E-03 0,02646213 ! positive regulation of lymphocyte activation GO:0051251 127 77 3,000 2,638E-03 0,02655188 ! positive regulation of leukocyte proliferation GO:0070665 62 38 2,000 2,827E-03 0,02833595 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! positive regulation of DNA metabolic process GO:0051054 72 38 2,000 2,827E-03 0,02821837 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 3,000 2,895E-03 0,0287807 ! negative regulation of muscle development GO:0048635 20 11 1,000 2,898E-03 0,02869362 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 1,000 2,898E-03 0,02857603 GO:0046579|positive regulation of Ras protein signal transduction, ! thyroid gland development GO:0030878 26 11 1,000 2,898E-03 0,02845939 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 1,000 2,898E-03 0,0283437 ! blood vessel remodeling GO:0001974 29 11 1,000 2,898E-03 0,02822895 ! peptide or protein amino-terminal blocking GO:0018409 21 11 1,000 2,898E-03 0,02811512 ! adult heart development GO:0007512 14 11 1,000 2,898E-03 0,02800221 ! chondrocyte differentiation GO:0002062 24 11 1,000 2,898E-03 0,0278902 ! regulation of leukocyte migration GO:0002685 26 11 1,000 2,898E-03 0,02777909 ! oocyte differentiation GO:0009994 18 11 1,000 2,898E-03 0,02766885 ! thymus development GO:0048538 27 11 1,000 2,898E-03 0,02755949 ! developmental induction GO:0031128 19 11 1,000 2,898E-03 0,02745099 GO:0045168|cell-cell signaling involved in cell fate specification, ! lamellipodium assembly GO:0030032 20 11 1,000 2,898E-03 0,02734334 ! cytokinesis GO:0000910 72 40 2,000 3,274E-03 0,0307748 ! regulation of B cell proliferation GO:0030888 20 12 1,000 3,461E-03 0,03239751 ! folic acid and derivative biosynthetic process GO:0009396 21 12 1,000 3,461E-03 0,03227194 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 1,000 3,461E-03 0,03214734 ! membrane protein proteolysis GO:0033619 25 12 1,000 3,461E-03 0,0320237 GO:0006509|membrane protein ectodomain proteolysis, ! entry into host cell GO:0030260 32 12 1,000 3,461E-03 0,031901 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! regulation of interleukin-8 production GO:0032677 20 12 1,000 3,461E-03 0,03177924 ! histone acetylation GO:0016573 26 12 1,000 3,461E-03 0,03165841 ! autonomic nervous system development GO:0048483 24 12 1,000 3,461E-03 0,03153849 ! gland morphogenesis GO:0022612 29 12 1,000 3,461E-03 0,03141948 ! peptidyl-lysine modification GO:0018205 21 12 1,000 3,461E-03 0,03130136 ! T cell homeostasis GO:0043029 25 12 1,000 3,461E-03 0,03118412 ! spleen development GO:0048536 22 12 1,000 3,461E-03 0,03106777 ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 1,000 3,461E-03 0,03095227 ! gliogenesis GO:0042063 88 41 2,000 3,514E-03 0,03131165 ! positive regulation of cell activation GO:0050867 145 85 3,000 3,769E-03 0,03345885 GO:0002696|positive regulation of leukocyte activation, ! tube morphogenesis GO:0035239 176 86 3,000 3,93E-03 0,03476146 ! regulation of chemokine production GO:0032642 18 13 1,000 4,07E-03 0,0358679 ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 1,000 4,07E-03 0,035737 ! organelle fusion GO:0048284 32 13 1,000 4,07E-03 0,03560705 ! methionine metabolic process GO:0006555 27 13 1,000 4,07E-03 0,03547804 ! response to X-ray GO:0010165 25 13 1,000 4,07E-03 0,03534996 ! cellular carbohydrate catabolic process GO:0044275 15 13 1,000 4,07E-03 0,0352228 ! exocrine system development GO:0035272 32 13 1,000 4,07E-03 0,03509655 ! regulation of monooxygenase activity GO:0032768 33 13 1,000 4,07E-03 0,03497121 ! positive regulation of Ras GTPase activity GO:0032320 35 13 1,000 4,07E-03 0,03484675 ! embryonic placenta development GO:0001892 23 13 1,000 4,07E-03 0,03472318 ! positive regulation of protein polymerization GO:0032273 25 13 1,000 4,07E-03 0,03460049 ! acrosome reaction GO:0007340 18 13 1,000 4,07E-03 0,03447865 ! regulation of protein transport GO:0051223 154 87 3,000 4,096E-03 0,0345753 GO:0070201|regulation of establishment of protein localization, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 2,000 4,295E-03 0,03613048 ! double-strand break repair GO:0006302 81 44 2,000 4,295E-03 0,03600459 ! B cell differentiation GO:0030183 107 44 2,000 4,295E-03 0,03587957 ! JAK-STAT cascade GO:0007259 71 44 2,000 4,295E-03 0,03575542 ! branching morphogenesis of a tube GO:0048754 97 45 2,000 4,577E-03 0,03797018 ! induction of apoptosis by intracellular signals GO:0008629 93 45 2,000 4,577E-03 0,0378397 ! regulation of cell cycle process GO:0010564 149 90 3,000 4,621E-03 0,03807662 ! N-terminal protein amino acid modification GO:0031365 27 14 1,000 4,725E-03 0,03879916 ! reproductive cellular process GO:0048610 20 14 1,000 4,725E-03 0,03866719 ! regulation of S phase GO:0033261 23 14 1,000 4,725E-03 0,03853611 ! positive regulation of GTPase activity GO:0043547 36 14 1,000 4,725E-03 0,03840592 ! hair follicle morphogenesis GO:0031069 26 14 1,000 4,725E-03 0,03827661 ! palate development GO:0060021 31 14 1,000 4,725E-03 0,03814816 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 1,000 4,725E-03 0,03802058 ! regulation of mRNA processing GO:0050684 24 14 1,000 4,725E-03 0,03789384 ! embryo implantation GO:0007566 30 14 1,000 4,725E-03 0,03776795 ! negative regulation of protein import into nucleus GO:0042308 30 14 1,000 4,725E-03 0,03764289 ! T cell differentiation in the thymus GO:0033077 31 14 1,000 4,725E-03 0,03751866 ! response to gamma radiation GO:0010332 28 14 1,000 4,725E-03 0,03739524 ! regulation of erythrocyte differentiation GO:0045646 44 14 1,000 4,725E-03 0,03727263 ! catecholamine biosynthetic process GO:0042423 30 14 1,000 4,725E-03 0,03715083 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 1,000 5,425E-03 0,04251823 ! lymphocyte homeostasis GO:0002260 30 15 1,000 5,425E-03 0,04238018 ! epithelial to mesenchymal transition GO:0001837 28 15 1,000 5,425E-03 0,04224303 ! regulation of mast cell proliferation GO:0070666 81 48 2,000 5,488E-03 0,04259521 ! endocrine system development GO:0035270 104 49 2,000 5,814E-03 0,04498229 ! DNA-dependent DNA replication GO:0006261 74 49 2,000 5,814E-03 0,04483811 ! regulation of DNA metabolic process GO:0051052 178 97 3,000 6,019E-03 0,04627078 ! regulation of cell projection organization GO:0031344 121 50 2,000 6,152E-03 0,04713967 ! neuromuscular process GO:0050905 99 50 2,000 6,152E-03 0,04699002 ! sulfur amino acid biosynthetic process GO:0000097 28 16 1,000 6,17E-03 0,0469781 ! embryonic forelimb morphogenesis GO:0035115 28 16 1,000 6,17E-03 0,0468299 ! regulation of neurotransmitter secretion GO:0046928 33 16 1,000 6,17E-03 0,04668264 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 1,000 6,17E-03 0,0465363 ! startle response GO:0001964 28 16 1,000 6,17E-03 0,04639087 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 1,000 6,17E-03 0,04624635 ! activation of MAPKK activity GO:0000186 35 16 1,000 6,17E-03 0,04610273 ! regulation of dephosphorylation GO:0035303 43 16 1,000 6,17E-03 0,04596 ! negative regulation of immune response GO:0050777 35 16 1,000 6,17E-03 0,04581815 ! neuromuscular synaptic transmission GO:0007274 33 16 1,000 6,17E-03 0,04567717 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 1,000 6,17E-03 0,04553705 ! response to estrogen stimulus GO:0043627 93 51 2,000 6,501E-03 0,0478344 ! embryonic skeletal system development GO:0048706 85 51 2,000 6,501E-03 0,04768857 ! chromatin remodeling GO:0006338 109 51 2,000 6,501E-03 0,04754362 ! regulation of leukocyte proliferation GO:0070663 88 51 2,000 6,501E-03 0,04739954 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! cell cycle arrest GO:0007050 213 100 3,000 6,696E-03 0,04867352 ! regulation of angiogenesis GO:0045765 114 52 2,000 6,862E-03 0,04972802 ! positive regulation of growth GO:0045927 90 52 2,000 6,862E-03 0,04957869 ! morphogenesis of a branching structure GO:0001763 111 52 2,000 6,862E-03 0,04943025 ! signal complex assembly GO:0007172 41 17 1,000 6,959E-03 0,04997741 ! glial cell development GO:0021782 27 17 1,000 6,959E-03 0,04982866 ! regulation of muscle cell differentiation GO:0051147 33 17 1,000 6,959E-03 0,0496808 ! heart looping GO:0001947 30 17 1,000 6,959E-03 0,04953382 ! regulation of viral genome replication GO:0045069 28 17 1,000 6,959E-03 0,0493877 ! regulation of survival gene product expression GO:0045884 33 17 1,000 6,959E-03 0,04924244 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 1,000 6,959E-03 0,04909804 ! negative regulation of protein catabolic process GO:0042177 40 17 1,000 6,959E-03 0,04895448 ! DNA unwinding during replication GO:0006268 27 17 1,000 6,959E-03 0,04881175 ! neutrophil chemotaxis GO:0030593 27 17 1,000 6,959E-03 0,04866986 ! folic acid and derivative metabolic process GO:0006760 33 17 1,000 6,959E-03 0,04852879 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 2,000 7,234E-03 0,0503053 ! cell maturation GO:0048469 100 53 2,000 7,234E-03 0,05016033 ! regulation of neuron apoptosis GO:0043523 100 53 2,000 7,234E-03 0,05001619 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 7,79E-03 0,0537063 ! cellular response to hydrogen peroxide GO:0070301 23 18 1,000 7,79E-03 0,05355285 GO:0042744|hydrogen peroxide catabolic process, ! epidermis morphogenesis GO:0048730 40 18 1,000 7,79E-03 0,05340028 ! peptidyl-serine phosphorylation GO:0018105 38 18 1,000 7,79E-03 0,05324857 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 1,000 7,79E-03 0,05309773 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 1,000 7,79E-03 0,05294774 ! regulation of BMP signaling pathway GO:0030510 32 18 1,000 7,79E-03 0,05279859 ! regulation of protein catabolic process GO:0042176 116 55 2,000 8,014E-03 0,05416453 ! heart morphogenesis GO:0003007 97 55 2,000 8,014E-03 0,05401281 ! regulation of actin filament length GO:0030832 105 56 2,000 8,422E-03 0,05660327 ! nucleotide-excision repair GO:0006289 83 56 2,000 8,422E-03 0,0564456 ! regulation of DNA replication GO:0006275 101 56 2,000 8,422E-03 0,0562888 ! positive regulation of organelle organization GO:0010638 100 56 2,000 8,422E-03 0,05613288 ! lipid phosphorylation GO:0046834 35 19 1,000 8,664E-03 0,05758743 ! forelimb morphogenesis GO:0035136 32 19 1,000 8,664E-03 0,05742878 ! cerebral cortex development GO:0021987 36 19 1,000 8,664E-03 0,05727101 ! response to lipopolysaccharide GO:0032496 30 19 1,000 8,664E-03 0,0571141 ! regulation of endothelial cell migration GO:0010594 44 19 1,000 8,664E-03 0,05695806 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 1,000 8,664E-03 0,05680286 ! visual learning GO:0008542 36 19 1,000 8,664E-03 0,0566485 ! embryonic organ morphogenesis GO:0048562 26 19 1,000 8,664E-03 0,05649498 ! regulation of bone remodeling GO:0046850 137 57 2,000 8,842E-03 0,05749793 ! regulation of tissue remodeling GO:0034103 140 58 2,000 9,274E-03 0,0601443 ! positive regulation of ossification GO:0045778 47 20 1,000 9,58E-03 0,06196308 ! protein amino acid acetylation GO:0006473 39 20 1,000 9,58E-03 0,06179696 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 1,000 9,58E-03 0,06163173 ! DNA duplex unwinding GO:0032508 31 20 1,000 9,58E-03 0,06146737 GO:0032392|DNA geometric change, ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 1,000 9,58E-03 0,0613039 ! behavioral interaction between organisms GO:0051705 38 20 1,000 9,58E-03 0,06114129 ! ribosomal small subunit biogenesis GO:0042274 24 20 1,000 9,58E-03 0,06097954 ! negative regulation of angiogenesis GO:0016525 45 20 1,000 9,58E-03 0,06081864 ! peptidyl-serine modification GO:0018209 43 20 1,000 9,58E-03 0,06065859 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 1,000 9,58E-03 0,06049938 ! regulation of cellular component size GO:0032535 109 59 2,000 9,718E-03 0,06120953 ! skeletal system morphogenesis GO:0048705 105 59 2,000 9,718E-03 0,06104972 ! camera-type eye development GO:0043010 116 60 2,000 0,01017453 0,06374976 ! protein amino acid autophosphorylation GO:0046777 141 60 2,000 0,01017453 0,06358418 ! reciprocal meiotic recombination GO:0007131 39 21 1,000 0,0105373 0,06568071 ! hindlimb morphogenesis GO:0035137 43 21 1,000 0,0105373 0,06551099 ! regulation of neurotransmitter transport GO:0051588 42 21 1,000 0,0105373 0,06534215 ! cell aging GO:0007569 44 21 1,000 0,0105373 0,06517417 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 1,000 0,0105373 0,06500706 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 1,000 0,0105373 0,0648408 ! oogenesis GO:0048477 36 21 1,000 0,0105373 0,06467539 ! positive regulation of locomotion GO:0040017 39 21 1,000 0,0105373 0,06451082 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! positive regulation of protein catabolic process GO:0045732 38 22 1,000 0,01153472 0,0704379 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 1,000 0,01153472 0,07025957 ! sulfur amino acid metabolic process GO:0000096 41 22 1,000 0,01153472 0,07008215 ! positive regulation of bone remodeling GO:0046852 51 22 1,000 0,01153472 0,06990562 GO:0034105|positive regulation of tissue remodeling, ! regulation of chemotaxis GO:0050920 40 22 1,000 0,01153472 0,06972998 ! calcium-independent cell-cell adhesion GO:0016338 30 22 1,000 0,01153472 0,06955522 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 1,000 0,01153472 0,06938133 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 1,000 0,01153472 0,06920831 ! cellular response to reactive oxygen species GO:0034614 31 22 1,000 0,01153472 0,06903615 ! positive regulation of cytoskeleton organization GO:0051495 48 22 1,000 0,01153472 0,06886484 ! apoptotic nuclear changes GO:0030262 32 22 1,000 0,01153472 0,06869438 ! positive regulation of intracellular transport GO:0032388 37 22 1,000 0,01153472 0,06852477 ! positive regulation of B cell activation GO:0050871 38 22 1,000 0,01153472 0,06835599 ! protein stabilization GO:0050821 39 22 1,000 0,01153472 0,06818804 ! regulation of mitosis GO:0007088 105 63 2,000 0,01161725 0,06850758 GO:0051783|regulation of nuclear division, ! regulation of lipid metabolic process GO:0019216 115 63 2,000 0,01161725 0,06834008 ! positive regulation of DNA replication GO:0045740 43 23 1,000 0,01257192 0,07377571 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 1,000 0,01257192 0,0735962 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 0,01257192 0,07341757 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 1,000 0,01257192 0,0732398 ! visual behavior GO:0007632 42 23 1,000 0,01257192 0,0730629 ! regulation of cell-matrix adhesion GO:0001952 78 23 1,000 0,01257192 0,07288684 GO:0010810|regulation of cell-substrate adhesion, ! regulation of viral reproduction GO:0050792 38 23 1,000 0,01257192 0,07271163 ! negative regulation of cytokine production GO:0001818 40 23 1,000 0,01257192 0,07253726 ! negative regulation of catabolic process GO:0009895 50 23 1,000 0,01257192 0,07236373 ! acetyl-CoA catabolic process GO:0046356 36 23 1,000 0,01257192 0,07219102 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 1,000 0,01257192 0,07201914 ! extracellular matrix organization GO:0030198 133 66 2,000 0,01317179 0,07527628 ! developmental maturation GO:0021700 116 66 2,000 0,01317179 0,0750979 ! protein import into nucleus, translocation GO:0000060 46 24 1,000 0,01364827 0,07763058 ! positive regulation of fibroblast proliferation GO:0048146 43 24 1,000 0,01364827 0,07744749 ! spinal cord development GO:0021510 47 24 1,000 0,01364827 0,07726526 ! central nervous system neuron differentiation GO:0021953 50 24 1,000 0,01364827 0,07708388 ! regulation of behavior GO:0050795 43 24 1,000 0,01364827 0,07690336 ! regulation of alpha-beta T cell activation GO:0046634 42 24 1,000 0,01364827 0,07672368 ! pallium development GO:0021543 49 24 1,000 0,01364827 0,07654483 ! regulation of oxidoreductase activity GO:0051341 46 24 1,000 0,01364827 0,07636682 ! leukocyte homeostasis GO:0001776 44 24 1,000 0,01364827 0,07618964 ! aspartate family amino acid metabolic process GO:0009066 42 24 1,000 0,01364827 0,07601327 ! negative regulation of cell growth GO:0030308 132 67 2,000 0,01371503 0,07620868 ! positive regulation of T cell activation GO:0050870 109 67 2,000 0,01371503 0,07603308 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 2,000 0,01427087 0,07893266 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 1,000 0,01476313 0,08146809 ! myelination GO:0042552 45 25 1,000 0,01476313 0,08128167 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 1,000 0,01476313 0,08109609 ! negative regulation of DNA replication GO:0008156 42 25 1,000 0,01476313 0,08091136 ! chromosome condensation GO:0030261 45 25 1,000 0,01476313 0,08072747 ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 0,01476313 0,08054442 ! coenzyme catabolic process GO:0009109 39 25 1,000 0,01476313 0,08036219 ! negative regulation of cell development GO:0010721 73 25 1,000 0,01476313 0,08018079 GO:0050768|negative regulation of neurogenesis, ! hydrogen peroxide metabolic process GO:0042743 33 25 1,000 0,01476313 0,0800002 ! interaction with host GO:0051701 62 25 1,000 0,01476313 0,07982042 ! somitogenesis GO:0001756 43 25 1,000 0,01476313 0,07964145 ! neuromuscular process controlling balance GO:0050885 60 25 1,000 0,01476313 0,07946329 ! neural tube closure GO:0001843 49 25 1,000 0,01476313 0,07928591 GO:0060606|tube closure, ! negative regulation of cell size GO:0045792 134 69 2,000 0,01483934 0,0795177 ! urogenital system development GO:0001655 137 69 2,000 0,01483934 0,079341 ! initiation of viral infection GO:0019059 57 26 1,000 0,01591587 0,08490819 ! acetyl-CoA metabolic process GO:0006084 39 26 1,000 0,01591587 0,08472034 ! molting cycle process GO:0022404 50 26 1,000 0,01591587 0,08453332 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 1,000 0,01591587 0,08434713 ! regulation of transcription factor import into nucleus GO:0042990 54 26 1,000 0,01591587 0,08416175 ! insulin receptor signaling pathway GO:0008286 64 26 1,000 0,01591587 0,08397718 ! regulation of endothelial cell proliferation GO:0001936 57 26 1,000 0,01591587 0,08379343 ! cellular response to oxidative stress GO:0034599 39 26 1,000 0,01591587 0,08361047 ! positive regulation of MAPKKK cascade GO:0043410 47 26 1,000 0,01591587 0,08342831 ! positive regulation of nuclear division GO:0051785 40 26 1,000 0,01591587 0,08324695 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 1,000 0,01591587 0,08306637 ! reproductive structure development GO:0048608 113 71 2,000 0,0160143 0,08339914 ! B cell activation GO:0042113 160 71 2,000 0,0160143 0,08321902 ! regulation of MAPKKK cascade GO:0043408 142 71 2,000 0,0160143 0,08303966 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 2,000 0,01662084 0,08599946 ! regulation of fibroblast proliferation GO:0048145 52 27 1,000 0,01710589 0,08831923 ! protein amino acid acylation GO:0043543 55 27 1,000 0,01710589 0,08813011 ! primary neural tube formation GO:0014020 51 27 1,000 0,01710589 0,0879418 ! regulation of chromosome organization GO:0033044 42 27 1,000 0,01710589 0,08775429 ! learning or memory GO:0007611 147 73 2,000 0,01724013 0,08825479 ! regulation of actin cytoskeleton organization GO:0032956 149 74 2,000 0,01787218 0,09129608 ! circadian rhythm GO:0007623 50 28 1,000 0,01833255 0,09344939 ! negative regulation of protein modification process GO:0031400 60 28 1,000 0,01833255 0,09325182 ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 0,01833255 0,09305509 ! positive regulation of T cell differentiation GO:0045582 42 28 1,000 0,01833255 0,09285919 ! synaptogenesis GO:0007416 42 28 1,000 0,01833255 0,0926641 ! regulation of catabolic process GO:0009894 161 76 2,000 0,01917462 0,09671726 ! translational initiation GO:0006413 65 29 1,000 0,01959526 0,0986322 ! cellular iron ion homeostasis GO:0006879 51 29 1,000 0,01959526 0,09842629 ! response to organic cyclic substance GO:0014070 55 29 1,000 0,01959526 0,09822123 ! cellular response to extracellular stimulus GO:0031668 48 29 1,000 0,01959526 0,09801703 ! tissue homeostasis GO:0001894 48 29 1,000 0,01959526 0,09781368 GO:0048871|multicellular organismal homeostasis, ! regulation of actin filament-based process GO:0032970 152 77 2,000 0,01984504 0,09885542 ! negative regulation of organelle organization GO:0010639 161 78 2,000 0,02052828 0,10204759 ! response to steroid hormone stimulus GO:0048545 137 78 2,000 0,02052828 0,10183719 ! negative regulation of protein kinase cascade GO:0010741 68 30 1,000 0,02089342 0,1034353 ! ensheathment of neurons GO:0007272 57 30 1,000 0,02089342 0,10322291 GO:0008366|axon ensheathment, ! cofactor catabolic process GO:0051187 51 30 1,000 0,02089342 0,10301139 ! regulation of B cell activation GO:0050864 50 30 1,000 0,02089342 0,10280073 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 2,000 0,02122433 0,10421582 ! mRNA export from nucleus GO:0006406 48 31 1,000 0,02222643 0,10891402 ! positive regulation of T cell proliferation GO:0042102 52 31 1,000 0,02222643 0,10869265 ! iron ion homeostasis GO:0055072 54 31 1,000 0,02222643 0,10847218 ! natural killer cell activation GO:0030101 45 31 1,000 0,02222643 0,1082526 ! myeloid leukocyte activation GO:0002274 49 31 1,000 0,02222643 0,10803391 ! response to drug GO:0042493 143 82 2,000 0,02338946 0,11345776 ! response to hydrogen peroxide GO:0042542 50 32 1,000 0,02359371 0,11421824 ! spindle organization GO:0007051 46 32 1,000 0,02359371 0,11398888 ! metanephros development GO:0001656 74 32 1,000 0,02359371 0,11376045 ! response to ionizing radiation GO:0010212 65 32 1,000 0,02359371 0,11353293 ! response to mechanical stimulus GO:0009612 57 32 1,000 0,02359371 0,11330631 ! regulation of protein import into nucleus GO:0042306 63 32 1,000 0,02359371 0,1130806 ! negative regulation of MAP kinase activity GO:0043407 69 32 1,000 0,02359371 0,11285579 ! hindbrain development GO:0030902 61 32 1,000 0,02359371 0,11263187 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 1,000 0,02359371 0,11240884 ! positive regulation of catabolic process GO:0009896 64 32 1,000 0,02359371 0,11218669 ! regulation of ligase activity GO:0051340 142 84 2,000 0,024897 0,11815027 ! negative regulation of transport GO:0051051 153 84 2,000 0,024897 0,11791769 ! negative regulation of growth GO:0045926 155 84 2,000 0,024897 0,11768603 ! cell fate specification GO:0001708 52 33 1,000 0,02499468 0,11791609 ! leukocyte chemotaxis GO:0030595 50 33 1,000 0,02499468 0,11768533 GO:0060326|cell chemotaxis, ! adult locomotory behavior GO:0008344 59 33 1,000 0,02499468 0,11745548 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 1,000 0,02642877 0,12395249 ! glial cell differentiation GO:0010001 63 34 1,000 0,02642877 0,12371134 ! regulation of striated muscle tissue development GO:0016202 69 34 1,000 0,02642877 0,12347112 ! biogenic amine biosynthetic process GO:0042401 62 34 1,000 0,02642877 0,12323184 ! placenta development GO:0001890 53 34 1,000 0,02642877 0,12299348 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 1,000 0,02642877 0,12275604 ! amine biosynthetic process GO:0009309 138 86 2,000 0,02645578 0,12264472 ! regulation of muscle development GO:0048634 70 35 1,000 0,02789542 0,12906996 ! negative regulation of DNA metabolic process GO:0051053 61 35 1,000 0,02789542 0,12882222 ! embryonic skeletal system morphogenesis GO:0048704 59 35 1,000 0,02789542 0,12857544 ! female gonad development GO:0008585 58 35 1,000 0,02789542 0,1283296 ! telencephalon development GO:0021537 68 35 1,000 0,02789542 0,12808469 ! negative regulation of hydrolase activity GO:0051346 62 35 1,000 0,02789542 0,12784072 ! neural tube formation GO:0001841 67 35 1,000 0,02789542 0,12759768 ! regulation of neurological system process GO:0031644 148 88 2,000 0,02806571 0,12813303 ! regulation of cell adhesion GO:0030155 212 89 2,000 0,02888983 0,13164568 ! positive regulation of JAK-STAT cascade GO:0046427 50 36 1,000 0,02939406 0,13369018 ! positive regulation of cell development GO:0010720 80 36 1,000 0,02939406 0,13343794 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 1,000 0,02939406 0,13318664 ! aerobic respiration GO:0009060 55 36 1,000 0,02939406 0,13293629 ! androgen receptor signaling pathway GO:0030521 74 36 1,000 0,02939406 0,13268688 ! sex differentiation GO:0007548 145 90 2,000 0,02972668 0,13393705 ! RNA export from nucleus GO:0006405 56 37 1,000 0,03092414 0,13907193 ! tissue remodeling GO:0048771 76 37 1,000 0,03092414 0,13881247 ! regulation of protein stability GO:0031647 73 37 1,000 0,03092414 0,13855398 ! glycogen metabolic process GO:0005977 61 37 1,000 0,03092414 0,13829644 ! cellular response to insulin stimulus GO:0032869 82 37 1,000 0,03092414 0,13803986 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 2,000 0,03231347 0,14397444 GO:0010498|proteasomal protein catabolic process, ! mitotic cell cycle checkpoint GO:0007093 76 38 1,000 0,03248512 0,14447172 ! development of primary female sexual characteristics GO:0046545 67 38 1,000 0,03248512 0,14420516 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 1,000 0,03248512 0,14393959 ! embryonic epithelial tube formation GO:0001838 72 38 1,000 0,03248512 0,143675 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 1,000 0,03248512 0,14341137 ! glucan metabolic process GO:0044042 62 38 1,000 0,03248512 0,14314872 GO:0006073|cellular glucan metabolic process, ! biogenic amine metabolic process GO:0006576 155 94 2,000 0,03320106 0,14603609 ! female pregnancy GO:0007565 164 94 2,000 0,03320106 0,14576961 ! regulation of T cell activation GO:0050863 158 94 2,000 0,03320106 0,14550409 ! mammary gland development GO:0030879 86 39 1,000 0,03407646 0,149069 ! learning GO:0007612 77 39 1,000 0,03407646 0,14879846 ! segmentation GO:0035282 67 39 1,000 0,03407646 0,1485289 ! regulation of action potential in neuron GO:0019228 73 39 1,000 0,03407646 0,14826031 ! Rho protein signal transduction GO:0007266 74 39 1,000 0,03407646 0,14799269 ! mRNA transport GO:0051028 169 96 2,000 0,03501407 0,15179073 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 1,000 0,03569761 0,15447564 ! feeding behavior GO:0007631 59 40 1,000 0,03569761 0,15419831 ! multicellular organismal metabolic process GO:0044236 57 40 1,000 0,03569761 0,15392196 ! mesenchymal cell development GO:0014031 87 40 1,000 0,03569761 0,15364661 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,03664161 0,15742805 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,03664161 0,15714743 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,03664161 0,15686781 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,03664161 0,15658918 ! neuron fate determination GO:0048664 7 5 0,000 0,03664161 0,15631154 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,03664161 0,15603488 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,03664161 0,1557592 ! polyol transport GO:0015791 12 5 0,000 0,03664161 0,15548449 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,03664161 0,15521075 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,03664161 0,15493797 ! response to superoxide GO:0000303 10 5 0,000 0,03664161 0,15466615 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,03664161 0,15439528 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,03664161 0,15412536 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,03664161 0,15385638 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,03664161 0,15358834 ! female meiosis GO:0007143 7 5 0,000 0,03664161 0,15332123 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,03664161 0,15305505 ! cobalt ion transport GO:0006824 11 5 0,000 0,03664161 0,15278979 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,03664161 0,15252545 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,03664161 0,15226202 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,03664161 0,1519995 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,03664161 0,15173788 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,03664161 0,15147716 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,03664161 0,15121734 ! selenocysteine incorporation GO:0001514 12 5 0,000 0,03664161 0,1509584 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,03664161 0,15070035 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,03664161 0,15044319 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,03664161 0,1501869 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,03664161 0,14993148 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,03664161 0,14967692 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 0,03664161 0,14942323 ! negative chemotaxis GO:0050919 14 5 0,000 0,03664161 0,1491704 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,03664161 0,14891842 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,03664161 0,1486673 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,03664161 0,14841702 ! behavioral response to pain GO:0048266 9 5 0,000 0,03664161 0,14816758 ! clathrin coat assembly GO:0048268 14 5 0,000 0,03664161 0,14791897 ! Notch receptor processing GO:0007220 8 5 0,000 0,03664161 0,1476712 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,03664161 0,14742426 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,03664161 0,14717814 ! micturition GO:0060073 9 5 0,000 0,03664161 0,14693285 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,03664161 0,14668837 ! copulation GO:0007620 9 5 0,000 0,03664161 0,1464447 ! glial cell fate commitment GO:0021781 13 5 0,000 0,03664161 0,14620184 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,03664161 0,14595978 ! spermidine metabolic process GO:0008216 7 5 0,000 0,03664161 0,14571852 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,03664161 0,14547807 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,03664161 0,1452384 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,03664161 0,14499952 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,03664161 0,14476142 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,03664161 0,14452411 ! grooming behavior GO:0007625 6 5 0,000 0,03664161 0,14428757 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,03664161 0,14405181 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,03664161 0,14381681 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,03664161 0,14358259 ! response to protozoan GO:0001562 10 5 0,000 0,03664161 0,14334912 ! positive regulation of glycolysis GO:0045821 14 5 0,000 0,03664161 0,14311641 ! lymph vessel development GO:0001945 10 5 0,000 0,03664161 0,14288445 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,03664161 0,14265325 ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,03664161 0,14242279 ! parathyroid gland development GO:0060017 13 5 0,000 0,03664161 0,14219308 ! anagen GO:0042640 6 5 0,000 0,03664161 0,1419641 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,03664161 0,14173586 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,03664161 0,14150836 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,03664161 0,14128158 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,03664161 0,14105553 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,03664161 0,1408302 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,03664161 0,14060559 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,03664161 0,1403817 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,03664161 0,14015852 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,03664161 0,13993604 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,03664161 0,13971427 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,03664161 0,13949321 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,03664161 0,13927284 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,03664161 0,13905317 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 0,03664161 0,13883419 ! glycine biosynthetic process GO:0006545 7 5 0,000 0,03664161 0,13861589 ! valine metabolic process GO:0006573 10 5 0,000 0,03664161 0,13839828 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,03664161 0,13818136 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,03664161 0,13796511 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,03664161 0,13774954 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,03664161 0,13753465 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,03664161 0,13732042 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,03664161 0,13710685 ! polyol catabolic process GO:0046174 7 5 0,000 0,03664161 0,13689396 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,03664161 0,13668172 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,03664161 0,13647014 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,03664161 0,13625921 ! muscle cell migration GO:0014812 8 5 0,000 0,03664161 0,13604893 ! mitochondrial fission GO:0000266 8 5 0,000 0,03664161 0,1358393 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,03664161 0,13563032 ! mRNA transcription GO:0009299 9 5 0,000 0,03664161 0,13542198 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,03664161 0,13521428 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,03664161 0,13500721 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,03664161 0,13480078 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,03664161 0,13459497 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,03664161 0,1343898 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,03664161 0,13418525 ! response to food GO:0032094 6 5 0,000 0,03664161 0,13398132 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,03664161 0,13377801 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,03664161 0,13357531 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,03664161 0,13337323 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,03664161 0,13317176 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,03664161 0,1329709 ! forebrain neuron development GO:0021884 13 5 0,000 0,03664161 0,13277064 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,03664161 0,13257099 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,03664161 0,13237193 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,03664161 0,13217347 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,03664161 0,13197561 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,03664161 0,13177834 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,03664161 0,13158165 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,03664161 0,13138556 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,03664161 0,13119004 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,03664161 0,13099511 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,03664161 0,13080075 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,03664161 0,13060697 ! basic amino acid transport GO:0015802 11 5 0,000 0,03664161 0,13041377 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,03664161 0,13022113 ! depyrimidination GO:0045008 10 5 0,000 0,03664161 0,13002907 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,03664161 0,12983757 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,03664161 0,12964663 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,03664161 0,12945625 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,03664161 0,12926643 GO:0006882|cellular zinc ion homeostasis, ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,03664161 0,12907717 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,03664161 0,12888846 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,03664161 0,1287003 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,03664161 0,12851269 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,03664161 0,12832563 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,03664161 0,12813911 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,03664161 0,12795313 ! response to arsenic GO:0046685 10 5 0,000 0,03664161 0,12776769 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,03664161 0,12758279 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,03664161 0,12739842 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,03664161 0,12721459 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,03664161 0,12703128 ! response to cadmium ion GO:0046686 7 5 0,000 0,03664161 0,1268485 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,03664161 0,12666625 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,03664161 0,12648452 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,03664161 0,12630331 ! decidualization GO:0046697 11 5 0,000 0,03664161 0,12612261 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,03664161 0,12594244 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,03664161 0,12576278 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,03664161 0,12558363 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,03664161 0,12540499 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,03664161 0,12522686 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,03664161 0,12504923 ! neural tube patterning GO:0021532 7 5 0,000 0,03664161 0,12487211 ! embryonic cleavage GO:0040016 6 5 0,000 0,03664161 0,12469548 ! peroxisome fission GO:0016559 5 5 0,000 0,03664161 0,12451936 ! histone demethylation GO:0016577 10 5 0,000 0,03664161 0,12434373 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,03664161 0,1241686 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,03664161 0,12399396 ! metaphase plate congression GO:0051310 7 5 0,000 0,03664161 0,12381981 ! regulation of sterol transport GO:0032371 7 5 0,000 0,03664161 0,12364615 GO:0032374|regulation of cholesterol transport, ! enteric nervous system development GO:0048484 8 5 0,000 0,03664161 0,12347298 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,03664161 0,12330029 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,03664161 0,12312808 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,03664161 0,12295636 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,03664161 0,12278511 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,03664161 0,12261434 ! plasminogen activation GO:0031639 5 5 0,000 0,03664161 0,12244404 ! B cell homeostasis GO:0001782 13 5 0,000 0,03664161 0,12227421 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,03664161 0,12210486 ! metaphase GO:0051323 8 5 0,000 0,03664161 0,12193597 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,03664161 0,12176755 ! cellular response to nutrient GO:0031670 8 5 0,000 0,03664161 0,1215996 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,03664161 0,1214321 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,03664161 0,12126507 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,03664161 0,1210985 GO:0015991|ATP hydrolysis coupled proton transport, ! response to redox state GO:0051775 5 5 0,000 0,03664161 0,12093238 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,03664161 0,12076672 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,03664161 0,12060152 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,03664161 0,12043676 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,03664161 0,12027245 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,03664161 0,12010859 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,03664161 0,11994518 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,03664161 0,11978221 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,03664161 0,11961968 ! striatum development GO:0021756 9 5 0,000 0,03664161 0,1194576 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,03664161 0,11929595 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,03664161 0,11913474 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,03664161 0,11897396 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,03664161 0,11881362 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,03664161 0,11865371 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,03664161 0,11849423 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,03664161 0,11833518 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,03664161 0,11817655 ! neuroprotection GO:0043526 6 5 0,000 0,03664161 0,11801835 ! neural plate development GO:0001840 8 5 0,000 0,03664161 0,11786057 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,03664161 0,11770321 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,03664161 0,11754628 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,03664161 0,11738976 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,03664161 0,11723365 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,03664161 0,11707796 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,03664161 0,11692269 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,03664161 0,11676782 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,03664161 0,11661337 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,03664161 0,11645932 ! spindle assembly GO:0051225 6 5 0,000 0,03664161 0,11630568 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,03664161 0,11615245 GO:0016226|iron-sulfur cluster assembly, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,03664161 0,11599962 ! drug metabolic process GO:0017144 6 5 0,000 0,03664161 0,11584718 ! phospholipid scrambling GO:0017121 8 5 0,000 0,03664161 0,11569515 ! organ regeneration GO:0031100 7 5 0,000 0,03664161 0,11554352 ! carnitine metabolic process GO:0009437 7 5 0,000 0,03664161 0,11539229 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,03664161 0,11524145 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,03664161 0,115091 ! regulation of T cell proliferation GO:0042129 71 41 1,000 0,03734807 0,11715704 ! regulation of T cell differentiation GO:0045580 70 41 1,000 0,03734807 0,11700449 ! female gamete generation GO:0007292 61 41 1,000 0,03734807 0,11685234 ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 0,03902729 0,12194762 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 1,000 0,03902729 0,12178945 ! neuron migration GO:0001764 79 42 1,000 0,03902729 0,12163169 ! regulation of myeloid cell differentiation GO:0045637 98 42 1,000 0,03902729 0,12147434 ! epithelial cell differentiation GO:0030855 79 43 1,000 0,04073478 0,12662517 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 1,000 0,04073478 0,12646178 ! receptor-mediated endocytosis GO:0006898 88 43 1,000 0,04073478 0,12629881 ! energy reserve metabolic process GO:0006112 74 43 1,000 0,04073478 0,12613627 ! positive regulation of response to external stimulus GO:0032103 77 43 1,000 0,04073478 0,12597414 ! neural tube development GO:0021915 77 43 1,000 0,04073478 0,12581243 ! heterocycle biosynthetic process GO:0018130 69 43 1,000 0,04073478 0,12565113 ! developmental growth GO:0048589 82 44 1,000 0,04247002 0,13083593 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,04380793 0,13478501 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,04380793 0,13461287 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,04380793 0,13444117 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,04380793 0,13426991 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,04380793 0,13409908 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,04380793 0,13392869 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,04380793 0,13375873 ! sleep GO:0030431 13 6 0,000 0,04380793 0,1335892 ! response to oxygen radical GO:0000305 11 6 0,000 0,04380793 0,1334201 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,04380793 0,13325143 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,04380793 0,13308318 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,04380793 0,13291536 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,04380793 0,13274796 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,04380793 0,13258098 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,04380793 0,13241442 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,04380793 0,13224828 ! forebrain regionalization GO:0021871 8 6 0,000 0,04380793 0,13208255 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,04380793 0,13191724 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,04380793 0,13175235 ! response to zinc ion GO:0010043 9 6 0,000 0,04380793 0,13158786 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,04380793 0,13142379 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,04380793 0,13126012 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,04380793 0,13109686 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,04380793 0,13093401 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,04380793 0,13077156 ! malate metabolic process GO:0006108 11 6 0,000 0,04380793 0,13060951 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,04380793 0,13044787 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,04380793 0,13028662 ! protein refolding GO:0042026 15 6 0,000 0,04380793 0,13012577 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,04380793 0,12996532 ! opsonization GO:0008228 8 6 0,000 0,04380793 0,12980527 ! mating behavior GO:0007617 7 6 0,000 0,04380793 0,12964561 ! neuron remodeling GO:0016322 15 6 0,000 0,04380793 0,12948634 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,04380793 0,12932746 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,04380793 0,12916897 ! photoreceptor cell development GO:0042461 10 6 0,000 0,04380793 0,12901087 GO:0046530|photoreceptor cell differentiation, ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,04380793 0,12885315 ! response to interferon-gamma GO:0034341 15 6 0,000 0,04380793 0,12869582 ! toxin metabolic process GO:0009404 11 6 0,000 0,04380793 0,12853888 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,04380793 0,12838231 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,04380793 0,12822613 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,04380793 0,12807033 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,04380793 0,1279149 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,04380793 0,12775985 ! thymic T cell selection GO:0045061 12 6 0,000 0,04380793 0,12760518 ! protein lipoylation GO:0009249 10 6 0,000 0,04380793 0,12745088 ! cysteine metabolic process GO:0006534 10 6 0,000 0,04380793 0,12729695 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,04380793 0,1271434 ! glutamate catabolic process GO:0006538 10 6 0,000 0,04380793 0,12699021 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,04380793 0,1268374 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,04380793 0,12668495 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,04380793 0,12653287 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,04380793 0,12638115 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,04380793 0,12622979 ! hyperosmotic response GO:0006972 9 6 0,000 0,04380793 0,1260788 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,04380793 0,12592817 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,04380793 0,1257779 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,04380793 0,12562798 ! urea metabolic process GO:0019627 7 6 0,000 0,04380793 0,12547843 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,04380793 0,12532922 ! neutrophil activation GO:0042119 8 6 0,000 0,04380793 0,12518038 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,04380793 0,12503188 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,04380793 0,12488374 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,04380793 0,12473595 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,04380793 0,12458851 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,04380793 0,12444141 ! neuron apoptosis GO:0051402 9 6 0,000 0,04380793 0,12429467 ! nucleoside salvage GO:0043174 9 6 0,000 0,04380793 0,12414827 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,04380793 0,12400221 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,04380793 0,1238565 ! T cell mediated immunity GO:0002456 16 6 0,000 0,04380793 0,12371112 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,04380793 0,12356609 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 0,04380793 0,1234214 ! carnitine transport GO:0015879 10 6 0,000 0,04380793 0,12327705 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,04380793 0,12313303 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,04380793 0,12298936 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,04380793 0,12284601 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,04380793 0,122703 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,04380793 0,12256032 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,04380793 0,12241798 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,04380793 0,12227596 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,04380793 0,12213427 ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,04380793 0,12199291 ! neural nucleus development GO:0048857 14 6 0,000 0,04380793 0,12185188 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,04380793 0,12171118 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,04380793 0,12157079 ! interaction with symbiont GO:0051702 13 6 0,000 0,04380793 0,12143073 ! regulation of dendrite development GO:0050773 16 6 0,000 0,04380793 0,121291 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,04380793 0,12115158 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,04380793 0,12101249 ! response to copper ion GO:0046688 10 6 0,000 0,04380793 0,12087371 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,04380793 0,12073525 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,04380793 0,12059711 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,04380793 0,12045929 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,04380793 0,12032178 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,04380793 0,12018458 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,04380793 0,1200477 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,04380793 0,11991112 ! hair follicle maturation GO:0048820 7 6 0,000 0,04380793 0,11977486 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,04380793 0,11963891 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,04380793 0,11950326 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,04380793 0,11936792 ! subpallium development GO:0021544 10 6 0,000 0,04380793 0,11923289 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,04380793 0,11909817 ! histone ubiquitination GO:0016574 8 6 0,000 0,04380793 0,11896374 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,04380793 0,11882963 ! maintenance of organ identity GO:0048496 9 6 0,000 0,04380793 0,11869581 ! G2 phase GO:0051319 16 6 0,000 0,04380793 0,11856229 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,04380793 0,11842908 ! establishment of planar polarity GO:0001736 7 6 0,000 0,04380793 0,11829616 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,04380793 0,11816354 ! membrane to membrane docking GO:0022614 14 6 0,000 0,04380793 0,11803122 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,04380793 0,11789919 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,04380793 0,11776746 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,04380793 0,11763602 ! receptor internalization GO:0031623 10 6 0,000 0,04380793 0,11750488 ! neutrophil homeostasis GO:0001780 10 6 0,000 0,04380793 0,11737403 ! protein deubiquitination GO:0016579 14 6 0,000 0,04380793 0,11724347 ! protein destabilization GO:0031648 9 6 0,000 0,04380793 0,1171132 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,04380793 0,11698322 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,04380793 0,11685352 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,04380793 0,11672412 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,04380793 0,116595 ! progesterone metabolic process GO:0042448 10 6 0,000 0,04380793 0,11646616 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,04380793 0,11633761 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,04380793 0,11620935 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,04380793 0,11608136 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,04380793 0,11595366 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,04380793 0,11582624 ! determination of adult lifespan GO:0008340 15 6 0,000 0,04380793 0,1156991 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,04380793 0,11557223 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,04380793 0,11544565 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,04380793 0,11531934 ! catecholamine transport GO:0051937 9 6 0,000 0,04380793 0,11519331 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,04380793 0,11506755 ! sensory cilium assembly GO:0035058 10 6 0,000 0,04380793 0,11494207 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,04380793 0,11481686 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,04380793 0,11469192 ! maternal placenta development GO:0001893 12 6 0,000 0,04380793 0,11456726 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,04380793 0,11444286 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,04380793 0,11431874 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,04380793 0,11419488 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,04380793 0,1140713 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,04380793 0,11394798 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,04380793 0,11382492 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,04380793 0,11370213 ! regulation of actin filament polymerization GO:0030833 87 45 1,000 0,0442325 0,11468038 ! glycolysis GO:0006096 65 45 1,000 0,0442325 0,11455694 ! regulation of JAK-STAT cascade GO:0046425 70 45 1,000 0,0442325 0,11443376 ! leukocyte migration GO:0050900 68 45 1,000 0,0442325 0,11431084 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 1,000 0,04602173 0,11880718 ! negative regulation of cell migration GO:0030336 115 46 1,000 0,04602173 0,11867984 ! pigmentation GO:0043473 100 46 1,000 0,04602173 0,11855277 ! response to insulin stimulus GO:0032868 95 46 1,000 0,04602173 0,11842598 ! positive regulation of protein transport GO:0051222 72 46 1,000 0,04602173 0,11829945 ! response to calcium ion GO:0051592 81 47 1,000 0,04783722 0,12283496 ! endosome transport GO:0016197 108 47 1,000 0,04783722 0,12270401 ! positive regulation of DNA binding GO:0043388 73 47 1,000 0,04783722 0,12257333 ! positive regulation of cyclase activity GO:0031281 103 47 1,000 0,04783722 0,12244294 ! JNK cascade GO:0007254 91 47 1,000 0,04783722 0,12231282 ! protein homooligomerization GO:0051260 76 47 1,000 0,04783722 0,12218297 ! Notch signaling pathway GO:0007219 96 48 1,000 0,04967849 0,12675126 ! morphogenesis of embryonic epithelium GO:0016331 91 48 1,000 0,04967849 0,12661699 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 1,000 0,04967849 0,12648301 ! positive regulation of lyase activity GO:0051349 104 48 1,000 0,04967849 0,1263493 ! regulation of lymphocyte differentiation GO:0045619 81 48 1,000 0,04967849 0,12621588 ! tRNA transcription GO:0009304 14 7 0,000 0,05092118 0,12923666 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,05092118 0,12910048 ! regulation of helicase activity GO:0051095 15 7 0,000 0,05092118 0,12896458 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,05092118 0,12882897 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,05092118 0,12869365 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,05092118 0,12855861 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,05092118 0,12842385 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,05092118 0,12828938 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,05092118 0,12815518 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,05092118 0,12802127 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,05092118 0,12788763 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,05092118 0,12775428 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,05092118 0,1276212 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,05092118 0,1274884 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,05092118 0,12735588 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,05092118 0,12722363 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,05092118 0,12709165 ! glycolipid transport GO:0046836 10 7 0,000 0,05092118 0,12695995 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,05092118 0,12682852 GO:0051923|sulfation, ! neuron adhesion GO:0007158 12 7 0,000 0,05092118 0,12669737 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,05092118 0,12656648 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,05092118 0,12643587 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,05092118 0,12630552 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,05092118 0,12617544 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,05092118 0,12604563 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,05092118 0,12591609 ! mRNA stabilization GO:0048255 18 7 0,000 0,05092118 0,12578681 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,05092118 0,1256578 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,05092118 0,12552905 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,05092118 0,12540057 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,05092118 0,12527234 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,05092118 0,12514439 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,05092118 0,12501669 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,05092118 0,12488925 ! lipoprotein transport GO:0042953 14 7 0,000 0,05092118 0,12476207 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,05092118 0,12463515 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,05092118 0,12450849 ! rhythmic behavior GO:0007622 15 7 0,000 0,05092118 0,12438208 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,05092118 0,12425594 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,05092118 0,12413004 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,05092118 0,12400441 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,05092118 0,12387902 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,05092118 0,12375389 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,05092118 0,12362901 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,05092118 0,12350439 ! mechanosensory behavior GO:0007638 14 7 0,000 0,05092118 0,12338001 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,05092118 0,12325589 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,05092118 0,12313201 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,05092118 0,12300839 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,05092118 0,12288501 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,05092118 0,12276188 ! spinal cord patterning GO:0021511 13 7 0,000 0,05092118 0,12263899 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,05092118 0,12251635 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,05092118 0,12239396 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,05092118 0,12227181 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,05092118 0,1221499 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,05092118 0,12202824 ! ovulation GO:0030728 9 7 0,000 0,05092118 0,12190682 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,05092118 0,12178564 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,05092118 0,1216647 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,05092118 0,121544 ! microtubule nucleation GO:0007020 20 7 0,000 0,05092118 0,12142354 ! proline biosynthetic process GO:0006561 10 7 0,000 0,05092118 0,12130332 ! thyroid hormone generation GO:0006590 13 7 0,000 0,05092118 0,12118334 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,05092118 0,12106359 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,05092118 0,12094408 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,05092118 0,12082481 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,05092118 0,12070577 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,05092118 0,12058696 ! galactose metabolic process GO:0006012 13 7 0,000 0,05092118 0,12046839 ! response to dietary excess GO:0002021 8 7 0,000 0,05092118 0,12035005 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,05092118 0,12023195 ! intracellular pH reduction GO:0051452 11 7 0,000 0,05092118 0,12011407 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,05092118 0,11999643 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,05092118 0,11987902 ! organ growth GO:0035265 15 7 0,000 0,05092118 0,11976183 ! purine salvage GO:0043101 10 7 0,000 0,05092118 0,11964488 ! nucleoside transport GO:0015858 8 7 0,000 0,05092118 0,11952815 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,05092118 0,11941165 ! parturition GO:0007567 14 7 0,000 0,05092118 0,11929538 ! rRNA modification GO:0000154 14 7 0,000 0,05092118 0,11917933 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,05092118 0,11906351 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,05092118 0,11894792 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,05092118 0,11883254 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,05092118 0,1187174 GO:0046676|negative regulation of insulin secretion, ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,05092118 0,11860247 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 0,05092118 0,11848777 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,05092118 0,11837329 ! fibrinolysis GO:0042730 10 7 0,000 0,05092118 0,11825903 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,05092118 0,11814499 ! eating behavior GO:0042755 7 7 0,000 0,05092118 0,11803117 ! B cell lineage commitment GO:0002326 21 7 0,000 0,05092118 0,11791757 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,05092118 0,11780419 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,05092118 0,11769102 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,05092118 0,11757807 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,05092118 0,11746534 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,05092118 0,11735283 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,05092118 0,11724053 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,05092118 0,11712844 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,05092118 0,11701657 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,05092118 0,11690492 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,05092118 0,11679347 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,05092118 0,11668224 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,05092118 0,11657122 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,05092118 0,11646041 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,05092118 0,11634981 ! regulation of meiosis GO:0040020 12 7 0,000 0,05092118 0,11623942 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,05092118 0,11612924 ! T cell lineage commitment GO:0002360 16 7 0,000 0,05092118 0,11601927 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,05092118 0,11590951 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,05092118 0,11579996 ! oxygen homeostasis GO:0032364 12 7 0,000 0,05092118 0,11569061 ! transcription termination GO:0006353 13 7 0,000 0,05092118 0,11558147 ! response to tumor cell GO:0002347 13 7 0,000 0,05092118 0,11547253 ! regulation of respiratory burst GO:0060263 11 7 0,000 0,05092118 0,1153638 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,05092118 0,11525527 ! anaphase GO:0051322 17 7 0,000 0,05092118 0,11514695 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,05092118 0,11503883 ! axonal fasciculation GO:0007413 18 7 0,000 0,05092118 0,11493091 ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,05092118 0,1148232 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,05092118 0,11471569 ! diuresis GO:0030146 12 7 0,000 0,05092118 0,11460838 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,05092118 0,11450126 ! thiamin metabolic process GO:0006772 7 7 0,000 0,05092118 0,11439435 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,05092118 0,11428764 ! antibiotic transport GO:0042891 9 7 0,000 0,05092118 0,11418113 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,05092118 0,11407482 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,05092118 0,1139687 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,05092118 0,11386278 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,05092118 0,11375706 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,05092118 0,11365153 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,05092118 0,1135462 ! lymph node development GO:0048535 10 7 0,000 0,05092118 0,11344107 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,05092118 0,11333613 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,05092118 0,11323138 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,05092118 0,11312683 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,05092118 0,11302247 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,05092118 0,1129183 ! adult feeding behavior GO:0008343 9 7 0,000 0,05092118 0,11281432 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,05092118 0,11271054 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,05092118 0,11260694 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,05092118 0,11250354 ! muscle adaptation GO:0043500 14 7 0,000 0,05092118 0,11240032 ! retina homeostasis GO:0001895 12 7 0,000 0,05092118 0,1122973 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,05092118 0,11219446 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,05092118 0,11209181 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,05092118 0,11198935 ! protein prenylation GO:0018342 18 7 0,000 0,05092118 0,11188708 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,05092118 0,11178499 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,05092118 0,11168309 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,05092118 0,11158138 ! regulation of action potential GO:0001508 95 49 1,000 0,05154504 0,11284566 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 1,000 0,05154504 0,11274307 ! regulation of ossification GO:0030278 117 50 1,000 0,05343642 0,11677386 ! histone modification GO:0016570 91 50 1,000 0,05343642 0,1166679 ! negative regulation of immune system process GO:0002683 95 50 1,000 0,05343642 0,11656212 ! positive regulation of cytokine production GO:0001819 86 50 1,000 0,05343642 0,11645654 ! positive regulation of binding GO:0051099 78 51 1,000 0,05535214 0,1205224 ! viral infectious cycle GO:0019058 99 51 1,000 0,05535214 0,12041343 ! cellular amino acid biosynthetic process GO:0008652 75 51 1,000 0,05535214 0,12030466 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 1,000 0,05535214 0,12019608 ! vesicle organization GO:0016050 107 51 1,000 0,05535214 0,12008769 ! epithelial tube morphogenesis GO:0060562 98 51 1,000 0,05535214 0,11997951 ! membrane fusion GO:0006944 110 52 1,000 0,05729175 0,12407197 ! covalent chromatin modification GO:0016569 101 52 1,000 0,05729175 0,12396039 ! cartilage development GO:0051216 90 52 1,000 0,05729175 0,12384902 ! synapse organization GO:0050808 85 52 1,000 0,05729175 0,12373784 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,05798174 0,12511576 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,05798174 0,12500365 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,05798174 0,12489174 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,05798174 0,12478003 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,05798174 0,12466852 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,05798174 0,12455721 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,05798174 0,1244461 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,05798174 0,12433518 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,05798174 0,12422447 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,05798174 0,12411395 ! meiotic prophase I GO:0007128 13 8 0,000 0,05798174 0,12400362 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,05798174 0,1238935 ! oligopeptide transport GO:0006857 15 8 0,000 0,05798174 0,12378356 ! UTP metabolic process GO:0046051 8 8 0,000 0,05798174 0,12367383 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,05798174 0,12356428 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,05798174 0,12345493 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,05798174 0,12334578 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,05798174 0,12323682 ! succinate metabolic process GO:0006105 14 8 0,000 0,05798174 0,12312805 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,05798174 0,12301947 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,05798174 0,12291108 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,05798174 0,12280288 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,05798174 0,12269488 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,05798174 0,12258706 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,05798174 0,12247943 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,05798174 0,122372 ! reflex GO:0060004 16 8 0,000 0,05798174 0,12226475 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,05798174 0,12215768 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,05798174 0,12205081 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,05798174 0,12194412 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,05798174 0,12183762 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,05798174 0,12173131 ! pigment granule organization GO:0048753 16 8 0,000 0,05798174 0,12162518 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,05798174 0,12151923 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,05798174 0,12141347 ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,05798174 0,12130789 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,05798174 0,1212025 ! glycine catabolic process GO:0006546 13 8 0,000 0,05798174 0,12109729 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,05798174 0,12099226 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,05798174 0,12088741 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,05798174 0,12078275 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,05798174 0,12067827 ! melanin metabolic process GO:0006582 15 8 0,000 0,05798174 0,12057396 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,05798174 0,12046984 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,05798174 0,1203659 ! macrophage activation GO:0042116 12 8 0,000 0,05798174 0,12026213 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,05798174 0,12015855 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,05798174 0,12005514 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,05798174 0,11995191 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,05798174 0,11984886 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,05798174 0,11974599 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,05798174 0,11964329 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,05798174 0,11954077 ! osteoblast development GO:0002076 16 8 0,000 0,05798174 0,11943842 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,05798174 0,11933625 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,05798174 0,11923425 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,05798174 0,11913243 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,05798174 0,11903078 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,05798174 0,11892931 ! response to UV-B GO:0010224 16 8 0,000 0,05798174 0,118828 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,05798174 0,11872687 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,05798174 0,11862592 ! intermediate filament organization GO:0045109 12 8 0,000 0,05798174 0,11852513 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,05798174 0,11842451 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,05798174 0,11832407 ! cellular extravasation GO:0045123 12 8 0,000 0,05798174 0,11822379 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,05798174 0,11812369 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,05798174 0,11802375 ! response to antibiotic GO:0046677 11 8 0,000 0,05798174 0,11792399 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,05798174 0,11782439 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,05798174 0,11772496 ! response to tropane GO:0014073 15 8 0,000 0,05798174 0,1176257 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,05798174 0,1175266 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 0,000 0,05798174 0,11742767 ! melanosome transport GO:0032402 13 8 0,000 0,05798174 0,11732891 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,05798174 0,11723032 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,05798174 0,11713189 ! mast cell activation GO:0045576 14 8 0,000 0,05798174 0,11703362 ! multicellular organismal aging GO:0010259 18 8 0,000 0,05798174 0,11693552 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,05798174 0,11683758 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,05798174 0,11673981 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,05798174 0,1166422 ! nucleosome disassembly GO:0006337 14 8 0,000 0,05798174 0,11654476 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,05798174 0,11644748 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,05798174 0,11635036 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,05798174 0,1162534 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,05798174 0,1161566 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,05798174 0,11605996 ! intracellular lipid transport GO:0032365 13 8 0,000 0,05798174 0,11596349 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,05798174 0,11586717 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,05798174 0,11577102 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,05798174 0,11567502 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,05798174 0,11557918 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,05798174 0,11548351 ! hormone catabolic process GO:0042447 17 8 0,000 0,05798174 0,11538799 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,05798174 0,11529263 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,05798174 0,11519742 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,05798174 0,11510237 ! ATP catabolic process GO:0006200 11 8 0,000 0,05798174 0,11500748 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,05798174 0,11491275 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,05798174 0,11481817 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,05798174 0,11472375 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,05798174 0,11462948 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,05798174 0,11453537 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,05798174 0,11444141 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,05798174 0,1143476 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,05798174 0,11425395 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,05798174 0,11416046 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,05798174 0,11406711 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,05798174 0,11397392 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,05798174 0,11388088 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,05798174 0,11378799 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,05798174 0,11369525 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,05798174 0,11360267 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,05798174 0,11351023 ! regulation of protein polymerization GO:0032271 103 53 1,000 0,05925479 0,11590815 ! activation of phospholipase C activity GO:0007202 103 54 1,000 0,06124081 0,11969568 GO:0010863|positive regulation of phospholipase C activity, ! heterocycle catabolic process GO:0046700 85 54 1,000 0,06124081 0,11959852 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 1,000 0,06124081 0,11950152 ! glucose catabolic process GO:0006007 82 55 1,000 0,06324935 0,12332086 ! cellular polysaccharide metabolic process GO:0044264 86 55 1,000 0,06324935 0,123221 ! sulfur compound biosynthetic process GO:0044272 93 55 1,000 0,06324935 0,12312131 ! positive regulation of phospholipase activity GO:0010518 104 55 1,000 0,06324935 0,12302178 ! aging GO:0007568 103 55 1,000 0,06324935 0,12292241 ! RNA elongation GO:0006354 79 55 1,000 0,06324935 0,1228232 ! nuclear export GO:0051168 97 55 1,000 0,06324935 0,12272414 ! negative regulation of cell motion GO:0051271 134 55 1,000 0,06324935 0,12262525 ! regulation of developmental growth GO:0048638 15 9 0,000 0,06499002 0,12589854 ! axon extension GO:0048675 15 9 0,000 0,06499002 0,12579725 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,06499002 0,12569613 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,06499002 0,12559517 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,06499002 0,12549437 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,06499002 0,12539373 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,06499002 0,12529325 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,06499002 0,12519294 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,06499002 0,12509278 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,06499002 0,12499279 ! phosphate transport GO:0006817 19 9 0,000 0,06499002 0,12489296 ! reproductive behavior GO:0019098 19 9 0,000 0,06499002 0,12479328 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,06499002 0,12469376 ! CTP metabolic process GO:0046036 9 9 0,000 0,06499002 0,12459441 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,06499002 0,12449521 ! GTP metabolic process GO:0046039 9 9 0,000 0,06499002 0,12439617 ! RNA methylation GO:0001510 15 9 0,000 0,06499002 0,12429728 ! elastic fiber assembly GO:0048251 15 9 0,000 0,06499002 0,12419856 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,06499002 0,12409998 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,06499002 0,12400157 ! regulation of histone modification GO:0031056 12 9 0,000 0,06499002 0,12390331 ! regulation of glycolysis GO:0006110 21 9 0,000 0,06499002 0,12380521 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,06499002 0,12370726 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,06499002 0,12360947 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,06499002 0,12351183 ! chemosensory behavior GO:0007635 20 9 0,000 0,06499002 0,12341435 ! microtubule bundle formation GO:0001578 21 9 0,000 0,06499002 0,12331702 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,06499002 0,12321984 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,06499002 0,12312282 ! leukocyte degranulation GO:0043299 16 9 0,000 0,06499002 0,12302595 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,06499002 0,12292923 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,06499002 0,12283266 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,06499002 0,12273625 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,06499002 0,12263999 ! protein targeting to ER GO:0045047 22 9 0,000 0,06499002 0,12254387 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,06499002 0,12244791 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,06499002 0,1223521 ! T cell selection GO:0045058 23 9 0,000 0,06499002 0,12225644 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,06499002 0,12216092 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,06499002 0,12206556 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,06499002 0,12197034 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,06499002 0,12187528 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,06499002 0,12178036 ! mannose metabolic process GO:0006013 13 9 0,000 0,06499002 0,12168559 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,06499002 0,12159096 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,06499002 0,12149649 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,06499002 0,12140216 ! receptor clustering GO:0043113 18 9 0,000 0,06499002 0,12130798 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,06499002 0,12121394 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,06499002 0,12112005 ! ruffle organization GO:0031529 15 9 0,000 0,06499002 0,1210263 ! retinol metabolic process GO:0042572 18 9 0,000 0,06499002 0,1209327 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,06499002 0,12083924 ! behavioral fear response GO:0001662 22 9 0,000 0,06499002 0,12074593 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,06499002 0,12065276 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,06499002 0,12055974 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,06499002 0,12046686 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 0,06499002 0,12037412 ! protein heterooligomerization GO:0051291 16 9 0,000 0,06499002 0,12028152 ! oligodendrocyte development GO:0014003 10 9 0,000 0,06499002 0,12018907 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,06499002 0,12009676 ! segment specification GO:0007379 13 9 0,000 0,06499002 0,12000459 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,06499002 0,11991256 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,06499002 0,11982068 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,06499002 0,11972893 ! response to amine stimulus GO:0014075 13 9 0,000 0,06499002 0,11963732 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,06499002 0,11954586 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,06499002 0,11945453 ! gas homeostasis GO:0033483 16 9 0,000 0,06499002 0,11936334 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,06499002 0,1192723 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,06499002 0,11918139 ! renal water homeostasis GO:0003091 14 9 0,000 0,06499002 0,11909062 ! postreplication repair GO:0006301 22 9 0,000 0,06499002 0,11899999 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,06499002 0,11890949 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,06499002 0,11881913 ! icosanoid secretion GO:0032309 15 9 0,000 0,06499002 0,11872891 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,06499002 0,11863883 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 15 9 0,000 0,06499002 0,11854889 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,06499002 0,11845908 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,06499002 0,1183694 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,06499002 0,11827986 ! sterol catabolic process GO:0016127 11 9 0,000 0,06499002 0,11819046 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,06499002 0,11810119 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,06499002 0,11801206 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,06499002 0,11792306 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,06499002 0,1178342 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,06499002 0,11774547 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,06499002 0,11765687 ! musculoskeletal movement GO:0050881 14 9 0,000 0,06499002 0,11756841 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,06499002 0,11748008 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,06499002 0,11739188 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,06499002 0,11730381 ! purine base metabolic process GO:0006144 21 9 0,000 0,06499002 0,11721588 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,06499002 0,11712808 ! pigment granule transport GO:0051904 17 9 0,000 0,06499002 0,1170404 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,06499002 0,11695287 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,06499002 0,11686546 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,06499002 0,11677818 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,06499002 0,11669103 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,06499002 0,11660401 ! mitochondrion localization GO:0051646 15 9 0,000 0,06499002 0,11651712 ! lipid modification GO:0030258 97 57 1,000 0,06733227 0,12062654 ! regulation of phospholipase activity GO:0010517 106 57 1,000 0,06733227 0,12053678 ! adult behavior GO:0030534 99 58 1,000 0,06940577 0,12415635 ! positive regulation of lipase activity GO:0060193 108 58 1,000 0,06940577 0,12406411 ! DNA catabolic process GO:0006308 86 59 1,000 0,07150007 0,12771283 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,07194638 0,12841468 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,07194638 0,12831949 ! synapsis GO:0007129 13 10 0,000 0,07194638 0,12822444 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,07194638 0,12812953 ! N-glycan processing GO:0006491 20 10 0,000 0,07194638 0,12803476 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,07194638 0,12794013 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,07194638 0,12784564 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,07194638 0,12775129 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,07194638 0,12765708 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,07194638 0,127563 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,07194638 0,12746907 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,07194638 0,12737527 ! androgen metabolic process GO:0008209 17 10 0,000 0,07194638 0,12728161 ! phospholipid efflux GO:0033700 16 10 0,000 0,07194638 0,12718809 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,07194638 0,12709471 ! lung alveolus development GO:0048286 26 10 0,000 0,07194638 0,12700146 ! pathogenesis GO:0009405 13 10 0,000 0,07194638 0,12690835 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,07194638 0,12681538 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,07194638 0,12672254 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,07194638 0,12662984 ! endoderm development GO:0007492 16 10 0,000 0,07194638 0,12653728 ! arginine catabolic process GO:0006527 13 10 0,000 0,07194638 0,12644485 ! proline metabolic process GO:0006560 13 10 0,000 0,07194638 0,12635255 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,07194638 0,12626039 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,07194638 0,12616836 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,07194638 0,12607647 ! V(D)J recombination GO:0033151 28 10 0,000 0,07194638 0,12598471 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,07194638 0,12589309 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,07194638 0,1258016 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,07194638 0,12571024 ! B cell proliferation GO:0042100 18 10 0,000 0,07194638 0,12561901 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,07194638 0,12552792 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,07194638 0,12543695 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,07194638 0,12534612 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,07194638 0,12525542 ! epithelial cell development GO:0002064 20 10 0,000 0,07194638 0,12516486 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,07194638 0,12507442 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,07194638 0,12498411 ! macroautophagy GO:0016236 17 10 0,000 0,07194638 0,12489394 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,07194638 0,12480389 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,07194638 0,12471397 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,07194638 0,12462419 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,07194638 0,12453453 ! copper ion homeostasis GO:0055070 13 10 0,000 0,07194638 0,124445 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,07194638 0,1243556 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,07194638 0,12426633 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,07194638 0,12417718 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,07194638 0,12408817 ! blastoderm segmentation GO:0007350 18 10 0,000 0,07194638 0,12399928 ! response to dsRNA GO:0043331 20 10 0,000 0,07194638 0,12391052 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,07194638 0,12382188 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,07194638 0,12373338 ! melanosome localization GO:0032400 16 10 0,000 0,07194638 0,123645 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,07194638 0,12355674 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,07194638 0,12346861 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,07194638 0,12338061 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,07194638 0,12329273 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,07194638 0,12320498 ! mRNA cleavage GO:0006379 17 10 0,000 0,07194638 0,12311735 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,07194638 0,12302985 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,07194638 0,12294247 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,07194638 0,12285521 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,07194638 0,12276808 ! prophase GO:0051324 15 10 0,000 0,07194638 0,12268107 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,07194638 0,12259419 ! apical protein localization GO:0045176 15 10 0,000 0,07194638 0,12250743 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,07194638 0,12242079 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,07194638 0,12233427 ! midbrain development GO:0030901 13 10 0,000 0,07194638 0,12224788 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,07194638 0,12216161 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,07194638 0,12207545 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,07194638 0,12198943 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,07194638 0,12190352 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,07194638 0,12181773 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 0,07194638 0,12173206 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 0,07194638 0,12164652 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,07194638 0,12156109 ! cerebellar cortex development GO:0021695 15 10 0,000 0,07194638 0,12147579 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,07194638 0,1213906 ! activation of innate immune response GO:0002218 12 10 0,000 0,07194638 0,12130553 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,07194638 0,12122058 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,07194638 0,12113576 ! response to nicotine GO:0035094 20 10 0,000 0,07194638 0,12105105 ! establishment of cell polarity GO:0030010 16 10 0,000 0,07194638 0,12096645 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,07194638 0,12088198 ! DNA damage response, signal transduction GO:0042770 128 60 1,000 0,07361475 0,1235988 ! regulation of heart contraction GO:0008016 110 60 1,000 0,07361475 0,12351261 ! negative regulation of response to stimulus GO:0048585 100 60 1,000 0,07361475 0,12342654 ! kidney development GO:0001822 122 60 1,000 0,07361475 0,12334059 ! response to peptide hormone stimulus GO:0043434 122 61 1,000 0,07574938 0,12682882 ! viral reproductive process GO:0022415 126 62 1,000 0,07790356 0,1303449 ! gonad development GO:0008406 98 62 1,000 0,07790356 0,13025432 ! respiratory burst GO:0045730 17 11 0,000 0,07885122 0,13174725 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,07885122 0,13165582 ! neuron fate specification GO:0048665 17 11 0,000 0,07885122 0,13156452 ! telencephalon cell migration GO:0022029 20 11 0,000 0,07885122 0,13147335 ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,07885122 0,1313823 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,07885122 0,13129138 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,07885122 0,13120058 ! response to pain GO:0048265 24 11 0,000 0,07885122 0,13110991 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,07885122 0,13101936 ! T cell proliferation GO:0042098 26 11 0,000 0,07885122 0,13092894 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,07885122 0,13083865 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,07885122 0,13074848 ! bone resorption GO:0045453 16 11 0,000 0,07885122 0,13065843 ! ventral spinal cord development GO:0021517 21 11 0,000 0,07885122 0,13056851 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,07885122 0,13047871 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,07885122 0,13038903 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,07885122 0,13029948 ! melanocyte differentiation GO:0030318 21 11 0,000 0,07885122 0,13021005 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,07885122 0,13012074 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,07885122 0,13003156 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,07885122 0,12994249 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,07885122 0,12985355 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,07885122 0,12976473 ! lipid digestion GO:0044241 18 11 0,000 0,07885122 0,12967604 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,07885122 0,12958746 ! UV protection GO:0009650 19 11 0,000 0,07885122 0,129499 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,07885122 0,12941067 ! temperature homeostasis GO:0001659 17 11 0,000 0,07885122 0,12932245 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,07885122 0,12923436 ! negative regulation of ossification GO:0030279 26 11 0,000 0,07885122 0,12914638 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,07885122 0,12905853 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,07885122 0,1289708 ! regulation of organ growth GO:0046620 13 11 0,000 0,07885122 0,12888318 ! pigment granule localization GO:0051875 20 11 0,000 0,07885122 0,12879568 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,07885122 0,1287083 ! vasoconstriction GO:0042310 18 11 0,000 0,07885122 0,12862104 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,07885122 0,1285339 ! embryonic axis specification GO:0000578 18 11 0,000 0,07885122 0,12844688 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,07885122 0,12835997 ! snRNA metabolic process GO:0016073 24 11 0,000 0,07885122 0,12827318 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,07885122 0,12818651 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,07885122 0,12809996 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,07885122 0,12801352 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,07885122 0,1279272 ! zymogen activation GO:0031638 15 11 0,000 0,07885122 0,127841 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,07885122 0,12775491 ! neuroblast proliferation GO:0007405 24 11 0,000 0,07885122 0,12766894 ! nucleosome positioning GO:0016584 15 11 0,000 0,07885122 0,12758308 ! regulation of isotype switching GO:0045191 22 11 0,000 0,07885122 0,12749734 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,07885122 0,12741171 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,07885122 0,1273262 ! acid secretion GO:0046717 18 11 0,000 0,07885122 0,1272408 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,07885122 0,12715552 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,07885122 0,12707035 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,07885122 0,1269853 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,07885122 0,12690036 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,07885122 0,12681553 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! cholesterol efflux GO:0033344 19 11 0,000 0,07885122 0,12673082 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,07885122 0,12664622 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,07885122 0,12656173 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,07885122 0,12647736 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,07885122 0,1263931 ! embryonic gut development GO:0048566 15 11 0,000 0,07885122 0,12630895 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,07885122 0,12622491 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,07885122 0,12614098 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,07885122 0,12605717 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,07885122 0,12597347 ! defense response to fungus GO:0050832 13 11 0,000 0,07885122 0,12588987 ! lysogeny GO:0030069 21 11 0,000 0,07885122 0,12580639 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,07885122 0,12572302 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,07885122 0,12563976 ! sequestering of metal ion GO:0051238 14 11 0,000 0,07885122 0,12555661 ! regulation of embryonic development GO:0045995 27 11 0,000 0,07885122 0,12547357 ! regulation of synapse organization GO:0050807 17 11 0,000 0,07885122 0,12539064 ! cellular amino acid catabolic process GO:0009063 101 63 1,000 0,08007688 0,1272556 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 1,000 0,08226894 0,13065286 ! multicellular organism reproduction GO:0032504 111 64 1,000 0,08226894 0,13056668 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 1,000 0,08226894 0,13048061 ! embryonic limb morphogenesis GO:0030326 125 65 1,000 0,08447935 0,1338981 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 1,000 0,08447935 0,13380996 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,08570492 0,13566186 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,08570492 0,13557267 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,08570492 0,13548359 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 0,08570492 0,13539463 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,08570492 0,13530579 ! virus-host interaction GO:0019048 29 12 0,000 0,08570492 0,13521707 ! cartilage condensation GO:0001502 20 12 0,000 0,08570492 0,13512846 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,08570492 0,13503997 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,08570492 0,13495159 ! protein complex disassembly GO:0043241 27 12 0,000 0,08570492 0,13486333 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,08570492 0,13477518 ! hippocampus development GO:0021766 26 12 0,000 0,08570492 0,13468715 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 0,08570492 0,13459924 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,08570492 0,13451143 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,08570492 0,13442375 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,08570492 0,13433617 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,08570492 0,13424872 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,08570492 0,13416137 ! drug transport GO:0015893 16 12 0,000 0,08570492 0,13407414 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,08570492 0,13398702 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,08570492 0,13390002 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,08570492 0,13381313 ! polyamine metabolic process GO:0006595 17 12 0,000 0,08570492 0,13372635 ! focal adhesion formation GO:0048041 35 12 0,000 0,08570492 0,13363968 ! mitotic spindle organization GO:0007052 21 12 0,000 0,08570492 0,13355313 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,08570492 0,13346669 ! forebrain cell migration GO:0021885 21 12 0,000 0,08570492 0,13338035 ! asymmetric protein localization GO:0008105 20 12 0,000 0,08570492 0,13329414 ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,08570492 0,13320803 ! fear response GO:0042596 26 12 0,000 0,08570492 0,13312203 ! monoamine transport GO:0015844 18 12 0,000 0,08570492 0,13303615 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,08570492 0,13295037 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,08570492 0,13286471 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,08570492 0,13277916 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,08570492 0,13269371 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,08570492 0,13260838 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,08570492 0,13252315 ! protein homotetramerization GO:0051289 21 12 0,000 0,08570492 0,13243804 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,08570492 0,13235303 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,08570492 0,13226814 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,08570492 0,13218335 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,08570492 0,13209867 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,08570492 0,1320141 ! cranial nerve development GO:0021545 20 12 0,000 0,08570492 0,13192964 ! fucose catabolic process GO:0019317 22 12 0,000 0,08570492 0,13184529 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,08570492 0,13176104 ! histone methylation GO:0016571 26 12 0,000 0,08570492 0,1316769 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,08570492 0,13159287 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,08570492 0,13150895 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,08570492 0,13142513 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,08570492 0,13134142 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,08570492 0,13125782 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,08570492 0,13117432 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,08570492 0,13109093 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,08570492 0,13100764 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,08570492 0,13092446 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 0,08570492 0,13084139 GO:0042130|negative regulation of T cell proliferation, ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,08570492 0,13075842 ! response to cold GO:0009409 17 12 0,000 0,08570492 0,13067556 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,08570492 0,1305928 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,08570492 0,13051014 ! actin filament organization GO:0007015 148 66 1,000 0,08670771 0,13195367 ! regulation of cellular response to stress GO:0080135 128 67 1,000 0,08895364 0,13528601 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 1,000 0,08895364 0,13520055 ! hexose catabolic process GO:0019320 104 67 1,000 0,08895364 0,13511519 ! adaptive immune response GO:0002250 119 67 1,000 0,08895364 0,13502995 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! negative regulation of ligase activity GO:0051352 112 68 1,000 0,09121676 0,13837801 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! viral reproduction GO:0016032 134 68 1,000 0,09121676 0,13829081 ! regulation of lipase activity GO:0060191 130 68 1,000 0,09121676 0,13820373 ! cGMP metabolic process GO:0046068 18 13 0,000 0,09250784 0,14007166 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,09250784 0,13998357 ! peroxisomal transport GO:0043574 24 13 0,000 0,09250784 0,13989558 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,09250784 0,13980771 ! lipid localization GO:0010876 28 13 0,000 0,09250784 0,13971994 GO:0019915|lipid storage, ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,09250784 0,13963229 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,09250784 0,13954475 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,09250784 0,13945731 ! endocrine pancreas development GO:0031018 22 13 0,000 0,09250784 0,13936999 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,09250784 0,13928277 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,09250784 0,13919567 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,09250784 0,13910867 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,09250784 0,13902178 ! plasma membrane organization GO:0007009 24 13 0,000 0,09250784 0,138935 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,09250784 0,13884833 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,09250784 0,13876176 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,09250784 0,13867531 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,09250784 0,13858896 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,09250784 0,13850272 ! cytokine metabolic process GO:0042107 22 13 0,000 0,09250784 0,13841659 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 0,09250784 0,13833056 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,09250784 0,13824464 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,09250784 0,13815883 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,09250784 0,13807312 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,09250784 0,13798752 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,09250784 0,13790203 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,09250784 0,13781664 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,09250784 0,13773135 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,09250784 0,13764618 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,09250784 0,13756111 ! regulation of cellular pH GO:0030641 22 13 0,000 0,09250784 0,13747614 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,09250784 0,13739128 ! ribosome assembly GO:0042255 17 13 0,000 0,09250784 0,13730652 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,09250784 0,13722187 ! chromatin silencing GO:0006342 26 13 0,000 0,09250784 0,13713732 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,09250784 0,13705288 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,09250784 0,13696853 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,09250784 0,1368843 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,09250784 0,13680017 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,09250784 0,13671614 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,09250784 0,13663221 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,09250784 0,13654839 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,09250784 0,13646467 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,09250784 0,13638105 ! insulin secretion GO:0030073 23 13 0,000 0,09250784 0,13629753 ! actin filament polymerization GO:0030041 24 13 0,000 0,09250784 0,13621412 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,09250784 0,13613081 ! cell cycle checkpoint GO:0000075 137 69 1,000 0,09349668 0,13750184 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 1,000 0,09349668 0,13741784 ! coenzyme biosynthetic process GO:0009108 102 69 1,000 0,09349668 0,13733395 ! appendage morphogenesis GO:0035107 135 70 1,000 0,09579304 0,14062114 GO:0035108|limb morphogenesis, ! amine catabolic process GO:0009310 117 71 1,000 0,09810547 0,1439279 ! appendage development GO:0048736 136 71 1,000 0,09810547 0,14384019 GO:0060173|limb development, ! rRNA transcription GO:0009303 25 14 0,000 0,09926038 0,14544486 ! lactation GO:0007595 26 14 0,000 0,09926038 0,14535634 ! tRNA modification GO:0006400 20 14 0,000 0,09926038 0,14526792 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,09926038 0,14517961 ! water transport GO:0006833 21 14 0,000 0,09926038 0,14509141 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,09926038 0,14500332 ! non-recombinational repair GO:0000726 25 14 0,000 0,09926038 0,14491533 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,09926038 0,14482745 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,09926038 0,14473967 ! RNA polyadenylation GO:0043631 30 14 0,000 0,09926038 0,14465201 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,09926038 0,14456444 ! regulated secretory pathway GO:0045055 23 14 0,000 0,09926038 0,14447699 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,09926038 0,14438964 ! arginine metabolic process GO:0006525 17 14 0,000 0,09926038 0,14430239 ! regulation of heart rate GO:0002027 24 14 0,000 0,09926038 0,14421526 ! organic alcohol transport GO:0015850 29 14 0,000 0,09926038 0,14412822 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,09926038 0,14404129 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,09926038 0,14395447 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,09926038 0,14386775 GO:0060675|ureteric bud morphogenesis, ! neutral amino acid transport GO:0015804 26 14 0,000 0,09926038 0,14378113 ! L-amino acid transport GO:0015807 30 14 0,000 0,09926038 0,14369462 ! bone mineralization GO:0030282 17 14 0,000 0,09926038 0,14360822 ! stem cell development GO:0048864 43 14 0,000 0,09926038 0,14352191 GO:0019827|stem cell maintenance, ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,09926038 0,14343571 ! cerebellum development GO:0021549 21 14 0,000 0,09926038 0,14334962 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,09926038 0,14326362 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,09926038 0,14317774 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,09926038 0,14309195 ! cofactor transport GO:0051181 26 14 0,000 0,09926038 0,14300627 ! NADP metabolic process GO:0006739 24 14 0,000 0,09926038 0,14292068 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,09926038 0,14283521 ! intestinal absorption GO:0050892 25 14 0,000 0,09926038 0,14274983 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,09926038 0,14266455 ! oxygen transport GO:0015671 21 14 0,000 0,09926038 0,14257938 ! male genitalia development GO:0030539 24 14 0,000 0,09926038 0,14249431 ! regulation of RNA stability GO:0043487 32 14 0,000 0,09926038 0,14240934 ! regulation of axon extension GO:0030516 37 14 0,000 0,09926038 0,14232447 ! release of cytochrome c from mitochondria GO:0001836 30 14 0,000 0,09926038 0,1422397 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,09926038 0,14215504 ! phosphoinositide metabolic process GO:0030384 128 72 1,000 0,1004336 0,1437497 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 1,000 0,1004336 0,14366423 ! fertilization GO:0009566 90 73 1,000 0,10277708 0,14692908 ! leukocyte mediated immunity GO:0002443 128 74 1,000 0,10513555 0,15021147 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,10596289 0,15130368 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,10596289 0,15121394 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! superoxide anion generation GO:0042554 20 15 0,000 0,10596289 0,15112431 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,10596289 0,15103478 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,10596289 0,15094535 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,10596289 0,15085604 ! copper ion transport GO:0006825 20 15 0,000 0,10596289 0,15076683 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,10596289 0,15067772 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,10596289 0,15058872 ! sulfate transport GO:0008272 23 15 0,000 0,10596289 0,15049982 ! response to cAMP GO:0051591 22 15 0,000 0,10596289 0,15041103 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,10596289 0,15032235 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,10596289 0,15023377 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,10596289 0,15014529 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,10596289 0,15005692 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,10596289 0,14996865 ! response to hexose stimulus GO:0009746 22 15 0,000 0,10596289 0,14988048 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,10596289 0,14979242 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,10596289 0,14970446 ! pituitary gland development GO:0021983 29 15 0,000 0,10596289 0,14961661 ! vesicle coating GO:0006901 33 15 0,000 0,10596289 0,14952886 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,10596289 0,14944121 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,10596289 0,14935366 ! regulation of exocytosis GO:0017157 22 15 0,000 0,10596289 0,14926622 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,10596289 0,14917888 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,10596289 0,14909164 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,10596289 0,1490045 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,10596289 0,14891747 ! regulation of vasodilation GO:0042312 26 15 0,000 0,10596289 0,14883053 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,10596289 0,1487437 ! histone deacetylation GO:0016575 20 15 0,000 0,10596289 0,14865697 ! mRNA splice site selection GO:0006376 38 15 0,000 0,10596289 0,14857034 ! tissue regeneration GO:0042246 26 15 0,000 0,10596289 0,14848381 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,10596289 0,14839738 ! water homeostasis GO:0030104 27 15 0,000 0,10596289 0,14831105 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,10596289 0,14822483 ! muscle maintenance GO:0046716 26 15 0,000 0,10596289 0,1481387 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,10596289 0,14805267 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,10596289 0,14796675 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,10596289 0,14788092 ! heme biosynthetic process GO:0006783 29 15 0,000 0,10596289 0,14779519 ! cell killing GO:0001906 29 15 0,000 0,10596289 0,14770956 ! detection of bacterium GO:0016045 18 15 0,000 0,10596289 0,14762403 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,10596289 0,1475386 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,10596289 0,14745327 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,10596289 0,14736804 ! peptide hormone processing GO:0016486 23 15 0,000 0,10596289 0,1472829 ! phosphoinositide-mediated signaling GO:0048015 131 75 1,000 0,10750866 0,14934517 ! rhythmic process GO:0048511 128 75 1,000 0,10750866 0,14925899 ! development of primary sexual characteristics GO:0045137 124 76 1,000 0,10989606 0,15248554 ! monosaccharide catabolic process GO:0046365 115 76 1,000 0,10989606 0,15239765 ! positive regulation of ligase activity GO:0051351 124 77 1,000 0,11229742 0,15563802 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,11261574 0,15598934 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,11261574 0,15589958 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,11261574 0,15580994 ! bone remodeling GO:0046849 27 16 0,000 0,11261574 0,15572039 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,11261574 0,15563095 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,11261574 0,15554161 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,11261574 0,15545237 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,11261574 0,15536323 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,11261574 0,1552742 ! protein polyubiquitination GO:0000209 34 16 0,000 0,11261574 0,15518527 ! glutamate metabolic process GO:0006536 22 16 0,000 0,11261574 0,15509644 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,11261574 0,15500771 ! response to osmotic stress GO:0006970 25 16 0,000 0,11261574 0,15491908 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,11261574 0,15483056 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,11261574 0,15474213 ! fructose metabolic process GO:0006000 25 16 0,000 0,11261574 0,15465381 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,11261574 0,15456559 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 32 16 0,000 0,11261574 0,15447747 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,11261574 0,15438945 ! axon cargo transport GO:0008088 43 16 0,000 0,11261574 0,15430153 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,11261574 0,1542137 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,11261574 0,15412598 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 0,11261574 0,15403836 ! DNA replication initiation GO:0006270 27 16 0,000 0,11261574 0,15395084 ! neuron recognition GO:0008038 35 16 0,000 0,11261574 0,15386342 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,11261574 0,15377609 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,11261574 0,15368887 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,11261574 0,15360175 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,11261574 0,15351472 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,11261574 0,15342779 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,11261574 0,15334096 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,11261574 0,15325423 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,11261574 0,1531676 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,11261574 0,15308106 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 0,11261574 0,15299462 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! defense response to virus GO:0051607 37 16 0,000 0,11261574 0,15290828 ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 1,000 0,1147124 0,15566725 ! protein oligomerization GO:0051259 139 78 1,000 0,1147124 0,1555795 ! regulation of synaptic transmission GO:0050804 134 79 1,000 0,11714066 0,15878334 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,11921931 0,16150995 ! metencephalon development GO:0022037 30 17 0,000 0,11921931 0,16141906 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,11921931 0,16132827 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,11921931 0,16123759 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,11921931 0,161147 ! endothelial cell migration GO:0043542 28 17 0,000 0,11921931 0,16105652 ! inositol metabolic process GO:0006020 28 17 0,000 0,11921931 0,16096614 ! gene silencing by RNA GO:0031047 36 17 0,000 0,11921931 0,16087587 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,11921931 0,16078569 ! limbic system development GO:0021761 36 17 0,000 0,11921931 0,16069561 ! adult walking behavior GO:0007628 33 17 0,000 0,11921931 0,16060564 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,11921931 0,16051576 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,11921931 0,16042599 ! myoblast differentiation GO:0045445 45 17 0,000 0,11921931 0,16033632 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,11921931 0,16024674 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,11921931 0,16015727 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,11921931 0,1600679 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,11921931 0,15997862 ! glycine metabolic process GO:0006544 28 17 0,000 0,11921931 0,15988945 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,11921931 0,15980037 ! NAD metabolic process GO:0019674 29 17 0,000 0,11921931 0,1597114 ! membrane budding GO:0006900 37 17 0,000 0,11921931 0,15962252 ! DNA integration GO:0015074 29 17 0,000 0,11921931 0,15953374 ! regulation of protein binding GO:0043393 33 17 0,000 0,11921931 0,15944506 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,11921931 0,15935648 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,11921931 0,159268 ! genitalia development GO:0048806 30 17 0,000 0,11921931 0,15917962 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,11921931 0,15909133 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,11921931 0,15900314 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,11921931 0,15891505 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,11921931 0,15882706 ! steroid catabolic process GO:0006706 31 17 0,000 0,11921931 0,15873916 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,11921931 0,15865137 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,11921931 0,15856366 ! gas transport GO:0015669 25 17 0,000 0,11921931 0,15847606 ! organic cation transport GO:0015695 31 17 0,000 0,11921931 0,15838855 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,11921931 0,15830114 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,11921931 0,15821383 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,11921931 0,15812661 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,11921931 0,15803949 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,11921931 0,15795246 ! regulation of adenylate cyclase activity GO:0045761 156 80 1,000 0,11958188 0,15834563 ! response to metal ion GO:0010038 140 80 1,000 0,11958188 0,15825853 ! protein import into nucleus GO:0006606 158 80 1,000 0,11958188 0,15817152 ! nuclear import GO:0051170 161 81 1,000 0,12203573 0,16132855 ! regulation of cAMP biosynthetic process GO:0030817 161 82 1,000 0,12450188 0,16449837 ! response to nutrient GO:0007584 125 82 1,000 0,12450188 0,16440808 ! regulation of cyclase activity GO:0031279 159 82 1,000 0,12450188 0,1643179 ! cellular response to hormone stimulus GO:0032870 167 82 1,000 0,12450188 0,16422781 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,12577396 0,16581488 ! neuron maturation GO:0042551 42 18 0,000 0,12577396 0,16572407 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,12577396 0,16563336 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,12577396 0,16554275 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,12577396 0,16545224 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,12577396 0,16536183 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,12577396 0,16527152 ! memory GO:0007613 31 18 0,000 0,12577396 0,1651813 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,12577396 0,16509119 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,12577396 0,16500117 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,12577396 0,16491125 ! glutamine metabolic process GO:0006541 29 18 0,000 0,12577396 0,16482143 ! response to retinoic acid GO:0032526 26 18 0,000 0,12577396 0,16473171 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,12577396 0,16464208 ! response to fungus GO:0009620 21 18 0,000 0,12577396 0,16455256 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,12577396 0,16446312 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,12577396 0,16437379 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,12577396 0,16428455 ! vitamin transport GO:0051180 27 18 0,000 0,12577396 0,16419541 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,12577396 0,16410637 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,12577396 0,16401743 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,12577396 0,16392857 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,12577396 0,16383982 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,12577396 0,16375116 ! nerve development GO:0021675 28 18 0,000 0,12577396 0,1636626 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,12577396 0,16357413 ! regulation of lyase activity GO:0051339 160 83 1,000 0,12698003 0,16505346 ! regulation of cAMP metabolic process GO:0030814 168 84 1,000 0,12946986 0,16819897 ! regulation of transmission of nerve impulse GO:0051969 141 84 1,000 0,12946986 0,1681082 ! one-carbon metabolic process GO:0006730 154 85 1,000 0,13197106 0,17126342 ! protein secretion GO:0009306 39 19 0,000 0,13228004 0,17157185 ! positive regulation of translation GO:0045727 30 19 0,000 0,13228004 0,17147941 ! negative regulation of defense response GO:0031348 25 19 0,000 0,13228004 0,17138707 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,13228004 0,17129483 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,13228004 0,17120268 ! skin development GO:0043588 36 19 0,000 0,13228004 0,17111064 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,13228004 0,17101869 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,13228004 0,17092685 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,13228004 0,1708351 ! bile acid metabolic process GO:0008206 29 19 0,000 0,13228004 0,17074345 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,13228004 0,1706519 ! pigmentation during development GO:0048066 41 19 0,000 0,13228004 0,17056044 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,13228004 0,17046909 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,13228004 0,17037783 ! heme metabolic process GO:0042168 36 19 0,000 0,13228004 0,17028667 ! actin filament bundle formation GO:0051017 42 19 0,000 0,13228004 0,17019561 ! neuromuscular junction development GO:0007528 34 19 0,000 0,13228004 0,17010464 ! plasma membrane fusion GO:0045026 28 19 0,000 0,13228004 0,17001378 ! peptide cross-linking GO:0018149 37 19 0,000 0,13228004 0,169923 ! protein export from nucleus GO:0006611 36 19 0,000 0,13228004 0,16983233 ! heart process GO:0003015 30 19 0,000 0,13228004 0,16974175 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,13228004 0,16965127 GO:0006692|prostanoid metabolic process, ! cellular pigmentation GO:0033059 36 19 0,000 0,13228004 0,16956089 ! G1 phase GO:0051318 40 19 0,000 0,13228004 0,1694706 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,13228004 0,16938041 ! cell-cell junction organization GO:0045216 35 19 0,000 0,13228004 0,16929031 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,13228004 0,16920031 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,13228004 0,16911041 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,13228004 0,1690206 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,13228004 0,16893089 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,13228004 0,16884127 ! cilium assembly GO:0042384 37 19 0,000 0,13228004 0,16875174 ! peptide hormone secretion GO:0030072 31 19 0,000 0,13228004 0,16866231 ! response to inorganic substance GO:0010035 153 86 1,000 0,13448333 0,17138077 ! alcohol catabolic process GO:0046164 130 86 1,000 0,13448333 0,17129005 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 1,000 0,13700637 0,17441128 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 1,000 0,13700637 0,17431905 ! protein localization in nucleus GO:0034504 176 87 1,000 0,13700637 0,17422691 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,13873792 0,17633568 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,13873792 0,17624258 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,13873792 0,17614958 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,13873792 0,17605667 ! cAMP metabolic process GO:0046058 36 20 0,000 0,13873792 0,17596386 ! response to vitamin GO:0033273 31 20 0,000 0,13873792 0,17587115 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,13873792 0,17577854 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 0,13873792 0,17568602 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,13873792 0,17559361 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,13873792 0,17550129 ! response to alkaloid GO:0043279 38 20 0,000 0,13873792 0,17540906 ! retinoid metabolic process GO:0001523 32 20 0,000 0,13873792 0,17531694 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,13873792 0,17522491 ! apoptotic mitochondrial changes GO:0008637 41 20 0,000 0,13873792 0,17513297 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,13873792 0,17504114 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,13873792 0,1749494 ! cellular response to starvation GO:0009267 33 20 0,000 0,13873792 0,17485775 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,13873792 0,1747662 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,13873792 0,17467475 ! body fluid secretion GO:0007589 31 20 0,000 0,13873792 0,17458339 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,13873792 0,17449213 ! peptide secretion GO:0002790 35 20 0,000 0,13873792 0,17440097 ! stem cell differentiation GO:0048863 53 20 0,000 0,13873792 0,17430989 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,13873792 0,17421892 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,13873792 0,17412804 ! sensory perception of pain GO:0019233 30 20 0,000 0,13873792 0,17403725 ! diencephalon development GO:0021536 34 20 0,000 0,13873792 0,17394656 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,13873792 0,17385596 GO:0006626|protein targeting to mitochondrion, ! detection of chemical stimulus GO:0009593 37 20 0,000 0,13873792 0,17376546 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,13873792 0,17367505 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,13873792 0,17358474 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,13873792 0,17349452 ! regulation of glucose import GO:0046324 29 20 0,000 0,13873792 0,17340439 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,13873792 0,17331435 ! actin filament-based movement GO:0030048 43 20 0,000 0,13873792 0,17322441 ! negative regulation of T cell activation GO:0050868 40 20 0,000 0,13873792 0,17313457 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,13873792 0,17304481 ! negative regulation of translation GO:0017148 29 20 0,000 0,13873792 0,17295515 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,13873792 0,17286559 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,13873792 0,17277611 ! cellular respiration GO:0045333 135 88 1,000 0,13953987 0,17368491 ! regulation of cell morphogenesis GO:0022604 215 89 1,000 0,14208355 0,17675958 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 1,000 0,14463712 0,17984336 ! regulation of cell killing GO:0031341 42 21 0,000 0,14514796 0,18038532 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,14514796 0,1802922 ! hormone secretion GO:0046879 38 21 0,000 0,14514796 0,18019917 ! glycerol metabolic process GO:0006071 34 21 0,000 0,14514796 0,18010623 ! axis specification GO:0009798 38 21 0,000 0,14514796 0,18001339 ! ovarian follicle development GO:0001541 35 21 0,000 0,14514796 0,17992065 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,14514796 0,179828 ! smooth muscle contraction GO:0006939 46 21 0,000 0,14514796 0,17973545 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,14514796 0,17964299 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,14514796 0,17955063 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,14514796 0,17945837 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,14514796 0,1793662 ! cytolysis GO:0019835 24 21 0,000 0,14514796 0,17927412 ! vasodilation GO:0042311 39 21 0,000 0,14514796 0,17918214 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,14514796 0,17909025 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,14514796 0,17899845 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,14514796 0,17890675 ! DNA modification GO:0006304 34 21 0,000 0,14514796 0,17881515 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,14514796 0,17872363 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,14514796 0,17863222 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,14514796 0,17854089 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,14514796 0,17844966 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,14514796 0,17835852 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,14514796 0,17826747 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,14514796 0,17817652 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,14514796 0,17808566 ! collagen catabolic process GO:0030574 28 21 0,000 0,14514796 0,17799489 ! sperm-egg recognition GO:0035036 21 21 0,000 0,14514796 0,17790422 ! gut development GO:0048565 39 21 0,000 0,14514796 0,17781364 ! cofactor biosynthetic process GO:0051188 139 91 1,000 0,14720028 0,18023607 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,15151049 0,18541925 ! microtubule-based transport GO:0010970 54 22 0,000 0,15151049 0,18532498 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,15151049 0,18523081 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,15151049 0,18513674 ! regeneration GO:0031099 41 22 0,000 0,15151049 0,18504276 ! keratinization GO:0031424 28 22 0,000 0,15151049 0,18494888 ! sensory perception of taste GO:0050909 28 22 0,000 0,15151049 0,18485509 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,15151049 0,1847614 ! vacuolar transport GO:0007034 36 22 0,000 0,15151049 0,1846678 ! lysosome organization GO:0007040 41 22 0,000 0,15151049 0,1845743 ! central nervous system neuron development GO:0021954 46 22 0,000 0,15151049 0,18448089 ! fucose metabolic process GO:0006004 39 22 0,000 0,15151049 0,18438758 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,15151049 0,18429436 ! ureteric bud development GO:0001657 43 22 0,000 0,15151049 0,18420123 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,15151049 0,1841082 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,15151049 0,18401527 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,15151049 0,18392242 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,15151049 0,18382967 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,15151049 0,18373702 ! sarcomere organization GO:0045214 30 22 0,000 0,15151049 0,18364445 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,15151049 0,18355198 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,15151049 0,18345961 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,15151049 0,18336732 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,15151049 0,18327513 ! positive regulation of MAP kinase activity GO:0043406 160 93 1,000 0,15235429 0,18420322 ! regulation of nucleotide metabolic process GO:0006140 182 93 1,000 0,15235429 0,18411071 ! regulation of membrane potential GO:0042391 164 93 1,000 0,15235429 0,18401828 ! negative regulation of multicellular organismal process GO:0051241 166 93 1,000 0,15235429 0,18392595 ! transcription initiation GO:0006352 153 94 1,000 0,15494457 0,1869592 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,15782588 0,19034039 ! gluconeogenesis GO:0006094 33 23 0,000 0,15782588 0,19024502 ! viral genome replication GO:0019079 41 23 0,000 0,15782588 0,19014976 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,15782588 0,19005459 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,15782588 0,18995951 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,15782588 0,18986453 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,15782588 0,18976965 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,15782588 0,18967486 ! regulation of DNA recombination GO:0000018 48 23 0,000 0,15782588 0,18958016 ! response to ethanol GO:0045471 46 23 0,000 0,15782588 0,18948556 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,15782588 0,18939106 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,15782588 0,18929664 ! peroxisome organization GO:0007031 37 23 0,000 0,15782588 0,18920233 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,15782588 0,1891081 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,15782588 0,18901397 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,15782588 0,18891993 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,15782588 0,18882599 GO:0051693|actin filament capping, ! sex determination GO:0007530 47 23 0,000 0,15782588 0,18873214 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,15782588 0,18863838 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,15782588 0,18854472 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,15782588 0,18845115 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,15782588 0,18835767 ! fatty acid transport GO:0015908 44 23 0,000 0,15782588 0,18826429 ! platelet activation GO:0030168 37 23 0,000 0,15782588 0,188171 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,15782588 0,1880778 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,15782588 0,18798469 ! hormone transport GO:0009914 40 23 0,000 0,15782588 0,18789167 ! cell-cell recognition GO:0009988 25 23 0,000 0,15782588 0,18779875 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,15782588 0,18770592 ! positive regulation of immune response GO:0050778 156 96 1,000 0,16015036 0,19037637 ! protein ubiquitination GO:0016567 217 97 1,000 0,16276533 0,19338932 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,16409447 0,19487231 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,16409447 0,19477617 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,16409447 0,19468013 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,16409447 0,19458418 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,16409447 0,19448833 ! vesicle docking GO:0048278 47 24 0,000 0,16409447 0,19439257 ! vacuole organization GO:0007033 43 24 0,000 0,16409447 0,1942969 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,16409447 0,19420133 ! digestive system process GO:0022600 39 24 0,000 0,16409447 0,19410585 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,16409447 0,19401047 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,16409447 0,19391518 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,16409447 0,19381998 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,16409447 0,19372488 ! membrane depolarization GO:0051899 39 24 0,000 0,16409447 0,19362987 ! pentose metabolic process GO:0019321 35 24 0,000 0,16409447 0,19353495 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,16409447 0,19344013 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,16409447 0,1933454 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,16409447 0,19325076 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,16409447 0,19315621 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,16409447 0,19306176 ! regulation of amine transport GO:0051952 40 24 0,000 0,16409447 0,1929674 ! protein tetramerization GO:0051262 52 24 0,000 0,16409447 0,19287313 ! carboxylic acid catabolic process GO:0046395 156 98 1,000 0,165388 0,19429859 GO:0016054|organic acid catabolic process, ! skeletal muscle tissue development GO:0007519 186 99 1,000 0,1680181 0,19729212 GO:0060538|skeletal muscle organ development, ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,17031661 0,19989355 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,17031661 0,19979608 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,17031661 0,19969872 ! phototransduction GO:0007602 33 25 0,000 0,17031661 0,19960145 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,17031661 0,19950427 GO:0006479|protein amino acid methylation, ! sperm motility GO:0030317 31 25 0,000 0,17031661 0,19940719 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,17031661 0,1993102 ! receptor metabolic process GO:0043112 46 25 0,000 0,17031661 0,1992133 ! response to starvation GO:0042594 42 25 0,000 0,17031661 0,19911651 ! neural crest cell development GO:0014032 54 25 0,000 0,17031661 0,1990198 GO:0014033|neural crest cell differentiation, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,17031661 0,19892319 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,17031661 0,19882667 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,17031661 0,19873025 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! immunoglobulin production GO:0002377 55 25 0,000 0,17031661 0,19863392 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,17031661 0,19853768 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,17031661 0,19844153 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,17031661 0,19834548 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,17031661 0,19824952 ! telomere organization GO:0032200 43 25 0,000 0,17031661 0,19815366 GO:0000723|telomere maintenance, ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,17649264 0,20523987 ! embryonic pattern specification GO:0009880 44 26 0,000 0,17649264 0,20514072 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,17649264 0,20504167 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,17649264 0,20494271 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,17649264 0,20484385 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,17649264 0,20474508 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,17649264 0,20464641 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,17649264 0,20454783 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,17649264 0,20444935 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 0,000 0,17649264 0,20435096 ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,17649264 0,20425267 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,17649264 0,20415447 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,17649264 0,20405636 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,17649264 0,20395835 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,17649264 0,20386044 ! leukocyte proliferation GO:0070661 52 26 0,000 0,17649264 0,20376262 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,17649264 0,20366489 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,17649264 0,20356726 ! neuron fate commitment GO:0048663 48 27 0,000 0,1826229 0,21053699 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,1826229 0,21043616 ! iron ion transport GO:0006826 59 27 0,000 0,1826229 0,21033542 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,1826229 0,21023478 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,1826229 0,21013424 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,1826229 0,2100338 ! fat cell differentiation GO:0045444 50 27 0,000 0,1826229 0,20993344 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,1826229 0,20983319 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,1826229 0,20973303 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,1826229 0,20963297 ! autophagy GO:0006914 41 27 0,000 0,1826229 0,209533 ! male gonad development GO:0008584 44 27 0,000 0,1826229 0,20943313 ! response to toxin GO:0009636 47 27 0,000 0,1826229 0,20933335 ! base-excision repair GO:0006284 41 27 0,000 0,1826229 0,20923367 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,1826229 0,20913408 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,1826229 0,20903459 ! glutathione metabolic process GO:0006749 39 27 0,000 0,1826229 0,20893519 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,1826229 0,20883588 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,1826229 0,20873667 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,1826229 0,20863756 ! negative regulation of lymphocyte activation GO:0051250 53 27 0,000 0,1826229 0,20853854 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,18870773 0,21538463 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,18870773 0,2152825 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,18870773 0,21518047 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,18870773 0,21507854 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,18870773 0,2149767 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,18870773 0,21487496 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,18870773 0,21477332 ! peptidyl-tyrosine modification GO:0018212 50 28 0,000 0,18870773 0,21467177 ! lipid oxidation GO:0034440 43 28 0,000 0,18870773 0,21457032 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,18870773 0,21446896 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,18870773 0,2143677 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,19474746 0,2211243 ! regulation of pH GO:0006885 43 29 0,000 0,19474746 0,22101999 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,19474746 0,22091579 ! complement activation, classical pathway GO:0006958 48 29 0,000 0,19474746 0,22081168 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,19474746 0,22070767 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,19474746 0,22060376 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,19474746 0,22049995 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,19474746 0,22039623 ! cell fate determination GO:0001709 60 29 0,000 0,19474746 0,22029261 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,19474746 0,22018909 ! detection of light stimulus GO:0009583 38 29 0,000 0,19474746 0,22008567 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,19474746 0,21998234 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,19474746 0,21987911 ! regulation of coagulation GO:0050818 46 29 0,000 0,19474746 0,21977598 ! zinc ion transport GO:0006829 45 30 0,000 0,20074243 0,2264352 ! membrane docking GO:0022406 61 30 0,000 0,20074243 0,22632909 ! cell junction assembly GO:0034329 78 30 0,000 0,20074243 0,22622308 ! regulation of innate immune response GO:0045088 51 30 0,000 0,20074243 0,22611717 ! acute-phase response GO:0006953 49 30 0,000 0,20074243 0,22601136 ! myofibril assembly GO:0030239 47 30 0,000 0,20074243 0,22590565 GO:0055002|striated muscle cell development, ! determination of left/right symmetry GO:0007368 47 30 0,000 0,20074243 0,22580004 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,20074243 0,22569452 ! phospholipid transport GO:0015914 51 30 0,000 0,20074243 0,22558911 ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,20074243 0,22548379 GO:0046496|nicotinamide nucleotide metabolic process, ! negative regulation of leukocyte activation GO:0002695 56 30 0,000 0,20074243 0,22537857 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,20074243 0,22527345 ! response to heat GO:0009408 50 30 0,000 0,20074243 0,22516843 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,20669296 0,23173498 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,20669296 0,23162704 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,20669296 0,23151921 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,20669296 0,23141148 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,20669296 0,23130384 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,20669296 0,23119631 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,20669296 0,23108888 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,20669296 0,23098154 ! ovulation cycle process GO:0022602 49 31 0,000 0,20669296 0,23087431 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,20669296 0,23076718 ! peptide transport GO:0015833 55 31 0,000 0,20669296 0,23066014 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,20669296 0,2305532 ! mesoderm formation GO:0001707 69 31 0,000 0,20669296 0,23044637 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,20669296 0,23033963 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,20669296 0,23023299 ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,20669296 0,23012645 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,21259939 0,23659303 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,21259939 0,23648365 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,21259939 0,23637437 ! cholesterol transport GO:0030301 56 32 0,000 0,21259939 0,23626519 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,21259939 0,23615611 ! spliceosome assembly GO:0000245 67 32 0,000 0,21259939 0,23604713 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,21259939 0,23593825 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,21259939 0,23582947 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,21259939 0,2357208 ! muscle cell development GO:0055001 49 32 0,000 0,21259939 0,23561222 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,21259939 0,23550374 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,21259939 0,23539536 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,21259939 0,23528709 ! ovulation cycle GO:0042698 51 32 0,000 0,21259939 0,23517891 ! BMP signaling pathway GO:0030509 64 32 0,000 0,21259939 0,23507083 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,21259939 0,23496285 ! gene silencing GO:0016458 65 32 0,000 0,21259939 0,23485497 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,21846204 0,24122059 ! post-embryonic development GO:0009791 69 33 0,000 0,21846204 0,24110993 ! protein targeting to membrane GO:0006612 68 33 0,000 0,21846204 0,24099938 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,21846204 0,24088894 ! ceramide metabolic process GO:0006672 64 33 0,000 0,21846204 0,24077859 ! formation of primary germ layer GO:0001704 72 33 0,000 0,21846204 0,24066834 ! sterol transport GO:0015918 57 33 0,000 0,21846204 0,2405582 ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,21846204 0,24044815 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,21846204 0,24033821 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,22428122 0,24662734 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,22428122 0,24651468 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,22428122 0,24640211 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,22428122 0,24628965 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,22428122 0,24617729 ! mismatch repair GO:0006298 46 34 0,000 0,22428122 0,24606504 ! spermatid development GO:0007286 63 34 0,000 0,22428122 0,24595288 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,22428122 0,24584083 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,23005728 0,25205729 ! negative regulation of secretion GO:0051048 63 35 0,000 0,23005728 0,25194256 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,23005728 0,25182794 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,23005728 0,25171342 ! odontogenesis GO:0042476 66 35 0,000 0,23005728 0,251599 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,23005728 0,25148469 GO:0006639|acylglycerol metabolic process, ! cytokine production GO:0001816 59 35 0,000 0,23005728 0,25137049 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,23005728 0,25125638 ! vesicle localization GO:0051648 64 35 0,000 0,23005728 0,25114238 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,23579051 0,25728434 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,23579051 0,25716771 ! cell junction organization GO:0034330 86 36 0,000 0,23579051 0,25705119 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,23579051 0,25693477 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,23579051 0,25681846 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,23579051 0,25670225 ! regulation of proteolysis GO:0030162 72 36 0,000 0,23579051 0,25658615 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,23579051 0,25647015 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,23579051 0,25635426 ! negative regulation of cell activation GO:0050866 65 36 0,000 0,23579051 0,25623847 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,24148125 0,26230423 ! actomyosin structure organization GO:0031032 62 37 0,000 0,24148125 0,26218586 ! organic anion transport GO:0015711 68 37 0,000 0,24148125 0,2620676 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,24148125 0,26194945 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,24148125 0,2618314 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,24148125 0,26171346 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,24148125 0,26159562 GO:0015986|ATP synthesis coupled proton transport, ! pigment metabolic process GO:0042440 80 37 0,000 0,24148125 0,26147789 ! spermatid differentiation GO:0048515 66 37 0,000 0,24148125 0,26136027 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,24712979 0,26735354 GO:0006956|complement activation, ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,24712979 0,26723338 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,24712979 0,26711333 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,24712979 0,26699339 ! carbohydrate homeostasis GO:0033500 53 38 0,000 0,24712979 0,26687355 GO:0042593|glucose homeostasis, ! lipid homeostasis GO:0055088 67 38 0,000 0,24712979 0,26675382 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,24712979 0,2666342 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,24712979 0,26651469 ! mRNA catabolic process GO:0006402 71 39 0,000 0,25273646 0,27243903 ! ear morphogenesis GO:0042471 60 39 0,000 0,25273646 0,27231702 ! organic ether metabolic process GO:0018904 55 39 0,000 0,25273646 0,27219513 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,25273646 0,27207334 ! ion transmembrane transport GO:0034220 66 39 0,000 0,25273646 0,27195166 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,25273646 0,27183009 ! RNA modification GO:0009451 57 39 0,000 0,25273646 0,27170863 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,25273646 0,27158728 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,25830155 0,27744354 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,25830155 0,27731974 ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,25830155 0,27719605 ! maintenance of protein location GO:0045185 91 40 0,000 0,25830155 0,27707247 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,26382539 0,28287161 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,26382539 0,28274561 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,26382539 0,28261972 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,26382539 0,28249394 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,26382539 0,28236828 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,26382539 0,28224273 ! polyol metabolic process GO:0019751 66 41 0,000 0,26382539 0,28211729 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,26382539 0,28199196 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,26930827 0,28772456 ! regulation of tube size GO:0035150 71 42 0,000 0,26930827 0,28759685 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,26930827 0,28746926 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,26930827 0,28734177 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,26930827 0,28721441 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,26930827 0,28708715 ! regulation of protein secretion GO:0050708 71 42 0,000 0,26930827 0,28696001 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,2747505 0,29262935 ! glucose transport GO:0015758 65 43 0,000 0,2747505 0,29249987 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,2747505 0,2923705 ! striated muscle contraction GO:0006941 77 43 0,000 0,2747505 0,29224125 ! phagocytosis GO:0006909 90 43 0,000 0,2747505 0,29211211 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,28015237 0,29772376 ! hexose transport GO:0008645 67 44 0,000 0,28015237 0,29759232 GO:0015749|monosaccharide transport, ! male sex differentiation GO:0046661 76 44 0,000 0,28015237 0,29746099 ! biopolymer methylation GO:0043414 84 44 0,000 0,28015237 0,29732978 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,28015237 0,29719868 ! maintenance of location in cell GO:0051651 97 44 0,000 0,28015237 0,2970677 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,28551418 0,30261988 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,28551418 0,30248663 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,28551418 0,30235349 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,28551418 0,30222047 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,28551418 0,30208757 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,28551418 0,30195478 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,29083624 0,30744815 ! positive regulation of defense response GO:0031349 76 47 0,000 0,29611883 0,31289499 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,29611883 0,31275764 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,29611883 0,3126204 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,29611883 0,31248329 ! methylation GO:0032259 90 47 0,000 0,29611883 0,31234629 ! mitochondrial transport GO:0006839 82 48 0,000 0,30136224 0,31773775 ! cellular component disassembly GO:0022411 86 48 0,000 0,30136224 0,31759857 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,30136224 0,31745952 ! activation of caspase activity GO:0006919 84 48 0,000 0,30136224 0,31732059 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,30136224 0,31718178 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,30656676 0,32251842 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,30656676 0,32237746 ! regulation of ion transport GO:0043269 77 49 0,000 0,30656676 0,32223662 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,30656676 0,32209591 ! peptide metabolic process GO:0006518 76 49 0,000 0,30656676 0,32195532 ! response to temperature stimulus GO:0009266 76 49 0,000 0,30656676 0,32181485 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,30656676 0,3216745 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,30656676 0,32153428 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,30656676 0,32139418 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,30656676 0,3212542 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,31173269 0,3265254 ! excretion GO:0007588 83 51 0,000 0,3168603 0,33175191 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,3168603 0,3316076 ! regulation of cell shape GO:0008360 125 51 0,000 0,3168603 0,33146343 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,32194988 0,3366412 ! amino acid activation GO:0043038 92 52 0,000 0,32194988 0,33649496 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 76 53 0,000 0,32700171 0,34162662 ! RNA catabolic process GO:0006401 93 53 0,000 0,32700171 0,34147835 ! regulation of translational initiation GO:0006446 82 53 0,000 0,32700171 0,3413302 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,32700171 0,34118218 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,32700171 0,34103429 ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,33201606 0,3461138 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,33201606 0,3459639 ! cell recognition GO:0008037 85 54 0,000 0,33201606 0,34581413 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,33201606 0,3456645 ! chloride transport GO:0006821 90 55 0,000 0,33699323 0,35069451 ! positive regulation of caspase activity GO:0043280 95 55 0,000 0,33699323 0,35054289 GO:0010952|positive regulation of peptidase activity, ! gastrulation GO:0007369 112 55 0,000 0,33699323 0,3503914 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,33699323 0,35024004 ! sensory perception of smell GO:0007608 80 56 0,000 0,34193347 0,35522104 ! skeletal muscle fiber development GO:0048741 111 56 0,000 0,34193347 0,35506773 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,34193347 0,35491455 ! proton transport GO:0015992 94 56 0,000 0,34193347 0,3547615 ! muscle fiber development GO:0048747 112 57 0,000 0,34683706 0,35969395 ! maintenance of location GO:0051235 118 57 0,000 0,34683706 0,35953898 ! hydrogen transport GO:0006818 97 58 0,000 0,35170427 0,36442743 ! regulation of endocytosis GO:0030100 91 58 0,000 0,35170427 0,36427055 ! positive regulation of secretion GO:0051047 95 59 0,000 0,35653538 0,36911537 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,35653538 0,36895661 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,35653538 0,36879799 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,35653538 0,3686395 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,36133065 0,37343709 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,36133065 0,37327674 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,36609033 0,37803148 ! mesoderm development GO:0007498 119 61 0,000 0,36609033 0,3778693 ! tRNA processing GO:0008033 89 61 0,000 0,36609033 0,37770727 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,36609033 0,37754537 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,37081471 0,38225372 ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,37550403 0,38692192 ! detection of external stimulus GO:0009581 91 63 0,000 0,37550403 0,38675629 ! cell redox homeostasis GO:0045454 102 64 0,000 0,38015855 0,39138275 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,38015855 0,39121535 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,38477854 0,39580041 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,38477854 0,39563127 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,38936424 0,4001753 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,38936424 0,40000443 ! secondary metabolic process GO:0019748 116 66 0,000 0,38936424 0,39983371 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,39391592 0,4043352 ! activation of MAPK activity GO:0000187 115 67 0,000 0,39391592 0,40416277 ! activation of immune response GO:0002253 105 67 0,000 0,39391592 0,4039905 ! amino acid transport GO:0006865 125 68 0,000 0,39843382 0,40844984 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,39843382 0,40827588 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,39843382 0,40810207 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,40291819 0,41251964 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,40291819 0,41234418 ! antigen processing and presentation GO:0019882 104 69 0,000 0,40291819 0,41216886 ! humoral immune response GO:0006959 109 71 0,000 0,41178733 0,42106261 ! regulation of immune effector process GO:0002697 137 71 0,000 0,41178733 0,42088374 ! acute inflammatory response GO:0002526 113 72 0,000 0,4161726 0,42518525 ! regulation of caspase activity GO:0043281 122 72 0,000 0,4161726 0,42500478 ! carbohydrate transport GO:0008643 110 72 0,000 0,4161726 0,42482447 ! regulation of blood pressure GO:0008217 125 73 0,000 0,42052531 0,42908562 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,42052531 0,42890373 ! axon guidance GO:0007411 139 73 0,000 0,42052531 0,42872199 ! transition metal ion transport GO:0000041 126 74 0,000 0,42484572 0,43294316 ! neurotransmitter transport GO:0006836 123 74 0,000 0,42484572 0,43275986 ! exocytosis GO:0006887 133 74 0,000 0,42484572 0,43257672 ! regulation of endopeptidase activity GO:0052548 125 74 0,000 0,42484572 0,43239374 ! cell-matrix adhesion GO:0007160 163 75 0,000 0,42913406 0,43657359 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,42913406 0,43638907 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,42913406 0,43620471 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,43339056 0,44034531 ! defense response to bacterium GO:0042742 89 76 0,000 0,43339056 0,44015943 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,43339056 0,43997371 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,43761547 0,44407542 ! blood coagulation GO:0007596 146 78 0,000 0,44180902 0,44814186 GO:0050817|coagulation, ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,44597144 0,45217331 ! regulation of peptidase activity GO:0052547 134 79 0,000 0,44597144 0,45198284 ! muscle cell differentiation GO:0042692 159 80 0,000 0,45010295 0,45597798 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,45010295 0,45578607 ! inorganic anion transport GO:0015698 138 80 0,000 0,45010295 0,45559432 ! digestion GO:0007586 112 81 0,000 0,45420379 0,45955186 ! cell-substrate adhesion GO:0031589 171 81 0,000 0,45420379 0,45935869 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,45420379 0,45916568 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,45420379 0,45897283 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,45827418 0,46289155 ! hemostasis GO:0007599 158 84 0,000 0,46632453 0,47082535 ! response to unfolded protein GO:0006986 131 85 0,000 0,47030493 0,47464499 ! nucleosome assembly GO:0006334 122 85 0,000 0,47030493 0,47444598 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,47425577 0,47823109 ! chromatin assembly GO:0031497 124 86 0,000 0,47425577 0,47803074 ! mitochondrion organization GO:0007005 148 86 0,000 0,47425577 0,47783056 ! amine transport GO:0015837 155 86 0,000 0,47425577 0,47763055 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,48206966 0,4852969 ! cellular defense response GO:0006968 114 89 0,000 0,48593314 0,48898165 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,48976792 0,49263446 ! sterol metabolic process GO:0016125 152 91 0,000 0,49357423 0,49625558 ! response to protein stimulus GO:0051789 149 91 0,000 0,49357423 0,49604829 ! regulation of defense response GO:0031347 149 92 0,000 0,49735227 0,49963656 ! nucleosome organization GO:0034728 138 92 0,000 0,49735227 0,49942803 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,49735227 0,49921968 ! vitamin metabolic process GO:0006766 139 92 0,000 0,49735227 0,49901149 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,50110225 0,50256441 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,51218589 0,51346635 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! detection of stimulus GO:0051606 151 96 0,000 0,51218589 0,5132525 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,51582569 0,51668468 ! hormone metabolic process GO:0042445 157 97 0,000 0,51582569 0,51646966 ! response to virus GO:0009615 160 98 0,000 0,51943845 0,51987059 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,51943845 0,51965443 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,52302437 0,52302437