pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6658-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! inner ear receptor cell differentiation GO:0060113 42 22 6,000 1,154E-10 2,818E-07 ! mechanoreceptor differentiation GO:0042490 48 24 6,000 2,313E-10 2,826E-07 ! lung development GO:0030324 165 69 8,000 1,334E-09 1,086E-06 ! respiratory tube development GO:0030323 171 72 8,000 1,967E-09 1,202E-06 ! respiratory system development GO:0060541 175 74 8,000 2,524E-09 1,233E-06 ! regulation of epithelial cell proliferation GO:0050678 122 45 6,000 2,677E-08 1,09E-05 ! cell growth GO:0016049 90 46 6,000 3,139E-08 1,096E-05 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 5,000 4,51E-08 1,377E-05 ! inner ear development GO:0048839 89 53 6,000 8,673E-08 2,354E-05 ! auditory receptor cell differentiation GO:0042491 36 17 4,000 9,177E-08 2,242E-05 ! positive regulation of protein complex assembly GO:0031334 34 18 4,000 1,264E-07 2,806E-05 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 4,000 1,705E-07 3,471E-05 ! regulation of protein complex assembly GO:0043254 132 63 6,000 2,934E-07 5,513E-05 ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 4,000 3,796E-07 6,624E-05 ! ear development GO:0043583 114 66 6,000 4,057E-07 6,607E-05 ! protein sumoylation GO:0016925 17 10 3,000 4,7E-07 7,177E-05 ! myeloid leukocyte differentiation GO:0002573 46 25 4,000 7,528E-07 1,082E-04 ! regulation of gene-specific transcription GO:0032583 102 46 5,000 8,052E-07 1,093E-04 ! positive regulation of cell cycle GO:0045787 96 48 5,000 1,043E-06 1,341E-04 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 5,000 2,926E-06 3,574E-04 ! positive regulation of gene-specific transcription GO:0043193 70 33 4,000 3,213E-06 3,738E-04 ! smooth muscle tissue development GO:0048745 32 5 2,000 3,321E-06 3,688E-04 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 2,000 3,321E-06 3,528E-04 ! regulation of protein localization GO:0032880 188 97 6,000 5,57E-06 5,67E-04 ! leukocyte differentiation GO:0002521 232 98 6,000 5,963E-06 5,827E-04 ! nuclear migration GO:0007097 13 6 2,000 6,608E-06 6,209E-04 ! positive regulation of pseudopodium assembly GO:0031274 15 6 2,000 6,608E-06 5,979E-04 GO:0031272|regulation of pseudopodium assembly, ! myeloid cell differentiation GO:0030099 126 67 5,000 7,592E-06 6,624E-04 ! establishment or maintenance of cell polarity GO:0007163 96 41 4,000 9,694E-06 8,167E-04 ! positive regulation of protein ubiquitination GO:0031398 14 7 2,000 1,151E-05 9,369E-04 ! regulation of protein export from nucleus GO:0046825 10 7 2,000 1,151E-05 9,067E-04 ! centrosome duplication GO:0051298 14 7 2,000 1,151E-05 8,783E-04 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 4,000 1,724E-05 1,276E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 2,000 1,831E-05 1,316E-03 ! male meiosis GO:0007140 9 8 2,000 1,831E-05 1,278E-03 ! regulation of lipid kinase activity GO:0043550 17 8 2,000 1,831E-05 1,243E-03 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 2,000 1,831E-05 1,209E-03 ! establishment of nucleus localization GO:0040023 18 8 2,000 1,831E-05 1,177E-03 ! activation of protein kinase activity GO:0032147 170 80 5,000 2,12E-05 1,328E-03 ! response to hypoxia GO:0001666 178 81 5,000 2,276E-05 1,39E-03 ! positive regulation of phosphorylation GO:0042327 149 81 5,000 2,276E-05 1,356E-03 ! liver development GO:0001889 55 25 3,000 2,607E-05 1,517E-03 ! response to oxygen levels GO:0070482 183 83 5,000 2,616E-05 1,486E-03 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 5,000 2,616E-05 1,453E-03 GO:0045937|positive regulation of phosphate metabolic process, ! artery development GO:0060840 25 9 2,000 2,733E-05 1,484E-03 GO:0048844|artery morphogenesis, ! macrophage differentiation GO:0030225 15 9 2,000 2,733E-05 1,451E-03 ! induction of an organ GO:0001759 17 10 2,000 3,884E-05 2,019E-03 ! synaptic vesicle endocytosis GO:0048488 23 10 2,000 3,884E-05 1,977E-03 ! gland development GO:0048732 220 91 5,000 4,411E-05 2,199E-03 ! nucleus localization GO:0051647 22 11 2,000 5,313E-05 2,596E-03 ! negative regulation of transcription regulator activity GO:0090048 57 30 3,000 5,496E-05 2,633E-03 GO:0043433|negative regulation of transcription factor activity, ! regulation of cell projection assembly GO:0060491 33 12 2,000 7,047E-05 3,311E-03 ! developmental induction GO:0031128 22 12 2,000 7,047E-05 3,248E-03 GO:0045168|cell-cell signaling involved in cell fate specification, ! peripheral nervous system development GO:0007422 68 32 3,000 7,133E-05 3,227E-03 ! double-strand break repair via homologous recombination GO:0000724 19 13 2,000 9,114E-05 4,048E-03 GO:0000725|recombinational repair, ! positive regulation of cell growth GO:0030307 24 13 2,000 9,114E-05 3,976E-03 ! regulation of epidermis development GO:0045682 19 13 2,000 9,114E-05 3,906E-03 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 2,000 9,114E-05 3,839E-03 ! negative regulation of DNA binding GO:0043392 67 36 3,000 1,143E-04 4,734E-03 ! cell projection assembly GO:0030031 138 68 4,000 1,157E-04 4,711E-03 ! negative regulation of protein kinase activity GO:0006469 144 69 4,000 1,24E-04 4,967E-03 ! homeostasis of number of cells GO:0048872 131 69 4,000 1,24E-04 4,887E-03 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 4,000 1,24E-04 4,81E-03 ! negative regulation of kinase activity GO:0033673 145 70 4,000 1,328E-04 5,07E-03 ! dopamine metabolic process GO:0042417 35 15 2,000 1,435E-04 5,394E-03 ! negative regulation of binding GO:0051100 71 39 3,000 1,57E-04 5,812E-03 ! erythrocyte homeostasis GO:0034101 75 39 3,000 1,57E-04 5,726E-03 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 4,000 1,728E-04 6,209E-03 ! negative regulation of transferase activity GO:0051348 155 74 4,000 1,728E-04 6,119E-03 ! regulation of protein ubiquitination GO:0031396 28 16 2,000 1,757E-04 6,132E-03 ! positive regulation of cell size GO:0045793 29 16 2,000 1,757E-04 6,046E-03 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 2,000 1,757E-04 5,962E-03 ! positive regulation of neuron apoptosis GO:0043525 32 16 2,000 1,757E-04 5,88E-03 ! regulation of transcription factor activity GO:0051090 137 75 4,000 1,841E-04 6,079E-03 GO:0090046|regulation of transcription regulator activity, ! regulation of intracellular protein transport GO:0033157 86 42 3,000 2,102E-04 6,847E-03 ! T cell differentiation GO:0030217 93 42 3,000 2,102E-04 6,757E-03 ! negative regulation of cell cycle process GO:0010948 35 17 2,000 2,123E-04 6,735E-03 ! filopodium assembly GO:0046847 42 17 2,000 2,123E-04 6,648E-03 ! patterning of blood vessels GO:0001569 43 18 2,000 2,534E-04 7,836E-03 ! centrosome cycle GO:0007098 26 18 2,000 2,534E-04 7,738E-03 ! microspike assembly GO:0030035 46 18 2,000 2,534E-04 7,643E-03 ! meiosis GO:0007126 143 81 4,000 2,642E-04 7,872E-03 GO:0051327|M phase of meiotic cell cycle, ! meiotic cell cycle GO:0051321 144 82 4,000 2,798E-04 8,235E-03 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 3,000 2,999E-04 8,721E-03 ! T cell activation GO:0042110 189 84 4,000 3,13E-04 8,996E-03 ! estrogen receptor signaling pathway GO:0030520 45 20 2,000 3,504E-04 9,954E-03 ! collagen fibril organization GO:0030199 62 21 2,000 4,067E-04 0,01142008 ! negative regulation of intracellular transport GO:0032387 44 21 2,000 4,067E-04 0,0112903 ! camera-type eye morphogenesis GO:0048593 47 21 2,000 4,067E-04 0,01116345 ! regulation of DNA binding GO:0051101 167 89 4,000 4,091E-04 0,01110556 ! positive regulation of protein modification process GO:0031401 156 90 4,000 4,308E-04 0,01156417 ! ossification GO:0001503 205 91 4,000 4,532E-04 0,01203541 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 2,000 4,685E-04 0,01230656 ! bone development GO:0060348 206 92 4,000 4,766E-04 0,01238624 ! hemoglobin biosynthetic process GO:0042541 8 5 1,000 4,782E-04 0,01229719 ! cell adhesion mediated by integrin GO:0033627 10 5 1,000 4,782E-04 0,01216909 ! embryonic camera-type eye development GO:0031076 12 5 1,000 4,782E-04 0,01204364 GO:0048596|embryonic camera-type eye morphogenesis, ! endochondral ossification GO:0001958 17 5 1,000 4,782E-04 0,01192074 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of viral genome replication GO:0045070 9 5 1,000 4,782E-04 0,01180033 ! neutrophil mediated immunity GO:0002446 7 5 1,000 4,782E-04 0,01168233 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 1,000 4,782E-04 0,01156666 ! microvillus organization GO:0032528 8 5 1,000 4,782E-04 0,01145326 GO:0030033|microvillus assembly, ! regulation of phospholipase A2 activity GO:0032429 15 5 1,000 4,782E-04 0,01134206 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 1,000 4,782E-04 0,01123301 ! meiotic chromosome segregation GO:0045132 10 5 1,000 4,782E-04 0,01112603 ! forebrain morphogenesis GO:0048853 13 5 1,000 4,782E-04 0,01102106 ! mitotic recombination GO:0006312 9 5 1,000 4,782E-04 0,01091806 ! positive regulation of chemokine production GO:0032722 8 5 1,000 4,782E-04 0,01081697 ! muscle cell proliferation GO:0033002 12 5 1,000 4,782E-04 0,01071773 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 1,000 4,782E-04 0,0106203 ! regulation of hair follicle development GO:0051797 10 5 1,000 4,782E-04 0,01052462 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 1,000 4,782E-04 0,01043065 ! glial cell migration GO:0008347 10 5 1,000 4,782E-04 0,01033834 ! inner cell mass cell proliferation GO:0001833 5 5 1,000 4,782E-04 0,01024765 ! regulation of sensory perception GO:0051931 8 5 1,000 4,782E-04 0,01015854 GO:0051930|regulation of sensory perception of pain, ! protein insertion into membrane GO:0051205 17 5 1,000 4,782E-04 0,01007097 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 1,000 4,782E-04 9,985E-03 GO:0022011|myelination in the peripheral nervous system, ! stem cell division GO:0017145 11 5 1,000 4,782E-04 9,9E-03 GO:0048103|somatic stem cell division, ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 3,000 5,179E-04 0,01063252 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 2,000 5,36E-04 0,01091187 ! response to UV GO:0009411 120 55 3,000 5,967E-04 0,01204706 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 2,000 6,094E-04 0,01220327 ! negative regulation of phosphorylation GO:0042326 52 24 2,000 6,094E-04 0,01210405 ! synaptic vesicle transport GO:0048489 52 24 2,000 6,094E-04 0,01200644 ! interphase of mitotic cell cycle GO:0051329 224 98 4,000 6,363E-04 0,01243491 ! forebrain development GO:0030900 210 98 4,000 6,363E-04 0,01233622 ! regulation of intracellular transport GO:0032386 108 57 3,000 6,836E-04 0,01314969 ! vasculogenesis GO:0001570 49 25 2,000 6,89E-04 0,01314945 ! regulation of smooth muscle cell differentiation GO:0051150 12 6 1,000 7,14E-04 0,01352153 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 1,000 7,14E-04 0,01341751 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! regulation of retroviral genome replication GO:0045091 8 6 1,000 7,14E-04 0,01331509 ! early endosome to late endosome transport GO:0045022 16 6 1,000 7,14E-04 0,01321422 ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 1,000 7,14E-04 0,01311486 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! establishment of spindle localization GO:0051293 16 6 1,000 7,14E-04 0,01301699 GO:0051653|spindle localization, ! negative regulation of gliogenesis GO:0014014 18 6 1,000 7,14E-04 0,01292057 GO:0045686|negative regulation of glial cell differentiation, ! astrocyte development GO:0014002 16 6 1,000 7,14E-04 0,01282556 ! enucleate erythrocyte differentiation GO:0043353 14 6 1,000 7,14E-04 0,01273195 ! positive regulation of actin filament polymerization GO:0030838 11 6 1,000 7,14E-04 0,01263969 ! erythrocyte maturation GO:0043249 8 6 1,000 7,14E-04 0,01254875 ! embryonic hemopoiesis GO:0035162 16 6 1,000 7,14E-04 0,01245912 ! activation of MAPKKK activity GO:0000185 12 6 1,000 7,14E-04 0,01237076 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 1,000 7,14E-04 0,01228364 ! response to UV-C GO:0010225 14 6 1,000 7,14E-04 0,01219774 ! Schwann cell development GO:0014044 15 6 1,000 7,14E-04 0,01211303 ! regulation of myeloid cell apoptosis GO:0033032 14 6 1,000 7,14E-04 0,01202949 ! myeloid dendritic cell activation GO:0001773 10 6 1,000 7,14E-04 0,0119471 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 1,000 7,14E-04 0,01186583 ! negative regulation of neuroblast proliferation GO:0007406 25 6 1,000 7,14E-04 0,01178565 ! positive regulation of cell migration GO:0030335 137 58 3,000 7,302E-04 0,01197299 ! microtubule organizing center organization GO:0031023 42 26 2,000 7,748E-04 0,01261935 GO:0051297|centrosome organization, ! negative regulation of phosphorus metabolic process GO:0010563 56 26 2,000 7,748E-04 0,01253578 GO:0045936|negative regulation of phosphate metabolic process, ! osteoblast differentiation GO:0001649 63 26 2,000 7,748E-04 0,01245331 ! blastocyst development GO:0001824 50 26 2,000 7,748E-04 0,01237191 ! establishment of organelle localization GO:0051656 122 59 3,000 7,791E-04 0,01235928 ! positive regulation of cell projection organization GO:0031346 66 27 2,000 8,672E-04 0,01366832 ! regulation of homeostatic process GO:0032844 148 62 3,000 9,395E-04 0,01471236 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 2,000 9,663E-04 0,01503598 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 1,000 9,95E-04 0,01538446 GO:0045346|regulation of MHC class II biosynthetic process, ! cytokinesis during cell cycle GO:0033205 14 7 1,000 9,95E-04 0,0152877 ! prostate gland development GO:0030850 14 7 1,000 9,95E-04 0,01519215 ! N-terminal protein amino acid acetylation GO:0006474 14 7 1,000 9,95E-04 0,01509779 ! adrenal gland development GO:0030325 17 7 1,000 9,95E-04 0,0150046 ! vesicle fusion GO:0006906 20 7 1,000 9,95E-04 0,01491254 ! positive regulation of mitotic cell cycle GO:0045931 14 7 1,000 9,95E-04 0,01482161 ! spindle checkpoint GO:0031577 16 7 1,000 9,95E-04 0,01473179 ! wound healing, spreading of epidermal cells GO:0035313 16 7 1,000 9,95E-04 0,01464304 ! monocyte differentiation GO:0030224 16 7 1,000 9,95E-04 0,01455536 ! negative regulation of nuclear division GO:0051784 15 7 1,000 9,95E-04 0,01446872 GO:0045839|negative regulation of mitosis, ! regulation of epidermal cell differentiation GO:0045604 8 7 1,000 9,95E-04 0,0143831 ! dopamine biosynthetic process GO:0042416 18 7 1,000 9,95E-04 0,0142985 ! embryonic heart tube development GO:0035050 14 7 1,000 9,95E-04 0,01421488 ! catechol metabolic process GO:0009712 55 29 2,000 1,072E-03 0,01522983 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! positive regulation of cell motion GO:0051272 157 65 3,000 1,122E-03 0,01584081 ! phenol metabolic process GO:0018958 56 30 2,000 1,185E-03 0,01664178 ! negative regulation of protein complex assembly GO:0031333 68 30 2,000 1,185E-03 0,01654669 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 2,000 1,185E-03 0,01645267 ! steroid hormone receptor signaling pathway GO:0030518 146 66 3,000 1,188E-03 0,01639238 ! chromosome segregation GO:0007059 127 67 3,000 1,256E-03 0,01724129 ! erythrocyte differentiation GO:0030218 62 31 2,000 1,306E-03 0,0178184 ! eye morphogenesis GO:0048592 65 31 2,000 1,306E-03 0,01771941 ! negative regulation of muscle cell differentiation GO:0051148 17 8 1,000 1,321E-03 0,01782365 ! endothelial cell differentiation GO:0045446 17 8 1,000 1,321E-03 0,01772571 ! hemoglobin metabolic process GO:0020027 14 8 1,000 1,321E-03 0,01762885 ! astrocyte differentiation GO:0048708 19 8 1,000 1,321E-03 0,01753304 ! histidine catabolic process GO:0006548 10 8 1,000 1,321E-03 0,01743827 GO:0009077|histidine family amino acid catabolic process, ! ER overload response GO:0006983 13 8 1,000 1,321E-03 0,01734452 ! embryonic eye morphogenesis GO:0048048 16 8 1,000 1,321E-03 0,01725176 ! Schwann cell differentiation GO:0014037 21 8 1,000 1,321E-03 0,01716 ! DNA topological change GO:0006265 12 8 1,000 1,321E-03 0,01706921 ! positive regulation of epidermis development GO:0045684 13 8 1,000 1,321E-03 0,01697937 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 1,000 1,321E-03 0,01689047 GO:0002688|regulation of leukocyte chemotaxis, ! blastocyst growth GO:0001832 19 8 1,000 1,321E-03 0,0168025 ! trophectodermal cell differentiation GO:0001829 13 8 1,000 1,321E-03 0,01671544 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 3,000 1,558E-03 0,01962261 ! negative regulation of protein transport GO:0051224 74 33 2,000 1,568E-03 0,01965042 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 1,000 1,69E-03 0,02106501 GO:0010469|regulation of receptor activity, ! equilibrioception GO:0050957 20 9 1,000 1,69E-03 0,02095808 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 1,000 1,69E-03 0,02085223 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 1,000 1,69E-03 0,02074745 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 1,000 1,69E-03 0,02064371 ! erythrocyte development GO:0048821 17 9 1,000 1,69E-03 0,02054101 ! neuromuscular process controlling posture GO:0050884 15 9 1,000 1,69E-03 0,02043932 ! cell fate specification GO:0001708 56 34 2,000 1,711E-03 0,02059676 ! organelle localization GO:0051640 155 74 3,000 1,816E-03 0,02174151 ! calcium-mediated signaling GO:0019722 67 35 2,000 1,862E-03 0,02219377 ! eye development GO:0001654 155 75 3,000 1,907E-03 0,02262039 ! lymphocyte differentiation GO:0030098 193 76 3,000 2,002E-03 0,02363324 ! mitotic sister chromatid segregation GO:0000070 63 36 2,000 2,021E-03 0,02374012 ! embryonic organ development GO:0048568 67 36 2,000 2,021E-03 0,02362653 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 1,000 2,103E-03 0,02446289 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 1,000 2,103E-03 0,02434695 ! positive regulation of B cell proliferation GO:0030890 18 10 1,000 2,103E-03 0,02423211 ! regulation of phosphatase activity GO:0010921 28 10 1,000 2,103E-03 0,02411834 ! SMAD protein nuclear translocation GO:0007184 21 10 1,000 2,103E-03 0,02400564 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 1,000 2,103E-03 0,02389399 ! positive regulation of heart contraction GO:0045823 17 10 1,000 2,103E-03 0,02378337 ! negative regulation of striated muscle development GO:0045843 26 10 1,000 2,103E-03 0,02367377 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 1,000 2,103E-03 0,02356517 ! positive regulation of survival gene product expression GO:0045885 26 10 1,000 2,103E-03 0,02345757 ! myeloid leukocyte mediated immunity GO:0002444 14 10 1,000 2,103E-03 0,02335094 ! multicellular organism growth GO:0035264 19 10 1,000 2,103E-03 0,02324528 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 1,000 2,103E-03 0,02314057 ! regulation of bone resorption GO:0045124 25 10 1,000 2,103E-03 0,0230368 ! regulation of gliogenesis GO:0014013 23 10 1,000 2,103E-03 0,02293396 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 1,000 2,103E-03 0,02283203 ! DNA ligation GO:0006266 18 10 1,000 2,103E-03 0,02273101 ! negative regulation of MAPKKK cascade GO:0043409 20 10 1,000 2,103E-03 0,02263087 ! salivary gland development GO:0007431 28 10 1,000 2,103E-03 0,02253161 ! methionine biosynthetic process GO:0009086 21 10 1,000 2,103E-03 0,02243322 ! positive regulation of viral reproduction GO:0048524 19 10 1,000 2,103E-03 0,02233568 ! blastocyst formation GO:0001825 18 10 1,000 2,103E-03 0,02223899 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 1,000 2,103E-03 0,02214314 ! sister chromatid segregation GO:0000819 65 37 2,000 2,188E-03 0,02294492 ! positive regulation of lymphocyte activation GO:0051251 142 78 3,000 2,202E-03 0,02299325 ! positive regulation of DNA metabolic process GO:0051054 77 38 2,000 2,364E-03 0,02457336 ! meiosis I GO:0007127 74 38 2,000 2,364E-03 0,02446923 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 3,000 2,416E-03 0,02490028 ! positive regulation of leukocyte proliferation GO:0070665 70 39 2,000 2,548E-03 0,02615125 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! negative regulation of muscle development GO:0048635 27 11 1,000 2,558E-03 0,02615049 ! thyroid gland development GO:0030878 26 11 1,000 2,558E-03 0,02604153 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 1,000 2,558E-03 0,02593347 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 1,000 2,558E-03 0,02582631 ! blood vessel remodeling GO:0001974 30 11 1,000 2,558E-03 0,02572003 ! peptide or protein amino-terminal blocking GO:0018409 22 11 1,000 2,558E-03 0,02561462 ! histidine metabolic process GO:0006547 22 11 1,000 2,558E-03 0,02551007 GO:0009075|histidine family amino acid metabolic process, ! adult heart development GO:0007512 16 11 1,000 2,558E-03 0,02540637 ! chondrocyte differentiation GO:0002062 27 11 1,000 2,558E-03 0,02530351 ! positive regulation of leukocyte migration GO:0002687 28 11 1,000 2,558E-03 0,02520148 ! thymus development GO:0048538 29 11 1,000 2,558E-03 0,02510027 ! oocyte development GO:0048599 20 11 1,000 2,558E-03 0,02499987 ! gliogenesis GO:0042063 91 41 2,000 2,941E-03 0,02862903 ! regulation of B cell proliferation GO:0030888 22 12 1,000 3,056E-03 0,02962511 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 1,000 3,056E-03 0,02950802 ! entry into host cell GO:0030260 34 12 1,000 3,056E-03 0,02939184 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! regulation of interleukin-8 production GO:0032677 22 12 1,000 3,056E-03 0,02927658 ! histone acetylation GO:0016573 27 12 1,000 3,056E-03 0,02916222 ! autonomic nervous system development GO:0048483 24 12 1,000 3,056E-03 0,02904875 ! peptidyl-lysine modification GO:0018205 21 12 1,000 3,056E-03 0,02893616 ! T cell homeostasis GO:0043029 28 12 1,000 3,056E-03 0,02882443 ! regulation of leukocyte migration GO:0002685 29 12 1,000 3,056E-03 0,02871357 ! oocyte differentiation GO:0009994 21 12 1,000 3,056E-03 0,02860356 ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 1,000 3,056E-03 0,02849438 ! embryonic placenta development GO:0001892 21 12 1,000 3,056E-03 0,02838604 ! lamellipodium assembly GO:0030032 24 12 1,000 3,056E-03 0,02827852 ! localization within membrane GO:0051668 26 12 1,000 3,056E-03 0,0281718 ! positive regulation of cell activation GO:0050867 161 86 3,000 3,14E-03 0,02883625 GO:0002696|positive regulation of leukocyte activation, ! cytokinesis GO:0000910 84 42 2,000 3,152E-03 0,02883574 ! regulation of protein transport GO:0051223 165 87 3,000 3,273E-03 0,02983856 GO:0070201|regulation of establishment of protein localization, ! tube morphogenesis GO:0035239 194 89 3,000 3,552E-03 0,03225811 ! regulation of chemokine production GO:0032642 18 13 1,000 3,595E-03 0,03252746 ! folic acid and derivative biosynthetic process GO:0009396 25 13 1,000 3,595E-03 0,03240743 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 1,000 3,595E-03 0,03228829 ! organelle fusion GO:0048284 36 13 1,000 3,595E-03 0,03217002 ! methionine metabolic process GO:0006555 31 13 1,000 3,595E-03 0,03205261 ! response to X-ray GO:0010165 28 13 1,000 3,595E-03 0,03193605 ! cellular carbohydrate catabolic process GO:0044275 17 13 1,000 3,595E-03 0,03182034 ! exocrine system development GO:0035272 34 13 1,000 3,595E-03 0,03170547 ! membrane protein proteolysis GO:0033619 33 13 1,000 3,595E-03 0,03159142 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of monooxygenase activity GO:0032768 35 13 1,000 3,595E-03 0,03147819 ! gland morphogenesis GO:0022612 31 13 1,000 3,595E-03 0,03136576 ! regulation of erythrocyte differentiation GO:0045646 47 13 1,000 3,595E-03 0,03125414 ! spleen development GO:0048536 24 13 1,000 3,595E-03 0,03114331 ! acrosome reaction GO:0007340 19 13 1,000 3,595E-03 0,03103327 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 2,000 3,599E-03 0,03095695 ! double-strand break repair GO:0006302 85 44 2,000 3,599E-03 0,03084833 ! regulation of cell cycle process GO:0010564 161 90 3,000 3,697E-03 0,03158072 ! branching morphogenesis of a tube GO:0048754 102 45 2,000 3,836E-03 0,03265409 ! induction of apoptosis by intracellular signals GO:0008629 95 45 2,000 3,836E-03 0,0325407 ! B cell differentiation GO:0030183 124 45 2,000 3,836E-03 0,03242811 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 1,000 4,175E-03 0,03516953 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 1,000 4,175E-03 0,03504867 ! hair follicle morphogenesis GO:0031069 27 14 1,000 4,175E-03 0,03492864 ! palate development GO:0060021 32 14 1,000 4,175E-03 0,03480943 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 1,000 4,175E-03 0,03469103 ! embryo implantation GO:0007566 30 14 1,000 4,175E-03 0,03457344 ! negative regulation of protein import into nucleus GO:0042308 33 14 1,000 4,175E-03 0,03445663 ! T cell differentiation in the thymus GO:0033077 37 14 1,000 4,175E-03 0,03434062 ! positive regulation of Ras GTPase activity GO:0032320 42 14 1,000 4,175E-03 0,03422538 ! response to gamma radiation GO:0010332 30 14 1,000 4,175E-03 0,03411091 ! catecholamine biosynthetic process GO:0042423 30 14 1,000 4,175E-03 0,03399721 ! positive regulation of protein polymerization GO:0032273 27 14 1,000 4,175E-03 0,03388426 ! JAK-STAT cascade GO:0007259 82 48 2,000 4,605E-03 0,0372494 ! N-terminal protein amino acid modification GO:0031365 30 15 1,000 4,795E-03 0,03866115 ! reproductive cellular process GO:0048610 22 15 1,000 4,795E-03 0,03853398 ! positive regulation of GTPase activity GO:0043547 43 15 1,000 4,795E-03 0,03840764 ! regulation of mRNA processing GO:0050684 26 15 1,000 4,795E-03 0,03828212 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 1,000 4,795E-03 0,03815743 ! lymphocyte homeostasis GO:0002260 33 15 1,000 4,795E-03 0,03803354 ! epithelial to mesenchymal transition GO:0001837 30 15 1,000 4,795E-03 0,03791045 ! regulation of DNA metabolic process GO:0051052 188 97 3,000 4,827E-03 0,03804277 ! regulation of mast cell proliferation GO:0070666 89 49 2,000 4,88E-03 0,03833423 ! endocrine system development GO:0035270 109 50 2,000 5,165E-03 0,04044345 ! sulfur amino acid biosynthetic process GO:0000097 31 16 1,000 5,455E-03 0,04257662 ! regulation of neurotransmitter secretion GO:0046928 35 16 1,000 5,455E-03 0,04244102 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 1,000 5,455E-03 0,04230629 ! startle response GO:0001964 28 16 1,000 5,455E-03 0,04217241 ! regulation of dephosphorylation GO:0035303 43 16 1,000 5,455E-03 0,04203937 ! negative regulation of immune response GO:0050777 38 16 1,000 5,455E-03 0,04190718 ! neuromuscular synaptic transmission GO:0007274 34 16 1,000 5,455E-03 0,0417758 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 1,000 5,455E-03 0,04164526 ! regulation of cell projection organization GO:0031344 135 51 2,000 5,46E-03 0,04155383 ! response to estrogen stimulus GO:0043627 98 52 2,000 5,765E-03 0,04373735 ! DNA-dependent DNA replication GO:0006261 82 52 2,000 5,765E-03 0,04360194 ! morphogenesis of a branching structure GO:0001763 116 52 2,000 5,765E-03 0,04346737 ! positive regulation of growth GO:0045927 96 53 2,000 6,08E-03 0,04570005 ! chromatin remodeling GO:0006338 122 53 2,000 6,08E-03 0,04555987 ! regulation of leukocyte proliferation GO:0070663 97 53 2,000 6,08E-03 0,04542054 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of neuron apoptosis GO:0043523 117 53 2,000 6,08E-03 0,04528206 ! embryonic forelimb morphogenesis GO:0035115 31 17 1,000 6,154E-03 0,04569667 ! signal complex assembly GO:0007172 47 17 1,000 6,154E-03 0,04555819 ! glial cell development GO:0021782 28 17 1,000 6,154E-03 0,04542056 ! regulation of muscle cell differentiation GO:0051147 36 17 1,000 6,154E-03 0,04528375 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 1,000 6,154E-03 0,04514776 ! activation of MAPKK activity GO:0000186 43 17 1,000 6,154E-03 0,04501259 ! regulation of survival gene product expression GO:0045884 38 17 1,000 6,154E-03 0,04487822 ! DNA unwinding during replication GO:0006268 26 17 1,000 6,154E-03 0,04474465 ! neutrophil chemotaxis GO:0030593 29 17 1,000 6,154E-03 0,04461188 ! regulation of angiogenesis GO:0045765 125 54 2,000 6,405E-03 0,04629068 ! neuromuscular process GO:0050905 107 54 2,000 6,405E-03 0,04615413 ! embryonic skeletal system development GO:0048706 101 54 2,000 6,405E-03 0,04601838 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 2,000 6,74E-03 0,04828393 ! cell maturation GO:0048469 107 55 2,000 6,74E-03 0,04814275 ! heart looping GO:0001947 34 18 1,000 6,892E-03 0,04908482 ! regulation of viral genome replication GO:0045069 30 18 1,000 6,892E-03 0,04894214 ! epidermis morphogenesis GO:0048730 43 18 1,000 6,892E-03 0,04880027 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 1,000 6,892E-03 0,04865923 ! negative regulation of protein catabolic process GO:0042177 42 18 1,000 6,892E-03 0,048519 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 1,000 6,892E-03 0,04837958 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 1,000 6,892E-03 0,04824096 ! regulation of BMP signaling pathway GO:0030510 33 18 1,000 6,892E-03 0,04810313 ! regulation of protein catabolic process GO:0042176 126 56 2,000 7,085E-03 0,04931173 ! regulation of DNA replication GO:0006275 105 56 2,000 7,085E-03 0,04917163 ! regulation of bone remodeling GO:0046850 143 57 2,000 7,441E-03 0,05149353 ! heart morphogenesis GO:0003007 105 57 2,000 7,441E-03 0,05134807 ! nucleotide-excision repair GO:0006289 91 57 2,000 7,441E-03 0,05120342 ! cellular response to hydrogen peroxide GO:0070301 25 19 1,000 7,667E-03 0,05261452 GO:0042744|hydrogen peroxide catabolic process, ! cerebral cortex development GO:0021987 40 19 1,000 7,667E-03 0,05246714 ! response to lipopolysaccharide GO:0032496 34 19 1,000 7,667E-03 0,05232058 ! regulation of endothelial cell migration GO:0010594 45 19 1,000 7,667E-03 0,05217484 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 1,000 7,667E-03 0,05202991 ! visual learning GO:0008542 38 19 1,000 7,667E-03 0,05188578 ! folic acid and derivative metabolic process GO:0006760 39 19 1,000 7,667E-03 0,05174245 ! embryonic organ morphogenesis GO:0048562 34 19 1,000 7,667E-03 0,05159991 ! regulation of actin filament length GO:0030832 118 58 2,000 7,807E-03 0,05239394 ! regulation of tissue remodeling GO:0034103 146 58 2,000 7,807E-03 0,05225039 ! positive regulation of organelle organization GO:0010638 108 58 2,000 7,807E-03 0,05210763 ! positive regulation of ossification GO:0045778 50 20 1,000 8,48E-03 0,05644919 ! phosphoinositide phosphorylation GO:0046854 40 20 1,000 8,48E-03 0,05629579 ! protein amino acid acetylation GO:0006473 41 20 1,000 8,48E-03 0,05614323 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 1,000 8,48E-03 0,05599149 ! forelimb morphogenesis GO:0035136 35 20 1,000 8,48E-03 0,05584057 ! DNA duplex unwinding GO:0032508 30 20 1,000 8,48E-03 0,05569046 GO:0032392|DNA geometric change, ! peptidyl-serine phosphorylation GO:0018105 44 20 1,000 8,48E-03 0,05554116 ! behavioral interaction between organisms GO:0051705 47 20 1,000 8,48E-03 0,05539265 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 1,000 8,48E-03 0,05524494 ! regulation of cellular component size GO:0032535 125 61 2,000 8,968E-03 0,0582654 ! camera-type eye development GO:0043010 126 61 2,000 8,968E-03 0,05811085 ! lipid phosphorylation GO:0046834 43 21 1,000 9,33E-03 0,06029891 ! regulation of neurotransmitter transport GO:0051588 44 21 1,000 9,33E-03 0,06013981 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 1,000 9,33E-03 0,05998155 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 1,000 9,33E-03 0,05982412 ! ribosomal small subunit biogenesis GO:0042274 25 21 1,000 9,33E-03 0,05966751 ! negative regulation of angiogenesis GO:0016525 49 21 1,000 9,33E-03 0,05951172 ! regulation of mitosis GO:0007088 112 63 2,000 9,795E-03 0,0623136 GO:0051783|regulation of nuclear division, ! skeletal system morphogenesis GO:0048705 118 63 2,000 9,795E-03 0,06215175 ! positive regulation of protein catabolic process GO:0045732 44 22 1,000 0,01021606 0,06465761 ! reciprocal meiotic recombination GO:0007131 44 22 1,000 0,01021606 0,06449053 ! positive regulation of bone remodeling GO:0046852 54 22 1,000 0,01021606 0,06432432 GO:0034105|positive regulation of tissue remodeling, ! hindlimb morphogenesis GO:0035137 47 22 1,000 0,01021606 0,06415896 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 1,000 0,01021606 0,06399445 ! apoptotic nuclear changes GO:0030262 34 22 1,000 0,01021606 0,06383079 ! cell aging GO:0007569 48 22 1,000 0,01021606 0,06366795 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 1,000 0,01021606 0,06350595 ! positive regulation of locomotion GO:0040017 44 22 1,000 0,01021606 0,06334476 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! positive regulation of intracellular transport GO:0032388 42 22 1,000 0,01021606 0,0631844 ! peptidyl-serine modification GO:0018209 50 22 1,000 0,01021606 0,06302484 ! positive regulation of B cell activation GO:0050871 42 22 1,000 0,01021606 0,06286609 ! protein stabilization GO:0050821 41 22 1,000 0,01021606 0,06270813 ! protein amino acid autophosphorylation GO:0046777 157 64 2,000 0,01022434 0,06260165 ! regulation of lipid metabolic process GO:0019216 132 66 2,000 0,01111608 0,06789144 ! sulfur amino acid metabolic process GO:0000096 48 23 1,000 0,01113797 0,06785553 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 1,000 0,01113797 0,06768673 ! regulation of chemotaxis GO:0050920 45 23 1,000 0,01113797 0,06751878 ! visual behavior GO:0007632 46 23 1,000 0,01113797 0,06735165 ! regulation of cell-matrix adhesion GO:0001952 81 23 1,000 0,01113797 0,06718535 GO:0010810|regulation of cell-substrate adhesion, ! negative regulation of cytokine production GO:0001818 41 23 1,000 0,01113797 0,06701987 ! acetyl-CoA catabolic process GO:0046356 37 23 1,000 0,01113797 0,0668552 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 1,000 0,01113797 0,06669134 ! positive regulation of DNA replication GO:0045740 44 23 1,000 0,01113797 0,06652828 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 1,000 0,01113797 0,06636602 ! cellular response to reactive oxygen species GO:0034614 35 23 1,000 0,01113797 0,06620454 ! negative regulation of cell growth GO:0030308 142 67 2,000 0,01157826 0,06865458 ! extracellular matrix organization GO:0030198 146 68 2,000 0,01205137 0,07128692 ! positive regulation of T cell activation GO:0050870 124 68 2,000 0,01205137 0,07111473 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 2,000 0,01205137 0,07094337 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 1,000 0,01209511 0,07102972 ! positive regulation of cell adhesion GO:0045785 61 24 1,000 0,01209511 0,07085939 ! calcium-independent cell-cell adhesion GO:0016338 36 24 1,000 0,01209511 0,07068987 ! central nervous system neuron differentiation GO:0021953 51 24 1,000 0,01209511 0,07052115 ! positive regulation of cytoskeleton organization GO:0051495 52 24 1,000 0,01209511 0,07035325 ! regulation of viral reproduction GO:0050792 41 24 1,000 0,01209511 0,07018614 ! pallium development GO:0021543 56 24 1,000 0,01209511 0,07001982 ! oogenesis GO:0048477 44 24 1,000 0,01209511 0,06985429 ! regulation of oxidoreductase activity GO:0051341 48 24 1,000 0,01209511 0,06968954 ! aspartate family amino acid metabolic process GO:0009066 47 24 1,000 0,01209511 0,06952556 ! negative regulation of catabolic process GO:0009895 52 24 1,000 0,01209511 0,06936236 ! negative regulation of cell size GO:0045792 144 69 2,000 0,01253545 0,07171923 ! urogenital system development GO:0001655 149 69 2,000 0,01253545 0,07155166 ! developmental maturation GO:0021700 128 69 2,000 0,01253545 0,07138487 ! protein import into nucleus, translocation GO:0000060 51 25 1,000 0,01308695 0,07435216 ! positive regulation of fibroblast proliferation GO:0048146 48 25 1,000 0,01308695 0,07417965 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 1,000 0,01308695 0,07400793 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 1,000 0,01308695 0,07383702 ! negative regulation of DNA replication GO:0008156 45 25 1,000 0,01308695 0,07366688 ! chromosome condensation GO:0030261 48 25 1,000 0,01308695 0,07349754 ! regulation of behavior GO:0050795 48 25 1,000 0,01308695 0,07332896 ! regulation of alpha-beta T cell activation GO:0046634 48 25 1,000 0,01308695 0,07316116 ! interaction with host GO:0051701 66 25 1,000 0,01308695 0,07299413 ! leukocyte homeostasis GO:0001776 50 25 1,000 0,01308695 0,07282785 ! B cell activation GO:0042113 179 72 2,000 0,01405388 0,07803096 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 2,000 0,01405388 0,07785401 ! regulation of MAPKKK cascade GO:0043408 157 72 2,000 0,01405388 0,07767787 ! myelination GO:0042552 50 26 1,000 0,01411296 0,07782838 ! initiation of viral infection GO:0019059 60 26 1,000 0,01411296 0,07765309 ! molting cycle process GO:0022404 52 26 1,000 0,01411296 0,07747859 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! regulation of transcription factor import into nucleus GO:0042990 58 26 1,000 0,01411296 0,07730487 ! spinal cord development GO:0021510 54 26 1,000 0,01411296 0,07713193 ! response to endoplasmic reticulum stress GO:0034976 46 26 1,000 0,01411296 0,07695976 ! coenzyme catabolic process GO:0009109 42 26 1,000 0,01411296 0,07678836 ! negative regulation of cell development GO:0010721 83 26 1,000 0,01411296 0,07661771 GO:0050768|negative regulation of neurogenesis, ! hydrogen peroxide metabolic process GO:0042743 35 26 1,000 0,01411296 0,07644783 ! positive regulation of MAPKKK cascade GO:0043410 50 26 1,000 0,01411296 0,0762787 ! positive regulation of nuclear division GO:0051785 41 26 1,000 0,01411296 0,07611031 GO:0045840|positive regulation of mitosis, ! neural tube closure GO:0001843 58 26 1,000 0,01411296 0,07594267 GO:0060606|tube closure, ! acetyl-CoA metabolic process GO:0006084 41 27 1,000 0,01517262 0,08146532 ! tube lumen formation GO:0035148 59 27 1,000 0,01517262 0,08128667 ! insulin receptor signaling pathway GO:0008286 66 27 1,000 0,01517262 0,0811088 ! regulation of endothelial cell proliferation GO:0001936 60 27 1,000 0,01517262 0,08093171 ! cellular response to oxidative stress GO:0034599 43 27 1,000 0,01517262 0,08075539 ! regulation of chromosome organization GO:0033044 49 27 1,000 0,01517262 0,08057983 ! reproductive structure development GO:0048608 131 75 2,000 0,01567221 0,08305253 ! regulation of actin cytoskeleton organization GO:0032956 167 76 2,000 0,01623398 0,08584333 ! learning or memory GO:0007611 161 76 2,000 0,01623398 0,08565793 ! regulation of fibroblast proliferation GO:0048145 56 28 1,000 0,01626542 0,08563884 ! protein amino acid acylation GO:0043543 59 28 1,000 0,01626542 0,08545467 ! circadian rhythm GO:0007623 56 28 1,000 0,01626542 0,08527129 ! negative regulation of protein modification process GO:0031400 66 28 1,000 0,01626542 0,08508869 ! positive regulation of T cell differentiation GO:0045582 48 28 1,000 0,01626542 0,08490688 ! group transfer coenzyme metabolic process GO:0006752 53 28 1,000 0,01626542 0,08472584 ! regulation of catabolic process GO:0009894 173 77 2,000 0,01680695 0,08736038 ! translational initiation GO:0006413 66 29 1,000 0,01739084 0,09020344 ! cellular iron ion homeostasis GO:0006879 57 29 1,000 0,01739084 0,09001233 ! ER-nuclear signaling pathway GO:0006984 52 29 1,000 0,01739084 0,08982203 ! primary neural tube formation GO:0014020 61 29 1,000 0,01739084 0,08963253 ! response to organic cyclic substance GO:0014070 58 29 1,000 0,01739084 0,08944383 ! somitogenesis GO:0001756 52 29 1,000 0,01739084 0,08925592 ! synaptogenesis GO:0007416 46 29 1,000 0,01739084 0,0890688 ! neuromuscular process controlling balance GO:0050885 67 29 1,000 0,01739084 0,08888247 ! regulation of actin filament-based process GO:0032970 170 79 2,000 0,01798655 0,09173514 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 2,000 0,01798655 0,09154403 ! response to steroid hormone stimulus GO:0048545 147 79 2,000 0,01798655 0,09135371 ! negative regulation of protein kinase cascade GO:0010741 72 30 1,000 0,01854838 0,0940118 ! tissue homeostasis GO:0001894 50 30 1,000 0,01854838 0,09381716 GO:0048871|multicellular organismal homeostasis, ! regulation of B cell activation GO:0050864 55 30 1,000 0,01854838 0,09362332 ! negative regulation of organelle organization GO:0010639 181 80 2,000 0,01859321 0,09365609 ! iron ion homeostasis GO:0055072 60 31 1,000 0,01973754 0,09921565 ! cellular response to extracellular stimulus GO:0031668 52 31 1,000 0,01973754 0,09901192 ! natural killer cell activation GO:0030101 50 31 1,000 0,01973754 0,09880902 ! ensheathment of neurons GO:0007272 64 31 1,000 0,01973754 0,09860696 GO:0008366|axon ensheathment, ! cofactor catabolic process GO:0051187 54 31 1,000 0,01973754 0,09840572 ! response to drug GO:0042493 149 83 2,000 0,02048076 0,10190326 ! spindle organization GO:0007051 50 32 1,000 0,02095782 0,10406497 ! positive regulation of T cell proliferation GO:0042102 60 32 1,000 0,02095782 0,10385388 ! metanephros development GO:0001656 81 32 1,000 0,02095782 0,10364365 ! response to mechanical stimulus GO:0009612 60 32 1,000 0,02095782 0,10343427 ! regulation of protein import into nucleus GO:0042306 69 32 1,000 0,02095782 0,10322573 ! hindbrain development GO:0030902 65 32 1,000 0,02095782 0,10301803 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 1,000 0,02095782 0,10281117 ! myeloid leukocyte activation GO:0002274 53 32 1,000 0,02095782 0,10260514 ! positive regulation of catabolic process GO:0009896 72 32 1,000 0,02095782 0,10239993 ! regulation of ligase activity GO:0051340 147 84 2,000 0,0211325 0,10304729 ! negative regulation of transport GO:0051051 164 85 2,000 0,02179552 0,10606862 ! negative regulation of growth GO:0045926 168 85 2,000 0,02179552 0,10585775 ! response to ionizing radiation GO:0010212 74 33 1,000 0,02220875 0,10765074 ! leukocyte chemotaxis GO:0030595 55 33 1,000 0,02220875 0,10743757 GO:0060326|cell chemotaxis, ! response to hydrogen peroxide GO:0042542 56 34 1,000 0,02348983 0,11341037 ! glial cell differentiation GO:0010001 67 34 1,000 0,02348983 0,11318668 ! negative regulation of MAP kinase activity GO:0043407 78 34 1,000 0,02348983 0,11296387 ! adult locomotory behavior GO:0008344 62 34 1,000 0,02348983 0,11274194 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 1,000 0,02348983 0,11252088 ! amine biosynthetic process GO:0009309 146 88 2,000 0,02385228 0,11403352 ! regulation of neurological system process GO:0031644 175 89 2,000 0,02456043 0,11718973 ! mRNA export from nucleus GO:0006406 53 35 1,000 0,02480058 0,11810492 ! negative regulation of DNA metabolic process GO:0051053 65 35 1,000 0,02480058 0,11787515 ! regulation of striated muscle tissue development GO:0016202 81 35 1,000 0,02480058 0,11764626 ! telencephalon development GO:0021537 81 35 1,000 0,02480058 0,11741827 ! biogenic amine biosynthetic process GO:0042401 65 35 1,000 0,02480058 0,11719115 ! placenta development GO:0001890 53 35 1,000 0,02480058 0,11696491 ! regulation of muscle development GO:0048634 82 36 1,000 0,02614054 0,12304691 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 1,000 0,02614054 0,12281028 ! positive regulation of cell development GO:0010720 85 36 1,000 0,02614054 0,12257456 ! negative regulation of hydrolase activity GO:0051346 66 36 1,000 0,02614054 0,12233975 ! aerobic respiration GO:0009060 56 36 1,000 0,02614054 0,12210583 ! regulation of cell adhesion GO:0030155 241 92 2,000 0,0267525 0,12472585 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 2,000 0,02750569 0,12799314 GO:0010498|proteasomal protein catabolic process, ! tissue remodeling GO:0048771 78 37 1,000 0,02750924 0,1277663 ! female gonad development GO:0008585 71 37 1,000 0,02750924 0,12752386 ! androgen receptor signaling pathway GO:0030521 81 37 1,000 0,02750924 0,12728233 ! female pregnancy GO:0007565 166 94 2,000 0,02827012 0,13055557 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 1,000 0,02890621 0,13324126 ! embryonic skeletal system morphogenesis GO:0048704 68 38 1,000 0,02890621 0,13299034 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 1,000 0,02890621 0,13274036 ! regulation of protein stability GO:0031647 77 38 1,000 0,02890621 0,13249131 ! glycogen metabolic process GO:0005977 63 38 1,000 0,02890621 0,1322432 ! cellular response to insulin stimulus GO:0032869 85 38 1,000 0,02890621 0,13199602 ! neural tube formation GO:0001841 79 38 1,000 0,02890621 0,13174976 ! sex differentiation GO:0007548 171 96 2,000 0,02983262 0,13571897 ! regulation of T cell activation GO:0050863 175 96 2,000 0,02983262 0,1354667 ! mitotic cell cycle checkpoint GO:0007093 76 39 1,000 0,03033099 0,13747425 ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 1,000 0,03033099 0,13721966 ! glucan metabolic process GO:0044042 64 39 1,000 0,03033099 0,13696602 GO:0006073|cellular glucan metabolic process, ! biogenic amine metabolic process GO:0006576 162 97 2,000 0,03063066 0,13806402 ! mammary gland development GO:0030879 93 40 1,000 0,03178314 0,14299487 ! learning GO:0007612 82 40 1,000 0,03178314 0,14273201 ! development of primary female sexual characteristics GO:0046545 80 40 1,000 0,03178314 0,14247012 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 73 40 1,000 0,03178314 0,14220919 ! regulation of action potential in neuron GO:0019228 80 40 1,000 0,03178314 0,14194921 ! Rho protein signal transduction GO:0007266 88 40 1,000 0,03178314 0,14169018 ! mRNA transport GO:0051028 185 100 2,000 0,03309171 0,14725509 ! RNA export from nucleus GO:0006405 61 41 1,000 0,0332622 0,14774467 ! feeding behavior GO:0007631 69 41 1,000 0,0332622 0,14747653 ! multicellular organismal metabolic process GO:0044236 64 41 1,000 0,0332622 0,14720936 ! mesenchymal cell development GO:0014031 94 41 1,000 0,0332622 0,14694316 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! embryonic epithelial tube formation GO:0001838 85 41 1,000 0,0332622 0,14667792 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 0,03440481 0,15144315 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 0,03440481 0,15117077 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 0,03440481 0,15089937 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,03440481 0,15062894 ! positive regulation of helicase activity GO:0051096 12 5 0,000 0,03440481 0,15035948 ! neuron fate determination GO:0048664 7 5 0,000 0,03440481 0,15009098 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,03440481 0,14982344 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 0,03440481 0,14955685 ! polyol transport GO:0015791 12 5 0,000 0,03440481 0,14929121 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,03440481 0,14902651 ! response to superoxide GO:0000303 10 5 0,000 0,03440481 0,14876274 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,03440481 0,14849991 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 0,03440481 0,14823801 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 0,03440481 0,14797702 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,03440481 0,14771696 ! female meiosis GO:0007143 10 5 0,000 0,03440481 0,14745781 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,03440481 0,14719956 ! hypothalamus development GO:0021854 9 5 0,000 0,03440481 0,14694222 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 0,03440481 0,14668577 ! cobalt ion transport GO:0006824 11 5 0,000 0,03440481 0,14643022 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 0,03440481 0,14617556 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 0,03440481 0,14592179 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,03440481 0,14566889 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,03440481 0,14541687 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 0,03440481 0,14516571 ! selenocysteine incorporation GO:0001514 12 5 0,000 0,03440481 0,14491543 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,03440481 0,14466601 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 0,03440481 0,14441744 ! transposition GO:0032196 9 5 0,000 0,03440481 0,14416972 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 0,03440481 0,14392286 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 0,000 0,03440481 0,14367684 ! negative chemotaxis GO:0050919 16 5 0,000 0,03440481 0,14343165 ! positive regulation of histone modification GO:0031058 6 5 0,000 0,03440481 0,14318731 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,03440481 0,14294379 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 0,03440481 0,1427011 ! behavioral response to pain GO:0048266 10 5 0,000 0,03440481 0,14245924 ! clathrin coat assembly GO:0048268 15 5 0,000 0,03440481 0,14221819 ! Notch receptor processing GO:0007220 11 5 0,000 0,03440481 0,14197795 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,03440481 0,14173853 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 0,03440481 0,14149991 ! micturition GO:0060073 9 5 0,000 0,03440481 0,1412621 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,03440481 0,14102508 ! copulation GO:0007620 9 5 0,000 0,03440481 0,14078886 ! glial cell fate commitment GO:0021781 14 5 0,000 0,03440481 0,14055343 ! protein maturation by protein folding GO:0022417 14 5 0,000 0,03440481 0,14031878 ! bioluminescence GO:0008218 9 5 0,000 0,03440481 0,14008491 ! spermidine metabolic process GO:0008216 7 5 0,000 0,03440481 0,13985183 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,03440481 0,13961952 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,03440481 0,13938798 ! apoptotic cell clearance GO:0043277 23 5 0,000 0,03440481 0,1391572 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,03440481 0,13892719 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 0,03440481 0,13869794 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,03440481 0,13846944 ! grooming behavior GO:0007625 6 5 0,000 0,03440481 0,13824169 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 0,03440481 0,13801469 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,03440481 0,13778844 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 0,03440481 0,13756293 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,03440481 0,13733815 ! response to protozoan GO:0001562 13 5 0,000 0,03440481 0,13711411 ! positive regulation of glycolysis GO:0045821 13 5 0,000 0,03440481 0,1368908 ! lymph vessel development GO:0001945 10 5 0,000 0,03440481 0,13666821 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 0,03440481 0,13644635 ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,03440481 0,1362252 ! single strand break repair GO:0000012 8 5 0,000 0,03440481 0,13600477 ! parathyroid gland development GO:0060017 14 5 0,000 0,03440481 0,13578505 ! anagen GO:0042640 7 5 0,000 0,03440481 0,13556605 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,03440481 0,13534774 ! cytokine secretion GO:0050663 15 5 0,000 0,03440481 0,13513014 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 0,03440481 0,13491324 ! ceramide catabolic process GO:0046514 7 5 0,000 0,03440481 0,13469703 ! skeletal myofibril assembly GO:0014866 12 5 0,000 0,03440481 0,13448152 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,03440481 0,13426669 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,03440481 0,13405255 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,03440481 0,13383909 ! cardiac muscle fiber development GO:0048739 12 5 0,000 0,03440481 0,13362631 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,03440481 0,1334142 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 9 5 0,000 0,03440481 0,13320277 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 0,03440481 0,13299201 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of RNA splicing GO:0033119 6 5 0,000 0,03440481 0,13278191 ! glycine biosynthetic process GO:0006545 7 5 0,000 0,03440481 0,13257247 ! valine metabolic process GO:0006573 12 5 0,000 0,03440481 0,1323637 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 0,03440481 0,13215558 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 0,03440481 0,13194811 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 0,03440481 0,1317413 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 0,03440481 0,13153513 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 0,03440481 0,13132961 ! polyol catabolic process GO:0046174 9 5 0,000 0,03440481 0,13112473 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 0,03440481 0,13092048 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 0,03440481 0,13071687 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 0,03440481 0,1305139 ! muscle cell migration GO:0014812 8 5 0,000 0,03440481 0,13031155 ! mitochondrial fission GO:0000266 8 5 0,000 0,03440481 0,13010983 ! sister chromatid cohesion GO:0007062 15 5 0,000 0,03440481 0,12990873 ! response to tumor necrosis factor GO:0034612 10 5 0,000 0,03440481 0,12970825 ! mRNA transcription GO:0009299 10 5 0,000 0,03440481 0,1295084 ! nerve growth factor processing GO:0032455 9 5 0,000 0,03440481 0,12930915 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 0,03440481 0,12911052 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 0,03440481 0,1289125 ! anaerobic glycolysis GO:0019642 6 5 0,000 0,03440481 0,12871508 ! monocyte activation GO:0042117 10 5 0,000 0,03440481 0,12851827 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,03440481 0,12832206 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,03440481 0,12812645 ! response to food GO:0032094 6 5 0,000 0,03440481 0,12793143 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,03440481 0,127737 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,03440481 0,12754317 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 0,03440481 0,12734992 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,03440481 0,12715726 ! forebrain neuron development GO:0021884 13 5 0,000 0,03440481 0,12696518 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,03440481 0,12677368 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 0,03440481 0,12658275 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 0,03440481 0,1263924 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,03440481 0,12620263 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,03440481 0,12601342 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 0,03440481 0,12582477 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,03440481 0,12563669 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 0,03440481 0,12544918 ! lipid glycosylation GO:0030259 7 5 0,000 0,03440481 0,12526222 ! nucleobase transport GO:0015851 6 5 0,000 0,03440481 0,12507582 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,03440481 0,12488997 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 0,03440481 0,12470467 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 0,03440481 0,12451992 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 0,03440481 0,12433572 ! basic amino acid transport GO:0015802 12 5 0,000 0,03440481 0,12415207 ! cellular glucose homeostasis GO:0001678 6 5 0,000 0,03440481 0,12396895 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 0,03440481 0,12378638 ! actin nucleation GO:0045010 11 5 0,000 0,03440481 0,12360434 ! depurination GO:0045007 5 5 0,000 0,03440481 0,12342283 ! depyrimidination GO:0045008 10 5 0,000 0,03440481 0,12324186 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,03440481 0,12306142 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,03440481 0,1228815 ! G2/M transition checkpoint GO:0031576 8 5 0,000 0,03440481 0,12270212 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,03440481 0,12252325 ! zinc ion homeostasis GO:0055069 9 5 0,000 0,03440481 0,1223449 GO:0006882|cellular zinc ion homeostasis, ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 0,03440481 0,12216708 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,03440481 0,12198977 ! activated T cell proliferation GO:0050798 16 5 0,000 0,03440481 0,12181297 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,03440481 0,12163668 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 0,03440481 0,12146091 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,03440481 0,12128564 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,03440481 0,12111088 ! gamma-delta T cell activation GO:0046629 6 5 0,000 0,03440481 0,12093662 ! response to arsenic GO:0046685 11 5 0,000 0,03440481 0,12076286 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 0,03440481 0,1205896 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,03440481 0,12041683 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 0,03440481 0,12024456 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 0,03440481 0,12007278 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 0,03440481 0,1199015 ! response to mercury ion GO:0046689 8 5 0,000 0,03440481 0,1197307 ! response to cadmium ion GO:0046686 7 5 0,000 0,03440481 0,11956038 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 0,03440481 0,11939055 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 0,03440481 0,1192212 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 0,03440481 0,11905234 ! bile acid biosynthetic process GO:0006699 7 5 0,000 0,03440481 0,11888394 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 0,03440481 0,11871603 ! ganglioside catabolic process GO:0006689 12 5 0,000 0,03440481 0,11854859 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,03440481 0,11838162 ! decidualization GO:0046697 11 5 0,000 0,03440481 0,11821512 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 0,03440481 0,11804909 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 0,03440481 0,11788352 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 0,03440481 0,11771842 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 0,03440481 0,11755377 ! embryonic cleavage GO:0040016 6 5 0,000 0,03440481 0,11738959 ! peroxisome fission GO:0016559 5 5 0,000 0,03440481 0,11722587 ! histone demethylation GO:0016577 13 5 0,000 0,03440481 0,1170626 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 0,03440481 0,11689979 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 0,03440481 0,11673743 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,03440481 0,11657552 ! metaphase plate congression GO:0051310 7 5 0,000 0,03440481 0,11641406 ! regulation of sterol transport GO:0032371 7 5 0,000 0,03440481 0,11625304 GO:0032374|regulation of cholesterol transport, ! enteric nervous system development GO:0048484 8 5 0,000 0,03440481 0,11609247 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 0,03440481 0,11593234 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 0,03440481 0,11577266 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 0,03440481 0,11561341 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,03440481 0,1154546 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 0,03440481 0,11529623 ! B cell homeostasis GO:0001782 13 5 0,000 0,03440481 0,11513829 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,03440481 0,11498078 ! metaphase GO:0051323 11 5 0,000 0,03440481 0,1148237 ! melatonin biosynthetic process GO:0030187 7 5 0,000 0,03440481 0,11466705 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 0,03440481 0,11451083 ! cellular response to nutrient GO:0031670 8 5 0,000 0,03440481 0,11435503 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,03440481 0,11419966 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 0,03440481 0,11404471 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 0,03440481 0,11389017 ! response to redox state GO:0051775 6 5 0,000 0,03440481 0,11373606 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 0,03440481 0,11358236 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 0,03440481 0,11342908 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,03440481 0,11327621 ! brown fat cell differentiation GO:0050873 7 5 0,000 0,03440481 0,11312375 ! regulation of telomerase activity GO:0051972 7 5 0,000 0,03440481 0,11297171 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,03440481 0,11282007 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 0,03440481 0,11266883 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,03440481 0,112518 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 0,03440481 0,11236758 ! striatum development GO:0021756 14 5 0,000 0,03440481 0,11221756 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 0,03440481 0,11206793 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,03440481 0,11191871 ! neural plate morphogenesis GO:0001839 7 5 0,000 0,03440481 0,11176988 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 0,03440481 0,11162145 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,03440481 0,11147341 ! T cell activation during immune response GO:0002286 9 5 0,000 0,03440481 0,11132576 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,03440481 0,1111785 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,03440481 0,11103164 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 0,03440481 0,11088516 ! neuroprotection GO:0043526 8 5 0,000 0,03440481 0,11073906 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,03440481 0,11059335 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,03440481 0,11044803 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,03440481 0,11030308 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 0,03440481 0,11015852 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 0,03440481 0,11001433 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,03440481 0,10987052 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 0,03440481 0,10972709 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,03440481 0,10958403 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 0,03440481 0,10944134 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 0,03440481 0,10929902 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,03440481 0,10915708 ! spindle assembly GO:0051225 6 5 0,000 0,03440481 0,1090155 ! receptor biosynthetic process GO:0032800 7 5 0,000 0,03440481 0,10887429 ! protein palmitoylation GO:0018345 12 5 0,000 0,03440481 0,10873344 ! drug metabolic process GO:0017144 7 5 0,000 0,03440481 0,10859296 ! phospholipid scrambling GO:0017121 8 5 0,000 0,03440481 0,10845284 ! organ regeneration GO:0031100 7 5 0,000 0,03440481 0,10831308 ! carnitine metabolic process GO:0009437 8 5 0,000 0,03440481 0,10817368 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,03440481 0,10803464 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 1,000 0,03476774 0,10903413 ! regulation of T cell differentiation GO:0045580 78 42 1,000 0,03476774 0,10889434 ! positive regulation of transcription factor activity GO:0051091 71 43 1,000 0,03629931 0,11354572 GO:0090047|positive regulation of transcription regulator activity, ! epithelial cell differentiation GO:0030855 83 43 1,000 0,03629931 0,11340052 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 1,000 0,03629931 0,11325569 ! regulation of T cell proliferation GO:0042129 80 43 1,000 0,03629931 0,11311124 ! segmentation GO:0035282 78 43 1,000 0,03629931 0,11296715 ! neuron migration GO:0001764 85 43 1,000 0,03629931 0,11282342 ! regulation of myeloid cell differentiation GO:0045637 105 43 1,000 0,03629931 0,11268006 ! energy reserve metabolic process GO:0006112 76 44 1,000 0,03785648 0,11736469 ! positive regulation of response to external stimulus GO:0032103 88 44 1,000 0,03785648 0,11721593 ! response to reactive oxygen species GO:0000302 75 44 1,000 0,03785648 0,11706756 ! heterocycle biosynthetic process GO:0018130 76 44 1,000 0,03785648 0,11691956 ! receptor-mediated endocytosis GO:0006898 98 45 1,000 0,03943882 0,12165282 ! female gamete generation GO:0007292 71 45 1,000 0,03943882 0,12149941 ! developmental growth GO:0048589 88 45 1,000 0,03943882 0,12134639 ! regulation of actin filament polymerization GO:0030833 99 46 1,000 0,04104591 0,12613226 ! glycolysis GO:0006096 71 46 1,000 0,04104591 0,1259738 ! leukocyte migration GO:0050900 75 46 1,000 0,04104591 0,12581574 ! negative regulation of cell migration GO:0030336 122 46 1,000 0,04104591 0,12565808 ! pigmentation GO:0043473 103 46 1,000 0,04104591 0,12550081 ! positive regulation of protein transport GO:0051222 80 46 1,000 0,04104591 0,12534393 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,04114297 0,1254835 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,04114297 0,12532704 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 0,04114297 0,12517096 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 0,04114297 0,12501528 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,04114297 0,12485998 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 0,04114297 0,12470507 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 0,04114297 0,12455054 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 0,04114297 0,12439639 ! response to oxygen radical GO:0000305 11 6 0,000 0,04114297 0,12424262 ! positive regulation of axon extension GO:0045773 13 6 0,000 0,04114297 0,12408924 ! myoblast cell fate commitment GO:0048625 18 6 0,000 0,04114297 0,12393623 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 0,04114297 0,1237836 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 0,04114297 0,12363134 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,04114297 0,12347946 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,04114297 0,12332796 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 0,04114297 0,12317682 ! forebrain regionalization GO:0021871 9 6 0,000 0,04114297 0,12302605 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,04114297 0,12287565 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,04114297 0,12272562 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 0,04114297 0,12257596 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,04114297 0,12242665 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 0,04114297 0,12227772 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 0,04114297 0,12212914 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,04114297 0,12198093 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 0,04114297 0,12183307 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 0,04114297 0,12168557 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,04114297 0,12153843 ! malate metabolic process GO:0006108 13 6 0,000 0,04114297 0,12139165 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 0,04114297 0,12124522 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 0,04114297 0,12109914 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 0,04114297 0,12095341 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 0,04114297 0,12080803 ! protein refolding GO:0042026 15 6 0,000 0,04114297 0,12066301 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,04114297 0,12051833 ! opsonization GO:0008228 8 6 0,000 0,04114297 0,12037399 ! mating behavior GO:0007617 7 6 0,000 0,04114297 0,12023 ! protein amino acid dealkylation GO:0008214 15 6 0,000 0,04114297 0,12008636 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 0,04114297 0,11994306 GO:0046530|photoreceptor cell differentiation, ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,04114297 0,1198001 ! response to interferon-gamma GO:0034341 16 6 0,000 0,04114297 0,11965748 ! toxin metabolic process GO:0009404 11 6 0,000 0,04114297 0,1195152 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,04114297 0,11937326 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 0,04114297 0,11923165 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 0,04114297 0,11909038 ! cGMP-mediated signaling GO:0019934 14 6 0,000 0,04114297 0,11894945 ! dorsal spinal cord development GO:0021516 10 6 0,000 0,04114297 0,11880885 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 0,04114297 0,11866858 ! thymic T cell selection GO:0045061 16 6 0,000 0,04114297 0,11852864 ! sphingoid catabolic process GO:0046521 8 6 0,000 0,04114297 0,11838903 ! protein lipoylation GO:0009249 10 6 0,000 0,04114297 0,11824975 ! transepithelial chloride transport GO:0030321 12 6 0,000 0,04114297 0,11811079 GO:0070633|transepithelial transport, ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 0,04114297 0,11797216 ! glutamate catabolic process GO:0006538 12 6 0,000 0,04114297 0,11783386 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 0,04114297 0,11769588 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,04114297 0,11755823 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 0,04114297 0,11742089 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,04114297 0,11728388 ! hyperosmotic response GO:0006972 10 6 0,000 0,04114297 0,11714718 ! L-serine biosynthetic process GO:0006564 7 6 0,000 0,04114297 0,11701081 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 0,04114297 0,11687475 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 0,04114297 0,11673901 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,04114297 0,11660358 ! urea metabolic process GO:0019627 7 6 0,000 0,04114297 0,11646846 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,04114297 0,11633366 ! neutrophil activation GO:0042119 7 6 0,000 0,04114297 0,11619917 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,04114297 0,11606499 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 0,04114297 0,11593112 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,04114297 0,11579756 ! paraxial mesoderm development GO:0048339 16 6 0,000 0,04114297 0,11566431 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 0,04114297 0,11553136 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,04114297 0,11539872 ! neuron apoptosis GO:0051402 15 6 0,000 0,04114297 0,11526638 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,04114297 0,11513435 ! T cell mediated immunity GO:0002456 17 6 0,000 0,04114297 0,11500261 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,04114297 0,11487118 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 0,04114297 0,11474005 ! carnitine transport GO:0015879 10 6 0,000 0,04114297 0,11460922 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,04114297 0,11447868 ! positive regulation of exocytosis GO:0045921 11 6 0,000 0,04114297 0,11434845 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 0,04114297 0,1142185 ! 5S class rRNA transcription GO:0042791 13 6 0,000 0,04114297 0,11408886 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! neuronal ion channel clustering GO:0045161 15 6 0,000 0,04114297 0,1139595 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 0,04114297 0,11383045 ! sodium ion homeostasis GO:0055078 12 6 0,000 0,04114297 0,11370168 ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 0,04114297 0,1135732 ! neural nucleus development GO:0048857 19 6 0,000 0,04114297 0,11344502 ! protein targeting to lysosome GO:0006622 12 6 0,000 0,04114297 0,11331712 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,04114297 0,11318951 ! interaction with symbiont GO:0051702 14 6 0,000 0,04114297 0,11306219 ! regulation of dendrite development GO:0050773 16 6 0,000 0,04114297 0,11293515 ! peptidyl-arginine modification GO:0018195 13 6 0,000 0,04114297 0,1128084 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 0,04114297 0,11268193 ! response to copper ion GO:0046688 10 6 0,000 0,04114297 0,11255575 ! response to exogenous dsRNA GO:0043330 13 6 0,000 0,04114297 0,11242985 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,04114297 0,11230423 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 0,04114297 0,11217889 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,04114297 0,11205383 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 0,04114297 0,11192905 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,04114297 0,11180454 ! nucleoside catabolic process GO:0009164 10 6 0,000 0,04114297 0,11168031 ! hair follicle maturation GO:0048820 8 6 0,000 0,04114297 0,11155636 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,04114297 0,11143269 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 0,04114297 0,11130928 ! response to pheromone GO:0019236 6 6 0,000 0,04114297 0,11118615 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 0,04114297 0,1110633 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 0,04114297 0,11094071 ! base conversion or substitution editing GO:0016553 6 6 0,000 0,04114297 0,11081839 ! subpallium development GO:0021544 15 6 0,000 0,04114297 0,11069635 ! neural tube patterning GO:0021532 8 6 0,000 0,04114297 0,11057457 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 0,04114297 0,11045306 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 0,04114297 0,11033181 ! maintenance of organ identity GO:0048496 9 6 0,000 0,04114297 0,11021084 ! G2 phase GO:0051319 16 6 0,000 0,04114297 0,11009012 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 0,04114297 0,10996968 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 0,04114297 0,10984949 ! oxygen homeostasis GO:0032364 10 6 0,000 0,04114297 0,10972957 ! establishment of planar polarity GO:0001736 7 6 0,000 0,04114297 0,10960991 ! regulation of mast cell activation GO:0033003 13 6 0,000 0,04114297 0,1094905 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,04114297 0,10937136 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 0,04114297 0,10925248 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,04114297 0,10913386 ! receptor internalization GO:0031623 11 6 0,000 0,04114297 0,10901549 ! plasminogen activation GO:0031639 9 6 0,000 0,04114297 0,10889738 ! neutrophil homeostasis GO:0001780 11 6 0,000 0,04114297 0,10877953 ! protein deubiquitination GO:0016579 16 6 0,000 0,04114297 0,10866193 ! protein destabilization GO:0031648 9 6 0,000 0,04114297 0,10854458 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 0,04114297 0,10842749 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,04114297 0,10831065 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 0,04114297 0,10819406 ! regulation of viral transcription GO:0046782 11 6 0,000 0,04114297 0,10807772 ! progesterone metabolic process GO:0042448 12 6 0,000 0,04114297 0,10796164 ! negative regulation of axon extension GO:0030517 24 6 0,000 0,04114297 0,1078458 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 0,04114297 0,10773021 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 0,04114297 0,10761486 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,04114297 0,10749977 ! determination of adult lifespan GO:0008340 17 6 0,000 0,04114297 0,10738492 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 0,04114297 0,10727031 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 0,04114297 0,10715595 ! neural plate development GO:0001840 9 6 0,000 0,04114297 0,10704184 ! catecholamine transport GO:0051937 9 6 0,000 0,04114297 0,10692796 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 0,04114297 0,10681433 ! sensory cilium assembly GO:0035058 10 6 0,000 0,04114297 0,10670094 ! organ or tissue specific immune response GO:0002251 8 6 0,000 0,04114297 0,10658779 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 0,04114297 0,10647488 ! maternal placenta development GO:0001893 12 6 0,000 0,04114297 0,1063622 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 0,04114297 0,10624977 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,04114297 0,10613757 ! negative regulation of B cell activation GO:0050869 14 6 0,000 0,04114297 0,10602562 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 0,04114297 0,10591389 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 0,04114297 0,1058024 ! positive regulation of coagulation GO:0050820 13 6 0,000 0,04114297 0,10569115 ! cellular anion homeostasis GO:0030002 11 6 0,000 0,04114297 0,10558013 GO:0055081|anion homeostasis, ! neural tube development GO:0021915 91 47 1,000 0,04267732 0,10940262 ! response to insulin stimulus GO:0032868 98 47 1,000 0,04267732 0,10928794 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 1,000 0,04433265 0,11340803 ! regulation of JAK-STAT cascade GO:0046425 76 48 1,000 0,04433265 0,11328941 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 1,000 0,04433265 0,11317103 ! endosome transport GO:0016197 127 48 1,000 0,04433265 0,11305289 ! positive regulation of DNA binding GO:0043388 83 48 1,000 0,04433265 0,11293501 ! response to calcium ion GO:0051592 94 49 1,000 0,04601149 0,11708965 ! positive regulation of cyclase activity GO:0031281 106 49 1,000 0,04601149 0,11696781 ! regulation of lymphocyte differentiation GO:0045619 92 49 1,000 0,04601149 0,11684622 ! JNK cascade GO:0007254 106 49 1,000 0,04601149 0,11672489 ! protein homooligomerization GO:0051260 84 49 1,000 0,04601149 0,1166038 ! regulation of action potential GO:0001508 102 50 1,000 0,04771342 0,12079159 ! regulation of ossification GO:0030278 123 50 1,000 0,04771342 0,12066655 ! positive regulation of lyase activity GO:0051349 107 50 1,000 0,04771342 0,12054176 ! positive regulation of cytokine production GO:0001819 94 50 1,000 0,04771342 0,12041724 ! tRNA transcription GO:0009304 17 7 0,000 0,0478343 0,12059774 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,0478343 0,12047341 ! regulation of helicase activity GO:0051095 16 7 0,000 0,0478343 0,12034934 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,0478343 0,12022552 ! sleep GO:0030431 16 7 0,000 0,0478343 0,12010196 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,0478343 0,11997865 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 0,0478343 0,1198556 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,0478343 0,11973279 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,0478343 0,11961024 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,0478343 0,11948794 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,0478343 0,11936589 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,0478343 0,11924409 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,0478343 0,11912253 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,0478343 0,11900123 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,0478343 0,11888017 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,0478343 0,11875936 ! SMAD protein complex assembly GO:0007183 13 7 0,000 0,0478343 0,11863879 ! glycolipid transport GO:0046836 11 7 0,000 0,0478343 0,11851847 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,0478343 0,11839839 GO:0051923|sulfation, ! neuron adhesion GO:0007158 14 7 0,000 0,0478343 0,11827855 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,0478343 0,11815895 ! establishment of tissue polarity GO:0007164 8 7 0,000 0,0478343 0,1180396 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 0,0478343 0,11792049 ! mRNA stabilization GO:0048255 18 7 0,000 0,0478343 0,11780162 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 0,0478343 0,11768299 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 0,0478343 0,11756459 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 0,0478343 0,11744644 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 0,0478343 0,11732852 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 0,0478343 0,11721084 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,0478343 0,11709339 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,0478343 0,11697618 ! lipoprotein transport GO:0042953 14 7 0,000 0,0478343 0,11685921 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,0478343 0,11674246 ! rhythmic behavior GO:0007622 17 7 0,000 0,0478343 0,11662595 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 0,0478343 0,11650968 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 0,0478343 0,11639363 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,0478343 0,11627782 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 0,0478343 0,11616223 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,0478343 0,11604688 ! regulation of odontogenesis GO:0042481 14 7 0,000 0,0478343 0,11593175 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,0478343 0,11581685 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 0,0478343 0,11570218 ! mechanosensory behavior GO:0007638 16 7 0,000 0,0478343 0,11558774 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 0,0478343 0,11547352 ! positive regulation of isotype switching GO:0045830 17 7 0,000 0,0478343 0,11535953 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 0,0478343 0,11524577 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,0478343 0,11513222 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,0478343 0,1150189 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,0478343 0,11490581 ! spinal cord patterning GO:0021511 14 7 0,000 0,0478343 0,11479293 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 0,0478343 0,11468028 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,0478343 0,11456785 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,0478343 0,11445564 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 0,0478343 0,11434365 ! cysteine metabolic process GO:0006534 13 7 0,000 0,0478343 0,11423187 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 0,0478343 0,11412032 ! ovulation GO:0030728 10 7 0,000 0,0478343 0,11400898 ! adenohypophysis development GO:0021984 11 7 0,000 0,0478343 0,11389786 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 0,0478343 0,11378696 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 0,0478343 0,11367627 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 0,0478343 0,1135658 ! microtubule nucleation GO:0007020 21 7 0,000 0,0478343 0,11345554 ! proline biosynthetic process GO:0006561 10 7 0,000 0,0478343 0,1133455 ! tryptophan metabolic process GO:0006568 11 7 0,000 0,0478343 0,11323567 ! thyroid hormone generation GO:0006590 13 7 0,000 0,0478343 0,11312605 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 0,0478343 0,11301664 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,0478343 0,11290745 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,0478343 0,11279846 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,0478343 0,11268969 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,0478343 0,11258112 ! galactose metabolic process GO:0006012 13 7 0,000 0,0478343 0,11247277 ! response to dietary excess GO:0002021 8 7 0,000 0,0478343 0,11236462 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,0478343 0,11225668 ! intracellular pH reduction GO:0051452 13 7 0,000 0,0478343 0,11214895 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,0478343 0,11204143 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 0,0478343 0,11193411 ! organ growth GO:0035265 15 7 0,000 0,0478343 0,11182699 ! nucleoside transport GO:0015858 11 7 0,000 0,0478343 0,11172008 ! nucleoside salvage GO:0043174 11 7 0,000 0,0478343 0,11161338 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 0,0478343 0,11150688 ! male sex determination GO:0030238 15 7 0,000 0,0478343 0,11140058 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,0478343 0,11129448 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 0,0478343 0,11118859 ! parturition GO:0007567 16 7 0,000 0,0478343 0,1110829 ! rRNA modification GO:0000154 14 7 0,000 0,0478343 0,1109774 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,0478343 0,11087211 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,0478343 0,11076702 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,0478343 0,11066213 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,0478343 0,11055743 GO:0046676|negative regulation of insulin secretion, ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,0478343 0,11045294 ! G1 DNA damage checkpoint GO:0031571 20 7 0,000 0,0478343 0,11034864 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,0478343 0,11024453 ! fibrinolysis GO:0042730 11 7 0,000 0,0478343 0,11014063 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 0,000 0,0478343 0,11003692 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,0478343 0,1099334 ! eating behavior GO:0042755 8 7 0,000 0,0478343 0,10983008 ! B cell lineage commitment GO:0002326 21 7 0,000 0,0478343 0,10972695 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,0478343 0,10962402 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 0,0478343 0,10952128 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 0,0478343 0,10941873 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,0478343 0,10931638 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 0,0478343 0,10921421 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,0478343 0,10911224 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 0,0478343 0,10901045 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 0,0478343 0,10890886 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 0,0478343 0,10880745 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 0,0478343 0,10870624 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,0478343 0,10860521 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 0,0478343 0,10850437 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,0478343 0,10840372 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,0478343 0,10830325 ! histone ubiquitination GO:0016574 9 7 0,000 0,0478343 0,10820297 ! regulation of meiosis GO:0040020 12 7 0,000 0,0478343 0,10810287 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 0,0478343 0,10800296 ! T cell lineage commitment GO:0002360 16 7 0,000 0,0478343 0,10790324 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 0,0478343 0,1078037 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,0478343 0,10770434 ! membrane to membrane docking GO:0022614 14 7 0,000 0,0478343 0,10760516 ! transcription termination GO:0006353 14 7 0,000 0,0478343 0,10750617 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,0478343 0,10740736 ! anaphase GO:0051322 18 7 0,000 0,0478343 0,10730873 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 0,0478343 0,10721028 ! axonal fasciculation GO:0007413 19 7 0,000 0,0478343 0,10711201 ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 0,0478343 0,10701393 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,0478343 0,10691602 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 0,0478343 0,10681829 ! diuresis GO:0030146 12 7 0,000 0,0478343 0,10672074 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,0478343 0,10662336 ! thiamin metabolic process GO:0006772 7 7 0,000 0,0478343 0,10652617 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,0478343 0,10642915 ! antibiotic transport GO:0042891 9 7 0,000 0,0478343 0,10633231 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 0,0478343 0,10623564 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 0,0478343 0,10613915 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 0,0478343 0,10604284 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,0478343 0,1059467 ! melanin biosynthetic process GO:0042438 10 7 0,000 0,0478343 0,10585073 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 0,0478343 0,10575494 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,0478343 0,10565932 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 0,0478343 0,10556387 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,0478343 0,1054686 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 0,0478343 0,1053735 ! endosome to lysosome transport GO:0008333 12 7 0,000 0,0478343 0,10527856 ! protein modification by small protein removal GO:0070646 19 7 0,000 0,0478343 0,1051838 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 0,0478343 0,10508921 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,0478343 0,10499479 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 0,0478343 0,10490054 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,0478343 0,10480646 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,0478343 0,10471255 ! muscle adaptation GO:0043500 13 7 0,000 0,0478343 0,10461881 ! retina homeostasis GO:0001895 12 7 0,000 0,0478343 0,10452523 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 0,0478343 0,10443182 ! protein amino acid prenylation GO:0018346 19 7 0,000 0,0478343 0,10433858 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 0,0478343 0,1042455 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 0,0478343 0,10415259 ! viral infectious cycle GO:0019058 104 51 1,000 0,04943805 0,10754867 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 1,000 0,04943805 0,10745299 ! negative regulation of immune system process GO:0002683 101 51 1,000 0,04943805 0,10735747 ! morphogenesis of embryonic epithelium GO:0016331 106 52 1,000 0,05118498 0,11105231 ! histone modification GO:0016570 104 52 1,000 0,05118498 0,11095378 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 1,000 0,05118498 0,11085541 ! positive regulation of binding GO:0051099 88 52 1,000 0,05118498 0,11075722 ! Notch signaling pathway GO:0007219 111 52 1,000 0,05118498 0,11065921 ! cellular amino acid biosynthetic process GO:0008652 80 52 1,000 0,05118498 0,11056137 ! vesicle organization GO:0016050 127 53 1,000 0,05295382 0,11428107 ! cartilage development GO:0051216 99 53 1,000 0,05295382 0,11418021 ! synapse organization GO:0050808 102 53 1,000 0,05295382 0,11407952 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,05447913 0,11726212 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,05447913 0,1171589 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 0,05447913 0,11705586 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 0,05447913 0,116953 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,05447913 0,11685032 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,05447913 0,11674782 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,05447913 0,1166455 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,05447913 0,11654335 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,05447913 0,11644139 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,05447913 0,11633961 ! meiotic prophase I GO:0007128 14 8 0,000 0,05447913 0,116238 ! response to zinc ion GO:0010043 12 8 0,000 0,05447913 0,11613657 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,05447913 0,11603532 ! oligopeptide transport GO:0006857 16 8 0,000 0,05447913 0,11593424 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,05447913 0,11583334 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,05447913 0,11573262 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,05447913 0,11563207 ! signal peptide processing GO:0006465 12 8 0,000 0,05447913 0,11553169 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,05447913 0,11543149 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,05447913 0,11533146 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,05447913 0,11523161 ! succinate metabolic process GO:0006105 17 8 0,000 0,05447913 0,11513193 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,05447913 0,11503242 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,05447913 0,11493308 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,05447913 0,11483392 ! estrogen metabolic process GO:0008210 17 8 0,000 0,05447913 0,11473492 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,05447913 0,1146361 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,05447913 0,11453744 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,05447913 0,11443896 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,05447913 0,11434064 ! reflex GO:0060004 17 8 0,000 0,05447913 0,1142425 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,05447913 0,11414452 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,05447913 0,11404671 ! pigment granule organization GO:0048753 17 8 0,000 0,05447913 0,11394907 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,05447913 0,11385159 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,05447913 0,11375428 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,05447913 0,11365714 ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,05447913 0,11356016 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,05447913 0,11346335 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,05447913 0,1133667 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,05447913 0,11327022 ! regulation of pigmentation during development GO:0048070 25 8 0,000 0,05447913 0,1131739 ! melanin metabolic process GO:0006582 17 8 0,000 0,05447913 0,11307775 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,05447913 0,11298176 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,05447913 0,11288593 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,05447913 0,11279026 ! macrophage activation GO:0042116 13 8 0,000 0,05447913 0,11269476 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,05447913 0,11259942 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,05447913 0,11250424 ! positive regulation of insulin secretion GO:0032024 17 8 0,000 0,05447913 0,11240921 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,05447913 0,11231435 ! purine salvage GO:0043101 12 8 0,000 0,05447913 0,11221965 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,05447913 0,11212511 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,05447913 0,11203073 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,05447913 0,11193651 ! osteoblast development GO:0002076 17 8 0,000 0,05447913 0,11184245 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,05447913 0,11174854 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,05447913 0,11165479 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,05447913 0,1115612 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,05447913 0,11146776 ! response to UV-B GO:0010224 17 8 0,000 0,05447913 0,11137449 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,05447913 0,11128136 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,05447913 0,1111884 ! intermediate filament organization GO:0045109 12 8 0,000 0,05447913 0,11109558 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,05447913 0,11100293 ! cellular extravasation GO:0045123 13 8 0,000 0,05447913 0,11091043 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,05447913 0,11081808 ! response to antibiotic GO:0046677 11 8 0,000 0,05447913 0,11072588 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,05447913 0,11063384 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,05447913 0,11054195 ! response to tropane GO:0014073 15 8 0,000 0,05447913 0,11045022 GO:0042220|response to cocaine, ! regulation of T cell differentiation in the thymus GO:0033081 14 8 0,000 0,05447913 0,11035863 ! melanosome transport GO:0032402 13 8 0,000 0,05447913 0,1102672 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,05447913 0,11017592 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,05447913 0,11008479 ! mast cell activation GO:0045576 14 8 0,000 0,05447913 0,10999381 ! multicellular organismal aging GO:0010259 20 8 0,000 0,05447913 0,10990298 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 0,05447913 0,1098123 ! gas homeostasis GO:0033483 14 8 0,000 0,05447913 0,10972177 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,05447913 0,10963139 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,05447913 0,10954116 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,05447913 0,10945108 ! nucleosome disassembly GO:0006337 14 8 0,000 0,05447913 0,10936114 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,05447913 0,10927135 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,05447913 0,10918171 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,05447913 0,10909222 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,05447913 0,10900287 ! intracellular lipid transport GO:0032365 16 8 0,000 0,05447913 0,10891367 ! response to tumor cell GO:0002347 16 8 0,000 0,05447913 0,10882462 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,05447913 0,10873571 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of respiratory burst GO:0060263 12 8 0,000 0,05447913 0,10864695 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,05447913 0,10855833 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 0,05447913 0,10846985 ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,05447913 0,10838152 ! hormone catabolic process GO:0042447 17 8 0,000 0,05447913 0,10829334 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,05447913 0,10820529 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,05447913 0,10811739 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,05447913 0,10802963 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,05447913 0,10794202 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,05447913 0,10785455 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,05447913 0,10776721 ! adult feeding behavior GO:0008343 10 8 0,000 0,05447913 0,10768002 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,05447913 0,10759298 ! ATP catabolic process GO:0006200 11 8 0,000 0,05447913 0,10750607 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,05447913 0,1074193 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,05447913 0,10733267 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,05447913 0,10724618 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,05447913 0,10715983 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,05447913 0,10707362 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,05447913 0,10698755 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,05447913 0,10690161 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,05447913 0,10681582 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 0,05447913 0,10673016 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,05447913 0,10664464 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 0,05447913 0,10655926 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,05447913 0,10647401 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,05447913 0,1063889 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 0,05447913 0,10630392 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 0,05447913 0,10621908 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,05447913 0,10613438 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,05447913 0,10604981 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 0,05447913 0,10596537 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 0,05447913 0,10588107 ! activation of phospholipase C activity GO:0007202 110 54 1,000 0,05474417 0,10631162 GO:0010863|positive regulation of phospholipase C activity, ! membrane fusion GO:0006944 122 54 1,000 0,05474417 0,10622718 ! covalent chromatin modification GO:0016569 115 54 1,000 0,05474417 0,10614287 ! epithelial tube morphogenesis GO:0060562 114 54 1,000 0,05474417 0,1060587 ! positive regulation of phospholipase activity GO:0010518 111 55 1,000 0,05655567 0,10948138 ! regulation of protein polymerization GO:0032271 117 55 1,000 0,05655567 0,10939469 ! negative regulation of cell motion GO:0051271 142 55 1,000 0,05655567 0,10930815 ! glucose catabolic process GO:0006007 88 56 1,000 0,05838792 0,11276023 ! RNA elongation GO:0006354 90 56 1,000 0,05838792 0,11267116 ! regulation of phospholipase activity GO:0010517 113 57 1,000 0,06024055 0,11615443 ! axon extension GO:0048675 16 9 0,000 0,06107777 0,11767585 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,06107777 0,11758312 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,06107777 0,11749054 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 0,06107777 0,1173981 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,06107777 0,1173058 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,06107777 0,11721365 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,06107777 0,11712165 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,06107777 0,11702979 ! reproductive behavior GO:0019098 22 9 0,000 0,06107777 0,11693807 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,06107777 0,1168465 ! Golgi to endosome transport GO:0006895 25 9 0,000 0,06107777 0,11675507 ! UTP metabolic process GO:0046051 10 9 0,000 0,06107777 0,11666379 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,06107777 0,11657264 ! induction of positive chemotaxis GO:0050930 17 9 0,000 0,06107777 0,11648164 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,06107777 0,11639078 ! regulation of histone modification GO:0031056 14 9 0,000 0,06107777 0,11630006 ! regulation of glycolysis GO:0006110 20 9 0,000 0,06107777 0,11620949 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,06107777 0,11611905 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,06107777 0,11602876 ! chemosensory behavior GO:0007635 21 9 0,000 0,06107777 0,1159386 ! microtubule bundle formation GO:0001578 22 9 0,000 0,06107777 0,11584859 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,06107777 0,11575871 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,06107777 0,11566898 ! leukocyte degranulation GO:0043299 16 9 0,000 0,06107777 0,11557938 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,06107777 0,11548992 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,06107777 0,1154006 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,06107777 0,11531142 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,06107777 0,11522238 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,06107777 0,11513347 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,06107777 0,1150447 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,06107777 0,11495607 ! protein targeting to ER GO:0045047 25 9 0,000 0,06107777 0,11486758 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,06107777 0,11477922 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 0,06107777 0,11469099 ! T cell selection GO:0045058 27 9 0,000 0,06107777 0,1146029 ! glycine catabolic process GO:0006546 15 9 0,000 0,06107777 0,11451495 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,06107777 0,11442713 ! endosome organization GO:0007032 20 9 0,000 0,06107777 0,11433945 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,06107777 0,1142519 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,06107777 0,11416448 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,06107777 0,1140772 ! mannose metabolic process GO:0006013 13 9 0,000 0,06107777 0,11399005 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,06107777 0,11390304 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,06107777 0,11381616 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,06107777 0,11372941 ! receptor clustering GO:0043113 20 9 0,000 0,06107777 0,11364279 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,06107777 0,1135563 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,06107777 0,11346995 ! retinol metabolic process GO:0042572 20 9 0,000 0,06107777 0,11338372 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,06107777 0,11329763 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,06107777 0,11321167 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,06107777 0,11312584 ! oligodendrocyte development GO:0014003 11 9 0,000 0,06107777 0,11304014 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 0,06107777 0,11295457 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,06107777 0,11286912 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,06107777 0,11278381 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,06107777 0,11269863 ! response to amine stimulus GO:0014075 13 9 0,000 0,06107777 0,11261357 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,06107777 0,11252864 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,06107777 0,11244384 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,06107777 0,11235917 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,06107777 0,11227463 ! renal water homeostasis GO:0003091 15 9 0,000 0,06107777 0,11219021 ! postreplication repair GO:0006301 25 9 0,000 0,06107777 0,11210592 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,06107777 0,11202176 ! icosanoid secretion GO:0032309 15 9 0,000 0,06107777 0,11193772 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,06107777 0,11185381 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,06107777 0,11177002 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,06107777 0,11168636 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,06107777 0,11160283 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,06107777 0,11151942 ! sterol catabolic process GO:0016127 14 9 0,000 0,06107777 0,11143613 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,06107777 0,11135297 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,06107777 0,11126993 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,06107777 0,11118702 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,06107777 0,11110423 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 0,06107777 0,11102156 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,06107777 0,11093902 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 0,06107777 0,1108566 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,06107777 0,1107743 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,06107777 0,11069212 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,06107777 0,11061007 ! purine base metabolic process GO:0006144 25 9 0,000 0,06107777 0,11052813 ! pigment granule transport GO:0051904 17 9 0,000 0,06107777 0,11044632 ! regulation of telomere maintenance GO:0032204 17 9 0,000 0,06107777 0,11036463 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,06107777 0,11028306 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,06107777 0,11020161 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,06107777 0,11012028 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,06107777 0,11003907 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,06107777 0,10995798 ! mitochondrion localization GO:0051646 18 9 0,000 0,06107777 0,10987701 ! cellular polysaccharide metabolic process GO:0044264 93 58 1,000 0,06211319 0,11165749 ! sulfur compound biosynthetic process GO:0044272 108 58 1,000 0,06211319 0,11157539 ! aging GO:0007568 112 58 1,000 0,06211319 0,11149341 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 1,000 0,06211319 0,11141155 ! positive regulation of lipase activity GO:0060193 115 58 1,000 0,06211319 0,11132981 ! nuclear export GO:0051168 110 59 1,000 0,06400548 0,11463738 ! lipid modification GO:0030258 112 60 1,000 0,06591705 0,11797462 ! DNA catabolic process GO:0006308 94 60 1,000 0,06591705 0,11788825 ! heterocycle catabolic process GO:0046700 100 60 1,000 0,06591705 0,11780201 ! adult behavior GO:0030534 104 60 1,000 0,06591705 0,1177159 ! kidney development GO:0001822 133 60 1,000 0,06591705 0,11762991 ! regulation of developmental growth GO:0048638 16 10 0,000 0,06763054 0,12059956 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,06763054 0,1205116 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,06763054 0,12042376 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,06763054 0,12033605 ! associative learning GO:0008306 21 10 0,000 0,06763054 0,12024847 ! phosphate transport GO:0006817 24 10 0,000 0,06763054 0,12016102 ! cell volume homeostasis GO:0006884 17 10 0,000 0,06763054 0,12007369 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,06763054 0,11998649 ! CTP metabolic process GO:0046036 11 10 0,000 0,06763054 0,11989942 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,06763054 0,11981247 ! GTP metabolic process GO:0046039 11 10 0,000 0,06763054 0,11972565 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,06763054 0,11963896 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,06763054 0,11955239 ! social behavior GO:0035176 29 10 0,000 0,06763054 0,11946594 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,06763054 0,11937962 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,06763054 0,11929343 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,06763054 0,11920736 ! androgen metabolic process GO:0008209 17 10 0,000 0,06763054 0,11912141 ! phospholipid efflux GO:0033700 19 10 0,000 0,06763054 0,11903559 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,06763054 0,11894989 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,06763054 0,11886432 ! lung alveolus development GO:0048286 26 10 0,000 0,06763054 0,11877886 ! pathogenesis GO:0009405 17 10 0,000 0,06763054 0,11869353 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,06763054 0,11860833 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,06763054 0,11852324 ! endoderm development GO:0007492 18 10 0,000 0,06763054 0,11843828 ! arginine catabolic process GO:0006527 17 10 0,000 0,06763054 0,11835344 ! proline metabolic process GO:0006560 13 10 0,000 0,06763054 0,11826872 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,06763054 0,11818412 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 0,06763054 0,11809964 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,06763054 0,11801529 ! V(D)J recombination GO:0033151 34 10 0,000 0,06763054 0,11793105 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,06763054 0,11784693 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,06763054 0,11776294 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,06763054 0,11767906 ! B cell proliferation GO:0042100 19 10 0,000 0,06763054 0,1175953 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,06763054 0,11751166 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,06763054 0,11742815 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,06763054 0,11734474 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,06763054 0,11726146 ! ruffle organization GO:0031529 17 10 0,000 0,06763054 0,1171783 ! epithelial cell development GO:0002064 21 10 0,000 0,06763054 0,11709525 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,06763054 0,11701232 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,06763054 0,11692951 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,06763054 0,11684682 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,06763054 0,11676424 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,06763054 0,11668178 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,06763054 0,11659944 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 22 10 0,000 0,06763054 0,11651721 ! copper ion homeostasis GO:0055070 13 10 0,000 0,06763054 0,1164351 ! protein heterooligomerization GO:0051291 17 10 0,000 0,06763054 0,1163531 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,06763054 0,11627122 ! segment specification GO:0007379 15 10 0,000 0,06763054 0,11618945 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,06763054 0,1161078 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 0,000 0,06763054 0,11602626 ! blastoderm segmentation GO:0007350 19 10 0,000 0,06763054 0,11594484 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,06763054 0,11586353 ! response to dsRNA GO:0043331 23 10 0,000 0,06763054 0,11578234 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,06763054 0,11570126 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,06763054 0,11562029 ! melanosome localization GO:0032400 16 10 0,000 0,06763054 0,11553944 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,06763054 0,1154587 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,06763054 0,11537807 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,06763054 0,11529756 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,06763054 0,11521716 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,06763054 0,11513686 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,06763054 0,11505669 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,06763054 0,11497662 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,06763054 0,11489666 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,06763054 0,11481682 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,06763054 0,11473708 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,06763054 0,11465746 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,06763054 0,11457795 ! midbrain development GO:0030901 14 10 0,000 0,06763054 0,11449855 ! musculoskeletal movement GO:0050881 16 10 0,000 0,06763054 0,11441925 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,06763054 0,11434007 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,06763054 0,114261 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,06763054 0,11418203 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,06763054 0,11410318 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,06763054 0,11402443 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,06763054 0,11394579 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 0,000 0,06763054 0,11386726 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 24 10 0,000 0,06763054 0,11378884 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,06763054 0,11371053 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,06763054 0,11363233 ! cerebellar cortex development GO:0021695 16 10 0,000 0,06763054 0,11355423 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,06763054 0,11347624 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,06763054 0,11339835 ! response to nicotine GO:0035094 20 10 0,000 0,06763054 0,11332058 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,06763054 0,11324291 ! regulation of heart contraction GO:0008016 123 61 1,000 0,06784754 0,11352845 ! negative regulation of response to stimulus GO:0048585 106 61 1,000 0,06784754 0,11345075 ! viral reproductive process GO:0022415 132 62 1,000 0,0697966 0,11663002 ! DNA damage response, signal transduction GO:0042770 136 62 1,000 0,0697966 0,1165503 ! response to peptide hormone stimulus GO:0043434 129 64 1,000 0,07374902 0,12306616 ! respiratory burst GO:0045730 17 11 0,000 0,07413776 0,12363041 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,07413776 0,12354607 ! neuron fate specification GO:0048665 18 11 0,000 0,07413776 0,12346186 ! telencephalon cell migration GO:0022029 23 11 0,000 0,07413776 0,12337775 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,07413776 0,12329377 ! synapsis GO:0007129 14 11 0,000 0,07413776 0,12320989 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,07413776 0,12312613 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,07413776 0,12304249 ! response to pain GO:0048265 27 11 0,000 0,07413776 0,12295896 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,07413776 0,12287554 ! keratinocyte proliferation GO:0043616 19 11 0,000 0,07413776 0,12279223 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 0,000 0,07413776 0,12270904 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 23 11 0,000 0,07413776 0,12262596 ! bone resorption GO:0045453 16 11 0,000 0,07413776 0,12254299 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,07413776 0,12246014 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,07413776 0,12237739 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,07413776 0,12229476 ! melanocyte differentiation GO:0030318 20 11 0,000 0,07413776 0,12221224 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 20 11 0,000 0,07413776 0,12212983 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,07413776 0,12204754 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,07413776 0,12196535 ! regulation of intracellular pH GO:0051453 21 11 0,000 0,07413776 0,12188327 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,07413776 0,12180131 ! UV protection GO:0009650 20 11 0,000 0,07413776 0,12171945 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,07413776 0,12163771 ! macroautophagy GO:0016236 19 11 0,000 0,07413776 0,12155607 ! temperature homeostasis GO:0001659 18 11 0,000 0,07413776 0,12147454 ! behavioral fear response GO:0001662 27 11 0,000 0,07413776 0,12139313 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,07413776 0,12131182 ! negative regulation of ossification GO:0030279 27 11 0,000 0,07413776 0,12123062 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,07413776 0,12114953 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,07413776 0,12106855 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 0,07413776 0,12098767 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,07413776 0,12090691 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,07413776 0,12082625 ! regulation of organ growth GO:0046620 14 11 0,000 0,07413776 0,1207457 ! pigment granule localization GO:0051875 20 11 0,000 0,07413776 0,12066525 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,07413776 0,12058492 ! vasoconstriction GO:0042310 20 11 0,000 0,07413776 0,12050469 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,07413776 0,12042456 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,07413776 0,12034455 ! embryonic axis specification GO:0000578 19 11 0,000 0,07413776 0,12026464 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,07413776 0,12018483 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,07413776 0,12010514 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,07413776 0,12002554 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,07413776 0,11994606 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,07413776 0,11986667 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,07413776 0,1197874 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,07413776 0,11970822 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,07413776 0,11962916 ! prophase GO:0051324 17 11 0,000 0,07413776 0,11955019 ! neuroblast proliferation GO:0007405 25 11 0,000 0,07413776 0,11947134 ! nucleosome positioning GO:0016584 15 11 0,000 0,07413776 0,11939258 ! regulation of isotype switching GO:0045191 24 11 0,000 0,07413776 0,11931393 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,07413776 0,11923538 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,07413776 0,11915694 ! apical protein localization GO:0045176 18 11 0,000 0,07413776 0,1190786 ! acid secretion GO:0046717 20 11 0,000 0,07413776 0,11900036 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,07413776 0,11892222 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,07413776 0,11884419 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,07413776 0,11876626 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,07413776 0,11868843 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,07413776 0,1186107 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! cholesterol efflux GO:0033344 21 11 0,000 0,07413776 0,11853308 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,07413776 0,11845556 ! negative regulation of glucose import GO:0046325 18 11 0,000 0,07413776 0,11837813 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 26 11 0,000 0,07413776 0,11830081 ! embryonic gut development GO:0048566 19 11 0,000 0,07413776 0,11822359 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,07413776 0,11814647 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,07413776 0,11806946 ! activation of innate immune response GO:0002218 16 11 0,000 0,07413776 0,11799254 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,07413776 0,11791572 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,07413776 0,117839 ! lysogeny GO:0030069 22 11 0,000 0,07413776 0,11776238 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,07413776 0,11768586 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,07413776 0,11760944 ! sequestering of metal ion GO:0051238 15 11 0,000 0,07413776 0,11753312 ! regulation of embryonic development GO:0045995 35 11 0,000 0,07413776 0,1174569 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 1,000 0,07575169 0,11993609 ! multicellular organism reproduction GO:0032504 123 65 1,000 0,07575169 0,11985841 GO:0048609|reproductive process in a multicellular organism, ! gonad development GO:0008406 115 66 1,000 0,07777156 0,1229747 ! embryonic limb morphogenesis GO:0030326 139 67 1,000 0,07980827 0,12611359 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 1,000 0,07980827 0,12603207 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,08059975 0,12719973 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,08059975 0,12711761 ! positive regulation of cellular catabolic process GO:0031331 34 12 0,000 0,08059975 0,1270356 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,08059975 0,1269537 ! virus-host interaction GO:0019048 30 12 0,000 0,08059975 0,1268719 ! regulation of positive chemotaxis GO:0050926 22 12 0,000 0,08059975 0,1267902 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,08059975 0,12670861 ! protein complex disassembly GO:0043241 28 12 0,000 0,08059975 0,12662713 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,08059975 0,12654575 ! hippocampus development GO:0021766 29 12 0,000 0,08059975 0,12646447 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 0,000 0,08059975 0,1263833 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,08059975 0,12630223 ! T cell proliferation GO:0042098 32 12 0,000 0,08059975 0,12622127 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,08059975 0,12614041 ! ventral spinal cord development GO:0021517 25 12 0,000 0,08059975 0,12605966 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,08059975 0,125979 ! drug transport GO:0015893 16 12 0,000 0,08059975 0,12589845 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,08059975 0,12581801 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,08059975 0,12573766 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,08059975 0,12565742 ! polyamine metabolic process GO:0006595 18 12 0,000 0,08059975 0,12557728 ! focal adhesion formation GO:0048041 37 12 0,000 0,08059975 0,12549725 ! mitotic spindle organization GO:0007052 23 12 0,000 0,08059975 0,12541731 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,08059975 0,12533748 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,08059975 0,12525775 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,08059975 0,12517812 ! lipid digestion GO:0044241 21 12 0,000 0,08059975 0,12509859 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,08059975 0,12501916 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,08059975 0,12493984 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,08059975 0,12486061 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,08059975 0,12478148 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,08059975 0,12470246 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,08059975 0,12462353 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,08059975 0,12454471 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,08059975 0,12446598 ! snRNA metabolic process GO:0016073 30 12 0,000 0,08059975 0,12438735 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,08059975 0,12430883 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,08059975 0,1242304 ! cranial nerve development GO:0021545 23 12 0,000 0,08059975 0,12415207 ! fucose catabolic process GO:0019317 25 12 0,000 0,08059975 0,12407384 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,08059975 0,12399571 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,08059975 0,12391767 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 0,08059975 0,12383974 ! zymogen activation GO:0031638 18 12 0,000 0,08059975 0,1237619 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,08059975 0,12368416 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,08059975 0,12360652 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,08059975 0,12352897 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,08059975 0,12345152 ! negative regulation of mast cell proliferation GO:0070667 24 12 0,000 0,08059975 0,12337417 GO:0042130|negative regulation of T cell proliferation, ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,08059975 0,12329692 ! defense response to fungus GO:0050832 15 12 0,000 0,08059975 0,12321976 ! response to cold GO:0009409 17 12 0,000 0,08059975 0,1231427 ! establishment of cell polarity GO:0030010 21 12 0,000 0,08059975 0,12306574 ! regulation of synapse organization GO:0050807 18 12 0,000 0,08059975 0,12298887 ! regulation of cellular response to stress GO:0080135 142 68 1,000 0,08186151 0,12483625 ! hexose catabolic process GO:0019320 113 68 1,000 0,08186151 0,12475838 ! negative regulation of ligase activity GO:0051352 116 68 1,000 0,08186151 0,1246806 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! viral reproduction GO:0016032 142 68 1,000 0,08186151 0,12460292 ! regulation of lipase activity GO:0060191 137 68 1,000 0,08186151 0,12452533 ! adaptive immune response GO:0002250 126 68 1,000 0,08186151 0,12444784 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 1,000 0,08393095 0,12751449 ! cellular amino acid catabolic process GO:0009063 120 69 1,000 0,08393095 0,12743524 ! single fertilization GO:0007338 83 69 1,000 0,08393095 0,12735609 ! germ cell development GO:0007281 133 70 1,000 0,08601625 0,1304393 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,08701682 0,13187474 ! cGMP metabolic process GO:0046068 18 13 0,000 0,08701682 0,13179298 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,08701682 0,13171133 ! peroxisomal transport GO:0043574 28 13 0,000 0,08701682 0,13162977 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,08701682 0,13154832 ! cartilage condensation GO:0001502 22 13 0,000 0,08701682 0,13146696 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,08701682 0,13138571 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,08701682 0,13130456 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,08701682 0,13122351 ! endocrine pancreas development GO:0031018 25 13 0,000 0,08701682 0,13114255 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,08701682 0,1310617 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,08701682 0,13098095 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,08701682 0,1309003 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,08701682 0,13081974 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,08701682 0,13073929 ! plasma membrane organization GO:0007009 27 13 0,000 0,08701682 0,13065893 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,08701682 0,13057867 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,08701682 0,13049851 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,08701682 0,13041845 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,08701682 0,13033849 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! cytokine metabolic process GO:0042107 24 13 0,000 0,08701682 0,13025863 ! asymmetric protein localization GO:0008105 24 13 0,000 0,08701682 0,13017886 ! monoamine transport GO:0015844 21 13 0,000 0,08701682 0,13009919 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 0,000 0,08701682 0,13001962 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! L-glutamate transport GO:0015813 30 13 0,000 0,08701682 0,12994015 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,08701682 0,12986077 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,08701682 0,12978149 ! protein homotetramerization GO:0051289 24 13 0,000 0,08701682 0,12970231 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,08701682 0,12962322 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,08701682 0,12954423 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,08701682 0,12946533 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,08701682 0,12938654 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,08701682 0,12930783 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,08701682 0,12922923 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,08701682 0,12915072 ! histone methylation GO:0016571 29 13 0,000 0,08701682 0,1290723 ! chromatin silencing GO:0006342 29 13 0,000 0,08701682 0,12899398 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,08701682 0,12891575 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,08701682 0,12883762 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,08701682 0,12875959 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,08701682 0,12868165 ! regulation of mRNA stability GO:0043488 32 13 0,000 0,08701682 0,1286038 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,08701682 0,12852605 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,08701682 0,12844839 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,08701682 0,12837082 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,08701682 0,12829335 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,08701682 0,12821597 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,08701682 0,12813869 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,08701682 0,12806149 ! insulin secretion GO:0030073 24 13 0,000 0,08701682 0,12798439 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,08701682 0,12790739 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 0,08701682 0,12783047 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,08701682 0,12775365 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,08701682 0,12767692 ! cell cycle checkpoint GO:0000075 145 71 1,000 0,08811711 0,12921375 ! appendage morphogenesis GO:0035107 150 72 1,000 0,0902332 0,13223738 GO:0035108|limb morphogenesis, ! actin filament organization GO:0007015 167 72 1,000 0,0902332 0,13215811 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 1,000 0,0902332 0,13207892 ! coenzyme biosynthetic process GO:0009108 119 72 1,000 0,0902332 0,13199983 ! appendage development GO:0048736 151 73 1,000 0,09236422 0,13503638 GO:0060173|limb development, ! rRNA transcription GO:0009303 28 14 0,000 0,09338927 0,13645335 ! water transport GO:0006833 21 14 0,000 0,09338927 0,13637178 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,09338927 0,13629032 ! non-recombinational repair GO:0000726 29 14 0,000 0,09338927 0,13620895 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,09338927 0,13612768 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,09338927 0,13604651 ! RNA polyadenylation GO:0043631 32 14 0,000 0,09338927 0,13596543 ! lipid localization GO:0010876 32 14 0,000 0,09338927 0,13588445 GO:0019915|lipid storage, ! regulated secretory pathway GO:0045055 24 14 0,000 0,09338927 0,13580357 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,09338927 0,13572278 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,09338927 0,13564209 ! arginine metabolic process GO:0006525 21 14 0,000 0,09338927 0,13556149 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,09338927 0,135481 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,09338927 0,13540059 ! regulation of heart rate GO:0002027 25 14 0,000 0,09338927 0,13532028 ! fear response GO:0042596 34 14 0,000 0,09338927 0,13524007 ! organic alcohol transport GO:0015850 29 14 0,000 0,09338927 0,13515995 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,09338927 0,13507993 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 0,000 0,09338927 0,135 GO:0060675|ureteric bud morphogenesis, ! neutral amino acid transport GO:0015804 28 14 0,000 0,09338927 0,13492016 ! bone mineralization GO:0030282 18 14 0,000 0,09338927 0,13484042 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,09338927 0,13476078 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,09338927 0,13468123 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,09338927 0,13460177 ! regulation of cellular pH GO:0030641 27 14 0,000 0,09338927 0,1345224 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,09338927 0,13444313 ! ribosome assembly GO:0042255 18 14 0,000 0,09338927 0,13436396 ! cerebellum development GO:0021549 23 14 0,000 0,09338927 0,13428487 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,09338927 0,13420588 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,09338927 0,13412698 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,09338927 0,13404818 ! NADP metabolic process GO:0006739 24 14 0,000 0,09338927 0,13396946 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,09338927 0,13389084 ! oxygen transport GO:0015671 22 14 0,000 0,09338927 0,13381231 ! male genitalia development GO:0030539 26 14 0,000 0,09338927 0,13373388 ! regulation of RNA stability GO:0043487 33 14 0,000 0,09338927 0,13365553 ! regulation of axon extension GO:0030516 43 14 0,000 0,09338927 0,13357728 ! release of cytochrome c from mitochondria GO:0001836 31 14 0,000 0,09338927 0,13349912 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,09338927 0,13342105 ! phosphoinositide-mediated signaling GO:0048015 141 75 1,000 0,09666978 0,13802705 ! leukocyte mediated immunity GO:0002443 136 75 1,000 0,09666978 0,13794642 ! rhythmic process GO:0048511 142 75 1,000 0,09666978 0,1378659 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,09971743 0,14212934 ! lactation GO:0007595 30 15 0,000 0,09971743 0,14204646 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,09971743 0,14196369 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,09971743 0,14188101 ! superoxide anion generation GO:0042554 22 15 0,000 0,09971743 0,14179842 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,09971743 0,14171593 ! negative regulation of bone remodeling GO:0046851 34 15 0,000 0,09971743 0,14163354 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,09971743 0,14155124 ! copper ion transport GO:0006825 22 15 0,000 0,09971743 0,14146904 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,09971743 0,14138693 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,09971743 0,14130492 ! sulfate transport GO:0008272 27 15 0,000 0,09971743 0,14122301 ! response to cAMP GO:0051591 25 15 0,000 0,09971743 0,14114119 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,09971743 0,14105946 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,09971743 0,14097783 ! response to hexose stimulus GO:0009746 25 15 0,000 0,09971743 0,14089629 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,09971743 0,14081485 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,09971743 0,1407335 ! vesicle coating GO:0006901 38 15 0,000 0,09971743 0,14065224 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 0,09971743 0,14057108 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 0,09971743 0,14049002 ! regulation of exocytosis GO:0017157 26 15 0,000 0,09971743 0,14040904 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,09971743 0,14032816 ! G1/S transition checkpoint GO:0031575 37 15 0,000 0,09971743 0,14024737 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,09971743 0,14016668 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,09971743 0,14008608 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,09971743 0,14000557 ! regulation of vasodilation GO:0042312 27 15 0,000 0,09971743 0,13992515 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,09971743 0,13984483 ! histone deacetylation GO:0016575 24 15 0,000 0,09971743 0,13976459 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,09971743 0,13968445 ! water homeostasis GO:0030104 28 15 0,000 0,09971743 0,1396044 ! cofactor transport GO:0051181 30 15 0,000 0,09971743 0,13952445 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,09971743 0,13944458 ! muscle maintenance GO:0046716 26 15 0,000 0,09971743 0,13936481 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,09971743 0,13928513 ! intestinal absorption GO:0050892 31 15 0,000 0,09971743 0,13920553 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,09971743 0,13912603 ! heme biosynthetic process GO:0006783 33 15 0,000 0,09971743 0,13904662 ! cell killing GO:0001906 32 15 0,000 0,09971743 0,13896731 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,09971743 0,13888808 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,09971743 0,13880894 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,09971743 0,13872989 ! actin filament polymerization GO:0030041 27 15 0,000 0,09971743 0,13865093 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,09971743 0,13857206 ! amine catabolic process GO:0009310 136 77 1,000 0,10103137 0,14031816 ! phosphoinositide metabolic process GO:0030384 146 77 1,000 0,10103137 0,14023843 ! positive regulation of ligase activity GO:0051351 130 77 1,000 0,10103137 0,14015879 ! monosaccharide catabolic process GO:0046365 125 77 1,000 0,10103137 0,14007925 ! fertilization GO:0009566 99 78 1,000 0,10323243 0,14304982 ! protein oligomerization GO:0051259 149 79 1,000 0,10544661 0,14603518 ! regulation of synaptic transmission GO:0050804 159 79 1,000 0,10544661 0,14595244 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,1060016 0,14663754 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,1060016 0,14655456 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,1060016 0,14647166 ! bone remodeling GO:0046849 28 16 0,000 0,1060016 0,14638886 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,1060016 0,14630616 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,1060016 0,14622355 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,1060016 0,14614103 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,1060016 0,1460586 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,1060016 0,14597627 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,1060016 0,14589403 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,1060016 0,14581188 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,1060016 0,14572983 ! protein polyubiquitination GO:0000209 41 16 0,000 0,1060016 0,14564786 ! glutamate metabolic process GO:0006536 25 16 0,000 0,1060016 0,14556599 ! pituitary gland development GO:0021983 30 16 0,000 0,1060016 0,14548421 ! response to osmotic stress GO:0006970 27 16 0,000 0,1060016 0,14540253 ! lysosomal transport GO:0007041 31 16 0,000 0,1060016 0,14532093 ! fructose metabolic process GO:0006000 25 16 0,000 0,1060016 0,14523943 ! L-amino acid transport GO:0015807 33 16 0,000 0,1060016 0,14515802 ! stem cell development GO:0048864 46 16 0,000 0,1060016 0,14507669 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,1060016 0,14499546 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 36 16 0,000 0,1060016 0,14491433 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,1060016 0,14483328 ! axon cargo transport GO:0008088 46 16 0,000 0,1060016 0,14475232 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,1060016 0,14467145 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,1060016 0,14459068 ! positive regulation of protein import into nucleus GO:0042307 34 16 0,000 0,1060016 0,14450999 ! DNA replication initiation GO:0006270 28 16 0,000 0,1060016 0,14442939 ! neuron recognition GO:0008038 40 16 0,000 0,1060016 0,14434889 ! mRNA splice site selection GO:0006376 44 16 0,000 0,1060016 0,14426847 ! tissue regeneration GO:0042246 27 16 0,000 0,1060016 0,14418814 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,1060016 0,1441079 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,1060016 0,14402775 ! negative regulation of tissue remodeling GO:0034104 37 16 0,000 0,1060016 0,14394769 ! biomineral formation GO:0031214 22 16 0,000 0,1060016 0,14386772 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,1060016 0,14378784 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,1060016 0,14370805 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,1060016 0,14362834 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,1060016 0,14354872 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,1060016 0,1434692 ! negative regulation of leukocyte proliferation GO:0070664 32 16 0,000 0,1060016 0,14338976 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! peptide hormone processing GO:0016486 27 16 0,000 0,1060016 0,1433104 ! development of primary sexual characteristics GO:0045137 143 80 1,000 0,10767362 0,1454904 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 1,000 0,10991317 0,14843443 ! protein import into nucleus GO:0006606 174 82 1,000 0,112165 0,15139176 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,11224207 0,15141214 ! metencephalon development GO:0022037 32 17 0,000 0,11224207 0,15132858 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,11224207 0,15124511 ! endothelial cell migration GO:0043542 31 17 0,000 0,11224207 0,15116173 ! gene silencing by RNA GO:0031047 38 17 0,000 0,11224207 0,15107845 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,11224207 0,15099525 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,11224207 0,15091215 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,11224207 0,15082914 ! myoblast differentiation GO:0045445 50 17 0,000 0,11224207 0,15074622 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 0,000 0,11224207 0,1506634 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,11224207 0,15058066 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,11224207 0,15049801 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,11224207 0,15041546 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,11224207 0,15033299 ! negative regulation of microtubule depolymerization GO:0007026 50 17 0,000 0,11224207 0,15025062 GO:0031114|regulation of microtubule depolymerization, ! NAD metabolic process GO:0019674 33 17 0,000 0,11224207 0,15016834 ! membrane budding GO:0006900 42 17 0,000 0,11224207 0,15008614 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,11224207 0,15000404 ! regulation of protein binding GO:0043393 33 17 0,000 0,11224207 0,14992202 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,11224207 0,1498401 ! genitalia development GO:0048806 32 17 0,000 0,11224207 0,14975826 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,11224207 0,14967652 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 0,000 0,11224207 0,14959486 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,11224207 0,14951329 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,11224207 0,14943182 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,11224207 0,14935043 ! steroid catabolic process GO:0006706 34 17 0,000 0,11224207 0,14926912 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,11224207 0,14918791 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,11224207 0,14910679 ! gas transport GO:0015669 26 17 0,000 0,11224207 0,14902575 ! organic cation transport GO:0015695 32 17 0,000 0,11224207 0,1489448 ! negative regulation of homeostatic process GO:0032845 36 17 0,000 0,11224207 0,14886394 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,11224207 0,14878317 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,11224207 0,14870248 ! regulation of adenylate cyclase activity GO:0045761 165 83 1,000 0,1144288 0,15151738 ! nuclear import GO:0051170 177 83 1,000 0,1144288 0,1514353 ! response to metal ion GO:0010038 158 84 1,000 0,11670432 0,15436311 ! response to nutrient GO:0007584 135 84 1,000 0,11670432 0,15427958 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,11843916 0,1564883 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,11843916 0,15640371 ! limbic system development GO:0021761 40 18 0,000 0,11843916 0,15631922 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,11843916 0,15623481 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,11843916 0,1561505 ! adult walking behavior GO:0007628 36 18 0,000 0,11843916 0,15606627 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,11843916 0,15598214 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,11843916 0,1558981 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,11843916 0,15581415 ! glycine metabolic process GO:0006544 30 18 0,000 0,11843916 0,15573028 ! glutamine metabolic process GO:0006541 29 18 0,000 0,11843916 0,15564651 ! response to retinoic acid GO:0032526 31 18 0,000 0,11843916 0,15556283 ! cell-substrate junction assembly GO:0007044 56 18 0,000 0,11843916 0,15547924 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,11843916 0,15539574 ! DNA integration GO:0015074 32 18 0,000 0,11843916 0,15531233 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,11843916 0,15522901 ! neural crest cell migration GO:0001755 41 18 0,000 0,11843916 0,15514577 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,11843916 0,15506263 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,11843916 0,15497958 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,11843916 0,15489661 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,11843916 0,15481373 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,11843916 0,15473095 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 0,000 0,11843916 0,15464825 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,11843916 0,15456563 ! detection of bacterium GO:0016045 22 18 0,000 0,11843916 0,15448311 ! nerve development GO:0021675 34 18 0,000 0,11843916 0,15440068 ! defense response to virus GO:0051607 43 18 0,000 0,11843916 0,15431833 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,11843916 0,15423607 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 0,000 0,11843916 0,1541539 ! regulation of cyclase activity GO:0031279 168 85 1,000 0,11899128 0,15479005 ! regulation of transmission of nerve impulse GO:0051969 167 85 1,000 0,11899128 0,15470767 ! cellular response to hormone stimulus GO:0032870 182 85 1,000 0,11899128 0,15462538 ! regulation of cAMP biosynthetic process GO:0030817 173 86 1,000 0,12128941 0,15752793 ! regulation of lyase activity GO:0051339 169 86 1,000 0,12128941 0,15744423 ! alcohol catabolic process GO:0046164 142 87 1,000 0,12359845 0,16035635 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,12459316 0,16156109 ! positive regulation of translation GO:0045727 31 19 0,000 0,12459316 0,16147538 ! negative regulation of defense response GO:0031348 27 19 0,000 0,12459316 0,16138976 ! G1 phase of mitotic cell cycle GO:0000080 39 19 0,000 0,12459316 0,16130424 ! neuron maturation GO:0042551 46 19 0,000 0,12459316 0,1612188 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,12459316 0,16113345 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 0,12459316 0,1610482 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,12459316 0,16096303 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,12459316 0,16087796 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,12459316 0,16079297 ! inositol metabolic process GO:0006020 33 19 0,000 0,12459316 0,16070808 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,12459316 0,16062327 ! memory GO:0007613 34 19 0,000 0,12459316 0,16053855 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,12459316 0,16045393 ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,12459316 0,16036939 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,12459316 0,16028494 ! pigmentation during development GO:0048066 42 19 0,000 0,12459316 0,16020058 ! response to vitamin A GO:0033189 32 19 0,000 0,12459316 0,16011631 ! heme metabolic process GO:0042168 40 19 0,000 0,12459316 0,16003212 ! neuromuscular junction development GO:0007528 43 19 0,000 0,12459316 0,15994803 ! response to fungus GO:0009620 26 19 0,000 0,12459316 0,15986402 ! peptide cross-linking GO:0018149 39 19 0,000 0,12459316 0,1597801 ! protein export from nucleus GO:0006611 40 19 0,000 0,12459316 0,15969627 ! heart process GO:0003015 32 19 0,000 0,12459316 0,15961253 GO:0060047|heart contraction, ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,12459316 0,15952888 ! cellular pigmentation GO:0033059 37 19 0,000 0,12459316 0,15944531 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,12459316 0,15936183 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,12459316 0,15927844 ! vitamin transport GO:0051180 31 19 0,000 0,12459316 0,15919513 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,12459316 0,15911192 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,12459316 0,15902879 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,12459316 0,15894574 ! cilium assembly GO:0042384 38 19 0,000 0,12459316 0,15886278 ! peptide hormone secretion GO:0030072 32 19 0,000 0,12459316 0,15877991 ! cellular respiration GO:0045333 143 88 1,000 0,12591813 0,16038477 ! one-carbon metabolic process GO:0006730 167 88 1,000 0,12591813 0,16030119 ! regulation of cAMP metabolic process GO:0030814 182 89 1,000 0,12824819 0,16318246 ! protein localization in nucleus GO:0034504 192 89 1,000 0,12824819 0,16309752 ! response to inorganic substance GO:0010035 173 90 1,000 0,13058838 0,16598721 ! protein secretion GO:0009306 45 20 0,000 0,13070438 0,16604825 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,13070438 0,16596195 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,13070438 0,16587574 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,13070438 0,16578961 ! skin development GO:0043588 42 20 0,000 0,13070438 0,16570358 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,13070438 0,16561763 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,13070438 0,16553177 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,13070438 0,16544601 ! response to vitamin GO:0033273 36 20 0,000 0,13070438 0,16536033 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,13070438 0,16527474 ! regulation of carbohydrate metabolic process GO:0006109 37 20 0,000 0,13070438 0,16518924 GO:0010675|regulation of cellular carbohydrate metabolic process, ! bile acid metabolic process GO:0008206 34 20 0,000 0,13070438 0,16510382 ! response to alkaloid GO:0043279 38 20 0,000 0,13070438 0,1650185 ! retinoid metabolic process GO:0001523 34 20 0,000 0,13070438 0,16493326 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 40 20 0,000 0,13070438 0,16484811 ! apoptotic mitochondrial changes GO:0008637 42 20 0,000 0,13070438 0,16476305 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,13070438 0,16467808 ! cellular response to unfolded protein GO:0034620 35 20 0,000 0,13070438 0,16459319 GO:0030968|endoplasmic reticulum unfolded protein response, ! actin filament bundle formation GO:0051017 47 20 0,000 0,13070438 0,16450839 ! body fluid secretion GO:0007589 33 20 0,000 0,13070438 0,16442368 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,13070438 0,16433906 ! peptide secretion GO:0002790 38 20 0,000 0,13070438 0,16425452 ! regulation of fatty acid metabolic process GO:0019217 45 20 0,000 0,13070438 0,16417007 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,13070438 0,16408571 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,13070438 0,16400143 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,13070438 0,16391724 ! cell-cell junction organization GO:0045216 43 20 0,000 0,13070438 0,16383314 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 0,000 0,13070438 0,16374912 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,13070438 0,16366519 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,13070438 0,16358135 ! regulation of glucose import GO:0046324 30 20 0,000 0,13070438 0,16349759 GO:0010827|regulation of glucose transport, ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,13070438 0,16341392 ! negative regulation of T cell activation GO:0050868 41 20 0,000 0,13070438 0,16333033 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,13070438 0,16324683 ! negative regulation of translation GO:0017148 32 20 0,000 0,13070438 0,16316341 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,13070438 0,16308008 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 1,000 0,13293844 0,16578286 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! regulation of cell killing GO:0031341 46 21 0,000 0,1367731 0,1704779 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,1367731 0,17039097 ! hormone secretion GO:0046879 39 21 0,000 0,1367731 0,17030412 ! cAMP metabolic process GO:0046058 41 21 0,000 0,1367731 0,17021736 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,1367731 0,17013069 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,1367731 0,17004411 ! ovarian follicle development GO:0001541 39 21 0,000 0,1367731 0,16995762 ! smooth muscle contraction GO:0006939 48 21 0,000 0,1367731 0,16987122 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,1367731 0,1697849 ! cell structure disassembly during apoptosis GO:0006921 32 21 0,000 0,1367731 0,16969867 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,1367731 0,16961253 ! plasma membrane fusion GO:0045026 33 21 0,000 0,1367731 0,16952648 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,1367731 0,16944051 GO:0006692|prostanoid metabolic process, ! regulation of vasoconstriction GO:0019229 40 21 0,000 0,1367731 0,16935463 ! sensory perception of pain GO:0019233 33 21 0,000 0,1367731 0,16926884 ! diencephalon development GO:0021536 36 21 0,000 0,1367731 0,16918313 ! positive regulation of inflammatory response GO:0050729 41 21 0,000 0,1367731 0,16909751 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,1367731 0,16901198 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 0,1367731 0,16892653 ! collagen catabolic process GO:0030574 29 21 0,000 0,1367731 0,16884117 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,1367731 0,1687559 GO:0043450|alkene biosynthetic process, ! sperm-egg recognition GO:0035036 23 21 0,000 0,1367731 0,16867071 ! actin filament-based movement GO:0030048 47 21 0,000 0,1367731 0,16858561 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 0,000 0,1367731 0,1685006 ! regulation of cell morphogenesis GO:0022604 243 93 1,000 0,13766719 0,16951661 ! positive regulation of MAP kinase activity GO:0043406 174 93 1,000 0,13766719 0,16943121 ! nitrogen compound catabolic process GO:0044270 167 94 1,000 0,14004539 0,17227135 ! regulation of membrane potential GO:0042391 179 94 1,000 0,14004539 0,17218465 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 1,000 0,14243248 0,17503146 ! cofactor biosynthetic process GO:0051188 161 95 1,000 0,14243248 0,17494346 ! negative regulation of multicellular organismal process GO:0051241 174 95 1,000 0,14243248 0,17485555 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,14279963 0,17521822 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,14279963 0,17513026 ! microtubule-based transport GO:0010970 59 22 0,000 0,14279963 0,17504239 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,14279963 0,17495461 ! inactivation of MAPK activity GO:0000188 45 22 0,000 0,14279963 0,17486691 ! cellular response to starvation GO:0009267 37 22 0,000 0,14279963 0,1747793 ! vacuolar transport GO:0007034 41 22 0,000 0,14279963 0,17469178 ! central nervous system neuron development GO:0021954 47 22 0,000 0,14279963 0,17460435 ! fucose metabolic process GO:0006004 44 22 0,000 0,14279963 0,174517 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,14279963 0,17442974 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,14279963 0,17434257 ! ureteric bud development GO:0001657 50 22 0,000 0,14279963 0,17425549 ! stem cell differentiation GO:0048863 57 22 0,000 0,14279963 0,17416849 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 0,14279963 0,17408158 ! cytolysis GO:0019835 27 22 0,000 0,14279963 0,17399476 ! renal system process GO:0003014 42 22 0,000 0,14279963 0,17390802 ! vasodilation GO:0042311 40 22 0,000 0,14279963 0,17382137 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,14279963 0,1737348 ! G1 phase GO:0051318 44 22 0,000 0,14279963 0,17364833 ! detection of chemical stimulus GO:0009593 42 22 0,000 0,14279963 0,17356193 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,14279963 0,17347563 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,14279963 0,17338941 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,14279963 0,17330327 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,14279963 0,17321722 ! sarcomere organization GO:0045214 32 22 0,000 0,14279963 0,17313126 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,14279963 0,17304538 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,14279963 0,17295959 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,14279963 0,17287388 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,14279963 0,17278825 ! gut development GO:0048565 44 22 0,000 0,14279963 0,17270272 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,14279963 0,17261726 ! transcription initiation GO:0006352 171 97 1,000 0,14723238 0,17788759 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,14878425 0,17967371 ! gluconeogenesis GO:0006094 38 23 0,000 0,14878425 0,17958494 ! glycerol metabolic process GO:0006071 40 23 0,000 0,14878425 0,17949625 ! viral genome replication GO:0019079 44 23 0,000 0,14878425 0,17940766 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,14878425 0,17931915 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,14878425 0,17923073 ! regeneration GO:0031099 42 23 0,000 0,14878425 0,17914239 ! axis specification GO:0009798 43 23 0,000 0,14878425 0,17905414 ! regulation of DNA recombination GO:0000018 51 23 0,000 0,14878425 0,17896598 ! response to ethanol GO:0045471 47 23 0,000 0,14878425 0,17887791 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,14878425 0,17878992 ! activation of pro-apoptotic gene products GO:0008633 51 23 0,000 0,14878425 0,17870202 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,14878425 0,17861421 ! peroxisome organization GO:0007031 43 23 0,000 0,14878425 0,17852648 ! lysosome organization GO:0007040 47 23 0,000 0,14878425 0,17843884 ! vesicle targeting GO:0006903 49 23 0,000 0,14878425 0,17835128 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,14878425 0,17826381 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,14878425 0,17817643 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,14878425 0,17808913 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,14878425 0,17800192 ! DNA modification GO:0006304 36 23 0,000 0,14878425 0,17791479 ! fatty acid transport GO:0015908 47 23 0,000 0,14878425 0,17782775 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,14878425 0,17774079 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,14878425 0,17765392 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,14878425 0,17756713 ! hormone transport GO:0009914 41 23 0,000 0,14878425 0,17748043 ! cell-cell recognition GO:0009988 28 23 0,000 0,14878425 0,17739381 ! regulation of nucleotide metabolic process GO:0006140 197 98 1,000 0,14964473 0,17833272 ! skeletal muscle tissue development GO:0007519 223 100 1,000 0,15449305 0,18402073 GO:0060538|skeletal muscle organ development, ! positive regulation of immune response GO:0050778 175 100 1,000 0,15449305 0,18393106 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,15472725 0,18412015 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 55 24 0,000 0,15472725 0,18403051 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 0,000 0,15472725 0,18394096 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,15472725 0,1838515 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,15472725 0,18376212 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,15472725 0,18367283 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,15472725 0,18358362 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,15472725 0,1834945 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,15472725 0,18340547 GO:0042278|purine nucleoside metabolic process, ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,15472725 0,18331653 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,15472725 0,18322767 GO:0051693|actin filament capping, ! sex determination GO:0007530 48 24 0,000 0,15472725 0,18313889 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,15472725 0,18305021 GO:0002708|positive regulation of lymphocyte mediated immunity, ! leukotriene metabolic process GO:0006691 47 24 0,000 0,15472725 0,18296161 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,15472725 0,18287309 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,15472725 0,18278466 ! membrane depolarization GO:0051899 45 24 0,000 0,15472725 0,18269632 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,15472725 0,18260806 ! platelet activation GO:0030168 41 24 0,000 0,15472725 0,18251988 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,15472725 0,18243179 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,15472725 0,18234379 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,15472725 0,18225587 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,15472725 0,18216804 ! regulation of amine transport GO:0051952 41 24 0,000 0,15472725 0,18208029 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 0,000 0,15472725 0,18199262 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,16062893 0,18884335 ! leukocyte adhesion GO:0007159 55 25 0,000 0,16062893 0,18875251 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,16062893 0,18866177 ! phototransduction GO:0007602 37 25 0,000 0,16062893 0,18857111 ! keratinization GO:0031424 37 25 0,000 0,16062893 0,18848054 ! vacuole organization GO:0007033 49 25 0,000 0,16062893 0,18839005 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,16062893 0,18829965 ! receptor metabolic process GO:0043112 53 25 0,000 0,16062893 0,18820934 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,16062893 0,18811912 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,16062893 0,18802898 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,16062893 0,18793893 ! immunoglobulin production GO:0002377 62 25 0,000 0,16062893 0,18784896 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,16062893 0,18775908 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,16062893 0,18766929 ! protein tetramerization GO:0051262 57 25 0,000 0,16062893 0,18757958 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,16648957 0,19433063 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,16648957 0,19423783 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,16648957 0,19414512 ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,16648957 0,19405249 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,16648957 0,19395995 GO:0006479|protein amino acid methylation, ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,16648957 0,1938675 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,16648957 0,19377514 ! digestive system process GO:0022600 49 26 0,000 0,16648957 0,19368287 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,16648957 0,19359068 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 0,000 0,16648957 0,19349858 ! regulation of cellular ketone metabolic process GO:0010565 51 26 0,000 0,16648957 0,19340657 ! neural crest cell development GO:0014032 59 26 0,000 0,16648957 0,19331465 GO:0014033|neural crest cell differentiation, ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,16648957 0,19322281 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,16648957 0,19313106 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,16648957 0,1930394 ! regulation of blood coagulation GO:0030193 46 26 0,000 0,16648957 0,19294783 ! regulation of osteoblast differentiation GO:0045667 68 26 0,000 0,16648957 0,19285634 ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,16648957 0,19276494 ! telomere organization GO:0032200 46 26 0,000 0,16648957 0,19267362 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,16648957 0,1925824 ! alditol metabolic process GO:0019400 44 26 0,000 0,16648957 0,19249125 ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,16648957 0,1924002 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,16648957 0,19230923 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,17230945 0,19893761 ! embryonic pattern specification GO:0009880 49 27 0,000 0,17230945 0,19884364 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,17230945 0,19874976 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,17230945 0,19865597 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,17230945 0,19856226 ! iron ion transport GO:0006826 65 27 0,000 0,17230945 0,19846864 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,17230945 0,19837511 ! superoxide metabolic process GO:0006801 41 27 0,000 0,17230945 0,19828167 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,17230945 0,19818832 ! mitochondrial membrane organization GO:0007006 60 27 0,000 0,17230945 0,19809505 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,17230945 0,19800188 ! response to starvation GO:0042594 47 27 0,000 0,17230945 0,19790879 ! response to toxin GO:0009636 49 27 0,000 0,17230945 0,19781579 ! cellular response to nutrient levels GO:0031669 45 27 0,000 0,17230945 0,19772287 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,17230945 0,19763004 ! leukocyte proliferation GO:0070661 59 27 0,000 0,17230945 0,1975373 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 55 27 0,000 0,17230945 0,19744465 ! neuron fate commitment GO:0048663 52 28 0,000 0,17808886 0,20397144 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,17808886 0,20387586 ! vesicle docking GO:0048278 55 28 0,000 0,17808886 0,20378037 ! dendrite development GO:0016358 67 28 0,000 0,17808886 0,20368497 ! fat cell differentiation GO:0045444 57 28 0,000 0,17808886 0,20358965 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,17808886 0,20349443 ! sperm motility GO:0030317 37 28 0,000 0,17808886 0,20339929 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,17808886 0,20330425 ! base-excision repair GO:0006284 41 28 0,000 0,17808886 0,20320929 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,17808886 0,20311442 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,17808886 0,20301964 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,17808886 0,20292495 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,17808886 0,20283034 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,17808886 0,20273583 ! peptidyl-tyrosine modification GO:0018212 57 28 0,000 0,17808886 0,2026414 ! glutathione metabolic process GO:0006749 42 28 0,000 0,17808886 0,20254706 ! lipid oxidation GO:0034440 48 28 0,000 0,17808886 0,20245281 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,17808886 0,20235865 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,17808886 0,20226457 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 0,000 0,18382808 0,20868587 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,18382808 0,20858894 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! autophagy GO:0006914 47 29 0,000 0,18382808 0,2084921 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,18382808 0,20839535 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,18382808 0,2082987 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,18382808 0,20820213 ! negative regulation of neuron differentiation GO:0045665 46 29 0,000 0,18382808 0,20810565 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,18382808 0,20800926 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,18382808 0,20791296 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,18952738 0,21425978 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,18952738 0,21416067 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,18952738 0,21406166 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,18952738 0,21396274 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,18952738 0,21386392 ! acute-phase response GO:0006953 50 30 0,000 0,18952738 0,21376518 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,18952738 0,21366653 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,18952738 0,21356798 ! myofibril assembly GO:0030239 50 30 0,000 0,18952738 0,21346952 GO:0055002|striated muscle cell development, ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,18952738 0,21337114 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,18952738 0,21327286 ! cell fate determination GO:0001709 64 30 0,000 0,18952738 0,21317467 ! positive regulation of multicellular organism growth GO:0040018 55 30 0,000 0,18952738 0,21307657 ! phospholipid transport GO:0015914 65 30 0,000 0,18952738 0,21297856 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,18952738 0,21288063 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,18952738 0,2127828 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,18952738 0,21268506 ! regulation of coagulation GO:0050818 52 30 0,000 0,18952738 0,21258741 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,19518704 0,21883521 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,19518704 0,21873483 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,19518704 0,21863454 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,19518704 0,21853434 ! cell junction assembly GO:0034329 85 31 0,000 0,19518704 0,21843423 ! regulation of innate immune response GO:0045088 57 31 0,000 0,19518704 0,21833422 ! ovulation cycle process GO:0022602 55 31 0,000 0,19518704 0,21823429 ! peptide transport GO:0015833 60 31 0,000 0,19518704 0,21813446 ! male gonad development GO:0008584 56 31 0,000 0,19518704 0,21803472 ! detection of light stimulus GO:0009583 44 31 0,000 0,19518704 0,21793507 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 0,000 0,19518704 0,21783551 ! negative regulation of leukocyte activation GO:0002695 60 31 0,000 0,19518704 0,21773604 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,19518704 0,21763666 ! response to heat GO:0009408 54 31 0,000 0,19518704 0,21753738 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,19518704 0,21743818 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,20080733 0,22359723 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,20080733 0,22349536 ! collagen metabolic process GO:0032963 49 32 0,000 0,20080733 0,22339359 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,20080733 0,22329191 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,20080733 0,22319032 ! muscle cell development GO:0055001 52 32 0,000 0,20080733 0,22308882 ! mesoderm formation GO:0001707 73 32 0,000 0,20080733 0,22298742 ! hexose biosynthetic process GO:0019319 53 32 0,000 0,20080733 0,22288611 ! ovulation cycle GO:0042698 57 32 0,000 0,20080733 0,22278489 ! BMP signaling pathway GO:0030509 71 32 0,000 0,20080733 0,22268376 ! gene silencing GO:0016458 71 32 0,000 0,20080733 0,22258272 ! regulation of pH GO:0006885 56 33 0,000 0,20638854 0,2286654 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,20638854 0,22856174 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,20638854 0,22845818 GO:0055092|sterol homeostasis, ! pigment biosynthetic process GO:0046148 73 33 0,000 0,20638854 0,22835471 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,20638854 0,22825134 ! triglyceride metabolic process GO:0006641 46 33 0,000 0,20638854 0,22814806 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,20638854 0,22804487 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,20638854 0,22794177 ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,20638854 0,22783877 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,20638854 0,22773586 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,20638854 0,22763305 ! post-embryonic development GO:0009791 76 34 0,000 0,21193093 0,23364046 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,21193093 0,23353507 ! cholesterol transport GO:0030301 62 34 0,000 0,21193093 0,23342978 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,21193093 0,23332458 ! spliceosome assembly GO:0000245 75 34 0,000 0,21193093 0,23321948 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,21193093 0,23311448 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,21193093 0,23300956 ! formation of primary germ layer GO:0001704 76 34 0,000 0,21193093 0,23290475 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,21193093 0,23280002 ! DNA damage checkpoint GO:0000077 78 35 0,000 0,21743476 0,23873848 ! negative regulation of secretion GO:0051048 68 35 0,000 0,21743476 0,23863123 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,21743476 0,23852408 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,21743476 0,23841702 ! membrane docking GO:0022406 69 35 0,000 0,21743476 0,23831006 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,21743476 0,23820319 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,21743476 0,23809642 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,21743476 0,23798975 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,21743476 0,23788317 ! ceramide metabolic process GO:0006672 72 35 0,000 0,21743476 0,23777669 ! sterol transport GO:0015918 63 35 0,000 0,21743476 0,2376703 ! vesicle localization GO:0051648 70 35 0,000 0,21743476 0,23756401 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,22290031 0,24342667 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,22290031 0,2433179 ! protein targeting to membrane GO:0006612 75 36 0,000 0,22290031 0,24320922 ! regulation of proteolysis GO:0030162 77 36 0,000 0,22290031 0,24310065 ! cytokine production GO:0001816 68 36 0,000 0,22290031 0,24299217 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,22290031 0,24288379 ! monosaccharide biosynthetic process GO:0046364 57 36 0,000 0,22290031 0,2427755 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 0,000 0,22832784 0,24857616 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! regulation of smooth muscle cell proliferation GO:0048660 64 37 0,000 0,22832784 0,24846544 ! negative regulation of cell adhesion GO:0007162 94 37 0,000 0,22832784 0,24835481 ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,22832784 0,24824428 ! odontogenesis GO:0042476 74 37 0,000 0,22832784 0,24813386 ! actomyosin structure organization GO:0031032 68 37 0,000 0,22832784 0,24802352 ! cell junction organization GO:0034330 96 37 0,000 0,22832784 0,24791329 ! maintenance of protein location in cell GO:0032507 89 37 0,000 0,22832784 0,24780316 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,22832784 0,24769312 ! regulation of microtubule-based process GO:0032886 86 37 0,000 0,22832784 0,24758318 ! negative regulation of cell activation GO:0050866 69 37 0,000 0,22832784 0,24747334 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,23371761 0,25320272 ! organic anion transport GO:0015711 82 38 0,000 0,23371761 0,25309048 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,23371761 0,25297835 ! neutral lipid metabolic process GO:0006638 54 38 0,000 0,23371761 0,25286631 GO:0006639|acylglycerol metabolic process, ! DNA integrity checkpoint GO:0031570 82 38 0,000 0,23371761 0,25275437 ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,23371761 0,25264253 ! spermatid development GO:0007286 69 38 0,000 0,23371761 0,25253079 ! pigment metabolic process GO:0042440 87 38 0,000 0,23371761 0,25241915 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,23906989 0,25808561 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,23906989 0,25797162 ! carbohydrate homeostasis GO:0033500 59 39 0,000 0,23906989 0,25785772 GO:0042593|glucose homeostasis, ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,23906989 0,25774393 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,23906989 0,25763024 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,23906989 0,25751664 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,24438494 0,26312578 GO:0006956|complement activation, ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,24438494 0,26300987 ! lipid homeostasis GO:0055088 75 40 0,000 0,24438494 0,26289405 ! mismatch repair GO:0006298 58 40 0,000 0,24438494 0,26277834 ! glycerol ether metabolic process GO:0006662 57 40 0,000 0,24438494 0,26266274 ! mRNA catabolic process GO:0006402 79 41 0,000 0,249663 0,26821755 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,249663 0,26809966 ! regulation of hormone secretion GO:0046883 69 41 0,000 0,249663 0,26798186 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,249663 0,26786417 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,249663 0,26774658 ! monovalent inorganic cation homeostasis GO:0055067 72 41 0,000 0,249663 0,2676291 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,249663 0,26751172 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 95 41 0,000 0,249663 0,26739444 ! spermatid differentiation GO:0048515 73 41 0,000 0,249663 0,26727726 ! RNA modification GO:0009451 64 41 0,000 0,249663 0,26716019 ! ear morphogenesis GO:0042471 64 42 0,000 0,25490435 0,27264944 ! organic ether metabolic process GO:0018904 59 42 0,000 0,25490435 0,27253012 ! alcohol biosynthetic process GO:0046165 65 42 0,000 0,25490435 0,27241091 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,25490435 0,27229179 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,25490435 0,27217278 ! regulation of protein secretion GO:0050708 77 42 0,000 0,25490435 0,27205388 ! dorsal/ventral pattern formation GO:0009953 75 42 0,000 0,25490435 0,27193508 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,25490435 0,27181638 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,26010923 0,27724558 ! regulation of tube size GO:0035150 76 43 0,000 0,26010923 0,27712467 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,26010923 0,27700386 ! glucose transport GO:0015758 66 43 0,000 0,26010923 0,27688316 ! striated muscle cell differentiation GO:0051146 91 43 0,000 0,26010923 0,27676257 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,26010923 0,27664208 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,26010923 0,2765217 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,26010923 0,27640142 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,26010923 0,27628124 ! ion transmembrane transport GO:0034220 79 43 0,000 0,26010923 0,27616117 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,2652779 0,28152646 ! negative regulation of protein complex disassembly GO:0043242 113 44 0,000 0,2652779 0,28140422 ! hexose transport GO:0008645 68 44 0,000 0,2652779 0,28128208 GO:0015749|monosaccharide transport, ! striated muscle contraction GO:0006941 85 44 0,000 0,2652779 0,28116005 ! phagocytosis GO:0006909 105 44 0,000 0,2652779 0,28103812 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,27041061 0,28635159 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! keratinocyte differentiation GO:0030216 81 45 0,000 0,27041061 0,28622752 ! biopolymer methylation GO:0043414 91 45 0,000 0,27041061 0,28610356 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,27041061 0,2859797 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,27041061 0,28585596 ! polyol metabolic process GO:0019751 77 45 0,000 0,27041061 0,28573232 ! maintenance of location in cell GO:0051651 101 45 0,000 0,27041061 0,28560878 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,2755076 0,2908665 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,2755076 0,29074085 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,2755076 0,29061532 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,28056913 0,29582667 ! positive regulation of defense response GO:0031349 88 48 0,000 0,28559544 0,3009964 ! mitochondrial transport GO:0006839 94 48 0,000 0,28559544 0,3008666 ! cellular component disassembly GO:0022411 89 48 0,000 0,28559544 0,30073692 ! vascular process in circulatory system GO:0003018 85 48 0,000 0,28559544 0,30060735 ! male sex differentiation GO:0046661 93 48 0,000 0,28559544 0,30047789 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,28559544 0,30034854 ! regulation of inflammatory response GO:0050727 84 48 0,000 0,28559544 0,3002193 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,28559544 0,30009017 ! methylation GO:0032259 97 48 0,000 0,28559544 0,29996116 ! detection of stimulus involved in sensory perception GO:0050906 75 49 0,000 0,29058677 0,3050724 ! regulation of ion transport GO:0043269 86 50 0,000 0,29554337 0,31014281 ! induction of apoptosis by extracellular signals GO:0008624 99 50 0,000 0,29554337 0,31000964 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,29554337 0,30987659 ! activation of caspase activity GO:0006919 95 50 0,000 0,29554337 0,30974365 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,29554337 0,30961083 GO:0019724|B cell mediated immunity, ! regulation of gene expression, epigenetic GO:0040029 116 50 0,000 0,29554337 0,30947812 ! epidermal cell differentiation GO:0009913 87 50 0,000 0,29554337 0,30934552 ! peptide metabolic process GO:0006518 80 51 0,000 0,30046548 0,31436281 ! response to temperature stimulus GO:0009266 84 51 0,000 0,30046548 0,31422824 ! detection of abiotic stimulus GO:0009582 80 51 0,000 0,30046548 0,31409378 ! regulation of protein complex disassembly GO:0043244 127 52 0,000 0,30535333 0,3190668 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,30535333 0,31893039 ! excretion GO:0007588 87 52 0,000 0,30535333 0,3187941 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,30535333 0,31865792 ! amino acid activation GO:0043038 98 52 0,000 0,30535333 0,31852185 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,31020717 0,32344691 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,31020717 0,32330892 ! regulation of translational initiation GO:0006446 87 54 0,000 0,31502722 0,32819254 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,31502722 0,32805264 ! regulation of muscle contraction GO:0006937 94 54 0,000 0,31502722 0,32791287 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,31502722 0,32777321 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,31502722 0,32763368 ! regulation of cell shape GO:0008360 142 54 0,000 0,31502722 0,32749426 ! RNA catabolic process GO:0006401 103 55 0,000 0,31981373 0,33232877 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,31981373 0,33218748 ! cell recognition GO:0008037 98 55 0,000 0,31981373 0,3320463 ! regulation of multicellular organism growth GO:0040014 90 55 0,000 0,31981373 0,33190525 ! skeletal muscle fiber development GO:0048741 130 56 0,000 0,32456693 0,33669512 ! negative regulation of cytoskeleton organization GO:0051494 139 56 0,000 0,32456693 0,33655221 ! chloride transport GO:0006821 102 57 0,000 0,32928704 0,34130176 ! positive regulation of caspase activity GO:0043280 108 57 0,000 0,32928704 0,34115702 GO:0010952|positive regulation of peptidase activity, ! muscle fiber development GO:0048747 131 57 0,000 0,32928704 0,3410124 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,3339743 0,34572001 ! gastrulation GO:0007369 122 58 0,000 0,3339743 0,34557358 ! maintenance of location GO:0051235 124 58 0,000 0,3339743 0,34542727 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,34325117 0,35487203 ! regulation of endocytosis GO:0030100 104 60 0,000 0,34325117 0,35472192 ! positive regulation of secretion GO:0051047 110 61 0,000 0,34784123 0,35931338 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,34784123 0,35916151 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,34784123 0,35900977 ! cytokine-mediated signaling pathway GO:0019221 112 61 0,000 0,34784123 0,35885817 ! proton transport GO:0015992 117 61 0,000 0,34784123 0,35870668 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,35239934 0,36325384 ! tRNA processing GO:0008033 102 62 0,000 0,35239934 0,36310063 ! mesoderm development GO:0007498 128 63 0,000 0,35692572 0,36760942 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,35692572 0,3674545 ! hydrogen transport GO:0006818 121 64 0,000 0,36142059 0,37192523 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,36142059 0,37176863 ! integrin-mediated signaling pathway GO:0007229 160 64 0,000 0,36142059 0,37161216 ! lymphocyte mediated immunity GO:0002449 122 65 0,000 0,36588417 0,37604334 ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,36588417 0,37588521 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,36588417 0,3757272 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,37031667 0,38011917 ! activation of MAPK activity GO:0000187 124 67 0,000 0,37471831 0,38447578 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,37471831 0,38431437 ! secondary metabolic process GO:0019748 125 67 0,000 0,37471831 0,3841531 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,37908931 0,38847113 ! detection of external stimulus GO:0009581 102 68 0,000 0,37908931 0,38830825 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,38342987 0,39258976 ! cell redox homeostasis GO:0045454 114 70 0,000 0,38774021 0,39683676 ! activation of immune response GO:0002253 120 70 0,000 0,38774021 0,39667058 ! protein maturation by peptide bond cleavage GO:0051605 118 70 0,000 0,38774021 0,39650454 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,39202054 0,40071389 ! cAMP-mediated signaling GO:0019933 124 71 0,000 0,39202054 0,40054629 ! carbohydrate transport GO:0008643 114 72 0,000 0,39627107 0,40471999 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,39627107 0,40455087 ! humoral immune response GO:0006959 115 73 0,000 0,400492 0,4086892 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,400492 0,40851856 ! regulation of immune effector process GO:0002697 156 73 0,000 0,400492 0,40834806 ! acute inflammatory response GO:0002526 118 74 0,000 0,40468353 0,41244968 ! amino acid transport GO:0006865 148 74 0,000 0,40468353 0,41227768 ! regulation of caspase activity GO:0043281 136 74 0,000 0,40468353 0,41210582 ! transition metal ion transport GO:0000041 143 75 0,000 0,40884588 0,41617104 ! axon guidance GO:0007411 162 75 0,000 0,40884588 0,41599771 ! cell-matrix adhesion GO:0007160 181 76 0,000 0,41297924 0,42002843 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,41297924 0,41985364 ! regulation of blood pressure GO:0008217 134 76 0,000 0,41297924 0,41967899 ! neurotransmitter transport GO:0006836 142 77 0,000 0,41708382 0,42367392 ! regulation of endopeptidase activity GO:0052548 141 77 0,000 0,41708382 0,42349783 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,41708382 0,42332188 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,41708382 0,42314609 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,42115981 0,42710395 ! antigen processing and presentation GO:0019882 117 78 0,000 0,42115981 0,42692673 ! blood coagulation GO:0007596 151 79 0,000 0,42520742 0,43085098 GO:0050817|coagulation, ! steroid biosynthetic process GO:0006694 146 79 0,000 0,42520742 0,43067236 ! muscle cell differentiation GO:0042692 178 81 0,000 0,43321825 0,43860431 ! regulation of peptidase activity GO:0052547 150 82 0,000 0,43718188 0,44243385 ! cell-substrate adhesion GO:0031589 189 82 0,000 0,43718188 0,44225065 ! exocytosis GO:0006887 153 83 0,000 0,44111789 0,4460476 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,44111789 0,44586305 ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,44111789 0,44567866 ! inorganic anion transport GO:0015698 156 83 0,000 0,44111789 0,44549442 ! digestion GO:0007586 130 84 0,000 0,44502649 0,44925608 ! hemostasis GO:0007599 165 85 0,000 0,44890786 0,45298715 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,44890786 0,45280012 ! regulation of neuron differentiation GO:0045664 187 85 0,000 0,44890786 0,45261325 ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,45658968 0,46016856 ! mitochondrion organization GO:0007005 159 87 0,000 0,45658968 0,4599788 ! nucleosome assembly GO:0006334 126 87 0,000 0,45658968 0,45978919 ! sensory perception of smell GO:0007608 117 88 0,000 0,4603905 0,46342562 ! chromatin assembly GO:0031497 128 88 0,000 0,4603905 0,46323476 ! cellular defense response GO:0006968 123 89 0,000 0,46416484 0,46684015 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,46791289 0,47041613 ! response to unfolded protein GO:0006986 139 90 0,000 0,46791289 0,47022262 ! defense response to bacterium GO:0042742 112 91 0,000 0,47163483 0,47376805 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,47533084 0,47728452 ! amine transport GO:0015837 181 93 0,000 0,4790011 0,48077226 ! vitamin metabolic process GO:0006766 153 93 0,000 0,4790011 0,48057482 ! sterol metabolic process GO:0016125 166 94 0,000 0,48264578 0,4840327 ! carbohydrate biosynthetic process GO:0016051 158 94 0,000 0,48264578 0,48383408 ! regulation of defense response GO:0031347 171 95 0,000 0,48626507 0,48726233 ! nucleosome organization GO:0034728 143 95 0,000 0,48626507 0,48706256 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,48626507 0,48686294 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,48626507 0,48666349 ! response to protein stimulus GO:0051789 158 96 0,000 0,48985914 0,49005974 ! hormone metabolic process GO:0042445 171 100 0,000 0,50398673 0,50398673