pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6657-VanDeVijver-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/vantveer-oligo_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! protein amino acid autophosphorylation GO:0046777 28 28 3,000 3,612E-06 6,658E-03 ! platelet-derived growth factor receptor signaling pathway GO:0048008 9 9 2,000 4,458E-06 4,108E-03 ! regulation of cell migration GO:0030334 71 71 4,000 6,868E-06 4,22E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 11 11 2,000 8,711E-06 4,014E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 35 35 3,000 9,066E-06 3,342E-03 ! positive regulation of cell migration GO:0030335 36 36 3,000 1,017E-05 3,125E-03 ! regulation of locomotion GO:0040012 79 79 4,000 1,164E-05 3,064E-03 ! regulation of cell motion GO:0051270 79 79 4,000 1,164E-05 2,681E-03 ! protein oligomerization GO:0051259 39 39 3,000 1,409E-05 2,885E-03 ! positive regulation of cell motion GO:0051272 39 39 3,000 1,409E-05 2,597E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 13 13 2,000 1,502E-05 2,517E-03 ! protein tetramerization GO:0051262 13 13 2,000 1,502E-05 2,307E-03 ! positive regulation of protein kinase activity GO:0045860 89 86 4,000 1,765E-05 2,502E-03 ! heart development GO:0007507 90 87 4,000 1,867E-05 2,458E-03 ! positive regulation of epithelial cell proliferation GO:0050679 14 14 2,000 1,907E-05 2,343E-03 ! positive regulation of transferase activity GO:0051347 91 88 4,000 1,975E-05 2,275E-03 GO:0033674|positive regulation of kinase activity, ! positive regulation of MAP kinase activity GO:0043406 50 49 3,000 3,534E-05 3,831E-03 ! ensheathment of neurons GO:0007272 18 18 2,000 4,23E-05 4,331E-03 GO:0008366|axon ensheathment, ! regulation of action potential in neuron GO:0019228 21 21 2,000 6,84E-05 6,635E-03 ! angiogenesis GO:0001525 65 64 3,000 1,018E-04 9,38E-03 ! regulation of action potential GO:0001508 24 24 2,000 1,033E-04 9,064E-03 ! regulation of MAP kinase activity GO:0043405 67 66 3,000 1,148E-04 9,621E-03 ! regulation of gene-specific transcription GO:0032583 25 25 2,000 1,171E-04 9,38E-03 ! striated muscle tissue development GO:0014706 69 67 3,000 1,218E-04 9,354E-03 ! muscle tissue development GO:0060537 72 70 3,000 1,445E-04 0,01065603 ! positive regulation of glucose metabolic process GO:0010907 5 5 1,000 1,473E-04 0,01043795 ! mRNA stabilization GO:0048255 5 5 1,000 1,473E-04 0,01005135 GO:0043489|RNA stabilization, ! regulation of phospholipase A2 activity GO:0032429 5 5 1,000 1,473E-04 9,692E-03 ! actin cytoskeleton reorganization GO:0031532 5 5 1,000 1,473E-04 9,358E-03 ! protein heterooligomerization GO:0051291 5 5 1,000 1,473E-04 9,046E-03 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 5 5 1,000 1,473E-04 8,754E-03 ! negative regulation of focal adhesion formation GO:0051895 6 5 1,000 1,473E-04 8,481E-03 ! decidualization GO:0046697 5 5 1,000 1,473E-04 8,224E-03 ! hair follicle maturation GO:0048820 5 5 1,000 1,473E-04 7,982E-03 ! T cell lineage commitment GO:0002360 5 5 1,000 1,473E-04 7,754E-03 ! peptidyl-lysine modification GO:0018205 5 5 1,000 1,473E-04 7,539E-03 ! negative regulation of neuroblast proliferation GO:0007406 5 5 1,000 1,473E-04 7,335E-03 ! positive regulation of blood vessel endothelial cell migration GO:0043536 5 5 1,000 1,473E-04 7,142E-03 ! regulation of epithelial cell proliferation GO:0050678 29 29 2,000 1,84E-04 8,697E-03 ! response to UV GO:0009411 29 29 2,000 1,84E-04 8,479E-03 ! N-terminal protein amino acid modification GO:0031365 6 6 1,000 2,203E-04 9,905E-03 GO:0018409|peptide or protein amino-terminal blocking, ! virus-host interaction GO:0019048 6 6 1,000 2,203E-04 9,669E-03 ! regulation of positive chemotaxis GO:0050926 6 6 1,000 2,203E-04 9,444E-03 GO:0050927|positive regulation of positive chemotaxis, ! positive regulation of transcription factor import into nucleus GO:0042993 6 6 1,000 2,203E-04 9,229E-03 ! ER overload response GO:0006983 6 6 1,000 2,203E-04 9,024E-03 ! negative regulation of T cell proliferation GO:0042130 6 6 1,000 2,203E-04 8,828E-03 GO:0070667|negative regulation of mast cell proliferation, ! regulation of vascular permeability GO:0043114 6 6 1,000 2,203E-04 8,64E-03 ! regulation of bone resorption GO:0045124 6 6 1,000 2,203E-04 8,46E-03 ! G1 DNA damage checkpoint GO:0031571 6 6 1,000 2,203E-04 8,288E-03 ! regulation of T cell differentiation in the thymus GO:0033081 6 6 1,000 2,203E-04 8,122E-03 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 6 6 1,000 2,203E-04 7,963E-03 ! phosphoinositide 3-kinase cascade GO:0014065 6 6 1,000 2,203E-04 7,81E-03 ! regulation of focal adhesion formation GO:0051893 7 6 1,000 2,203E-04 7,662E-03 ! regulation of cellular carbohydrate catabolic process GO:0043471 6 6 1,000 2,203E-04 7,52E-03 GO:0043470|regulation of carbohydrate catabolic process, GO:0006110|regulation of glycolysis, ! maternal placenta development GO:0001893 6 6 1,000 2,203E-04 7,384E-03 ! regulation of embryonic development GO:0045995 6 6 1,000 2,203E-04 7,252E-03 ! localization within membrane GO:0051668 6 6 1,000 2,203E-04 7,124E-03 ! regulation of DNA replication GO:0006275 32 31 2,000 2,252E-04 7,156E-03 ! lipid modification GO:0030258 32 32 2,000 2,479E-04 7,742E-03 ! blood vessel morphogenesis GO:0048514 84 83 3,000 2,798E-04 8,594E-03 ! positive regulation of cellular catabolic process GO:0031331 7 7 1,000 3,077E-04 9,298E-03 ! keratinocyte proliferation GO:0043616 7 7 1,000 3,077E-04 9,148E-03 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 7 7 1,000 3,077E-04 9,002E-03 ! negative regulation of lymphocyte proliferation GO:0050672 7 7 1,000 3,077E-04 8,862E-03 GO:0032945|negative regulation of mononuclear cell proliferation, GO:0070664|negative regulation of leukocyte proliferation, ! cardiac muscle tissue development GO:0048738 7 7 1,000 3,077E-04 8,725E-03 ! response to X-ray GO:0010165 7 7 1,000 3,077E-04 8,593E-03 ! regulation of intracellular pH GO:0051453 7 7 1,000 3,077E-04 8,465E-03 ! positive regulation of carbohydrate metabolic process GO:0045913 7 7 1,000 3,077E-04 8,341E-03 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! response to gamma radiation GO:0010332 8 7 1,000 3,077E-04 8,22E-03 ! negative regulation of cell-substrate adhesion GO:0010812 8 7 1,000 3,077E-04 8,102E-03 GO:0001953|negative regulation of cell-matrix adhesion, ! regulation of mRNA stability GO:0043488 7 7 1,000 3,077E-04 7,988E-03 ! negative regulation of T cell activation GO:0050868 7 7 1,000 3,077E-04 7,877E-03 ! negative regulation of protein kinase activity GO:0006469 37 37 2,000 3,832E-04 9,675E-03 ! lung development GO:0030324 38 37 2,000 3,832E-04 9,545E-03 ! negative regulation of cell cycle GO:0045786 92 91 3,000 3,983E-04 9,787E-03 ! sex determination GO:0007530 8 8 1,000 4,093E-04 9,926E-03 ! positive regulation of leukocyte migration GO:0002687 8 8 1,000 4,093E-04 9,797E-03 ! regulation of RNA stability GO:0043487 8 8 1,000 4,093E-04 9,671E-03 ! regulation of generation of precursor metabolites and energy GO:0043467 8 8 1,000 4,093E-04 9,549E-03 ! release of cytochrome c from mitochondria GO:0001836 9 8 1,000 4,093E-04 9,43E-03 ! negative regulation of bone remodeling GO:0046851 8 8 1,000 4,093E-04 9,313E-03 ! positive regulation of endothelial cell migration GO:0010595 8 8 1,000 4,093E-04 9,2E-03 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 8 8 1,000 4,093E-04 9,089E-03 ! negative regulation of kinase activity GO:0033673 38 38 2,000 4,15E-04 9,105E-03 ! respiratory tube development GO:0030323 40 39 2,000 4,484E-04 9,722E-03 ! respiratory system development GO:0060541 40 39 2,000 4,484E-04 9,609E-03 ! blood vessel development GO:0001568 95 94 3,000 4,508E-04 9,55E-03 ! negative regulation of transferase activity GO:0051348 40 40 2,000 4,835E-04 0,01012588 ! vasculature development GO:0001944 97 96 3,000 4,884E-04 0,01011466 ! regulation of caspase activity GO:0043281 41 41 2,000 5,203E-04 0,01065461 ! positive regulation of cell projection organization GO:0031346 9 9 1,000 5,25E-04 0,01063258 ! regulation of nitric-oxide synthase activity GO:0050999 9 9 1,000 5,25E-04 0,01051701 ! positive regulation of endothelial cell proliferation GO:0001938 9 9 1,000 5,25E-04 0,01040392 ! substrate-bound cell migration GO:0006929 9 9 1,000 5,25E-04 0,01029324 ! positive regulation of protein import into nucleus GO:0042307 9 9 1,000 5,25E-04 0,01018489 ! regulation of cellular pH GO:0030641 9 9 1,000 5,25E-04 0,0100788 ! histone acetylation GO:0016573 9 9 1,000 5,25E-04 9,975E-03 ! negative regulation of tissue remodeling GO:0034104 9 9 1,000 5,25E-04 9,873E-03 ! regulation of leukocyte migration GO:0002685 9 9 1,000 5,25E-04 9,773E-03 ! regulation of blood vessel endothelial cell migration GO:0043535 9 9 1,000 5,25E-04 9,676E-03 ! regulation of endopeptidase activity GO:0052548 42 42 2,000 5,589E-04 0,01019783 ! muscle organ development GO:0007517 102 100 3,000 5,704E-04 0,01030651 ! regulation of glucose metabolic process GO:0010906 10 10 1,000 6,547E-04 0,01171387 ! inositol metabolic process GO:0006020 10 10 1,000 6,547E-04 0,01160124 ! apoptotic mitochondrial changes GO:0008637 11 10 1,000 6,547E-04 0,01149075 ! centrosome cycle GO:0007098 10 10 1,000 6,547E-04 0,01138235 ! neuromuscular junction development GO:0007528 10 10 1,000 6,547E-04 0,01127597 ! embryo implantation GO:0007566 11 10 1,000 6,547E-04 0,01117156 ! epithelial to mesenchymal transition GO:0001837 10 10 1,000 6,547E-04 0,01106907 ! positive regulation of neuron apoptosis GO:0043525 10 10 1,000 6,547E-04 0,01096845 ! negative regulation of homeostatic process GO:0032845 10 10 1,000 6,547E-04 0,01086963 ! regulation of peptidase activity GO:0052547 46 46 2,000 7,313E-04 0,01203371 ! regulation of membrane potential GO:0042391 46 46 2,000 7,313E-04 0,01192722 ! endothelial cell migration GO:0043542 11 11 1,000 7,982E-04 0,0129042 ! protein amino acid acetylation GO:0006473 11 11 1,000 7,982E-04 0,01279199 ! positive regulation of nucleocytoplasmic transport GO:0046824 11 11 1,000 7,982E-04 0,01268171 GO:0032388|positive regulation of intracellular transport, ! activation of MAPKK activity GO:0000186 12 11 1,000 7,982E-04 0,01257332 ! cellular response to starvation GO:0009267 11 11 1,000 7,982E-04 0,01246677 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 11 11 1,000 7,982E-04 0,01236201 ! G1/S transition checkpoint GO:0031575 12 11 1,000 7,982E-04 0,01225899 ! interaction with host GO:0051701 11 11 1,000 7,982E-04 0,01215768 ! regulation of monooxygenase activity GO:0032768 11 11 1,000 7,982E-04 0,01205802 ! regulation of cellular carbohydrate metabolic process GO:0010675 11 11 1,000 7,982E-04 0,01195999 GO:0006109|regulation of carbohydrate metabolic process, ! vitamin A metabolic process GO:0006776 11 11 1,000 7,982E-04 0,01186354 ! negative regulation of lymphocyte activation GO:0051250 11 11 1,000 7,982E-04 0,01176863 ! cell cycle arrest GO:0007050 49 49 2,000 8,806E-04 0,01288113 ! skeletal muscle tissue development GO:0007519 50 49 2,000 8,806E-04 0,01277971 GO:0060538|skeletal muscle organ development, ! regulation of DNA metabolic process GO:0051052 51 50 2,000 9,344E-04 0,01345401 ! regulation of neurogenesis GO:0050767 51 50 2,000 9,344E-04 0,01334972 ! microtubule organizing center organization GO:0031023 12 12 1,000 9,555E-04 0,01354634 GO:0051297|centrosome organization, ! somitogenesis GO:0001756 13 12 1,000 9,555E-04 0,01344293 ! fat-soluble vitamin metabolic process GO:0006775 12 12 1,000 9,555E-04 0,01334109 ! cellular monovalent inorganic cation homeostasis GO:0030004 12 12 1,000 9,555E-04 0,01324079 ! interphase of mitotic cell cycle GO:0051329 52 51 2,000 9,902E-04 0,01361918 GO:0051325|interphase, ! response to light stimulus GO:0009416 53 52 2,000 1,048E-03 0,01430852 ! response to hypoxia GO:0001666 53 53 2,000 1,108E-03 0,01501622 ! positive regulation of DNA replication GO:0045740 14 13 1,000 1,127E-03 0,01515458 ! positive regulation of smooth muscle cell proliferation GO:0048661 13 13 1,000 1,127E-03 0,01504476 ! G2/M transition of mitotic cell cycle GO:0000086 13 13 1,000 1,127E-03 0,01493653 ! vasculogenesis GO:0001570 13 13 1,000 1,127E-03 0,01482984 ! mitochondrial membrane organization GO:0007006 13 13 1,000 1,127E-03 0,01472466 ! negative regulation of DNA replication GO:0008156 13 13 1,000 1,127E-03 0,01462097 ! cell aging GO:0007569 13 13 1,000 1,127E-03 0,01451872 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 13 13 1,000 1,127E-03 0,0144179 ! regulation of endothelial cell migration GO:0010594 13 13 1,000 1,127E-03 0,01431847 ! response to endoplasmic reticulum stress GO:0034976 13 13 1,000 1,127E-03 0,01422039 ! negative regulation of protein kinase cascade GO:0010741 13 13 1,000 1,127E-03 0,01412366 ! positive regulation of neurogenesis GO:0050769 13 13 1,000 1,127E-03 0,01402823 ! positive regulation of locomotion GO:0040017 13 13 1,000 1,127E-03 0,01393408 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, GO:0050920|regulation of chemotaxis, ! negative regulation of leukocyte activation GO:0002695 13 13 1,000 1,127E-03 0,01384118 ! regulation of cell-substrate adhesion GO:0010810 14 13 1,000 1,127E-03 0,01374952 GO:0001952|regulation of cell-matrix adhesion, ! response to oxygen levels GO:0070482 55 54 2,000 1,17E-03 0,01418877 ! regulation of cell adhesion GO:0030155 56 55 2,000 1,234E-03 0,01487037 ! regulation of nervous system development GO:0051960 57 56 2,000 1,301E-03 0,01556934 ! protein amino acid acylation GO:0043543 14 14 1,000 1,311E-03 0,01558936 ! hair cycle GO:0042633 14 14 1,000 1,311E-03 0,01548942 GO:0022404|molting cycle process, GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042303|molting cycle, ! regulation of behavior GO:0050795 14 14 1,000 1,311E-03 0,01539077 ! base-excision repair GO:0006284 14 14 1,000 1,311E-03 0,01529336 ! protein import into nucleus, translocation GO:0000060 15 15 1,000 1,509E-03 0,01749281 ! regulation of transcription factor import into nucleus GO:0042990 15 15 1,000 1,509E-03 0,01738348 ! insulin receptor signaling pathway GO:0008286 17 15 1,000 1,509E-03 0,0172755 ! ER-nuclear signaling pathway GO:0006984 15 15 1,000 1,509E-03 0,01716887 ! response to starvation GO:0042594 15 15 1,000 1,509E-03 0,01706354 ! response to ionizing radiation GO:0010212 16 15 1,000 1,509E-03 0,01695949 ! negative regulation of cell activation GO:0050866 15 15 1,000 1,509E-03 0,0168567 ! protein homooligomerization GO:0051260 15 15 1,000 1,509E-03 0,01675516 ! peptidyl-amino acid modification GO:0018193 61 59 2,000 1,514E-03 0,01670636 ! regulation of cell development GO:0060284 60 59 2,000 1,514E-03 0,01660692 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 16 16 1,000 1,721E-03 0,01876337 ! segmentation GO:0035282 17 16 1,000 1,721E-03 0,018653 ! fatty acid beta-oxidation GO:0006635 16 16 1,000 1,721E-03 0,01854392 ! positive regulation of cell development GO:0010720 16 16 1,000 1,721E-03 0,0184361 ! fatty acid transport GO:0015908 16 16 1,000 1,721E-03 0,01832954 ! cellular response to nutrient levels GO:0031669 16 16 1,000 1,721E-03 0,0182242 ! polyol metabolic process GO:0019751 16 16 1,000 1,721E-03 0,01812006 ! positive regulation of catabolic process GO:0009896 16 16 1,000 1,721E-03 0,0180171 ! regulation of cellular component biogenesis GO:0044087 63 62 2,000 1,747E-03 0,01819453 ! regulation of fibroblast proliferation GO:0048145 17 17 1,000 1,945E-03 0,02014116 ! regulation of smooth muscle cell proliferation GO:0048660 17 17 1,000 1,945E-03 0,02002864 ! positive regulation of cell adhesion GO:0045785 17 17 1,000 1,945E-03 0,01991737 ! myelination GO:0042552 17 17 1,000 1,945E-03 0,01980733 ! glucose transport GO:0015758 17 17 1,000 1,945E-03 0,0196985 ! tissue remodeling GO:0048771 17 17 1,000 1,945E-03 0,01959086 ! negative regulation of cell development GO:0010721 18 17 1,000 1,945E-03 0,01948438 GO:0050768|negative regulation of neurogenesis, ! regulation of oxidoreductase activity GO:0051341 17 17 1,000 1,945E-03 0,01937906 ! regulation of cell projection organization GO:0031344 19 18 1,000 2,183E-03 0,02163184 ! regulation of cellular catabolic process GO:0031329 18 18 1,000 2,183E-03 0,02151617 ! epidermal growth factor receptor signaling pathway GO:0007173 18 18 1,000 2,183E-03 0,02140172 ! hexose transport GO:0008645 18 18 1,000 2,183E-03 0,02128848 GO:0015749|monosaccharide transport, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 18 18 1,000 2,183E-03 0,02117644 ! B cell differentiation GO:0030183 18 18 1,000 2,183E-03 0,02106557 ! cellular response to extracellular stimulus GO:0031668 18 18 1,000 2,183E-03 0,02095585 ! symbiosis, encompassing mutualism through parasitism GO:0044403 18 18 1,000 2,183E-03 0,02084727 ! response to radiation GO:0009314 70 68 2,000 2,28E-03 0,02165533 ! DNA damage checkpoint GO:0000077 19 19 1,000 2,434E-03 0,02300521 ! negative regulation of DNA metabolic process GO:0051053 19 19 1,000 2,434E-03 0,02288784 ! regulation of pH GO:0006885 19 19 1,000 2,434E-03 0,02277166 ! regulation of endothelial cell proliferation GO:0001936 19 19 1,000 2,434E-03 0,02265665 ! peptidyl-tyrosine phosphorylation GO:0018108 20 19 1,000 2,434E-03 0,0225428 ! peripheral nervous system development GO:0007422 19 19 1,000 2,434E-03 0,02243008 ! regulation of protein stability GO:0031647 19 19 1,000 2,434E-03 0,02231849 ! regulation of cell shape GO:0008360 21 19 1,000 2,434E-03 0,022208 ! placenta development GO:0001890 19 19 1,000 2,434E-03 0,0220986 ! wound healing GO:0042060 74 70 2,000 2,477E-03 0,0223768 ! positive regulation of hydrolase activity GO:0051345 72 72 2,000 2,685E-03 0,02413463 ! negative regulation of cell adhesion GO:0007162 21 20 1,000 2,698E-03 0,02413798 ! positive regulation of gene-specific transcription GO:0043193 20 20 1,000 2,698E-03 0,02402138 ! peptidyl-tyrosine modification GO:0018212 21 20 1,000 2,698E-03 0,02390589 ! lipid oxidation GO:0034440 20 20 1,000 2,698E-03 0,02379151 GO:0019395|fatty acid oxidation, ! G1/S transition of mitotic cell cycle GO:0000082 21 21 1,000 2,975E-03 0,02610746 ! mammary gland development GO:0030879 23 21 1,000 2,975E-03 0,02598373 ! Notch signaling pathway GO:0007219 22 21 1,000 2,975E-03 0,02586117 ! morphogenesis of embryonic epithelium GO:0016331 22 21 1,000 2,975E-03 0,02573975 ! DNA integrity checkpoint GO:0031570 21 21 1,000 2,975E-03 0,02561947 ! regulation of protein import into nucleus GO:0042306 21 21 1,000 2,975E-03 0,02550031 ! negative regulation of hydrolase activity GO:0051346 21 21 1,000 2,975E-03 0,02538226 ! cellular response to insulin stimulus GO:0032869 23 21 1,000 2,975E-03 0,02526529 ! cell morphogenesis involved in differentiation GO:0000904 82 77 2,000 3,25E-03 0,02747577 ! positive regulation of transcription factor activity GO:0051091 22 22 1,000 3,264E-03 0,02747153 GO:0090047|positive regulation of transcription regulator activity, ! positive regulation of DNA metabolic process GO:0051054 23 22 1,000 3,264E-03 0,02734666 ! fatty acid catabolic process GO:0009062 23 22 1,000 3,264E-03 0,02722292 ! mitotic cell cycle checkpoint GO:0007093 24 23 1,000 3,567E-03 0,02960964 ! positive regulation of growth GO:0045927 23 23 1,000 3,567E-03 0,02947686 ! monovalent inorganic cation homeostasis GO:0055067 23 23 1,000 3,567E-03 0,02934526 ! calcium-mediated signaling GO:0019722 23 23 1,000 3,567E-03 0,02921484 ! neuron projection development GO:0031175 85 80 2,000 3,622E-03 0,02953562 ! MAPKKK cascade GO:0000165 82 81 2,000 3,751E-03 0,03045697 ! tube development GO:0035295 83 81 2,000 3,751E-03 0,03032338 ! mitochondrial transport GO:0006839 24 24 1,000 3,882E-03 0,03123848 ! glucose homeostasis GO:0042593 24 24 1,000 3,882E-03 0,03110266 GO:0033500|carbohydrate homeostasis, ! T cell differentiation GO:0030217 24 24 1,000 3,882E-03 0,03096801 ! androgen receptor signaling pathway GO:0030521 24 24 1,000 3,882E-03 0,03083453 ! regulation of intracellular protein transport GO:0033157 25 25 1,000 4,209E-03 0,03329143 ! regulation of T cell proliferation GO:0042129 25 25 1,000 4,209E-03 0,03314916 ! positive regulation of DNA binding GO:0043388 26 25 1,000 4,209E-03 0,0330081 ! heart morphogenesis GO:0003007 25 25 1,000 4,209E-03 0,03286824 ! negative regulation of immune system process GO:0002683 25 25 1,000 4,209E-03 0,03272955 ! JAK-STAT cascade GO:0007259 26 25 1,000 4,209E-03 0,03259203 ! positive regulation of cell differentiation GO:0045597 87 85 2,000 4,298E-03 0,03314055 ! regulation of anatomical structure morphogenesis GO:0022603 90 86 2,000 4,441E-03 0,03410631 ! positive regulation of binding GO:0051099 27 26 1,000 4,549E-03 0,03478441 ! negative regulation of cell migration GO:0030336 26 26 1,000 4,549E-03 0,03464067 ! induction of apoptosis by intracellular signals GO:0008629 26 26 1,000 4,549E-03 0,03449812 ! regulation of T cell differentiation GO:0045580 26 26 1,000 4,549E-03 0,03435673 ! double-strand break repair GO:0006302 27 26 1,000 4,549E-03 0,0342165 ! response to insulin stimulus GO:0032868 28 26 1,000 4,549E-03 0,03407741 ! synapse organization GO:0050808 26 26 1,000 4,549E-03 0,03393944 ! regulation of nucleocytoplasmic transport GO:0046822 27 27 1,000 4,901E-03 0,03641876 ! monocarboxylic acid transport GO:0015718 27 27 1,000 4,901E-03 0,0362725 ! activation of caspase activity GO:0006919 27 27 1,000 4,901E-03 0,03612741 ! mesenchymal cell development GO:0014031 29 27 1,000 4,901E-03 0,03598347 GO:0060485|mesenchyme development, GO:0048762|mesenchymal cell differentiation, ! isoprenoid metabolic process GO:0006720 27 27 1,000 4,901E-03 0,03584068 ! carbohydrate transport GO:0008643 28 28 1,000 5,265E-03 0,0383524 ! histone modification GO:0016570 28 28 1,000 5,265E-03 0,0382014 ! developmental growth GO:0048589 28 28 1,000 5,265E-03 0,0380516 ! regulation of mast cell proliferation GO:0070666 28 28 1,000 5,265E-03 0,03790296 ! positive regulation of cell cycle GO:0045787 29 29 1,000 5,641E-03 0,04045442 ! viral reproductive process GO:0022415 29 29 1,000 5,641E-03 0,04029762 ! phosphoinositide metabolic process GO:0030384 29 29 1,000 5,641E-03 0,04014203 ! regulation of lymphocyte proliferation GO:0050670 29 29 1,000 5,641E-03 0,03998763 GO:0032944|regulation of mononuclear cell proliferation, GO:0070663|regulation of leukocyte proliferation, ! covalent chromatin modification GO:0016569 29 29 1,000 5,641E-03 0,03983443 ! positive regulation of protein transport GO:0051222 29 29 1,000 5,641E-03 0,03968239 ! positive regulation of peptidase activity GO:0010952 30 30 1,000 6,03E-03 0,0422531 GO:0043280|positive regulation of caspase activity, ! activation of phospholipase C activity GO:0007202 30 30 1,000 6,03E-03 0,04209305 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of response to external stimulus GO:0032103 30 30 1,000 6,03E-03 0,0419342 ! vascular process in circulatory system GO:0003018 31 30 1,000 6,03E-03 0,04177656 ! posttranscriptional regulation of gene expression GO:0010608 98 98 2,000 6,398E-03 0,04416 ! skeletal muscle fiber development GO:0048741 31 31 1,000 6,43E-03 0,04421762 ! B cell activation GO:0042113 31 31 1,000 6,43E-03 0,04405325 ! positive regulation of phospholipase activity GO:0010518 31 31 1,000 6,43E-03 0,04389009 ! aging GO:0007568 32 31 1,000 6,43E-03 0,04372813 ! regulation of intracellular transport GO:0032386 31 31 1,000 6,43E-03 0,04356736 ! negative regulation of cell motion GO:0051271 31 31 1,000 6,43E-03 0,04340778 ! negative regulation of transcription from RNA polymerase II promoter GO:0000122 103 100 2,000 6,766E-03 0,04551139 ! negative regulation of cell growth GO:0030308 32 32 1,000 6,842E-03 0,04585415 ! muscle fiber development GO:0048747 32 32 1,000 6,842E-03 0,04568801 ! regulation of phospholipase activity GO:0010517 32 32 1,000 6,842E-03 0,04552307 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 32 32 1,000 6,842E-03 0,04535932 ! regulation of lymphocyte differentiation GO:0045619 32 32 1,000 6,842E-03 0,04519674 ! positive regulation of lipase activity GO:0060193 32 32 1,000 6,842E-03 0,04503533 ! negative regulation of cell size GO:0045792 33 33 1,000 7,266E-03 0,04765516 ! activation of protein kinase activity GO:0032147 35 33 1,000 7,266E-03 0,04748617 ! regulation of neuron apoptosis GO:0043523 34 33 1,000 7,266E-03 0,04731837 ! regulation of angiogenesis GO:0045765 35 34 1,000 7,701E-03 0,04997809 ! regulation of bone remodeling GO:0046850 34 34 1,000 7,701E-03 0,04980273 ! response to peptide hormone stimulus GO:0043434 36 34 1,000 7,701E-03 0,0496286 ! viral reproduction GO:0016032 34 34 1,000 7,701E-03 0,04945567 ! regulation of cell morphogenesis GO:0022604 38 35 1,000 8,149E-03 0,052145 ! positive regulation of phosphorylation GO:0042327 35 35 1,000 8,149E-03 0,05196457 ! regulation of tissue remodeling GO:0034103 35 35 1,000 8,149E-03 0,05178538 ! positive regulation of phosphorus metabolic process GO:0010562 36 36 1,000 8,607E-03 0,05451162 GO:0045937|positive regulation of phosphate metabolic process, ! female pregnancy GO:0007565 37 36 1,000 8,607E-03 0,05432493 ! regulation of lipase activity GO:0060191 36 36 1,000 8,607E-03 0,05413952 ! regulation of transcription factor activity GO:0051090 38 37 1,000 9,077E-03 0,05690126 GO:0090046|regulation of transcription regulator activity, ! response to drug GO:0042493 37 37 1,000 9,077E-03 0,05670838 ! negative regulation of growth GO:0045926 37 37 1,000 9,077E-03 0,05651679 ! DNA damage response, signal transduction GO:0042770 37 37 1,000 9,077E-03 0,0563265 ! adaptive immune response GO:0002250 37 37 1,000 9,077E-03 0,05613749 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! exocytosis GO:0006887 40 38 1,000 9,558E-03 0,05891595 ! axon guidance GO:0007411 39 38 1,000 9,558E-03 0,05871956 ! steroid hormone receptor signaling pathway GO:0030518 38 38 1,000 9,558E-03 0,05852448 ! regulation of homeostatic process GO:0032844 38 38 1,000 9,558E-03 0,05833069 ! activation of MAPK activity GO:0000187 39 39 1,000 0,01005068 0,06113335 ! nucleotide-excision repair GO:0006289 40 39 1,000 0,01005068 0,06093226 ! developmental maturation GO:0021700 39 39 1,000 0,01005068 0,06073248 ! lymphocyte differentiation GO:0030098 39 39 1,000 0,01005068 0,06053401 ! intracellular receptor-mediated signaling pathway GO:0030522 40 40 1,000 0,01055422 0,06335969 ! cell cycle checkpoint GO:0000075 42 41 1,000 0,01106878 0,06623298 ! cell-substrate adhesion GO:0031589 43 42 1,000 0,01159427 0,0691529 ! protein ubiquitination GO:0016567 43 42 1,000 0,01159427 0,06892983 ! mitochondrion organization GO:0007005 44 43 1,000 0,01213062 0,07188659 ! protein import into nucleus GO:0006606 44 44 1,000 0,01267773 0,07488797 ! vitamin metabolic process GO:0006766 44 44 1,000 0,01267773 0,07464871 ! homophilic cell adhesion GO:0007156 45 45 1,000 0,01323551 0,07768485 ! regulation of DNA binding GO:0051101 47 45 1,000 0,01323551 0,07743823 ! phosphoinositide-mediated signaling GO:0048015 45 45 1,000 0,01323551 0,07719317 ! nuclear import GO:0051170 45 45 1,000 0,01323551 0,07694966 ! Wnt receptor signaling pathway GO:0016055 46 45 1,000 0,01323551 0,07670768 ! cellular response to hormone stimulus GO:0032870 48 46 1,000 0,01380388 0,07975095 ! regulation of catabolic process GO:0009894 48 47 1,000 0,01438276 0,08283571 ! glycerophospholipid metabolic process GO:0006650 49 48 1,000 0,01497206 0,08596107 ! protein localization in nucleus GO:0034504 48 48 1,000 0,01497206 0,08569411 ! leukocyte differentiation GO:0002521 50 49 1,000 0,01557169 0,08885025 ! ossification GO:0001503 50 49 1,000 0,01557169 0,08857602 GO:0060348|bone development, ! gland development GO:0048732 51 49 1,000 0,01557169 0,08830348 ! cellular lipid catabolic process GO:0044242 50 49 1,000 0,01557169 0,08803261 ! T cell activation GO:0042110 51 50 1,000 0,01618158 0,09120077 ! anterior/posterior pattern formation GO:0009952 51 50 1,000 0,01618158 0,09092272 ! protein modification by small protein conjugation GO:0032446 52 51 1,000 0,01680164 0,0941198 ! cholesterol metabolic process GO:0008203 52 52 1,000 0,01743178 0,09735384 ! cell fate commitment GO:0045165 52 52 1,000 0,01743178 0,09705972 ! regulation of T cell activation GO:0050863 53 53 1,000 0,01807192 0,10032094 ! regulation of protein transport GO:0051223 53 53 1,000 0,01807192 0,10001968 GO:0070201|regulation of establishment of protein localization, ! protein amino acid dephosphorylation GO:0006470 55 54 1,000 0,01872199 0,10330726 ! response to virus GO:0009615 54 54 1,000 0,01872199 0,10299888 ! negative regulation of multicellular organismal process GO:0051241 55 54 1,000 0,01872199 0,10269233 ! microtubule cytoskeleton organization GO:0000226 55 55 1,000 0,01938189 0,10599653 ! in utero embryonic development GO:0001701 55 55 1,000 0,01938189 0,10568293 ! protein modification by small protein conjugation or removal GO:0070647 56 55 1,000 0,01938189 0,10537118 ! rRNA transcription GO:0009303 5 5 0,000 0,0194743 0,10556218 ! positive regulation of protein ubiquitination GO:0031398 5 5 0,000 0,0194743 0,10525261 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 5 5 0,000 0,0194743 0,10494486 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 5 5 0,000 0,0194743 0,10463889 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! neuron fate specification GO:0048665 5 5 0,000 0,0194743 0,10433471 ! hemoglobin biosynthetic process GO:0042541 5 5 0,000 0,0194743 0,10403229 ! reproductive cellular process GO:0048610 5 5 0,000 0,0194743 0,10373162 ! negative regulation of blood pressure GO:0045776 6 5 0,000 0,0194743 0,10343268 ! prostate gland development GO:0030850 5 5 0,000 0,0194743 0,10313546 ! metencephalon development GO:0022037 5 5 0,000 0,0194743 0,10283994 ! water transport GO:0006833 5 5 0,000 0,0194743 0,10254612 GO:0042044|fluid transport, ! forebrain regionalization GO:0021871 5 5 0,000 0,0194743 0,10225396 ! DNA synthesis during DNA repair GO:0000731 5 5 0,000 0,0194743 0,10196347 ! positive regulation of B cell proliferation GO:0030890 5 5 0,000 0,0194743 0,10167462 ! glycerol metabolic process GO:0006071 5 5 0,000 0,0194743 0,1013874 ! regulation of cellular amine metabolic process GO:0033238 5 5 0,000 0,0194743 0,1011018 GO:0042053|regulation of dopamine metabolic process, GO:0042069|regulation of catecholamine metabolic process, ! meiotic prophase I GO:0007128 5 5 0,000 0,0194743 0,10081781 GO:0051324|prophase, ! cell volume homeostasis GO:0006884 5 5 0,000 0,0194743 0,10053541 ! regulation of epidermal growth factor receptor activity GO:0007176 5 5 0,000 0,0194743 0,10025458 GO:0010469|regulation of receptor activity, ! regulation of long-term neuronal synaptic plasticity GO:0048169 5 5 0,000 0,0194743 0,09997532 ! filopodium assembly GO:0046847 7 5 0,000 0,0194743 0,09969761 GO:0030035|microspike assembly, ! CTP metabolic process GO:0046036 5 5 0,000 0,0194743 0,09942144 GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0006241|CTP biosynthetic process, ! Golgi to endosome transport GO:0006895 5 5 0,000 0,0194743 0,0991468 ! GTP metabolic process GO:0046039 5 5 0,000 0,0194743 0,09887367 ! establishment of tissue polarity GO:0007164 5 5 0,000 0,0194743 0,09860203 ! positive regulation of cell-cell adhesion GO:0022409 5 5 0,000 0,0194743 0,09833189 ! regulation of neurotransmitter secretion GO:0046928 5 5 0,000 0,0194743 0,09806323 GO:0001956|positive regulation of neurotransmitter secretion, ! neurotransmitter uptake GO:0001504 5 5 0,000 0,0194743 0,09779602 ! social behavior GO:0035176 5 5 0,000 0,0194743 0,09753027 ! macrophage chemotaxis GO:0048246 6 5 0,000 0,0194743 0,09726596 ! 2-oxoglutarate metabolic process GO:0006103 5 5 0,000 0,0194743 0,09700308 ! memory GO:0007613 5 5 0,000 0,0194743 0,09674162 ! dopamine receptor signaling pathway GO:0007212 5 5 0,000 0,0194743 0,09648156 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 5 5 0,000 0,0194743 0,0962229 ! membrane hyperpolarization GO:0060081 5 5 0,000 0,0194743 0,09596562 ! response to lipid GO:0033993 5 5 0,000 0,0194743 0,09570971 ! erythrocyte maturation GO:0043249 5 5 0,000 0,0194743 0,09545516 ! hippocampus development GO:0021766 6 5 0,000 0,0194743 0,09520196 ! regulation of carbohydrate biosynthetic process GO:0043255 5 5 0,000 0,0194743 0,09495011 ! glucocorticoid metabolic process GO:0008211 5 5 0,000 0,0194743 0,09469958 ! middle ear morphogenesis GO:0042474 5 5 0,000 0,0194743 0,09445037 ! amyloid precursor protein catabolic process GO:0042987 5 5 0,000 0,0194743 0,09420247 ! mechanosensory behavior GO:0007638 5 5 0,000 0,0194743 0,09395587 ! heart looping GO:0001947 5 5 0,000 0,0194743 0,09371055 ! negative regulation of endocytosis GO:0045806 5 5 0,000 0,0194743 0,09346651 ! response to interferon-gamma GO:0034341 5 5 0,000 0,0194743 0,09322374 ! pseudouridine synthesis GO:0001522 5 5 0,000 0,0194743 0,09298223 ! endocrine pancreas development GO:0031018 5 5 0,000 0,0194743 0,09274197 ! pH reduction GO:0045851 5 5 0,000 0,0194743 0,09250294 GO:0051452|intracellular pH reduction, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 5 5 0,000 0,0194743 0,09226514 ! lipopolysaccharide metabolic process GO:0008653 5 5 0,000 0,0194743 0,09202857 ! positive regulation of chemokine biosynthetic process GO:0045080 5 5 0,000 0,0194743 0,0917932 ! sphingoid biosynthetic process GO:0046520 5 5 0,000 0,0194743 0,09155903 GO:0046513|ceramide biosynthetic process, ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 5 5 0,000 0,0194743 0,09132606 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! thymic T cell selection GO:0045061 5 5 0,000 0,0194743 0,09109427 ! insulin-like growth factor receptor signaling pathway GO:0048009 5 5 0,000 0,0194743 0,09086365 ! photoreceptor cell maintenance GO:0045494 5 5 0,000 0,0194743 0,09063419 ! adrenal gland development GO:0030325 5 5 0,000 0,0194743 0,0904059 ! regulation of cardiac muscle hypertrophy GO:0010611 5 5 0,000 0,0194743 0,09017875 GO:0010612|regulation of cardiac muscle adaptation, GO:0014743|regulation of muscle hypertrophy, GO:0043502|regulation of muscle adaptation, ! melanocyte differentiation GO:0030318 5 5 0,000 0,0194743 0,08995273 GO:0050931|pigment cell differentiation, ! ovulation GO:0030728 5 5 0,000 0,0194743 0,08972785 ! astrocyte differentiation GO:0048708 5 5 0,000 0,0194743 0,08950409 ! mitochondrial respiratory chain complex assembly GO:0033108 5 5 0,000 0,0194743 0,08928144 GO:0032981|mitochondrial respiratory chain complex I assembly, GO:0010257|NADH dehydrogenase complex assembly, ! pituitary gland development GO:0021983 5 5 0,000 0,0194743 0,0890599 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 5 5 0,000 0,0194743 0,08883946 GO:0033135|regulation of peptidyl-serine phosphorylation, ! tyrosine metabolic process GO:0006570 5 5 0,000 0,0194743 0,0886201 ! cytoskeletal anchoring at plasma membrane GO:0007016 6 5 0,000 0,0194743 0,08840182 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 5 5 0,000 0,0194743 0,08818462 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, GO:0009164|nucleoside catabolic process, ! microtubule nucleation GO:0007020 5 5 0,000 0,0194743 0,08796848 ! regulation of interleukin-6 biosynthetic process GO:0045408 5 5 0,000 0,0194743 0,0877534 ! regulation of interleukin-8 biosynthetic process GO:0045414 5 5 0,000 0,0194743 0,08753937 ! indolalkylamine metabolic process GO:0006586 5 5 0,000 0,0194743 0,08732638 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! muscle cell migration GO:0014812 5 5 0,000 0,0194743 0,08711442 ! phasic smooth muscle contraction GO:0014821 5 5 0,000 0,0194743 0,08690349 ! central nervous system neuron axonogenesis GO:0021955 6 5 0,000 0,0194743 0,08669358 GO:0021952|central nervous system projection neuron axonogenesis, ! sister chromatid cohesion GO:0007062 5 5 0,000 0,0194743 0,08648468 ! response to ATP GO:0033198 5 5 0,000 0,0194743 0,08627678 ! regulation of type I interferon production GO:0032479 5 5 0,000 0,0194743 0,08606988 ! regulation of appetite GO:0032098 5 5 0,000 0,0194743 0,08586397 GO:0032095|regulation of response to food, ! vesicle fusion GO:0006906 5 5 0,000 0,0194743 0,08565905 ! paraxial mesoderm development GO:0048339 5 5 0,000 0,0194743 0,0854551 ! regulation of the force of heart contraction GO:0002026 5 5 0,000 0,0194743 0,08525212 ! maintenance of protein location in nucleus GO:0051457 5 5 0,000 0,0194743 0,0850501 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,0194743 0,08484903 ! receptor clustering GO:0043113 5 5 0,000 0,0194743 0,08464892 ! neurotransmitter biosynthetic process GO:0042136 6 5 0,000 0,0194743 0,08444974 ! fear response GO:0042596 5 5 0,000 0,0194743 0,0842515 ! lens development in camera-type eye GO:0002088 5 5 0,000 0,0194743 0,08405419 ! retinol metabolic process GO:0042572 5 5 0,000 0,0194743 0,08385781 ! corticosteroid receptor signaling pathway GO:0031958 5 5 0,000 0,0194743 0,08366233 GO:0042921|glucocorticoid receptor signaling pathway, ! temperature homeostasis GO:0001659 5 5 0,000 0,0194743 0,08346777 ! positive regulation of exocytosis GO:0045921 6 5 0,000 0,0194743 0,08327411 ! parturition GO:0007567 5 5 0,000 0,0194743 0,08308134 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,0194743 0,08288947 ! regulation of vascular endothelial growth factor production GO:0010574 5 5 0,000 0,0194743 0,08269848 ! Schwann cell differentiation GO:0014037 5 5 0,000 0,0194743 0,08250837 ! acyl-CoA metabolic process GO:0006637 5 5 0,000 0,0194743 0,08231913 ! wound healing, spreading of epidermal cells GO:0035313 5 5 0,000 0,0194743 0,08213076 ! regulation of gliogenesis GO:0014013 5 5 0,000 0,0194743 0,08194324 GO:0045685|regulation of glial cell differentiation, ! positive regulation of peptide secretion GO:0002793 5 5 0,000 0,0194743 0,08175658 ! response to UV-B GO:0010224 5 5 0,000 0,0194743 0,08157077 ! oligodendrocyte development GO:0014003 5 5 0,000 0,0194743 0,08138581 ! hyaluronan metabolic process GO:0030212 5 5 0,000 0,0194743 0,08120168 ! activated T cell proliferation GO:0050798 5 5 0,000 0,0194743 0,08101838 ! interaction with symbiont GO:0051702 5 5 0,000 0,0194743 0,0808359 ! cellular extravasation GO:0045123 5 5 0,000 0,0194743 0,08065425 ! positive regulation of axonogenesis GO:0050772 5 5 0,000 0,0194743 0,08047341 ! peptidyl-asparagine modification GO:0018196 5 5 0,000 0,0194743 0,08029338 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! positive regulation of phagocytosis GO:0050766 5 5 0,000 0,0194743 0,08011415 ! regulation of insulin receptor signaling pathway GO:0046626 5 5 0,000 0,0194743 0,07993573 ! antigen processing and presentation of exogenous antigen GO:0019884 5 5 0,000 0,0194743 0,07975809 ! enucleate erythrocyte differentiation GO:0043353 6 5 0,000 0,0194743 0,07958124 ! response to amine stimulus GO:0014075 5 5 0,000 0,0194743 0,07940518 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 5 5 0,000 0,0194743 0,07922989 ! synaptic vesicle exocytosis GO:0016079 6 5 0,000 0,0194743 0,07905538 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 5 5 0,000 0,0194743 0,07888163 ! glycosylceramide metabolic process GO:0006677 5 5 0,000 0,0194743 0,07870864 ! neuron recognition GO:0008038 5 5 0,000 0,0194743 0,07853641 ! phosphatidylinositol biosynthetic process GO:0006661 5 5 0,000 0,0194743 0,07836494 ! regulation of mitochondrial membrane potential GO:0051881 5 5 0,000 0,0194743 0,07819421 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 0,0194743 0,07802422 GO:0009155|purine deoxyribonucleotide catabolic process, ! regulation of interleukin-12 production GO:0032655 5 5 0,000 0,0194743 0,07785497 ! positive regulation of interleukin-6 production GO:0032755 5 5 0,000 0,0194743 0,07768645 ! positive regulation of monooxygenase activity GO:0032770 5 5 0,000 0,0194743 0,07751866 ! postreplication repair GO:0006301 5 5 0,000 0,0194743 0,0773516 ! spinal cord motor neuron differentiation GO:0021522 5 5 0,000 0,0194743 0,07718525 GO:0021517|ventral spinal cord development, ! cellular pigmentation GO:0033059 5 5 0,000 0,0194743 0,07701962 ! histone methylation GO:0016571 5 5 0,000 0,0194743 0,07685469 ! DNA methylation GO:0006306 5 5 0,000 0,0194743 0,07669047 GO:0006305|DNA alkylation, ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,0194743 0,07652695 ! positive regulation of immunoglobulin mediated immune response GO:0002891 5 5 0,000 0,0194743 0,07636413 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of interferon-gamma production GO:0032729 5 5 0,000 0,0194743 0,076202 ! negative regulation of tumor necrosis factor production GO:0032720 5 5 0,000 0,0194743 0,07604055 ! intracellular cholesterol transport GO:0032367 5 5 0,000 0,0194743 0,07587979 GO:0032366|intracellular sterol transport, ! regulation of mast cell activation GO:0033003 5 5 0,000 0,0194743 0,07571971 ! morphogenesis of a polarized epithelium GO:0001738 5 5 0,000 0,0194743 0,0755603 ! regulation of hormone metabolic process GO:0032350 5 5 0,000 0,0194743 0,07540156 ! regulation of transcription from RNA polymerase III promoter GO:0006359 5 5 0,000 0,0194743 0,07524348 ! regulation of inflammatory response to antigenic stimulus GO:0002861 5 5 0,000 0,0194743 0,07508607 ! sterol catabolic process GO:0016127 5 5 0,000 0,0194743 0,07492931 GO:0006707|cholesterol catabolic process, ! negative regulation of oxidoreductase activity GO:0051354 5 5 0,000 0,0194743 0,07477321 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 5 5 0,000 0,0194743 0,07461776 ! detection of biotic stimulus GO:0009595 5 5 0,000 0,0194743 0,07446295 ! regulation of immune response to tumor cell GO:0002837 5 5 0,000 0,0194743 0,07430878 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 5 5 0,000 0,0194743 0,07415525 ! zymogen activation GO:0031638 5 5 0,000 0,0194743 0,07400235 ! positive regulation of interleukin-1 beta secretion GO:0050718 5 5 0,000 0,0194743 0,07385008 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 5 5 0,000 0,0194743 0,07369844 GO:0002820|negative regulation of adaptive immune response, ! cellular response to nutrient GO:0031670 5 5 0,000 0,0194743 0,07354742 ! peptidyl-histidine modification GO:0018202 5 5 0,000 0,0194743 0,07339702 ! nucleosome positioning GO:0016584 5 5 0,000 0,0194743 0,07324723 ! regulation of isotype switching GO:0045191 5 5 0,000 0,0194743 0,07309805 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 5 5 0,000 0,0194743 0,07294947 ! negative regulation of neurological system process GO:0031645 5 5 0,000 0,0194743 0,0728015 ! regulation of myoblast differentiation GO:0045661 5 5 0,000 0,0194743 0,07265413 ! glutathione biosynthetic process GO:0006750 5 5 0,000 0,0194743 0,07250735 ! NADPH regeneration GO:0006740 5 5 0,000 0,0194743 0,07236117 GO:0006098|pentose-phosphate shunt, ! positive regulation of erythrocyte differentiation GO:0045648 5 5 0,000 0,0194743 0,07221557 ! positive regulation of epidermis development GO:0045684 5 5 0,000 0,0194743 0,07207056 ! positive regulation of leukocyte chemotaxis GO:0002690 5 5 0,000 0,0194743 0,07192613 GO:0002688|regulation of leukocyte chemotaxis, ! musculoskeletal movement GO:0050881 5 5 0,000 0,0194743 0,07178228 GO:0050879|multicellular organismal movement, ! neuromuscular process controlling posture GO:0050884 5 5 0,000 0,0194743 0,071639 ! sarcomere organization GO:0045214 5 5 0,000 0,0194743 0,0714963 ! regulation of epidermal cell differentiation GO:0045604 5 5 0,000 0,0194743 0,07135416 ! activation of NF-kappaB-inducing kinase activity GO:0007250 5 5 0,000 0,0194743 0,07121258 ! negative regulation of glucose transport GO:0010829 5 5 0,000 0,0194743 0,07107157 GO:0046325|negative regulation of glucose import, ! positive regulation of T-helper cell differentiation GO:0045624 5 5 0,000 0,0194743 0,07093111 GO:0045622|regulation of T-helper cell differentiation, ! oocyte differentiation GO:0009994 5 5 0,000 0,0194743 0,0707912 GO:0048599|oocyte development, ! dopamine biosynthetic process GO:0042416 5 5 0,000 0,0194743 0,07065185 ! regulation of protein homodimerization activity GO:0043496 6 5 0,000 0,0194743 0,07051305 ! spleen development GO:0048536 5 5 0,000 0,0194743 0,07037479 ! male genitalia development GO:0030539 5 5 0,000 0,0194743 0,07023707 ! nicotinamide nucleotide biosynthetic process GO:0019359 5 5 0,000 0,0194743 0,07009988 ! quaternary ammonium group transport GO:0015697 5 5 0,000 0,0194743 0,06996324 ! thyroid hormone metabolic process GO:0042403 5 5 0,000 0,0194743 0,06982712 ! leukocyte mediated cytotoxicity GO:0001909 5 5 0,000 0,0194743 0,06969154 ! positive regulation of viral reproduction GO:0048524 5 5 0,000 0,0194743 0,06955647 ! removal of superoxide radicals GO:0019430 6 5 0,000 0,0194743 0,06942194 ! myeloid cell homeostasis GO:0002262 5 5 0,000 0,0194743 0,06928792 ! regulation of fatty acid oxidation GO:0046320 5 5 0,000 0,0194743 0,06915441 ! regulation of Rac protein signal transduction GO:0035020 5 5 0,000 0,0194743 0,06902142 ! ATP catabolic process GO:0006200 5 5 0,000 0,0194743 0,06888895 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,0194743 0,06875697 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 5 5 0,000 0,0194743 0,06862551 ! blastocyst formation GO:0001825 5 5 0,000 0,0194743 0,06849454 ! regulation of fibrinolysis GO:0051917 5 5 0,000 0,0194743 0,06836408 ! embryonic gut development GO:0048566 5 5 0,000 0,0194743 0,06823411 ! negative regulation of organic acid transport GO:0032891 5 5 0,000 0,0194743 0,06810463 ! pyrimidine base metabolic process GO:0006206 5 5 0,000 0,0194743 0,06797565 ! activation of innate immune response GO:0002218 5 5 0,000 0,0194743 0,06784715 GO:0002758|innate immune response-activating signal transduction, ! catecholamine transport GO:0051937 5 5 0,000 0,0194743 0,06771913 ! negative regulation of blood vessel endothelial cell migration GO:0043537 5 5 0,000 0,0194743 0,0675916 ! regulation of NF-kappaB import into nucleus GO:0042345 5 5 0,000 0,0194743 0,06746455 ! muscle adaptation GO:0043500 5 5 0,000 0,0194743 0,06733798 ! positive regulation of actin filament bundle formation GO:0032233 5 5 0,000 0,0194743 0,06721187 ! embryonic heart tube development GO:0035050 5 5 0,000 0,0194743 0,06708624 ! cardiac cell differentiation GO:0035051 6 5 0,000 0,0194743 0,06696108 ! positive regulation of homeostatic process GO:0032846 5 5 0,000 0,0194743 0,06683639 ! defense response to fungus GO:0050832 5 5 0,000 0,0194743 0,06671216 ! lysogeny GO:0030069 5 5 0,000 0,0194743 0,06658839 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 5 5 0,000 0,0194743 0,06646508 ! B cell receptor signaling pathway GO:0050853 5 5 0,000 0,0194743 0,06634222 ! positive regulation of smooth muscle contraction GO:0045987 5 5 0,000 0,0194743 0,06621982 ! response to nicotine GO:0035094 5 5 0,000 0,0194743 0,06609787 ! establishment of cell polarity GO:0030010 5 5 0,000 0,0194743 0,06597636 ! mitochondrion localization GO:0051646 5 5 0,000 0,0194743 0,0658553 ! nucleus localization GO:0051647 5 5 0,000 0,0194743 0,06573469 ! regulation of synapse structure and activity GO:0050803 5 5 0,000 0,0194743 0,06561452 ! reproductive developmental process GO:0003006 56 56 1,000 0,02005156 0,06743617 ! extracellular structure organization GO:0043062 56 56 1,000 0,02005156 0,06731333 ! regulation of binding GO:0051098 60 57 1,000 0,0207309 0,06946736 ! regulation of protein localization GO:0032880 58 57 1,000 0,0207309 0,06934128 ! dephosphorylation GO:0016311 60 59 1,000 0,0221183 0,07384786 ! carboxylic acid transport GO:0046942 59 59 1,000 0,0221183 0,07371432 GO:0015849|organic acid transport, ! sterol metabolic process GO:0016125 59 59 1,000 0,0221183 0,07358126 ! protein localization in organelle GO:0033365 59 59 1,000 0,0221183 0,07344868 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 6 6 0,000 0,02332509 0,07731682 ! axon extension GO:0048675 7 6 0,000 0,02332509 0,07717801 ! oligosaccharide biosynthetic process GO:0009312 6 6 0,000 0,02332509 0,0770397 ! tRNA modification GO:0006400 6 6 0,000 0,02332509 0,07690188 ! somatic diversification of immune receptors via somatic mutation GO:0002566 6 6 0,000 0,02332509 0,07676455 GO:0016446|somatic hypermutation of immunoglobulin genes, ! 'de novo' posttranslational protein folding GO:0051084 6 6 0,000 0,02332509 0,07662772 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 6 6 0,000 0,02332509 0,07649137 ! negative regulation of cellular catabolic process GO:0031330 6 6 0,000 0,02332509 0,07635551 ! regulation of S phase GO:0033261 6 6 0,000 0,02332509 0,07622012 ! myotube differentiation GO:0014902 6 6 0,000 0,02332509 0,07608522 ! regulation of B cell proliferation GO:0030888 6 6 0,000 0,02332509 0,0759508 ! bone remodeling GO:0046849 6 6 0,000 0,02332509 0,07581684 ! N-glycan processing GO:0006491 6 6 0,000 0,02332509 0,07568336 ! regulation of lipid kinase activity GO:0043550 6 6 0,000 0,02332509 0,07555035 ! glycosaminoglycan catabolic process GO:0006027 6 6 0,000 0,02332509 0,07541781 ! negative regulation of JAK-STAT cascade GO:0046426 6 6 0,000 0,02332509 0,07528573 ! retina development in camera-type eye GO:0060041 6 6 0,000 0,02332509 0,07515411 ! RNA methylation GO:0001510 6 6 0,000 0,02332509 0,07502295 ! cartilage condensation GO:0001502 7 6 0,000 0,02332509 0,07489225 ! regulation of activated T cell proliferation GO:0046006 6 6 0,000 0,02332509 0,074762 ! succinate metabolic process GO:0006105 7 6 0,000 0,02332509 0,0746322 ! artery development GO:0060840 6 6 0,000 0,02332509 0,07450286 GO:0048844|artery morphogenesis, ! positive regulation of neurotransmitter transport GO:0051590 6 6 0,000 0,02332509 0,07437396 ! bile acid metabolic process GO:0008206 6 6 0,000 0,02332509 0,07424551 ! androgen metabolic process GO:0008209 6 6 0,000 0,02332509 0,0741175 ! estrogen metabolic process GO:0008210 6 6 0,000 0,02332509 0,07398993 ! limbic system development GO:0021761 7 6 0,000 0,02332509 0,0738628 ! cytoplasmic sequestering of transcription factor GO:0042994 6 6 0,000 0,02332509 0,07373611 ! positive regulation of heart contraction GO:0045823 6 6 0,000 0,02332509 0,07360985 ! positive regulation of gene expression, epigenetic GO:0045815 6 6 0,000 0,02332509 0,07348402 ! pathogenesis GO:0009405 6 6 0,000 0,02332509 0,07335862 ! negative regulation of protein amino acid phosphorylation GO:0001933 6 6 0,000 0,02332509 0,07323365 ! positive regulation of cell growth GO:0030307 6 6 0,000 0,02332509 0,0731091 ! ribonucleoside triphosphate catabolic process GO:0009203 6 6 0,000 0,02332509 0,07298497 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! regulation of chemokine biosynthetic process GO:0045073 6 6 0,000 0,02332509 0,07286127 ! nerve growth factor receptor signaling pathway GO:0048011 6 6 0,000 0,02332509 0,07273799 ! inositol phosphate-mediated signaling GO:0048016 6 6 0,000 0,02332509 0,07261512 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 6 6 0,000 0,02332509 0,07249266 ! arginine metabolic process GO:0006525 6 6 0,000 0,02332509 0,07237062 GO:0006527|arginine catabolic process, ! regulation of catecholamine secretion GO:0050433 6 6 0,000 0,02332509 0,07224899 ! oligodendrocyte differentiation GO:0048709 6 6 0,000 0,02332509 0,07212777 ! glutamate catabolic process GO:0006538 7 6 0,000 0,02332509 0,07200695 ! telomere maintenance via telomerase GO:0007004 6 6 0,000 0,02332509 0,07188654 GO:0010833|telomere maintenance via telomere lengthening, ! L-phenylalanine metabolic process GO:0006558 6 6 0,000 0,02332509 0,07176653 GO:0006559|L-phenylalanine catabolic process, ! glucan biosynthetic process GO:0009250 6 6 0,000 0,02332509 0,07164692 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 6 6 0,000 0,02332509 0,0715277 ! V(D)J recombination GO:0033151 6 6 0,000 0,02332509 0,07140889 ! focal adhesion formation GO:0048041 7 6 0,000 0,02332509 0,07129046 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 0,02332509 0,07117243 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 6 6 0,000 0,02332509 0,07105479 ! negative regulation of endothelial cell migration GO:0010596 6 6 0,000 0,02332509 0,07093754 ! regulation of heart rate GO:0002027 6 6 0,000 0,02332509 0,07082068 ! lipid digestion GO:0044241 6 6 0,000 0,02332509 0,07070419 ! asymmetric protein localization GO:0008105 6 6 0,000 0,02332509 0,0705881 ! retrograde transport, endosome to Golgi GO:0042147 6 6 0,000 0,02332509 0,07047238 ! phagocytosis, engulfment GO:0006911 6 6 0,000 0,02332509 0,07035704 ! Rac protein signal transduction GO:0016601 6 6 0,000 0,02332509 0,07024208 ! regulation of calcium ion transport into cytosol GO:0010522 6 6 0,000 0,02332509 0,07012749 ! ruffle organization GO:0031529 6 6 0,000 0,02332509 0,07001327 ! peptidyl-serine phosphorylation GO:0018105 6 6 0,000 0,02332509 0,06989943 ! preassembly of GPI anchor in ER membrane GO:0016254 6 6 0,000 0,02332509 0,06978596 ! retinoic acid metabolic process GO:0042573 6 6 0,000 0,02332509 0,06967285 ! neutral amino acid transport GO:0015804 6 6 0,000 0,02332509 0,06956011 ! L-amino acid transport GO:0015807 6 6 0,000 0,02332509 0,06944774 ! bone mineralization GO:0030282 6 6 0,000 0,02332509 0,06933573 GO:0031214|biomineral formation, ! rRNA modification GO:0000154 6 6 0,000 0,02332509 0,06922407 ! negative regulation of ossification GO:0030279 6 6 0,000 0,02332509 0,06911278 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 6 6 0,000 0,02332509 0,06900185 GO:0002717|positive regulation of natural killer cell mediated immunity, GO:0002715|regulation of natural killer cell mediated immunity, GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 7 6 0,000 0,02332509 0,06889127 ! purine base biosynthetic process GO:0009113 6 6 0,000 0,02332509 0,06878104 ! negative regulation of axonogenesis GO:0050771 7 6 0,000 0,02332509 0,06867117 ! regulation of phagocytosis GO:0050764 6 6 0,000 0,02332509 0,06856164 ! regulation of organ growth GO:0046620 6 6 0,000 0,02332509 0,06845247 ! regulation of circadian rhythm GO:0042752 6 6 0,000 0,02332509 0,06834364 ! positive regulation of T cell mediated immunity GO:0002711 6 6 0,000 0,02332509 0,06823516 ! response to dsRNA GO:0043331 6 6 0,000 0,02332509 0,06812702 ! DNA unwinding during replication GO:0006268 6 6 0,000 0,02332509 0,06801922 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 6 6 0,000 0,02332509 0,06791177 GO:0009147|pyrimidine nucleoside triphosphate metabolic process, ! genitalia development GO:0048806 6 6 0,000 0,02332509 0,06780465 ! sphingomyelin metabolic process GO:0006684 6 6 0,000 0,02332509 0,06769787 ! positive regulation of B cell differentiation GO:0045579 6 6 0,000 0,02332509 0,06759143 ! multicellular organismal aging GO:0010259 6 6 0,000 0,02332509 0,06748532 ! respiratory chain complex IV assembly GO:0008535 6 6 0,000 0,02332509 0,06737955 ! erythrocyte development GO:0048821 6 6 0,000 0,02332509 0,0672741 ! renal water homeostasis GO:0003091 6 6 0,000 0,02332509 0,06716898 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 6 6 0,000 0,02332509 0,0670642 GO:0043372|positive regulation of CD4-positive, alpha beta T cell differentiation, ! ribosomal large subunit biogenesis GO:0042273 6 6 0,000 0,02332509 0,06695974 ! regulation of Rho GTPase activity GO:0032319 6 6 0,000 0,02332509 0,0668556 ! ribosome assembly GO:0042255 6 6 0,000 0,02332509 0,06675179 ! positive regulation of Ras GTPase activity GO:0032320 6 6 0,000 0,02332509 0,06664829 ! diencephalon development GO:0021536 6 6 0,000 0,02332509 0,06654512 ! fucose catabolic process GO:0019317 6 6 0,000 0,02332509 0,06644227 GO:0042355|L-fucose catabolic process, ! nitric oxide metabolic process GO:0046209 6 6 0,000 0,02332509 0,06633974 GO:0006809|nitric oxide biosynthetic process, ! protein sumoylation GO:0016925 6 6 0,000 0,02332509 0,06623752 ! regulation of lipid transport GO:0032368 6 6 0,000 0,02332509 0,06613562 ! regulation of cell division GO:0051302 6 6 0,000 0,02332509 0,06603402 ! positive regulation of interleukin-1 secretion GO:0050716 6 6 0,000 0,02332509 0,06593275 ! cellular metabolic compound salvage GO:0043094 6 6 0,000 0,02332509 0,06583178 ! regulation of T-helper 2 type immune response GO:0002828 6 6 0,000 0,02332509 0,06573112 ! salivary gland morphogenesis GO:0007435 6 6 0,000 0,02332509 0,06563076 ! neuroblast proliferation GO:0007405 6 6 0,000 0,02332509 0,06553072 ! regulation of interleukin-1 beta secretion GO:0050706 6 6 0,000 0,02332509 0,06543097 ! nitric oxide mediated signal transduction GO:0007263 6 6 0,000 0,02332509 0,06533154 ! regulation of glucose transport GO:0010827 6 6 0,000 0,02332509 0,0652324 GO:0046324|regulation of glucose import, ! intestinal absorption GO:0050892 6 6 0,000 0,02332509 0,06513356 ! methionine biosynthetic process GO:0009086 6 6 0,000 0,02332509 0,06503502 ! glutamine family amino acid biosynthetic process GO:0009084 6 6 0,000 0,02332509 0,06493678 ! serine family amino acid biosynthetic process GO:0009070 6 6 0,000 0,02332509 0,06483884 ! thymus development GO:0048538 6 6 0,000 0,02332509 0,06474119 ! lymph node development GO:0048535 6 6 0,000 0,02332509 0,06464383 ! organic cation transport GO:0015695 6 6 0,000 0,02332509 0,06454677 ! negative regulation of BMP signaling pathway GO:0030514 6 6 0,000 0,02332509 0,06445 ! regulation of RNA splicing GO:0043484 6 6 0,000 0,02332509 0,06435352 ! positive regulation of JNK cascade GO:0046330 7 6 0,000 0,02332509 0,06425732 ! sperm-egg recognition GO:0035036 7 6 0,000 0,02332509 0,06416142 GO:0007339|binding of sperm to zona pellucida, ! germ cell migration GO:0008354 6 6 0,000 0,02332509 0,0640658 ! establishment or maintenance of apical/basal cell polarity GO:0035088 6 6 0,000 0,02332509 0,06397046 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 6 6 0,000 0,02332509 0,06387541 ! alditol metabolic process GO:0019400 6 6 0,000 0,02332509 0,06378064 ! regulation of synaptic transmission, GABAergic GO:0032228 6 6 0,000 0,02332509 0,06368615 ! regulation of amino acid transport GO:0051955 6 6 0,000 0,02332509 0,06359194 ! negative regulation of immune effector process GO:0002698 6 6 0,000 0,02332509 0,06349801 ! regulation of protein amino acid phosphorylation GO:0001932 62 61 1,000 0,02354345 0,06399789 ! carboxylic acid catabolic process GO:0046395 63 61 1,000 0,02354345 0,06390364 GO:0016054|organic acid catabolic process, ! lipid transport GO:0006869 62 62 1,000 0,02426998 0,06577879 ! morphogenesis of an epithelium GO:0002009 63 62 1,000 0,02426998 0,06568219 GO:0060429|epithelium development, ! axonogenesis GO:0007409 66 62 1,000 0,02426998 0,06558589 ! protein import GO:0017038 62 62 1,000 0,02426998 0,06548986 ! regulation of lymphocyte activation GO:0051249 62 62 1,000 0,02426998 0,06539411 ! negative regulation of cellular component organization GO:0051129 65 63 1,000 0,02500572 0,06727816 ! glucose metabolic process GO:0006006 63 63 1,000 0,02500572 0,06718009 ! glycerolipid metabolic process GO:0046486 65 64 1,000 0,02575058 0,06908053 ! regulation of response to external stimulus GO:0032101 65 64 1,000 0,02575058 0,06898012 ! positive regulation of cellular component organization GO:0051130 65 65 1,000 0,02650449 0,07089663 ! respiratory burst GO:0045730 7 7 0,000 0,02716132 0,07254828 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 7 7 0,000 0,02716132 0,07244329 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 7 7 0,000 0,02716132 0,07233861 ! negative regulation of cell projection organization GO:0031345 8 7 0,000 0,02716132 0,07223422 ! positive regulation of blood pressure GO:0045777 7 7 0,000 0,02716132 0,07213014 ! pteridine and derivative biosynthetic process GO:0042559 7 7 0,000 0,02716132 0,07202635 ! regulation of chemokine production GO:0032642 7 7 0,000 0,02716132 0,07192287 ! double-strand break repair via homologous recombination GO:0000724 7 7 0,000 0,02716132 0,07181968 GO:0000725|recombinational repair, ! positive regulation of GTPase activity GO:0043547 7 7 0,000 0,02716132 0,07171678 ! SMAD protein nuclear translocation GO:0007184 7 7 0,000 0,02716132 0,07161419 ! cellular protein complex disassembly GO:0043624 8 7 0,000 0,02716132 0,07151188 GO:0043241|protein complex disassembly, ! hair follicle morphogenesis GO:0031069 7 7 0,000 0,02716132 0,07140987 ! gene silencing by RNA GO:0031047 7 7 0,000 0,02716132 0,07130814 ! regulation of receptor-mediated endocytosis GO:0048259 7 7 0,000 0,02716132 0,07120671 ! oxaloacetate metabolic process GO:0006107 7 7 0,000 0,02716132 0,07110556 ! regulation of neurotransmitter transport GO:0051588 7 7 0,000 0,02716132 0,0710047 ! axis specification GO:0009798 7 7 0,000 0,02716132 0,07090413 ! negative regulation of muscle cell differentiation GO:0051148 7 7 0,000 0,02716132 0,07080384 ! visual behavior GO:0007632 7 7 0,000 0,02716132 0,07070384 GO:0008542|visual learning, ! startle response GO:0001964 7 7 0,000 0,02716132 0,07060411 ! amyloid precursor protein metabolic process GO:0042982 7 7 0,000 0,02716132 0,07050467 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 8 7 0,000 0,02716132 0,07040551 ! positive regulation of lipid metabolic process GO:0045834 7 7 0,000 0,02716132 0,07030662 ! negative regulation of lipid metabolic process GO:0045833 7 7 0,000 0,02716132 0,07020802 ! regulation of interferon-gamma biosynthetic process GO:0045072 7 7 0,000 0,02716132 0,07010969 ! endothelial cell differentiation GO:0045446 7 7 0,000 0,02716132 0,07001163 ! negative regulation of striated muscle development GO:0045843 7 7 0,000 0,02716132 0,06991385 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 7 7 0,000 0,02716132 0,06981634 ! digestive system development GO:0055123 7 7 0,000 0,02716132 0,0697191 GO:0048546|digestive tract morphogenesis, GO:0048547|gut morphogenesis, ! hemoglobin metabolic process GO:0020027 7 7 0,000 0,02716132 0,06962214 ! regulation of exit from mitosis GO:0007096 7 7 0,000 0,02716132 0,06952544 ! protein targeting to ER GO:0045047 8 7 0,000 0,02716132 0,06942901 ! cell differentiation in spinal cord GO:0021515 7 7 0,000 0,02716132 0,06933285 ! endoderm development GO:0007492 7 7 0,000 0,02716132 0,06923695 ! regulation of defense response to virus GO:0050688 7 7 0,000 0,02716132 0,06914132 ! glycolipid biosynthetic process GO:0009247 7 7 0,000 0,02716132 0,06904595 GO:0006688|glycosphingolipid biosynthetic process, ! regulation of mRNA processing GO:0050684 7 7 0,000 0,02716132 0,06895085 ! response to hexose stimulus GO:0009746 7 7 0,000 0,02716132 0,06885601 GO:0034284|response to monosaccharide stimulus, GO:0009749|response to glucose stimulus, ! membrane protein ectodomain proteolysis GO:0006509 7 7 0,000 0,02716132 0,06876142 GO:0033619|membrane protein proteolysis, ! positive regulation of survival gene product expression GO:0045885 7 7 0,000 0,02716132 0,0686671 ! regulation of skeletal muscle fiber development GO:0048742 7 7 0,000 0,02716132 0,06857304 ! nucleotide-sugar metabolic process GO:0009225 7 7 0,000 0,02716132 0,06847923 ! complement activation, alternative pathway GO:0006957 7 7 0,000 0,02716132 0,06838568 ! arachidonic acid secretion GO:0050482 7 7 0,000 0,02716132 0,06829238 GO:0032309|icosanoid secretion, ! polyamine biosynthetic process GO:0006596 7 7 0,000 0,02716132 0,06819934 ! UV protection GO:0009650 7 7 0,000 0,02716132 0,06810655 ! DNA integration GO:0015074 7 7 0,000 0,02716132 0,06801402 ! myofibril assembly GO:0030239 7 7 0,000 0,02716132 0,06792173 GO:0055002|striated muscle cell development, ! positive regulation of muscle contraction GO:0045933 7 7 0,000 0,02716132 0,0678297 ! negative regulation of muscle contraction GO:0045932 7 7 0,000 0,02716132 0,06773791 ! chondroitin sulfate biosynthetic process GO:0030206 7 7 0,000 0,02716132 0,06764637 GO:0030204|chondroitin sulfate metabolic process, ! regulation of exocytosis GO:0017157 8 7 0,000 0,02716132 0,06755508 ! phosphatidylcholine biosynthetic process GO:0006656 7 7 0,000 0,02716132 0,06746404 ! heparan sulfate proteoglycan metabolic process GO:0030201 7 7 0,000 0,02716132 0,06737324 GO:0015012|heparan sulfate proteoglycan biosynthetic process, ! stem cell development GO:0048864 7 7 0,000 0,02716132 0,06728268 GO:0019827|stem cell maintenance, ! alpha-beta T cell differentiation GO:0046632 7 7 0,000 0,02716132 0,06719237 ! negative regulation of myeloid leukocyte differentiation GO:0002762 7 7 0,000 0,02716132 0,0671023 ! NLS-bearing substrate import into nucleus GO:0006607 7 7 0,000 0,02716132 0,06701247 ! axon cargo transport GO:0008088 7 7 0,000 0,02716132 0,06692288 ! eating behavior GO:0042755 7 7 0,000 0,02716132 0,06683353 ! RNA-dependent DNA replication GO:0006278 7 7 0,000 0,02716132 0,06674442 ! purine nucleoside triphosphate catabolic process GO:0009146 7 7 0,000 0,02716132 0,06665555 ! regulation of interleukin-8 production GO:0032677 7 7 0,000 0,02716132 0,06656691 ! purine ribonucleotide catabolic process GO:0009154 7 7 0,000 0,02716132 0,06647851 ! ribosomal small subunit biogenesis GO:0042274 7 7 0,000 0,02716132 0,06639034 ! cranial nerve development GO:0021545 7 7 0,000 0,02716132 0,06630241 ! protein import into peroxisome matrix GO:0016558 7 7 0,000 0,02716132 0,0662147 ! induction of an organ GO:0001759 7 7 0,000 0,02716132 0,06612723 ! leukocyte activation during immune response GO:0002366 7 7 0,000 0,02716132 0,06603999 GO:0002263|cell activation during immune response, ! response to estradiol stimulus GO:0032355 7 7 0,000 0,02716132 0,06595299 ! autonomic nervous system development GO:0048483 7 7 0,000 0,02716132 0,06586621 ! intracellular lipid transport GO:0032365 7 7 0,000 0,02716132 0,06577965 ! detection of chemical stimulus GO:0009593 8 7 0,000 0,02716132 0,06569333 ! platelet activation GO:0030168 8 7 0,000 0,02716132 0,06560723 ! negative regulation of cytokine secretion GO:0050710 7 7 0,000 0,02716132 0,06552136 ! regulation of interleukin-1 secretion GO:0050704 7 7 0,000 0,02716132 0,06543571 ! natural killer cell activation GO:0030101 7 7 0,000 0,02716132 0,06535028 ! NADP metabolic process GO:0006739 7 7 0,000 0,02716132 0,06526508 ! neuromuscular synaptic transmission GO:0007274 7 7 0,000 0,02716132 0,0651801 ! synaptic transmission, cholinergic GO:0007271 7 7 0,000 0,02716132 0,06509534 ! ubiquinone metabolic process GO:0006743 7 7 0,000 0,02716132 0,0650108 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, GO:0042375|quinone cofactor metabolic process, ! regulation of macrophage differentiation GO:0045649 8 7 0,000 0,02716132 0,06492648 ! positive regulation of acute inflammatory response GO:0002675 7 7 0,000 0,02716132 0,06484238 ! regulation of osteoclast differentiation GO:0045670 7 7 0,000 0,02716132 0,06475849 ! multicellular organismal water homeostasis GO:0050891 7 7 0,000 0,02716132 0,06467483 ! regulation of ATPase activity GO:0043462 7 7 0,000 0,02716132 0,06459138 ! cell-cell recognition GO:0009988 8 7 0,000 0,02716132 0,06450814 ! hormone catabolic process GO:0042447 7 7 0,000 0,02716132 0,06442512 ! dopamine metabolic process GO:0042417 7 7 0,000 0,02716132 0,06434231 ! cAMP biosynthetic process GO:0006171 7 7 0,000 0,02716132 0,06425971 ! oxygen transport GO:0015671 7 7 0,000 0,02716132 0,06417733 ! pyridine nucleotide biosynthetic process GO:0019363 7 7 0,000 0,02716132 0,06409515 ! biogenic amine catabolic process GO:0042402 7 7 0,000 0,02716132 0,06401319 ! regulation of axon extension GO:0030516 7 7 0,000 0,02716132 0,06393144 ! cell killing GO:0001906 7 7 0,000 0,02716132 0,06384989 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 7 7 0,000 0,02716132 0,06376856 ! adult feeding behavior GO:0008343 7 7 0,000 0,02716132 0,06368742 ! pyrimidine nucleotide catabolic process GO:0006244 7 7 0,000 0,02716132 0,0636065 ! positive regulation of protein polymerization GO:0032273 7 7 0,000 0,02716132 0,06352578 ! T cell receptor signaling pathway GO:0050852 7 7 0,000 0,02716132 0,06344527 ! response to cold GO:0009409 7 7 0,000 0,02716132 0,06336496 ! cell morphogenesis involved in neuron differentiation GO:0048667 72 67 1,000 0,02803915 0,06533016 GO:0048812|neuron projection morphogenesis, GO:0048858|cell projection morphogenesis, ! negative regulation of cell differentiation GO:0045596 68 67 1,000 0,02803915 0,06524767 ! Ras protein signal transduction GO:0007265 69 67 1,000 0,02803915 0,06516539 ! regulation of cell size GO:0008361 68 68 1,000 0,02881975 0,0668952 ! regionalization GO:0003002 70 69 1,000 0,02960908 0,06864093 ! response to nutrient levels GO:0031667 69 69 1,000 0,02960908 0,0685547 ! regulation of leukocyte activation GO:0002694 69 69 1,000 0,02960908 0,06846869 ! regulation of mitotic cell cycle GO:0007346 72 69 1,000 0,02960908 0,06838289 ! positive regulation of transport GO:0051050 71 70 1,000 0,03040709 0,07013801 ! cell part morphogenesis GO:0032990 75 70 1,000 0,03040709 0,07005034 ! growth GO:0040007 70 70 1,000 0,03040709 0,06996288 ! regulation of skeletal muscle tissue development GO:0048641 8 8 0,000 0,03098304 0,07119917 ! negative regulation of muscle development GO:0048635 8 8 0,000 0,03098304 0,07111051 ! very-long-chain fatty acid metabolic process GO:0000038 8 8 0,000 0,03098304 0,07102206 ! positive regulation of translation GO:0045727 8 8 0,000 0,03098304 0,07093383 ! positive regulation of cell killing GO:0031343 8 8 0,000 0,03098304 0,07084583 ! superoxide anion generation GO:0042554 8 8 0,000 0,03098304 0,07075804 ! sulfur amino acid biosynthetic process GO:0000097 8 8 0,000 0,03098304 0,07067047 ! cGMP metabolic process GO:0046068 8 8 0,000 0,03098304 0,07058311 GO:0006182|cGMP biosynthetic process, ! thyroid gland development GO:0030878 8 8 0,000 0,03098304 0,07049597 ! 'de novo' protein folding GO:0006458 8 8 0,000 0,03098304 0,07040905 ! dicarboxylic acid transport GO:0006835 8 8 0,000 0,03098304 0,07032233 ! phosphoinositide phosphorylation GO:0046854 8 8 0,000 0,03098304 0,07023584 ! embryonic hindlimb morphogenesis GO:0035116 8 8 0,000 0,03098304 0,07014955 ! zinc ion transport GO:0006829 8 8 0,000 0,03098304 0,07006348 ! embryonic forelimb morphogenesis GO:0035115 8 8 0,000 0,03098304 0,06997762 ! folic acid and derivative biosynthetic process GO:0009396 8 8 0,000 0,03098304 0,06989197 ! regulation of neuronal synaptic plasticity GO:0048168 8 8 0,000 0,03098304 0,06980652 ! cardiac muscle contraction GO:0060048 8 8 0,000 0,03098304 0,06972129 ! lipid localization GO:0010876 8 8 0,000 0,03098304 0,06963626 GO:0019915|lipid storage, ! response to pain GO:0048265 8 8 0,000 0,03098304 0,06955144 ! response to cAMP GO:0051591 8 8 0,000 0,03098304 0,06946683 ! COPI coating of Golgi vesicle GO:0048205 8 8 0,000 0,03098304 0,06938243 GO:0048200|Golgi transport vesicle coating, ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 8 0,000 0,03098304 0,06929822 ! negative regulation of transcription factor import into nucleus GO:0042992 8 8 0,000 0,03098304 0,06921423 ! negative regulation of ion transport GO:0043271 8 8 0,000 0,03098304 0,06913043 ! regulation of response to extracellular stimulus GO:0032104 8 8 0,000 0,03098304 0,06904684 GO:0032107|regulation of response to nutrient levels, ! adult walking behavior GO:0007628 8 8 0,000 0,03098304 0,06896345 ! sensory perception of taste GO:0050909 8 8 0,000 0,03098304 0,06888026 ! organelle fusion GO:0048284 8 8 0,000 0,03098304 0,06879727 ! pancreas development GO:0031016 8 8 0,000 0,03098304 0,06871448 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 8 8 0,000 0,03098304 0,06863189 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! T cell selection GO:0045058 8 8 0,000 0,03098304 0,0685495 ! negative regulation of proteolysis GO:0045861 8 8 0,000 0,03098304 0,06846731 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 8 8 0,000 0,03098304 0,06838531 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 8 8 0,000 0,03098304 0,06830351 ! sperm motility GO:0030317 8 8 0,000 0,03098304 0,06822191 ! regulation of striated muscle contraction GO:0006942 8 8 0,000 0,03098304 0,0681405 ! DNA duplex unwinding GO:0032508 8 8 0,000 0,03098304 0,06805928 GO:0032392|DNA geometric change, ! glycine metabolic process GO:0006544 8 8 0,000 0,03098304 0,06797826 ! ribonucleotide catabolic process GO:0009261 8 8 0,000 0,03098304 0,06789743 ! negative regulation of microtubule depolymerization GO:0007026 8 8 0,000 0,03098304 0,06781679 GO:0031114|regulation of microtubule depolymerization, ! phosphagen metabolic process GO:0006599 8 8 0,000 0,03098304 0,06773634 GO:0006600|creatine metabolic process, ! polyamine metabolic process GO:0006595 8 8 0,000 0,03098304 0,06765609 ! Golgi organization GO:0007030 8 8 0,000 0,03098304 0,06757602 ! cell-cell junction assembly GO:0007043 8 8 0,000 0,03098304 0,06749614 ! regulation of stress fiber formation GO:0051492 9 8 0,000 0,03098304 0,06741645 ! fructose metabolic process GO:0006000 8 8 0,000 0,03098304 0,06733695 ! mannose metabolic process GO:0006013 9 8 0,000 0,03098304 0,06725764 ! NAD metabolic process GO:0019674 8 8 0,000 0,03098304 0,06717851 ! negative regulation of mitotic cell cycle GO:0045930 9 8 0,000 0,03098304 0,06709957 ! plasma membrane fusion GO:0045026 8 8 0,000 0,03098304 0,06702082 ! response to fungus GO:0009620 8 8 0,000 0,03098304 0,06694225 ! stem cell differentiation GO:0048863 8 8 0,000 0,03098304 0,06686386 ! alpha-beta T cell activation GO:0046631 8 8 0,000 0,03098304 0,06678566 ! positive regulation of myeloid leukocyte differentiation GO:0002763 9 8 0,000 0,03098304 0,06670764 ! embryonic digit morphogenesis GO:0042733 8 8 0,000 0,03098304 0,0666298 ! regulation of cytokine production during immune response GO:0002718 8 8 0,000 0,03098304 0,06655214 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 0,03098304 0,06647466 ! regulation of vasodilation GO:0042312 8 8 0,000 0,03098304 0,06639737 ! vasoconstriction GO:0042310 8 8 0,000 0,03098304 0,06632025 ! regulation of T cell mediated immunity GO:0002709 8 8 0,000 0,03098304 0,06624331 ! muscle cell development GO:0055001 8 8 0,000 0,03098304 0,06616655 ! nucleoside triphosphate catabolic process GO:0009143 8 8 0,000 0,03098304 0,06608997 ! regulation of fatty acid metabolic process GO:0019217 8 8 0,000 0,03098304 0,06601357 ! sensory perception of pain GO:0019233 8 8 0,000 0,03098304 0,06593734 ! gastrulation with mouth forming second GO:0001702 8 8 0,000 0,03098304 0,06586129 ! immunoglobulin production during immune response GO:0002381 8 8 0,000 0,03098304 0,06578541 GO:0002208|somatic diversification of immunoglobulins during immune response, GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! mRNA cleavage GO:0006379 8 8 0,000 0,03098304 0,06570971 ! chromatin silencing GO:0006342 8 8 0,000 0,03098304 0,06563418 ! tissue regeneration GO:0042246 8 8 0,000 0,03098304 0,06555882 ! salivary gland development GO:0007431 8 8 0,000 0,03098304 0,06548364 ! negative regulation of blood coagulation GO:0030195 9 8 0,000 0,03098304 0,06540863 ! T cell homeostasis GO:0043029 8 8 0,000 0,03098304 0,06533379 ! peptide biosynthetic process GO:0043043 9 8 0,000 0,03098304 0,06525913 ! peptidyl-serine modification GO:0018209 8 8 0,000 0,03098304 0,06518463 ! water homeostasis GO:0030104 8 8 0,000 0,03098304 0,0651103 ! cofactor transport GO:0051181 8 8 0,000 0,03098304 0,06503615 ! regulation of acute inflammatory response GO:0002673 8 8 0,000 0,03098304 0,06496216 ! acid secretion GO:0046717 8 8 0,000 0,03098304 0,06488834 ! C21-steroid hormone biosynthetic process GO:0006700 8 8 0,000 0,03098304 0,06481468 ! protein-chromophore linkage GO:0018298 9 8 0,000 0,03098304 0,0647412 ! regulation of immunoglobulin production GO:0002637 8 8 0,000 0,03098304 0,06466788 ! branched chain family amino acid metabolic process GO:0009081 8 8 0,000 0,03098304 0,06459472 ! catecholamine biosynthetic process GO:0042423 8 8 0,000 0,03098304 0,06452174 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 8 8 0,000 0,03098304 0,06444891 ! aromatic compound biosynthetic process GO:0019438 8 8 0,000 0,03098304 0,06437625 ! regulation of organic acid transport GO:0032890 8 8 0,000 0,03098304 0,06430376 ! positive regulation of calcium ion transport GO:0051928 8 8 0,000 0,03098304 0,06423142 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 8 8 0,000 0,03098304 0,06415925 ! regulation of multi-organism process GO:0043900 8 8 0,000 0,03098304 0,06408725 ! positive regulation of amine transport GO:0051954 8 8 0,000 0,03098304 0,0640154 ! developmental induction GO:0031128 8 8 0,000 0,03098304 0,06394371 GO:0045168|cell-cell signaling involved in cell fate specification, ! peptide hormone secretion GO:0030072 8 8 0,000 0,03098304 0,06387219 ! positive regulation of calcium-mediated signaling GO:0050850 8 8 0,000 0,03098304 0,06380082 ! actin filament polymerization GO:0030041 9 8 0,000 0,03098304 0,06372962 ! cytoplasmic sequestering of protein GO:0051220 8 8 0,000 0,03098304 0,06365857 ! peptide hormone processing GO:0016486 8 8 0,000 0,03098304 0,06358768 ! positive regulation of synaptic transmission GO:0050806 8 8 0,000 0,03098304 0,06351695 ! regulation of steroid biosynthetic process GO:0050810 8 8 0,000 0,03098304 0,06344637 ! translational elongation GO:0006414 71 71 1,000 0,03121369 0,06384776 ! negative regulation of signal transduction GO:0009968 71 71 1,000 0,03121369 0,06377698 ! regulation of cell activation GO:0050865 71 71 1,000 0,03121369 0,06370635 ! secretion by cell GO:0032940 75 72 1,000 0,03202881 0,06529767 ! response to extracellular stimulus GO:0009991 72 72 1,000 0,03202881 0,06522552 ! lactation GO:0007595 10 9 0,000 0,03479029 0,07077098 ! embryonic pattern specification GO:0009880 10 9 0,000 0,03479029 0,07069295 ! positive regulation of cell size GO:0045793 9 9 0,000 0,03479029 0,0706151 ! regulation of membrane protein ectodomain proteolysis GO:0051043 9 9 0,000 0,03479029 0,07053741 ! positive regulation of protein complex assembly GO:0031334 9 9 0,000 0,03479029 0,0704599 ! cortical actin cytoskeleton organization GO:0030866 10 9 0,000 0,03479029 0,07038255 ! negative regulation of cell cycle process GO:0010948 9 9 0,000 0,03479029 0,07030538 ! viral genome replication GO:0019079 9 9 0,000 0,03479029 0,07022838 ! phospholipid catabolic process GO:0009395 9 9 0,000 0,03479029 0,07015154 ! copper ion transport GO:0006825 9 9 0,000 0,03479029 0,07007487 ! lipid phosphorylation GO:0046834 9 9 0,000 0,03479029 0,06999837 ! aminoglycan catabolic process GO:0006026 9 9 0,000 0,03479029 0,06992204 ! Golgi vesicle budding GO:0048194 9 9 0,000 0,03479029 0,06984587 ! regulation of cell-cell adhesion GO:0022407 9 9 0,000 0,03479029 0,06976987 ! RNA polyadenylation GO:0043631 9 9 0,000 0,03479029 0,06969403 GO:0006378|mRNA polyadenylation, ! gamma-aminobutyric acid signaling pathway GO:0007214 9 9 0,000 0,03479029 0,06961836 ! regulation of postsynaptic membrane potential GO:0060078 9 9 0,000 0,03479029 0,06954285 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 9 9 0,000 0,03479029 0,06946751 ! negative regulation of cytokine biosynthetic process GO:0042036 9 9 0,000 0,03479029 0,06939232 ! phospholipid efflux GO:0033700 9 9 0,000 0,03479029 0,06931731 ! response to alkaloid GO:0043279 10 9 0,000 0,03479029 0,06924245 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 9 9 0,000 0,03479029 0,06916775 ! cytokine biosynthetic process GO:0042089 9 9 0,000 0,03479029 0,06909322 GO:0042107|cytokine metabolic process, ! negative regulation of gene expression, epigenetic GO:0045814 9 9 0,000 0,03479029 0,06901885 ! regulation of interleukin-2 biosynthetic process GO:0045076 9 9 0,000 0,03479029 0,06894463 ! response to ethanol GO:0045471 9 9 0,000 0,03479029 0,06887058 ! pyrimidine ribonucleotide metabolic process GO:0009218 9 9 0,000 0,03479029 0,06879668 ! activation of pro-apoptotic gene products GO:0008633 9 9 0,000 0,03479029 0,06872294 ! methionine metabolic process GO:0006555 9 9 0,000 0,03479029 0,06864937 ! glutamine metabolic process GO:0006541 9 9 0,000 0,03479029 0,06857594 ! cerebral cortex development GO:0021987 9 9 0,000 0,03479029 0,06850268 ! response to osmotic stress GO:0006970 9 9 0,000 0,03479029 0,06842957 ! pigmentation during development GO:0048066 9 9 0,000 0,03479029 0,06835662 ! reverse cholesterol transport GO:0043691 9 9 0,000 0,03479029 0,06828382 ! central nervous system neuron development GO:0021954 10 9 0,000 0,03479029 0,06821118 ! pyrimidine ribonucleoside metabolic process GO:0046131 9 9 0,000 0,03479029 0,06813869 ! nucleobase biosynthetic process GO:0046112 9 9 0,000 0,03479029 0,06806636 ! neurotransmitter metabolic process GO:0042133 11 9 0,000 0,03479029 0,06799418 ! negative regulation of caspase activity GO:0043154 9 9 0,000 0,03479029 0,06792215 ! branching involved in ureteric bud morphogenesis GO:0001658 9 9 0,000 0,03479029 0,06785027 GO:0060675|ureteric bud morphogenesis, ! L-glutamate transport GO:0015813 9 9 0,000 0,03479029 0,06777855 GO:0015800|acidic amino acid transport, ! peptide secretion GO:0002790 9 9 0,000 0,03479029 0,06770698 ! regulation of dephosphorylation GO:0035303 9 9 0,000 0,03479029 0,06763556 ! cotranslational protein targeting to membrane GO:0006613 10 9 0,000 0,03479029 0,06756429 ! positive regulation of alpha-beta T cell differentiation GO:0046638 9 9 0,000 0,03479029 0,06749317 ! ventricular cardiac muscle morphogenesis GO:0055010 9 9 0,000 0,03479029 0,06742219 ! behavioral interaction between organisms GO:0051705 9 9 0,000 0,03479029 0,06735137 ! negative regulation of protein import into nucleus GO:0042308 9 9 0,000 0,03479029 0,0672807 ! DNA replication initiation GO:0006270 9 9 0,000 0,03479029 0,06721018 ! prostaglandin metabolic process GO:0006693 9 9 0,000 0,03479029 0,0671398 GO:0006692|prostanoid metabolic process, ! T cell differentiation in the thymus GO:0033077 9 9 0,000 0,03479029 0,06706957 ! DNA fragmentation involved in apoptosis GO:0006309 9 9 0,000 0,03479029 0,06699949 ! regulation of immunoglobulin mediated immune response GO:0002889 9 9 0,000 0,03479029 0,06692955 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 10 9 0,000 0,03479029 0,06685976 ! positive regulation of oxidoreductase activity GO:0051353 9 9 0,000 0,03479029 0,06679011 ! positive regulation of cytokine secretion GO:0050715 9 9 0,000 0,03479029 0,06672061 ! negative regulation of inflammatory response GO:0050728 9 9 0,000 0,03479029 0,06665125 ! negative regulation of protein secretion GO:0050709 9 9 0,000 0,03479029 0,06658204 ! positive regulation of transmission of nerve impulse GO:0051971 9 9 0,000 0,03479029 0,06651297 ! collagen catabolic process GO:0030574 9 9 0,000 0,03479029 0,06644405 ! aromatic amino acid family catabolic process GO:0009074 9 9 0,000 0,03479029 0,06637527 ! purine base metabolic process GO:0006144 9 9 0,000 0,03479029 0,06630663 ! gas transport GO:0015669 9 9 0,000 0,03479029 0,06623813 ! cholesterol efflux GO:0033344 9 9 0,000 0,03479029 0,06616977 ! regulation of leukocyte mediated cytotoxicity GO:0001910 9 9 0,000 0,03479029 0,06610155 ! estrogen receptor signaling pathway GO:0030520 9 9 0,000 0,03479029 0,06603348 ! somatic recombination of immunoglobulin gene segments GO:0016447 9 9 0,000 0,03479029 0,06596554 ! regulation of actin filament bundle formation GO:0032231 10 9 0,000 0,03479029 0,06589775 ! defense response to virus GO:0051607 9 9 0,000 0,03479029 0,06583009 ! regulation of calcium-mediated signaling GO:0050848 9 9 0,000 0,03479029 0,06576257 ! actin filament-based movement GO:0030048 9 9 0,000 0,03479029 0,06569519 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 9 9 0,000 0,03479029 0,06562795 ! negative regulation of cell communication GO:0010648 76 76 1,000 0,035373 0,06665894 ! regulation of protein modification process GO:0031399 79 78 1,000 0,03709431 0,06983128 ! positive regulation of protein kinase cascade GO:0010740 79 78 1,000 0,03709431 0,06976002 ! nuclear transport GO:0051169 79 79 1,000 0,03796702 0,07132846 GO:0006913|nucleocytoplasmic transport, ! protein import into nucleus, docking GO:0000059 10 10 0,000 0,03858314 0,07241215 ! regulation of protein ubiquitination GO:0031396 10 10 0,000 0,03858314 0,07233848 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 10 10 0,000 0,03858314 0,07226497 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 10 10 0,000 0,03858314 0,0721916 ! ER-associated protein catabolic process GO:0030433 10 10 0,000 0,03858314 0,07211838 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of cell killing GO:0031341 10 10 0,000 0,03858314 0,07204532 ! neuron maturation GO:0042551 10 10 0,000 0,03858314 0,0719724 ! pteridine and derivative metabolic process GO:0042558 10 10 0,000 0,03858314 0,07189962 ! positive regulation of anti-apoptosis GO:0045768 10 10 0,000 0,03858314 0,071827 GO:0045767|regulation of anti-apoptosis, ! cortical cytoskeleton organization GO:0030865 11 10 0,000 0,03858314 0,07175452 ! regulation of lipid biosynthetic process GO:0046890 10 10 0,000 0,03858314 0,07168218 ! reciprocal meiotic recombination GO:0007131 10 10 0,000 0,03858314 0,07161 ! hormone secretion GO:0046879 10 10 0,000 0,03858314 0,07153795 ! glucosamine metabolic process GO:0006041 10 10 0,000 0,03858314 0,07146606 GO:0006044|N-acetylglucosamine metabolic process, ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 10 10 0,000 0,03858314 0,0713943 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! negative regulation of nucleocytoplasmic transport GO:0046823 10 10 0,000 0,03858314 0,0713227 ! cAMP metabolic process GO:0046058 10 10 0,000 0,03858314 0,07125123 ! vesicle targeting, to, from or within Golgi GO:0048199 10 10 0,000 0,03858314 0,07117991 ! transcription from RNA polymerase III promoter GO:0006383 10 10 0,000 0,03858314 0,07110873 ! forelimb morphogenesis GO:0035136 10 10 0,000 0,03858314 0,07103769 ! glial cell development GO:0021782 10 10 0,000 0,03858314 0,07096679 ! phototransduction GO:0007602 11 10 0,000 0,03858314 0,07089604 ! calcium-independent cell-cell adhesion GO:0016338 10 10 0,000 0,03858314 0,07082543 ! auditory receptor cell differentiation GO:0042491 10 10 0,000 0,03858314 0,07075495 ! fat cell differentiation GO:0045444 10 10 0,000 0,03858314 0,07068462 ! myoblast differentiation GO:0045445 10 10 0,000 0,03858314 0,07061443 ! inactivation of MAPK activity GO:0000188 10 10 0,000 0,03858314 0,07054437 ! positive regulation of proteolysis GO:0045862 10 10 0,000 0,03858314 0,07047446 ! response to carbohydrate stimulus GO:0009743 10 10 0,000 0,03858314 0,07040468 ! regulation of survival gene product expression GO:0045884 10 10 0,000 0,03858314 0,07033504 ! induction of apoptosis via death domain receptors GO:0008625 10 10 0,000 0,03858314 0,07026554 ! epidermis morphogenesis GO:0048730 10 10 0,000 0,03858314 0,07019618 ! protein polyubiquitination GO:0000209 10 10 0,000 0,03858314 0,07012695 ! glutamate metabolic process GO:0006536 11 10 0,000 0,03858314 0,07005786 ! plasma membrane organization GO:0007009 10 10 0,000 0,03858314 0,0699889 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 10 10 0,000 0,03858314 0,06992009 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cell-substrate junction assembly GO:0007044 11 10 0,000 0,03858314 0,0698514 ! lysosomal transport GO:0007041 10 10 0,000 0,03858314 0,06978285 ! cellular response to unfolded protein GO:0034620 10 10 0,000 0,03858314 0,06971444 GO:0030968|endoplasmic reticulum unfolded protein response, ! central nervous system neuron differentiation GO:0021953 11 10 0,000 0,03858314 0,06964616 ! purine ribonucleoside metabolic process GO:0046128 10 10 0,000 0,03858314 0,06957801 GO:0042278|purine nucleoside metabolic process, ! vesicle coating GO:0006901 10 10 0,000 0,03858314 0,06951 ! exocrine system development GO:0035272 10 10 0,000 0,03858314 0,06944212 ! cell structure disassembly during apoptosis GO:0006921 10 10 0,000 0,03858314 0,06937437 ! regulation of protein binding GO:0043393 11 10 0,000 0,03858314 0,06930675 ! protein targeting to peroxisome GO:0006625 10 10 0,000 0,03858314 0,06923927 ! protein targeting to mitochondrion GO:0006626 10 10 0,000 0,03858314 0,06917191 GO:0070585|protein localization in mitochondrion, ! regulation of alpha-beta T cell differentiation GO:0046637 10 10 0,000 0,03858314 0,06910469 ! intermediate filament cytoskeleton organization GO:0045104 10 10 0,000 0,03858314 0,0690376 ! protein export from nucleus GO:0006611 10 10 0,000 0,03858314 0,06897064 ! negative regulation of immune response GO:0050777 10 10 0,000 0,03858314 0,06890381 ! cytolysis GO:0019835 10 10 0,000 0,03858314 0,0688371 ! positive regulation of biomineral formation GO:0070169 10 10 0,000 0,03858314 0,06877053 GO:0030501|positive regulation of bone mineralization, ! mismatch repair GO:0006298 10 10 0,000 0,03858314 0,06870408 ! regulation of B cell differentiation GO:0045577 10 10 0,000 0,03858314 0,06863777 ! histone deacetylation GO:0016575 10 10 0,000 0,03858314 0,06857158 ! mRNA splice site selection GO:0006376 11 10 0,000 0,03858314 0,06850552 ! synaptic vesicle transport GO:0048489 11 10 0,000 0,03858314 0,06843958 ! gland morphogenesis GO:0022612 10 10 0,000 0,03858314 0,06837378 ! positive regulation of neurological system process GO:0031646 10 10 0,000 0,03858314 0,0683081 ! sphingolipid biosynthetic process GO:0030148 10 10 0,000 0,03858314 0,06824254 GO:0046467|membrane lipid biosynthetic process, ! sphingolipid catabolic process GO:0030149 10 10 0,000 0,03858314 0,06817711 GO:0046466|membrane lipid catabolic process, ! nerve-nerve synaptic transmission GO:0007270 10 10 0,000 0,03858314 0,06811181 ! regulation of erythrocyte differentiation GO:0045646 10 10 0,000 0,03858314 0,06804663 ! regulation of epidermis development GO:0045682 10 10 0,000 0,03858314 0,06798157 ! folic acid and derivative metabolic process GO:0006760 10 10 0,000 0,03858314 0,06791664 ! negative regulation of neuron differentiation GO:0045665 10 10 0,000 0,03858314 0,06785184 ! aspartate family amino acid biosynthetic process GO:0009067 10 10 0,000 0,03858314 0,06778716 ! regulation of BMP signaling pathway GO:0030510 10 10 0,000 0,03858314 0,0677226 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 10 10 0,000 0,03858314 0,06765816 ! lymphocyte homeostasis GO:0002260 10 10 0,000 0,03858314 0,06759385 ! nerve development GO:0021675 10 10 0,000 0,03858314 0,06752966 ! gut development GO:0048565 10 10 0,000 0,03858314 0,06746559 ! embryonic organ morphogenesis GO:0048562 10 10 0,000 0,03858314 0,06740164 ! mRNA 3'-end processing GO:0031124 10 10 0,000 0,03858314 0,06733781 ! antigen receptor-mediated signaling pathway GO:0050851 10 10 0,000 0,03858314 0,0672741 ! negative regulation of coagulation GO:0050819 11 10 0,000 0,03858314 0,06721052 ! protein stabilization GO:0050821 10 10 0,000 0,03858314 0,06714705 ! lymphocyte activation GO:0046649 82 81 1,000 0,03973618 0,06908847 ! lipid catabolic process GO:0016042 82 81 1,000 0,03973618 0,06902335 ! protein secretion GO:0009306 11 11 0,000 0,04236163 0,07351459 ! oligosaccharide metabolic process GO:0009311 11 11 0,000 0,04236163 0,07344543 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 11 11 0,000 0,04236163 0,0733764 ! myeloid leukocyte differentiation GO:0002573 12 11 0,000 0,04236163 0,0733075 ! negative regulation of defense response GO:0031348 11 11 0,000 0,04236163 0,07323874 ! G1 phase of mitotic cell cycle GO:0000080 12 11 0,000 0,04236163 0,0731701 ! determination of bilateral symmetry GO:0009855 11 11 0,000 0,04236163 0,07310158 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! positive regulation of hormone secretion GO:0046887 11 11 0,000 0,04236163 0,0730332 ! phosphatidylinositol metabolic process GO:0046488 11 11 0,000 0,04236163 0,07296495 ! skin development GO:0043588 11 11 0,000 0,04236163 0,07289682 ! cellular component assembly involved in morphogenesis GO:0010927 11 11 0,000 0,04236163 0,07282882 ! signal complex assembly GO:0007172 11 11 0,000 0,04236163 0,07276094 ! microtubule-based transport GO:0010970 11 11 0,000 0,04236163 0,0726932 ! peroxisomal transport GO:0043574 11 11 0,000 0,04236163 0,07262557 ! protein amino acid methylation GO:0006479 11 11 0,000 0,04236163 0,07255808 GO:0008213|protein amino acid alkylation, ! heart contraction GO:0060047 11 11 0,000 0,04236163 0,07249071 GO:0003015|heart process, ! detection of light stimulus involved in sensory perception GO:0050962 12 11 0,000 0,04236163 0,07242346 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 11 11 0,000 0,04236163 0,07235634 ! T cell proliferation GO:0042098 11 11 0,000 0,04236163 0,07228934 ! regulation of transmembrane transporter activity GO:0022898 11 11 0,000 0,04236163 0,07222247 GO:0032412|regulation of ion transmembrane transporter activity, GO:0032409|regulation of transporter activity, ! negative regulation of endothelial cell proliferation GO:0001937 11 11 0,000 0,04236163 0,07215572 ! regulation of viral genome replication GO:0045069 11 11 0,000 0,04236163 0,0720891 ! spinal cord development GO:0021510 11 11 0,000 0,04236163 0,07202259 ! smooth muscle contraction GO:0006939 11 11 0,000 0,04236163 0,07195621 ! cellular macromolecular complex disassembly GO:0034623 12 11 0,000 0,04236163 0,07188996 ! digestive system process GO:0022600 11 11 0,000 0,04236163 0,07182382 ! mitotic spindle organization GO:0007052 11 11 0,000 0,04236163 0,07175781 ! fucose metabolic process GO:0006004 11 11 0,000 0,04236163 0,07169191 ! membrane budding GO:0006900 11 11 0,000 0,04236163 0,07162614 ! apoptotic nuclear changes GO:0030262 11 11 0,000 0,04236163 0,07156049 ! monoamine transport GO:0015844 11 11 0,000 0,04236163 0,07149496 ! regulation of cellular ketone metabolic process GO:0010565 11 11 0,000 0,04236163 0,07142954 ! response to lipopolysaccharide GO:0032496 11 11 0,000 0,04236163 0,07136425 ! body fluid secretion GO:0007589 11 11 0,000 0,04236163 0,07129908 ! positive regulation of alpha-beta T cell activation GO:0046635 11 11 0,000 0,04236163 0,07123403 ! intermediate filament-based process GO:0045103 11 11 0,000 0,04236163 0,07116909 ! cardiac muscle tissue morphogenesis GO:0055008 11 11 0,000 0,04236163 0,07110427 GO:0060415|muscle tissue morphogenesis, ! membrane depolarization GO:0051899 11 11 0,000 0,04236163 0,07103957 ! regulation of interleukin-2 production GO:0032663 11 11 0,000 0,04236163 0,07097499 ! regulation of ARF GTPase activity GO:0032312 11 11 0,000 0,04236163 0,07091053 ! oogenesis GO:0048477 11 11 0,000 0,04236163 0,07084618 ! negative regulation of angiogenesis GO:0016525 11 11 0,000 0,04236163 0,07078195 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 11 11 0,000 0,04236163 0,07071784 ! vitamin transport GO:0051180 11 11 0,000 0,04236163 0,07065384 ! muscle maintenance GO:0046716 12 11 0,000 0,04236163 0,07058996 ! hindbrain development GO:0030902 11 11 0,000 0,04236163 0,07052619 ! steroid catabolic process GO:0006706 11 11 0,000 0,04236163 0,07046254 ! endocrine process GO:0050886 11 11 0,000 0,04236163 0,070399 GO:0001990|regulation of systemic arterial blood pressure by hormone, ! aromatic amino acid family metabolic process GO:0009072 11 11 0,000 0,04236163 0,07033558 ! proximal/distal pattern formation GO:0009954 11 11 0,000 0,04236163 0,07027227 ! somatic diversification of immunoglobulins GO:0016445 11 11 0,000 0,04236163 0,07020908 ! RNA 3'-end processing GO:0031123 11 11 0,000 0,04236163 0,07014599 ! regulation of cellular localization GO:0060341 86 85 1,000 0,04336753 0,07174717 ! positive regulation of response to stimulus GO:0048584 86 85 1,000 0,04336753 0,07168282 ! organophosphate metabolic process GO:0019637 87 86 1,000 0,04429434 0,07314916 GO:0006644|phospholipid metabolic process, ! hexose metabolic process GO:0019318 87 86 1,000 0,04429434 0,07308367 ! positive regulation of protein catabolic process GO:0045732 12 12 0,000 0,04612583 0,07603748 ! translational initiation GO:0006413 12 12 0,000 0,04612583 0,07596952 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 12 12 0,000 0,04612583 0,07590169 ! positive regulation of angiogenesis GO:0045766 12 12 0,000 0,04612583 0,07583399 ! initiation of viral infection GO:0019059 12 12 0,000 0,04612583 0,0757664 ! DNA catabolic process, endonucleolytic GO:0000737 12 12 0,000 0,04612583 0,07569893 ! iron ion transport GO:0006826 13 12 0,000 0,04612583 0,07563158 ! phosphatidylcholine metabolic process GO:0046470 12 12 0,000 0,04612583 0,07556435 ! amino sugar metabolic process GO:0006040 12 12 0,000 0,04612583 0,07549725 ! post-Golgi vesicle-mediated transport GO:0006892 12 12 0,000 0,04612583 0,07543026 ! protein amino acid ADP-ribosylation GO:0006471 12 12 0,000 0,04612583 0,07536338 ! heterophilic cell adhesion GO:0007157 12 12 0,000 0,04612583 0,07529663 ! collagen metabolic process GO:0032963 12 12 0,000 0,04612583 0,07523 ! hindlimb morphogenesis GO:0035137 12 12 0,000 0,04612583 0,07516348 ! xenobiotic metabolic process GO:0006805 12 12 0,000 0,04612583 0,07509708 ! glutamate signaling pathway GO:0007215 12 12 0,000 0,04612583 0,0750308 ! C21-steroid hormone metabolic process GO:0008207 13 12 0,000 0,04612583 0,07496464 ! regulation of muscle cell differentiation GO:0051147 13 12 0,000 0,04612583 0,07489859 ! cellular response to hydrogen peroxide GO:0070301 12 12 0,000 0,04612583 0,07483266 GO:0042744|hydrogen peroxide catabolic process, ! negative regulation of peptidase activity GO:0010466 12 12 0,000 0,04612583 0,07476684 ! actomyosin structure organization GO:0031032 12 12 0,000 0,04612583 0,07470114 ! positive regulation of endocytosis GO:0045807 12 12 0,000 0,04612583 0,07463556 ! retinoid metabolic process GO:0001523 12 12 0,000 0,04612583 0,07457009 GO:0016101|diterpenoid metabolic process, ! mitotic chromosome condensation GO:0007076 12 12 0,000 0,04612583 0,07450473 ! positive regulation of innate immune response GO:0045089 12 12 0,000 0,04612583 0,07443949 ! GPI anchor biosynthetic process GO:0006506 12 12 0,000 0,04612583 0,07437436 GO:0006505|GPI anchor metabolic process, ! glycoprotein catabolic process GO:0006516 13 12 0,000 0,04612583 0,07430935 ! acute-phase response GO:0006953 12 12 0,000 0,04612583 0,07424445 ! deoxyribonucleotide catabolic process GO:0009264 12 12 0,000 0,04612583 0,07417967 ! vacuolar transport GO:0007034 12 12 0,000 0,04612583 0,07411499 ! polysaccharide catabolic process GO:0000272 12 12 0,000 0,04612583 0,07405043 ! vesicle docking during exocytosis GO:0006904 12 12 0,000 0,04612583 0,07398599 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 12 12 0,000 0,04612583 0,07392165 ! barbed-end actin filament capping GO:0051016 12 12 0,000 0,04612583 0,07385743 GO:0051693|actin filament capping, ! osteoblast differentiation GO:0001649 12 12 0,000 0,04612583 0,07379331 ! male gonad development GO:0008584 12 12 0,000 0,04612583 0,07372931 ! regulation of insulin secretion GO:0050796 12 12 0,000 0,04612583 0,07366542 ! regulation of alpha-beta T cell activation GO:0046634 12 12 0,000 0,04612583 0,07360164 ! renal system process GO:0003014 12 12 0,000 0,04612583 0,07353797 ! regulation of tumor necrosis factor production GO:0032680 12 12 0,000 0,04612583 0,07347441 ! regulation of steroid metabolic process GO:0019218 12 12 0,000 0,04612583 0,07341097 ! fibroblast growth factor receptor signaling pathway GO:0008543 12 12 0,000 0,04612583 0,07334763 ! regulation of interleukin-6 production GO:0032675 12 12 0,000 0,04612583 0,07328439 ! pallium development GO:0021543 13 12 0,000 0,04612583 0,07322127 ! cell fate determination GO:0001709 12 12 0,000 0,04612583 0,07315826 ! regulation of chromosome organization GO:0033044 12 12 0,000 0,04612583 0,07309536 ! positive regulation of multicellular organism growth GO:0040018 12 12 0,000 0,04612583 0,07303256 ! G1 phase GO:0051318 13 12 0,000 0,04612583 0,07296987 ! regulation of response to biotic stimulus GO:0002831 12 12 0,000 0,04612583 0,07290729 ! positive regulation of adaptive immune response GO:0002821 12 12 0,000 0,04612583 0,07284481 ! detection of light stimulus GO:0009583 13 12 0,000 0,04612583 0,07278245 ! synaptogenesis GO:0007416 12 12 0,000 0,04612583 0,07272019 ! hormone transport GO:0009914 12 12 0,000 0,04612583 0,07265803 ! neurotransmitter secretion GO:0007269 14 12 0,000 0,04612583 0,07259598 ! heme biosynthetic process GO:0006783 12 12 0,000 0,04612583 0,07253404 ! spermatid differentiation GO:0048515 13 12 0,000 0,04612583 0,07247221 GO:0007286|spermatid development, ! aromatic compound catabolic process GO:0019439 13 12 0,000 0,04612583 0,07241048 ! pyrimidine nucleotide biosynthetic process GO:0006221 12 12 0,000 0,04612583 0,07234885 ! neural tube closure GO:0001843 13 12 0,000 0,04612583 0,07228733 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! regulation of mitotic metaphase/anaphase transition GO:0030071 13 12 0,000 0,04612583 0,07222591 ! negative regulation of translation GO:0017148 12 12 0,000 0,04612583 0,0721646 ! regulation of microtubule polymerization or depolymerization GO:0031110 12 12 0,000 0,04612583 0,07210339 ! chemotaxis GO:0006935 90 89 1,000 0,04711922 0,07359384 GO:0042330|taxis, ! DNA replication GO:0006260 91 91 1,000 0,04903884 0,07652717 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 13 13 0,000 0,04987577 0,07776738 GO:0016444|somatic cell DNA recombination, ! negative regulation of actin filament polymerization GO:0030837 13 13 0,000 0,04987577 0,07770164 ! phenol metabolic process GO:0018958 13 13 0,000 0,04987577 0,07763601 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, GO:0009712|catechol metabolic process, ! gluconeogenesis GO:0006094 13 13 0,000 0,04987577 0,0775705 ! negative regulation of hormone secretion GO:0046888 13 13 0,000 0,04987577 0,07750509 ! 2'-deoxyribonucleotide metabolic process GO:0009394 13 13 0,000 0,04987577 0,0774398 GO:0019692|deoxyribose phosphate metabolic process, ! intra-Golgi vesicle-mediated transport GO:0006891 13 13 0,000 0,04987577 0,07737461 ! glycosaminoglycan biosynthetic process GO:0006024 13 13 0,000 0,04987577 0,07730954 ! positive regulation of JAK-STAT cascade GO:0046427 13 13 0,000 0,04987577 0,07724457 ! regeneration GO:0031099 13 13 0,000 0,04987577 0,07717972 ! keratinization GO:0031424 13 13 0,000 0,04987577 0,07711497 ! post-embryonic development GO:0009791 14 13 0,000 0,04987577 0,07705033 ! negative regulation of protein modification process GO:0031400 13 13 0,000 0,04987577 0,0769858 ! patterning of blood vessels GO:0001569 13 13 0,000 0,04987577 0,07692137 ! regulation of DNA recombination GO:0000018 13 13 0,000 0,04987577 0,07685706 ! regulation of innate immune response GO:0045088 13 13 0,000 0,04987577 0,07679285 ! multicellular organismal macromolecule metabolic process GO:0044259 13 13 0,000 0,04987577 0,07672875 ! response to corticosteroid stimulus GO:0031960 13 13 0,000 0,04987577 0,07666476 GO:0051384|response to glucocorticoid stimulus, ! multicellular organismal catabolic process GO:0044243 13 13 0,000 0,04987577 0,07660087 ! autophagy GO:0006914 13 13 0,000 0,04987577 0,07653709 ! receptor metabolic process GO:0043112 14 13 0,000 0,04987577 0,07647341 ! actin filament bundle formation GO:0051017 13 13 0,000 0,04987577 0,07640984 ! negative regulation of protein catabolic process GO:0042177 13 13 0,000 0,04987577 0,07634638 ! ureteric bud development GO:0001657 13 13 0,000 0,04987577 0,07628302 ! coenzyme catabolic process GO:0009109 13 13 0,000 0,04987577 0,07621977 GO:0046356|acetyl-CoA catabolic process, GO:0006099|tricarboxylic acid cycle, ! purine nucleoside monophosphate metabolic process GO:0009126 13 13 0,000 0,04987577 0,07615662 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of peptide secretion GO:0002791 13 13 0,000 0,04987577 0,07609358 ! regulation of viral reproduction GO:0050792 13 13 0,000 0,04987577 0,07603064 ! nucleobase metabolic process GO:0009112 13 13 0,000 0,04987577 0,0759678 ! regulation of axonogenesis GO:0050770 14 13 0,000 0,04987577 0,07590507 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 14 13 0,000 0,04987577 0,07584244 ! nucleotide-excision repair, DNA gap filling GO:0006297 13 13 0,000 0,04987577 0,07577992 ! vasodilation GO:0042311 14 13 0,000 0,04987577 0,0757175 ! positive regulation of leukocyte mediated immunity GO:0002705 13 13 0,000 0,04987577 0,07565518 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 13 13 0,000 0,04987577 0,07559296 ! glycosphingolipid metabolic process GO:0006687 13 13 0,000 0,04987577 0,07553085 GO:0006664|glycolipid metabolic process, ! neural crest cell migration GO:0001755 14 13 0,000 0,04987577 0,07546884 ! neutrophil chemotaxis GO:0030593 14 13 0,000 0,04987577 0,07540692 ! long-chain fatty acid transport GO:0015909 13 13 0,000 0,04987577 0,07534512 ! immunoglobulin production GO:0002377 13 13 0,000 0,04987577 0,07528341 GO:0002440|production of molecular mediator of immune response, ! negative regulation of Wnt receptor signaling pathway GO:0030178 13 13 0,000 0,04987577 0,0752218 ! negative regulation of intracellular transport GO:0032387 13 13 0,000 0,04987577 0,0751603 ! cell-cell junction organization GO:0045216 13 13 0,000 0,04987577 0,07509889 ! negative regulation of myeloid cell differentiation GO:0045638 13 13 0,000 0,04987577 0,07503758 ! response to cytokine stimulus GO:0034097 13 13 0,000 0,04987577 0,07497638 ! activation of JUN kinase activity GO:0007257 13 13 0,000 0,04987577 0,07491527 ! terpenoid metabolic process GO:0006721 13 13 0,000 0,04987577 0,07485427 ! alkene biosynthetic process GO:0043450 13 13 0,000 0,04987577 0,07479336 GO:0019370|leukotriene biosynthetic process, ! purine nucleotide catabolic process GO:0006195 13 13 0,000 0,04987577 0,07473255 ! porphyrin biosynthetic process GO:0006779 13 13 0,000 0,04987577 0,07467185 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of cytokine production GO:0001818 13 13 0,000 0,04987577 0,07461123 ! camera-type eye morphogenesis GO:0048593 13 13 0,000 0,04987577 0,07455072 ! pyrimidine nucleoside metabolic process GO:0006213 13 13 0,000 0,04987577 0,07449031 ! blastocyst development GO:0001824 13 13 0,000 0,04987577 0,07442999 ! telomere organization GO:0032200 13 13 0,000 0,04987577 0,07436977 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 13 13 0,000 0,04987577 0,07430965 ! regulation of amine transport GO:0051952 13 13 0,000 0,04987577 0,07424963 ! tissue homeostasis GO:0001894 13 13 0,000 0,04987577 0,0741897 GO:0048871|multicellular organismal homeostasis, ! inner ear receptor cell differentiation GO:0060113 13 13 0,000 0,04987577 0,07412987 ! fatty acid metabolic process GO:0006631 93 92 1,000 0,05000936 0,07426854 ! positive regulation of immune system process GO:0002684 92 92 1,000 0,05000936 0,07420874 ! tissue morphogenesis GO:0048729 94 93 1,000 0,05098694 0,07559849 ! pattern specification process GO:0007389 96 94 1,000 0,05197149 0,07699635 ! epidermis development GO:0008544 94 94 1,000 0,05197149 0,07693451 ! neuron fate commitment GO:0048663 14 14 0,000 0,05361151 0,07929857 ! sulfur amino acid metabolic process GO:0000096 14 14 0,000 0,05361151 0,07923498 ! regulation of interferon-gamma production GO:0032649 14 14 0,000 0,05361151 0,07917149 ! pyruvate metabolic process GO:0006090 14 14 0,000 0,05361151 0,0791081 ! cellular aldehyde metabolic process GO:0006081 14 14 0,000 0,05361151 0,07904481 ! acetyl-CoA metabolic process GO:0006084 14 14 0,000 0,05361151 0,07898163 ! cellular iron ion homeostasis GO:0006879 14 14 0,000 0,05361151 0,07891854 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 14 14 0,000 0,05361151 0,07885556 ! regulation of neuron projection development GO:0010975 15 14 0,000 0,05361151 0,07879268 ! protein amino acid deacetylation GO:0006476 14 14 0,000 0,05361151 0,07872989 ! aminoglycan biosynthetic process GO:0006023 14 14 0,000 0,05361151 0,07866721 ! vesicle docking GO:0048278 14 14 0,000 0,05361151 0,07860463 ! superoxide metabolic process GO:0006801 15 14 0,000 0,05361151 0,07854214 ! macromolecular complex disassembly GO:0032984 15 14 0,000 0,05361151 0,07847976 ! calcium-dependent cell-cell adhesion GO:0016339 14 14 0,000 0,05361151 0,07841747 ! mechanoreceptor differentiation GO:0042490 14 14 0,000 0,05361151 0,07835529 ! isoprenoid biosynthetic process GO:0008299 14 14 0,000 0,05361151 0,0782932 ! negative regulation of epithelial cell proliferation GO:0050680 14 14 0,000 0,05361151 0,07823121 ! immune response-activating cell surface receptor signaling pathway GO:0002429 14 14 0,000 0,05361151 0,07816932 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! response to retinoic acid GO:0032526 14 14 0,000 0,05361151 0,07810752 GO:0033189|response to vitamin A, ! multicellular organismal response to stress GO:0033555 14 14 0,000 0,05361151 0,07804583 ! lysosome organization GO:0007040 14 14 0,000 0,05361151 0,07798423 ! actin polymerization or depolymerization GO:0008154 15 14 0,000 0,05361151 0,07792273 ! D-ribose metabolic process GO:0006014 14 14 0,000 0,05361151 0,07786132 ! negative regulation of phosphorus metabolic process GO:0010563 14 14 0,000 0,05361151 0,07780001 GO:0045936|negative regulation of phosphate metabolic process, ! peptide transport GO:0015833 14 14 0,000 0,05361151 0,0777388 ! primary neural tube formation GO:0014020 15 14 0,000 0,05361151 0,07767769 ! peptide cross-linking GO:0018149 14 14 0,000 0,05361151 0,07761667 ! vitamin biosynthetic process GO:0009110 14 14 0,000 0,05361151 0,07755574 ! response to organic cyclic substance GO:0014070 15 14 0,000 0,05361151 0,07749492 ! leukotriene metabolic process GO:0006691 14 14 0,000 0,05361151 0,07743418 ! regulation of vasoconstriction GO:0019229 14 14 0,000 0,05361151 0,07737355 ! formation of primary germ layer GO:0001704 14 14 0,000 0,05361151 0,077313 GO:0001707|mesoderm formation, ! DNA modification GO:0006304 14 14 0,000 0,05361151 0,07725255 ! collagen fibril organization GO:0030199 14 14 0,000 0,05361151 0,0771922 ! proteoglycan biosynthetic process GO:0030166 14 14 0,000 0,05361151 0,07713194 ! regulation of blood coagulation GO:0030193 15 14 0,000 0,05361151 0,07707178 ! positive regulation of inflammatory response GO:0050729 14 14 0,000 0,05361151 0,07701171 ! group transfer coenzyme metabolic process GO:0006752 14 14 0,000 0,05361151 0,07695173 ! positive regulation of osteoblast differentiation GO:0045669 14 14 0,000 0,05361151 0,07689184 ! neuromuscular process controlling balance GO:0050885 14 14 0,000 0,05361151 0,07683205 ! aspartate family amino acid metabolic process GO:0009066 14 14 0,000 0,05361151 0,07677235 ! response to molecule of bacterial origin GO:0002237 14 14 0,000 0,05361151 0,07671275 ! negative regulation of protein polymerization GO:0032272 14 14 0,000 0,05361151 0,07665323 ! regulation of cell growth GO:0001558 97 96 1,000 0,0539613 0,07709355 ! blood circulation GO:0008015 99 98 1,000 0,05597828 0,07991322 GO:0003013|circulatory system process, ! ectoderm development GO:0007398 99 99 1,000 0,05699679 0,08130425 ! positive regulation of fibroblast proliferation GO:0048146 15 15 0,000 0,05733311 0,08172074 ! negative regulation of actin filament depolymerization GO:0030835 15 15 0,000 0,05733311 0,08165759 ! positive regulation of ossification GO:0045778 15 15 0,000 0,05733311 0,08159453 GO:0046852|positive regulation of bone remodeling, GO:0034105|positive regulation of tissue remodeling, ! negative regulation of protein complex assembly GO:0031333 15 15 0,000 0,05733311 0,08153158 ! protein amino acid O-linked glycosylation GO:0006493 15 15 0,000 0,05733311 0,08146871 ! cellular polysaccharide biosynthetic process GO:0033692 15 15 0,000 0,05733311 0,08140595 ! proteoglycan metabolic process GO:0006029 15 15 0,000 0,05733311 0,08134328 ! response to vitamin GO:0033273 15 15 0,000 0,05733311 0,08128071 ! striated muscle cell differentiation GO:0051146 16 15 0,000 0,05733311 0,08121823 ! odontogenesis of dentine-containing tooth GO:0042475 15 15 0,000 0,05733311 0,08115585 ! detection of stimulus involved in sensory perception GO:0050906 16 15 0,000 0,05733311 0,08109357 ! ovarian follicle development GO:0001541 15 15 0,000 0,05733311 0,08103138 ! antigen processing and presentation of peptide antigen GO:0048002 15 15 0,000 0,05733311 0,08096929 ! regulation of smooth muscle contraction GO:0006940 15 15 0,000 0,05733311 0,08090729 ! deoxyribonucleotide metabolic process GO:0009262 15 15 0,000 0,05733311 0,08084539 ! complement activation, classical pathway GO:0006958 15 15 0,000 0,05733311 0,08078358 ! heme metabolic process GO:0042168 15 15 0,000 0,05733311 0,08072187 ! mesoderm morphogenesis GO:0048332 15 15 0,000 0,05733311 0,08066025 ! chromosome condensation GO:0030261 15 15 0,000 0,05733311 0,08059872 ! response to mechanical stimulus GO:0009612 15 15 0,000 0,05733311 0,08053729 ! hydrogen peroxide metabolic process GO:0042743 15 15 0,000 0,05733311 0,08047595 ! regulation of biomineral formation GO:0070167 15 15 0,000 0,05733311 0,0804147 GO:0030500|regulation of bone mineralization, ! regulation of production of molecular mediator of immune response GO:0002700 15 15 0,000 0,05733311 0,08035355 ! cyclic nucleotide biosynthetic process GO:0009190 15 15 0,000 0,05733311 0,08029249 ! cholesterol biosynthetic process GO:0006695 15 15 0,000 0,05733311 0,08023153 ! phospholipid transport GO:0015914 15 15 0,000 0,05733311 0,08017065 ! leukocyte homeostasis GO:0001776 15 15 0,000 0,05733311 0,08010987 ! regulation of cytokine secretion GO:0050707 15 15 0,000 0,05733311 0,08004918 ! glutathione metabolic process GO:0006749 16 15 0,000 0,05733311 0,07998859 ! nicotinamide metabolic process GO:0006769 15 15 0,000 0,05733311 0,07992808 GO:0046496|nicotinamide nucleotide metabolic process, ! positive regulation of B cell activation GO:0050871 15 15 0,000 0,05733311 0,07986767 ! positive regulation of myeloid cell differentiation GO:0045639 16 15 0,000 0,05733311 0,07980734 ! cellular alkene metabolic process GO:0043449 15 15 0,000 0,05733311 0,07974711 ! negative regulation of transcription factor activity GO:0043433 16 15 0,000 0,05733311 0,07968697 GO:0090048|negative regulation of transcription regulator activity, ! somatic diversification of immune receptors GO:0002200 15 15 0,000 0,05733311 0,07962692 ! positive regulation of immune effector process GO:0002699 15 15 0,000 0,05733311 0,07956696 ! response to hormone stimulus GO:0009725 102 100 1,000 0,05802191 0,08046228 ! response to other organism GO:0051707 101 100 1,000 0,05802191 0,08040179 ! hemopoiesis GO:0030097 104 100 1,000 0,05802191 0,08034138 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 16 16 0,000 0,06104061 0,08445784 ! negative regulation of adenylate cyclase activity GO:0007194 16 16 0,000 0,06104061 0,08439449 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! alkaloid metabolic process GO:0009820 16 16 0,000 0,06104061 0,08433122 ! regulation of synaptic plasticity GO:0048167 16 16 0,000 0,06104061 0,08426805 ! spliceosomal snRNP biogenesis GO:0000387 16 16 0,000 0,06104061 0,08420498 ! learning GO:0007612 16 16 0,000 0,06104061 0,084142 ! circadian rhythm GO:0007623 16 16 0,000 0,06104061 0,08407911 ! inner ear morphogenesis GO:0042472 16 16 0,000 0,06104061 0,08401632 ! positive regulation of mitosis GO:0045840 16 16 0,000 0,06104061 0,08395362 GO:0051785|positive regulation of nuclear division, ! vacuole organization GO:0007033 16 16 0,000 0,06104061 0,08389101 ! cellular response to reactive oxygen species GO:0034614 16 16 0,000 0,06104061 0,0838285 ! positive regulation of cytoskeleton organization GO:0051495 16 16 0,000 0,06104061 0,08376608 ! vesicle targeting GO:0006903 17 16 0,000 0,06104061 0,08370376 ! triglyceride metabolic process GO:0006641 16 16 0,000 0,06104061 0,08364152 ! iron ion homeostasis GO:0055072 16 16 0,000 0,06104061 0,08357938 ! regulation of myeloid leukocyte differentiation GO:0002761 17 16 0,000 0,06104061 0,08351733 ! lymphocyte proliferation GO:0046651 16 16 0,000 0,06104061 0,08345538 ! regulation of systemic arterial blood pressure GO:0003073 17 16 0,000 0,06104061 0,08339351 ! cell fate specification GO:0001708 16 16 0,000 0,06104061 0,08333174 ! pentose metabolic process GO:0019321 16 16 0,000 0,06104061 0,08327006 ! positive regulation of MAPKKK cascade GO:0043410 17 16 0,000 0,06104061 0,08320847 ! regulation of microtubule cytoskeleton organization GO:0070507 16 16 0,000 0,06104061 0,08314697 ! cofactor catabolic process GO:0051187 16 16 0,000 0,06104061 0,08308556 ! ethanolamine and derivative metabolic process GO:0042439 17 16 0,000 0,06104061 0,08302424 ! serine family amino acid metabolic process GO:0009069 16 16 0,000 0,06104061 0,08296302 ! glutamine family amino acid catabolic process GO:0009065 17 16 0,000 0,06104061 0,08290188 ! porphyrin metabolic process GO:0006778 16 16 0,000 0,06104061 0,08284083 GO:0033013|tetrapyrrole metabolic process, ! embryonic epithelial tube formation GO:0001838 17 16 0,000 0,06104061 0,08277987 GO:0001841|neural tube formation, ! regulation of JUN kinase activity GO:0043506 17 16 0,000 0,06104061 0,08271901 GO:0043507|positive regulation of JUN kinase activity, ! regulation of cell morphogenesis involved in differentiation GO:0010769 17 16 0,000 0,06104061 0,08265823 ! response to xenobiotic stimulus GO:0009410 16 16 0,000 0,06104061 0,08259754 ! regulation of coagulation GO:0050818 17 16 0,000 0,06104061 0,08253694 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 17 17 0,000 0,06473407 0,08746693 ! regulation of actin filament depolymerization GO:0030834 17 17 0,000 0,06473407 0,08740285 ! phosphoinositide biosynthetic process GO:0046489 17 17 0,000 0,06473407 0,08733887 ! regulation of transmembrane transport GO:0034762 17 17 0,000 0,06473407 0,08727498 ! nucleotide-excision repair, DNA damage removal GO:0000718 18 17 0,000 0,06473407 0,08721118 ! leukocyte adhesion GO:0007159 17 17 0,000 0,06473407 0,08714748 ! dicarboxylic acid metabolic process GO:0043648 18 17 0,000 0,06473407 0,08708386 ! sensory perception of smell GO:0007608 17 17 0,000 0,06473407 0,08702035 ! cell junction assembly GO:0034329 18 17 0,000 0,06473407 0,08695692 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 17 17 0,000 0,06473407 0,08689359 ! embryonic skeletal system morphogenesis GO:0048704 17 17 0,000 0,06473407 0,08683035 ! cellular carbohydrate biosynthetic process GO:0034637 17 17 0,000 0,06473407 0,0867672 ! development of primary male sexual characteristics GO:0046546 17 17 0,000 0,06473407 0,08670414 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 17 17 0,000 0,06473407 0,08664117 ! neural crest cell development GO:0014032 19 17 0,000 0,06473407 0,0865783 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 18 17 0,000 0,06473407 0,08651551 ! immune response-activating signal transduction GO:0002757 17 17 0,000 0,06473407 0,08645282 GO:0002764|immune response-regulating signal transduction, ! cell recognition GO:0008037 18 17 0,000 0,06473407 0,08639022 ! positive regulation of protein secretion GO:0050714 17 17 0,000 0,06473407 0,08632771 ! regulation of osteoblast differentiation GO:0045667 17 17 0,000 0,06473407 0,08626529 ! pyridine nucleotide metabolic process GO:0019362 17 17 0,000 0,06473407 0,08620296 ! pigmentation GO:0043473 17 17 0,000 0,06473407 0,08614072 ! myeloid leukocyte activation GO:0002274 18 17 0,000 0,06473407 0,08607857 ! adult locomotory behavior GO:0008344 17 17 0,000 0,06473407 0,08601651 ! embryonic organ development GO:0048568 17 17 0,000 0,06473407 0,08595454 ! regulation of calcium ion transport GO:0051924 17 17 0,000 0,06473407 0,08589265 ! liver development GO:0001889 17 17 0,000 0,06473407 0,08583086 ! gene silencing GO:0016458 17 17 0,000 0,06473407 0,08576916 ! mRNA export from nucleus GO:0006406 18 18 0,000 0,06841354 0,09057913 ! icosanoid biosynthetic process GO:0046456 18 18 0,000 0,06841354 0,09051411 ! meiosis I GO:0007127 18 18 0,000 0,06841354 0,09044918 ! regulation of metal ion transport GO:0010959 18 18 0,000 0,06841354 0,09038434 ! membrane docking GO:0022406 18 18 0,000 0,06841354 0,09031959 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 18 18 0,000 0,06841354 0,09025494 ! mononuclear cell proliferation GO:0032943 18 18 0,000 0,06841354 0,09019038 GO:0070661|leukocyte proliferation, ! response to calcium ion GO:0051592 18 18 0,000 0,06841354 0,09012591 ! negative regulation of response to external stimulus GO:0032102 18 18 0,000 0,06841354 0,09006154 ! cholesterol homeostasis GO:0042632 18 18 0,000 0,06841354 0,08999725 GO:0055092|sterol homeostasis, ! striated muscle contraction GO:0006941 18 18 0,000 0,06841354 0,08993306 ! neutral lipid metabolic process GO:0006638 18 18 0,000 0,06841354 0,08986896 GO:0006639|acylglycerol metabolic process, ! negative regulation of DNA binding GO:0043392 19 18 0,000 0,06841354 0,08980495 ! ceramide metabolic process GO:0006672 18 18 0,000 0,06841354 0,08974103 GO:0046519|sphingoid metabolic process, ! ribonucleoside monophosphate metabolic process GO:0009161 18 18 0,000 0,06841354 0,08967721 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! telencephalon development GO:0021537 19 18 0,000 0,06841354 0,08961347 ! hexose biosynthetic process GO:0019319 18 18 0,000 0,06841354 0,08954982 ! negative regulation of MAP kinase activity GO:0043407 18 18 0,000 0,06841354 0,08948627 ! BMP signaling pathway GO:0030509 18 18 0,000 0,06841354 0,0894228 ! regulation of microtubule-based process GO:0032886 18 18 0,000 0,06841354 0,08935943 ! negative regulation of catabolic process GO:0009895 18 18 0,000 0,06841354 0,08929614 ! establishment of vesicle localization GO:0051650 19 18 0,000 0,06841354 0,08923295 ! activation of adenylate cyclase activity GO:0007190 19 19 0,000 0,07207906 0,09394746 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 19 19 0,000 0,07207906 0,09388107 GO:0006956|complement activation, ! glial cell differentiation GO:0010001 19 19 0,000 0,07207906 0,09381477 ! regulation of JAK-STAT cascade GO:0046425 19 19 0,000 0,07207906 0,09374856 ! feeding behavior GO:0007631 19 19 0,000 0,07207906 0,09368245 ! peroxisome organization GO:0007031 19 19 0,000 0,07207906 0,09361643 ! positive regulation of T cell proliferation GO:0042102 19 19 0,000 0,07207906 0,0935505 ! regulation of striated muscle tissue development GO:0016202 20 19 0,000 0,07207906 0,09348467 ! multicellular organismal metabolic process GO:0044236 19 19 0,000 0,07207906 0,09341893 ! metanephros development GO:0001656 19 19 0,000 0,07207906 0,09335328 ! ribonucleoside metabolic process GO:0009119 19 19 0,000 0,07207906 0,09328772 ! cellular response to oxidative stress GO:0034599 19 19 0,000 0,07207906 0,09322226 ! regulation of lymphocyte mediated immunity GO:0002706 19 19 0,000 0,07207906 0,09315688 ! positive regulation of T cell differentiation GO:0045582 19 19 0,000 0,07207906 0,0930916 ! nuclear-transcribed mRNA catabolic process GO:0000956 19 19 0,000 0,07207906 0,09302641 ! hormone biosynthetic process GO:0042446 19 19 0,000 0,07207906 0,09296131 ! biogenic amine biosynthetic process GO:0042401 20 19 0,000 0,07207906 0,0928963 ! dorsal/ventral pattern formation GO:0009953 19 19 0,000 0,07207906 0,09283139 ! eye morphogenesis GO:0048592 19 19 0,000 0,07207906 0,09276656 ! response to heat GO:0009408 19 19 0,000 0,07207906 0,09270182 ! vesicle localization GO:0051648 20 19 0,000 0,07207906 0,09263718 ! regulation of muscle development GO:0048634 21 20 0,000 0,0757307 0,09726249 ! establishment or maintenance of cell polarity GO:0007163 21 20 0,000 0,0757307 0,09719476 ! negative regulation of binding GO:0051100 21 20 0,000 0,0757307 0,09712712 ! organic ether metabolic process GO:0018904 20 20 0,000 0,0757307 0,09705958 GO:0006662|glycerol ether metabolic process, ! cytoskeleton-dependent intracellular transport GO:0030705 20 20 0,000 0,0757307 0,09699213 ! neural tube development GO:0021915 21 20 0,000 0,0757307 0,09692478 ! nucleus organization GO:0006997 20 20 0,000 0,0757307 0,09685751 ! phagocytosis GO:0006909 21 20 0,000 0,0757307 0,09679035 ! unsaturated fatty acid biosynthetic process GO:0006636 20 20 0,000 0,0757307 0,09672327 ! protein targeting to membrane GO:0006612 22 20 0,000 0,0757307 0,09665629 ! cyclic nucleotide metabolic process GO:0009187 20 20 0,000 0,0757307 0,0965894 ! chromatin remodeling GO:0006338 20 20 0,000 0,0757307 0,0965226 ! detection of abiotic stimulus GO:0009582 21 20 0,000 0,0757307 0,09645589 ! female gamete generation GO:0007292 20 20 0,000 0,0757307 0,09638928 ! negative regulation of neuron apoptosis GO:0043524 21 20 0,000 0,0757307 0,09632276 ! monosaccharide biosynthetic process GO:0046364 20 20 0,000 0,0757307 0,09625633 ! RNA modification GO:0009451 20 20 0,000 0,0757307 0,09618999 ! single fertilization GO:0007338 21 20 0,000 0,0757307 0,09612374 ! regulation of B cell activation GO:0050864 20 20 0,000 0,0757307 0,09605759 ! mitotic sister chromatid segregation GO:0000070 21 21 0,000 0,07936849 0,10060257 ! mRNA catabolic process GO:0006402 21 21 0,000 0,07936849 0,10053342 ! positive regulation of adenylate cyclase activity GO:0045762 21 21 0,000 0,07936849 0,10046438 GO:0051349|positive regulation of lyase activity, GO:0031281|positive regulation of cyclase activity, ! protein amino acid lipidation GO:0006497 21 21 0,000 0,07936849 0,10039542 ! receptor-mediated endocytosis GO:0006898 21 21 0,000 0,07936849 0,10032657 ! ear morphogenesis GO:0042471 21 21 0,000 0,07936849 0,1002578 ! organic anion transport GO:0015711 21 21 0,000 0,07936849 0,10018913 ! cholesterol transport GO:0030301 21 21 0,000 0,07936849 0,10012056 GO:0015918|sterol transport, ! spliceosome assembly GO:0000245 22 21 0,000 0,07936849 0,10005207 ! regulation of Rab protein signal transduction GO:0032483 21 21 0,000 0,07936849 0,09998369 GO:0032313|regulation of Rab GTPase activity, ! regulation of leukocyte mediated immunity GO:0002703 21 21 0,000 0,07936849 0,09991539 ! regulation of multicellular organism growth GO:0040014 21 21 0,000 0,07936849 0,09984719 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 21 21 0,000 0,07936849 0,09977908 ! regulation of proteolysis GO:0030162 21 21 0,000 0,07936849 0,09971107 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 21 21 0,000 0,07936849 0,09964314 ! negative regulation of protein transport GO:0051224 21 21 0,000 0,07936849 0,09957531 ! RNA export from nucleus GO:0006405 22 22 0,000 0,0829925 0,10405114 ! sister chromatid segregation GO:0000819 22 22 0,000 0,0829925 0,1039804 ! cellular amide metabolic process GO:0043603 22 22 0,000 0,0829925 0,10390977 ! regulation of ion transport GO:0043269 22 22 0,000 0,0829925 0,10383922 ! odontogenesis GO:0042476 22 22 0,000 0,0829925 0,10376878 ! cell junction organization GO:0034330 23 22 0,000 0,0829925 0,10369842 ! positive regulation of lymphocyte proliferation GO:0050671 22 22 0,000 0,0829925 0,10362817 GO:0032946|positive regulation of mononuclear cell proliferation, GO:0070665|positive regulation of leukocyte proliferation, GO:0070668|positive regulation of mast cell proliferation, ! hormone-mediated signaling GO:0009755 22 22 0,000 0,0829925 0,10355801 ! embryonic skeletal system development GO:0048706 22 22 0,000 0,0829925 0,10348794 ! maintenance of protein location in cell GO:0032507 23 22 0,000 0,0829925 0,10341797 ! ovulation cycle process GO:0022602 22 22 0,000 0,0829925 0,10334809 ! spindle organization GO:0007051 22 22 0,000 0,0829925 0,10327831 ! pigment biosynthetic process GO:0046148 22 22 0,000 0,0829925 0,10320862 ! cell chemotaxis GO:0060326 23 22 0,000 0,0829925 0,10313903 GO:0030595|leukocyte chemotaxis, ! respiratory gaseous exchange GO:0007585 22 22 0,000 0,0829925 0,10306952 ! erythrocyte differentiation GO:0030218 23 22 0,000 0,0829925 0,10300012 ! male sex differentiation GO:0046661 22 22 0,000 0,0829925 0,1029308 ! sterol biosynthetic process GO:0016126 22 22 0,000 0,0829925 0,10286158 ! biopolymer methylation GO:0043414 22 22 0,000 0,0829925 0,10279246 GO:0032259|methylation, ! regulation of adaptive immune response GO:0002819 22 22 0,000 0,0829925 0,10272342 ! detection of external stimulus GO:0009581 23 22 0,000 0,0829925 0,10265448 ! neuron migration GO:0001764 22 22 0,000 0,0829925 0,10258563 ! regulation of Wnt receptor signaling pathway GO:0030111 23 22 0,000 0,0829925 0,10251687 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 22 22 0,000 0,0829925 0,10244821 ! positive regulation of lymphocyte differentiation GO:0045621 22 22 0,000 0,0829925 0,10237963 ! aerobic respiration GO:0009060 22 22 0,000 0,0829925 0,10231115 ! cytokine production GO:0001816 22 22 0,000 0,0829925 0,10224276 ! cytokinesis GO:0000910 23 22 0,000 0,0829925 0,10217447 ! pyrimidine nucleotide metabolic process GO:0006220 22 22 0,000 0,0829925 0,10210626 ! response to hydrogen peroxide GO:0042542 24 23 0,000 0,08660276 0,10647691 ! epithelial cell differentiation GO:0030855 23 23 0,000 0,08660276 0,10640593 ! viral infectious cycle GO:0019058 23 23 0,000 0,08660276 0,10633504 ! regulation of hormone secretion GO:0046883 23 23 0,000 0,08660276 0,10626424 ! response to estrogen stimulus GO:0043627 23 23 0,000 0,08660276 0,10619354 ! negative regulation of protein complex disassembly GO:0043242 23 23 0,000 0,08660276 0,10612293 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 23 23 0,000 0,08660276 0,10605242 ! induction of apoptosis by extracellular signals GO:0008624 23 23 0,000 0,08660276 0,105982 ! regulation of ARF protein signal transduction GO:0032012 23 23 0,000 0,08660276 0,10591167 ! endocrine system development GO:0035270 23 23 0,000 0,08660276 0,10584144 ! lipoprotein biosynthetic process GO:0042158 23 23 0,000 0,08660276 0,1057713 ! female gonad development GO:0008585 23 23 0,000 0,08660276 0,10570125 ! lipid homeostasis GO:0055088 23 23 0,000 0,08660276 0,1056313 ! Rho protein signal transduction GO:0007266 24 23 0,000 0,08660276 0,10556144 ! regulation of JNK cascade GO:0046328 25 23 0,000 0,08660276 0,10549167 ! cell projection assembly GO:0030031 25 23 0,000 0,08660276 0,10542199 ! gliogenesis GO:0042063 24 24 0,000 0,09019934 0,10972765 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 26 24 0,000 0,09019934 0,10965527 ! cellular amino acid biosynthetic process GO:0008652 24 24 0,000 0,09019934 0,10958298 ! heterocycle biosynthetic process GO:0018130 24 24 0,000 0,09019934 0,10951079 ! nucleotide catabolic process GO:0009166 24 24 0,000 0,09019934 0,1094387 ! erythrocyte homeostasis GO:0034101 25 24 0,000 0,09019934 0,1093667 ! ovulation cycle GO:0042698 24 24 0,000 0,09019934 0,1092948 ! fertilization GO:0009566 25 24 0,000 0,09019934 0,10922299 ! maintenance of protein location GO:0045185 25 24 0,000 0,09019934 0,10915127 ! oxidoreduction coenzyme metabolic process GO:0006733 24 24 0,000 0,09019934 0,10907965 ! epithelial tube morphogenesis GO:0060562 25 24 0,000 0,09019934 0,10900812 ! glucan metabolic process GO:0044042 25 24 0,000 0,09019934 0,10893669 GO:0006073|cellular glucan metabolic process, GO:0005977|glycogen metabolic process, ! regulation of actin filament polymerization GO:0030833 25 25 0,000 0,09378228 0,11318974 ! negative regulation of secretion GO:0051048 26 25 0,000 0,09378228 0,11311567 ! protein amino acid N-linked glycosylation GO:0006487 25 25 0,000 0,09378228 0,11304169 ! sensory perception of chemical stimulus GO:0007606 25 25 0,000 0,09378228 0,1129678 ! cellular component disassembly GO:0022411 26 25 0,000 0,09378228 0,11289402 ! endosome transport GO:0016197 25 25 0,000 0,09378228 0,11282033 ! alcohol biosynthetic process GO:0046165 25 25 0,000 0,09378228 0,11274673 ! development of primary female sexual characteristics GO:0046545 25 25 0,000 0,09378228 0,11267323 GO:0046660|female sex differentiation, ! polysaccharide biosynthetic process GO:0000271 25 25 0,000 0,09378228 0,11259983 ! excretion GO:0007588 25 25 0,000 0,09378228 0,11252652 ! generation of a signal involved in cell-cell signaling GO:0003001 27 25 0,000 0,09378228 0,11245331 ! gastrulation GO:0007369 25 25 0,000 0,09378228 0,11238019 ! icosanoid metabolic process GO:0006690 25 25 0,000 0,09378228 0,11230717 ! regulation of endocytosis GO:0030100 25 25 0,000 0,09378228 0,11223425 ! positive regulation of cytokine production GO:0001819 25 25 0,000 0,09378228 0,11216141 ! positive regulation of defense response GO:0031349 26 26 0,000 0,09735163 0,11635476 ! glycolysis GO:0006096 26 26 0,000 0,09735163 0,11627936 ! transforming growth factor beta receptor signaling pathway GO:0007179 26 26 0,000 0,09735163 0,11620405 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 26 26 0,000 0,09735163 0,11612883 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 26 26 0,000 0,09735163 0,11605372 ! cellular defense response GO:0006968 26 26 0,000 0,09735163 0,1159787 ! positive regulation of cytokine biosynthetic process GO:0042108 26 26 0,000 0,09735163 0,11590378 ! regulation of protein secretion GO:0050708 26 26 0,000 0,09735163 0,11582895 ! germ cell development GO:0007281 27 26 0,000 0,09735163 0,11575422 ! regulation of blood vessel size GO:0050880 27 26 0,000 0,09735163 0,11567959 GO:0035150|regulation of tube size, ! pigment metabolic process GO:0042440 26 26 0,000 0,09735163 0,11560506 ! maintenance of location in cell GO:0051651 27 26 0,000 0,09735163 0,11553062 ! chloride transport GO:0006821 27 27 0,000 0,10090743 0,11967336 ! regulation of neurotransmitter levels GO:0001505 31 27 0,000 0,10090743 0,1195964 ! energy reserve metabolic process GO:0006112 28 27 0,000 0,10090743 0,11951954 ! learning or memory GO:0007611 28 27 0,000 0,10090743 0,11944277 ! cAMP-mediated signaling GO:0019933 27 27 0,000 0,10090743 0,11936611 ! peptide metabolic process GO:0006518 29 27 0,000 0,10090743 0,11928954 ! inner ear development GO:0048839 27 27 0,000 0,10090743 0,11921308 ! defense response to bacterium GO:0042742 27 27 0,000 0,10090743 0,11913671 ! glutamine family amino acid metabolic process GO:0009064 28 27 0,000 0,10090743 0,11906044 ! cell growth GO:0016049 27 27 0,000 0,10090743 0,11898426 ! tRNA aminoacylation for protein translation GO:0006418 28 28 0,000 0,10444975 0,12308241 GO:0043038|amino acid activation, GO:0043039|tRNA aminoacylation, ! stress-activated protein kinase signaling pathway GO:0031098 28 28 0,000 0,10444975 0,12300376 GO:0007254|JNK cascade, ! neuromuscular process GO:0050905 28 28 0,000 0,10444975 0,12292522 ! regulation of muscle contraction GO:0006937 28 28 0,000 0,10444975 0,12284677 ! unsaturated fatty acid metabolic process GO:0033559 28 28 0,000 0,10444975 0,12276842 ! sulfur compound biosynthetic process GO:0044272 28 28 0,000 0,10444975 0,12269018 ! keratinocyte differentiation GO:0030216 28 28 0,000 0,10444975 0,12261203 ! cartilage development GO:0051216 29 28 0,000 0,10444975 0,12253398 ! glycerophospholipid biosynthetic process GO:0046474 30 29 0,000 0,10797863 0,12659326 ! leukocyte migration GO:0050900 30 29 0,000 0,10797863 0,12651278 ! branching morphogenesis of a tube GO:0048754 29 29 0,000 0,10797863 0,12643241 ! antigen processing and presentation GO:0019882 29 29 0,000 0,10797863 0,12635213 ! DNA-dependent DNA replication GO:0006261 29 29 0,000 0,10797863 0,12627196 ! tRNA processing GO:0008033 29 29 0,000 0,10797863 0,12619189 ! regulation of gene expression, epigenetic GO:0040029 29 29 0,000 0,10797863 0,12611192 ! adult behavior GO:0030534 30 29 0,000 0,10797863 0,12603205 ! regulation of protein polymerization GO:0032271 29 29 0,000 0,10797863 0,12595228 ! transition metal ion transport GO:0000041 31 30 0,000 0,11149411 0,12997068 ! RNA catabolic process GO:0006401 30 30 0,000 0,11149411 0,12988852 ! response to reactive oxygen species GO:0000302 31 30 0,000 0,11149411 0,12980647 ! ER to Golgi vesicle-mediated transport GO:0006888 30 30 0,000 0,11149411 0,12972452 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 30 30 0,000 0,11149411 0,12964268 ! neuropeptide signaling pathway GO:0007218 30 30 0,000 0,11149411 0,12956094 ! regulation of protein complex disassembly GO:0043244 30 30 0,000 0,11149411 0,1294793 ! positive regulation of protein amino acid phosphorylation GO:0001934 30 30 0,000 0,11149411 0,12939776 ! skeletal system morphogenesis GO:0048705 31 30 0,000 0,11149411 0,12931633 ! response to temperature stimulus GO:0009266 30 30 0,000 0,11149411 0,129235 ! regulation of ossification GO:0030278 30 30 0,000 0,11149411 0,12915377 ! immunoglobulin mediated immune response GO:0016064 30 30 0,000 0,11149411 0,12907264 GO:0019724|B cell mediated immunity, ! regulation of inflammatory response GO:0050727 30 30 0,000 0,11149411 0,12899162 ! water-soluble vitamin metabolic process GO:0006767 30 30 0,000 0,11149411 0,12891069 ! vesicle organization GO:0016050 30 30 0,000 0,11149411 0,12882987 ! cellular amino acid derivative biosynthetic process GO:0042398 31 30 0,000 0,11149411 0,12874915 ! establishment of organelle localization GO:0051656 31 30 0,000 0,11149411 0,12866853 ! regulation of translational initiation GO:0006446 31 31 0,000 0,11499625 0,13262709 ! membrane fusion GO:0006944 31 31 0,000 0,11499625 0,13254415 ! negative regulation of cytoskeleton organization GO:0051494 32 31 0,000 0,11499625 0,13246131 ! lipoprotein metabolic process GO:0042157 31 31 0,000 0,11499625 0,13237857 ! ion transmembrane transport GO:0034220 31 31 0,000 0,11499625 0,13229594 GO:0015985|energy coupled proton transport, down electrochemical gradient, GO:0015986|ATP synthesis coupled proton transport, ! glycerolipid biosynthetic process GO:0045017 32 31 0,000 0,11499625 0,1322134 ! digestion GO:0007586 31 31 0,000 0,11499625 0,13213098 ! nucleoside metabolic process GO:0009116 31 31 0,000 0,11499625 0,13204865 ! regulation of heart contraction GO:0008016 31 31 0,000 0,11499625 0,13196643 ! sphingolipid metabolic process GO:0006665 31 31 0,000 0,11499625 0,13188431 ! camera-type eye development GO:0043010 31 31 0,000 0,11499625 0,13180229 ! extracellular matrix organization GO:0030198 31 31 0,000 0,11499625 0,13172038 ! ribonucleoprotein complex assembly GO:0022618 32 31 0,000 0,11499625 0,13163856 ! epidermal cell differentiation GO:0009913 31 31 0,000 0,11499625 0,13155685 ! regulation of myeloid cell differentiation GO:0045637 32 31 0,000 0,11499625 0,13147524 ! cell redox homeostasis GO:0045454 32 32 0,000 0,11848509 0,13538006 ! glucose catabolic process GO:0006007 32 32 0,000 0,11848509 0,13529618 ! glycosaminoglycan metabolic process GO:0030203 34 32 0,000 0,11848509 0,1352124 ! regulation of vesicle-mediated transport GO:0060627 33 32 0,000 0,11848509 0,13512873 ! cell maturation GO:0048469 32 32 0,000 0,11848509 0,13504516 ! morphogenesis of a branching structure GO:0001763 32 32 0,000 0,11848509 0,1349617 ! nuclear export GO:0051168 32 32 0,000 0,11848509 0,13487834 ! kidney development GO:0001822 32 32 0,000 0,11848509 0,13479508 ! protein maturation by peptide bond cleavage GO:0051605 32 32 0,000 0,11848509 0,13471192 ! maintenance of location GO:0051235 33 32 0,000 0,11848509 0,13462887 ! regulation of cellular response to stress GO:0080135 35 33 0,000 0,12196069 0,13849264 ! amino acid transport GO:0006865 33 33 0,000 0,12196069 0,13840736 ! regulation of protein complex assembly GO:0043254 33 33 0,000 0,12196069 0,13832219 ! membrane lipid metabolic process GO:0006643 33 33 0,000 0,12196069 0,13823712 ! regulation of actin polymerization or depolymerization GO:0008064 33 33 0,000 0,12196069 0,13815216 ! regulation of neuron differentiation GO:0045664 34 33 0,000 0,12196069 0,1380673 ! regulation of synaptic transmission GO:0050804 33 33 0,000 0,12196069 0,13798254 ! regulation of actin filament length GO:0030832 34 34 0,000 0,1254231 0,14181274 ! response to metal ion GO:0010038 34 34 0,000 0,1254231 0,14172579 ! ear development GO:0043583 34 34 0,000 0,1254231 0,14163895 ! muscle cell differentiation GO:0042692 35 34 0,000 0,1254231 0,14155221 ! cellular polysaccharide metabolic process GO:0044264 35 34 0,000 0,1254231 0,14146558 ! regulation of protein catabolic process GO:0042176 35 34 0,000 0,1254231 0,14137906 ! coenzyme biosynthetic process GO:0009108 34 34 0,000 0,1254231 0,14129264 ! nucleoside monophosphate biosynthetic process GO:0009124 34 34 0,000 0,1254231 0,14120633 ! regulation of lipid metabolic process GO:0019216 34 34 0,000 0,1254231 0,14112012 ! secondary metabolic process GO:0019748 34 34 0,000 0,1254231 0,14103402 ! negative regulation of response to stimulus GO:0048585 34 34 0,000 0,1254231 0,14094803 ! detection of stimulus GO:0051606 36 34 0,000 0,1254231 0,14086214 ! acute inflammatory response GO:0002526 35 35 0,000 0,12887235 0,14464783 ! regulation of cellular component size GO:0032535 35 35 0,000 0,12887235 0,14455979 ! regulation of cytokine biosynthetic process GO:0042035 35 35 0,000 0,12887235 0,14447186 ! mesoderm development GO:0007498 35 35 0,000 0,12887235 0,14438403 ! multicellular organism reproduction GO:0032504 36 35 0,000 0,12887235 0,14429632 GO:0048609|reproductive process in a multicellular organism, ! inorganic anion transport GO:0015698 35 35 0,000 0,12887235 0,1442087 ! response to steroid hormone stimulus GO:0048545 35 35 0,000 0,12887235 0,1441212 ! regulation of immune effector process GO:0002697 35 35 0,000 0,12887235 0,1440338 ! hydrogen transport GO:0006818 36 36 0,000 0,1323085 0,14778458 GO:0015992|proton transport, ! response to inorganic substance GO:0010035 36 36 0,000 0,1323085 0,14769507 ! aminoglycan metabolic process GO:0006022 38 36 0,000 0,1323085 0,14760567 ! oxygen and reactive oxygen species metabolic process GO:0006800 37 36 0,000 0,1323085 0,14751637 ! regulation of mitosis GO:0007088 37 36 0,000 0,1323085 0,14742718 GO:0051783|regulation of nuclear division, ! embryonic limb morphogenesis GO:0030326 36 36 0,000 0,1323085 0,1473381 GO:0035113|embryonic appendage morphogenesis, ! RNA elongation from RNA polymerase II promoter GO:0006368 36 36 0,000 0,1323085 0,14724913 ! positive regulation of organelle organization GO:0010638 36 36 0,000 0,1323085 0,14716027 ! heterocycle catabolic process GO:0046700 36 36 0,000 0,1323085 0,14707151 ! integrin-mediated signaling pathway GO:0007229 36 36 0,000 0,1323085 0,14698286 ! regulation of transmission of nerve impulse GO:0051969 36 36 0,000 0,1323085 0,14689431 ! gonad development GO:0008406 36 36 0,000 0,1323085 0,14680588 ! activation of immune response GO:0002253 36 36 0,000 0,1323085 0,14671754 ! coagulation GO:0050817 39 36 0,000 0,1323085 0,14662932 GO:0007596|blood coagulation, ! regulation of adenylate cyclase activity GO:0045761 37 37 0,000 0,13573159 0,15033253 GO:0031279|regulation of cyclase activity, GO:0051339|regulation of lyase activity, ! meiosis GO:0007126 37 37 0,000 0,13573159 0,15024224 GO:0051327|M phase of meiotic cell cycle, ! lymphocyte mediated immunity GO:0002449 37 37 0,000 0,13573159 0,15015206 ! eye development GO:0001654 37 37 0,000 0,13573159 0,15006198 ! ATP synthesis coupled electron transport GO:0042773 37 37 0,000 0,13573159 0,14997202 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! cellular amino acid catabolic process GO:0009063 38 37 0,000 0,13573159 0,14988216 ! regulation of Rho protein signal transduction GO:0035023 37 37 0,000 0,13573159 0,14979241 ! positive regulation of secretion GO:0051047 39 38 0,000 0,13914168 0,15346387 ! neurotransmitter transport GO:0006836 40 38 0,000 0,13914168 0,15337208 ! cellular hormone metabolic process GO:0034754 39 38 0,000 0,13914168 0,15328041 ! cell-matrix adhesion GO:0007160 39 38 0,000 0,13914168 0,15318884 ! chromosome segregation GO:0007059 38 38 0,000 0,13914168 0,15309739 ! urogenital system development GO:0001655 38 38 0,000 0,13914168 0,15300604 ! hexose catabolic process GO:0019320 38 38 0,000 0,13914168 0,1529148 ! RNA elongation GO:0006354 38 38 0,000 0,13914168 0,15282367 ! meiotic cell cycle GO:0051321 38 38 0,000 0,13914168 0,15273265 ! regulation of neurological system process GO:0031644 38 38 0,000 0,13914168 0,15264174 ! regulation of cAMP biosynthetic process GO:0030817 39 39 0,000 0,14253881 0,15627545 ! hemostasis GO:0007599 42 39 0,000 0,14253881 0,15618254 ! positive regulation of protein modification process GO:0031401 39 39 0,000 0,14253881 0,15608974 ! response to unfolded protein GO:0006986 39 39 0,000 0,14253881 0,15599705 ! nucleoside monophosphate metabolic process GO:0009123 39 39 0,000 0,14253881 0,15590447 ! fatty acid biosynthetic process GO:0006633 39 39 0,000 0,14253881 0,155812 ! cytokine-mediated signaling pathway GO:0019221 39 39 0,000 0,14253881 0,15571964 ! intracellular protein transmembrane transport GO:0065002 39 39 0,000 0,14253881 0,15562739 ! regulation of MAPKKK cascade GO:0043408 41 39 0,000 0,14253881 0,15553525 ! positive regulation of T cell activation GO:0050870 39 39 0,000 0,14253881 0,15544322 ! limb development GO:0060173 39 39 0,000 0,14253881 0,15535129 GO:0048736|appendage development, GO:0035107|appendage morphogenesis, ! regulation of cAMP metabolic process GO:0030814 40 40 0,000 0,14592304 0,15894572 ! DNA catabolic process GO:0006308 41 40 0,000 0,14592304 0,15885183 ! myeloid cell differentiation GO:0030099 42 40 0,000 0,14592304 0,15875806 ! organelle localization GO:0051640 41 40 0,000 0,14592304 0,1586644 ! regulation of nucleotide biosynthetic process GO:0030808 41 41 0,000 0,14929439 0,16223441 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! amine catabolic process GO:0009310 42 41 0,000 0,14929439 0,16213881 ! elevation of cytosolic calcium ion concentration GO:0007204 41 41 0,000 0,14929439 0,16204332 ! phospholipid biosynthetic process GO:0008654 42 41 0,000 0,14929439 0,16194795 ! leukocyte mediated immunity GO:0002443 41 41 0,000 0,14929439 0,16185268 ! regulation of Ras GTPase activity GO:0032318 41 41 0,000 0,14929439 0,16175753 ! monosaccharide catabolic process GO:0046365 41 41 0,000 0,14929439 0,16166249 ! respiratory electron transport chain GO:0022904 43 42 0,000 0,15265293 0,1652022 ! regulation of cyclic nucleotide metabolic process GO:0030799 42 42 0,000 0,15265293 0,16510525 ! cytosolic calcium ion homeostasis GO:0051480 42 42 0,000 0,15265293 0,16500842 ! development of primary sexual characteristics GO:0045137 42 42 0,000 0,15265293 0,1649117 ! negative regulation of ligase activity GO:0051352 43 42 0,000 0,15265293 0,16481509 GO:0051444|negative regulation of ubiquitin-protein ligase activity, GO:0051436|negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle, ! response to protein stimulus GO:0051789 42 42 0,000 0,15265293 0,16471859 ! forebrain development GO:0030900 43 42 0,000 0,15265293 0,16462221 ! one-carbon metabolic process GO:0006730 42 42 0,000 0,15265293 0,16452594 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 42 42 0,000 0,15265293 0,16442978 ! reproductive structure development GO:0048608 43 43 0,000 0,1559987 0,16793552 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 43 43 0,000 0,1559987 0,16783748 ! alcohol catabolic process GO:0046164 43 43 0,000 0,1559987 0,16773956 ! homeostasis of number of cells GO:0048872 44 43 0,000 0,1559987 0,16764175 ! regulation of nucleotide metabolic process GO:0006140 43 43 0,000 0,1559987 0,16754406 ! humoral immune response GO:0006959 44 44 0,000 0,15933175 0,17102412 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 45 44 0,000 0,15933175 0,17092457 ! mRNA transport GO:0051028 44 44 0,000 0,15933175 0,17082514 ! negative regulation of organelle organization GO:0010639 45 44 0,000 0,15933175 0,17072582 ! positive regulation of lymphocyte activation GO:0051251 44 44 0,000 0,15933175 0,17062662 ! amine biosynthetic process GO:0009309 46 45 0,000 0,16265212 0,17408121 ! regulation of actin cytoskeleton organization GO:0032956 46 45 0,000 0,16265212 0,17398018 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 46 45 0,000 0,16265212 0,17387926 ! steroid biosynthetic process GO:0006694 46 45 0,000 0,16265212 0,17377846 ! protein processing GO:0016485 45 45 0,000 0,16265212 0,17367778 ! regulation of actin filament-based process GO:0032970 47 46 0,000 0,16595985 0,17710713 ! cyclic-nucleotide-mediated signaling GO:0019935 46 46 0,000 0,16595985 0,17700464 ! tube morphogenesis GO:0035239 47 46 0,000 0,16595985 0,17690226 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 47 46 0,000 0,16595985 0,17680001 ! transcription initiation from RNA polymerase II promoter GO:0006367 46 46 0,000 0,16595985 0,17669787 ! positive regulation of ligase activity GO:0051351 47 46 0,000 0,16595985 0,17659585 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 47 47 0,000 0,16925501 0,17999826 ! regulation of blood pressure GO:0008217 48 47 0,000 0,16925501 0,17989445 ! sex differentiation GO:0007548 47 47 0,000 0,16925501 0,17979077 ! amine transport GO:0015837 47 47 0,000 0,16925501 0,1796872 ! rhythmic process GO:0048511 47 47 0,000 0,16925501 0,17958375 ! calcium ion transport GO:0006816 48 48 0,000 0,17253762 0,18296136 ! actin filament organization GO:0007015 50 48 0,000 0,17253762 0,18285615 ! regulation of ubiquitin-protein ligase activity GO:0051438 49 48 0,000 0,17253762 0,18275106 ! regulation of cell cycle process GO:0010564 50 48 0,000 0,17253762 0,18264609 ! DNA recombination GO:0006310 48 48 0,000 0,17253762 0,18254124 ! divalent metal ion transport GO:0070838 49 49 0,000 0,17580775 0,18589425 ! response to nutrient GO:0007584 49 49 0,000 0,17580775 0,18578766 ! response to bacterium GO:0009617 50 49 0,000 0,17580775 0,18568119 ! regulation of ligase activity GO:0051340 50 49 0,000 0,17580775 0,18557484 ! cofactor biosynthetic process GO:0051188 49 49 0,000 0,17580775 0,18546862 ! positive regulation of cell activation GO:0050867 49 49 0,000 0,17580775 0,18536252 GO:0002696|positive regulation of leukocyte activation, ! regulation of defense response GO:0031347 50 50 0,000 0,17906542 0,1886893 ! negative regulation of transport GO:0051051 51 50 0,000 0,17906542 0,18858147 ! chromatin assembly GO:0031497 50 50 0,000 0,17906542 0,18847377 GO:0006334|nucleosome assembly, ! RNA transport GO:0050658 50 50 0,000 0,17906542 0,1883662 GO:0050657|nucleic acid transport, GO:0051236|establishment of RNA localization, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 50 50 0,000 0,17906542 0,18825874 ! nitrogen compound catabolic process GO:0044270 51 50 0,000 0,17906542 0,18815141 ! transcription initiation GO:0006352 50 50 0,000 0,17906542 0,1880442 ! anatomical structure homeostasis GO:0060249 51 50 0,000 0,17906542 0,18793712 ! biogenic amine metabolic process GO:0006576 52 51 0,000 0,1823107 0,19123427 ! positive regulation of immune response GO:0050778 51 51 0,000 0,1823107 0,1911255 ! rRNA metabolic process GO:0016072 51 51 0,000 0,1823107 0,19101684 GO:0006364|rRNA processing, ! protein-DNA complex assembly GO:0065004 51 51 0,000 0,1823107 0,19090831 ! ATP biosynthetic process GO:0006754 51 51 0,000 0,1823107 0,1907999 ! protein maturation GO:0051604 51 51 0,000 0,1823107 0,19069161 ! RNA localization GO:0006403 52 52 0,000 0,18554362 0,19396307 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 52 52 0,000 0,18554362 0,19385311 ! regulation of GTPase activity GO:0043087 53 52 0,000 0,18554362 0,19374328 ! regulation of body fluid levels GO:0050878 55 52 0,000 0,18554362 0,19363357 ! sodium ion transport GO:0006814 53 53 0,000 0,18876423 0,19688312 ! tRNA metabolic process GO:0006399 53 53 0,000 0,18876423 0,19677176 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 53 53 0,000 0,18876423 0,19666053 ! carbohydrate biosynthetic process GO:0016051 53 53 0,000 0,18876423 0,19654942 ! carbohydrate catabolic process GO:0016052 53 53 0,000 0,18876423 0,19643844 ! hormone metabolic process GO:0042445 55 54 0,000 0,19197257 0,19966448 ! sulfur metabolic process GO:0006790 55 54 0,000 0,19197257 0,19955186 ! nucleosome organization GO:0034728 55 55 0,000 0,1951687 0,20275981 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 55 55 0,000 0,1951687 0,20264558 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! ribonucleoside triphosphate biosynthetic process GO:0009201 56 56 0,000 0,19835265 0,20583554 ! ATP metabolic process GO:0046034 57 57 0,000 0,20152446 0,20900933 ! nucleoside triphosphate biosynthetic process GO:0009142 57 57 0,000 0,20152446 0,20889178 ! innate immune response GO:0045087 58 58 0,000 0,20468419 0,21204776 ! cellular aromatic compound metabolic process GO:0006725 60 59 0,000 0,20783188 0,21518773 ! immune effector process GO:0002252 59 59 0,000 0,20783188 0,2150669 ! potassium ion transport GO:0006813 60 60 0,000 0,21096757 0,21818924 ! negative regulation of cellular protein metabolic process GO:0032269 60 60 0,000 0,21096757 0,21806687 ! protein polymerization GO:0051258 65 60 0,000 0,21096757 0,21794464 ! cellular respiration GO:0045333 62 61 0,000 0,21409131 0,22104777 ! proteasomal protein catabolic process GO:0010498 62 61 0,000 0,21409131 0,22092401 GO:0043161|proteasomal ubiquitin-dependent protein catabolic process, ! positive regulation of cellular protein metabolic process GO:0032270 61 61 0,000 0,21409131 0,22080038 ! purine ribonucleoside triphosphate metabolic process GO:0009205 62 62 0,000 0,21720313 0,22388444 ! di-, tri-valent inorganic cation transport GO:0015674 63 62 0,000 0,21720313 0,22375929 ! regulation of secretion GO:0051046 65 63 0,000 0,22030309 0,22682603 ! ribonucleoside triphosphate metabolic process GO:0009199 63 63 0,000 0,22030309 0,22669938 ! purine nucleoside triphosphate metabolic process GO:0009144 63 63 0,000 0,22030309 0,22657288 ! regulation of cytoskeleton organization GO:0051493 66 64 0,000 0,22339122 0,22962076 ! positive regulation of protein metabolic process GO:0051247 64 64 0,000 0,22339122 0,22949277 ! anion transport GO:0006820 65 65 0,000 0,22646758 0,23252354 ! regulation of hormone levels GO:0010817 66 65 0,000 0,22646758 0,23239407 ! protein amino acid glycosylation GO:0006486 66 66 0,000 0,2295322 0,23540781 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! nucleoside triphosphate metabolic process GO:0009141 66 66 0,000 0,2295322 0,23527689 ! DNA packaging GO:0006323 66 66 0,000 0,2295322 0,2351461 ! polysaccharide metabolic process GO:0005976 69 66 0,000 0,2295322 0,23501547 ! negative regulation of protein metabolic process GO:0051248 66 66 0,000 0,2295322 0,23488498 ! Golgi vesicle transport GO:0048193 67 67 0,000 0,23258512 0,23787702 ! muscle contraction GO:0006936 67 67 0,000 0,23258512 0,23774508 ! purine ribonucleotide biosynthetic process GO:0009152 68 68 0,000 0,2356264 0,24072032 ! chromatin assembly or disassembly GO:0006333 68 68 0,000 0,2356264 0,24058695 ! regulation of translation GO:0006417 69 69 0,000 0,23865606 0,24354547 ! sensory perception of sound GO:0007605 71 69 0,000 0,23865606 0,24341069 GO:0050954|sensory perception of mechanical stimulus, ! carboxylic acid biosynthetic process GO:0046394 70 70 0,000 0,24167416 0,24635259 GO:0016053|organic acid biosynthetic process, ! oxidative phosphorylation GO:0006119 71 71 0,000 0,24468074 0,2492795 ! calcium ion homeostasis GO:0055074 71 71 0,000 0,24468074 0,24914177 GO:0006874|cellular calcium ion homeostasis, ! ribosome biogenesis GO:0042254 71 71 0,000 0,24468074 0,2490042 ! muscle system process GO:0003012 72 72 0,000 0,24767584 0,25191312 ! sensory organ development GO:0007423 72 72 0,000 0,24767584 0,25177417 ! regulation of cytokine production GO:0001817 72 72 0,000 0,24767584 0,25163538 ! electron transport chain GO:0022900 75 74 0,000 0,25363176 0,25754454 ! coenzyme metabolic process GO:0006732 75 74 0,000 0,25363176 0,25740272 ! ribonucleotide biosynthetic process GO:0009260 75 75 0,000 0,25659267 0,26026433 ! response to oxidative stress GO:0006979 76 75 0,000 0,25659267 0,26012117 ! purine ribonucleotide metabolic process GO:0009150 75 75 0,000 0,25659267 0,25997817 ! positive regulation of multicellular organismal process GO:0051240 76 76 0,000 0,25954227 0,2628222 ! cellular metal ion homeostasis GO:0006875 77 77 0,000 0,26248059 0,26565169 ! microtubule-based movement GO:0007018 82 78 0,000 0,26540769 0,26846672 ! metal ion homeostasis GO:0055065 78 78 0,000 0,26540769 0,26831945 ! regulation of immune response GO:0050776 78 78 0,000 0,26540769 0,26817235 ! glycoprotein biosynthetic process GO:0009101 80 80 0,000 0,27122835 0,27390348 ! ribonucleotide metabolic process GO:0009259 83 83 0,000 0,27987615 0,28248179 ! ncRNA processing GO:0034470 83 83 0,000 0,27987615 0,28232717 ! cellular amino acid derivative metabolic process GO:0006575 87 84 0,000 0,28273673 0,28505678 ! nitrogen compound biosynthetic process GO:0044271 86 85 0,000 0,28558636 0,28777237 ! male gamete generation GO:0048232 90 88 0,000 0,29407 0,29615902 GO:0007283|spermatogenesis, ! purine nucleotide biosynthetic process GO:0006164 88 88 0,000 0,29407 0,29599727 ! cellular di-, tri-valent inorganic cation homeostasis GO:0030005 89 89 0,000 0,29687626 0,29865881 ! regulation of Ras protein signal transduction GO:0046578 90 90 0,000 0,29967177 0,30130664 ! brain development GO:0007420 91 90 0,000 0,29967177 0,30114235 ! di-, tri-valent inorganic cation homeostasis GO:0055066 91 91 0,000 0,30245658 0,3037752 ! visual perception GO:0007601 93 92 0,000 0,30523073 0,30639446 GO:0050953|sensory perception of light stimulus, ! energy derivation by oxidation of organic compounds GO:0015980 94 92 0,000 0,30523073 0,30622767 ! regulation of response to stress GO:0080134 97 94 0,000 0,31074718 0,31159252 ! cofactor metabolic process GO:0051186 95 94 0,000 0,31074718 0,31142309 ! endocytosis GO:0006897 99 98 0,000 0,32165382 0,32217826 GO:0010324|membrane invagination, ! glycoprotein metabolic process GO:0009100 99 98 0,000 0,32165382 0,32200326 ! regulation of system process GO:0044057 98 98 0,000 0,32165382 0,32182845 ! anti-apoptosis GO:0006916 100 99 0,000 0,32435441 0,32435441