pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6657-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 4,000 5,932E-11 1,427E-07 ! phospholipid dephosphorylation GO:0046839 12 5 3,000 4,067E-10 4,892E-07 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 3,000 1,217E-09 9,762E-07 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 4,000 1,432E-09 8,615E-07 ! negative regulation of focal adhesion formation GO:0051895 20 7 3,000 2,833E-09 1,363E-06 ! regulation of focal adhesion formation GO:0051893 22 8 3,000 5,654E-09 2,267E-06 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 3,000 1,688E-08 5,803E-06 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 5,000 2,205E-08 6,63E-06 ! lipid modification GO:0030258 97 57 5,000 2,205E-08 5,893E-06 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 3,000 2,647E-08 6,368E-06 GO:0010812|negative regulation of cell-substrate adhesion, ! endothelial cell migration GO:0043542 28 17 3,000 1,882E-07 4,117E-05 ! inositol metabolic process GO:0006020 28 17 3,000 1,882E-07 3,774E-05 ! cardiac muscle tissue development GO:0048738 31 17 3,000 1,882E-07 3,484E-05 ! myoblast cell fate commitment GO:0048625 16 6 2,000 5,48E-07 9,419E-05 ! regulation of cell-matrix adhesion GO:0001952 78 23 3,000 6,905E-07 1,108E-04 GO:0010810|regulation of cell-substrate adhesion, ! positive regulation of insulin secretion GO:0032024 15 8 2,000 1,528E-06 2,297E-04 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 2,000 1,528E-06 2,162E-04 ! negative regulation of protein kinase cascade GO:0010741 68 30 3,000 2,102E-06 2,81E-04 ! phosphoinositide metabolic process GO:0030384 128 72 4,000 2,837E-06 3,592E-04 ! negative regulation of cell adhesion GO:0007162 81 35 3,000 3,97E-06 4,776E-04 ! positive regulation of peptide secretion GO:0002793 22 11 2,000 4,472E-06 5,123E-04 ! regulation of protein stability GO:0031647 73 37 3,000 4,985E-06 5,451E-04 ! carbohydrate homeostasis GO:0033500 53 38 3,000 5,558E-06 5,814E-04 GO:0042593|glucose homeostasis, ! regulation of hormone metabolic process GO:0032350 26 12 2,000 5,949E-06 5,964E-04 ! polyol metabolic process GO:0019751 66 41 3,000 7,572E-06 7,287E-04 ! regulation of cell adhesion GO:0030155 212 89 4,000 8,079E-06 7,476E-04 ! negative regulation of cell migration GO:0030336 115 46 3,000 1,206E-05 1,075E-03 ! epithelial to mesenchymal transition GO:0001837 28 15 2,000 1,222E-05 1,05E-03 ! skeletal muscle tissue development GO:0007519 186 99 4,000 1,359E-05 1,128E-03 GO:0060538|skeletal muscle organ development, ! cell cycle arrest GO:0007050 213 100 4,000 1,427E-05 1,145E-03 ! myoblast differentiation GO:0045445 45 17 2,000 1,818E-05 1,411E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 2,000 1,818E-05 1,367E-03 ! negative regulation of cell motion GO:0051271 134 55 3,000 2,468E-05 1,8E-03 ! positive regulation of hormone secretion GO:0046887 32 19 2,000 2,58E-05 1,826E-03 ! skeletal muscle fiber development GO:0048741 111 56 3,000 2,652E-05 1,823E-03 ! muscle fiber development GO:0048747 112 57 3,000 2,845E-05 1,902E-03 ! positive regulation of cell migration GO:0030335 126 57 3,000 2,845E-05 1,85E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 2,000 3,028E-05 1,917E-03 ! pancreas development GO:0031016 35 20 2,000 3,028E-05 1,868E-03 ! protein amino acid autophosphorylation GO:0046777 141 60 3,000 3,488E-05 2,098E-03 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 2,000 4,073E-05 2,39E-03 ! positive regulation of cell motion GO:0051272 146 64 3,000 4,503E-05 2,579E-03 ! protein tetramerization GO:0051262 52 24 2,000 5,329E-05 2,982E-03 ! regulation of insulin secretion GO:0050796 37 25 2,000 6,043E-05 3,304E-03 ! insulin receptor signaling pathway GO:0008286 64 26 2,000 6,816E-05 3,644E-03 ! fat cell differentiation GO:0045444 50 27 2,000 7,651E-05 4,002E-03 ! negative regulation of bone resorption GO:0045779 10 5 1,000 9,175E-05 4,697E-03 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 1,000 9,175E-05 4,599E-03 ! positive regulation of glycolysis GO:0045821 14 5 1,000 9,175E-05 4,505E-03 ! anagen GO:0042640 6 5 1,000 9,175E-05 4,415E-03 ! positive regulation of filopodium assembly GO:0051491 14 5 1,000 9,175E-05 4,329E-03 GO:0051489|regulation of filopodium assembly, ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 9,175E-05 4,245E-03 ! decidualization GO:0046697 11 5 1,000 9,175E-05 4,165E-03 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 1,000 9,175E-05 4,088E-03 ! regulation of peptide secretion GO:0002791 47 29 2,000 9,515E-05 4,163E-03 ! protein oligomerization GO:0051259 139 78 3,000 9,784E-05 4,204E-03 ! ensheathment of neurons GO:0007272 57 30 2,000 1,055E-04 4,453E-03 GO:0008366|axon ensheathment, ! activation of MAPKKK activity GO:0000185 12 6 1,000 1,374E-04 5,698E-03 ! positive regulation of neuroblast proliferation GO:0002052 13 6 1,000 1,374E-04 5,601E-03 ! male sex determination GO:0030238 15 6 1,000 1,374E-04 5,508E-03 ! hair follicle maturation GO:0048820 7 6 1,000 1,374E-04 5,418E-03 ! negative regulation of neuroblast proliferation GO:0007406 21 6 1,000 1,374E-04 5,33E-03 ! maternal placenta development GO:0001893 12 6 1,000 1,374E-04 5,246E-03 ! androgen receptor signaling pathway GO:0030521 74 36 2,000 1,831E-04 6,883E-03 ! regulation of helicase activity GO:0051095 15 7 1,000 1,919E-04 7,104E-03 ! N-terminal protein amino acid acetylation GO:0006474 13 7 1,000 1,919E-04 6,996E-03 ! mRNA stabilization GO:0048255 18 7 1,000 1,919E-04 6,892E-03 GO:0043489|RNA stabilization, ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 1,000 1,919E-04 6,79E-03 ! G1 DNA damage checkpoint GO:0031571 21 7 1,000 1,919E-04 6,692E-03 ! B cell lineage commitment GO:0002326 21 7 1,000 1,919E-04 6,596E-03 ! T cell lineage commitment GO:0002360 16 7 1,000 1,919E-04 6,504E-03 ! response to tumor cell GO:0002347 13 7 1,000 1,919E-04 6,413E-03 ! regulation of respiratory burst GO:0060263 11 7 1,000 1,919E-04 6,325E-03 ! positive regulation of MAP kinase activity GO:0043406 160 93 3,000 1,934E-04 6,288E-03 ! cellular response to insulin stimulus GO:0032869 82 37 2,000 1,988E-04 6,377E-03 ! regulation of action potential in neuron GO:0019228 73 39 2,000 2,328E-04 7,37E-03 ! regulation of hormone secretion GO:0046883 62 40 2,000 2,511E-04 7,846E-03 ! mesenchymal cell development GO:0014031 87 40 2,000 2,511E-04 7,746E-03 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 2,554E-04 7,778E-03 ! T-helper 1 type immune response GO:0042088 12 8 1,000 2,554E-04 7,681E-03 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 2,554E-04 7,586E-03 ! ER overload response GO:0006983 12 8 1,000 2,554E-04 7,493E-03 ! positive regulation of endothelial cell migration GO:0010595 19 8 1,000 2,554E-04 7,403E-03 ! regulation of vascular permeability GO:0043114 12 8 1,000 2,554E-04 7,315E-03 ! regulation of fat cell differentiation GO:0045598 15 8 1,000 2,554E-04 7,229E-03 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 1,000 2,554E-04 7,145E-03 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 1,000 2,554E-04 7,063E-03 ! regulation of epithelial cell proliferation GO:0050678 111 43 2,000 3,116E-04 8,519E-03 ! regulation of developmental growth GO:0048638 15 9 1,000 3,277E-04 8,859E-03 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 3,277E-04 8,76E-03 ! induction of positive chemotaxis GO:0050930 15 9 1,000 3,277E-04 8,664E-03 ! regulation of glycolysis GO:0006110 21 9 1,000 3,277E-04 8,57E-03 ! keratinocyte proliferation GO:0043616 14 9 1,000 3,277E-04 8,478E-03 ! microtubule bundle formation GO:0001578 21 9 1,000 3,277E-04 8,387E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 1,000 3,277E-04 8,299E-03 ! motor axon guidance GO:0008045 16 9 1,000 3,277E-04 8,213E-03 ! protein heterooligomerization GO:0051291 16 9 1,000 3,277E-04 8,128E-03 ! JAK-STAT cascade GO:0007259 71 44 2,000 3,336E-04 8,191E-03 ! regulation of gene-specific transcription GO:0032583 96 46 2,000 3,807E-04 9,253E-03 ! response to insulin stimulus GO:0032868 95 46 2,000 3,807E-04 9,16E-03 ! lung alveolus development GO:0048286 26 10 1,000 4,088E-04 9,738E-03 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 1,000 4,088E-04 9,643E-03 ! regulation of bone resorption GO:0045124 25 10 1,000 4,088E-04 9,549E-03 ! positive regulation of leukocyte migration GO:0002687 25 10 1,000 4,088E-04 9,457E-03 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 1,000 4,088E-04 9,367E-03 GO:0043470|regulation of carbohydrate catabolic process, ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 1,000 4,088E-04 9,279E-03 ! localization within membrane GO:0051668 20 10 1,000 4,088E-04 9,192E-03 ! regulation of action potential GO:0001508 95 49 2,000 4,59E-04 0,01022651 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 1,000 4,986E-04 0,01100687 ! blood vessel remodeling GO:0001974 29 11 1,000 4,986E-04 0,01090681 ! positive regulation of endothelial cell proliferation GO:0001938 22 11 1,000 4,986E-04 0,01080855 ! peptide or protein amino-terminal blocking GO:0018409 21 11 1,000 4,986E-04 0,01071204 ! regulation of intracellular pH GO:0051453 19 11 1,000 4,986E-04 0,01061725 ! substrate-bound cell migration GO:0006929 13 11 1,000 4,986E-04 0,01052411 ! regulation of leukocyte migration GO:0002685 26 11 1,000 4,986E-04 0,0104326 ! regulation of embryonic development GO:0045995 27 11 1,000 4,986E-04 0,01034266 ! response to UV GO:0009411 104 53 2,000 5,785E-04 0,01189727 ! positive regulation of cellular catabolic process GO:0031331 31 12 1,000 5,972E-04 0,01217658 ! virus-host interaction GO:0019048 29 12 1,000 5,972E-04 0,01207425 ! regulation of positive chemotaxis GO:0050926 19 12 1,000 5,972E-04 0,01197363 GO:0050927|positive regulation of positive chemotaxis, ! regulation of cell projection assembly GO:0060491 30 12 1,000 5,972E-04 0,01187468 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 1,000 5,972E-04 0,01177734 ! histone acetylation GO:0016573 26 12 1,000 5,972E-04 0,01168159 ! peptidyl-lysine modification GO:0018205 21 12 1,000 5,972E-04 0,01158739 ! negative regulation of mast cell proliferation GO:0070667 23 12 1,000 5,972E-04 0,01149469 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 1,000 5,972E-04 0,01140346 ! regulation of DNA replication GO:0006275 101 56 2,000 6,801E-04 0,01288403 ! response to X-ray GO:0010165 25 13 1,000 7,044E-04 0,01323987 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 1,000 7,044E-04 0,01313724 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of cellular pH GO:0030641 22 13 1,000 7,044E-04 0,01303618 ! regulation of monooxygenase activity GO:0032768 33 13 1,000 7,044E-04 0,01293667 ! regulation of mRNA stability GO:0043488 31 13 1,000 7,044E-04 0,01283866 ! positive regulation of secretion GO:0051047 95 59 2,000 7,923E-04 0,01433318 ! N-terminal protein amino acid modification GO:0031365 27 14 1,000 8,201E-04 0,01472556 ! actin cytoskeleton reorganization GO:0031532 33 14 1,000 8,201E-04 0,01461648 ! embryo implantation GO:0007566 30 14 1,000 8,201E-04 0,014509 ! response to gamma radiation GO:0010332 28 14 1,000 8,201E-04 0,0144031 ! regulation of RNA stability GO:0043487 32 14 1,000 8,201E-04 0,01429873 ! release of cytochrome c from mitochondria GO:0001836 30 14 1,000 8,201E-04 0,01419586 ! response to peptide hormone stimulus GO:0043434 122 61 2,000 8,733E-04 0,01500826 ! negative regulation of bone remodeling GO:0046851 33 15 1,000 9,444E-04 0,01611542 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 1,000 9,444E-04 0,01600193 ! G1/S transition checkpoint GO:0031575 40 15 1,000 9,444E-04 0,01589002 ! steroid hormone receptor signaling pathway GO:0030518 129 63 2,000 9,594E-04 0,01602919 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 1,077E-03 0,01787397 ! activation of MAPKK activity GO:0000186 35 16 1,000 1,077E-03 0,01775154 ! negative regulation of microtubule depolymerization GO:0007026 46 16 1,000 1,077E-03 0,01763078 GO:0031114|regulation of microtubule depolymerization, ! positive regulation of protein import into nucleus GO:0042307 30 16 1,000 1,077E-03 0,01751166 ! negative regulation of tissue remodeling GO:0034104 36 16 1,000 1,077E-03 0,01739413 ! negative regulation of leukocyte proliferation GO:0070664 31 16 1,000 1,077E-03 0,01727817 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 1,077E-03 0,01716374 ! negative regulation of protein kinase activity GO:0006469 130 67 2,000 1,147E-03 0,01815829 ! lung development GO:0030324 144 67 2,000 1,147E-03 0,01803961 ! negative regulation of kinase activity GO:0033673 131 68 2,000 1,197E-03 0,01870843 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 2,000 1,197E-03 0,01858773 ! negative regulation of homeostatic process GO:0032845 33 17 1,000 1,218E-03 0,01879138 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 1,000 1,218E-03 0,01867169 ! respiratory tube development GO:0030323 150 70 2,000 1,302E-03 0,01982977 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 1,368E-03 0,02070024 ! centrosome cycle GO:0007098 25 18 1,000 1,368E-03 0,02057087 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 1,000 1,368E-03 0,0204431 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 1,000 1,368E-03 0,0203169 ! regulation of caspase activity GO:0043281 122 72 2,000 1,413E-03 0,02085014 ! negative regulation of transferase activity GO:0051348 140 72 2,000 1,413E-03 0,020723 ! respiratory system development GO:0060541 153 72 2,000 1,413E-03 0,02059741 ! lipid phosphorylation GO:0046834 35 19 1,000 1,526E-03 0,02211598 ! neuromuscular junction development GO:0007528 34 19 1,000 1,526E-03 0,02198355 ! regulation of endothelial cell migration GO:0010594 44 19 1,000 1,526E-03 0,02185269 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 1,000 1,526E-03 0,02172339 ! exocytosis GO:0006887 133 74 2,000 1,529E-03 0,02163391 ! regulation of endopeptidase activity GO:0052548 125 74 2,000 1,529E-03 0,0215074 ! protein amino acid acetylation GO:0006473 39 20 1,000 1,692E-03 0,02366903 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 1,000 1,692E-03 0,02353221 ! regulation of carbohydrate metabolic process GO:0006109 38 20 1,000 1,692E-03 0,02339697 GO:0010675|regulation of cellular carbohydrate metabolic process, ! apoptotic mitochondrial changes GO:0008637 41 20 1,000 1,692E-03 0,02326328 ! cellular response to starvation GO:0009267 33 20 1,000 1,692E-03 0,0231311 ! fatty acid beta-oxidation GO:0006635 34 20 1,000 1,692E-03 0,02300041 ! negative regulation of T cell activation GO:0050868 40 20 1,000 1,692E-03 0,0228712 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 1,000 1,692E-03 0,02274343 ! regulation of peptidase activity GO:0052547 134 79 2,000 1,844E-03 0,02465257 ! cell aging GO:0007569 44 21 1,000 1,866E-03 0,02481038 ! positive regulation of locomotion GO:0040017 39 21 1,000 1,866E-03 0,02467406 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! vitamin A metabolic process GO:0006776 33 21 1,000 1,866E-03 0,02453923 ! muscle cell differentiation GO:0042692 159 80 2,000 1,912E-03 0,02500124 ! response to hypoxia GO:0001666 171 81 2,000 1,981E-03 0,0257658 ! regulation of chemotaxis GO:0050920 40 22 1,000 2,049E-03 0,02650509 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 1,000 2,049E-03 0,02636335 ! vesicle docking during exocytosis GO:0006904 41 22 1,000 2,049E-03 0,02622312 ! positive regulation of intracellular transport GO:0032388 37 22 1,000 2,049E-03 0,02608438 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 1,000 2,049E-03 0,02594709 ! cellular response to hormone stimulus GO:0032870 167 82 2,000 2,052E-03 0,02584726 ! response to oxygen levels GO:0070482 176 83 2,000 2,124E-03 0,02661832 ! positive regulation of DNA replication GO:0045740 43 23 1,000 2,24E-03 0,02792102 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 2,24E-03 0,0277771 ! sex determination GO:0007530 47 23 1,000 2,24E-03 0,02763465 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 1,000 2,24E-03 0,02749366 ! fatty acid transport GO:0015908 44 23 1,000 2,24E-03 0,0273541 ! protein import into nucleus, translocation GO:0000060 46 24 1,000 2,438E-03 0,02963125 ! regulation of cellular catabolic process GO:0031329 52 24 1,000 2,438E-03 0,02948235 ! vesicle docking GO:0048278 47 24 1,000 2,438E-03 0,02933493 ! regulation of behavior GO:0050795 43 24 1,000 2,438E-03 0,02918899 ! regulation of oxidoreductase activity GO:0051341 46 24 1,000 2,438E-03 0,02904449 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 1,000 2,645E-03 0,0313523 ! myelination GO:0042552 45 25 1,000 2,645E-03 0,03119861 ! vasculogenesis GO:0001570 46 25 1,000 2,645E-03 0,03104643 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 1,000 2,645E-03 0,03089571 ! negative regulation of DNA replication GO:0008156 42 25 1,000 2,645E-03 0,03074646 ! response to starvation GO:0042594 42 25 1,000 2,645E-03 0,03059864 ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 2,645E-03 0,03045224 ! negative regulation of cell development GO:0010721 73 25 1,000 2,645E-03 0,03030722 GO:0050768|negative regulation of neurogenesis, ! interaction with host GO:0051701 62 25 1,000 2,645E-03 0,03016359 ! somitogenesis GO:0001756 43 25 1,000 2,645E-03 0,03002131 ! cellular response to nutrient levels GO:0031669 41 25 1,000 2,645E-03 0,02988036 ! molting cycle process GO:0022404 50 26 1,000 2,86E-03 0,03215527 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! regulation of transcription factor import into nucleus GO:0042990 54 26 1,000 2,86E-03 0,03200571 ! microtubule organizing center organization GO:0031023 39 26 1,000 2,86E-03 0,03185754 GO:0051297|centrosome organization, ! regulation of endothelial cell proliferation GO:0001936 57 26 1,000 2,86E-03 0,03171073 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 1,000 2,86E-03 0,03156527 ! regulation of membrane potential GO:0042391 164 93 2,000 2,935E-03 0,03224319 ! regulation of fibroblast proliferation GO:0048145 52 27 1,000 3,083E-03 0,03371364 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 1,000 3,083E-03 0,03356109 ! positive regulation of cell projection organization GO:0031346 58 27 1,000 3,083E-03 0,03340991 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 1,000 3,083E-03 0,03326009 ! protein amino acid acylation GO:0043543 55 27 1,000 3,083E-03 0,03311161 ! mitochondrial membrane organization GO:0007006 57 27 1,000 3,083E-03 0,03296444 ! base-excision repair GO:0006284 41 27 1,000 3,083E-03 0,03281858 ! fat-soluble vitamin metabolic process GO:0006775 40 27 1,000 3,083E-03 0,03267401 ! negative regulation of lymphocyte activation GO:0051250 53 27 1,000 3,083E-03 0,0325307 ! interphase of mitotic cell cycle GO:0051329 209 95 2,000 3,117E-03 0,03274638 ! regulation of DNA metabolic process GO:0051052 178 97 2,000 3,305E-03 0,03457786 ! dendrite development GO:0016358 59 28 1,000 3,313E-03 0,03450959 ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 3,313E-03 0,03436084 ! peptidyl-tyrosine modification GO:0018212 50 28 1,000 3,313E-03 0,03421337 ! lipid oxidation GO:0034440 43 28 1,000 3,313E-03 0,03406715 GO:0019395|fatty acid oxidation, ! response to virus GO:0009615 160 98 2,000 3,402E-03 0,0348344 ! interphase GO:0051325 213 98 2,000 3,402E-03 0,03468679 ! regulation of pH GO:0006885 43 29 1,000 3,552E-03 0,03605592 ! cellular response to extracellular stimulus GO:0031668 48 29 1,000 3,552E-03 0,03590442 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 1,000 3,552E-03 0,0357542 ! membrane docking GO:0022406 61 30 1,000 3,798E-03 0,03807291 ! negative regulation of leukocyte activation GO:0002695 56 30 1,000 3,798E-03 0,03791493 ! fatty acid catabolic process GO:0009062 48 31 1,000 4,052E-03 0,04028237 ! response to ionizing radiation GO:0010212 65 32 1,000 4,313E-03 0,04270634 ! regulation of protein import into nucleus GO:0042306 63 32 1,000 4,313E-03 0,04253132 ! peripheral nervous system development GO:0007422 64 32 1,000 4,313E-03 0,04235772 ! positive regulation of catabolic process GO:0009896 64 32 1,000 4,313E-03 0,04218553 ! DNA damage checkpoint GO:0000077 71 33 1,000 4,582E-03 0,04463687 ! positive regulation of gene-specific transcription GO:0043193 65 33 1,000 4,582E-03 0,04445688 ! positive regulation of neurogenesis GO:0050769 67 33 1,000 4,582E-03 0,04427834 ! placenta development GO:0001890 53 34 1,000 4,859E-03 0,04676485 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 1,000 4,859E-03 0,04657853 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 1,000 5,143E-03 0,04910811 ! negative regulation of DNA metabolic process GO:0051053 61 35 1,000 5,143E-03 0,04891401 ! negative regulation of hydrolase activity GO:0051346 62 35 1,000 5,143E-03 0,04872144 ! calcium-mediated signaling GO:0019722 62 35 1,000 5,143E-03 0,04853037 ! regulation of microtubule-based process GO:0032886 78 35 1,000 5,143E-03 0,0483408 ! positive regulation of cell development GO:0010720 80 36 1,000 5,435E-03 0,05088439 ! DNA integrity checkpoint GO:0031570 75 36 1,000 5,435E-03 0,05068717 ! negative regulation of cell activation GO:0050866 65 36 1,000 5,435E-03 0,05049146 ! tissue remodeling GO:0048771 76 37 1,000 5,735E-03 0,05306628 ! monovalent inorganic cation homeostasis GO:0055067 58 37 1,000 5,735E-03 0,05286296 ! positive regulation of DNA metabolic process GO:0051054 72 38 1,000 6,041E-03 0,05547694 ! mitotic cell cycle checkpoint GO:0007093 76 38 1,000 6,041E-03 0,055266 ! isoprenoid metabolic process GO:0006720 66 38 1,000 6,041E-03 0,05505666 ! mammary gland development GO:0030879 86 39 1,000 6,355E-03 0,05769946 ! segmentation GO:0035282 67 39 1,000 6,355E-03 0,05748255 ! regulation of T cell proliferation GO:0042129 71 41 1,000 7,005E-03 0,06312255 ! T cell differentiation GO:0030217 81 41 1,000 7,005E-03 0,06288701 ! regulation of T cell differentiation GO:0045580 70 41 1,000 7,005E-03 0,06265323 ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 7,341E-03 0,06541282 GO:0090047|positive regulation of transcription regulator activity, ! negative regulation of protein complex disassembly GO:0043242 101 42 1,000 7,341E-03 0,06517144 ! monocarboxylic acid transport GO:0015718 85 42 1,000 7,341E-03 0,06493184 ! regulation of intracellular protein transport GO:0033157 80 42 1,000 7,341E-03 0,06469399 ! glucose transport GO:0015758 65 43 1,000 7,683E-03 0,06746871 ! positive regulation of response to external stimulus GO:0032103 77 43 1,000 7,683E-03 0,06722337 ! hexose transport GO:0008645 67 44 1,000 8,033E-03 0,07003082 GO:0015749|monosaccharide transport, ! double-strand break repair GO:0006302 81 44 1,000 8,033E-03 0,069778 ! B cell differentiation GO:0030183 107 44 1,000 8,033E-03 0,069527 ! developmental growth GO:0048589 82 44 1,000 8,033E-03 0,0692778 ! induction of apoptosis by intracellular signals GO:0008629 93 45 1,000 8,391E-03 0,07209854 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 1,000 8,755E-03 0,07495932 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 1,000 8,755E-03 0,07469351 ! positive regulation of protein transport GO:0051222 72 46 1,000 8,755E-03 0,07442957 ! positive regulation of DNA binding GO:0043388 73 47 1,000 9,126E-03 0,07731104 ! vascular process in circulatory system GO:0003018 80 47 1,000 9,126E-03 0,07703977 ! protein homooligomerization GO:0051260 76 47 1,000 9,126E-03 0,0767704 ! positive regulation of cell cycle GO:0045787 89 48 1,000 9,504E-03 0,0796717 ! mitochondrial transport GO:0006839 82 48 1,000 9,504E-03 0,07939507 ! Notch signaling pathway GO:0007219 96 48 1,000 9,504E-03 0,07912034 ! morphogenesis of embryonic epithelium GO:0016331 91 48 1,000 9,504E-03 0,07884751 ! activation of caspase activity GO:0006919 84 48 1,000 9,504E-03 0,07857656 ! regulation of lymphocyte differentiation GO:0045619 81 48 1,000 9,504E-03 0,07830746 ! regulation of mast cell proliferation GO:0070666 81 48 1,000 9,504E-03 0,0780402 ! regulation of protein complex disassembly GO:0043244 113 49 1,000 9,889E-03 0,08092446 ! regulation of cell projection organization GO:0031344 121 50 1,000 0,01028024 0,08384498 ! histone modification GO:0016570 91 50 1,000 0,01028024 0,08356172 ! negative regulation of immune system process GO:0002683 95 50 1,000 0,01028024 0,08328036 ! positive regulation of binding GO:0051099 78 51 1,000 0,01067876 0,08621845 ! regulation of leukocyte proliferation GO:0070663 88 51 1,000 0,01067876 0,0859301 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of cell shape GO:0008360 125 51 1,000 0,01067876 0,08564367 ! regulation of angiogenesis GO:0045765 114 52 1,000 0,01108403 0,0885986 ! positive regulation of growth GO:0045927 90 52 1,000 0,01108403 0,08830523 ! covalent chromatin modification GO:0016569 101 52 1,000 0,01108403 0,0880138 ! synapse organization GO:0050808 85 52 1,000 0,01108403 0,08772428 ! regulation of neuron apoptosis GO:0043523 100 53 1,000 0,01149601 0,09068657 ! activation of phospholipase C activity GO:0007202 103 54 1,000 0,01191466 0,09368191 GO:0010863|positive regulation of phospholipase C activity, ! negative regulation of cytoskeleton organization GO:0051494 124 54 1,000 0,01191466 0,09337676 ! positive regulation of caspase activity GO:0043280 95 55 1,000 0,01233992 0,09639564 GO:0010952|positive regulation of peptidase activity, ! positive regulation of phospholipase activity GO:0010518 104 55 1,000 0,01233992 0,09608368 ! aging GO:0007568 103 55 1,000 0,01233992 0,09577374 ! heart morphogenesis GO:0003007 97 55 1,000 0,01233992 0,09546578 ! nucleotide-excision repair GO:0006289 83 56 1,000 0,01277177 0,09849 ! regulation of bone remodeling GO:0046850 137 57 1,000 0,01321015 0,10154513 ! regulation of phospholipase activity GO:0010517 106 57 1,000 0,01321015 0,10122174 ! regulation of intracellular transport GO:0032386 101 57 1,000 0,01321015 0,1009004 ! regulation of tissue remodeling GO:0034103 140 58 1,000 0,01365503 0,10396833 ! positive regulation of lipase activity GO:0060193 108 58 1,000 0,01365503 0,10364035 ! DNA damage response, signal transduction GO:0042770 128 60 1,000 0,01456408 0,11019237 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,01518174 0,11450552 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,01518174 0,11414769 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,01518174 0,11379209 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,01518174 0,11343869 ! neuron fate determination GO:0048664 7 5 0,000 0,01518174 0,11308749 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01518174 0,11273846 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,01518174 0,11239157 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,01518174 0,11204681 ! polyol transport GO:0015791 12 5 0,000 0,01518174 0,11170416 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,01518174 0,1113636 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,01518174 0,11102511 ! response to superoxide GO:0000303 10 5 0,000 0,01518174 0,11068867 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,01518174 0,11035426 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,01518174 0,11002187 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,01518174 0,10969147 ! female meiosis GO:0007143 7 5 0,000 0,01518174 0,10936305 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,01518174 0,1090366 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,01518174 0,10871208 ! cobalt ion transport GO:0006824 11 5 0,000 0,01518174 0,10838949 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,01518174 0,10806882 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,01518174 0,10775003 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,01518174 0,10743312 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,01518174 0,10711806 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,01518174 0,10680485 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,01518174 0,10649347 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,01518174 0,10618389 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,01518174 0,10587611 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,01518174 0,10557011 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01518174 0,10526588 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,01518174 0,10496339 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,01518174 0,10466263 ! negative chemotaxis GO:0050919 14 5 0,000 0,01518174 0,1043636 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,01518174 0,10406627 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,01518174 0,10377062 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,01518174 0,10347666 ! behavioral response to pain GO:0048266 9 5 0,000 0,01518174 0,10318435 ! clathrin coat assembly GO:0048268 14 5 0,000 0,01518174 0,10289369 ! Notch receptor processing GO:0007220 8 5 0,000 0,01518174 0,10260466 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01518174 0,10231725 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,01518174 0,10203145 ! micturition GO:0060073 9 5 0,000 0,01518174 0,10174724 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,01518174 0,10146461 ! copulation GO:0007620 9 5 0,000 0,01518174 0,10118354 ! glial cell fate commitment GO:0021781 13 5 0,000 0,01518174 0,10090403 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,01518174 0,10062606 ! spermidine metabolic process GO:0008216 7 5 0,000 0,01518174 0,10034961 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,01518174 0,10007468 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,01518174 0,09980126 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,01518174 0,09952932 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,01518174 0,09925886 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,01518174 0,09898986 ! grooming behavior GO:0007625 6 5 0,000 0,01518174 0,09872232 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,01518174 0,09845623 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,01518174 0,09819156 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01518174 0,09792831 ! response to protozoan GO:0001562 10 5 0,000 0,01518174 0,09766647 ! lymph vessel development GO:0001945 10 5 0,000 0,01518174 0,09740603 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,01518174 0,09714697 ! endochondral ossification GO:0001958 16 5 0,000 0,01518174 0,09688928 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,01518174 0,09663296 ! parathyroid gland development GO:0060017 13 5 0,000 0,01518174 0,09637799 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,01518174 0,09612437 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,01518174 0,09587207 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,01518174 0,0956211 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,01518174 0,09537143 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,01518174 0,09512307 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,01518174 0,094876 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,01518174 0,09463021 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,01518174 0,09438568 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,01518174 0,09414242 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,01518174 0,09390041 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,01518174 0,09365964 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,01518174 0,0934201 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,01518174 0,09318178 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,01518174 0,09294468 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,01518174 0,09270878 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,01518174 0,09247407 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 0,01518174 0,09224055 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,01518174 0,09200821 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,01518174 0,09177703 ! histidine catabolic process GO:0006548 6 5 0,000 0,01518174 0,09154702 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,01518174 0,09131815 ! microvillus organization GO:0032528 7 5 0,000 0,01518174 0,09109042 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 0,01518174 0,09086383 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,01518174 0,09063836 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,01518174 0,09041401 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,01518174 0,09019076 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,01518174 0,08996862 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,01518174 0,08974757 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,01518174 0,0895276 ! polyol catabolic process GO:0046174 7 5 0,000 0,01518174 0,0893087 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,01518174 0,08909088 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,01518174 0,08887411 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,01518174 0,0886584 ! muscle cell migration GO:0014812 8 5 0,000 0,01518174 0,08844373 ! mitochondrial fission GO:0000266 8 5 0,000 0,01518174 0,0882301 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,01518174 0,08801749 ! mRNA transcription GO:0009299 9 5 0,000 0,01518174 0,08780591 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,01518174 0,08759535 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,01518174 0,08738579 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,01518174 0,08717723 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,01518174 0,08696967 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,01518174 0,08676309 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,01518174 0,08655749 ! response to food GO:0032094 6 5 0,000 0,01518174 0,08635286 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,01518174 0,0861492 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,01518174 0,08594649 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,01518174 0,08574474 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01518174 0,08554393 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,01518174 0,08534406 ! forebrain neuron development GO:0021884 13 5 0,000 0,01518174 0,08514513 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,01518174 0,08494712 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,01518174 0,08475002 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,01518174 0,08455384 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01518174 0,08435857 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,01518174 0,08416419 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,01518174 0,08397071 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01518174 0,08377812 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,01518174 0,08358641 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,01518174 0,08339557 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,01518174 0,0832056 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,01518174 0,0830165 ! basic amino acid transport GO:0015802 11 5 0,000 0,01518174 0,08282825 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,01518174 0,08264086 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,01518174 0,08245431 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01518174 0,0822686 ! depyrimidination GO:0045008 10 5 0,000 0,01518174 0,08208373 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,01518174 0,08189969 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01518174 0,08171646 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,01518174 0,08153406 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,01518174 0,08135247 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 0,01518174 0,08117169 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,01518174 0,08099171 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01518174 0,08081252 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,01518174 0,08063413 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,01518174 0,08045652 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,01518174 0,08027969 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,01518174 0,08010364 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,01518174 0,07992836 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01518174 0,07975384 ! response to arsenic GO:0046685 10 5 0,000 0,01518174 0,07958009 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,01518174 0,07940709 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,01518174 0,07923484 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,01518174 0,07906333 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,01518174 0,07889257 ! response to cadmium ion GO:0046686 7 5 0,000 0,01518174 0,07872254 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,01518174 0,07855325 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,01518174 0,07838468 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,01518174 0,07821683 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,01518174 0,0780497 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,01518174 0,07788328 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,01518174 0,07771757 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,01518174 0,07755257 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,01518174 0,07738826 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,01518174 0,07722465 ! neural tube patterning GO:0021532 7 5 0,000 0,01518174 0,07706173 ! embryonic cleavage GO:0040016 6 5 0,000 0,01518174 0,07689949 ! peroxisome fission GO:0016559 5 5 0,000 0,01518174 0,07673794 ! histone demethylation GO:0016577 10 5 0,000 0,01518174 0,07657706 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,01518174 0,07641686 ! mitotic recombination GO:0006312 9 5 0,000 0,01518174 0,07625733 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,01518174 0,07609846 ! metaphase plate congression GO:0051310 7 5 0,000 0,01518174 0,07594025 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01518174 0,0757827 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,01518174 0,0756258 ! enteric nervous system development GO:0048484 8 5 0,000 0,01518174 0,07546954 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,01518174 0,07531394 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,01518174 0,07515897 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,01518174 0,07500464 ! muscle cell proliferation GO:0033002 11 5 0,000 0,01518174 0,07485094 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,01518174 0,07469787 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,01518174 0,07454543 ! plasminogen activation GO:0031639 5 5 0,000 0,01518174 0,0743936 ! B cell homeostasis GO:0001782 13 5 0,000 0,01518174 0,0742424 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,01518174 0,0740918 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,01518174 0,07394182 ! metaphase GO:0051323 8 5 0,000 0,01518174 0,07379244 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,01518174 0,07364367 ! cellular response to nutrient GO:0031670 8 5 0,000 0,01518174 0,07349549 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,01518174 0,07334791 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,01518174 0,07320092 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,01518174 0,07305452 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,01518174 0,0729087 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,01518174 0,07276347 ! response to redox state GO:0051775 5 5 0,000 0,01518174 0,07261881 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,01518174 0,07247472 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,01518174 0,07233121 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,01518174 0,07218826 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,01518174 0,07204588 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01518174 0,07190405 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,01518174 0,07176279 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01518174 0,07162208 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,01518174 0,07148192 ! striatum development GO:0021756 9 5 0,000 0,01518174 0,0713423 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,01518174 0,07120324 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,01518174 0,07106471 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,01518174 0,07092672 ! glial cell migration GO:0008347 11 5 0,000 0,01518174 0,07078926 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,01518174 0,07065234 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,01518174 0,07051595 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,01518174 0,07038008 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,01518174 0,07024473 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,01518174 0,0701099 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,01518174 0,06997559 ! neuroprotection GO:0043526 6 5 0,000 0,01518174 0,0698418 ! neural plate development GO:0001840 8 5 0,000 0,01518174 0,06970851 ! regulation of sensory perception GO:0051931 7 5 0,000 0,01518174 0,06957573 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,01518174 0,06944346 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,01518174 0,06931169 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,01518174 0,06918042 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,01518174 0,06904964 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,01518174 0,06891936 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,01518174 0,06878957 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,01518174 0,06866026 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,01518174 0,06853144 ! spindle assembly GO:0051225 6 5 0,000 0,01518174 0,06840311 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,01518174 0,06827525 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,01518174 0,06814787 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,01518174 0,06802097 ! drug metabolic process GO:0017144 6 5 0,000 0,01518174 0,06789453 ! stem cell division GO:0017145 11 5 0,000 0,01518174 0,06776857 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,01518174 0,06764307 ! organ regeneration GO:0031100 7 5 0,000 0,01518174 0,06751804 ! carnitine metabolic process GO:0009437 7 5 0,000 0,01518174 0,06739347 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,01518174 0,06726935 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,01518174 0,0671457 ! viral reproductive process GO:0022415 126 62 1,000 0,01549859 0,0684213 ! regulation of homeostatic process GO:0032844 134 62 1,000 0,01549859 0,06829598 ! developmental maturation GO:0021700 116 66 1,000 0,01744264 0,07672209 ! negative regulation of cell growth GO:0030308 132 67 1,000 0,01794404 0,07878349 ! activation of MAPK activity GO:0000187 115 67 1,000 0,01794404 0,07863998 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 1,000 0,01794404 0,078497 ! adaptive immune response GO:0002250 119 67 1,000 0,01794404 0,07835454 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,01819061 0,07928735 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,01819061 0,07914397 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,01819061 0,07900111 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,01819061 0,07885877 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,01819061 0,07871693 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,01819061 0,07857561 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,01819061 0,0784348 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,01819061 0,07829448 ! sleep GO:0030431 13 6 0,000 0,01819061 0,07815467 ! response to oxygen radical GO:0000305 11 6 0,000 0,01819061 0,07801536 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,01819061 0,07787654 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,01819061 0,07773822 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,01819061 0,07760038 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,01819061 0,07746304 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,01819061 0,07732618 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,01819061 0,0771898 ! forebrain regionalization GO:0021871 8 6 0,000 0,01819061 0,0770539 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,01819061 0,07691848 ! male meiosis GO:0007140 7 6 0,000 0,01819061 0,07678354 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,01819061 0,07664906 ! response to zinc ion GO:0010043 9 6 0,000 0,01819061 0,07651506 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,01819061 0,07638153 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,01819061 0,07624846 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,01819061 0,07611585 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,01819061 0,07598371 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,01819061 0,07585202 ! malate metabolic process GO:0006108 11 6 0,000 0,01819061 0,07572079 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,01819061 0,07559001 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,01819061 0,07545968 ! protein refolding GO:0042026 15 6 0,000 0,01819061 0,0753298 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,01819061 0,07520037 ! opsonization GO:0008228 8 6 0,000 0,01819061 0,07507138 ! mating behavior GO:0007617 7 6 0,000 0,01819061 0,07494284 ! neuron remodeling GO:0016322 15 6 0,000 0,01819061 0,07481473 ! erythrocyte maturation GO:0043249 7 6 0,000 0,01819061 0,07468706 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,01819061 0,07455982 ! equilibrioception GO:0050957 14 6 0,000 0,01819061 0,07443302 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,01819061 0,07430665 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,01819061 0,0741807 ! photoreceptor cell development GO:0042461 10 6 0,000 0,01819061 0,07405519 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,01819061 0,07393009 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,01819061 0,07380542 ! response to interferon-gamma GO:0034341 15 6 0,000 0,01819061 0,07368117 ! toxin metabolic process GO:0009404 11 6 0,000 0,01819061 0,07355734 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,01819061 0,07343392 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,01819061 0,07331091 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,01819061 0,07318832 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,01819061 0,07306614 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,01819061 0,07294436 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,01819061 0,07282299 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,01819061 0,07270202 ! thymic T cell selection GO:0045061 12 6 0,000 0,01819061 0,07258145 ! protein lipoylation GO:0009249 10 6 0,000 0,01819061 0,07246128 ! cysteine metabolic process GO:0006534 10 6 0,000 0,01819061 0,07234151 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,01819061 0,07222214 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,01819061 0,07210316 ! glutamate catabolic process GO:0006538 10 6 0,000 0,01819061 0,07198457 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,01819061 0,07186636 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,01819061 0,07174855 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,01819061 0,07163112 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,01819061 0,07151408 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,01819061 0,07139742 ! hyperosmotic response GO:0006972 9 6 0,000 0,01819061 0,07128113 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,01819061 0,07116523 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,01819061 0,0710497 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,01819061 0,07093455 ! urea metabolic process GO:0019627 7 6 0,000 0,01819061 0,07081977 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,01819061 0,07070536 ! neutrophil activation GO:0042119 8 6 0,000 0,01819061 0,07059132 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,01819061 0,07047764 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,01819061 0,07036433 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,01819061 0,07025139 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,01819061 0,07013881 ! neuron apoptosis GO:0051402 9 6 0,000 0,01819061 0,07002659 ! nucleoside salvage GO:0043174 9 6 0,000 0,01819061 0,06991472 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,01819061 0,06980321 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,01819061 0,06969206 ! T cell mediated immunity GO:0002456 16 6 0,000 0,01819061 0,06958127 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,01819061 0,06947082 GO:0010543|regulation of platelet activation, ! carnitine transport GO:0015879 10 6 0,000 0,01819061 0,06936072 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,01819061 0,06925097 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01819061 0,06914157 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,01819061 0,06903252 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,01819061 0,0689238 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,01819061 0,06881543 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,01819061 0,0687074 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,01819061 0,06859971 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,01819061 0,06849236 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,01819061 0,06838534 ! establishment of spindle localization GO:0051293 12 6 0,000 0,01819061 0,06827865 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,01819061 0,0681723 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,01819061 0,06806628 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,01819061 0,06796058 ! neural nucleus development GO:0048857 14 6 0,000 0,01819061 0,06785522 ! response to UV-C GO:0010225 11 6 0,000 0,01819061 0,06775018 ! astrocyte development GO:0014002 15 6 0,000 0,01819061 0,06764546 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,01819061 0,06754107 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,01819061 0,067437 ! interaction with symbiont GO:0051702 13 6 0,000 0,01819061 0,06733325 ! regulation of dendrite development GO:0050773 16 6 0,000 0,01819061 0,06722982 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,01819061 0,06712671 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,01819061 0,06702391 ! response to copper ion GO:0046688 10 6 0,000 0,01819061 0,06692143 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,01819061 0,06681926 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,01819061 0,0667174 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01819061 0,06661585 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,01819061 0,06651461 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,01819061 0,06641368 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,01819061 0,06631305 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,01819061 0,06621273 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,01819061 0,06611271 ! Schwann cell development GO:0014044 15 6 0,000 0,01819061 0,066013 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,01819061 0,06591358 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,01819061 0,06581446 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,01819061 0,06571564 ! subpallium development GO:0021544 10 6 0,000 0,01819061 0,06561712 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,01819061 0,06551889 ! histone ubiquitination GO:0016574 8 6 0,000 0,01819061 0,06542095 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,01819061 0,06532331 ! maintenance of organ identity GO:0048496 9 6 0,000 0,01819061 0,06522595 ! G2 phase GO:0051319 16 6 0,000 0,01819061 0,06512889 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,01819061 0,06503212 ! establishment of planar polarity GO:0001736 7 6 0,000 0,01819061 0,06493563 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,01819061 0,06483943 ! membrane to membrane docking GO:0022614 14 6 0,000 0,01819061 0,06474351 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,01819061 0,06464788 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,01819061 0,06455253 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,01819061 0,06445746 ! receptor internalization GO:0031623 10 6 0,000 0,01819061 0,06436267 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,01819061 0,06426816 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,01819061 0,06417392 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01819061 0,06407996 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,01819061 0,06398628 ! protein deubiquitination GO:0016579 14 6 0,000 0,01819061 0,06389287 ! protein destabilization GO:0031648 9 6 0,000 0,01819061 0,06379973 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,01819061 0,06370686 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,01819061 0,06361427 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,01819061 0,06352194 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,01819061 0,06342988 ! progesterone metabolic process GO:0042448 10 6 0,000 0,01819061 0,06333808 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,01819061 0,06324655 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,01819061 0,06315529 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,01819061 0,06306429 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,01819061 0,06297355 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,01819061 0,06288307 ! determination of adult lifespan GO:0008340 15 6 0,000 0,01819061 0,06279285 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,01819061 0,06270289 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,01819061 0,06261318 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,01819061 0,06252374 ! catecholamine transport GO:0051937 9 6 0,000 0,01819061 0,06243454 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,01819061 0,06234561 ! sensory cilium assembly GO:0035058 10 6 0,000 0,01819061 0,06225692 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,01819061 0,06216849 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,01819061 0,06208031 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,01819061 0,06199237 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,01819061 0,06190469 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,01819061 0,06181725 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,01819061 0,06173006 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,01819061 0,06164312 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,01819061 0,06155642 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,01819061 0,06146997 ! viral reproduction GO:0016032 134 68 1,000 0,01845151 0,06226413 ! regulation of lipase activity GO:0060191 130 68 1,000 0,01845151 0,06217693 ! cell cycle checkpoint GO:0000075 137 69 1,000 0,01896501 0,06381793 ! negative regulation of cell size GO:0045792 134 69 1,000 0,01896501 0,06372879 ! B cell activation GO:0042113 160 71 1,000 0,02000995 0,06714636 ! carbohydrate transport GO:0008643 110 72 1,000 0,0205413 0,0688334 ! axon guidance GO:0007411 139 73 1,000 0,02107853 0,07053538 ! tRNA transcription GO:0009304 14 7 0,000 0,0211904 0,07081124 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,0211904 0,07071303 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,0211904 0,07061509 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,0211904 0,07051742 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,0211904 0,07042002 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,0211904 0,07032289 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,0211904 0,07022602 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,0211904 0,07012943 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,0211904 0,0700331 ! prostate gland development GO:0030850 13 7 0,000 0,0211904 0,06993703 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,0211904 0,06984122 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,0211904 0,06974568 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,0211904 0,0696504 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,0211904 0,06955538 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,0211904 0,06946062 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,0211904 0,06936611 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,0211904 0,06927187 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 0,0211904 0,06917787 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,0211904 0,06908414 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,0211904 0,06899065 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,0211904 0,06889742 ! glycolipid transport GO:0046836 10 7 0,000 0,0211904 0,06880444 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,0211904 0,06871172 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,0211904 0,06861924 ! neuron adhesion GO:0007158 12 7 0,000 0,0211904 0,06852701 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,0211904 0,06843502 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,0211904 0,06834329 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,0211904 0,0682518 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,0211904 0,06816055 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,0211904 0,06806955 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,0211904 0,06797879 ! pericardium development GO:0060039 14 7 0,000 0,0211904 0,06788827 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,0211904 0,067798 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,0211904 0,06770796 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,0211904 0,06761816 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,0211904 0,0675286 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,0211904 0,06743928 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,0211904 0,06735019 ! lipoprotein transport GO:0042953 14 7 0,000 0,0211904 0,06726134 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,0211904 0,06717272 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,0211904 0,06708433 ! rhythmic behavior GO:0007622 15 7 0,000 0,0211904 0,06699618 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,0211904 0,06690826 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,0211904 0,06682057 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,0211904 0,06673311 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,0211904 0,06664587 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,0211904 0,06655887 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,0211904 0,06647209 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,0211904 0,06638554 ! mechanosensory behavior GO:0007638 14 7 0,000 0,0211904 0,06629921 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,0211904 0,06621311 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,0211904 0,06612723 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,0211904 0,06604157 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,0211904 0,06595614 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,0211904 0,06587092 ! spinal cord patterning GO:0021511 13 7 0,000 0,0211904 0,06578593 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,0211904 0,06570115 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,0211904 0,06561659 ! adrenal gland development GO:0030325 17 7 0,000 0,0211904 0,06553225 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,0211904 0,06544813 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,0211904 0,06536422 ! ovulation GO:0030728 9 7 0,000 0,0211904 0,06528053 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,0211904 0,06519705 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,0211904 0,06511378 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,0211904 0,06503073 ! microtubule nucleation GO:0007020 20 7 0,000 0,0211904 0,06494789 ! proline biosynthetic process GO:0006561 10 7 0,000 0,0211904 0,06486526 ! thyroid hormone generation GO:0006590 13 7 0,000 0,0211904 0,06478284 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,0211904 0,06470063 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,0211904 0,06461862 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,0211904 0,06453683 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,0211904 0,06445524 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,0211904 0,06437386 ! galactose metabolic process GO:0006012 13 7 0,000 0,0211904 0,06429268 ! vesicle fusion GO:0006906 17 7 0,000 0,0211904 0,0642117 ! response to dietary excess GO:0002021 8 7 0,000 0,0211904 0,06413094 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,0211904 0,06405037 ! intracellular pH reduction GO:0051452 11 7 0,000 0,0211904 0,06397 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,0211904 0,06388984 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,0211904 0,06380988 ! organ growth GO:0035265 15 7 0,000 0,0211904 0,06373012 ! purine salvage GO:0043101 10 7 0,000 0,0211904 0,06365055 ! nucleoside transport GO:0015858 8 7 0,000 0,0211904 0,06357119 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,0211904 0,06349202 ! parturition GO:0007567 14 7 0,000 0,0211904 0,06341305 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,0211904 0,06333428 ! rRNA modification GO:0000154 14 7 0,000 0,0211904 0,0632557 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,0211904 0,06317732 ! spindle checkpoint GO:0031577 15 7 0,000 0,0211904 0,06309913 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,0211904 0,06302113 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,0211904 0,06294333 ! macrophage differentiation GO:0030225 11 7 0,000 0,0211904 0,06286571 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,0211904 0,06278829 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,0211904 0,06271106 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,0211904 0,06263402 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,0211904 0,06255717 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,0211904 0,06248051 ! fibrinolysis GO:0042730 10 7 0,000 0,0211904 0,06240403 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,0211904 0,06232774 ! eating behavior GO:0042755 7 7 0,000 0,0211904 0,06225164 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,0211904 0,06217572 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,0211904 0,06209999 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,0211904 0,06202444 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,0211904 0,06194908 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,0211904 0,0618739 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,0211904 0,0617989 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,0211904 0,06172408 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,0211904 0,06164945 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,0211904 0,06157499 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,0211904 0,06150072 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,0211904 0,06142662 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,0211904 0,0613527 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,0211904 0,06127896 ! regulation of meiosis GO:0040020 12 7 0,000 0,0211904 0,06120539 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,0211904 0,06113201 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,0211904 0,06105879 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,0211904 0,06098576 ! oxygen homeostasis GO:0032364 12 7 0,000 0,0211904 0,0609129 ! transcription termination GO:0006353 13 7 0,000 0,0211904 0,06084021 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,0211904 0,06076769 ! anaphase GO:0051322 17 7 0,000 0,0211904 0,06069535 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,0211904 0,06062318 ! axonal fasciculation GO:0007413 18 7 0,000 0,0211904 0,06055118 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,0211904 0,06047935 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,0211904 0,06040769 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,0211904 0,06033621 ! diuresis GO:0030146 12 7 0,000 0,0211904 0,06026489 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,0211904 0,06019373 ! thiamin metabolic process GO:0006772 7 7 0,000 0,0211904 0,06012275 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,0211904 0,06005194 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,0211904 0,05998129 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,0211904 0,0599108 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,0211904 0,05984049 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,0211904 0,05977033 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,0211904 0,05970034 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,0211904 0,05963052 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,0211904 0,05956086 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,0211904 0,05949136 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,0211904 0,05942202 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,0211904 0,05935284 ! lymph node development GO:0048535 10 7 0,000 0,0211904 0,05928383 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,0211904 0,05921497 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,0211904 0,05914628 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,0211904 0,05907774 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,0211904 0,05900937 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,0211904 0,05894115 ! adult feeding behavior GO:0008343 9 7 0,000 0,0211904 0,05887309 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,0211904 0,05880518 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,0211904 0,05873743 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,0211904 0,05866984 ! muscle adaptation GO:0043500 14 7 0,000 0,0211904 0,05860241 ! embryonic heart tube development GO:0035050 10 7 0,000 0,0211904 0,05853512 ! retina homeostasis GO:0001895 12 7 0,000 0,0211904 0,058468 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,0211904 0,05840102 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,0211904 0,0583342 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,0211904 0,05826754 ! protein prenylation GO:0018342 18 7 0,000 0,0211904 0,05820102 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,0211904 0,05813466 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,0211904 0,05806844 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,0211904 0,05800238 ! regulation of transcription factor activity GO:0051090 126 74 1,000 0,02162158 0,05911537 GO:0090046|regulation of transcription regulator activity, ! phosphoinositide-mediated signaling GO:0048015 131 75 1,000 0,02217043 0,06054716 ! lymphocyte differentiation GO:0030098 167 75 1,000 0,02217043 0,06047851 ! regulation of catabolic process GO:0009894 161 76 1,000 0,02272502 0,06192118 ! negative regulation of organelle organization GO:0010639 161 78 1,000 0,0238513 0,06491656 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,02418111 0,06573984 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,02418111 0,06566564 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,02418111 0,06559161 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,02418111 0,06551775 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,02418111 0,06544405 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,02418111 0,06537051 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,02418111 0,06529715 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,02418111 0,06522394 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,02418111 0,0651509 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,02418111 0,06507803 ! meiotic prophase I GO:0007128 13 8 0,000 0,02418111 0,06500532 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,02418111 0,06493277 ! oligopeptide transport GO:0006857 15 8 0,000 0,02418111 0,06486038 ! UTP metabolic process GO:0046051 8 8 0,000 0,02418111 0,06478815 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,02418111 0,06471608 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,02418111 0,06464418 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,02418111 0,06457243 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,02418111 0,06450084 ! succinate metabolic process GO:0006105 14 8 0,000 0,02418111 0,06442941 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,02418111 0,06435814 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,02418111 0,06428703 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,02418111 0,06421607 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,02418111 0,06414527 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,02418111 0,06407462 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,02418111 0,06400413 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,02418111 0,0639338 ! reflex GO:0060004 16 8 0,000 0,02418111 0,06386362 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,02418111 0,06379359 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,02418111 0,06372372 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,02418111 0,063654 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,02418111 0,06358444 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,02418111 0,06351502 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,02418111 0,06344576 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,02418111 0,06337664 ! pigment granule organization GO:0048753 16 8 0,000 0,02418111 0,06330768 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,02418111 0,06323887 ! astrocyte differentiation GO:0048708 18 8 0,000 0,02418111 0,0631702 ! histidine metabolic process GO:0006547 16 8 0,000 0,02418111 0,06310169 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,02418111 0,06303332 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,02418111 0,06296511 ! glycine catabolic process GO:0006546 13 8 0,000 0,02418111 0,06289704 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,02418111 0,06282911 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,02418111 0,06276134 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,02418111 0,0626937 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,02418111 0,06262622 ! melanin metabolic process GO:0006582 15 8 0,000 0,02418111 0,06255888 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,02418111 0,06249168 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,02418111 0,06242463 ! macrophage activation GO:0042116 12 8 0,000 0,02418111 0,06235773 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,02418111 0,06229096 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,02418111 0,06222434 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,02418111 0,06215786 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,02418111 0,06209152 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,02418111 0,06202533 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,02418111 0,06195927 ! osteoblast development GO:0002076 16 8 0,000 0,02418111 0,06189336 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,02418111 0,06182759 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,02418111 0,06176195 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,02418111 0,06169646 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,02418111 0,0616311 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,02418111 0,06156588 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,02418111 0,0615008 ! response to UV-B GO:0010224 16 8 0,000 0,02418111 0,06143586 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,02418111 0,06137105 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,02418111 0,06130638 ! intermediate filament organization GO:0045109 12 8 0,000 0,02418111 0,06124185 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,02418111 0,06117745 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,02418111 0,06111319 ! cellular extravasation GO:0045123 12 8 0,000 0,02418111 0,06104906 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,02418111 0,06098507 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,02418111 0,06092121 ! response to antibiotic GO:0046677 11 8 0,000 0,02418111 0,06085749 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,02418111 0,0607939 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,02418111 0,06073044 ! DNA topological change GO:0006265 12 8 0,000 0,02418111 0,06066711 ! response to tropane GO:0014073 15 8 0,000 0,02418111 0,06060391 GO:0042220|response to cocaine, ! melanosome transport GO:0032402 13 8 0,000 0,02418111 0,06054085 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,02418111 0,06047792 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,02418111 0,06041512 ! mast cell activation GO:0045576 14 8 0,000 0,02418111 0,06035245 ! multicellular organismal aging GO:0010259 18 8 0,000 0,02418111 0,0602899 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,02418111 0,06022749 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,02418111 0,06016521 ! nucleosome disassembly GO:0006337 14 8 0,000 0,02418111 0,06010306 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,02418111 0,06004103 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,02418111 0,05997913 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,02418111 0,05991736 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,02418111 0,05985572 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,02418111 0,0597942 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,02418111 0,05973281 ! intracellular lipid transport GO:0032365 13 8 0,000 0,02418111 0,05967155 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,02418111 0,05961041 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,02418111 0,05954939 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,02418111 0,05948851 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,02418111 0,05942774 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,02418111 0,0593671 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,02418111 0,05930658 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,02418111 0,05924619 ! hormone catabolic process GO:0042447 17 8 0,000 0,02418111 0,05918592 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,02418111 0,05912577 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,02418111 0,05906574 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,02418111 0,05900584 ! ATP catabolic process GO:0006200 11 8 0,000 0,02418111 0,05894606 ! blastocyst growth GO:0001832 19 8 0,000 0,02418111 0,05888639 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,02418111 0,05882685 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,02418111 0,05876743 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,02418111 0,05870813 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,02418111 0,05864895 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,02418111 0,05858989 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,02418111 0,05853094 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,02418111 0,05847212 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,02418111 0,05841341 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,02418111 0,05835482 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,02418111 0,05829635 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,02418111 0,058238 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,02418111 0,05817976 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,02418111 0,05812164 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,02418111 0,05806363 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,02418111 0,05800574 GO:0000076|DNA replication checkpoint, ! NAD biosynthetic process GO:0009435 13 8 0,000 0,02418111 0,05794797 ! activation of protein kinase activity GO:0032147 147 79 1,000 0,02442291 0,05846918 ! positive regulation of phosphorylation GO:0042327 129 79 1,000 0,02442291 0,05841106 ! cellular lipid catabolic process GO:0044242 134 80 1,000 0,02500012 0,05973216 ! protein import into nucleus GO:0006606 158 80 1,000 0,02500012 0,0596729 ! T cell activation GO:0042110 168 81 1,000 0,02558288 0,06100337 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 1,000 0,02558288 0,06094297 GO:0045937|positive regulation of phosphate metabolic process, ! cell-substrate adhesion GO:0031589 171 81 1,000 0,02558288 0,06088269 ! nuclear import GO:0051170 161 81 1,000 0,02558288 0,06082253 ! cholesterol metabolic process GO:0008203 136 82 1,000 0,02617115 0,06215971 ! response to drug GO:0042493 143 82 1,000 0,02617115 0,06209841 ! axon extension GO:0048675 15 9 0,000 0,02716279 0,06438786 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,02716279 0,06432448 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,02716279 0,06426123 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,02716279 0,06419811 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,02716279 0,06413511 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,02716279 0,06407223 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,02716279 0,06400948 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,02716279 0,06394684 ! phosphate transport GO:0006817 19 9 0,000 0,02716279 0,06388434 ! reproductive behavior GO:0019098 19 9 0,000 0,02716279 0,06382195 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,02716279 0,06375968 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,02716279 0,06369754 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,02716279 0,06363552 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,02716279 0,06357361 ! GTP metabolic process GO:0046039 9 9 0,000 0,02716279 0,06351183 ! RNA methylation GO:0001510 15 9 0,000 0,02716279 0,06345017 ! elastic fiber assembly GO:0048251 15 9 0,000 0,02716279 0,06338863 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,02716279 0,0633272 ! artery development GO:0060840 24 9 0,000 0,02716279 0,0632659 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,02716279 0,06320471 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,02716279 0,06314365 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,02716279 0,0630827 ! chemosensory behavior GO:0007635 20 9 0,000 0,02716279 0,06302187 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,02716279 0,06296115 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,02716279 0,06290055 ! leukocyte degranulation GO:0043299 16 9 0,000 0,02716279 0,06284007 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,02716279 0,06277971 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,02716279 0,06271946 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,02716279 0,06265932 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,02716279 0,06259931 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,02716279 0,0625394 ! protein targeting to ER GO:0045047 22 9 0,000 0,02716279 0,06247961 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,02716279 0,06241994 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,02716279 0,06236038 ! T cell selection GO:0045058 23 9 0,000 0,02716279 0,06230093 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,02716279 0,0622416 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,02716279 0,06218237 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,02716279 0,06212327 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,02716279 0,06206427 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,02716279 0,06200538 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,02716279 0,06194661 ! mannose metabolic process GO:0006013 13 9 0,000 0,02716279 0,06188795 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,02716279 0,0618294 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,02716279 0,06177096 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,02716279 0,06171263 ! receptor clustering GO:0043113 18 9 0,000 0,02716279 0,06165441 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,02716279 0,0615963 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,02716279 0,0615383 ! ruffle organization GO:0031529 15 9 0,000 0,02716279 0,06148041 ! retinol metabolic process GO:0042572 18 9 0,000 0,02716279 0,06142263 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,02716279 0,06136495 ! behavioral fear response GO:0001662 22 9 0,000 0,02716279 0,06130739 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,02716279 0,06124993 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,02716279 0,06119258 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,02716279 0,06113534 GO:0030204|chondroitin sulfate metabolic process, ! oligodendrocyte development GO:0014003 10 9 0,000 0,02716279 0,0610782 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,02716279 0,06102117 ! segment specification GO:0007379 13 9 0,000 0,02716279 0,06096425 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,02716279 0,06090743 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,02716279 0,06085072 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,02716279 0,06079412 ! response to amine stimulus GO:0014075 13 9 0,000 0,02716279 0,06073762 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,02716279 0,06068122 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,02716279 0,06062493 ! erythrocyte development GO:0048821 15 9 0,000 0,02716279 0,06056874 ! gas homeostasis GO:0033483 16 9 0,000 0,02716279 0,06051266 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,02716279 0,06045668 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,02716279 0,06040081 ! renal water homeostasis GO:0003091 14 9 0,000 0,02716279 0,06034504 ! postreplication repair GO:0006301 22 9 0,000 0,02716279 0,06028937 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,02716279 0,0602338 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,02716279 0,06017834 ! icosanoid secretion GO:0032309 15 9 0,000 0,02716279 0,06012298 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,02716279 0,06006772 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,02716279 0,06001256 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,02716279 0,0599575 ! regulation of cell division GO:0051302 15 9 0,000 0,02716279 0,05990254 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,02716279 0,05984769 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,02716279 0,05979293 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,02716279 0,05973828 ! sterol catabolic process GO:0016127 11 9 0,000 0,02716279 0,05968372 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,02716279 0,05962927 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,02716279 0,05957491 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,02716279 0,05952065 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,02716279 0,05946649 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,02716279 0,05941243 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,02716279 0,05935847 ! musculoskeletal movement GO:0050881 14 9 0,000 0,02716279 0,05930461 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,02716279 0,05925084 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,02716279 0,05919717 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,02716279 0,0591436 ! purine base metabolic process GO:0006144 21 9 0,000 0,02716279 0,05909012 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,02716279 0,05903674 ! pigment granule transport GO:0051904 17 9 0,000 0,02716279 0,05898346 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,02716279 0,05893027 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,02716279 0,05887718 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,02716279 0,05882419 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,02716279 0,05877129 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,02716279 0,05871849 ! mitochondrion localization GO:0051646 15 9 0,000 0,02716279 0,05866578 ! negative regulation of growth GO:0045926 155 84 1,000 0,0273641 0,05904755 ! mitochondrion organization GO:0007005 148 86 1,000 0,02857865 0,06161311 ! protein localization in nucleus GO:0034504 176 87 1,000 0,02919394 0,06288327 ! regulation of protein transport GO:0051223 154 87 1,000 0,02919394 0,06282702 GO:0070201|regulation of establishment of protein localization, ! regulation of DNA binding GO:0051101 155 88 1,000 0,02981451 0,06410519 ! gland development GO:0048732 206 88 1,000 0,02981451 0,06404796 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,03013546 0,06467967 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 0,000 0,03013546 0,06462202 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,03013546 0,06456448 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,03013546 0,06450704 ! positive regulation of B cell proliferation GO:0030890 16 10 0,000 0,03013546 0,0644497 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,03013546 0,06439246 ! synapsis GO:0007129 13 10 0,000 0,03013546 0,06433532 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,03013546 0,06427829 ! N-glycan processing GO:0006491 20 10 0,000 0,03013546 0,06422135 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,03013546 0,06416452 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,03013546 0,06410779 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,03013546 0,06405116 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,03013546 0,06399462 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,03013546 0,06393819 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,03013546 0,06388186 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,03013546 0,06382562 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,03013546 0,06376949 ! androgen metabolic process GO:0008209 17 10 0,000 0,03013546 0,06371345 ! phospholipid efflux GO:0033700 16 10 0,000 0,03013546 0,06365751 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,03013546 0,06360167 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,03013546 0,06354593 ! pathogenesis GO:0009405 13 10 0,000 0,03013546 0,06349029 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,03013546 0,06343474 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,03013546 0,06337929 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,03013546 0,06332394 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,03013546 0,06326868 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,03013546 0,06321352 ! endoderm development GO:0007492 16 10 0,000 0,03013546 0,06315846 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,03013546 0,06310349 ! arginine catabolic process GO:0006527 13 10 0,000 0,03013546 0,06304862 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,03013546 0,06299384 ! proline metabolic process GO:0006560 13 10 0,000 0,03013546 0,06293916 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,03013546 0,06288457 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,03013546 0,06283008 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,03013546 0,06277568 ! V(D)J recombination GO:0033151 28 10 0,000 0,03013546 0,06272137 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,03013546 0,06266716 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,03013546 0,06261305 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,03013546 0,06255902 ! B cell proliferation GO:0042100 18 10 0,000 0,03013546 0,06250509 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,03013546 0,06245126 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,03013546 0,06239751 ! multicellular organism growth GO:0035264 18 10 0,000 0,03013546 0,06234386 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,03013546 0,0622903 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,03013546 0,06223683 ! epithelial cell development GO:0002064 20 10 0,000 0,03013546 0,06218346 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,03013546 0,06213017 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,03013546 0,06207698 ! macroautophagy GO:0016236 17 10 0,000 0,03013546 0,06202387 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,03013546 0,06197086 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,03013546 0,06191794 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,03013546 0,06186511 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,03013546 0,06181237 ! copper ion homeostasis GO:0055070 13 10 0,000 0,03013546 0,06175972 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,03013546 0,06170716 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,03013546 0,06165468 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,03013546 0,0616023 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,03013546 0,06155001 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,03013546 0,0614978 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,03013546 0,06144569 ! blastoderm segmentation GO:0007350 18 10 0,000 0,03013546 0,06139366 ! response to dsRNA GO:0043331 20 10 0,000 0,03013546 0,06134172 ! DNA ligation GO:0006266 19 10 0,000 0,03013546 0,06128986 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,03013546 0,0612381 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,03013546 0,06118642 ! melanosome localization GO:0032400 16 10 0,000 0,03013546 0,06113483 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,03013546 0,06108333 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,03013546 0,06103191 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,03013546 0,06098058 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,03013546 0,06092934 ! mRNA cleavage GO:0006379 17 10 0,000 0,03013546 0,06087818 ! protein sumoylation GO:0016925 15 10 0,000 0,03013546 0,0608271 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,03013546 0,06077612 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,03013546 0,06072522 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,03013546 0,0606744 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,03013546 0,06062367 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,03013546 0,06057302 ! salivary gland development GO:0007431 27 10 0,000 0,03013546 0,06052246 ! prophase GO:0051324 15 10 0,000 0,03013546 0,06047198 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,03013546 0,06042159 ! apical protein localization GO:0045176 15 10 0,000 0,03013546 0,06037128 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,03013546 0,06032106 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,03013546 0,06027091 ! midbrain development GO:0030901 13 10 0,000 0,03013546 0,06022085 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,03013546 0,06017088 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,03013546 0,06012099 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,03013546 0,06007118 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,03013546 0,06002145 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,03013546 0,0599718 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,03013546 0,05992224 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,03013546 0,05987276 ! detection of calcium ion GO:0005513 23 10 0,000 0,03013546 0,05982336 ! oocyte development GO:0048599 17 10 0,000 0,03013546 0,05977404 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,03013546 0,0597248 ! blastocyst formation GO:0001825 17 10 0,000 0,03013546 0,05967565 ! cerebellar cortex development GO:0021695 15 10 0,000 0,03013546 0,05962657 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,03013546 0,05957758 ! activation of innate immune response GO:0002218 12 10 0,000 0,03013546 0,05952866 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,03013546 0,05947983 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,03013546 0,05943107 ! response to nicotine GO:0035094 20 10 0,000 0,03013546 0,0593824 ! establishment of cell polarity GO:0030010 16 10 0,000 0,03013546 0,0593338 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,03013546 0,05928529 ! regulation of cell morphogenesis GO:0022604 215 89 1,000 0,03044034 0,05983615 ! ossification GO:0001503 188 90 1,000 0,03107138 0,06102672 ! bone development GO:0060348 189 91 1,000 0,0317076 0,06222551 ! sterol metabolic process GO:0016125 152 91 1,000 0,0317076 0,0621748 ! vitamin metabolic process GO:0006766 139 92 1,000 0,03234896 0,06338077 ! negative regulation of multicellular organismal process GO:0051241 166 93 1,000 0,03299542 0,06459478 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,03309914 0,06474514 ! respiratory burst GO:0045730 17 11 0,000 0,03309914 0,06469255 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,03309914 0,06464004 ! neuron fate specification GO:0048665 17 11 0,000 0,03309914 0,06458761 ! telencephalon cell migration GO:0022029 20 11 0,000 0,03309914 0,06453527 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,03309914 0,06448302 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,03309914 0,06443085 ! thyroid gland development GO:0030878 26 11 0,000 0,03309914 0,06437876 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,03309914 0,06432676 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,03309914 0,06427484 ! response to pain GO:0048265 24 11 0,000 0,03309914 0,064223 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,03309914 0,06417125 ! T cell proliferation GO:0042098 26 11 0,000 0,03309914 0,06411959 ! bone resorption GO:0045453 16 11 0,000 0,03309914 0,064068 ! ventral spinal cord development GO:0021517 21 11 0,000 0,03309914 0,0640165 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,03309914 0,06396508 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,03309914 0,06391374 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,03309914 0,06386249 ! melanocyte differentiation GO:0030318 21 11 0,000 0,03309914 0,06381132 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,03309914 0,06376023 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,03309914 0,06370922 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,03309914 0,06365829 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,03309914 0,06360745 GO:0043088|regulation of Cdc42 GTPase activity, ! lipid digestion GO:0044241 18 11 0,000 0,03309914 0,06355668 ! UV protection GO:0009650 19 11 0,000 0,03309914 0,063506 ! adult heart development GO:0007512 14 11 0,000 0,03309914 0,0634554 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,03309914 0,06340488 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,03309914 0,06335444 ! temperature homeostasis GO:0001659 17 11 0,000 0,03309914 0,06330407 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,03309914 0,06325379 ! negative regulation of ossification GO:0030279 26 11 0,000 0,03309914 0,06320359 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,03309914 0,06315347 ! regulation of organ growth GO:0046620 13 11 0,000 0,03309914 0,06310343 ! pigment granule localization GO:0051875 20 11 0,000 0,03309914 0,06305346 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,03309914 0,06300358 ! vasoconstriction GO:0042310 18 11 0,000 0,03309914 0,06295377 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,03309914 0,06290405 ! embryonic axis specification GO:0000578 18 11 0,000 0,03309914 0,0628544 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,03309914 0,06280483 ! snRNA metabolic process GO:0016073 24 11 0,000 0,03309914 0,06275534 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,03309914 0,06270593 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,03309914 0,06265659 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,03309914 0,06260733 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,03309914 0,06255815 ! zymogen activation GO:0031638 15 11 0,000 0,03309914 0,06250905 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,03309914 0,06246002 ! neuroblast proliferation GO:0007405 24 11 0,000 0,03309914 0,06241107 ! nucleosome positioning GO:0016584 15 11 0,000 0,03309914 0,0623622 ! regulation of isotype switching GO:0045191 22 11 0,000 0,03309914 0,0623134 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,03309914 0,06226468 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,03309914 0,06221604 ! acid secretion GO:0046717 18 11 0,000 0,03309914 0,06216747 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,03309914 0,06211897 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,03309914 0,06207056 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,03309914 0,06202222 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,03309914 0,06197395 ! oocyte differentiation GO:0009994 18 11 0,000 0,03309914 0,06192576 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,03309914 0,06187764 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,03309914 0,0618296 ! cholesterol efflux GO:0033344 19 11 0,000 0,03309914 0,06178163 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,03309914 0,06173374 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,03309914 0,06168592 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,03309914 0,06163818 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,03309914 0,06159051 ! embryonic gut development GO:0048566 15 11 0,000 0,03309914 0,06154291 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,03309914 0,06149539 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,03309914 0,06144794 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,03309914 0,06140056 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,03309914 0,06135326 ! defense response to fungus GO:0050832 13 11 0,000 0,03309914 0,06130602 ! developmental induction GO:0031128 19 11 0,000 0,03309914 0,06125887 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,03309914 0,06121178 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,03309914 0,06116477 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,03309914 0,06111782 ! sequestering of metal ion GO:0051238 14 11 0,000 0,03309914 0,06107095 ! lamellipodium assembly GO:0030032 20 11 0,000 0,03309914 0,06102416 ! nucleus localization GO:0051647 19 11 0,000 0,03309914 0,06097743 ! regulation of synapse organization GO:0050807 17 11 0,000 0,03309914 0,06093078 ! female pregnancy GO:0007565 164 94 1,000 0,03364695 0,06189187 ! regulation of T cell activation GO:0050863 158 94 1,000 0,03364695 0,06184459 ! leukocyte differentiation GO:0002521 202 96 1,000 0,03496507 0,06421829 ! protein ubiquitination GO:0016567 217 97 1,000 0,03563159 0,06539253 ! regulation of protein localization GO:0032880 176 97 1,000 0,03563159 0,06534269 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,03605386 0,06606671 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,03605386 0,06601643 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,03605386 0,06596623 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,03605386 0,0659161 ! regulation of B cell proliferation GO:0030888 20 12 0,000 0,03605386 0,06586605 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,03605386 0,06581608 ! cartilage condensation GO:0001502 20 12 0,000 0,03605386 0,06576618 ! mating GO:0007618 17 12 0,000 0,03605386 0,06571635 ! protein complex disassembly GO:0043241 27 12 0,000 0,03605386 0,06566661 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,03605386 0,06561693 ! hippocampus development GO:0021766 26 12 0,000 0,03605386 0,06556734 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,03605386 0,06551782 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,03605386 0,06546837 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,03605386 0,065419 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,03605386 0,0653697 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,03605386 0,06532047 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,03605386 0,06527132 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,03605386 0,06522225 ! drug transport GO:0015893 16 12 0,000 0,03605386 0,06517324 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,03605386 0,06512432 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,03605386 0,06507546 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,03605386 0,06502668 ! polyamine metabolic process GO:0006595 17 12 0,000 0,03605386 0,06497797 ! focal adhesion formation GO:0048041 35 12 0,000 0,03605386 0,06492933 ! mitotic spindle organization GO:0007052 21 12 0,000 0,03605386 0,06488077 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,03605386 0,06483228 ! forebrain cell migration GO:0021885 21 12 0,000 0,03605386 0,06478386 ! asymmetric protein localization GO:0008105 20 12 0,000 0,03605386 0,06473551 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,03605386 0,06468724 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,03605386 0,06463904 ! entry into host cell GO:0030260 32 12 0,000 0,03605386 0,06459091 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,03605386 0,06454285 ! monoamine transport GO:0015844 18 12 0,000 0,03605386 0,06449486 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,03605386 0,06444694 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,03605386 0,0643991 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,03605386 0,06435133 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,03605386 0,06430362 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,03605386 0,06425599 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,03605386 0,06420843 ! protein homotetramerization GO:0051289 21 12 0,000 0,03605386 0,06416094 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,03605386 0,06411352 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,03605386 0,06406617 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,03605386 0,06401888 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,03605386 0,06397167 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,03605386 0,06392453 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,03605386 0,06387746 ! cranial nerve development GO:0021545 20 12 0,000 0,03605386 0,06383045 ! fucose catabolic process GO:0019317 22 12 0,000 0,03605386 0,06378352 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,03605386 0,06373666 ! histone methylation GO:0016571 26 12 0,000 0,03605386 0,06368986 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,03605386 0,06364313 ! autonomic nervous system development GO:0048483 24 12 0,000 0,03605386 0,06359647 ! gland morphogenesis GO:0022612 29 12 0,000 0,03605386 0,06354988 ! T cell homeostasis GO:0043029 25 12 0,000 0,03605386 0,06350336 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,03605386 0,0634569 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,03605386 0,06341052 ! spleen development GO:0048536 22 12 0,000 0,03605386 0,0633642 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,03605386 0,06331795 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,03605386 0,06327176 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,03605386 0,06322565 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,03605386 0,0631796 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,03605386 0,06313362 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,03605386 0,0630877 ! response to cold GO:0009409 17 12 0,000 0,03605386 0,06304185 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,03605386 0,06299607 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,03605386 0,06295035 ! carboxylic acid catabolic process GO:0046395 156 98 1,000 0,03630303 0,06333945 GO:0016054|organic acid catabolic process, ! cGMP metabolic process GO:0046068 18 13 0,000 0,03899965 0,06799504 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,03899965 0,06794581 ! regulation of chemokine production GO:0032642 18 13 0,000 0,03899965 0,06789664 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,03899965 0,06784755 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,03899965 0,06779853 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,03899965 0,06774957 ! lipid localization GO:0010876 28 13 0,000 0,03899965 0,06770069 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,03899965 0,06765188 ! organelle fusion GO:0048284 32 13 0,000 0,03899965 0,06760314 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,03899965 0,06755447 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,03899965 0,06750587 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,03899965 0,06745734 ! endocrine pancreas development GO:0031018 22 13 0,000 0,03899965 0,06740888 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,03899965 0,06736049 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,03899965 0,06731217 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,03899965 0,06726391 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,03899965 0,06721573 ! methionine metabolic process GO:0006555 27 13 0,000 0,03899965 0,06716762 ! plasma membrane organization GO:0007009 24 13 0,000 0,03899965 0,06711957 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,03899965 0,06707159 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,03899965 0,06702369 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,03899965 0,06697585 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,03899965 0,06692808 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,03899965 0,06688037 ! cytokine metabolic process GO:0042107 22 13 0,000 0,03899965 0,06683274 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,03899965 0,06678517 ! exocrine system development GO:0035272 32 13 0,000 0,03899965 0,06673767 ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,03899965 0,06669024 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,03899965 0,06664287 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,03899965 0,06659557 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,03899965 0,06654834 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,03899965 0,06650118 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,03899965 0,06645408 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,03899965 0,06640705 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,03899965 0,06636009 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,03899965 0,06631319 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,03899965 0,06626636 ! ribosome assembly GO:0042255 17 13 0,000 0,03899965 0,06621959 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,03899965 0,06617289 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,03899965 0,06612626 ! chromatin silencing GO:0006342 26 13 0,000 0,03899965 0,06607969 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,03899965 0,06603319 ! regulation of epidermis development GO:0045682 19 13 0,000 0,03899965 0,06598675 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,03899965 0,06594038 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,03899965 0,06589407 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,03899965 0,06584783 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,03899965 0,06580166 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,03899965 0,06575554 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,03899965 0,0657095 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,03899965 0,06566351 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,03899965 0,0656176 ! embryonic placenta development GO:0001892 23 13 0,000 0,03899965 0,06557174 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,03899965 0,06552595 ! insulin secretion GO:0030073 23 13 0,000 0,03899965 0,06548022 ! actin filament polymerization GO:0030041 24 13 0,000 0,03899965 0,06543456 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,03899965 0,06538896 ! acrosome reaction GO:0007340 18 13 0,000 0,03899965 0,06534343 ! rRNA transcription GO:0009303 25 14 0,000 0,04193654 0,07021525 ! lactation GO:0007595 26 14 0,000 0,04193654 0,07016642 ! reproductive cellular process GO:0048610 20 14 0,000 0,04193654 0,07011766 ! tRNA modification GO:0006400 20 14 0,000 0,04193654 0,07006897 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,04193654 0,07002034 ! regulation of S phase GO:0033261 23 14 0,000 0,04193654 0,06997178 ! water transport GO:0006833 21 14 0,000 0,04193654 0,06992329 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,04193654 0,06987487 ! non-recombinational repair GO:0000726 25 14 0,000 0,04193654 0,06982651 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,04193654 0,06977822 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,04193654 0,06973 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,04193654 0,06968184 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,04193654 0,06963375 ! RNA polyadenylation GO:0043631 30 14 0,000 0,04193654 0,06958573 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,04193654 0,06953777 ! palate development GO:0060021 31 14 0,000 0,04193654 0,06948988 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,04193654 0,06944206 ! regulated secretory pathway GO:0045055 23 14 0,000 0,04193654 0,0693943 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,04193654 0,06934661 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,04193654 0,06929898 ! arginine metabolic process GO:0006525 17 14 0,000 0,04193654 0,06925141 ! regulation of heart rate GO:0002027 24 14 0,000 0,04193654 0,06920392 ! organic alcohol transport GO:0015850 29 14 0,000 0,04193654 0,06915648 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,04193654 0,06910912 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,04193654 0,06906181 GO:0060675|ureteric bud morphogenesis, ! neutral amino acid transport GO:0015804 26 14 0,000 0,04193654 0,06901458 ! L-amino acid transport GO:0015807 30 14 0,000 0,04193654 0,0689674 ! bone mineralization GO:0030282 17 14 0,000 0,04193654 0,06892029 ! stem cell development GO:0048864 43 14 0,000 0,04193654 0,06887325 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,04193654 0,06882627 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,04193654 0,06877935 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,04193654 0,0687325 ! cerebellum development GO:0021549 21 14 0,000 0,04193654 0,06868571 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,04193654 0,06863899 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,04193654 0,06859233 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,04193654 0,06854573 ! cofactor transport GO:0051181 26 14 0,000 0,04193654 0,06849919 ! NADP metabolic process GO:0006739 24 14 0,000 0,04193654 0,06845272 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,04193654 0,06840631 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,04193654 0,06835997 ! intestinal absorption GO:0050892 25 14 0,000 0,04193654 0,06831368 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,04193654 0,06826746 ! oxygen transport GO:0015671 21 14 0,000 0,04193654 0,06822131 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,04193654 0,06817521 ! male genitalia development GO:0030539 24 14 0,000 0,04193654 0,06812918 ! regulation of axon extension GO:0030516 37 14 0,000 0,04193654 0,06808321 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,04193654 0,0680373 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,04486455 0,07273861 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,04486455 0,07268963 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,04486455 0,07264071 ! superoxide anion generation GO:0042554 20 15 0,000 0,04486455 0,07259186 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,04486455 0,07254308 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,04486455 0,07249436 ! copper ion transport GO:0006825 20 15 0,000 0,04486455 0,0724457 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,04486455 0,07239712 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,04486455 0,07234859 ! sulfate transport GO:0008272 23 15 0,000 0,04486455 0,07230013 ! response to cAMP GO:0051591 22 15 0,000 0,04486455 0,07225174 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,04486455 0,07220341 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,04486455 0,07215515 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,04486455 0,07210695 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,04486455 0,07205881 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,04486455 0,07201074 ! response to hexose stimulus GO:0009746 22 15 0,000 0,04486455 0,07196273 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,04486455 0,07191479 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,04486455 0,07186691 ! pituitary gland development GO:0021983 29 15 0,000 0,04486455 0,07181909 ! vesicle coating GO:0006901 33 15 0,000 0,04486455 0,07177134 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,04486455 0,07172365 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,04486455 0,07167603 ! regulation of exocytosis GO:0017157 22 15 0,000 0,04486455 0,07162847 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,04486455 0,07158097 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,04486455 0,07153353 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,04486455 0,07148616 ! regulation of vasodilation GO:0042312 26 15 0,000 0,04486455 0,07143885 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,04486455 0,0713916 ! histone deacetylation GO:0016575 20 15 0,000 0,04486455 0,07134441 ! mRNA splice site selection GO:0006376 38 15 0,000 0,04486455 0,07129729 ! tissue regeneration GO:0042246 26 15 0,000 0,04486455 0,07125023 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,04486455 0,07120323 ! water homeostasis GO:0030104 27 15 0,000 0,04486455 0,07115629 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,04486455 0,07110942 ! muscle maintenance GO:0046716 26 15 0,000 0,04486455 0,07106261 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,04486455 0,07101585 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,04486455 0,07096916 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,04486455 0,07092254 ! dopamine metabolic process GO:0042417 35 15 0,000 0,04486455 0,07087597 ! heme biosynthetic process GO:0006783 29 15 0,000 0,04486455 0,07082946 ! cell killing GO:0001906 29 15 0,000 0,04486455 0,07078302 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,04486455 0,07073663 ! detection of bacterium GO:0016045 18 15 0,000 0,04486455 0,07069031 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,04486455 0,07064404 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,04486455 0,07059784 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,04486455 0,0705517 ! peptide hormone processing GO:0016486 23 15 0,000 0,04486455 0,07050562 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,0477837 0,07504412 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,0477837 0,07499517 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,0477837 0,07494628 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,0477837 0,07489745 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,0477837 0,07484869 ! bone remodeling GO:0046849 27 16 0,000 0,0477837 0,07479999 ! filopodium assembly GO:0046847 32 16 0,000 0,0477837 0,07475136 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,0477837 0,07470279 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,0477837 0,07465428 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,0477837 0,07460583 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,0477837 0,07455745 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,0477837 0,07450913 ! startle response GO:0001964 28 16 0,000 0,0477837 0,07446087 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,0477837 0,07441268 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,0477837 0,07436455 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,0477837 0,07431648 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,0477837 0,07426847 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,0477837 0,07422052 ! protein polyubiquitination GO:0000209 34 16 0,000 0,0477837 0,07417264 ! glutamate metabolic process GO:0006536 22 16 0,000 0,0477837 0,07412482 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,0477837 0,07407706 ! response to osmotic stress GO:0006970 25 16 0,000 0,0477837 0,07402936 ! lysosomal transport GO:0007041 26 16 0,000 0,0477837 0,07398172 ! fructose metabolic process GO:0006000 25 16 0,000 0,0477837 0,07393414 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,0477837 0,07388663 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,0477837 0,07383917 ! intermediate filament-based process GO:0045103 32 16 0,000 0,0477837 0,07379178 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,0477837 0,07374445 ! negative regulation of immune response GO:0050777 35 16 0,000 0,0477837 0,07369717 ! axon cargo transport GO:0008088 43 16 0,000 0,0477837 0,07364996 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,0477837 0,07360281 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,0477837 0,07355572 ! DNA replication initiation GO:0006270 27 16 0,000 0,0477837 0,07350869 ! neuron recognition GO:0008038 35 16 0,000 0,0477837 0,07346172 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,0477837 0,07341481 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,0477837 0,07336796 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,0477837 0,07332117 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,0477837 0,07327444 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,0477837 0,07322776 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,0477837 0,07318115 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,0477837 0,0731346 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,0477837 0,07308811 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,0477837 0,07304167 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,0477837 0,0729953 ! defense response to virus GO:0051607 37 16 0,000 0,0477837 0,07294898 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,05069404 0,07734296 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,05069404 0,07729395 ! metencephalon development GO:0022037 30 17 0,000 0,05069404 0,077245 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,05069404 0,07719611 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,05069404 0,07714728 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,05069404 0,07709851 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,05069404 0,07704981 ! signal complex assembly GO:0007172 41 17 0,000 0,05069404 0,07700117 ! gene silencing by RNA GO:0031047 36 17 0,000 0,05069404 0,07695259 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,05069404 0,07690407 ! glial cell development GO:0021782 27 17 0,000 0,05069404 0,07685561 ! limbic system development GO:0021761 36 17 0,000 0,05069404 0,07680721 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,05069404 0,07675887 ! adult walking behavior GO:0007628 33 17 0,000 0,05069404 0,0767106 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,05069404 0,07666238 ! heart looping GO:0001947 30 17 0,000 0,05069404 0,07661423 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,05069404 0,07656613 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,05069404 0,0765181 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,05069404 0,07647012 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,05069404 0,07642221 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,05069404 0,07637436 ! glycine metabolic process GO:0006544 28 17 0,000 0,05069404 0,07632656 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,05069404 0,07627883 ! NAD metabolic process GO:0019674 29 17 0,000 0,05069404 0,07623116 ! membrane budding GO:0006900 37 17 0,000 0,05069404 0,07618354 ! DNA integration GO:0015074 29 17 0,000 0,05069404 0,07613599 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,05069404 0,07608849 ! regulation of protein binding GO:0043393 33 17 0,000 0,05069404 0,07604105 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,05069404 0,07599368 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,05069404 0,07594636 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,05069404 0,0758991 ! genitalia development GO:0048806 30 17 0,000 0,05069404 0,0758519 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,05069404 0,07580475 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,05069404 0,07575767 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,05069404 0,07571064 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,05069404 0,07566368 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,05069404 0,07561677 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,05069404 0,07556992 ! steroid catabolic process GO:0006706 31 17 0,000 0,05069404 0,07552313 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,05069404 0,07547639 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,05069404 0,07542971 ! gas transport GO:0015669 25 17 0,000 0,05069404 0,0753831 ! organic cation transport GO:0015695 31 17 0,000 0,05069404 0,07533653 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,05069404 0,07529003 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,05069404 0,07524358 ! microspike assembly GO:0030035 36 17 0,000 0,05069404 0,07519719 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,05069404 0,07515086 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,05359557 0,07940329 ! neuron maturation GO:0042551 42 18 0,000 0,05359557 0,07935442 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,05359557 0,07930562 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,05359557 0,07925688 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,05359557 0,07920819 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,05359557 0,07915957 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,05359557 0,079111 ! memory GO:0007613 31 18 0,000 0,05359557 0,0790625 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,05359557 0,07901405 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,05359557 0,07896567 ! patterning of blood vessels GO:0001569 39 18 0,000 0,05359557 0,07891734 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,05359557 0,07886907 GO:0042744|hydrogen peroxide catabolic process, ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,05359557 0,07882087 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,05359557 0,07877272 ! glutamine metabolic process GO:0006541 29 18 0,000 0,05359557 0,07872463 ! response to retinoic acid GO:0032526 26 18 0,000 0,05359557 0,07867659 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,05359557 0,07862862 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,05359557 0,07858071 ! response to fungus GO:0009620 21 18 0,000 0,05359557 0,07853285 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,05359557 0,07848505 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,05359557 0,07843731 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,05359557 0,07838963 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,05359557 0,078342 ! vitamin transport GO:0051180 27 18 0,000 0,05359557 0,07829444 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,05359557 0,07824693 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,05359557 0,07819948 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,05359557 0,07815208 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,05359557 0,07810475 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,05359557 0,07805747 ! nerve development GO:0021675 28 18 0,000 0,05359557 0,07801025 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,05359557 0,07796308 ! protein secretion GO:0009306 39 19 0,000 0,05648833 0,0821214 ! positive regulation of translation GO:0045727 30 19 0,000 0,05648833 0,08207181 ! negative regulation of defense response GO:0031348 25 19 0,000 0,05648833 0,08202228 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,05648833 0,08197281 ! skin development GO:0043588 36 19 0,000 0,05648833 0,0819234 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,05648833 0,08187405 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,05648833 0,08182476 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,05648833 0,08177552 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,05648833 0,08172635 ! bile acid metabolic process GO:0008206 29 19 0,000 0,05648833 0,08167724 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,05648833 0,08162818 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,05648833 0,08157918 ! cerebral cortex development GO:0021987 36 19 0,000 0,05648833 0,08153025 ! pigmentation during development GO:0048066 41 19 0,000 0,05648833 0,08148137 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,05648833 0,08143255 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,05648833 0,08138378 ! heme metabolic process GO:0042168 36 19 0,000 0,05648833 0,08133508 ! actin filament bundle formation GO:0051017 42 19 0,000 0,05648833 0,08128644 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,05648833 0,08123785 ! plasma membrane fusion GO:0045026 28 19 0,000 0,05648833 0,08118932 ! peptide cross-linking GO:0018149 37 19 0,000 0,05648833 0,08114085 ! protein export from nucleus GO:0006611 36 19 0,000 0,05648833 0,08109243 ! heart process GO:0003015 30 19 0,000 0,05648833 0,08104408 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,05648833 0,08099578 GO:0006692|prostanoid metabolic process, ! visual learning GO:0008542 36 19 0,000 0,05648833 0,08094754 ! cellular pigmentation GO:0033059 36 19 0,000 0,05648833 0,08089936 ! G1 phase GO:0051318 40 19 0,000 0,05648833 0,08085123 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,05648833 0,08080316 ! cell-cell junction organization GO:0045216 35 19 0,000 0,05648833 0,08075515 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,05648833 0,0807072 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,05648833 0,0806593 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,05648833 0,08061146 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,05648833 0,08056368 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,05648833 0,08051595 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,05648833 0,08046828 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,05648833 0,08042066 ! cilium assembly GO:0042384 37 19 0,000 0,05648833 0,0803731 ! peptide hormone secretion GO:0030072 31 19 0,000 0,05648833 0,0803256 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,05937234 0,08437676 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,05937234 0,08432695 ! positive regulation of ossification GO:0045778 47 20 0,000 0,05937234 0,0842772 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,05937234 0,08422751 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,05937234 0,08417788 ! cAMP metabolic process GO:0046058 36 20 0,000 0,05937234 0,0841283 ! response to vitamin GO:0033273 31 20 0,000 0,05937234 0,08407879 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,05937234 0,08402933 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,05937234 0,08397993 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,05937234 0,08393059 ! response to alkaloid GO:0043279 38 20 0,000 0,05937234 0,0838813 ! retinoid metabolic process GO:0001523 32 20 0,000 0,05937234 0,08383208 GO:0016101|diterpenoid metabolic process, ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,05937234 0,08378291 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,05937234 0,0837338 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,05937234 0,08368474 GO:0032392|DNA geometric change, ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,05937234 0,08363575 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,05937234 0,08358681 ! body fluid secretion GO:0007589 31 20 0,000 0,05937234 0,08353793 ! peptide secretion GO:0002790 35 20 0,000 0,05937234 0,08348911 ! stem cell differentiation GO:0048863 53 20 0,000 0,05937234 0,08344034 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,05937234 0,08339163 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,05937234 0,08334298 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,05937234 0,08329438 ! sensory perception of pain GO:0019233 30 20 0,000 0,05937234 0,08324584 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,05937234 0,08319736 ! diencephalon development GO:0021536 34 20 0,000 0,05937234 0,08314893 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,05937234 0,08310056 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,05937234 0,08305224 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,05937234 0,08300399 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,05937234 0,08295578 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,05937234 0,08290764 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,05937234 0,08285955 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,05937234 0,08281151 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,05937234 0,08276353 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,05937234 0,08271561 ! regulation of glucose import GO:0046324 29 20 0,000 0,05937234 0,08266774 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,05937234 0,08261993 ! actin filament-based movement GO:0030048 43 20 0,000 0,05937234 0,08257217 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,05937234 0,08252447 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,05937234 0,08247682 ! negative regulation of translation GO:0017148 29 20 0,000 0,05937234 0,08242923 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,05937234 0,0823817 ! regulation of cell killing GO:0031341 42 21 0,000 0,06224764 0,08632151 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,06224764 0,08627178 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,06224764 0,08622212 ! hormone secretion GO:0046879 38 21 0,000 0,06224764 0,08617251 ! glycerol metabolic process GO:0006071 34 21 0,000 0,06224764 0,08612295 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,06224764 0,08607346 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,06224764 0,08602402 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,06224764 0,08597464 ! axis specification GO:0009798 38 21 0,000 0,06224764 0,08592531 ! ovarian follicle development GO:0001541 35 21 0,000 0,06224764 0,08587604 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,06224764 0,08582683 ! smooth muscle contraction GO:0006939 46 21 0,000 0,06224764 0,08577767 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,06224764 0,08572857 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,06224764 0,08567953 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,06224764 0,08563054 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,06224764 0,08558161 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,06224764 0,08553273 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,06224764 0,08548391 ! cytolysis GO:0019835 24 21 0,000 0,06224764 0,08543515 ! vasodilation GO:0042311 39 21 0,000 0,06224764 0,08538644 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,06224764 0,08533779 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,06224764 0,08528919 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,06224764 0,08524065 ! oogenesis GO:0048477 36 21 0,000 0,06224764 0,08519216 ! DNA modification GO:0006304 34 21 0,000 0,06224764 0,08514373 ! collagen fibril organization GO:0030199 59 21 0,000 0,06224764 0,08509535 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,06224764 0,08504703 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,06224764 0,08499876 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,06224764 0,08495055 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,06224764 0,08490239 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,06224764 0,08485429 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,06224764 0,08480624 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,06224764 0,08475824 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,06224764 0,0847103 ! collagen catabolic process GO:0030574 28 21 0,000 0,06224764 0,08466242 ! sperm-egg recognition GO:0035036 21 21 0,000 0,06224764 0,08461459 ! gut development GO:0048565 39 21 0,000 0,06224764 0,08456681 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,06511424 0,08841132 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,06511424 0,08836146 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,06511424 0,08831165 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,06511424 0,08826189 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,06511424 0,0882122 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,06511424 0,08816255 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,06511424 0,08811297 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,06511424 0,08806344 ! regeneration GO:0031099 41 22 0,000 0,06511424 0,08801397 ! keratinization GO:0031424 28 22 0,000 0,06511424 0,08796455 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,06511424 0,08791519 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,06511424 0,08786588 ! sensory perception of taste GO:0050909 28 22 0,000 0,06511424 0,08781663 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,06511424 0,08776743 ! vacuolar transport GO:0007034 36 22 0,000 0,06511424 0,08771829 ! lysosome organization GO:0007040 41 22 0,000 0,06511424 0,0876692 ! central nervous system neuron development GO:0021954 46 22 0,000 0,06511424 0,08762017 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,06511424 0,08757119 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,06511424 0,08752227 ! fucose metabolic process GO:0006004 39 22 0,000 0,06511424 0,0874734 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,06511424 0,08742459 ! ureteric bud development GO:0001657 43 22 0,000 0,06511424 0,08737583 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,06511424 0,08732712 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,06511424 0,08727847 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,06511424 0,08722988 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,06511424 0,08718134 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,06511424 0,08713285 ! sarcomere organization GO:0045214 30 22 0,000 0,06511424 0,08708441 ! positive regulation of B cell activation GO:0050871 38 22 0,000 0,06511424 0,08703603 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,06511424 0,08698771 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,06511424 0,08693943 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,06511424 0,08689121 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,06511424 0,08684305 ! protein stabilization GO:0050821 39 22 0,000 0,06511424 0,08679494 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,06797217 0,09055429 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,06797217 0,09050418 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,06797217 0,09045412 ! gluconeogenesis GO:0006094 33 23 0,000 0,06797217 0,09040412 ! viral genome replication GO:0019079 41 23 0,000 0,06797217 0,09035417 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,06797217 0,09030428 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,06797217 0,09025444 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,06797217 0,09020466 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,06797217 0,09015493 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,06797217 0,09010526 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,06797217 0,09005564 ! visual behavior GO:0007632 42 23 0,000 0,06797217 0,09000608 ! regulation of DNA recombination GO:0000018 48 23 0,000 0,06797217 0,08995657 ! response to ethanol GO:0045471 46 23 0,000 0,06797217 0,08990712 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,06797217 0,08985772 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,06797217 0,08980837 ! peroxisome organization GO:0007031 37 23 0,000 0,06797217 0,08975908 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,06797217 0,08970984 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,06797217 0,08966066 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,06797217 0,08961153 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,06797217 0,08956246 GO:0051693|actin filament capping, ! regulation of viral reproduction GO:0050792 38 23 0,000 0,06797217 0,08951344 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,06797217 0,08946447 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,06797217 0,08941555 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,06797217 0,08936669 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,06797217 0,08931788 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,06797217 0,08926913 ! platelet activation GO:0030168 37 23 0,000 0,06797217 0,08922043 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,06797217 0,08917178 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,06797217 0,08912319 ! hormone transport GO:0009914 40 23 0,000 0,06797217 0,08907464 ! cell-cell recognition GO:0009988 25 23 0,000 0,06797217 0,08902615 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,06797217 0,08897772 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,06797217 0,08892933 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,06797217 0,088881 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,06797217 0,08883272 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,06797217 0,0887845 ! positive regulation of fibroblast proliferation GO:0048146 43 24 0,000 0,07082146 0,09245602 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,07082146 0,09240588 GO:0016444|somatic cell DNA recombination, ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,07082146 0,09235579 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,07082146 0,09230576 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,07082146 0,09225579 ! spinal cord development GO:0021510 47 24 0,000 0,07082146 0,09220587 ! vacuole organization GO:0007033 43 24 0,000 0,07082146 0,092156 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,07082146 0,09210618 ! digestive system process GO:0022600 39 24 0,000 0,07082146 0,09205642 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,07082146 0,09200672 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,07082146 0,09195706 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,07082146 0,09190747 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,07082146 0,09185792 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,07082146 0,09180843 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 47 24 0,000 0,07082146 0,09175899 ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,07082146 0,0917096 ! membrane depolarization GO:0051899 39 24 0,000 0,07082146 0,09166027 ! pallium development GO:0021543 49 24 0,000 0,07082146 0,09161099 ! pentose metabolic process GO:0019321 35 24 0,000 0,07082146 0,09156176 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,07082146 0,09151259 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,07082146 0,09146347 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,07082146 0,0914144 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,07082146 0,09136538 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,07082146 0,09131642 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,07082146 0,09126751 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,07082146 0,09121865 ! regulation of amine transport GO:0051952 40 24 0,000 0,07082146 0,09116984 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,07366214 0,09477599 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,07366214 0,09472534 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,07366214 0,09467473 ! phototransduction GO:0007602 33 25 0,000 0,07366214 0,09462419 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,07366214 0,09457369 GO:0006479|protein amino acid methylation, ! sperm motility GO:0030317 31 25 0,000 0,07366214 0,09452326 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,07366214 0,09447287 ! receptor metabolic process GO:0043112 46 25 0,000 0,07366214 0,09442254 ! chromosome condensation GO:0030261 45 25 0,000 0,07366214 0,09437226 ! osteoblast differentiation GO:0001649 60 25 0,000 0,07366214 0,09432203 ! neural crest cell development GO:0014032 54 25 0,000 0,07366214 0,09427186 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,07366214 0,09422175 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,07366214 0,09417168 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,07366214 0,09412167 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,07366214 0,09407171 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,07366214 0,09402181 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! immunoglobulin production GO:0002377 55 25 0,000 0,07366214 0,09397195 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,07366214 0,09392215 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,07366214 0,09387241 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,07366214 0,09382271 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,07366214 0,09377307 ! telomere organization GO:0032200 43 25 0,000 0,07366214 0,09372348 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,07366214 0,09367394 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,07366214 0,09362446 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,07649422 0,0971727 ! embryonic pattern specification GO:0009880 44 26 0,000 0,07649422 0,09712142 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,07649422 0,0970702 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,07649422 0,09701903 ! initiation of viral infection GO:0019059 57 26 0,000 0,07649422 0,09696791 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,07649422 0,09691685 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,07649422 0,09686584 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,07649422 0,09681489 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,07649422 0,09676398 ! tube lumen formation GO:0035148 50 26 0,000 0,07649422 0,09671314 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,07649422 0,09666234 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,07649422 0,0966116 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 0,000 0,07649422 0,09656091 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,07649422 0,09651028 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,07649422 0,0964597 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,07649422 0,09640917 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,07649422 0,09635869 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,07649422 0,09630827 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,07649422 0,0962579 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,07649422 0,09620758 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,07649422 0,09615731 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,07649422 0,0961071 ! blastocyst development GO:0001824 49 26 0,000 0,07649422 0,09605694 ! leukocyte proliferation GO:0070661 52 26 0,000 0,07649422 0,09600683 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,07649422 0,09595678 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,07649422 0,09590677 ! neuron fate commitment GO:0048663 48 27 0,000 0,07931774 0,09939505 ! iron ion transport GO:0006826 59 27 0,000 0,07931774 0,0993433 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,07931774 0,09929162 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,07931774 0,09923998 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,07931774 0,0991884 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,07931774 0,09913688 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,07931774 0,0990854 ! autophagy GO:0006914 41 27 0,000 0,07931774 0,09903398 ! male gonad development GO:0008584 44 27 0,000 0,07931774 0,09898262 ! response to toxin GO:0009636 47 27 0,000 0,07931774 0,0989313 ! primary neural tube formation GO:0014020 51 27 0,000 0,07931774 0,09888005 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,07931774 0,09882884 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,07931774 0,09877768 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,07931774 0,09872658 ! glutathione metabolic process GO:0006749 39 27 0,000 0,07931774 0,09867554 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,07931774 0,09862454 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,07931774 0,0985736 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,08213272 0,10201927 ! circadian rhythm GO:0007623 50 28 0,000 0,08213272 0,10196663 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,08213272 0,10191404 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,08213272 0,10186151 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,08213272 0,10180903 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,08213272 0,10175661 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,08213272 0,10170424 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,08213272 0,10165192 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,08213272 0,10159966 ! synaptogenesis GO:0007416 42 28 0,000 0,08213272 0,10154745 ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,08213272 0,10149529 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,08213272 0,10144319 ! translational initiation GO:0006413 65 29 0,000 0,08493919 0,10485566 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,08493919 0,10480189 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,08493919 0,10474818 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,08493919 0,10469451 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,08493919 0,10464091 ! catechol metabolic process GO:0009712 54 29 0,000 0,08493919 0,10458735 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,08493919 0,10453386 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,08493919 0,10448041 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,08493919 0,10442703 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,08493919 0,10437369 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,08493919 0,10432041 ! cell fate determination GO:0001709 60 29 0,000 0,08493919 0,10426719 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,08493919 0,10421402 ! detection of light stimulus GO:0009583 38 29 0,000 0,08493919 0,1041609 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,08493919 0,10410784 ! tissue homeostasis GO:0001894 48 29 0,000 0,08493919 0,10405483 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,08493919 0,10400188 ! phenol metabolic process GO:0018958 55 30 0,000 0,08773717 0,10737316 ! zinc ion transport GO:0006829 45 30 0,000 0,08773717 0,10731857 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,08773717 0,10726404 ! cell junction assembly GO:0034329 78 30 0,000 0,08773717 0,10720956 ! regulation of innate immune response GO:0045088 51 30 0,000 0,08773717 0,10715514 ! acute-phase response GO:0006953 49 30 0,000 0,08773717 0,10710078 ! myofibril assembly GO:0030239 47 30 0,000 0,08773717 0,10704646 GO:0055002|striated muscle cell development, ! determination of left/right symmetry GO:0007368 47 30 0,000 0,08773717 0,10699221 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,08773717 0,10693801 ! phospholipid transport GO:0015914 51 30 0,000 0,08773717 0,10688386 ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,08773717 0,10682977 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,08773717 0,10677574 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,08773717 0,10672175 ! eye morphogenesis GO:0048592 60 30 0,000 0,08773717 0,10666783 ! regulation of B cell activation GO:0050864 50 30 0,000 0,08773717 0,10661395 ! response to heat GO:0009408 50 30 0,000 0,08773717 0,10656014 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,09052669 0,10989264 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,09052669 0,10983722 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,09052669 0,10978186 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,09052669 0,10972655 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,09052669 0,1096713 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,09052669 0,10961611 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,09052669 0,10956097 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,09052669 0,10950588 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,09052669 0,10945086 ! ovulation cycle process GO:0022602 49 31 0,000 0,09052669 0,10939588 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,09052669 0,10934097 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,09052669 0,1092861 ! peptide transport GO:0015833 55 31 0,000 0,09052669 0,1092313 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,09052669 0,10917654 ! iron ion homeostasis GO:0055072 54 31 0,000 0,09052669 0,10912185 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,09052669 0,1090672 ! mesoderm formation GO:0001707 69 31 0,000 0,09052669 0,10901261 ! natural killer cell activation GO:0030101 45 31 0,000 0,09052669 0,10895808 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,09052669 0,1089036 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,09052669 0,10884918 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,09052669 0,10879481 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,09052669 0,10874049 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,09330776 0,11202519 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,09330776 0,11196932 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,09330776 0,1119135 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,09330776 0,11185774 ! cholesterol transport GO:0030301 56 32 0,000 0,09330776 0,11180203 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,09330776 0,11174638 ! spliceosome assembly GO:0000245 67 32 0,000 0,09330776 0,11169079 ! spindle organization GO:0007051 46 32 0,000 0,09330776 0,11163525 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,09330776 0,11157976 ! metanephros development GO:0001656 74 32 0,000 0,09330776 0,11152433 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,09330776 0,11146896 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,09330776 0,11141364 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,09330776 0,11135837 ! muscle cell development GO:0055001 49 32 0,000 0,09330776 0,11130316 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,09330776 0,11124801 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,09330776 0,11119291 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,09330776 0,11113786 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,09330776 0,11108287 ! ovulation cycle GO:0042698 51 32 0,000 0,09330776 0,11102793 ! BMP signaling pathway GO:0030509 64 32 0,000 0,09330776 0,11097305 ! hindbrain development GO:0030902 61 32 0,000 0,09330776 0,11091822 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,09330776 0,11086345 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,09330776 0,11080873 ! gene silencing GO:0016458 65 32 0,000 0,09330776 0,11075406 ! post-embryonic development GO:0009791 69 33 0,000 0,09608043 0,11398891 ! protein targeting to membrane GO:0006612 68 33 0,000 0,09608043 0,11393273 ! ceramide metabolic process GO:0006672 64 33 0,000 0,09608043 0,11387661 ! formation of primary germ layer GO:0001704 72 33 0,000 0,09608043 0,11382054 ! cell fate specification GO:0001708 52 33 0,000 0,09608043 0,11376453 ! sterol transport GO:0015918 57 33 0,000 0,09608043 0,11370857 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,09608043 0,11365266 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,09608043 0,11359681 ! adult locomotory behavior GO:0008344 59 33 0,000 0,09608043 0,11354102 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,09608043 0,11348528 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,09608043 0,1134296 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,09884471 0,11663579 ! glial cell differentiation GO:0010001 63 34 0,000 0,09884471 0,11657862 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,09884471 0,1165215 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,09884471 0,11646443 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,09884471 0,11640743 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,09884471 0,11635048 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,09884471 0,11629358 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,09884471 0,11623674 ! mismatch repair GO:0006298 46 34 0,000 0,09884471 0,11617996 ! spermatid development GO:0007286 63 34 0,000 0,09884471 0,11612323 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,09884471 0,11606656 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,09884471 0,11600994 ! regulation of muscle development GO:0048634 70 35 0,000 0,10160063 0,11918631 ! negative regulation of secretion GO:0051048 63 35 0,000 0,10160063 0,11912822 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,10160063 0,1190702 ! odontogenesis GO:0042476 66 35 0,000 0,10160063 0,11901223 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,10160063 0,11895431 ! female gonad development GO:0008585 58 35 0,000 0,10160063 0,11889646 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,10160063 0,11883866 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,10160063 0,11878091 ! cytokine production GO:0001816 59 35 0,000 0,10160063 0,11872322 ! neural tube formation GO:0001841 67 35 0,000 0,10160063 0,11866559 ! vesicle localization GO:0051648 64 35 0,000 0,10160063 0,11860801 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,10434821 0,12175645 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,10434821 0,12169743 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,10434821 0,12163847 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,10434821 0,12157956 ! cell junction organization GO:0034330 86 36 0,000 0,10434821 0,12152071 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,10434821 0,12146192 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,10434821 0,12140319 ! regulation of proteolysis GO:0030162 72 36 0,000 0,10434821 0,12134451 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,10434821 0,12128589 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,10434821 0,12122733 ! aerobic respiration GO:0009060 55 36 0,000 0,10434821 0,12116882 ! embryonic organ development GO:0048568 57 36 0,000 0,10434821 0,12111037 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,10434821 0,12105197 ! RNA export from nucleus GO:0006405 56 37 0,000 0,10708748 0,12416987 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,10708748 0,12411006 ! meiosis I GO:0007127 65 37 0,000 0,10708748 0,1240503 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,10708748 0,12399061 ! sister chromatid segregation GO:0000819 58 37 0,000 0,10708748 0,12393097 ! actomyosin structure organization GO:0031032 62 37 0,000 0,10708748 0,12387138 ! organic anion transport GO:0015711 68 37 0,000 0,10708748 0,12381186 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,10708748 0,12375239 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,10708748 0,12369298 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,10708748 0,12363363 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,10708748 0,12357433 GO:0015986|ATP synthesis coupled proton transport, ! glycogen metabolic process GO:0005977 61 37 0,000 0,10708748 0,12351509 ! pigment metabolic process GO:0042440 80 37 0,000 0,10708748 0,12345591 ! spermatid differentiation GO:0048515 66 37 0,000 0,10708748 0,12339678 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,10981846 0,12648311 GO:0006956|complement activation, ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,10981846 0,12642259 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,10981846 0,12636213 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,10981846 0,12630173 ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,10981846 0,12624139 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 0,000 0,10981846 0,1261811 ! lipid homeostasis GO:0055088 67 38 0,000 0,10981846 0,12612087 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,10981846 0,1260607 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,10981846 0,12600058 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,10981846 0,12594052 ! positive regulation of leukocyte proliferation GO:0070665 62 38 0,000 0,10981846 0,12588052 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,10981846 0,12582058 ! glucan metabolic process GO:0044042 62 38 0,000 0,10981846 0,1257607 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,11254118 0,12881736 ! learning GO:0007612 77 39 0,000 0,11254118 0,1287561 ! ear morphogenesis GO:0042471 60 39 0,000 0,11254118 0,12869491 ! organic ether metabolic process GO:0018904 55 39 0,000 0,11254118 0,12863377 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,11254118 0,12857269 ! ion transmembrane transport GO:0034220 66 39 0,000 0,11254118 0,12851167 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,11254118 0,12845071 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,11254118 0,1283898 ! RNA modification GO:0009451 57 39 0,000 0,11254118 0,12832895 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,11254118 0,12826816 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,11525567 0,13129978 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,11525567 0,13123764 ! feeding behavior GO:0007631 59 40 0,000 0,11525567 0,13117556 ! negative regulation of binding GO:0051100 72 40 0,000 0,11525567 0,13111354 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,11525567 0,13105157 ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,11525567 0,13098967 ! maintenance of protein location GO:0045185 91 40 0,000 0,11525567 0,13092782 ! cytokinesis GO:0000910 72 40 0,000 0,11525567 0,13086604 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,11796194 0,13387567 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,11796194 0,13381255 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,11796194 0,13374949 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,11796194 0,13368649 ! gliogenesis GO:0042063 88 41 0,000 0,11796194 0,13362355 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,11796194 0,13356067 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,11796194 0,13349784 ! female gamete generation GO:0007292 61 41 0,000 0,11796194 0,13343508 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,11796194 0,13337238 ! response to reactive oxygen species GO:0000302 67 42 0,000 0,12066002 0,13635885 ! regulation of tube size GO:0035150 71 42 0,000 0,12066002 0,13629484 GO:0050880|regulation of blood vessel size, ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,12066002 0,13623088 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,12066002 0,13616698 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,12066002 0,13610314 ! neuron migration GO:0001764 79 42 0,000 0,12066002 0,13603936 ! regulation of protein secretion GO:0050708 71 42 0,000 0,12066002 0,13597564 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,12066002 0,13591199 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,12334993 0,1388769 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,12334993 0,13881195 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,12334993 0,13874705 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,12334993 0,13868222 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,12334993 0,13861744 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,12334993 0,13855273 ! neural tube development GO:0021915 77 43 0,000 0,12334993 0,13848807 ! striated muscle contraction GO:0006941 77 43 0,000 0,12334993 0,13842348 ! phagocytosis GO:0006909 90 43 0,000 0,12334993 0,13835895 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,12334993 0,13829448 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,12603171 0,14123535 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,12603171 0,1411696 ! male sex differentiation GO:0046661 76 44 0,000 0,12603171 0,14110391 ! biopolymer methylation GO:0043414 84 44 0,000 0,12603171 0,14103828 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,12603171 0,14097271 ! maintenance of location in cell GO:0051651 97 44 0,000 0,12603171 0,1409072 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,12870538 0,1438296 ! glycolysis GO:0006096 65 45 0,000 0,12870538 0,14376283 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,12870538 0,14369612 ! leukocyte migration GO:0050900 68 45 0,000 0,12870538 0,14362947 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,12870538 0,14356288 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,12870538 0,14349636 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,12870538 0,14342989 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,12870538 0,14336349 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,12870538 0,14329715 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,12870538 0,14323087 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,12870538 0,14316465 ! cell growth GO:0016049 84 45 0,000 0,12870538 0,14309849 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,13137095 0,14599469 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,13137095 0,14592729 ! pigmentation GO:0043473 100 46 0,000 0,13137095 0,14585995 ! positive regulation of defense response GO:0031349 76 47 0,000 0,13402846 0,14874191 ! response to calcium ion GO:0051592 81 47 0,000 0,13402846 0,14867334 ! endosome transport GO:0016197 108 47 0,000 0,13402846 0,14860482 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,13402846 0,14853637 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,13402846 0,14846799 ! JNK cascade GO:0007254 91 47 0,000 0,13402846 0,14839966 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,13402846 0,1483314 ! methylation GO:0032259 90 47 0,000 0,13402846 0,1482632 ! cellular component disassembly GO:0022411 86 48 0,000 0,13667792 0,15112458 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,13667792 0,15105516 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,13667792 0,1509858 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,13667792 0,15091651 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,13667792 0,15084728 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,13931937 0,15369207 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,13931937 0,15362163 ! regulation of ion transport GO:0043269 77 49 0,000 0,13931937 0,15355126 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,13931937 0,15348095 ! peptide metabolic process GO:0006518 76 49 0,000 0,13931937 0,15341071 ! response to temperature stimulus GO:0009266 76 49 0,000 0,13931937 0,15334053 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,13931937 0,15327041 ! endocrine system development GO:0035270 104 49 0,000 0,13931937 0,15320036 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,13931937 0,15313038 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,13931937 0,15306045 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,13931937 0,1529906 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,13931937 0,1529208 ! neuromuscular process GO:0050905 99 50 0,000 0,14195282 0,1557403 ! regulation of ossification GO:0030278 117 50 0,000 0,14195282 0,15566932 ! inner ear development GO:0048839 79 50 0,000 0,14195282 0,1555984 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,14195282 0,15552754 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,14195282 0,15545675 ! viral infectious cycle GO:0019058 99 51 0,000 0,1445783 0,15825996 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,1445783 0,15818799 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,1445783 0,15811608 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,1445783 0,15804425 ! excretion GO:0007588 83 51 0,000 0,1445783 0,15797247 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,1445783 0,15790077 ! chromatin remodeling GO:0006338 109 51 0,000 0,1445783 0,15782912 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,1445783 0,15775754 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,1445783 0,15768603 ! vesicle organization GO:0016050 107 51 0,000 0,1445783 0,15761458 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,1445783 0,1575432 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,14719583 0,16032285 ! membrane fusion GO:0006944 110 52 0,000 0,14719583 0,16025031 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,14719583 0,16017783 ! amino acid activation GO:0043038 92 52 0,000 0,14719583 0,16010541 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,14719583 0,16003307 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,14980544 0,1627967 ! RNA catabolic process GO:0006401 93 53 0,000 0,14980544 0,16272321 ! regulation of translational initiation GO:0006446 82 53 0,000 0,14980544 0,16264977 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,14980544 0,16257641 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,14980544 0,16250311 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,14980544 0,16242988 ! cell maturation GO:0048469 100 53 0,000 0,14980544 0,16235671 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,14980544 0,16228361 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,15240716 0,16502773 ! cell recognition GO:0008037 85 54 0,000 0,15240716 0,1649535 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,15240716 0,16487933 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,15240716 0,16480522 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,15240716 0,16473119 ! chloride transport GO:0006821 90 55 0,000 0,155001 0,16745954 ! glucose catabolic process GO:0006007 82 55 0,000 0,155001 0,16738438 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,155001 0,16730928 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,155001 0,16723426 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,155001 0,1671593 ! gastrulation GO:0007369 112 55 0,000 0,155001 0,16708441 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,155001 0,16700958 ! RNA elongation GO:0006354 79 55 0,000 0,155001 0,16693482 ! nuclear export GO:0051168 97 55 0,000 0,155001 0,16686013 ! regulation of actin filament length GO:0030832 105 56 0,000 0,15758698 0,1695681 ! sensory perception of smell GO:0007608 80 56 0,000 0,15758698 0,1694923 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,15758698 0,16941657 ! proton transport GO:0015992 94 56 0,000 0,15758698 0,1693409 ! positive regulation of organelle organization GO:0010638 100 56 0,000 0,15758698 0,1692653 ! maintenance of location GO:0051235 118 57 0,000 0,16016514 0,17195775 ! hydrogen transport GO:0006818 97 58 0,000 0,16273549 0,17463943 ! regulation of endocytosis GO:0030100 91 58 0,000 0,16273549 0,17456157 ! adult behavior GO:0030534 99 58 0,000 0,16273549 0,17448378 ! regulation of cellular component size GO:0032535 109 59 0,000 0,16529806 0,1771524 ! skeletal system morphogenesis GO:0048705 105 59 0,000 0,16529806 0,17707353 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,16529806 0,17699472 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,16529806 0,17691599 ! DNA catabolic process GO:0006308 86 59 0,000 0,16529806 0,17683732 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,16529806 0,17675873 ! establishment of organelle localization GO:0051656 109 59 0,000 0,16529806 0,1766802 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,16785288 0,17933127 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,16785288 0,17925167 ! regulation of heart contraction GO:0008016 110 60 0,000 0,16785288 0,17917215 ! camera-type eye development GO:0043010 116 60 0,000 0,16785288 0,17909269 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,16785288 0,17901331 ! kidney development GO:0001822 122 60 0,000 0,16785288 0,17893399 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,17039996 0,18156877 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,17039996 0,1814884 ! mesoderm development GO:0007498 119 61 0,000 0,17039996 0,18140809 ! tRNA processing GO:0008033 89 61 0,000 0,17039996 0,18132786 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,17039996 0,1812477 ! ear development GO:0043583 103 62 0,000 0,17293932 0,18386744 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,17293932 0,18378622 ! gonad development GO:0008406 98 62 0,000 0,17293932 0,18370508 ! regulation of mitosis GO:0007088 105 63 0,000 0,175471 0,1863121 GO:0051783|regulation of nuclear division, ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,175471 0,18622992 ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,175471 0,18614781 ! detection of external stimulus GO:0009581 91 63 0,000 0,175471 0,18606577 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,175471 0,1859838 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,17799501 0,18857596 ! cell redox homeostasis GO:0045454 102 64 0,000 0,17799501 0,18849296 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,17799501 0,18841003 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,17799501 0,18832718 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,17799501 0,1882444 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,18051138 0,19082179 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,18051138 0,19073798 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,18051138 0,19065425 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 0,000 0,18051138 0,19057059 ! myeloid cell differentiation GO:0030099 111 65 0,000 0,18051138 0,19048701 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,18302013 0,19304973 ! actin filament organization GO:0007015 148 66 0,000 0,18302013 0,19296513 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,18302013 0,19288061 ! extracellular matrix organization GO:0030198 133 66 0,000 0,18302013 0,19279616 ! secondary metabolic process GO:0019748 116 66 0,000 0,18302013 0,19271179 ! cell projection assembly GO:0030031 120 66 0,000 0,18302013 0,19262749 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,18552128 0,19517456 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,18552128 0,19508925 ! chromosome segregation GO:0007059 113 67 0,000 0,18552128 0,19500402 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,18552128 0,19491887 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,18552128 0,19483379 ! hexose catabolic process GO:0019320 104 67 0,000 0,18552128 0,19474878 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,18552128 0,19466385 ! activation of immune response GO:0002253 105 67 0,000 0,18552128 0,19457899 ! amino acid transport GO:0006865 125 68 0,000 0,18801486 0,19710839 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,18801486 0,19702254 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,18801486 0,19693677 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,18801486 0,19685107 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,18801486 0,19676545 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,19050089 0,1992805 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,19050089 0,19919389 ! urogenital system development GO:0001655 137 69 0,000 0,19050089 0,19910736 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,19050089 0,1990209 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,19050089 0,19893452 ! antigen processing and presentation GO:0019882 104 69 0,000 0,19050089 0,19884822 ! appendage morphogenesis GO:0035107 135 70 0,000 0,19297939 0,20134797 GO:0035108|limb morphogenesis, ! amine catabolic process GO:0009310 117 71 0,000 0,19545038 0,20383772 ! reproductive structure development GO:0048608 113 71 0,000 0,19545038 0,2037494 ! appendage development GO:0048736 136 71 0,000 0,19545038 0,20366116 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,19545038 0,20357299 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,19545038 0,20348491 ! regulation of immune effector process GO:0002697 137 71 0,000 0,19545038 0,20339689 ! acute inflammatory response GO:0002526 113 72 0,000 0,19791389 0,20587152 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 0,000 0,19791389 0,20578255 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,19791389 0,20569366 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,19791389 0,20560484 ! learning or memory GO:0007611 147 73 0,000 0,20036994 0,20806649 ! regulation of blood pressure GO:0008217 125 73 0,000 0,20036994 0,20797673 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,20036994 0,20788705 ! fertilization GO:0009566 90 73 0,000 0,20036994 0,20779744 ! transition metal ion transport GO:0000041 126 74 0,000 0,20281854 0,21024619 ! neurotransmitter transport GO:0006836 123 74 0,000 0,20281854 0,21015565 ! meiosis GO:0007126 121 74 0,000 0,20281854 0,21006518 GO:0051327|M phase of meiotic cell cycle, ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,20281854 0,20997479 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,20281854 0,20988448 ! eye development GO:0001654 143 74 0,000 0,20281854 0,20979425 ! organelle localization GO:0051640 136 74 0,000 0,20281854 0,20970409 ! cell-matrix adhesion GO:0007160 163 75 0,000 0,20525973 0,21213699 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,20525973 0,21204591 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,20525973 0,2119549 ! meiotic cell cycle GO:0051321 122 75 0,000 0,20525973 0,21186397 ! rhythmic process GO:0048511 128 75 0,000 0,20525973 0,21177312 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,20769353 0,2141923 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,20769353 0,21410053 ! defense response to bacterium GO:0042742 89 76 0,000 0,20769353 0,21400884 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,20769353 0,21391722 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,20769353 0,21382569 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,21011995 0,21623123 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,21011995 0,21613878 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,21011995 0,21604641 ! positive regulation of lymphocyte activation GO:0051251 127 77 0,000 0,21011995 0,21595413 ! blood coagulation GO:0007596 146 78 0,000 0,21253903 0,2183471 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,21253903 0,21825391 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,21253903 0,21816079 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,21495077 0,22054224 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,21495077 0,22044823 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 0,000 0,21495077 0,22035431 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,21495077 0,22026046 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,21735521 0,22262948 ! response to metal ion GO:0010038 140 80 0,000 0,21735521 0,22253474 ! inorganic anion transport GO:0015698 138 80 0,000 0,21735521 0,22244008 ! digestion GO:0007586 112 81 0,000 0,21975237 0,2247977 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,21975237 0,22470216 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,21975237 0,22460671 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,22214226 0,22695298 ! response to nutrient GO:0007584 125 82 0,000 0,22214226 0,22685665 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,22214226 0,2267604 ! regulation of lyase activity GO:0051339 160 83 0,000 0,22452491 0,22909539 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,22690034 0,23142103 ! hemostasis GO:0007599 158 84 0,000 0,22690034 0,23132297 ! negative regulation of transport GO:0051051 153 84 0,000 0,22690034 0,231225 ! regulation of ligase activity GO:0051340 142 84 0,000 0,22690034 0,2311271 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,22690034 0,23102929 ! response to unfolded protein GO:0006986 131 85 0,000 0,22926857 0,23334187 ! nucleosome assembly GO:0006334 122 85 0,000 0,22926857 0,23324321 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,22926857 0,23314463 ! positive regulation of cell activation GO:0050867 145 85 0,000 0,22926857 0,23304613 GO:0002696|positive regulation of leukocyte activation, ! amine biosynthetic process GO:0009309 138 86 0,000 0,23162963 0,23534666 ! response to inorganic substance GO:0010035 153 86 0,000 0,23162963 0,23524732 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,23162963 0,23514806 ! chromatin assembly GO:0031497 124 86 0,000 0,23162963 0,23504888 ! tube morphogenesis GO:0035239 176 86 0,000 0,23162963 0,23494979 ! alcohol catabolic process GO:0046164 130 86 0,000 0,23162963 0,23485078 ! amine transport GO:0015837 155 86 0,000 0,23162963 0,23475185 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,23398353 0,23703764 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,23398353 0,23693787 ! cellular respiration GO:0045333 135 88 0,000 0,2363303 0,23921359 ! positive regulation of protein modification process GO:0031401 136 88 0,000 0,2363303 0,239113 ! regulation of neurological system process GO:0031644 148 88 0,000 0,2363303 0,23901249 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,2363303 0,23891206 ! cellular defense response GO:0006968 114 89 0,000 0,23866996 0,24117595 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,24100253 0,24343077 ! regulation of cell cycle process GO:0010564 149 90 0,000 0,24100253 0,24332862 ! sex differentiation GO:0007548 145 90 0,000 0,24100253 0,24322655 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,24100253 0,24312457 ! response to protein stimulus GO:0051789 149 91 0,000 0,24332803 0,24536766 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,24332803 0,24526487 ! regulation of defense response GO:0031347 149 92 0,000 0,24564648 0,24749809 ! nucleosome organization GO:0034728 138 92 0,000 0,24564648 0,24739449 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,24564648 0,24729098 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,24795791 0,24951348 GO:0010498|proteasomal protein catabolic process, ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,24795791 0,24940917 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,24795791 0,24930494 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,25026233 0,25151677 ! transcription initiation GO:0006352 153 94 0,000 0,25026233 0,25141176 ! forebrain development GO:0030900 188 95 0,000 0,25255976 0,25361385 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,25255976 0,25350804 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,25485023 0,25570044 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,25485023 0,25559385 ! positive regulation of immune response GO:0050778 156 96 0,000 0,25485023 0,25548736 ! detection of stimulus GO:0051606 151 96 0,000 0,25485023 0,25538095 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,25713376 0,25756196 ! hormone metabolic process GO:0042445 157 97 0,000 0,25713376 0,25745477 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,25941036 0,25962618 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,26168007 0,26178887 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,26168007 0,26168007