pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6642-VanDeVijver-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/vantveer-oligo_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! positive regulation of protein kinase activity GO:0045860 89 86 4,000 7,651E-06 0,01410105 ! positive regulation of transferase activity GO:0051347 91 88 4,000 8,569E-06 7,896E-03 GO:0033674|positive regulation of kinase activity, ! positive regulation of epithelial cell proliferation GO:0050679 14 14 2,000 1,16E-05 7,126E-03 ! positive regulation of MAP kinase activity GO:0043406 50 49 3,000 1,821E-05 8,389E-03 ! multicellular organismal metabolic process GO:0044236 19 19 2,000 3,055E-05 0,01125909 ! regulation of MAP kinase activity GO:0043405 67 66 3,000 5,964E-05 0,01832006 ! protein amino acid autophosphorylation GO:0046777 28 28 2,000 1,013E-04 0,02666036 ! 2-oxoglutarate metabolic process GO:0006103 5 5 1,000 1,063E-04 0,02448036 ! insulin-like growth factor receptor signaling pathway GO:0048009 5 5 1,000 1,063E-04 0,02176032 ! regulation of phospholipase A2 activity GO:0032429 5 5 1,000 1,063E-04 0,01958429 ! DNA methylation GO:0006306 5 5 1,000 1,063E-04 0,0178039 GO:0006305|DNA alkylation, ! positive regulation of cell cycle GO:0045787 29 29 2,000 1,127E-04 0,01730852 ! regulation of epithelial cell proliferation GO:0050678 29 29 2,000 1,127E-04 0,01597709 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 32 32 2,000 1,52E-04 0,02000708 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 6 6 1,000 1,591E-04 0,01954444 ! succinate metabolic process GO:0006105 7 6 1,000 1,591E-04 0,01832292 ! pathogenesis GO:0009405 6 6 1,000 1,591E-04 0,0172451 ! negative regulation of T cell proliferation GO:0042130 6 6 1,000 1,591E-04 0,01628704 GO:0070667|negative regulation of mast cell proliferation, ! regulation of T cell differentiation in the thymus GO:0033081 6 6 1,000 1,591E-04 0,01542982 ! phosphoinositide 3-kinase cascade GO:0014065 6 6 1,000 1,591E-04 0,01465833 ! localization within membrane GO:0051668 6 6 1,000 1,591E-04 0,01396032 ! activation of protein kinase activity GO:0032147 35 33 2,000 1,668E-04 0,01397443 ! positive regulation of phosphorylation GO:0042327 35 35 2,000 1,992E-04 0,01596502 ! positive regulation of phosphorus metabolic process GO:0010562 36 36 2,000 2,169E-04 0,01665434 GO:0045937|positive regulation of phosphate metabolic process, ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 7 7 1,000 2,222E-04 0,01638393 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 7 7 1,000 2,222E-04 0,01575378 ! oxaloacetate metabolic process GO:0006107 7 7 1,000 2,222E-04 0,01517031 ! regulation of mRNA processing GO:0050684 7 7 1,000 2,222E-04 0,01462851 ! negative regulation of lymphocyte proliferation GO:0050672 7 7 1,000 2,222E-04 0,01412408 GO:0032945|negative regulation of mononuclear cell proliferation, GO:0070664|negative regulation of leukocyte proliferation, ! negative regulation of T cell activation GO:0050868 7 7 1,000 2,222E-04 0,01365328 ! zinc ion transport GO:0006829 8 8 1,000 2,957E-04 0,0175813 ! phosphagen metabolic process GO:0006599 8 8 1,000 2,957E-04 0,01703189 GO:0006600|creatine metabolic process, ! branched chain family amino acid metabolic process GO:0009081 8 8 1,000 2,957E-04 0,01651577 ! regulation of nitric-oxide synthase activity GO:0050999 9 9 1,000 3,794E-04 0,0205681 ! collagen catabolic process GO:0030574 9 9 1,000 3,794E-04 0,01998044 ! mRNA transport GO:0051028 44 44 2,000 3,953E-04 0,02023855 ! negative regulation of nucleocytoplasmic transport GO:0046823 10 10 1,000 4,733E-04 0,02357748 ! neuromuscular junction development GO:0007528 10 10 1,000 4,733E-04 0,02295702 ! histone deacetylation GO:0016575 10 10 1,000 4,733E-04 0,02236838 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 11 11 1,000 5,774E-04 0,02660146 ! activation of MAPKK activity GO:0000186 12 11 1,000 5,774E-04 0,02595264 ! positive regulation of nitric oxide biosynthetic process GO:0045429 11 11 1,000 5,774E-04 0,02533472 ! regulation of monooxygenase activity GO:0032768 11 11 1,000 5,774E-04 0,02474554 ! negative regulation of lymphocyte activation GO:0051250 11 11 1,000 5,774E-04 0,02418314 ! RNA transport GO:0050658 50 50 2,000 5,774E-04 0,02364963 GO:0050657|nucleic acid transport, GO:0051236|establishment of RNA localization, ! RNA localization GO:0006403 52 52 2,000 6,483E-04 0,02597297 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 53 53 2,000 6,857E-04 0,02688689 ! positive regulation of protein catabolic process GO:0045732 12 12 1,000 6,914E-04 0,02654738 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 12 12 1,000 6,914E-04 0,0260056 ! collagen metabolic process GO:0032963 12 12 1,000 6,914E-04 0,02548549 ! positive regulation of multicellular organism growth GO:0040018 12 12 1,000 6,914E-04 0,02498577 ! positive regulation of JAK-STAT cascade GO:0046427 13 13 1,000 8,155E-04 0,02890192 ! regulation of nitric oxide biosynthetic process GO:0045428 13 13 1,000 8,155E-04 0,0283566 ! multicellular organismal macromolecule metabolic process GO:0044259 13 13 1,000 8,155E-04 0,02783148 ! multicellular organismal catabolic process GO:0044243 13 13 1,000 8,155E-04 0,02732545 ! negative regulation of intracellular transport GO:0032387 13 13 1,000 8,155E-04 0,02683749 ! negative regulation of leukocyte activation GO:0002695 13 13 1,000 8,155E-04 0,02636666 ! tissue homeostasis GO:0001894 13 13 1,000 8,155E-04 0,02591206 GO:0048871|multicellular organismal homeostasis, ! protein amino acid deacetylation GO:0006476 14 14 1,000 9,494E-04 0,02965796 ! DNA modification GO:0006304 14 14 1,000 9,494E-04 0,02916366 ! regulation of protein amino acid phosphorylation GO:0001932 62 61 2,000 1,035E-03 0,03127658 ! negative regulation of cell activation GO:0050866 15 15 1,000 1,093E-03 0,03249872 ! positive regulation of protein metabolic process GO:0051247 64 64 2,000 1,191E-03 0,03482958 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 16 16 1,000 1,247E-03 0,03590762 ! cellular response to reactive oxygen species GO:0034614 16 16 1,000 1,247E-03 0,0353552 ! positive regulation of catabolic process GO:0009896 16 16 1,000 1,247E-03 0,03481951 ! positive regulation of cell adhesion GO:0045785 17 17 1,000 1,41E-03 0,03879417 ! myelination GO:0042552 17 17 1,000 1,41E-03 0,03822366 ! dicarboxylic acid metabolic process GO:0043648 18 17 1,000 1,41E-03 0,0376697 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 17 17 1,000 1,41E-03 0,03713156 ! regulation of oxidoreductase activity GO:0051341 17 17 1,000 1,41E-03 0,03660858 ! epidermal growth factor receptor signaling pathway GO:0007173 18 18 1,000 1,583E-03 0,04053016 ! ensheathment of neurons GO:0007272 18 18 1,000 1,583E-03 0,03997495 GO:0008366|axon ensheathment, ! symbiosis, encompassing mutualism through parasitism GO:0044403 18 18 1,000 1,583E-03 0,03943475 ! regulation of JAK-STAT cascade GO:0046425 19 19 1,000 1,766E-03 0,04339817 ! peptidyl-tyrosine phosphorylation GO:0018108 20 19 1,000 1,766E-03 0,04282714 ! cellular response to oxidative stress GO:0034599 19 19 1,000 1,766E-03 0,04227095 ! nuclear-transcribed mRNA catabolic process GO:0000956 19 19 1,000 1,766E-03 0,04172901 ! peripheral nervous system development GO:0007422 19 19 1,000 1,766E-03 0,0412008 ! peptidyl-tyrosine modification GO:0018212 21 20 1,000 1,958E-03 0,04511464 ! single fertilization GO:0007338 21 20 1,000 1,958E-03 0,04455767 ! regulation of protein modification process GO:0031399 79 78 2,000 2,109E-03 0,04739316 ! mRNA catabolic process GO:0006402 21 21 1,000 2,16E-03 0,04796369 ! G1/S transition of mitotic cell cycle GO:0000082 21 21 1,000 2,16E-03 0,04739269 ! mammary gland development GO:0030879 23 21 1,000 2,16E-03 0,04683513 ! regulation of action potential in neuron GO:0019228 21 21 1,000 2,16E-03 0,04629054 ! regulation of multicellular organism growth GO:0040014 21 21 1,000 2,16E-03 0,04575846 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 21 21 1,000 2,16E-03 0,04523848 ! negative regulation of protein transport GO:0051224 21 21 1,000 2,16E-03 0,04473018 ! MAPKKK cascade GO:0000165 82 81 2,000 2,349E-03 0,04811192 ! cellular amide metabolic process GO:0043603 22 22 1,000 2,371E-03 0,04802413 ! biopolymer methylation GO:0043414 22 22 1,000 2,371E-03 0,04750213 GO:0032259|methylation, ! neuron migration GO:0001764 22 22 1,000 2,371E-03 0,04699136 ! positive regulation of growth GO:0045927 23 23 1,000 2,592E-03 0,05081587 ! calcium-mediated signaling GO:0019722 23 23 1,000 2,592E-03 0,05028096 ! regulation of action potential GO:0001508 24 24 1,000 2,822E-03 0,05417044 ! fertilization GO:0009566 25 24 1,000 2,822E-03 0,05361199 ! regulation of intracellular protein transport GO:0033157 25 25 1,000 3,061E-03 0,05756224 ! regulation of T cell proliferation GO:0042129 25 25 1,000 3,061E-03 0,05698081 ! positive regulation of DNA binding GO:0043388 26 25 1,000 3,061E-03 0,056411 ! negative regulation of immune system process GO:0002683 25 25 1,000 3,061E-03 0,05585247 ! JAK-STAT cascade GO:0007259 26 25 1,000 3,061E-03 0,0553049 ! positive regulation of binding GO:0051099 27 26 1,000 3,309E-03 0,0592116 ! regulation of T cell differentiation GO:0045580 26 26 1,000 3,309E-03 0,05864226 ! synapse organization GO:0050808 26 26 1,000 3,309E-03 0,05808376 ! regulation of nucleocytoplasmic transport GO:0046822 27 27 1,000 3,567E-03 0,06201263 ! tRNA aminoacylation for protein translation GO:0006418 28 28 1,000 3,833E-03 0,06602453 GO:0043038|amino acid activation, GO:0043039|tRNA aminoacylation, ! histone modification GO:0016570 28 28 1,000 3,833E-03 0,06541319 ! regulation of mast cell proliferation GO:0070666 28 28 1,000 3,833E-03 0,06481307 ! viral reproductive process GO:0022415 29 29 1,000 4,109E-03 0,06884132 ! regulation of lymphocyte proliferation GO:0050670 29 29 1,000 4,109E-03 0,06822113 GO:0032944|regulation of mononuclear cell proliferation, GO:0070663|regulation of leukocyte proliferation, ! regulation of gene expression, epigenetic GO:0040029 29 29 1,000 4,109E-03 0,06761201 ! covalent chromatin modification GO:0016569 29 29 1,000 4,109E-03 0,06701367 ! response to UV GO:0009411 29 29 1,000 4,109E-03 0,06642584 ! transition metal ion transport GO:0000041 31 30 1,000 4,393E-03 0,07040863 ! RNA catabolic process GO:0006401 30 30 1,000 4,393E-03 0,06980166 ! response to reactive oxygen species GO:0000302 31 30 1,000 4,393E-03 0,06920507 ! activation of phospholipase C activity GO:0007202 30 30 1,000 4,393E-03 0,06861858 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of protein amino acid phosphorylation GO:0001934 30 30 1,000 4,393E-03 0,06804196 ! skeletal muscle fiber development GO:0048741 31 31 1,000 4,687E-03 0,07198218 ! positive regulation of phospholipase activity GO:0010518 31 31 1,000 4,687E-03 0,07138729 ! regulation of intracellular transport GO:0032386 31 31 1,000 4,687E-03 0,07080215 ! muscle fiber development GO:0048747 32 32 1,000 4,989E-03 0,07475647 ! positive regulation of lipase activity GO:0060193 32 32 1,000 4,989E-03 0,0741536 ! regulation of phospholipase activity GO:0010517 32 32 1,000 4,989E-03 0,07356037 ! regulation of lymphocyte differentiation GO:0045619 32 32 1,000 4,989E-03 0,07297656 ! regulation of protein complex assembly GO:0043254 33 33 1,000 5,3E-03 0,07691685 ! regulation of angiogenesis GO:0045765 35 34 1,000 5,62E-03 0,0809214 ! regulation of protein catabolic process GO:0042176 35 34 1,000 5,62E-03 0,0802941 ! viral reproduction GO:0016032 34 34 1,000 5,62E-03 0,07967645 ! regulation of cyclin-dependent protein kinase activity GO:0000079 35 35 1,000 5,949E-03 0,08369037 ! positive regulation of cell migration GO:0030335 36 36 1,000 6,286E-03 0,0877639 ! regulation of lipase activity GO:0060191 36 36 1,000 6,286E-03 0,08710402 ! negative regulation of protein kinase activity GO:0006469 37 37 1,000 6,632E-03 0,09120913 ! response to drug GO:0042493 37 37 1,000 6,632E-03 0,09053351 ! negative regulation of kinase activity GO:0033673 38 38 1,000 6,986E-03 0,09466841 ! axon guidance GO:0007411 39 38 1,000 6,986E-03 0,0939774 ! positive regulation of protein modification process GO:0031401 39 39 1,000 7,349E-03 0,09814036 ! activation of MAPK activity GO:0000187 39 39 1,000 7,349E-03 0,09743431 ! intracellular protein transmembrane transport GO:0065002 39 39 1,000 7,349E-03 0,09673835 ! positive regulation of cell motion GO:0051272 39 39 1,000 7,349E-03 0,09605227 ! negative regulation of transferase activity GO:0051348 40 40 1,000 7,72E-03 0,1001924 ! protein ubiquitination GO:0016567 43 42 1,000 8,487E-03 0,10937954 ! forebrain development GO:0030900 43 42 1,000 8,487E-03 0,10861996 ! one-carbon metabolic process GO:0006730 42 42 1,000 8,487E-03 0,10787086 ! protein import into nucleus GO:0006606 44 44 1,000 9,287E-03 0,11723256 ! regulation of DNA binding GO:0051101 47 45 1,000 9,699E-03 0,12160418 ! phosphoinositide-mediated signaling GO:0048015 45 45 1,000 9,699E-03 0,12078253 ! nuclear import GO:0051170 45 45 1,000 9,699E-03 0,11997191 ! cellular response to hormone stimulus GO:0032870 48 46 1,000 0,01011967 0,12433706 ! regulation of membrane potential GO:0042391 46 46 1,000 0,01011967 0,12351363 ! regulation of catabolic process GO:0009894 48 47 1,000 0,01054807 0,1278953 ! protein localization in nucleus GO:0034504 48 48 1,000 0,01098443 0,13231566 ! ossification GO:0001503 50 49 1,000 0,0114287 0,13677333 GO:0060348|bone development, ! gland development GO:0048732 51 49 1,000 0,0114287 0,13589092 ! cell cycle arrest GO:0007050 49 49 1,000 0,0114287 0,13501983 ! skeletal muscle tissue development GO:0007519 50 49 1,000 0,0114287 0,13415983 GO:0060538|skeletal muscle organ development, ! negative regulation of transport GO:0051051 51 50 1,000 0,01188083 0,13858468 ! anatomical structure homeostasis GO:0060249 51 50 1,000 0,01188083 0,13771307 ! protein modification by small protein conjugation GO:0032446 52 51 1,000 0,01234078 0,14215035 ! interphase of mitotic cell cycle GO:0051329 52 51 1,000 0,01234078 0,14126743 GO:0051325|interphase, ! ATP biosynthetic process GO:0006754 51 51 1,000 0,01234078 0,14039541 ! response to light stimulus GO:0009416 53 52 1,000 0,01280848 0,14482226 ! sodium ion transport GO:0006814 53 53 1,000 0,01328388 0,1492817 ! tRNA metabolic process GO:0006399 53 53 1,000 0,01328388 0,14837696 ! response to hypoxia GO:0001666 53 53 1,000 0,01328388 0,14748312 ! regulation of T cell activation GO:0050863 53 53 1,000 0,01328388 0,14659999 ! regulation of protein transport GO:0051223 53 53 1,000 0,01328388 0,14572737 GO:0070201|regulation of establishment of protein localization, ! response to oxygen levels GO:0070482 55 54 1,000 0,01376694 0,15013297 ! sulfur metabolic process GO:0006790 55 54 1,000 0,01376694 0,14924983 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 55 55 1,000 0,0142576 0,15366521 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! regulation of cell adhesion GO:0030155 56 55 1,000 0,0142576 0,15277181 ! protein modification by small protein conjugation or removal GO:0070647 56 55 1,000 0,0142576 0,15188873 ! ribonucleoside triphosphate biosynthetic process GO:0009201 56 56 1,000 0,0147558 0,15629278 ! extracellular structure organization GO:0043062 56 56 1,000 0,0147558 0,15539967 ! regulation of binding GO:0051098 60 57 1,000 0,0152615 0,15981223 ! ATP metabolic process GO:0046034 57 57 1,000 0,0152615 0,15890933 ! nucleoside triphosphate biosynthetic process GO:0009142 57 57 1,000 0,0152615 0,15801658 ! regulation of protein localization GO:0032880 58 57 1,000 0,0152615 0,15713381 ! peptidyl-amino acid modification GO:0018193 61 59 1,000 0,0162952 0,1668447 ! protein localization in organelle GO:0033365 59 59 1,000 0,0162952 0,16592291 ! rRNA transcription GO:0009303 5 5 0,000 0,01660853 0,16818416 ! positive regulation of protein ubiquitination GO:0031398 5 5 0,000 0,01660853 0,16726512 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 5 5 0,000 0,01660853 0,16635607 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 5 5 0,000 0,01660853 0,16545685 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! neuron fate specification GO:0048665 5 5 0,000 0,01660853 0,16456729 ! hemoglobin biosynthetic process GO:0042541 5 5 0,000 0,01660853 0,16368725 ! reproductive cellular process GO:0048610 5 5 0,000 0,01660853 0,16281658 ! positive regulation of glucose metabolic process GO:0010907 5 5 0,000 0,01660853 0,16195511 ! negative regulation of blood pressure GO:0045776 6 5 0,000 0,01660853 0,16110272 ! prostate gland development GO:0030850 5 5 0,000 0,01660853 0,16025925 ! metencephalon development GO:0022037 5 5 0,000 0,01660853 0,15942457 ! water transport GO:0006833 5 5 0,000 0,01660853 0,15859853 GO:0042044|fluid transport, ! forebrain regionalization GO:0021871 5 5 0,000 0,01660853 0,15778101 ! DNA synthesis during DNA repair GO:0000731 5 5 0,000 0,01660853 0,15697188 ! positive regulation of B cell proliferation GO:0030890 5 5 0,000 0,01660853 0,156171 ! glycerol metabolic process GO:0006071 5 5 0,000 0,01660853 0,15537826 ! regulation of cellular amine metabolic process GO:0033238 5 5 0,000 0,01660853 0,15459352 GO:0042053|regulation of dopamine metabolic process, GO:0042069|regulation of catecholamine metabolic process, ! meiotic prophase I GO:0007128 5 5 0,000 0,01660853 0,15381667 GO:0051324|prophase, ! cell volume homeostasis GO:0006884 5 5 0,000 0,01660853 0,15304758 ! regulation of epidermal growth factor receptor activity GO:0007176 5 5 0,000 0,01660853 0,15228615 GO:0010469|regulation of receptor activity, ! regulation of long-term neuronal synaptic plasticity GO:0048169 5 5 0,000 0,01660853 0,15153226 ! filopodium assembly GO:0046847 7 5 0,000 0,01660853 0,1507858 GO:0030035|microspike assembly, ! CTP metabolic process GO:0046036 5 5 0,000 0,01660853 0,15004665 GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0006241|CTP biosynthetic process, ! Golgi to endosome transport GO:0006895 5 5 0,000 0,01660853 0,14931471 ! GTP metabolic process GO:0046039 5 5 0,000 0,01660853 0,14858989 ! establishment of tissue polarity GO:0007164 5 5 0,000 0,01660853 0,14787206 ! mRNA stabilization GO:0048255 5 5 0,000 0,01660853 0,14716114 GO:0043489|RNA stabilization, ! positive regulation of cell-cell adhesion GO:0022409 5 5 0,000 0,01660853 0,14645702 ! regulation of neurotransmitter secretion GO:0046928 5 5 0,000 0,01660853 0,1457596 GO:0001956|positive regulation of neurotransmitter secretion, ! neurotransmitter uptake GO:0001504 5 5 0,000 0,01660853 0,1450688 ! social behavior GO:0035176 5 5 0,000 0,01660853 0,14438451 ! macrophage chemotaxis GO:0048246 6 5 0,000 0,01660853 0,14370665 ! memory GO:0007613 5 5 0,000 0,01660853 0,14303512 ! dopamine receptor signaling pathway GO:0007212 5 5 0,000 0,01660853 0,14236984 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 5 5 0,000 0,01660853 0,14171072 ! membrane hyperpolarization GO:0060081 5 5 0,000 0,01660853 0,14105768 ! response to lipid GO:0033993 5 5 0,000 0,01660853 0,14041063 ! erythrocyte maturation GO:0043249 5 5 0,000 0,01660853 0,13976948 ! hippocampus development GO:0021766 6 5 0,000 0,01660853 0,13913417 ! regulation of carbohydrate biosynthetic process GO:0043255 5 5 0,000 0,01660853 0,1385046 ! glucocorticoid metabolic process GO:0008211 5 5 0,000 0,01660853 0,13788071 ! middle ear morphogenesis GO:0042474 5 5 0,000 0,01660853 0,13726241 ! amyloid precursor protein catabolic process GO:0042987 5 5 0,000 0,01660853 0,13664963 ! mechanosensory behavior GO:0007638 5 5 0,000 0,01660853 0,1360423 ! heart looping GO:0001947 5 5 0,000 0,01660853 0,13544034 ! negative regulation of endocytosis GO:0045806 5 5 0,000 0,01660853 0,13484369 ! response to interferon-gamma GO:0034341 5 5 0,000 0,01660853 0,13425227 ! pseudouridine synthesis GO:0001522 5 5 0,000 0,01660853 0,13366601 ! endocrine pancreas development GO:0031018 5 5 0,000 0,01660853 0,13308485 ! pH reduction GO:0045851 5 5 0,000 0,01660853 0,13250873 GO:0051452|intracellular pH reduction, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 5 5 0,000 0,01660853 0,13193757 ! lipopolysaccharide metabolic process GO:0008653 5 5 0,000 0,01660853 0,13137132 ! positive regulation of chemokine biosynthetic process GO:0045080 5 5 0,000 0,01660853 0,1308099 ! sphingoid biosynthetic process GO:0046520 5 5 0,000 0,01660853 0,13025326 GO:0046513|ceramide biosynthetic process, ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 5 5 0,000 0,01660853 0,12970134 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! thymic T cell selection GO:0045061 5 5 0,000 0,01660853 0,12915408 ! photoreceptor cell maintenance GO:0045494 5 5 0,000 0,01660853 0,12861141 ! adrenal gland development GO:0030325 5 5 0,000 0,01660853 0,12807329 ! regulation of cardiac muscle hypertrophy GO:0010611 5 5 0,000 0,01660853 0,12753965 GO:0010612|regulation of cardiac muscle adaptation, GO:0014743|regulation of muscle hypertrophy, GO:0043502|regulation of muscle adaptation, ! melanocyte differentiation GO:0030318 5 5 0,000 0,01660853 0,12701044 GO:0050931|pigment cell differentiation, ! ovulation GO:0030728 5 5 0,000 0,01660853 0,12648561 ! astrocyte differentiation GO:0048708 5 5 0,000 0,01660853 0,12596509 ! mitochondrial respiratory chain complex assembly GO:0033108 5 5 0,000 0,01660853 0,12544884 GO:0032981|mitochondrial respiratory chain complex I assembly, GO:0010257|NADH dehydrogenase complex assembly, ! pituitary gland development GO:0021983 5 5 0,000 0,01660853 0,1249368 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 5 5 0,000 0,01660853 0,12442893 GO:0033135|regulation of peptidyl-serine phosphorylation, ! tyrosine metabolic process GO:0006570 5 5 0,000 0,01660853 0,12392517 ! cytoskeletal anchoring at plasma membrane GO:0007016 6 5 0,000 0,01660853 0,12342547 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 5 5 0,000 0,01660853 0,12292979 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, GO:0009164|nucleoside catabolic process, ! microtubule nucleation GO:0007020 5 5 0,000 0,01660853 0,12243807 ! regulation of interleukin-6 biosynthetic process GO:0045408 5 5 0,000 0,01660853 0,12195027 ! regulation of interleukin-8 biosynthetic process GO:0045414 5 5 0,000 0,01660853 0,12146634 ! indolalkylamine metabolic process GO:0006586 5 5 0,000 0,01660853 0,12098623 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! muscle cell migration GO:0014812 5 5 0,000 0,01660853 0,12050991 ! phasic smooth muscle contraction GO:0014821 5 5 0,000 0,01660853 0,12003732 ! central nervous system neuron axonogenesis GO:0021955 6 5 0,000 0,01660853 0,11956842 GO:0021952|central nervous system projection neuron axonogenesis, ! sister chromatid cohesion GO:0007062 5 5 0,000 0,01660853 0,11910318 ! response to ATP GO:0033198 5 5 0,000 0,01660853 0,11864154 ! regulation of type I interferon production GO:0032479 5 5 0,000 0,01660853 0,11818346 ! regulation of appetite GO:0032098 5 5 0,000 0,01660853 0,11772891 GO:0032095|regulation of response to food, ! vesicle fusion GO:0006906 5 5 0,000 0,01660853 0,11727784 ! paraxial mesoderm development GO:0048339 5 5 0,000 0,01660853 0,11683022 ! regulation of the force of heart contraction GO:0002026 5 5 0,000 0,01660853 0,11638599 ! maintenance of protein location in nucleus GO:0051457 5 5 0,000 0,01660853 0,11594514 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,01660853 0,11550761 ! receptor clustering GO:0043113 5 5 0,000 0,01660853 0,11507337 ! neurotransmitter biosynthetic process GO:0042136 6 5 0,000 0,01660853 0,11464238 ! fear response GO:0042596 5 5 0,000 0,01660853 0,11421461 ! actin cytoskeleton reorganization GO:0031532 5 5 0,000 0,01660853 0,11379002 ! lens development in camera-type eye GO:0002088 5 5 0,000 0,01660853 0,11336858 ! retinol metabolic process GO:0042572 5 5 0,000 0,01660853 0,11295025 ! corticosteroid receptor signaling pathway GO:0031958 5 5 0,000 0,01660853 0,11253499 GO:0042921|glucocorticoid receptor signaling pathway, ! temperature homeostasis GO:0001659 5 5 0,000 0,01660853 0,11212277 ! positive regulation of exocytosis GO:0045921 6 5 0,000 0,01660853 0,11171356 ! parturition GO:0007567 5 5 0,000 0,01660853 0,11130733 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,01660853 0,11090405 ! regulation of vascular endothelial growth factor production GO:0010574 5 5 0,000 0,01660853 0,11050367 ! Schwann cell differentiation GO:0014037 5 5 0,000 0,01660853 0,11010617 ! acyl-CoA metabolic process GO:0006637 5 5 0,000 0,01660853 0,10971153 ! wound healing, spreading of epidermal cells GO:0035313 5 5 0,000 0,01660853 0,1093197 ! protein heterooligomerization GO:0051291 5 5 0,000 0,01660853 0,10893066 ! regulation of gliogenesis GO:0014013 5 5 0,000 0,01660853 0,10854438 GO:0045685|regulation of glial cell differentiation, ! positive regulation of peptide secretion GO:0002793 5 5 0,000 0,01660853 0,10816084 ! response to UV-B GO:0010224 5 5 0,000 0,01660853 0,10777999 ! oligodendrocyte development GO:0014003 5 5 0,000 0,01660853 0,10740181 ! hyaluronan metabolic process GO:0030212 5 5 0,000 0,01660853 0,10702628 ! activated T cell proliferation GO:0050798 5 5 0,000 0,01660853 0,10665337 ! interaction with symbiont GO:0051702 5 5 0,000 0,01660853 0,10628304 ! cellular extravasation GO:0045123 5 5 0,000 0,01660853 0,10591528 ! positive regulation of axonogenesis GO:0050772 5 5 0,000 0,01660853 0,10555006 ! peptidyl-asparagine modification GO:0018196 5 5 0,000 0,01660853 0,10518734 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! positive regulation of phagocytosis GO:0050766 5 5 0,000 0,01660853 0,10482711 ! regulation of insulin receptor signaling pathway GO:0046626 5 5 0,000 0,01660853 0,10446934 ! antigen processing and presentation of exogenous antigen GO:0019884 5 5 0,000 0,01660853 0,104114 ! enucleate erythrocyte differentiation GO:0043353 6 5 0,000 0,01660853 0,10376107 ! response to amine stimulus GO:0014075 5 5 0,000 0,01660853 0,10341053 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 5 5 0,000 0,01660853 0,10306235 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 5 5 0,000 0,01660853 0,1027165 ! synaptic vesicle exocytosis GO:0016079 6 5 0,000 0,01660853 0,10237297 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 5 5 0,000 0,01660853 0,10203172 ! glycosylceramide metabolic process GO:0006677 5 5 0,000 0,01660853 0,10169275 ! neuron recognition GO:0008038 5 5 0,000 0,01660853 0,10135602 ! negative regulation of focal adhesion formation GO:0051895 6 5 0,000 0,01660853 0,10102151 ! decidualization GO:0046697 5 5 0,000 0,01660853 0,1006892 ! hair follicle maturation GO:0048820 5 5 0,000 0,01660853 0,10035907 ! phosphatidylinositol biosynthetic process GO:0006661 5 5 0,000 0,01660853 0,1000311 ! regulation of mitochondrial membrane potential GO:0051881 5 5 0,000 0,01660853 0,09970527 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 0,01660853 0,09938155 GO:0009155|purine deoxyribonucleotide catabolic process, ! regulation of interleukin-12 production GO:0032655 5 5 0,000 0,01660853 0,09905992 ! positive regulation of interleukin-6 production GO:0032755 5 5 0,000 0,01660853 0,09874038 ! positive regulation of monooxygenase activity GO:0032770 5 5 0,000 0,01660853 0,09842288 ! postreplication repair GO:0006301 5 5 0,000 0,01660853 0,09810742 ! spinal cord motor neuron differentiation GO:0021522 5 5 0,000 0,01660853 0,09779398 GO:0021517|ventral spinal cord development, ! cellular pigmentation GO:0033059 5 5 0,000 0,01660853 0,09748254 ! histone methylation GO:0016571 5 5 0,000 0,01660853 0,09717307 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,01660853 0,09686556 ! T cell lineage commitment GO:0002360 5 5 0,000 0,01660853 0,09655999 ! positive regulation of immunoglobulin mediated immune response GO:0002891 5 5 0,000 0,01660853 0,09625634 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of interferon-gamma production GO:0032729 5 5 0,000 0,01660853 0,0959546 ! negative regulation of tumor necrosis factor production GO:0032720 5 5 0,000 0,01660853 0,09565474 ! intracellular cholesterol transport GO:0032367 5 5 0,000 0,01660853 0,09535675 GO:0032366|intracellular sterol transport, ! regulation of mast cell activation GO:0033003 5 5 0,000 0,01660853 0,09506061 ! morphogenesis of a polarized epithelium GO:0001738 5 5 0,000 0,01660853 0,09476631 ! regulation of hormone metabolic process GO:0032350 5 5 0,000 0,01660853 0,09447382 ! regulation of transcription from RNA polymerase III promoter GO:0006359 5 5 0,000 0,01660853 0,09418313 ! regulation of inflammatory response to antigenic stimulus GO:0002861 5 5 0,000 0,01660853 0,09389422 ! sterol catabolic process GO:0016127 5 5 0,000 0,01660853 0,09360708 GO:0006707|cholesterol catabolic process, ! negative regulation of oxidoreductase activity GO:0051354 5 5 0,000 0,01660853 0,0933217 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 5 5 0,000 0,01660853 0,09303804 ! detection of biotic stimulus GO:0009595 5 5 0,000 0,01660853 0,09275611 ! regulation of immune response to tumor cell GO:0002837 5 5 0,000 0,01660853 0,09247588 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 5 5 0,000 0,01660853 0,09219734 ! zymogen activation GO:0031638 5 5 0,000 0,01660853 0,09192047 ! positive regulation of interleukin-1 beta secretion GO:0050718 5 5 0,000 0,01660853 0,09164526 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 5 5 0,000 0,01660853 0,09137169 GO:0002820|negative regulation of adaptive immune response, ! cellular response to nutrient GO:0031670 5 5 0,000 0,01660853 0,09109975 ! peptidyl-lysine modification GO:0018205 5 5 0,000 0,01660853 0,09082943 ! negative regulation of neuroblast proliferation GO:0007406 5 5 0,000 0,01660853 0,0905607 ! peptidyl-histidine modification GO:0018202 5 5 0,000 0,01660853 0,09029356 ! nucleosome positioning GO:0016584 5 5 0,000 0,01660853 0,09002799 ! regulation of isotype switching GO:0045191 5 5 0,000 0,01660853 0,08976398 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 5 5 0,000 0,01660853 0,08950151 ! negative regulation of neurological system process GO:0031645 5 5 0,000 0,01660853 0,08924057 ! regulation of myoblast differentiation GO:0045661 5 5 0,000 0,01660853 0,08898115 ! glutathione biosynthetic process GO:0006750 5 5 0,000 0,01660853 0,08872324 ! NADPH regeneration GO:0006740 5 5 0,000 0,01660853 0,08846681 GO:0006098|pentose-phosphate shunt, ! positive regulation of erythrocyte differentiation GO:0045648 5 5 0,000 0,01660853 0,08821186 ! positive regulation of epidermis development GO:0045684 5 5 0,000 0,01660853 0,08795838 ! positive regulation of leukocyte chemotaxis GO:0002690 5 5 0,000 0,01660853 0,08770635 GO:0002688|regulation of leukocyte chemotaxis, ! musculoskeletal movement GO:0050881 5 5 0,000 0,01660853 0,08745576 GO:0050879|multicellular organismal movement, ! neuromuscular process controlling posture GO:0050884 5 5 0,000 0,01660853 0,0872066 ! sarcomere organization GO:0045214 5 5 0,000 0,01660853 0,08695885 ! regulation of epidermal cell differentiation GO:0045604 5 5 0,000 0,01660853 0,08671251 ! activation of NF-kappaB-inducing kinase activity GO:0007250 5 5 0,000 0,01660853 0,08646756 ! negative regulation of glucose transport GO:0010829 5 5 0,000 0,01660853 0,08622399 GO:0046325|negative regulation of glucose import, ! positive regulation of T-helper cell differentiation GO:0045624 5 5 0,000 0,01660853 0,08598179 GO:0045622|regulation of T-helper cell differentiation, ! oocyte differentiation GO:0009994 5 5 0,000 0,01660853 0,08574094 GO:0048599|oocyte development, ! dopamine biosynthetic process GO:0042416 5 5 0,000 0,01660853 0,08550144 ! regulation of protein homodimerization activity GO:0043496 6 5 0,000 0,01660853 0,08526328 ! spleen development GO:0048536 5 5 0,000 0,01660853 0,08502643 ! male genitalia development GO:0030539 5 5 0,000 0,01660853 0,0847909 ! nicotinamide nucleotide biosynthetic process GO:0019359 5 5 0,000 0,01660853 0,08455668 ! quaternary ammonium group transport GO:0015697 5 5 0,000 0,01660853 0,08432374 ! thyroid hormone metabolic process GO:0042403 5 5 0,000 0,01660853 0,08409208 ! leukocyte mediated cytotoxicity GO:0001909 5 5 0,000 0,01660853 0,08386169 ! positive regulation of viral reproduction GO:0048524 5 5 0,000 0,01660853 0,08363256 ! removal of superoxide radicals GO:0019430 6 5 0,000 0,01660853 0,08340468 ! myeloid cell homeostasis GO:0002262 5 5 0,000 0,01660853 0,08317803 ! regulation of fatty acid oxidation GO:0046320 5 5 0,000 0,01660853 0,08295262 ! regulation of Rac protein signal transduction GO:0035020 5 5 0,000 0,01660853 0,08272842 ! ATP catabolic process GO:0006200 5 5 0,000 0,01660853 0,08250544 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,01660853 0,08228365 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 5 5 0,000 0,01660853 0,08206305 ! blastocyst formation GO:0001825 5 5 0,000 0,01660853 0,08184363 ! regulation of fibrinolysis GO:0051917 5 5 0,000 0,01660853 0,08162538 ! embryonic gut development GO:0048566 5 5 0,000 0,01660853 0,08140829 ! negative regulation of organic acid transport GO:0032891 5 5 0,000 0,01660853 0,08119235 ! pyrimidine base metabolic process GO:0006206 5 5 0,000 0,01660853 0,08097756 ! activation of innate immune response GO:0002218 5 5 0,000 0,01660853 0,0807639 GO:0002758|innate immune response-activating signal transduction, ! positive regulation of blood vessel endothelial cell migration GO:0043536 5 5 0,000 0,01660853 0,08055136 ! catecholamine transport GO:0051937 5 5 0,000 0,01660853 0,08033994 ! negative regulation of blood vessel endothelial cell migration GO:0043537 5 5 0,000 0,01660853 0,08012962 ! regulation of NF-kappaB import into nucleus GO:0042345 5 5 0,000 0,01660853 0,07992041 ! muscle adaptation GO:0043500 5 5 0,000 0,01660853 0,07971228 ! positive regulation of actin filament bundle formation GO:0032233 5 5 0,000 0,01660853 0,07950524 ! embryonic heart tube development GO:0035050 5 5 0,000 0,01660853 0,07929927 ! cardiac cell differentiation GO:0035051 6 5 0,000 0,01660853 0,07909436 ! positive regulation of homeostatic process GO:0032846 5 5 0,000 0,01660853 0,07889051 ! defense response to fungus GO:0050832 5 5 0,000 0,01660853 0,0786877 ! lysogeny GO:0030069 5 5 0,000 0,01660853 0,07848594 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 5 5 0,000 0,01660853 0,07828521 ! B cell receptor signaling pathway GO:0050853 5 5 0,000 0,01660853 0,0780855 ! positive regulation of smooth muscle contraction GO:0045987 5 5 0,000 0,01660853 0,07788681 ! response to nicotine GO:0035094 5 5 0,000 0,01660853 0,07768913 ! establishment of cell polarity GO:0030010 5 5 0,000 0,01660853 0,07749245 ! mitochondrion localization GO:0051646 5 5 0,000 0,01660853 0,07729676 ! nucleus localization GO:0051647 5 5 0,000 0,01660853 0,07710206 ! regulation of synapse structure and activity GO:0050803 5 5 0,000 0,01660853 0,07690833 ! potassium ion transport GO:0006813 60 60 1,000 0,01682308 0,07770663 ! positive regulation of cellular protein metabolic process GO:0032270 61 61 1,000 0,01735827 0,07997822 ! purine ribonucleoside triphosphate metabolic process GO:0009205 62 62 1,000 0,01790069 0,08227177 ! axonogenesis GO:0007409 66 62 1,000 0,01790069 0,08206711 ! regulation of cellular component biogenesis GO:0044087 63 62 1,000 0,01790069 0,08186347 ! protein import GO:0017038 62 62 1,000 0,01790069 0,08166084 ! regulation of lymphocyte activation GO:0051249 62 62 1,000 0,01790069 0,08145921 ! ribonucleoside triphosphate metabolic process GO:0009199 63 63 1,000 0,01845031 0,08375352 ! purine nucleoside triphosphate metabolic process GO:0009144 63 63 1,000 0,01845031 0,08354774 ! axon extension GO:0048675 7 6 0,000 0,01989842 0,08988428 ! oligosaccharide biosynthetic process GO:0009312 6 6 0,000 0,01989842 0,08966451 ! N-terminal protein amino acid modification GO:0031365 6 6 0,000 0,01989842 0,08944582 GO:0018409|peptide or protein amino-terminal blocking, ! tRNA modification GO:0006400 6 6 0,000 0,01989842 0,08922819 ! somatic diversification of immune receptors via somatic mutation GO:0002566 6 6 0,000 0,01989842 0,08901162 GO:0016446|somatic hypermutation of immunoglobulin genes, ! 'de novo' posttranslational protein folding GO:0051084 6 6 0,000 0,01989842 0,08879609 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 6 6 0,000 0,01989842 0,08858161 ! negative regulation of cellular catabolic process GO:0031330 6 6 0,000 0,01989842 0,08836816 ! virus-host interaction GO:0019048 6 6 0,000 0,01989842 0,08815574 ! regulation of S phase GO:0033261 6 6 0,000 0,01989842 0,08794433 ! myotube differentiation GO:0014902 6 6 0,000 0,01989842 0,08773394 ! regulation of B cell proliferation GO:0030888 6 6 0,000 0,01989842 0,08752455 ! bone remodeling GO:0046849 6 6 0,000 0,01989842 0,08731616 ! N-glycan processing GO:0006491 6 6 0,000 0,01989842 0,08710876 ! regulation of lipid kinase activity GO:0043550 6 6 0,000 0,01989842 0,08690234 ! glycosaminoglycan catabolic process GO:0006027 6 6 0,000 0,01989842 0,08669689 ! negative regulation of JAK-STAT cascade GO:0046426 6 6 0,000 0,01989842 0,08649242 ! retina development in camera-type eye GO:0060041 6 6 0,000 0,01989842 0,08628891 ! RNA methylation GO:0001510 6 6 0,000 0,01989842 0,08608635 ! cartilage condensation GO:0001502 7 6 0,000 0,01989842 0,08588475 ! regulation of activated T cell proliferation GO:0046006 6 6 0,000 0,01989842 0,08568408 ! regulation of positive chemotaxis GO:0050926 6 6 0,000 0,01989842 0,08548435 GO:0050927|positive regulation of positive chemotaxis, ! artery development GO:0060840 6 6 0,000 0,01989842 0,08528555 GO:0048844|artery morphogenesis, ! positive regulation of neurotransmitter transport GO:0051590 6 6 0,000 0,01989842 0,08508767 ! bile acid metabolic process GO:0008206 6 6 0,000 0,01989842 0,08489071 ! androgen metabolic process GO:0008209 6 6 0,000 0,01989842 0,08469466 ! estrogen metabolic process GO:0008210 6 6 0,000 0,01989842 0,08449951 ! limbic system development GO:0021761 7 6 0,000 0,01989842 0,08430526 ! cytoplasmic sequestering of transcription factor GO:0042994 6 6 0,000 0,01989842 0,0841119 ! positive regulation of transcription factor import into nucleus GO:0042993 6 6 0,000 0,01989842 0,08391942 ! positive regulation of heart contraction GO:0045823 6 6 0,000 0,01989842 0,08372782 ! positive regulation of gene expression, epigenetic GO:0045815 6 6 0,000 0,01989842 0,0835371 ! negative regulation of protein amino acid phosphorylation GO:0001933 6 6 0,000 0,01989842 0,08334724 ! positive regulation of cell growth GO:0030307 6 6 0,000 0,01989842 0,08315825 ! ribonucleoside triphosphate catabolic process GO:0009203 6 6 0,000 0,01989842 0,08297011 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! regulation of chemokine biosynthetic process GO:0045073 6 6 0,000 0,01989842 0,08278281 ! nerve growth factor receptor signaling pathway GO:0048011 6 6 0,000 0,01989842 0,08259637 ! inositol phosphate-mediated signaling GO:0048016 6 6 0,000 0,01989842 0,08241076 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 6 6 0,000 0,01989842 0,08222598 ! arginine metabolic process GO:0006525 6 6 0,000 0,01989842 0,08204203 GO:0006527|arginine catabolic process, ! regulation of catecholamine secretion GO:0050433 6 6 0,000 0,01989842 0,0818589 ! oligodendrocyte differentiation GO:0048709 6 6 0,000 0,01989842 0,08167658 ! glutamate catabolic process GO:0006538 7 6 0,000 0,01989842 0,08149508 ! telomere maintenance via telomerase GO:0007004 6 6 0,000 0,01989842 0,08131438 GO:0010833|telomere maintenance via telomere lengthening, ! L-phenylalanine metabolic process GO:0006558 6 6 0,000 0,01989842 0,08113448 GO:0006559|L-phenylalanine catabolic process, ! glucan biosynthetic process GO:0009250 6 6 0,000 0,01989842 0,08095538 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 6 6 0,000 0,01989842 0,08077706 ! ER overload response GO:0006983 6 6 0,000 0,01989842 0,08059953 ! V(D)J recombination GO:0033151 6 6 0,000 0,01989842 0,08042278 ! focal adhesion formation GO:0048041 7 6 0,000 0,01989842 0,0802468 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 0,01989842 0,08007159 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 6 6 0,000 0,01989842 0,07989714 ! negative regulation of endothelial cell migration GO:0010596 6 6 0,000 0,01989842 0,07972345 ! regulation of heart rate GO:0002027 6 6 0,000 0,01989842 0,07955051 ! lipid digestion GO:0044241 6 6 0,000 0,01989842 0,07937833 ! asymmetric protein localization GO:0008105 6 6 0,000 0,01989842 0,07920688 ! retrograde transport, endosome to Golgi GO:0042147 6 6 0,000 0,01989842 0,07903618 ! phagocytosis, engulfment GO:0006911 6 6 0,000 0,01989842 0,07886621 ! Rac protein signal transduction GO:0016601 6 6 0,000 0,01989842 0,07869697 ! regulation of vascular permeability GO:0043114 6 6 0,000 0,01989842 0,07852845 ! regulation of calcium ion transport into cytosol GO:0010522 6 6 0,000 0,01989842 0,07836065 ! ruffle organization GO:0031529 6 6 0,000 0,01989842 0,07819357 ! peptidyl-serine phosphorylation GO:0018105 6 6 0,000 0,01989842 0,07802721 ! preassembly of GPI anchor in ER membrane GO:0016254 6 6 0,000 0,01989842 0,07786154 ! retinoic acid metabolic process GO:0042573 6 6 0,000 0,01989842 0,07769658 ! neutral amino acid transport GO:0015804 6 6 0,000 0,01989842 0,07753232 ! L-amino acid transport GO:0015807 6 6 0,000 0,01989842 0,07736875 ! bone mineralization GO:0030282 6 6 0,000 0,01989842 0,07720587 GO:0031214|biomineral formation, ! rRNA modification GO:0000154 6 6 0,000 0,01989842 0,07704367 ! negative regulation of ossification GO:0030279 6 6 0,000 0,01989842 0,07688215 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 6 6 0,000 0,01989842 0,07672131 GO:0002717|positive regulation of natural killer cell mediated immunity, GO:0002715|regulation of natural killer cell mediated immunity, GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of bone resorption GO:0045124 6 6 0,000 0,01989842 0,07656114 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 7 6 0,000 0,01989842 0,07640164 ! purine base biosynthetic process GO:0009113 6 6 0,000 0,01989842 0,0762428 ! G1 DNA damage checkpoint GO:0031571 6 6 0,000 0,01989842 0,07608462 ! negative regulation of axonogenesis GO:0050771 7 6 0,000 0,01989842 0,07592709 ! regulation of phagocytosis GO:0050764 6 6 0,000 0,01989842 0,07577022 ! regulation of organ growth GO:0046620 6 6 0,000 0,01989842 0,07561399 ! regulation of circadian rhythm GO:0042752 6 6 0,000 0,01989842 0,07545841 ! positive regulation of T cell mediated immunity GO:0002711 6 6 0,000 0,01989842 0,07530346 ! response to dsRNA GO:0043331 6 6 0,000 0,01989842 0,07514915 ! DNA unwinding during replication GO:0006268 6 6 0,000 0,01989842 0,07499547 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 6 6 0,000 0,01989842 0,07484242 GO:0009147|pyrimidine nucleoside triphosphate metabolic process, ! genitalia development GO:0048806 6 6 0,000 0,01989842 0,07468999 ! sphingomyelin metabolic process GO:0006684 6 6 0,000 0,01989842 0,07453818 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 6 6 0,000 0,01989842 0,07438699 ! positive regulation of B cell differentiation GO:0045579 6 6 0,000 0,01989842 0,07423641 ! multicellular organismal aging GO:0010259 6 6 0,000 0,01989842 0,07408644 ! regulation of focal adhesion formation GO:0051893 7 6 0,000 0,01989842 0,07393707 ! respiratory chain complex IV assembly GO:0008535 6 6 0,000 0,01989842 0,0737883 ! erythrocyte development GO:0048821 6 6 0,000 0,01989842 0,07364013 ! renal water homeostasis GO:0003091 6 6 0,000 0,01989842 0,07349256 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 6 6 0,000 0,01989842 0,07334557 GO:0043372|positive regulation of CD4-positive, alpha beta T cell differentiation, ! ribosomal large subunit biogenesis GO:0042273 6 6 0,000 0,01989842 0,07319917 ! regulation of Rho GTPase activity GO:0032319 6 6 0,000 0,01989842 0,07305336 ! ribosome assembly GO:0042255 6 6 0,000 0,01989842 0,07290812 ! positive regulation of Ras GTPase activity GO:0032320 6 6 0,000 0,01989842 0,07276347 ! diencephalon development GO:0021536 6 6 0,000 0,01989842 0,07261938 ! fucose catabolic process GO:0019317 6 6 0,000 0,01989842 0,07247586 GO:0042355|L-fucose catabolic process, ! nitric oxide metabolic process GO:0046209 6 6 0,000 0,01989842 0,07233291 GO:0006809|nitric oxide biosynthetic process, ! protein sumoylation GO:0016925 6 6 0,000 0,01989842 0,07219052 ! regulation of lipid transport GO:0032368 6 6 0,000 0,01989842 0,0720487 ! regulation of cell division GO:0051302 6 6 0,000 0,01989842 0,07190742 ! positive regulation of interleukin-1 secretion GO:0050716 6 6 0,000 0,01989842 0,07176671 ! cellular metabolic compound salvage GO:0043094 6 6 0,000 0,01989842 0,07162654 ! regulation of T-helper 2 type immune response GO:0002828 6 6 0,000 0,01989842 0,07148691 ! salivary gland morphogenesis GO:0007435 6 6 0,000 0,01989842 0,07134783 ! neuroblast proliferation GO:0007405 6 6 0,000 0,01989842 0,07120929 ! regulation of interleukin-1 beta secretion GO:0050706 6 6 0,000 0,01989842 0,07107129 ! nitric oxide mediated signal transduction GO:0007263 6 6 0,000 0,01989842 0,07093382 ! regulation of glucose transport GO:0010827 6 6 0,000 0,01989842 0,07079689 GO:0046324|regulation of glucose import, ! intestinal absorption GO:0050892 6 6 0,000 0,01989842 0,07066048 ! methionine biosynthetic process GO:0009086 6 6 0,000 0,01989842 0,07052459 ! glutamine family amino acid biosynthetic process GO:0009084 6 6 0,000 0,01989842 0,07038923 ! serine family amino acid biosynthetic process GO:0009070 6 6 0,000 0,01989842 0,07025438 ! thymus development GO:0048538 6 6 0,000 0,01989842 0,07012005 ! lymph node development GO:0048535 6 6 0,000 0,01989842 0,06998623 ! organic cation transport GO:0015695 6 6 0,000 0,01989842 0,06985293 ! negative regulation of BMP signaling pathway GO:0030514 6 6 0,000 0,01989842 0,06972013 ! regulation of RNA splicing GO:0043484 6 6 0,000 0,01989842 0,06958783 ! regulation of cellular carbohydrate catabolic process GO:0043471 6 6 0,000 0,01989842 0,06945604 GO:0043470|regulation of carbohydrate catabolic process, GO:0006110|regulation of glycolysis, ! positive regulation of JNK cascade GO:0046330 7 6 0,000 0,01989842 0,06932474 ! sperm-egg recognition GO:0035036 7 6 0,000 0,01989842 0,06919394 GO:0007339|binding of sperm to zona pellucida, ! germ cell migration GO:0008354 6 6 0,000 0,01989842 0,06906363 ! establishment or maintenance of apical/basal cell polarity GO:0035088 6 6 0,000 0,01989842 0,06893381 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 6 6 0,000 0,01989842 0,06880448 ! alditol metabolic process GO:0019400 6 6 0,000 0,01989842 0,06867563 ! regulation of synaptic transmission, GABAergic GO:0032228 6 6 0,000 0,01989842 0,06854726 ! regulation of amino acid transport GO:0051955 6 6 0,000 0,01989842 0,06841938 ! maternal placenta development GO:0001893 6 6 0,000 0,01989842 0,06829197 ! regulation of embryonic development GO:0045995 6 6 0,000 0,01989842 0,06816503 ! negative regulation of immune effector process GO:0002698 6 6 0,000 0,01989842 0,06803856 ! nucleoside triphosphate metabolic process GO:0009141 66 66 1,000 0,02014185 0,06874337 ! cell morphogenesis involved in neuron differentiation GO:0048667 72 67 1,000 0,02071975 0,07058502 GO:0048812|neuron projection morphogenesis, GO:0048858|cell projection morphogenesis, ! striated muscle tissue development GO:0014706 69 67 1,000 0,02071975 0,07045479 ! response to radiation GO:0009314 70 68 1,000 0,0213046 0,07231008 ! purine ribonucleotide biosynthetic process GO:0009152 68 68 1,000 0,0213046 0,07217716 ! regulation of leukocyte activation GO:0002694 69 69 1,000 0,02189635 0,07404581 ! cell part morphogenesis GO:0032990 75 70 1,000 0,02249495 0,07593075 ! wound healing GO:0042060 74 70 1,000 0,02249495 0,07579194 ! muscle tissue development GO:0060537 72 70 1,000 0,02249495 0,07565363 ! regulation of cell migration GO:0030334 71 71 1,000 0,02310035 0,07754817 ! regulation of cell activation GO:0050865 71 71 1,000 0,02310035 0,07740718 ! respiratory burst GO:0045730 7 7 0,000 0,02317778 0,07752568 ! negative regulation of cell projection organization GO:0031345 8 7 0,000 0,02317778 0,07738524 ! positive regulation of blood pressure GO:0045777 7 7 0,000 0,02317778 0,0772453 ! positive regulation of cellular catabolic process GO:0031331 7 7 0,000 0,02317778 0,07710587 ! pteridine and derivative biosynthetic process GO:0042559 7 7 0,000 0,02317778 0,07696694 ! regulation of chemokine production GO:0032642 7 7 0,000 0,02317778 0,07682851 ! double-strand break repair via homologous recombination GO:0000724 7 7 0,000 0,02317778 0,07669058 GO:0000725|recombinational repair, ! positive regulation of GTPase activity GO:0043547 7 7 0,000 0,02317778 0,07655314 ! SMAD protein nuclear translocation GO:0007184 7 7 0,000 0,02317778 0,07641619 ! cellular protein complex disassembly GO:0043624 8 7 0,000 0,02317778 0,07627973 GO:0043241|protein complex disassembly, ! hair follicle morphogenesis GO:0031069 7 7 0,000 0,02317778 0,07614376 ! gene silencing by RNA GO:0031047 7 7 0,000 0,02317778 0,07600828 ! regulation of receptor-mediated endocytosis GO:0048259 7 7 0,000 0,02317778 0,07587327 ! regulation of neurotransmitter transport GO:0051588 7 7 0,000 0,02317778 0,07573874 ! keratinocyte proliferation GO:0043616 7 7 0,000 0,02317778 0,07560469 ! axis specification GO:0009798 7 7 0,000 0,02317778 0,07547112 ! negative regulation of muscle cell differentiation GO:0051148 7 7 0,000 0,02317778 0,07533801 ! visual behavior GO:0007632 7 7 0,000 0,02317778 0,07520537 GO:0008542|visual learning, ! startle response GO:0001964 7 7 0,000 0,02317778 0,0750732 ! amyloid precursor protein metabolic process GO:0042982 7 7 0,000 0,02317778 0,07494149 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 8 7 0,000 0,02317778 0,07481025 ! positive regulation of lipid metabolic process GO:0045834 7 7 0,000 0,02317778 0,07467946 ! negative regulation of lipid metabolic process GO:0045833 7 7 0,000 0,02317778 0,07454913 ! regulation of interferon-gamma biosynthetic process GO:0045072 7 7 0,000 0,02317778 0,07441925 ! endothelial cell differentiation GO:0045446 7 7 0,000 0,02317778 0,07428983 ! negative regulation of striated muscle development GO:0045843 7 7 0,000 0,02317778 0,07416085 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 7 7 0,000 0,02317778 0,07403232 ! digestive system development GO:0055123 7 7 0,000 0,02317778 0,07390424 GO:0048546|digestive tract morphogenesis, GO:0048547|gut morphogenesis, ! hemoglobin metabolic process GO:0020027 7 7 0,000 0,02317778 0,0737766 ! regulation of exit from mitosis GO:0007096 7 7 0,000 0,02317778 0,0736494 ! protein targeting to ER GO:0045047 8 7 0,000 0,02317778 0,07352264 ! cell differentiation in spinal cord GO:0021515 7 7 0,000 0,02317778 0,07339631 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 7 7 0,000 0,02317778 0,07327041 ! endoderm development GO:0007492 7 7 0,000 0,02317778 0,07314495 ! regulation of defense response to virus GO:0050688 7 7 0,000 0,02317778 0,07301992 ! glycolipid biosynthetic process GO:0009247 7 7 0,000 0,02317778 0,07289531 GO:0006688|glycosphingolipid biosynthetic process, ! response to hexose stimulus GO:0009746 7 7 0,000 0,02317778 0,07277113 GO:0034284|response to monosaccharide stimulus, GO:0009749|response to glucose stimulus, ! membrane protein ectodomain proteolysis GO:0006509 7 7 0,000 0,02317778 0,07264737 GO:0033619|membrane protein proteolysis, ! positive regulation of survival gene product expression GO:0045885 7 7 0,000 0,02317778 0,07252403 ! regulation of skeletal muscle fiber development GO:0048742 7 7 0,000 0,02317778 0,0724011 ! cardiac muscle tissue development GO:0048738 7 7 0,000 0,02317778 0,0722786 ! nucleotide-sugar metabolic process GO:0009225 7 7 0,000 0,02317778 0,07215651 ! complement activation, alternative pathway GO:0006957 7 7 0,000 0,02317778 0,07203482 ! arachidonic acid secretion GO:0050482 7 7 0,000 0,02317778 0,07191355 GO:0032309|icosanoid secretion, ! polyamine biosynthetic process GO:0006596 7 7 0,000 0,02317778 0,07179269 ! response to X-ray GO:0010165 7 7 0,000 0,02317778 0,07167223 ! regulation of intracellular pH GO:0051453 7 7 0,000 0,02317778 0,07155218 ! UV protection GO:0009650 7 7 0,000 0,02317778 0,07143253 ! DNA integration GO:0015074 7 7 0,000 0,02317778 0,07131327 ! myofibril assembly GO:0030239 7 7 0,000 0,02317778 0,07119442 GO:0055002|striated muscle cell development, ! positive regulation of carbohydrate metabolic process GO:0045913 7 7 0,000 0,02317778 0,07107596 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! positive regulation of muscle contraction GO:0045933 7 7 0,000 0,02317778 0,07095789 ! negative regulation of muscle contraction GO:0045932 7 7 0,000 0,02317778 0,07084022 ! chondroitin sulfate biosynthetic process GO:0030206 7 7 0,000 0,02317778 0,07072293 GO:0030204|chondroitin sulfate metabolic process, ! regulation of exocytosis GO:0017157 8 7 0,000 0,02317778 0,07060604 ! phosphatidylcholine biosynthetic process GO:0006656 7 7 0,000 0,02317778 0,07048952 ! heparan sulfate proteoglycan metabolic process GO:0030201 7 7 0,000 0,02317778 0,0703734 GO:0015012|heparan sulfate proteoglycan biosynthetic process, ! stem cell development GO:0048864 7 7 0,000 0,02317778 0,07025765 GO:0019827|stem cell maintenance, ! alpha-beta T cell differentiation GO:0046632 7 7 0,000 0,02317778 0,07014228 ! negative regulation of myeloid leukocyte differentiation GO:0002762 7 7 0,000 0,02317778 0,0700273 ! NLS-bearing substrate import into nucleus GO:0006607 7 7 0,000 0,02317778 0,06991269 ! axon cargo transport GO:0008088 7 7 0,000 0,02317778 0,06979845 ! eating behavior GO:0042755 7 7 0,000 0,02317778 0,06968459 ! RNA-dependent DNA replication GO:0006278 7 7 0,000 0,02317778 0,06957109 ! purine nucleoside triphosphate catabolic process GO:0009146 7 7 0,000 0,02317778 0,06945797 ! regulation of interleukin-8 production GO:0032677 7 7 0,000 0,02317778 0,06934521 ! purine ribonucleotide catabolic process GO:0009154 7 7 0,000 0,02317778 0,06923282 ! ribosomal small subunit biogenesis GO:0042274 7 7 0,000 0,02317778 0,06912079 ! cranial nerve development GO:0021545 7 7 0,000 0,02317778 0,06900913 ! protein import into peroxisome matrix GO:0016558 7 7 0,000 0,02317778 0,06889782 ! induction of an organ GO:0001759 7 7 0,000 0,02317778 0,06878688 ! leukocyte activation during immune response GO:0002366 7 7 0,000 0,02317778 0,06867629 GO:0002263|cell activation during immune response, ! response to estradiol stimulus GO:0032355 7 7 0,000 0,02317778 0,06856605 ! autonomic nervous system development GO:0048483 7 7 0,000 0,02317778 0,06845617 ! intracellular lipid transport GO:0032365 7 7 0,000 0,02317778 0,06834664 ! detection of chemical stimulus GO:0009593 8 7 0,000 0,02317778 0,06823746 ! platelet activation GO:0030168 8 7 0,000 0,02317778 0,06812863 ! negative regulation of cytokine secretion GO:0050710 7 7 0,000 0,02317778 0,06802015 ! regulation of interleukin-1 secretion GO:0050704 7 7 0,000 0,02317778 0,06791201 ! natural killer cell activation GO:0030101 7 7 0,000 0,02317778 0,06780421 ! response to gamma radiation GO:0010332 8 7 0,000 0,02317778 0,06769675 ! NADP metabolic process GO:0006739 7 7 0,000 0,02317778 0,06758964 ! neuromuscular synaptic transmission GO:0007274 7 7 0,000 0,02317778 0,06748286 ! synaptic transmission, cholinergic GO:0007271 7 7 0,000 0,02317778 0,06737642 ! ubiquinone metabolic process GO:0006743 7 7 0,000 0,02317778 0,06727032 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, GO:0042375|quinone cofactor metabolic process, ! regulation of macrophage differentiation GO:0045649 8 7 0,000 0,02317778 0,06716455 ! positive regulation of acute inflammatory response GO:0002675 7 7 0,000 0,02317778 0,06705911 ! regulation of osteoclast differentiation GO:0045670 7 7 0,000 0,02317778 0,066954 ! negative regulation of cell-substrate adhesion GO:0010812 8 7 0,000 0,02317778 0,06684922 GO:0001953|negative regulation of cell-matrix adhesion, ! multicellular organismal water homeostasis GO:0050891 7 7 0,000 0,02317778 0,06674477 ! regulation of ATPase activity GO:0043462 7 7 0,000 0,02317778 0,06664064 ! cell-cell recognition GO:0009988 8 7 0,000 0,02317778 0,06653684 ! hormone catabolic process GO:0042447 7 7 0,000 0,02317778 0,06643336 ! dopamine metabolic process GO:0042417 7 7 0,000 0,02317778 0,0663302 ! cAMP biosynthetic process GO:0006171 7 7 0,000 0,02317778 0,06622737 ! oxygen transport GO:0015671 7 7 0,000 0,02317778 0,06612485 ! pyridine nucleotide biosynthetic process GO:0019363 7 7 0,000 0,02317778 0,06602264 ! regulation of mRNA stability GO:0043488 7 7 0,000 0,02317778 0,06592076 ! biogenic amine catabolic process GO:0042402 7 7 0,000 0,02317778 0,06581919 ! regulation of axon extension GO:0030516 7 7 0,000 0,02317778 0,06571792 ! cell killing GO:0001906 7 7 0,000 0,02317778 0,06561698 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 7 7 0,000 0,02317778 0,06551634 ! adult feeding behavior GO:0008343 7 7 0,000 0,02317778 0,065416 ! pyrimidine nucleotide catabolic process GO:0006244 7 7 0,000 0,02317778 0,06531598 ! positive regulation of protein polymerization GO:0032273 7 7 0,000 0,02317778 0,06521626 ! T cell receptor signaling pathway GO:0050852 7 7 0,000 0,02317778 0,06511685 ! response to cold GO:0009409 7 7 0,000 0,02317778 0,06501773 ! positive regulation of hydrolase activity GO:0051345 72 72 1,000 0,02371251 0,06641665 ! ribonucleotide biosynthetic process GO:0009260 75 75 1,000 0,02558904 0,07156387 ! response to oxidative stress GO:0006979 76 75 1,000 0,02558904 0,07145544 ! purine ribonucleotide metabolic process GO:0009150 75 75 1,000 0,02558904 0,07134734 ! positive regulation of multicellular organismal process GO:0051240 76 76 1,000 0,02622774 0,0730177 ! regulation of skeletal muscle tissue development GO:0048641 8 8 0,000 0,02644665 0,07351609 ! negative regulation of muscle development GO:0048635 8 8 0,000 0,02644665 0,07340538 ! very-long-chain fatty acid metabolic process GO:0000038 8 8 0,000 0,02644665 0,07329499 ! positive regulation of translation GO:0045727 8 8 0,000 0,02644665 0,07318494 ! positive regulation of cell killing GO:0031343 8 8 0,000 0,02644665 0,07307522 ! superoxide anion generation GO:0042554 8 8 0,000 0,02644665 0,07296582 ! sulfur amino acid biosynthetic process GO:0000097 8 8 0,000 0,02644665 0,07285676 ! cGMP metabolic process GO:0046068 8 8 0,000 0,02644665 0,07274801 GO:0006182|cGMP biosynthetic process, ! thyroid gland development GO:0030878 8 8 0,000 0,02644665 0,0726396 ! 'de novo' protein folding GO:0006458 8 8 0,000 0,02644665 0,0725315 ! dicarboxylic acid transport GO:0006835 8 8 0,000 0,02644665 0,07242373 ! phosphoinositide phosphorylation GO:0046854 8 8 0,000 0,02644665 0,07231628 ! negative regulation of bone remodeling GO:0046851 8 8 0,000 0,02644665 0,07220914 ! embryonic hindlimb morphogenesis GO:0035116 8 8 0,000 0,02644665 0,07210232 ! embryonic forelimb morphogenesis GO:0035115 8 8 0,000 0,02644665 0,07199582 ! folic acid and derivative biosynthetic process GO:0009396 8 8 0,000 0,02644665 0,07188963 ! regulation of neuronal synaptic plasticity GO:0048168 8 8 0,000 0,02644665 0,07178376 ! cardiac muscle contraction GO:0060048 8 8 0,000 0,02644665 0,07167819 ! lipid localization GO:0010876 8 8 0,000 0,02644665 0,07157294 GO:0019915|lipid storage, ! response to pain GO:0048265 8 8 0,000 0,02644665 0,07146799 ! response to cAMP GO:0051591 8 8 0,000 0,02644665 0,07136335 ! COPI coating of Golgi vesicle GO:0048205 8 8 0,000 0,02644665 0,07125902 GO:0048200|Golgi transport vesicle coating, ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 8 0,000 0,02644665 0,07115499 ! negative regulation of transcription factor import into nucleus GO:0042992 8 8 0,000 0,02644665 0,07105127 ! negative regulation of ion transport GO:0043271 8 8 0,000 0,02644665 0,07094785 ! regulation of response to extracellular stimulus GO:0032104 8 8 0,000 0,02644665 0,07084472 GO:0032107|regulation of response to nutrient levels, ! adult walking behavior GO:0007628 8 8 0,000 0,02644665 0,0707419 ! sensory perception of taste GO:0050909 8 8 0,000 0,02644665 0,07063938 ! organelle fusion GO:0048284 8 8 0,000 0,02644665 0,07053715 ! pancreas development GO:0031016 8 8 0,000 0,02644665 0,07043522 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 8 8 0,000 0,02644665 0,07033358 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! T cell selection GO:0045058 8 8 0,000 0,02644665 0,07023223 ! negative regulation of proteolysis GO:0045861 8 8 0,000 0,02644665 0,07013118 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 8 8 0,000 0,02644665 0,07003042 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 8 8 0,000 0,02644665 0,06992994 ! sperm motility GO:0030317 8 8 0,000 0,02644665 0,06982976 ! regulation of striated muscle contraction GO:0006942 8 8 0,000 0,02644665 0,06972986 ! DNA duplex unwinding GO:0032508 8 8 0,000 0,02644665 0,06963024 GO:0032392|DNA geometric change, ! glycine metabolic process GO:0006544 8 8 0,000 0,02644665 0,06953091 ! ribonucleotide catabolic process GO:0009261 8 8 0,000 0,02644665 0,06943187 ! negative regulation of microtubule depolymerization GO:0007026 8 8 0,000 0,02644665 0,0693331 GO:0031114|regulation of microtubule depolymerization, ! polyamine metabolic process GO:0006595 8 8 0,000 0,02644665 0,06923462 ! Golgi organization GO:0007030 8 8 0,000 0,02644665 0,06913641 ! cell-cell junction assembly GO:0007043 8 8 0,000 0,02644665 0,06903848 ! regulation of stress fiber formation GO:0051492 9 8 0,000 0,02644665 0,06894083 ! positive regulation of endothelial cell migration GO:0010595 8 8 0,000 0,02644665 0,06884346 ! fructose metabolic process GO:0006000 8 8 0,000 0,02644665 0,06874636 ! mannose metabolic process GO:0006013 9 8 0,000 0,02644665 0,06864954 ! NAD metabolic process GO:0019674 8 8 0,000 0,02644665 0,06855298 ! sex determination GO:0007530 8 8 0,000 0,02644665 0,0684567 ! negative regulation of mitotic cell cycle GO:0045930 9 8 0,000 0,02644665 0,06836069 ! plasma membrane fusion GO:0045026 8 8 0,000 0,02644665 0,06826494 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 8 8 0,000 0,02644665 0,06816947 ! response to fungus GO:0009620 8 8 0,000 0,02644665 0,06807426 ! stem cell differentiation GO:0048863 8 8 0,000 0,02644665 0,06797932 ! alpha-beta T cell activation GO:0046631 8 8 0,000 0,02644665 0,06788464 ! positive regulation of myeloid leukocyte differentiation GO:0002763 9 8 0,000 0,02644665 0,06779022 ! embryonic digit morphogenesis GO:0042733 8 8 0,000 0,02644665 0,06769607 ! regulation of cytokine production during immune response GO:0002718 8 8 0,000 0,02644665 0,06760218 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 0,02644665 0,06750855 ! regulation of vasodilation GO:0042312 8 8 0,000 0,02644665 0,06741517 ! vasoconstriction GO:0042310 8 8 0,000 0,02644665 0,06732206 ! regulation of T cell mediated immunity GO:0002709 8 8 0,000 0,02644665 0,0672292 ! muscle cell development GO:0055001 8 8 0,000 0,02644665 0,0671366 ! nucleoside triphosphate catabolic process GO:0009143 8 8 0,000 0,02644665 0,06704425 ! regulation of fatty acid metabolic process GO:0019217 8 8 0,000 0,02644665 0,06695216 ! sensory perception of pain GO:0019233 8 8 0,000 0,02644665 0,06686032 ! gastrulation with mouth forming second GO:0001702 8 8 0,000 0,02644665 0,06676873 ! immunoglobulin production during immune response GO:0002381 8 8 0,000 0,02644665 0,06667739 GO:0002208|somatic diversification of immunoglobulins during immune response, GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! mRNA cleavage GO:0006379 8 8 0,000 0,02644665 0,0665863 ! chromatin silencing GO:0006342 8 8 0,000 0,02644665 0,06649546 ! tissue regeneration GO:0042246 8 8 0,000 0,02644665 0,06640486 ! salivary gland development GO:0007431 8 8 0,000 0,02644665 0,06631452 ! negative regulation of blood coagulation GO:0030195 9 8 0,000 0,02644665 0,06622442 ! T cell homeostasis GO:0043029 8 8 0,000 0,02644665 0,06613456 ! peptide biosynthetic process GO:0043043 9 8 0,000 0,02644665 0,06604495 ! peptidyl-serine modification GO:0018209 8 8 0,000 0,02644665 0,06595557 ! water homeostasis GO:0030104 8 8 0,000 0,02644665 0,06586645 ! cofactor transport GO:0051181 8 8 0,000 0,02644665 0,06577756 ! regulation of acute inflammatory response GO:0002673 8 8 0,000 0,02644665 0,06568891 ! acid secretion GO:0046717 8 8 0,000 0,02644665 0,0656005 ! positive regulation of leukocyte migration GO:0002687 8 8 0,000 0,02644665 0,06551233 ! C21-steroid hormone biosynthetic process GO:0006700 8 8 0,000 0,02644665 0,06542439 ! protein-chromophore linkage GO:0018298 9 8 0,000 0,02644665 0,06533669 ! regulation of immunoglobulin production GO:0002637 8 8 0,000 0,02644665 0,06524922 ! catecholamine biosynthetic process GO:0042423 8 8 0,000 0,02644665 0,06516199 ! regulation of RNA stability GO:0043487 8 8 0,000 0,02644665 0,06507499 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 8 8 0,000 0,02644665 0,06498823 ! regulation of generation of precursor metabolites and energy GO:0043467 8 8 0,000 0,02644665 0,06490169 ! aromatic compound biosynthetic process GO:0019438 8 8 0,000 0,02644665 0,06481539 ! release of cytochrome c from mitochondria GO:0001836 9 8 0,000 0,02644665 0,06472931 ! regulation of organic acid transport GO:0032890 8 8 0,000 0,02644665 0,06464346 ! positive regulation of calcium ion transport GO:0051928 8 8 0,000 0,02644665 0,06455784 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 8 8 0,000 0,02644665 0,06447245 ! regulation of multi-organism process GO:0043900 8 8 0,000 0,02644665 0,06438728 ! positive regulation of amine transport GO:0051954 8 8 0,000 0,02644665 0,06430233 ! developmental induction GO:0031128 8 8 0,000 0,02644665 0,06421762 GO:0045168|cell-cell signaling involved in cell fate specification, ! peptide hormone secretion GO:0030072 8 8 0,000 0,02644665 0,06413312 ! positive regulation of calcium-mediated signaling GO:0050850 8 8 0,000 0,02644665 0,06404884 ! actin filament polymerization GO:0030041 9 8 0,000 0,02644665 0,06396479 ! cytoplasmic sequestering of protein GO:0051220 8 8 0,000 0,02644665 0,06388096 ! peptide hormone processing GO:0016486 8 8 0,000 0,02644665 0,06379734 ! positive regulation of synaptic transmission GO:0050806 8 8 0,000 0,02644665 0,06371395 ! regulation of steroid biosynthetic process GO:0050810 8 8 0,000 0,02644665 0,06363077 ! cell morphogenesis involved in differentiation GO:0000904 82 77 1,000 0,02687296 0,06457218 ! positive regulation of protein kinase cascade GO:0010740 79 78 1,000 0,02752465 0,06605199 ! regulation of locomotion GO:0040012 79 79 1,000 0,02818277 0,06754336 ! nuclear transport GO:0051169 79 79 1,000 0,02818277 0,06745564 GO:0006913|nucleocytoplasmic transport, ! regulation of cell motion GO:0051270 79 79 1,000 0,02818277 0,06736815 ! neuron projection development GO:0031175 85 80 1,000 0,02884726 0,06886724 ! lactation GO:0007595 10 9 0,000 0,02970505 0,07082329 ! embryonic pattern specification GO:0009880 10 9 0,000 0,02970505 0,07073179 ! positive regulation of cell size GO:0045793 9 9 0,000 0,02970505 0,07064052 ! positive regulation of cell projection organization GO:0031346 9 9 0,000 0,02970505 0,07054949 ! regulation of membrane protein ectodomain proteolysis GO:0051043 9 9 0,000 0,02970505 0,07045869 ! positive regulation of protein complex assembly GO:0031334 9 9 0,000 0,02970505 0,07036813 ! cortical actin cytoskeleton organization GO:0030866 10 9 0,000 0,02970505 0,07027779 ! negative regulation of cell cycle process GO:0010948 9 9 0,000 0,02970505 0,07018769 ! viral genome replication GO:0019079 9 9 0,000 0,02970505 0,07009783 ! phospholipid catabolic process GO:0009395 9 9 0,000 0,02970505 0,07000819 ! copper ion transport GO:0006825 9 9 0,000 0,02970505 0,06991878 ! lipid phosphorylation GO:0046834 9 9 0,000 0,02970505 0,06982959 ! aminoglycan catabolic process GO:0006026 9 9 0,000 0,02970505 0,06974064 ! Golgi vesicle budding GO:0048194 9 9 0,000 0,02970505 0,06965191 ! regulation of cell-cell adhesion GO:0022407 9 9 0,000 0,02970505 0,06956341 ! RNA polyadenylation GO:0043631 9 9 0,000 0,02970505 0,06947513 GO:0006378|mRNA polyadenylation, ! gamma-aminobutyric acid signaling pathway GO:0007214 9 9 0,000 0,02970505 0,06938707 ! regulation of postsynaptic membrane potential GO:0060078 9 9 0,000 0,02970505 0,06929924 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 9 9 0,000 0,02970505 0,06921163 ! negative regulation of cytokine biosynthetic process GO:0042036 9 9 0,000 0,02970505 0,06912424 ! phospholipid efflux GO:0033700 9 9 0,000 0,02970505 0,06903708 ! response to alkaloid GO:0043279 10 9 0,000 0,02970505 0,06895013 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 9 9 0,000 0,02970505 0,0688634 ! cytokine biosynthetic process GO:0042089 9 9 0,000 0,02970505 0,06877689 GO:0042107|cytokine metabolic process, ! positive regulation of endothelial cell proliferation GO:0001938 9 9 0,000 0,02970505 0,06869059 ! negative regulation of gene expression, epigenetic GO:0045814 9 9 0,000 0,02970505 0,06860451 ! regulation of interleukin-2 biosynthetic process GO:0045076 9 9 0,000 0,02970505 0,06851865 ! response to ethanol GO:0045471 9 9 0,000 0,02970505 0,068433 ! platelet-derived growth factor receptor signaling pathway GO:0048008 9 9 0,000 0,02970505 0,06834757 ! pyrimidine ribonucleotide metabolic process GO:0009218 9 9 0,000 0,02970505 0,06826235 ! activation of pro-apoptotic gene products GO:0008633 9 9 0,000 0,02970505 0,06817734 ! methionine metabolic process GO:0006555 9 9 0,000 0,02970505 0,06809254 ! glutamine metabolic process GO:0006541 9 9 0,000 0,02970505 0,06800795 ! cerebral cortex development GO:0021987 9 9 0,000 0,02970505 0,06792358 ! response to osmotic stress GO:0006970 9 9 0,000 0,02970505 0,06783941 ! pigmentation during development GO:0048066 9 9 0,000 0,02970505 0,06775545 ! reverse cholesterol transport GO:0043691 9 9 0,000 0,02970505 0,0676717 ! central nervous system neuron development GO:0021954 10 9 0,000 0,02970505 0,06758815 ! pyrimidine ribonucleoside metabolic process GO:0046131 9 9 0,000 0,02970505 0,06750481 ! nucleobase biosynthetic process GO:0046112 9 9 0,000 0,02970505 0,06742168 ! substrate-bound cell migration GO:0006929 9 9 0,000 0,02970505 0,06733875 ! neurotransmitter metabolic process GO:0042133 11 9 0,000 0,02970505 0,06725602 ! negative regulation of caspase activity GO:0043154 9 9 0,000 0,02970505 0,0671735 ! branching involved in ureteric bud morphogenesis GO:0001658 9 9 0,000 0,02970505 0,06709118 GO:0060675|ureteric bud morphogenesis, ! L-glutamate transport GO:0015813 9 9 0,000 0,02970505 0,06700906 GO:0015800|acidic amino acid transport, ! peptide secretion GO:0002790 9 9 0,000 0,02970505 0,06692714 ! regulation of dephosphorylation GO:0035303 9 9 0,000 0,02970505 0,06684542 ! cotranslational protein targeting to membrane GO:0006613 10 9 0,000 0,02970505 0,0667639 ! positive regulation of alpha-beta T cell differentiation GO:0046638 9 9 0,000 0,02970505 0,06668258 ! ventricular cardiac muscle morphogenesis GO:0055010 9 9 0,000 0,02970505 0,06660146 ! behavioral interaction between organisms GO:0051705 9 9 0,000 0,02970505 0,06652054 ! negative regulation of protein import into nucleus GO:0042308 9 9 0,000 0,02970505 0,06643981 ! positive regulation of protein import into nucleus GO:0042307 9 9 0,000 0,02970505 0,06635927 ! DNA replication initiation GO:0006270 9 9 0,000 0,02970505 0,06627894 ! prostaglandin metabolic process GO:0006693 9 9 0,000 0,02970505 0,06619879 GO:0006692|prostanoid metabolic process, ! T cell differentiation in the thymus GO:0033077 9 9 0,000 0,02970505 0,06611884 ! regulation of cellular pH GO:0030641 9 9 0,000 0,02970505 0,06603909 ! histone acetylation GO:0016573 9 9 0,000 0,02970505 0,06595952 ! DNA fragmentation involved in apoptosis GO:0006309 9 9 0,000 0,02970505 0,06588015 ! regulation of immunoglobulin mediated immune response GO:0002889 9 9 0,000 0,02970505 0,06580096 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 10 9 0,000 0,02970505 0,06572197 ! positive regulation of oxidoreductase activity GO:0051353 9 9 0,000 0,02970505 0,06564317 ! positive regulation of cytokine secretion GO:0050715 9 9 0,000 0,02970505 0,06556455 ! negative regulation of inflammatory response GO:0050728 9 9 0,000 0,02970505 0,06548613 ! negative regulation of tissue remodeling GO:0034104 9 9 0,000 0,02970505 0,06540789 ! negative regulation of protein secretion GO:0050709 9 9 0,000 0,02970505 0,06532984 ! regulation of leukocyte migration GO:0002685 9 9 0,000 0,02970505 0,06525197 ! positive regulation of transmission of nerve impulse GO:0051971 9 9 0,000 0,02970505 0,06517429 ! aromatic amino acid family catabolic process GO:0009074 9 9 0,000 0,02970505 0,06509679 ! purine base metabolic process GO:0006144 9 9 0,000 0,02970505 0,06501948 ! gas transport GO:0015669 9 9 0,000 0,02970505 0,06494235 ! cholesterol efflux GO:0033344 9 9 0,000 0,02970505 0,0648654 ! regulation of leukocyte mediated cytotoxicity GO:0001910 9 9 0,000 0,02970505 0,06478864 ! estrogen receptor signaling pathway GO:0030520 9 9 0,000 0,02970505 0,06471206 ! somatic recombination of immunoglobulin gene segments GO:0016447 9 9 0,000 0,02970505 0,06463566 ! regulation of actin filament bundle formation GO:0032231 10 9 0,000 0,02970505 0,06455944 ! regulation of blood vessel endothelial cell migration GO:0043535 9 9 0,000 0,02970505 0,06448339 ! defense response to virus GO:0051607 9 9 0,000 0,02970505 0,06440753 ! regulation of calcium-mediated signaling GO:0050848 9 9 0,000 0,02970505 0,06433185 ! actin filament-based movement GO:0030048 9 9 0,000 0,02970505 0,06425634 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 9 9 0,000 0,02970505 0,06418101 ! ribonucleotide metabolic process GO:0009259 83 83 1,000 0,03087857 0,06663842 ! cellular amino acid derivative metabolic process GO:0006575 87 84 1,000 0,03156813 0,06804686 ! regulation of cellular localization GO:0060341 86 85 1,000 0,03226384 0,06946525 ! protein import into nucleus, docking GO:0000059 10 10 0,000 0,03295301 0,07086628 ! regulation of protein ubiquitination GO:0031396 10 10 0,000 0,03295301 0,07078369 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 10 10 0,000 0,03295301 0,07070129 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 10 10 0,000 0,03295301 0,07061908 ! regulation of glucose metabolic process GO:0010906 10 10 0,000 0,03295301 0,07053706 ! ER-associated protein catabolic process GO:0030433 10 10 0,000 0,03295301 0,07045523 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of cell killing GO:0031341 10 10 0,000 0,03295301 0,07037359 ! neuron maturation GO:0042551 10 10 0,000 0,03295301 0,07029214 ! pteridine and derivative metabolic process GO:0042558 10 10 0,000 0,03295301 0,07021087 ! positive regulation of anti-apoptosis GO:0045768 10 10 0,000 0,03295301 0,0701298 GO:0045767|regulation of anti-apoptosis, ! cortical cytoskeleton organization GO:0030865 11 10 0,000 0,03295301 0,07004891 ! regulation of lipid biosynthetic process GO:0046890 10 10 0,000 0,03295301 0,06996821 ! reciprocal meiotic recombination GO:0007131 10 10 0,000 0,03295301 0,06988769 ! hormone secretion GO:0046879 10 10 0,000 0,03295301 0,06980736 ! glucosamine metabolic process GO:0006041 10 10 0,000 0,03295301 0,06972722 GO:0006044|N-acetylglucosamine metabolic process, ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 10 10 0,000 0,03295301 0,06964725 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! inositol metabolic process GO:0006020 10 10 0,000 0,03295301 0,06956747 ! cAMP metabolic process GO:0046058 10 10 0,000 0,03295301 0,06948788 ! vesicle targeting, to, from or within Golgi GO:0048199 10 10 0,000 0,03295301 0,06940846 ! transcription from RNA polymerase III promoter GO:0006383 10 10 0,000 0,03295301 0,06932923 ! forelimb morphogenesis GO:0035136 10 10 0,000 0,03295301 0,06925018 ! glial cell development GO:0021782 10 10 0,000 0,03295301 0,0691713 ! phototransduction GO:0007602 11 10 0,000 0,03295301 0,06909261 ! calcium-independent cell-cell adhesion GO:0016338 10 10 0,000 0,03295301 0,0690141 ! auditory receptor cell differentiation GO:0042491 10 10 0,000 0,03295301 0,06893576 ! apoptotic mitochondrial changes GO:0008637 11 10 0,000 0,03295301 0,0688576 ! fat cell differentiation GO:0045444 10 10 0,000 0,03295301 0,06877962 ! myoblast differentiation GO:0045445 10 10 0,000 0,03295301 0,06870182 ! centrosome cycle GO:0007098 10 10 0,000 0,03295301 0,06862419 ! inactivation of MAPK activity GO:0000188 10 10 0,000 0,03295301 0,06854673 ! positive regulation of proteolysis GO:0045862 10 10 0,000 0,03295301 0,06846945 ! response to carbohydrate stimulus GO:0009743 10 10 0,000 0,03295301 0,06839235 ! regulation of survival gene product expression GO:0045884 10 10 0,000 0,03295301 0,06831542 ! induction of apoptosis via death domain receptors GO:0008625 10 10 0,000 0,03295301 0,06823866 ! epidermis morphogenesis GO:0048730 10 10 0,000 0,03295301 0,06816207 ! protein polyubiquitination GO:0000209 10 10 0,000 0,03295301 0,06808566 ! glutamate metabolic process GO:0006536 11 10 0,000 0,03295301 0,06800941 ! plasma membrane organization GO:0007009 10 10 0,000 0,03295301 0,06793334 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 10 10 0,000 0,03295301 0,06785744 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cell-substrate junction assembly GO:0007044 11 10 0,000 0,03295301 0,0677817 ! lysosomal transport GO:0007041 10 10 0,000 0,03295301 0,06770614 ! cellular response to unfolded protein GO:0034620 10 10 0,000 0,03295301 0,06763074 GO:0030968|endoplasmic reticulum unfolded protein response, ! central nervous system neuron differentiation GO:0021953 11 10 0,000 0,03295301 0,06755551 ! purine ribonucleoside metabolic process GO:0046128 10 10 0,000 0,03295301 0,06748045 GO:0042278|purine nucleoside metabolic process, ! vesicle coating GO:0006901 10 10 0,000 0,03295301 0,06740556 ! exocrine system development GO:0035272 10 10 0,000 0,03295301 0,06733083 ! cell structure disassembly during apoptosis GO:0006921 10 10 0,000 0,03295301 0,06725626 ! embryo implantation GO:0007566 11 10 0,000 0,03295301 0,06718186 ! regulation of protein binding GO:0043393 11 10 0,000 0,03295301 0,06710763 ! protein targeting to peroxisome GO:0006625 10 10 0,000 0,03295301 0,06703356 ! protein targeting to mitochondrion GO:0006626 10 10 0,000 0,03295301 0,06695965 GO:0070585|protein localization in mitochondrion, ! regulation of alpha-beta T cell differentiation GO:0046637 10 10 0,000 0,03295301 0,06688591 ! intermediate filament cytoskeleton organization GO:0045104 10 10 0,000 0,03295301 0,06681233 ! protein export from nucleus GO:0006611 10 10 0,000 0,03295301 0,06673891 ! negative regulation of immune response GO:0050777 10 10 0,000 0,03295301 0,06666565 ! cytolysis GO:0019835 10 10 0,000 0,03295301 0,06659255 ! positive regulation of biomineral formation GO:0070169 10 10 0,000 0,03295301 0,06651961 GO:0030501|positive regulation of bone mineralization, ! mismatch repair GO:0006298 10 10 0,000 0,03295301 0,06644683 ! regulation of B cell differentiation GO:0045577 10 10 0,000 0,03295301 0,06637421 ! mRNA splice site selection GO:0006376 11 10 0,000 0,03295301 0,06630175 ! synaptic vesicle transport GO:0048489 11 10 0,000 0,03295301 0,06622945 ! gland morphogenesis GO:0022612 10 10 0,000 0,03295301 0,0661573 ! positive regulation of neurological system process GO:0031646 10 10 0,000 0,03295301 0,06608532 ! sphingolipid biosynthetic process GO:0030148 10 10 0,000 0,03295301 0,06601348 GO:0046467|membrane lipid biosynthetic process, ! sphingolipid catabolic process GO:0030149 10 10 0,000 0,03295301 0,06594181 GO:0046466|membrane lipid catabolic process, ! nerve-nerve synaptic transmission GO:0007270 10 10 0,000 0,03295301 0,06587029 ! regulation of erythrocyte differentiation GO:0045646 10 10 0,000 0,03295301 0,06579892 ! regulation of epidermis development GO:0045682 10 10 0,000 0,03295301 0,06572771 ! folic acid and derivative metabolic process GO:0006760 10 10 0,000 0,03295301 0,06565665 ! negative regulation of neuron differentiation GO:0045665 10 10 0,000 0,03295301 0,06558575 ! aspartate family amino acid biosynthetic process GO:0009067 10 10 0,000 0,03295301 0,065515 ! regulation of BMP signaling pathway GO:0030510 10 10 0,000 0,03295301 0,0654444 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 10 10 0,000 0,03295301 0,06537396 ! lymphocyte homeostasis GO:0002260 10 10 0,000 0,03295301 0,06530366 ! nerve development GO:0021675 10 10 0,000 0,03295301 0,06523352 ! epithelial to mesenchymal transition GO:0001837 10 10 0,000 0,03295301 0,06516353 ! gut development GO:0048565 10 10 0,000 0,03295301 0,06509368 ! embryonic organ morphogenesis GO:0048562 10 10 0,000 0,03295301 0,06502399 ! positive regulation of neuron apoptosis GO:0043525 10 10 0,000 0,03295301 0,06495444 ! negative regulation of homeostatic process GO:0032845 10 10 0,000 0,03295301 0,06488505 ! mRNA 3'-end processing GO:0031124 10 10 0,000 0,03295301 0,0648158 ! antigen receptor-mediated signaling pathway GO:0050851 10 10 0,000 0,03295301 0,0647467 ! negative regulation of coagulation GO:0050819 11 10 0,000 0,03295301 0,06467775 ! protein stabilization GO:0050821 10 10 0,000 0,03295301 0,06460894 ! regulation of anatomical structure morphogenesis GO:0022603 90 86 1,000 0,03296565 0,06456503 ! heart development GO:0007507 90 87 1,000 0,03367353 0,06588143 ! purine nucleotide biosynthetic process GO:0006164 88 88 1,000 0,03438742 0,0672068 ! brain development GO:0007420 91 90 1,000 0,03583308 0,06995802 ! protein secretion GO:0009306 11 11 0,000 0,03619058 0,07058121 ! oligosaccharide metabolic process GO:0009311 11 11 0,000 0,03619058 0,0705066 ! myeloid leukocyte differentiation GO:0002573 12 11 0,000 0,03619058 0,07043214 ! negative regulation of defense response GO:0031348 11 11 0,000 0,03619058 0,07035785 ! G1 phase of mitotic cell cycle GO:0000080 12 11 0,000 0,03619058 0,07028371 ! determination of bilateral symmetry GO:0009855 11 11 0,000 0,03619058 0,07020973 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! positive regulation of hormone secretion GO:0046887 11 11 0,000 0,03619058 0,0701359 ! phosphatidylinositol metabolic process GO:0046488 11 11 0,000 0,03619058 0,07006223 ! skin development GO:0043588 11 11 0,000 0,03619058 0,06998871 ! cellular component assembly involved in morphogenesis GO:0010927 11 11 0,000 0,03619058 0,06991535 ! signal complex assembly GO:0007172 11 11 0,000 0,03619058 0,06984214 ! microtubule-based transport GO:0010970 11 11 0,000 0,03619058 0,06976908 ! endothelial cell migration GO:0043542 11 11 0,000 0,03619058 0,06969618 ! peroxisomal transport GO:0043574 11 11 0,000 0,03619058 0,06962342 ! protein amino acid methylation GO:0006479 11 11 0,000 0,03619058 0,06955082 GO:0008213|protein amino acid alkylation, ! protein amino acid acetylation GO:0006473 11 11 0,000 0,03619058 0,06947838 ! positive regulation of nucleocytoplasmic transport GO:0046824 11 11 0,000 0,03619058 0,06940608 GO:0032388|positive regulation of intracellular transport, ! heart contraction GO:0060047 11 11 0,000 0,03619058 0,06933393 GO:0003015|heart process, ! detection of light stimulus involved in sensory perception GO:0050962 12 11 0,000 0,03619058 0,06926193 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 11 11 0,000 0,03619058 0,06919008 ! T cell proliferation GO:0042098 11 11 0,000 0,03619058 0,06911838 ! regulation of transmembrane transporter activity GO:0022898 11 11 0,000 0,03619058 0,06904683 GO:0032412|regulation of ion transmembrane transporter activity, GO:0032409|regulation of transporter activity, ! negative regulation of endothelial cell proliferation GO:0001937 11 11 0,000 0,03619058 0,06897543 ! regulation of viral genome replication GO:0045069 11 11 0,000 0,03619058 0,06890417 ! spinal cord development GO:0021510 11 11 0,000 0,03619058 0,06883307 ! smooth muscle contraction GO:0006939 11 11 0,000 0,03619058 0,0687621 ! cellular response to starvation GO:0009267 11 11 0,000 0,03619058 0,06869129 ! cellular macromolecular complex disassembly GO:0034623 12 11 0,000 0,03619058 0,06862062 ! digestive system process GO:0022600 11 11 0,000 0,03619058 0,06855009 ! mitotic spindle organization GO:0007052 11 11 0,000 0,03619058 0,06847971 ! fucose metabolic process GO:0006004 11 11 0,000 0,03619058 0,06840948 ! membrane budding GO:0006900 11 11 0,000 0,03619058 0,06833939 ! apoptotic nuclear changes GO:0030262 11 11 0,000 0,03619058 0,06826944 ! monoamine transport GO:0015844 11 11 0,000 0,03619058 0,06819963 ! regulation of cellular ketone metabolic process GO:0010565 11 11 0,000 0,03619058 0,06812997 ! response to lipopolysaccharide GO:0032496 11 11 0,000 0,03619058 0,06806045 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 11 11 0,000 0,03619058 0,06799107 ! body fluid secretion GO:0007589 11 11 0,000 0,03619058 0,06792183 ! G1/S transition checkpoint GO:0031575 12 11 0,000 0,03619058 0,06785274 ! positive regulation of alpha-beta T cell activation GO:0046635 11 11 0,000 0,03619058 0,06778378 ! intermediate filament-based process GO:0045103 11 11 0,000 0,03619058 0,06771496 ! cardiac muscle tissue morphogenesis GO:0055008 11 11 0,000 0,03619058 0,06764629 GO:0060415|muscle tissue morphogenesis, ! interaction with host GO:0051701 11 11 0,000 0,03619058 0,06757775 ! membrane depolarization GO:0051899 11 11 0,000 0,03619058 0,06750935 ! regulation of interleukin-2 production GO:0032663 11 11 0,000 0,03619058 0,06744109 ! regulation of ARF GTPase activity GO:0032312 11 11 0,000 0,03619058 0,06737297 ! oogenesis GO:0048477 11 11 0,000 0,03619058 0,06730499 ! negative regulation of angiogenesis GO:0016525 11 11 0,000 0,03619058 0,06723714 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 11 11 0,000 0,03619058 0,06716943 ! regulation of cellular carbohydrate metabolic process GO:0010675 11 11 0,000 0,03619058 0,06710185 GO:0006109|regulation of carbohydrate metabolic process, ! vitamin transport GO:0051180 11 11 0,000 0,03619058 0,06703441 ! muscle maintenance GO:0046716 12 11 0,000 0,03619058 0,06696711 ! vitamin A metabolic process GO:0006776 11 11 0,000 0,03619058 0,06689994 ! hindbrain development GO:0030902 11 11 0,000 0,03619058 0,06683291 ! steroid catabolic process GO:0006706 11 11 0,000 0,03619058 0,06676601 ! endocrine process GO:0050886 11 11 0,000 0,03619058 0,06669924 GO:0001990|regulation of systemic arterial blood pressure by hormone, ! aromatic amino acid family metabolic process GO:0009072 11 11 0,000 0,03619058 0,06663261 ! proximal/distal pattern formation GO:0009954 11 11 0,000 0,03619058 0,06656611 ! somatic diversification of immunoglobulins GO:0016445 11 11 0,000 0,03619058 0,06649974 ! RNA 3'-end processing GO:0031123 11 11 0,000 0,03619058 0,06643351 ! negative regulation of cell cycle GO:0045786 92 91 1,000 0,03656476 0,06705359 ! fatty acid metabolic process GO:0006631 93 92 1,000 0,03730228 0,06833808 ! translational initiation GO:0006413 12 12 0,000 0,03941778 0,07214197 ! positive regulation of angiogenesis GO:0045766 12 12 0,000 0,03941778 0,0720704 ! initiation of viral infection GO:0019059 12 12 0,000 0,03941778 0,07199897 ! DNA catabolic process, endonucleolytic GO:0000737 12 12 0,000 0,03941778 0,07192769 ! iron ion transport GO:0006826 13 12 0,000 0,03941778 0,07185654 ! phosphatidylcholine metabolic process GO:0046470 12 12 0,000 0,03941778 0,07178554 ! amino sugar metabolic process GO:0006040 12 12 0,000 0,03941778 0,07171467 ! post-Golgi vesicle-mediated transport GO:0006892 12 12 0,000 0,03941778 0,07164395 ! protein amino acid ADP-ribosylation GO:0006471 12 12 0,000 0,03941778 0,07157336 ! heterophilic cell adhesion GO:0007157 12 12 0,000 0,03941778 0,07150292 ! hindlimb morphogenesis GO:0035137 12 12 0,000 0,03941778 0,07143261 ! xenobiotic metabolic process GO:0006805 12 12 0,000 0,03941778 0,07136244 ! glutamate signaling pathway GO:0007215 12 12 0,000 0,03941778 0,07129241 ! C21-steroid hormone metabolic process GO:0008207 13 12 0,000 0,03941778 0,07122251 ! regulation of muscle cell differentiation GO:0051147 13 12 0,000 0,03941778 0,07115276 ! cellular response to hydrogen peroxide GO:0070301 12 12 0,000 0,03941778 0,07108314 GO:0042744|hydrogen peroxide catabolic process, ! negative regulation of peptidase activity GO:0010466 12 12 0,000 0,03941778 0,07101365 ! actomyosin structure organization GO:0031032 12 12 0,000 0,03941778 0,0709443 ! microtubule organizing center organization GO:0031023 12 12 0,000 0,03941778 0,07087509 GO:0051297|centrosome organization, ! positive regulation of endocytosis GO:0045807 12 12 0,000 0,03941778 0,07080601 ! retinoid metabolic process GO:0001523 12 12 0,000 0,03941778 0,07073706 GO:0016101|diterpenoid metabolic process, ! mitotic chromosome condensation GO:0007076 12 12 0,000 0,03941778 0,07066825 ! positive regulation of innate immune response GO:0045089 12 12 0,000 0,03941778 0,07059958 ! GPI anchor biosynthetic process GO:0006506 12 12 0,000 0,03941778 0,07053103 GO:0006505|GPI anchor metabolic process, ! glycoprotein catabolic process GO:0006516 13 12 0,000 0,03941778 0,07046262 ! acute-phase response GO:0006953 12 12 0,000 0,03941778 0,07039435 ! deoxyribonucleotide catabolic process GO:0009264 12 12 0,000 0,03941778 0,0703262 ! vacuolar transport GO:0007034 12 12 0,000 0,03941778 0,07025819 ! polysaccharide catabolic process GO:0000272 12 12 0,000 0,03941778 0,0701903 ! vesicle docking during exocytosis GO:0006904 12 12 0,000 0,03941778 0,07012255 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 12 12 0,000 0,03941778 0,07005493 ! barbed-end actin filament capping GO:0051016 12 12 0,000 0,03941778 0,06998744 GO:0051693|actin filament capping, ! osteoblast differentiation GO:0001649 12 12 0,000 0,03941778 0,06992008 ! male gonad development GO:0008584 12 12 0,000 0,03941778 0,06985285 ! regulation of insulin secretion GO:0050796 12 12 0,000 0,03941778 0,06978575 ! regulation of alpha-beta T cell activation GO:0046634 12 12 0,000 0,03941778 0,06971878 ! renal system process GO:0003014 12 12 0,000 0,03941778 0,06965193 ! regulation of tumor necrosis factor production GO:0032680 12 12 0,000 0,03941778 0,06958522 ! regulation of steroid metabolic process GO:0019218 12 12 0,000 0,03941778 0,06951863 ! fibroblast growth factor receptor signaling pathway GO:0008543 12 12 0,000 0,03941778 0,06945216 ! regulation of interleukin-6 production GO:0032675 12 12 0,000 0,03941778 0,06938583 ! pallium development GO:0021543 13 12 0,000 0,03941778 0,06931962 ! cell fate determination GO:0001709 12 12 0,000 0,03941778 0,06925354 ! regulation of chromosome organization GO:0033044 12 12 0,000 0,03941778 0,06918759 ! somitogenesis GO:0001756 13 12 0,000 0,03941778 0,06912176 ! G1 phase GO:0051318 13 12 0,000 0,03941778 0,06905605 ! regulation of response to biotic stimulus GO:0002831 12 12 0,000 0,03941778 0,06899047 ! positive regulation of adaptive immune response GO:0002821 12 12 0,000 0,03941778 0,06892501 ! detection of light stimulus GO:0009583 13 12 0,000 0,03941778 0,06885968 ! synaptogenesis GO:0007416 12 12 0,000 0,03941778 0,06879447 ! fat-soluble vitamin metabolic process GO:0006775 12 12 0,000 0,03941778 0,06872939 ! hormone transport GO:0009914 12 12 0,000 0,03941778 0,06866443 ! neurotransmitter secretion GO:0007269 14 12 0,000 0,03941778 0,06859959 ! heme biosynthetic process GO:0006783 12 12 0,000 0,03941778 0,06853487 ! spermatid differentiation GO:0048515 13 12 0,000 0,03941778 0,06847028 GO:0007286|spermatid development, ! aromatic compound catabolic process GO:0019439 13 12 0,000 0,03941778 0,0684058 ! pyrimidine nucleotide biosynthetic process GO:0006221 12 12 0,000 0,03941778 0,06834145 ! neural tube closure GO:0001843 13 12 0,000 0,03941778 0,06827722 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! regulation of mitotic metaphase/anaphase transition GO:0030071 13 12 0,000 0,03941778 0,06821311 ! negative regulation of translation GO:0017148 12 12 0,000 0,03941778 0,06814912 ! regulation of microtubule polymerization or depolymerization GO:0031110 12 12 0,000 0,03941778 0,06808525 ! cellular monovalent inorganic cation homeostasis GO:0030004 12 12 0,000 0,03941778 0,0680215 ! endocytosis GO:0006897 99 98 1,000 0,04184766 0,0721471 GO:0010324|membrane invagination, ! positive regulation of DNA replication GO:0045740 14 13 0,000 0,04263464 0,07343517 ! positive regulation of smooth muscle cell proliferation GO:0048661 13 13 0,000 0,04263464 0,07336661 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 13 13 0,000 0,04263464 0,07329817 GO:0016444|somatic cell DNA recombination, ! negative regulation of actin filament polymerization GO:0030837 13 13 0,000 0,04263464 0,07322986 ! phenol metabolic process GO:0018958 13 13 0,000 0,04263464 0,07316167 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, GO:0009712|catechol metabolic process, ! G2/M transition of mitotic cell cycle GO:0000086 13 13 0,000 0,04263464 0,07309362 ! gluconeogenesis GO:0006094 13 13 0,000 0,04263464 0,07302568 ! negative regulation of hormone secretion GO:0046888 13 13 0,000 0,04263464 0,07295788 ! 2'-deoxyribonucleotide metabolic process GO:0009394 13 13 0,000 0,04263464 0,0728902 GO:0019692|deoxyribose phosphate metabolic process, ! intra-Golgi vesicle-mediated transport GO:0006891 13 13 0,000 0,04263464 0,07282265 ! glycosaminoglycan biosynthetic process GO:0006024 13 13 0,000 0,04263464 0,07275522 ! regeneration GO:0031099 13 13 0,000 0,04263464 0,07268792 ! keratinization GO:0031424 13 13 0,000 0,04263464 0,07262074 ! post-embryonic development GO:0009791 14 13 0,000 0,04263464 0,07255368 ! negative regulation of protein modification process GO:0031400 13 13 0,000 0,04263464 0,07248675 ! patterning of blood vessels GO:0001569 13 13 0,000 0,04263464 0,07241994 ! vasculogenesis GO:0001570 13 13 0,000 0,04263464 0,07235326 ! regulation of DNA recombination GO:0000018 13 13 0,000 0,04263464 0,07228669 ! regulation of innate immune response GO:0045088 13 13 0,000 0,04263464 0,07222025 ! mitochondrial membrane organization GO:0007006 13 13 0,000 0,04263464 0,07215394 ! negative regulation of DNA replication GO:0008156 13 13 0,000 0,04263464 0,07208774 ! response to corticosteroid stimulus GO:0031960 13 13 0,000 0,04263464 0,07202167 GO:0051384|response to glucocorticoid stimulus, ! autophagy GO:0006914 13 13 0,000 0,04263464 0,07195571 ! receptor metabolic process GO:0043112 14 13 0,000 0,04263464 0,07188988 ! actin filament bundle formation GO:0051017 13 13 0,000 0,04263464 0,07182417 ! negative regulation of protein catabolic process GO:0042177 13 13 0,000 0,04263464 0,07175857 ! ureteric bud development GO:0001657 13 13 0,000 0,04263464 0,0716931 ! cell aging GO:0007569 13 13 0,000 0,04263464 0,07162775 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 13 13 0,000 0,04263464 0,07156251 ! regulation of endothelial cell migration GO:0010594 13 13 0,000 0,04263464 0,07149739 ! response to endoplasmic reticulum stress GO:0034976 13 13 0,000 0,04263464 0,0714324 ! coenzyme catabolic process GO:0009109 13 13 0,000 0,04263464 0,07136752 GO:0046356|acetyl-CoA catabolic process, GO:0006099|tricarboxylic acid cycle, ! negative regulation of protein kinase cascade GO:0010741 13 13 0,000 0,04263464 0,07130276 ! purine nucleoside monophosphate metabolic process GO:0009126 13 13 0,000 0,04263464 0,07123811 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of peptide secretion GO:0002791 13 13 0,000 0,04263464 0,07117358 ! regulation of viral reproduction GO:0050792 13 13 0,000 0,04263464 0,07110917 ! nucleobase metabolic process GO:0009112 13 13 0,000 0,04263464 0,07104488 ! regulation of axonogenesis GO:0050770 14 13 0,000 0,04263464 0,0709807 ! positive regulation of neurogenesis GO:0050769 13 13 0,000 0,04263464 0,07091664 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 14 13 0,000 0,04263464 0,07085269 ! nucleotide-excision repair, DNA gap filling GO:0006297 13 13 0,000 0,04263464 0,07078886 ! vasodilation GO:0042311 14 13 0,000 0,04263464 0,07072515 ! positive regulation of leukocyte mediated immunity GO:0002705 13 13 0,000 0,04263464 0,07066154 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 13 13 0,000 0,04263464 0,07059806 ! glycosphingolipid metabolic process GO:0006687 13 13 0,000 0,04263464 0,07053468 GO:0006664|glycolipid metabolic process, ! positive regulation of locomotion GO:0040017 13 13 0,000 0,04263464 0,07047142 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, GO:0050920|regulation of chemotaxis, ! neural crest cell migration GO:0001755 14 13 0,000 0,04263464 0,07040828 ! neutrophil chemotaxis GO:0030593 14 13 0,000 0,04263464 0,07034524 ! long-chain fatty acid transport GO:0015909 13 13 0,000 0,04263464 0,07028232 ! immunoglobulin production GO:0002377 13 13 0,000 0,04263464 0,07021951 GO:0002440|production of molecular mediator of immune response, ! negative regulation of Wnt receptor signaling pathway GO:0030178 13 13 0,000 0,04263464 0,07015682 ! cell-cell junction organization GO:0045216 13 13 0,000 0,04263464 0,07009423 ! regulation of cell-substrate adhesion GO:0010810 14 13 0,000 0,04263464 0,07003176 GO:0001952|regulation of cell-matrix adhesion, ! negative regulation of myeloid cell differentiation GO:0045638 13 13 0,000 0,04263464 0,0699694 ! response to cytokine stimulus GO:0034097 13 13 0,000 0,04263464 0,06990715 ! activation of JUN kinase activity GO:0007257 13 13 0,000 0,04263464 0,06984501 ! terpenoid metabolic process GO:0006721 13 13 0,000 0,04263464 0,06978298 ! alkene biosynthetic process GO:0043450 13 13 0,000 0,04263464 0,06972106 GO:0019370|leukotriene biosynthetic process, ! purine nucleotide catabolic process GO:0006195 13 13 0,000 0,04263464 0,06965925 ! porphyrin biosynthetic process GO:0006779 13 13 0,000 0,04263464 0,06959755 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of cytokine production GO:0001818 13 13 0,000 0,04263464 0,06953596 ! camera-type eye morphogenesis GO:0048593 13 13 0,000 0,04263464 0,06947448 ! pyrimidine nucleoside metabolic process GO:0006213 13 13 0,000 0,04263464 0,06941311 ! blastocyst development GO:0001824 13 13 0,000 0,04263464 0,06935184 ! telomere organization GO:0032200 13 13 0,000 0,04263464 0,06929068 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 13 13 0,000 0,04263464 0,06922964 ! regulation of amine transport GO:0051952 13 13 0,000 0,04263464 0,06916869 ! inner ear receptor cell differentiation GO:0060113 13 13 0,000 0,04263464 0,06910786 ! protein tetramerization GO:0051262 13 13 0,000 0,04263464 0,06904713 ! response to hormone stimulus GO:0009725 102 100 1,000 0,04340757 0,07023719 ! muscle organ development GO:0007517 102 100 1,000 0,04340757 0,07017558 ! negative regulation of transcription from RNA polymerase II promoter GO:0000122 103 100 1,000 0,04340757 0,07011407 ! neuron fate commitment GO:0048663 14 14 0,000 0,04584119 0,07398014 ! sulfur amino acid metabolic process GO:0000096 14 14 0,000 0,04584119 0,07391541 ! regulation of interferon-gamma production GO:0032649 14 14 0,000 0,04584119 0,0738508 ! pyruvate metabolic process GO:0006090 14 14 0,000 0,04584119 0,0737863 ! cellular aldehyde metabolic process GO:0006081 14 14 0,000 0,04584119 0,07372192 ! acetyl-CoA metabolic process GO:0006084 14 14 0,000 0,04584119 0,07365764 ! cellular iron ion homeostasis GO:0006879 14 14 0,000 0,04584119 0,07359348 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 14 14 0,000 0,04584119 0,07352943 ! protein amino acid acylation GO:0043543 14 14 0,000 0,04584119 0,07346549 ! regulation of neuron projection development GO:0010975 15 14 0,000 0,04584119 0,07340166 ! aminoglycan biosynthetic process GO:0006023 14 14 0,000 0,04584119 0,07333795 ! vesicle docking GO:0048278 14 14 0,000 0,04584119 0,07327434 ! superoxide metabolic process GO:0006801 15 14 0,000 0,04584119 0,07321084 ! macromolecular complex disassembly GO:0032984 15 14 0,000 0,04584119 0,07314746 ! calcium-dependent cell-cell adhesion GO:0016339 14 14 0,000 0,04584119 0,07308418 ! mechanoreceptor differentiation GO:0042490 14 14 0,000 0,04584119 0,07302102 ! isoprenoid biosynthetic process GO:0008299 14 14 0,000 0,04584119 0,07295796 ! hair cycle GO:0042633 14 14 0,000 0,04584119 0,07289501 GO:0022404|molting cycle process, GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042303|molting cycle, ! negative regulation of epithelial cell proliferation GO:0050680 14 14 0,000 0,04584119 0,07283217 ! immune response-activating cell surface receptor signaling pathway GO:0002429 14 14 0,000 0,04584119 0,07276944 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! response to retinoic acid GO:0032526 14 14 0,000 0,04584119 0,07270681 GO:0033189|response to vitamin A, ! multicellular organismal response to stress GO:0033555 14 14 0,000 0,04584119 0,07264429 ! lysosome organization GO:0007040 14 14 0,000 0,04584119 0,07258189 ! actin polymerization or depolymerization GO:0008154 15 14 0,000 0,04584119 0,07251958 ! D-ribose metabolic process GO:0006014 14 14 0,000 0,04584119 0,07245739 ! negative regulation of phosphorus metabolic process GO:0010563 14 14 0,000 0,04584119 0,0723953 GO:0045936|negative regulation of phosphate metabolic process, ! peptide transport GO:0015833 14 14 0,000 0,04584119 0,07233332 ! primary neural tube formation GO:0014020 15 14 0,000 0,04584119 0,07227144 ! peptide cross-linking GO:0018149 14 14 0,000 0,04584119 0,07220967 ! regulation of behavior GO:0050795 14 14 0,000 0,04584119 0,07214801 ! vitamin biosynthetic process GO:0009110 14 14 0,000 0,04584119 0,07208645 ! base-excision repair GO:0006284 14 14 0,000 0,04584119 0,07202499 ! response to organic cyclic substance GO:0014070 15 14 0,000 0,04584119 0,07196364 ! leukotriene metabolic process GO:0006691 14 14 0,000 0,04584119 0,0719024 ! regulation of vasoconstriction GO:0019229 14 14 0,000 0,04584119 0,07184125 ! formation of primary germ layer GO:0001704 14 14 0,000 0,04584119 0,07178022 GO:0001707|mesoderm formation, ! collagen fibril organization GO:0030199 14 14 0,000 0,04584119 0,07171928 ! proteoglycan biosynthetic process GO:0030166 14 14 0,000 0,04584119 0,07165845 ! regulation of blood coagulation GO:0030193 15 14 0,000 0,04584119 0,07159772 ! positive regulation of inflammatory response GO:0050729 14 14 0,000 0,04584119 0,0715371 ! group transfer coenzyme metabolic process GO:0006752 14 14 0,000 0,04584119 0,07147658 ! positive regulation of osteoblast differentiation GO:0045669 14 14 0,000 0,04584119 0,07141616 ! neuromuscular process controlling balance GO:0050885 14 14 0,000 0,04584119 0,07135584 ! aspartate family amino acid metabolic process GO:0009066 14 14 0,000 0,04584119 0,07129562 ! response to molecule of bacterial origin GO:0002237 14 14 0,000 0,04584119 0,07123551 ! negative regulation of protein polymerization GO:0032272 14 14 0,000 0,04584119 0,0711755 ! protein import into nucleus, translocation GO:0000060 15 15 0,000 0,04903747 0,07607412 ! positive regulation of fibroblast proliferation GO:0048146 15 15 0,000 0,04903747 0,07601014 ! negative regulation of actin filament depolymerization GO:0030835 15 15 0,000 0,04903747 0,07594627 ! positive regulation of ossification GO:0045778 15 15 0,000 0,04903747 0,0758825 GO:0046852|positive regulation of bone remodeling, GO:0034105|positive regulation of tissue remodeling, ! negative regulation of protein complex assembly GO:0031333 15 15 0,000 0,04903747 0,07581884 ! protein amino acid O-linked glycosylation GO:0006493 15 15 0,000 0,04903747 0,07575529 ! cellular polysaccharide biosynthetic process GO:0033692 15 15 0,000 0,04903747 0,07569184 ! proteoglycan metabolic process GO:0006029 15 15 0,000 0,04903747 0,0756285 ! response to vitamin GO:0033273 15 15 0,000 0,04903747 0,07556527 ! regulation of transcription factor import into nucleus GO:0042990 15 15 0,000 0,04903747 0,07550214 ! striated muscle cell differentiation GO:0051146 16 15 0,000 0,04903747 0,07543911 ! odontogenesis of dentine-containing tooth GO:0042475 15 15 0,000 0,04903747 0,07537619 ! detection of stimulus involved in sensory perception GO:0050906 16 15 0,000 0,04903747 0,07531338 ! insulin receptor signaling pathway GO:0008286 17 15 0,000 0,04903747 0,07525067 ! ovarian follicle development GO:0001541 15 15 0,000 0,04903747 0,07518807 ! antigen processing and presentation of peptide antigen GO:0048002 15 15 0,000 0,04903747 0,07512557 ! regulation of smooth muscle contraction GO:0006940 15 15 0,000 0,04903747 0,07506317 ! deoxyribonucleotide metabolic process GO:0009262 15 15 0,000 0,04903747 0,07500088 ! complement activation, classical pathway GO:0006958 15 15 0,000 0,04903747 0,07493869 ! ER-nuclear signaling pathway GO:0006984 15 15 0,000 0,04903747 0,0748766 ! heme metabolic process GO:0042168 15 15 0,000 0,04903747 0,07481462 ! mesoderm morphogenesis GO:0048332 15 15 0,000 0,04903747 0,07475274 ! chromosome condensation GO:0030261 15 15 0,000 0,04903747 0,07469096 ! response to starvation GO:0042594 15 15 0,000 0,04903747 0,07462928 ! response to ionizing radiation GO:0010212 16 15 0,000 0,04903747 0,0745677 ! response to mechanical stimulus GO:0009612 15 15 0,000 0,04903747 0,07450623 ! hydrogen peroxide metabolic process GO:0042743 15 15 0,000 0,04903747 0,07444486 ! regulation of biomineral formation GO:0070167 15 15 0,000 0,04903747 0,07438359 GO:0030500|regulation of bone mineralization, ! regulation of production of molecular mediator of immune response GO:0002700 15 15 0,000 0,04903747 0,07432242 ! cyclic nucleotide biosynthetic process GO:0009190 15 15 0,000 0,04903747 0,07426135 ! cholesterol biosynthetic process GO:0006695 15 15 0,000 0,04903747 0,07420038 ! phospholipid transport GO:0015914 15 15 0,000 0,04903747 0,07413951 ! leukocyte homeostasis GO:0001776 15 15 0,000 0,04903747 0,07407874 ! regulation of cytokine secretion GO:0050707 15 15 0,000 0,04903747 0,07401806 ! glutathione metabolic process GO:0006749 16 15 0,000 0,04903747 0,07395749 ! nicotinamide metabolic process GO:0006769 15 15 0,000 0,04903747 0,07389702 GO:0046496|nicotinamide nucleotide metabolic process, ! positive regulation of B cell activation GO:0050871 15 15 0,000 0,04903747 0,07383665 ! positive regulation of myeloid cell differentiation GO:0045639 16 15 0,000 0,04903747 0,07377637 ! cellular alkene metabolic process GO:0043449 15 15 0,000 0,04903747 0,0737162 ! negative regulation of transcription factor activity GO:0043433 16 15 0,000 0,04903747 0,07365612 GO:0090048|negative regulation of transcription regulator activity, ! somatic diversification of immune receptors GO:0002200 15 15 0,000 0,04903747 0,07359614 ! protein homooligomerization GO:0051260 15 15 0,000 0,04903747 0,07353625 ! positive regulation of immune effector process GO:0002699 15 15 0,000 0,04903747 0,07347647 ! negative regulation of adenylate cyclase activity GO:0007194 16 16 0,000 0,05222351 0,07818678 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! alkaloid metabolic process GO:0009820 16 16 0,000 0,05222351 0,07812331 ! regulation of synaptic plasticity GO:0048167 16 16 0,000 0,05222351 0,07805995 ! spliceosomal snRNP biogenesis GO:0000387 16 16 0,000 0,05222351 0,0779967 ! learning GO:0007612 16 16 0,000 0,05222351 0,07793354 ! circadian rhythm GO:0007623 16 16 0,000 0,05222351 0,07787049 ! inner ear morphogenesis GO:0042472 16 16 0,000 0,05222351 0,07780754 ! positive regulation of mitosis GO:0045840 16 16 0,000 0,05222351 0,07774469 GO:0051785|positive regulation of nuclear division, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 16 16 0,000 0,05222351 0,07768194 ! vacuole organization GO:0007033 16 16 0,000 0,05222351 0,07761929 ! positive regulation of cytoskeleton organization GO:0051495 16 16 0,000 0,05222351 0,07755675 ! vesicle targeting GO:0006903 17 16 0,000 0,05222351 0,0774943 ! segmentation GO:0035282 17 16 0,000 0,05222351 0,07743196 ! fatty acid beta-oxidation GO:0006635 16 16 0,000 0,05222351 0,07736971 ! triglyceride metabolic process GO:0006641 16 16 0,000 0,05222351 0,07730757 ! iron ion homeostasis GO:0055072 16 16 0,000 0,05222351 0,07724552 ! positive regulation of cell development GO:0010720 16 16 0,000 0,05222351 0,07718358 ! regulation of myeloid leukocyte differentiation GO:0002761 17 16 0,000 0,05222351 0,07712173 ! lymphocyte proliferation GO:0046651 16 16 0,000 0,05222351 0,07705999 ! regulation of systemic arterial blood pressure GO:0003073 17 16 0,000 0,05222351 0,07699834 ! cell fate specification GO:0001708 16 16 0,000 0,05222351 0,07693679 ! pentose metabolic process GO:0019321 16 16 0,000 0,05222351 0,07687534 ! fatty acid transport GO:0015908 16 16 0,000 0,05222351 0,07681398 ! positive regulation of MAPKKK cascade GO:0043410 17 16 0,000 0,05222351 0,07675273 ! cellular response to nutrient levels GO:0031669 16 16 0,000 0,05222351 0,07669157 ! regulation of microtubule cytoskeleton organization GO:0070507 16 16 0,000 0,05222351 0,07663051 ! cofactor catabolic process GO:0051187 16 16 0,000 0,05222351 0,07656955 ! ethanolamine and derivative metabolic process GO:0042439 17 16 0,000 0,05222351 0,07650868 ! polyol metabolic process GO:0019751 16 16 0,000 0,05222351 0,07644791 ! serine family amino acid metabolic process GO:0009069 16 16 0,000 0,05222351 0,07638724 ! glutamine family amino acid catabolic process GO:0009065 17 16 0,000 0,05222351 0,07632666 ! porphyrin metabolic process GO:0006778 16 16 0,000 0,05222351 0,07626618 GO:0033013|tetrapyrrole metabolic process, ! embryonic epithelial tube formation GO:0001838 17 16 0,000 0,05222351 0,0762058 GO:0001841|neural tube formation, ! regulation of JUN kinase activity GO:0043506 17 16 0,000 0,05222351 0,07614551 GO:0043507|positive regulation of JUN kinase activity, ! regulation of cell morphogenesis involved in differentiation GO:0010769 17 16 0,000 0,05222351 0,07608531 ! response to xenobiotic stimulus GO:0009410 16 16 0,000 0,05222351 0,07602521 ! regulation of coagulation GO:0050818 17 16 0,000 0,05222351 0,07596521 ! regulation of fibroblast proliferation GO:0048145 17 17 0,000 0,05539933 0,08052127 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 17 17 0,000 0,05539933 0,08045781 ! regulation of smooth muscle cell proliferation GO:0048660 17 17 0,000 0,05539933 0,08039446 ! regulation of actin filament depolymerization GO:0030834 17 17 0,000 0,05539933 0,08033121 ! phosphoinositide biosynthetic process GO:0046489 17 17 0,000 0,05539933 0,08026806 ! regulation of transmembrane transport GO:0034762 17 17 0,000 0,05539933 0,080205 ! nucleotide-excision repair, DNA damage removal GO:0000718 18 17 0,000 0,05539933 0,08014205 ! leukocyte adhesion GO:0007159 17 17 0,000 0,05539933 0,08007919 ! sensory perception of smell GO:0007608 17 17 0,000 0,05539933 0,08001643 ! glucose transport GO:0015758 17 17 0,000 0,05539933 0,07995377 ! cell junction assembly GO:0034329 18 17 0,000 0,05539933 0,07989121 ! tissue remodeling GO:0048771 17 17 0,000 0,05539933 0,07982875 ! embryonic skeletal system morphogenesis GO:0048704 17 17 0,000 0,05539933 0,07976638 ! cellular carbohydrate biosynthetic process GO:0034637 17 17 0,000 0,05539933 0,07970411 ! development of primary male sexual characteristics GO:0046546 17 17 0,000 0,05539933 0,07964194 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 17 17 0,000 0,05539933 0,07957986 ! neural crest cell development GO:0014032 19 17 0,000 0,05539933 0,07951789 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 18 17 0,000 0,05539933 0,07945601 ! negative regulation of cell development GO:0010721 18 17 0,000 0,05539933 0,07939422 GO:0050768|negative regulation of neurogenesis, ! immune response-activating signal transduction GO:0002757 17 17 0,000 0,05539933 0,07933253 GO:0002764|immune response-regulating signal transduction, ! cell recognition GO:0008037 18 17 0,000 0,05539933 0,07927094 ! positive regulation of protein secretion GO:0050714 17 17 0,000 0,05539933 0,07920944 ! regulation of osteoblast differentiation GO:0045667 17 17 0,000 0,05539933 0,07914804 ! pyridine nucleotide metabolic process GO:0019362 17 17 0,000 0,05539933 0,07908673 ! pigmentation GO:0043473 17 17 0,000 0,05539933 0,07902552 ! myeloid leukocyte activation GO:0002274 18 17 0,000 0,05539933 0,0789644 ! adult locomotory behavior GO:0008344 17 17 0,000 0,05539933 0,07890337 ! embryonic organ development GO:0048568 17 17 0,000 0,05539933 0,07884245 ! regulation of calcium ion transport GO:0051924 17 17 0,000 0,05539933 0,07878161 ! liver development GO:0001889 17 17 0,000 0,05539933 0,07872087 ! gene silencing GO:0016458 17 17 0,000 0,05539933 0,07866022 ! mRNA export from nucleus GO:0006406 18 18 0,000 0,05856497 0,08309103 ! regulation of cell projection organization GO:0031344 19 18 0,000 0,05856497 0,08302711 ! regulation of cellular catabolic process GO:0031329 18 18 0,000 0,05856497 0,0829633 ! icosanoid biosynthetic process GO:0046456 18 18 0,000 0,05856497 0,08289958 ! meiosis I GO:0007127 18 18 0,000 0,05856497 0,08283595 ! regulation of metal ion transport GO:0010959 18 18 0,000 0,05856497 0,08277243 ! membrane docking GO:0022406 18 18 0,000 0,05856497 0,082709 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 18 18 0,000 0,05856497 0,08264567 ! mononuclear cell proliferation GO:0032943 18 18 0,000 0,05856497 0,08258244 GO:0070661|leukocyte proliferation, ! response to calcium ion GO:0051592 18 18 0,000 0,05856497 0,0825193 ! negative regulation of response to external stimulus GO:0032102 18 18 0,000 0,05856497 0,08245626 ! hexose transport GO:0008645 18 18 0,000 0,05856497 0,08239332 GO:0015749|monosaccharide transport, ! cholesterol homeostasis GO:0042632 18 18 0,000 0,05856497 0,08233047 GO:0055092|sterol homeostasis, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 18 18 0,000 0,05856497 0,08226772 ! striated muscle contraction GO:0006941 18 18 0,000 0,05856497 0,08220506 ! neutral lipid metabolic process GO:0006638 18 18 0,000 0,05856497 0,0821425 GO:0006639|acylglycerol metabolic process, ! negative regulation of DNA binding GO:0043392 19 18 0,000 0,05856497 0,08208004 ! ceramide metabolic process GO:0006672 18 18 0,000 0,05856497 0,08201767 GO:0046519|sphingoid metabolic process, ! ribonucleoside monophosphate metabolic process GO:0009161 18 18 0,000 0,05856497 0,08195539 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! telencephalon development GO:0021537 19 18 0,000 0,05856497 0,08189321 ! hexose biosynthetic process GO:0019319 18 18 0,000 0,05856497 0,08183112 ! negative regulation of MAP kinase activity GO:0043407 18 18 0,000 0,05856497 0,08176913 ! B cell differentiation GO:0030183 18 18 0,000 0,05856497 0,08170723 ! cellular response to extracellular stimulus GO:0031668 18 18 0,000 0,05856497 0,08164542 ! BMP signaling pathway GO:0030509 18 18 0,000 0,05856497 0,08158371 ! regulation of microtubule-based process GO:0032886 18 18 0,000 0,05856497 0,08152209 ! negative regulation of catabolic process GO:0009895 18 18 0,000 0,05856497 0,08146056 ! establishment of vesicle localization GO:0051650 19 18 0,000 0,05856497 0,08139913 ! DNA damage checkpoint GO:0000077 19 19 0,000 0,06172047 0,08572029 ! activation of adenylate cyclase activity GO:0007190 19 19 0,000 0,06172047 0,08565574 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 19 19 0,000 0,06172047 0,08559129 GO:0006956|complement activation, ! negative regulation of DNA metabolic process GO:0051053 19 19 0,000 0,06172047 0,08552694 ! glial cell differentiation GO:0010001 19 19 0,000 0,06172047 0,08546268 ! regulation of pH GO:0006885 19 19 0,000 0,06172047 0,08539852 ! feeding behavior GO:0007631 19 19 0,000 0,06172047 0,08533445 ! regulation of endothelial cell proliferation GO:0001936 19 19 0,000 0,06172047 0,08527048 ! peroxisome organization GO:0007031 19 19 0,000 0,06172047 0,08520661 ! positive regulation of T cell proliferation GO:0042102 19 19 0,000 0,06172047 0,08514283 ! regulation of striated muscle tissue development GO:0016202 20 19 0,000 0,06172047 0,08507915 ! metanephros development GO:0001656 19 19 0,000 0,06172047 0,08501556 ! ribonucleoside metabolic process GO:0009119 19 19 0,000 0,06172047 0,08495207 ! regulation of lymphocyte mediated immunity GO:0002706 19 19 0,000 0,06172047 0,08488868 ! positive regulation of T cell differentiation GO:0045582 19 19 0,000 0,06172047 0,08482537 ! regulation of protein stability GO:0031647 19 19 0,000 0,06172047 0,08476217 ! hormone biosynthetic process GO:0042446 19 19 0,000 0,06172047 0,08469905 ! biogenic amine biosynthetic process GO:0042401 20 19 0,000 0,06172047 0,08463603 ! dorsal/ventral pattern formation GO:0009953 19 19 0,000 0,06172047 0,0845731 ! eye morphogenesis GO:0048592 19 19 0,000 0,06172047 0,08451027 ! regulation of cell shape GO:0008360 21 19 0,000 0,06172047 0,08444753 ! placenta development GO:0001890 19 19 0,000 0,06172047 0,08438489 ! response to heat GO:0009408 19 19 0,000 0,06172047 0,08432233 ! vesicle localization GO:0051648 20 19 0,000 0,06172047 0,08425987 ! regulation of muscle development GO:0048634 21 20 0,000 0,06486585 0,08848835 ! negative regulation of cell adhesion GO:0007162 21 20 0,000 0,06486585 0,0884229 ! establishment or maintenance of cell polarity GO:0007163 21 20 0,000 0,06486585 0,08835754 ! negative regulation of binding GO:0051100 21 20 0,000 0,06486585 0,08829229 ! organic ether metabolic process GO:0018904 20 20 0,000 0,06486585 0,08822713 GO:0006662|glycerol ether metabolic process, ! cytoskeleton-dependent intracellular transport GO:0030705 20 20 0,000 0,06486585 0,08816206 ! neural tube development GO:0021915 21 20 0,000 0,06486585 0,08809709 ! nucleus organization GO:0006997 20 20 0,000 0,06486585 0,08803222 ! phagocytosis GO:0006909 21 20 0,000 0,06486585 0,08796744 ! positive regulation of gene-specific transcription GO:0043193 20 20 0,000 0,06486585 0,08790276 ! unsaturated fatty acid biosynthetic process GO:0006636 20 20 0,000 0,06486585 0,08783817 ! protein targeting to membrane GO:0006612 22 20 0,000 0,06486585 0,08777368 ! cyclic nucleotide metabolic process GO:0009187 20 20 0,000 0,06486585 0,08770928 ! chromatin remodeling GO:0006338 20 20 0,000 0,06486585 0,08764498 ! detection of abiotic stimulus GO:0009582 21 20 0,000 0,06486585 0,08758077 ! lipid oxidation GO:0034440 20 20 0,000 0,06486585 0,08751666 GO:0019395|fatty acid oxidation, ! female gamete generation GO:0007292 20 20 0,000 0,06486585 0,08745264 ! negative regulation of neuron apoptosis GO:0043524 21 20 0,000 0,06486585 0,08738871 ! monosaccharide biosynthetic process GO:0046364 20 20 0,000 0,06486585 0,08732488 ! RNA modification GO:0009451 20 20 0,000 0,06486585 0,08726113 ! regulation of B cell activation GO:0050864 20 20 0,000 0,06486585 0,08719749 ! mitotic sister chromatid segregation GO:0000070 21 21 0,000 0,06800114 0,09134555 ! positive regulation of adenylate cyclase activity GO:0045762 21 21 0,000 0,06800114 0,09127902 GO:0051349|positive regulation of lyase activity, GO:0031281|positive regulation of cyclase activity, ! protein amino acid lipidation GO:0006497 21 21 0,000 0,06800114 0,09121259 ! receptor-mediated endocytosis GO:0006898 21 21 0,000 0,06800114 0,09114625 ! Notch signaling pathway GO:0007219 22 21 0,000 0,06800114 0,09108001 ! morphogenesis of embryonic epithelium GO:0016331 22 21 0,000 0,06800114 0,09101387 ! ear morphogenesis GO:0042471 21 21 0,000 0,06800114 0,09094782 ! organic anion transport GO:0015711 21 21 0,000 0,06800114 0,09088187 ! cholesterol transport GO:0030301 21 21 0,000 0,06800114 0,09081601 GO:0015918|sterol transport, ! spliceosome assembly GO:0000245 22 21 0,000 0,06800114 0,09075025 ! regulation of Rab protein signal transduction GO:0032483 21 21 0,000 0,06800114 0,09068458 GO:0032313|regulation of Rab GTPase activity, ! DNA integrity checkpoint GO:0031570 21 21 0,000 0,06800114 0,09061901 ! regulation of protein import into nucleus GO:0042306 21 21 0,000 0,06800114 0,09055354 ! regulation of leukocyte mediated immunity GO:0002703 21 21 0,000 0,06800114 0,09048815 ! regulation of proteolysis GO:0030162 21 21 0,000 0,06800114 0,09042287 ! negative regulation of hydrolase activity GO:0051346 21 21 0,000 0,06800114 0,09035767 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 21 21 0,000 0,06800114 0,09029257 ! cellular response to insulin stimulus GO:0032869 23 21 0,000 0,06800114 0,09022757 ! positive regulation of transcription factor activity GO:0051091 22 22 0,000 0,07112637 0,0943064 GO:0090047|positive regulation of transcription regulator activity, ! RNA export from nucleus GO:0006405 22 22 0,000 0,07112637 0,0942386 ! positive regulation of DNA metabolic process GO:0051054 23 22 0,000 0,07112637 0,0941709 ! sister chromatid segregation GO:0000819 22 22 0,000 0,07112637 0,0941033 ! regulation of ion transport GO:0043269 22 22 0,000 0,07112637 0,09403579 ! odontogenesis GO:0042476 22 22 0,000 0,07112637 0,09396839 ! cell junction organization GO:0034330 23 22 0,000 0,07112637 0,09390107 ! positive regulation of lymphocyte proliferation GO:0050671 22 22 0,000 0,07112637 0,09383386 GO:0032946|positive regulation of mononuclear cell proliferation, GO:0070665|positive regulation of leukocyte proliferation, GO:0070668|positive regulation of mast cell proliferation, ! hormone-mediated signaling GO:0009755 22 22 0,000 0,07112637 0,09376674 ! embryonic skeletal system development GO:0048706 22 22 0,000 0,07112637 0,09369971 ! maintenance of protein location in cell GO:0032507 23 22 0,000 0,07112637 0,09363278 ! ovulation cycle process GO:0022602 22 22 0,000 0,07112637 0,09356595 ! spindle organization GO:0007051 22 22 0,000 0,07112637 0,09349921 ! pigment biosynthetic process GO:0046148 22 22 0,000 0,07112637 0,09343257 ! cell chemotaxis GO:0060326 23 22 0,000 0,07112637 0,09336602 GO:0030595|leukocyte chemotaxis, ! respiratory gaseous exchange GO:0007585 22 22 0,000 0,07112637 0,09329957 ! erythrocyte differentiation GO:0030218 23 22 0,000 0,07112637 0,09323321 ! male sex differentiation GO:0046661 22 22 0,000 0,07112637 0,09316695 ! sterol biosynthetic process GO:0016126 22 22 0,000 0,07112637 0,09310078 ! regulation of adaptive immune response GO:0002819 22 22 0,000 0,07112637 0,0930347 ! detection of external stimulus GO:0009581 23 22 0,000 0,07112637 0,09296872 ! regulation of Wnt receptor signaling pathway GO:0030111 23 22 0,000 0,07112637 0,09290283 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 22 22 0,000 0,07112637 0,09283704 ! positive regulation of lymphocyte differentiation GO:0045621 22 22 0,000 0,07112637 0,09277134 ! fatty acid catabolic process GO:0009062 23 22 0,000 0,07112637 0,09270573 ! aerobic respiration GO:0009060 22 22 0,000 0,07112637 0,09264021 ! cytokine production GO:0001816 22 22 0,000 0,07112637 0,09257479 ! cytokinesis GO:0000910 23 22 0,000 0,07112637 0,09250946 ! pyrimidine nucleotide metabolic process GO:0006220 22 22 0,000 0,07112637 0,09244422 ! response to hydrogen peroxide GO:0042542 24 23 0,000 0,07424158 0,09642511 ! epithelial cell differentiation GO:0030855 23 23 0,000 0,07424158 0,0963572 ! viral infectious cycle GO:0019058 23 23 0,000 0,07424158 0,09628939 ! regulation of hormone secretion GO:0046883 23 23 0,000 0,07424158 0,09622168 ! response to estrogen stimulus GO:0043627 23 23 0,000 0,07424158 0,09615406 ! negative regulation of protein complex disassembly GO:0043242 23 23 0,000 0,07424158 0,09608653 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 23 23 0,000 0,07424158 0,09601911 ! mitotic cell cycle checkpoint GO:0007093 24 23 0,000 0,07424158 0,09595177 ! induction of apoptosis by extracellular signals GO:0008624 23 23 0,000 0,07424158 0,09588453 ! regulation of ARF protein signal transduction GO:0032012 23 23 0,000 0,07424158 0,09581738 ! endocrine system development GO:0035270 23 23 0,000 0,07424158 0,09575033 ! lipoprotein biosynthetic process GO:0042158 23 23 0,000 0,07424158 0,09568337 ! female gonad development GO:0008585 23 23 0,000 0,07424158 0,09561651 ! monovalent inorganic cation homeostasis GO:0055067 23 23 0,000 0,07424158 0,09554974 ! lipid homeostasis GO:0055088 23 23 0,000 0,07424158 0,09548306 ! Rho protein signal transduction GO:0007266 24 23 0,000 0,07424158 0,09541648 ! regulation of JNK cascade GO:0046328 25 23 0,000 0,07424158 0,09534998 ! cell projection assembly GO:0030031 25 23 0,000 0,07424158 0,09528358 ! mitochondrial transport GO:0006839 24 24 0,000 0,07734679 0,09919981 ! gliogenesis GO:0042063 24 24 0,000 0,07734679 0,09913083 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 26 24 0,000 0,07734679 0,09906194 ! cellular amino acid biosynthetic process GO:0008652 24 24 0,000 0,07734679 0,09899315 ! glucose homeostasis GO:0042593 24 24 0,000 0,07734679 0,09892445 GO:0033500|carbohydrate homeostasis, ! heterocycle biosynthetic process GO:0018130 24 24 0,000 0,07734679 0,09885585 ! T cell differentiation GO:0030217 24 24 0,000 0,07734679 0,09878734 ! nucleotide catabolic process GO:0009166 24 24 0,000 0,07734679 0,09871893 ! erythrocyte homeostasis GO:0034101 25 24 0,000 0,07734679 0,09865061 ! ovulation cycle GO:0042698 24 24 0,000 0,07734679 0,09858239 ! maintenance of protein location GO:0045185 25 24 0,000 0,07734679 0,09851426 ! oxidoreduction coenzyme metabolic process GO:0006733 24 24 0,000 0,07734679 0,09844622 ! androgen receptor signaling pathway GO:0030521 24 24 0,000 0,07734679 0,09837828 ! epithelial tube morphogenesis GO:0060562 25 24 0,000 0,07734679 0,09831044 ! glucan metabolic process GO:0044042 25 24 0,000 0,07734679 0,09824268 GO:0006073|cellular glucan metabolic process, GO:0005977|glycogen metabolic process, ! regulation of actin filament polymerization GO:0030833 25 25 0,000 0,08044204 0,10210377 ! negative regulation of secretion GO:0051048 26 25 0,000 0,08044204 0,1020335 ! protein amino acid N-linked glycosylation GO:0006487 25 25 0,000 0,08044204 0,10196333 ! regulation of gene-specific transcription GO:0032583 25 25 0,000 0,08044204 0,10189325 ! sensory perception of chemical stimulus GO:0007606 25 25 0,000 0,08044204 0,10182327 ! cellular component disassembly GO:0022411 26 25 0,000 0,08044204 0,10175338 ! endosome transport GO:0016197 25 25 0,000 0,08044204 0,10168359 ! alcohol biosynthetic process GO:0046165 25 25 0,000 0,08044204 0,1016139 ! development of primary female sexual characteristics GO:0046545 25 25 0,000 0,08044204 0,1015443 GO:0046660|female sex differentiation, ! polysaccharide biosynthetic process GO:0000271 25 25 0,000 0,08044204 0,10147479 ! excretion GO:0007588 25 25 0,000 0,08044204 0,10140539 ! generation of a signal involved in cell-cell signaling GO:0003001 27 25 0,000 0,08044204 0,10133607 ! gastrulation GO:0007369 25 25 0,000 0,08044204 0,10126685 ! heart morphogenesis GO:0003007 25 25 0,000 0,08044204 0,10119773 ! icosanoid metabolic process GO:0006690 25 25 0,000 0,08044204 0,1011287 ! regulation of endocytosis GO:0030100 25 25 0,000 0,08044204 0,10105977 ! positive regulation of cytokine production GO:0001819 25 25 0,000 0,08044204 0,10099092 ! positive regulation of defense response GO:0031349 26 26 0,000 0,08352735 0,104793 ! glycolysis GO:0006096 26 26 0,000 0,08352735 0,10472171 ! transforming growth factor beta receptor signaling pathway GO:0007179 26 26 0,000 0,08352735 0,10465052 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 26 26 0,000 0,08352735 0,10457942 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 26 26 0,000 0,08352735 0,10450843 ! negative regulation of cell migration GO:0030336 26 26 0,000 0,08352735 0,10443752 ! induction of apoptosis by intracellular signals GO:0008629 26 26 0,000 0,08352735 0,10436672 ! cellular defense response GO:0006968 26 26 0,000 0,08352735 0,10429601 ! positive regulation of cytokine biosynthetic process GO:0042108 26 26 0,000 0,08352735 0,1042254 ! double-strand break repair GO:0006302 27 26 0,000 0,08352735 0,10415488 ! regulation of protein secretion GO:0050708 26 26 0,000 0,08352735 0,10408446 ! germ cell development GO:0007281 27 26 0,000 0,08352735 0,10401413 ! regulation of blood vessel size GO:0050880 27 26 0,000 0,08352735 0,1039439 GO:0035150|regulation of tube size, ! pigment metabolic process GO:0042440 26 26 0,000 0,08352735 0,10387376 ! response to insulin stimulus GO:0032868 28 26 0,000 0,08352735 0,10380372 ! maintenance of location in cell GO:0051651 27 26 0,000 0,08352735 0,10373377 ! chloride transport GO:0006821 27 27 0,000 0,08660276 0,10748074 ! regulation of neurotransmitter levels GO:0001505 31 27 0,000 0,08660276 0,10740841 ! energy reserve metabolic process GO:0006112 28 27 0,000 0,08660276 0,10733618 ! learning or memory GO:0007611 28 27 0,000 0,08660276 0,10726404 ! monocarboxylic acid transport GO:0015718 27 27 0,000 0,08660276 0,107192 ! cAMP-mediated signaling GO:0019933 27 27 0,000 0,08660276 0,10712006 ! peptide metabolic process GO:0006518 29 27 0,000 0,08660276 0,10704822 ! activation of caspase activity GO:0006919 27 27 0,000 0,08660276 0,10697647 ! mesenchymal cell development GO:0014031 29 27 0,000 0,08660276 0,10690482 GO:0060485|mesenchyme development, GO:0048762|mesenchymal cell differentiation, ! inner ear development GO:0048839 27 27 0,000 0,08660276 0,10683326 ! defense response to bacterium GO:0042742 27 27 0,000 0,08660276 0,1067618 ! isoprenoid metabolic process GO:0006720 27 27 0,000 0,08660276 0,10669044 ! glutamine family amino acid metabolic process GO:0009064 28 27 0,000 0,08660276 0,10661917 ! cell growth GO:0016049 27 27 0,000 0,08660276 0,10654799 ! stress-activated protein kinase signaling pathway GO:0031098 28 28 0,000 0,0896683 0,11024595 GO:0007254|JNK cascade, ! neuromuscular process GO:0050905 28 28 0,000 0,0896683 0,11017245 ! carbohydrate transport GO:0008643 28 28 0,000 0,0896683 0,11009906 ! regulation of muscle contraction GO:0006937 28 28 0,000 0,0896683 0,11002575 ! unsaturated fatty acid metabolic process GO:0033559 28 28 0,000 0,0896683 0,10995255 ! sulfur compound biosynthetic process GO:0044272 28 28 0,000 0,0896683 0,10987944 ! keratinocyte differentiation GO:0030216 28 28 0,000 0,0896683 0,10980643 ! developmental growth GO:0048589 28 28 0,000 0,0896683 0,10973352 ! cartilage development GO:0051216 29 28 0,000 0,0896683 0,1096607 ! glycerophospholipid biosynthetic process GO:0046474 30 29 0,000 0,092724 0,1133225 ! phosphoinositide metabolic process GO:0030384 29 29 0,000 0,092724 0,1132474 ! leukocyte migration GO:0050900 30 29 0,000 0,092724 0,1131724 ! branching morphogenesis of a tube GO:0048754 29 29 0,000 0,092724 0,1130975 ! antigen processing and presentation GO:0019882 29 29 0,000 0,092724 0,1130227 ! DNA-dependent DNA replication GO:0006261 29 29 0,000 0,092724 0,112948 ! tRNA processing GO:0008033 29 29 0,000 0,092724 0,1128734 ! adult behavior GO:0030534 30 29 0,000 0,092724 0,1127989 ! regulation of protein polymerization GO:0032271 29 29 0,000 0,092724 0,11272449 ! positive regulation of protein transport GO:0051222 29 29 0,000 0,092724 0,11265018 ! ER to Golgi vesicle-mediated transport GO:0006888 30 30 0,000 0,09576988 0,11627397 ! positive regulation of peptidase activity GO:0010952 30 30 0,000 0,09576988 0,11619743 GO:0043280|positive regulation of caspase activity, ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 30 30 0,000 0,09576988 0,11612098 ! neuropeptide signaling pathway GO:0007218 30 30 0,000 0,09576988 0,11604464 ! regulation of protein complex disassembly GO:0043244 30 30 0,000 0,09576988 0,11596839 ! positive regulation of response to external stimulus GO:0032103 30 30 0,000 0,09576988 0,11589225 ! skeletal system morphogenesis GO:0048705 31 30 0,000 0,09576988 0,1158162 ! response to temperature stimulus GO:0009266 30 30 0,000 0,09576988 0,11574026 ! regulation of ossification GO:0030278 30 30 0,000 0,09576988 0,11566441 ! vascular process in circulatory system GO:0003018 31 30 0,000 0,09576988 0,11558867 ! immunoglobulin mediated immune response GO:0016064 30 30 0,000 0,09576988 0,11551302 GO:0019724|B cell mediated immunity, ! regulation of inflammatory response GO:0050727 30 30 0,000 0,09576988 0,11543747 ! water-soluble vitamin metabolic process GO:0006767 30 30 0,000 0,09576988 0,11536202 ! vesicle organization GO:0016050 30 30 0,000 0,09576988 0,11528667 ! cellular amino acid derivative biosynthetic process GO:0042398 31 30 0,000 0,09576988 0,11521142 ! establishment of organelle localization GO:0051656 31 30 0,000 0,09576988 0,11513626 ! regulation of translational initiation GO:0006446 31 31 0,000 0,09880598 0,11870888 ! membrane fusion GO:0006944 31 31 0,000 0,09880598 0,11863155 ! B cell activation GO:0042113 31 31 0,000 0,09880598 0,11855431 ! negative regulation of cytoskeleton organization GO:0051494 32 31 0,000 0,09880598 0,11847718 ! lipoprotein metabolic process GO:0042157 31 31 0,000 0,09880598 0,11840015 ! ion transmembrane transport GO:0034220 31 31 0,000 0,09880598 0,11832321 GO:0015985|energy coupled proton transport, down electrochemical gradient, GO:0015986|ATP synthesis coupled proton transport, ! aging GO:0007568 32 31 0,000 0,09880598 0,11824638 ! glycerolipid biosynthetic process GO:0045017 32 31 0,000 0,09880598 0,11816965 ! digestion GO:0007586 31 31 0,000 0,09880598 0,11809301 ! nucleoside metabolic process GO:0009116 31 31 0,000 0,09880598 0,11801648 ! regulation of DNA replication GO:0006275 32 31 0,000 0,09880598 0,11794004 ! regulation of heart contraction GO:0008016 31 31 0,000 0,09880598 0,11786371 ! sphingolipid metabolic process GO:0006665 31 31 0,000 0,09880598 0,11778747 ! camera-type eye development GO:0043010 31 31 0,000 0,09880598 0,11771133 ! extracellular matrix organization GO:0030198 31 31 0,000 0,09880598 0,11763529 ! ribonucleoprotein complex assembly GO:0022618 32 31 0,000 0,09880598 0,11755935 ! epidermal cell differentiation GO:0009913 31 31 0,000 0,09880598 0,1174835 ! regulation of myeloid cell differentiation GO:0045637 32 31 0,000 0,09880598 0,11740775 ! negative regulation of cell motion GO:0051271 31 31 0,000 0,09880598 0,11733211 ! negative regulation of cell growth GO:0030308 32 32 0,000 0,10183233 0,12084803 ! cell redox homeostasis GO:0045454 32 32 0,000 0,10183233 0,12077026 ! glucose catabolic process GO:0006007 32 32 0,000 0,10183233 0,1206926 ! lipid modification GO:0030258 32 32 0,000 0,10183233 0,12061503 ! glycosaminoglycan metabolic process GO:0030203 34 32 0,000 0,10183233 0,12053756 ! regulation of vesicle-mediated transport GO:0060627 33 32 0,000 0,10183233 0,1204602 ! cell maturation GO:0048469 32 32 0,000 0,10183233 0,12038293 ! morphogenesis of a branching structure GO:0001763 32 32 0,000 0,10183233 0,12030576 ! nuclear export GO:0051168 32 32 0,000 0,10183233 0,12022869 ! kidney development GO:0001822 32 32 0,000 0,10183233 0,12015172 ! protein maturation by peptide bond cleavage GO:0051605 32 32 0,000 0,10183233 0,12007485 ! maintenance of location GO:0051235 33 32 0,000 0,10183233 0,11999807 ! negative regulation of cell size GO:0045792 33 33 0,000 0,10484896 0,12347389 ! regulation of cellular response to stress GO:0080135 35 33 0,000 0,10484896 0,12339504 ! amino acid transport GO:0006865 33 33 0,000 0,10484896 0,12331629 ! membrane lipid metabolic process GO:0006643 33 33 0,000 0,10484896 0,12323765 ! regulation of actin polymerization or depolymerization GO:0008064 33 33 0,000 0,10484896 0,1231591 ! regulation of neuron differentiation GO:0045664 34 33 0,000 0,10484896 0,12308066 ! regulation of neuron apoptosis GO:0043523 34 33 0,000 0,10484896 0,12300231 ! regulation of synaptic transmission GO:0050804 33 33 0,000 0,10484896 0,12292407 ! regulation of actin filament length GO:0030832 34 34 0,000 0,10785589 0,12636898 ! regulation of bone remodeling GO:0046850 34 34 0,000 0,10785589 0,1262887 ! response to metal ion GO:0010038 34 34 0,000 0,10785589 0,12620851 ! ear development GO:0043583 34 34 0,000 0,10785589 0,12612843 ! muscle cell differentiation GO:0042692 35 34 0,000 0,10785589 0,12604845 ! cellular polysaccharide metabolic process GO:0044264 35 34 0,000 0,10785589 0,12596857 ! coenzyme biosynthetic process GO:0009108 34 34 0,000 0,10785589 0,1258888 ! nucleoside monophosphate biosynthetic process GO:0009124 34 34 0,000 0,10785589 0,12580912 ! regulation of lipid metabolic process GO:0019216 34 34 0,000 0,10785589 0,12572954 ! secondary metabolic process GO:0019748 34 34 0,000 0,10785589 0,12565007 ! response to peptide hormone stimulus GO:0043434 36 34 0,000 0,10785589 0,12557069 ! negative regulation of response to stimulus GO:0048585 34 34 0,000 0,10785589 0,12549142 ! detection of stimulus GO:0051606 36 34 0,000 0,10785589 0,12541225 ! acute inflammatory response GO:0002526 35 35 0,000 0,11085316 0,12881613 ! regulation of cellular component size GO:0032535 35 35 0,000 0,11085316 0,12873496 ! regulation of cytokine biosynthetic process GO:0042035 35 35 0,000 0,11085316 0,12865389 ! mesoderm development GO:0007498 35 35 0,000 0,11085316 0,12857293 ! multicellular organism reproduction GO:0032504 36 35 0,000 0,11085316 0,12849206 GO:0048609|reproductive process in a multicellular organism, ! regulation of cell morphogenesis GO:0022604 38 35 0,000 0,11085316 0,1284113 ! regulation of tissue remodeling GO:0034103 35 35 0,000 0,11085316 0,12833064 ! inorganic anion transport GO:0015698 35 35 0,000 0,11085316 0,12825008 ! response to steroid hormone stimulus GO:0048545 35 35 0,000 0,11085316 0,12816962 ! regulation of immune effector process GO:0002697 35 35 0,000 0,11085316 0,12808927 ! hydrogen transport GO:0006818 36 36 0,000 0,1138408 0,13145902 GO:0015992|proton transport, ! response to inorganic substance GO:0010035 36 36 0,000 0,1138408 0,1313767 ! aminoglycan metabolic process GO:0006022 38 36 0,000 0,1138408 0,13129449 ! oxygen and reactive oxygen species metabolic process GO:0006800 37 36 0,000 0,1138408 0,13121238 ! regulation of mitosis GO:0007088 37 36 0,000 0,1138408 0,13113037 GO:0051783|regulation of nuclear division, ! embryonic limb morphogenesis GO:0030326 36 36 0,000 0,1138408 0,13104847 GO:0035113|embryonic appendage morphogenesis, ! female pregnancy GO:0007565 37 36 0,000 0,1138408 0,13096666 ! RNA elongation from RNA polymerase II promoter GO:0006368 36 36 0,000 0,1138408 0,13088496 ! positive regulation of organelle organization GO:0010638 36 36 0,000 0,1138408 0,13080336 ! heterocycle catabolic process GO:0046700 36 36 0,000 0,1138408 0,13072187 ! integrin-mediated signaling pathway GO:0007229 36 36 0,000 0,1138408 0,13064047 ! regulation of transmission of nerve impulse GO:0051969 36 36 0,000 0,1138408 0,13055917 ! gonad development GO:0008406 36 36 0,000 0,1138408 0,13047798 ! activation of immune response GO:0002253 36 36 0,000 0,1138408 0,13039689 ! coagulation GO:0050817 39 36 0,000 0,1138408 0,1303159 GO:0007596|blood coagulation, ! regulation of adenylate cyclase activity GO:0045761 37 37 0,000 0,11681883 0,13364191 GO:0031279|regulation of cyclase activity, GO:0051339|regulation of lyase activity, ! regulation of transcription factor activity GO:0051090 38 37 0,000 0,11681883 0,133559 GO:0090046|regulation of transcription regulator activity, ! meiosis GO:0007126 37 37 0,000 0,11681883 0,1334762 GO:0051327|M phase of meiotic cell cycle, ! lung development GO:0030324 38 37 0,000 0,11681883 0,1333935 ! lymphocyte mediated immunity GO:0002449 37 37 0,000 0,11681883 0,1333109 ! eye development GO:0001654 37 37 0,000 0,11681883 0,13322841 ! negative regulation of growth GO:0045926 37 37 0,000 0,11681883 0,13314602 ! DNA damage response, signal transduction GO:0042770 37 37 0,000 0,11681883 0,13306373 ! ATP synthesis coupled electron transport GO:0042773 37 37 0,000 0,11681883 0,13298154 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! cellular amino acid catabolic process GO:0009063 38 37 0,000 0,11681883 0,13289945 ! regulation of Rho protein signal transduction GO:0035023 37 37 0,000 0,11681883 0,13281746 ! adaptive immune response GO:0002250 37 37 0,000 0,11681883 0,13273558 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! positive regulation of secretion GO:0051047 39 38 0,000 0,11978729 0,13602463 ! neurotransmitter transport GO:0006836 40 38 0,000 0,11978729 0,13594087 ! cellular hormone metabolic process GO:0034754 39 38 0,000 0,11978729 0,13585722 ! exocytosis GO:0006887 40 38 0,000 0,11978729 0,13577367 ! cell-matrix adhesion GO:0007160 39 38 0,000 0,11978729 0,13569022 ! chromosome segregation GO:0007059 38 38 0,000 0,11978729 0,13560687 ! urogenital system development GO:0001655 38 38 0,000 0,11978729 0,13552362 ! hexose catabolic process GO:0019320 38 38 0,000 0,11978729 0,13544048 ! RNA elongation GO:0006354 38 38 0,000 0,11978729 0,13535744 ! meiotic cell cycle GO:0051321 38 38 0,000 0,11978729 0,1352745 ! regulation of neurological system process GO:0031644 38 38 0,000 0,11978729 0,13519166 ! steroid hormone receptor signaling pathway GO:0030518 38 38 0,000 0,11978729 0,13510892 ! regulation of homeostatic process GO:0032844 38 38 0,000 0,11978729 0,13502629 ! regulation of cAMP biosynthetic process GO:0030817 39 39 0,000 0,12274621 0,13827705 ! hemostasis GO:0007599 42 39 0,000 0,12274621 0,13819258 ! respiratory tube development GO:0030323 40 39 0,000 0,12274621 0,13810822 ! response to unfolded protein GO:0006986 39 39 0,000 0,12274621 0,13802395 ! nucleoside monophosphate metabolic process GO:0009123 39 39 0,000 0,12274621 0,13793979 ! fatty acid biosynthetic process GO:0006633 39 39 0,000 0,12274621 0,13785573 ! nucleotide-excision repair GO:0006289 40 39 0,000 0,12274621 0,13777178 ! cytokine-mediated signaling pathway GO:0019221 39 39 0,000 0,12274621 0,13768792 ! regulation of MAPKKK cascade GO:0043408 41 39 0,000 0,12274621 0,13760417 ! positive regulation of T cell activation GO:0050870 39 39 0,000 0,12274621 0,13752052 ! respiratory system development GO:0060541 40 39 0,000 0,12274621 0,13743697 ! developmental maturation GO:0021700 39 39 0,000 0,12274621 0,13735353 ! lymphocyte differentiation GO:0030098 39 39 0,000 0,12274621 0,13727018 ! limb development GO:0060173 39 39 0,000 0,12274621 0,13718694 GO:0048736|appendage development, GO:0035107|appendage morphogenesis, ! protein oligomerization GO:0051259 39 39 0,000 0,12274621 0,13710379 ! regulation of cAMP metabolic process GO:0030814 40 40 0,000 0,12569561 0,14031314 ! DNA catabolic process GO:0006308 41 40 0,000 0,12569561 0,14022821 ! intracellular receptor-mediated signaling pathway GO:0030522 40 40 0,000 0,12569561 0,14014338 ! myeloid cell differentiation GO:0030099 42 40 0,000 0,12569561 0,14005865 ! organelle localization GO:0051640 41 40 0,000 0,12569561 0,13997402 ! regulation of nucleotide biosynthetic process GO:0030808 41 41 0,000 0,12863552 0,14316139 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! cell cycle checkpoint GO:0000075 42 41 0,000 0,12863552 0,14307499 ! amine catabolic process GO:0009310 42 41 0,000 0,12863552 0,1429887 ! elevation of cytosolic calcium ion concentration GO:0007204 41 41 0,000 0,12863552 0,14290251 ! regulation of caspase activity GO:0043281 41 41 0,000 0,12863552 0,14281642 ! phospholipid biosynthetic process GO:0008654 42 41 0,000 0,12863552 0,14273044 ! leukocyte mediated immunity GO:0002443 41 41 0,000 0,12863552 0,14264456 ! regulation of Ras GTPase activity GO:0032318 41 41 0,000 0,12863552 0,14255879 ! monosaccharide catabolic process GO:0046365 41 41 0,000 0,12863552 0,14247311 ! respiratory electron transport chain GO:0022904 43 42 0,000 0,13156597 0,14563128 ! regulation of cyclic nucleotide metabolic process GO:0030799 42 42 0,000 0,13156597 0,14554387 ! regulation of endopeptidase activity GO:0052548 42 42 0,000 0,13156597 0,14545656 ! cytosolic calcium ion homeostasis GO:0051480 42 42 0,000 0,13156597 0,14536936 ! cell-substrate adhesion GO:0031589 43 42 0,000 0,13156597 0,14528226 ! development of primary sexual characteristics GO:0045137 42 42 0,000 0,13156597 0,14519526 ! negative regulation of ligase activity GO:0051352 43 42 0,000 0,13156597 0,14510837 GO:0051444|negative regulation of ubiquitin-protein ligase activity, GO:0051436|negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle, ! response to protein stimulus GO:0051789 42 42 0,000 0,13156597 0,14502158 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 42 42 0,000 0,13156597 0,1449349 ! reproductive structure development GO:0048608 43 43 0,000 0,134487 0,14806424 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 43 43 0,000 0,134487 0,14797585 ! mitochondrion organization GO:0007005 44 43 0,000 0,134487 0,14788755 ! alcohol catabolic process GO:0046164 43 43 0,000 0,134487 0,14779937 ! homeostasis of number of cells GO:0048872 44 43 0,000 0,134487 0,14771129 ! regulation of nucleotide metabolic process GO:0006140 43 43 0,000 0,134487 0,14762331 ! humoral immune response GO:0006959 44 44 0,000 0,13739863 0,15072957 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 45 44 0,000 0,13739863 0,1506399 ! negative regulation of organelle organization GO:0010639 45 44 0,000 0,13739863 0,15055034 ! vitamin metabolic process GO:0006766 44 44 0,000 0,13739863 0,15046089 ! positive regulation of lymphocyte activation GO:0051251 44 44 0,000 0,13739863 0,15037154 ! amine biosynthetic process GO:0009309 46 45 0,000 0,14030089 0,1534567 ! homophilic cell adhesion GO:0007156 45 45 0,000 0,14030089 0,15336568 ! regulation of actin cytoskeleton organization GO:0032956 46 45 0,000 0,14030089 0,15327477 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 46 45 0,000 0,14030089 0,15318396 ! steroid biosynthetic process GO:0006694 46 45 0,000 0,14030089 0,15309327 ! Wnt receptor signaling pathway GO:0016055 46 45 0,000 0,14030089 0,15300268 ! protein processing GO:0016485 45 45 0,000 0,14030089 0,1529122 ! regulation of actin filament-based process GO:0032970 47 46 0,000 0,1431938 0,15597292 ! cyclic-nucleotide-mediated signaling GO:0019935 46 46 0,000 0,1431938 0,15588079 ! tube morphogenesis GO:0035239 47 46 0,000 0,1431938 0,15578877 ! regulation of peptidase activity GO:0052547 46 46 0,000 0,1431938 0,15569686 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 47 46 0,000 0,1431938 0,15560506 ! transcription initiation from RNA polymerase II promoter GO:0006367 46 46 0,000 0,1431938 0,15551336 ! positive regulation of ligase activity GO:0051351 47 46 0,000 0,1431938 0,15542178 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 47 47 0,000 0,1460774 0,1584583 ! regulation of blood pressure GO:0008217 48 47 0,000 0,1460774 0,15836509 ! sex differentiation GO:0007548 47 47 0,000 0,1460774 0,15827199 ! amine transport GO:0015837 47 47 0,000 0,1460774 0,158179 ! rhythmic process GO:0048511 47 47 0,000 0,1460774 0,15808612 ! calcium ion transport GO:0006816 48 48 0,000 0,14895172 0,16110213 ! actin filament organization GO:0007015 50 48 0,000 0,14895172 0,16100764 ! regulation of ubiquitin-protein ligase activity GO:0051438 49 48 0,000 0,14895172 0,16091326 ! regulation of cell cycle process GO:0010564 50 48 0,000 0,14895172 0,160819 ! glycerophospholipid metabolic process GO:0006650 49 48 0,000 0,14895172 0,16072484 ! DNA recombination GO:0006310 48 48 0,000 0,14895172 0,16063079 ! leukocyte differentiation GO:0002521 50 49 0,000 0,15181679 0,16362476 ! cellular lipid catabolic process GO:0044242 50 49 0,000 0,15181679 0,16352913 ! divalent metal ion transport GO:0070838 49 49 0,000 0,15181679 0,16343361 ! response to nutrient GO:0007584 49 49 0,000 0,15181679 0,1633382 ! response to bacterium GO:0009617 50 49 0,000 0,15181679 0,1632429 ! regulation of ligase activity GO:0051340 50 49 0,000 0,15181679 0,16314772 ! cofactor biosynthetic process GO:0051188 49 49 0,000 0,15181679 0,16305264 ! positive regulation of cell activation GO:0050867 49 49 0,000 0,15181679 0,16295768 GO:0002696|positive regulation of leukocyte activation, ! regulation of defense response GO:0031347 50 50 0,000 0,15467262 0,16592645 ! regulation of DNA metabolic process GO:0051052 51 50 0,000 0,15467262 0,16582993 ! chromatin assembly GO:0031497 50 50 0,000 0,15467262 0,16573351 GO:0006334|nucleosome assembly, ! T cell activation GO:0042110 51 50 0,000 0,15467262 0,16563721 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 50 50 0,000 0,15467262 0,16554102 ! nitrogen compound catabolic process GO:0044270 51 50 0,000 0,15467262 0,16544495 ! regulation of neurogenesis GO:0050767 51 50 0,000 0,15467262 0,16534898 ! transcription initiation GO:0006352 50 50 0,000 0,15467262 0,16525313 ! anterior/posterior pattern formation GO:0009952 51 50 0,000 0,15467262 0,16515738 ! biogenic amine metabolic process GO:0006576 52 51 0,000 0,15751926 0,16809959 ! positive regulation of immune response GO:0050778 51 51 0,000 0,15751926 0,16800231 ! rRNA metabolic process GO:0016072 51 51 0,000 0,15751926 0,16790514 GO:0006364|rRNA processing, ! protein-DNA complex assembly GO:0065004 51 51 0,000 0,15751926 0,16780809 ! protein maturation GO:0051604 51 51 0,000 0,15751926 0,16771115 ! cholesterol metabolic process GO:0008203 52 52 0,000 0,16035672 0,17063363 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 52 52 0,000 0,16035672 0,17053517 ! cell fate commitment GO:0045165 52 52 0,000 0,16035672 0,17043682 ! regulation of GTPase activity GO:0043087 53 52 0,000 0,16035672 0,17033858 ! regulation of body fluid levels GO:0050878 55 52 0,000 0,16035672 0,17024046 ! carbohydrate biosynthetic process GO:0016051 53 53 0,000 0,16318505 0,17314338 ! carbohydrate catabolic process GO:0016052 53 53 0,000 0,16318505 0,17304375 ! protein amino acid dephosphorylation GO:0006470 55 54 0,000 0,16600426 0,17593206 ! response to virus GO:0009615 54 54 0,000 0,16600426 0,17583095 ! hormone metabolic process GO:0042445 55 54 0,000 0,16600426 0,17572995 ! negative regulation of multicellular organismal process GO:0051241 55 54 0,000 0,16600426 0,17562907 ! nucleosome organization GO:0034728 55 55 0,000 0,16881438 0,17849966 ! microtubule cytoskeleton organization GO:0000226 55 55 0,000 0,16881438 0,17839731 ! in utero embryonic development GO:0001701 55 55 0,000 0,16881438 0,17829507 ! reproductive developmental process GO:0003006 56 56 0,000 0,17161545 0,18114964 ! regulation of nervous system development GO:0051960 57 56 0,000 0,17161545 0,18104595 ! innate immune response GO:0045087 58 58 0,000 0,17719051 0,18682043 ! dephosphorylation GO:0016311 60 59 0,000 0,17996457 0,18963677 ! carboxylic acid transport GO:0046942 59 59 0,000 0,17996457 0,1895284 GO:0015849|organic acid transport, ! regulation of cell development GO:0060284 60 59 0,000 0,17996457 0,18942016 ! sterol metabolic process GO:0016125 59 59 0,000 0,17996457 0,18931205 ! cellular aromatic compound metabolic process GO:0006725 60 59 0,000 0,17996457 0,18920405 ! immune effector process GO:0002252 59 59 0,000 0,17996457 0,18909618 ! negative regulation of cellular protein metabolic process GO:0032269 60 60 0,000 0,18272968 0,19189219 ! protein polymerization GO:0051258 65 60 0,000 0,18272968 0,19178292 ! cellular respiration GO:0045333 62 61 0,000 0,18548587 0,19456486 ! proteasomal protein catabolic process GO:0010498 62 61 0,000 0,18548587 0,19445419 GO:0043161|proteasomal ubiquitin-dependent protein catabolic process, ! carboxylic acid catabolic process GO:0046395 63 61 0,000 0,18548587 0,19434364 GO:0016054|organic acid catabolic process, ! lipid transport GO:0006869 62 62 0,000 0,18823317 0,19711007 ! morphogenesis of an epithelium GO:0002009 63 62 0,000 0,18823317 0,19699814 GO:0060429|epithelium development, ! di-, tri-valent inorganic cation transport GO:0015674 63 62 0,000 0,18823317 0,19688634 ! regulation of secretion GO:0051046 65 63 0,000 0,1909716 0,19963736 ! negative regulation of cellular component organization GO:0051129 65 63 0,000 0,1909716 0,19952419 ! glucose metabolic process GO:0006006 63 63 0,000 0,1909716 0,19941114 ! glycerolipid metabolic process GO:0046486 65 64 0,000 0,1937012 0,20214683 ! regulation of response to external stimulus GO:0032101 65 64 0,000 0,1937012 0,20203243 ! angiogenesis GO:0001525 65 64 0,000 0,1937012 0,20191816 ! regulation of cytoskeleton organization GO:0051493 66 64 0,000 0,1937012 0,20180402 ! anion transport GO:0006820 65 65 0,000 0,19642198 0,204523 ! positive regulation of cellular component organization GO:0051130 65 65 0,000 0,19642198 0,20440752 ! regulation of hormone levels GO:0010817 66 65 0,000 0,19642198 0,20429216 ! protein amino acid glycosylation GO:0006486 66 66 0,000 0,19913399 0,20699601 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! DNA packaging GO:0006323 66 66 0,000 0,19913399 0,20687933 ! polysaccharide metabolic process GO:0005976 69 66 0,000 0,19913399 0,20676278 ! negative regulation of protein metabolic process GO:0051248 66 66 0,000 0,19913399 0,20664636 ! Golgi vesicle transport GO:0048193 67 67 0,000 0,20183723 0,20933372 ! muscle contraction GO:0006936 67 67 0,000 0,20183723 0,20921598 ! negative regulation of cell differentiation GO:0045596 68 67 0,000 0,20183723 0,20909838 ! Ras protein signal transduction GO:0007265 69 67 0,000 0,20183723 0,20898091 ! chromatin assembly or disassembly GO:0006333 68 68 0,000 0,20453175 0,21165189 ! regulation of cell size GO:0008361 68 68 0,000 0,20453175 0,21153312 ! regulation of translation GO:0006417 69 69 0,000 0,20721756 0,21419067 ! sensory perception of sound GO:0007605 71 69 0,000 0,20721756 0,21407061 GO:0050954|sensory perception of mechanical stimulus, ! regionalization GO:0003002 70 69 0,000 0,20721756 0,21395068 ! response to nutrient levels GO:0031667 69 69 0,000 0,20721756 0,21383089 ! regulation of mitotic cell cycle GO:0007346 72 69 0,000 0,20721756 0,21371123 ! positive regulation of transport GO:0051050 71 70 0,000 0,2098947 0,21635119 ! growth GO:0040007 70 70 0,000 0,2098947 0,21623026 ! carboxylic acid biosynthetic process GO:0046394 70 70 0,000 0,2098947 0,21610946 GO:0016053|organic acid biosynthetic process, ! translational elongation GO:0006414 71 71 0,000 0,21256319 0,21873477 ! oxidative phosphorylation GO:0006119 71 71 0,000 0,21256319 0,2186127 ! calcium ion homeostasis GO:0055074 71 71 0,000 0,21256319 0,21849078 GO:0006874|cellular calcium ion homeostasis, ! ribosome biogenesis GO:0042254 71 71 0,000 0,21256319 0,21836899 ! negative regulation of signal transduction GO:0009968 71 71 0,000 0,21256319 0,21824733 ! secretion by cell GO:0032940 75 72 0,000 0,21522306 0,22085529 ! muscle system process GO:0003012 72 72 0,000 0,21522306 0,22073239 ! sensory organ development GO:0007423 72 72 0,000 0,21522306 0,22060962 ! response to extracellular stimulus GO:0009991 72 72 0,000 0,21522306 0,22048699 ! regulation of cytokine production GO:0001817 72 72 0,000 0,21522306 0,2203645 ! electron transport chain GO:0022900 75 74 0,000 0,22051704 0,22565958 ! coenzyme metabolic process GO:0006732 75 74 0,000 0,22051704 0,22553435 ! negative regulation of cell communication GO:0010648 76 76 0,000 0,22577685 0,23078576 ! cellular metal ion homeostasis GO:0006875 77 77 0,000 0,228394 0,23333157 ! microtubule-based movement GO:0007018 82 78 0,000 0,2310027 0,23586591 ! metal ion homeostasis GO:0055065 78 78 0,000 0,2310027 0,23573531 ! regulation of immune response GO:0050776 78 78 0,000 0,2310027 0,23560485 ! glycoprotein biosynthetic process GO:0009101 80 80 0,000 0,2361948 0,24076715 ! tube development GO:0035295 83 81 0,000 0,23877826 0,24326607 ! lymphocyte activation GO:0046649 82 81 0,000 0,23877826 0,24313167 ! lipid catabolic process GO:0016042 82 81 0,000 0,23877826 0,24299742 ! ncRNA processing GO:0034470 83 83 0,000 0,24392012 0,24809315 ! blood vessel morphogenesis GO:0048514 84 83 0,000 0,24392012 0,24795631 ! nitrogen compound biosynthetic process GO:0044271 86 85 0,000 0,24902875 0,25300992 ! positive regulation of cell differentiation GO:0045597 87 85 0,000 0,24902875 0,25287052 ! positive regulation of response to stimulus GO:0048584 86 85 0,000 0,24902875 0,25273127 ! organophosphate metabolic process GO:0019637 87 86 0,000 0,25157067 0,25517047 GO:0006644|phospholipid metabolic process, ! hexose metabolic process GO:0019318 87 86 0,000 0,25157067 0,25503012 ! male gamete generation GO:0048232 90 88 0,000 0,25662984 0,26001583 GO:0007283|spermatogenesis, ! chemotaxis GO:0006935 90 89 0,000 0,25914714 0,26242208 GO:0042330|taxis, ! cellular di-, tri-valent inorganic cation homeostasis GO:0030005 89 89 0,000 0,25914714 0,26227797 ! regulation of Ras protein signal transduction GO:0046578 90 90 0,000 0,26165629 0,26467209 ! di-, tri-valent inorganic cation homeostasis GO:0055066 91 91 0,000 0,26415731 0,26705536 ! DNA replication GO:0006260 91 91 0,000 0,26415731 0,26690895 ! visual perception GO:0007601 93 92 0,000 0,26665022 0,2692802 GO:0050953|sensory perception of light stimulus, ! energy derivation by oxidation of organic compounds GO:0015980 94 92 0,000 0,26665022 0,26913273 ! positive regulation of immune system process GO:0002684 92 92 0,000 0,26665022 0,26898542 ! tissue morphogenesis GO:0048729 94 93 0,000 0,26913505 0,27134349 ! regulation of response to stress GO:0080134 97 94 0,000 0,27161183 0,27369087 ! blood vessel development GO:0001568 95 94 0,000 0,27161183 0,27354131 ! pattern specification process GO:0007389 96 94 0,000 0,27161183 0,27339192 ! epidermis development GO:0008544 94 94 0,000 0,27161183 0,27324269 ! cofactor metabolic process GO:0051186 95 94 0,000 0,27161183 0,27309362 ! regulation of cell growth GO:0001558 97 96 0,000 0,27654132 0,2778984 ! vasculature development GO:0001944 97 96 0,000 0,27654132 0,27774695 ! posttranscriptional regulation of gene expression GO:0010608 98 98 0,000 0,2814389 0,28251192 ! glycoprotein metabolic process GO:0009100 99 98 0,000 0,2814389 0,28235813 ! blood circulation GO:0008015 99 98 0,000 0,2814389 0,28220451 GO:0003013|circulatory system process, ! regulation of system process GO:0044057 98 98 0,000 0,2814389 0,28205105 ! anti-apoptosis GO:0006916 100 99 0,000 0,28387577 0,28433861 ! ectoderm development GO:0007398 99 99 0,000 0,28387577 0,28418417 ! response to other organism GO:0051707 101 100 0,000 0,28630475 0,28646018 ! hemopoiesis GO:0030097 104 100 0,000 0,28630475 0,28630475