pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6641-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! G1/S transition of mitotic cell cycle GO:0000082 115 46 6,000 4,127E-09 9,929E-06 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 7,000 8,69E-09 1,045E-05 ! regulation of ligase activity GO:0051340 142 84 7,000 1,421E-08 1,139E-05 ! interphase of mitotic cell cycle GO:0051329 209 95 7,000 3,774E-08 2,27E-05 ! interphase GO:0051325 213 98 7,000 4,822E-08 2,32E-05 ! induction of positive chemotaxis GO:0050930 15 9 3,000 8,775E-08 3,519E-05 ! negative regulation of phosphorylation GO:0042326 47 24 4,000 1,417E-07 4,87E-05 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 4,000 2,174E-07 6,539E-05 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of positive chemotaxis GO:0050926 19 12 3,000 3,405E-07 9,104E-05 GO:0050927|positive regulation of positive chemotaxis, ! negative regulation of ligase activity GO:0051352 112 68 5,000 1,528E-06 3,677E-04 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 3,000 1,604E-06 3,509E-04 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 5,000 1,667E-06 3,342E-04 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 5,000 2,145E-06 3,969E-04 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 5,000 2,145E-06 3,685E-04 ! positive regulation of ligase activity GO:0051351 124 77 5,000 3,185E-06 5,109E-04 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 3,000 3,227E-06 4,852E-04 ! induction of apoptosis by intracellular signals GO:0008629 93 45 4,000 3,729E-06 5,277E-04 ! positive regulation of locomotion GO:0040017 39 21 3,000 3,97E-06 5,306E-04 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 2,000 4,79E-06 6,066E-04 ! embryonic heart tube development GO:0035050 10 7 2,000 4,79E-06 5,763E-04 ! regulation of chemotaxis GO:0050920 40 22 3,000 4,832E-06 5,536E-04 ! regulation of behavior GO:0050795 43 24 3,000 6,962E-06 7,614E-04 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 2,000 7,635E-06 7,987E-04 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 2,000 7,635E-06 7,654E-04 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 2,000 7,635E-06 7,348E-04 ! regulation of cell cycle process GO:0010564 149 90 5,000 7,911E-06 7,321E-04 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 3,000 8,255E-06 7,356E-04 ! insulin receptor signaling pathway GO:0008286 64 26 3,000 9,716E-06 8,349E-04 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 2,000 1,141E-05 9,465E-04 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 4,000 1,215E-05 9,745E-04 ! protein amino acid autophosphorylation GO:0046777 141 60 4,000 1,565E-05 1,215E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 2,000 1,624E-05 1,221E-03 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 2,000 1,624E-05 1,184E-03 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 2,000 2,224E-05 1,574E-03 ! chondrocyte differentiation GO:0002062 24 11 2,000 2,224E-05 1,529E-03 ! negative regulation of glucose import GO:0046325 17 11 2,000 2,224E-05 1,486E-03 GO:0010829|negative regulation of glucose transport, ! negative regulation of protein kinase activity GO:0006469 130 67 4,000 2,688E-05 1,748E-03 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 4,000 2,688E-05 1,702E-03 ! negative regulation of kinase activity GO:0033673 131 68 4,000 2,889E-05 1,782E-03 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 4,000 2,889E-05 1,738E-03 ! positive regulation of cellular catabolic process GO:0031331 31 12 2,000 2,954E-05 1,733E-03 ! regulation of B cell proliferation GO:0030888 20 12 2,000 2,954E-05 1,692E-03 ! negative regulation of mast cell proliferation GO:0070667 23 12 2,000 2,954E-05 1,653E-03 GO:0042130|negative regulation of T cell proliferation, ! negative regulation of transferase activity GO:0051348 140 72 4,000 3,813E-05 2,085E-03 ! regulation of monooxygenase activity GO:0032768 33 13 2,000 3,825E-05 2,045E-03 ! cellular response to insulin stimulus GO:0032869 82 37 3,000 4,105E-05 2,147E-03 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 2,000 4,85E-05 2,483E-03 ! regulation of the force of heart contraction GO:0002026 26 15 2,000 6,039E-05 3,027E-03 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 2,000 6,039E-05 2,965E-03 ! embryonic forelimb morphogenesis GO:0035115 28 16 2,000 7,404E-05 3,563E-03 ! negative regulation of leukocyte proliferation GO:0070664 31 16 2,000 7,404E-05 3,493E-03 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of response to external stimulus GO:0032103 77 43 3,000 7,486E-05 3,464E-03 ! regulation of survival gene product expression GO:0045884 33 17 2,000 8,957E-05 4,066E-03 ! neutrophil chemotaxis GO:0030593 27 17 2,000 8,957E-05 3,991E-03 ! regulation of gene-specific transcription GO:0032583 96 46 3,000 9,78E-05 4,278E-03 ! response to insulin stimulus GO:0032868 95 46 3,000 9,78E-05 4,202E-03 ! peptidyl-serine phosphorylation GO:0018105 38 18 2,000 1,071E-04 4,519E-03 ! positive regulation of cell cycle GO:0045787 89 48 3,000 1,157E-04 4,798E-03 ! regulation of mast cell proliferation GO:0070666 81 48 3,000 1,157E-04 4,717E-03 ! forelimb morphogenesis GO:0035136 32 19 2,000 1,267E-04 5,079E-03 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 4,000 1,297E-04 5,116E-03 GO:0010498|proteasomal protein catabolic process, ! regulation of leukocyte proliferation GO:0070663 88 51 3,000 1,468E-04 5,695E-03 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 2,000 1,484E-04 5,669E-03 ! apoptotic mitochondrial changes GO:0008637 41 20 2,000 1,484E-04 5,58E-03 ! peptidyl-serine modification GO:0018209 43 20 2,000 1,484E-04 5,495E-03 ! regulation of glucose import GO:0046324 29 20 2,000 1,484E-04 5,411E-03 GO:0010827|regulation of glucose transport, ! negative regulation of T cell activation GO:0050868 40 20 2,000 1,484E-04 5,331E-03 ! regulation of muscle contraction GO:0006937 81 52 3,000 1,584E-04 5,603E-03 ! cartilage development GO:0051216 90 52 3,000 1,584E-04 5,522E-03 ! response to UV GO:0009411 104 53 3,000 1,706E-04 5,863E-03 ! inactivation of MAPK activity GO:0000188 39 21 2,000 1,725E-04 5,846E-03 ! positive regulation of inflammatory response GO:0050729 35 21 2,000 1,725E-04 5,765E-03 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 2,000 1,99E-04 6,559E-03 ! apoptotic nuclear changes GO:0030262 32 22 2,000 1,99E-04 6,47E-03 ! positive regulation of intracellular transport GO:0032388 37 22 2,000 1,99E-04 6,384E-03 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 2,000 1,99E-04 6,3E-03 ! positive regulation of cell migration GO:0030335 126 57 3,000 2,264E-04 7,075E-03 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 2,000 2,28E-04 7,032E-03 ! regulation of cellular catabolic process GO:0031329 52 24 2,000 2,595E-04 7,905E-03 ! regulation of oxidoreductase activity GO:0051341 46 24 2,000 2,595E-04 7,806E-03 ! negative regulation of bone resorption GO:0045779 10 5 1,000 2,673E-04 7,939E-03 ! tongue development GO:0043586 8 5 1,000 2,673E-04 7,842E-03 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 1,000 2,673E-04 7,747E-03 ! positive regulation of glycolysis GO:0045821 14 5 1,000 2,673E-04 7,655E-03 ! anagen GO:0042640 6 5 1,000 2,673E-04 7,565E-03 ! positive regulation of viral genome replication GO:0045070 9 5 1,000 2,673E-04 7,477E-03 ! regulation of retroviral genome replication GO:0045091 7 5 1,000 2,673E-04 7,391E-03 ! regulation of cardiac muscle contraction GO:0055117 5 5 1,000 2,673E-04 7,307E-03 ! response to food GO:0032094 6 5 1,000 2,673E-04 7,225E-03 ! positive regulation of transporter activity GO:0032411 8 5 1,000 2,673E-04 7,145E-03 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 2,673E-04 7,066E-03 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 1,000 2,673E-04 6,99E-03 ! early endosome to late endosome transport GO:0045022 12 5 1,000 2,673E-04 6,914E-03 ! meiotic chromosome segregation GO:0045132 7 5 1,000 2,673E-04 6,841E-03 ! regulation of muscle cell apoptosis GO:0010660 8 5 1,000 2,673E-04 6,769E-03 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 1,000 2,673E-04 6,698E-03 ! stem cell division GO:0017145 11 5 1,000 2,673E-04 6,629E-03 GO:0048103|somatic stem cell division, ! regulation of heart contraction GO:0008016 110 60 3,000 2,762E-04 6,78E-03 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 2,000 2,938E-04 7,14E-03 ! vasculogenesis GO:0001570 46 25 2,000 2,938E-04 7,069E-03 ! response to peptide hormone stimulus GO:0043434 122 61 3,000 2,943E-04 7,012E-03 ! regulation of mitosis GO:0007088 105 63 3,000 3,333E-04 7,861E-03 GO:0051783|regulation of nuclear division, ! positive regulation of cell motion GO:0051272 146 64 3,000 3,541E-04 8,27E-03 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 2,000 3,708E-04 8,578E-03 ! negative regulation of lymphocyte activation GO:0051250 53 27 2,000 3,708E-04 8,497E-03 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 1,000 3,995E-04 9,068E-03 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 1,000 3,995E-04 8,984E-03 ! male sex determination GO:0030238 15 6 1,000 3,995E-04 8,9E-03 ! establishment of spindle localization GO:0051293 12 6 1,000 3,995E-04 8,819E-03 GO:0051653|spindle localization, ! hair follicle maturation GO:0048820 7 6 1,000 3,995E-04 8,739E-03 ! negative regulation of B cell activation GO:0050869 13 6 1,000 3,995E-04 8,66E-03 ! negative regulation of protein modification process GO:0031400 60 28 2,000 4,137E-04 8,887E-03 ! lung development GO:0030324 144 67 3,000 4,22E-04 8,985E-03 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 3,000 4,22E-04 8,906E-03 ! cellular response to extracellular stimulus GO:0031668 48 29 2,000 4,597E-04 9,618E-03 ! negative regulation of cell size GO:0045792 134 69 3,000 4,721E-04 9,792E-03 ! respiratory tube development GO:0030323 150 70 3,000 4,987E-04 0,01025547 ! negative regulation of leukocyte activation GO:0002695 56 30 2,000 5,088E-04 0,0103748 ! regulation of B cell activation GO:0050864 50 30 2,000 5,088E-04 0,01028761 ! respiratory system development GO:0060541 153 72 3,000 5,551E-04 0,01112922 ! prostate gland development GO:0030850 13 7 1,000 5,574E-04 0,01108376 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 5,574E-04 0,01099291 ! N-terminal protein amino acid acetylation GO:0006474 13 7 1,000 5,574E-04 0,01090354 ! mRNA stabilization GO:0048255 18 7 1,000 5,574E-04 0,0108156 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 1,000 5,574E-04 0,01072908 ! positive regulation of monooxygenase activity GO:0032770 12 7 1,000 5,574E-04 0,01064393 ! regulation of meiosis GO:0040020 12 7 1,000 5,574E-04 0,01056012 GO:0051445|regulation of meiotic cell cycle, ! regulation of respiratory burst GO:0060263 11 7 1,000 5,574E-04 0,01047762 ! anaphase GO:0051322 17 7 1,000 5,574E-04 0,01039639 GO:0000090|mitotic anaphase, ! negative regulation of transcription regulator activity GO:0090048 58 31 2,000 5,612E-04 0,01038636 GO:0043433|negative regulation of transcription factor activity, ! regulation of transcription factor activity GO:0051090 126 74 3,000 6,158E-04 0,01131046 GO:0090046|regulation of transcription regulator activity, ! negative regulation of MAP kinase activity GO:0043407 69 32 2,000 6,169E-04 0,01124416 ! positive regulation of catabolic process GO:0009896 64 32 2,000 6,169E-04 0,01115962 ! positive regulation of gene-specific transcription GO:0043193 65 33 2,000 6,76E-04 0,01213755 ! leukocyte chemotaxis GO:0030595 50 33 2,000 6,76E-04 0,01204765 GO:0060326|cell chemotaxis, ! regulation of catabolic process GO:0009894 161 76 3,000 6,811E-04 0,01205025 ! T-helper 1 type immune response GO:0042088 12 8 1,000 7,407E-04 0,01300771 ! L-phenylalanine metabolic process GO:0006558 11 8 1,000 7,407E-04 0,01291345 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 12 8 1,000 7,407E-04 0,01282055 ! positive regulation of endothelial cell migration GO:0010595 19 8 1,000 7,407E-04 0,01272898 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 1,000 7,407E-04 0,0126387 ! regulation of vascular permeability GO:0043114 12 8 1,000 7,407E-04 0,01254969 ! cardiac muscle cell differentiation GO:0055007 27 8 1,000 7,407E-04 0,01246193 ! cardiac muscle cell development GO:0055013 13 8 1,000 7,407E-04 0,01237539 ! DNA topological change GO:0006265 12 8 1,000 7,407E-04 0,01229005 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 1,000 7,407E-04 0,01220587 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 1,000 7,407E-04 0,01212283 ! positive regulation of phosphorylation GO:0042327 129 79 3,000 7,881E-04 0,01281212 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 3,000 8,657E-04 0,01397878 GO:0045937|positive regulation of phosphate metabolic process, ! androgen receptor signaling pathway GO:0030521 74 36 2,000 8,746E-04 0,01402808 ! negative regulation of cell activation GO:0050866 65 36 2,000 8,746E-04 0,01393518 ! cellular response to hormone stimulus GO:0032870 167 82 3,000 9,064E-04 0,01434771 ! negative regulation of DNA binding GO:0043392 68 37 2,000 9,481E-04 0,01490956 ! regulation of protein stability GO:0031647 73 37 2,000 9,481E-04 0,01481275 ! glycogen metabolic process GO:0005977 61 37 2,000 9,481E-04 0,01471718 ! regulation of developmental growth GO:0048638 15 9 1,000 9,49E-04 0,01463701 ! autophagic vacuole formation GO:0000045 15 9 1,000 9,49E-04 0,01454378 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 9,49E-04 0,01445173 ! regulation of glycolysis GO:0006110 21 9 1,000 9,49E-04 0,01436084 ! microtubule bundle formation GO:0001578 21 9 1,000 9,49E-04 0,01427108 ! receptor clustering GO:0043113 18 9 1,000 9,49E-04 0,01418244 ! motor axon guidance GO:0008045 16 9 1,000 9,49E-04 0,01409489 ! protein heterooligomerization GO:0051291 16 9 1,000 9,49E-04 0,01400842 ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 1,000 9,49E-04 0,01392301 ! negative regulation of transport GO:0051051 153 84 3,000 9,919E-04 0,01446393 ! nucleus organization GO:0006997 67 38 2,000 1,025E-03 0,01486306 ! glucan metabolic process GO:0044042 62 38 2,000 1,025E-03 0,01477406 GO:0006073|cellular glucan metabolic process, ! regulation of DNA binding GO:0051101 155 88 3,000 1,18E-03 0,01689409 ! gland development GO:0048732 206 88 3,000 1,18E-03 0,01679413 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 1,182E-03 0,01673206 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 1,000 1,182E-03 0,01663421 ! lung alveolus development GO:0048286 26 10 1,000 1,182E-03 0,0165375 ! negative regulation of striated muscle development GO:0045843 19 10 1,000 1,182E-03 0,01644191 ! positive regulation of survival gene product expression GO:0045885 23 10 1,000 1,182E-03 0,01634742 ! glucan biosynthetic process GO:0009250 14 10 1,000 1,182E-03 0,016254 GO:0005978|glycogen biosynthetic process, ! regulation of sodium ion transport GO:0002028 21 10 1,000 1,182E-03 0,01616165 ! macroautophagy GO:0016236 17 10 1,000 1,182E-03 0,01607034 ! regulation of bone resorption GO:0045124 25 10 1,000 1,182E-03 0,01598006 ! DNA ligation GO:0006266 19 10 1,000 1,182E-03 0,01589078 ! positive regulation of leukocyte migration GO:0002687 25 10 1,000 1,182E-03 0,0158025 ! positive regulation of viral reproduction GO:0048524 18 10 1,000 1,182E-03 0,0157152 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 1,000 1,182E-03 0,01562885 GO:0043470|regulation of carbohydrate catabolic process, ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 1,000 1,182E-03 0,01554345 ! localization within membrane GO:0051668 20 10 1,000 1,182E-03 0,01545897 ! negative regulation of binding GO:0051100 72 40 2,000 1,192E-03 0,01550083 ! regulation of T cell proliferation GO:0042129 71 41 2,000 1,281E-03 0,01657142 ! regulation of T cell differentiation GO:0045580 70 41 2,000 1,281E-03 0,0164828 ! regulation of intracellular protein transport GO:0033157 80 42 2,000 1,374E-03 0,01758917 ! neuron migration GO:0001764 79 42 2,000 1,374E-03 0,01749611 ! negative regulation of muscle development GO:0048635 20 11 1,000 1,44E-03 0,01823505 ! thyroid gland development GO:0030878 26 11 1,000 1,44E-03 0,01813958 ! blood vessel remodeling GO:0001974 29 11 1,000 1,44E-03 0,01804511 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 1,000 1,44E-03 0,01795161 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 1,000 1,44E-03 0,01785907 ! peptide or protein amino-terminal blocking GO:0018409 21 11 1,000 1,44E-03 0,01776749 ! adult heart development GO:0007512 14 11 1,000 1,44E-03 0,01767684 ! DNA methylation GO:0006306 19 11 1,000 1,44E-03 0,01758711 GO:0006305|DNA alkylation, ! regulation of leukocyte migration GO:0002685 26 11 1,000 1,44E-03 0,01749828 ! positive regulation of neuron differentiation GO:0045666 19 11 1,000 1,44E-03 0,01741035 ! cardiac cell differentiation GO:0035051 31 11 1,000 1,44E-03 0,0173233 ! regulation of embryonic development GO:0045995 27 11 1,000 1,44E-03 0,01723712 ! positive regulation of MAP kinase activity GO:0043406 160 93 3,000 1,448E-03 0,01724241 ! energy reserve metabolic process GO:0006112 74 43 2,000 1,472E-03 0,01744464 ! regulation of epithelial cell proliferation GO:0050678 111 43 2,000 1,472E-03 0,01735913 ! leukocyte migration GO:0050900 68 45 2,000 1,68E-03 0,01971198 ! cell growth GO:0016049 84 45 2,000 1,68E-03 0,0196163 ! virus-host interaction GO:0019048 29 12 1,000 1,722E-03 0,02001632 ! cartilage condensation GO:0001502 20 12 1,000 1,722E-03 0,01992009 ! dopamine receptor signaling pathway GO:0007212 28 12 1,000 1,722E-03 0,01982478 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 1,000 1,722E-03 0,01973037 ! tyrosine metabolic process GO:0006570 16 12 1,000 1,722E-03 0,01963687 ! histone acetylation GO:0016573 26 12 1,000 1,722E-03 0,01954424 ! peptidyl-lysine modification GO:0018205 21 12 1,000 1,722E-03 0,01945248 ! T cell homeostasis GO:0043029 25 12 1,000 1,722E-03 0,01936158 ! aromatic amino acid family catabolic process GO:0009074 18 12 1,000 1,722E-03 0,01927153 ! spleen development GO:0048536 22 12 1,000 1,722E-03 0,01918231 ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 1,000 1,722E-03 0,01909391 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 2,000 1,79E-03 0,01975444 ! positive regulation of protein transport GO:0051222 72 46 2,000 1,79E-03 0,01966424 ! cell cycle arrest GO:0007050 213 100 3,000 1,89E-03 0,02067258 ! positive regulation of defense response GO:0031349 76 47 2,000 1,905E-03 0,02073586 ! regulation of inflammatory response GO:0050727 75 48 2,000 2,024E-03 0,02193505 ! regulation of lymphocyte differentiation GO:0045619 81 48 2,000 2,024E-03 0,02183668 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 1,000 2,028E-03 0,02178565 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of mRNA stability GO:0043488 31 13 1,000 2,028E-03 0,02168883 ! cytoplasmic sequestering of protein GO:0051220 24 13 1,000 2,028E-03 0,02159286 ! induction of apoptosis by extracellular signals GO:0008624 89 49 2,000 2,148E-03 0,02276422 ! negative regulation of immune system process GO:0002683 95 50 2,000 2,276E-03 0,02401957 ! N-terminal protein amino acid modification GO:0031365 27 14 1,000 2,358E-03 0,02477672 ! actin cytoskeleton reorganization GO:0031532 33 14 1,000 2,358E-03 0,024669 ! regulation of RNA stability GO:0043487 32 14 1,000 2,358E-03 0,02456221 ! positive regulation of growth GO:0045927 90 52 2,000 2,547E-03 0,02641484 ! negative regulation of bone remodeling GO:0046851 33 15 1,000 2,712E-03 0,0280018 ! regulation of transmembrane transporter activity GO:0022898 27 15 1,000 2,712E-03 0,02788213 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! positive regulation of oxidoreductase activity GO:0051353 22 15 1,000 2,712E-03 0,02776348 ! lymphocyte homeostasis GO:0002260 30 15 1,000 2,712E-03 0,02764584 ! positive regulation of calcium ion transport GO:0051928 19 15 1,000 2,712E-03 0,02752919 ! cellular polysaccharide metabolic process GO:0044264 86 55 2,000 2,989E-03 0,03022041 ! regulation of protein catabolic process GO:0042176 116 55 2,000 2,989E-03 0,03009396 ! heart morphogenesis GO:0003007 97 55 2,000 2,989E-03 0,02996857 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 3,089E-03 0,03083414 ! positive regulation of ion transport GO:0043270 21 16 1,000 3,089E-03 0,03070673 ! negative regulation of microtubule depolymerization GO:0007026 46 16 1,000 3,089E-03 0,03058037 GO:0031114|regulation of microtubule depolymerization, ! positive regulation of protein import into nucleus GO:0042307 30 16 1,000 3,089E-03 0,03045504 ! negative regulation of tissue remodeling GO:0034104 36 16 1,000 3,089E-03 0,03033073 ! regulation of intracellular transport GO:0032386 101 57 2,000 3,309E-03 0,03236228 ! negative regulation of cell cycle process GO:0010948 32 17 1,000 3,488E-03 0,03398016 ! signal complex assembly GO:0007172 41 17 1,000 3,488E-03 0,03384314 ! heart looping GO:0001947 30 17 1,000 3,488E-03 0,03370723 ! regulation of viral genome replication GO:0045069 28 17 1,000 3,488E-03 0,0335724 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 1,000 3,488E-03 0,03343864 ! cardiac muscle tissue development GO:0048738 31 17 1,000 3,488E-03 0,03330595 ! regulation of striated muscle contraction GO:0006942 21 17 1,000 3,488E-03 0,03317431 ! negative regulation of protein catabolic process GO:0042177 40 17 1,000 3,488E-03 0,0330437 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 1,000 3,488E-03 0,03291412 ! negative regulation of homeostatic process GO:0032845 33 17 1,000 3,488E-03 0,03278555 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 1,000 3,488E-03 0,03265798 ! negative regulation of response to stimulus GO:0048585 100 60 2,000 3,826E-03 0,03567951 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 3,911E-03 0,03633219 ! positive regulation of proteolysis GO:0045862 31 18 1,000 3,911E-03 0,03619245 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 1,000 3,911E-03 0,03605378 ! aromatic compound catabolic process GO:0019439 27 18 1,000 3,911E-03 0,03591617 ! lipid phosphorylation GO:0046834 35 19 1,000 4,356E-03 0,03985265 ! neuromuscular junction development GO:0007528 34 19 1,000 4,356E-03 0,0397017 ! regulation of endothelial cell migration GO:0010594 44 19 1,000 4,356E-03 0,03955188 ! steroid hormone receptor signaling pathway GO:0030518 129 63 2,000 4,39E-03 0,03970545 ! embryonic limb morphogenesis GO:0030326 125 65 2,000 4,792E-03 0,04318198 GO:0035113|embryonic appendage morphogenesis, ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 1,000 4,824E-03 0,04330652 ! protein amino acid acetylation GO:0006473 39 20 1,000 4,824E-03 0,04314553 ! regulation of carbohydrate metabolic process GO:0006109 38 20 1,000 4,824E-03 0,04298573 GO:0010675|regulation of cellular carbohydrate metabolic process, ! cellular response to starvation GO:0009267 33 20 1,000 4,824E-03 0,04282712 ! negative regulation of cell growth GO:0030308 132 67 2,000 5,216E-03 0,0461376 ! chromosome segregation GO:0007059 113 67 2,000 5,216E-03 0,0459686 ! hindlimb morphogenesis GO:0035137 43 21 1,000 5,313E-03 0,0466575 ! cell structure disassembly during apoptosis GO:0006921 30 21 1,000 5,313E-03 0,04648784 ! DNA modification GO:0006304 34 21 1,000 5,313E-03 0,0463194 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 2,000 5,436E-03 0,04721677 ! positive regulation of protein catabolic process GO:0045732 38 22 1,000 5,825E-03 0,05041256 ! cellular response to reactive oxygen species GO:0034614 31 22 1,000 5,825E-03 0,05023187 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 1,000 5,825E-03 0,05005248 GO:0060415|muscle tissue morphogenesis, ! response to glucocorticoid stimulus GO:0051384 38 22 1,000 5,825E-03 0,04987435 ! positive regulation of B cell activation GO:0050871 38 22 1,000 5,825E-03 0,04969749 ! aromatic amino acid family metabolic process GO:0009072 32 22 1,000 5,825E-03 0,04952188 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 1,000 5,825E-03 0,04934751 ! protein stabilization GO:0050821 39 22 1,000 5,825E-03 0,04917436 ! appendage morphogenesis GO:0035107 135 70 2,000 5,893E-03 0,04957387 GO:0035108|limb morphogenesis, ! appendage development GO:0048736 136 71 2,000 6,13E-03 0,05138593 GO:0060173|limb development, ! positive regulation of DNA replication GO:0045740 43 23 1,000 6,358E-03 0,05311524 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 6,358E-03 0,05293145 ! regulation of cell-matrix adhesion GO:0001952 78 23 1,000 6,358E-03 0,05274892 GO:0010810|regulation of cell-substrate adhesion, ! activation of pro-apoptotic gene products GO:0008633 47 23 1,000 6,358E-03 0,05256766 ! sex determination GO:0007530 47 23 1,000 6,358E-03 0,05238763 ! regulation of viral reproduction GO:0050792 38 23 1,000 6,358E-03 0,05220883 ! negative regulation of catabolic process GO:0009895 50 23 1,000 6,358E-03 0,05203125 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 2,000 6,372E-03 0,05196916 ! protein import into nucleus, translocation GO:0000060 46 24 1,000 6,912E-03 0,05618606 ! positive regulation of fibroblast proliferation GO:0048146 43 24 1,000 6,912E-03 0,05599688 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 1,000 6,912E-03 0,05580897 ! regulation of transmembrane transport GO:0034762 38 24 1,000 6,912E-03 0,05562232 ! response to corticosteroid stimulus GO:0031960 41 24 1,000 6,912E-03 0,05543691 ! leukocyte homeostasis GO:0001776 44 24 1,000 6,912E-03 0,05525273 ! protein tetramerization GO:0051262 52 24 1,000 6,912E-03 0,05506978 ! phosphoinositide-mediated signaling GO:0048015 131 75 2,000 7,133E-03 0,05664078 ! myelination GO:0042552 45 25 1,000 7,488E-03 0,05926244 ! receptor metabolic process GO:0043112 46 25 1,000 7,488E-03 0,05906814 ! chromosome condensation GO:0030261 45 25 1,000 7,488E-03 0,05887511 ! response to starvation GO:0042594 42 25 1,000 7,488E-03 0,05868333 ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 7,488E-03 0,0584928 ! interaction with host GO:0051701 62 25 1,000 7,488E-03 0,0583035 ! somitogenesis GO:0001756 43 25 1,000 7,488E-03 0,05811543 ! cellular response to nutrient levels GO:0031669 41 25 1,000 7,488E-03 0,05792856 ! neural tube closure GO:0001843 49 25 1,000 7,488E-03 0,05774289 GO:0060606|tube closure, ! negative regulation of organelle organization GO:0010639 161 78 2,000 7,946E-03 0,06107894 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 1,000 8,084E-03 0,06194509 ! molting cycle process GO:0022404 50 26 1,000 8,084E-03 0,06174844 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 1,000 8,084E-03 0,06155304 ! regulation of transcription factor import into nucleus GO:0042990 54 26 1,000 8,084E-03 0,06135886 ! regulation of endothelial cell proliferation GO:0001936 57 26 1,000 8,084E-03 0,06116591 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 1,000 8,084E-03 0,06097417 ! cellular response to oxidative stress GO:0034599 39 26 1,000 8,084E-03 0,06078362 ! positive regulation of nuclear division GO:0051785 40 26 1,000 8,084E-03 0,06059427 GO:0045840|positive regulation of mitosis, ! regulation of fibroblast proliferation GO:0048145 52 27 1,000 8,701E-03 0,06501692 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 1,000 8,701E-03 0,06481563 ! protein amino acid acylation GO:0043543 55 27 1,000 8,701E-03 0,06461558 ! autophagy GO:0006914 41 27 1,000 8,701E-03 0,06441676 ! primary neural tube formation GO:0014020 51 27 1,000 8,701E-03 0,06421917 ! regulation of chromosome organization GO:0033044 42 27 1,000 8,701E-03 0,06402278 ! response to hypoxia GO:0001666 171 81 2,000 8,811E-03 0,06463233 ! dendrite development GO:0016358 59 28 1,000 9,339E-03 0,06829574 ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 9,339E-03 0,06808878 ! peptidyl-tyrosine modification GO:0018212 50 28 1,000 9,339E-03 0,06788307 ! response to oxygen levels GO:0070482 176 83 2,000 9,417E-03 0,06824732 ! negative regulation of growth GO:0045926 155 84 2,000 9,729E-03 0,07029702 ! response to organic cyclic substance GO:0014070 55 29 1,000 9,997E-03 0,07201127 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 1,000 9,997E-03 0,07179631 ! mitochondrion organization GO:0007005 148 86 2,000 0,01037143 0,07426685 ! determination of left/right symmetry GO:0007368 47 30 1,000 0,01067427 0,07620861 ! positive regulation of multicellular organism growth GO:0040018 51 30 1,000 0,01067427 0,07598314 ! ensheathment of neurons GO:0007272 57 30 1,000 0,01067427 0,075759 GO:0008366|axon ensheathment, ! response to heat GO:0009408 50 30 1,000 0,01067427 0,07553618 ! regulation of protein transport GO:0051223 154 87 2,000 0,01070146 0,0755065 GO:0070201|regulation of establishment of protein localization, ! positive regulation of protein modification process GO:0031401 136 88 2,000 0,01103753 0,07764997 ! determination of bilateral symmetry GO:0009855 49 31 1,000 0,01137173 0,07976786 GO:0009799|determination of symmetry, ! cellular carbohydrate biosynthetic process GO:0034637 42 31 1,000 0,01137173 0,07953597 ! regulation of cell adhesion GO:0030155 212 89 2,000 0,01137964 0,07936064 ! ossification GO:0001503 188 90 2,000 0,01172783 0,08155247 ! bone development GO:0060348 189 91 2,000 0,0120821 0,08377388 ! spliceosome assembly GO:0000245 67 32 1,000 0,01208872 0,08357888 ! spindle organization GO:0007051 46 32 1,000 0,01208872 0,0833394 ! regulation of protein import into nucleus GO:0042306 63 32 1,000 0,01208872 0,08310129 ! muscle cell development GO:0055001 49 32 1,000 0,01208872 0,08286453 ! peripheral nervous system development GO:0007422 64 32 1,000 0,01208872 0,08262912 ! regulation of calcium ion transport GO:0051924 53 32 1,000 0,01208872 0,08239505 ! regulation of defense response GO:0031347 149 92 2,000 0,01244248 0,08456668 ! negative regulation of multicellular organismal process GO:0051241 166 93 2,000 0,01280897 0,08681237 ! negative regulation of protein transport GO:0051224 69 33 1,000 0,01282502 0,08667697 ! regulation of T cell activation GO:0050863 158 94 2,000 0,0131816 0,08883736 ! regulation of striated muscle tissue development GO:0016202 69 34 1,000 0,01358042 0,09126955 ! placenta development GO:0001890 53 34 1,000 0,01358042 0,09101532 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 1,000 0,01358042 0,0907625 ! regulation of protein localization GO:0032880 176 97 2,000 0,01433643 0,09554972 ! regulation of muscle development GO:0048634 70 35 1,000 0,01435471 0,09540725 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 1,000 0,01435471 0,09514442 ! negative regulation of cell adhesion GO:0007162 81 35 1,000 0,01435471 0,09488303 ! calcium-mediated signaling GO:0019722 62 35 1,000 0,01435471 0,09462308 ! regulation of microtubule-based process GO:0032886 78 35 1,000 0,01435471 0,09436455 ! neural tube formation GO:0001841 67 35 1,000 0,01435471 0,09410742 ! skeletal muscle tissue development GO:0007519 186 99 2,000 0,01513722 0,09896779 GO:0060538|skeletal muscle organ development, ! mitotic sister chromatid segregation GO:0000070 57 36 1,000 0,01514766 0,09876764 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 1,000 0,01514766 0,0985007 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! maintenance of protein location in cell GO:0032507 86 36 1,000 0,01514766 0,0982352 ! regulation of proteolysis GO:0030162 72 36 1,000 0,01514766 0,09797113 ! meiosis I GO:0007127 65 37 1,000 0,01595906 0,10294234 ! sister chromatid segregation GO:0000819 58 37 1,000 0,01595906 0,1026671 ! tissue remodeling GO:0048771 76 37 1,000 0,01595906 0,10239332 ! positive regulation of DNA metabolic process GO:0051054 72 38 1,000 0,0167887 0,10742984 ! regulation of metal ion transport GO:0010959 63 38 1,000 0,0167887 0,10714488 ! carbohydrate homeostasis GO:0033500 53 38 1,000 0,0167887 0,10686142 GO:0042593|glucose homeostasis, ! embryonic epithelial tube formation GO:0001838 72 38 1,000 0,0167887 0,10657947 ! positive regulation of leukocyte proliferation GO:0070665 62 38 1,000 0,0167887 0,106299 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! mammary gland development GO:0030879 86 39 1,000 0,01763638 0,11137304 ! segmentation GO:0035282 67 39 1,000 0,01763638 0,11108148 ! regulation of action potential in neuron GO:0019228 73 39 1,000 0,01763638 0,11079145 ! maintenance of protein location GO:0045185 91 40 1,000 0,01850188 0,11592583 ! cytokinesis GO:0000910 72 40 1,000 0,01850188 0,11562473 ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 0,02028553 0,12644295 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 1,000 0,02028553 0,12611622 ! negative regulation of protein complex disassembly GO:0043242 101 42 1,000 0,02028553 0,12579118 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 1,000 0,02120327 0,13114412 ! glucose transport GO:0015758 65 43 1,000 0,02120327 0,13080785 ! striated muscle cell differentiation GO:0051146 82 43 1,000 0,02120327 0,13047331 ! neural tube development GO:0021915 77 43 1,000 0,02120327 0,13014047 ! hexose transport GO:0008645 67 44 1,000 0,02213802 0,13553198 GO:0015749|monosaccharide transport, ! biopolymer methylation GO:0043414 84 44 1,000 0,02213802 0,13518799 ! developmental growth GO:0048589 82 44 1,000 0,02213802 0,13484574 ! maintenance of location in cell GO:0051651 97 44 1,000 0,02213802 0,13450522 ! polysaccharide biosynthetic process GO:0000271 70 45 1,000 0,02308957 0,13993329 ! negative regulation of cell migration GO:0030336 115 46 1,000 0,02405774 0,14543449 ! endosome transport GO:0016197 108 47 1,000 0,02504232 0,15100709 ! positive regulation of DNA binding GO:0043388 73 47 1,000 0,02504232 0,15062957 ! vascular process in circulatory system GO:0003018 80 47 1,000 0,02504232 0,15025394 ! methylation GO:0032259 90 47 1,000 0,02504232 0,14988017 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,02579637 0,15401007 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,02579637 0,15362886 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,02579637 0,15324953 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,02579637 0,15287207 ! neuron fate determination GO:0048664 7 5 0,000 0,02579637 0,15249646 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02579637 0,1521227 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,02579637 0,15175076 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,02579637 0,15138063 ! polyol transport GO:0015791 12 5 0,000 0,02579637 0,15101231 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,02579637 0,15064578 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,02579637 0,15028102 ! response to superoxide GO:0000303 10 5 0,000 0,02579637 0,14991802 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,02579637 0,14955677 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,02579637 0,14919726 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! female meiosis GO:0007143 7 5 0,000 0,02579637 0,14883947 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,02579637 0,1484834 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,02579637 0,14812902 ! cobalt ion transport GO:0006824 11 5 0,000 0,02579637 0,14777633 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,02579637 0,14742532 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,02579637 0,14707597 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,02579637 0,14672827 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,02579637 0,14638222 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,02579637 0,14603779 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,02579637 0,14569498 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,02579637 0,14535377 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,02579637 0,14501416 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,02579637 0,14467613 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02579637 0,14433967 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,02579637 0,14400478 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,02579637 0,14367144 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 0,02579637 0,14333963 ! negative chemotaxis GO:0050919 14 5 0,000 0,02579637 0,14300935 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,02579637 0,1426806 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,02579637 0,14235335 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,02579637 0,1420276 ! behavioral response to pain GO:0048266 9 5 0,000 0,02579637 0,14170333 ! clathrin coat assembly GO:0048268 14 5 0,000 0,02579637 0,14138055 ! Notch receptor processing GO:0007220 8 5 0,000 0,02579637 0,14105923 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02579637 0,14073936 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,02579637 0,14042095 ! micturition GO:0060073 9 5 0,000 0,02579637 0,14010397 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,02579637 0,13978842 ! copulation GO:0007620 9 5 0,000 0,02579637 0,13947429 ! glial cell fate commitment GO:0021781 13 5 0,000 0,02579637 0,13916157 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,02579637 0,13885025 ! spermidine metabolic process GO:0008216 7 5 0,000 0,02579637 0,13854031 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,02579637 0,13823176 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,02579637 0,13792458 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,02579637 0,13761876 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,02579637 0,13731429 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,02579637 0,13701117 ! grooming behavior GO:0007625 6 5 0,000 0,02579637 0,13670938 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,02579637 0,13640892 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,02579637 0,13610978 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02579637 0,13581195 ! response to protozoan GO:0001562 10 5 0,000 0,02579637 0,13551541 ! lymph vessel development GO:0001945 10 5 0,000 0,02579637 0,13522017 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,02579637 0,13492622 ! endochondral ossification GO:0001958 16 5 0,000 0,02579637 0,13463354 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,02579637 0,13434212 ! parathyroid gland development GO:0060017 13 5 0,000 0,02579637 0,13405197 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,02579637 0,13376306 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,02579637 0,1334754 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,02579637 0,13318897 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,02579637 0,13290377 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,02579637 0,13261979 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,02579637 0,13233701 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,02579637 0,13205545 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,02579637 0,13177507 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,02579637 0,13149589 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,02579637 0,13121789 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,02579637 0,13094105 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,02579637 0,13066539 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,02579637 0,13039088 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,02579637 0,13011753 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 0,02579637 0,12984531 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,02579637 0,12957424 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,02579637 0,12930429 ! histidine catabolic process GO:0006548 6 5 0,000 0,02579637 0,12903547 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,02579637 0,12876776 ! microvillus organization GO:0032528 7 5 0,000 0,02579637 0,12850116 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 0,02579637 0,12823566 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,02579637 0,12797126 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,02579637 0,12770794 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,02579637 0,12744571 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,02579637 0,12718455 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,02579637 0,12692446 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,02579637 0,12666543 ! polyol catabolic process GO:0046174 7 5 0,000 0,02579637 0,12640745 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,02579637 0,12615053 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,02579637 0,12589464 ! muscle cell migration GO:0014812 8 5 0,000 0,02579637 0,1256398 ! mitochondrial fission GO:0000266 8 5 0,000 0,02579637 0,12538598 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,02579637 0,12513319 ! mRNA transcription GO:0009299 9 5 0,000 0,02579637 0,12488141 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,02579637 0,12463064 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,02579637 0,12438088 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,02579637 0,12413212 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,02579637 0,12388435 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,02579637 0,12363757 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,02579637 0,12339177 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,02579637 0,12314694 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,02579637 0,12290309 ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,02579637 0,1226602 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02579637 0,12241826 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,02579637 0,12217728 ! forebrain neuron development GO:0021884 13 5 0,000 0,02579637 0,12193725 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,02579637 0,12169816 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,02579637 0,12146 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02579637 0,12122277 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,02579637 0,12098647 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,02579637 0,12075109 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02579637 0,12051662 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,02579637 0,12028306 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,02579637 0,12005041 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,02579637 0,11981865 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,02579637 0,11958778 ! basic amino acid transport GO:0015802 11 5 0,000 0,02579637 0,11935781 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,02579637 0,11912871 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,02579637 0,1189005 ! depyrimidination GO:0045008 10 5 0,000 0,02579637 0,11867315 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,02579637 0,11844668 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02579637 0,11822107 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,02579637 0,11799631 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,02579637 0,11777241 GO:0006882|cellular zinc ion homeostasis, ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,02579637 0,11754936 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02579637 0,11732715 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,02579637 0,11710577 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,02579637 0,11688524 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,02579637 0,11666553 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,02579637 0,11644664 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,02579637 0,11622858 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02579637 0,11601133 ! response to arsenic GO:0046685 10 5 0,000 0,02579637 0,11579489 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,02579637 0,11557926 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,02579637 0,11536442 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,02579637 0,11515039 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,02579637 0,11493715 ! response to cadmium ion GO:0046686 7 5 0,000 0,02579637 0,11472469 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,02579637 0,11451303 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,02579637 0,11430214 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,02579637 0,11409202 ! decidualization GO:0046697 11 5 0,000 0,02579637 0,11388268 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,02579637 0,1136741 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,02579637 0,11346629 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,02579637 0,11325923 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,02579637 0,11305293 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,02579637 0,11284738 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,02579637 0,11264258 ! neural tube patterning GO:0021532 7 5 0,000 0,02579637 0,11243851 ! embryonic cleavage GO:0040016 6 5 0,000 0,02579637 0,11223519 ! peroxisome fission GO:0016559 5 5 0,000 0,02579637 0,1120326 ! histone demethylation GO:0016577 10 5 0,000 0,02579637 0,11183074 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,02579637 0,1116296 ! mitotic recombination GO:0006312 9 5 0,000 0,02579637 0,11142919 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,02579637 0,1112295 ! metaphase plate congression GO:0051310 7 5 0,000 0,02579637 0,11103052 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02579637 0,11083225 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,02579637 0,11063469 ! enteric nervous system development GO:0048484 8 5 0,000 0,02579637 0,11043783 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,02579637 0,11024167 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,02579637 0,11004621 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,02579637 0,10985143 ! muscle cell proliferation GO:0033002 11 5 0,000 0,02579637 0,10965735 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,02579637 0,10946395 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,02579637 0,10927123 ! plasminogen activation GO:0031639 5 5 0,000 0,02579637 0,10907919 ! B cell homeostasis GO:0001782 13 5 0,000 0,02579637 0,10888782 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,02579637 0,10869713 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,02579637 0,1085071 ! metaphase GO:0051323 8 5 0,000 0,02579637 0,10831773 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,02579637 0,10812902 ! cellular response to nutrient GO:0031670 8 5 0,000 0,02579637 0,10794097 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,02579637 0,10775358 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,02579637 0,10756683 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,02579637 0,10738073 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,02579637 0,10719527 ! response to redox state GO:0051775 5 5 0,000 0,02579637 0,10701045 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,02579637 0,10682626 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,02579637 0,10664271 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,02579637 0,10645979 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,02579637 0,1062775 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02579637 0,10609583 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,02579637 0,10591478 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02579637 0,10573434 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,02579637 0,10555452 ! striatum development GO:0021756 9 5 0,000 0,02579637 0,10537531 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,02579637 0,10519671 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,02579637 0,10501871 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,02579637 0,10484132 ! glial cell migration GO:0008347 11 5 0,000 0,02579637 0,10466452 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,02579637 0,10448832 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,02579637 0,10431271 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,02579637 0,10413768 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,02579637 0,10396325 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,02579637 0,1037894 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,02579637 0,10361613 ! neuroprotection GO:0043526 6 5 0,000 0,02579637 0,10344343 ! neural plate development GO:0001840 8 5 0,000 0,02579637 0,10327131 ! regulation of sensory perception GO:0051931 7 5 0,000 0,02579637 0,10309977 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,02579637 0,10292879 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,02579637 0,10275838 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,02579637 0,10258853 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,02579637 0,10241924 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,02579637 0,10225051 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,02579637 0,10208234 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,02579637 0,10191471 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,02579637 0,10174764 ! spindle assembly GO:0051225 6 5 0,000 0,02579637 0,10158111 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,02579637 0,10141513 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,02579637 0,10124969 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,02579637 0,10108479 ! drug metabolic process GO:0017144 6 5 0,000 0,02579637 0,10092042 ! phospholipid scrambling GO:0017121 8 5 0,000 0,02579637 0,10075659 ! organ regeneration GO:0031100 7 5 0,000 0,02579637 0,10059329 ! carnitine metabolic process GO:0009437 7 5 0,000 0,02579637 0,10043052 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,02579637 0,10026827 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,02579637 0,10010655 ! cellular component disassembly GO:0022411 86 48 1,000 0,02604312 0,10090137 ! morphogenesis of embryonic epithelium GO:0016331 91 48 1,000 0,02604312 0,10073915 ! activation of caspase activity GO:0006919 84 48 1,000 0,02604312 0,10057745 ! regulation of action potential GO:0001508 95 49 1,000 0,02705995 0,10433691 ! regulation of protein complex disassembly GO:0043244 113 49 1,000 0,02705995 0,10416997 ! regulation of ion transport GO:0043269 77 49 1,000 0,02705995 0,10400357 ! response to temperature stimulus GO:0009266 76 49 1,000 0,02705995 0,10383769 ! endocrine system development GO:0035270 104 49 1,000 0,02705995 0,10367234 ! ribonucleoprotein complex assembly GO:0022618 95 49 1,000 0,02705995 0,10350752 ! histone modification GO:0016570 91 50 1,000 0,0280926 0,10728699 ! regulation of gene expression, epigenetic GO:0040029 105 50 1,000 0,0280926 0,10711697 ! positive regulation of binding GO:0051099 78 51 1,000 0,0291409 0,11093832 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 1,000 0,0291409 0,11076306 ! vesicle organization GO:0016050 107 51 1,000 0,0291409 0,11058835 ! regulation of cell shape GO:0008360 125 51 1,000 0,0291409 0,1104142 ! epithelial tube morphogenesis GO:0060562 98 51 1,000 0,0291409 0,11024059 ! regulation of angiogenesis GO:0045765 114 52 1,000 0,03020466 0,11408541 ! covalent chromatin modification GO:0016569 101 52 1,000 0,03020466 0,11390659 ! synapse organization GO:0050808 85 52 1,000 0,03020466 0,11372834 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,03087574 0,11607347 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,03087574 0,11589239 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,03087574 0,11571187 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,03087574 0,11553192 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,03087574 0,11535252 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,03087574 0,11517368 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,03087574 0,11499539 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,03087574 0,11481765 ! sleep GO:0030431 13 6 0,000 0,03087574 0,11464047 ! response to oxygen radical GO:0000305 11 6 0,000 0,03087574 0,11446383 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,03087574 0,11428773 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,03087574 0,11411217 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,03087574 0,11393715 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,03087574 0,11376267 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,03087574 0,11358872 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,03087574 0,1134153 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,03087574 0,11324241 ! forebrain regionalization GO:0021871 8 6 0,000 0,03087574 0,11307005 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,03087574 0,11289821 ! male meiosis GO:0007140 7 6 0,000 0,03087574 0,11272689 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,03087574 0,11255609 ! response to zinc ion GO:0010043 9 6 0,000 0,03087574 0,11238581 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,03087574 0,11221605 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,03087574 0,11204679 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,03087574 0,11187805 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,03087574 0,11170981 ! malate metabolic process GO:0006108 11 6 0,000 0,03087574 0,11154208 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,03087574 0,11137485 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,03087574 0,11120812 ! protein refolding GO:0042026 15 6 0,000 0,03087574 0,11104189 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,03087574 0,11087615 ! opsonization GO:0008228 8 6 0,000 0,03087574 0,11071091 ! mating behavior GO:0007617 7 6 0,000 0,03087574 0,11054616 ! neuron remodeling GO:0016322 15 6 0,000 0,03087574 0,11038191 ! erythrocyte maturation GO:0043249 7 6 0,000 0,03087574 0,11021813 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,03087574 0,11005485 ! equilibrioception GO:0050957 14 6 0,000 0,03087574 0,10989205 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,03087574 0,10972972 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,03087574 0,10956788 ! photoreceptor cell development GO:0042461 10 6 0,000 0,03087574 0,10940651 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,03087574 0,10924562 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,03087574 0,1090852 ! response to interferon-gamma GO:0034341 15 6 0,000 0,03087574 0,10892525 ! toxin metabolic process GO:0009404 11 6 0,000 0,03087574 0,10876577 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,03087574 0,10860676 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,03087574 0,10844821 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,03087574 0,10829012 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,03087574 0,10813249 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,03087574 0,10797532 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,03087574 0,10781861 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,03087574 0,10766235 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,03087574 0,10750655 ! thymic T cell selection GO:0045061 12 6 0,000 0,03087574 0,10735119 ! protein lipoylation GO:0009249 10 6 0,000 0,03087574 0,10719628 ! cysteine metabolic process GO:0006534 10 6 0,000 0,03087574 0,10704182 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,03087574 0,1068878 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,03087574 0,10673423 ! glutamate catabolic process GO:0006538 10 6 0,000 0,03087574 0,10658109 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,03087574 0,1064284 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,03087574 0,10627614 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,03087574 0,10612432 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,03087574 0,10597293 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,03087574 0,10582197 ! hyperosmotic response GO:0006972 9 6 0,000 0,03087574 0,10567144 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,03087574 0,10552134 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,03087574 0,10537166 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,03087574 0,10522241 ! urea metabolic process GO:0019627 7 6 0,000 0,03087574 0,10507358 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,03087574 0,10492517 ! neutrophil activation GO:0042119 8 6 0,000 0,03087574 0,10477718 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,03087574 0,10462961 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,03087574 0,10448245 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,03087574 0,10433571 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,03087574 0,10418937 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,03087574 0,10404345 ! neuron apoptosis GO:0051402 9 6 0,000 0,03087574 0,10389793 ! nucleoside salvage GO:0043174 9 6 0,000 0,03087574 0,10375282 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,03087574 0,10360812 ! T cell mediated immunity GO:0002456 16 6 0,000 0,03087574 0,10346382 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,03087574 0,10331992 GO:0010543|regulation of platelet activation, ! carnitine transport GO:0015879 10 6 0,000 0,03087574 0,10317642 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,03087574 0,10303332 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,03087574 0,10289061 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,03087574 0,1027483 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,03087574 0,10260638 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,03087574 0,10246486 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,03087574 0,10232372 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,03087574 0,10218297 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,03087574 0,10204261 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,03087574 0,10190264 ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,03087574 0,10176304 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,03087574 0,10162383 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,03087574 0,101485 ! neural nucleus development GO:0048857 14 6 0,000 0,03087574 0,10134655 ! response to UV-C GO:0010225 11 6 0,000 0,03087574 0,10120848 ! astrocyte development GO:0014002 15 6 0,000 0,03087574 0,10107078 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,03087574 0,10093345 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,03087574 0,1007965 ! interaction with symbiont GO:0051702 13 6 0,000 0,03087574 0,10065992 ! regulation of dendrite development GO:0050773 16 6 0,000 0,03087574 0,10052371 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,03087574 0,10038787 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,03087574 0,10025239 ! response to copper ion GO:0046688 10 6 0,000 0,03087574 0,10011728 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,03087574 0,09998253 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,03087574 0,09984815 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,03087574 0,09971412 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,03087574 0,09958046 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,03087574 0,09944715 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,03087574 0,0993142 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,03087574 0,09918161 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,03087574 0,09904936 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,03087574 0,09891747 ! Schwann cell development GO:0014044 15 6 0,000 0,03087574 0,09878593 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,03087574 0,09865474 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,03087574 0,0985239 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,03087574 0,09839341 ! subpallium development GO:0021544 10 6 0,000 0,03087574 0,09826326 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,03087574 0,09813345 ! histone ubiquitination GO:0016574 8 6 0,000 0,03087574 0,09800399 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,03087574 0,09787487 ! maintenance of organ identity GO:0048496 9 6 0,000 0,03087574 0,09774608 ! G2 phase GO:0051319 16 6 0,000 0,03087574 0,09761764 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,03087574 0,09748953 ! establishment of planar polarity GO:0001736 7 6 0,000 0,03087574 0,09736176 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,03087574 0,09723432 ! membrane to membrane docking GO:0022614 14 6 0,000 0,03087574 0,09710722 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,03087574 0,09698045 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,03087574 0,09685401 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,03087574 0,09672789 ! receptor internalization GO:0031623 10 6 0,000 0,03087574 0,09660211 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,03087574 0,09647665 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,03087574 0,09635152 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,03087574 0,09622671 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,03087574 0,09610223 ! protein deubiquitination GO:0016579 14 6 0,000 0,03087574 0,09597807 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 0,03087574 0,09585422 ! protein destabilization GO:0031648 9 6 0,000 0,03087574 0,0957307 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,03087574 0,09560749 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,03087574 0,0954846 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,03087574 0,09536203 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,03087574 0,09523977 ! progesterone metabolic process GO:0042448 10 6 0,000 0,03087574 0,09511783 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,03087574 0,09499619 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,03087574 0,09487487 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,03087574 0,09475386 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,03087574 0,09463315 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,03087574 0,09451275 ! determination of adult lifespan GO:0008340 15 6 0,000 0,03087574 0,09439266 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,03087574 0,09427287 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,03087574 0,09415339 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,03087574 0,09403421 ! catecholamine transport GO:0051937 9 6 0,000 0,03087574 0,09391533 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,03087574 0,09379675 ! sensory cilium assembly GO:0035058 10 6 0,000 0,03087574 0,09367846 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,03087574 0,09356048 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,03087574 0,0934428 ! maternal placenta development GO:0001893 12 6 0,000 0,03087574 0,09332541 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,03087574 0,09320831 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,03087574 0,09309151 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,03087574 0,092975 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,03087574 0,09285878 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,03087574 0,09274285 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,03087574 0,09262721 ! activation of phospholipase C activity GO:0007202 103 54 1,000 0,03237778 0,09701237 GO:0010863|positive regulation of phospholipase C activity, ! negative regulation of cytoskeleton organization GO:0051494 124 54 1,000 0,03237778 0,09689171 ! positive regulation of caspase activity GO:0043280 95 55 1,000 0,03348677 0,10008593 GO:0010952|positive regulation of peptidase activity, ! positive regulation of phospholipase activity GO:0010518 104 55 1,000 0,03348677 0,09996176 ! aging GO:0007568 103 55 1,000 0,03348677 0,09983789 ! regulation of multicellular organism growth GO:0040014 85 55 1,000 0,03348677 0,09971433 ! RNA elongation GO:0006354 79 55 1,000 0,03348677 0,09959107 ! negative regulation of cell motion GO:0051271 134 55 1,000 0,03348677 0,09946812 ! skeletal muscle fiber development GO:0048741 111 56 1,000 0,03461048 0,10267919 ! regulation of DNA replication GO:0006275 101 56 1,000 0,03461048 0,10255274 ! positive regulation of organelle organization GO:0010638 100 56 1,000 0,03461048 0,10242659 ! regulation of bone remodeling GO:0046850 137 57 1,000 0,03574872 0,10566515 ! muscle fiber development GO:0048747 112 57 1,000 0,03574872 0,1055355 ! lipid modification GO:0030258 97 57 1,000 0,03574872 0,10540616 ! regulation of phospholipase activity GO:0010517 106 57 1,000 0,03574872 0,10527715 ! maintenance of location GO:0051235 118 57 1,000 0,03574872 0,10514845 ! tRNA transcription GO:0009304 14 7 0,000 0,03592879 0,10554905 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,03592879 0,10542033 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,03592879 0,10529193 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,03592879 0,10516383 ! regulation of helicase activity GO:0051095 15 7 0,000 0,03592879 0,10503605 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,03592879 0,10490858 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,03592879 0,10478142 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,03592879 0,10465456 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,03592879 0,10452802 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,03592879 0,10440178 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,03592879 0,10427584 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,03592879 0,10415021 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,03592879 0,10402487 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,03592879 0,10389984 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,03592879 0,10377511 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,03592879 0,10365068 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,03592879 0,10352655 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 0,03592879 0,10340272 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,03592879 0,10327918 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,03592879 0,10315593 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,03592879 0,10303298 ! glycolipid transport GO:0046836 10 7 0,000 0,03592879 0,10291032 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,03592879 0,10278796 GO:0051923|sulfation, ! neuron adhesion GO:0007158 12 7 0,000 0,03592879 0,10266588 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,03592879 0,10254409 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,03592879 0,1024226 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,03592879 0,10230139 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,03592879 0,10218046 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,03592879 0,10205982 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,03592879 0,10193947 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,03592879 0,1018194 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,03592879 0,10169961 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,03592879 0,10158011 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,03592879 0,10146088 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,03592879 0,10134194 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,03592879 0,10122327 ! lipoprotein transport GO:0042953 14 7 0,000 0,03592879 0,10110488 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,03592879 0,10098676 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,03592879 0,10086893 ! rhythmic behavior GO:0007622 15 7 0,000 0,03592879 0,10075136 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,03592879 0,10063408 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,03592879 0,10051706 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,03592879 0,10040031 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,03592879 0,10028384 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,03592879 0,10016764 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,03592879 0,1000517 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,03592879 0,09993604 ! mechanosensory behavior GO:0007638 14 7 0,000 0,03592879 0,09982064 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,03592879 0,0997055 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,03592879 0,09959063 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,03592879 0,09947603 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,03592879 0,09936169 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,03592879 0,09924761 ! spinal cord patterning GO:0021511 13 7 0,000 0,03592879 0,0991338 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,03592879 0,09902024 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,03592879 0,09890695 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,03592879 0,09879391 ! adrenal gland development GO:0030325 17 7 0,000 0,03592879 0,09868113 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,03592879 0,09856861 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,03592879 0,09845634 ! ovulation GO:0030728 9 7 0,000 0,03592879 0,09834434 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,03592879 0,09823258 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,03592879 0,09812108 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,03592879 0,09800983 ! microtubule nucleation GO:0007020 20 7 0,000 0,03592879 0,09789883 ! proline biosynthetic process GO:0006561 10 7 0,000 0,03592879 0,09778809 ! thyroid hormone generation GO:0006590 13 7 0,000 0,03592879 0,09767759 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,03592879 0,09756735 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,03592879 0,09745735 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,03592879 0,0973476 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,03592879 0,0972381 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,03592879 0,09712884 ! galactose metabolic process GO:0006012 13 7 0,000 0,03592879 0,09701983 ! vesicle fusion GO:0006906 17 7 0,000 0,03592879 0,09691107 ! response to dietary excess GO:0002021 8 7 0,000 0,03592879 0,09680254 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,03592879 0,09669426 ! intracellular pH reduction GO:0051452 11 7 0,000 0,03592879 0,09658622 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,03592879 0,09647843 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,03592879 0,09637087 ! organ growth GO:0035265 15 7 0,000 0,03592879 0,09626355 ! purine salvage GO:0043101 10 7 0,000 0,03592879 0,09615647 ! nucleoside transport GO:0015858 8 7 0,000 0,03592879 0,09604963 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,03592879 0,09594303 ! parturition GO:0007567 14 7 0,000 0,03592879 0,09583666 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,03592879 0,09573053 ! rRNA modification GO:0000154 14 7 0,000 0,03592879 0,09562464 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,03592879 0,09551897 ! spindle checkpoint GO:0031577 15 7 0,000 0,03592879 0,09541354 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,03592879 0,09530835 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,03592879 0,09520338 ! macrophage differentiation GO:0030225 11 7 0,000 0,03592879 0,09509865 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,03592879 0,09499414 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,03592879 0,09488987 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,03592879 0,09478582 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,03592879 0,09468201 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 0,03592879 0,09457841 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,03592879 0,09447505 ! fibrinolysis GO:0042730 10 7 0,000 0,03592879 0,09437191 ! eating behavior GO:0042755 7 7 0,000 0,03592879 0,094269 ! B cell lineage commitment GO:0002326 21 7 0,000 0,03592879 0,09416631 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,03592879 0,09406384 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,03592879 0,0939616 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,03592879 0,09385958 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,03592879 0,09375778 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,03592879 0,0936562 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,03592879 0,09355484 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,03592879 0,0934537 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,03592879 0,09335278 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,03592879 0,09325207 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,03592879 0,09315158 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,03592879 0,09305131 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,03592879 0,09295126 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,03592879 0,09285142 ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,03592879 0,09275179 ! T cell lineage commitment GO:0002360 16 7 0,000 0,03592879 0,09265238 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,03592879 0,09255318 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,03592879 0,09245419 ! oxygen homeostasis GO:0032364 12 7 0,000 0,03592879 0,09235542 ! transcription termination GO:0006353 13 7 0,000 0,03592879 0,09225685 ! response to tumor cell GO:0002347 13 7 0,000 0,03592879 0,0921585 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,03592879 0,09206035 ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,03592879 0,09196242 ! axonal fasciculation GO:0007413 18 7 0,000 0,03592879 0,09186469 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,03592879 0,09176717 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,03592879 0,09166985 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,03592879 0,09157274 ! diuresis GO:0030146 12 7 0,000 0,03592879 0,09147584 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,03592879 0,09137914 ! thiamin metabolic process GO:0006772 7 7 0,000 0,03592879 0,09128265 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,03592879 0,09118636 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,03592879 0,09109027 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,03592879 0,09099439 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,03592879 0,09089871 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,03592879 0,09080323 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,03592879 0,09070794 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,03592879 0,09061286 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,03592879 0,09051798 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,03592879 0,0904233 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,03592879 0,09032881 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,03592879 0,09023452 ! lymph node development GO:0048535 10 7 0,000 0,03592879 0,09014043 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,03592879 0,09004653 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,03592879 0,08995283 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,03592879 0,08985932 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,03592879 0,08976601 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,03592879 0,08967289 ! adult feeding behavior GO:0008343 9 7 0,000 0,03592879 0,08957997 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,03592879 0,08948724 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,03592879 0,0893947 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,03592879 0,08930235 ! muscle adaptation GO:0043500 14 7 0,000 0,03592879 0,08921019 ! retina homeostasis GO:0001895 12 7 0,000 0,03592879 0,08911822 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,03592879 0,08902644 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,03592879 0,08893485 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,03592879 0,08884344 ! protein prenylation GO:0018342 18 7 0,000 0,03592879 0,08875223 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,03592879 0,0886612 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,03592879 0,08857036 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,03592879 0,0884797 ! regulation of tissue remodeling GO:0034103 140 58 1,000 0,03690132 0,09078177 ! positive regulation of lipase activity GO:0060193 108 58 1,000 0,03690132 0,09068904 ! skeletal system morphogenesis GO:0048705 105 59 1,000 0,03806808 0,09346103 ! DNA catabolic process GO:0006308 86 59 1,000 0,03806808 0,09336575 ! integrin-mediated signaling pathway GO:0007229 135 59 1,000 0,03806808 0,09327068 ! establishment of organelle localization GO:0051656 109 59 1,000 0,03806808 0,09317579 ! mesoderm development GO:0007498 119 61 1,000 0,04044343 0,09888911 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,04095566 0,10003993 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,04095566 0,09993847 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,04095566 0,09983721 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,04095566 0,09973616 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,04095566 0,09963532 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,04095566 0,09953468 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,04095566 0,09943424 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,04095566 0,099334 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,04095566 0,09923397 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,04095566 0,09913413 ! meiotic prophase I GO:0007128 13 8 0,000 0,04095566 0,0990345 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,04095566 0,09893507 ! oligopeptide transport GO:0006857 15 8 0,000 0,04095566 0,09883584 ! UTP metabolic process GO:0046051 8 8 0,000 0,04095566 0,0987368 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,04095566 0,09863797 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,04095566 0,09853933 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,04095566 0,09844089 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,04095566 0,09834264 ! succinate metabolic process GO:0006105 14 8 0,000 0,04095566 0,0982446 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,04095566 0,09814674 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,04095566 0,09804908 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,04095566 0,09795162 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,04095566 0,09785435 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,04095566 0,09775727 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,04095566 0,09766039 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,04095566 0,09756369 ! reflex GO:0060004 16 8 0,000 0,04095566 0,09746719 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,04095566 0,09737088 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,04095566 0,09727476 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,04095566 0,09717883 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,04095566 0,09708308 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,04095566 0,09698753 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,04095566 0,09689216 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,04095566 0,09679698 ! pigment granule organization GO:0048753 16 8 0,000 0,04095566 0,09670199 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,04095566 0,09660719 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,04095566 0,09651257 ! astrocyte differentiation GO:0048708 18 8 0,000 0,04095566 0,09641813 ! histidine metabolic process GO:0006547 16 8 0,000 0,04095566 0,09632388 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,04095566 0,09622981 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,04095566 0,09613593 ! glycine catabolic process GO:0006546 13 8 0,000 0,04095566 0,09604223 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,04095566 0,09594871 ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,04095566 0,09585538 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,04095566 0,09576223 ! melanin metabolic process GO:0006582 15 8 0,000 0,04095566 0,09566925 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,04095566 0,09557646 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,04095566 0,09548385 ! macrophage activation GO:0042116 12 8 0,000 0,04095566 0,09539141 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,04095566 0,09529916 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,04095566 0,09520708 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,04095566 0,09511518 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,04095566 0,09502346 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,04095566 0,09493192 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,04095566 0,09484055 ! osteoblast development GO:0002076 16 8 0,000 0,04095566 0,09474936 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,04095566 0,09465834 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,04095566 0,09456749 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,04095566 0,09447683 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,04095566 0,09438633 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,04095566 0,09429601 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,04095566 0,09420586 ! response to UV-B GO:0010224 16 8 0,000 0,04095566 0,09411588 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,04095566 0,09402608 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,04095566 0,09393644 ! intermediate filament organization GO:0045109 12 8 0,000 0,04095566 0,09384698 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,04095566 0,09375769 ! cellular extravasation GO:0045123 12 8 0,000 0,04095566 0,09366856 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,04095566 0,09357961 ! response to antibiotic GO:0046677 11 8 0,000 0,04095566 0,09349083 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,04095566 0,09340221 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,04095566 0,09331376 ! response to tropane GO:0014073 15 8 0,000 0,04095566 0,09322548 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,04095566 0,09313736 ! melanosome transport GO:0032402 13 8 0,000 0,04095566 0,09304941 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,04095566 0,09296163 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,04095566 0,09287401 ! mast cell activation GO:0045576 14 8 0,000 0,04095566 0,09278656 ! multicellular organismal aging GO:0010259 18 8 0,000 0,04095566 0,09269928 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,04095566 0,09261215 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,04095566 0,09252519 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,04095566 0,0924384 ! nucleosome disassembly GO:0006337 14 8 0,000 0,04095566 0,09235176 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,04095566 0,09226529 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,04095566 0,09217898 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,04095566 0,09209283 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,04095566 0,09200684 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,04095566 0,09192102 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,04095566 0,09183535 ! intracellular lipid transport GO:0032365 13 8 0,000 0,04095566 0,09174984 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,04095566 0,09166449 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,04095566 0,0915793 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,04095566 0,09149427 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,04095566 0,0914094 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,04095566 0,09132468 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,04095566 0,09124012 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,04095566 0,09115572 ! hormone catabolic process GO:0042447 17 8 0,000 0,04095566 0,09107147 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,04095566 0,09098738 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,04095566 0,09090344 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,04095566 0,09081966 ! ATP catabolic process GO:0006200 11 8 0,000 0,04095566 0,09073603 ! blastocyst growth GO:0001832 19 8 0,000 0,04095566 0,09065256 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,04095566 0,09056924 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,04095566 0,09048607 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,04095566 0,09040305 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,04095566 0,09032019 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,04095566 0,09023748 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,04095566 0,09015492 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,04095566 0,09007251 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,04095566 0,08999026 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,04095566 0,08990815 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,04095566 0,08982619 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,04095566 0,08974438 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,04095566 0,08966272 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,04095566 0,08958121 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,04095566 0,08949985 GO:0000076|DNA replication checkpoint, ! NAD biosynthetic process GO:0009435 13 8 0,000 0,04095566 0,08941863 ! viral reproductive process GO:0022415 126 62 1,000 0,04165166 0,09085574 ! regulation of homeostatic process GO:0032844 134 62 1,000 0,04165166 0,09077345 ! cellular amino acid catabolic process GO:0009063 101 63 1,000 0,04287336 0,0933514 ! germ cell development GO:0007281 118 65 1,000 0,0453565 0,09866885 ! axon extension GO:0048675 15 9 0,000 0,04595649 0,09988376 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,04595649 0,09979361 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,04595649 0,09970363 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,04595649 0,09961381 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,04595649 0,09952414 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,04595649 0,09943464 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,04595649 0,0993453 ! phosphate transport GO:0006817 19 9 0,000 0,04595649 0,09925613 ! reproductive behavior GO:0019098 19 9 0,000 0,04595649 0,09916711 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,04595649 0,09907825 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,04595649 0,09898955 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,04595649 0,09890101 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,04595649 0,09881262 ! GTP metabolic process GO:0046039 9 9 0,000 0,04595649 0,0987244 ! RNA methylation GO:0001510 15 9 0,000 0,04595649 0,09863633 ! elastic fiber assembly GO:0048251 15 9 0,000 0,04595649 0,09854842 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,04595649 0,09846066 ! artery development GO:0060840 24 9 0,000 0,04595649 0,09837306 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,04595649 0,09828562 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,04595649 0,09819833 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,04595649 0,0981112 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,04595649 0,09802422 ! chemosensory behavior GO:0007635 20 9 0,000 0,04595649 0,0979374 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,04595649 0,09785073 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,04595649 0,09776421 ! leukocyte degranulation GO:0043299 16 9 0,000 0,04595649 0,09767785 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,04595649 0,09759164 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,04595649 0,09750558 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,04595649 0,09741967 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,04595649 0,09733391 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,04595649 0,09724831 ! protein targeting to ER GO:0045047 22 9 0,000 0,04595649 0,09716285 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,04595649 0,09707755 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,04595649 0,09699239 ! T cell selection GO:0045058 23 9 0,000 0,04595649 0,09690738 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,04595649 0,09682253 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,04595649 0,09673782 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,04595649 0,09665326 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,04595649 0,09656884 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,04595649 0,09648458 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,04595649 0,09640046 ! mannose metabolic process GO:0006013 13 9 0,000 0,04595649 0,09631648 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,04595649 0,09623266 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,04595649 0,09614898 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,04595649 0,09606544 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,04595649 0,09598205 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,04595649 0,09589881 ! ruffle organization GO:0031529 15 9 0,000 0,04595649 0,09581571 ! retinol metabolic process GO:0042572 18 9 0,000 0,04595649 0,09573275 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,04595649 0,09564993 ! behavioral fear response GO:0001662 22 9 0,000 0,04595649 0,09556726 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,04595649 0,09548474 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,04595649 0,09540235 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,04595649 0,09532011 GO:0030204|chondroitin sulfate metabolic process, ! oligodendrocyte development GO:0014003 10 9 0,000 0,04595649 0,09523801 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,04595649 0,09515605 ! segment specification GO:0007379 13 9 0,000 0,04595649 0,09507423 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,04595649 0,09499255 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,04595649 0,09491101 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,04595649 0,09482961 ! response to amine stimulus GO:0014075 13 9 0,000 0,04595649 0,09474835 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,04595649 0,09466723 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,04595649 0,09458625 ! erythrocyte development GO:0048821 15 9 0,000 0,04595649 0,09450541 ! gas homeostasis GO:0033483 16 9 0,000 0,04595649 0,0944247 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,04595649 0,09434413 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,04595649 0,0942637 ! renal water homeostasis GO:0003091 14 9 0,000 0,04595649 0,09418341 ! postreplication repair GO:0006301 22 9 0,000 0,04595649 0,09410325 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,04595649 0,09402323 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,04595649 0,09394335 ! icosanoid secretion GO:0032309 15 9 0,000 0,04595649 0,0938636 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,04595649 0,09378399 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,04595649 0,09370451 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,04595649 0,09362517 ! regulation of cell division GO:0051302 15 9 0,000 0,04595649 0,09354596 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,04595649 0,09346688 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,04595649 0,09338794 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,04595649 0,09330913 ! sterol catabolic process GO:0016127 11 9 0,000 0,04595649 0,09323046 GO:0006707|cholesterol catabolic process, ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,04595649 0,09315192 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,04595649 0,09307351 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,04595649 0,09299523 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,04595649 0,09291708 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,04595649 0,09283906 ! musculoskeletal movement GO:0050881 14 9 0,000 0,04595649 0,09276118 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,04595649 0,09268342 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,04595649 0,0926058 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,04595649 0,0925283 ! purine base metabolic process GO:0006144 21 9 0,000 0,04595649 0,09245094 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,04595649 0,0923737 ! pigment granule transport GO:0051904 17 9 0,000 0,04595649 0,0922966 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,04595649 0,09221962 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,04595649 0,09214277 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,04595649 0,09206605 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,04595649 0,09198945 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,04595649 0,09191299 ! mitochondrion localization GO:0051646 15 9 0,000 0,04595649 0,09183665 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 1,000 0,0466176 0,09308046 ! actin filament organization GO:0007015 148 66 1,000 0,0466176 0,09300328 ! developmental maturation GO:0021700 116 66 1,000 0,0466176 0,09292623 ! activation of MAPK activity GO:0000187 115 67 1,000 0,0478915 0,09538655 ! homeostasis of number of cells GO:0048872 114 67 1,000 0,0478915 0,09530766 ! adaptive immune response GO:0002250 119 67 1,000 0,0478915 0,09522889 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! viral reproduction GO:0016032 134 68 1,000 0,04917803 0,09770632 ! regulation of lipase activity GO:0060191 130 68 1,000 0,04917803 0,0976257 ! cell cycle checkpoint GO:0000075 137 69 1,000 0,05047703 0,10012179 ! cAMP-mediated signaling GO:0019933 120 69 1,000 0,05047703 0,10003932 ! urogenital system development GO:0001655 137 69 1,000 0,05047703 0,09995698 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,05093141 0,10077383 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,05093141 0,10069102 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,05093141 0,10060836 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,05093141 0,10052582 ! synapsis GO:0007129 13 10 0,000 0,05093141 0,10044342 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,05093141 0,10036116 ! N-glycan processing GO:0006491 20 10 0,000 0,05093141 0,10027903 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,05093141 0,10019704 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,05093141 0,10011518 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,05093141 0,10003345 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,05093141 0,09995186 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,05093141 0,0998704 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,05093141 0,09978907 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,05093141 0,09970787 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,05093141 0,09962681 ! androgen metabolic process GO:0008209 17 10 0,000 0,05093141 0,09954588 ! phospholipid efflux GO:0033700 16 10 0,000 0,05093141 0,09946508 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,05093141 0,09938441 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,05093141 0,09930387 ! pathogenesis GO:0009405 13 10 0,000 0,05093141 0,09922346 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,05093141 0,09914319 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,05093141 0,09906304 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,05093141 0,09898302 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,05093141 0,09890313 ! endoderm development GO:0007492 16 10 0,000 0,05093141 0,09882337 ! arginine catabolic process GO:0006527 13 10 0,000 0,05093141 0,09874374 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,05093141 0,09866423 ! proline metabolic process GO:0006560 13 10 0,000 0,05093141 0,09858486 ! L-serine metabolic process GO:0006563 18 10 0,000 0,05093141 0,09850561 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,05093141 0,09842649 ! V(D)J recombination GO:0033151 28 10 0,000 0,05093141 0,09834749 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,05093141 0,09826863 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,05093141 0,09818989 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,05093141 0,09811127 ! B cell proliferation GO:0042100 18 10 0,000 0,05093141 0,09803278 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,05093141 0,09795442 ! multicellular organism growth GO:0035264 18 10 0,000 0,05093141 0,09787618 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,05093141 0,09779807 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,05093141 0,09772008 ! epithelial cell development GO:0002064 20 10 0,000 0,05093141 0,09764221 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,05093141 0,09756447 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,05093141 0,09748686 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,05093141 0,09740936 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,05093141 0,09733199 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,05093141 0,09725474 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,05093141 0,09717762 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 0,05093141 0,09710062 ! copper ion homeostasis GO:0055070 13 10 0,000 0,05093141 0,09702373 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,05093141 0,09694698 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,05093141 0,09687034 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,05093141 0,09679382 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,05093141 0,09671742 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,05093141 0,09664115 ! blastoderm segmentation GO:0007350 18 10 0,000 0,05093141 0,09656499 ! response to dsRNA GO:0043331 20 10 0,000 0,05093141 0,09648896 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,05093141 0,09641304 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,05093141 0,09633725 ! melanosome localization GO:0032400 16 10 0,000 0,05093141 0,09626157 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,05093141 0,09618601 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,05093141 0,09611057 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,05093141 0,09603525 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,05093141 0,09596004 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,05093141 0,09588496 ! mRNA cleavage GO:0006379 17 10 0,000 0,05093141 0,09580999 ! protein sumoylation GO:0016925 15 10 0,000 0,05093141 0,09573514 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,05093141 0,0956604 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,05093141 0,09558579 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,05093141 0,09551128 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,05093141 0,0954369 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,05093141 0,09536263 ! salivary gland development GO:0007431 27 10 0,000 0,05093141 0,09528847 ! prophase GO:0051324 15 10 0,000 0,05093141 0,09521443 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,05093141 0,09514051 ! apical protein localization GO:0045176 15 10 0,000 0,05093141 0,0950667 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,05093141 0,09499301 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,05093141 0,09491942 ! midbrain development GO:0030901 13 10 0,000 0,05093141 0,09484596 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,05093141 0,0947726 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,05093141 0,09469936 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,05093141 0,09462624 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,05093141 0,09455322 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,05093141 0,09448032 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,05093141 0,09440753 ! detection of calcium ion GO:0005513 23 10 0,000 0,05093141 0,09433486 ! oocyte development GO:0048599 17 10 0,000 0,05093141 0,09426229 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,05093141 0,09418984 ! blastocyst formation GO:0001825 17 10 0,000 0,05093141 0,09411749 ! cerebellar cortex development GO:0021695 15 10 0,000 0,05093141 0,09404526 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,05093141 0,09397314 ! activation of innate immune response GO:0002218 12 10 0,000 0,05093141 0,09390113 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,05093141 0,09382923 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,05093141 0,09375744 ! response to nicotine GO:0035094 20 10 0,000 0,05093141 0,09368576 ! establishment of cell polarity GO:0030010 16 10 0,000 0,05093141 0,09361419 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,05093141 0,09354273 ! amine catabolic process GO:0009310 117 71 1,000 0,05311177 0,09747286 ! reproductive structure development GO:0048608 113 71 1,000 0,05311177 0,09739857 ! regulation of caspase activity GO:0043281 122 72 1,000 0,0544472 0,09977148 ! phosphoinositide metabolic process GO:0030384 128 72 1,000 0,0544472 0,09969555 ! carbohydrate transport GO:0008643 110 72 1,000 0,0544472 0,09961974 ! axon guidance GO:0007411 139 73 1,000 0,05579444 0,10200716 ! respiratory burst GO:0045730 17 11 0,000 0,05588055 0,10208702 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,05588055 0,10200957 ! neuron fate specification GO:0048665 17 11 0,000 0,05588055 0,10193223 ! telencephalon cell migration GO:0022029 20 11 0,000 0,05588055 0,10185501 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,05588055 0,1017779 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,05588055 0,10170091 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,05588055 0,10162404 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,05588055 0,10154729 ! response to pain GO:0048265 24 11 0,000 0,05588055 0,10147065 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,05588055 0,10139412 ! T cell proliferation GO:0042098 26 11 0,000 0,05588055 0,10131772 ! bone resorption GO:0045453 16 11 0,000 0,05588055 0,10124142 ! ventral spinal cord development GO:0021517 21 11 0,000 0,05588055 0,10116524 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,05588055 0,10108918 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,05588055 0,10101323 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,05588055 0,10093739 ! melanocyte differentiation GO:0030318 21 11 0,000 0,05588055 0,10086167 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,05588055 0,10078606 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,05588055 0,10071057 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,05588055 0,10063519 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,05588055 0,10055992 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,05588055 0,10048476 ! lipid digestion GO:0044241 18 11 0,000 0,05588055 0,10040972 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,05588055 0,10033478 ! UV protection GO:0009650 19 11 0,000 0,05588055 0,10025996 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,05588055 0,10018525 ! temperature homeostasis GO:0001659 17 11 0,000 0,05588055 0,10011065 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,05588055 0,10003617 ! negative regulation of ossification GO:0030279 26 11 0,000 0,05588055 0,09996179 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,05588055 0,09988752 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,05588055 0,09981337 ! regulation of organ growth GO:0046620 13 11 0,000 0,05588055 0,09973932 ! pigment granule localization GO:0051875 20 11 0,000 0,05588055 0,09966539 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,05588055 0,09959156 ! vasoconstriction GO:0042310 18 11 0,000 0,05588055 0,09951785 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,05588055 0,09944424 ! embryonic axis specification GO:0000578 18 11 0,000 0,05588055 0,09937074 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,05588055 0,09929735 ! snRNA metabolic process GO:0016073 24 11 0,000 0,05588055 0,09922407 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,05588055 0,09915089 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,05588055 0,09907783 GO:0006809|nitric oxide biosynthetic process, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,05588055 0,09900487 ! zymogen activation GO:0031638 15 11 0,000 0,05588055 0,09893202 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,05588055 0,09885927 ! neuroblast proliferation GO:0007405 24 11 0,000 0,05588055 0,09878663 ! nucleosome positioning GO:0016584 15 11 0,000 0,05588055 0,0987141 ! regulation of isotype switching GO:0045191 22 11 0,000 0,05588055 0,09864168 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,05588055 0,09856936 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,05588055 0,09849715 ! acid secretion GO:0046717 18 11 0,000 0,05588055 0,09842504 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,05588055 0,09835304 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,05588055 0,09828115 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,05588055 0,09820936 ! oocyte differentiation GO:0009994 18 11 0,000 0,05588055 0,09813767 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,05588055 0,09806609 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,05588055 0,09799461 ! cholesterol efflux GO:0033344 19 11 0,000 0,05588055 0,09792324 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,05588055 0,09785197 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,05588055 0,09778081 ! germ cell migration GO:0008354 25 11 0,000 0,05588055 0,09770974 ! embryonic gut development GO:0048566 15 11 0,000 0,05588055 0,09763879 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,05588055 0,09756793 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,05588055 0,09749718 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,05588055 0,09742653 ! defense response to fungus GO:0050832 13 11 0,000 0,05588055 0,09735598 ! developmental induction GO:0031128 19 11 0,000 0,05588055 0,09728553 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,05588055 0,09721519 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,05588055 0,09714495 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,05588055 0,09707481 ! sequestering of metal ion GO:0051238 14 11 0,000 0,05588055 0,09700477 ! lamellipodium assembly GO:0030032 20 11 0,000 0,05588055 0,09693483 ! nucleus localization GO:0051647 19 11 0,000 0,05588055 0,09686499 ! regulation of synapse organization GO:0050807 17 11 0,000 0,05588055 0,09679525 ! meiosis GO:0007126 121 74 1,000 0,05715335 0,09892875 GO:0051327|M phase of meiotic cell cycle, ! regulation of endopeptidase activity GO:0052548 125 74 1,000 0,05715335 0,09885763 ! organelle localization GO:0051640 136 74 1,000 0,05715335 0,09878661 ! cell-matrix adhesion GO:0007160 163 75 1,000 0,05852377 0,1010827 ! meiotic cell cycle GO:0051321 122 75 1,000 0,05852377 0,10101018 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,06080405 0,10487064 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,06080405 0,10479551 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,06080405 0,1047205 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,06080405 0,10464559 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,06080405 0,10457079 ! mating GO:0007618 17 12 0,000 0,06080405 0,1044961 ! protein complex disassembly GO:0043241 27 12 0,000 0,06080405 0,10442151 GO:0043624|cellular protein complex disassembly, ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,06080405 0,10434703 ! hippocampus development GO:0021766 26 12 0,000 0,06080405 0,10427266 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,06080405 0,10419839 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,06080405 0,10412423 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,06080405 0,10405017 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,06080405 0,10397622 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,06080405 0,10390237 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,06080405 0,10382863 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,06080405 0,10375499 ! drug transport GO:0015893 16 12 0,000 0,06080405 0,10368146 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,06080405 0,10360803 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,06080405 0,10353471 ! polyamine metabolic process GO:0006595 17 12 0,000 0,06080405 0,10346148 ! focal adhesion formation GO:0048041 35 12 0,000 0,06080405 0,10338837 ! mitotic spindle organization GO:0007052 21 12 0,000 0,06080405 0,10331535 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,06080405 0,10324244 ! forebrain cell migration GO:0021885 21 12 0,000 0,06080405 0,10316963 ! asymmetric protein localization GO:0008105 20 12 0,000 0,06080405 0,10309693 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,06080405 0,10302432 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,06080405 0,10295182 ! entry into host cell GO:0030260 32 12 0,000 0,06080405 0,10287942 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,06080405 0,10280712 ! monoamine transport GO:0015844 18 12 0,000 0,06080405 0,10273493 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,06080405 0,10266283 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,06080405 0,10259084 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,06080405 0,10251895 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,06080405 0,10244716 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,06080405 0,10237546 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,06080405 0,10230387 ! protein homotetramerization GO:0051289 21 12 0,000 0,06080405 0,10223238 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,06080405 0,10216099 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,06080405 0,1020897 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,06080405 0,10201851 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,06080405 0,10194741 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,06080405 0,10187642 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,06080405 0,10180552 ! cranial nerve development GO:0021545 20 12 0,000 0,06080405 0,10173473 ! fucose catabolic process GO:0019317 22 12 0,000 0,06080405 0,10166403 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,06080405 0,10159343 ! histone methylation GO:0016571 26 12 0,000 0,06080405 0,10152293 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,06080405 0,10145252 ! autonomic nervous system development GO:0048483 24 12 0,000 0,06080405 0,10138222 ! gland morphogenesis GO:0022612 29 12 0,000 0,06080405 0,10131201 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,06080405 0,1012419 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,06080405 0,10117188 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,06080405 0,10110196 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,06080405 0,10103214 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,06080405 0,10096241 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,06080405 0,10089279 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,06080405 0,10082325 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,06080405 0,10075381 ! response to cold GO:0009409 17 12 0,000 0,06080405 0,10068447 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,06080405 0,10061523 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,06080405 0,10054607 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 0,06129851 0,10129411 ! response to steroid hormone stimulus GO:0048545 137 78 1,000 0,06270253 0,1035431 ! protein oligomerization GO:0051259 139 78 1,000 0,06270253 0,10347208 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 1,000 0,06411744 0,10573446 ! regulation of peptidase activity GO:0052547 134 79 1,000 0,06411744 0,10566204 ! regulation of adenylate cyclase activity GO:0045761 156 80 1,000 0,0655431 0,10793751 ! response to metal ion GO:0010038 140 80 1,000 0,0655431 0,10786368 ! muscle cell differentiation GO:0042692 159 80 1,000 0,0655431 0,10778996 ! protein import into nucleus GO:0006606 158 80 1,000 0,0655431 0,10771633 ! cGMP metabolic process GO:0046068 18 13 0,000 0,06570203 0,10790381 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,06570203 0,10783021 ! regulation of chemokine production GO:0032642 18 13 0,000 0,06570203 0,1077567 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,06570203 0,1076833 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,06570203 0,10761 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,06570203 0,10753679 ! lipid localization GO:0010876 28 13 0,000 0,06570203 0,10746369 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,06570203 0,10739068 ! organelle fusion GO:0048284 32 13 0,000 0,06570203 0,10731778 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,06570203 0,10724497 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,06570203 0,10717226 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,06570203 0,10709965 ! endocrine pancreas development GO:0031018 22 13 0,000 0,06570203 0,10702714 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,06570203 0,10695473 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,06570203 0,10688241 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,06570203 0,10681019 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,06570203 0,10673807 ! methionine metabolic process GO:0006555 27 13 0,000 0,06570203 0,10666605 ! plasma membrane organization GO:0007009 24 13 0,000 0,06570203 0,10659412 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,06570203 0,10652229 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,06570203 0,10645056 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,06570203 0,10637893 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,06570203 0,10630739 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,06570203 0,10623594 ! response to X-ray GO:0010165 25 13 0,000 0,06570203 0,1061646 ! cytokine metabolic process GO:0042107 22 13 0,000 0,06570203 0,10609335 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,06570203 0,10602219 ! exocrine system development GO:0035272 32 13 0,000 0,06570203 0,10595113 ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,06570203 0,10588016 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,06570203 0,10580929 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,06570203 0,10573852 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,06570203 0,10566784 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,06570203 0,10559725 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,06570203 0,10552676 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,06570203 0,10545636 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,06570203 0,10538606 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,06570203 0,10531585 ! regulation of cellular pH GO:0030641 22 13 0,000 0,06570203 0,10524573 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,06570203 0,10517571 ! ribosome assembly GO:0042255 17 13 0,000 0,06570203 0,10510577 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,06570203 0,10503594 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,06570203 0,10496619 ! chromatin silencing GO:0006342 26 13 0,000 0,06570203 0,10489654 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,06570203 0,10482698 ! regulation of epidermis development GO:0045682 19 13 0,000 0,06570203 0,10475751 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,06570203 0,10468814 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,06570203 0,10461885 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,06570203 0,10454966 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,06570203 0,10448056 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,06570203 0,10441155 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,06570203 0,10434263 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,06570203 0,1042738 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,06570203 0,10420507 ! embryonic placenta development GO:0001892 23 13 0,000 0,06570203 0,10413642 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,06570203 0,10406786 ! insulin secretion GO:0030073 23 13 0,000 0,06570203 0,1039994 ! actin filament polymerization GO:0030041 24 13 0,000 0,06570203 0,10393102 ! acrosome reaction GO:0007340 18 13 0,000 0,06570203 0,10386274 ! cell-substrate adhesion GO:0031589 171 81 1,000 0,06697936 0,10581243 ! nuclear import GO:0051170 161 81 1,000 0,06697936 0,105743 ! regulation of neuron differentiation GO:0045664 167 81 1,000 0,06697936 0,10567366 ! regulation of cAMP biosynthetic process GO:0030817 161 82 1,000 0,06842606 0,10788539 ! response to drug GO:0042493 143 82 1,000 0,06842606 0,10781474 ! regulation of cyclase activity GO:0031279 159 82 1,000 0,06842606 0,10774418 ! regulation of lyase activity GO:0051339 160 83 1,000 0,06988307 0,10996642 ! rRNA transcription GO:0009303 25 14 0,000 0,07057463 0,11098207 ! lactation GO:0007595 26 14 0,000 0,07057463 0,11090958 ! reproductive cellular process GO:0048610 20 14 0,000 0,07057463 0,11083718 ! tRNA modification GO:0006400 20 14 0,000 0,07057463 0,11076488 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,07057463 0,11069267 ! regulation of S phase GO:0033261 23 14 0,000 0,07057463 0,11062056 ! water transport GO:0006833 21 14 0,000 0,07057463 0,11054854 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,07057463 0,11047662 ! non-recombinational repair GO:0000726 25 14 0,000 0,07057463 0,11040479 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,07057463 0,11033305 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,07057463 0,1102614 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,07057463 0,11018985 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,07057463 0,11011839 ! RNA polyadenylation GO:0043631 30 14 0,000 0,07057463 0,11004703 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,07057463 0,10997575 ! palate development GO:0060021 31 14 0,000 0,07057463 0,10990457 ! regulated secretory pathway GO:0045055 23 14 0,000 0,07057463 0,10983348 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,07057463 0,10976248 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,07057463 0,10969158 ! arginine metabolic process GO:0006525 17 14 0,000 0,07057463 0,10962076 ! regulation of heart rate GO:0002027 24 14 0,000 0,07057463 0,10955004 ! organic alcohol transport GO:0015850 29 14 0,000 0,07057463 0,10947941 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,07057463 0,10940887 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,07057463 0,10933842 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,07057463 0,10926806 ! neutral amino acid transport GO:0015804 26 14 0,000 0,07057463 0,10919779 ! L-amino acid transport GO:0015807 30 14 0,000 0,07057463 0,10912761 ! bone mineralization GO:0030282 17 14 0,000 0,07057463 0,10905752 ! stem cell development GO:0048864 43 14 0,000 0,07057463 0,10898752 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,07057463 0,10891762 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,07057463 0,1088478 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,07057463 0,10877807 ! cerebellum development GO:0021549 21 14 0,000 0,07057463 0,10870843 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,07057463 0,10863888 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,07057463 0,10856941 ! response to gamma radiation GO:0010332 28 14 0,000 0,07057463 0,10850004 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,07057463 0,10843076 ! cofactor transport GO:0051181 26 14 0,000 0,07057463 0,10836156 ! NADP metabolic process GO:0006739 24 14 0,000 0,07057463 0,10829245 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,07057463 0,10822343 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,07057463 0,1081545 ! intestinal absorption GO:0050892 25 14 0,000 0,07057463 0,10808565 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,07057463 0,1080169 ! oxygen transport GO:0015671 21 14 0,000 0,07057463 0,10794823 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,07057463 0,10787965 ! male genitalia development GO:0030539 24 14 0,000 0,07057463 0,10781115 ! regulation of axon extension GO:0030516 37 14 0,000 0,07057463 0,10774274 ! release of cytochrome c from mitochondria GO:0001836 30 14 0,000 0,07057463 0,10767442 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,07057463 0,10760619 ! regulation of cAMP metabolic process GO:0030814 168 84 1,000 0,07135023 0,10871985 ! one-carbon metabolic process GO:0006730 154 85 1,000 0,0728274 0,11090047 ! positive regulation of cell activation GO:0050867 145 85 1,000 0,0728274 0,11083032 GO:0002696|positive regulation of leukocyte activation, ! response to inorganic substance GO:0010035 153 86 1,000 0,07431445 0,11302185 ! tube morphogenesis GO:0035239 176 86 1,000 0,07431445 0,11295046 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,07542198 0,11456142 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,07542198 0,11448914 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,07542198 0,11441695 ! superoxide anion generation GO:0042554 20 15 0,000 0,07542198 0,11434486 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,07542198 0,11427285 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,07542198 0,11420094 ! copper ion transport GO:0006825 20 15 0,000 0,07542198 0,11412911 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,07542198 0,11405738 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,07542198 0,11398573 ! sulfate transport GO:0008272 23 15 0,000 0,07542198 0,11391418 ! response to cAMP GO:0051591 22 15 0,000 0,07542198 0,11384271 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,07542198 0,11377134 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,07542198 0,11370005 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,07542198 0,11362886 ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,07542198 0,11355775 ! response to hexose stimulus GO:0009746 22 15 0,000 0,07542198 0,11348673 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,07542198 0,1134158 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,07542198 0,11334496 ! pituitary gland development GO:0021983 29 15 0,000 0,07542198 0,11327421 ! vesicle coating GO:0006901 33 15 0,000 0,07542198 0,11320355 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,07542198 0,11313297 ! regulation of exocytosis GO:0017157 22 15 0,000 0,07542198 0,11306248 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,07542198 0,11299208 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,07542198 0,11292177 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,07542198 0,11285155 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,07542198 0,11278141 ! regulation of vasodilation GO:0042312 26 15 0,000 0,07542198 0,11271136 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,07542198 0,11264139 ! histone deacetylation GO:0016575 20 15 0,000 0,07542198 0,11257152 ! mRNA splice site selection GO:0006376 38 15 0,000 0,07542198 0,11250173 ! tissue regeneration GO:0042246 26 15 0,000 0,07542198 0,11243202 ! water homeostasis GO:0030104 27 15 0,000 0,07542198 0,11236241 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,07542198 0,11229288 ! muscle maintenance GO:0046716 26 15 0,000 0,07542198 0,11222343 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,07542198 0,11215407 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,07542198 0,1120848 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,07542198 0,11201561 ! dopamine metabolic process GO:0042417 35 15 0,000 0,07542198 0,11194651 ! heme biosynthetic process GO:0006783 29 15 0,000 0,07542198 0,11187749 ! cell killing GO:0001906 29 15 0,000 0,07542198 0,11180856 ! detection of bacterium GO:0016045 18 15 0,000 0,07542198 0,11173971 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,07542198 0,11167095 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,07542198 0,11160227 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,07542198 0,11153367 ! peptide hormone processing GO:0016486 23 15 0,000 0,07542198 0,11146516 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 1,000 0,07581123 0,11197165 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 1,000 0,07581123 0,11190295 ! protein localization in nucleus GO:0034504 176 87 1,000 0,07581123 0,11183434 ! regulation of cell morphogenesis GO:0022604 215 89 1,000 0,07883341 0,11622131 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,08024421 0,11822876 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,08024421 0,11815641 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,08024421 0,11808414 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,08024421 0,11801196 ! bone remodeling GO:0046849 27 16 0,000 0,08024421 0,11793987 ! filopodium assembly GO:0046847 32 16 0,000 0,08024421 0,11786787 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,08024421 0,11779596 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,08024421 0,11772413 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,08024421 0,11765239 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,08024421 0,11758074 ! startle response GO:0001964 28 16 0,000 0,08024421 0,11750917 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,08024421 0,1174377 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,08024421 0,1173663 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,08024421 0,117295 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,08024421 0,11722378 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,08024421 0,11715265 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,08024421 0,11708161 ! protein polyubiquitination GO:0000209 34 16 0,000 0,08024421 0,11701065 ! glutamate metabolic process GO:0006536 22 16 0,000 0,08024421 0,11693978 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,08024421 0,11686899 ! response to osmotic stress GO:0006970 25 16 0,000 0,08024421 0,11679829 ! lysosomal transport GO:0007041 26 16 0,000 0,08024421 0,11672767 ! fructose metabolic process GO:0006000 25 16 0,000 0,08024421 0,11665714 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,08024421 0,1165867 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,08024421 0,11651634 ! intermediate filament-based process GO:0045103 32 16 0,000 0,08024421 0,11644606 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,08024421 0,11637587 ! negative regulation of immune response GO:0050777 35 16 0,000 0,08024421 0,11630577 ! axon cargo transport GO:0008088 43 16 0,000 0,08024421 0,11623574 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,08024421 0,11616581 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,08024421 0,11609595 ! DNA replication initiation GO:0006270 27 16 0,000 0,08024421 0,11602618 ! neuron recognition GO:0008038 35 16 0,000 0,08024421 0,1159565 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,08024421 0,1158869 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,08024421 0,11581738 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,08024421 0,11574794 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,08024421 0,11567859 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,08024421 0,11560932 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,08024421 0,11554014 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,08024421 0,11547104 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,08024421 0,11540202 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,08024421 0,11533308 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,08024421 0,11526422 ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,08024421 0,11519545 ! defense response to virus GO:0051607 37 16 0,000 0,08024421 0,11512676 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 1,000 0,08035854 0,11522207 ! sex differentiation GO:0007548 145 90 1,000 0,08035854 0,11515345 ! regulation of nucleotide metabolic process GO:0006140 182 93 1,000 0,08498842 0,12171557 ! carbohydrate biosynthetic process GO:0016051 141 93 1,000 0,08498842 0,12164316 ! regulation of membrane potential GO:0042391 164 93 1,000 0,08498842 0,12157084 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,08504145 0,12157441 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,08504145 0,12150221 ! metencephalon development GO:0022037 30 17 0,000 0,08504145 0,1214301 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,08504145 0,12135808 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,08504145 0,12128614 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,08504145 0,12121429 ! endothelial cell migration GO:0043542 28 17 0,000 0,08504145 0,12114253 ! inositol metabolic process GO:0006020 28 17 0,000 0,08504145 0,12107084 ! gene silencing by RNA GO:0031047 36 17 0,000 0,08504145 0,12099925 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,08504145 0,12092773 ! glial cell development GO:0021782 27 17 0,000 0,08504145 0,12085631 ! limbic system development GO:0021761 36 17 0,000 0,08504145 0,12078496 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,08504145 0,1207137 ! adult walking behavior GO:0007628 33 17 0,000 0,08504145 0,12064253 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,08504145 0,12057144 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,08504145 0,12050043 ! myoblast differentiation GO:0045445 45 17 0,000 0,08504145 0,1204295 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,08504145 0,12035866 ! glycine metabolic process GO:0006544 28 17 0,000 0,08504145 0,1202879 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,08504145 0,12021723 ! NAD metabolic process GO:0019674 29 17 0,000 0,08504145 0,12014664 ! membrane budding GO:0006900 37 17 0,000 0,08504145 0,12007613 ! DNA integration GO:0015074 29 17 0,000 0,08504145 0,1200057 ! regulation of protein binding GO:0043393 33 17 0,000 0,08504145 0,11993536 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,08504145 0,1198651 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,08504145 0,11979492 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,08504145 0,11972482 ! genitalia development GO:0048806 30 17 0,000 0,08504145 0,11965481 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,08504145 0,11958488 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,08504145 0,11951503 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,08504145 0,11944526 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,08504145 0,11937557 ! steroid catabolic process GO:0006706 31 17 0,000 0,08504145 0,11930596 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,08504145 0,11923644 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,08504145 0,11916699 ! gas transport GO:0015669 25 17 0,000 0,08504145 0,11909763 ! organic cation transport GO:0015695 31 17 0,000 0,08504145 0,11902835 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,08504145 0,11895914 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,08504145 0,11889002 ! microspike assembly GO:0030035 36 17 0,000 0,08504145 0,11882098 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,08504145 0,11875202 ! forebrain development GO:0030900 188 95 1,000 0,0881191 0,12297828 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,08981382 0,12527076 ! neuron maturation GO:0042551 42 18 0,000 0,08981382 0,12519818 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,08981382 0,12512569 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,08981382 0,12505328 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,08981382 0,12498095 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,08981382 0,12490871 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,08981382 0,12483655 ! memory GO:0007613 31 18 0,000 0,08981382 0,12476447 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,08981382 0,12469248 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,08981382 0,12462057 ! patterning of blood vessels GO:0001569 39 18 0,000 0,08981382 0,12454874 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,08981382 0,12447699 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,08981382 0,12440533 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,08981382 0,12433375 ! glutamine metabolic process GO:0006541 29 18 0,000 0,08981382 0,12426225 ! response to retinoic acid GO:0032526 26 18 0,000 0,08981382 0,12419084 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,08981382 0,12411951 ! response to fungus GO:0009620 21 18 0,000 0,08981382 0,12404826 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,08981382 0,12397709 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,08981382 0,123906 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,08981382 0,12383499 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,08981382 0,12376407 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,08981382 0,12369322 ! vitamin transport GO:0051180 27 18 0,000 0,08981382 0,12362246 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,08981382 0,12355178 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,08981382 0,12348118 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,08981382 0,12341066 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,08981382 0,12334022 ! nerve development GO:0021675 28 18 0,000 0,08981382 0,12326986 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,08981382 0,12319958 ! regulation of DNA metabolic process GO:0051052 178 97 1,000 0,09128381 0,12514464 ! protein ubiquitination GO:0016567 217 97 1,000 0,09128381 0,12507337 ! carboxylic acid catabolic process GO:0046395 156 98 1,000 0,0928786 0,12718607 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 1,000 0,09448152 0,12930747 ! protein secretion GO:0009306 39 19 0,000 0,09456146 0,12934331 ! positive regulation of translation GO:0045727 30 19 0,000 0,09456146 0,12926982 ! negative regulation of defense response GO:0031348 25 19 0,000 0,09456146 0,12919641 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,09456146 0,12912309 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,09456146 0,12904985 ! skin development GO:0043588 36 19 0,000 0,09456146 0,12897669 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,09456146 0,12890362 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,09456146 0,12883062 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,09456146 0,12875772 ! bile acid metabolic process GO:0008206 29 19 0,000 0,09456146 0,12868489 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,09456146 0,12861214 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,09456146 0,12853948 ! cerebral cortex development GO:0021987 36 19 0,000 0,09456146 0,1284669 ! pigmentation during development GO:0048066 41 19 0,000 0,09456146 0,1283944 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,09456146 0,12832199 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,09456146 0,12824965 ! heme metabolic process GO:0042168 36 19 0,000 0,09456146 0,1281774 ! actin filament bundle formation GO:0051017 42 19 0,000 0,09456146 0,12810523 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,09456146 0,12803314 ! plasma membrane fusion GO:0045026 28 19 0,000 0,09456146 0,12796113 ! peptide cross-linking GO:0018149 37 19 0,000 0,09456146 0,1278892 ! protein export from nucleus GO:0006611 36 19 0,000 0,09456146 0,12781735 ! heart process GO:0003015 30 19 0,000 0,09456146 0,12774558 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,09456146 0,1276739 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,09456146 0,12760229 ! visual learning GO:0008542 36 19 0,000 0,09456146 0,12753076 ! cellular pigmentation GO:0033059 36 19 0,000 0,09456146 0,12745932 ! G1 phase GO:0051318 40 19 0,000 0,09456146 0,12738795 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,09456146 0,12731667 ! cell-cell junction organization GO:0045216 35 19 0,000 0,09456146 0,12724546 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,09456146 0,12717433 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,09456146 0,12710329 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,09456146 0,12703232 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,09456146 0,12696143 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,09456146 0,12689062 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,09456146 0,12681989 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,09456146 0,12674924 ! cilium assembly GO:0042384 37 19 0,000 0,09456146 0,12667867 ! peptide hormone secretion GO:0030072 31 19 0,000 0,09456146 0,12660817 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,0992845 0,1328579 ! positive regulation of ossification GO:0045778 47 20 0,000 0,0992845 0,13278405 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,0992845 0,13271028 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,0992845 0,13263659 ! cAMP metabolic process GO:0046058 36 20 0,000 0,0992845 0,13256299 ! response to vitamin GO:0033273 31 20 0,000 0,0992845 0,13248946 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,0992845 0,13241602 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,0992845 0,13234266 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,0992845 0,13226938 ! response to alkaloid GO:0043279 38 20 0,000 0,0992845 0,13219618 ! retinoid metabolic process GO:0001523 32 20 0,000 0,0992845 0,13212306 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,0992845 0,13205003 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,0992845 0,13197707 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,0992845 0,1319042 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,0992845 0,1318314 GO:0032392|DNA geometric change, ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,0992845 0,13175869 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,0992845 0,13168605 ! body fluid secretion GO:0007589 31 20 0,000 0,0992845 0,1316135 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,0992845 0,13154102 ! peptide secretion GO:0002790 35 20 0,000 0,0992845 0,13146863 ! stem cell differentiation GO:0048863 53 20 0,000 0,0992845 0,13139632 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,0992845 0,13132408 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,0992845 0,13125192 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,0992845 0,13117985 ! sensory perception of pain GO:0019233 30 20 0,000 0,0992845 0,13110785 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,0992845 0,13103593 ! diencephalon development GO:0021536 34 20 0,000 0,0992845 0,13096409 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,0992845 0,13089233 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,0992845 0,13082065 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,0992845 0,13074904 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,0992845 0,13067752 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,0992845 0,13060607 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,0992845 0,1305347 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,0992845 0,13046341 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,0992845 0,13039219 ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,0992845 0,13032106 ! actin filament-based movement GO:0030048 43 20 0,000 0,0992845 0,13025 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,0992845 0,13017902 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,0992845 0,13010812 ! negative regulation of translation GO:0017148 29 20 0,000 0,0992845 0,13003729 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,0992845 0,12996654 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,0992845 0,12989587 ! regulation of cell killing GO:0031341 42 21 0,000 0,10398305 0,13596914 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,10398305 0,13589528 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,10398305 0,13582151 ! hormone secretion GO:0046879 38 21 0,000 0,10398305 0,13574781 ! glycerol metabolic process GO:0006071 34 21 0,000 0,10398305 0,1356742 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,10398305 0,13560066 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,10398305 0,1355272 ! axis specification GO:0009798 38 21 0,000 0,10398305 0,13545383 ! ovarian follicle development GO:0001541 35 21 0,000 0,10398305 0,13538053 ! smooth muscle contraction GO:0006939 46 21 0,000 0,10398305 0,13530731 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,10398305 0,13523417 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,10398305 0,13516111 ! cell aging GO:0007569 44 21 0,000 0,10398305 0,13508813 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,10398305 0,13501523 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,10398305 0,1349424 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,10398305 0,13486966 ! cytolysis GO:0019835 24 21 0,000 0,10398305 0,13479699 ! vasodilation GO:0042311 39 21 0,000 0,10398305 0,1347244 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,10398305 0,13465189 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,10398305 0,13457946 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,10398305 0,13450711 ! oogenesis GO:0048477 36 21 0,000 0,10398305 0,13443483 ! collagen fibril organization GO:0030199 59 21 0,000 0,10398305 0,13436263 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,10398305 0,13429051 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,10398305 0,13421846 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,10398305 0,1341465 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,10398305 0,13407461 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,10398305 0,13400279 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,10398305 0,13393106 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,10398305 0,1338594 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,10398305 0,13378782 ! collagen catabolic process GO:0030574 28 21 0,000 0,10398305 0,13371631 ! sperm-egg recognition GO:0035036 21 21 0,000 0,10398305 0,13364488 ! gut development GO:0048565 39 21 0,000 0,10398305 0,13357353 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,10865725 0,13950338 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,10865725 0,13942898 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,10865725 0,13935466 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,10865725 0,13928041 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,10865725 0,13920625 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,10865725 0,13913217 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,10865725 0,13905816 ! regeneration GO:0031099 41 22 0,000 0,10865725 0,13898423 ! keratinization GO:0031424 28 22 0,000 0,10865725 0,13891038 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,10865725 0,13883661 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,10865725 0,13876292 ! sensory perception of taste GO:0050909 28 22 0,000 0,10865725 0,1386893 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,10865725 0,13861577 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,10865725 0,13854231 ! vacuolar transport GO:0007034 36 22 0,000 0,10865725 0,13846893 ! lysosome organization GO:0007040 41 22 0,000 0,10865725 0,13839563 ! central nervous system neuron development GO:0021954 46 22 0,000 0,10865725 0,1383224 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,10865725 0,13824925 ! fucose metabolic process GO:0006004 39 22 0,000 0,10865725 0,13817618 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,10865725 0,13810319 ! ureteric bud development GO:0001657 43 22 0,000 0,10865725 0,13803027 ! renal system process GO:0003014 41 22 0,000 0,10865725 0,13795743 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,10865725 0,13788467 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,10865725 0,13781199 ! sarcomere organization GO:0045214 30 22 0,000 0,10865725 0,13773938 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,10865725 0,13766684 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,10865725 0,13759439 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,11330722 0,14340724 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,11330722 0,14333184 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,11330722 0,14325652 ! gluconeogenesis GO:0006094 33 23 0,000 0,11330722 0,14318128 ! viral genome replication GO:0019079 41 23 0,000 0,11330722 0,14310612 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,11330722 0,14303104 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,11330722 0,14295604 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,11330722 0,14288111 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,11330722 0,14280627 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,11330722 0,1427315 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,11330722 0,14265681 ! visual behavior GO:0007632 42 23 0,000 0,11330722 0,1425822 ! regulation of DNA recombination GO:0000018 48 23 0,000 0,11330722 0,14250767 ! response to ethanol GO:0045471 46 23 0,000 0,11330722 0,14243321 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,11330722 0,14235883 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! peroxisome organization GO:0007031 37 23 0,000 0,11330722 0,14228453 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,11330722 0,14221031 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,11330722 0,14213616 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,11330722 0,1420621 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,11330722 0,14198811 GO:0051693|actin filament capping, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,11330722 0,14191419 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,11330722 0,14184036 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,11330722 0,1417666 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,11330722 0,14169291 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,11330722 0,14161931 ! fatty acid transport GO:0015908 44 23 0,000 0,11330722 0,14154578 ! platelet activation GO:0030168 37 23 0,000 0,11330722 0,14147232 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,11330722 0,14139894 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,11330722 0,14132564 ! hormone transport GO:0009914 40 23 0,000 0,11330722 0,14125242 ! cell-cell recognition GO:0009988 25 23 0,000 0,11330722 0,14117927 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,11330722 0,14110619 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,11330722 0,14103319 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,11330722 0,14096027 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,11330722 0,14088742 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,11793308 0,14656353 GO:0016444|somatic cell DNA recombination, ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,11793308 0,14648786 ! vesicle docking GO:0048278 47 24 0,000 0,11793308 0,14641228 ! spinal cord development GO:0021510 47 24 0,000 0,11793308 0,14633677 ! vacuole organization GO:0007033 43 24 0,000 0,11793308 0,14626134 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,11793308 0,14618598 ! digestive system process GO:0022600 39 24 0,000 0,11793308 0,14611071 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,11793308 0,14603551 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,11793308 0,14596039 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,11793308 0,14588534 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,11793308 0,14581038 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,11793308 0,14573549 ! membrane depolarization GO:0051899 39 24 0,000 0,11793308 0,14566067 ! pallium development GO:0021543 49 24 0,000 0,11793308 0,14558594 ! pentose metabolic process GO:0019321 35 24 0,000 0,11793308 0,14551128 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,11793308 0,1454367 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,11793308 0,14536219 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,11793308 0,14528776 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,11793308 0,14521341 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,11793308 0,14513913 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,11793308 0,14506493 ! regulation of amine transport GO:0051952 40 24 0,000 0,11793308 0,1449908 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,12253497 0,15057157 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,12253497 0,15049471 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,12253497 0,15041792 ! phototransduction GO:0007602 33 25 0,000 0,12253497 0,15034122 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,12253497 0,15026459 GO:0006479|protein amino acid methylation, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 0,000 0,12253497 0,15018804 ! sperm motility GO:0030317 31 25 0,000 0,12253497 0,15011157 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,12253497 0,15003518 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,12253497 0,14995886 ! osteoblast differentiation GO:0001649 60 25 0,000 0,12253497 0,14988263 ! neural crest cell development GO:0014032 54 25 0,000 0,12253497 0,14980647 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,12253497 0,14973038 ! negative regulation of cell development GO:0010721 73 25 0,000 0,12253497 0,14965438 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,12253497 0,14957845 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,12253497 0,1495026 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,12253497 0,14942683 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,12253497 0,14935113 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! immunoglobulin production GO:0002377 55 25 0,000 0,12253497 0,14927551 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,12253497 0,14919996 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,12253497 0,1491245 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,12253497 0,1490491 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,12253497 0,14897379 ! telomere organization GO:0032200 43 25 0,000 0,12253497 0,14889855 GO:0000723|telomere maintenance, ! liver development GO:0001889 53 25 0,000 0,12253497 0,14882339 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,12711299 0,15430568 ! embryonic pattern specification GO:0009880 44 26 0,000 0,12711299 0,15422787 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,12711299 0,15415013 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,12711299 0,15407247 ! initiation of viral infection GO:0019059 57 26 0,000 0,12711299 0,1539949 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,12711299 0,15391739 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,12711299 0,15383997 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,12711299 0,15376263 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,12711299 0,15368536 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,12711299 0,15360817 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,12711299 0,15353106 GO:0051297|centrosome organization, ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,12711299 0,15345402 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,12711299 0,15337706 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,12711299 0,15330018 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,12711299 0,15322338 ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,12711299 0,15314665 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,12711299 0,15307 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,12711299 0,15299343 ! blastocyst development GO:0001824 49 26 0,000 0,12711299 0,15291693 ! leukocyte proliferation GO:0070661 52 26 0,000 0,12711299 0,15284051 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,12711299 0,15276417 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,12711299 0,1526879 ! neuron fate commitment GO:0048663 48 27 0,000 0,13166729 0,15807959 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,13166729 0,15800074 ! iron ion transport GO:0006826 59 27 0,000 0,13166729 0,15792198 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,13166729 0,1578433 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,13166729 0,15776469 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,13166729 0,15768616 ! fat cell differentiation GO:0045444 50 27 0,000 0,13166729 0,15760771 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,13166729 0,15752934 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,13166729 0,15745104 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,13166729 0,15737282 ! male gonad development GO:0008584 44 27 0,000 0,13166729 0,15729468 ! response to toxin GO:0009636 47 27 0,000 0,13166729 0,15721662 ! base-excision repair GO:0006284 41 27 0,000 0,13166729 0,15713864 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,13166729 0,15706073 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,13166729 0,1569829 ! glutathione metabolic process GO:0006749 39 27 0,000 0,13166729 0,15690515 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,13166729 0,15682747 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,13166729 0,15674987 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,13166729 0,15667235 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,13619797 0,16198335 ! circadian rhythm GO:0007623 50 28 0,000 0,13619797 0,16190332 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,13619797 0,16182337 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,13619797 0,16174349 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,13619797 0,1616637 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,13619797 0,16158398 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,13619797 0,16150434 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,13619797 0,16142479 ! synaptogenesis GO:0007416 42 28 0,000 0,13619797 0,16134531 ! lipid oxidation GO:0034440 43 28 0,000 0,13619797 0,1612659 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,13619797 0,16118658 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,13619797 0,16110733 ! translational initiation GO:0006413 65 29 0,000 0,14070516 0,16635706 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,14070516 0,16627535 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,14070516 0,16619373 ! regulation of pH GO:0006885 43 29 0,000 0,14070516 0,16611218 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,14070516 0,16603071 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,14070516 0,16594932 ! catechol metabolic process GO:0009712 54 29 0,000 0,14070516 0,16586802 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,14070516 0,16578679 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,14070516 0,16570564 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,14070516 0,16562457 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,14070516 0,16554358 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,14070516 0,16546267 ! cell fate determination GO:0001709 60 29 0,000 0,14070516 0,16538184 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,14070516 0,16530108 ! detection of light stimulus GO:0009583 38 29 0,000 0,14070516 0,16522041 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,14070516 0,16513981 ! tissue homeostasis GO:0001894 48 29 0,000 0,14070516 0,1650593 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,14070516 0,16497886 ! phenol metabolic process GO:0018958 55 30 0,000 0,14518899 0,17015329 ! zinc ion transport GO:0006829 45 30 0,000 0,14518899 0,17007045 ! membrane docking GO:0022406 61 30 0,000 0,14518899 0,16998769 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,14518899 0,16990501 ! cell junction assembly GO:0034329 78 30 0,000 0,14518899 0,16982241 ! regulation of innate immune response GO:0045088 51 30 0,000 0,14518899 0,16973989 ! acute-phase response GO:0006953 49 30 0,000 0,14518899 0,16965746 ! myofibril assembly GO:0030239 47 30 0,000 0,14518899 0,1695751 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,14518899 0,16949282 ! phospholipid transport GO:0015914 51 30 0,000 0,14518899 0,16941062 ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,14518899 0,1693285 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,14518899 0,16924646 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,14518899 0,1691645 ! eye morphogenesis GO:0048592 60 30 0,000 0,14518899 0,16908262 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,14964956 0,17419296 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,14964956 0,17410873 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,14964956 0,17402457 ! collagen metabolic process GO:0032963 45 31 0,000 0,14964956 0,1739405 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,14964956 0,17385652 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,14964956 0,17377261 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,14964956 0,17368878 ! ovulation cycle process GO:0022602 49 31 0,000 0,14964956 0,17360504 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,14964956 0,17352137 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,14964956 0,17343779 ! peptide transport GO:0015833 55 31 0,000 0,14964956 0,17335428 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,14964956 0,17327086 ! iron ion homeostasis GO:0055072 54 31 0,000 0,14964956 0,17318752 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,14964956 0,17310425 ! mesoderm formation GO:0001707 69 31 0,000 0,14964956 0,17302107 ! natural killer cell activation GO:0030101 45 31 0,000 0,14964956 0,17293797 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,14964956 0,17285494 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,14964956 0,172772 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,14964956 0,17268913 ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,14964956 0,17260635 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,15408701 0,17763936 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,15408701 0,17755428 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,15408701 0,17746929 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,15408701 0,17738437 ! cholesterol transport GO:0030301 56 32 0,000 0,15408701 0,17729954 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,15408701 0,17721479 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,15408701 0,17713012 ! metanephros development GO:0001656 74 32 0,000 0,15408701 0,17704553 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,15408701 0,17696102 ! response to ionizing radiation GO:0010212 65 32 0,000 0,15408701 0,17687659 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,15408701 0,17679225 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,15408701 0,17670798 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,15408701 0,17662379 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,15408701 0,17653969 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,15408701 0,17645566 ! ovulation cycle GO:0042698 51 32 0,000 0,15408701 0,17637171 ! BMP signaling pathway GO:0030509 64 32 0,000 0,15408701 0,17628785 ! hindbrain development GO:0030902 61 32 0,000 0,15408701 0,17620406 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,15408701 0,17612035 ! gene silencing GO:0016458 65 32 0,000 0,15408701 0,17603672 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,15850145 0,18099406 ! post-embryonic development GO:0009791 69 33 0,000 0,15850145 0,1809082 ! protein targeting to membrane GO:0006612 68 33 0,000 0,15850145 0,18082242 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,15850145 0,18073672 ! ceramide metabolic process GO:0006672 64 33 0,000 0,15850145 0,1806511 ! formation of primary germ layer GO:0001704 72 33 0,000 0,15850145 0,18056557 ! cell fate specification GO:0001708 52 33 0,000 0,15850145 0,18048011 ! sterol transport GO:0015918 57 33 0,000 0,15850145 0,18039474 ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,15850145 0,18030945 ! adult locomotory behavior GO:0008344 59 33 0,000 0,15850145 0,18022423 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,15850145 0,1801391 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,16289299 0,18504275 ! glial cell differentiation GO:0010001 63 34 0,000 0,16289299 0,18495542 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,16289299 0,18486818 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,16289299 0,18478102 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,16289299 0,18469394 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,16289299 0,18460694 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,16289299 0,18452003 ! mismatch repair GO:0006298 46 34 0,000 0,16289299 0,18443319 ! spermatid development GO:0007286 63 34 0,000 0,16289299 0,18434644 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,16289299 0,18425977 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,16289299 0,18417318 ! negative regulation of secretion GO:0051048 63 35 0,000 0,16726176 0,18902386 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,16726176 0,18893512 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,16726176 0,18884646 ! odontogenesis GO:0042476 66 35 0,000 0,16726176 0,18875788 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,16726176 0,18866939 ! female gonad development GO:0008585 58 35 0,000 0,16726176 0,18858098 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,16726176 0,18849265 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,16726176 0,1884044 ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 0,16726176 0,18831624 ! cytokine production GO:0001816 59 35 0,000 0,16726176 0,18822816 ! vesicle localization GO:0051648 64 35 0,000 0,16726176 0,18814016 ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,17160788 0,19293858 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,17160788 0,19284846 ! cell junction organization GO:0034330 86 36 0,000 0,17160788 0,19275843 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,17160788 0,19266849 ! positive regulation of cell development GO:0010720 80 36 0,000 0,17160788 0,19257862 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,17160788 0,19248884 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,17160788 0,19239914 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,17160788 0,19230953 ! aerobic respiration GO:0009060 55 36 0,000 0,17160788 0,19222 ! embryonic organ development GO:0048568 57 36 0,000 0,17160788 0,19213056 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,17160788 0,19204119 ! RNA export from nucleus GO:0006405 56 37 0,000 0,17593146 0,19678805 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,17593146 0,1966966 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,17593146 0,19660525 ! actomyosin structure organization GO:0031032 62 37 0,000 0,17593146 0,19651397 ! organic anion transport GO:0015711 68 37 0,000 0,17593146 0,19642278 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,17593146 0,19633168 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,17593146 0,19624066 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,17593146 0,19614972 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,17593146 0,19605887 GO:0015986|ATP synthesis coupled proton transport, ! pigment metabolic process GO:0042440 80 37 0,000 0,17593146 0,1959681 ! spermatid differentiation GO:0048515 66 37 0,000 0,17593146 0,19587741 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,18023262 0,20057339 GO:0006956|complement activation, ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,18023262 0,20048066 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,18023262 0,20038802 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,18023262 0,20029546 ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,18023262 0,20020299 GO:0046660|female sex differentiation, ! lipid homeostasis GO:0055088 67 38 0,000 0,18023262 0,2001106 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,18023262 0,2000183 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,18023262 0,19992608 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,18023262 0,19983395 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,18023262 0,1997419 ! mRNA catabolic process GO:0006402 71 39 0,000 0,18451146 0,20438977 ! learning GO:0007612 77 39 0,000 0,18451146 0,20429571 ! ear morphogenesis GO:0042471 60 39 0,000 0,18451146 0,20420174 ! organic ether metabolic process GO:0018904 55 39 0,000 0,18451146 0,20410785 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,18451146 0,20401405 ! ion transmembrane transport GO:0034220 66 39 0,000 0,18451146 0,20392034 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,18451146 0,20382671 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,18451146 0,20373317 ! RNA modification GO:0009451 57 39 0,000 0,18451146 0,20363972 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,18451146 0,20354635 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,18876812 0,2081467 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,18876812 0,20805135 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,18876812 0,20795609 ! feeding behavior GO:0007631 59 40 0,000 0,18876812 0,20786091 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,18876812 0,20776583 ! mesenchymal cell development GO:0014031 87 40 0,000 0,18876812 0,20767083 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,18876812 0,20757591 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,1930027 0,21213545 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,1930027 0,21203858 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,1930027 0,2119418 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,1930027 0,21184511 ! gliogenesis GO:0042063 88 41 0,000 0,1930027 0,21174851 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,1930027 0,211652 ! T cell differentiation GO:0030217 81 41 0,000 0,1930027 0,21155558 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,1930027 0,21145924 ! female gamete generation GO:0007292 61 41 0,000 0,1930027 0,21136299 ! polyol metabolic process GO:0019751 66 41 0,000 0,1930027 0,21126683 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,1930027 0,21117076 ! regulation of tube size GO:0035150 71 42 0,000 0,19721531 0,21568184 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,19721531 0,21558384 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,19721531 0,21548594 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,19721531 0,21538813 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,19721531 0,2152904 ! regulation of protein secretion GO:0050708 71 42 0,000 0,19721531 0,21519276 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,19721531 0,21509521 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,20140608 0,21956639 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,20140608 0,21946695 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,20140608 0,21936759 ! striated muscle contraction GO:0006941 77 43 0,000 0,20140608 0,21926833 ! phagocytosis GO:0006909 90 43 0,000 0,20140608 0,21916916 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,20140608 0,21907008 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,2055751 0,2235037 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,2055751 0,22340275 ! male sex differentiation GO:0046661 76 44 0,000 0,2055751 0,22330189 ! double-strand break repair GO:0006302 81 44 0,000 0,2055751 0,22320112 ! B cell differentiation GO:0030183 107 44 0,000 0,2055751 0,22310045 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,2055751 0,22299986 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,2055751 0,22289936 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,2097225 0,22729384 ! glycolysis GO:0006096 65 45 0,000 0,2097225 0,2271915 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,2097225 0,22708926 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,2097225 0,2269871 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,2097225 0,22688504 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,2097225 0,22678307 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,2097225 0,22668119 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,2097225 0,2265794 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,2097225 0,22647771 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,21384838 0,23082961 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,21384838 0,2307261 ! pigmentation GO:0043473 100 46 0,000 0,21384838 0,23062268 ! response to calcium ion GO:0051592 81 47 0,000 0,21795286 0,23494381 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,21795286 0,2348386 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,21795286 0,23473348 ! JNK cascade GO:0007254 91 47 0,000 0,21795286 0,23462845 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,21795286 0,23452352 ! protein homooligomerization GO:0051260 76 47 0,000 0,21795286 0,23441868 ! mitochondrial transport GO:0006839 82 48 0,000 0,22203605 0,23870363 ! Notch signaling pathway GO:0007219 96 48 0,000 0,22203605 0,23859702 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,22203605 0,2384905 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,22203605 0,23838408 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,22203605 0,23827776 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,22609805 0,24252871 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,22609805 0,24242064 ! peptide metabolic process GO:0006518 76 49 0,000 0,22609805 0,24231265 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,22609805 0,24220477 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,22609805 0,24209698 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,22609805 0,24198928 GO:0019724|B cell mediated immunity, ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,22609805 0,24188168 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,23013898 0,24609528 ! neuromuscular process GO:0050905 99 50 0,000 0,23013898 0,24598595 ! regulation of ossification GO:0030278 117 50 0,000 0,23013898 0,24587672 ! inner ear development GO:0048839 79 50 0,000 0,23013898 0,24576759 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,23013898 0,24565855 ! viral infectious cycle GO:0019058 99 51 0,000 0,23415894 0,24983876 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,23415894 0,24972802 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,23415894 0,24961737 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,23415894 0,24950682 ! excretion GO:0007588 83 51 0,000 0,23415894 0,24939637 ! chromatin remodeling GO:0006338 109 51 0,000 0,23415894 0,24928602 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,23415894 0,24917576 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,23415894 0,24906561 ! membrane fusion GO:0006944 110 52 0,000 0,23815804 0,25320736 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,23815804 0,25309552 ! amino acid activation GO:0043038 92 52 0,000 0,23815804 0,25298377 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 76 53 0,000 0,24213639 0,25709628 ! RNA catabolic process GO:0006401 93 53 0,000 0,24213639 0,25698287 ! regulation of translational initiation GO:0006446 82 53 0,000 0,24213639 0,25686956 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,24213639 0,25675635 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,24213639 0,25664324 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,24213639 0,25653024 ! cell maturation GO:0048469 100 53 0,000 0,24213639 0,25641733 ! regulation of neuron apoptosis GO:0043523 100 53 0,000 0,24213639 0,25630452 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,24213639 0,25619181 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,2460941 0,2602648 ! cell recognition GO:0008037 85 54 0,000 0,2460941 0,26015045 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,2460941 0,26003619 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,2460941 0,25992204 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,2460941 0,25980799 ! chloride transport GO:0006821 90 55 0,000 0,25003128 0,2638488 ! glucose catabolic process GO:0006007 82 55 0,000 0,25003128 0,26373312 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,25003128 0,26361755 ! gastrulation GO:0007369 112 55 0,000 0,25003128 0,26350208 ! nuclear export GO:0051168 97 55 0,000 0,25003128 0,26338671 ! regulation of actin filament length GO:0030832 105 56 0,000 0,25394802 0,26739559 ! sensory perception of smell GO:0007608 80 56 0,000 0,25394802 0,26727862 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,25394802 0,26716175 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,25394802 0,26704499 ! proton transport GO:0015992 94 56 0,000 0,25394802 0,26692832 ! hydrogen transport GO:0006818 97 58 0,000 0,26172063 0,27497809 ! regulation of endocytosis GO:0030100 91 58 0,000 0,26172063 0,27485807 ! adult behavior GO:0030534 99 58 0,000 0,26172063 0,27473815 ! positive regulation of secretion GO:0051047 95 59 0,000 0,26557671 0,27866444 ! regulation of cellular component size GO:0032535 109 59 0,000 0,26557671 0,27854296 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,26557671 0,27842159 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,26557671 0,27830033 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,26941277 0,28219727 ! DNA damage response, signal transduction GO:0042770 128 60 0,000 0,26941277 0,28207447 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,26941277 0,28195178 ! camera-type eye development GO:0043010 116 60 0,000 0,26941277 0,28182919 ! kidney development GO:0001822 122 60 0,000 0,26941277 0,28170671 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,27322893 0,2855729 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,27322893 0,28544889 ! tRNA processing GO:0008033 89 61 0,000 0,27322893 0,285325 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,27322893 0,28520122 ! ear development GO:0043583 103 62 0,000 0,27702528 0,28903852 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,27702528 0,28891323 ! gonad development GO:0008406 98 62 0,000 0,27702528 0,28878805 ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,28080192 0,29259828 ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,28080192 0,29247161 ! detection of external stimulus GO:0009581 91 63 0,000 0,28080192 0,29234506 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,28455896 0,2961284 ! cell redox homeostasis GO:0045454 102 64 0,000 0,28455896 0,29600037 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,28455896 0,29587246 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,28455896 0,29574465 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,28455896 0,29561695 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,2882965 0,29937047 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,2882965 0,29924132 ! myeloid cell differentiation GO:0030099 111 65 0,000 0,2882965 0,29911228 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,29201464 0,30283932 ! extracellular matrix organization GO:0030198 133 66 0,000 0,29201464 0,30270884 ! secondary metabolic process GO:0019748 116 66 0,000 0,29201464 0,30257848 ! cell projection assembly GO:0030031 120 66 0,000 0,29201464 0,30244822 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,29571347 0,30614743 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,29571347 0,30601575 ! hexose catabolic process GO:0019320 104 67 0,000 0,29571347 0,30588419 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,29571347 0,30575274 ! activation of immune response GO:0002253 105 67 0,000 0,29571347 0,3056214 ! amino acid transport GO:0006865 125 68 0,000 0,29939311 0,30929146 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,29939311 0,30915872 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,29939311 0,30902609 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,30305364 0,31267026 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,30305364 0,31253624 ! antigen processing and presentation GO:0019882 104 69 0,000 0,30305364 0,31240234 ! humoral immune response GO:0006959 109 71 0,000 0,31031778 0,31975357 ! B cell activation GO:0042113 160 71 0,000 0,31031778 0,31961669 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,31031778 0,31947993 ! regulation of immune effector process GO:0002697 137 71 0,000 0,31031778 0,31934328 ! acute inflammatory response GO:0002526 113 72 0,000 0,31392159 0,32291379 ! learning or memory GO:0007611 147 73 0,000 0,31750669 0,32646201 ! regulation of blood pressure GO:0008217 125 73 0,000 0,31750669 0,32632256 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,31750669 0,32618322 ! fertilization GO:0009566 90 73 0,000 0,31750669 0,32604401 ! transition metal ion transport GO:0000041 126 74 0,000 0,32107318 0,32956573 ! neurotransmitter transport GO:0006836 123 74 0,000 0,32107318 0,32942519 ! exocytosis GO:0006887 133 74 0,000 0,32107318 0,32928477 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,32107318 0,32914447 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,32107318 0,32900429 ! eye development GO:0001654 143 74 0,000 0,32107318 0,32886423 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,32462114 0,3323568 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,32462114 0,33221543 ! rhythmic process GO:0048511 128 75 0,000 0,32462114 0,33207418 ! lymphocyte differentiation GO:0030098 167 75 0,000 0,32462114 0,33193305 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,32815068 0,33539955 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,32815068 0,33525713 ! defense response to bacterium GO:0042742 89 76 0,000 0,32815068 0,33511483 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,32815068 0,33497265 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,32815068 0,3348306 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,3316619 0,33826983 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,3316619 0,33812649 ! blood coagulation GO:0007596 146 78 0,000 0,33515488 0,34154283 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,33515488 0,34139824 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,33862971 0,34479183 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,33862971 0,34464598 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,33862971 0,34450025 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,34208651 0,34786988 ! inorganic anion transport GO:0015698 138 80 0,000 0,34208651 0,34772291 ! T cell activation GO:0042110 168 81 0,000 0,34552535 0,35107009 ! digestion GO:0007586 112 81 0,000 0,34552535 0,3509219 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,34552535 0,35077383 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,34894633 0,35409737 ! response to nutrient GO:0007584 125 82 0,000 0,34894633 0,35394809 ! hemostasis GO:0007599 158 84 0,000 0,35573507 0,36068208 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,35573507 0,36053015 ! response to unfolded protein GO:0006986 131 85 0,000 0,35910302 0,36379026 ! nucleosome assembly GO:0006334 122 85 0,000 0,35910302 0,36363715 ! amine biosynthetic process GO:0009309 138 86 0,000 0,36245347 0,3668755 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,36245347 0,36672122 ! chromatin assembly GO:0031497 124 86 0,000 0,36245347 0,36656707 ! alcohol catabolic process GO:0046164 130 86 0,000 0,36245347 0,36641305 ! amine transport GO:0015837 155 86 0,000 0,36245347 0,36625916 ! cellular respiration GO:0045333 135 88 0,000 0,36910226 0,37282117 ! regulation of neurological system process GO:0031644 148 88 0,000 0,36910226 0,37266472 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,36910226 0,3725084 ! cellular defense response GO:0006968 114 89 0,000 0,37240077 0,37567977 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,37568214 0,37883119 ! sterol metabolic process GO:0016125 152 91 0,000 0,37894646 0,3819628 ! response to protein stimulus GO:0051789 149 91 0,000 0,37894646 0,38180285 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,37894646 0,38164303 ! nucleosome organization GO:0034728 138 92 0,000 0,38219383 0,38475245 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,38219383 0,38459153 ! vitamin metabolic process GO:0006766 139 92 0,000 0,38219383 0,38443075 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,38863803 0,39074931 ! female pregnancy GO:0007565 164 94 0,000 0,38863803 0,39058609 ! transcription initiation GO:0006352 153 94 0,000 0,38863803 0,39042301 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,39183504 0,39347041 ! leukocyte differentiation GO:0002521 202 96 0,000 0,39501544 0,3964986 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,39501544 0,39633326 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,39501544 0,39616805 ! positive regulation of immune response GO:0050778 156 96 0,000 0,39501544 0,39600298 ! detection of stimulus GO:0051606 151 96 0,000 0,39501544 0,39583805 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,39817931 0,39884239 ! hormone metabolic process GO:0042445 157 97 0,000 0,39817931 0,39867641 ! response to virus GO:0009615 160 98 0,000 0,40132674 0,40166062 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,40132674 0,40149361 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,40445781 0,40445781