pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6641-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! G1/S transition of mitotic cell cycle GO:0000082 124 46 6,000 1,879E-09 4,59E-06 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 7,000 3,585E-09 4,379E-06 ! regulation of ligase activity GO:0051340 147 84 7,000 5,874E-09 4,783E-06 ! interphase of mitotic cell cycle GO:0051329 224 98 7,000 2,007E-08 1,226E-05 ! induction of positive chemotaxis GO:0050930 17 9 3,000 5,54E-08 2,707E-05 ! negative regulation of phosphorylation GO:0042326 52 24 4,000 8,028E-08 3,269E-05 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 4,000 1,233E-07 4,303E-05 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of positive chemotaxis GO:0050926 22 12 3,000 2,153E-07 6,575E-05 GO:0050927|positive regulation of positive chemotaxis, ! negative regulation of ligase activity GO:0051352 116 68 5,000 7,88E-07 2,139E-04 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 5,000 8,597E-07 2,1E-04 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 5,000 1,108E-06 2,46E-04 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 5,000 1,108E-06 2,255E-04 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 3,000 1,302E-06 2,447E-04 ! positive regulation of ligase activity GO:0051351 130 77 5,000 1,649E-06 2,878E-04 ! induction of apoptosis by intracellular signals GO:0008629 95 45 4,000 2,133E-06 3,474E-04 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 3,000 2,52E-06 3,847E-04 ! positive regulation of locomotion GO:0040017 44 22 3,000 3,068E-06 4,409E-04 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 2,000 3,391E-06 4,603E-04 ! embryonic heart tube development GO:0035050 14 7 2,000 3,391E-06 4,361E-04 ! regulation of chemotaxis GO:0050920 45 23 3,000 3,701E-06 4,521E-04 ! regulation of cell cycle process GO:0010564 161 90 5,000 4,12E-06 4,793E-04 ! regulation of behavior GO:0050795 48 25 3,000 5,249E-06 5,829E-04 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 2,000 5,408E-06 5,744E-04 ! regulation of T cell differentiation in the thymus GO:0033081 14 8 2,000 5,408E-06 5,505E-04 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 2,000 5,408E-06 5,284E-04 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 4,000 6,988E-06 6,566E-04 ! insulin receptor signaling pathway GO:0008286 66 27 3,000 7,229E-06 6,541E-04 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 2,000 8,084E-06 7,053E-04 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 3,000 9,713E-06 8,183E-04 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 2,000 1,151E-05 9,372E-04 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 2,000 1,151E-05 9,07E-04 ! protein amino acid autophosphorylation GO:0046777 157 64 4,000 1,24E-05 9,464E-04 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 4,000 1,553E-05 1,149E-03 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 2,000 1,577E-05 1,133E-03 ! chondrocyte differentiation GO:0002062 27 11 2,000 1,577E-05 1,101E-03 ! negative regulation of glucose import GO:0046325 18 11 2,000 1,577E-05 1,07E-03 GO:0010829|negative regulation of glucose transport, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 4,000 1,67E-05 1,102E-03 ! negative regulation of protein kinase activity GO:0006469 144 69 4,000 1,793E-05 1,153E-03 ! negative regulation of kinase activity GO:0033673 145 70 4,000 1,924E-05 1,205E-03 ! positive regulation of cellular catabolic process GO:0031331 34 12 2,000 2,096E-05 1,28E-03 ! regulation of B cell proliferation GO:0030888 22 12 2,000 2,096E-05 1,249E-03 ! negative regulation of mast cell proliferation GO:0070667 24 12 2,000 2,096E-05 1,219E-03 GO:0042130|negative regulation of T cell proliferation, ! negative regulation of transferase activity GO:0051348 155 74 4,000 2,523E-05 1,433E-03 ! regulation of monooxygenase activity GO:0032768 35 13 2,000 2,715E-05 1,507E-03 ! cellular response to insulin stimulus GO:0032869 85 38 3,000 2,922E-05 1,586E-03 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 2,000 3,444E-05 1,829E-03 ! regulation of the force of heart contraction GO:0002026 31 15 2,000 4,29E-05 2,23E-03 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 2,000 4,29E-05 2,183E-03 ! positive regulation of response to external stimulus GO:0032103 88 44 3,000 5,259E-05 2,622E-03 ! negative regulation of leukocyte proliferation GO:0070664 32 16 2,000 5,262E-05 2,571E-03 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! regulation of gene-specific transcription GO:0032583 102 46 3,000 6,276E-05 3,006E-03 ! embryonic forelimb morphogenesis GO:0035115 31 17 2,000 6,368E-05 2,992E-03 ! regulation of survival gene product expression GO:0045884 38 17 2,000 6,368E-05 2,935E-03 ! neutrophil chemotaxis GO:0030593 29 17 2,000 6,368E-05 2,881E-03 ! response to insulin stimulus GO:0032868 98 47 3,000 6,835E-05 3,036E-03 ! positive regulation of cell cycle GO:0045787 96 48 3,000 7,429E-05 3,241E-03 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 4,000 7,582E-05 3,25E-03 GO:0010498|proteasomal protein catabolic process, ! regulation of mast cell proliferation GO:0070666 89 49 3,000 8,061E-05 3,395E-03 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 2,000 1,057E-04 4,375E-03 ! forelimb morphogenesis GO:0035136 35 20 2,000 1,057E-04 4,302E-03 ! apoptotic mitochondrial changes GO:0008637 42 20 2,000 1,057E-04 4,232E-03 ! peptidyl-serine phosphorylation GO:0018105 44 20 2,000 1,057E-04 4,163E-03 ! regulation of glucose import GO:0046324 30 20 2,000 1,057E-04 4,097E-03 GO:0010827|regulation of glucose transport, ! negative regulation of T cell activation GO:0050868 41 20 2,000 1,057E-04 4,033E-03 ! regulation of leukocyte proliferation GO:0070663 97 53 3,000 1,098E-04 4,127E-03 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! cartilage development GO:0051216 99 53 3,000 1,098E-04 4,064E-03 ! regulation of muscle contraction GO:0006937 94 54 3,000 1,182E-04 4,309E-03 ! positive regulation of inflammatory response GO:0050729 41 21 2,000 1,229E-04 4,414E-03 ! response to UV GO:0009411 120 55 3,000 1,27E-04 4,496E-03 ! inactivation of MAPK activity GO:0000188 45 22 2,000 1,418E-04 4,948E-03 ! apoptotic nuclear changes GO:0030262 34 22 2,000 1,418E-04 4,878E-03 ! positive regulation of intracellular transport GO:0032388 42 22 2,000 1,418E-04 4,81E-03 ! peptidyl-serine modification GO:0018209 50 22 2,000 1,418E-04 4,744E-03 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 2,000 1,418E-04 4,68E-03 ! positive regulation of cell migration GO:0030335 137 58 3,000 1,563E-04 5,09E-03 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 2,000 1,625E-04 5,223E-03 ! regulation of cellular catabolic process GO:0031329 55 24 2,000 1,851E-04 5,871E-03 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 2,000 1,851E-04 5,796E-03 ! regulation of oxidoreductase activity GO:0051341 48 24 2,000 1,851E-04 5,723E-03 ! regulation of heart contraction GO:0008016 123 61 3,000 1,901E-04 5,806E-03 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 2,000 2,096E-04 6,321E-03 ! vasculogenesis GO:0001570 49 25 2,000 2,096E-04 6,244E-03 ! negative regulation of bone resorption GO:0045779 10 5 1,000 2,122E-04 6,247E-03 ! tongue development GO:0043586 8 5 1,000 2,122E-04 6,173E-03 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 1,000 2,122E-04 6,1E-03 ! positive regulation of glycolysis GO:0045821 13 5 1,000 2,122E-04 6,029E-03 ! anagen GO:0042640 7 5 1,000 2,122E-04 5,96E-03 ! positive regulation of viral genome replication GO:0045070 9 5 1,000 2,122E-04 5,892E-03 ! regulation of cardiac muscle contraction GO:0055117 6 5 1,000 2,122E-04 5,826E-03 ! response to food GO:0032094 6 5 1,000 2,122E-04 5,761E-03 ! positive regulation of transporter activity GO:0032411 8 5 1,000 2,122E-04 5,698E-03 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of phospholipase A2 activity GO:0032429 15 5 1,000 2,122E-04 5,636E-03 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 1,000 2,122E-04 5,575E-03 ! meiotic chromosome segregation GO:0045132 10 5 1,000 2,122E-04 5,516E-03 ! response to mercury ion GO:0046689 8 5 1,000 2,122E-04 5,458E-03 ! regulation of muscle cell apoptosis GO:0010660 7 5 1,000 2,122E-04 5,401E-03 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 1,000 2,122E-04 5,345E-03 ! protein insertion into membrane GO:0051205 17 5 1,000 2,122E-04 5,291E-03 ! stem cell division GO:0017145 11 5 1,000 2,122E-04 5,237E-03 GO:0048103|somatic stem cell division, ! regulation of mitosis GO:0007088 112 63 3,000 2,155E-04 5,264E-03 GO:0051783|regulation of nuclear division, ! response to peptide hormone stimulus GO:0043434 129 64 3,000 2,29E-04 5,539E-03 ! positive regulation of cell motion GO:0051272 157 65 3,000 2,431E-04 5,823E-03 ! negative regulation of lymphocyte activation GO:0051250 55 27 2,000 2,647E-04 6,279E-03 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 2,000 2,955E-04 6,941E-03 ! negative regulation of protein modification process GO:0031400 66 28 2,000 2,955E-04 6,875E-03 ! negative regulation of cell size GO:0045792 144 69 3,000 3,06E-04 7,053E-03 ! lung development GO:0030324 165 69 3,000 3,06E-04 6,987E-03 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 3,000 3,06E-04 6,922E-03 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 1,000 3,174E-04 7,113E-03 ! regulation of retroviral genome replication GO:0045091 8 6 1,000 3,174E-04 7,049E-03 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 1,000 3,174E-04 6,985E-03 ! early endosome to late endosome transport GO:0045022 16 6 1,000 3,174E-04 6,923E-03 ! establishment of spindle localization GO:0051293 16 6 1,000 3,174E-04 6,862E-03 GO:0051653|spindle localization, ! hair follicle maturation GO:0048820 8 6 1,000 3,174E-04 6,801E-03 ! negative regulation of B cell activation GO:0050869 14 6 1,000 3,174E-04 6,742E-03 ! respiratory tube development GO:0030323 171 72 3,000 3,603E-04 7,587E-03 ! negative regulation of transcription regulator activity GO:0090048 57 30 2,000 3,637E-04 7,594E-03 GO:0043433|negative regulation of transcription factor activity, ! regulation of B cell activation GO:0050864 55 30 2,000 3,637E-04 7,53E-03 ! respiratory system development GO:0060541 175 74 3,000 4E-04 8,212E-03 ! cellular response to extracellular stimulus GO:0031668 52 31 2,000 4,013E-04 8,17E-03 ! negative regulation of leukocyte activation GO:0002695 60 31 2,000 4,013E-04 8,102E-03 ! regulation of transcription factor activity GO:0051090 137 75 3,000 4,211E-04 8,431E-03 GO:0090046|regulation of transcription regulator activity, ! positive regulation of catabolic process GO:0009896 72 32 2,000 4,413E-04 8,765E-03 ! prostate gland development GO:0030850 14 7 1,000 4,43E-04 8,727E-03 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 4,43E-04 8,658E-03 ! N-terminal protein amino acid acetylation GO:0006474 14 7 1,000 4,43E-04 8,589E-03 ! mRNA stabilization GO:0048255 18 7 1,000 4,43E-04 8,521E-03 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 1,000 4,43E-04 8,455E-03 ! male sex determination GO:0030238 15 7 1,000 4,43E-04 8,389E-03 ! positive regulation of monooxygenase activity GO:0032770 12 7 1,000 4,43E-04 8,325E-03 ! regulation of meiosis GO:0040020 12 7 1,000 4,43E-04 8,261E-03 GO:0051445|regulation of meiotic cell cycle, ! anaphase GO:0051322 18 7 1,000 4,43E-04 8,198E-03 GO:0000090|mitotic anaphase, ! regulation of catabolic process GO:0009894 173 77 3,000 4,654E-04 8,549E-03 ! positive regulation of gene-specific transcription GO:0043193 70 33 2,000 4,838E-04 8,82E-03 ! leukocyte chemotaxis GO:0030595 55 33 2,000 4,838E-04 8,755E-03 GO:0060326|cell chemotaxis, ! negative regulation of MAP kinase activity GO:0043407 78 34 2,000 5,288E-04 9,499E-03 ! positive regulation of phosphorylation GO:0042327 149 81 3,000 5,641E-04 0,01005826 ! T-helper 1 type immune response GO:0042088 12 8 1,000 5,888E-04 0,01042409 ! L-phenylalanine metabolic process GO:0006558 12 8 1,000 5,888E-04 0,01034909 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 13 8 1,000 5,888E-04 0,01027517 ! positive regulation of endothelial cell migration GO:0010595 19 8 1,000 5,888E-04 0,0102023 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 1,000 5,888E-04 0,01013045 ! regulation of vascular permeability GO:0043114 12 8 1,000 5,888E-04 0,01005961 ! cardiac muscle cell differentiation GO:0055007 31 8 1,000 5,888E-04 9,99E-03 ! cardiac muscle cell development GO:0055013 14 8 1,000 5,888E-04 9,921E-03 ! DNA topological change GO:0006265 12 8 1,000 5,888E-04 9,853E-03 ! regulation of respiratory burst GO:0060263 12 8 1,000 5,888E-04 9,786E-03 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 1,000 5,888E-04 9,72E-03 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 3,000 6,185E-04 0,0101416 GO:0045937|positive regulation of phosphate metabolic process, ! negative regulation of DNA binding GO:0043392 67 36 2,000 6,267E-04 0,01020632 ! negative regulation of transport GO:0051051 164 85 3,000 6,767E-04 0,0109476 ! cellular response to hormone stimulus GO:0032870 182 85 3,000 6,767E-04 0,01087558 ! androgen receptor signaling pathway GO:0030521 81 37 2,000 6,796E-04 0,01085213 ! negative regulation of cell activation GO:0050866 69 37 2,000 6,796E-04 0,01078166 ! regulation of protein stability GO:0031647 77 38 2,000 7,354E-04 0,01159081 ! glycogen metabolic process GO:0005977 63 38 2,000 7,354E-04 0,01151651 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 7,548E-04 0,01174451 ! regulation of glycolysis GO:0006110 20 9 1,000 7,548E-04 0,01167018 ! microtubule bundle formation GO:0001578 22 9 1,000 7,548E-04 0,01159678 ! receptor clustering GO:0043113 20 9 1,000 7,548E-04 0,0115243 ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 1,000 7,548E-04 0,01145272 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 1,000 7,548E-04 0,01138203 ! negative regulation of binding GO:0051100 71 39 2,000 7,94E-04 0,01189991 ! glucan metabolic process GO:0044042 64 39 2,000 7,94E-04 0,01182735 GO:0006073|cellular glucan metabolic process, ! regulation of DNA binding GO:0051101 167 89 3,000 8,043E-04 0,01190899 ! nucleus organization GO:0006997 73 40 2,000 8,554E-04 0,01258941 ! gland development GO:0048732 220 91 3,000 8,741E-04 0,01278766 ! lung alveolus development GO:0048286 26 10 1,000 9,406E-04 0,01367757 ! negative regulation of striated muscle development GO:0045843 26 10 1,000 9,406E-04 0,01359663 ! positive regulation of survival gene product expression GO:0045885 26 10 1,000 9,406E-04 0,01351665 ! glucan biosynthetic process GO:0009250 14 10 1,000 9,406E-04 0,01343761 GO:0005978|glycogen biosynthetic process, ! regulation of sodium ion transport GO:0002028 26 10 1,000 9,406E-04 0,01335948 ! motor axon guidance GO:0008045 22 10 1,000 9,406E-04 0,01328226 ! protein heterooligomerization GO:0051291 17 10 1,000 9,406E-04 0,01320593 ! regulation of developmental growth GO:0048638 16 10 1,000 9,406E-04 0,01313046 ! autophagic vacuole formation GO:0000045 17 10 1,000 9,406E-04 0,01305586 ! positive regulation of B cell proliferation GO:0030890 18 10 1,000 9,406E-04 0,0129821 ! regulation of bone resorption GO:0045124 25 10 1,000 9,406E-04 0,01290916 ! DNA ligation GO:0006266 18 10 1,000 9,406E-04 0,01283705 ! positive regulation of viral reproduction GO:0048524 19 10 1,000 9,406E-04 0,01276573 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 1,000 9,406E-04 0,0126952 GO:0043470|regulation of carbohydrate catabolic process, ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 1,000 9,406E-04 0,01262545 ! positive regulation of MAP kinase activity GO:0043406 174 93 3,000 9,481E-04 0,01265721 ! regulation of intracellular protein transport GO:0033157 86 42 2,000 9,872E-04 0,01310779 ! regulation of T cell differentiation GO:0045580 78 42 2,000 9,872E-04 0,01303694 ! regulation of T cell proliferation GO:0042129 80 43 2,000 1,058E-03 0,0138921 ! neuron migration GO:0001764 85 43 2,000 1,058E-03 0,01381781 ! energy reserve metabolic process GO:0006112 76 44 2,000 1,131E-03 0,01469999 ! negative regulation of muscle development GO:0048635 27 11 1,000 1,146E-03 0,01481428 ! thyroid gland development GO:0030878 26 11 1,000 1,146E-03 0,01473631 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 1,000 1,146E-03 0,01465915 ! blood vessel remodeling GO:0001974 30 11 1,000 1,146E-03 0,0145828 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 1,000 1,146E-03 0,01450725 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 23 11 1,000 1,146E-03 0,01443247 ! peptide or protein amino-terminal blocking GO:0018409 22 11 1,000 1,146E-03 0,01435845 ! adult heart development GO:0007512 16 11 1,000 1,146E-03 0,0142852 ! macroautophagy GO:0016236 19 11 1,000 1,146E-03 0,01421268 ! DNA methylation GO:0006306 19 11 1,000 1,146E-03 0,0141409 GO:0006305|DNA alkylation, ! positive regulation of neuron differentiation GO:0045666 22 11 1,000 1,146E-03 0,01406984 ! positive regulation of leukocyte migration GO:0002687 28 11 1,000 1,146E-03 0,01399949 ! cardiac cell differentiation GO:0035051 36 11 1,000 1,146E-03 0,01392984 ! regulation of embryonic development GO:0045995 35 11 1,000 1,146E-03 0,01386088 ! regulation of epithelial cell proliferation GO:0050678 122 45 2,000 1,208E-03 0,01453676 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 2,000 1,288E-03 0,01542229 ! leukocyte migration GO:0050900 75 46 2,000 1,288E-03 0,01534706 ! cell growth GO:0016049 90 46 2,000 1,288E-03 0,01527256 ! positive regulation of protein transport GO:0051222 80 46 2,000 1,288E-03 0,01519878 ! virus-host interaction GO:0019048 30 12 1,000 1,371E-03 0,01610404 ! dopamine receptor signaling pathway GO:0007212 28 12 1,000 1,371E-03 0,01602698 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 1,000 1,371E-03 0,01595066 ! tyrosine metabolic process GO:0006570 19 12 1,000 1,371E-03 0,01587507 ! histone acetylation GO:0016573 27 12 1,000 1,371E-03 0,01580019 ! peptidyl-lysine modification GO:0018205 21 12 1,000 1,371E-03 0,01572601 ! T cell homeostasis GO:0043029 28 12 1,000 1,371E-03 0,01565252 ! regulation of leukocyte migration GO:0002685 29 12 1,000 1,371E-03 0,01557972 ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 1,000 1,371E-03 0,01550759 ! localization within membrane GO:0051668 26 12 1,000 1,371E-03 0,01543613 ! positive regulation of defense response GO:0031349 88 48 2,000 1,457E-03 0,01633238 ! regulation of inflammatory response GO:0050727 84 48 2,000 1,457E-03 0,0162578 ! regulation of lymphocyte differentiation GO:0045619 92 49 2,000 1,547E-03 0,017181 ! cartilage condensation GO:0001502 22 13 1,000 1,615E-03 0,01785794 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 1,000 1,615E-03 0,0177775 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! aromatic amino acid family catabolic process GO:0009074 20 13 1,000 1,615E-03 0,01769778 ! spleen development GO:0048536 24 13 1,000 1,615E-03 0,01761877 ! regulation of mRNA stability GO:0043488 32 13 1,000 1,615E-03 0,01754047 ! cytoplasmic sequestering of protein GO:0051220 25 13 1,000 1,615E-03 0,01746286 ! induction of apoptosis by extracellular signals GO:0008624 99 50 2,000 1,64E-03 0,01765406 ! negative regulation of immune system process GO:0002683 101 51 2,000 1,737E-03 0,01861196 ! regulation of RNA stability GO:0043487 33 14 1,000 1,879E-03 0,0200452 ! positive regulation of growth GO:0045927 96 53 2,000 1,941E-03 0,02061428 ! N-terminal protein amino acid modification GO:0031365 30 15 1,000 2,161E-03 0,02285903 ! negative regulation of bone remodeling GO:0046851 34 15 1,000 2,161E-03 0,0227605 ! actin cytoskeleton reorganization GO:0031532 38 15 1,000 2,161E-03 0,02266282 ! positive regulation of oxidoreductase activity GO:0051353 22 15 1,000 2,161E-03 0,02256597 ! lymphocyte homeostasis GO:0002260 33 15 1,000 2,161E-03 0,02246994 ! positive regulation of calcium ion transport GO:0051928 21 15 1,000 2,161E-03 0,02237473 ! regulation of protein catabolic process GO:0042176 126 56 2,000 2,273E-03 0,02343307 ! heart morphogenesis GO:0003007 105 57 2,000 2,391E-03 0,02454772 ! regulation of intracellular transport GO:0032386 108 57 2,000 2,391E-03 0,02444501 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 2,463E-03 0,02506842 ! positive regulation of ion transport GO:0043270 23 16 1,000 2,463E-03 0,0249644 ! regulation of transmembrane transporter activity GO:0022898 27 16 1,000 2,463E-03 0,02486124 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! positive regulation of protein import into nucleus GO:0042307 34 16 1,000 2,463E-03 0,02475893 ! negative regulation of tissue remodeling GO:0034104 37 16 1,000 2,463E-03 0,02465746 ! cellular polysaccharide metabolic process GO:0044264 93 58 2,000 2,513E-03 0,02506208 ! negative regulation of cell cycle process GO:0010948 35 17 1,000 2,783E-03 0,02763362 ! signal complex assembly GO:0007172 47 17 1,000 2,783E-03 0,02752174 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 1,000 2,783E-03 0,02741076 ! cardiac muscle tissue development GO:0048738 34 17 1,000 2,783E-03 0,02730068 ! regulation of striated muscle contraction GO:0006942 23 17 1,000 2,783E-03 0,02719148 ! negative regulation of microtubule depolymerization GO:0007026 50 17 1,000 2,783E-03 0,02708315 GO:0031114|regulation of microtubule depolymerization, ! DNA fragmentation involved in apoptosis GO:0006309 27 17 1,000 2,783E-03 0,02697567 ! negative regulation of homeostatic process GO:0032845 36 17 1,000 2,783E-03 0,02686905 ! negative regulation of response to stimulus GO:0048585 106 61 2,000 2,902E-03 0,0279115 ! heart looping GO:0001947 34 18 1,000 3,121E-03 0,02989941 ! regulation of viral genome replication GO:0045069 30 18 1,000 3,121E-03 0,02978261 ! positive regulation of proteolysis GO:0045862 36 18 1,000 3,121E-03 0,02966673 ! negative regulation of protein catabolic process GO:0042177 42 18 1,000 3,121E-03 0,02955174 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 1,000 3,121E-03 0,02943764 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 1,000 3,121E-03 0,02932442 ! neuromuscular junction development GO:0007528 43 19 1,000 3,477E-03 0,03254954 ! regulation of endothelial cell migration GO:0010594 45 19 1,000 3,477E-03 0,0324253 ! steroid hormone receptor signaling pathway GO:0030518 146 66 2,000 3,628E-03 0,03369954 ! negative regulation of cell growth GO:0030308 142 67 2,000 3,785E-03 0,03502703 ! embryonic limb morphogenesis GO:0030326 139 67 2,000 3,785E-03 0,03489485 GO:0035113|embryonic appendage morphogenesis, ! chromosome segregation GO:0007059 127 67 2,000 3,785E-03 0,03476367 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 1,000 3,852E-03 0,03524601 ! phosphoinositide phosphorylation GO:0046854 40 20 1,000 3,852E-03 0,0351145 ! protein amino acid acetylation GO:0006473 41 20 1,000 3,852E-03 0,03498396 ! regulation of carbohydrate metabolic process GO:0006109 37 20 1,000 3,852E-03 0,03485439 GO:0010675|regulation of cellular carbohydrate metabolic process, ! aromatic compound catabolic process GO:0019439 31 20 1,000 3,852E-03 0,03472578 ! lipid phosphorylation GO:0046834 43 21 1,000 4,245E-03 0,03812387 ! cell structure disassembly during apoptosis GO:0006921 32 21 1,000 4,245E-03 0,03798422 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 2,000 4,455E-03 0,03972503 ! appendage morphogenesis GO:0035107 150 72 2,000 4,633E-03 0,04116232 GO:0035108|limb morphogenesis, ! positive regulation of protein catabolic process GO:0045732 44 22 1,000 4,655E-03 0,041203 ! hindlimb morphogenesis GO:0035137 47 22 1,000 4,655E-03 0,04105425 ! cellular response to starvation GO:0009267 37 22 1,000 4,655E-03 0,04090657 ! response to glucocorticoid stimulus GO:0051384 42 22 1,000 4,655E-03 0,04075995 ! positive regulation of B cell activation GO:0050871 42 22 1,000 4,655E-03 0,04061438 ! protein stabilization GO:0050821 41 22 1,000 4,655E-03 0,04046985 ! appendage development GO:0048736 151 73 2,000 4,816E-03 0,04171987 GO:0060173|limb development, ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 2,000 5,002E-03 0,04318311 ! positive regulation of DNA replication GO:0045740 44 23 1,000 5,083E-03 0,0437228 ! regulation of cell-matrix adhesion GO:0001952 81 23 1,000 5,083E-03 0,04356939 GO:0010810|regulation of cell-substrate adhesion, ! activation of pro-apoptotic gene products GO:0008633 51 23 1,000 5,083E-03 0,04341705 ! cellular response to reactive oxygen species GO:0034614 35 23 1,000 5,083E-03 0,04326577 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 1,000 5,083E-03 0,04311554 GO:0060415|muscle tissue morphogenesis, ! DNA modification GO:0006304 36 23 1,000 5,083E-03 0,04296635 ! phosphoinositide-mediated signaling GO:0048015 141 75 2,000 5,193E-03 0,04374883 ! positive regulation of cell adhesion GO:0045785 61 24 1,000 5,528E-03 0,046409 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 1,000 5,528E-03 0,04625007 ! response to corticosteroid stimulus GO:0031960 46 24 1,000 5,528E-03 0,04609222 ! sex determination GO:0007530 48 24 1,000 5,528E-03 0,04593544 ! regulation of viral reproduction GO:0050792 41 24 1,000 5,528E-03 0,04577973 ! aromatic amino acid family metabolic process GO:0009072 37 24 1,000 5,528E-03 0,04562507 ! negative regulation of catabolic process GO:0009895 52 24 1,000 5,528E-03 0,04547145 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 1,000 5,528E-03 0,04531886 ! protein import into nucleus, translocation GO:0000060 51 25 1,000 5,991E-03 0,04894598 ! positive regulation of fibroblast proliferation GO:0048146 48 25 1,000 5,991E-03 0,04878283 ! regulation of transmembrane transport GO:0034762 39 25 1,000 5,991E-03 0,04862076 ! receptor metabolic process GO:0043112 53 25 1,000 5,991E-03 0,04845976 ! chromosome condensation GO:0030261 48 25 1,000 5,991E-03 0,04829983 ! interaction with host GO:0051701 66 25 1,000 5,991E-03 0,04814095 ! leukocyte homeostasis GO:0001776 50 25 1,000 5,991E-03 0,04798311 ! protein tetramerization GO:0051262 57 25 1,000 5,991E-03 0,0478263 ! negative regulation of organelle organization GO:0010639 181 80 2,000 6,213E-03 0,04944285 ! response to hypoxia GO:0001666 178 81 2,000 6,431E-03 0,05100572 ! myelination GO:0042552 50 26 1,000 6,47E-03 0,05115325 ! molting cycle process GO:0022404 52 26 1,000 6,47E-03 0,05098824 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! regulation of transcription factor import into nucleus GO:0042990 58 26 1,000 6,47E-03 0,05082429 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 1,000 6,47E-03 0,05066139 ! response to endoplasmic reticulum stress GO:0034976 46 26 1,000 6,47E-03 0,05049953 ! positive regulation of nuclear division GO:0051785 41 26 1,000 6,47E-03 0,0503387 GO:0045840|positive regulation of mitosis, ! neural tube closure GO:0001843 58 26 1,000 6,47E-03 0,0501789 GO:0060606|tube closure, ! response to oxygen levels GO:0070482 183 83 2,000 6,879E-03 0,05317813 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 1,000 6,966E-03 0,0536881 ! tube lumen formation GO:0035148 59 27 1,000 6,966E-03 0,05351926 ! regulation of endothelial cell proliferation GO:0001936 60 27 1,000 6,966E-03 0,05335149 ! response to starvation GO:0042594 47 27 1,000 6,966E-03 0,05318477 ! cellular response to oxidative stress GO:0034599 43 27 1,000 6,966E-03 0,05301908 ! regulation of chromosome organization GO:0033044 49 27 1,000 6,966E-03 0,05285443 ! cellular response to nutrient levels GO:0031669 45 27 1,000 6,966E-03 0,05269079 ! negative regulation of growth GO:0045926 168 85 2,000 7,345E-03 0,0553798 ! regulation of fibroblast proliferation GO:0048145 56 28 1,000 7,48E-03 0,05622389 ! protein amino acid acylation GO:0043543 59 28 1,000 7,48E-03 0,05605143 ! dendrite development GO:0016358 67 28 1,000 7,48E-03 0,05588001 ! peptidyl-tyrosine modification GO:0018212 57 28 1,000 7,48E-03 0,05570965 ! regulation of protein transport GO:0051223 165 87 2,000 7,829E-03 0,05813518 GO:0070201|regulation of establishment of protein localization, ! mitochondrion organization GO:0007005 159 87 2,000 7,829E-03 0,05795902 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 1,000 8,009E-03 0,0591144 ! ER-nuclear signaling pathway GO:0006984 52 29 1,000 8,009E-03 0,05893635 ! autophagy GO:0006914 47 29 1,000 8,009E-03 0,05875936 ! primary neural tube formation GO:0014020 61 29 1,000 8,009E-03 0,05858344 ! response to organic cyclic substance GO:0014070 58 29 1,000 8,009E-03 0,05840856 ! somitogenesis GO:0001756 52 29 1,000 8,009E-03 0,05823472 ! determination of left/right symmetry GO:0007368 53 30 1,000 8,555E-03 0,06202088 ! positive regulation of multicellular organism growth GO:0040018 55 30 1,000 8,555E-03 0,06183739 ! positive regulation of protein modification process GO:0031401 156 90 2,000 8,59E-03 0,06190613 ! ossification GO:0001503 205 91 2,000 8,853E-03 0,06361416 ! determination of bilateral symmetry GO:0009855 55 31 1,000 9,118E-03 0,06532222 GO:0009799|determination of symmetry, ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 1,000 9,118E-03 0,06513122 ! ensheathment of neurons GO:0007272 64 31 1,000 9,118E-03 0,06494133 GO:0008366|axon ensheathment, ! response to heat GO:0009408 54 31 1,000 9,118E-03 0,06475255 ! bone development GO:0060348 206 92 2,000 9,121E-03 0,06458808 ! regulation of cell adhesion GO:0030155 241 92 2,000 9,121E-03 0,06440141 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 1,000 9,696E-03 0,06826512 ! spindle organization GO:0007051 50 32 1,000 9,696E-03 0,06806895 ! regulation of protein import into nucleus GO:0042306 69 32 1,000 9,696E-03 0,06787391 ! muscle cell development GO:0055001 52 32 1,000 9,696E-03 0,06767999 ! peripheral nervous system development GO:0007422 68 32 1,000 9,696E-03 0,06748717 ! regulation of defense response GO:0031347 171 95 2,000 9,953E-03 0,06907428 ! negative regulation of multicellular organismal process GO:0051241 174 95 2,000 9,953E-03 0,0688786 ! regulation of T cell activation GO:0050863 175 96 2,000 0,0102392 0,07066207 ! regulation of calcium ion transport GO:0051924 60 33 1,000 0,01029063 0,07081691 ! negative regulation of protein transport GO:0051224 74 33 1,000 0,01029063 0,07061799 ! regulation of protein localization GO:0032880 188 97 2,000 0,01053059 0,07206227 ! spliceosome assembly GO:0000245 75 34 1,000 0,01090074 0,07438691 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 1,000 0,01090074 0,07417971 ! skeletal muscle tissue development GO:0007519 223 100 2,000 0,01143345 0,07758865 GO:0060538|skeletal muscle organ development, ! regulation of striated muscle tissue development GO:0016202 81 35 1,000 0,01152646 0,07800317 ! calcium-mediated signaling GO:0019722 67 35 1,000 0,01152646 0,07778769 ! placenta development GO:0001890 53 35 1,000 0,01152646 0,0775734 ! regulation of muscle development GO:0048634 82 36 1,000 0,01216762 0,08166348 ! mitotic sister chromatid segregation GO:0000070 63 36 1,000 0,01216762 0,08143975 ! regulation of proteolysis GO:0030162 77 36 1,000 0,01216762 0,08121723 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 1,000 0,01282408 0,08536575 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! regulation of smooth muscle cell proliferation GO:0048660 64 37 1,000 0,01282408 0,08513377 ! negative regulation of cell adhesion GO:0007162 94 37 1,000 0,01282408 0,08490306 ! sister chromatid segregation GO:0000819 65 37 1,000 0,01282408 0,08467359 ! tissue remodeling GO:0048771 78 37 1,000 0,01282408 0,08444536 ! maintenance of protein location in cell GO:0032507 89 37 1,000 0,01282408 0,08421836 ! regulation of microtubule-based process GO:0032886 86 37 1,000 0,01282408 0,08399257 ! positive regulation of DNA metabolic process GO:0051054 77 38 1,000 0,01349567 0,0881549 ! meiosis I GO:0007127 74 38 1,000 0,01349567 0,08791982 ! neural tube formation GO:0001841 79 38 1,000 0,01349567 0,08768599 ! regulation of metal ion transport GO:0010959 71 39 1,000 0,01418225 0,0919025 ! carbohydrate homeostasis GO:0033500 59 39 1,000 0,01418225 0,09165937 GO:0042593|glucose homeostasis, ! positive regulation of leukocyte proliferation GO:0070665 70 39 1,000 0,01418225 0,09141753 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! mammary gland development GO:0030879 93 40 1,000 0,01488366 0,09568629 ! regulation of action potential in neuron GO:0019228 80 40 1,000 0,01488366 0,09543515 ! maintenance of protein location GO:0045185 95 41 1,000 0,01559976 0,09976494 ! embryonic epithelial tube formation GO:0001838 85 41 1,000 0,01559976 0,09950445 ! cytokinesis GO:0000910 84 42 1,000 0,01633038 0,10389355 ! positive regulation of transcription factor activity GO:0051091 71 43 1,000 0,01707539 0,10835112 GO:0090047|positive regulation of transcription regulator activity, ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 1,000 0,01707539 0,10807042 ! glucose transport GO:0015758 66 43 1,000 0,01707539 0,10779117 ! striated muscle cell differentiation GO:0051146 91 43 1,000 0,01707539 0,10751336 ! segmentation GO:0035282 78 43 1,000 0,01707539 0,10723697 ! response to reactive oxygen species GO:0000302 75 44 1,000 0,01783464 0,111718 ! negative regulation of protein complex disassembly GO:0043242 113 44 1,000 0,01783464 0,11143228 ! hexose transport GO:0008645 68 44 1,000 0,01783464 0,11114801 GO:0015749|monosaccharide transport, ! biopolymer methylation GO:0043414 91 45 1,000 0,01860797 0,11567247 ! developmental growth GO:0048589 88 45 1,000 0,01860797 0,11537888 ! maintenance of location in cell GO:0051651 101 45 1,000 0,01860797 0,11508678 ! negative regulation of cell migration GO:0030336 122 46 1,000 0,01939525 0,11965304 ! polysaccharide biosynthetic process GO:0000271 79 46 1,000 0,01939525 0,11935164 ! neural tube development GO:0021915 91 47 1,000 0,02019633 0,12396894 ! cellular component disassembly GO:0022411 89 48 1,000 0,02101107 0,12864671 ! endosome transport GO:0016197 127 48 1,000 0,02101107 0,1283251 ! positive regulation of DNA binding GO:0043388 83 48 1,000 0,02101107 0,12800508 ! vascular process in circulatory system GO:0003018 85 48 1,000 0,02101107 0,12768666 ! methylation GO:0032259 97 48 1,000 0,02101107 0,12736982 ! regulation of action potential GO:0001508 102 50 1,000 0,02268094 0,13715232 ! regulation of ion transport GO:0043269 86 50 1,000 0,02268094 0,13681367 ! endocrine system development GO:0035270 109 50 1,000 0,02268094 0,13647669 ! activation of caspase activity GO:0006919 95 50 1,000 0,02268094 0,13614136 ! regulation of gene expression, epigenetic GO:0040029 116 50 1,000 0,02268094 0,13580768 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 0,02299745 0,13736621 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 0,02299745 0,13703117 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 0,02299745 0,13669776 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,02299745 0,13636597 ! positive regulation of helicase activity GO:0051096 12 5 0,000 0,02299745 0,13603579 ! neuron fate determination GO:0048664 7 5 0,000 0,02299745 0,1357072 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02299745 0,1353802 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 0,02299745 0,13505476 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 0,02299745 0,13473089 ! polyol transport GO:0015791 12 5 0,000 0,02299745 0,13440857 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,02299745 0,13408778 ! response to superoxide GO:0000303 10 5 0,000 0,02299745 0,13376853 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 0,02299745 0,13345079 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 0,02299745 0,13313455 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! female meiosis GO:0007143 10 5 0,000 0,02299745 0,13281981 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 0,02299745 0,13250656 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,02299745 0,13219478 ! hypothalamus development GO:0021854 9 5 0,000 0,02299745 0,13188446 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 0,02299745 0,1315756 ! cobalt ion transport GO:0006824 11 5 0,000 0,02299745 0,13126818 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 0,02299745 0,13096219 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 0,02299745 0,13065763 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,02299745 0,13035448 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,02299745 0,13005273 ! embryonic camera-type eye development GO:0031076 12 5 0,000 0,02299745 0,12975238 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,02299745 0,12945341 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02299745 0,12915582 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 0,02299745 0,12885959 ! transposition GO:0032196 9 5 0,000 0,02299745 0,12856472 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 0,02299745 0,12827119 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 0,000 0,02299745 0,127979 ! negative chemotaxis GO:0050919 16 5 0,000 0,02299745 0,12768814 ! positive regulation of histone modification GO:0031058 6 5 0,000 0,02299745 0,1273986 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,02299745 0,12711037 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 0,02299745 0,12682343 ! behavioral response to pain GO:0048266 10 5 0,000 0,02299745 0,1265378 ! clathrin coat assembly GO:0048268 15 5 0,000 0,02299745 0,12625344 ! Notch receptor processing GO:0007220 11 5 0,000 0,02299745 0,12597036 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02299745 0,12568855 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 0,02299745 0,12540799 ! micturition GO:0060073 9 5 0,000 0,02299745 0,12512869 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,02299745 0,12485063 ! copulation GO:0007620 9 5 0,000 0,02299745 0,12457379 ! glial cell fate commitment GO:0021781 14 5 0,000 0,02299745 0,12429819 ! protein maturation by protein folding GO:0022417 14 5 0,000 0,02299745 0,1240238 ! bioluminescence GO:0008218 9 5 0,000 0,02299745 0,12375062 ! spermidine metabolic process GO:0008216 7 5 0,000 0,02299745 0,12347864 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,02299745 0,12320785 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,02299745 0,12293825 ! apoptotic cell clearance GO:0043277 23 5 0,000 0,02299745 0,12266983 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,02299745 0,12240257 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 0,02299745 0,12213648 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,02299745 0,12187154 ! grooming behavior GO:0007625 6 5 0,000 0,02299745 0,12160775 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 0,02299745 0,1213451 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,02299745 0,12108358 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 0,02299745 0,12082319 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02299745 0,12056391 ! response to protozoan GO:0001562 13 5 0,000 0,02299745 0,12030574 ! lymph vessel development GO:0001945 10 5 0,000 0,02299745 0,12004868 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 0,02299745 0,11979271 ! endochondral ossification GO:0001958 17 5 0,000 0,02299745 0,11953783 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,02299745 0,11928404 ! single strand break repair GO:0000012 8 5 0,000 0,02299745 0,11903132 ! parathyroid gland development GO:0060017 14 5 0,000 0,02299745 0,11877966 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,02299745 0,11852907 ! cytokine secretion GO:0050663 15 5 0,000 0,02299745 0,11827954 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 0,02299745 0,11803105 ! ceramide catabolic process GO:0046514 7 5 0,000 0,02299745 0,11778361 ! skeletal myofibril assembly GO:0014866 12 5 0,000 0,02299745 0,1175372 ! smooth muscle tissue development GO:0048745 32 5 0,000 0,02299745 0,11729182 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,02299745 0,11704746 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,02299745 0,11680412 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,02299745 0,11656179 ! cardiac muscle fiber development GO:0048739 12 5 0,000 0,02299745 0,11632046 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,02299745 0,11608013 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 9 5 0,000 0,02299745 0,11584079 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,02299745 0,11560243 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 0,02299745 0,11536505 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,02299745 0,11512865 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 0,02299745 0,11489321 ! glycine biosynthetic process GO:0006545 7 5 0,000 0,02299745 0,11465874 ! microvillus organization GO:0032528 8 5 0,000 0,02299745 0,11442522 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 12 5 0,000 0,02299745 0,11419264 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 0,02299745 0,11396102 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 0,02299745 0,11373033 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 0,02299745 0,11350057 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 0,02299745 0,11327174 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 0,02299745 0,11304383 ! polyol catabolic process GO:0046174 9 5 0,000 0,02299745 0,11281683 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 0,02299745 0,11259074 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 0,02299745 0,11236556 ! muscle cell migration GO:0014812 8 5 0,000 0,02299745 0,11214128 ! mitochondrial fission GO:0000266 8 5 0,000 0,02299745 0,11191789 ! sister chromatid cohesion GO:0007062 15 5 0,000 0,02299745 0,11169539 ! response to tumor necrosis factor GO:0034612 10 5 0,000 0,02299745 0,11147377 ! mRNA transcription GO:0009299 10 5 0,000 0,02299745 0,11125303 ! nerve growth factor processing GO:0032455 9 5 0,000 0,02299745 0,11103316 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 0,02299745 0,11081416 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 0,02299745 0,11059603 ! anaerobic glycolysis GO:0019642 6 5 0,000 0,02299745 0,11037875 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,02299745 0,11016232 ! monocyte activation GO:0042117 10 5 0,000 0,02299745 0,10994673 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,02299745 0,10973199 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,02299745 0,10951809 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,02299745 0,10930502 ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 0,02299745 0,10909278 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02299745 0,10888136 ! forebrain neuron development GO:0021884 13 5 0,000 0,02299745 0,10867076 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,02299745 0,10846097 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 0,02299745 0,10825199 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,02299745 0,10804381 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02299745 0,10783643 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 0,02299745 0,10762985 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,02299745 0,10742406 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 0,02299745 0,10721905 ! lipid glycosylation GO:0030259 7 5 0,000 0,02299745 0,10701482 ! nucleobase transport GO:0015851 6 5 0,000 0,02299745 0,10681137 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02299745 0,10660869 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 0,02299745 0,10640678 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 0,02299745 0,10620564 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 0,02299745 0,10600525 ! basic amino acid transport GO:0015802 12 5 0,000 0,02299745 0,10580561 ! cellular glucose homeostasis GO:0001678 6 5 0,000 0,02299745 0,10560673 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 0,02299745 0,1054086 ! actin nucleation GO:0045010 11 5 0,000 0,02299745 0,1052112 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,02299745 0,10501454 ! depurination GO:0045007 5 5 0,000 0,02299745 0,10481862 ! depyrimidination GO:0045008 10 5 0,000 0,02299745 0,10462343 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,02299745 0,10442896 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02299745 0,10423522 ! G2/M transition checkpoint GO:0031576 8 5 0,000 0,02299745 0,10404219 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,02299745 0,10384987 ! zinc ion homeostasis GO:0055069 9 5 0,000 0,02299745 0,10365827 GO:0006882|cellular zinc ion homeostasis, ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 0,02299745 0,10346737 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02299745 0,10327717 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,02299745 0,10308767 ! activated T cell proliferation GO:0050798 16 5 0,000 0,02299745 0,10289887 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,02299745 0,10271075 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 0,02299745 0,10252332 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,02299745 0,10233658 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02299745 0,10215051 ! gamma-delta T cell activation GO:0046629 6 5 0,000 0,02299745 0,10196512 ! response to arsenic GO:0046685 11 5 0,000 0,02299745 0,1017804 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 0,02299745 0,10159635 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,02299745 0,10141296 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 0,02299745 0,10123024 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 0,02299745 0,10104817 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 0,02299745 0,10086675 ! response to cadmium ion GO:0046686 7 5 0,000 0,02299745 0,10068599 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 0,02299745 0,10050587 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 0,02299745 0,1003264 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 0,02299745 0,10014756 ! bile acid biosynthetic process GO:0006699 7 5 0,000 0,02299745 0,09996936 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 0,02299745 0,0997918 ! ganglioside catabolic process GO:0006689 12 5 0,000 0,02299745 0,09961486 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,02299745 0,09943855 ! decidualization GO:0046697 11 5 0,000 0,02299745 0,09926286 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 0,02299745 0,0990878 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 0,02299745 0,09891335 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 0,02299745 0,09873951 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 0,02299745 0,09856628 ! embryonic cleavage GO:0040016 6 5 0,000 0,02299745 0,09839366 ! peroxisome fission GO:0016559 5 5 0,000 0,02299745 0,09822165 ! histone demethylation GO:0016577 13 5 0,000 0,02299745 0,09805023 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 0,02299745 0,09787941 ! mitotic recombination GO:0006312 9 5 0,000 0,02299745 0,09770918 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 0,02299745 0,09753955 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,02299745 0,0973705 ! metaphase plate congression GO:0051310 7 5 0,000 0,02299745 0,09720204 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02299745 0,09703416 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,02299745 0,09686686 ! enteric nervous system development GO:0048484 8 5 0,000 0,02299745 0,09670014 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 0,02299745 0,09653399 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 0,02299745 0,09636841 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 0,02299745 0,09620339 ! muscle cell proliferation GO:0033002 12 5 0,000 0,02299745 0,09603894 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,02299745 0,09587505 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 0,02299745 0,09571172 ! B cell homeostasis GO:0001782 13 5 0,000 0,02299745 0,09554895 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 0,02299745 0,09538673 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,02299745 0,09522505 ! metaphase GO:0051323 11 5 0,000 0,02299745 0,09506393 ! melatonin biosynthetic process GO:0030187 7 5 0,000 0,02299745 0,09490335 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 0,02299745 0,09474331 ! cellular response to nutrient GO:0031670 8 5 0,000 0,02299745 0,09458381 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,02299745 0,09442484 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 0,02299745 0,09426641 ! regulation of hair follicle development GO:0051797 10 5 0,000 0,02299745 0,09410851 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 0,02299745 0,09395114 ! response to redox state GO:0051775 6 5 0,000 0,02299745 0,09379429 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 0,02299745 0,09363797 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 0,02299745 0,09348217 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,02299745 0,09332688 ! brown fat cell differentiation GO:0050873 7 5 0,000 0,02299745 0,09317211 ! regulation of telomerase activity GO:0051972 7 5 0,000 0,02299745 0,09301785 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02299745 0,0928641 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 0,02299745 0,09271086 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02299745 0,09255812 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 0,02299745 0,09240589 ! striatum development GO:0021756 14 5 0,000 0,02299745 0,09225416 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 0,02299745 0,09210292 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,02299745 0,09195218 ! glial cell migration GO:0008347 10 5 0,000 0,02299745 0,09180193 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,02299745 0,09165217 ! neural plate morphogenesis GO:0001839 7 5 0,000 0,02299745 0,0915029 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 0,02299745 0,09135412 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,02299745 0,09120581 ! T cell activation during immune response GO:0002286 9 5 0,000 0,02299745 0,09105799 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,02299745 0,09091065 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,02299745 0,09076378 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 0,02299745 0,09061739 ! neuroprotection GO:0043526 8 5 0,000 0,02299745 0,09047147 ! regulation of sensory perception GO:0051931 8 5 0,000 0,02299745 0,09032602 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,02299745 0,09018103 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,02299745 0,09003651 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 0,02299745 0,08989245 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 0,02299745 0,08974885 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,02299745 0,08960571 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 0,02299745 0,08946303 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,02299745 0,0893208 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 0,02299745 0,08917902 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 0,02299745 0,08903769 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,02299745 0,08889681 ! spindle assembly GO:0051225 6 5 0,000 0,02299745 0,08875637 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,02299745 0,08861637 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,02299745 0,08847682 ! protein palmitoylation GO:0018345 12 5 0,000 0,02299745 0,08833771 ! drug metabolic process GO:0017144 7 5 0,000 0,02299745 0,08819903 ! phospholipid scrambling GO:0017121 8 5 0,000 0,02299745 0,08806079 ! organ regeneration GO:0031100 7 5 0,000 0,02299745 0,08792298 ! carnitine metabolic process GO:0009437 8 5 0,000 0,02299745 0,0877856 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,02299745 0,08764864 ! response to temperature stimulus GO:0009266 84 51 1,000 0,02353579 0,08956066 ! positive regulation of binding GO:0051099 88 52 1,000 0,02440374 0,09271903 ! regulation of protein complex disassembly GO:0043244 127 52 1,000 0,02440374 0,09257506 ! morphogenesis of embryonic epithelium GO:0016331 106 52 1,000 0,02440374 0,09243153 ! histone modification GO:0016570 104 52 1,000 0,02440374 0,09228845 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 1,000 0,02440374 0,09214581 ! ribonucleoprotein complex assembly GO:0022618 104 52 1,000 0,02440374 0,09200361 ! vesicle organization GO:0016050 127 53 1,000 0,02528464 0,09517778 ! synapse organization GO:0050808 102 53 1,000 0,02528464 0,09503135 ! regulation of angiogenesis GO:0045765 125 54 1,000 0,02617836 0,09823922 ! activation of phospholipase C activity GO:0007202 110 54 1,000 0,02617836 0,09808855 GO:0010863|positive regulation of phospholipase C activity, ! covalent chromatin modification GO:0016569 115 54 1,000 0,02617836 0,09793833 ! regulation of cell shape GO:0008360 142 54 1,000 0,02617836 0,09778858 ! epithelial tube morphogenesis GO:0060562 114 54 1,000 0,02617836 0,09763929 ! positive regulation of phospholipase activity GO:0010518 111 55 1,000 0,02708476 0,10086595 ! regulation of multicellular organism growth GO:0040014 90 55 1,000 0,02708476 0,10071243 ! negative regulation of cell motion GO:0051271 142 55 1,000 0,02708476 0,10055937 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,02753347 0,1020702 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,02753347 0,10191555 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 0,02753347 0,10176137 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 0,02753347 0,10160765 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,02753347 0,1014544 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 0,02753347 0,1013016 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 0,02753347 0,10114927 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,02753347 0,10099739 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 0,02753347 0,10084597 ! response to oxygen radical GO:0000305 11 6 0,000 0,02753347 0,10069501 ! positive regulation of axon extension GO:0045773 13 6 0,000 0,02753347 0,10054449 ! myoblast cell fate commitment GO:0048625 18 6 0,000 0,02753347 0,10039443 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 0,02753347 0,10024481 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 0,02753347 0,10009563 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,02753347 0,0999469 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,02753347 0,09979861 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 0,02753347 0,09965076 ! forebrain regionalization GO:0021871 9 6 0,000 0,02753347 0,09950335 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,02753347 0,09935637 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,02753347 0,09920983 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 0,02753347 0,09906372 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,02753347 0,09891804 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 0,02753347 0,09877278 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,02753347 0,09862795 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 0,02753347 0,09848355 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 0,02753347 0,09833957 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,02753347 0,09819601 ! malate metabolic process GO:0006108 13 6 0,000 0,02753347 0,09805286 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 0,02753347 0,09791014 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 0,02753347 0,09776783 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 0,02753347 0,09762593 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 0,02753347 0,09748444 ! protein refolding GO:0042026 15 6 0,000 0,02753347 0,09734336 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,02753347 0,09720269 ! opsonization GO:0008228 8 6 0,000 0,02753347 0,09706243 ! mating behavior GO:0007617 7 6 0,000 0,02753347 0,09692257 ! erythrocyte maturation GO:0043249 8 6 0,000 0,02753347 0,09678311 ! embryonic hemopoiesis GO:0035162 16 6 0,000 0,02753347 0,09664406 ! protein amino acid dealkylation GO:0008214 15 6 0,000 0,02753347 0,0965054 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 0,02753347 0,09636714 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 0,02753347 0,09622928 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,02753347 0,09609181 ! response to interferon-gamma GO:0034341 16 6 0,000 0,02753347 0,09595473 ! toxin metabolic process GO:0009404 11 6 0,000 0,02753347 0,09581804 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,02753347 0,09568174 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 0,02753347 0,09554583 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 0,02753347 0,0954103 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 0,02753347 0,09527516 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 13 6 0,000 0,02753347 0,0951404 ! cGMP-mediated signaling GO:0019934 14 6 0,000 0,02753347 0,09500602 ! dorsal spinal cord development GO:0021516 10 6 0,000 0,02753347 0,09487202 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,02753347 0,0947384 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 0,02753347 0,09460515 ! thymic T cell selection GO:0045061 16 6 0,000 0,02753347 0,09447228 ! sphingoid catabolic process GO:0046521 8 6 0,000 0,02753347 0,09433978 ! protein lipoylation GO:0009249 10 6 0,000 0,02753347 0,09420765 ! transepithelial chloride transport GO:0030321 12 6 0,000 0,02753347 0,09407589 GO:0070633|transepithelial transport, ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,02753347 0,0939445 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 0,02753347 0,09381348 ! glutamate catabolic process GO:0006538 12 6 0,000 0,02753347 0,09368282 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 0,02753347 0,09355252 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,02753347 0,09342259 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 0,02753347 0,09329302 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,02753347 0,0931638 ! hyperosmotic response GO:0006972 10 6 0,000 0,02753347 0,09303494 ! L-serine biosynthetic process GO:0006564 7 6 0,000 0,02753347 0,09290644 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 0,02753347 0,0927783 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 0,02753347 0,0926505 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,02753347 0,09252306 ! urea metabolic process GO:0019627 7 6 0,000 0,02753347 0,09239597 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,02753347 0,09226922 ! neutrophil activation GO:0042119 7 6 0,000 0,02753347 0,09214283 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,02753347 0,09201678 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 0,02753347 0,09189107 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,02753347 0,09176571 ! paraxial mesoderm development GO:0048339 16 6 0,000 0,02753347 0,09164069 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 0,02753347 0,09151601 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,02753347 0,09139166 ! neuron apoptosis GO:0051402 15 6 0,000 0,02753347 0,09126766 ! T cell mediated immunity GO:0002456 17 6 0,000 0,02753347 0,09114399 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,02753347 0,09102066 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 0,02753347 0,09089766 ! carnitine transport GO:0015879 10 6 0,000 0,02753347 0,09077499 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,02753347 0,09065265 ! positive regulation of exocytosis GO:0045921 11 6 0,000 0,02753347 0,09053064 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 0,02753347 0,09040896 ! 5S class rRNA transcription GO:0042791 13 6 0,000 0,02753347 0,0902876 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,02753347 0,09016657 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 0,02753347 0,09004587 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 0,02753347 0,08992549 ! sodium ion homeostasis GO:0055078 12 6 0,000 0,02753347 0,08980543 ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 0,02753347 0,08968569 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,02753347 0,08956626 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 0,000 0,02753347 0,08944716 ! response to UV-C GO:0010225 14 6 0,000 0,02753347 0,08932837 ! astrocyte development GO:0014002 16 6 0,000 0,02753347 0,0892099 ! protein targeting to lysosome GO:0006622 12 6 0,000 0,02753347 0,08909174 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,02753347 0,0889739 ! interaction with symbiont GO:0051702 14 6 0,000 0,02753347 0,08885636 ! regulation of dendrite development GO:0050773 16 6 0,000 0,02753347 0,08873914 ! peptidyl-arginine modification GO:0018195 13 6 0,000 0,02753347 0,08862222 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 0,02753347 0,08850561 ! response to copper ion GO:0046688 10 6 0,000 0,02753347 0,08838931 ! response to exogenous dsRNA GO:0043330 13 6 0,000 0,02753347 0,08827331 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 0,02753347 0,08815762 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,02753347 0,08804223 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 0,02753347 0,08792714 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,02753347 0,08781236 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 0,02753347 0,08769787 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,02753347 0,08758368 ! nucleoside catabolic process GO:0009164 10 6 0,000 0,02753347 0,08746979 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,02753347 0,08735619 ! Schwann cell development GO:0014044 15 6 0,000 0,02753347 0,08724289 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 0,02753347 0,08712988 ! response to pheromone GO:0019236 6 6 0,000 0,02753347 0,08701716 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 0,02753347 0,08690473 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 0,02753347 0,0867926 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 0,02753347 0,08668075 ! base conversion or substitution editing GO:0016553 6 6 0,000 0,02753347 0,0865692 ! subpallium development GO:0021544 15 6 0,000 0,02753347 0,08645792 ! neural tube patterning GO:0021532 8 6 0,000 0,02753347 0,08634694 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 0,02753347 0,08623624 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 0,02753347 0,08612582 ! maintenance of organ identity GO:0048496 9 6 0,000 0,02753347 0,08601568 ! G2 phase GO:0051319 16 6 0,000 0,02753347 0,08590583 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 0,02753347 0,08579626 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 0,02753347 0,08568696 ! oxygen homeostasis GO:0032364 10 6 0,000 0,02753347 0,08557795 ! establishment of planar polarity GO:0001736 7 6 0,000 0,02753347 0,08546921 ! regulation of mast cell activation GO:0033003 13 6 0,000 0,02753347 0,08536074 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,02753347 0,08525255 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 0,02753347 0,08514464 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,02753347 0,085037 ! receptor internalization GO:0031623 11 6 0,000 0,02753347 0,08492963 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 0,02753347 0,08482253 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 0,02753347 0,0847157 ! neutrophil homeostasis GO:0001780 11 6 0,000 0,02753347 0,08460914 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,02753347 0,08450285 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 0,02753347 0,08439682 ! protein deubiquitination GO:0016579 16 6 0,000 0,02753347 0,08429106 ! negative regulation of neuroblast proliferation GO:0007406 25 6 0,000 0,02753347 0,08418556 ! protein destabilization GO:0031648 9 6 0,000 0,02753347 0,08408033 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 0,02753347 0,08397536 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,02753347 0,08387065 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 0,02753347 0,08376621 ! regulation of viral transcription GO:0046782 11 6 0,000 0,02753347 0,08366202 ! progesterone metabolic process GO:0042448 12 6 0,000 0,02753347 0,08355809 ! negative regulation of axon extension GO:0030517 24 6 0,000 0,02753347 0,08345442 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 0,02753347 0,08335101 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 0,02753347 0,08324785 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,02753347 0,08314495 ! determination of adult lifespan GO:0008340 17 6 0,000 0,02753347 0,0830423 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 0,02753347 0,08293991 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 0,02753347 0,08283776 ! neural plate development GO:0001840 9 6 0,000 0,02753347 0,08273587 ! catecholamine transport GO:0051937 9 6 0,000 0,02753347 0,08263423 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 0,02753347 0,08253284 ! sensory cilium assembly GO:0035058 10 6 0,000 0,02753347 0,0824317 ! organ or tissue specific immune response GO:0002251 8 6 0,000 0,02753347 0,0823308 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 0,02753347 0,08223015 ! maternal placenta development GO:0001893 12 6 0,000 0,02753347 0,08212975 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 0,02753347 0,08202959 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,02753347 0,08192968 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 0,02753347 0,08183001 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 0,02753347 0,08173058 ! positive regulation of coagulation GO:0050820 13 6 0,000 0,02753347 0,08163139 ! cellular anion homeostasis GO:0030002 11 6 0,000 0,02753347 0,08153244 GO:0055081|anion homeostasis, ! skeletal muscle fiber development GO:0048741 130 56 1,000 0,0280037 0,08282451 ! negative regulation of cytoskeleton organization GO:0051494 139 56 1,000 0,0280037 0,08272436 ! regulation of DNA replication GO:0006275 105 56 1,000 0,0280037 0,08262445 ! RNA elongation GO:0006354 90 56 1,000 0,0280037 0,08252478 ! regulation of bone remodeling GO:0046850 143 57 1,000 0,02893506 0,08516667 ! positive regulation of caspase activity GO:0043280 108 57 1,000 0,02893506 0,08506419 GO:0010952|positive regulation of peptidase activity, ! muscle fiber development GO:0048747 131 57 1,000 0,02893506 0,08496195 ! regulation of phospholipase activity GO:0010517 113 57 1,000 0,02893506 0,08485995 ! aging GO:0007568 112 58 1,000 0,02987869 0,08752234 ! regulation of tissue remodeling GO:0034103 146 58 1,000 0,02987869 0,08741752 ! positive regulation of organelle organization GO:0010638 108 58 1,000 0,02987869 0,08731295 ! positive regulation of lipase activity GO:0060193 115 58 1,000 0,02987869 0,08720864 ! maintenance of location GO:0051235 124 58 1,000 0,02987869 0,08710457 ! establishment of organelle localization GO:0051656 122 59 1,000 0,03083446 0,08978378 ! lipid modification GO:0030258 112 60 1,000 0,03180225 0,09249154 ! DNA catabolic process GO:0006308 94 60 1,000 0,03180225 0,09238156 ! tRNA transcription GO:0009304 17 7 0,000 0,03204855 0,09298647 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 0,03204855 0,09287617 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 0,03204855 0,09276613 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,03204855 0,09265634 ! regulation of helicase activity GO:0051095 16 7 0,000 0,03204855 0,09254682 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 0,03204855 0,09243756 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,03204855 0,09232855 ! sleep GO:0030431 16 7 0,000 0,03204855 0,0922198 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,03204855 0,09211131 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 0,03204855 0,09200307 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,03204855 0,09189508 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,03204855 0,09178735 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,03204855 0,09167987 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,03204855 0,09157264 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,03204855 0,09146567 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,03204855 0,09135894 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,03204855 0,09125246 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,03204855 0,09114623 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,03204855 0,09104024 ! SMAD protein complex assembly GO:0007183 13 7 0,000 0,03204855 0,09093451 ! glycolipid transport GO:0046836 11 7 0,000 0,03204855 0,09082901 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,03204855 0,09072377 GO:0051923|sulfation, ! neuron adhesion GO:0007158 14 7 0,000 0,03204855 0,09061876 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,03204855 0,090514 ! establishment of tissue polarity GO:0007164 8 7 0,000 0,03204855 0,09040948 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 0,03204855 0,0903052 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 0,03204855 0,09020116 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 0,03204855 0,09009736 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 0,03204855 0,0899938 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 0,03204855 0,08989048 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,03204855 0,0897874 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,03204855 0,08968455 ! lipoprotein transport GO:0042953 14 7 0,000 0,03204855 0,08958193 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,03204855 0,08947955 ! rhythmic behavior GO:0007622 17 7 0,000 0,03204855 0,08937741 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 0,03204855 0,0892755 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 0,03204855 0,08917382 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,03204855 0,08907237 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 0,03204855 0,08897115 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,03204855 0,08887016 ! regulation of odontogenesis GO:0042481 14 7 0,000 0,03204855 0,0887694 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,03204855 0,08866887 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 0,03204855 0,08856856 ! mechanosensory behavior GO:0007638 16 7 0,000 0,03204855 0,08846849 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 0,03204855 0,08836863 ! positive regulation of isotype switching GO:0045830 17 7 0,000 0,03204855 0,08826901 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 0,03204855 0,08816961 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,03204855 0,08807043 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,03204855 0,08797147 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,03204855 0,08787274 ! spinal cord patterning GO:0021511 14 7 0,000 0,03204855 0,08777423 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 0,03204855 0,08767593 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,03204855 0,08757786 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,03204855 0,08748001 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 0,03204855 0,08738238 ! adrenal gland development GO:0030325 17 7 0,000 0,03204855 0,08728496 ! cysteine metabolic process GO:0006534 13 7 0,000 0,03204855 0,08718776 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 0,03204855 0,08709078 ! ovulation GO:0030728 10 7 0,000 0,03204855 0,08699401 ! adenohypophysis development GO:0021984 11 7 0,000 0,03204855 0,08689746 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 0,03204855 0,08680112 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 0,03204855 0,08670499 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 0,03204855 0,08660908 ! microtubule nucleation GO:0007020 21 7 0,000 0,03204855 0,08651338 ! proline biosynthetic process GO:0006561 10 7 0,000 0,03204855 0,08641789 ! tryptophan metabolic process GO:0006568 11 7 0,000 0,03204855 0,08632261 ! thyroid hormone generation GO:0006590 13 7 0,000 0,03204855 0,08622754 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 0,03204855 0,08613268 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,03204855 0,08603803 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,03204855 0,08594359 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,03204855 0,08584935 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,03204855 0,08575532 ! galactose metabolic process GO:0006012 13 7 0,000 0,03204855 0,0856615 ! vesicle fusion GO:0006906 20 7 0,000 0,03204855 0,08556788 ! response to dietary excess GO:0002021 8 7 0,000 0,03204855 0,08547446 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,03204855 0,08538125 ! intracellular pH reduction GO:0051452 13 7 0,000 0,03204855 0,08528825 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,03204855 0,08519544 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 0,03204855 0,08510284 ! organ growth GO:0035265 15 7 0,000 0,03204855 0,08501043 ! nucleoside transport GO:0015858 11 7 0,000 0,03204855 0,08491823 ! nucleoside salvage GO:0043174 11 7 0,000 0,03204855 0,08482623 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 0,03204855 0,08473443 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,03204855 0,08464282 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 0,03204855 0,08455141 ! parturition GO:0007567 16 7 0,000 0,03204855 0,0844602 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 0,03204855 0,08436919 ! rRNA modification GO:0000154 14 7 0,000 0,03204855 0,08427837 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,03204855 0,08418775 ! spindle checkpoint GO:0031577 16 7 0,000 0,03204855 0,08409733 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 0,03204855 0,08400709 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,03204855 0,08391705 ! monocyte differentiation GO:0030224 16 7 0,000 0,03204855 0,08382721 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,03204855 0,08373755 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,03204855 0,08364809 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 0,03204855 0,08355882 ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,03204855 0,08346973 ! G1 DNA damage checkpoint GO:0031571 20 7 0,000 0,03204855 0,08338084 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,03204855 0,08329214 ! fibrinolysis GO:0042730 11 7 0,000 0,03204855 0,08320362 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,03204855 0,0831153 ! eating behavior GO:0042755 8 7 0,000 0,03204855 0,08302716 ! B cell lineage commitment GO:0002326 21 7 0,000 0,03204855 0,08293921 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,03204855 0,08285144 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 0,03204855 0,08276386 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 0,03204855 0,08267646 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,03204855 0,08258925 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 0,03204855 0,08250222 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,03204855 0,08241538 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 0,03204855 0,08232872 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 0,03204855 0,08224224 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 0,03204855 0,08215594 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 0,03204855 0,08206982 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,03204855 0,08198388 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 0,03204855 0,08189813 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,03204855 0,08181255 ! histone ubiquitination GO:0016574 9 7 0,000 0,03204855 0,08172715 ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 0,03204855 0,08164193 ! T cell lineage commitment GO:0002360 16 7 0,000 0,03204855 0,08155689 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 0,03204855 0,08147202 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,03204855 0,08138733 ! membrane to membrane docking GO:0022614 14 7 0,000 0,03204855 0,08130281 ! transcription termination GO:0006353 14 7 0,000 0,03204855 0,08121847 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,03204855 0,08113431 ! peptidyl-histidine modification GO:0018202 17 7 0,000 0,03204855 0,08105032 ! axonal fasciculation GO:0007413 19 7 0,000 0,03204855 0,0809665 ! negative regulation of nuclear division GO:0051784 15 7 0,000 0,03204855 0,08088286 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 0,03204855 0,08079939 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,03204855 0,08071609 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 0,03204855 0,08063297 ! diuresis GO:0030146 12 7 0,000 0,03204855 0,08055001 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,03204855 0,08046722 ! thiamin metabolic process GO:0006772 7 7 0,000 0,03204855 0,08038461 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,03204855 0,08030216 ! antibiotic transport GO:0042891 9 7 0,000 0,03204855 0,08021989 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,03204855 0,08013778 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 0,03204855 0,08005584 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 0,03204855 0,07997407 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 0,03204855 0,07989246 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,03204855 0,07981102 ! melanin biosynthetic process GO:0042438 10 7 0,000 0,03204855 0,07972975 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 0,03204855 0,07964864 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,03204855 0,07956769 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,03204855 0,07948691 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 0,03204855 0,0794063 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,03204855 0,07932585 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 0,03204855 0,07924556 ! endosome to lysosome transport GO:0008333 12 7 0,000 0,03204855 0,07916543 ! protein modification by small protein removal GO:0070646 19 7 0,000 0,03204855 0,07908546 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 0,03204855 0,07900566 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,03204855 0,07892602 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 0,03204855 0,07884654 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,03204855 0,07876721 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,03204855 0,07868805 ! muscle adaptation GO:0043500 13 7 0,000 0,03204855 0,07860905 ! retina homeostasis GO:0001895 12 7 0,000 0,03204855 0,0785302 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 0,03204855 0,07845151 ! protein amino acid prenylation GO:0018346 19 7 0,000 0,03204855 0,07837298 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 0,03204855 0,07829461 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 0,03204855 0,07821639 ! viral reproductive process GO:0022415 132 62 1,000 0,03377334 0,08234359 ! regulation of homeostatic process GO:0032844 148 62 1,000 0,03377334 0,08226149 ! mesoderm development GO:0007498 128 63 1,000 0,03477639 0,08462024 ! skeletal system morphogenesis GO:0048705 118 63 1,000 0,03477639 0,08453604 ! integrin-mediated signaling pathway GO:0007229 160 64 1,000 0,03579093 0,08691575 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,0365428 0,08865348 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,0365428 0,08856553 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 0,0365428 0,08847775 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 0,0365428 0,08839015 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,0365428 0,08830272 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,0365428 0,08821546 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,0365428 0,08812838 ! male meiosis GO:0007140 9 8 0,000 0,0365428 0,08804147 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,0365428 0,08795473 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,0365428 0,08786816 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,0365428 0,08778176 ! meiotic prophase I GO:0007128 14 8 0,000 0,0365428 0,08769553 ! response to zinc ion GO:0010043 12 8 0,000 0,0365428 0,08760947 ! regulation of lipid kinase activity GO:0043550 17 8 0,000 0,0365428 0,08752358 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,0365428 0,08743786 ! oligopeptide transport GO:0006857 16 8 0,000 0,0365428 0,0873523 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,0365428 0,08726691 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,0365428 0,08718169 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,0365428 0,08709663 ! signal peptide processing GO:0006465 12 8 0,000 0,0365428 0,08701175 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,0365428 0,08692702 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,0365428 0,08684246 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,0365428 0,08675807 ! succinate metabolic process GO:0006105 17 8 0,000 0,0365428 0,08667384 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,0365428 0,08658977 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,0365428 0,08650586 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,0365428 0,08642212 ! estrogen metabolic process GO:0008210 17 8 0,000 0,0365428 0,08633854 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,0365428 0,08625512 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,0365428 0,08617186 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,0365428 0,08608877 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,0365428 0,08600583 ! reflex GO:0060004 17 8 0,000 0,0365428 0,08592305 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,0365428 0,08584043 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,0365428 0,08575797 ! hemoglobin metabolic process GO:0020027 14 8 0,000 0,0365428 0,08567567 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,0365428 0,08559353 ! pigment granule organization GO:0048753 17 8 0,000 0,0365428 0,08551154 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,0365428 0,08542971 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,0365428 0,08534804 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,0365428 0,08526652 ! astrocyte differentiation GO:0048708 19 8 0,000 0,0365428 0,08518516 ! histidine catabolic process GO:0006548 10 8 0,000 0,0365428 0,08510396 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,0365428 0,08502291 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,0365428 0,08494201 ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,0365428 0,08486126 ! regulation of pigmentation during development GO:0048070 25 8 0,000 0,0365428 0,08478067 ! melanin metabolic process GO:0006582 17 8 0,000 0,0365428 0,08470024 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,0365428 0,08461995 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,0365428 0,08453982 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,0365428 0,08445984 ! macrophage activation GO:0042116 13 8 0,000 0,0365428 0,08438001 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,0365428 0,08430033 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! positive regulation of insulin secretion GO:0032024 17 8 0,000 0,0365428 0,0842208 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,0365428 0,08414142 ! purine salvage GO:0043101 12 8 0,000 0,0365428 0,08406219 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,0365428 0,08398311 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,0365428 0,08390418 ! osteoblast development GO:0002076 17 8 0,000 0,0365428 0,0838254 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,0365428 0,08374676 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,0365428 0,08366828 ! Schwann cell differentiation GO:0014037 21 8 0,000 0,0365428 0,08358993 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,0365428 0,08351174 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,0365428 0,08343369 ! response to UV-B GO:0010224 17 8 0,000 0,0365428 0,08335579 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,0365428 0,08327803 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,0365428 0,08320042 ! intermediate filament organization GO:0045109 12 8 0,000 0,0365428 0,08312295 ! cellular extravasation GO:0045123 13 8 0,000 0,0365428 0,08304563 ! response to antibiotic GO:0046677 11 8 0,000 0,0365428 0,08296845 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,0365428 0,08289141 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,0365428 0,08281452 ! response to tropane GO:0014073 15 8 0,000 0,0365428 0,08273777 GO:0042220|response to cocaine, ! melanosome transport GO:0032402 13 8 0,000 0,0365428 0,08266116 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,0365428 0,08258469 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,0365428 0,08250836 ! mast cell activation GO:0045576 14 8 0,000 0,0365428 0,08243218 ! multicellular organismal aging GO:0010259 20 8 0,000 0,0365428 0,08235614 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 0,0365428 0,08228023 ! gas homeostasis GO:0033483 14 8 0,000 0,0365428 0,08220447 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,0365428 0,08212884 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,0365428 0,08205336 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,0365428 0,08197801 ! nucleosome disassembly GO:0006337 14 8 0,000 0,0365428 0,0819028 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,0365428 0,08182773 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 0,0365428 0,08175279 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,0365428 0,081678 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,0365428 0,08160334 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,0365428 0,08152881 ! intracellular lipid transport GO:0032365 16 8 0,000 0,0365428 0,08145443 ! response to tumor cell GO:0002347 16 8 0,000 0,0365428 0,08138017 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,0365428 0,08130606 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,0365428 0,08123208 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 0,0365428 0,08115823 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,0365428 0,08108451 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 0,0365428 0,08101094 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,0365428 0,08093749 ! hormone catabolic process GO:0042447 17 8 0,000 0,0365428 0,08086418 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,0365428 0,080791 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,0365428 0,08071795 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,0365428 0,08064503 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,0365428 0,08057225 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,0365428 0,08049959 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,0365428 0,08042707 ! adult feeding behavior GO:0008343 10 8 0,000 0,0365428 0,08035468 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,0365428 0,08028242 ! ATP catabolic process GO:0006200 11 8 0,000 0,0365428 0,08021029 ! blastocyst growth GO:0001832 19 8 0,000 0,0365428 0,08013829 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,0365428 0,08006641 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,0365428 0,07999467 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,0365428 0,07992305 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,0365428 0,07985157 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,0365428 0,07978021 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,0365428 0,07970897 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,0365428 0,07963787 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,0365428 0,07956689 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,0365428 0,07949604 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 0,0365428 0,07942531 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,0365428 0,07935471 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 0,0365428 0,07928424 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,0365428 0,07921389 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,0365428 0,07914366 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 0,0365428 0,07907356 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 0,0365428 0,07900358 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,0365428 0,07893373 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 0,0365428 0,078864 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 0,0365428 0,0787944 ! activation of MAPK activity GO:0000187 124 67 1,000 0,03890227 0,08380798 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 1,000 0,03996154 0,08601412 ! viral reproduction GO:0016032 142 68 1,000 0,03996154 0,08593841 ! regulation of lipase activity GO:0060191 137 68 1,000 0,03996154 0,08586282 ! adaptive immune response GO:0002250 126 68 1,000 0,03996154 0,08578737 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! axon extension GO:0048675 16 9 0,000 0,0410163 0,08797438 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,0410163 0,08789721 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 0,0410163 0,08782018 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,0410163 0,08774328 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,0410163 0,08766651 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,0410163 0,08758988 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,0410163 0,08751338 ! reproductive behavior GO:0019098 22 9 0,000 0,0410163 0,08743702 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,0410163 0,08736079 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 0,0410163 0,08728469 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 0,0410163 0,08720872 ! UTP metabolic process GO:0046051 10 9 0,000 0,0410163 0,08713289 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,0410163 0,08705719 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,0410163 0,08698162 ! artery development GO:0060840 25 9 0,000 0,0410163 0,08690618 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,0410163 0,08683087 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,0410163 0,08675569 ! equilibrioception GO:0050957 20 9 0,000 0,0410163 0,08668064 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,0410163 0,08660572 ! chemosensory behavior GO:0007635 21 9 0,000 0,0410163 0,08653093 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,0410163 0,08645627 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,0410163 0,08638174 ! leukocyte degranulation GO:0043299 16 9 0,000 0,0410163 0,08630734 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,0410163 0,08623306 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,0410163 0,08615892 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,0410163 0,0860849 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,0410163 0,08601101 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,0410163 0,08593724 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,0410163 0,0858636 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,0410163 0,08579009 ! protein targeting to ER GO:0045047 25 9 0,000 0,0410163 0,0857167 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,0410163 0,08564344 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 0,0410163 0,0855703 ! T cell selection GO:0045058 27 9 0,000 0,0410163 0,08549729 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,0410163 0,0854244 ! glycine catabolic process GO:0006546 15 9 0,000 0,0410163 0,08535164 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,0410163 0,085279 ! endosome organization GO:0007032 20 9 0,000 0,0410163 0,08520648 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,0410163 0,08513409 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,0410163 0,08506182 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,0410163 0,08498967 ! mannose metabolic process GO:0006013 13 9 0,000 0,0410163 0,08491764 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,0410163 0,08484574 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,0410163 0,08477396 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 0,0410163 0,0847023 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,0410163 0,08463076 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,0410163 0,08455934 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,0410163 0,08448804 ! retinol metabolic process GO:0042572 20 9 0,000 0,0410163 0,08441687 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,0410163 0,08434581 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,0410163 0,08427487 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,0410163 0,08420405 ! macrophage differentiation GO:0030225 15 9 0,000 0,0410163 0,08413335 ! oligodendrocyte development GO:0014003 11 9 0,000 0,0410163 0,08406277 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 0,0410163 0,08399231 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,0410163 0,08392196 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,0410163 0,08385173 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,0410163 0,08378162 ! response to amine stimulus GO:0014075 13 9 0,000 0,0410163 0,08371163 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,0410163 0,08364175 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,0410163 0,08357199 ! erythrocyte development GO:0048821 17 9 0,000 0,0410163 0,08350235 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,0410163 0,08343282 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,0410163 0,08336341 ! renal water homeostasis GO:0003091 15 9 0,000 0,0410163 0,08329412 ! postreplication repair GO:0006301 25 9 0,000 0,0410163 0,08322493 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,0410163 0,08315587 ! icosanoid secretion GO:0032309 15 9 0,000 0,0410163 0,08308692 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,0410163 0,08301808 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,0410163 0,08294936 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,0410163 0,08288075 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,0410163 0,08281225 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,0410163 0,08274387 ! sterol catabolic process GO:0016127 14 9 0,000 0,0410163 0,08267559 GO:0006707|cholesterol catabolic process, ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,0410163 0,08260744 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,0410163 0,08253939 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,0410163 0,08247146 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 0,0410163 0,08240364 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,0410163 0,08233593 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 0,0410163 0,08226833 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,0410163 0,08220084 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,0410163 0,08213346 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,0410163 0,08206619 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,0410163 0,08199904 ! purine base metabolic process GO:0006144 25 9 0,000 0,0410163 0,08193199 ! pigment granule transport GO:0051904 17 9 0,000 0,0410163 0,08186505 ! regulation of telomere maintenance GO:0032204 17 9 0,000 0,0410163 0,08179822 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,0410163 0,0817315 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,0410163 0,08166489 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,0410163 0,08159839 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,0410163 0,08153199 ! mitochondrion localization GO:0051646 18 9 0,000 0,0410163 0,08146571 ! urogenital system development GO:0001655 149 69 1,000 0,04103167 0,08143003 ! homeostasis of number of cells GO:0048872 131 69 1,000 0,04103167 0,08136394 ! cellular amino acid catabolic process GO:0009063 120 69 1,000 0,04103167 0,08129795 ! developmental maturation GO:0021700 128 69 1,000 0,04103167 0,08123207 ! germ cell development GO:0007281 133 70 1,000 0,04211255 0,08330443 ! cell cycle checkpoint GO:0000075 145 71 1,000 0,04320407 0,08539444 ! cAMP-mediated signaling GO:0019933 124 71 1,000 0,04320407 0,08532541 ! carbohydrate transport GO:0008643 114 72 1,000 0,04430608 0,08743114 ! actin filament organization GO:0007015 167 72 1,000 0,04430608 0,08736058 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,04546916 0,08958158 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,04546916 0,08950939 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,04546916 0,08943732 ! associative learning GO:0008306 21 10 0,000 0,04546916 0,08936537 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,04546916 0,08929353 ! phosphate transport GO:0006817 24 10 0,000 0,04546916 0,08922181 ! cell volume homeostasis GO:0006884 17 10 0,000 0,04546916 0,0891502 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,04546916 0,08907871 ! CTP metabolic process GO:0046036 11 10 0,000 0,04546916 0,08900733 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 0,04546916 0,08893607 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,04546916 0,08886492 ! GTP metabolic process GO:0046039 11 10 0,000 0,04546916 0,08879389 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,04546916 0,08872297 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,04546916 0,08865216 ! social behavior GO:0035176 29 10 0,000 0,04546916 0,08858146 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,04546916 0,08851088 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,04546916 0,08844041 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,04546916 0,08837005 ! androgen metabolic process GO:0008209 17 10 0,000 0,04546916 0,0882998 ! phospholipid efflux GO:0033700 19 10 0,000 0,04546916 0,08822967 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,04546916 0,08815965 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,04546916 0,08808973 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,04546916 0,08801993 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,04546916 0,08795024 ! pathogenesis GO:0009405 17 10 0,000 0,04546916 0,08788066 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,04546916 0,08781119 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,04546916 0,08774183 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,04546916 0,08767258 ! endoderm development GO:0007492 18 10 0,000 0,04546916 0,08760343 ! arginine catabolic process GO:0006527 17 10 0,000 0,04546916 0,0875344 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,04546916 0,08746547 ! proline metabolic process GO:0006560 13 10 0,000 0,04546916 0,08739666 ! phosphagen metabolic process GO:0006599 17 10 0,000 0,04546916 0,08732795 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,04546916 0,08725935 ! V(D)J recombination GO:0033151 34 10 0,000 0,04546916 0,08719086 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,04546916 0,08712247 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,04546916 0,0870542 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,04546916 0,08698602 ! B cell proliferation GO:0042100 19 10 0,000 0,04546916 0,08691796 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,04546916 0,08685 ! multicellular organism growth GO:0035264 19 10 0,000 0,04546916 0,08678215 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,04546916 0,08671441 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,04546916 0,08664677 ! ruffle organization GO:0031529 17 10 0,000 0,04546916 0,08657923 ! epithelial cell development GO:0002064 21 10 0,000 0,04546916 0,0865118 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,04546916 0,08644448 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,04546916 0,08637726 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,04546916 0,08631014 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,04546916 0,08624313 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,04546916 0,08617622 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,04546916 0,08610942 GO:0030204|chondroitin sulfate metabolic process, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 0,000 0,04546916 0,08604272 ! copper ion homeostasis GO:0055070 13 10 0,000 0,04546916 0,08597612 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,04546916 0,08590963 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,04546916 0,08584324 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,04546916 0,08577695 ! segment specification GO:0007379 15 10 0,000 0,04546916 0,08571077 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,04546916 0,08564468 ! blastoderm segmentation GO:0007350 19 10 0,000 0,04546916 0,0855787 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,04546916 0,08551282 ! response to dsRNA GO:0043331 23 10 0,000 0,04546916 0,08544704 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,04546916 0,08538136 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,04546916 0,08531579 ! melanosome localization GO:0032400 16 10 0,000 0,04546916 0,08525031 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,04546916 0,08518493 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,04546916 0,08511966 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,04546916 0,08505448 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,04546916 0,08498941 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,04546916 0,08492443 ! induction of an organ GO:0001759 17 10 0,000 0,04546916 0,08485955 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,04546916 0,08479477 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,04546916 0,08473009 ! protein sumoylation GO:0016925 17 10 0,000 0,04546916 0,08466551 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,04546916 0,08460103 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,04546916 0,08453665 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,04546916 0,08447236 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,04546916 0,08440817 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,04546916 0,08434408 ! salivary gland development GO:0007431 28 10 0,000 0,04546916 0,08428009 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,04546916 0,08421619 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,04546916 0,08415239 ! midbrain development GO:0030901 14 10 0,000 0,04546916 0,08408869 ! musculoskeletal movement GO:0050881 16 10 0,000 0,04546916 0,08402508 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,04546916 0,08396157 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,04546916 0,08389815 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,04546916 0,08383483 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,04546916 0,08377161 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,04546916 0,08370848 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,04546916 0,08364545 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,04546916 0,08358251 ! detection of calcium ion GO:0005513 24 10 0,000 0,04546916 0,08351966 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,04546916 0,08345691 ! blastocyst formation GO:0001825 18 10 0,000 0,04546916 0,08339426 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,04546916 0,0833317 ! cerebellar cortex development GO:0021695 16 10 0,000 0,04546916 0,08326923 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,04546916 0,08320686 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,04546916 0,08314458 ! response to nicotine GO:0035094 20 10 0,000 0,04546916 0,08308239 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,04546916 0,08302029 ! regulation of caspase activity GO:0043281 136 74 1,000 0,04654115 0,08491414 ! organelle localization GO:0051640 155 74 1,000 0,04654115 0,08485077 ! reproductive structure development GO:0048608 131 75 1,000 0,04767397 0,08685124 ! axon guidance GO:0007411 162 75 1,000 0,04767397 0,08678652 ! cell-matrix adhesion GO:0007160 181 76 1,000 0,04881682 0,08880082 ! respiratory burst GO:0045730 17 11 0,000 0,04990146 0,09070631 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,04990146 0,09063887 ! neuron fate specification GO:0048665 18 11 0,000 0,04990146 0,09057153 ! telencephalon cell migration GO:0022029 23 11 0,000 0,04990146 0,09050429 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,04990146 0,09043715 ! synapsis GO:0007129 14 11 0,000 0,04990146 0,09037011 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,04990146 0,09030317 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,04990146 0,09023633 ! response to pain GO:0048265 27 11 0,000 0,04990146 0,09016958 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,04990146 0,09010294 ! keratinocyte proliferation GO:0043616 19 11 0,000 0,04990146 0,09003639 ! bone resorption GO:0045453 16 11 0,000 0,04990146 0,08996995 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,04990146 0,0899036 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,04990146 0,08983735 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,04990146 0,08977119 ! melanocyte differentiation GO:0030318 20 11 0,000 0,04990146 0,08970514 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,04990146 0,08963918 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,04990146 0,08957331 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,04990146 0,08950755 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,04990146 0,08944188 ! regulation of intracellular pH GO:0051453 21 11 0,000 0,04990146 0,0893763 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,04990146 0,08931083 ! UV protection GO:0009650 20 11 0,000 0,04990146 0,08924545 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,04990146 0,08918016 ! temperature homeostasis GO:0001659 18 11 0,000 0,04990146 0,08911497 ! behavioral fear response GO:0001662 27 11 0,000 0,04990146 0,08904987 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,04990146 0,08898487 ! negative regulation of ossification GO:0030279 27 11 0,000 0,04990146 0,08891997 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,04990146 0,08885516 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,04990146 0,08879044 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 0,04990146 0,08872582 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,04990146 0,08866129 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,04990146 0,08859686 ! regulation of organ growth GO:0046620 14 11 0,000 0,04990146 0,08853252 ! pigment granule localization GO:0051875 20 11 0,000 0,04990146 0,08846827 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,04990146 0,08840412 ! vasoconstriction GO:0042310 20 11 0,000 0,04990146 0,08834006 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,04990146 0,08827609 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,04990146 0,08821221 ! embryonic axis specification GO:0000578 19 11 0,000 0,04990146 0,08814843 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,04990146 0,08808474 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,04990146 0,08802114 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,04990146 0,08795763 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,04990146 0,08789422 GO:0006809|nitric oxide biosynthetic process, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,04990146 0,08783089 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,04990146 0,08776766 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,04990146 0,08770452 ! prophase GO:0051324 17 11 0,000 0,04990146 0,08764147 ! neuroblast proliferation GO:0007405 25 11 0,000 0,04990146 0,0875785 ! nucleosome positioning GO:0016584 15 11 0,000 0,04990146 0,08751563 ! regulation of isotype switching GO:0045191 24 11 0,000 0,04990146 0,08745285 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,04990146 0,08739016 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,04990146 0,08732756 ! apical protein localization GO:0045176 18 11 0,000 0,04990146 0,08726505 ! acid secretion GO:0046717 20 11 0,000 0,04990146 0,08720263 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,04990146 0,0871403 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,04990146 0,08707806 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,04990146 0,0870159 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,04990146 0,08695384 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 0,04990146 0,08689186 ! cholesterol efflux GO:0033344 21 11 0,000 0,04990146 0,08682997 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,04990146 0,08676817 ! oocyte development GO:0048599 20 11 0,000 0,04990146 0,08670646 ! germ cell migration GO:0008354 26 11 0,000 0,04990146 0,08664483 ! embryonic gut development GO:0048566 19 11 0,000 0,04990146 0,08658329 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,04990146 0,08652184 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,04990146 0,08646048 ! activation of innate immune response GO:0002218 16 11 0,000 0,04990146 0,08639921 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,04990146 0,08633802 ! lysogeny GO:0030069 22 11 0,000 0,04990146 0,08627691 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,04990146 0,0862159 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,04990146 0,08615497 ! sequestering of metal ion GO:0051238 15 11 0,000 0,04990146 0,08609412 ! nucleus localization GO:0051647 22 11 0,000 0,04990146 0,08603337 ! amine catabolic process GO:0009310 136 77 1,000 0,04996959 0,08609006 ! phosphoinositide metabolic process GO:0030384 146 77 1,000 0,04996959 0,08602939 ! regulation of endopeptidase activity GO:0052548 141 77 1,000 0,04996959 0,08596881 ! positive regulation of lymphocyte activation GO:0051251 142 78 1,000 0,05113216 0,08790701 ! response to steroid hormone stimulus GO:0048545 147 79 1,000 0,05230441 0,08985912 ! protein oligomerization GO:0051259 149 79 1,000 0,05230441 0,08979597 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 1,000 0,05348623 0,09176044 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,05431331 0,09311398 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,05431331 0,09304869 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,05431331 0,09298348 ! mating GO:0007618 17 12 0,000 0,05431331 0,09291837 ! protein complex disassembly GO:0043241 28 12 0,000 0,05431331 0,09285334 GO:0043624|cellular protein complex disassembly, ! regulation of cell projection assembly GO:0060491 33 12 0,000 0,05431331 0,09278841 ! hippocampus development GO:0021766 29 12 0,000 0,05431331 0,09272357 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,05431331 0,09265882 ! T cell proliferation GO:0042098 32 12 0,000 0,05431331 0,09259416 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,05431331 0,09252959 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,05431331 0,09246511 ! ventral spinal cord development GO:0021517 25 12 0,000 0,05431331 0,09240072 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,05431331 0,09233641 ! drug transport GO:0015893 16 12 0,000 0,05431331 0,0922722 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,05431331 0,09220808 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,05431331 0,09214405 ! polyamine metabolic process GO:0006595 18 12 0,000 0,05431331 0,0920801 ! focal adhesion formation GO:0048041 37 12 0,000 0,05431331 0,09201625 ! mitotic spindle organization GO:0007052 23 12 0,000 0,05431331 0,09195248 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,05431331 0,0918888 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,05431331 0,09182521 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,05431331 0,09176171 ! lipid digestion GO:0044241 21 12 0,000 0,05431331 0,09169829 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,05431331 0,09163496 ! entry into host cell GO:0030260 34 12 0,000 0,05431331 0,09157172 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,05431331 0,09150857 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,05431331 0,0914455 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,05431331 0,09138253 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,05431331 0,09131963 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,05431331 0,09125683 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,05431331 0,09119411 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,05431331 0,09113147 ! snRNA metabolic process GO:0016073 30 12 0,000 0,05431331 0,09106893 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,05431331 0,09100647 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,05431331 0,09094409 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,05431331 0,0908818 ! cranial nerve development GO:0021545 23 12 0,000 0,05431331 0,09081959 ! fucose catabolic process GO:0019317 25 12 0,000 0,05431331 0,09075747 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,05431331 0,09069544 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,05431331 0,09063349 ! autonomic nervous system development GO:0048483 24 12 0,000 0,05431331 0,09057162 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 0,05431331 0,09050984 ! zymogen activation GO:0031638 18 12 0,000 0,05431331 0,09044814 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,05431331 0,09038653 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,05431331 0,090325 ! oocyte differentiation GO:0009994 21 12 0,000 0,05431331 0,09026356 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,05431331 0,09020219 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,05431331 0,09014092 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,05431331 0,09007972 ! defense response to fungus GO:0050832 15 12 0,000 0,05431331 0,09001861 ! developmental induction GO:0031128 22 12 0,000 0,05431331 0,08995758 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 21 12 0,000 0,05431331 0,08989663 ! lamellipodium assembly GO:0030032 24 12 0,000 0,05431331 0,08983577 ! response to cold GO:0009409 17 12 0,000 0,05431331 0,08977498 ! establishment of cell polarity GO:0030010 21 12 0,000 0,05431331 0,08971428 ! regulation of synapse organization GO:0050807 18 12 0,000 0,05431331 0,08965367 ! meiosis GO:0007126 143 81 1,000 0,05467752 0,09019391 GO:0051327|M phase of meiotic cell cycle, ! muscle cell differentiation GO:0042692 178 81 1,000 0,05467752 0,09013305 ! regulation of peptidase activity GO:0052547 150 82 1,000 0,05587815 0,09205011 ! cell-substrate adhesion GO:0031589 189 82 1,000 0,05587815 0,09198808 ! protein import into nucleus GO:0006606 174 82 1,000 0,05587815 0,09192614 ! meiotic cell cycle GO:0051321 144 82 1,000 0,05587815 0,09186428 ! regulation of adenylate cyclase activity GO:0045761 165 83 1,000 0,05708802 0,0937902 ! response to drug GO:0042493 149 83 1,000 0,05708802 0,09372716 ! nuclear import GO:0051170 177 83 1,000 0,05708802 0,09366422 ! response to metal ion GO:0010038 158 84 1,000 0,05830701 0,09560001 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,0587048 0,09618768 ! cGMP metabolic process GO:0046068 18 13 0,000 0,0587048 0,09612321 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,0587048 0,09605883 ! regulation of chemokine production GO:0032642 18 13 0,000 0,0587048 0,09599453 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,0587048 0,09593032 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,0587048 0,0958662 ! peroxisomal transport GO:0043574 28 13 0,000 0,0587048 0,09580216 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,0587048 0,0957382 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,0587048 0,09567434 ! organelle fusion GO:0048284 36 13 0,000 0,0587048 0,09561055 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,0587048 0,09554685 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,0587048 0,09548324 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,0587048 0,09541971 ! endocrine pancreas development GO:0031018 25 13 0,000 0,0587048 0,09535627 ! positive regulation of cell growth GO:0030307 24 13 0,000 0,0587048 0,09529291 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,0587048 0,09522963 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,0587048 0,09516644 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,0587048 0,09510334 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,0587048 0,09504031 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,0587048 0,09497737 ! methionine metabolic process GO:0006555 31 13 0,000 0,0587048 0,09491451 ! plasma membrane organization GO:0007009 27 13 0,000 0,0587048 0,09485174 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,0587048 0,09478905 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,0587048 0,09472644 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,0587048 0,09466391 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,0587048 0,09460147 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! response to X-ray GO:0010165 28 13 0,000 0,0587048 0,09453911 ! cytokine metabolic process GO:0042107 24 13 0,000 0,0587048 0,09447683 ! cellular carbohydrate catabolic process GO:0044275 17 13 0,000 0,0587048 0,09441463 ! exocrine system development GO:0035272 34 13 0,000 0,0587048 0,09435252 ! asymmetric protein localization GO:0008105 24 13 0,000 0,0587048 0,09429049 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,0587048 0,09422853 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 0,0587048 0,09416666 ! L-glutamate transport GO:0015813 30 13 0,000 0,0587048 0,09410487 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,0587048 0,09404317 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,0587048 0,09398154 ! protein homotetramerization GO:0051289 24 13 0,000 0,0587048 0,09391999 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,0587048 0,09385853 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,0587048 0,09379714 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,0587048 0,09373584 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,0587048 0,09367461 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,0587048 0,09361347 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,0587048 0,0935524 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,0587048 0,09349141 ! histone methylation GO:0016571 29 13 0,000 0,0587048 0,09343051 ! chromatin silencing GO:0006342 29 13 0,000 0,0587048 0,09336968 ! gland morphogenesis GO:0022612 31 13 0,000 0,0587048 0,09330893 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,0587048 0,09324826 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 0,0587048 0,09318767 ! regulation of epidermis development GO:0045682 19 13 0,000 0,0587048 0,09312716 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,0587048 0,09306673 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,0587048 0,09300637 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,0587048 0,0929461 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,0587048 0,0928859 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,0587048 0,09282578 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,0587048 0,09276574 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,0587048 0,09270577 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,0587048 0,09264588 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,0587048 0,09258607 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,0587048 0,09252634 ! insulin secretion GO:0030073 24 13 0,000 0,0587048 0,09246669 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,0587048 0,09240711 ! acrosome reaction GO:0007340 19 13 0,000 0,0587048 0,0923476 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,0587048 0,09228818 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,0587048 0,09222883 ! regulation of cyclase activity GO:0031279 168 85 1,000 0,05953502 0,09347303 ! regulation of neuron differentiation GO:0045664 187 85 1,000 0,05953502 0,093413 ! regulation of cAMP biosynthetic process GO:0030817 173 86 1,000 0,06077193 0,09529257 ! regulation of lyase activity GO:0051339 169 86 1,000 0,06077193 0,09523145 ! positive regulation of cell activation GO:0050867 161 86 1,000 0,06077193 0,0951704 GO:0002696|positive regulation of leukocyte activation, ! rRNA transcription GO:0009303 28 14 0,000 0,06307602 0,09871538 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,06307602 0,09865218 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 0,06307602 0,09858907 ! water transport GO:0006833 21 14 0,000 0,06307602 0,09852603 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,06307602 0,09846307 ! non-recombinational repair GO:0000726 29 14 0,000 0,06307602 0,0984002 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,06307602 0,0983374 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,06307602 0,09827469 ! hair follicle morphogenesis GO:0031069 27 14 0,000 0,06307602 0,09821205 ! RNA polyadenylation GO:0043631 32 14 0,000 0,06307602 0,0981495 ! lipid localization GO:0010876 32 14 0,000 0,06307602 0,09808702 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 0,06307602 0,09802463 ! regulated secretory pathway GO:0045055 24 14 0,000 0,06307602 0,09796231 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,06307602 0,09790007 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,06307602 0,09783791 ! arginine metabolic process GO:0006525 21 14 0,000 0,06307602 0,09777583 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,06307602 0,09771383 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,06307602 0,09765191 ! regulation of heart rate GO:0002027 25 14 0,000 0,06307602 0,09759006 ! fear response GO:0042596 34 14 0,000 0,06307602 0,0975283 ! organic alcohol transport GO:0015850 29 14 0,000 0,06307602 0,09746661 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,06307602 0,097405 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 0,000 0,06307602 0,09734347 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,06307602 0,09728202 ! neutral amino acid transport GO:0015804 28 14 0,000 0,06307602 0,09722064 ! bone mineralization GO:0030282 18 14 0,000 0,06307602 0,09715934 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,06307602 0,09709812 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,06307602 0,09703697 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,06307602 0,0969759 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,06307602 0,09691491 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,06307602 0,096854 ! regulation of cellular pH GO:0030641 27 14 0,000 0,06307602 0,09679316 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,06307602 0,0967324 ! ribosome assembly GO:0042255 18 14 0,000 0,06307602 0,09667171 ! cerebellum development GO:0021549 23 14 0,000 0,06307602 0,0966111 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,06307602 0,09655057 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,06307602 0,09649011 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,06307602 0,09642973 ! response to gamma radiation GO:0010332 30 14 0,000 0,06307602 0,09636943 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,06307602 0,0963092 ! NADP metabolic process GO:0006739 24 14 0,000 0,06307602 0,09624904 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,06307602 0,09618896 ! oxygen transport GO:0015671 22 14 0,000 0,06307602 0,09612895 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,06307602 0,09606902 ! male genitalia development GO:0030539 26 14 0,000 0,06307602 0,09600917 ! regulation of axon extension GO:0030516 43 14 0,000 0,06307602 0,09594938 ! release of cytochrome c from mitochondria GO:0001836 31 14 0,000 0,06307602 0,09588968 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,06307602 0,09583004 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 0,06307602 0,09577049 ! one-carbon metabolic process GO:0006730 167 88 1,000 0,06327205 0,09600846 ! regulation of cAMP metabolic process GO:0030814 182 89 1,000 0,06453504 0,09786412 ! tube morphogenesis GO:0035239 194 89 1,000 0,06453504 0,09780341 ! protein localization in nucleus GO:0034504 192 89 1,000 0,06453504 0,09774278 ! response to inorganic substance GO:0010035 173 90 1,000 0,06580651 0,09960676 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 1,000 0,06708636 0,1014811 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,06742706 0,10193336 ! lactation GO:0007595 30 15 0,000 0,06742706 0,10187032 ! reproductive cellular process GO:0048610 22 15 0,000 0,06742706 0,10180736 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,06742706 0,10174447 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,06742706 0,10168167 ! superoxide anion generation GO:0042554 22 15 0,000 0,06742706 0,10161894 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,06742706 0,10155629 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,06742706 0,10149372 ! copper ion transport GO:0006825 22 15 0,000 0,06742706 0,10143122 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,06742706 0,1013688 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,06742706 0,10130646 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,06742706 0,10124419 ! sulfate transport GO:0008272 27 15 0,000 0,06742706 0,101182 ! response to cAMP GO:0051591 25 15 0,000 0,06742706 0,10111989 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,06742706 0,10105785 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,06742706 0,10099589 ! regulation of mRNA processing GO:0050684 26 15 0,000 0,06742706 0,10093401 ! response to hexose stimulus GO:0009746 25 15 0,000 0,06742706 0,1008722 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,06742706 0,10081047 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,06742706 0,10074881 ! vesicle coating GO:0006901 38 15 0,000 0,06742706 0,10068723 ! regulation of exocytosis GO:0017157 26 15 0,000 0,06742706 0,10062572 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,06742706 0,10056429 ! G1/S transition checkpoint GO:0031575 37 15 0,000 0,06742706 0,10050293 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,06742706 0,10044165 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,06742706 0,10038044 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,06742706 0,10031931 ! regulation of vasodilation GO:0042312 27 15 0,000 0,06742706 0,10025825 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,06742706 0,10019726 ! histone deacetylation GO:0016575 24 15 0,000 0,06742706 0,10013635 ! water homeostasis GO:0030104 28 15 0,000 0,06742706 0,10007552 ! cofactor transport GO:0051181 30 15 0,000 0,06742706 0,10001476 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,06742706 0,09995407 ! muscle maintenance GO:0046716 26 15 0,000 0,06742706 0,09989345 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,06742706 0,09983291 ! intestinal absorption GO:0050892 31 15 0,000 0,06742706 0,09977244 ! dopamine metabolic process GO:0042417 35 15 0,000 0,06742706 0,09971205 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,06742706 0,09965173 ! heme biosynthetic process GO:0006783 33 15 0,000 0,06742706 0,09959148 ! cell killing GO:0001906 32 15 0,000 0,06742706 0,0995313 ! epithelial to mesenchymal transition GO:0001837 30 15 0,000 0,06742706 0,0994712 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,06742706 0,09941117 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,06742706 0,09935121 ! actin filament polymerization GO:0030041 27 15 0,000 0,06742706 0,09929132 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,06742706 0,09923151 ! regulation of cell morphogenesis GO:0022604 243 93 1,000 0,06967076 0,1024718 ! nitrogen compound catabolic process GO:0044270 167 94 1,000 0,07097511 0,10432743 ! carbohydrate biosynthetic process GO:0016051 158 94 1,000 0,07097511 0,10426469 ! regulation of membrane potential GO:0042391 179 94 1,000 0,07097511 0,10420203 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,07175801 0,10528819 ! positive regulation of cell size GO:0045793 29 16 0,000 0,07175801 0,10522499 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,07175801 0,10516186 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,07175801 0,10509882 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,07175801 0,10503585 ! bone remodeling GO:0046849 28 16 0,000 0,07175801 0,10497295 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 0,000 0,07175801 0,10491013 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,07175801 0,10484739 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,07175801 0,10478472 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,07175801 0,10472212 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,07175801 0,1046596 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,07175801 0,10459715 ! startle response GO:0001964 28 16 0,000 0,07175801 0,10453478 ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,07175801 0,10447248 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,07175801 0,10441026 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,07175801 0,10434811 ! protein polyubiquitination GO:0000209 41 16 0,000 0,07175801 0,10428604 ! glutamate metabolic process GO:0006536 25 16 0,000 0,07175801 0,10422404 ! pituitary gland development GO:0021983 30 16 0,000 0,07175801 0,10416211 ! response to osmotic stress GO:0006970 27 16 0,000 0,07175801 0,10410025 ! lysosomal transport GO:0007041 31 16 0,000 0,07175801 0,10403847 ! fructose metabolic process GO:0006000 25 16 0,000 0,07175801 0,10397677 ! L-amino acid transport GO:0015807 33 16 0,000 0,07175801 0,10391513 ! stem cell development GO:0048864 46 16 0,000 0,07175801 0,10385357 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,07175801 0,10379208 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,07175801 0,10373067 ! intermediate filament-based process GO:0045103 36 16 0,000 0,07175801 0,10366933 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,07175801 0,10360805 ! negative regulation of immune response GO:0050777 38 16 0,000 0,07175801 0,10354686 ! axon cargo transport GO:0008088 46 16 0,000 0,07175801 0,10348573 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,07175801 0,10342468 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,07175801 0,1033637 ! DNA replication initiation GO:0006270 28 16 0,000 0,07175801 0,10330279 ! neuron recognition GO:0008038 40 16 0,000 0,07175801 0,10324195 ! mRNA splice site selection GO:0006376 44 16 0,000 0,07175801 0,10318118 ! tissue regeneration GO:0042246 27 16 0,000 0,07175801 0,10312049 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,07175801 0,10305986 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,07175801 0,10299931 ! biomineral formation GO:0031214 22 16 0,000 0,07175801 0,10293883 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,07175801 0,10287842 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,07175801 0,10281808 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,07175801 0,10275781 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,07175801 0,10269762 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,07175801 0,10263749 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,07175801 0,10257743 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,07175801 0,10251744 ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,07175801 0,10245753 ! peptide hormone processing GO:0016486 27 16 0,000 0,07175801 0,10239768 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 1,000 0,07228742 0,10309291 ! sex differentiation GO:0007548 171 96 1,000 0,07360759 0,10491444 ! regulation of DNA metabolic process GO:0051052 188 97 1,000 0,07493553 0,1067449 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,07606898 0,10829634 ! metencephalon development GO:0022037 32 17 0,000 0,07606898 0,10823326 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,07606898 0,10817026 ! filopodium assembly GO:0046847 42 17 0,000 0,07606898 0,10810734 ! endothelial cell migration GO:0043542 31 17 0,000 0,07606898 0,10804448 ! gene silencing by RNA GO:0031047 38 17 0,000 0,07606898 0,1079817 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,07606898 0,107919 ! glial cell development GO:0021782 28 17 0,000 0,07606898 0,10785636 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,07606898 0,1077938 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,07606898 0,10773131 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,07606898 0,1076689 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 0,000 0,07606898 0,10760655 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,07606898 0,10754428 ! myoblast differentiation GO:0045445 50 17 0,000 0,07606898 0,10748208 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,07606898 0,10741995 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,07606898 0,10735789 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,07606898 0,10729591 ! NAD metabolic process GO:0019674 33 17 0,000 0,07606898 0,107234 ! membrane budding GO:0006900 42 17 0,000 0,07606898 0,10717215 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,07606898 0,10711038 ! regulation of protein binding GO:0043393 33 17 0,000 0,07606898 0,10704868 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,07606898 0,10698705 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,07606898 0,1069255 ! genitalia development GO:0048806 32 17 0,000 0,07606898 0,10686401 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,07606898 0,10680259 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,07606898 0,10674125 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,07606898 0,10667997 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,07606898 0,10661877 ! steroid catabolic process GO:0006706 34 17 0,000 0,07606898 0,10655763 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,07606898 0,10649657 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,07606898 0,10643557 ! gas transport GO:0015669 26 17 0,000 0,07606898 0,10637465 ! organic cation transport GO:0015695 32 17 0,000 0,07606898 0,1063138 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,07606898 0,10625301 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,07606898 0,10619229 ! forebrain development GO:0030900 210 98 1,000 0,07627113 0,10641369 ! regulation of nucleotide metabolic process GO:0006140 197 98 1,000 0,07627113 0,10635295 ! positive regulation of protein complex assembly GO:0031334 34 18 0,000 0,08036004 0,11199063 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,08036004 0,11192679 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,08036004 0,11186301 ! limbic system development GO:0021761 40 18 0,000 0,08036004 0,11179931 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,08036004 0,11173568 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,08036004 0,11167212 ! adult walking behavior GO:0007628 36 18 0,000 0,08036004 0,11160863 ! patterning of blood vessels GO:0001569 43 18 0,000 0,08036004 0,11154522 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,08036004 0,11148188 ! centrosome cycle GO:0007098 26 18 0,000 0,08036004 0,11141861 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,08036004 0,11135541 ! epidermis morphogenesis GO:0048730 43 18 0,000 0,08036004 0,11129228 ! glycine metabolic process GO:0006544 30 18 0,000 0,08036004 0,11122923 ! glutamine metabolic process GO:0006541 29 18 0,000 0,08036004 0,11116624 ! response to retinoic acid GO:0032526 31 18 0,000 0,08036004 0,11110333 ! cell-substrate junction assembly GO:0007044 56 18 0,000 0,08036004 0,11104049 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,08036004 0,11097772 ! DNA integration GO:0015074 32 18 0,000 0,08036004 0,11091502 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,08036004 0,11085239 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,08036004 0,11078983 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,08036004 0,11072734 ! neural crest cell migration GO:0001755 41 18 0,000 0,08036004 0,11066493 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,08036004 0,11060258 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,08036004 0,11054031 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,08036004 0,1104781 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,08036004 0,11041596 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,08036004 0,1103539 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,08036004 0,1102919 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,08036004 0,11022997 ! detection of bacterium GO:0016045 22 18 0,000 0,08036004 0,11016812 ! nerve development GO:0021675 34 18 0,000 0,08036004 0,11010633 ! defense response to virus GO:0051607 43 18 0,000 0,08036004 0,11004461 ! microspike assembly GO:0030035 46 18 0,000 0,08036004 0,10998296 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,08036004 0,10992138 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,0846313 0,11569908 ! positive regulation of translation GO:0045727 31 19 0,000 0,0846313 0,11563437 ! negative regulation of defense response GO:0031348 27 19 0,000 0,0846313 0,11556974 ! G1 phase of mitotic cell cycle GO:0000080 39 19 0,000 0,0846313 0,11550517 ! neuron maturation GO:0042551 46 19 0,000 0,0846313 0,11544068 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,0846313 0,11537626 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 0,0846313 0,11531191 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,0846313 0,11524764 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,0846313 0,11518343 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,0846313 0,1151193 ! inositol metabolic process GO:0006020 33 19 0,000 0,0846313 0,11505524 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,0846313 0,11499124 ! memory GO:0007613 34 19 0,000 0,0846313 0,11492732 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,0846313 0,11486348 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,0846313 0,1147997 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,0846313 0,11473599 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,0846313 0,11467236 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 0,000 0,0846313 0,11460879 ! cerebral cortex development GO:0021987 40 19 0,000 0,0846313 0,11454529 ! pigmentation during development GO:0048066 42 19 0,000 0,0846313 0,11448187 ! response to vitamin A GO:0033189 32 19 0,000 0,0846313 0,11441852 ! heme metabolic process GO:0042168 40 19 0,000 0,0846313 0,11435523 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,0846313 0,11429202 ! response to fungus GO:0009620 26 19 0,000 0,0846313 0,11422887 ! peptide cross-linking GO:0018149 39 19 0,000 0,0846313 0,1141658 ! protein export from nucleus GO:0006611 40 19 0,000 0,0846313 0,11410279 ! heart process GO:0003015 32 19 0,000 0,0846313 0,11403986 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,0846313 0,11397699 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,0846313 0,11391419 ! visual learning GO:0008542 38 19 0,000 0,0846313 0,11385146 ! cellular pigmentation GO:0033059 37 19 0,000 0,0846313 0,1137888 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,0846313 0,11372621 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,0846313 0,11366369 ! vitamin transport GO:0051180 31 19 0,000 0,0846313 0,11360124 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,0846313 0,11353886 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,0846313 0,11347654 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,0846313 0,11341429 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,0846313 0,11335211 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,0846313 0,11329 ! cilium assembly GO:0042384 38 19 0,000 0,0846313 0,11322796 ! peptide hormone secretion GO:0030072 32 19 0,000 0,0846313 0,11316599 ! protein secretion GO:0009306 45 20 0,000 0,08888283 0,11878597 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,08888283 0,11872103 ! positive regulation of ossification GO:0045778 50 20 0,000 0,08888283 0,11865615 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,08888283 0,11859135 ! skin development GO:0043588 42 20 0,000 0,08888283 0,11852662 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,08888283 0,11846195 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,08888283 0,11839736 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,08888283 0,11833284 ! response to vitamin GO:0033273 36 20 0,000 0,08888283 0,11826839 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,08888283 0,11820401 ! bile acid metabolic process GO:0008206 34 20 0,000 0,08888283 0,1181397 ! response to alkaloid GO:0043279 38 20 0,000 0,08888283 0,11807545 ! retinoid metabolic process GO:0001523 34 20 0,000 0,08888283 0,11801128 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 40 20 0,000 0,08888283 0,11794718 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,08888283 0,11788315 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,08888283 0,11781919 GO:0032392|DNA geometric change, ! cellular response to unfolded protein GO:0034620 35 20 0,000 0,08888283 0,11775529 GO:0030968|endoplasmic reticulum unfolded protein response, ! actin filament bundle formation GO:0051017 47 20 0,000 0,08888283 0,11769147 ! body fluid secretion GO:0007589 33 20 0,000 0,08888283 0,11762771 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,08888283 0,11756403 ! peptide secretion GO:0002790 38 20 0,000 0,08888283 0,11750041 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,08888283 0,11743686 ! regulation of fatty acid metabolic process GO:0019217 45 20 0,000 0,08888283 0,11737338 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,08888283 0,11730997 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,08888283 0,11724663 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,08888283 0,11718336 ! cell-cell junction organization GO:0045216 43 20 0,000 0,08888283 0,11712015 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 0,000 0,08888283 0,11705701 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,08888283 0,11699394 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,08888283 0,11693094 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,08888283 0,11686801 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,08888283 0,11680514 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,08888283 0,11674234 ! negative regulation of translation GO:0017148 32 20 0,000 0,08888283 0,11667961 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,08888283 0,11661695 ! regulation of cell killing GO:0031341 46 21 0,000 0,09311474 0,12210377 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,09311474 0,12203826 ! hormone secretion GO:0046879 39 21 0,000 0,09311474 0,12197282 ! cAMP metabolic process GO:0046058 41 21 0,000 0,09311474 0,12190746 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,09311474 0,12184216 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,09311474 0,12177694 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,09311474 0,12171178 ! ovarian follicle development GO:0001541 39 21 0,000 0,09311474 0,12164669 ! smooth muscle contraction GO:0006939 48 21 0,000 0,09311474 0,12158168 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,09311474 0,12151673 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,09311474 0,12145185 ! plasma membrane fusion GO:0045026 33 21 0,000 0,09311474 0,12138704 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,09311474 0,1213223 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,09311474 0,12125763 GO:0006692|prostanoid metabolic process, ! regulation of vasoconstriction GO:0019229 40 21 0,000 0,09311474 0,12119303 ! sensory perception of pain GO:0019233 33 21 0,000 0,09311474 0,1211285 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,09311474 0,12106403 ! diencephalon development GO:0021536 36 21 0,000 0,09311474 0,12099964 ! collagen fibril organization GO:0030199 62 21 0,000 0,09311474 0,12093531 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,09311474 0,12087105 ! negative regulation of intracellular transport GO:0032387 44 21 0,000 0,09311474 0,12080686 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,09311474 0,12074274 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 0,09311474 0,12067868 ! collagen catabolic process GO:0030574 29 21 0,000 0,09311474 0,12061469 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,09311474 0,12055078 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,09311474 0,12048693 ! sperm-egg recognition GO:0035036 23 21 0,000 0,09311474 0,12042314 ! actin filament-based movement GO:0030048 47 21 0,000 0,09311474 0,12035943 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 0,000 0,09311474 0,12029578 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,09732711 0,12567132 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,09732711 0,12560493 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,09732711 0,12553862 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,09732711 0,12547237 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,09732711 0,12540619 ! microtubule-based transport GO:0010970 59 22 0,000 0,09732711 0,12534008 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,09732711 0,12527405 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 0,000 0,09732711 0,12520808 ! vacuolar transport GO:0007034 41 22 0,000 0,09732711 0,12514218 ! central nervous system neuron development GO:0021954 47 22 0,000 0,09732711 0,12507635 ! fucose metabolic process GO:0006004 44 22 0,000 0,09732711 0,12501059 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,09732711 0,1249449 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,09732711 0,12487927 ! ureteric bud development GO:0001657 50 22 0,000 0,09732711 0,12481372 ! cell aging GO:0007569 48 22 0,000 0,09732711 0,12474824 ! stem cell differentiation GO:0048863 57 22 0,000 0,09732711 0,12468282 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,09732711 0,12461747 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 0,09732711 0,12455219 ! cytolysis GO:0019835 27 22 0,000 0,09732711 0,12448698 ! renal system process GO:0003014 42 22 0,000 0,09732711 0,12442184 ! vasodilation GO:0042311 40 22 0,000 0,09732711 0,12435677 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,09732711 0,12429176 ! G1 phase GO:0051318 44 22 0,000 0,09732711 0,12422682 ! detection of chemical stimulus GO:0009593 42 22 0,000 0,09732711 0,12416195 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,09732711 0,12409715 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,09732711 0,12403241 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,09732711 0,12396775 ! sarcomere organization GO:0045214 32 22 0,000 0,09732711 0,12390315 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,09732711 0,12383861 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,09732711 0,12377415 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,09732711 0,12370975 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,09732711 0,12364542 ! gut development GO:0048565 44 22 0,000 0,09732711 0,12358115 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,09732711 0,12351695 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,09732711 0,12345282 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,10152004 0,12870444 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,10152004 0,12863768 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,10152004 0,128571 ! gluconeogenesis GO:0006094 38 23 0,000 0,10152004 0,12850438 ! glycerol metabolic process GO:0006071 40 23 0,000 0,10152004 0,12843783 ! viral genome replication GO:0019079 44 23 0,000 0,10152004 0,12837135 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,10152004 0,12830494 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,10152004 0,1282386 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,10152004 0,12817233 ! regeneration GO:0031099 42 23 0,000 0,10152004 0,12810612 ! axis specification GO:0009798 43 23 0,000 0,10152004 0,12803998 ! visual behavior GO:0007632 46 23 0,000 0,10152004 0,12797392 ! regulation of DNA recombination GO:0000018 51 23 0,000 0,10152004 0,12790792 ! response to ethanol GO:0045471 47 23 0,000 0,10152004 0,12784198 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,10152004 0,12777612 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,10152004 0,12771032 ! peroxisome organization GO:0007031 43 23 0,000 0,10152004 0,1276446 ! lysosome organization GO:0007040 47 23 0,000 0,10152004 0,12757894 ! vesicle targeting GO:0006903 49 23 0,000 0,10152004 0,12751334 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,10152004 0,12744782 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,10152004 0,12738236 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,10152004 0,12731697 ! fatty acid transport GO:0015908 47 23 0,000 0,10152004 0,12725164 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,10152004 0,12718638 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,10152004 0,12712119 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,10152004 0,12705607 ! hormone transport GO:0009914 41 23 0,000 0,10152004 0,12699101 ! cell-cell recognition GO:0009988 28 23 0,000 0,10152004 0,12692602 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,10152004 0,1268611 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,10152004 0,12679624 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,10152004 0,12673145 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,1056936 0,13187409 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,1056936 0,13180677 GO:0016444|somatic cell DNA recombination, ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,1056936 0,13173952 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,1056936 0,13167235 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,1056936 0,13160523 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,1056936 0,13153819 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 0,1056936 0,13147122 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,1056936 0,13140431 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,1056936 0,13133747 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,1056936 0,1312707 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,1056936 0,131204 GO:0042278|purine nucleoside metabolic process, ! positive regulation of cytoskeleton organization GO:0051495 52 24 0,000 0,1056936 0,13113736 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,1056936 0,1310708 GO:0051693|actin filament capping, ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,1056936 0,1310043 GO:0002708|positive regulation of lymphocyte mediated immunity, ! leukotriene metabolic process GO:0006691 47 24 0,000 0,1056936 0,13093786 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,1056936 0,1308715 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,1056936 0,1308052 ! membrane depolarization GO:0051899 45 24 0,000 0,1056936 0,13073897 ! pallium development GO:0021543 56 24 0,000 0,1056936 0,13067281 ! oogenesis GO:0048477 44 24 0,000 0,1056936 0,13060671 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,1056936 0,13054068 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,1056936 0,13047472 ! platelet activation GO:0030168 41 24 0,000 0,1056936 0,13040882 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,1056936 0,13034299 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,1056936 0,13027723 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,1056936 0,13021153 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,1056936 0,1301459 ! regulation of amine transport GO:0051952 41 24 0,000 0,1056936 0,13008034 ! myeloid leukocyte differentiation GO:0002573 46 25 0,000 0,1098479 0,13512508 ! leukocyte adhesion GO:0007159 55 25 0,000 0,1098479 0,13505708 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,1098479 0,13498914 ! phototransduction GO:0007602 37 25 0,000 0,1098479 0,13492127 ! keratinization GO:0031424 37 25 0,000 0,1098479 0,13485347 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 0,000 0,1098479 0,13478574 ! vacuole organization GO:0007033 49 25 0,000 0,1098479 0,13471808 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,1098479 0,13465048 ! negative regulation of DNA replication GO:0008156 45 25 0,000 0,1098479 0,13458295 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,1098479 0,13451549 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,1098479 0,1344481 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,1098479 0,13438078 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,1098479 0,13431352 ! immunoglobulin production GO:0002377 62 25 0,000 0,1098479 0,13424633 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,1098479 0,13417921 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,1098479 0,13411215 ! liver development GO:0001889 55 25 0,000 0,1098479 0,13404516 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,11398301 0,13902171 ! initiation of viral infection GO:0019059 60 26 0,000 0,11398301 0,13895234 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,11398301 0,13888304 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,11398301 0,13881381 ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,11398301 0,13874464 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,11398301 0,13867554 GO:0006479|protein amino acid methylation, ! microtubule organizing center organization GO:0031023 42 26 0,000 0,11398301 0,13860652 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,11398301 0,13853756 ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,11398301 0,13846867 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,11398301 0,13839985 ! digestive system process GO:0022600 49 26 0,000 0,11398301 0,13833109 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,11398301 0,13826241 ! regulation of cellular ketone metabolic process GO:0010565 51 26 0,000 0,11398301 0,13819379 ! osteoblast differentiation GO:0001649 63 26 0,000 0,11398301 0,13812524 ! neural crest cell development GO:0014032 59 26 0,000 0,11398301 0,13805676 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,11398301 0,13798835 ! negative regulation of cell development GO:0010721 83 26 0,000 0,11398301 0,13792001 GO:0050768|negative regulation of neurogenesis, ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,11398301 0,13785173 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,11398301 0,13778352 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,11398301 0,13771538 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,11398301 0,1376473 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,11398301 0,1375793 ! regulation of blood coagulation GO:0030193 46 26 0,000 0,11398301 0,13751135 ! regulation of osteoblast differentiation GO:0045667 68 26 0,000 0,11398301 0,13744348 ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,11398301 0,13737568 ! blastocyst development GO:0001824 50 26 0,000 0,11398301 0,13730794 ! telomere organization GO:0032200 46 26 0,000 0,11398301 0,13724026 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,11398301 0,13717266 ! alditol metabolic process GO:0019400 44 26 0,000 0,11398301 0,13710512 ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,11398301 0,13703764 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,11398301 0,13697024 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,11809903 0,14184657 ! embryonic pattern specification GO:0009880 49 27 0,000 0,11809903 0,14177687 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,11809903 0,14170724 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,11809903 0,14163767 ! positive regulation of cell projection organization GO:0031346 66 27 0,000 0,11809903 0,14156817 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,11809903 0,14149874 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,11809903 0,14142938 ! iron ion transport GO:0006826 65 27 0,000 0,11809903 0,14136008 ! superoxide metabolic process GO:0006801 41 27 0,000 0,11809903 0,14129086 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,11809903 0,1412217 ! mitochondrial membrane organization GO:0007006 60 27 0,000 0,11809903 0,14115261 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,11809903 0,14108358 ! response to toxin GO:0009636 49 27 0,000 0,11809903 0,14101463 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,11809903 0,14094574 ! leukocyte proliferation GO:0070661 59 27 0,000 0,11809903 0,14087692 GO:0032943|mononuclear cell proliferation, ! neuron fate commitment GO:0048663 52 28 0,000 0,12219604 0,14569299 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,12219604 0,14562192 ! vesicle docking GO:0048278 55 28 0,000 0,12219604 0,14555092 ! circadian rhythm GO:0007623 56 28 0,000 0,12219604 0,14547999 ! fat cell differentiation GO:0045444 57 28 0,000 0,12219604 0,14540913 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,12219604 0,14533833 ! sperm motility GO:0030317 37 28 0,000 0,12219604 0,14526761 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,12219604 0,14519695 ! base-excision repair GO:0006284 41 28 0,000 0,12219604 0,14512637 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,12219604 0,14505585 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,12219604 0,1449854 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,12219604 0,14491502 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,12219604 0,1448447 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,12219604 0,14477446 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,12219604 0,14470428 ! glutathione metabolic process GO:0006749 42 28 0,000 0,12219604 0,14463417 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,12219604 0,14456413 ! lipid oxidation GO:0034440 48 28 0,000 0,12219604 0,14449416 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,12219604 0,14442426 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,12219604 0,14435442 ! translational initiation GO:0006413 66 29 0,000 0,12627414 0,14909992 ! cellular iron ion homeostasis GO:0006879 57 29 0,000 0,12627414 0,14902789 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,12627414 0,14895593 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,12627414 0,14888404 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,12627414 0,14881222 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,12627414 0,14874047 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,12627414 0,14866878 ! synaptogenesis GO:0007416 46 29 0,000 0,12627414 0,14859717 ! negative regulation of neuron differentiation GO:0045665 46 29 0,000 0,12627414 0,14852563 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,12627414 0,14845415 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,12627414 0,14838274 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,12627414 0,14831141 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,1303334 0,15300553 ! phenol metabolic process GO:0018958 56 30 0,000 0,1303334 0,15293204 ! negative regulation of protein complex assembly GO:0031333 68 30 0,000 0,1303334 0,15285862 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,1303334 0,15278527 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,1303334 0,15271199 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,1303334 0,15263879 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,1303334 0,15256565 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,1303334 0,15249258 ! acute-phase response GO:0006953 50 30 0,000 0,1303334 0,15241958 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,1303334 0,15234665 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,1303334 0,1522738 ! myofibril assembly GO:0030239 50 30 0,000 0,1303334 0,15220101 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 72 30 0,000 0,1303334 0,15212829 ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,1303334 0,15205564 GO:0002764|immune response-regulating signal transduction, ! cell fate determination GO:0001709 64 30 0,000 0,1303334 0,15198306 ! phospholipid transport GO:0015914 65 30 0,000 0,1303334 0,15191055 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,1303334 0,15183811 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,1303334 0,15176573 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,1303334 0,15169343 ! tissue homeostasis GO:0001894 50 30 0,000 0,1303334 0,15162119 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 52 30 0,000 0,1303334 0,15154903 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,13437392 0,15617293 ! zinc ion transport GO:0006829 54 31 0,000 0,13437392 0,15609867 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,13437392 0,15602447 ! cell junction assembly GO:0034329 85 31 0,000 0,13437392 0,15595035 ! regulation of innate immune response GO:0045088 57 31 0,000 0,13437392 0,1558763 ! ovulation cycle process GO:0022602 55 31 0,000 0,13437392 0,15580232 ! peptide transport GO:0015833 60 31 0,000 0,13437392 0,15572841 ! male gonad development GO:0008584 56 31 0,000 0,13437392 0,15565457 ! iron ion homeostasis GO:0055072 60 31 0,000 0,13437392 0,1555808 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,13437392 0,1555071 ! detection of light stimulus GO:0009583 44 31 0,000 0,13437392 0,15543347 ! natural killer cell activation GO:0030101 50 31 0,000 0,13437392 0,15535991 ! cofactor catabolic process GO:0051187 54 31 0,000 0,13437392 0,15528642 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,13437392 0,155213 ! eye morphogenesis GO:0048592 65 31 0,000 0,13437392 0,15513965 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,13437392 0,15506637 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,13839578 0,15963215 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,13839578 0,15955682 ! collagen metabolic process GO:0032963 49 32 0,000 0,13839578 0,15948156 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,13839578 0,15940636 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,13839578 0,15933124 ! metanephros development GO:0001656 81 32 0,000 0,13839578 0,15925619 ! response to mechanical stimulus GO:0009612 60 32 0,000 0,13839578 0,15918121 ! mesoderm formation GO:0001707 73 32 0,000 0,13839578 0,15910631 ! hexose biosynthetic process GO:0019319 53 32 0,000 0,13839578 0,15903147 ! ovulation cycle GO:0042698 57 32 0,000 0,13839578 0,1589567 ! BMP signaling pathway GO:0030509 71 32 0,000 0,13839578 0,158882 ! hindbrain development GO:0030902 65 32 0,000 0,13839578 0,15880737 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,13839578 0,15873282 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,13839578 0,15865833 ! gene silencing GO:0016458 71 32 0,000 0,13839578 0,15858391 ! regulation of pH GO:0006885 56 33 0,000 0,14239907 0,16309467 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,14239907 0,16301824 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,14239907 0,16294189 GO:0055092|sterol homeostasis, ! pigment biosynthetic process GO:0046148 73 33 0,000 0,14239907 0,1628656 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,14239907 0,16278939 ! triglyceride metabolic process GO:0006641 46 33 0,000 0,14239907 0,16271325 ! response to ionizing radiation GO:0010212 74 33 0,000 0,14239907 0,16263718 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,14239907 0,16256118 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,14239907 0,16248525 ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,14239907 0,1624094 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,14239907 0,16233361 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,14638387 0,16679841 ! glial cell differentiation GO:0010001 67 34 0,000 0,14638387 0,16672065 ! post-embryonic development GO:0009791 76 34 0,000 0,14638387 0,16664296 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,14638387 0,16656534 ! cholesterol transport GO:0030301 62 34 0,000 0,14638387 0,1664878 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,14638387 0,16641032 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,14638387 0,16633292 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,14638387 0,1662556 ! formation of primary germ layer GO:0001704 76 34 0,000 0,14638387 0,16617834 ! cell fate specification GO:0001708 56 34 0,000 0,14638387 0,16610116 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,14638387 0,16602404 ! adult locomotory behavior GO:0008344 62 34 0,000 0,14638387 0,165947 ! DNA damage checkpoint GO:0000077 78 35 0,000 0,15035026 0,17036442 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,15035026 0,17028544 ! negative regulation of secretion GO:0051048 68 35 0,000 0,15035026 0,17020653 ! negative regulation of DNA metabolic process GO:0051053 65 35 0,000 0,15035026 0,17012769 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,15035026 0,17004893 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,15035026 0,16997024 ! membrane docking GO:0022406 69 35 0,000 0,15035026 0,16989162 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,15035026 0,16981308 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,15035026 0,16973461 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,15035026 0,16965621 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,15035026 0,16957788 ! ceramide metabolic process GO:0006672 72 35 0,000 0,15035026 0,16949963 ! telencephalon development GO:0021537 81 35 0,000 0,15035026 0,16942144 ! sterol transport GO:0015918 63 35 0,000 0,15035026 0,16934333 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,15035026 0,16926529 ! vesicle localization GO:0051648 70 35 0,000 0,15035026 0,16918733 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,15429834 0,17355011 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,15429834 0,17347024 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,15429834 0,17339045 ! positive regulation of cell development GO:0010720 85 36 0,000 0,15429834 0,17331073 ! protein targeting to membrane GO:0006612 75 36 0,000 0,15429834 0,17323108 ! negative regulation of hydrolase activity GO:0051346 66 36 0,000 0,15429834 0,17315151 ! aerobic respiration GO:0009060 56 36 0,000 0,15429834 0,17307201 ! cytokine production GO:0001816 68 36 0,000 0,15429834 0,17299258 ! embryonic organ development GO:0048568 67 36 0,000 0,15429834 0,17291323 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,15429834 0,17283395 ! monosaccharide biosynthetic process GO:0046364 57 36 0,000 0,15429834 0,17275474 ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,15822818 0,17707349 ! odontogenesis GO:0042476 74 37 0,000 0,15822818 0,17699242 ! actomyosin structure organization GO:0031032 68 37 0,000 0,15822818 0,17691141 ! cell junction organization GO:0034330 96 37 0,000 0,15822818 0,17683048 ! female gonad development GO:0008585 71 37 0,000 0,15822818 0,17674963 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,15822818 0,17666885 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,16213987 0,18095372 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,16213987 0,18087109 ! organic anion transport GO:0015711 82 38 0,000 0,16213987 0,18078854 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,16213987 0,18070606 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,16213987 0,18062366 ! neutral lipid metabolic process GO:0006638 54 38 0,000 0,16213987 0,18054134 GO:0006639|acylglycerol metabolic process, ! DNA integrity checkpoint GO:0031570 82 38 0,000 0,16213987 0,18045909 ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,16213987 0,18037691 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,16213987 0,18029481 ! spermatid development GO:0007286 69 38 0,000 0,16213987 0,18021278 ! pigment metabolic process GO:0042440 87 38 0,000 0,16213987 0,18013083 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,16603349 0,18437264 ! mitotic cell cycle checkpoint GO:0007093 76 39 0,000 0,16603349 0,18428887 ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,16603349 0,18420518 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,16603349 0,18412157 ! erythrocyte homeostasis GO:0034101 75 39 0,000 0,16603349 0,18403803 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,16603349 0,18395456 ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,16603349 0,18387117 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,16990912 0,18807793 GO:0006956|complement activation, ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,16990912 0,18799275 ! learning GO:0007612 82 40 0,000 0,16990912 0,18790765 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,16990912 0,18782262 GO:0046660|female sex differentiation, ! lipid homeostasis GO:0055088 75 40 0,000 0,16990912 0,18773767 ! mismatch repair GO:0006298 58 40 0,000 0,16990912 0,1876528 ! glycerol ether metabolic process GO:0006662 57 40 0,000 0,16990912 0,187568 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,16990912 0,18748328 ! RNA export from nucleus GO:0006405 61 41 0,000 0,17376686 0,19165347 ! mRNA catabolic process GO:0006402 79 41 0,000 0,17376686 0,19156698 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,17376686 0,19148058 ! regulation of hormone secretion GO:0046883 69 41 0,000 0,17376686 0,19139424 ! establishment or maintenance of cell polarity GO:0007163 96 41 0,000 0,17376686 0,19130799 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,17376686 0,19122182 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,17376686 0,19113572 ! gliogenesis GO:0042063 91 41 0,000 0,17376686 0,1910497 ! feeding behavior GO:0007631 69 41 0,000 0,17376686 0,19096376 ! multicellular organismal metabolic process GO:0044236 64 41 0,000 0,17376686 0,19087789 ! mesenchymal cell development GO:0014031 94 41 0,000 0,17376686 0,19079211 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! monovalent inorganic cation homeostasis GO:0055067 72 41 0,000 0,17376686 0,19070639 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,17376686 0,19062076 GO:0015986|ATP synthesis coupled proton transport, ! spermatid differentiation GO:0048515 73 41 0,000 0,17376686 0,1905352 ! RNA modification GO:0009451 64 41 0,000 0,17376686 0,19044972 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,17760677 0,19457101 ! ear morphogenesis GO:0042471 64 42 0,000 0,17760677 0,19448379 ! organic ether metabolic process GO:0018904 59 42 0,000 0,17760677 0,19439666 ! alcohol biosynthetic process GO:0046165 65 42 0,000 0,17760677 0,1943096 ! T cell differentiation GO:0030217 93 42 0,000 0,17760677 0,19422263 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,17760677 0,19413572 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,17760677 0,1940489 ! regulation of protein secretion GO:0050708 77 42 0,000 0,17760677 0,19396216 ! dorsal/ventral pattern formation GO:0009953 75 42 0,000 0,17760677 0,19387549 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,17760677 0,1937889 ! epithelial cell differentiation GO:0030855 83 43 0,000 0,18142895 0,19787095 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,18142895 0,19778265 ! regulation of tube size GO:0035150 76 43 0,000 0,18142895 0,19769443 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,18142895 0,1976063 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,18142895 0,19751824 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,18142895 0,19743025 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,18142895 0,19734235 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,18142895 0,19725453 ! ion transmembrane transport GO:0034220 79 43 0,000 0,18142895 0,19716678 ! regulation of myeloid cell differentiation GO:0045637 105 43 0,000 0,18142895 0,19707911 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,18523347 0,20112238 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 0,000 0,18523347 0,20103303 ! striated muscle contraction GO:0006941 85 44 0,000 0,18523347 0,20094377 ! phagocytosis GO:0006909 105 44 0,000 0,18523347 0,20085458 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,18523347 0,20076547 ! double-strand break repair GO:0006302 85 44 0,000 0,18523347 0,20067643 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,18902041 0,20468833 ! branching morphogenesis of a tube GO:0048754 102 45 0,000 0,18902041 0,20459763 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,18902041 0,20450702 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! keratinocyte differentiation GO:0030216 81 45 0,000 0,18902041 0,20441649 ! B cell differentiation GO:0030183 124 45 0,000 0,18902041 0,20432605 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,18902041 0,20423568 ! female gamete generation GO:0007292 71 45 0,000 0,18902041 0,20414539 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,18902041 0,20405518 ! polyol metabolic process GO:0019751 77 45 0,000 0,18902041 0,20396505 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,19278986 0,20794067 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,19278986 0,20784891 ! glycolysis GO:0006096 71 46 0,000 0,19278986 0,20775722 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,19278986 0,20766562 ! pigmentation GO:0043473 103 46 0,000 0,19278986 0,2075741 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,19654189 0,21152063 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,20027659 0,21544505 ! mitochondrial transport GO:0006839 94 48 0,000 0,20027659 0,21535022 ! regulation of JAK-STAT cascade GO:0046425 76 48 0,000 0,20027659 0,21525548 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 0,000 0,20027659 0,21516082 ! male sex differentiation GO:0046661 93 48 0,000 0,20027659 0,21506625 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,20027659 0,21497175 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,20027659 0,21487734 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,20027659 0,21478302 ! response to calcium ion GO:0051592 94 49 0,000 0,20399403 0,21867373 ! detection of stimulus involved in sensory perception GO:0050906 75 49 0,000 0,20399403 0,21857782 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,20399403 0,21848199 ! JNK cascade GO:0007254 106 49 0,000 0,20399403 0,21838625 ! protein homooligomerization GO:0051260 84 49 0,000 0,20399403 0,21829059 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,2076943 0,22215288 ! regulation of ossification GO:0030278 123 50 0,000 0,2076943 0,22205566 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,2076943 0,22195852 GO:0019724|B cell mediated immunity, ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,2076943 0,22186147 ! epidermal cell differentiation GO:0009913 87 50 0,000 0,2076943 0,2217645 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,2076943 0,22166762 ! regulation of cell projection organization GO:0031344 135 51 0,000 0,21137747 0,22550007 ! viral infectious cycle GO:0019058 104 51 0,000 0,21137747 0,22540164 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,21137747 0,2253033 ! peptide metabolic process GO:0006518 80 51 0,000 0,21137747 0,22520504 ! detection of abiotic stimulus GO:0009582 80 51 0,000 0,21137747 0,22510687 ! response to estrogen stimulus GO:0043627 98 52 0,000 0,21504362 0,22891136 ! Notch signaling pathway GO:0007219 111 52 0,000 0,21504362 0,22881166 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,21504362 0,22871205 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,21504362 0,22861252 ! excretion GO:0007588 87 52 0,000 0,21504362 0,22851308 ! DNA-dependent DNA replication GO:0006261 82 52 0,000 0,21504362 0,22841373 ! morphogenesis of a branching structure GO:0001763 116 52 0,000 0,21504362 0,22831446 ! amino acid activation GO:0043038 98 52 0,000 0,21504362 0,22821528 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,21869283 0,23198723 ! inner ear development GO:0048839 89 53 0,000 0,21869283 0,23188654 ! chromatin remodeling GO:0006338 122 53 0,000 0,21869283 0,23178594 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,21869283 0,23168543 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,21869283 0,231585 ! regulation of neuron apoptosis GO:0043523 117 53 0,000 0,21869283 0,23148466 ! regulation of translational initiation GO:0006446 87 54 0,000 0,22232518 0,23522755 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,22232518 0,23512572 ! neuromuscular process GO:0050905 107 54 0,000 0,22232518 0,23502398 ! embryonic skeletal system development GO:0048706 101 54 0,000 0,22232518 0,23492233 ! membrane fusion GO:0006944 122 54 0,000 0,22232518 0,23482076 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,22232518 0,23471928 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,22232518 0,23461789 ! RNA catabolic process GO:0006401 103 55 0,000 0,22594074 0,23833041 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,22594074 0,23822755 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,22594074 0,23812478 ! cell recognition GO:0008037 98 55 0,000 0,22594074 0,2380221 ! cell maturation GO:0048469 107 55 0,000 0,22594074 0,2379195 ! regulation of protein polymerization GO:0032271 117 55 0,000 0,22594074 0,23781699 ! glucose catabolic process GO:0006007 88 56 0,000 0,2295396 0,24150097 ! chloride transport GO:0006821 102 57 0,000 0,23312182 0,24516428 ! nucleotide-excision repair GO:0006289 91 57 0,000 0,23312182 0,24505879 ! regulation of actin filament length GO:0030832 118 58 0,000 0,23668749 0,24870002 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,23668749 0,2485931 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,23668749 0,24848627 ! gastrulation GO:0007369 122 58 0,000 0,23668749 0,24837953 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,23668749 0,24827288 ! nuclear export GO:0051168 110 59 0,000 0,24023668 0,25188765 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,24376947 0,25548212 ! regulation of endocytosis GO:0030100 104 60 0,000 0,24376947 0,25537256 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,24376947 0,2552631 ! adult behavior GO:0030534 104 60 0,000 0,24376947 0,25515373 ! kidney development GO:0001822 133 60 0,000 0,24376947 0,25504446 ! positive regulation of secretion GO:0051047 110 61 0,000 0,24728593 0,25861281 ! regulation of cellular component size GO:0032535 125 61 0,000 0,24728593 0,25850215 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,24728593 0,25839159 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,24728593 0,25828111 ! cytokine-mediated signaling pathway GO:0019221 112 61 0,000 0,24728593 0,25817074 ! camera-type eye development GO:0043010 126 61 0,000 0,24728593 0,25806046 ! proton transport GO:0015992 117 61 0,000 0,24728593 0,25795027 ! DNA damage response, signal transduction GO:0042770 136 62 0,000 0,25078614 0,26148977 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,25078614 0,26137821 ! tRNA processing GO:0008033 102 62 0,000 0,25078614 0,26126675 ! regulation of protein complex assembly GO:0043254 132 63 0,000 0,25427016 0,26478347 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,25427016 0,26467065 ! hydrogen transport GO:0006818 121 64 0,000 0,25773809 0,26816616 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,25773809 0,268052 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,26118998 0,27152644 ! lymphocyte mediated immunity GO:0002449 122 65 0,000 0,26118998 0,27141094 ! multicellular organism reproduction GO:0032504 123 65 0,000 0,26118998 0,27129555 GO:0048609|reproductive process in a multicellular organism, ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,26118998 0,27118025 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,26118998 0,27106505 ! ear development GO:0043583 114 66 0,000 0,26462592 0,27451428 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,26462592 0,27439776 ! regulation of lipid metabolic process GO:0019216 132 66 0,000 0,26462592 0,27428134 ! gonad development GO:0008406 115 66 0,000 0,26462592 0,27416502 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,26804598 0,27759064 ! secondary metabolic process GO:0019748 125 67 0,000 0,26804598 0,27747302 ! myeloid cell differentiation GO:0030099 126 67 0,000 0,26804598 0,27735549 ! regulation of cellular response to stress GO:0080135 142 68 0,000 0,27145022 0,28075906 ! hexose catabolic process GO:0019320 113 68 0,000 0,27145022 0,28064024 ! extracellular matrix organization GO:0030198 146 68 0,000 0,27145022 0,28052153 ! detection of external stimulus GO:0009581 102 68 0,000 0,27145022 0,28040291 ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,27145022 0,2802844 ! cell projection assembly GO:0030031 138 68 0,000 0,27145022 0,28016599 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,27483873 0,2835435 ! single fertilization GO:0007338 83 69 0,000 0,27483873 0,28342381 ! cell redox homeostasis GO:0045454 114 70 0,000 0,27821157 0,28678096 ! activation of immune response GO:0002253 120 70 0,000 0,27821157 0,28666001 ! protein maturation by peptide bond cleavage GO:0051605 118 70 0,000 0,27821157 0,28653915 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,28156882 0,28987469 ! B cell activation GO:0042113 179 72 0,000 0,28491055 0,29319144 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,28491055 0,29306799 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,28491055 0,29294465 ! regulation of MAPKKK cascade GO:0043408 157 72 0,000 0,28491055 0,2928214 ! humoral immune response GO:0006959 115 73 0,000 0,28823683 0,29611547 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,28823683 0,295991 ! regulation of immune effector process GO:0002697 156 73 0,000 0,28823683 0,29586663 ! acute inflammatory response GO:0002526 118 74 0,000 0,29154773 0,29913948 ! amino acid transport GO:0006865 148 74 0,000 0,29154773 0,2990139 ! transition metal ion transport GO:0000041 143 75 0,000 0,29484332 0,30226699 ! leukocyte mediated immunity GO:0002443 136 75 0,000 0,29484332 0,3021402 ! eye development GO:0001654 155 75 0,000 0,29484332 0,30201352 ! rhythmic process GO:0048511 142 75 0,000 0,29484332 0,30188694 ! regulation of actin cytoskeleton organization GO:0032956 167 76 0,000 0,29812368 0,30511778 ! learning or memory GO:0007611 161 76 0,000 0,29812368 0,30499001 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,29812368 0,30486234 ! regulation of blood pressure GO:0008217 134 76 0,000 0,29812368 0,30473479 ! lymphocyte differentiation GO:0030098 193 76 0,000 0,29812368 0,30460734 ! neurotransmitter transport GO:0006836 142 77 0,000 0,30138886 0,30781479 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,30138886 0,30768616 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,30138886 0,30755764 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,30138886 0,30742922 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,30463895 0,31061475 ! antigen processing and presentation GO:0019882 117 78 0,000 0,30463895 0,31048517 ! fertilization GO:0009566 99 78 0,000 0,30463895 0,31035569 ! blood coagulation GO:0007596 151 79 0,000 0,30787401 0,31352072 GO:0050817|coagulation, ! regulation of actin filament-based process GO:0032970 170 79 0,000 0,30787401 0,31339008 ! steroid biosynthetic process GO:0006694 146 79 0,000 0,30787401 0,31325956 ! regulation of synaptic transmission GO:0050804 159 79 0,000 0,30787401 0,31312914 ! activation of protein kinase activity GO:0032147 170 80 0,000 0,3110941 0,31627253 ! development of primary sexual characteristics GO:0045137 143 80 0,000 0,3110941 0,31614097 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 0,000 0,31429931 0,31926537 ! exocytosis GO:0006887 153 83 0,000 0,32066533 0,32559659 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,32066533 0,32546132 ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,32066533 0,32532616 ! inorganic anion transport GO:0015698 156 83 0,000 0,32066533 0,32519111 ! T cell activation GO:0042110 189 84 0,000 0,32382627 0,32826041 ! response to nutrient GO:0007584 135 84 0,000 0,32382627 0,32812425 ! digestion GO:0007586 130 84 0,000 0,32382627 0,32798822 ! hemostasis GO:0007599 165 85 0,000 0,32697259 0,33103773 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,32697259 0,3309006 ! regulation of transmission of nerve impulse GO:0051969 167 85 0,000 0,32697259 0,33076358 ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,33322165 0,33694557 ! alcohol catabolic process GO:0046164 142 87 0,000 0,33322165 0,33680617 ! nucleosome assembly GO:0006334 126 87 0,000 0,33322165 0,33666687 ! cellular respiration GO:0045333 143 88 0,000 0,33632452 0,33966135 ! amine biosynthetic process GO:0009309 146 88 0,000 0,33632452 0,339521 ! sensory perception of smell GO:0007608 117 88 0,000 0,33632452 0,33938076 ! chromatin assembly GO:0031497 128 88 0,000 0,33632452 0,33924063 ! cellular defense response GO:0006968 123 89 0,000 0,33941304 0,34221463 ! regulation of neurological system process GO:0031644 175 89 0,000 0,33941304 0,34207346 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,34248727 0,34502944 ! response to unfolded protein GO:0006986 139 90 0,000 0,34248727 0,34488722 ! defense response to bacterium GO:0042742 112 91 0,000 0,34554728 0,3478253 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,34859314 0,35074672 ! amine transport GO:0015837 181 93 0,000 0,3516249 0,35365156 ! vitamin metabolic process GO:0006766 153 93 0,000 0,3516249 0,35350602 ! female pregnancy GO:0007565 166 94 0,000 0,35464264 0,35639324 ! sterol metabolic process GO:0016125 166 94 0,000 0,35464264 0,3562467 ! nucleosome organization GO:0034728 143 95 0,000 0,35764642 0,3591164 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,35764642 0,35896886 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,35764642 0,35882144 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,35764642 0,35867414 ! response to protein stimulus GO:0051789 158 96 0,000 0,3606363 0,3615242 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,36361235 0,36435807 ! transcription initiation GO:0006352 171 97 0,000 0,36361235 0,36420868 ! leukocyte differentiation GO:0002521 232 98 0,000 0,36657463 0,36702534 ! mRNA transport GO:0051028 185 100 0,000 0,37245814 0,37276331 ! positive regulation of immune response GO:0050778 175 100 0,000 0,37245814 0,37261066 ! hormone metabolic process GO:0042445 171 100 0,000 0,37245814 0,37245814