pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6637-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 2,000 1,087E-06 2,614E-03 ! epithelial to mesenchymal transition GO:0001837 28 15 2,000 4,089E-06 4,919E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 3,000 6,73E-06 5,397E-03 ! protein amino acid autophosphorylation GO:0046777 141 60 3,000 8,268E-06 4,973E-03 ! negative regulation of protein kinase activity GO:0006469 130 67 3,000 1,285E-05 6,185E-03 ! negative regulation of kinase activity GO:0033673 131 68 3,000 1,363E-05 5,467E-03 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 2,000 1,369E-05 4,707E-03 ! negative regulation of transferase activity GO:0051348 140 72 3,000 1,711E-05 5,147E-03 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 2,000 2,298E-05 6,143E-03 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 4,427E-05 0,01065168 ! glial cell migration GO:0008347 11 5 1,000 4,427E-05 9,683E-03 ! regulation of sensory perception GO:0051931 7 5 1,000 4,427E-05 8,876E-03 GO:0051930|regulation of sensory perception of pain, ! androgen receptor signaling pathway GO:0030521 74 36 2,000 6,215E-05 0,0115029 ! mesenchymal cell development GO:0014031 87 40 2,000 8,548E-05 0,01469086 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! axonal fasciculation GO:0007413 18 7 1,000 9,271E-05 0,01487146 ! neuron migration GO:0001764 79 42 2,000 9,903E-05 0,01489098 ! regulation of epithelial cell proliferation GO:0050678 111 43 2,000 1,063E-04 0,01504335 ! induction of apoptosis by intracellular signals GO:0008629 93 45 2,000 1,218E-04 0,01628683 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 1,235E-04 0,0156327 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 1,000 1,235E-04 0,01485106 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 1,000 1,235E-04 0,01414387 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 2,000 1,302E-04 0,01423369 ! positive regulation of cell cycle GO:0045787 89 48 2,000 1,478E-04 0,01546572 ! regulation of mast cell proliferation GO:0070666 81 48 2,000 1,478E-04 0,01482131 ! axon extension GO:0048675 15 9 1,000 1,585E-04 0,01525443 ! keratinocyte proliferation GO:0043616 14 9 1,000 1,585E-04 0,01466772 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 1,000 1,585E-04 0,01412448 ! motor axon guidance GO:0008045 16 9 1,000 1,585E-04 0,01362003 ! regulation of leukocyte proliferation GO:0070663 88 51 2,000 1,772E-04 0,01470162 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 1,000 1,979E-04 0,01586825 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 1,979E-04 0,01535637 ! localization within membrane GO:0051668 20 10 1,000 1,979E-04 0,01487648 ! response to UV GO:0009411 104 53 2,000 1,987E-04 0,01448928 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 1,000 2,415E-04 0,01708936 ! nitric oxide metabolic process GO:0046209 15 11 1,000 2,415E-04 0,01660109 GO:0006809|nitric oxide biosynthetic process, ! regulation of B cell proliferation GO:0030888 20 12 1,000 2,894E-04 0,01934139 ! hippocampus development GO:0021766 26 12 1,000 2,894E-04 0,01881865 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 1,000 2,894E-04 0,01832342 ! positive regulation of cell growth GO:0030307 22 12 1,000 2,894E-04 0,01785359 ! negative regulation of mast cell proliferation GO:0070667 23 12 1,000 2,894E-04 0,01740725 GO:0042130|negative regulation of T cell proliferation, ! steroid hormone receptor signaling pathway GO:0030518 129 63 2,000 3,318E-04 0,01947215 ! cell-cell junction assembly GO:0007043 27 13 1,000 3,415E-04 0,01956573 ! regulation of monooxygenase activity GO:0032768 33 13 1,000 3,415E-04 0,01911071 ! negative regulation of caspase activity GO:0043154 22 14 1,000 3,979E-04 0,02175925 ! release of cytochrome c from mitochondria GO:0001836 30 14 1,000 3,979E-04 0,02127571 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 2,000 4,156E-04 0,02173801 ! positive regulation of cell size GO:0045793 27 15 1,000 4,585E-04 0,02347206 ! histone deacetylation GO:0016575 20 15 1,000 4,585E-04 0,02298305 ! synaptic transmission, cholinergic GO:0007271 24 15 1,000 4,585E-04 0,02251401 ! regulation of caspase activity GO:0043281 122 72 2,000 4,916E-04 0,02365599 ! startle response GO:0001964 28 16 1,000 5,233E-04 0,0246874 ! regulation of dephosphorylation GO:0035303 43 16 1,000 5,233E-04 0,02421265 ! positive regulation of protein import into nucleus GO:0042307 30 16 1,000 5,233E-04 0,0237558 ! neuron recognition GO:0008038 35 16 1,000 5,233E-04 0,02331588 ! negative regulation of leukocyte proliferation GO:0070664 31 16 1,000 5,233E-04 0,02289196 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! regulation of endopeptidase activity GO:0052548 125 74 2,000 5,327E-04 0,02288799 ! limbic system development GO:0021761 36 17 1,000 5,923E-04 0,0249996 ! negative regulation of peptidase activity GO:0010466 27 17 1,000 5,923E-04 0,02456858 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 1,000 5,923E-04 0,02415216 ! regulation of peptidase activity GO:0052547 134 79 2,000 6,45E-04 0,02586347 ! skin development GO:0043588 36 19 1,000 7,426E-04 0,02929174 ! cerebral cortex development GO:0021987 36 19 1,000 7,426E-04 0,02881929 ! cellular response to unfolded protein GO:0034620 33 19 1,000 7,426E-04 0,02836184 GO:0030968|endoplasmic reticulum unfolded protein response, ! neuromuscular junction development GO:0007528 34 19 1,000 7,426E-04 0,02791869 ! cell-cell junction organization GO:0045216 35 19 1,000 7,426E-04 0,02748917 ! response to unfolded protein GO:0006986 131 85 2,000 7,983E-04 0,02910181 ! protein amino acid deacetylation GO:0006476 29 20 1,000 8,24E-04 0,02959121 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 1,000 8,24E-04 0,02915604 ! apoptotic mitochondrial changes GO:0008637 41 20 1,000 8,24E-04 0,02873349 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 1,000 8,24E-04 0,02832301 ! sensory perception of pain GO:0019233 30 20 1,000 8,24E-04 0,02792409 ! negative regulation of T cell activation GO:0050868 40 20 1,000 8,24E-04 0,02753626 ! regulation of neurological system process GO:0031644 148 88 2,000 8,829E-04 0,02910027 ! response to protein stimulus GO:0051789 149 91 2,000 9,73E-04 0,0316369 ! vesicle docking during exocytosis GO:0006904 41 22 1,000 9,991E-04 0,03205124 ! positive regulation of intracellular transport GO:0032388 37 22 1,000 9,991E-04 0,03162951 ! positive regulation of B cell activation GO:0050871 38 22 1,000 9,991E-04 0,03121874 ! positive regulation of MAP kinase activity GO:0043406 160 93 2,000 1,036E-03 0,03196374 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 1,093E-03 0,03328073 ! interphase of mitotic cell cycle GO:0051329 209 95 2,000 1,102E-03 0,03314157 ! positive regulation of fibroblast proliferation GO:0048146 43 24 1,000 1,19E-03 0,03536135 ! vesicle docking GO:0048278 47 24 1,000 1,19E-03 0,03493011 ! negative regulation of phosphorylation GO:0042326 47 24 1,000 1,19E-03 0,03450927 ! pallium development GO:0021543 49 24 1,000 1,19E-03 0,03409845 ! regulation of oxidoreductase activity GO:0051341 46 24 1,000 1,19E-03 0,03369729 ! interphase GO:0051325 213 98 2,000 1,205E-03 0,0337235 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 1,000 1,292E-03 0,03573652 ! myelination GO:0042552 45 25 1,000 1,292E-03 0,03533042 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 1,000 1,292E-03 0,03493345 ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 1,292E-03 0,0345453 ! regulation of transcription factor import into nucleus GO:0042990 54 26 1,000 1,398E-03 0,03696219 ! regulation of fibroblast proliferation GO:0048145 52 27 1,000 1,508E-03 0,03943126 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 1,000 1,508E-03 0,03900727 ! response to toxin GO:0009636 47 27 1,000 1,508E-03 0,0385923 ! negative regulation of lymphocyte activation GO:0051250 53 27 1,000 1,508E-03 0,03818607 ! negative regulation of protein modification process GO:0031400 60 28 1,000 1,622E-03 0,04063944 ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 1,622E-03 0,04022047 ! respiratory gaseous exchange GO:0007585 57 29 1,000 1,739E-03 0,04270049 ! cellular response to extracellular stimulus GO:0031668 48 29 1,000 1,739E-03 0,04226917 ! membrane docking GO:0022406 61 30 1,000 1,861E-03 0,04477423 ! cell junction assembly GO:0034329 78 30 1,000 1,861E-03 0,04433092 ! ensheathment of neurons GO:0007272 57 30 1,000 1,861E-03 0,0438963 GO:0008366|axon ensheathment, ! negative regulation of leukocyte activation GO:0002695 56 30 1,000 1,861E-03 0,04347012 ! regulation of B cell activation GO:0050864 50 30 1,000 1,861E-03 0,04305214 ! regulation of protein import into nucleus GO:0042306 63 32 1,000 2,116E-03 0,048489 ! peripheral nervous system development GO:0007422 64 32 1,000 2,116E-03 0,04803156 ! adult locomotory behavior GO:0008344 59 33 1,000 2,25E-03 0,0505833 ! xenobiotic metabolic process GO:0006805 51 34 1,000 2,387E-03 0,05317438 ! regulation of synaptic plasticity GO:0048167 64 35 1,000 2,528E-03 0,05580333 ! telencephalon development GO:0021537 68 35 1,000 2,528E-03 0,05529603 ! negative regulation of hydrolase activity GO:0051346 62 35 1,000 2,528E-03 0,05479786 ! calcium-mediated signaling GO:0019722 62 35 1,000 2,528E-03 0,0543086 ! cell junction organization GO:0034330 86 36 1,000 2,673E-03 0,0569165 ! negative regulation of cell activation GO:0050866 65 36 1,000 2,673E-03 0,05641723 ! positive regulation of leukocyte proliferation GO:0070665 62 38 1,000 2,975E-03 0,06223672 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! mRNA catabolic process GO:0006402 71 39 1,000 3,131E-03 0,06494655 ! mammary gland development GO:0030879 86 39 1,000 3,131E-03 0,06439145 ! regulation of action potential in neuron GO:0019228 73 39 1,000 3,131E-03 0,06384576 ! response to xenobiotic stimulus GO:0009410 57 39 1,000 3,131E-03 0,06330924 ! gliogenesis GO:0042063 88 41 1,000 3,456E-03 0,06928547 ! regulation of T cell proliferation GO:0042129 71 41 1,000 3,456E-03 0,06871286 ! keratinocyte differentiation GO:0030216 62 41 1,000 3,456E-03 0,06814964 ! regulation of T cell differentiation GO:0045580 70 41 1,000 3,456E-03 0,06759558 ! regulation of intracellular protein transport GO:0033157 80 42 1,000 3,623E-03 0,0703069 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 1,000 4,332E-03 0,08338263 ! epidermal cell differentiation GO:0009913 68 46 1,000 4,332E-03 0,08272086 ! positive regulation of protein transport GO:0051222 72 46 1,000 4,332E-03 0,08206952 ! protein homooligomerization GO:0051260 76 47 1,000 4,518E-03 0,08493142 ! regulation of lymphocyte differentiation GO:0045619 81 48 1,000 4,708E-03 0,08781719 ! regulation of action potential GO:0001508 95 49 1,000 4,902E-03 0,09072599 ! neuromuscular process GO:0050905 99 50 1,000 5,099E-03 0,093657 ! histone modification GO:0016570 91 50 1,000 5,099E-03 0,09294747 ! negative regulation of immune system process GO:0002683 95 50 1,000 5,099E-03 0,09224862 ! regulation of angiogenesis GO:0045765 114 52 1,000 5,505E-03 0,09883933 ! positive regulation of growth GO:0045927 90 52 1,000 5,505E-03 0,09810718 ! covalent chromatin modification GO:0016569 101 52 1,000 5,505E-03 0,09738581 ! synapse organization GO:0050808 85 52 1,000 5,505E-03 0,09667496 ! RNA catabolic process GO:0006401 93 53 1,000 5,713E-03 0,09960225 ! activation of phospholipase C activity GO:0007202 103 54 1,000 5,924E-03 0,1025491 GO:0010863|positive regulation of phospholipase C activity, ! cell recognition GO:0008037 85 54 1,000 5,924E-03 0,10181661 ! positive regulation of phospholipase activity GO:0010518 104 55 1,000 6,14E-03 0,10476652 ! skeletal muscle fiber development GO:0048741 111 56 1,000 6,358E-03 0,10773474 ! muscle fiber development GO:0048747 112 57 1,000 6,581E-03 0,11072063 ! positive regulation of cell migration GO:0030335 126 57 1,000 6,581E-03 0,10995173 ! regulation of phospholipase activity GO:0010517 106 57 1,000 6,581E-03 0,10919345 ! regulation of intracellular transport GO:0032386 101 57 1,000 6,581E-03 0,10844555 ! adult behavior GO:0030534 99 58 1,000 6,806E-03 0,11140267 ! positive regulation of lipase activity GO:0060193 108 58 1,000 6,806E-03 0,11064995 ! DNA damage response, signal transduction GO:0042770 128 60 1,000 7,268E-03 0,1173665 ! regulation of protein complex assembly GO:0043254 117 61 1,000 7,504E-03 0,12037205 ! viral reproductive process GO:0022415 126 62 1,000 7,744E-03 0,12339261 ! positive regulation of cell motion GO:0051272 146 64 1,000 8,234E-03 0,13032847 ! negative regulation of cell growth GO:0030308 132 67 1,000 8,993E-03 0,14142201 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 1,000 8,993E-03 0,14050369 ! viral reproduction GO:0016032 134 68 1,000 9,253E-03 0,14363194 ! regulation of lipase activity GO:0060191 130 68 1,000 9,253E-03 0,14271122 ! negative regulation of cell size GO:0045792 134 69 1,000 9,516E-03 0,14583667 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,01058087 0,16112381 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,01058087 0,16011046 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,01058087 0,15910977 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,01058087 0,15812151 ! neuron fate determination GO:0048664 7 5 0,000 0,01058087 0,15714545 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01058087 0,15618137 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,01058087 0,15522904 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,01058087 0,15428826 ! polyol transport GO:0015791 12 5 0,000 0,01058087 0,15335881 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,01058087 0,1524405 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,01058087 0,15153311 ! response to superoxide GO:0000303 10 5 0,000 0,01058087 0,15063647 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,01058087 0,14975037 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,01058087 0,14887464 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,01058087 0,14800909 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,01058087 0,14715354 ! female meiosis GO:0007143 7 5 0,000 0,01058087 0,14630783 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,01058087 0,14547179 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,01058087 0,14464524 ! cobalt ion transport GO:0006824 11 5 0,000 0,01058087 0,14382804 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,01058087 0,14302002 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,01058087 0,14222102 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,01058087 0,1414309 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,01058087 0,14064952 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,01058087 0,13987672 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,01058087 0,13911236 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,01058087 0,13835632 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,01058087 0,13760845 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,01058087 0,13686862 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,01058087 0,1361367 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01058087 0,13541257 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,01058087 0,1346961 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,01058087 0,13398717 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 0,01058087 0,13328567 ! negative chemotaxis GO:0050919 14 5 0,000 0,01058087 0,13259147 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,01058087 0,13190447 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,01058087 0,13122455 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,01058087 0,1305516 ! behavioral response to pain GO:0048266 9 5 0,000 0,01058087 0,12988552 ! clathrin coat assembly GO:0048268 14 5 0,000 0,01058087 0,12922621 ! Notch receptor processing GO:0007220 8 5 0,000 0,01058087 0,12857355 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01058087 0,12792745 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,01058087 0,12728781 ! micturition GO:0060073 9 5 0,000 0,01058087 0,12665454 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,01058087 0,12602754 ! copulation GO:0007620 9 5 0,000 0,01058087 0,12540671 ! glial cell fate commitment GO:0021781 13 5 0,000 0,01058087 0,12479197 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,01058087 0,12418323 ! spermidine metabolic process GO:0008216 7 5 0,000 0,01058087 0,1235804 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,01058087 0,12298339 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,01058087 0,12239213 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,01058087 0,12180652 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,01058087 0,12122649 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,01058087 0,12065196 ! grooming behavior GO:0007625 6 5 0,000 0,01058087 0,12008284 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,01058087 0,11951907 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,01058087 0,11896057 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01058087 0,11840727 ! response to protozoan GO:0001562 10 5 0,000 0,01058087 0,11785909 ! positive regulation of glycolysis GO:0045821 14 5 0,000 0,01058087 0,11731596 ! lymph vessel development GO:0001945 10 5 0,000 0,01058087 0,11677781 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,01058087 0,11624458 ! endochondral ossification GO:0001958 16 5 0,000 0,01058087 0,11571619 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,01058087 0,11519259 ! parathyroid gland development GO:0060017 13 5 0,000 0,01058087 0,11467371 ! anagen GO:0042640 6 5 0,000 0,01058087 0,11415947 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,01058087 0,11364983 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,01058087 0,11314472 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,01058087 0,11264408 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,01058087 0,11214785 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,01058087 0,11165598 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,01058087 0,1111684 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,01058087 0,11068506 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,01058087 0,1102059 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,01058087 0,10973087 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,01058087 0,10925993 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,01058087 0,108793 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,01058087 0,10833005 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,01058087 0,10787103 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,01058087 0,10741588 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,01058087 0,10696455 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,01058087 0,106517 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 0,01058087 0,10607318 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,01058087 0,10563304 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,01058087 0,10519654 ! histidine catabolic process GO:0006548 6 5 0,000 0,01058087 0,10476363 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,01058087 0,10433427 ! microvillus organization GO:0032528 7 5 0,000 0,01058087 0,10390842 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 0,01058087 0,10348603 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,01058087 0,10306706 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,01058087 0,10265146 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,01058087 0,10223921 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,01058087 0,10183025 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,01058087 0,10142455 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,01058087 0,10102207 ! polyol catabolic process GO:0046174 7 5 0,000 0,01058087 0,10062278 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,01058087 0,10022662 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,01058087 0,09983358 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,01058087 0,0994436 ! muscle cell migration GO:0014812 8 5 0,000 0,01058087 0,09905666 ! mitochondrial fission GO:0000266 8 5 0,000 0,01058087 0,09867272 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,01058087 0,09829175 ! mRNA transcription GO:0009299 9 5 0,000 0,01058087 0,0979137 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,01058087 0,09753855 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,01058087 0,09716627 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,01058087 0,09679682 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,01058087 0,09643016 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,01058087 0,09606627 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,01058087 0,09570512 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,01058087 0,09534668 ! response to food GO:0032094 6 5 0,000 0,01058087 0,09499091 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,01058087 0,09463778 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,01058087 0,09428727 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,01058087 0,09393935 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01058087 0,09359398 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,01058087 0,09325115 ! forebrain neuron development GO:0021884 13 5 0,000 0,01058087 0,09291081 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,01058087 0,09257296 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,01058087 0,09223755 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,01058087 0,09190456 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01058087 0,09157397 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,01058087 0,09124574 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,01058087 0,09091987 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01058087 0,09059631 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,01058087 0,09027505 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,01058087 0,08995605 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,01058087 0,08963931 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,01058087 0,08932478 ! basic amino acid transport GO:0015802 11 5 0,000 0,01058087 0,08901246 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,01058087 0,08870231 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,01058087 0,08839431 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01058087 0,08808845 ! depyrimidination GO:0045008 10 5 0,000 0,01058087 0,0877847 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,01058087 0,08748303 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01058087 0,08718343 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,01058087 0,08688588 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,01058087 0,08659035 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 0,01058087 0,08629682 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,01058087 0,08600528 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01058087 0,0857157 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,01058087 0,08542806 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,01058087 0,08514235 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,01058087 0,08485854 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,01058087 0,08457662 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,01058087 0,08429657 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01058087 0,08401836 ! response to arsenic GO:0046685 10 5 0,000 0,01058087 0,08374198 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,01058087 0,08346742 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,01058087 0,08319465 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,01058087 0,08292366 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,01058087 0,08265442 ! response to cadmium ion GO:0046686 7 5 0,000 0,01058087 0,08238693 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,01058087 0,08212117 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,01058087 0,08185711 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,01058087 0,08159475 ! decidualization GO:0046697 11 5 0,000 0,01058087 0,08133407 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,01058087 0,08107504 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,01058087 0,08081766 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,01058087 0,08056191 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,01058087 0,08030777 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,01058087 0,08005523 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,01058087 0,07980427 ! neural tube patterning GO:0021532 7 5 0,000 0,01058087 0,07955488 ! embryonic cleavage GO:0040016 6 5 0,000 0,01058087 0,07930705 ! peroxisome fission GO:0016559 5 5 0,000 0,01058087 0,07906075 ! histone demethylation GO:0016577 10 5 0,000 0,01058087 0,07881598 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,01058087 0,07857272 ! mitotic recombination GO:0006312 9 5 0,000 0,01058087 0,07833096 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,01058087 0,07809068 ! metaphase plate congression GO:0051310 7 5 0,000 0,01058087 0,07785187 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01058087 0,07761452 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,01058087 0,07737861 ! enteric nervous system development GO:0048484 8 5 0,000 0,01058087 0,07714413 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,01058087 0,07691107 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,01058087 0,07667941 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,01058087 0,07644914 ! muscle cell proliferation GO:0033002 11 5 0,000 0,01058087 0,07622025 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,01058087 0,07599272 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,01058087 0,07576656 ! plasminogen activation GO:0031639 5 5 0,000 0,01058087 0,07554173 ! B cell homeostasis GO:0001782 13 5 0,000 0,01058087 0,07531823 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,01058087 0,07509606 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,01058087 0,07487518 ! metaphase GO:0051323 8 5 0,000 0,01058087 0,07465561 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,01058087 0,07443732 ! cellular response to nutrient GO:0031670 8 5 0,000 0,01058087 0,0742203 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,01058087 0,07400454 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,01058087 0,07379004 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,01058087 0,07357677 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,01058087 0,07336473 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,01058087 0,07315392 ! response to redox state GO:0051775 5 5 0,000 0,01058087 0,07294431 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,01058087 0,07273589 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,01058087 0,07252867 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,01058087 0,07232262 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,01058087 0,07211774 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01058087 0,07191402 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,01058087 0,07171144 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01058087 0,07151001 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,01058087 0,0713097 ! striatum development GO:0021756 9 5 0,000 0,01058087 0,07111051 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,01058087 0,07091243 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,01058087 0,07071545 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,01058087 0,07051956 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,01058087 0,07032476 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,01058087 0,07013103 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,01058087 0,06993836 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,01058087 0,06974675 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,01058087 0,06955618 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,01058087 0,06936666 ! neuroprotection GO:0043526 6 5 0,000 0,01058087 0,06917816 ! neural plate development GO:0001840 8 5 0,000 0,01058087 0,06899068 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,01058087 0,06880422 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,01058087 0,06861877 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,01058087 0,06843431 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,01058087 0,06825084 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,01058087 0,06806835 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,01058087 0,06788683 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,01058087 0,06770628 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,01058087 0,06752669 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,01058087 0,06734805 ! spindle assembly GO:0051225 6 5 0,000 0,01058087 0,06717035 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,01058087 0,06699359 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,01058087 0,06681775 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,01058087 0,06664283 ! drug metabolic process GO:0017144 6 5 0,000 0,01058087 0,06646883 ! stem cell division GO:0017145 11 5 0,000 0,01058087 0,06629574 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,01058087 0,06612354 ! organ regeneration GO:0031100 7 5 0,000 0,01058087 0,06595224 ! carnitine metabolic process GO:0009437 7 5 0,000 0,01058087 0,06578182 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,01058087 0,06561228 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,01058087 0,06544361 ! axon guidance GO:0007411 139 73 1,000 0,01060246 0,06540901 ! exocytosis GO:0006887 133 74 1,000 0,01088217 0,06696294 ! phosphoinositide-mediated signaling GO:0048015 131 75 1,000 0,01116513 0,06852886 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 0,01174074 0,07187842 ! protein oligomerization GO:0051259 139 78 1,000 0,01203335 0,07348286 ! positive regulation of phosphorylation GO:0042327 129 79 1,000 0,01232915 0,0750986 ! regulation of synaptic transmission GO:0050804 134 79 1,000 0,01232915 0,07490895 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,01268378 0,07686943 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,01268378 0,07667629 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,01268378 0,07648412 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,01268378 0,07629291 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,01268378 0,07610265 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,01268378 0,07591334 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,01268378 0,07572497 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,01268378 0,07553753 ! sleep GO:0030431 13 6 0,000 0,01268378 0,07535102 ! response to oxygen radical GO:0000305 11 6 0,000 0,01268378 0,07516543 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,01268378 0,07498075 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,01268378 0,07479697 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,01268378 0,07461409 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,01268378 0,07443211 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,01268378 0,07425101 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,01268378 0,07407079 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,01268378 0,07389144 ! forebrain regionalization GO:0021871 8 6 0,000 0,01268378 0,07371296 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,01268378 0,07353534 ! male meiosis GO:0007140 7 6 0,000 0,01268378 0,07335857 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,01268378 0,07318265 ! response to zinc ion GO:0010043 9 6 0,000 0,01268378 0,07300757 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,01268378 0,07283333 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,01268378 0,07265991 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,01268378 0,07248733 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,01268378 0,07231555 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,01268378 0,0721446 ! malate metabolic process GO:0006108 11 6 0,000 0,01268378 0,07197444 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,01268378 0,07180509 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,01268378 0,07163654 ! protein refolding GO:0042026 15 6 0,000 0,01268378 0,07146877 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,01268378 0,07130179 ! opsonization GO:0008228 8 6 0,000 0,01268378 0,07113558 ! mating behavior GO:0007617 7 6 0,000 0,01268378 0,07097015 ! neuron remodeling GO:0016322 15 6 0,000 0,01268378 0,07080549 ! erythrocyte maturation GO:0043249 7 6 0,000 0,01268378 0,07064158 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,01268378 0,07047844 ! equilibrioception GO:0050957 14 6 0,000 0,01268378 0,07031605 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,01268378 0,0701544 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,01268378 0,0699935 ! photoreceptor cell development GO:0042461 10 6 0,000 0,01268378 0,06983333 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,01268378 0,06967389 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,01268378 0,06951518 ! response to interferon-gamma GO:0034341 15 6 0,000 0,01268378 0,06935719 ! toxin metabolic process GO:0009404 11 6 0,000 0,01268378 0,06919992 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,01268378 0,06904336 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,01268378 0,0688875 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,01268378 0,06873235 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,01268378 0,0685779 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,01268378 0,06842413 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,01268378 0,06827106 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,01268378 0,06811867 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,01268378 0,06796696 ! thymic T cell selection GO:0045061 12 6 0,000 0,01268378 0,06781592 ! protein lipoylation GO:0009249 10 6 0,000 0,01268378 0,06766555 ! cysteine metabolic process GO:0006534 10 6 0,000 0,01268378 0,06751585 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,01268378 0,06736681 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,01268378 0,06721842 ! glutamate catabolic process GO:0006538 10 6 0,000 0,01268378 0,06707069 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,01268378 0,06692361 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,01268378 0,06677716 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,01268378 0,06663136 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,01268378 0,0664862 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,01268378 0,06634166 ! hyperosmotic response GO:0006972 9 6 0,000 0,01268378 0,06619775 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,01268378 0,06605447 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,01268378 0,0659118 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,01268378 0,06576975 ! urea metabolic process GO:0019627 7 6 0,000 0,01268378 0,06562831 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,01268378 0,06548748 ! neutrophil activation GO:0042119 8 6 0,000 0,01268378 0,06534725 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,01268378 0,06520762 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,01268378 0,06506858 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,01268378 0,06493014 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,01268378 0,06479228 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,01268378 0,06465501 ! neuron apoptosis GO:0051402 9 6 0,000 0,01268378 0,06451832 ! nucleoside salvage GO:0043174 9 6 0,000 0,01268378 0,0643822 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,01268378 0,06424666 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,01268378 0,06411169 ! T cell mediated immunity GO:0002456 16 6 0,000 0,01268378 0,06397728 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,01268378 0,06384344 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 0,01268378 0,06371015 ! carnitine transport GO:0015879 10 6 0,000 0,01268378 0,06357743 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,01268378 0,06344525 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01268378 0,06331362 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,01268378 0,06318253 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,01268378 0,06305199 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,01268378 0,06292199 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,01268378 0,06279252 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,01268378 0,06266358 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,01268378 0,06253517 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,01268378 0,06240729 ! establishment of spindle localization GO:0051293 12 6 0,000 0,01268378 0,06227993 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,01268378 0,06215308 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,01268378 0,06202676 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,01268378 0,06190094 ! neural nucleus development GO:0048857 14 6 0,000 0,01268378 0,06177564 ! response to UV-C GO:0010225 11 6 0,000 0,01268378 0,06165084 ! astrocyte development GO:0014002 15 6 0,000 0,01268378 0,06152654 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,01268378 0,06140274 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,01268378 0,06127945 ! interaction with symbiont GO:0051702 13 6 0,000 0,01268378 0,06115664 ! regulation of dendrite development GO:0050773 16 6 0,000 0,01268378 0,06103433 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,01268378 0,0609125 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,01268378 0,06079116 ! response to copper ion GO:0046688 10 6 0,000 0,01268378 0,06067031 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,01268378 0,06054993 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,01268378 0,06043003 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01268378 0,0603106 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,01268378 0,06019165 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,01268378 0,06007316 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,01268378 0,05995514 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,01268378 0,05983758 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,01268378 0,05972048 ! hair follicle maturation GO:0048820 7 6 0,000 0,01268378 0,05960384 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,01268378 0,05948765 ! Schwann cell development GO:0014044 15 6 0,000 0,01268378 0,05937191 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,01268378 0,05925663 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,01268378 0,05914179 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,01268378 0,0590274 ! subpallium development GO:0021544 10 6 0,000 0,01268378 0,05891344 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,01268378 0,05879993 ! histone ubiquitination GO:0016574 8 6 0,000 0,01268378 0,05868685 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,01268378 0,05857421 ! maintenance of organ identity GO:0048496 9 6 0,000 0,01268378 0,058462 ! G2 phase GO:0051319 16 6 0,000 0,01268378 0,05835022 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,01268378 0,05823886 ! establishment of planar polarity GO:0001736 7 6 0,000 0,01268378 0,05812793 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,01268378 0,05801742 ! membrane to membrane docking GO:0022614 14 6 0,000 0,01268378 0,05790733 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,01268378 0,05779766 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,01268378 0,0576884 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,01268378 0,05757955 ! receptor internalization GO:0031623 10 6 0,000 0,01268378 0,05747112 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,01268378 0,05736309 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,01268378 0,05725547 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01268378 0,05714825 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,01268378 0,05704143 ! protein deubiquitination GO:0016579 14 6 0,000 0,01268378 0,05693501 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 0,01268378 0,05682898 ! protein destabilization GO:0031648 9 6 0,000 0,01268378 0,05672335 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,01268378 0,05661812 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,01268378 0,05651327 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,01268378 0,05640881 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,01268378 0,05630473 ! progesterone metabolic process GO:0042448 10 6 0,000 0,01268378 0,05620104 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,01268378 0,05609773 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,01268378 0,0559948 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,01268378 0,05589224 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,01268378 0,05579006 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,01268378 0,05568826 ! determination of adult lifespan GO:0008340 15 6 0,000 0,01268378 0,05558682 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,01268378 0,05548575 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,01268378 0,05538505 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,01268378 0,05528472 ! catecholamine transport GO:0051937 9 6 0,000 0,01268378 0,05518475 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,01268378 0,05508513 ! sensory cilium assembly GO:0035058 10 6 0,000 0,01268378 0,05498588 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,01268378 0,05488699 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,01268378 0,05478845 ! maternal placenta development GO:0001893 12 6 0,000 0,01268378 0,05469026 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,01268378 0,05459242 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,01268378 0,05449494 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,01268378 0,0543978 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,01268378 0,054301 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,01268378 0,05420455 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,01268378 0,05410845 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,01268378 0,05401268 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 1,000 0,01293027 0,05496505 GO:0045937|positive regulation of phosphate metabolic process, ! intracellular protein transmembrane transport GO:0065002 153 81 1,000 0,01293027 0,05486811 ! regulation of neuron differentiation GO:0045664 167 81 1,000 0,01293027 0,05477151 ! negative regulation of growth GO:0045926 155 84 1,000 0,01385549 0,05858752 ! regulation of transmission of nerve impulse GO:0051969 141 84 1,000 0,01385549 0,05848474 ! positive regulation of cell activation GO:0050867 145 85 1,000 0,01417012 0,05970806 GO:0002696|positive regulation of leukocyte activation, ! mitochondrion organization GO:0007005 148 86 1,000 0,01448784 0,0609401 ! tRNA transcription GO:0009304 14 7 0,000 0,01478229 0,06207012 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,01478229 0,06196199 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,01478229 0,06185423 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,01478229 0,06174684 ! regulation of helicase activity GO:0051095 15 7 0,000 0,01478229 0,06163983 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,01478229 0,06153318 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,01478229 0,06142691 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,01478229 0,061321 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,01478229 0,06121546 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,01478229 0,06111027 ! prostate gland development GO:0030850 13 7 0,000 0,01478229 0,06100545 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,01478229 0,06090099 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,01478229 0,06079689 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,01478229 0,06069314 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,01478229 0,06058974 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01478229 0,0604867 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,01478229 0,06038401 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,01478229 0,06028166 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 0,01478229 0,06017966 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,01478229 0,06007801 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,01478229 0,05997669 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,01478229 0,05987572 ! glycolipid transport GO:0046836 10 7 0,000 0,01478229 0,05977509 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,01478229 0,0596748 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,01478229 0,05957484 ! neuron adhesion GO:0007158 12 7 0,000 0,01478229 0,05947522 ! N-terminal protein amino acid acetylation GO:0006474 13 7 0,000 0,01478229 0,05937593 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,01478229 0,05927697 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,01478229 0,05917834 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,01478229 0,05908003 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,01478229 0,05898206 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,01478229 0,0588844 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,01478229 0,05878707 ! mRNA stabilization GO:0048255 18 7 0,000 0,01478229 0,05869007 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,01478229 0,05859338 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,01478229 0,05849701 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,01478229 0,05840095 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,01478229 0,05830521 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,01478229 0,05820979 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,01478229 0,05811467 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,01478229 0,05801987 ! lipoprotein transport GO:0042953 14 7 0,000 0,01478229 0,05792537 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,01478229 0,05783119 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,01478229 0,0577373 ! rhythmic behavior GO:0007622 15 7 0,000 0,01478229 0,05764373 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,01478229 0,05755045 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,01478229 0,05745748 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,01478229 0,05736481 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,01478229 0,05727243 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,01478229 0,05718035 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,01478229 0,05708857 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,01478229 0,05699708 ! mechanosensory behavior GO:0007638 14 7 0,000 0,01478229 0,05690589 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,01478229 0,05681498 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,01478229 0,05672437 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,01478229 0,05663404 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01478229 0,05654401 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,01478229 0,05645425 ! spinal cord patterning GO:0021511 13 7 0,000 0,01478229 0,05636479 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,01478229 0,0562756 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,01478229 0,0561867 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,01478229 0,05609807 ! adrenal gland development GO:0030325 17 7 0,000 0,01478229 0,05600973 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,01478229 0,05592167 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,01478229 0,05583388 ! ovulation GO:0030728 9 7 0,000 0,01478229 0,05574636 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,01478229 0,05565912 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,01478229 0,05557216 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,01478229 0,05548546 ! microtubule nucleation GO:0007020 20 7 0,000 0,01478229 0,05539903 ! proline biosynthetic process GO:0006561 10 7 0,000 0,01478229 0,05531288 ! thyroid hormone generation GO:0006590 13 7 0,000 0,01478229 0,05522699 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,01478229 0,05514136 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,01478229 0,05505601 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,01478229 0,05497091 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,01478229 0,05488608 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,01478229 0,05480151 ! galactose metabolic process GO:0006012 13 7 0,000 0,01478229 0,0547172 ! vesicle fusion GO:0006906 17 7 0,000 0,01478229 0,05463315 ! response to dietary excess GO:0002021 8 7 0,000 0,01478229 0,05454935 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,01478229 0,05446582 ! intracellular pH reduction GO:0051452 11 7 0,000 0,01478229 0,05438254 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,01478229 0,05429951 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,01478229 0,05421674 ! organ growth GO:0035265 15 7 0,000 0,01478229 0,05413422 ! purine salvage GO:0043101 10 7 0,000 0,01478229 0,05405194 ! nucleoside transport GO:0015858 8 7 0,000 0,01478229 0,05396992 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,01478229 0,05388815 ! parturition GO:0007567 14 7 0,000 0,01478229 0,05380663 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,01478229 0,05372535 ! rRNA modification GO:0000154 14 7 0,000 0,01478229 0,05364431 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,01478229 0,05356352 ! spindle checkpoint GO:0031577 15 7 0,000 0,01478229 0,05348298 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,01478229 0,05340267 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,01478229 0,05332261 ! macrophage differentiation GO:0030225 11 7 0,000 0,01478229 0,05324278 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,01478229 0,0531632 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,01478229 0,05308385 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,01478229 0,05300474 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,01478229 0,05292586 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 0,01478229 0,05284722 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,01478229 0,05276881 ! fibrinolysis GO:0042730 10 7 0,000 0,01478229 0,05269064 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,01478229 0,05261269 ! eating behavior GO:0042755 7 7 0,000 0,01478229 0,05253498 ! B cell lineage commitment GO:0002326 21 7 0,000 0,01478229 0,05245749 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,01478229 0,05238023 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,01478229 0,05230321 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,01478229 0,0522264 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,01478229 0,05214982 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,01478229 0,05207347 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,01478229 0,05199734 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,01478229 0,05192143 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,01478229 0,05184574 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,01478229 0,05177028 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,01478229 0,05169503 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,01478229 0,05162 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,01478229 0,05154519 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,01478229 0,05147059 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,01478229 0,05139621 ! regulation of meiosis GO:0040020 12 7 0,000 0,01478229 0,05132205 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,01478229 0,0512481 ! T cell lineage commitment GO:0002360 16 7 0,000 0,01478229 0,05117436 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,01478229 0,05110083 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,01478229 0,05102752 ! oxygen homeostasis GO:0032364 12 7 0,000 0,01478229 0,05095441 ! transcription termination GO:0006353 13 7 0,000 0,01478229 0,05088152 ! response to tumor cell GO:0002347 13 7 0,000 0,01478229 0,05080883 ! regulation of respiratory burst GO:0060263 11 7 0,000 0,01478229 0,05073635 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,01478229 0,05066407 ! anaphase GO:0051322 17 7 0,000 0,01478229 0,050592 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,01478229 0,05052014 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,01478229 0,05044848 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,01478229 0,05037702 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,01478229 0,05030577 ! diuresis GO:0030146 12 7 0,000 0,01478229 0,05023472 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,01478229 0,05016386 ! thiamin metabolic process GO:0006772 7 7 0,000 0,01478229 0,05009321 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,01478229 0,05002276 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,01478229 0,0499525 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,01478229 0,04988244 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,01478229 0,04981258 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,01478229 0,04974291 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,01478229 0,04967343 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,01478229 0,04960416 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,01478229 0,04953507 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,01478229 0,04946617 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,01478229 0,04939747 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,01478229 0,04932896 ! lymph node development GO:0048535 10 7 0,000 0,01478229 0,04926064 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,01478229 0,0491925 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,01478229 0,04912456 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,01478229 0,0490568 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,01478229 0,04898923 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,01478229 0,04892184 ! adult feeding behavior GO:0008343 9 7 0,000 0,01478229 0,04885464 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,01478229 0,04878763 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,01478229 0,04872079 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,01478229 0,04865414 ! muscle adaptation GO:0043500 14 7 0,000 0,01478229 0,04858768 ! embryonic heart tube development GO:0035050 10 7 0,000 0,01478229 0,04852139 ! retina homeostasis GO:0001895 12 7 0,000 0,01478229 0,04845529 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,01478229 0,04838936 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,01478229 0,04832361 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,01478229 0,04825805 ! protein prenylation GO:0018342 18 7 0,000 0,01478229 0,04819266 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,01478229 0,04812744 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,01478229 0,0480624 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,01478229 0,04799754 ! regulation of protein transport GO:0051223 154 87 1,000 0,01480863 0,04801828 GO:0070201|regulation of establishment of protein localization, ! gland development GO:0048732 206 88 1,000 0,01513248 0,04900236 ! regulation of cell adhesion GO:0030155 212 89 1,000 0,01545938 0,04999365 ! ossification GO:0001503 188 90 1,000 0,01578932 0,05099207 ! bone development GO:0060348 189 91 1,000 0,01612227 0,05199755 ! regulation of membrane potential GO:0042391 164 93 1,000 0,01679716 0,05410171 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,01687641 0,05428427 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,01687641 0,05421179 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,01687641 0,05413951 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,01687641 0,05406742 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,01687641 0,05399552 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,01687641 0,05392381 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,01687641 0,0538523 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,01687641 0,05378097 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,01687641 0,05370983 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,01687641 0,05363888 ! meiotic prophase I GO:0007128 13 8 0,000 0,01687641 0,05356811 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,01687641 0,05349754 ! oligopeptide transport GO:0006857 15 8 0,000 0,01687641 0,05342715 ! UTP metabolic process GO:0046051 8 8 0,000 0,01687641 0,05335694 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,01687641 0,05328692 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,01687641 0,05321708 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,01687641 0,05314742 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,01687641 0,05307795 ! succinate metabolic process GO:0006105 14 8 0,000 0,01687641 0,05300866 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,01687641 0,05293954 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,01687641 0,05287061 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,01687641 0,05280186 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,01687641 0,05273329 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,01687641 0,05266489 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,01687641 0,05259667 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,01687641 0,05252863 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,01687641 0,05246076 ! reflex GO:0060004 16 8 0,000 0,01687641 0,05239307 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,01687641 0,05232555 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,01687641 0,05225821 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,01687641 0,05219104 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,01687641 0,05212404 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,01687641 0,05205722 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,01687641 0,05199056 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,01687641 0,05192408 ! pigment granule organization GO:0048753 16 8 0,000 0,01687641 0,05185777 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,01687641 0,05179162 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,01687641 0,05172564 ! astrocyte differentiation GO:0048708 18 8 0,000 0,01687641 0,05165984 ! histidine metabolic process GO:0006547 16 8 0,000 0,01687641 0,05159419 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,01687641 0,05152872 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,01687641 0,05146341 ! glycine catabolic process GO:0006546 13 8 0,000 0,01687641 0,05139827 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,01687641 0,05133329 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,01687641 0,05126847 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 12 8 0,000 0,01687641 0,05120382 ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,01687641 0,05113933 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,01687641 0,05107501 ! melanin metabolic process GO:0006582 15 8 0,000 0,01687641 0,05101084 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,01687641 0,05094684 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,01687641 0,050883 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,01687641 0,05081931 ! macrophage activation GO:0042116 12 8 0,000 0,01687641 0,05075579 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,01687641 0,05069242 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,01687641 0,05062922 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,01687641 0,05056617 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,01687641 0,05050327 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,01687641 0,05044053 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,01687641 0,05037795 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,01687641 0,05031553 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,01687641 0,05025326 ! osteoblast development GO:0002076 16 8 0,000 0,01687641 0,05019114 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,01687641 0,05012917 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,01687641 0,05006736 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,01687641 0,0500057 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,01687641 0,0499442 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,01687641 0,04988284 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,01687641 0,04982163 ! response to UV-B GO:0010224 16 8 0,000 0,01687641 0,04976058 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,01687641 0,04969967 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,01687641 0,04963891 ! intermediate filament organization GO:0045109 12 8 0,000 0,01687641 0,0495783 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,01687641 0,04951784 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,01687641 0,04945753 ! cellular extravasation GO:0045123 12 8 0,000 0,01687641 0,04939736 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,01687641 0,04933734 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,01687641 0,04927746 ! response to antibiotic GO:0046677 11 8 0,000 0,01687641 0,04921773 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,01687641 0,04915815 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,01687641 0,04909871 ! DNA topological change GO:0006265 12 8 0,000 0,01687641 0,04903941 ! response to tropane GO:0014073 15 8 0,000 0,01687641 0,04898025 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,01687641 0,04892124 ! melanosome transport GO:0032402 13 8 0,000 0,01687641 0,04886237 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,01687641 0,04880364 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,01687641 0,04874505 ! mast cell activation GO:0045576 14 8 0,000 0,01687641 0,04868661 ! multicellular organismal aging GO:0010259 18 8 0,000 0,01687641 0,0486283 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,01687641 0,04857013 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,01687641 0,0485121 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,01687641 0,04845421 ! nucleosome disassembly GO:0006337 14 8 0,000 0,01687641 0,04839646 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,01687641 0,04833885 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,01687641 0,04828137 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,01687641 0,04822403 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,01687641 0,04816682 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,01687641 0,04810975 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,01687641 0,04805282 ! intracellular lipid transport GO:0032365 13 8 0,000 0,01687641 0,04799602 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,01687641 0,04793935 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,01687641 0,04788282 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,01687641 0,04782642 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,01687641 0,04777015 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,01687641 0,04771402 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,01687641 0,04765802 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,01687641 0,04760215 ! hormone catabolic process GO:0042447 17 8 0,000 0,01687641 0,04754641 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,01687641 0,0474908 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,01687641 0,04743532 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,01687641 0,04737997 ! ATP catabolic process GO:0006200 11 8 0,000 0,01687641 0,04732474 ! blastocyst growth GO:0001832 19 8 0,000 0,01687641 0,04726965 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,01687641 0,04721469 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,01687641 0,04715985 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,01687641 0,04710514 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,01687641 0,04705056 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,01687641 0,0469961 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,01687641 0,04694177 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,01687641 0,04688756 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,01687641 0,04683348 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,01687641 0,04677953 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,01687641 0,0467257 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,01687641 0,04667199 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,01687641 0,0466184 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,01687641 0,04656494 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,01687641 0,0465116 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,01687641 0,04645839 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,01687641 0,04640529 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,01687641 0,04635232 ! regulation of T cell activation GO:0050863 158 94 1,000 0,01713909 0,04702012 ! forebrain development GO:0030900 188 95 1,000 0,01748397 0,04791166 ! regulation of protein localization GO:0032880 176 97 1,000 0,01818257 0,04976936 ! response to virus GO:0009615 160 98 1,000 0,01853626 0,05067983 ! skeletal muscle tissue development GO:0007519 186 99 1,000 0,01889286 0,05159617 GO:0060538|skeletal muscle organ development, ! regulation of developmental growth GO:0048638 15 9 0,000 0,01896614 0,05173757 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,01896614 0,05167898 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,01896614 0,05162052 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,01896614 0,05156219 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,01896614 0,05150399 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,01896614 0,05144593 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,01896614 0,05138799 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,01896614 0,05133019 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,01896614 0,05127252 ! phosphate transport GO:0006817 19 9 0,000 0,01896614 0,05121497 ! reproductive behavior GO:0019098 19 9 0,000 0,01896614 0,05115756 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,01896614 0,05110027 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,01896614 0,05104311 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,01896614 0,05098608 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,01896614 0,05092917 ! GTP metabolic process GO:0046039 9 9 0,000 0,01896614 0,0508724 ! RNA methylation GO:0001510 15 9 0,000 0,01896614 0,05081575 ! elastic fiber assembly GO:0048251 15 9 0,000 0,01896614 0,05075922 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,01896614 0,05070282 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,01896614 0,05064655 ! artery development GO:0060840 24 9 0,000 0,01896614 0,0505904 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,01896614 0,05053437 ! regulation of glycolysis GO:0006110 21 9 0,000 0,01896614 0,05047847 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,01896614 0,0504227 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,01896614 0,05036704 ! chemosensory behavior GO:0007635 20 9 0,000 0,01896614 0,05031151 ! microtubule bundle formation GO:0001578 21 9 0,000 0,01896614 0,0502561 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,01896614 0,05020081 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,01896614 0,05014565 ! leukocyte degranulation GO:0043299 16 9 0,000 0,01896614 0,0500906 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,01896614 0,05003568 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,01896614 0,04998088 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,01896614 0,04992619 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,01896614 0,04987163 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,01896614 0,04981718 ! protein targeting to ER GO:0045047 22 9 0,000 0,01896614 0,04976286 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,01896614 0,04970865 ! T cell selection GO:0045058 23 9 0,000 0,01896614 0,04965456 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 0,000 0,01896614 0,04960059 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,01896614 0,04954673 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,01896614 0,04949299 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,01896614 0,04943937 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,01896614 0,04938587 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,01896614 0,04933247 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,01896614 0,0492792 ! mannose metabolic process GO:0006013 13 9 0,000 0,01896614 0,04922604 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,01896614 0,04917299 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,01896614 0,04912006 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,01896614 0,04906725 ! receptor clustering GO:0043113 18 9 0,000 0,01896614 0,04901454 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,01896614 0,04896195 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,01896614 0,04890947 ! ruffle organization GO:0031529 15 9 0,000 0,01896614 0,04885711 ! retinol metabolic process GO:0042572 18 9 0,000 0,01896614 0,04880485 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,01896614 0,04875271 ! behavioral fear response GO:0001662 22 9 0,000 0,01896614 0,04870068 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,01896614 0,04864876 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,01896614 0,04859695 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,01896614 0,04854525 GO:0030204|chondroitin sulfate metabolic process, ! protein heterooligomerization GO:0051291 16 9 0,000 0,01896614 0,04849367 ! oligodendrocyte development GO:0014003 10 9 0,000 0,01896614 0,04844219 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,01896614 0,04839082 ! segment specification GO:0007379 13 9 0,000 0,01896614 0,04833955 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,01896614 0,0482884 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,01896614 0,04823736 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,01896614 0,04818642 ! response to amine stimulus GO:0014075 13 9 0,000 0,01896614 0,04813559 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,01896614 0,04808487 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,01896614 0,04803425 ! erythrocyte development GO:0048821 15 9 0,000 0,01896614 0,04798374 ! gas homeostasis GO:0033483 16 9 0,000 0,01896614 0,04793334 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,01896614 0,04788304 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,01896614 0,04783285 ! renal water homeostasis GO:0003091 14 9 0,000 0,01896614 0,04778276 ! postreplication repair GO:0006301 22 9 0,000 0,01896614 0,04773278 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,01896614 0,0476829 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,01896614 0,04763313 ! icosanoid secretion GO:0032309 15 9 0,000 0,01896614 0,04758346 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,01896614 0,0475339 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,01896614 0,04748443 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,01896614 0,04743507 ! regulation of cell division GO:0051302 15 9 0,000 0,01896614 0,04738581 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,01896614 0,04733666 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,01896614 0,04728761 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,01896614 0,04723865 ! sterol catabolic process GO:0016127 11 9 0,000 0,01896614 0,0471898 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,01896614 0,04714105 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,01896614 0,0470924 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,01896614 0,04704385 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,01896614 0,04699541 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,01896614 0,04694706 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,01896614 0,04689881 ! musculoskeletal movement GO:0050881 14 9 0,000 0,01896614 0,04685066 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,01896614 0,0468026 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,01896614 0,04675465 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,01896614 0,0467068 ! purine base metabolic process GO:0006144 21 9 0,000 0,01896614 0,04665904 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,01896614 0,04661138 ! pigment granule transport GO:0051904 17 9 0,000 0,01896614 0,04656382 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,01896614 0,04651635 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,01896614 0,04646898 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,01896614 0,04642171 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,01896614 0,04637453 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,01896614 0,04632745 ! mitochondrion localization GO:0051646 15 9 0,000 0,01896614 0,04628047 ! cell cycle arrest GO:0007050 213 100 1,000 0,01925236 0,04693128 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,02105151 0,05126511 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,02105151 0,05121327 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,02105151 0,05116154 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,02105151 0,05110992 ! synapsis GO:0007129 13 10 0,000 0,02105151 0,05105839 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,02105151 0,05100698 ! N-glycan processing GO:0006491 20 10 0,000 0,02105151 0,05095566 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,02105151 0,05090445 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,02105151 0,05085334 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,02105151 0,05080233 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,02105151 0,05075143 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,02105151 0,05070063 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,02105151 0,05064993 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,02105151 0,05059933 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,02105151 0,05054883 ! androgen metabolic process GO:0008209 17 10 0,000 0,02105151 0,05049843 ! phospholipid efflux GO:0033700 16 10 0,000 0,02105151 0,05044813 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,02105151 0,05039794 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,02105151 0,05034784 ! lung alveolus development GO:0048286 26 10 0,000 0,02105151 0,05029784 ! pathogenesis GO:0009405 13 10 0,000 0,02105151 0,05024794 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,02105151 0,05019814 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,02105151 0,05014844 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,02105151 0,05009884 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,02105151 0,05004934 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,02105151 0,04999993 ! endoderm development GO:0007492 16 10 0,000 0,02105151 0,04995062 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,02105151 0,04990141 ! arginine catabolic process GO:0006527 13 10 0,000 0,02105151 0,04985229 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,02105151 0,04980327 ! proline metabolic process GO:0006560 13 10 0,000 0,02105151 0,04975435 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,02105151 0,04970552 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,02105151 0,04965679 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,02105151 0,04960816 ! V(D)J recombination GO:0033151 28 10 0,000 0,02105151 0,04955962 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,02105151 0,04951117 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,02105151 0,04946282 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,02105151 0,04941456 ! B cell proliferation GO:0042100 18 10 0,000 0,02105151 0,0493664 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,02105151 0,04931833 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,02105151 0,04927036 ! multicellular organism growth GO:0035264 18 10 0,000 0,02105151 0,04922248 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,02105151 0,04917469 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,02105151 0,04912699 ! epithelial cell development GO:0002064 20 10 0,000 0,02105151 0,04907939 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,02105151 0,04903188 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,02105151 0,04898446 ! macroautophagy GO:0016236 17 10 0,000 0,02105151 0,04893713 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,02105151 0,04888989 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,02105151 0,04884275 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,02105151 0,04879569 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,02105151 0,04874873 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 0,02105151 0,04870185 ! copper ion homeostasis GO:0055070 13 10 0,000 0,02105151 0,04865507 ! regulation of bone resorption GO:0045124 25 10 0,000 0,02105151 0,04860838 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,02105151 0,04856177 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,02105151 0,04851526 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,02105151 0,04846883 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,02105151 0,04842249 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,02105151 0,04837624 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,02105151 0,04833008 ! blastoderm segmentation GO:0007350 18 10 0,000 0,02105151 0,04828401 ! response to dsRNA GO:0043331 20 10 0,000 0,02105151 0,04823803 ! DNA ligation GO:0006266 19 10 0,000 0,02105151 0,04819213 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,02105151 0,04814632 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,02105151 0,0481006 ! melanosome localization GO:0032400 16 10 0,000 0,02105151 0,04805496 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,02105151 0,04800941 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,02105151 0,04796395 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,02105151 0,04791857 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,02105151 0,04787328 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,02105151 0,04782807 ! mRNA cleavage GO:0006379 17 10 0,000 0,02105151 0,04778295 ! protein sumoylation GO:0016925 15 10 0,000 0,02105151 0,04773791 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,02105151 0,04769296 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,02105151 0,0476481 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,02105151 0,04760332 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,02105151 0,04755862 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,02105151 0,047514 ! salivary gland development GO:0007431 27 10 0,000 0,02105151 0,04746947 ! prophase GO:0051324 15 10 0,000 0,02105151 0,04742503 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,02105151 0,04738066 ! apical protein localization GO:0045176 15 10 0,000 0,02105151 0,04733638 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,02105151 0,04729218 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,02105151 0,04724807 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,02105151 0,04720403 ! midbrain development GO:0030901 13 10 0,000 0,02105151 0,04716008 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,02105151 0,04711621 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,02105151 0,04707242 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,02105151 0,04702872 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,02105151 0,04698509 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,02105151 0,04694155 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,02105151 0,04689808 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,02105151 0,0468547 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 0,02105151 0,04681139 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 0,02105151 0,04676817 ! oocyte development GO:0048599 17 10 0,000 0,02105151 0,04672503 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,02105151 0,04668196 ! blastocyst formation GO:0001825 17 10 0,000 0,02105151 0,04663898 ! cerebellar cortex development GO:0021695 15 10 0,000 0,02105151 0,04659607 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,02105151 0,04655324 ! activation of innate immune response GO:0002218 12 10 0,000 0,02105151 0,04651049 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,02105151 0,04646782 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,02105151 0,04642523 ! response to nicotine GO:0035094 20 10 0,000 0,02105151 0,04638272 ! establishment of cell polarity GO:0030010 16 10 0,000 0,02105151 0,04634028 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,02105151 0,04629792 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,02105151 0,04625564 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,02313251 0,05078177 ! respiratory burst GO:0045730 17 11 0,000 0,02313251 0,05073548 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,02313251 0,05068927 ! neuron fate specification GO:0048665 17 11 0,000 0,02313251 0,05064314 ! telencephalon cell migration GO:0022029 20 11 0,000 0,02313251 0,05059711 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,02313251 0,05055115 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,02313251 0,05050528 ! thyroid gland development GO:0030878 26 11 0,000 0,02313251 0,05045949 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,02313251 0,05041378 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,02313251 0,05036816 ! response to pain GO:0048265 24 11 0,000 0,02313251 0,05032262 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,02313251 0,05027716 ! T cell proliferation GO:0042098 26 11 0,000 0,02313251 0,05023178 ! blood vessel remodeling GO:0001974 29 11 0,000 0,02313251 0,05018649 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,02313251 0,05014128 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,02313251 0,05009614 ! bone resorption GO:0045453 16 11 0,000 0,02313251 0,05005109 ! peptide or protein amino-terminal blocking GO:0018409 21 11 0,000 0,02313251 0,05000612 ! ventral spinal cord development GO:0021517 21 11 0,000 0,02313251 0,04996124 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,02313251 0,04991643 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,02313251 0,0498717 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,02313251 0,04982705 ! melanocyte differentiation GO:0030318 21 11 0,000 0,02313251 0,04978248 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,02313251 0,04973799 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,02313251 0,04969359 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,02313251 0,04964926 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,02313251 0,04960501 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,02313251 0,04956083 ! lipid digestion GO:0044241 18 11 0,000 0,02313251 0,04951674 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,02313251 0,04947273 ! UV protection GO:0009650 19 11 0,000 0,02313251 0,04942879 ! adult heart development GO:0007512 14 11 0,000 0,02313251 0,04938493 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,02313251 0,04934115 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,02313251 0,04929745 ! temperature homeostasis GO:0001659 17 11 0,000 0,02313251 0,04925382 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,02313251 0,04921027 ! negative regulation of ossification GO:0030279 26 11 0,000 0,02313251 0,0491668 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,02313251 0,0491234 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,02313251 0,04908008 ! regulation of organ growth GO:0046620 13 11 0,000 0,02313251 0,04903684 ! pigment granule localization GO:0051875 20 11 0,000 0,02313251 0,04899368 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,02313251 0,04895059 ! vasoconstriction GO:0042310 18 11 0,000 0,02313251 0,04890757 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,02313251 0,04886463 ! embryonic axis specification GO:0000578 18 11 0,000 0,02313251 0,04882177 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,02313251 0,04877898 ! snRNA metabolic process GO:0016073 24 11 0,000 0,02313251 0,04873627 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,02313251 0,04869363 ! DNA methylation GO:0006306 19 11 0,000 0,02313251 0,04865106 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,02313251 0,04860857 ! zymogen activation GO:0031638 15 11 0,000 0,02313251 0,04856616 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,02313251 0,04852382 ! neuroblast proliferation GO:0007405 24 11 0,000 0,02313251 0,04848155 ! nucleosome positioning GO:0016584 15 11 0,000 0,02313251 0,04843935 ! regulation of isotype switching GO:0045191 22 11 0,000 0,02313251 0,04839723 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,02313251 0,04835518 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,02313251 0,04831321 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,02313251 0,04827131 ! acid secretion GO:0046717 18 11 0,000 0,02313251 0,04822948 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,02313251 0,04818772 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,02313251 0,04814603 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,02313251 0,04810442 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,02313251 0,04806288 ! oocyte differentiation GO:0009994 18 11 0,000 0,02313251 0,04802141 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,02313251 0,04798001 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,02313251 0,04793869 ! cholesterol efflux GO:0033344 19 11 0,000 0,02313251 0,04789743 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,02313251 0,04785625 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,02313251 0,04781513 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,02313251 0,04777409 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,02313251 0,04773312 ! embryonic gut development GO:0048566 15 11 0,000 0,02313251 0,04769222 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,02313251 0,04765138 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,02313251 0,04761062 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,02313251 0,04756993 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,02313251 0,04752931 ! defense response to fungus GO:0050832 13 11 0,000 0,02313251 0,04748875 ! developmental induction GO:0031128 19 11 0,000 0,02313251 0,04744827 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,02313251 0,04740785 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,02313251 0,0473675 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,02313251 0,04732722 ! sequestering of metal ion GO:0051238 14 11 0,000 0,02313251 0,04728701 ! lamellipodium assembly GO:0030032 20 11 0,000 0,02313251 0,04724687 ! regulation of embryonic development GO:0045995 27 11 0,000 0,02313251 0,0472068 ! nucleus localization GO:0051647 19 11 0,000 0,02313251 0,04716679 ! regulation of synapse organization GO:0050807 17 11 0,000 0,02313251 0,04712686 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,02520916 0,05131407 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,02520916 0,05127069 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,02520916 0,05122739 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 0,02520916 0,05118416 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,02520916 0,051141 ! virus-host interaction GO:0019048 29 12 0,000 0,02520916 0,05109792 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,02520916 0,05105491 ! cartilage condensation GO:0001502 20 12 0,000 0,02520916 0,05101197 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,02520916 0,0509691 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,02520916 0,0509263 ! protein complex disassembly GO:0043241 27 12 0,000 0,02520916 0,05088358 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,02520916 0,05084093 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,02520916 0,05079835 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,02520916 0,05075584 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,02520916 0,0507134 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,02520916 0,05067103 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,02520916 0,05062874 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,02520916 0,05058651 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,02520916 0,05054436 ! drug transport GO:0015893 16 12 0,000 0,02520916 0,05050227 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,02520916 0,05046026 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,02520916 0,05041831 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,02520916 0,05037643 ! polyamine metabolic process GO:0006595 17 12 0,000 0,02520916 0,05033463 ! focal adhesion formation GO:0048041 35 12 0,000 0,02520916 0,05029289 ! mitotic spindle organization GO:0007052 21 12 0,000 0,02520916 0,05025122 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,02520916 0,05020963 ! forebrain cell migration GO:0021885 21 12 0,000 0,02520916 0,0501681 ! asymmetric protein localization GO:0008105 20 12 0,000 0,02520916 0,05012663 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,02520916 0,05008524 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,02520916 0,05004392 ! entry into host cell GO:0030260 32 12 0,000 0,02520916 0,05000266 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,02520916 0,04996147 ! monoamine transport GO:0015844 18 12 0,000 0,02520916 0,04992035 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,02520916 0,0498793 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,02520916 0,04983831 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,02520916 0,0497974 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,02520916 0,04975654 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,02520916 0,04971576 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,02520916 0,04967504 ! protein homotetramerization GO:0051289 21 12 0,000 0,02520916 0,04963439 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,02520916 0,04959381 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,02520916 0,04955329 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,02520916 0,04951284 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,02520916 0,04947245 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,02520916 0,04943213 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,02520916 0,04939188 ! cranial nerve development GO:0021545 20 12 0,000 0,02520916 0,04935169 ! fucose catabolic process GO:0019317 22 12 0,000 0,02520916 0,04931157 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,02520916 0,04927151 ! histone acetylation GO:0016573 26 12 0,000 0,02520916 0,04923152 ! histone methylation GO:0016571 26 12 0,000 0,02520916 0,04919159 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,02520916 0,04915172 ! autonomic nervous system development GO:0048483 24 12 0,000 0,02520916 0,04911193 ! gland morphogenesis GO:0022612 29 12 0,000 0,02520916 0,04907219 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,02520916 0,04903252 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,02520916 0,04899291 ! T cell homeostasis GO:0043029 25 12 0,000 0,02520916 0,04895337 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,02520916 0,04891389 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,02520916 0,04887448 ! spleen development GO:0048536 22 12 0,000 0,02520916 0,04883513 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,02520916 0,04879584 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,02520916 0,04875661 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,02520916 0,04871745 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,02520916 0,04867835 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,02520916 0,04863932 ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,02520916 0,04860034 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,02520916 0,04856143 ! response to cold GO:0009409 17 12 0,000 0,02520916 0,04852258 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,02520916 0,0484838 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,02520916 0,04844507 ! cGMP metabolic process GO:0046068 18 13 0,000 0,02728146 0,05238562 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,02728146 0,05234385 ! regulation of chemokine production GO:0032642 18 13 0,000 0,02728146 0,05230214 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,02728146 0,0522605 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,02728146 0,05221892 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,02728146 0,05217741 ! lipid localization GO:0010876 28 13 0,000 0,02728146 0,05213597 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,02728146 0,05209459 ! organelle fusion GO:0048284 32 13 0,000 0,02728146 0,05205328 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,02728146 0,05201203 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,02728146 0,05197085 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,02728146 0,05192973 ! endocrine pancreas development GO:0031018 22 13 0,000 0,02728146 0,05188868 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,02728146 0,0518477 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,02728146 0,05180677 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,02728146 0,05176592 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,02728146 0,05172512 ! methionine metabolic process GO:0006555 27 13 0,000 0,02728146 0,0516844 ! plasma membrane organization GO:0007009 24 13 0,000 0,02728146 0,05164373 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,02728146 0,05160313 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,02728146 0,05156259 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,02728146 0,05152212 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,02728146 0,05148171 ! response to X-ray GO:0010165 25 13 0,000 0,02728146 0,05144137 ! cytokine metabolic process GO:0042107 22 13 0,000 0,02728146 0,05140108 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,02728146 0,05136086 ! exocrine system development GO:0035272 32 13 0,000 0,02728146 0,05132071 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 0,02728146 0,05128061 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,02728146 0,05124058 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,02728146 0,05120061 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,02728146 0,0511607 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,02728146 0,05112086 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,02728146 0,05108108 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,02728146 0,05104136 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,02728146 0,0510017 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,02728146 0,0509621 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,02728146 0,05092256 ! regulation of cellular pH GO:0030641 22 13 0,000 0,02728146 0,05088309 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,02728146 0,05084367 ! ribosome assembly GO:0042255 17 13 0,000 0,02728146 0,05080432 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,02728146 0,05076503 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,02728146 0,0507258 ! chromatin silencing GO:0006342 26 13 0,000 0,02728146 0,05068663 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,02728146 0,05064752 ! regulation of epidermis development GO:0045682 19 13 0,000 0,02728146 0,05060847 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,02728146 0,05056948 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,02728146 0,05053055 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,02728146 0,05049168 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,02728146 0,05045287 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,02728146 0,05041412 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,02728146 0,05037543 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,02728146 0,0503368 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,02728146 0,05029822 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,02728146 0,05025971 ! embryonic placenta development GO:0001892 23 13 0,000 0,02728146 0,05022126 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,02728146 0,05018286 ! insulin secretion GO:0030073 23 13 0,000 0,02728146 0,05014453 ! actin filament polymerization GO:0030041 24 13 0,000 0,02728146 0,05010625 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,02728146 0,05006803 ! acrosome reaction GO:0007340 18 13 0,000 0,02728146 0,05002987 ! rRNA transcription GO:0009303 25 14 0,000 0,02934942 0,05378119 ! lactation GO:0007595 26 14 0,000 0,02934942 0,05374026 ! N-terminal protein amino acid modification GO:0031365 27 14 0,000 0,02934942 0,0536994 ! reproductive cellular process GO:0048610 20 14 0,000 0,02934942 0,05365859 ! tRNA modification GO:0006400 20 14 0,000 0,02934942 0,05361785 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,02934942 0,05357717 ! regulation of S phase GO:0033261 23 14 0,000 0,02934942 0,05353655 ! water transport GO:0006833 21 14 0,000 0,02934942 0,05349599 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,02934942 0,05345549 ! non-recombinational repair GO:0000726 25 14 0,000 0,02934942 0,05341506 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,02934942 0,05337468 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,02934942 0,05333437 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,02934942 0,05329412 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,02934942 0,05325393 ! RNA polyadenylation GO:0043631 30 14 0,000 0,02934942 0,05321379 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,02934942 0,05317372 ! palate development GO:0060021 31 14 0,000 0,02934942 0,05313371 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,02934942 0,05309376 ! regulated secretory pathway GO:0045055 23 14 0,000 0,02934942 0,05305387 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,02934942 0,05301404 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,02934942 0,05297427 ! arginine metabolic process GO:0006525 17 14 0,000 0,02934942 0,05293456 ! regulation of heart rate GO:0002027 24 14 0,000 0,02934942 0,05289491 ! organic alcohol transport GO:0015850 29 14 0,000 0,02934942 0,05285532 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,02934942 0,05281579 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,02934942 0,05277631 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,02934942 0,0527369 ! neutral amino acid transport GO:0015804 26 14 0,000 0,02934942 0,05269754 ! L-amino acid transport GO:0015807 30 14 0,000 0,02934942 0,05265824 ! bone mineralization GO:0030282 17 14 0,000 0,02934942 0,052619 ! stem cell development GO:0048864 43 14 0,000 0,02934942 0,05257982 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,02934942 0,0525407 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,02934942 0,05250164 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,02934942 0,05246263 ! cerebellum development GO:0021549 21 14 0,000 0,02934942 0,05242369 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,02934942 0,0523848 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,02934942 0,05234596 ! response to gamma radiation GO:0010332 28 14 0,000 0,02934942 0,05230719 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,02934942 0,05226847 ! cofactor transport GO:0051181 26 14 0,000 0,02934942 0,05222981 ! NADP metabolic process GO:0006739 24 14 0,000 0,02934942 0,05219121 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,02934942 0,05215266 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,02934942 0,05211417 ! intestinal absorption GO:0050892 25 14 0,000 0,02934942 0,05207574 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,02934942 0,05203737 ! oxygen transport GO:0015671 21 14 0,000 0,02934942 0,05199905 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,02934942 0,05196078 ! male genitalia development GO:0030539 24 14 0,000 0,02934942 0,05192258 ! regulation of RNA stability GO:0043487 32 14 0,000 0,02934942 0,05188443 ! regulation of axon extension GO:0030516 37 14 0,000 0,02934942 0,05184633 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,02934942 0,05180829 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,03141306 0,05541042 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,03141306 0,05536983 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! superoxide anion generation GO:0042554 20 15 0,000 0,03141306 0,05532929 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,03141306 0,05528882 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,03141306 0,0552484 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,03141306 0,05520804 ! copper ion transport GO:0006825 20 15 0,000 0,03141306 0,05516775 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,03141306 0,05512751 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,03141306 0,05508733 ! sulfate transport GO:0008272 23 15 0,000 0,03141306 0,05504721 ! response to cAMP GO:0051591 22 15 0,000 0,03141306 0,05500714 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,03141306 0,05496714 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,03141306 0,05492719 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,03141306 0,0548873 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,03141306 0,05484747 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,03141306 0,0548077 ! response to hexose stimulus GO:0009746 22 15 0,000 0,03141306 0,05476798 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,03141306 0,05472832 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,03141306 0,05468872 ! pituitary gland development GO:0021983 29 15 0,000 0,03141306 0,05464918 ! vesicle coating GO:0006901 33 15 0,000 0,03141306 0,05460969 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,03141306 0,05457026 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,03141306 0,05453089 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,03141306 0,05449157 ! regulation of exocytosis GO:0017157 22 15 0,000 0,03141306 0,05445231 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,03141306 0,05441311 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,03141306 0,05437397 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,03141306 0,05433488 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,03141306 0,05429584 ! regulation of vasodilation GO:0042312 26 15 0,000 0,03141306 0,05425687 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,03141306 0,05421794 ! mRNA splice site selection GO:0006376 38 15 0,000 0,03141306 0,05417908 ! tissue regeneration GO:0042246 26 15 0,000 0,03141306 0,05414027 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,03141306 0,05410151 ! water homeostasis GO:0030104 27 15 0,000 0,03141306 0,05406281 ! muscle maintenance GO:0046716 26 15 0,000 0,03141306 0,05402417 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,03141306 0,05398558 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,03141306 0,05394705 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,03141306 0,05390857 ! dopamine metabolic process GO:0042417 35 15 0,000 0,03141306 0,05387014 ! heme biosynthetic process GO:0006783 29 15 0,000 0,03141306 0,05383178 ! cell killing GO:0001906 29 15 0,000 0,03141306 0,05379346 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,03141306 0,0537552 ! detection of bacterium GO:0016045 18 15 0,000 0,03141306 0,053717 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,03141306 0,05367884 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,03141306 0,05364075 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,03141306 0,0536027 ! peptide hormone processing GO:0016486 23 15 0,000 0,03141306 0,05356472 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,03347237 0,05703579 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,03347237 0,05699542 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,03347237 0,05695511 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,03347237 0,05691486 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,03347237 0,05687467 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,03347237 0,05683453 ! bone remodeling GO:0046849 27 16 0,000 0,03347237 0,05679445 ! filopodium assembly GO:0046847 32 16 0,000 0,03347237 0,05675443 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,03347237 0,05671446 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,03347237 0,05667455 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,03347237 0,05663469 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,03347237 0,05659489 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,03347237 0,05655515 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,03347237 0,05651546 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,03347237 0,05647583 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,03347237 0,05643625 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,03347237 0,05639673 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,03347237 0,05635726 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,03347237 0,05631785 ! protein polyubiquitination GO:0000209 34 16 0,000 0,03347237 0,0562785 ! glutamate metabolic process GO:0006536 22 16 0,000 0,03347237 0,0562392 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,03347237 0,05619995 ! response to osmotic stress GO:0006970 25 16 0,000 0,03347237 0,05616076 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,03347237 0,05612162 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,03347237 0,05608254 ! fructose metabolic process GO:0006000 25 16 0,000 0,03347237 0,05604351 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,03347237 0,05600454 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 32 16 0,000 0,03347237 0,05596562 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,03347237 0,05592676 ! negative regulation of immune response GO:0050777 35 16 0,000 0,03347237 0,05588795 ! axon cargo transport GO:0008088 43 16 0,000 0,03347237 0,05584919 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,03347237 0,05581049 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,03347237 0,05577184 ! DNA replication initiation GO:0006270 27 16 0,000 0,03347237 0,05573324 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,03347237 0,0556947 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,03347237 0,05565621 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,03347237 0,05561777 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,03347237 0,05557939 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,03347237 0,05554106 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,03347237 0,05550278 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,03347237 0,05546455 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,03347237 0,05542638 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,03347237 0,05538826 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,03347237 0,05535019 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,03347237 0,05531218 ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,03347237 0,05527421 ! defense response to virus GO:0051607 37 16 0,000 0,03347237 0,0552363 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,03552738 0,0585873 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,03552738 0,05854718 ! metencephalon development GO:0022037 30 17 0,000 0,03552738 0,0585071 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,03552738 0,05846708 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,03552738 0,05842712 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,03552738 0,05838721 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,03552738 0,05834736 ! signal complex assembly GO:0007172 41 17 0,000 0,03552738 0,05830756 ! endothelial cell migration GO:0043542 28 17 0,000 0,03552738 0,05826781 ! inositol metabolic process GO:0006020 28 17 0,000 0,03552738 0,05822812 ! gene silencing by RNA GO:0031047 36 17 0,000 0,03552738 0,05818848 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,03552738 0,0581489 ! glial cell development GO:0021782 27 17 0,000 0,03552738 0,05810937 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,03552738 0,05806989 ! adult walking behavior GO:0007628 33 17 0,000 0,03552738 0,05803047 ! heart looping GO:0001947 30 17 0,000 0,03552738 0,0579911 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,03552738 0,05795178 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,03552738 0,05791252 ! myoblast differentiation GO:0045445 45 17 0,000 0,03552738 0,05787331 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,03552738 0,05783415 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,03552738 0,05779505 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,03552738 0,057756 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,03552738 0,057717 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,03552738 0,05767805 ! glycine metabolic process GO:0006544 28 17 0,000 0,03552738 0,05763916 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,03552738 0,05760032 ! NAD metabolic process GO:0019674 29 17 0,000 0,03552738 0,05756153 ! membrane budding GO:0006900 37 17 0,000 0,03552738 0,0575228 ! DNA integration GO:0015074 29 17 0,000 0,03552738 0,05748411 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,03552738 0,05744548 ! regulation of protein binding GO:0043393 33 17 0,000 0,03552738 0,0574069 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,03552738 0,05736837 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,03552738 0,0573299 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,03552738 0,05729147 ! genitalia development GO:0048806 30 17 0,000 0,03552738 0,0572531 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,03552738 0,05721478 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,03552738 0,05717651 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,03552738 0,05713829 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,03552738 0,05710012 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,03552738 0,057062 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,03552738 0,05702393 ! steroid catabolic process GO:0006706 31 17 0,000 0,03552738 0,05698592 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,03552738 0,05694795 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,03552738 0,05691004 ! gas transport GO:0015669 25 17 0,000 0,03552738 0,05687217 ! organic cation transport GO:0015695 31 17 0,000 0,03552738 0,05683436 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,03552738 0,0567966 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,03552738 0,05675888 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,03552738 0,05672122 ! microspike assembly GO:0030035 36 17 0,000 0,03552738 0,05668361 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,03552738 0,05664604 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,03552738 0,05660853 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,03757809 0,05983645 ! neuron maturation GO:0042551 42 18 0,000 0,03757809 0,05979688 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,03757809 0,05975735 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,03757809 0,05971788 ! phosphoinositide phosphorylation GO:0046854 33 18 0,000 0,03757809 0,05967847 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,03757809 0,0596391 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,03757809 0,05959979 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,03757809 0,05956052 ! memory GO:0007613 31 18 0,000 0,03757809 0,05952131 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,03757809 0,05948215 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,03757809 0,05944305 ! patterning of blood vessels GO:0001569 39 18 0,000 0,03757809 0,05940399 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,03757809 0,05936499 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,03757809 0,05932603 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,03757809 0,05928713 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,03757809 0,05924828 ! glutamine metabolic process GO:0006541 29 18 0,000 0,03757809 0,05920948 ! response to retinoic acid GO:0032526 26 18 0,000 0,03757809 0,05917073 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,03757809 0,05913203 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,03757809 0,05909338 ! response to fungus GO:0009620 21 18 0,000 0,03757809 0,05905478 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,03757809 0,05901624 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,03757809 0,05897774 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,03757809 0,05893929 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,03757809 0,0589009 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,03757809 0,05886255 ! vitamin transport GO:0051180 27 18 0,000 0,03757809 0,05882425 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,03757809 0,058786 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,03757809 0,05874781 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,03757809 0,05870966 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,03757809 0,05867156 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,03757809 0,05863351 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,03757809 0,05859551 ! nerve development GO:0021675 28 18 0,000 0,03757809 0,05855756 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,03757809 0,05851966 ! protein secretion GO:0009306 39 19 0,000 0,0396245 0,06166659 ! positive regulation of translation GO:0045727 30 19 0,000 0,0396245 0,06162673 ! negative regulation of defense response GO:0031348 25 19 0,000 0,0396245 0,06158692 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,0396245 0,06154716 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,0396245 0,06150745 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,0396245 0,06146779 ! lipid phosphorylation GO:0046834 35 19 0,000 0,0396245 0,06142819 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,0396245 0,06138863 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,0396245 0,06134913 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,0396245 0,06130968 ! bile acid metabolic process GO:0008206 29 19 0,000 0,0396245 0,06127027 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,0396245 0,06123092 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,0396245 0,06119162 ! pigmentation during development GO:0048066 41 19 0,000 0,0396245 0,06115237 ! response to vitamin A GO:0033189 27 19 0,000 0,0396245 0,06111317 ! heme metabolic process GO:0042168 36 19 0,000 0,0396245 0,06107402 ! actin filament bundle formation GO:0051017 42 19 0,000 0,0396245 0,06103492 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,0396245 0,06099587 ! plasma membrane fusion GO:0045026 28 19 0,000 0,0396245 0,06095687 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,0396245 0,06091792 ! peptide cross-linking GO:0018149 37 19 0,000 0,0396245 0,06087902 ! protein export from nucleus GO:0006611 36 19 0,000 0,0396245 0,06084017 ! heart process GO:0003015 30 19 0,000 0,0396245 0,06080137 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,0396245 0,06076262 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,0396245 0,06072391 ! visual learning GO:0008542 36 19 0,000 0,0396245 0,06068526 ! cellular pigmentation GO:0033059 36 19 0,000 0,0396245 0,06064666 ! G1 phase GO:0051318 40 19 0,000 0,0396245 0,0606081 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,0396245 0,0605696 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,0396245 0,06053114 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,0396245 0,06049273 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,0396245 0,06045437 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,0396245 0,06041606 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,0396245 0,0603778 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,0396245 0,06033959 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,0396245 0,06030142 ! cilium assembly GO:0042384 37 19 0,000 0,0396245 0,0602633 ! peptide hormone secretion GO:0030072 31 19 0,000 0,0396245 0,06022523 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,04166663 0,06328909 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,04166663 0,06324916 ! positive regulation of ossification GO:0045778 47 20 0,000 0,04166663 0,06320928 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,04166663 0,06316945 ! protein amino acid acetylation GO:0006473 39 20 0,000 0,04166663 0,06312967 ! cAMP metabolic process GO:0046058 36 20 0,000 0,04166663 0,06308994 ! response to vitamin GO:0033273 31 20 0,000 0,04166663 0,06305026 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,04166663 0,06301063 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 0,04166663 0,06297105 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,04166663 0,06293152 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,04166663 0,06289204 ! response to alkaloid GO:0043279 38 20 0,000 0,04166663 0,06285261 ! retinoid metabolic process GO:0001523 32 20 0,000 0,04166663 0,06281323 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,04166663 0,0627739 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,04166663 0,06273461 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,04166663 0,06269538 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,04166663 0,06265619 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 0,000 0,04166663 0,06261706 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,04166663 0,06257797 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,04166663 0,06253893 ! body fluid secretion GO:0007589 31 20 0,000 0,04166663 0,06249994 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,04166663 0,062461 ! peptide secretion GO:0002790 35 20 0,000 0,04166663 0,06242211 ! stem cell differentiation GO:0048863 53 20 0,000 0,04166663 0,06238327 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,04166663 0,06234447 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,04166663 0,06230573 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,04166663 0,06226703 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,04166663 0,06222837 ! diencephalon development GO:0021536 34 20 0,000 0,04166663 0,06218977 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,04166663 0,06215122 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,04166663 0,06211271 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,04166663 0,06207425 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,04166663 0,06203584 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,04166663 0,06199747 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,04166663 0,06195915 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,04166663 0,06192088 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,04166663 0,06188266 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,04166663 0,06184449 ! regulation of glucose import GO:0046324 29 20 0,000 0,04166663 0,06180636 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,04166663 0,06176828 ! actin filament-based movement GO:0030048 43 20 0,000 0,04166663 0,06173024 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,04166663 0,06169225 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,04166663 0,06165431 ! negative regulation of translation GO:0017148 29 20 0,000 0,04166663 0,06161642 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,04166663 0,06157857 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,04166663 0,06154077 ! regulation of cell killing GO:0031341 42 21 0,000 0,04370449 0,06451104 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,04370449 0,06447148 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,04370449 0,06443198 ! hormone secretion GO:0046879 38 21 0,000 0,04370449 0,06439252 ! glycerol metabolic process GO:0006071 34 21 0,000 0,04370449 0,06435312 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,04370449 0,06431376 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,04370449 0,06427444 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,04370449 0,06423518 ! axis specification GO:0009798 38 21 0,000 0,04370449 0,06419597 ! ovarian follicle development GO:0001541 35 21 0,000 0,04370449 0,0641568 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,04370449 0,06411768 ! smooth muscle contraction GO:0006939 46 21 0,000 0,04370449 0,06407861 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,04370449 0,06403958 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,04370449 0,0640006 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,04370449 0,06396167 ! cell aging GO:0007569 44 21 0,000 0,04370449 0,06392279 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,04370449 0,06388396 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,04370449 0,06384517 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,04370449 0,06380643 ! cytolysis GO:0019835 24 21 0,000 0,04370449 0,06376773 ! vasodilation GO:0042311 39 21 0,000 0,04370449 0,06372909 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,04370449 0,06369049 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,04370449 0,06365193 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,04370449 0,06361343 ! oogenesis GO:0048477 36 21 0,000 0,04370449 0,06357496 ! DNA modification GO:0006304 34 21 0,000 0,04370449 0,06353655 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,04370449 0,06349818 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,04370449 0,06345986 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,04370449 0,06342159 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,04370449 0,06338336 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,04370449 0,06334518 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,04370449 0,06330704 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,04370449 0,06326895 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,04370449 0,0632309 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,04370449 0,0631929 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,04370449 0,06315495 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,04370449 0,06311704 ! collagen catabolic process GO:0030574 28 21 0,000 0,04370449 0,06307918 ! sperm-egg recognition GO:0035036 21 21 0,000 0,04370449 0,06304136 ! gut development GO:0048565 39 21 0,000 0,04370449 0,06300359 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,04573807 0,06589569 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,04573807 0,06585626 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,04573807 0,06581687 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,04573807 0,06577753 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,04573807 0,06573824 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,04573807 0,06569899 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,04573807 0,06565979 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,04573807 0,06562064 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,04573807 0,06558153 ! regeneration GO:0031099 41 22 0,000 0,04573807 0,06554247 ! keratinization GO:0031424 28 22 0,000 0,04573807 0,06550346 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,04573807 0,06546449 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,04573807 0,06542557 ! sensory perception of taste GO:0050909 28 22 0,000 0,04573807 0,0653867 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,04573807 0,06534787 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,04573807 0,06530909 ! vacuolar transport GO:0007034 36 22 0,000 0,04573807 0,06527035 ! lysosome organization GO:0007040 41 22 0,000 0,04573807 0,06523166 ! central nervous system neuron development GO:0021954 46 22 0,000 0,04573807 0,06519301 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,04573807 0,06515442 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,04573807 0,06511586 ! fucose metabolic process GO:0006004 39 22 0,000 0,04573807 0,06507736 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,04573807 0,06503889 ! ureteric bud development GO:0001657 43 22 0,000 0,04573807 0,06500048 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,04573807 0,06496211 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,04573807 0,06492378 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,04573807 0,0648855 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,04573807 0,06484726 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,04573807 0,06480907 ! sarcomere organization GO:0045214 30 22 0,000 0,04573807 0,06477093 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,04573807 0,06473283 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,04573807 0,06469477 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,04573807 0,06465676 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,04573807 0,0646188 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,04573807 0,06458087 ! protein stabilization GO:0050821 39 22 0,000 0,04573807 0,064543 ! positive regulation of DNA replication GO:0045740 43 23 0,000 0,04776741 0,06736716 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,04776741 0,0673277 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,04776741 0,06728828 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,04776741 0,06724891 ! gluconeogenesis GO:0006094 33 23 0,000 0,04776741 0,06720958 ! viral genome replication GO:0019079 41 23 0,000 0,04776741 0,0671703 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,04776741 0,06713106 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,04776741 0,06709188 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,04776741 0,06705273 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,04776741 0,06701363 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,04776741 0,06697458 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,04776741 0,06693558 ! visual behavior GO:0007632 42 23 0,000 0,04776741 0,06689661 ! regulation of cell-matrix adhesion GO:0001952 78 23 0,000 0,04776741 0,0668577 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 48 23 0,000 0,04776741 0,06681883 ! response to ethanol GO:0045471 46 23 0,000 0,04776741 0,06678 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,04776741 0,06674122 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,04776741 0,06670249 ! peroxisome organization GO:0007031 37 23 0,000 0,04776741 0,06666379 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,04776741 0,06662515 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,04776741 0,06658655 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,04776741 0,06654799 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,04776741 0,06650948 GO:0051693|actin filament capping, ! sex determination GO:0007530 47 23 0,000 0,04776741 0,06647101 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,04776741 0,06643259 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,04776741 0,06639421 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,04776741 0,06635588 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,04776741 0,06631759 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,04776741 0,06627934 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,04776741 0,06624114 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,04776741 0,06620299 ! fatty acid transport GO:0015908 44 23 0,000 0,04776741 0,06616487 ! platelet activation GO:0030168 37 23 0,000 0,04776741 0,0661268 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,04776741 0,06608878 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,04776741 0,06605079 ! hormone transport GO:0009914 40 23 0,000 0,04776741 0,06601286 ! cell-cell recognition GO:0009988 25 23 0,000 0,04776741 0,06597496 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,04776741 0,06593711 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,04776741 0,0658993 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,04776741 0,06586154 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,04776741 0,06582382 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,04776741 0,06578614 ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,04979249 0,06853589 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,04979249 0,0684967 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,04979249 0,06845756 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,04979249 0,06841847 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,04979249 0,06837942 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,04979249 0,06834041 ! spinal cord development GO:0021510 47 24 0,000 0,04979249 0,06830145 ! vacuole organization GO:0007033 43 24 0,000 0,04979249 0,06826253 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,04979249 0,06822365 ! digestive system process GO:0022600 39 24 0,000 0,04979249 0,06818482 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,04979249 0,06814604 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,04979249 0,0681073 ! regulation of behavior GO:0050795 43 24 0,000 0,04979249 0,0680686 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,04979249 0,06802995 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,04979249 0,06799134 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,04979249 0,06795277 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,04979249 0,06791425 ! membrane depolarization GO:0051899 39 24 0,000 0,04979249 0,06787577 ! pentose metabolic process GO:0019321 35 24 0,000 0,04979249 0,06783734 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,04979249 0,06779894 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,04979249 0,0677606 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,04979249 0,06772229 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,04979249 0,06768403 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,04979249 0,06764581 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,04979249 0,06760764 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,04979249 0,06756951 ! regulation of amine transport GO:0051952 40 24 0,000 0,04979249 0,06753142 ! protein tetramerization GO:0051262 52 24 0,000 0,04979249 0,06749337 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,05181334 0,07019307 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,05181334 0,07015357 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,05181334 0,07011411 ! phototransduction GO:0007602 33 25 0,000 0,05181334 0,0700747 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,05181334 0,07003533 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 0,000 0,05181334 0,06999601 ! sperm motility GO:0030317 31 25 0,000 0,05181334 0,06995673 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,05181334 0,06991749 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,05181334 0,0698783 ! receptor metabolic process GO:0043112 46 25 0,000 0,05181334 0,06983915 ! chromosome condensation GO:0030261 45 25 0,000 0,05181334 0,06980005 ! response to starvation GO:0042594 42 25 0,000 0,05181334 0,06976099 ! osteoblast differentiation GO:0001649 60 25 0,000 0,05181334 0,06972197 ! neural crest cell development GO:0014032 54 25 0,000 0,05181334 0,069683 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,05181334 0,06964407 ! negative regulation of cell development GO:0010721 73 25 0,000 0,05181334 0,06960519 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,05181334 0,06956634 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,05181334 0,06952754 ! interaction with host GO:0051701 62 25 0,000 0,05181334 0,06948879 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,05181334 0,06945008 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,05181334 0,06941141 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,05181334 0,06937278 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 0,000 0,05181334 0,0693342 ! immunoglobulin production GO:0002377 55 25 0,000 0,05181334 0,06929566 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,05181334 0,06925716 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,05181334 0,0692187 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,05181334 0,06918029 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,05181334 0,06914192 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,05181334 0,0691036 ! telomere organization GO:0032200 43 25 0,000 0,05181334 0,06906531 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,05181334 0,06902707 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,05181334 0,06898887 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,05382995 0,07163433 ! embryonic pattern specification GO:0009880 44 26 0,000 0,05382995 0,07159473 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,05382995 0,07155517 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,05382995 0,07151566 ! initiation of viral infection GO:0019059 57 26 0,000 0,05382995 0,07147619 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,05382995 0,07143677 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,05382995 0,07139739 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,05382995 0,07135805 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,05382995 0,07131876 ! molting cycle process GO:0022404 50 26 0,000 0,05382995 0,07127951 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,05382995 0,0712403 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,05382995 0,07120113 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,05382995 0,07116201 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,05382995 0,07112293 GO:0051297|centrosome organization, ! insulin receptor signaling pathway GO:0008286 64 26 0,000 0,05382995 0,0710839 ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,05382995 0,0710449 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 0,000 0,05382995 0,07100595 ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,05382995 0,07096705 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,05382995 0,07092818 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,05382995 0,07088936 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,05382995 0,07085058 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,05382995 0,07081184 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,05382995 0,07077315 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,05382995 0,0707345 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,05382995 0,07069588 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,05382995 0,07065732 ! blastocyst development GO:0001824 49 26 0,000 0,05382995 0,07061879 ! leukocyte proliferation GO:0070661 52 26 0,000 0,05382995 0,07058031 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,05382995 0,07054186 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,05382995 0,07050346 ! neuron fate commitment GO:0048663 48 27 0,000 0,05584234 0,07309939 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,05584234 0,07305964 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,05584234 0,07301993 ! iron ion transport GO:0006826 59 27 0,000 0,05584234 0,07298027 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,05584234 0,07294065 ! protein amino acid acylation GO:0043543 55 27 0,000 0,05584234 0,07290107 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,05584234 0,07286154 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,05584234 0,07282205 ! fat cell differentiation GO:0045444 50 27 0,000 0,05584234 0,0727826 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,05584234 0,07274319 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,05584234 0,07270383 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,05584234 0,07266451 ! autophagy GO:0006914 41 27 0,000 0,05584234 0,07262523 ! male gonad development GO:0008584 44 27 0,000 0,05584234 0,07258599 ! primary neural tube formation GO:0014020 51 27 0,000 0,05584234 0,0725468 ! base-excision repair GO:0006284 41 27 0,000 0,05584234 0,07250765 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,05584234 0,07246854 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,05584234 0,07242947 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,05584234 0,07239045 ! glutathione metabolic process GO:0006749 39 27 0,000 0,05584234 0,07235147 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,05584234 0,07231253 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,05584234 0,07227363 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,05584234 0,07223477 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,05785052 0,07479224 ! circadian rhythm GO:0007623 50 28 0,000 0,05785052 0,07475207 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,05785052 0,07471194 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,05785052 0,07467186 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,05785052 0,07463182 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,05785052 0,07459183 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,05785052 0,07455188 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,05785052 0,07451197 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,05785052 0,0744721 ! synaptogenesis GO:0007416 42 28 0,000 0,05785052 0,07443227 ! peptidyl-tyrosine modification GO:0018212 50 28 0,000 0,05785052 0,07439249 ! lipid oxidation GO:0034440 43 28 0,000 0,05785052 0,07435275 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,05785052 0,07431306 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,05785052 0,0742734 ! translational initiation GO:0006413 65 29 0,000 0,05985449 0,07680529 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,05985449 0,07676435 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,05985449 0,07672345 ! regulation of pH GO:0006885 43 29 0,000 0,05985449 0,0766826 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,05985449 0,07664178 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,05985449 0,07660102 ! catechol metabolic process GO:0009712 54 29 0,000 0,05985449 0,07656029 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,05985449 0,07651961 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,05985449 0,07647898 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,05985449 0,07643838 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,05985449 0,07639783 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,05985449 0,07635732 ! cell fate determination GO:0001709 60 29 0,000 0,05985449 0,07631686 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,05985449 0,07627644 ! detection of light stimulus GO:0009583 38 29 0,000 0,05985449 0,07623606 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,05985449 0,07619572 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,05985449 0,07615543 ! tissue homeostasis GO:0001894 48 29 0,000 0,05985449 0,07611518 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,05985449 0,07607497 ! phenol metabolic process GO:0018958 55 30 0,000 0,06185427 0,07857517 ! zinc ion transport GO:0006829 45 30 0,000 0,06185427 0,07853371 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,06185427 0,07849229 ! regulation of innate immune response GO:0045088 51 30 0,000 0,06185427 0,07845091 ! acute-phase response GO:0006953 49 30 0,000 0,06185427 0,07840958 ! myofibril assembly GO:0030239 47 30 0,000 0,06185427 0,07836829 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,06185427 0,07832704 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,06185427 0,07828584 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,06185427 0,07824468 ! phospholipid transport GO:0015914 51 30 0,000 0,06185427 0,07820356 ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,06185427 0,07816249 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,06185427 0,07812146 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,06185427 0,07808047 ! eye morphogenesis GO:0048592 60 30 0,000 0,06185427 0,07803953 ! response to heat GO:0009408 50 30 0,000 0,06185427 0,07799863 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,06384986 0,0804729 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,06384986 0,08043077 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,06384986 0,08038868 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,06384986 0,08034664 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,06384986 0,08030464 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,06384986 0,08026268 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,06384986 0,08022077 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,06384986 0,0801789 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,06384986 0,08013707 ! ovulation cycle process GO:0022602 49 31 0,000 0,06384986 0,08009529 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,06384986 0,08005355 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,06384986 0,08001186 ! peptide transport GO:0015833 55 31 0,000 0,06384986 0,07997021 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,06384986 0,0799286 ! iron ion homeostasis GO:0055072 54 31 0,000 0,06384986 0,07988704 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,06384986 0,07984551 ! mesoderm formation GO:0001707 69 31 0,000 0,06384986 0,07980404 ! natural killer cell activation GO:0030101 45 31 0,000 0,06384986 0,0797626 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,06384986 0,07972121 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,06384986 0,07967986 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,06384986 0,07963855 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,06384986 0,07959729 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,06384986 0,07955607 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,06584127 0,08199488 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,06584127 0,08195246 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,06584127 0,08191009 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,06584127 0,08186775 ! cholesterol transport GO:0030301 56 32 0,000 0,06584127 0,08182547 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,06584127 0,08178322 ! spliceosome assembly GO:0000245 67 32 0,000 0,06584127 0,08174102 ! spindle organization GO:0007051 46 32 0,000 0,06584127 0,08169887 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,06584127 0,08165676 ! metanephros development GO:0001656 74 32 0,000 0,06584127 0,08161469 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,06584127 0,08157266 ! response to ionizing radiation GO:0010212 65 32 0,000 0,06584127 0,08153068 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,06584127 0,08148874 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,06584127 0,08144684 ! muscle cell development GO:0055001 49 32 0,000 0,06584127 0,08140499 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,06584127 0,08136318 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,06584127 0,08132141 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,06584127 0,08127968 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,06584127 0,081238 ! ovulation cycle GO:0042698 51 32 0,000 0,06584127 0,08119636 ! BMP signaling pathway GO:0030509 64 32 0,000 0,06584127 0,08115477 ! hindbrain development GO:0030902 61 32 0,000 0,06584127 0,08111321 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,06584127 0,0810717 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,06584127 0,08103023 ! positive regulation of catabolic process GO:0009896 64 32 0,000 0,06584127 0,08098881 ! gene silencing GO:0016458 65 32 0,000 0,06584127 0,08094742 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,06782852 0,08334801 ! post-embryonic development GO:0009791 69 33 0,000 0,06782852 0,08330547 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,06782852 0,08326296 ! protein targeting to membrane GO:0006612 68 33 0,000 0,06782852 0,0832205 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,06782852 0,08317809 ! ceramide metabolic process GO:0006672 64 33 0,000 0,06782852 0,08313572 ! formation of primary germ layer GO:0001704 72 33 0,000 0,06782852 0,08309339 ! cell fate specification GO:0001708 52 33 0,000 0,06782852 0,0830511 ! sterol transport GO:0015918 57 33 0,000 0,06782852 0,08300885 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,06782852 0,08296665 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,06782852 0,0829245 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,06782852 0,08288238 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,06782852 0,08284031 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,0698116 0,08521903 ! glial cell differentiation GO:0010001 63 34 0,000 0,0698116 0,08517581 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,0698116 0,08513264 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,0698116 0,08508951 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,0698116 0,08504643 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,0698116 0,08500339 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,0698116 0,08496039 ! mismatch repair GO:0006298 46 34 0,000 0,0698116 0,08491744 ! spermatid development GO:0007286 63 34 0,000 0,0698116 0,08487453 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,0698116 0,08483167 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,0698116 0,08478884 ! placenta development GO:0001890 53 34 0,000 0,0698116 0,08474606 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 0,000 0,0698116 0,08470333 ! regulation of muscle development GO:0048634 70 35 0,000 0,07179052 0,08706048 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,07179052 0,08701662 ! negative regulation of secretion GO:0051048 63 35 0,000 0,07179052 0,08697281 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,07179052 0,08692904 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,07179052 0,08688531 ! odontogenesis GO:0042476 66 35 0,000 0,07179052 0,08684163 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,07179052 0,08679799 ! female gonad development GO:0008585 58 35 0,000 0,07179052 0,08675439 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,07179052 0,08671084 GO:0006639|acylglycerol metabolic process, ! cytokine production GO:0001816 59 35 0,000 0,07179052 0,08666733 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,07179052 0,08662387 ! neural tube formation GO:0001841 67 35 0,000 0,07179052 0,08658045 ! vesicle localization GO:0051648 64 35 0,000 0,07179052 0,08653707 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,0737653 0,08887297 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,0737653 0,08882849 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,0737653 0,08878405 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,0737653 0,08873966 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,0737653 0,08869531 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,0737653 0,08865101 ! positive regulation of cell development GO:0010720 80 36 0,000 0,0737653 0,08860675 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,0737653 0,08856254 ! regulation of proteolysis GO:0030162 72 36 0,000 0,0737653 0,08851837 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,0737653 0,08847424 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,0737653 0,08843016 ! aerobic respiration GO:0009060 55 36 0,000 0,0737653 0,08838612 ! embryonic organ development GO:0048568 57 36 0,000 0,0737653 0,08834212 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,0737653 0,08829817 ! RNA export from nucleus GO:0006405 56 37 0,000 0,07573595 0,09061198 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,07573595 0,09056695 ! meiosis I GO:0007127 65 37 0,000 0,07573595 0,09052196 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,07573595 0,09047701 ! sister chromatid segregation GO:0000819 58 37 0,000 0,07573595 0,09043211 ! actomyosin structure organization GO:0031032 62 37 0,000 0,07573595 0,09038725 ! organic anion transport GO:0015711 68 37 0,000 0,07573595 0,09034244 ! tissue remodeling GO:0048771 76 37 0,000 0,07573595 0,09029767 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,07573595 0,09025295 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,07573595 0,09020827 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,07573595 0,09016363 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,07573595 0,09011904 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,07573595 0,09007449 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,07573595 0,09002999 ! glycogen metabolic process GO:0005977 61 37 0,000 0,07573595 0,08998553 ! pigment metabolic process GO:0042440 80 37 0,000 0,07573595 0,08994112 ! spermatid differentiation GO:0048515 66 37 0,000 0,07573595 0,08989674 ! cellular response to insulin stimulus GO:0032869 82 37 0,000 0,07573595 0,08985242 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,07770247 0,09214004 GO:0006956|complement activation, ! positive regulation of DNA metabolic process GO:0051054 72 38 0,000 0,07770247 0,09209465 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,07770247 0,09204931 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,07770247 0,09200401 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,07770247 0,09195875 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,07770247 0,09191354 ! carbohydrate homeostasis GO:0033500 53 38 0,000 0,07770247 0,09186838 GO:0042593|glucose homeostasis, ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,07770247 0,09182325 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 0,000 0,07770247 0,09177818 ! lipid homeostasis GO:0055088 67 38 0,000 0,07770247 0,09173314 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,07770247 0,09168815 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,07770247 0,09164321 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,07770247 0,09159831 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,07770247 0,09155345 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,07770247 0,09150864 ! glucan metabolic process GO:0044042 62 38 0,000 0,07770247 0,09146387 GO:0006073|cellular glucan metabolic process, ! learning GO:0007612 77 39 0,000 0,07966487 0,09372796 ! ear morphogenesis GO:0042471 60 39 0,000 0,07966487 0,09368215 ! organic ether metabolic process GO:0018904 55 39 0,000 0,07966487 0,09363638 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,07966487 0,09359066 ! segmentation GO:0035282 67 39 0,000 0,07966487 0,09354499 ! ion transmembrane transport GO:0034220 66 39 0,000 0,07966487 0,09349936 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,07966487 0,09345377 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,07966487 0,09340823 ! RNA modification GO:0009451 57 39 0,000 0,07966487 0,09336273 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,08162316 0,09561116 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,08162316 0,09556464 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,08162316 0,09551815 ! feeding behavior GO:0007631 59 40 0,000 0,08162316 0,09547172 ! negative regulation of binding GO:0051100 72 40 0,000 0,08162316 0,09542533 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,08162316 0,09537898 ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,08162316 0,09533268 ! maintenance of protein location GO:0045185 91 40 0,000 0,08162316 0,09528643 ! cytokinesis GO:0000910 72 40 0,000 0,08162316 0,09524022 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,08357735 0,09747315 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,08357735 0,09742592 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,08357735 0,09737874 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,08357735 0,09733161 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,08357735 0,09728452 ! T cell differentiation GO:0030217 81 41 0,000 0,08357735 0,09723748 ! female gamete generation GO:0007292 61 41 0,000 0,08357735 0,09719048 ! polyol metabolic process GO:0019751 66 41 0,000 0,08357735 0,09714353 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,08357735 0,09709662 ! positive regulation of transcription factor activity GO:0051091 62 42 0,000 0,08552744 0,0993142 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 0,000 0,08552744 0,0992663 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,08552744 0,09921843 ! regulation of tube size GO:0035150 71 42 0,000 0,08552744 0,09917062 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,08552744 0,09912285 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,08552744 0,09907512 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,08552744 0,09902744 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,08552744 0,09897981 ! regulation of protein secretion GO:0050708 71 42 0,000 0,08552744 0,09893223 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,08552744 0,09888469 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,08747345 0,10108604 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,08747345 0,10103751 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,08747345 0,10098903 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,08747345 0,10094059 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,08747345 0,1008922 ! glucose transport GO:0015758 65 43 0,000 0,08747345 0,10084386 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,08747345 0,10079556 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,08747345 0,10074731 ! neural tube development GO:0021915 77 43 0,000 0,08747345 0,10069911 ! striated muscle contraction GO:0006941 77 43 0,000 0,08747345 0,10065095 ! phagocytosis GO:0006909 90 43 0,000 0,08747345 0,10060283 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,08747345 0,10055477 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,08941539 0,10273802 ! hexose transport GO:0008645 67 44 0,000 0,08941539 0,10268898 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,08941539 0,10263999 ! male sex differentiation GO:0046661 76 44 0,000 0,08941539 0,10259104 ! double-strand break repair GO:0006302 81 44 0,000 0,08941539 0,10254215 ! biopolymer methylation GO:0043414 84 44 0,000 0,08941539 0,10249329 ! B cell differentiation GO:0030183 107 44 0,000 0,08941539 0,10244449 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,08941539 0,10239573 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,08941539 0,10234701 ! developmental growth GO:0048589 82 44 0,000 0,08941539 0,10229835 ! maintenance of location in cell GO:0051651 97 44 0,000 0,08941539 0,10224972 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,09135325 0,10441612 ! glycolysis GO:0006096 65 45 0,000 0,09135325 0,10436654 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,09135325 0,104317 ! leukocyte migration GO:0050900 68 45 0,000 0,09135325 0,10426752 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,09135325 0,10421808 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,09135325 0,10416868 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,09135325 0,10411934 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,09135325 0,10407004 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,09135325 0,10402079 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,09135325 0,10397158 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,09135325 0,10392242 ! cell growth GO:0016049 84 45 0,000 0,09135325 0,10387331 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,09328706 0,10602204 ! regulation of gene-specific transcription GO:0032583 96 46 0,000 0,09328706 0,10597198 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,09328706 0,10592197 ! pigmentation GO:0043473 100 46 0,000 0,09328706 0,10587201 ! response to insulin stimulus GO:0032868 95 46 0,000 0,09328706 0,10582209 ! positive regulation of defense response GO:0031349 76 47 0,000 0,09521681 0,10796025 ! response to calcium ion GO:0051592 81 47 0,000 0,09521681 0,1079094 ! endosome transport GO:0016197 108 47 0,000 0,09521681 0,10785859 ! positive regulation of DNA binding GO:0043388 73 47 0,000 0,09521681 0,10780783 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,09521681 0,10775713 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,09521681 0,10770646 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,09521681 0,10765585 ! JNK cascade GO:0007254 91 47 0,000 0,09521681 0,10760528 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,09521681 0,10755476 ! methylation GO:0032259 90 47 0,000 0,09521681 0,10750429 ! mitochondrial transport GO:0006839 82 48 0,000 0,09714252 0,10962707 ! Notch signaling pathway GO:0007219 96 48 0,000 0,09714252 0,10957567 ! cellular component disassembly GO:0022411 86 48 0,000 0,09714252 0,10952432 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,09714252 0,10947302 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,09714252 0,10942177 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,09714252 0,10937057 ! activation of caspase activity GO:0006919 84 48 0,000 0,09714252 0,10931941 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,09714252 0,10926831 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,09714252 0,10921725 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,0990642 0,11132576 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,0990642 0,11127379 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,0990642 0,11122187 ! regulation of ion transport GO:0043269 77 49 0,000 0,0990642 0,11116999 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,0990642 0,11111816 ! peptide metabolic process GO:0006518 76 49 0,000 0,0990642 0,11106638 ! response to temperature stimulus GO:0009266 76 49 0,000 0,0990642 0,11101465 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,0990642 0,11096297 ! endocrine system development GO:0035270 104 49 0,000 0,0990642 0,11091134 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,0990642 0,11085975 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,0990642 0,11080821 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,0990642 0,11075672 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,0990642 0,11070528 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,10098185 0,11279588 ! regulation of ossification GO:0030278 117 50 0,000 0,10098185 0,11274354 ! inner ear development GO:0048839 79 50 0,000 0,10098185 0,11269125 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,10098185 0,112639 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,10098185 0,11258681 ! positive regulation of binding GO:0051099 78 51 0,000 0,10289548 0,11466722 ! viral infectious cycle GO:0019058 99 51 0,000 0,10289548 0,11461413 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,10289548 0,11456109 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,10289548 0,11450811 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,10289548 0,11445517 ! excretion GO:0007588 83 51 0,000 0,10289548 0,11440228 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,10289548 0,11434943 ! chromatin remodeling GO:0006338 109 51 0,000 0,10289548 0,11429664 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,10289548 0,1142439 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,10289548 0,1141912 ! vesicle organization GO:0016050 107 51 0,000 0,10289548 0,11413855 ! regulation of cell shape GO:0008360 125 51 0,000 0,10289548 0,11408596 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,10289548 0,11403341 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,1048051 0,11609626 ! membrane fusion GO:0006944 110 52 0,000 0,1048051 0,11604283 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,1048051 0,11598945 ! amino acid activation GO:0043038 92 52 0,000 0,1048051 0,11593613 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,1048051 0,11588285 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,10671072 0,11793569 ! regulation of translational initiation GO:0006446 82 53 0,000 0,10671072 0,11788154 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,10671072 0,11782744 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,10671072 0,11777339 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,10671072 0,11771939 ! cell maturation GO:0048469 100 53 0,000 0,10671072 0,11766544 ! regulation of neuron apoptosis GO:0043523 100 53 0,000 0,10671072 0,11761154 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,10671072 0,11755769 ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,10861235 0,11959785 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,10861235 0,11954314 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,10861235 0,11948848 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,10861235 0,11943387 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,10861235 0,11937931 ! chloride transport GO:0006821 90 55 0,000 0,11050999 0,12140961 ! positive regulation of caspase activity GO:0043280 95 55 0,000 0,11050999 0,12135419 GO:0010952|positive regulation of peptidase activity, ! glucose catabolic process GO:0006007 82 55 0,000 0,11050999 0,12129883 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,11050999 0,12124352 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,11050999 0,12118826 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,11050999 0,12113305 ! aging GO:0007568 103 55 0,000 0,11050999 0,12107789 ! gastrulation GO:0007369 112 55 0,000 0,11050999 0,12102278 ! heart morphogenesis GO:0003007 97 55 0,000 0,11050999 0,12096771 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,11050999 0,1209127 ! RNA elongation GO:0006354 79 55 0,000 0,11050999 0,12085774 ! nuclear export GO:0051168 97 55 0,000 0,11050999 0,12080283 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,11050999 0,12074797 ! regulation of actin filament length GO:0030832 105 56 0,000 0,11240366 0,12276132 ! sensory perception of smell GO:0007608 80 56 0,000 0,11240366 0,12270562 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,11240366 0,12264998 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,11240366 0,12259438 ! regulation of DNA replication GO:0006275 101 56 0,000 0,11240366 0,12253883 ! proton transport GO:0015992 94 56 0,000 0,11240366 0,12248333 ! positive regulation of organelle organization GO:0010638 100 56 0,000 0,11240366 0,12242788 ! regulation of bone remodeling GO:0046850 137 57 0,000 0,11429335 0,12442978 ! lipid modification GO:0030258 97 57 0,000 0,11429335 0,1243735 ! maintenance of location GO:0051235 118 57 0,000 0,11429335 0,12431727 ! hydrogen transport GO:0006818 97 58 0,000 0,11617909 0,12631129 ! regulation of tissue remodeling GO:0034103 140 58 0,000 0,11617909 0,12625424 ! regulation of endocytosis GO:0030100 91 58 0,000 0,11617909 0,12619724 ! positive regulation of secretion GO:0051047 95 59 0,000 0,11806087 0,12818342 ! regulation of cellular component size GO:0032535 109 59 0,000 0,11806087 0,1281256 ! skeletal system morphogenesis GO:0048705 105 59 0,000 0,11806087 0,12806783 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,11806087 0,12801012 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,11806087 0,12795246 ! DNA catabolic process GO:0006308 86 59 0,000 0,11806087 0,12789485 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,11806087 0,12783729 ! establishment of organelle localization GO:0051656 109 59 0,000 0,11806087 0,12777978 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,11993871 0,12975384 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,11993871 0,12969552 ! regulation of heart contraction GO:0008016 110 60 0,000 0,11993871 0,12963726 ! camera-type eye development GO:0043010 116 60 0,000 0,11993871 0,12957905 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,11993871 0,12952089 ! kidney development GO:0001822 122 60 0,000 0,11993871 0,12946278 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,12181262 0,13142653 ! mesoderm development GO:0007498 119 61 0,000 0,12181262 0,13136762 ! tRNA processing GO:0008033 89 61 0,000 0,12181262 0,13130876 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,12181262 0,13124996 ! response to peptide hormone stimulus GO:0043434 122 61 0,000 0,12181262 0,13119121 ! ear development GO:0043583 103 62 0,000 0,12368259 0,13314555 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,12368259 0,13308601 ! gonad development GO:0008406 98 62 0,000 0,12368259 0,13302651 ! regulation of homeostatic process GO:0032844 134 62 0,000 0,12368259 0,13296708 ! regulation of mitosis GO:0007088 105 63 0,000 0,12554865 0,13491293 GO:0051783|regulation of nuclear division, ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,12554865 0,1348527 ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,12554865 0,13479252 ! detection of external stimulus GO:0009581 91 63 0,000 0,12554865 0,1347324 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,12554865 0,13467233 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,12741079 0,1366089 ! cell redox homeostasis GO:0045454 102 64 0,000 0,12741079 0,13654805 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,12741079 0,13648725 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,12741079 0,13642651 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,12741079 0,13636582 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,12926903 0,13829315 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,12926903 0,13823169 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,12926903 0,13817028 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 0,000 0,12926903 0,13810892 ! myeloid cell differentiation GO:0030099 111 65 0,000 0,12926903 0,13804762 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,13112338 0,13996577 ! actin filament organization GO:0007015 148 66 0,000 0,13112338 0,1399037 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,13112338 0,13984169 ! extracellular matrix organization GO:0030198 133 66 0,000 0,13112338 0,13977973 ! secondary metabolic process GO:0019748 116 66 0,000 0,13112338 0,13971782 ! developmental maturation GO:0021700 116 66 0,000 0,13112338 0,13965597 ! cell projection assembly GO:0030031 120 66 0,000 0,13112338 0,13959418 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,13297384 0,14150157 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,13297384 0,14143901 ! activation of MAPK activity GO:0000187 115 67 0,000 0,13297384 0,14137651 ! lung development GO:0030324 144 67 0,000 0,13297384 0,14131407 ! chromosome segregation GO:0007059 113 67 0,000 0,13297384 0,14125168 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,13297384 0,14118934 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,13297384 0,14112706 ! hexose catabolic process GO:0019320 104 67 0,000 0,13297384 0,14106484 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,13297384 0,14100267 ! adaptive immune response GO:0002250 119 67 0,000 0,13297384 0,14094055 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,13297384 0,14087849 ! amino acid transport GO:0006865 125 68 0,000 0,13482041 0,14277197 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,13482041 0,14270916 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,13482041 0,1426464 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,13482041 0,1425837 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,13482041 0,14252105 ! cell cycle checkpoint GO:0000075 137 69 0,000 0,13666312 0,14440556 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,13666312 0,14434217 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,13666312 0,14427884 ! urogenital system development GO:0001655 137 69 0,000 0,13666312 0,14421556 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,13666312 0,14415233 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,13666312 0,14408916 ! antigen processing and presentation GO:0019882 104 69 0,000 0,13666312 0,14402605 ! appendage morphogenesis GO:0035107 135 70 0,000 0,13850196 0,14590005 GO:0035108|limb morphogenesis, ! respiratory tube development GO:0030323 150 70 0,000 0,13850196 0,1458362 ! amine catabolic process GO:0009310 117 71 0,000 0,14033695 0,14770372 ! reproductive structure development GO:0048608 113 71 0,000 0,14033695 0,14763914 ! appendage development GO:0048736 136 71 0,000 0,14033695 0,14757461 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,14033695 0,14751014 ! B cell activation GO:0042113 160 71 0,000 0,14033695 0,14744572 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,14033695 0,14738136 ! regulation of immune effector process GO:0002697 137 71 0,000 0,14033695 0,14731706 ! acute inflammatory response GO:0002526 113 72 0,000 0,14216809 0,14917419 ! phosphoinositide metabolic process GO:0030384 128 72 0,000 0,14216809 0,14910917 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 0,000 0,14216809 0,14904419 ! carbohydrate transport GO:0008643 110 72 0,000 0,14216809 0,14897928 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,14216809 0,14891442 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,14216809 0,14884962 ! respiratory system development GO:0060541 153 72 0,000 0,14216809 0,14878487 ! learning or memory GO:0007611 147 73 0,000 0,14399539 0,1506317 ! regulation of blood pressure GO:0008217 125 73 0,000 0,14399539 0,15056624 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,14399539 0,15050083 ! fertilization GO:0009566 90 73 0,000 0,14399539 0,15043548 ! regulation of transcription factor activity GO:0051090 126 74 0,000 0,14581886 0,15227438 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 126 74 0,000 0,14581886 0,15220832 ! neurotransmitter transport GO:0006836 123 74 0,000 0,14581886 0,15214231 ! meiosis GO:0007126 121 74 0,000 0,14581886 0,15207637 GO:0051327|M phase of meiotic cell cycle, ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,14581886 0,15201048 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,14581886 0,15194464 ! eye development GO:0001654 143 74 0,000 0,14581886 0,15187886 ! organelle localization GO:0051640 136 74 0,000 0,14581886 0,15181314 ! cell-matrix adhesion GO:0007160 163 75 0,000 0,14763851 0,15364111 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,14763851 0,15357468 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,14763851 0,15350832 ! meiotic cell cycle GO:0051321 122 75 0,000 0,14763851 0,15344201 ! rhythmic process GO:0048511 128 75 0,000 0,14763851 0,15337575 ! lymphocyte differentiation GO:0030098 167 75 0,000 0,14763851 0,15330956 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,14945433 0,15512818 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,14945433 0,15506129 ! defense response to bacterium GO:0042742 89 76 0,000 0,14945433 0,15499445 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,14945433 0,15492767 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,14945433 0,15486095 ! regulation of catabolic process GO:0009894 161 76 0,000 0,14945433 0,15479429 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,15126636 0,15660364 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,15126636 0,15653628 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,15126636 0,15646898 ! blood coagulation GO:0007596 146 78 0,000 0,15307458 0,15827135 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,15307458 0,15820336 ! negative regulation of organelle organization GO:0010639 161 78 0,000 0,15307458 0,15813544 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,15307458 0,15806757 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,154879 0,15986224 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,154879 0,15979369 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,154879 0,1597252 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 0,000 0,154879 0,15965676 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,15667965 0,16144378 ! response to metal ion GO:0010038 140 80 0,000 0,15667965 0,16137467 ! muscle cell differentiation GO:0042692 159 80 0,000 0,15667965 0,16130562 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,15667965 0,16123663 ! protein import into nucleus GO:0006606 158 80 0,000 0,15667965 0,16116769 ! inorganic anion transport GO:0015698 138 80 0,000 0,15667965 0,16109882 ! T cell activation GO:0042110 168 81 0,000 0,15847652 0,16287676 ! response to hypoxia GO:0001666 171 81 0,000 0,15847652 0,16280721 ! digestion GO:0007586 112 81 0,000 0,15847652 0,16273773 ! cell-substrate adhesion GO:0031589 171 81 0,000 0,15847652 0,1626683 ! nuclear import GO:0051170 161 81 0,000 0,15847652 0,16259893 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,16026961 0,16436858 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,16026961 0,16429855 ! response to drug GO:0042493 143 82 0,000 0,16026961 0,16422857 ! response to nutrient GO:0007584 125 82 0,000 0,16026961 0,16415866 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,16026961 0,1640888 ! cellular response to hormone stimulus GO:0032870 167 82 0,000 0,16026961 0,16401901 ! response to oxygen levels GO:0070482 176 83 0,000 0,16205895 0,16577969 ! regulation of lyase activity GO:0051339 160 83 0,000 0,16205895 0,16570924 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,16384454 0,16746387 ! hemostasis GO:0007599 158 84 0,000 0,16384454 0,16739276 ! negative regulation of transport GO:0051051 153 84 0,000 0,16384454 0,16732171 ! regulation of ligase activity GO:0051340 142 84 0,000 0,16384454 0,16725072 ! nucleosome assembly GO:0006334 122 85 0,000 0,16562637 0,1689979 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,16562637 0,16892626 ! amine biosynthetic process GO:0009309 138 86 0,000 0,16740447 0,17066744 ! response to inorganic substance GO:0010035 153 86 0,000 0,16740447 0,17059516 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,16740447 0,17052293 ! chromatin assembly GO:0031497 124 86 0,000 0,16740447 0,17045077 ! tube morphogenesis GO:0035239 176 86 0,000 0,16740447 0,17037867 ! alcohol catabolic process GO:0046164 130 86 0,000 0,16740447 0,17030662 ! amine transport GO:0015837 155 86 0,000 0,16740447 0,17023464 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,16917884 0,17196633 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,16917884 0,17189371 ! protein localization in nucleus GO:0034504 176 87 0,000 0,16917884 0,17182115 ! cellular respiration GO:0045333 135 88 0,000 0,17094949 0,17354619 ! positive regulation of protein modification process GO:0031401 136 88 0,000 0,17094949 0,173473 ! regulation of DNA binding GO:0051101 155 88 0,000 0,17094949 0,17339986 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,17094949 0,17332679 ! cellular defense response GO:0006968 114 89 0,000 0,17271643 0,17504453 ! regulation of cell morphogenesis GO:0022604 215 89 0,000 0,17271643 0,17497083 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,17447965 0,17668268 ! regulation of cell cycle process GO:0010564 149 90 0,000 0,17447965 0,17660835 ! sex differentiation GO:0007548 145 90 0,000 0,17447965 0,17653408 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,17447965 0,17645987 ! sterol metabolic process GO:0016125 152 91 0,000 0,17623918 0,17816448 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,17623918 0,17808965 ! regulation of defense response GO:0031347 149 92 0,000 0,17799501 0,17978841 ! nucleosome organization GO:0034728 138 92 0,000 0,17799501 0,17971297 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,17799501 0,17963758 ! vitamin metabolic process GO:0006766 139 92 0,000 0,17799501 0,17956226 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,17974716 0,18125384 GO:0010498|proteasomal protein catabolic process, ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,17974716 0,18117791 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,17974716 0,18110204 ! negative regulation of multicellular organismal process GO:0051241 166 93 0,000 0,17974716 0,18102623 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,18149564 0,18271067 ! female pregnancy GO:0007565 164 94 0,000 0,18149564 0,18263425 ! transcription initiation GO:0006352 153 94 0,000 0,18149564 0,1825579 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,18324044 0,1842359 ! leukocyte differentiation GO:0002521 202 96 0,000 0,18498159 0,18590881 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,18498159 0,18583119 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,18498159 0,18575363 ! positive regulation of immune response GO:0050778 156 96 0,000 0,18498159 0,18567613 ! detection of stimulus GO:0051606 151 96 0,000 0,18498159 0,1855987 ! regulation of DNA metabolic process GO:0051052 178 97 0,000 0,18671907 0,1872639 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,18671907 0,18718587 ! protein ubiquitination GO:0016567 217 97 0,000 0,18671907 0,18710791 ! hormone metabolic process GO:0042445 157 97 0,000 0,18671907 0,18703001 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,18845292 0,18868819 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,18845292 0,1886097 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,19018312 0,1902622 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,19018312 0,19018312